locus-tag	class	description
BKN48_RS00010	COG1366	Belongs to the anti-sigma-factor antagonist family
BKN48_RS00015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKN48_RS00020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKN48_RS00030	COG2962	Rard protein
BKN48_RS00050	COG1942	4-Oxalocrotonate Tautomerase
BKN48_RS00055	COG1733	regulation of RNA biosynthetic process
BKN48_RS00060	COG0778	Nitroreductase
BKN48_RS00065	COG0400	carboxylic ester hydrolase activity
BKN48_RS00070	COG0346	lactoylglutathione lyase activity
BKN48_RS00080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKN48_RS00085	COG3409	Peptidoglycan-binding domain 1 protein
BKN48_RS00085	COG0793	Belongs to the peptidase S41A family
BKN48_RS00090	COG2226	methyltransferase
BKN48_RS00100	COG1876	peptidase activity
BKN48_RS00105	COG0813	purine-nucleoside phosphorylase activity
BKN48_RS00120	COG0671	phosphoesterase, PA-phosphatase related
BKN48_RS00145	COG4479	Belongs to the UPF0346 family
BKN48_RS00155	COG1509	lysine 2,3-aminomutase activity
BKN48_RS00160	COG0456	acetyltransferase
BKN48_RS00165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKN48_RS00170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BKN48_RS00175	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BKN48_RS00180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKN48_RS00195	COG0456	acetyltransferase
BKN48_RS00200	COG0463	Glycosyl transferase, family 2
BKN48_RS00215	COG4641	Protein conserved in bacteria
BKN48_RS00220	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BKN48_RS00225	COG1086	Polysaccharide biosynthesis protein
BKN48_RS00230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKN48_RS00235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKN48_RS00240	COG1846	Transcriptional regulator
BKN48_RS00245	COG0534	Mate efflux family protein
BKN48_RS00255	COG4698	Protein conserved in bacteria
BKN48_RS00260	COG2755	lipolytic protein G-D-S-L family
BKN48_RS00265	COG1999	signal sequence binding
BKN48_RS00280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKN48_RS00285	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BKN48_RS00290	COG1272	protein, Hemolysin III
BKN48_RS00295	COG0204	Acyl-transferase
BKN48_RS00300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKN48_RS00305	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BKN48_RS00315	COG2136	Putative SAM-dependent methyltransferase
BKN48_RS00315	COG2521	methyltransferase
BKN48_RS00325	COG0129	dihydroxy-acid dehydratase activity
BKN48_RS00330	COG1413	lyase activity
BKN48_RS00335	COG1418	mRNA catabolic process
BKN48_RS00340	COG0386	Belongs to the glutathione peroxidase family
BKN48_RS00345	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BKN48_RS00350	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKN48_RS00355	COG1278	Cold shock
BKN48_RS00375	COG0328	RNA-DNA hybrid ribonuclease activity
BKN48_RS00380	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BKN48_RS00385	COG0328	RNA-DNA hybrid ribonuclease activity
BKN48_RS00395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKN48_RS00415	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BKN48_RS00420	COG1755	Isoprenylcysteine carboxyl methyltransferase
BKN48_RS00425	COG3424	synthase
BKN48_RS00430	COG2233	PERMEase
BKN48_RS00435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKN48_RS00440	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BKN48_RS00450	COG0800	Aldolase
BKN48_RS00455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKN48_RS00460	COG1609	Transcriptional regulator
BKN48_RS00465	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BKN48_RS00470	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS00475	COG1199	ATP-dependent helicase activity
BKN48_RS00485	COG0116	Belongs to the methyltransferase superfamily
BKN48_RS00500	COG4474	Belongs to the UPF0398 family
BKN48_RS00510	COG3359	exonuclease
BKN48_RS00515	COG1205	dead DEAH box helicase
BKN48_RS00515	COG1111	helicase
BKN48_RS00520	COG2190	(PTS) system
BKN48_RS00525	COG0071	Belongs to the small heat shock protein (HSP20) family
BKN48_RS00560	COG3331	DNA recombination
BKN48_RS00565	COG4499	WXG100 protein secretion system (Wss), protein YukC
BKN48_RS00565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKN48_RS00575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BKN48_RS00580	COG3935	DnaD domain protein
BKN48_RS00585	COG0017	Asparaginyl-tRNA synthetase
BKN48_RS00590	COG0436	Aminotransferase
BKN48_RS00595	COG5353	protein conserved in bacteria
BKN48_RS00605	COG1199	ATP-dependent helicase activity
BKN48_RS00605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BKN48_RS00610	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BKN48_RS00615	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BKN48_RS00620	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BKN48_RS00625	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BKN48_RS00625	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BKN48_RS00630	COG0617	tRNA 3'-terminal CCA addition
BKN48_RS00635	COG0438	transferase activity, transferring glycosyl groups
BKN48_RS00640	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKN48_RS00645	COG1803	Methylglyoxal synthase
