locus-tag	class	description
B9N48_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B9N48_RS00015	COG0592	DNA-directed DNA polymerase activity
B9N48_RS00020	COG2501	S4 domain
B9N48_RS00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B9N48_RS00035	COG0187	DNA topoisomerase II activity
B9N48_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B9N48_RS00075	COG0516	GMP reductase activity
B9N48_RS00075	COG0517	IMP dehydrogenase activity
B9N48_RS00080	COG1686	Belongs to the peptidase S11 family
B9N48_RS00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
B9N48_RS00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B9N48_RS00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B9N48_RS00105	COG1428	Deoxynucleoside kinase
B9N48_RS00110	COG1428	Deoxynucleoside kinase
B9N48_RS00115	COG3858	chitin binding
B9N48_RS00115	COG1388	LysM domain
B9N48_RS00120	COG1335	isochorismatase
B9N48_RS00125	COG0590	tRNA wobble adenosine to inosine editing
B9N48_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B9N48_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B9N48_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B9N48_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
B9N48_RS00195	COG3853	Toxic anion resistance protein (TelA)
B9N48_RS00200	COG1982	Orn Lys Arg decarboxylase major
B9N48_RS00205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B9N48_RS00210	COG3870	Protein conserved in bacteria
B9N48_RS00215	COG1728	Protein conserved in bacteria
B9N48_RS00220	COG0470	DNA polymerase III
B9N48_RS00225	COG1774	PSP1 C-terminal conserved region
B9N48_RS00230	COG4467	Involved in initiation control of chromosome replication
B9N48_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B9N48_RS00240	COG2827	Endonuclease containing a URI domain
B9N48_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B9N48_RS00250	COG2002	toxin-antitoxin pair type II binding
B9N48_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9N48_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9N48_RS00260	COG0084	hydrolase, TatD family'
B9N48_RS00265	COG3583	domain protein
B9N48_RS00265	COG3584	3D domain protein
B9N48_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B9N48_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B9N48_RS00285	COG4466	Protein conserved in bacteria
B9N48_RS00295	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B9N48_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B9N48_RS00305	COG0251	oxidation-reduction process
B9N48_RS00310	COG2088	sporulation resulting in formation of a cellular spore
B9N48_RS00315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B9N48_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B9N48_RS00325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B9N48_RS00330	COG0193	aminoacyl-tRNA hydrolase activity
B9N48_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B9N48_RS00345	COG2002	toxin-antitoxin pair type II binding
B9N48_RS00350	COG2244	polysaccharide biosynthetic process
B9N48_RS00355	COG3956	TIGRFAM MazG family protein
B9N48_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B9N48_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B9N48_RS00380	COG1098	S1 RNA binding domain
B9N48_RS00395	COG2208	phosphoserine phosphatase activity
B9N48_RS00400	COG2304	oxidoreductase activity
B9N48_RS00405	COG0515	serine threonine protein kinase
B9N48_RS00410	COG0037	tRNA processing
B9N48_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B9N48_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B9N48_RS00425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B9N48_RS00430	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B9N48_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B9N48_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B9N48_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B9N48_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
B9N48_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B9N48_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B9N48_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B9N48_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B9N48_RS00475	COG1396	sequence-specific DNA binding
B9N48_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B9N48_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B9N48_RS00565	COG4463	regulation of RNA biosynthetic process
B9N48_RS00570	COG3880	PFAM UvrB UvrC protein
B9N48_RS00575	COG3869	Catalyzes the specific phosphorylation of arginine residues in
B9N48_RS00580	COG0542	response to heat
B9N48_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B9N48_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
B9N48_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
B9N48_RS00600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B9N48_RS00605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B9N48_RS00610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B9N48_RS00620	COG1045	serine acetyltransferase
B9N48_RS00625	COG0215	cysteine-tRNA ligase activity
B9N48_RS00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
B9N48_RS00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9N48_RS00640	COG3688	RNA-binding protein containing a PIN domain
B9N48_RS00645	COG1595	DNA-templated transcription, initiation
B9N48_RS00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B9N48_RS00660	COG0250	Participates in transcription elongation, termination and antitermination
B9N48_RS00670	COG0081	regulation of translation
B9N48_RS00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B9N48_RS00685	COG2813	Specifically methylates the guanine in position
B9N48_RS00690	COG0085	RNA polymerase activity
B9N48_RS00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B9N48_RS00700	COG1358	cellular component organization or biogenesis
B9N48_RS00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B9N48_RS00710	COG0049	tRNA binding
B9N48_RS00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B9N48_RS00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B9N48_RS00725	COG0596	Alpha beta hydrolase
B9N48_RS00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B9N48_RS00740	COG0088	Forms part of the polypeptide exit tunnel
B9N48_RS00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B9N48_RS00770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B9N48_RS00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B9N48_RS00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B9N48_RS00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B9N48_RS00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B9N48_RS00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B9N48_RS00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B9N48_RS00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B9N48_RS00830	COG0200	Binds to the 23S rRNA
B9N48_RS00835	COG0201	protein transport
B9N48_RS00840	COG0563	adenylate kinase activity
B9N48_RS00845	COG0024	Methionine aminopeptidase
B9N48_RS00850	COG2163	COG2163 Ribosomal protein L14E L6E L27E
B9N48_RS00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B9N48_RS00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B9N48_RS00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B9N48_RS00875	COG0202	RNA polymerase activity
B9N48_RS00880	COG0203	ribosomal protein L17
B9N48_RS00885	COG1122	ATPase activity
B9N48_RS00890	COG1122	ATPase activity
B9N48_RS00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B9N48_RS00900	COG0101	tRNA pseudouridine synthase activity
B9N48_RS00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B9N48_RS00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B9N48_RS00915	COG2226	methyltransferase
B9N48_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9N48_RS00930	COG0489	protein tyrosine kinase activity
B9N48_RS00940	COG2194	sulfuric ester hydrolase activity
B9N48_RS00945	COG0726	polysaccharide deacetylase
B9N48_RS01030	COG0659	secondary active sulfate transmembrane transporter activity
B9N48_RS01035	COG0385	Bile acid
B9N48_RS01040	COG2819	hydrolase of the alpha beta superfamily
B9N48_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9N48_RS01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9N48_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9N48_RS01060	COG2207	Transcriptional regulator
B9N48_RS01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9N48_RS01065	COG3876	Protein conserved in bacteria
B9N48_RS01070	COG1472	Belongs to the glycosyl hydrolase 3 family
B9N48_RS01075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B9N48_RS01080	COG1263	PTS System
B9N48_RS01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9N48_RS01085	COG1737	Transcriptional regulator
B9N48_RS01090	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B9N48_RS01095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9N48_RS01100	COG1683	Conserved Protein
B9N48_RS01130	COG1595	DNA-templated transcription, initiation
B9N48_RS01135	COG5662	AntiSigma factor
B9N48_RS01140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B9N48_RS01145	COG4856	YbbR-like protein
B9N48_RS01150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9N48_RS01155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B9N48_RS01160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B9N48_RS01165	COG2169	Transcriptional regulator
B9N48_RS01170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B9N48_RS01175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B9N48_RS01180	COG3002	Belongs to the UPF0753 family
B9N48_RS01185	COG0288	reversible hydration of carbon dioxide
B9N48_RS01195	COG5609	conserved protein (DUF2294)
B9N48_RS01200	COG0640	Transcriptional regulator
B9N48_RS01205	COG2814	Major facilitator Superfamily
B9N48_RS01210	COG0596	Alpha beta hydrolase
B9N48_RS01215	COG0745	RESPONSE REGULATOR receiver
B9N48_RS01220	COG0642	Histidine kinase
B9N48_RS01230	COG0515	serine threonine protein kinase
B9N48_RS01245	COG1113	amino acid transport
B9N48_RS01260	COG2602	Beta-lactamase
B9N48_RS01265	COG2124	cytochrome p450
B9N48_RS01275	COG0531	amino acid
B9N48_RS01280	COG0584	glycerophosphoryl diester phosphodiesterase
B9N48_RS01285	COG2271	Major facilitator Superfamily
B9N48_RS01300	COG1846	Transcriptional regulator
B9N48_RS01300	COG0456	acetyltransferase
B9N48_RS01305	COG2271	Major facilitator Superfamily
B9N48_RS01310	COG3409	Peptidoglycan-binding domain 1 protein
B9N48_RS01315	COG0697	spore germination
B9N48_RS01320	COG2207	Transcriptional regulator
B9N48_RS01320	COG1917	Cupin 2, conserved barrel domain protein
B9N48_RS01325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B9N48_RS01330	COG3591	Belongs to the peptidase S1B family
B9N48_RS01340	COG0596	Alpha beta hydrolase
B9N48_RS01345	COG1183	phosphatidylcholine synthase activity
B9N48_RS01350	COG0586	Pfam SNARE associated Golgi protein
B9N48_RS01355	COG0688	phosphatidylethanolamine metabolic process
B9N48_RS01365	COG2312	Erythromycin esterase
B9N48_RS01370	COG1054	Belongs to the UPF0176 family
B9N48_RS01375	COG1301	dicarboxylic acid transport
B9N48_RS01380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9N48_RS01380	COG2190	(PTS) system
B9N48_RS01380	COG1263	PTS System
B9N48_RS01385	COG0363	glucosamine-6-phosphate deaminase activity
B9N48_RS01390	COG2188	Transcriptional regulator
B9N48_RS01400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B9N48_RS01405	COG0833	amino acid
B9N48_RS01410	COG2040	homocysteine
B9N48_RS01420	COG1115	amino acid carrier protein
B9N48_RS01425	COG2066	Belongs to the glutaminase family
B9N48_RS01430	COG4191	Histidine kinase
B9N48_RS01435	COG0784	Response regulator, receiver
B9N48_RS01445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B9N48_RS01450	COG1012	belongs to the aldehyde dehydrogenase family
B9N48_RS01455	COG2271	Major facilitator Superfamily
B9N48_RS01460	COG4948	Mandelate Racemase Muconate Lactonizing
B9N48_RS01465	COG2186	Transcriptional regulator
B9N48_RS01470	COG2721	sulfolactate sulfo-lyase activity
B9N48_RS01475	COG3173	Aminoglycoside phosphotransferase
B9N48_RS01485	COG0697	spore germination
B9N48_RS01490	COG0745	RESPONSE REGULATOR receiver
B9N48_RS01495	COG2205	protein histidine kinase activity
B9N48_RS01500	COG1131	(ABC) transporter
B9N48_RS01515	COG3773	Cell wall hydrolase
B9N48_RS01520	COG2304	oxidoreductase activity
B9N48_RS01530	COG3540	Alkaline phosphatase
B9N48_RS01535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B9N48_RS01540	COG0805	protein transport
B9N48_RS01545	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
B9N48_RS01550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B9N48_RS01555	COG0477	Major facilitator Superfamily
B9N48_RS01560	COG1309	transcriptional regulator
B9N48_RS01565	COG0252	asparaginase activity
B9N48_RS01570	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
B9N48_RS01575	COG1714	RDD family
B9N48_RS01580	COG1405	negative regulation of cell septum assembly
B9N48_RS01580	COG3012	SEC-C Motif Domain Protein
B9N48_RS01585	COG3290	protein histidine kinase activity
B9N48_RS01590	COG3279	Response regulator of the LytR AlgR family
B9N48_RS01595	COG4555	ABC transporter
B9N48_RS01600	COG1668	transmembrane transport
B9N48_RS01605	COG0667	Aldo Keto reductase
B9N48_RS01615	COG1595	DNA-templated transcription, initiation
B9N48_RS01625	COG1595	DNA-templated transcription, initiation
B9N48_RS01630	COG1876	peptidase activity
B9N48_RS01635	COG0457	Tetratricopeptide repeat
B9N48_RS01640	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS01645	COG0366	Alpha amylase catalytic
B9N48_RS01650	COG0803	Belongs to the bacterial solute-binding protein 9 family
B9N48_RS01655	COG1121	(ABC) transporter
B9N48_RS01660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B9N48_RS01665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9N48_RS01670	COG2310	stress, protein
B9N48_RS01675	COG2310	stress, protein
B9N48_RS01680	COG2310	stress, protein
B9N48_RS01685	COG0861	Integral membrane protein TerC family
B9N48_RS01695	COG3853	Toxic anion resistance protein (TelA)
B9N48_RS01700	COG0477	Major facilitator Superfamily
B9N48_RS01710	COG2814	Major facilitator Superfamily
B9N48_RS01715	COG0640	Transcriptional regulator
B9N48_RS01720	COG4175	Glycine betaine
B9N48_RS01720	COG0517	IMP dehydrogenase activity
B9N48_RS01725	COG4176	ABC-type proline glycine betaine transport system permease component
B9N48_RS01730	COG2113	Glycine betaine
B9N48_RS01735	COG1473	amidohydrolase
B9N48_RS01740	COG1288	antiporter activity
B9N48_RS01750	COG0366	Alpha amylase catalytic
B9N48_RS01755	COG0039	L-malate dehydrogenase activity
B9N48_RS01760	COG1620	l-lactate permease
B9N48_RS01765	COG2814	Major facilitator Superfamily
B9N48_RS01770	COG1846	Transcriptional regulator
B9N48_RS01775	COG1280	lysine exporter protein (LysE YggA)
B9N48_RS01780	COG3403	YqcI/YcgG family
B9N48_RS01785	COG1113	amino acid transport
B9N48_RS01790	COG3665	Urea carboxylase-associated protein
B9N48_RS01795	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B9N48_RS01800	COG1660	Displays ATPase and GTPase activities
B9N48_RS01805	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B9N48_RS01810	COG2226	methyltransferase
B9N48_RS01815	COG0583	DNA-binding transcription factor activity
B9N48_RS01820	COG3458	cephalosporin-C deacetylase activity
B9N48_RS01825	COG3541	Predicted nucleotidyltransferase
B9N48_RS01830	COG0506	proline dehydrogenase activity
B9N48_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
B9N48_RS01840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9N48_RS01845	COG2508	Transcriptional regulator
B9N48_RS01850	COG3689	TIGRFAM TIGR03943 family protein
B9N48_RS01855	COG0701	Predicted permease
B9N48_RS01860	COG2267	carboxylic ester hydrolase activity
B9N48_RS01865	COG0492	ferredoxin-NADP+ reductase activity
B9N48_RS01870	COG1587	Uroporphyrinogen-III synthase
B9N48_RS01870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B9N48_RS01875	COG2146	nitrite reductase [NAD(P)H] activity
B9N48_RS01880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B9N48_RS01885	COG0243	molybdopterin cofactor binding
B9N48_RS01890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B9N48_RS01895	COG2223	nitrite transmembrane transporter activity
B9N48_RS01900	COG1469	GTP cyclohydrolase I activity
B9N48_RS01905	COG1376	ErfK ybiS ycfS ynhG family protein
B9N48_RS01915	COG0523	cobalamin synthesis protein
B9N48_RS01920	COG0765	amino acid transport
B9N48_RS01925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9N48_RS01930	COG1714	RDD family
B9N48_RS01940	COG2723	6-phospho-beta-galactosidase activity
B9N48_RS01950	COG3209	COG3209 Rhs family protein
B9N48_RS01955	COG0840	transmembrane signaling receptor activity
B9N48_RS01955	COG3290	protein histidine kinase activity
B9N48_RS01960	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B9N48_RS01965	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
B9N48_RS01970	COG1733	regulation of RNA biosynthetic process
B9N48_RS01975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9N48_RS01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9N48_RS01990	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B9N48_RS01995	COG2814	Major facilitator Superfamily
B9N48_RS02005	COG0697	spore germination
B9N48_RS02010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B9N48_RS02020	COG2364	Membrane
B9N48_RS02025	COG1126	abc transporter atp-binding protein
B9N48_RS02030	COG0765	amino acid transport
B9N48_RS02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9N48_RS02040	COG0583	DNA-binding transcription factor activity
B9N48_RS02045	COG0163	prenyltransferase activity
B9N48_RS02050	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B9N48_RS02070	COG3104	oligopeptide transport
B9N48_RS02075	COG5434	Belongs to the glycosyl hydrolase 28 family
B9N48_RS02085	COG0697	spore germination
B9N48_RS02095	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B9N48_RS02100	COG1136	(ABC) transporter
B9N48_RS02105	COG0577	efflux transmembrane transporter activity
B9N48_RS02110	COG0745	RESPONSE REGULATOR receiver
B9N48_RS02115	COG5002	protein histidine kinase activity
B9N48_RS02115	COG3850	Histidine kinase
B9N48_RS02120	COG0457	Tetratricopeptide repeat
B9N48_RS02140	COG0527	aspartate kinase activity
B9N48_RS02145	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9N48_RS02150	COG4605	iron ion homeostasis
B9N48_RS02155	COG4604	ABC transporter, ATP-binding protein
B9N48_RS02160	COG4607	ABC-type enterochelin transport system periplasmic component
B9N48_RS02165	COG2814	Major facilitator Superfamily
B9N48_RS02170	COG1309	transcriptional regulator
B9N48_RS02175	COG0778	Nitroreductase
B9N48_RS02180	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B9N48_RS02185	COG0640	Transcriptional regulator
B9N48_RS02190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B9N48_RS02195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B9N48_RS02200	COG1012	belongs to the aldehyde dehydrogenase family
B9N48_RS02205	COG4975	Glucose uptake
B9N48_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS02215	COG4549	nuclear export factor GLE1
B9N48_RS02220	COG1276	copper resistance
B9N48_RS02220	COG2372	response to copper ion
B9N48_RS02225	COG1349	DNA-binding transcription factor activity
B9N48_RS02235	COG2213	PTS system mannitol-specific
B9N48_RS02240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9N48_RS02245	COG0246	Mannitol dehydrogenase
B9N48_RS02250	COG0473	3-isopropylmalate dehydrogenase activity
B9N48_RS02255	COG0681	Belongs to the peptidase S26 family
B9N48_RS02260	COG0412	Dienelactone hydrolase
B9N48_RS02265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B9N48_RS02275	COG0561	phosphatase activity
B9N48_RS02280	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B9N48_RS02285	COG1914	H( )-stimulated, divalent metal cation uptake system
B9N48_RS02290	COG4336	lyase activity
B9N48_RS02295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B9N48_RS02300	COG1984	allophanate hydrolase subunit 2
B9N48_RS02305	COG1414	Transcriptional regulator
B9N48_RS02310	COG2755	lipolytic protein G-D-S-L family
B9N48_RS02320	COG2329	Antibiotic biosynthesis monooxygenase
B9N48_RS02325	COG0768	penicillin binding
B9N48_RS02330	COG4989	oxidoreductase activity
B9N48_RS02335	COG3711	transcriptional antiterminator
B9N48_RS02340	COG0318	PFAM AMP-dependent synthetase and ligase
B9N48_RS02345	COG2226	methyltransferase
B9N48_RS02350	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS02355	COG1917	Cupin 2, conserved barrel domain protein
B9N48_RS02360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9N48_RS02365	COG3871	stress protein (general stress protein 26)
B9N48_RS02375	COG2814	Major facilitator Superfamily
B9N48_RS02380	COG1522	sequence-specific DNA binding
B9N48_RS02385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B9N48_RS02385	COG0551	DNA topoisomerase type I activity
B9N48_RS02390	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B9N48_RS02395	COG3706	GGDEF domain
B9N48_RS02400	COG5298	Protein conserved in bacteria
B9N48_RS02405	COG1215	transferase activity, transferring glycosyl groups
B9N48_RS02415	COG0531	amino acid
B9N48_RS02425	COG0028	Belongs to the TPP enzyme family
B9N48_RS02435	COG1914	H( )-stimulated, divalent metal cation uptake system
B9N48_RS02440	COG2261	transglycosylase associated protein
B9N48_RS02450	COG2217	Heavy metal translocating P-type atpase
B9N48_RS02455	COG3729	General stress protein
B9N48_RS02465	COG0662	Cupin 2, conserved barrel domain protein
B9N48_RS02470	COG2329	Antibiotic biosynthesis monooxygenase
B9N48_RS02475	COG3546	catalase activity
B9N48_RS02480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B9N48_RS02485	COG3290	protein histidine kinase activity
B9N48_RS02490	COG4565	transcriptional regulatory protein
B9N48_RS02495	COG1301	dicarboxylic acid transport
B9N48_RS02500	COG0628	permease
B9N48_RS02505	COG1131	(ABC) transporter
B9N48_RS02510	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B9N48_RS02520	COG1960	acyl-CoA dehydrogenase activity
B9N48_RS02535	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B9N48_RS02540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9N48_RS02545	COG1181	Belongs to the D-alanine--D-alanine ligase family
B9N48_RS02550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B9N48_RS02560	COG0513	Belongs to the DEAD box helicase family
B9N48_RS02565	COG3402	PFAM membrane-flanked domain