BKN48_RS00650	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BKN48_RS00655	COG1694	Mazg nucleotide pyrophosphohydrolase
BKN48_RS00660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKN48_RS00670	COG4347	Protein of unknown function (DUF1405)
BKN48_RS00675	COG2010	Cytochrome c
BKN48_RS00675	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKN48_RS00680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKN48_RS00685	COG0723	plastoquinol--plastocyanin reductase activity
BKN48_RS00695	COG5582	Belongs to the UPF0302 family
BKN48_RS00700	COG0457	Tetratricopeptide repeat
BKN48_RS00705	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BKN48_RS00710	COG0287	Prephenate dehydrogenase
BKN48_RS00720	COG0159	tryptophan synthase activity
BKN48_RS00725	COG0133	tryptophan synthase activity
BKN48_RS00730	COG0135	phosphoribosylanthranilate isomerase activity
BKN48_RS00740	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BKN48_RS00745	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BKN48_RS00750	COG4401	Chorismate mutase type I
BKN48_RS00755	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BKN48_RS00760	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BKN48_RS00765	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BKN48_RS00775	COG0105	UTP biosynthetic process
BKN48_RS00780	COG0142	geranyltranstransferase activity
BKN48_RS00785	COG2226	methyltransferase
BKN48_RS00790	COG0142	geranyltranstransferase activity
BKN48_RS00800	COG0302	gtp cyclohydrolase
BKN48_RS00805	COG0776	regulation of translation
BKN48_RS00810	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BKN48_RS00825	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BKN48_RS00830	COG1160	GTP binding
BKN48_RS00855	COG1304	FMN binding
BKN48_RS00860	COG0539	negative regulation of cytoplasmic translation
BKN48_RS00865	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BKN48_RS00875	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BKN48_RS00880	COG2959	enzyme of heme biosynthesis
BKN48_RS00885	COG3409	Peptidoglycan-binding domain 1 protein
BKN48_RS00885	COG3773	Cell wall hydrolase
BKN48_RS00890	COG2339	peptidase activity
BKN48_RS00895	COG0492	ferredoxin-NADP+ reductase activity
BKN48_RS00900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKN48_RS00905	COG4862	establishment of competence for transformation
BKN48_RS00910	COG1408	metallophosphoesterase
BKN48_RS00920	COG1388	LysM domain
BKN48_RS00925	COG1266	CAAX protease self-immunity
BKN48_RS00930	COG0514	ATP-dependent DNA helicase (RecQ)
BKN48_RS00935	COG4955	Helix-turn-helix domain
BKN48_RS00940	COG1141	Ferredoxin
BKN48_RS00945	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BKN48_RS00950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKN48_RS00955	COG0710	3-dehydroquinate dehydratase activity
BKN48_RS00965	COG1595	DNA-templated transcription, initiation
BKN48_RS00970	COG5002	protein histidine kinase activity
BKN48_RS00975	COG0745	RESPONSE REGULATOR receiver
BKN48_RS00980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKN48_RS00985	COG1333	cytochrome c biogenesis protein
BKN48_RS00990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKN48_RS00995	COG1187	pseudouridine synthase activity
BKN48_RS01000	COG0700	Nucleoside recognition
BKN48_RS01005	COG2715	membrane protein required for spore maturation
BKN48_RS01010	COG1686	Belongs to the peptidase S11 family
BKN48_RS01020	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BKN48_RS01025	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BKN48_RS01030	COG1547	Domain of unknown function (DUF309)
BKN48_RS01035	COG0456	acetyltransferase
BKN48_RS01040	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BKN48_RS01045	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKN48_RS01045	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKN48_RS01050	COG0307	riboflavin synthase, alpha
BKN48_RS01055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKN48_RS01055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKN48_RS01065	COG0681	Belongs to the peptidase S26 family
BKN48_RS01070	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BKN48_RS01080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BKN48_RS01085	COG4086	secreted protein
BKN48_RS01090	COG0019	diaminopimelate decarboxylase activity
BKN48_RS01095	COG0697	spore germination
BKN48_RS01110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKN48_RS01130	COG1191	sigma factor activity
BKN48_RS01135	COG2172	sigma factor antagonist activity
BKN48_RS01140	COG1366	Belongs to the anti-sigma-factor antagonist family
BKN48_RS01145	COG1686	Belongs to the peptidase S11 family
BKN48_RS01150	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BKN48_RS01155	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BKN48_RS01160	COG4974	Belongs to the 'phage' integrase family
BKN48_RS01170	COG0735	belongs to the Fur family
BKN48_RS01175	COG1300	Membrane
BKN48_RS01185	COG0281	malic enzyme
BKN48_RS01190	COG1757	Na H antiporter
BKN48_RS01195	COG1027	Aspartate ammonia-lyase
BKN48_RS01200	COG0252	asparaginase activity
BKN48_RS01205	COG1396	sequence-specific DNA binding
BKN48_RS01210	COG1379	DNA repair
BKN48_RS01215	COG0494	nUDIX hydrolase
BKN48_RS01225	COG0667	Aldo Keto reductase
BKN48_RS01235	COG1073	alpha beta
BKN48_RS01245	COG4918	Iron-sulphur cluster biosynthesis
BKN48_RS01250	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BKN48_RS01250	COG0456	acetyltransferase
BKN48_RS01255	COG2329	Antibiotic biosynthesis monooxygenase
BKN48_RS01260	COG0456	acetyltransferase
BKN48_RS01270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKN48_RS01280	COG2211	Major facilitator Superfamily
BKN48_RS01290	COG0346	lactoylglutathione lyase activity
BKN48_RS01295	COG1072	(Pantothenic acid kinase))
BKN48_RS01300	COG3048	D-serine ammonia-lyase activity
BKN48_RS01305	COG0300	oxidoreductase activity
BKN48_RS01310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN48_RS01315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BKN48_RS01320	COG4187	Peptidase family M20/M25/M40
BKN48_RS01325	COG1902	pentaerythritol trinitrate reductase activity
BKN48_RS01330	COG0596	Alpha beta hydrolase
BKN48_RS01340	COG1234	tRNA 3'-trailer cleavage
BKN48_RS01345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BKN48_RS01350	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BKN48_RS01355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKN48_RS01365	COG0706	membrane insertase activity
BKN48_RS01370	COG3361	conserved protein (COG2071)
BKN48_RS01375	COG2195	Cleaves the N-terminal amino acid of tripeptides
BKN48_RS01380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKN48_RS01385	COG0346	lactoylglutathione lyase activity
BKN48_RS01395	COG1376	ErfK ybiS ycfS ynhG family protein
BKN48_RS01400	COG4129	membrane
BKN48_RS01405	COG1126	abc transporter atp-binding protein
BKN48_RS01410	COG0765	amino acid transport
BKN48_RS01415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKN48_RS01425	COG1597	lipid kinase activity
BKN48_RS01430	COG2814	Major facilitator Superfamily
BKN48_RS01435	COG0789	Transcriptional regulator
BKN48_RS01435	COG4978	Transcriptional regulator
BKN48_RS01440	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKN48_RS01445	COG0022	dehydrogenase e1 component
BKN48_RS01450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKN48_RS01455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKN48_RS01460	COG3426	butyrate kinase activity
BKN48_RS01465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKN48_RS01470	COG0280	phosphate acetyltransferase
BKN48_RS01475	COG3829	transcription factor binding
BKN48_RS01475	COG3290	protein histidine kinase activity
BKN48_RS01485	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BKN48_RS01490	COG2079	MmgE PrpD family protein
BKN48_RS01495	COG0372	Belongs to the citrate synthase family
BKN48_RS01500	COG1960	acyl-CoA dehydrogenase activity
BKN48_RS01505	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKN48_RS01510	COG0183	Belongs to the thiolase family
BKN48_RS01515	COG0584	glycerophosphoryl diester phosphodiesterase
BKN48_RS01520	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKN48_RS01535	COG1902	pentaerythritol trinitrate reductase activity
BKN48_RS01545	COG0745	RESPONSE REGULATOR receiver
BKN48_RS01555	COG0750	zinc metalloprotease
BKN48_RS01560	COG0497	DNA recombination
BKN48_RS01565	COG1438	arginine binding
BKN48_RS01570	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BKN48_RS01575	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BKN48_RS01580	COG0142	geranyltranstransferase activity
BKN48_RS01585	COG1722	exodeoxyribonuclease VII activity
BKN48_RS01590	COG1570	exodeoxyribonuclease VII activity
BKN48_RS01595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BKN48_RS01600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKN48_RS01605	COG1302	Protein conserved in bacteria
BKN48_RS01610	COG0439	Biotin carboxylase
BKN48_RS01615	COG0511	ligase activity, forming carbon-carbon bonds
BKN48_RS01655	COG3854	ATPases associated with a variety of cellular activities
BKN48_RS01665	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BKN48_RS01670	COG0006	proline dipeptidase activity
BKN48_RS01675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BKN48_RS01685	COG3872	metal-dependent enzyme
BKN48_RS01695	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKN48_RS01700	COG1321	iron dependent repressor
BKN48_RS01705	COG0095	Lipoate-protein ligase
BKN48_RS01710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKN48_RS01715	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKN48_RS01720	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKN48_RS01725	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BKN48_RS01730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKN48_RS01745	COG1396	sequence-specific DNA binding
BKN48_RS01755	COG0681	Belongs to the peptidase S26 family
BKN48_RS01780	COG4940	Competence protein ComGF
BKN48_RS01790	COG4970	Tfp pilus assembly protein FimT
BKN48_RS01795	COG4537	Required for transformation and DNA binding
BKN48_RS01800	COG1459	type II secretion system
BKN48_RS01805	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BKN48_RS01815	COG0598	Magnesium transport protein CorA
BKN48_RS01820	COG1253	flavin adenine dinucleotide binding
BKN48_RS01825	COG1366	Belongs to the anti-sigma-factor antagonist family