B9N48_RS02570	COG3428	Bacterial PH domain
B9N48_RS02580	COG0705	Rhomboid family
B9N48_RS02585	COG0736	holo-[acyl-carrier-protein] synthase activity
B9N48_RS02590	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B9N48_RS02595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B9N48_RS02600	COG0864	Transcriptional regulator
B9N48_RS02605	COG2337	Toxic component of a toxin-antitoxin (TA) module
B9N48_RS02610	COG1366	Belongs to the anti-sigma-factor antagonist family
B9N48_RS02615	COG1366	Belongs to the anti-sigma-factor antagonist family
B9N48_RS02620	COG2172	sigma factor antagonist activity
B9N48_RS02625	COG2208	phosphoserine phosphatase activity
B9N48_RS02630	COG1366	Belongs to the anti-sigma-factor antagonist family
B9N48_RS02635	COG2172	sigma factor antagonist activity
B9N48_RS02640	COG1191	sigma factor activity
B9N48_RS02645	COG2208	phosphoserine phosphatase activity
B9N48_RS02650	COG2183	response to ionizing radiation
B9N48_RS02660	COG3091	SprT-like family
B9N48_RS02715	COG1674	ftsk spoiiie
B9N48_RS02720	COG2946	Replication initiation factor
B9N48_RS02750	COG0433	COG0433 Predicted ATPase
B9N48_RS02760	COG5644	endopeptidase inhibitor activity
B9N48_RS02765	COG0741	lytic transglycosylase activity
B9N48_RS02765	COG0791	NLP P60 protein
B9N48_RS02790	COG1278	Cold shock
B9N48_RS02795	COG1329	Transcriptional regulator
B9N48_RS02805	COG0697	spore germination
B9N48_RS02810	COG1917	Cupin 2, conserved barrel domain protein
B9N48_RS02810	COG2207	Transcriptional regulator
B9N48_RS02815	COG0697	spore germination
B9N48_RS02820	COG3708	Transcriptional regulator
B9N48_RS02820	COG2207	Transcriptional regulator
B9N48_RS02825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B9N48_RS02830	COG0477	Major facilitator Superfamily
B9N48_RS02840	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
B9N48_RS02850	COG0697	spore germination
B9N48_RS02855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B9N48_RS02860	COG2030	dehydratase
B9N48_RS02865	COG3545	Serine hydrolase
B9N48_RS02870	COG1733	regulation of RNA biosynthetic process
B9N48_RS02875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B9N48_RS02880	COG1733	regulation of RNA biosynthetic process
B9N48_RS02885	COG2249	NAD(P)H dehydrogenase (quinone) activity
B9N48_RS02890	COG2814	Major facilitator Superfamily
B9N48_RS02895	COG1309	transcriptional regulator
B9N48_RS02900	COG0640	Transcriptional regulator
B9N48_RS02905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B9N48_RS02915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9N48_RS02920	COG0697	spore germination
B9N48_RS02925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B9N48_RS02930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B9N48_RS02935	COG0640	Transcriptional regulator
B9N48_RS02940	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B9N48_RS02955	COG4585	Histidine kinase
B9N48_RS02960	COG2197	response regulator
B9N48_RS02965	COG2409	Drug exporters of the RND superfamily
B9N48_RS02970	COG0596	Alpha beta hydrolase
B9N48_RS02975	COG1811	Na channel or pump
B9N48_RS02980	COG0789	Transcriptional regulator
B9N48_RS02980	COG4978	Transcriptional regulator
B9N48_RS02985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B9N48_RS02990	COG0778	Nitroreductase
B9N48_RS02995	COG0346	lactoylglutathione lyase activity
B9N48_RS03000	COG2259	Doxx family
B9N48_RS03005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9N48_RS03020	COG2323	membrane
B9N48_RS03025	COG2323	membrane
B9N48_RS03030	COG0071	Belongs to the small heat shock protein (HSP20) family
B9N48_RS03045	COG1309	transcriptional regulator
B9N48_RS03055	COG0456	acetyltransferase
B9N48_RS03060	COG0488	(ABC) transporter
B9N48_RS03065	COG1113	amino acid transport
B9N48_RS03070	COG2318	DinB family
B9N48_RS03075	COG1846	Transcriptional regulator
B9N48_RS03080	COG1033	growth of symbiont in host cell
B9N48_RS03080	COG2409	Drug exporters of the RND superfamily
B9N48_RS03085	COG0778	Nitroreductase
B9N48_RS03090	COG1846	Transcriptional regulator
B9N48_RS03095	COG2814	Major facilitator Superfamily
B9N48_RS03100	COG0730	response to heat
B9N48_RS03105	COG1802	Transcriptional regulator
B9N48_RS03110	COG1388	LysM domain
B9N48_RS03110	COG3858	chitin binding
B9N48_RS03115	COG1819	glycosyl
B9N48_RS03125	COG1785	Belongs to the alkaline phosphatase family
B9N48_RS03130	COG5646	InterPro IPR014922
B9N48_RS03140	COG0454	-acetyltransferase
B9N48_RS03145	COG1078	dGTPase activity
B9N48_RS03150	COG1388	LysM domain
B9N48_RS03155	COG2814	Major facilitator Superfamily
B9N48_RS03160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B9N48_RS03165	COG1447	Phosphotransferase system cellobiose-specific component IIA
B9N48_RS03170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B9N48_RS03175	COG2723	6-phospho-beta-galactosidase activity
B9N48_RS03180	COG2188	Transcriptional regulator
B9N48_RS03185	COG1940	carbohydrate kinase activity
B9N48_RS03190	COG1482	cell wall glycoprotein biosynthetic process
B9N48_RS03195	COG4124	Belongs to the glycosyl hydrolase 26 family
B9N48_RS03240	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B9N48_RS03245	COG0802	atpase or kinase
B9N48_RS03250	COG1214	PFAM Peptidase M22, glycoprotease
B9N48_RS03255	COG0456	acetyltransferase
B9N48_RS03260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B9N48_RS03265	COG0488	(ABC) transporter
B9N48_RS03270	COG0315	cyclic pyranopterin monophosphate synthase activity
B9N48_RS03275	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B9N48_RS03280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B9N48_RS03285	COG0805	protein transport
B9N48_RS03295	COG1266	CAAX protease self-immunity
B9N48_RS03305	COG0459	protein refolding
B9N48_RS03310	COG1073	alpha beta
B9N48_RS03315	COG0457	Tetratricopeptide repeat
B9N48_RS03320	COG1063	alcohol dehydrogenase
B9N48_RS03325	COG2211	Major facilitator Superfamily
B9N48_RS03330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9N48_RS03335	COG1842	Phage shock protein A
B9N48_RS03340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B9N48_RS03345	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B9N48_RS03350	COG4260	virion core protein, lumpy skin disease virus
B9N48_RS03360	COG2814	Major facilitator Superfamily
B9N48_RS03365	COG1063	alcohol dehydrogenase
B9N48_RS03370	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B9N48_RS03375	COG0823	Involved in the tonB-independent uptake of proteins
B9N48_RS03390	COG2267	carboxylic ester hydrolase activity
B9N48_RS03400	COG2132	Multicopper oxidase
B9N48_RS03405	COG1113	amino acid transport
B9N48_RS03415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B9N48_RS03420	COG0714	Associated with various cellular activities
B9N48_RS03425	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
B9N48_RS03430	COG1305	Transglutaminase-like
B9N48_RS03435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B9N48_RS03435	COG0519	Catalyzes the synthesis of GMP from XMP
B9N48_RS03440	COG2252	PERMEase
B9N48_RS03445	COG3064	Membrane
B9N48_RS03455	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
B9N48_RS03465	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B9N48_RS03470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B9N48_RS03475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B9N48_RS03480	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B9N48_RS03485	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B9N48_RS03490	COG0047	phosphoribosylformylglycinamidine synthase activity
B9N48_RS03495	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B9N48_RS03500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B9N48_RS03505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B9N48_RS03510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B9N48_RS03515	COG0138	bifunctional purine biosynthesis protein purh
B9N48_RS03520	COG0151	Belongs to the GarS family
B9N48_RS03525	COG1522	sequence-specific DNA binding
B9N48_RS03530	COG0531	amino acid
B9N48_RS03540	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B9N48_RS03545	COG1470	cell adhesion involved in biofilm formation
B9N48_RS03550	COG4496	protein, YerC YecD
B9N48_RS03555	COG0069	glutamate synthase activity
B9N48_RS03560	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
B9N48_RS03565	COG0210	DNA helicase
B9N48_RS03570	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B9N48_RS03575	COG4851	CamS sex pheromone cAM373 precursor
B9N48_RS03580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B9N48_RS03585	COG1285	pathogenesis
B9N48_RS03590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9N48_RS03595	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B9N48_RS03600	COG0154	amidase activity
B9N48_RS03605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B9N48_RS03615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B9N48_RS03620	COG1597	lipid kinase activity
B9N48_RS03625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B9N48_RS03640	COG3391	amine dehydrogenase activity
B9N48_RS03645	COG0457	Tetratricopeptide repeat
B9N48_RS03655	COG0217	transcriptional regulatory protein
B9N48_RS03665	COG1309	transcriptional regulator
B9N48_RS03670	COG3631	Ketosteroid isomerase-related protein
B9N48_RS03690	COG3546	catalase activity
B9N48_RS03695	COG0454	-acetyltransferase
B9N48_RS03705	COG5578	integral membrane protein
B9N48_RS03710	COG2972	Histidine kinase
B9N48_RS03715	COG4753	response regulator
B9N48_RS03715	COG2207	Transcriptional regulator
B9N48_RS03720	COG1653	transport
B9N48_RS03725	COG1175	transmembrane transport
B9N48_RS03730	COG0395	ABC-type sugar transport system, permease component
B9N48_RS03735	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B9N48_RS03740	COG2207	Transcriptional regulator
B9N48_RS03745	COG2755	lipolytic protein G-D-S-L family
B9N48_RS03755	COG5578	integral membrane protein
B9N48_RS03760	COG3401	FG-GAP repeat protein
B9N48_RS03765	COG3401	FG-GAP repeat protein
B9N48_RS03770	COG2755	lipolytic protein G-D-S-L family
B9N48_RS03775	COG1874	Beta-galactosidase
B9N48_RS03785	COG1653	transport
B9N48_RS03790	COG4209	transmembrane transport
B9N48_RS03795	COG0395	ABC-type sugar transport system, permease component
B9N48_RS03800	COG1486	melibiose metabolic process
B9N48_RS03805	COG2323	membrane
B9N48_RS03810	COG2329	Antibiotic biosynthesis monooxygenase
B9N48_RS03815	COG0346	lactoylglutathione lyase activity
B9N48_RS03830	COG5583	Uncharacterized small protein (DUF2292)
B9N48_RS03835	COG0670	Belongs to the BI1 family
B9N48_RS03850	COG2124	cytochrome p450
B9N48_RS03850	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B9N48_RS03860	COG1368	sulfuric ester hydrolase activity
B9N48_RS03865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B9N48_RS03870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9N48_RS03875	COG1442	glycosyl transferase family 8
B9N48_RS03880	COG1216	Glycosyl transferase, family 2
B9N48_RS03885	COG1442	glycosyl transferase family 8
B9N48_RS03890	COG2223	nitrite transmembrane transporter activity
B9N48_RS03895	COG1011	Hydrolase
B9N48_RS03900	COG0531	amino acid
B9N48_RS03905	COG1012	belongs to the aldehyde dehydrogenase family
B9N48_RS03910	COG0840	transmembrane signaling receptor activity
B9N48_RS03915	COG0488	(ABC) transporter
B9N48_RS03925	COG0789	Transcriptional regulator
B9N48_RS03930	COG2814	Major facilitator Superfamily
B9N48_RS03945	COG0488	(ABC) transporter
B9N48_RS03950	COG0513	Belongs to the DEAD box helicase family
B9N48_RS03955	COG0456	acetyltransferase
B9N48_RS03960	COG2130	NADP-dependent
B9N48_RS03970	COG1120	ATPase activity
B9N48_RS03975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9N48_RS03980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9N48_RS03985	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B9N48_RS04005	COG3866	Pectate lyase
B9N48_RS04010	COG0471	metal ion transport
B9N48_RS04015	COG3290	protein histidine kinase activity
B9N48_RS04020	COG4565	transcriptional regulatory protein
B9N48_RS04025	COG3181	Tripartite tricarboxylate transporter family receptor
B9N48_RS04030	COG2851	Citrate transporter
B9N48_RS04035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9N48_RS04040	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
B9N48_RS04045	COG1254	Belongs to the acylphosphatase family
B9N48_RS04050	COG2258	MOSC domain
B9N48_RS04070	COG0024	Methionine aminopeptidase
B9N48_RS04075	COG1263	PTS System
B9N48_RS04075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9N48_RS04080	COG1368	sulfuric ester hydrolase activity
B9N48_RS04095	COG1115	amino acid carrier protein
B9N48_RS04105	COG0697	spore germination
B9N48_RS04110	COG1263	PTS System
B9N48_RS04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9N48_RS04115	COG0366	Alpha amylase catalytic
B9N48_RS04120	COG2188	Transcriptional regulator
B9N48_RS04125	COG0778	Nitroreductase
B9N48_RS04130	COG0737	Belongs to the 5'-nucleotidase family
B9N48_RS04135	COG0693	protein deglycase activity
B9N48_RS04140	COG2814	Major facilitator Superfamily
B9N48_RS04145	COG4840	Belongs to the UPF0435 family
B9N48_RS04150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B9N48_RS04155	COG4980	gas vesicle protein
B9N48_RS04160	COG1295	ribonuclease BN
B9N48_RS04165	COG0477	Major facilitator Superfamily
B9N48_RS04170	COG0387	Pfam Sodium calcium exchanger
B9N48_RS04180	COG0668	transmembrane transport
B9N48_RS04185	COG0535	radical SAM domain protein
B9N48_RS04195	COG0726	polysaccharide deacetylase
B9N48_RS04200	COG2084	Dehydrogenase
B9N48_RS04205	COG0598	Magnesium transport protein CorA
B9N48_RS04210	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B9N48_RS04215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B9N48_RS04230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B9N48_RS04235	COG4637	Psort location Cytoplasmic, score
B9N48_RS04245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B9N48_RS04250	COG0022	dehydrogenase e1 component
B9N48_RS04255	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9N48_RS04260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B9N48_RS04265	COG3284	Transcriptional regulator
B9N48_RS04275	COG1742	UPF0060 membrane protein
B9N48_RS04300	COG4842	Belongs to the WXG100 family
B9N48_RS04305	COG1486	melibiose metabolic process
B9N48_RS04310	COG1737	Transcriptional regulator
B9N48_RS04315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9N48_RS04315	COG1263	PTS System
B9N48_RS04320	COG1132	(ABC) transporter
B9N48_RS04325	COG1132	(ABC) transporter
B9N48_RS04330	COG2259	Doxx family
B9N48_RS04335	COG2514	catechol 2,3-dioxygenase activity
B9N48_RS04340	COG0673	inositol 2-dehydrogenase activity
B9N48_RS04345	COG4585	Histidine kinase
B9N48_RS04350	COG2197	response regulator
B9N48_RS04355	COG1131	(ABC) transporter
B9N48_RS04360	COG1511	domain protein
B9N48_RS04360	COG0842	Transport permease protein
B9N48_RS04365	COG0842	Transport permease protein
B9N48_RS04370	COG1695	Transcriptional regulator
B9N48_RS04375	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
B9N48_RS04380	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
B9N48_RS04390	COG2318	DinB family
B9N48_RS04395	COG2814	Major facilitator Superfamily
B9N48_RS04400	COG1846	Transcriptional regulator
B9N48_RS04405	COG0392	lysyltransferase activity
B9N48_RS04405	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B9N48_RS04410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9N48_RS04415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9N48_RS04420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9N48_RS04425	COG0384	phenazine biosynthesis protein PhzF
B9N48_RS04430	COG0778	Nitroreductase
B9N48_RS04445	COG1090	epimerase
B9N48_RS04450	COG2137	regulation of response to DNA damage stimulus
B9N48_RS04460	COG2814	Major facilitator Superfamily
B9N48_RS04475	COG3103	Sh3 type 3 domain protein
B9N48_RS04480	COG5658	integral membrane protein
B9N48_RS04485	COG0596	Alpha beta hydrolase
B9N48_RS04490	COG0463	Glycosyl transferase, family 2
B9N48_RS04495	COG4485	Bacterial membrane protein, YfhO
B9N48_RS04500	COG1988	membrane-bound metal-dependent
B9N48_RS04505	COG1194	a g-specific adenine glycosylase
B9N48_RS04515	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS04530	COG3557	Belongs to the UPF0374 family
B9N48_RS04535	COG1132	(ABC) transporter
B9N48_RS04540	COG4129	membrane
B9N48_RS04545	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B9N48_RS04550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B9N48_RS04555	COG0735	belongs to the Fur family
B9N48_RS04665	COG4326	sporulation control protein
B9N48_RS04675	COG5577	PFAM Coat F domain
B9N48_RS04680	COG3340	Belongs to the peptidase S51 family
B9N48_RS04685	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B9N48_RS04690	COG0277	FAD linked oxidase domain protein
B9N48_RS04700	COG0753	catalase activity
B9N48_RS04705	COG1116	anion transmembrane transporter activity
B9N48_RS04710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B9N48_RS04715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B9N48_RS04720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9N48_RS04730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B9N48_RS04740	COG1476	TRANSCRIPTIONal
B9N48_RS04750	COG3382	B3 4 domain protein
B9N48_RS04755	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B9N48_RS04765	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B9N48_RS04770	COG0789	Transcriptional regulator
B9N48_RS04775	COG1664	Polymer-forming cytoskeletal
B9N48_RS04780	COG1664	Polymer-forming cytoskeletal
B9N48_RS04785	COG2766	serine protein kinase
B9N48_RS04790	COG2718	Belongs to the UPF0229 family
B9N48_RS04795	COG1846	Transcriptional regulator
B9N48_RS04800	COG1566	PFAM secretion protein HlyD family protein
B9N48_RS04805	COG2814	Major facilitator Superfamily
B9N48_RS04810	COG0655	NAD(P)H dehydrogenase (quinone) activity
B9N48_RS04830	COG1725	Transcriptional regulator
B9N48_RS04835	COG1131	(ABC) transporter
B9N48_RS04840	COG1131	(ABC) transporter
B9N48_RS04845	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B9N48_RS04850	COG1278	Cold shock
B9N48_RS04860	COG1464	Belongs to the NlpA lipoprotein family
B9N48_RS04865	COG3706	GGDEF domain
B9N48_RS04870	COG1823	symporter activity
B9N48_RS04890	COG5577	PFAM Coat F domain
B9N48_RS04895	COG4085	toxin activity
B9N48_RS04895	COG0737	Belongs to the 5'-nucleotidase family
B9N48_RS04895	COG1525	nuclease
B9N48_RS04900	COG3764	Sortase (surface protein transpeptidase)
B9N48_RS04905	COG0564	pseudouridine synthase activity
B9N48_RS04915	COG0517	IMP dehydrogenase activity
B9N48_RS04920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B9N48_RS04925	COG3153	acetyltransferase
B9N48_RS04925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B9N48_RS04930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B9N48_RS04935	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
B9N48_RS04940	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B9N48_RS04945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B9N48_RS04950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B9N48_RS04955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9N48_RS04960	COG2203	Gaf domain
B9N48_RS04960	COG4585	Histidine kinase
B9N48_RS04965	COG2197	response regulator
B9N48_RS04970	COG0431	NADPH-dependent FMN reductase
B9N48_RS04985	COG0791	NLP P60 protein
B9N48_RS04985	COG1388	LysM domain
B9N48_RS04990	COG1959	2 iron, 2 sulfur cluster binding
B9N48_RS04995	COG0668	transmembrane transport
B9N48_RS05000	COG2719	SpoVR family
B9N48_RS05005	COG1785	Belongs to the alkaline phosphatase family
B9N48_RS05010	COG1388	LysM domain
B9N48_RS05010	COG0791	NLP P60 protein
B9N48_RS05015	COG0583	DNA-binding transcription factor activity
B9N48_RS05020	COG0372	Belongs to the citrate synthase family
B9N48_RS05025	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS05030	COG0531	amino acid
B9N48_RS05035	COG0733	neurotransmitter:sodium symporter activity
B9N48_RS05040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B9N48_RS05045	COG0456	acetyltransferase
B9N48_RS05060	COG1595	DNA-templated transcription, initiation
B9N48_RS05065	COG0667	Aldo Keto reductase
B9N48_RS05070	COG0204	Acyl-transferase
B9N48_RS05075	COG1253	flavin adenine dinucleotide binding
B9N48_RS05080	COG0789	Transcriptional regulator
B9N48_RS05085	COG0436	Aminotransferase
B9N48_RS05090	COG1253	flavin adenine dinucleotide binding
B9N48_RS05095	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B9N48_RS05100	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B9N48_RS05105	COG0584	glycerophosphoryl diester phosphodiesterase
B9N48_RS05115	COG0668	transmembrane transport
B9N48_RS05120	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B9N48_RS05125	COG0726	polysaccharide deacetylase
B9N48_RS05130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B9N48_RS05135	COG1757	Na H antiporter
B9N48_RS05140	COG0589	response to stress
B9N48_RS05150	COG1132	(ABC) transporter
B9N48_RS05155	COG1132	(ABC) transporter
B9N48_RS05160	COG0702	epimerase
B9N48_RS05180	COG0189	ligase activity
B9N48_RS05185	COG0189	ligase activity
B9N48_RS05190	COG4399	Belongs to the UPF0754 family
B9N48_RS05195	COG3679	Belongs to the UPF0342 family
B9N48_RS05200	COG4335	DNA alkylation repair
B9N48_RS05205	COG0561	phosphatase activity
B9N48_RS05210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B9N48_RS05215	COG0475	glutathione-regulated potassium exporter activity
B9N48_RS05220	COG0490	domain, Protein
B9N48_RS05230	COG1024	Enoyl-CoA hydratase
B9N48_RS05240	COG4152	abc transporter atp-binding protein
B9N48_RS05245	COG1668	transmembrane transport
B9N48_RS05250	COG0420	3'-5' exonuclease activity
B9N48_RS05255	COG4717	serine-type aminopeptidase activity
B9N48_RS05260	COG3481	metal-dependent phosphohydrolase, HD sub domain
B9N48_RS05270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B9N48_RS05300	COG1846	Transcriptional regulator
B9N48_RS05305	COG4980	gas vesicle protein
B9N48_RS05320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B9N48_RS05325	COG0537	adenosine 5'-monophosphoramidase activity
B9N48_RS05330	COG1131	(ABC) transporter
B9N48_RS05335	COG4473	ABC transporter
B9N48_RS05345	COG1473	amidohydrolase
B9N48_RS05350	COG3069	C4-dicarboxylate transmembrane transporter activity
B9N48_RS05360	COG2329	Antibiotic biosynthesis monooxygenase