BKN48_RS01835	COG1393	Belongs to the ArsC family
BKN48_RS01845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN48_RS01855	COG0011	TIGRFAM Protein of
BKN48_RS01865	COG2866	Carboxypeptidase
BKN48_RS01870	COG1368	sulfuric ester hydrolase activity
BKN48_RS01875	COG1940	carbohydrate kinase activity
BKN48_RS01880	COG4483	Protein conserved in bacteria
BKN48_RS01885	COG0705	Rhomboid family
BKN48_RS01885	COG0457	Tetratricopeptide repeat
BKN48_RS01895	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BKN48_RS01905	COG0438	transferase activity, transferring glycosyl groups
BKN48_RS01920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BKN48_RS01925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKN48_RS01930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKN48_RS01935	COG0581	inorganic phosphate transmembrane transporter activity
BKN48_RS01940	COG0573	inorganic phosphate transmembrane transporter activity
BKN48_RS01945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BKN48_RS01950	COG0768	penicillin binding
BKN48_RS01955	COG0477	Major facilitator Superfamily
BKN48_RS01960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BKN48_RS01965	COG2839	Protein conserved in bacteria
BKN48_RS01970	COG5521	maltodextrose utilization protein MalA
BKN48_RS01975	COG1388	LysM domain
BKN48_RS01980	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BKN48_RS01985	COG4709	membrane
BKN48_RS01990	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BKN48_RS01995	COG0735	belongs to the Fur family
BKN48_RS02000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKN48_RS02010	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BKN48_RS02015	COG0513	Belongs to the DEAD box helicase family
BKN48_RS02025	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BKN48_RS02030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BKN48_RS02035	COG2384	SAM-dependent methyltransferase
BKN48_RS02040	COG2010	Cytochrome c
BKN48_RS02045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKN48_RS02050	COG0358	DNA primase activity
BKN48_RS02055	COG1671	Belongs to the UPF0178 family
BKN48_RS02060	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BKN48_RS02065	COG0517	IMP dehydrogenase activity
BKN48_RS02070	COG0751	glycine-tRNA ligase activity
BKN48_RS02075	COG0752	glycyl-tRNA synthetase alpha subunit
BKN48_RS02080	COG1381	Involved in DNA repair and RecF pathway recombination
BKN48_RS02090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BKN48_RS02095	COG0295	cytidine deaminase activity
BKN48_RS02100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BKN48_RS02105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BKN48_RS02110	COG1480	7TM receptor with intracellular HD hydrolase
BKN48_RS02120	COG1702	phosphate starvation-inducible protein PhoH
BKN48_RS02125	COG0561	phosphatase activity
BKN48_RS02140	COG4864	UPF0365 protein
BKN48_RS02145	COG1030	water channel activity
BKN48_RS02150	COG1610	YqeY-like protein
BKN48_RS02160	COG1283	sodium-dependent phosphate transmembrane transporter activity
BKN48_RS02165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKN48_RS02170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BKN48_RS02175	COG2264	protein methyltransferase activity
BKN48_RS02180	COG0484	heat shock protein binding
BKN48_RS02185	COG0443	Heat shock 70 kDa protein
BKN48_RS02190	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BKN48_RS02195	COG1420	regulation of RNA biosynthetic process
BKN48_RS02200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKN48_RS02205	COG0481	GTPase activity
BKN48_RS02215	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKN48_RS02220	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BKN48_RS02225	COG0268	Binds directly to 16S ribosomal RNA
BKN48_RS02230	COG1466	dna polymerase III delta subunit
BKN48_RS02240	COG0658	competence protein
BKN48_RS02240	COG2333	competence protein COMEC
BKN48_RS02245	COG2131	deaminase
BKN48_RS02250	COG1596	polysaccharide export
BKN48_RS02250	COG1555	photosystem II stabilization
BKN48_RS02255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BKN48_RS02260	COG2226	methyltransferase
BKN48_RS02265	COG0799	negative regulation of ribosome biogenesis
BKN48_RS02270	COG1713	HD superfamily hydrolase involved in NAD metabolism
BKN48_RS02275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BKN48_RS02280	COG1534	Rna-binding protein
BKN48_RS02285	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKN48_RS02290	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BKN48_RS02295	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BKN48_RS02310	COG2755	lipolytic protein G-D-S-L family
BKN48_RS02315	COG5632	N-Acetylmuramoyl-L-alanine amidase
BKN48_RS02315	COG3409	Peptidoglycan-binding domain 1 protein
BKN48_RS02320	COG0398	Pfam SNARE associated Golgi protein
BKN48_RS02325	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BKN48_RS02335	COG3209	COG3209 Rhs family protein
BKN48_RS02355	COG3223	Belongs to the PsiE family
BKN48_RS02360	COG0642	Histidine kinase
BKN48_RS02360	COG5002	protein histidine kinase activity
BKN48_RS02365	COG0745	RESPONSE REGULATOR receiver
BKN48_RS02370	COG2311	Membrane