B9N48_RS05365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B9N48_RS05370	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B9N48_RS05375	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B9N48_RS05380	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B9N48_RS05385	COG1309	transcriptional regulator
B9N48_RS05390	COG1511	domain protein
B9N48_RS05395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B9N48_RS05400	COG4377	Putative membrane peptidase family (DUF2324)
B9N48_RS05410	COG1363	Peptidase, m42
B9N48_RS05415	COG4405	Protein conserved in bacteria
B9N48_RS05420	COG1301	dicarboxylic acid transport
B9N48_RS05430	COG1234	tRNA 3'-trailer cleavage
B9N48_RS05435	COG0095	Lipoate-protein ligase
B9N48_RS05440	COG0702	epimerase
B9N48_RS05445	COG0318	PFAM AMP-dependent synthetase and ligase
B9N48_RS05455	COG0501	Belongs to the peptidase M48B family
B9N48_RS05460	COG1404	Belongs to the peptidase S8 family
B9N48_RS05465	COG0456	acetyltransferase
B9N48_RS05470	COG0604	alcohol dehydrogenase
B9N48_RS05475	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B9N48_RS05480	COG0406	alpha-ribazole phosphatase activity
B9N48_RS05485	COG0183	Belongs to the thiolase family
B9N48_RS05490	COG0318	PFAM AMP-dependent synthetase and ligase
B9N48_RS05495	COG1268	BioY protein
B9N48_RS05500	COG0840	transmembrane signaling receptor activity
B9N48_RS05505	COG0723	plastoquinol--plastocyanin reductase activity
B9N48_RS05505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9N48_RS05510	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS05520	COG4903	ComK protein
B9N48_RS05525	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS05535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9N48_RS05550	COG0398	Pfam SNARE associated Golgi protein
B9N48_RS05555	COG0681	Belongs to the peptidase S26 family
B9N48_RS05560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B9N48_RS05565	COG1846	Transcriptional regulator
B9N48_RS05570	COG0738	Major facilitator superfamily
B9N48_RS05575	COG0673	inositol 2-dehydrogenase activity
B9N48_RS05580	COG0561	phosphatase activity
B9N48_RS05585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B9N48_RS05590	COG1609	Transcriptional regulator
B9N48_RS05595	COG3180	Ammonia monooxygenase
B9N48_RS05600	COG0477	Major facilitator Superfamily
B9N48_RS05600	COG2814	Major facilitator Superfamily
B9N48_RS05615	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
B9N48_RS05620	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
B9N48_RS05625	COG1074	ATP-dependent DNA helicase activity
B9N48_RS05630	COG0420	3'-5' exonuclease activity
B9N48_RS05635	COG0419	ATPase involved in DNA repair
B9N48_RS05640	COG1403	HNH endonuclease
B9N48_RS05680	COG5337	Spore coat protein CotH
B9N48_RS05685	COG0179	Fumarylacetoacetate (FAA) hydrolase
B9N48_RS05695	COG1404	Belongs to the peptidase S8 family
B9N48_RS05705	COG0367	asparagine synthase
B9N48_RS05710	COG1562	ergosterol biosynthetic process
B9N48_RS05715	COG0534	Mate efflux family protein
B9N48_RS05720	COG2207	Transcriptional regulator
B9N48_RS05720	COG1917	Cupin 2, conserved barrel domain protein
B9N48_RS05725	COG1609	Transcriptional regulator
B9N48_RS05730	COG0673	inositol 2-dehydrogenase activity
B9N48_RS05735	COG2318	DinB family
B9N48_RS05740	COG1279	arginine transmembrane transporter activity
B9N48_RS05745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B9N48_RS05750	COG1357	PFAM Pentapeptide repeats (8 copies)
B9N48_RS05755	COG2267	carboxylic ester hydrolase activity
B9N48_RS05760	COG0529	Catalyzes the synthesis of activated sulfate
B9N48_RS05765	COG2046	Belongs to the sulfate adenylyltransferase family
B9N48_RS05770	COG0175	sulfate reduction
B9N48_RS05775	COG2045	Belongs to the ComB family
B9N48_RS05780	COG1809	phosphosulfolactate synthase activity
B9N48_RS05785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B9N48_RS05790	COG4948	Mandelate Racemase Muconate Lactonizing
B9N48_RS05795	COG2814	Major facilitator Superfamily
B9N48_RS05800	COG0454	-acetyltransferase
B9N48_RS05810	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B9N48_RS05810	COG0646	methionine synthase
B9N48_RS05815	COG1666	GTP binding
B9N48_RS05820	COG2996	Protein conserved in bacteria
B9N48_RS05840	COG1695	Transcriptional regulator
B9N48_RS05855	COG3227	Zinc metalloprotease (Elastase)
B9N48_RS05860	COG1307	EDD domain protein, DegV family
B9N48_RS05865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B9N48_RS05880	COG0561	phosphatase activity
B9N48_RS05885	COG1073	alpha beta
B9N48_RS05890	COG2151	metal-sulfur cluster biosynthetic enzyme
B9N48_RS05900	COG0277	FAD linked oxidase domain protein
B9N48_RS05905	COG2271	Major facilitator Superfamily
B9N48_RS05910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B9N48_RS05915	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B9N48_RS05925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B9N48_RS05930	COG0505	Belongs to the CarA family
B9N48_RS05935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B9N48_RS05940	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B9N48_RS05955	COG2267	carboxylic ester hydrolase activity
B9N48_RS05965	COG1744	ABC transporter substrate-binding protein PnrA-like
B9N48_RS05980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B9N48_RS05985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B9N48_RS05990	COG5504	Zn-dependent protease
B9N48_RS05995	COG0444	Belongs to the ABC transporter superfamily
B9N48_RS06000	COG4608	Belongs to the ABC transporter superfamily
B9N48_RS06010	COG0601	transmembrane transport
B9N48_RS06015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9N48_RS06025	COG0180	Tryptophanyl-tRNA synthetase
B9N48_RS06030	COG4166	transmembrane transport
B9N48_RS06035	COG0601	transmembrane transport
B9N48_RS06040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9N48_RS06045	COG0444	Belongs to the ABC transporter superfamily
B9N48_RS06050	COG4608	Belongs to the ABC transporter superfamily
B9N48_RS06055	COG2814	Major facilitator Superfamily
B9N48_RS06060	COG0456	acetyltransferase
B9N48_RS06065	COG1393	Belongs to the ArsC family
B9N48_RS06070	COG0861	Integral membrane protein TerC family
B9N48_RS06075	COG4862	establishment of competence for transformation
B9N48_RS06080	COG4469	Competence protein
B9N48_RS06085	COG1164	Oligoendopeptidase f
B9N48_RS06100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B9N48_RS06105	COG2346	COG2346, Truncated hemoglobins
B9N48_RS06110	COG0741	lytic transglycosylase activity
B9N48_RS06115	COG4116	CYTH
B9N48_RS06125	COG2357	RelA SpoT domain protein
B9N48_RS06130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B9N48_RS06135	COG0564	pseudouridine synthase activity
B9N48_RS06140	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B9N48_RS06145	COG0569	domain protein
B9N48_RS06145	COG0475	glutathione-regulated potassium exporter activity
B9N48_RS06150	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B9N48_RS06155	COG0352	thiamine-phosphate diphosphorylase activity
B9N48_RS06160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9N48_RS06165	COG2104	thiamine diphosphate biosynthetic process
B9N48_RS06170	COG2022	thiamine diphosphate biosynthetic process
B9N48_RS06175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B9N48_RS06180	COG0351	phosphomethylpyrimidine kinase
B9N48_RS06185	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B9N48_RS06240	COG0210	DNA helicase
B9N48_RS06250	COG2153	protein acetylation
B9N48_RS06255	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B9N48_RS06260	COG2382	esterase
B9N48_RS06265	COG0626	cystathionine gamma-synthase activity
B9N48_RS06270	COG0626	cystathionine gamma-synthase activity
B9N48_RS06275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9N48_RS06280	COG5505	Protein of unknown function (DUF819)
B9N48_RS06290	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B9N48_RS06295	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS06305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9N48_RS06305	COG3711	transcriptional antiterminator
B9N48_RS06310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9N48_RS06310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9N48_RS06310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9N48_RS06315	COG1482	cell wall glycoprotein biosynthetic process
B9N48_RS06325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9N48_RS06335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B9N48_RS06355	COG0109	protoheme IX farnesyltransferase activity
B9N48_RS06365	COG0726	polysaccharide deacetylase
B9N48_RS06380	COG5504	Zn-dependent protease
B9N48_RS06385	COG2205	protein histidine kinase activity
B9N48_RS06395	COG3383	formate dehydrogenase (NAD+) activity
B9N48_RS06400	COG2427	Protein of unknown function (DUF1641)
B9N48_RS06410	COG1051	belongs to the nudix hydrolase family
B9N48_RS06420	COG2124	cytochrome p450
B9N48_RS06425	COG1819	glycosyl
B9N48_RS06435	COG1587	Uroporphyrinogen-III synthase
B9N48_RS06440	COG0390	transport system, permease component
B9N48_RS06445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B9N48_RS06455	COG4297	protein containing double-stranded beta helix domain
B9N48_RS06465	COG1252	NADH dehydrogenase
B9N48_RS06470	COG1904	glucuronate isomerase
B9N48_RS06475	COG2211	Major facilitator Superfamily
B9N48_RS06480	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B9N48_RS06485	COG1063	alcohol dehydrogenase
B9N48_RS06490	COG1312	Catalyzes the dehydration of D-mannonate
B9N48_RS06495	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS06500	COG2271	Major facilitator Superfamily
B9N48_RS06505	COG1609	Transcriptional regulator
B9N48_RS06510	COG0246	Mannitol dehydrogenase
B9N48_RS06515	COG2721	sulfolactate sulfo-lyase activity
B9N48_RS06520	COG0730	response to heat
B9N48_RS06525	COG2318	DinB family
B9N48_RS06530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B9N48_RS06535	COG0457	Tetratricopeptide repeat
B9N48_RS06545	COG2350	Protein conserved in bacteria
B9N48_RS06550	COG5632	N-Acetylmuramoyl-L-alanine amidase
B9N48_RS06550	COG3409	Peptidoglycan-binding domain 1 protein
B9N48_RS06550	COG1388	LysM domain
B9N48_RS06560	COG4195	phage-related replication protein
B9N48_RS06565	COG3546	catalase activity
B9N48_RS06570	COG2856	Zn peptidase
B9N48_RS06575	COG1396	sequence-specific DNA binding
B9N48_RS06585	COG1522	sequence-specific DNA binding
B9N48_RS06590	COG1484	DNA-dependent DNA replication
B9N48_RS06610	COG1595	DNA-templated transcription, initiation
B9N48_RS06615	COG5484	DNA packaging
B9N48_RS06615	COG3728	DNA packaging
B9N48_RS06620	COG1783	phage Terminase large subunit
B9N48_RS06625	COG5518	Phage portal protein
B9N48_RS06630	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B9N48_RS06635	COG4653	Phage capsid family
B9N48_RS06680	COG5412	phage tail tape measure protein
B9N48_RS06680	COG3953	SLT domain
B9N48_RS06685	COG4193	domain, Protein
B9N48_RS06695	COG3628	GPW Gp25 family protein
B9N48_RS06700	COG3299	homolog of phage Mu protein gp47
B9N48_RS06705	COG3778	Protein conserved in bacteria
B9N48_RS06745	COG5632	N-Acetylmuramoyl-L-alanine amidase
B9N48_RS06745	COG3409	Peptidoglycan-binding domain 1 protein
B9N48_RS06760	COG0306	phosphate transporter
B9N48_RS06765	COG1392	Phosphate transport regulator
B9N48_RS06770	COG0531	amino acid
B9N48_RS06775	COG0346	lactoylglutathione lyase activity
B9N48_RS06780	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B9N48_RS06785	COG0463	Glycosyl transferase, family 2
B9N48_RS06790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9N48_RS06795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B9N48_RS06800	COG2362	D-Aminopeptidase
B9N48_RS06805	COG0601	transmembrane transport
B9N48_RS06810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9N48_RS06815	COG0444	Belongs to the ABC transporter superfamily
B9N48_RS06820	COG4166	transmembrane transport
B9N48_RS06825	COG1619	proteins homologs of microcin C7 resistance protein MccF
B9N48_RS06830	COG4948	Mandelate Racemase Muconate Lactonizing
B9N48_RS06835	COG0791	NLP P60 protein
B9N48_RS06840	COG4608	Belongs to the ABC transporter superfamily
B9N48_RS06845	COG2706	6-phosphogluconolactonase activity
B9N48_RS06850	COG1834	amidinotransferase
B9N48_RS06855	COG1607	acyl-coa hydrolase
B9N48_RS06860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B9N48_RS06860	COG1017	nitric oxide dioxygenase activity
B9N48_RS06870	COG2323	membrane
B9N48_RS06875	COG2318	DinB family
B9N48_RS06880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9N48_RS06885	COG2076	Multidrug Resistance protein
B9N48_RS06890	COG2076	Multidrug Resistance protein
B9N48_RS06895	COG0788	formyltetrahydrofolate deformylase activity
B9N48_RS06900	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B9N48_RS06905	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B9N48_RS06910	COG1764	response to oxidative stress
B9N48_RS06915	COG1846	Transcriptional regulator
B9N48_RS06920	COG1764	response to oxidative stress
B9N48_RS06930	COG0590	tRNA wobble adenosine to inosine editing
B9N48_RS06935	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B9N48_RS06940	COG1404	Belongs to the peptidase S8 family
B9N48_RS06945	COG1366	Belongs to the anti-sigma-factor antagonist family
B9N48_RS06950	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B9N48_RS06955	COG1122	ATPase activity
B9N48_RS06960	COG4721	ABC-type cobalt transport system, permease component
B9N48_RS06970	COG0745	RESPONSE REGULATOR receiver
B9N48_RS06975	COG3850	Histidine kinase
B9N48_RS06975	COG5002	protein histidine kinase activity
B9N48_RS06980	COG3212	peptidase
B9N48_RS06985	COG3212	peptidase
B9N48_RS07000	COG2239	Acts as a magnesium transporter
B9N48_RS07005	COG0789	Transcriptional regulator
B9N48_RS07020	COG1846	Transcriptional regulator
B9N48_RS07030	COG0726	polysaccharide deacetylase
B9N48_RS07035	COG1408	metallophosphoesterase
B9N48_RS07045	COG0463	Glycosyl transferase, family 2
B9N48_RS07050	COG1793	dna ligase
B9N48_RS07050	COG3285	dna ligase
B9N48_RS07055	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B9N48_RS07060	COG3300	MHYT domain
B9N48_RS07060	COG5001	Diguanylate cyclase
B9N48_RS07065	COG0586	Pfam SNARE associated Golgi protein
B9N48_RS07070	COG0861	Integral membrane protein TerC family
B9N48_RS07075	COG1191	sigma factor activity
B9N48_RS07095	COG0501	Belongs to the peptidase M48B family
B9N48_RS07100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B9N48_RS07115	COG3594	Acyltransferase
B9N48_RS07120	COG5002	protein histidine kinase activity
B9N48_RS07125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B9N48_RS07130	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B9N48_RS07135	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
B9N48_RS07140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B9N48_RS07145	COG0436	Aminotransferase
B9N48_RS07150	COG1850	ribulose-bisphosphate carboxylase activity
B9N48_RS07155	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
B9N48_RS07160	COG0235	Class ii aldolase
B9N48_RS07165	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B9N48_RS07170	COG3339	Conserved Protein
B9N48_RS07185	COG3852	Histidine kinase
B9N48_RS07190	COG1846	Transcriptional regulator
B9N48_RS07195	COG1360	Flagellar Motor Protein
B9N48_RS07200	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B9N48_RS07205	COG0542	response to heat
B9N48_RS07210	COG3949	Membrane
B9N48_RS07215	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B9N48_RS07220	COG0720	synthase
B9N48_RS07225	COG0602	queuosine metabolic process
B9N48_RS07230	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B9N48_RS07235	COG1733	regulation of RNA biosynthetic process
B9N48_RS07240	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS07245	COG4641	Protein conserved in bacteria
B9N48_RS07245	COG1388	LysM domain
B9N48_RS07250	COG1388	LysM domain
B9N48_RS07255	COG3858	chitin binding
B9N48_RS07260	COG3858	chitin binding
B9N48_RS07270	COG4873	Protein conserved in bacteria
B9N48_RS07280	COG3773	Cell wall hydrolase
B9N48_RS07285	COG2244	polysaccharide biosynthetic process
B9N48_RS07290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9N48_RS07295	COG2217	Heavy metal translocating P-type atpase
B9N48_RS07305	COG0006	proline dipeptidase activity
B9N48_RS07310	COG1609	Transcriptional regulator
B9N48_RS07315	COG3711	transcriptional antiterminator
B9N48_RS07320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9N48_RS07320	COG1263	PTS System
B9N48_RS07320	COG2190	(PTS) system
B9N48_RS07325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9N48_RS07330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B9N48_RS07340	COG1533	DNA photolyase activity
B9N48_RS07345	COG0456	acetyltransferase
B9N48_RS07350	COG0840	transmembrane signaling receptor activity
B9N48_RS07355	COG2084	Dehydrogenase
B9N48_RS07360	COG2340	Cysteine-rich secretory protein family
B9N48_RS07370	COG4191	Histidine kinase
B9N48_RS07375	COG0436	Aminotransferase
B9N48_RS07385	COG0784	Response regulator, receiver
B9N48_RS07385	COG0835	chemotaxis
B9N48_RS07395	COG2814	Major facilitator Superfamily
B9N48_RS07400	COG1376	ErfK ybiS ycfS ynhG family protein
B9N48_RS07405	COG1408	metallophosphoesterase
B9N48_RS07410	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS07415	COG2200	EAL domain
B9N48_RS07420	COG4703	Protein of unknown function (DUF1797)
B9N48_RS07425	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
B9N48_RS07435	COG0517	IMP dehydrogenase activity
B9N48_RS07440	COG0583	DNA-binding transcription factor activity
B9N48_RS07445	COG0716	FMN binding
B9N48_RS07455	COG0716	FMN binding
B9N48_RS07460	COG2171	N-acyltransferase activity
B9N48_RS07465	COG1473	amidohydrolase
B9N48_RS07475	COG0668	transmembrane transport
B9N48_RS07480	COG0450	alkyl hydroperoxide reductase
B9N48_RS07485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9N48_RS07500	COG0746	molybdenum cofactor guanylyltransferase activity
B9N48_RS07505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B9N48_RS07510	COG0303	'Molybdopterin
B9N48_RS07515	COG1763	Mo-molybdopterin cofactor biosynthetic process
B9N48_RS07520	COG0314	molybdopterin synthase activity
B9N48_RS07525	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B9N48_RS07530	COG1132	(ABC) transporter
B9N48_RS07535	COG1132	(ABC) transporter
B9N48_RS07545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9N48_RS07550	COG1136	(ABC) transporter
B9N48_RS07555	COG0577	efflux transmembrane transporter activity
B9N48_RS07560	COG1349	DNA-binding transcription factor activity
B9N48_RS07565	COG1105	Belongs to the carbohydrate kinase PfkB family
B9N48_RS07570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9N48_RS07570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B9N48_RS07570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9N48_RS07575	COG0681	Belongs to the peptidase S26 family
B9N48_RS07585	COG0488	(ABC) transporter
B9N48_RS07590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B9N48_RS07595	COG2309	aminopeptidase activity
B9N48_RS07605	COG1077	Cell shape determining protein MreB Mrl
B9N48_RS07610	COG2002	toxin-antitoxin pair type II binding
B9N48_RS07615	COG3852	Histidine kinase
B9N48_RS07620	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
B9N48_RS07620	COG2105	PFAM AIG2 family protein
B9N48_RS07625	COG0569	domain protein
B9N48_RS07630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B9N48_RS07635	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B9N48_RS07640	COG5503	Protein of unknown function (DUF1447)
B9N48_RS07645	COG0561	phosphatase activity
B9N48_RS07650	COG0242	peptide deformylase activity
B9N48_RS07660	COG0497	DNA recombination
B9N48_RS07665	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B9N48_RS07670	COG0022	dehydrogenase e1 component
B9N48_RS07675	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9N48_RS07680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B9N48_RS07685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9N48_RS07695	COG1982	Orn Lys Arg decarboxylase major
B9N48_RS07700	COG4476	Belongs to the UPF0223 family
B9N48_RS07705	COG4493	Belongs to the UPF0637 family
B9N48_RS07715	COG0483	inositol monophosphate 1-phosphatase activity
B9N48_RS07725	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B9N48_RS07745	COG1595	DNA-templated transcription, initiation
B9N48_RS07765	COG1217	gtp-binding protein TYPA
B9N48_RS07775	COG4896	Protein conserved in bacteria
B9N48_RS07785	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B9N48_RS07790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B9N48_RS07795	COG2066	Belongs to the glutaminase family
B9N48_RS07800	COG4838	Belongs to the UPF0358 family
B9N48_RS07805	COG0772	Belongs to the SEDS family
B9N48_RS07810	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B9N48_RS07815	COG1612	heme a metabolic process
B9N48_RS07820	COG0109	protoheme IX farnesyltransferase activity
B9N48_RS07825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B9N48_RS07825	COG2010	Cytochrome c
B9N48_RS07830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B9N48_RS07835	COG1845	cytochrome c oxidase, subunit III
B9N48_RS07840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B9N48_RS07845	COG3336	cytochrome c oxidase
B9N48_RS07855	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
B9N48_RS07860	COG2340	Cysteine-rich secretory protein family
B9N48_RS07875	COG3679	Belongs to the UPF0342 family
B9N48_RS07880	COG4471	UPF0298 protein
B9N48_RS07885	COG0742	ribosomal rna small subunit methyltransferase
B9N48_RS07890	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B9N48_RS07895	COG3314	Sporulation integral membrane protein YlbJ
B9N48_RS07900	COG1752	Esterase of the alpha-beta hydrolase superfamily
B9N48_RS07905	COG3480	Lon protease (S16) C-terminal proteolytic domain
B9N48_RS07910	COG1323	Belongs to the UPF0348 family
B9N48_RS07920	COG1399	metal-binding, possibly nucleic acid-binding protein
B9N48_RS07935	COG0454	-acetyltransferase
B9N48_RS07940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B9N48_RS07945	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
B9N48_RS07950	COG2001	Belongs to the MraZ family
B9N48_RS07955	COG0275	rRNA processing
B9N48_RS07960	COG4839	cell division protein FtsL
B9N48_RS07970	COG0768	penicillin binding
B9N48_RS07975	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B9N48_RS07980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B9N48_RS07985	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B9N48_RS07990	COG0772	Belongs to the SEDS family