BKN48_RS02380	COG0454	-acetyltransferase
BKN48_RS02385	COG2249	NAD(P)H dehydrogenase (quinone) activity
BKN48_RS02395	COG0730	response to heat
BKN48_RS02400	COG0425	Belongs to the sulfur carrier protein TusA family
BKN48_RS02405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN48_RS02405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKN48_RS02415	COG0425	Belongs to the sulfur carrier protein TusA family
BKN48_RS02415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKN48_RS02420	COG2210	Belongs to the sulfur carrier protein TusA family
BKN48_RS02425	COG1937	Protein conserved in bacteria
BKN48_RS02430	COG0662	Cupin 2, conserved barrel domain protein
BKN48_RS02445	COG0789	Transcriptional regulator
BKN48_RS02445	COG4978	Transcriptional regulator
BKN48_RS02450	COG2814	Major facilitator Superfamily
BKN48_RS02455	COG0456	acetyltransferase
BKN48_RS02460	COG1253	flavin adenine dinucleotide binding
BKN48_RS02470	COG0697	spore germination
BKN48_RS02475	COG0583	DNA-binding transcription factor activity
BKN48_RS02480	COG2072	flavoprotein involved in K transport
BKN48_RS02485	COG1230	cation diffusion facilitator family transporter
BKN48_RS02490	COG1942	4-Oxalocrotonate Tautomerase
BKN48_RS02495	COG1114	Component of the transport system for branched-chain amino acids
BKN48_RS02500	COG1687	branched-chain amino acid
BKN48_RS02505	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BKN48_RS02510	COG1522	sequence-specific DNA binding
BKN48_RS02515	COG2732	(Barnase) inhibitor
BKN48_RS02535	COG1335	isochorismatase
BKN48_RS02545	COG2318	DinB family
BKN48_RS02555	COG2070	2-Nitropropane dioxygenase
BKN48_RS02560	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BKN48_RS02570	COG2186	Transcriptional regulator
BKN48_RS02580	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS02585	COG3958	Transketolase
BKN48_RS02590	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BKN48_RS02595	COG0477	Major facilitator Superfamily
BKN48_RS02600	COG1846	Transcriptional regulator
BKN48_RS02605	COG3443	Belongs to the bacterial solute-binding protein 9 family
BKN48_RS02610	COG1595	DNA-templated transcription, initiation
BKN48_RS02615	COG0667	Aldo Keto reductase
BKN48_RS02620	COG2851	Citrate transporter
BKN48_RS02625	COG0583	DNA-binding transcription factor activity
BKN48_RS02630	COG2828	Protein conserved in bacteria
BKN48_RS02635	COG3409	Peptidoglycan-binding domain 1 protein
BKN48_RS02640	COG5566	PFAM Mor transcription activator
BKN48_RS02645	COG0596	Alpha beta hydrolase
BKN48_RS02650	COG4991	sh3 domain protein
BKN48_RS02655	COG4991	sh3 domain protein
BKN48_RS02660	COG0346	lactoylglutathione lyase activity
BKN48_RS02670	COG5577	PFAM Coat F domain
BKN48_RS02675	COG1063	alcohol dehydrogenase
BKN48_RS02685	COG5577	PFAM Coat F domain
BKN48_RS02690	COG0789	Transcriptional regulator
BKN48_RS02700	COG1064	alcohol dehydrogenase
BKN48_RS02705	COG0693	protein deglycase activity
BKN48_RS02710	COG1621	beta-fructofuranosidase activity
BKN48_RS02715	COG3716	PTS system mannose fructose sorbose family IID component
BKN48_RS02720	COG3715	PTS system
BKN48_RS02725	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKN48_RS02730	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKN48_RS02735	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BKN48_RS02735	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BKN48_RS02740	COG1113	amino acid transport
BKN48_RS02745	COG1280	lysine exporter protein (LysE YggA)
BKN48_RS02750	COG1378	Sugar-specific transcriptional regulator TrmB
BKN48_RS02755	COG1595	DNA-templated transcription, initiation
BKN48_RS02765	COG2755	lipolytic protein G-D-S-L family
BKN48_RS02765	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BKN48_RS02775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BKN48_RS02775	COG2124	cytochrome p450
BKN48_RS02780	COG1309	transcriptional regulator
BKN48_RS02785	COG2226	methyltransferase
BKN48_RS02800	COG2116	formate transmembrane transporter activity
BKN48_RS02805	COG5609	conserved protein (DUF2294)
BKN48_RS02810	COG3383	formate dehydrogenase (NAD+) activity
BKN48_RS02815	COG2427	Protein of unknown function (DUF1641)
BKN48_RS02825	COG0626	cystathionine gamma-synthase activity
BKN48_RS02830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKN48_RS02835	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BKN48_RS02840	COG2226	methyltransferase
BKN48_RS02855	COG0768	penicillin binding
BKN48_RS02860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKN48_RS02865	COG0572	uridine kinase
BKN48_RS02870	COG0826	peptidase U32
BKN48_RS02875	COG0826	peptidase U32
BKN48_RS02880	COG4122	O-methyltransferase activity
BKN48_RS02885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BKN48_RS02890	COG3906	Belongs to the UPF0473 family
BKN48_RS02895	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BKN48_RS02900	COG4472	Bacterial protein of unknown function (DUF965)
BKN48_RS02905	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKN48_RS02910	COG0628	permease
BKN48_RS02915	COG1126	abc transporter atp-binding protein
BKN48_RS02920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKN48_RS02925	COG0765	amino acid transport