B9N48_RS07995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B9N48_RS08000	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B9N48_RS08005	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B9N48_RS08010	COG3879	Bacterial protein of unknown function (DUF881)
B9N48_RS08015	COG3879	Bacterial protein of unknown function (DUF881)
B9N48_RS08020	COG3856	small basic protein
B9N48_RS08025	COG0849	cell division
B9N48_RS08030	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B9N48_RS08035	COG4412	M6 family metalloprotease domain protein
B9N48_RS08035	COG1404	Belongs to the peptidase S8 family
B9N48_RS08045	COG1191	sigma factor activity
B9N48_RS08050	COG1191	sigma factor activity
B9N48_RS08055	COG1119	ATPase activity
B9N48_RS08060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9N48_RS08065	COG1873	PFAM PRC-barrel domain
B9N48_RS08070	COG1496	oxidoreductase activity
B9N48_RS08075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B9N48_RS08080	COG1799	cell septum assembly
B9N48_RS08085	COG0762	integral membrane protein
B9N48_RS08090	COG2302	S4 RNA-binding domain
B9N48_RS08095	COG3599	regulation of cell shape
B9N48_RS08100	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B9N48_RS08105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B9N48_RS08110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B9N48_RS08115	COG0564	pseudouridine synthase activity
B9N48_RS08120	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B9N48_RS08125	COG2233	PERMEase
B9N48_RS08130	COG0540	Belongs to the ATCase OTCase family
B9N48_RS08135	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B9N48_RS08140	COG0505	Belongs to the CarA family
B9N48_RS08145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B9N48_RS08150	COG0543	2 iron, 2 sulfur cluster binding
B9N48_RS08155	COG0167	dihydroorotate dehydrogenase activity
B9N48_RS08160	COG0284	orotidine-5'-phosphate decarboxylase activity
B9N48_RS08165	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B9N48_RS08170	COG0175	sulfate reduction
B9N48_RS08175	COG0306	phosphate transporter
B9N48_RS08180	COG2046	Belongs to the sulfate adenylyltransferase family
B9N48_RS08185	COG0529	Catalyzes the synthesis of activated sulfate
B9N48_RS08190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B9N48_RS08195	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
B9N48_RS08200	COG1648	precorrin-2 dehydrogenase activity
B9N48_RS08205	COG1293	RNA-binding protein homologous to eukaryotic snRNP
B9N48_RS08210	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B9N48_RS08215	COG1561	YicC-like family, N-terminal region
B9N48_RS08225	COG0194	GDP metabolic process
B9N48_RS08230	COG1758	RNA polymerase activity
B9N48_RS08235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B9N48_RS08240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B9N48_RS08245	COG0242	peptide deformylase activity
B9N48_RS08250	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B9N48_RS08255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B9N48_RS08255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B9N48_RS08260	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B9N48_RS08265	COG0631	protein serine/threonine phosphatase activity
B9N48_RS08270	COG0515	serine threonine protein kinase
B9N48_RS08270	COG2815	serine threonine protein kinase
B9N48_RS08275	COG1162	GTPase activity
B9N48_RS08280	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B9N48_RS08285	COG1564	THIamine pyrophosphokinase
B9N48_RS08295	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B9N48_RS08300	COG1302	Protein conserved in bacteria
B9N48_RS08305	COG1461	Dihydroxyacetone kinase
B9N48_RS08310	COG1760	l-serine dehydratase
B9N48_RS08315	COG1760	l-serine dehydratase
B9N48_RS08320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B9N48_RS08325	COG2050	protein possibly involved in aromatic compounds catabolism
B9N48_RS08325	COG1349	DNA-binding transcription factor activity
B9N48_RS08330	COG0416	fatty acid biosynthetic process
B9N48_RS08335	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B9N48_RS08340	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS08350	COG0571	ribonuclease III activity
B9N48_RS08355	COG1196	nuclear chromosome segregation
B9N48_RS08360	COG0552	protein localization to endoplasmic reticulum
B9N48_RS08370	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
B9N48_RS08375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B9N48_RS08380	COG0228	four-way junction DNA binding
B9N48_RS08385	COG1837	Belongs to the UPF0109 family
B9N48_RS08395	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B9N48_RS08400	COG0336	Belongs to the RNA methyltransferase TrmD family
B9N48_RS08405	COG0335	large ribosomal subunit rRNA binding
B9N48_RS08410	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B9N48_RS08415	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B9N48_RS08425	COG2257	FlhB HrpN YscU SpaS Family
B9N48_RS08430	COG0045	succinate-CoA ligase (ADP-forming) activity
B9N48_RS08435	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B9N48_RS08440	COG0758	DNA mediated transformation
B9N48_RS08445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B9N48_RS08450	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B9N48_RS08455	COG4974	Belongs to the 'phage' integrase family
B9N48_RS08460	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B9N48_RS08465	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B9N48_RS08470	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B9N48_RS08475	COG1815	bacterial-type flagellum-dependent cell motility
B9N48_RS08480	COG1558	bacterial-type flagellum-dependent cell motility
B9N48_RS08485	COG1677	Flagellar hook-basal body complex protein FliE
B9N48_RS08490	COG1766	The M ring may be actively involved in energy transduction
B9N48_RS08495	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B9N48_RS08500	COG1317	bacterial-type flagellum organization
B9N48_RS08505	COG1157	protein secretion by the type III secretion system
B9N48_RS08510	COG2882	bacterial-type flagellum organization
B9N48_RS08515	COG3334	PFAM MgtE intracellular
B9N48_RS08520	COG3144	bacterial-type flagellum assembly
B9N48_RS08525	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B9N48_RS08530	COG4786	Flagellar basal body rod
B9N48_RS08535	COG1582	Flagellar protein (FlbD)
B9N48_RS08540	COG1580	Controls the rotational direction of flagella during chemotaxis
B9N48_RS08545	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B9N48_RS08550	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B9N48_RS08550	COG1776	CheC inhibitor of MCP methylation
B9N48_RS08555	COG2201	protein-glutamate methylesterase activity
B9N48_RS08560	COG3190	flagellar
B9N48_RS08565	COG1338	Plays a role in the flagellum-specific transport system
B9N48_RS08570	COG1987	bacterial-type flagellum assembly
B9N48_RS08575	COG1684	flagellar biosynthetic protein fliR
B9N48_RS08580	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B9N48_RS08585	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B9N48_RS08590	COG1419	protein localization to endoplasmic reticulum
B9N48_RS08595	COG0455	bacterial-type flagellum organization
B9N48_RS08600	COG2201	protein-glutamate methylesterase activity
B9N48_RS08605	COG2198	Histidine kinase
B9N48_RS08605	COG0643	Histidine kinase
B9N48_RS08610	COG0835	chemotaxis
B9N48_RS08615	COG1776	CheC inhibitor of MCP methylation
B9N48_RS08620	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
B9N48_RS08625	COG1191	sigma factor activity
B9N48_RS08635	COG0052	Belongs to the universal ribosomal protein uS2 family
B9N48_RS08640	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B9N48_RS08645	COG0528	UMP kinase activity
B9N48_RS08650	COG0233	cytoplasmic translational termination
B9N48_RS08655	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B9N48_RS08660	COG4589	Belongs to the CDS family
B9N48_RS08665	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B9N48_RS08670	COG0750	zinc metalloprotease
B9N48_RS08675	COG0442	prolyl-tRNA aminoacylation
B9N48_RS08680	COG2176	DNA-directed DNA polymerase activity
B9N48_RS08685	COG0779	Required for maturation of 30S ribosomal subunits
B9N48_RS08690	COG0195	Participates in both transcription termination and antitermination
B9N48_RS08695	COG2740	Nucleic-acid-binding protein implicated in transcription termination
B9N48_RS08700	COG1358	cellular component organization or biogenesis
B9N48_RS08705	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B9N48_RS08710	COG1550	Protein conserved in bacteria
B9N48_RS08715	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B9N48_RS08720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B9N48_RS08725	COG0196	riboflavin kinase activity
B9N48_RS08730	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B9N48_RS08735	COG1185	polyribonucleotide nucleotidyltransferase activity
B9N48_RS08740	COG0726	polysaccharide deacetylase
B9N48_RS08745	COG0612	Peptidase, M16
B9N48_RS08750	COG1873	PFAM PRC-barrel domain
B9N48_RS08755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B9N48_RS08760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B9N48_RS08765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B9N48_RS08770	COG0527	aspartate kinase activity
B9N48_RS08775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B9N48_RS08780	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B9N48_RS08785	COG0740	serine-type endopeptidase activity
B9N48_RS08795	COG1674	ftsk spoiiie
B9N48_RS08795	COG4980	gas vesicle protein
B9N48_RS08800	COG2188	Transcriptional regulator
B9N48_RS08805	COG2814	Major facilitator Superfamily
B9N48_RS08810	COG0612	Peptidase, M16
B9N48_RS08815	COG0612	Peptidase, M16
B9N48_RS08820	COG0300	oxidoreductase activity
B9N48_RS08835	COG1426	Protein conserved in bacteria
B9N48_RS08840	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B9N48_RS08845	COG1546	Belongs to the CinA family
B9N48_RS08845	COG1058	Belongs to the CinA family
B9N48_RS08850	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B9N48_RS08855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B9N48_RS08860	COG1418	mRNA catabolic process
B9N48_RS08865	COG1692	metallophosphoesterase
B9N48_RS08870	COG2359	stage V sporulation protein S
B9N48_RS08875	COG1063	alcohol dehydrogenase
B9N48_RS08880	COG0156	8-amino-7-oxononanoate synthase activity
B9N48_RS08885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B9N48_RS08890	COG4550	Control of competence regulator ComK, YlbF/YmcA
B9N48_RS08900	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B9N48_RS08905	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B9N48_RS08920	COG3226	Transcriptional regulator
B9N48_RS08925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9N48_RS08935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B9N48_RS08940	COG3321	synthase
B9N48_RS08945	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B9N48_RS08945	COG2070	2-Nitropropane dioxygenase
B9N48_RS08950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B9N48_RS08955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B9N48_RS08960	COG3425	synthase
B9N48_RS08965	COG1024	Enoyl-CoA hydratase
B9N48_RS08970	COG1024	Enoyl-CoA hydratase
B9N48_RS08975	COG0318	PFAM AMP-dependent synthetase and ligase
B9N48_RS08975	COG3321	synthase
B9N48_RS08975	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS08975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9N48_RS08975	COG0300	oxidoreductase activity
B9N48_RS08980	COG3321	synthase
B9N48_RS08980	COG0300	oxidoreductase activity
B9N48_RS08980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B9N48_RS08980	COG4221	oxidoreductase activity
B9N48_RS08990	COG4221	oxidoreductase activity
B9N48_RS08990	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS08990	COG3321	synthase
B9N48_RS08990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9N48_RS08995	COG3321	synthase
B9N48_RS08995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B9N48_RS08995	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B9N48_RS08995	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B9N48_RS09000	COG2124	cytochrome p450
B9N48_RS09010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9N48_RS09015	COG1404	Belongs to the peptidase S8 family
B9N48_RS09025	COG4195	phage-related replication protein
B9N48_RS09030	COG1764	response to oxidative stress
B9N48_RS09035	COG2076	Multidrug Resistance protein
B9N48_RS09040	COG2076	Multidrug Resistance protein
B9N48_RS09055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B9N48_RS09060	COG1923	regulation of RNA biosynthetic process
B9N48_RS09075	COG1780	Probably involved in ribonucleotide reductase function
B9N48_RS09080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9N48_RS09085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9N48_RS09090	COG4112	unkown
B9N48_RS09095	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9N48_RS09105	COG0464	growth
B9N48_RS09110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B9N48_RS09115	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
B9N48_RS09120	COG0789	Transcriptional regulator
B9N48_RS09125	COG0174	glutamine synthetase
B9N48_RS09145	COG4282	regulation of fungal-type cell wall biogenesis
B9N48_RS09155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9N48_RS09175	COG0135	phosphoribosylanthranilate isomerase activity
B9N48_RS09180	COG2211	Major facilitator Superfamily
B9N48_RS09185	COG3507	Belongs to the glycosyl hydrolase 43 family
B9N48_RS09190	COG1940	carbohydrate kinase activity
B9N48_RS09195	COG2115	Belongs to the xylose isomerase family
B9N48_RS09200	COG1070	Carbohydrate kinase
B9N48_RS09210	COG1525	nuclease
B9N48_RS09215	COG2814	Major facilitator Superfamily
B9N48_RS09220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B9N48_RS09230	COG0756	dUTP diphosphatase activity
B9N48_RS09245	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B9N48_RS09270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B9N48_RS09280	COG3832	glyoxalase III activity
B9N48_RS09295	COG0697	spore germination
B9N48_RS09300	COG0531	amino acid
B9N48_RS09330	COG4195	phage-related replication protein
B9N48_RS09340	COG0346	lactoylglutathione lyase activity
B9N48_RS09350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B9N48_RS09355	COG1388	LysM domain
B9N48_RS09360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B9N48_RS09365	COG4224	UPF0291 protein
B9N48_RS09370	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B9N48_RS09380	COG3763	UPF0154 protein
B9N48_RS09390	COG0785	Cytochrome C biogenesis protein
B9N48_RS09395	COG2201	protein-glutamate methylesterase activity
B9N48_RS09400	COG4846	Membrane protein involved in cytochrome C biogenesis
B9N48_RS09410	COG0071	Belongs to the small heat shock protein (HSP20) family
B9N48_RS09425	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B9N48_RS09430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9N48_RS09450	COG0824	Thioesterase
B9N48_RS09460	COG4841	protein insertion into membrane
B9N48_RS09465	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B9N48_RS09470	COG1832	CoA-binding protein
B9N48_RS09475	COG0187	DNA topoisomerase II activity
B9N48_RS09480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B9N48_RS09490	COG1115	amino acid carrier protein
B9N48_RS09495	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B9N48_RS09505	COG5520	Belongs to the glycosyl hydrolase 30 family
B9N48_RS09510	COG3507	Belongs to the glycosyl hydrolase 43 family
B9N48_RS09515	COG2246	polysaccharide biosynthetic process
B9N48_RS09520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B9N48_RS09525	COG0586	Pfam SNARE associated Golgi protein
B9N48_RS09530	COG2404	hydrolase activity, acting on ester bonds
B9N48_RS09535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B9N48_RS09540	COG1024	Enoyl-CoA hydratase
B9N48_RS09545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B9N48_RS09550	COG0511	ligase activity, forming carbon-carbon bonds
B9N48_RS09555	COG0439	Biotin carboxylase
B9N48_RS09560	COG0318	PFAM AMP-dependent synthetase and ligase
B9N48_RS09565	COG1960	acyl-CoA dehydrogenase activity
B9N48_RS09575	COG1649	PFAM Uncharacterised BCR, COG1649
B9N48_RS09585	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B9N48_RS09585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9N48_RS09590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9N48_RS09595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9N48_RS09600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9N48_RS09605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9N48_RS09610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9N48_RS09615	COG2027	D-alanyl-D-alanine carboxypeptidase
B9N48_RS09620	COG2017	converts alpha-aldose to the beta-anomer
B9N48_RS09625	COG0534	Mate efflux family protein
B9N48_RS09640	COG0582	viral genome integration into host DNA
B9N48_RS09645	COG0166	Belongs to the GPI family
B9N48_RS09650	COG0405	Gamma-glutamyltransferase
B9N48_RS09660	COG0604	alcohol dehydrogenase
B9N48_RS09665	COG0493	'glutamate synthase
B9N48_RS09670	COG0070	glutamate synthase
B9N48_RS09670	COG0069	glutamate synthase activity
B9N48_RS09670	COG0067	glutamate synthase
B9N48_RS09675	COG0583	DNA-binding transcription factor activity
B9N48_RS09680	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B9N48_RS09685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B9N48_RS09695	COG0300	oxidoreductase activity
B9N48_RS09700	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
B9N48_RS09710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9N48_RS09715	COG2814	Major facilitator Superfamily
B9N48_RS09720	COG1070	Carbohydrate kinase
B9N48_RS09725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B9N48_RS09730	COG0243	molybdopterin cofactor binding
B9N48_RS09755	COG0840	transmembrane signaling receptor activity
B9N48_RS09755	COG5278	phosphoserine phosphatase activity
B9N48_RS09760	COG2368	4-hydroxyphenylacetate
B9N48_RS09765	COG4305	rare lipoprotein A
B9N48_RS09775	COG3866	Pectate lyase
B9N48_RS09780	COG2135	peptidase activity
B9N48_RS09790	COG2140	Oxalate decarboxylase
B9N48_RS09810	COG2720	vancomycin resistance protein
B9N48_RS09825	COG3739	integral membrane protein
B9N48_RS09830	COG0583	DNA-binding transcription factor activity
B9N48_RS09835	COG0697	spore germination
B9N48_RS09845	COG0693	protein deglycase activity
B9N48_RS09850	COG2367	Beta-lactamase
B9N48_RS09870	COG0726	polysaccharide deacetylase
B9N48_RS09880	COG2314	TM2 domain
B9N48_RS09885	COG1396	sequence-specific DNA binding
B9N48_RS09900	COG2135	peptidase activity
B9N48_RS09910	COG0457	Tetratricopeptide repeat
B9N48_RS09930	COG5444	nuclease activity
B9N48_RS09935	COG4282	regulation of fungal-type cell wall biogenesis
B9N48_RS09940	COG1231	oxidoreductase activity
B9N48_RS09945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9N48_RS09950	COG0662	Cupin 2, conserved barrel domain protein
B9N48_RS09950	COG2207	Transcriptional regulator
B9N48_RS09955	COG0456	acetyltransferase
B9N48_RS09960	COG1309	transcriptional regulator
B9N48_RS09965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9N48_RS09970	COG3708	Transcriptional regulator
B9N48_RS09975	COG2378	regulation of single-species biofilm formation
B9N48_RS09985	COG0640	Transcriptional regulator
B9N48_RS09990	COG0741	lytic transglycosylase activity
B9N48_RS09995	COG2322	membrane
B9N48_RS10010	COG1619	proteins homologs of microcin C7 resistance protein MccF
B9N48_RS10015	COG3239	Fatty acid desaturase
B9N48_RS10020	COG4585	Histidine kinase
B9N48_RS10025	COG2197	response regulator
B9N48_RS10030	COG1388	LysM domain
B9N48_RS10030	COG3584	3D domain protein
B9N48_RS10035	COG0514	ATP-dependent DNA helicase (RecQ)
B9N48_RS10050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B9N48_RS10055	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B9N48_RS10070	COG0071	Belongs to the small heat shock protein (HSP20) family
B9N48_RS10095	COG1012	belongs to the aldehyde dehydrogenase family
B9N48_RS10100	COG1657	PFAM Prenyltransferase squalene oxidase
B9N48_RS10105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B9N48_RS10110	COG0733	neurotransmitter:sodium symporter activity
B9N48_RS10115	COG0385	Bile acid
B9N48_RS10120	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9N48_RS10125	COG0567	Dehydrogenase, E1 component
B9N48_RS10130	COG4548	von Willebrand factor, type A
B9N48_RS10135	COG0714	Associated with various cellular activities
B9N48_RS10140	COG2032	superoxide dismutase activity
B9N48_RS10145	COG0791	NLP P60 protein
B9N48_RS10145	COG1388	LysM domain
B9N48_RS10150	COG1819	glycosyl
B9N48_RS10155	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B9N48_RS10160	COG0534	Mate efflux family protein
B9N48_RS10165	COG1366	Belongs to the anti-sigma-factor antagonist family
B9N48_RS10170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B9N48_RS10175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B9N48_RS10185	COG2962	Rard protein
B9N48_RS10200	COG2610	gluconate transmembrane transporter activity
B9N48_RS10205	COG1942	4-Oxalocrotonate Tautomerase
B9N48_RS10210	COG1733	regulation of RNA biosynthetic process
B9N48_RS10215	COG0778	Nitroreductase
B9N48_RS10220	COG0400	carboxylic ester hydrolase activity
B9N48_RS10225	COG0346	lactoylglutathione lyase activity
B9N48_RS10240	COG0793	Belongs to the peptidase S41A family
B9N48_RS10240	COG3409	Peptidoglycan-binding domain 1 protein
B9N48_RS10245	COG2226	methyltransferase
B9N48_RS10255	COG1876	peptidase activity
B9N48_RS10260	COG0813	purine-nucleoside phosphorylase activity
B9N48_RS10275	COG0671	phosphoesterase, PA-phosphatase related
B9N48_RS10300	COG4479	Belongs to the UPF0346 family
B9N48_RS10310	COG1509	lysine 2,3-aminomutase activity
B9N48_RS10315	COG0456	acetyltransferase
B9N48_RS10320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9N48_RS10325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B9N48_RS10330	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B9N48_RS10335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B9N48_RS10345	COG0456	acetyltransferase
B9N48_RS10350	COG0463	Glycosyl transferase, family 2
B9N48_RS10365	COG4641	Protein conserved in bacteria
B9N48_RS10370	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
B9N48_RS10375	COG1086	Polysaccharide biosynthesis protein