BKN48_RS02930	COG0765	amino acid transport
BKN48_RS02945	COG3881	PFAM PRC-barrel domain
BKN48_RS02950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BKN48_RS02955	COG0457	Tetratricopeptide repeat
BKN48_RS02960	COG0482	sulfurtransferase activity
BKN48_RS02965	COG1104	cysteine desulfurase activity
BKN48_RS02970	COG1959	2 iron, 2 sulfur cluster binding
BKN48_RS02975	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BKN48_RS02980	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BKN48_RS02990	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BKN48_RS02995	COG0124	histidyl-tRNA synthetase
BKN48_RS03005	COG3103	Sh3 type 3 domain protein
BKN48_RS03005	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKN48_RS03005	COG4991	sh3 domain protein
BKN48_RS03010	COG1490	D-aminoacyl-tRNA deacylase activity
BKN48_RS03015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKN48_RS03020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKN48_RS03025	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BKN48_RS03025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BKN48_RS03030	COG5416	Lipopolysaccharide assembly protein A domain
BKN48_RS03035	COG0490	domain, Protein
BKN48_RS03040	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKN48_RS03040	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKN48_RS03050	COG2244	polysaccharide biosynthetic process
BKN48_RS03055	COG2323	membrane
BKN48_RS03065	COG1862	Preprotein translocase
BKN48_RS03070	COG0343	queuine tRNA-ribosyltransferase activity
BKN48_RS03075	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BKN48_RS03085	COG2255	four-way junction helicase activity
BKN48_RS03090	COG0632	four-way junction helicase activity
BKN48_RS03100	COG2814	Major facilitator Superfamily
BKN48_RS03105	COG0673	inositol 2-dehydrogenase activity
BKN48_RS03110	COG2112	serine threonine protein kinase
BKN48_RS03130	COG1115	amino acid carrier protein
BKN48_RS03135	COG0217	transcriptional regulatory protein
BKN48_RS03145	COG1388	LysM domain
BKN48_RS03150	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BKN48_RS03155	COG0157	Belongs to the NadC ModD family
BKN48_RS03160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BKN48_RS03165	COG1104	cysteine desulfurase activity
BKN48_RS03170	COG1827	regulation of RNA biosynthetic process
BKN48_RS03175	COG0077	Prephenate dehydratase
BKN48_RS03180	COG4492	Belongs to the UPF0735 family
BKN48_RS03185	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BKN48_RS03190	COG3290	protein histidine kinase activity
BKN48_RS03200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BKN48_RS03205	COG2868	ribosomal protein
BKN48_RS03210	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BKN48_RS03215	COG1994	Peptidase M50
BKN48_RS03220	COG0739	heme binding
BKN48_RS03225	COG2894	cell division
BKN48_RS03230	COG0850	regulation of cytokinetic process
BKN48_RS03235	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BKN48_RS03245	COG1077	Cell shape determining protein MreB Mrl
BKN48_RS03250	COG2003	Belongs to the UPF0758 family
BKN48_RS03255	COG0424	maF-like protein
BKN48_RS03265	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BKN48_RS03270	COG0285	dihydrofolate synthase activity
BKN48_RS03275	COG0525	valine-tRNA ligase activity
BKN48_RS03285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKN48_RS03290	COG1388	LysM domain
BKN48_RS03295	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKN48_RS03300	COG0113	porphobilinogen synthase activity
BKN48_RS03305	COG1587	Uroporphyrinogen-III synthase
BKN48_RS03310	COG0181	hydroxymethylbilane synthase activity
BKN48_RS03315	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKN48_RS03320	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BKN48_RS03330	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BKN48_RS03335	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BKN48_RS03340	COG1067	ATP-dependent peptidase activity
BKN48_RS03340	COG0470	DNA polymerase III
BKN48_RS03345	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKN48_RS03350	COG0544	peptidyl-prolyl cis-trans isomerase activity
BKN48_RS03355	COG0457	Tetratricopeptide repeat
BKN48_RS03355	COG1477	protein flavinylation
BKN48_RS03360	COG0066	3-isopropylmalate dehydratase activity
BKN48_RS03365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKN48_RS03370	COG0473	3-isopropylmalate dehydrogenase activity
BKN48_RS03375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKN48_RS03380	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BKN48_RS03385	COG0440	acetolactate synthase activity
BKN48_RS03390	COG0028	Belongs to the TPP enzyme family
BKN48_RS03400	COG0454	-acetyltransferase
BKN48_RS03410	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BKN48_RS03420	COG0622	Phosphoesterase
BKN48_RS03425	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BKN48_RS03430	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BKN48_RS03435	COG5401	PFAM Sporulation and spore germination
BKN48_RS03440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BKN48_RS03445	COG1846	Transcriptional regulator
BKN48_RS03450	COG2197	response regulator
BKN48_RS03455	COG0824	Thioesterase
BKN48_RS03460	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BKN48_RS03465	COG1053	succinate dehydrogenase
BKN48_RS03470	COG2009	succinate dehydrogenase
BKN48_RS03480	COG1719	4-vinyl reductase, 4VR
BKN48_RS03485	COG0527	aspartate kinase activity
BKN48_RS03490	COG0322	excinuclease ABC activity
BKN48_RS03495	COG3118	belongs to the thioredoxin family
BKN48_RS03500	COG3534	alpha-L-arabinofuranosidase
BKN48_RS03505	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BKN48_RS03510	COG2086	electron transfer activity
BKN48_RS03515	COG1024	Enoyl-CoA hydratase
BKN48_RS03520	COG1309	transcriptional regulator
BKN48_RS03525	COG0318	PFAM AMP-dependent synthetase and ligase
BKN48_RS03530	COG3766	membrane
BKN48_RS03535	COG1193	negative regulation of DNA recombination
BKN48_RS03540	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BKN48_RS03540	COG1796	DNA polymerase
BKN48_RS03545	COG1286	toxin biosynthetic process
BKN48_RS03550	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BKN48_RS03555	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKN48_RS03560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKN48_RS03560	COG0072	phenylalanine-tRNA ligase activity
BKN48_RS03565	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BKN48_RS03575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKN48_RS03585	COG3835	regulator
BKN48_RS03590	COG0277	FAD linked oxidase domain protein
BKN48_RS03595	COG0247	lactate metabolic process
BKN48_RS03600	COG0346	lactoylglutathione lyase activity
BKN48_RS03605	COG1966	Carbon starvation protein
BKN48_RS03610	COG3534	alpha-L-arabinofuranosidase
BKN48_RS03615	COG0395	ABC-type sugar transport system, permease component
BKN48_RS03620	COG1175	transmembrane transport
BKN48_RS03625	COG1653	transport
BKN48_RS03630	COG0371	Dehydrogenase
BKN48_RS03635	COG0647	UMP catabolic process
BKN48_RS03640	COG0235	Class ii aldolase
BKN48_RS03645	COG1069	ribulokinase activity
BKN48_RS03650	COG2160	L-arabinose isomerase activity
BKN48_RS03655	COG3507	Belongs to the glycosyl hydrolase 43 family
BKN48_RS03660	COG1363	Peptidase, m42
BKN48_RS03670	COG3326	Membrane
BKN48_RS03675	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BKN48_RS03680	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BKN48_RS03685	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BKN48_RS03695	COG1346	cytolysis
BKN48_RS03700	COG1380	Effector of murein hydrolase LrgA
BKN48_RS03705	COG3279	Response regulator of the LytR AlgR family
BKN48_RS03710	COG3275	phosphorelay sensor kinase activity
BKN48_RS03715	COG1011	Hydrolase
BKN48_RS03720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKN48_RS03730	COG0398	Pfam SNARE associated Golgi protein
BKN48_RS03735	COG1484	DNA-dependent DNA replication
BKN48_RS03740	COG3611	Membrane attachment protein
BKN48_RS03745	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKN48_RS03750	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BKN48_RS03755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKN48_RS03760	COG1733	regulation of RNA biosynthetic process
BKN48_RS03765	COG2814	Major facilitator Superfamily
BKN48_RS03770	COG0656	L-ascorbic acid biosynthetic process
BKN48_RS03775	COG0237	dephospho-CoA kinase activity
BKN48_RS03790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKN48_RS03795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKN48_RS03795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKN48_RS03800	COG5002	protein histidine kinase activity
BKN48_RS03805	COG0745	RESPONSE REGULATOR receiver
BKN48_RS03810	COG0039	L-malate dehydrogenase activity
BKN48_RS03815	COG0538	isocitrate dehydrogenase activity
BKN48_RS03820	COG0372	Belongs to the citrate synthase family
BKN48_RS03825	COG2707	UPF0756 membrane protein
BKN48_RS03830	COG0628	permease
BKN48_RS03835	COG3030	protein affecting phage T7 exclusion by the F plasmid
BKN48_RS03840	COG0469	pyruvate kinase activity
BKN48_RS03845	COG0205	6-phosphofructokinase activity
BKN48_RS03850	COG0825	malonyl-CoA metabolic process
BKN48_RS03855	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BKN48_RS03860	COG0281	malic enzyme
BKN48_RS03865	COG0587	DNA-directed DNA polymerase activity
BKN48_RS03885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BKN48_RS03895	COG4109	DRTGG domain
BKN48_RS03900	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BKN48_RS03905	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS03915	COG0165	Argininosuccinate lyase
BKN48_RS03920	COG0137	argininosuccinate synthase activity
BKN48_RS03925	COG0521	Mo-molybdopterin cofactor biosynthetic process
BKN48_RS03930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BKN48_RS03935	COG0827	DNA restriction-modification system
BKN48_RS03940	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BKN48_RS03945	COG3874	Sporulation protein YtfJ
BKN48_RS03955	COG1714	RDD family
BKN48_RS03960	COG0616	signal peptide processing
BKN48_RS03965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKN48_RS03970	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BKN48_RS03975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKN48_RS03985	COG0301	tRNA thio-modification
BKN48_RS03990	COG1104	cysteine desulfurase activity