B9N48_RS10395	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B9N48_RS10420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9N48_RS10425	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9N48_RS10435	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9N48_RS10445	COG1372	Participates in initiation and elongation during chromosome replication
B9N48_RS10445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9N48_RS10450	COG1780	Probably involved in ribonucleotide reductase function
B9N48_RS10485	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B9N48_RS10510	COG3420	alginic acid biosynthetic process
B9N48_RS10510	COG5434	Belongs to the glycosyl hydrolase 28 family
B9N48_RS10515	COG4195	phage-related replication protein
B9N48_RS10525	COG2135	peptidase activity
B9N48_RS10550	COG4474	Belongs to the UPF0398 family
B9N48_RS10605	COG0776	regulation of translation
B9N48_RS10630	COG4373	Mu-like prophage FluMu protein gp28
B9N48_RS10725	COG0582	viral genome integration into host DNA
B9N48_RS10750	COG1196	nuclear chromosome segregation
B9N48_RS10750	COG0741	lytic transglycosylase activity
B9N48_RS10750	COG0739	heme binding
B9N48_RS10755	COG2433	Pfam Transposase IS66
B9N48_RS10765	COG5632	N-Acetylmuramoyl-L-alanine amidase
B9N48_RS10770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B9N48_RS10780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9N48_RS10800	COG4282	regulation of fungal-type cell wall biogenesis
B9N48_RS10805	COG1525	nuclease
B9N48_RS10815	COG2746	aminoglycoside 3-N-acetyltransferase activity
B9N48_RS10825	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B9N48_RS10830	COG1086	Polysaccharide biosynthesis protein
B9N48_RS10835	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B9N48_RS10840	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B9N48_RS10845	COG1846	Transcriptional regulator
B9N48_RS10850	COG0534	Mate efflux family protein
B9N48_RS10860	COG4698	Protein conserved in bacteria
B9N48_RS10865	COG2755	lipolytic protein G-D-S-L family
B9N48_RS10870	COG1999	signal sequence binding
B9N48_RS10880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B9N48_RS10885	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B9N48_RS10890	COG1272	protein, Hemolysin III
B9N48_RS10895	COG0204	Acyl-transferase
B9N48_RS10900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B9N48_RS10905	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B9N48_RS10910	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B9N48_RS10920	COG2136	Putative SAM-dependent methyltransferase
B9N48_RS10920	COG2521	methyltransferase
B9N48_RS10930	COG0129	dihydroxy-acid dehydratase activity
B9N48_RS10935	COG1413	lyase activity
B9N48_RS10940	COG1418	mRNA catabolic process
B9N48_RS10945	COG0386	Belongs to the glutathione peroxidase family
B9N48_RS10950	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B9N48_RS10955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B9N48_RS10960	COG1278	Cold shock
B9N48_RS10980	COG0328	RNA-DNA hybrid ribonuclease activity
B9N48_RS10985	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B9N48_RS10990	COG0328	RNA-DNA hybrid ribonuclease activity
B9N48_RS11000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B9N48_RS11015	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B9N48_RS11020	COG1755	Isoprenylcysteine carboxyl methyltransferase
B9N48_RS11025	COG3424	synthase
B9N48_RS11030	COG2233	PERMEase
B9N48_RS11035	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B9N48_RS11040	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B9N48_RS11050	COG0800	Aldolase
B9N48_RS11055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9N48_RS11060	COG1609	Transcriptional regulator
B9N48_RS11065	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
B9N48_RS11070	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS11075	COG1199	ATP-dependent helicase activity
B9N48_RS11090	COG0116	Belongs to the methyltransferase superfamily
B9N48_RS11105	COG4474	Belongs to the UPF0398 family
B9N48_RS11115	COG3359	exonuclease
B9N48_RS11120	COG1205	dead DEAH box helicase
B9N48_RS11120	COG1111	helicase
B9N48_RS11125	COG2190	(PTS) system
B9N48_RS11130	COG0071	Belongs to the small heat shock protein (HSP20) family
B9N48_RS11165	COG3331	DNA recombination
B9N48_RS11180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B9N48_RS11185	COG3935	DnaD domain protein
B9N48_RS11190	COG0017	Asparaginyl-tRNA synthetase
B9N48_RS11195	COG0436	Aminotransferase
B9N48_RS11200	COG5353	protein conserved in bacteria
B9N48_RS11210	COG1199	ATP-dependent helicase activity
B9N48_RS11210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B9N48_RS11215	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B9N48_RS11220	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B9N48_RS11225	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B9N48_RS11230	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
B9N48_RS11230	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
B9N48_RS11235	COG0617	tRNA 3'-terminal CCA addition
B9N48_RS11240	COG0438	transferase activity, transferring glycosyl groups
B9N48_RS11245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B9N48_RS11250	COG1803	Methylglyoxal synthase
B9N48_RS11255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B9N48_RS11260	COG1694	Mazg nucleotide pyrophosphohydrolase
B9N48_RS11265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B9N48_RS11275	COG4347	Protein of unknown function (DUF1405)
B9N48_RS11280	COG2010	Cytochrome c
B9N48_RS11280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B9N48_RS11285	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B9N48_RS11290	COG0723	plastoquinol--plastocyanin reductase activity
B9N48_RS11300	COG5582	Belongs to the UPF0302 family
B9N48_RS11305	COG0457	Tetratricopeptide repeat
B9N48_RS11310	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B9N48_RS11315	COG0287	Prephenate dehydrogenase
B9N48_RS11320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B9N48_RS11325	COG0159	tryptophan synthase activity
B9N48_RS11330	COG0133	tryptophan synthase activity
B9N48_RS11335	COG0135	phosphoribosylanthranilate isomerase activity
B9N48_RS11345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B9N48_RS11350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B9N48_RS11355	COG4401	Chorismate mutase type I
B9N48_RS11360	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B9N48_RS11365	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B9N48_RS11370	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B9N48_RS11375	COG0105	UTP biosynthetic process
B9N48_RS11380	COG0142	geranyltranstransferase activity
B9N48_RS11385	COG2226	methyltransferase
B9N48_RS11390	COG0142	geranyltranstransferase activity
B9N48_RS11400	COG0302	gtp cyclohydrolase
B9N48_RS11405	COG0776	regulation of translation
B9N48_RS11410	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B9N48_RS11425	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B9N48_RS11430	COG1160	GTP binding
B9N48_RS11455	COG1304	FMN binding
B9N48_RS11460	COG0539	negative regulation of cytoplasmic translation
B9N48_RS11465	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B9N48_RS11475	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B9N48_RS11480	COG2959	enzyme of heme biosynthesis
B9N48_RS11485	COG3409	Peptidoglycan-binding domain 1 protein
B9N48_RS11485	COG3773	Cell wall hydrolase
B9N48_RS11490	COG2339	peptidase activity
B9N48_RS11495	COG0492	ferredoxin-NADP+ reductase activity
B9N48_RS11500	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B9N48_RS11505	COG4862	establishment of competence for transformation
B9N48_RS11510	COG1408	metallophosphoesterase
B9N48_RS11520	COG1388	LysM domain
B9N48_RS11525	COG1266	CAAX protease self-immunity
B9N48_RS11530	COG0514	ATP-dependent DNA helicase (RecQ)
B9N48_RS11535	COG4955	Helix-turn-helix domain
B9N48_RS11540	COG1141	Ferredoxin
B9N48_RS11545	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B9N48_RS11550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B9N48_RS11555	COG0710	3-dehydroquinate dehydratase activity
B9N48_RS11565	COG1595	DNA-templated transcription, initiation
B9N48_RS11570	COG5002	protein histidine kinase activity
B9N48_RS11575	COG0745	RESPONSE REGULATOR receiver
B9N48_RS11580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B9N48_RS11585	COG1333	cytochrome c biogenesis protein
B9N48_RS11590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9N48_RS11595	COG1187	pseudouridine synthase activity
B9N48_RS11600	COG0700	Nucleoside recognition
B9N48_RS11605	COG2715	membrane protein required for spore maturation
B9N48_RS11610	COG1686	Belongs to the peptidase S11 family
B9N48_RS11620	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B9N48_RS11625	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B9N48_RS11630	COG1547	Domain of unknown function (DUF309)
B9N48_RS11635	COG0456	acetyltransferase
B9N48_RS11640	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B9N48_RS11645	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B9N48_RS11645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B9N48_RS11650	COG0307	riboflavin synthase, alpha
B9N48_RS11655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B9N48_RS11655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B9N48_RS11665	COG0681	Belongs to the peptidase S26 family
B9N48_RS11675	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
B9N48_RS11705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B9N48_RS11715	COG4086	secreted protein
B9N48_RS11720	COG0019	diaminopimelate decarboxylase activity
B9N48_RS11725	COG0697	spore germination
B9N48_RS11740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B9N48_RS11760	COG1191	sigma factor activity
B9N48_RS11765	COG2172	sigma factor antagonist activity
B9N48_RS11770	COG1366	Belongs to the anti-sigma-factor antagonist family
B9N48_RS11775	COG1686	Belongs to the peptidase S11 family
B9N48_RS11780	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B9N48_RS11785	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B9N48_RS11790	COG4974	Belongs to the 'phage' integrase family
B9N48_RS11800	COG0735	belongs to the Fur family
B9N48_RS11805	COG1300	Membrane
B9N48_RS11815	COG0281	malic enzyme
B9N48_RS11820	COG1757	Na H antiporter
B9N48_RS11825	COG1027	Aspartate ammonia-lyase
B9N48_RS11830	COG0252	asparaginase activity
B9N48_RS11835	COG1396	sequence-specific DNA binding
B9N48_RS11840	COG1379	DNA repair
B9N48_RS11845	COG0494	nUDIX hydrolase
B9N48_RS11855	COG0667	Aldo Keto reductase
B9N48_RS11865	COG1073	alpha beta
B9N48_RS11875	COG4918	Iron-sulphur cluster biosynthesis
B9N48_RS11880	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B9N48_RS11880	COG0456	acetyltransferase
B9N48_RS11885	COG2329	Antibiotic biosynthesis monooxygenase
B9N48_RS11890	COG0456	acetyltransferase
B9N48_RS11900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B9N48_RS11910	COG2211	Major facilitator Superfamily
B9N48_RS11920	COG0346	lactoylglutathione lyase activity
B9N48_RS11925	COG1072	(Pantothenic acid kinase))
B9N48_RS11930	COG3048	D-serine ammonia-lyase activity
B9N48_RS11935	COG0300	oxidoreductase activity
B9N48_RS11940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9N48_RS11945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B9N48_RS11950	COG4187	Peptidase family M20/M25/M40
B9N48_RS11955	COG1902	pentaerythritol trinitrate reductase activity
B9N48_RS11960	COG0596	Alpha beta hydrolase
B9N48_RS11970	COG1234	tRNA 3'-trailer cleavage
B9N48_RS11975	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B9N48_RS11980	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B9N48_RS11985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B9N48_RS11995	COG0706	membrane insertase activity
B9N48_RS12000	COG3361	conserved protein (COG2071)
B9N48_RS12005	COG2195	Cleaves the N-terminal amino acid of tripeptides
B9N48_RS12010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B9N48_RS12015	COG0346	lactoylglutathione lyase activity
B9N48_RS12020	COG1376	ErfK ybiS ycfS ynhG family protein
B9N48_RS12025	COG4129	membrane
B9N48_RS12030	COG1126	abc transporter atp-binding protein
B9N48_RS12035	COG0765	amino acid transport
B9N48_RS12040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9N48_RS12050	COG1597	lipid kinase activity
B9N48_RS12055	COG2814	Major facilitator Superfamily
B9N48_RS12060	COG0789	Transcriptional regulator
B9N48_RS12060	COG4978	Transcriptional regulator
B9N48_RS12065	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9N48_RS12070	COG0022	dehydrogenase e1 component
B9N48_RS12075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B9N48_RS12080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B9N48_RS12085	COG3426	butyrate kinase activity
B9N48_RS12090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B9N48_RS12095	COG0280	phosphate acetyltransferase
B9N48_RS12100	COG3290	protein histidine kinase activity
B9N48_RS12100	COG3829	transcription factor binding
B9N48_RS12110	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B9N48_RS12115	COG2079	MmgE PrpD family protein
B9N48_RS12120	COG0372	Belongs to the citrate synthase family
B9N48_RS12125	COG1960	acyl-CoA dehydrogenase activity
B9N48_RS12130	COG1250	3-hydroxyacyl-CoA dehydrogenase
B9N48_RS12135	COG0183	Belongs to the thiolase family
B9N48_RS12140	COG0584	glycerophosphoryl diester phosphodiesterase
B9N48_RS12145	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9N48_RS12155	COG1902	pentaerythritol trinitrate reductase activity
B9N48_RS12160	COG0745	RESPONSE REGULATOR receiver
B9N48_RS12170	COG0750	zinc metalloprotease
B9N48_RS12175	COG0497	DNA recombination
B9N48_RS12180	COG1438	arginine binding
B9N48_RS12185	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B9N48_RS12190	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B9N48_RS12195	COG0142	geranyltranstransferase activity
B9N48_RS12200	COG1722	exodeoxyribonuclease VII activity
B9N48_RS12205	COG1570	exodeoxyribonuclease VII activity
B9N48_RS12210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B9N48_RS12215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B9N48_RS12220	COG1302	Protein conserved in bacteria
B9N48_RS12225	COG0439	Biotin carboxylase
B9N48_RS12230	COG0511	ligase activity, forming carbon-carbon bonds
B9N48_RS12270	COG3854	ATPases associated with a variety of cellular activities
B9N48_RS12280	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B9N48_RS12285	COG0006	proline dipeptidase activity
B9N48_RS12290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B9N48_RS12300	COG3872	metal-dependent enzyme
B9N48_RS12310	COG1752	Esterase of the alpha-beta hydrolase superfamily
B9N48_RS12315	COG1321	iron dependent repressor
B9N48_RS12320	COG0095	Lipoate-protein ligase
B9N48_RS12325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B9N48_RS12330	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B9N48_RS12335	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B9N48_RS12340	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B9N48_RS12345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B9N48_RS12360	COG1396	sequence-specific DNA binding
B9N48_RS12370	COG0681	Belongs to the peptidase S26 family
B9N48_RS12395	COG4940	Competence protein ComGF
B9N48_RS12405	COG4970	Tfp pilus assembly protein FimT
B9N48_RS12410	COG4537	Required for transformation and DNA binding
B9N48_RS12415	COG1459	type II secretion system
B9N48_RS12420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B9N48_RS12425	COG0517	IMP dehydrogenase activity
B9N48_RS12430	COG0598	Magnesium transport protein CorA
B9N48_RS12435	COG1253	flavin adenine dinucleotide binding
B9N48_RS12440	COG1366	Belongs to the anti-sigma-factor antagonist family
B9N48_RS12450	COG1393	Belongs to the ArsC family
B9N48_RS12460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9N48_RS12470	COG0011	TIGRFAM Protein of
B9N48_RS12480	COG2866	Carboxypeptidase
B9N48_RS12485	COG1368	sulfuric ester hydrolase activity
B9N48_RS12490	COG1940	carbohydrate kinase activity
B9N48_RS12495	COG4483	Protein conserved in bacteria
B9N48_RS12500	COG0705	Rhomboid family
B9N48_RS12500	COG0457	Tetratricopeptide repeat
B9N48_RS12510	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B9N48_RS12520	COG0438	transferase activity, transferring glycosyl groups
B9N48_RS12535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B9N48_RS12540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B9N48_RS12545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B9N48_RS12550	COG0581	inorganic phosphate transmembrane transporter activity
B9N48_RS12555	COG0573	inorganic phosphate transmembrane transporter activity
B9N48_RS12560	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B9N48_RS12565	COG0768	penicillin binding
B9N48_RS12570	COG0477	Major facilitator Superfamily
B9N48_RS12575	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B9N48_RS12580	COG2839	Protein conserved in bacteria
B9N48_RS12585	COG5521	maltodextrose utilization protein MalA
B9N48_RS12590	COG1388	LysM domain
B9N48_RS12595	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B9N48_RS12600	COG4709	membrane
B9N48_RS12605	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
B9N48_RS12610	COG0735	belongs to the Fur family
B9N48_RS12615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B9N48_RS12625	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B9N48_RS12630	COG0513	Belongs to the DEAD box helicase family
B9N48_RS12640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B9N48_RS12645	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B9N48_RS12650	COG2384	SAM-dependent methyltransferase
B9N48_RS12655	COG2010	Cytochrome c
B9N48_RS12660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B9N48_RS12665	COG0358	DNA primase activity
B9N48_RS12670	COG1671	Belongs to the UPF0178 family
B9N48_RS12675	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B9N48_RS12680	COG0517	IMP dehydrogenase activity
B9N48_RS12685	COG0751	glycine-tRNA ligase activity
B9N48_RS12690	COG0752	glycyl-tRNA synthetase alpha subunit
B9N48_RS12695	COG1381	Involved in DNA repair and RecF pathway recombination
B9N48_RS12705	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B9N48_RS12710	COG0295	cytidine deaminase activity
B9N48_RS12715	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B9N48_RS12720	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B9N48_RS12725	COG1480	7TM receptor with intracellular HD hydrolase
B9N48_RS12730	COG1702	phosphate starvation-inducible protein PhoH
B9N48_RS12735	COG0561	phosphatase activity
B9N48_RS12750	COG4864	UPF0365 protein
B9N48_RS12755	COG1030	water channel activity
B9N48_RS12760	COG1610	YqeY-like protein
B9N48_RS12770	COG1283	sodium-dependent phosphate transmembrane transporter activity
B9N48_RS12775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B9N48_RS12780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B9N48_RS12785	COG2264	protein methyltransferase activity
B9N48_RS12790	COG0484	heat shock protein binding
B9N48_RS12795	COG0443	Heat shock 70 kDa protein
B9N48_RS12800	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B9N48_RS12805	COG1420	regulation of RNA biosynthetic process
B9N48_RS12810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B9N48_RS12815	COG0481	GTPase activity
B9N48_RS12825	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9N48_RS12830	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B9N48_RS12835	COG0268	Binds directly to 16S ribosomal RNA
B9N48_RS12840	COG1466	dna polymerase III delta subunit
B9N48_RS12850	COG2333	competence protein COMEC
B9N48_RS12850	COG0658	competence protein
B9N48_RS12855	COG2131	deaminase
B9N48_RS12860	COG1596	polysaccharide export
B9N48_RS12860	COG1555	photosystem II stabilization
B9N48_RS12865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B9N48_RS12870	COG2226	methyltransferase
B9N48_RS12875	COG0799	negative regulation of ribosome biogenesis
B9N48_RS12880	COG1713	HD superfamily hydrolase involved in NAD metabolism
B9N48_RS12885	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B9N48_RS12890	COG1534	Rna-binding protein
B9N48_RS12895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B9N48_RS12900	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B9N48_RS12905	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
B9N48_RS12915	COG2755	lipolytic protein G-D-S-L family
B9N48_RS12920	COG3409	Peptidoglycan-binding domain 1 protein
B9N48_RS12920	COG5632	N-Acetylmuramoyl-L-alanine amidase
B9N48_RS12925	COG0398	Pfam SNARE associated Golgi protein
B9N48_RS12930	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B9N48_RS12940	COG3209	COG3209 Rhs family protein
B9N48_RS12950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B9N48_RS12970	COG1783	phage Terminase large subunit
B9N48_RS12975	COG5484	DNA packaging
B9N48_RS12980	COG3677	Transposase
B9N48_RS12990	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B9N48_RS13000	COG1484	DNA-dependent DNA replication
B9N48_RS13010	COG0730	response to heat
B9N48_RS13015	COG0425	Belongs to the sulfur carrier protein TusA family
B9N48_RS13030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B9N48_RS13030	COG0425	Belongs to the sulfur carrier protein TusA family
B9N48_RS13040	COG2210	Belongs to the sulfur carrier protein TusA family
B9N48_RS13045	COG1937	Protein conserved in bacteria
B9N48_RS13060	COG0662	Cupin 2, conserved barrel domain protein
B9N48_RS13075	COG0789	Transcriptional regulator
B9N48_RS13075	COG4978	Transcriptional regulator
B9N48_RS13080	COG2814	Major facilitator Superfamily
B9N48_RS13085	COG0456	acetyltransferase
B9N48_RS13090	COG1253	flavin adenine dinucleotide binding
B9N48_RS13100	COG0697	spore germination
B9N48_RS13105	COG0583	DNA-binding transcription factor activity
B9N48_RS13110	COG2072	flavoprotein involved in K transport
B9N48_RS13115	COG1230	cation diffusion facilitator family transporter
B9N48_RS13120	COG1942	4-Oxalocrotonate Tautomerase
B9N48_RS13125	COG1114	Component of the transport system for branched-chain amino acids
B9N48_RS13130	COG1687	branched-chain amino acid
B9N48_RS13135	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B9N48_RS13140	COG1522	sequence-specific DNA binding
B9N48_RS13145	COG2732	(Barnase) inhibitor
B9N48_RS13150	COG2124	cytochrome p450
B9N48_RS13160	COG1335	isochorismatase
B9N48_RS13175	COG2318	DinB family
B9N48_RS13185	COG2070	2-Nitropropane dioxygenase
B9N48_RS13200	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B9N48_RS13215	COG3443	Belongs to the bacterial solute-binding protein 9 family
B9N48_RS13220	COG1595	DNA-templated transcription, initiation
B9N48_RS13225	COG0667	Aldo Keto reductase
B9N48_RS13230	COG2851	Citrate transporter
B9N48_RS13235	COG3409	Peptidoglycan-binding domain 1 protein
B9N48_RS13240	COG5566	PFAM Mor transcription activator
B9N48_RS13245	COG0596	Alpha beta hydrolase
B9N48_RS13250	COG4991	sh3 domain protein
B9N48_RS13255	COG4991	sh3 domain protein
B9N48_RS13260	COG0346	lactoylglutathione lyase activity
B9N48_RS13270	COG5577	PFAM Coat F domain
B9N48_RS13275	COG1063	alcohol dehydrogenase
B9N48_RS13285	COG5577	PFAM Coat F domain
B9N48_RS13290	COG0789	Transcriptional regulator
B9N48_RS13300	COG1064	alcohol dehydrogenase
B9N48_RS13305	COG0693	protein deglycase activity
B9N48_RS13310	COG1621	beta-fructofuranosidase activity
B9N48_RS13315	COG3716	PTS system mannose fructose sorbose family IID component
B9N48_RS13320	COG3715	PTS system
B9N48_RS13325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9N48_RS13330	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9N48_RS13335	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B9N48_RS13335	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B9N48_RS13340	COG1113	amino acid transport
B9N48_RS13345	COG1280	lysine exporter protein (LysE YggA)
B9N48_RS13350	COG1378	Sugar-specific transcriptional regulator TrmB
B9N48_RS13355	COG1595	DNA-templated transcription, initiation
B9N48_RS13365	COG2755	lipolytic protein G-D-S-L family
B9N48_RS13365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B9N48_RS13375	COG2124	cytochrome p450
B9N48_RS13375	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B9N48_RS13380	COG1309	transcriptional regulator
B9N48_RS13385	COG2226	methyltransferase
B9N48_RS13395	COG2116	formate transmembrane transporter activity
B9N48_RS13400	COG5609	conserved protein (DUF2294)
B9N48_RS13405	COG3383	formate dehydrogenase (NAD+) activity
B9N48_RS13410	COG2427	Protein of unknown function (DUF1641)
B9N48_RS13420	COG0626	cystathionine gamma-synthase activity
B9N48_RS13425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B9N48_RS13430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B9N48_RS13435	COG2226	methyltransferase
B9N48_RS13450	COG0768	penicillin binding
B9N48_RS13455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B9N48_RS13460	COG0572	uridine kinase
B9N48_RS13465	COG0826	peptidase U32
B9N48_RS13470	COG0826	peptidase U32
B9N48_RS13475	COG4122	O-methyltransferase activity
B9N48_RS13480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B9N48_RS13485	COG3906	Belongs to the UPF0473 family
B9N48_RS13490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B9N48_RS13495	COG4472	Bacterial protein of unknown function (DUF965)
B9N48_RS13500	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B9N48_RS13505	COG0628	permease
B9N48_RS13510	COG1126	abc transporter atp-binding protein
B9N48_RS13515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9N48_RS13520	COG0765	amino acid transport
B9N48_RS13525	COG0765	amino acid transport
B9N48_RS13540	COG3881	PFAM PRC-barrel domain
B9N48_RS13545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B9N48_RS13550	COG0457	Tetratricopeptide repeat
B9N48_RS13555	COG0482	sulfurtransferase activity
B9N48_RS13560	COG1104	cysteine desulfurase activity
B9N48_RS13565	COG1959	2 iron, 2 sulfur cluster binding
B9N48_RS13570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B9N48_RS13575	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B9N48_RS13585	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B9N48_RS13590	COG0124	histidyl-tRNA synthetase
B9N48_RS13600	COG3103	Sh3 type 3 domain protein
B9N48_RS13600	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9N48_RS13600	COG4991	sh3 domain protein
B9N48_RS13605	COG1490	D-aminoacyl-tRNA deacylase activity
B9N48_RS13610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B9N48_RS13615	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B9N48_RS13620	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B9N48_RS13620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B9N48_RS13625	COG5416	Lipopolysaccharide assembly protein A domain
B9N48_RS13630	COG0490	domain, Protein
B9N48_RS13635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B9N48_RS13635	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B9N48_RS13645	COG2244	polysaccharide biosynthetic process
B9N48_RS13650	COG2323	membrane
B9N48_RS13660	COG1862	Preprotein translocase
B9N48_RS13665	COG0343	queuine tRNA-ribosyltransferase activity
B9N48_RS13670	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B9N48_RS13680	COG2255	four-way junction helicase activity
B9N48_RS13685	COG0632	four-way junction helicase activity
B9N48_RS13695	COG2814	Major facilitator Superfamily
B9N48_RS13700	COG0673	inositol 2-dehydrogenase activity
B9N48_RS13705	COG2112	serine threonine protein kinase
B9N48_RS13720	COG1115	amino acid carrier protein
B9N48_RS13725	COG0217	transcriptional regulatory protein
B9N48_RS13735	COG1388	LysM domain
B9N48_RS13740	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B9N48_RS13745	COG0157	Belongs to the NadC ModD family
B9N48_RS13750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B9N48_RS13755	COG1104	cysteine desulfurase activity
B9N48_RS13760	COG1827	regulation of RNA biosynthetic process
B9N48_RS13765	COG0077	Prephenate dehydratase
B9N48_RS13770	COG4492	Belongs to the UPF0735 family
B9N48_RS13775	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B9N48_RS13780	COG3290	protein histidine kinase activity
B9N48_RS13785	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B9N48_RS13790	COG2868	ribosomal protein
B9N48_RS13795	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B9N48_RS13800	COG1994	Peptidase M50
B9N48_RS13805	COG0739	heme binding
B9N48_RS13810	COG2894	cell division
B9N48_RS13815	COG0850	regulation of cytokinetic process
B9N48_RS13820	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B9N48_RS13830	COG1077	Cell shape determining protein MreB Mrl
B9N48_RS13835	COG2003	Belongs to the UPF0758 family
B9N48_RS13840	COG0424	maF-like protein
B9N48_RS13850	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B9N48_RS13855	COG0285	dihydrofolate synthase activity
B9N48_RS13860	COG0525	valine-tRNA ligase activity
B9N48_RS13870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B9N48_RS13875	COG1388	LysM domain
B9N48_RS13880	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B9N48_RS13885	COG0113	porphobilinogen synthase activity
B9N48_RS13890	COG1587	Uroporphyrinogen-III synthase
B9N48_RS13895	COG0181	hydroxymethylbilane synthase activity
B9N48_RS13900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B9N48_RS13905	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B9N48_RS13915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B9N48_RS13920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B9N48_RS13925	COG1067	ATP-dependent peptidase activity
B9N48_RS13925	COG0470	DNA polymerase III
B9N48_RS13930	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B9N48_RS13935	COG0544	peptidyl-prolyl cis-trans isomerase activity
B9N48_RS13940	COG0457	Tetratricopeptide repeat
B9N48_RS13940	COG1477	protein flavinylation
B9N48_RS13945	COG0066	3-isopropylmalate dehydratase activity
B9N48_RS13950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B9N48_RS13955	COG0473	3-isopropylmalate dehydrogenase activity
B9N48_RS13960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B9N48_RS13965	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B9N48_RS13970	COG0440	acetolactate synthase activity
B9N48_RS13975	COG0028	Belongs to the TPP enzyme family
B9N48_RS13990	COG0454	-acetyltransferase
B9N48_RS13995	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
B9N48_RS14005	COG0622	Phosphoesterase
B9N48_RS14010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B9N48_RS14015	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B9N48_RS14020	COG5401	PFAM Sporulation and spore germination
B9N48_RS14025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B9N48_RS14030	COG1846	Transcriptional regulator
B9N48_RS14035	COG2197	response regulator
B9N48_RS14040	COG0824	Thioesterase
B9N48_RS14045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B9N48_RS14050	COG1053	succinate dehydrogenase
B9N48_RS14055	COG2009	succinate dehydrogenase
B9N48_RS14060	COG1719	4-vinyl reductase, 4VR
B9N48_RS14065	COG0527	aspartate kinase activity
B9N48_RS14075	COG0322	excinuclease ABC activity
B9N48_RS14080	COG3118	belongs to the thioredoxin family
B9N48_RS14090	COG3534	alpha-L-arabinofuranosidase
B9N48_RS14095	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B9N48_RS14100	COG2086	electron transfer activity
B9N48_RS14105	COG1024	Enoyl-CoA hydratase
B9N48_RS14110	COG1309	transcriptional regulator
B9N48_RS14115	COG0318	PFAM AMP-dependent synthetase and ligase
B9N48_RS14125	COG3766	membrane
B9N48_RS14130	COG1193	negative regulation of DNA recombination
B9N48_RS14135	COG1796	DNA polymerase
B9N48_RS14135	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B9N48_RS14140	COG1286	toxin biosynthetic process
B9N48_RS14145	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
B9N48_RS14150	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B9N48_RS14155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9N48_RS14155	COG0072	phenylalanine-tRNA ligase activity
B9N48_RS14160	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B9N48_RS14170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9N48_RS14180	COG3835	regulator
B9N48_RS14185	COG0277	FAD linked oxidase domain protein
B9N48_RS14190	COG0247	lactate metabolic process
B9N48_RS14195	COG0346	lactoylglutathione lyase activity
B9N48_RS14205	COG1966	Carbon starvation protein
B9N48_RS14210	COG3534	alpha-L-arabinofuranosidase
B9N48_RS14215	COG0395	ABC-type sugar transport system, permease component
B9N48_RS14220	COG1175	transmembrane transport
B9N48_RS14225	COG1653	transport
B9N48_RS14230	COG0371	Dehydrogenase
B9N48_RS14235	COG0647	UMP catabolic process
B9N48_RS14240	COG0235	Class ii aldolase
B9N48_RS14245	COG1069	ribulokinase activity
B9N48_RS14250	COG2160	L-arabinose isomerase activity
B9N48_RS14255	COG3507	Belongs to the glycosyl hydrolase 43 family
B9N48_RS14260	COG1363	Peptidase, m42
B9N48_RS14270	COG3326	Membrane
B9N48_RS14275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B9N48_RS14280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B9N48_RS14285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B9N48_RS14295	COG1346	cytolysis
B9N48_RS14300	COG1380	Effector of murein hydrolase LrgA
B9N48_RS14305	COG3279	Response regulator of the LytR AlgR family
B9N48_RS14310	COG3275	phosphorelay sensor kinase activity
B9N48_RS14315	COG1011	Hydrolase
B9N48_RS14320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B9N48_RS14330	COG0398	Pfam SNARE associated Golgi protein
B9N48_RS14335	COG1484	DNA-dependent DNA replication
B9N48_RS14340	COG3611	Membrane attachment protein
B9N48_RS14345	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B9N48_RS14350	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B9N48_RS14355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B9N48_RS14360	COG1733	regulation of RNA biosynthetic process
B9N48_RS14365	COG2814	Major facilitator Superfamily
B9N48_RS14370	COG0656	L-ascorbic acid biosynthetic process
B9N48_RS14375	COG0237	dephospho-CoA kinase activity
B9N48_RS14380	COG1971	Probably functions as a manganese efflux pump
B9N48_RS14385	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B9N48_RS14390	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B9N48_RS14390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B9N48_RS14395	COG5002	protein histidine kinase activity
B9N48_RS14400	COG0745	RESPONSE REGULATOR receiver
B9N48_RS14405	COG0039	L-malate dehydrogenase activity
B9N48_RS14410	COG0538	isocitrate dehydrogenase activity
B9N48_RS14415	COG0372	Belongs to the citrate synthase family
B9N48_RS14420	COG2707	UPF0756 membrane protein
B9N48_RS14425	COG0628	permease
B9N48_RS14430	COG3030	protein affecting phage T7 exclusion by the F plasmid
B9N48_RS14435	COG0469	pyruvate kinase activity
B9N48_RS14440	COG0205	6-phosphofructokinase activity
B9N48_RS14445	COG0825	malonyl-CoA metabolic process
B9N48_RS14450	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B9N48_RS14455	COG0281	malic enzyme
B9N48_RS14460	COG0587	DNA-directed DNA polymerase activity
B9N48_RS14480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B9N48_RS14490	COG4109	DRTGG domain
B9N48_RS14495	COG0730	response to heat
B9N48_RS14500	COG1473	amidohydrolase
B9N48_RS14505	COG0196	riboflavin kinase activity
B9N48_RS14510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9N48_RS14515	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B9N48_RS14520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9N48_RS14525	COG1126	abc transporter atp-binding protein
B9N48_RS14530	COG0765	amino acid transport
B9N48_RS14535	COG0765	amino acid transport
B9N48_RS14540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9N48_RS14545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9N48_RS14550	COG0454	-acetyltransferase
B9N48_RS14555	COG0583	DNA-binding transcription factor activity
B9N48_RS14560	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B9N48_RS14565	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS14575	COG0165	Argininosuccinate lyase
B9N48_RS14580	COG0137	argininosuccinate synthase activity
B9N48_RS14585	COG0521	Mo-molybdopterin cofactor biosynthetic process
B9N48_RS14590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B9N48_RS14600	COG0827	DNA restriction-modification system
B9N48_RS14605	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B9N48_RS14610	COG3874	Sporulation protein YtfJ
B9N48_RS14620	COG1714	RDD family
B9N48_RS14625	COG0616	signal peptide processing
B9N48_RS14630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B9N48_RS14635	COG1574	metal-dependent hydrolase with the TIM-barrel fold
B9N48_RS14640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B9N48_RS14650	COG0301	tRNA thio-modification
B9N48_RS14655	COG1104	cysteine desulfurase activity
B9N48_RS14660	COG1114	Component of the transport system for branched-chain amino acids
B9N48_RS14665	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
B9N48_RS14670	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B9N48_RS14675	COG1309	transcriptional regulator
B9N48_RS14680	COG1956	GAF domain-containing protein
B9N48_RS14685	COG2199	diguanylate cyclase activity
B9N48_RS14685	COG2203	Gaf domain
B9N48_RS14695	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B9N48_RS14700	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B9N48_RS14710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B9N48_RS14715	COG0454	-acetyltransferase
B9N48_RS14720	COG0517	IMP dehydrogenase activity
B9N48_RS14725	COG0123	including yeast histone deacetylase and acetoin utilization protein
B9N48_RS14730	COG1360	Flagellar Motor Protein
B9N48_RS14735	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B9N48_RS14740	COG1609	Transcriptional regulator
B9N48_RS14745	COG1605	Chorismate mutase
B9N48_RS14745	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B9N48_RS14750	COG3118	belongs to the thioredoxin family
B9N48_RS14755	COG4980	gas vesicle protein
B9N48_RS14760	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
B9N48_RS14765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B9N48_RS14770	COG1674	ftsk spoiiie
B9N48_RS14775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9N48_RS14780	COG4848	Belongs to the UPF0354 family
B9N48_RS14785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9N48_RS14795	COG1363	Peptidase, m42
B9N48_RS14800	COG5584	Small secreted protein
B9N48_RS14805	COG0281	malic enzyme
B9N48_RS14810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9N48_RS14815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B9N48_RS14825	COG0510	thiamine kinase activity
B9N48_RS14830	COG1523	belongs to the glycosyl hydrolase 13 family
B9N48_RS14835	COG1597	lipid kinase activity
B9N48_RS14845	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B9N48_RS14850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B9N48_RS14855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9N48_RS14860	COG2252	PERMEase
B9N48_RS14865	COG4473	ABC transporter
B9N48_RS14870	COG1131	(ABC) transporter
B9N48_RS14875	COG1349	DNA-binding transcription factor activity
B9N48_RS14880	COG1187	pseudouridine synthase activity
B9N48_RS14885	COG2244	polysaccharide biosynthetic process
B9N48_RS14890	COG2081	HI0933 family
B9N48_RS14895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B9N48_RS14905	COG5578	integral membrane protein
B9N48_RS14910	COG0673	inositol 2-dehydrogenase activity
B9N48_RS14915	COG1653	transport
B9N48_RS14920	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B9N48_RS14925	COG4209	transmembrane transport
B9N48_RS14930	COG2207	Transcriptional regulator
B9N48_RS14935	COG1653	transport
B9N48_RS14940	COG0395	ABC-type sugar transport system, permease component
B9N48_RS14945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9N48_RS14950	COG2124	cytochrome p450
B9N48_RS14955	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B9N48_RS14965	COG0156	8-amino-7-oxononanoate synthase activity
B9N48_RS14970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B9N48_RS14975	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
B9N48_RS14980	COG1073	alpha beta
B9N48_RS14985	COG1609	Transcriptional regulator
B9N48_RS14990	COG1653	transport
B9N48_RS14995	COG1175	transmembrane transport
B9N48_RS15000	COG0395	ABC-type sugar transport system, permease component
B9N48_RS15005	COG1486	melibiose metabolic process
B9N48_RS15010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B9N48_RS15015	COG0495	leucyl-tRNA aminoacylation
B9N48_RS15025	COG1366	Belongs to the anti-sigma-factor antagonist family
B9N48_RS15025	COG2202	Pas domain
B9N48_RS15030	COG2814	Major facilitator Superfamily
B9N48_RS15035	COG2433	Pfam Transposase IS66
B9N48_RS15040	COG0577	efflux transmembrane transporter activity
B9N48_RS15045	COG1136	(ABC) transporter
B9N48_RS15050	COG2205	protein histidine kinase activity
B9N48_RS15055	COG0745	RESPONSE REGULATOR receiver
B9N48_RS15060	COG0577	efflux transmembrane transporter activity
B9N48_RS15065	COG1136	(ABC) transporter
B9N48_RS15080	COG1131	(ABC) transporter
B9N48_RS15085	COG1725	Transcriptional regulator
B9N48_RS15095	COG1242	4 iron, 4 sulfur cluster binding
B9N48_RS15100	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B9N48_RS15110	COG2267	carboxylic ester hydrolase activity
B9N48_RS15115	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B9N48_RS15120	COG1113	amino acid transport
B9N48_RS15125	COG0367	asparagine synthase
B9N48_RS15130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B9N48_RS15135	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B9N48_RS15145	COG1506	peptidase
B9N48_RS15150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B9N48_RS15155	COG1116	anion transmembrane transporter activity
B9N48_RS15160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B9N48_RS15165	COG0494	nUDIX hydrolase
B9N48_RS15170	COG4824	toxin secretion phage lysis holin
B9N48_RS15175	COG0783	Belongs to the Dps family
B9N48_RS15190	COG1854	S-ribosylhomocysteine lyase activity
B9N48_RS15195	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B9N48_RS15200	COG0288	reversible hydration of carbon dioxide
B9N48_RS15205	COG0254	rRNA binding
B9N48_RS15210	COG1271	oxidase subunit
B9N48_RS15215	COG1294	oxidase, subunit
B9N48_RS15225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B9N48_RS15230	COG1321	iron dependent repressor
B9N48_RS15230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B9N48_RS15235	COG1121	(ABC) transporter
B9N48_RS15240	COG0803	Belongs to the bacterial solute-binding protein 9 family
B9N48_RS15245	COG4948	Mandelate Racemase Muconate Lactonizing
B9N48_RS15250	COG0318	PFAM AMP-dependent synthetase and ligase
B9N48_RS15255	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B9N48_RS15260	COG0596	Alpha beta hydrolase
B9N48_RS15265	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B9N48_RS15270	COG1169	isochorismate synthase
B9N48_RS15280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B9N48_RS15285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B9N48_RS15290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B9N48_RS15295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9N48_RS15300	COG0438	transferase activity, transferring glycosyl groups
B9N48_RS15310	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B9N48_RS15315	COG0438	transferase activity, transferring glycosyl groups
B9N48_RS15320	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B9N48_RS15325	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
B9N48_RS15330	COG0058	SHG alpha-glucan phosphorylase activity
B9N48_RS15335	COG0297	glycogen (starch) synthase activity
B9N48_RS15340	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B9N48_RS15345	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B9N48_RS15350	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B9N48_RS15475	COG3859	Proton-coupled thiamine transporter YuaJ
B9N48_RS15480	COG1247	-acetyltransferase
B9N48_RS15485	COG2268	Band 7 protein
B9N48_RS15490	COG1585	Membrane protein implicated in regulation of membrane protease activity
B9N48_RS15495	COG2318	DinB family
B9N48_RS15505	COG1454	alcohol dehydrogenase
B9N48_RS15510	COG1012	belongs to the aldehyde dehydrogenase family
B9N48_RS15515	COG1510	regulation of RNA biosynthetic process
B9N48_RS15525	COG0569	domain protein
B9N48_RS15530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B9N48_RS15535	COG4682	membrane
B9N48_RS15540	COG1705	Flagellar rod assembly protein muramidase FlgJ
B9N48_RS15545	COG0477	Major facilitator Superfamily
B9N48_RS15550	COG5553	Cysteine dioxygenase type I
B9N48_RS15560	COG1968	undecaprenyl-diphosphatase activity
B9N48_RS15565	COG0628	permease
B9N48_RS15570	COG0673	inositol 2-dehydrogenase activity
B9N48_RS15575	COG4806	L-rhamnose isomerase
B9N48_RS15580	COG3254	rhamnose metabolic process
B9N48_RS15585	COG1070	Carbohydrate kinase
B9N48_RS15590	COG1349	DNA-binding transcription factor activity
B9N48_RS15595	COG3347	Dehydrogenase
B9N48_RS15595	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS15605	COG0840	transmembrane signaling receptor activity
B9N48_RS15610	COG0840	transmembrane signaling receptor activity
B9N48_RS15615	COG0840	transmembrane signaling receptor activity
B9N48_RS15620	COG0840	transmembrane signaling receptor activity
B9N48_RS15635	COG0432	Pfam Uncharacterised protein family UPF0047
B9N48_RS15640	COG0366	Alpha amylase catalytic
B9N48_RS15645	COG1253	flavin adenine dinucleotide binding
B9N48_RS15650	COG2738	Putative neutral zinc metallopeptidase
B9N48_RS15665	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B9N48_RS15680	COG0166	Belongs to the GPI family
B9N48_RS15685	COG1979	alcohol dehydrogenase
B9N48_RS15690	COG1979	alcohol dehydrogenase
B9N48_RS15695	COG2155	Conserved Protein
B9N48_RS15700	COG1098	S1 RNA binding domain
B9N48_RS15705	COG0436	Aminotransferase
B9N48_RS15710	COG1522	sequence-specific DNA binding
B9N48_RS15715	COG2267	carboxylic ester hydrolase activity
B9N48_RS15725	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B9N48_RS15730	COG2205	protein histidine kinase activity
B9N48_RS15740	COG5018	Exonuclease
B9N48_RS15750	COG2814	Major facilitator Superfamily
B9N48_RS15755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B9N48_RS15760	COG3011	Protein conserved in bacteria
B9N48_RS15770	COG3290	protein histidine kinase activity
B9N48_RS15775	COG4565	transcriptional regulatory protein
B9N48_RS15780	COG1744	ABC transporter substrate-binding protein PnrA-like
B9N48_RS15785	COG3845	ABC transporter
B9N48_RS15790	COG4603	Belongs to the binding-protein-dependent transport system permease family
B9N48_RS15795	COG1079	Belongs to the binding-protein-dependent transport system permease family
B9N48_RS15800	COG3493	citrate carrier protein
B9N48_RS15810	COG2111	Na H antiporter
B9N48_RS15810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B9N48_RS15815	COG2111	Na H antiporter
B9N48_RS15820	COG1006	Multisubunit Na H antiporter MnhC subunit
B9N48_RS15825	COG0651	ATP synthesis coupled electron transport
B9N48_RS15830	COG1863	multisubunit Na H antiporter MnhE subunit
B9N48_RS15835	COG2212	antiporter activity
B9N48_RS15840	COG1320	monovalent cation:proton antiporter activity
B9N48_RS15845	COG2050	protein possibly involved in aromatic compounds catabolism
B9N48_RS15850	COG2197	response regulator
B9N48_RS15855	COG4585	Histidine kinase
B9N48_RS15865	COG0142	geranyltranstransferase activity
B9N48_RS15880	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
B9N48_RS15885	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B9N48_RS15890	COG1335	isochorismatase
B9N48_RS15895	COG5506	Protein of unknown function (DUF1694)
B9N48_RS15910	COG0628	permease
B9N48_RS15925	COG1418	mRNA catabolic process
B9N48_RS15930	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS15945	COG0433	COG0433 Predicted ATPase
B9N48_RS15945	COG1674	ftsk spoiiie
B9N48_RS15950	COG4499	WXG100 protein secretion system (Wss), protein YukC
B9N48_RS15955	COG5417	Belongs to the EsaB family
B9N48_RS15960	COG4842	Belongs to the WXG100 family
B9N48_RS15970	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B9N48_RS15970	COG2508	Transcriptional regulator
B9N48_RS15975	COG0686	Belongs to the AlaDH PNT family
B9N48_RS15980	COG5634	Uncharacterized conserved protein (DUF2278)
B9N48_RS15985	COG3251	PFAM MbtH domain protein
B9N48_RS15990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9N48_RS15995	COG3433	isochorismatase activity
B9N48_RS15995	COG1535	isochorismatase
B9N48_RS16000	COG1021	2,3-dihydroxybenzoate-AMP ligase
B9N48_RS16005	COG1169	isochorismate synthase
B9N48_RS16010	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS16015	COG2819	hydrolase of the alpha beta superfamily
B9N48_RS16020	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B9N48_RS16025	COG1268	BioY protein
B9N48_RS16030	COG2056	Na+-H+ antiporter family
B9N48_RS16035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B9N48_RS16040	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
B9N48_RS16045	COG3584	3D domain protein
B9N48_RS16060	COG1252	NADH dehydrogenase
B9N48_RS16065	COG0492	ferredoxin-NADP+ reductase activity
B9N48_RS16075	COG0516	GMP reductase activity
B9N48_RS16080	COG2808	Putative FMN-binding domain
B9N48_RS16085	COG0456	acetyltransferase
B9N48_RS16090	COG0316	Belongs to the HesB IscA family
B9N48_RS16095	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B9N48_RS16100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B9N48_RS16105	COG4844	belongs to the
B9N48_RS16110	COG1252	NADH dehydrogenase
B9N48_RS16115	COG4837	Protein of unknown function (DUF1462)
B9N48_RS16120	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B9N48_RS16125	COG4946	Tricorn protease homolog
B9N48_RS16125	COG1506	peptidase
B9N48_RS16125	COG0823	Involved in the tonB-independent uptake of proteins
B9N48_RS16130	COG0083	homoserine kinase activity
B9N48_RS16135	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B9N48_RS16140	COG0460	homoserine dehydrogenase
B9N48_RS16145	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B9N48_RS16150	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B9N48_RS16155	COG0647	UMP catabolic process
B9N48_RS16160	COG2445	Protein of unknown function DUF86
B9N48_RS16165	COG4470	Protein conserved in bacteria
B9N48_RS16175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B9N48_RS16180	COG0739	heme binding
B9N48_RS16190	COG3377	Domain of unknown function (DUF1805)
B9N48_RS16195	COG0737	Belongs to the 5'-nucleotidase family
B9N48_RS16200	COG0730	response to heat
B9N48_RS16205	COG1801	Protein of unknown function DUF72
B9N48_RS16215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B9N48_RS16220	COG2508	Transcriptional regulator
B9N48_RS16225	COG2233	PERMEase
B9N48_RS16230	COG2233	PERMEase
B9N48_RS16235	COG3195	allantoin biosynthetic process
B9N48_RS16235	COG3648	Uricase
B9N48_RS16240	COG2351	hydroxyisourate hydrolase activity
B9N48_RS16255	COG2080	2 iron, 2 sulfur cluster binding
B9N48_RS16260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B9N48_RS16265	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B9N48_RS16270	COG2068	MobA-Related Protein
B9N48_RS16275	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B9N48_RS16280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B9N48_RS16285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B9N48_RS16290	COG2356	endonuclease I
B9N48_RS16295	COG3842	ATPase activity
B9N48_RS16300	COG2188	Transcriptional regulator
B9N48_RS16305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9N48_RS16310	COG0395	ABC-type sugar transport system, permease component
B9N48_RS16315	COG1175	transmembrane transport
B9N48_RS16320	COG1653	transport
B9N48_RS16325	COG2222	sugar isomerase
B9N48_RS16330	COG0322	excinuclease ABC activity
B9N48_RS16335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9N48_RS16350	COG0346	lactoylglutathione lyase activity
B9N48_RS16355	COG0640	Transcriptional regulator
B9N48_RS16360	COG0719	Fe-S assembly protein
B9N48_RS16365	COG0822	iron-sulfur transferase activity
B9N48_RS16370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B9N48_RS16375	COG0719	Fe-S assembly protein
B9N48_RS16380	COG0396	ATPase activity
B9N48_RS16395	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B9N48_RS16400	COG1464	Belongs to the NlpA lipoprotein family
B9N48_RS16405	COG2011	ABC-type metal ion transport system permease component
B9N48_RS16410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B9N48_RS16420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9N48_RS16425	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B9N48_RS16435	COG0509	glycine decarboxylation via glycine cleavage system
B9N48_RS16440	COG1393	Belongs to the ArsC family
B9N48_RS16445	COG1960	acyl-CoA dehydrogenase activity
B9N48_RS16450	COG0183	Belongs to the thiolase family
B9N48_RS16455	COG1250	3-hydroxyacyl-CoA dehydrogenase
B9N48_RS16455	COG1024	Enoyl-CoA hydratase
B9N48_RS16475	COG5577	PFAM Coat F domain
B9N48_RS16480	COG1846	Transcriptional regulator
B9N48_RS16485	COG0477	Major facilitator Superfamily
B9N48_RS16490	COG1942	4-Oxalocrotonate Tautomerase
B9N48_RS16495	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS16500	COG0583	DNA-binding transcription factor activity
B9N48_RS16510	COG1120	ATPase activity
B9N48_RS16525	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS16530	COG0783	Belongs to the Dps family
B9N48_RS16535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9N48_RS16540	COG0745	RESPONSE REGULATOR receiver
B9N48_RS16545	COG2205	protein histidine kinase activity
B9N48_RS16545	COG2770	Histidine kinase
B9N48_RS16555	COG1309	transcriptional regulator
B9N48_RS16560	COG0114	fumarate hydratase activity
B9N48_RS16570	COG0697	spore germination
B9N48_RS16575	COG0814	amino acid
B9N48_RS16585	COG2197	response regulator
B9N48_RS16590	COG4585	Histidine kinase
B9N48_RS16595	COG4758	membrane
B9N48_RS16600	COG3595	metallopeptidase activity
B9N48_RS16605	COG1842	Phage shock protein A
B9N48_RS16610	COG4758	membrane
B9N48_RS16615	COG2814	Major facilitator Superfamily
B9N48_RS16620	COG2096	Adenosyltransferase
B9N48_RS16625	COG1120	ATPase activity
B9N48_RS16630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9N48_RS16635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9N48_RS16640	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS16645	COG3386	PFAM SMP-30 Gluconolaconase
B9N48_RS16650	COG2205	protein histidine kinase activity
B9N48_RS16655	COG0745	RESPONSE REGULATOR receiver
B9N48_RS16665	COG1191	sigma factor activity
B9N48_RS16675	COG2140	Oxalate decarboxylase
B9N48_RS16685	COG0577	efflux transmembrane transporter activity
B9N48_RS16690	COG1136	(ABC) transporter
B9N48_RS16695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B9N48_RS16700	COG1120	ATPase activity
B9N48_RS16705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9N48_RS16710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9N48_RS16715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9N48_RS16725	COG0531	amino acid
B9N48_RS16740	COG1988	membrane-bound metal-dependent
B9N48_RS16745	COG1368	sulfuric ester hydrolase activity
B9N48_RS16750	COG1910	domain protein
B9N48_RS16755	COG0725	ABC transporter, periplasmic molybdate-binding protein
B9N48_RS16760	COG4149	molybdate abc transporter
B9N48_RS16765	COG0656	L-ascorbic acid biosynthetic process
B9N48_RS16775	COG0025	NhaP-type Na H and K H
B9N48_RS16780	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B9N48_RS16785	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B9N48_RS16790	COG3973	AAA domain
B9N48_RS16795	COG2860	membrane
B9N48_RS16800	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B9N48_RS16805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B9N48_RS16810	COG2217	Heavy metal translocating P-type atpase
B9N48_RS16815	COG2217	Heavy metal translocating P-type atpase
B9N48_RS16820	COG2608	mercury ion transmembrane transporter activity
B9N48_RS16825	COG1937	Protein conserved in bacteria
B9N48_RS16830	COG0673	inositol 2-dehydrogenase activity
B9N48_RS16835	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B9N48_RS16840	COG1289	transmembrane transporter activity
B9N48_RS16850	COG2076	Multidrug Resistance protein
B9N48_RS16855	COG1309	transcriptional regulator
B9N48_RS16860	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS16870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B9N48_RS16875	COG0557	exoribonuclease II activity
B9N48_RS16880	COG1647	Serine aminopeptidase, S33
B9N48_RS16885	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B9N48_RS16890	COG0596	Alpha beta hydrolase
B9N48_RS16895	COG1476	TRANSCRIPTIONal
B9N48_RS16900	COG1396	sequence-specific DNA binding
B9N48_RS16905	COG1396	sequence-specific DNA binding
B9N48_RS16910	COG1733	regulation of RNA biosynthetic process
B9N48_RS16920	COG1174	glycine betaine transport
B9N48_RS16925	COG1732	Glycine betaine
B9N48_RS16930	COG1174	glycine betaine transport
B9N48_RS16935	COG0517	IMP dehydrogenase activity
B9N48_RS16935	COG1125	glycine betaine transport
B9N48_RS16940	COG1510	regulation of RNA biosynthetic process
B9N48_RS16945	COG1174	glycine betaine transport
B9N48_RS16950	COG1732	Glycine betaine
B9N48_RS16955	COG1174	glycine betaine transport
B9N48_RS16960	COG0517	IMP dehydrogenase activity
B9N48_RS16960	COG1125	glycine betaine transport
B9N48_RS16965	COG1510	regulation of RNA biosynthetic process
B9N48_RS16970	COG2095	MarC family integral membrane protein
B9N48_RS16980	COG3064	Membrane
B9N48_RS16985	COG4640	response to antibiotic
B9N48_RS16990	COG0456	acetyltransferase
B9N48_RS16995	COG0148	phosphopyruvate hydratase activity
B9N48_RS17000	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
B9N48_RS17005	COG0149	triose-phosphate isomerase activity
B9N48_RS17010	COG0126	phosphoglycerate kinase activity
B9N48_RS17015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B9N48_RS17020	COG2390	Transcriptional regulator
B9N48_RS17025	COG2814	Major facilitator Superfamily
B9N48_RS17030	COG1609	Transcriptional regulator
B9N48_RS17035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9N48_RS17045	COG0583	DNA-binding transcription factor activity
B9N48_RS17050	COG0697	spore germination
B9N48_RS17055	COG1113	amino acid transport
B9N48_RS17060	COG3858	chitin binding
B9N48_RS17065	COG1556	Lactate utilization protein
B9N48_RS17070	COG1139	Iron-sulfur cluster binding protein
B9N48_RS17075	COG0247	lactate metabolic process
B9N48_RS17080	COG2197	response regulator
B9N48_RS17085	COG4585	Histidine kinase
B9N48_RS17095	COG1131	(ABC) transporter
B9N48_RS17100	COG0596	Alpha beta hydrolase
B9N48_RS17105	COG2208	phosphoserine phosphatase activity
B9N48_RS17110	COG3867	Arabinogalactan endo-beta-1,4-galactanase
B9N48_RS17115	COG1874	Beta-galactosidase
B9N48_RS17120	COG3833	ABC-type maltose transport systems, permease component
B9N48_RS17125	COG1175	transmembrane transport
B9N48_RS17130	COG2182	Extracellular solute-binding protein
B9N48_RS17135	COG1609	Transcriptional regulator
B9N48_RS17140	COG2186	Transcriptional regulator
B9N48_RS17145	COG1620	l-lactate permease
B9N48_RS17150	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B9N48_RS17160	COG5039	Polysaccharide pyruvyl transferase
B9N48_RS17165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B9N48_RS17170	COG0110	maltose O-acetyltransferase activity
B9N48_RS17175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B9N48_RS17180	COG2244	polysaccharide biosynthetic process
B9N48_RS17185	COG1216	Glycosyl transferase, family 2
B9N48_RS17190	COG5039	Polysaccharide pyruvyl transferase
B9N48_RS17195	COG1216	Glycosyl transferase, family 2
B9N48_RS17205	COG0438	transferase activity, transferring glycosyl groups
B9N48_RS17210	COG1215	transferase activity, transferring glycosyl groups
B9N48_RS17215	COG0438	transferase activity, transferring glycosyl groups
B9N48_RS17220	COG1086	Polysaccharide biosynthesis protein
B9N48_RS17225	COG0489	protein tyrosine kinase activity
B9N48_RS17230	COG3944	biosynthesis protein
B9N48_RS17235	COG1396	sequence-specific DNA binding
B9N48_RS17240	COG2272	Belongs to the type-B carboxylesterase lipase family
B9N48_RS17250	COG3479	Phenolic acid decarboxylase
B9N48_RS17260	COG1794	racemase activity, acting on amino acids and derivatives
B9N48_RS17265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B9N48_RS17270	COG1621	beta-fructofuranosidase activity
B9N48_RS17275	COG1621	beta-fructofuranosidase activity
B9N48_RS17280	COG0531	amino acid
B9N48_RS17285	COG1309	transcriptional regulator
B9N48_RS17290	COG2076	Multidrug Resistance protein
B9N48_RS17295	COG2076	Multidrug Resistance protein
B9N48_RS17305	COG3621	Patatin-like phospholipase
B9N48_RS17315	COG0740	serine-type endopeptidase activity
B9N48_RS17320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B9N48_RS17325	COG0366	Alpha amylase catalytic
B9N48_RS17330	COG1554	hydrolase, family 65, central catalytic
B9N48_RS17335	COG5521	maltodextrose utilization protein MalA
B9N48_RS17340	COG3833	ABC-type maltose transport systems, permease component
B9N48_RS17345	COG1175	transmembrane transport
B9N48_RS17350	COG2182	Extracellular solute-binding protein
B9N48_RS17355	COG0366	Alpha amylase catalytic
B9N48_RS17360	COG1609	Transcriptional regulator
B9N48_RS17365	COG1611	Belongs to the LOG family
B9N48_RS17370	COG1694	Mazg nucleotide pyrophosphohydrolase
B9N48_RS17375	COG0659	secondary active sulfate transmembrane transporter activity
B9N48_RS17380	COG0288	reversible hydration of carbon dioxide
B9N48_RS17385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B9N48_RS17390	COG0577	efflux transmembrane transporter activity
B9N48_RS17395	COG1136	(ABC) transporter
B9N48_RS17400	COG5002	protein histidine kinase activity
B9N48_RS17405	COG0745	RESPONSE REGULATOR receiver
B9N48_RS17415	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B9N48_RS17420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9N48_RS17425	COG1481	regulation of sporulation
B9N48_RS17430	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B9N48_RS17435	COG1660	Displays ATPase and GTPase activities
B9N48_RS17440	COG1051	belongs to the nudix hydrolase family
B9N48_RS17445	COG0492	ferredoxin-NADP+ reductase activity
B9N48_RS17450	COG0791	NLP P60 protein
B9N48_RS17450	COG3883	PFAM NLP P60 protein
B9N48_RS17455	COG0457	Tetratricopeptide repeat
B9N48_RS17460	COG1132	(ABC) transporter
B9N48_RS17475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B9N48_RS17475	COG0140	phosphoribosyl-ATP diphosphatase activity
B9N48_RS17480	COG0107	imidazoleglycerol-phosphate synthase activity
B9N48_RS17485	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B9N48_RS17490	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B9N48_RS17495	COG0131	Imidazoleglycerol-phosphate dehydratase
B9N48_RS17500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B9N48_RS17505	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B9N48_RS17510	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B9N48_RS17515	COG4990	cell redox homeostasis
B9N48_RS17520	COG5297	Belongs to the glycosyl hydrolase family 6
B9N48_RS17525	COG0110	maltose O-acetyltransferase activity
B9N48_RS17530	COG0546	phosphoglycolate phosphatase activity
B9N48_RS17535	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B9N48_RS17540	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B9N48_RS17545	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B9N48_RS17550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B9N48_RS17555	COG0363	glucosamine-6-phosphate deaminase activity
B9N48_RS17560	COG2188	Transcriptional regulator
B9N48_RS17565	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B9N48_RS17570	COG1950	PFAM Membrane protein of
B9N48_RS17575	COG1983	PspC domain protein
B9N48_RS17580	COG3595	metallopeptidase activity
B9N48_RS17595	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B9N48_RS17600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B9N48_RS17605	COG0556	nucleotide-excision repair
B9N48_RS17610	COG4897	Protein conserved in bacteria
B9N48_RS17615	COG0574	Belongs to the PEP-utilizing enzyme family
B9N48_RS17615	COG3848	Pyruvate phosphate dikinase
B9N48_RS17620	COG1309	transcriptional regulator
B9N48_RS17625	COG2814	Major facilitator Superfamily
B9N48_RS17630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9N48_RS17640	COG3409	Peptidoglycan-binding domain 1 protein
B9N48_RS17640	COG0793	Belongs to the peptidase S41A family
B9N48_RS17645	COG2177	Part of the ABC transporter FtsEX involved in
B9N48_RS17650	COG2884	Cell division ATP-binding protein ftsE
B9N48_RS17655	COG2010	Cytochrome c
B9N48_RS17660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B9N48_RS17670	COG0653	protein targeting
B9N48_RS17675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B9N48_RS17690	COG1516	flagellar protein fliS
B9N48_RS17695	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B9N48_RS17700	COG1334	flagellar protein FlaG
B9N48_RS17705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B9N48_RS17710	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B9N48_RS17715	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
B9N48_RS17725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B9N48_RS17730	COG4786	Flagellar basal body rod
B9N48_RS17730	COG1256	bacterial-type flagellum assembly
B9N48_RS17735	COG3418	PFAM FlgN family protein
B9N48_RS17740	COG2747	anti-sigma28 factor FlgM
B9N48_RS17750	COG1040	competence protein
B9N48_RS17760	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B9N48_RS17765	COG1307	EDD domain protein, DegV family
B9N48_RS17770	COG2197	response regulator
B9N48_RS17775	COG4585	Histidine kinase
B9N48_RS17780	COG1739	Uncharacterized protein family UPF0029
B9N48_RS17785	COG1316	TRANSCRIPTIONal
B9N48_RS17790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B9N48_RS17795	COG0438	transferase activity, transferring glycosyl groups
B9N48_RS17800	COG1215	transferase activity, transferring glycosyl groups
B9N48_RS17805	COG3206	protein involved in exopolysaccharide biosynthesis
B9N48_RS17810	COG3307	-O-antigen
B9N48_RS17815	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B9N48_RS17820	COG0438	transferase activity, transferring glycosyl groups
B9N48_RS17820	COG0297	glycogen (starch) synthase activity
B9N48_RS17825	COG2244	polysaccharide biosynthetic process
B9N48_RS17830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B9N48_RS17845	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B9N48_RS17850	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B9N48_RS17855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B9N48_RS17860	COG1134	teichoic acid transport
B9N48_RS17865	COG1682	transport, permease protein
B9N48_RS17870	COG4193	domain, Protein
B9N48_RS17875	COG1482	cell wall glycoprotein biosynthetic process
B9N48_RS17880	COG0697	spore germination
B9N48_RS17885	COG0814	amino acid
B9N48_RS17895	COG2814	Major facilitator Superfamily
B9N48_RS17900	COG1316	TRANSCRIPTIONal
B9N48_RS17905	COG0561	phosphatase activity
B9N48_RS17910	COG0791	NLP P60 protein
B9N48_RS17920	COG2843	Capsule synthesis protein
B9N48_RS17930	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B9N48_RS17940	COG1609	Transcriptional regulator
B9N48_RS17945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9N48_RS17950	COG1869	D-ribose catabolic process
B9N48_RS17955	COG1129	ABC transporter
B9N48_RS17960	COG1172	Belongs to the binding-protein-dependent transport system permease family
B9N48_RS17965	COG1879	ABC-type sugar transport system periplasmic component
B9N48_RS17970	COG3103	Sh3 type 3 domain protein
B9N48_RS17980	COG2249	NAD(P)H dehydrogenase (quinone) activity
B9N48_RS17985	COG3527	Alpha-acetolactate decarboxylase
B9N48_RS17990	COG0028	Belongs to the TPP enzyme family
B9N48_RS17995	COG0583	DNA-binding transcription factor activity
B9N48_RS18000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B9N48_RS18015	COG5337	Spore coat protein CotH
B9N48_RS18025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B9N48_RS18035	COG0405	Gamma-glutamyltransferase
B9N48_RS18040	COG1522	sequence-specific DNA binding
B9N48_RS18045	COG2059	Chromate
B9N48_RS18050	COG2059	Chromate
B9N48_RS18060	COG0655	NAD(P)H dehydrogenase (quinone) activity
B9N48_RS18065	COG0583	DNA-binding transcription factor activity
B9N48_RS18070	COG1515	deoxyribonuclease V activity
B9N48_RS18075	COG2849	repeat protein
B9N48_RS18080	COG5444	nuclease activity
B9N48_RS18095	COG3878	Protein conserved in bacteria
B9N48_RS18100	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B9N48_RS18105	COG4464	protein tyrosine phosphatase activity
B9N48_RS18110	COG0489	protein tyrosine kinase activity
B9N48_RS18115	COG3944	biosynthesis protein
B9N48_RS18125	COG4715	Zinc finger, swim domain protein
B9N48_RS18130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B9N48_RS18135	COG0561	phosphatase activity
B9N48_RS18140	COG1349	DNA-binding transcription factor activity
B9N48_RS18145	COG0629	single-stranded DNA binding
B9N48_RS18160	COG3764	Sortase (surface protein transpeptidase)
B9N48_RS18165	COG0745	RESPONSE REGULATOR receiver
B9N48_RS18165	COG2972	Histidine kinase
B9N48_RS18170	COG1970	mechanosensitive ion channel activity
B9N48_RS18175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B9N48_RS18180	COG0457	Tetratricopeptide repeat
B9N48_RS18185	COG4786	Flagellar basal body rod
B9N48_RS18190	COG4786	Flagellar basal body rod
B9N48_RS18195	COG1077	Cell shape determining protein MreB Mrl
B9N48_RS18200	COG1609	Transcriptional regulator
B9N48_RS18210	COG1846	Transcriptional regulator
B9N48_RS18215	COG2814	Major facilitator Superfamily
B9N48_RS18220	COG3420	alginic acid biosynthetic process
B9N48_RS18225	COG1953	Uracil, thiamine, allantoin
B9N48_RS18230	COG0477	Major facilitator Superfamily
B9N48_RS18235	COG1335	isochorismatase
B9N48_RS18245	COG0004	ammonium transporteR
B9N48_RS18250	COG0347	Belongs to the P(II) protein family
B9N48_RS18255	COG0671	phosphoesterase, PA-phosphatase related
B9N48_RS18265	COG0739	heme binding
B9N48_RS18270	COG1247	-acetyltransferase
B9N48_RS18285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B9N48_RS18290	COG0789	Transcriptional regulator
B9N48_RS18300	COG2910	NAD(P)H-binding
B9N48_RS18305	COG1959	2 iron, 2 sulfur cluster binding
B9N48_RS18310	COG0804	urea catabolic process
B9N48_RS18315	COG0832	Belongs to the urease beta subunit family
B9N48_RS18320	COG0831	urea catabolic process
B9N48_RS18330	COG3237	CsbD-like
B9N48_RS18335	COG1994	Peptidase M50
B9N48_RS18340	COG0457	Tetratricopeptide repeat
B9N48_RS18350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B9N48_RS18355	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B9N48_RS18365	COG2304	oxidoreductase activity
B9N48_RS18375	COG2304	oxidoreductase activity
B9N48_RS18380	COG2385	sporulation resulting in formation of a cellular spore
B9N48_RS18385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B9N48_RS18395	COG4836	Membrane
B9N48_RS18405	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B9N48_RS18410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B9N48_RS18415	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B9N48_RS18420	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B9N48_RS18425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B9N48_RS18430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B9N48_RS18440	COG0356	it plays a direct role in the translocation of protons across the membrane
B9N48_RS18450	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B9N48_RS18455	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B9N48_RS18460	COG4475	Protein of unknown function (DUF436)
B9N48_RS18465	COG0698	ribose 5-phosphate isomerase
B9N48_RS18470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B9N48_RS18475	COG1971	Probably functions as a manganese efflux pump
B9N48_RS18480	COG0009	L-threonylcarbamoyladenylate synthase
B9N48_RS18485	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B9N48_RS18505	COG2890	protein-(glutamine-N5) methyltransferase activity
B9N48_RS18510	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B9N48_RS18515	COG0346	lactoylglutathione lyase activity
B9N48_RS18520	COG0789	Transcriptional regulator
B9N48_RS18525	COG0679	Auxin Efflux Carrier
B9N48_RS18530	COG0281	malic enzyme
B9N48_RS18535	COG1435	thymidine kinase activity
B9N48_RS18545	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B9N48_RS18550	COG1494	fructose-1,6-bisphosphatase
B9N48_RS18555	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B9N48_RS18560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B9N48_RS18565	COG0191	fructose-bisphosphate aldolase activity
B9N48_RS18570	COG2204	response regulator
B9N48_RS18575	COG4821	SIS domain
B9N48_RS18580	COG0504	CTP synthase activity
B9N48_RS18585	COG3343	RNA polymerase activity
B9N48_RS18590	COG1960	acyl-CoA dehydrogenase activity
B9N48_RS18595	COG2181	nitrate reductase activity
B9N48_RS18595	COG0247	lactate metabolic process
B9N48_RS18600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B9N48_RS18605	COG4294	response to UV
B9N48_RS18615	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B9N48_RS18620	COG1132	(ABC) transporter
B9N48_RS18625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B9N48_RS18635	COG2181	nitrate reductase activity
B9N48_RS18640	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B9N48_RS18645	COG1140	nitrate reductase beta subunit
B9N48_RS18650	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B9N48_RS18655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B9N48_RS18665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B9N48_RS18670	COG2223	nitrite transmembrane transporter activity
B9N48_RS18675	COG0018	arginyl-trna synthetase
B9N48_RS18680	COG4506	Protein conserved in bacteria
B9N48_RS18695	COG0535	radical SAM domain protein
B9N48_RS18705	COG1131	(ABC) transporter
B9N48_RS18710	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B9N48_RS18715	COG0612	Peptidase, M16
B9N48_RS18720	COG0612	Peptidase, M16
B9N48_RS18730	COG3391	amine dehydrogenase activity
B9N48_RS18735	COG3391	amine dehydrogenase activity
B9N48_RS18745	COG0457	Tetratricopeptide repeat
B9N48_RS18760	COG0010	Belongs to the arginase family
B9N48_RS18765	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B9N48_RS18770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B9N48_RS18785	COG1994	Peptidase M50
B9N48_RS18790	COG1942	4-Oxalocrotonate Tautomerase
B9N48_RS18795	COG1846	Transcriptional regulator
B9N48_RS18800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B9N48_RS18805	COG0477	Major facilitator Superfamily
B9N48_RS18810	COG1959	2 iron, 2 sulfur cluster binding
B9N48_RS18815	COG3465	dGTPase activity
B9N48_RS18820	COG1078	dGTPase activity
B9N48_RS18825	COG4844	belongs to the
B9N48_RS18835	COG0697	spore germination
B9N48_RS18840	COG0095	Lipoate-protein ligase
B9N48_RS18845	COG0583	DNA-binding transcription factor activity
B9N48_RS18850	COG0280	phosphate acetyltransferase
B9N48_RS18855	COG3253	May function as heme-dependent peroxidase
B9N48_RS18860	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS18865	COG0436	Aminotransferase
B9N48_RS18870	COG2814	Major facilitator Superfamily
B9N48_RS18875	COG0151	Belongs to the GarS family
B9N48_RS18880	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS18885	COG1917	Cupin 2, conserved barrel domain protein
B9N48_RS18890	COG0077	Prephenate dehydratase
B9N48_RS18895	COG2814	Major facilitator Superfamily
B9N48_RS18900	COG0833	amino acid
B9N48_RS18905	COG4187	Peptidase family M20/M25/M40
B9N48_RS18910	COG1012	belongs to the aldehyde dehydrogenase family
B9N48_RS18915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B9N48_RS18925	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
B9N48_RS18930	COG1091	dTDP-4-dehydrorhamnose reductase activity
B9N48_RS18935	COG1088	dTDP-glucose 4,6-dehydratase activity
B9N48_RS18940	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B9N48_RS18945	COG3980	spore coat polysaccharide biosynthesis protein
B9N48_RS18950	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
B9N48_RS18955	COG2089	acid synthase
B9N48_RS18960	COG0456	acetyltransferase
B9N48_RS18965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B9N48_RS18970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B9N48_RS18975	COG0463	Glycosyl transferase, family 2
B9N48_RS18990	COG2363	Small membrane protein
B9N48_RS18995	COG2233	PERMEase
B9N48_RS19005	COG1012	belongs to the aldehyde dehydrogenase family
B9N48_RS19010	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B9N48_RS19015	COG1216	Glycosyl transferase, family 2
B9N48_RS19020	COG0351	phosphomethylpyrimidine kinase
B9N48_RS19030	COG1621	beta-fructofuranosidase activity
B9N48_RS19035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9N48_RS19035	COG1263	PTS System
B9N48_RS19040	COG2116	formate transmembrane transporter activity
B9N48_RS19045	COG3711	transcriptional antiterminator
B9N48_RS19055	COG1404	Belongs to the peptidase S8 family
B9N48_RS19060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9N48_RS19065	COG0778	Nitroreductase
B9N48_RS19070	COG0772	Belongs to the SEDS family
B9N48_RS19080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B9N48_RS19085	COG1845	cytochrome c oxidase, subunit III
B9N48_RS19090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B9N48_RS19095	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B9N48_RS19100	COG2261	transglycosylase associated protein
B9N48_RS19105	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
B9N48_RS19110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
B9N48_RS19115	COG2246	polysaccharide biosynthetic process
B9N48_RS19120	COG1309	transcriptional regulator
B9N48_RS19130	COG3162	membrane
B9N48_RS19135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9N48_RS19140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B9N48_RS19145	COG2837	iron assimilation
B9N48_RS19150	COG2822	iron ion transport
B9N48_RS19155	COG0672	)-iron permease
B9N48_RS19160	COG0352	thiamine-phosphate diphosphorylase activity
B9N48_RS19165	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
B9N48_RS19170	COG0583	DNA-binding transcription factor activity
B9N48_RS19175	COG1380	Effector of murein hydrolase LrgA
B9N48_RS19180	COG1346	cytolysis
B9N48_RS19185	COG2814	Major facilitator Superfamily
B9N48_RS19190	COG4895	conserved protein (DUF2196)
B9N48_RS19195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B9N48_RS19200	COG0346	lactoylglutathione lyase activity
B9N48_RS19215	COG1404	Belongs to the peptidase S8 family
B9N48_RS19220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9N48_RS19220	COG1263	PTS System
B9N48_RS19225	COG3711	transcriptional antiterminator
B9N48_RS19230	COG1442	glycosyl transferase family 8
B9N48_RS19235	COG5522	Integral membrane protein (intg_mem_TP0381)
B9N48_RS19240	COG1846	Transcriptional regulator
B9N48_RS19245	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B9N48_RS19250	COG2234	aminopeptidase activity
B9N48_RS19255	COG2357	RelA SpoT domain protein
B9N48_RS19260	COG1575	Belongs to the MenA family. Type 1 subfamily
B9N48_RS19270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B9N48_RS19275	COG1696	Membrane protein involved in D-alanine export
B9N48_RS19280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B9N48_RS19285	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
B9N48_RS19290	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
B9N48_RS19295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B9N48_RS19300	COG1486	melibiose metabolic process
B9N48_RS19305	COG1447	Phosphotransferase system cellobiose-specific component IIA
B9N48_RS19310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B9N48_RS19315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B9N48_RS19320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B9N48_RS19320	COG3711	transcriptional antiterminator
B9N48_RS19330	COG2094	Belongs to the DNA glycosylase MPG family
B9N48_RS19335	COG0753	catalase activity
B9N48_RS19340	COG2814	Major facilitator Superfamily
B9N48_RS19345	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B9N48_RS19350	COG1131	(ABC) transporter
B9N48_RS19370	COG1595	DNA-templated transcription, initiation
B9N48_RS19375	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B9N48_RS19380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B9N48_RS19385	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B9N48_RS19390	COG4988	ABC transporter
B9N48_RS19395	COG1294	oxidase, subunit
B9N48_RS19400	COG1271	oxidase subunit
B9N48_RS19405	COG3493	citrate carrier protein
B9N48_RS19410	COG0501	Belongs to the peptidase M48B family
B9N48_RS19420	COG0726	polysaccharide deacetylase
B9N48_RS19425	COG3842	ATPase activity
B9N48_RS19430	COG2508	Transcriptional regulator
B9N48_RS19435	COG1012	belongs to the aldehyde dehydrogenase family
B9N48_RS19440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B9N48_RS19450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B9N48_RS19460	COG4585	Histidine kinase
B9N48_RS19465	COG2197	response regulator
B9N48_RS19470	COG2195	Cleaves the N-terminal amino acid of tripeptides
B9N48_RS19480	COG4894	glucomannan catabolic process
B9N48_RS19485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B9N48_RS19490	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B9N48_RS19495	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS19500	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B9N48_RS19505	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B9N48_RS19510	COG2610	gluconate transmembrane transporter activity
B9N48_RS19515	COG0500	methyltransferase
B9N48_RS19520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B9N48_RS19535	COG0693	protein deglycase activity
B9N48_RS19535	COG0753	catalase activity
B9N48_RS19540	COG2851	Citrate transporter
B9N48_RS19545	COG2273	Hydrolase Family 16
B9N48_RS19550	COG3711	transcriptional antiterminator
B9N48_RS19560	COG2270	Major facilitator Superfamily
B9N48_RS19565	COG0513	Belongs to the DEAD box helicase family
B9N48_RS19570	COG3401	FG-GAP repeat protein
B9N48_RS19570	COG2755	lipolytic protein G-D-S-L family
B9N48_RS19625	COG3209	COG3209 Rhs family protein
B9N48_RS19630	COG0697	spore germination
B9N48_RS19635	COG0589	response to stress
B9N48_RS19640	COG2723	6-phospho-beta-galactosidase activity
B9N48_RS19650	COG5444	nuclease activity
B9N48_RS19665	COG3507	Belongs to the glycosyl hydrolase 43 family
B9N48_RS19680	COG2986	histidine ammonia-lyase
B9N48_RS19685	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B9N48_RS19690	COG1228	amidohydrolase
B9N48_RS19695	COG0010	Belongs to the arginase family
B9N48_RS19700	COG0833	amino acid
B9N48_RS19705	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B9N48_RS19710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B9N48_RS19715	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B9N48_RS19720	COG2390	Transcriptional regulator
B9N48_RS19730	COG3192	ethanolamine utilization protein
B9N48_RS19735	COG2079	MmgE PrpD family protein
B9N48_RS19740	COG1473	amidohydrolase
B9N48_RS19745	COG1126	abc transporter atp-binding protein
B9N48_RS19750	COG0765	amino acid transport
B9N48_RS19755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B9N48_RS19760	COG0456	acetyltransferase
B9N48_RS19765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B9N48_RS19770	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
B9N48_RS19775	COG0561	phosphatase activity
B9N48_RS19805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9N48_RS19810	COG5294	Protein conserved in bacteria
B9N48_RS19815	COG0577	efflux transmembrane transporter activity
B9N48_RS19820	COG1136	(ABC) transporter
B9N48_RS19825	COG2205	protein histidine kinase activity
B9N48_RS19830	COG0745	RESPONSE REGULATOR receiver
B9N48_RS19835	COG0191	fructose-bisphosphate aldolase activity
B9N48_RS19840	COG1082	Xylose isomerase domain protein TIM barrel
B9N48_RS19845	COG1082	Xylose isomerase domain protein TIM barrel
B9N48_RS19850	COG0673	inositol 2-dehydrogenase activity
B9N48_RS19855	COG2814	Major facilitator Superfamily
B9N48_RS19860	COG1082	Xylose isomerase domain protein TIM barrel
B9N48_RS19865	COG3962	Belongs to the TPP enzyme family
B9N48_RS19870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B9N48_RS19880	COG1012	belongs to the aldehyde dehydrogenase family
B9N48_RS19885	COG1349	DNA-binding transcription factor activity
B9N48_RS19890	COG0667	Aldo Keto reductase
B9N48_RS19905	COG2814	Major facilitator Superfamily
B9N48_RS19910	COG0326	Molecular chaperone. Has ATPase activity
B9N48_RS19920	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS19925	COG1309	transcriptional regulator
B9N48_RS19930	COG1012	belongs to the aldehyde dehydrogenase family
B9N48_RS19940	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B9N48_RS19950	COG1714	RDD family
B9N48_RS19955	COG2311	Membrane
B9N48_RS19960	COG1917	Cupin 2, conserved barrel domain protein
B9N48_RS19965	COG1309	transcriptional regulator
B9N48_RS19970	COG1028	Short-chain dehydrogenase reductase Sdr
B9N48_RS19975	COG1846	Transcriptional regulator
B9N48_RS19980	COG1380	Effector of murein hydrolase LrgA
B9N48_RS19985	COG1346	cytolysis
B9N48_RS19990	COG5039	Polysaccharide pyruvyl transferase
B9N48_RS19995	COG1929	Belongs to the glycerate kinase type-1 family
B9N48_RS20000	COG1802	Transcriptional regulator
B9N48_RS20005	COG1070	Carbohydrate kinase
B9N48_RS20010	COG2610	gluconate transmembrane transporter activity
B9N48_RS20015	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B9N48_RS20020	COG0450	alkyl hydroperoxide reductase
B9N48_RS20025	COG3634	alkyl hydroperoxide reductase activity
B9N48_RS20030	COG2723	6-phospho-beta-galactosidase activity
B9N48_RS20040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B9N48_RS20040	COG2190	(PTS) system
B9N48_RS20040	COG1263	PTS System
B9N48_RS20045	COG2188	Transcriptional regulator
B9N48_RS20060	COG1131	(ABC) transporter
B9N48_RS20065	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
B9N48_RS20070	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B9N48_RS20085	COG1063	alcohol dehydrogenase
B9N48_RS20105	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
B9N48_RS20110	COG0456	acetyltransferase
B9N48_RS20115	COG0457	Tetratricopeptide repeat
B9N48_RS20125	COG0010	Belongs to the arginase family
B9N48_RS20130	COG0833	amino acid
B9N48_RS20135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B9N48_RS20140	COG3829	transcription factor binding
B9N48_RS20145	COG5002	protein histidine kinase activity
B9N48_RS20150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9N48_RS20155	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B9N48_RS20160	COG4853	Protein conserved in bacteria
B9N48_RS20165	COG4863	YycH protein
B9N48_RS20170	COG5002	protein histidine kinase activity
B9N48_RS20175	COG0745	RESPONSE REGULATOR receiver
B9N48_RS20205	COG0346	lactoylglutathione lyase activity
B9N48_RS20210	COG0305	Participates in initiation and elongation during chromosome replication
B9N48_RS20225	COG3093	addiction module antidote protein HigA
B9N48_RS20230	COG2807	transmembrane transport
B9N48_RS20235	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B9N48_RS20240	COG0359	binds to the 23S rRNA
B9N48_RS20245	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
B9N48_RS20250	COG4241	membrane
B9N48_RS20260	COG5577	PFAM Coat F domain
B9N48_RS20265	COG1733	regulation of RNA biosynthetic process
B9N48_RS20270	COG1227	inorganic diphosphatase activity
B9N48_RS20285	COG2271	Major facilitator Superfamily
B9N48_RS20300	COG4319	ketosteroid isomerase
B9N48_RS20305	COG1357	PFAM Pentapeptide repeats (8 copies)
B9N48_RS20310	COG2814	Major facilitator Superfamily
B9N48_RS20315	COG0583	DNA-binding transcription factor activity
B9N48_RS20320	COG2153	protein acetylation
B9N48_RS20330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9N48_RS20335	COG1846	Transcriptional regulator
B9N48_RS20340	COG2153	protein acetylation
B9N48_RS20345	COG2364	Membrane
B9N48_RS20350	COG0456	acetyltransferase
B9N48_RS20355	COG2315	Protein conserved in bacteria
B9N48_RS20360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B9N48_RS20370	COG2814	Major facilitator Superfamily
B9N48_RS20375	COG1331	Highly conserved protein containing a thioredoxin domain
B9N48_RS20380	COG0789	Transcriptional regulator
B9N48_RS20385	COG0697	spore germination
B9N48_RS20390	COG1331	Highly conserved protein containing a thioredoxin domain
B9N48_RS20395	COG1266	CAAX protease self-immunity
B9N48_RS20400	COG2814	Major facilitator Superfamily
B9N48_RS20400	COG0477	Major facilitator Superfamily
B9N48_RS20405	COG0110	maltose O-acetyltransferase activity
B9N48_RS20410	COG0346	lactoylglutathione lyase activity
B9N48_RS20415	COG1609	Transcriptional regulator
B9N48_RS20420	COG0708	Exodeoxyribonuclease III
B9N48_RS20425	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B9N48_RS20430	COG0629	single-stranded DNA binding
B9N48_RS20435	COG0360	Binds together with S18 to 16S ribosomal RNA
B9N48_RS20440	COG0012	GTP binding
B9N48_RS20445	COG0243	molybdopterin cofactor binding
B9N48_RS20450	COG4481	Protein conserved in bacteria
B9N48_RS20455	COG3949	Membrane
B9N48_RS20465	COG1475	DNA binding
B9N48_RS20470	COG1192	Involved in chromosome partitioning
B9N48_RS20480	COG1475	DNA binding
B9N48_RS20485	COG0357	Ribosomal RNA small subunit methyltransferase G
B9N48_RS20490	COG0445	tRNA wobble uridine modification
B9N48_RS20495	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B9N48_RS20500	COG1847	R3H domain protein
B9N48_RS20505	COG0706	membrane insertase activity
B9N48_RS20510	COG0594	ribonuclease P activity