BKN48_RS03995	COG1114	Component of the transport system for branched-chain amino acids
BKN48_RS04000	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BKN48_RS04005	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BKN48_RS04010	COG1309	transcriptional regulator
BKN48_RS04015	COG1956	GAF domain-containing protein
BKN48_RS04020	COG2199	diguanylate cyclase activity
BKN48_RS04020	COG2203	Gaf domain
BKN48_RS04025	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BKN48_RS04035	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BKN48_RS04040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKN48_RS04045	COG0454	-acetyltransferase
BKN48_RS04050	COG0517	IMP dehydrogenase activity
BKN48_RS04055	COG0123	including yeast histone deacetylase and acetoin utilization protein
BKN48_RS04060	COG1360	Flagellar Motor Protein
BKN48_RS04065	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BKN48_RS04070	COG1609	Transcriptional regulator
BKN48_RS04075	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BKN48_RS04075	COG1605	Chorismate mutase
BKN48_RS04080	COG3118	belongs to the thioredoxin family
BKN48_RS04085	COG4980	gas vesicle protein
BKN48_RS04090	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BKN48_RS04095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKN48_RS04100	COG1674	ftsk spoiiie
BKN48_RS04105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKN48_RS04110	COG4848	Belongs to the UPF0354 family
BKN48_RS04115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKN48_RS04125	COG1363	Peptidase, m42
BKN48_RS04130	COG5584	Small secreted protein
BKN48_RS04135	COG0281	malic enzyme
BKN48_RS04140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN48_RS04145	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BKN48_RS04155	COG0510	thiamine kinase activity
BKN48_RS04160	COG1523	belongs to the glycosyl hydrolase 13 family
BKN48_RS04165	COG1597	lipid kinase activity
BKN48_RS04175	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BKN48_RS04180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKN48_RS04185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKN48_RS04190	COG2252	PERMEase
BKN48_RS04195	COG4473	ABC transporter
BKN48_RS04200	COG1131	(ABC) transporter
BKN48_RS04205	COG1349	DNA-binding transcription factor activity
BKN48_RS04210	COG1187	pseudouridine synthase activity
BKN48_RS04215	COG2244	polysaccharide biosynthetic process
BKN48_RS04220	COG2081	HI0933 family
BKN48_RS04225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BKN48_RS04235	COG5578	integral membrane protein
BKN48_RS04240	COG0673	inositol 2-dehydrogenase activity
BKN48_RS04245	COG1653	transport
BKN48_RS04250	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BKN48_RS04255	COG4209	transmembrane transport
BKN48_RS04260	COG2207	Transcriptional regulator
BKN48_RS04265	COG1653	transport
BKN48_RS04270	COG0395	ABC-type sugar transport system, permease component
BKN48_RS04275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKN48_RS04280	COG2124	cytochrome p450
BKN48_RS04285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BKN48_RS04295	COG0156	8-amino-7-oxononanoate synthase activity
BKN48_RS04300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKN48_RS04310	COG1073	alpha beta
BKN48_RS04315	COG1609	Transcriptional regulator
BKN48_RS04320	COG1653	transport
BKN48_RS04325	COG1175	transmembrane transport
BKN48_RS04330	COG0395	ABC-type sugar transport system, permease component
BKN48_RS04335	COG1486	melibiose metabolic process
BKN48_RS04340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKN48_RS04345	COG0495	leucyl-tRNA aminoacylation
BKN48_RS04355	COG1366	Belongs to the anti-sigma-factor antagonist family
BKN48_RS04355	COG2202	Pas domain
BKN48_RS04360	COG2814	Major facilitator Superfamily
BKN48_RS04365	COG2433	Pfam Transposase IS66
BKN48_RS04370	COG0577	efflux transmembrane transporter activity
BKN48_RS04375	COG1136	(ABC) transporter
BKN48_RS04380	COG2205	protein histidine kinase activity
BKN48_RS04385	COG0745	RESPONSE REGULATOR receiver
BKN48_RS04390	COG0577	efflux transmembrane transporter activity
BKN48_RS04395	COG1136	(ABC) transporter
BKN48_RS04410	COG1131	(ABC) transporter
BKN48_RS04415	COG1725	Transcriptional regulator
BKN48_RS04430	COG1242	4 iron, 4 sulfur cluster binding
BKN48_RS04435	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BKN48_RS04445	COG2267	carboxylic ester hydrolase activity
BKN48_RS04450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BKN48_RS04455	COG1113	amino acid transport
BKN48_RS04460	COG0367	asparagine synthase
BKN48_RS04465	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BKN48_RS04470	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BKN48_RS04480	COG1506	peptidase
BKN48_RS04485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKN48_RS04490	COG1116	anion transmembrane transporter activity
BKN48_RS04495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKN48_RS04500	COG0494	nUDIX hydrolase
BKN48_RS04505	COG4824	toxin secretion phage lysis holin
BKN48_RS04510	COG0783	Belongs to the Dps family
BKN48_RS04525	COG1854	S-ribosylhomocysteine lyase activity
BKN48_RS04530	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BKN48_RS04535	COG0288	reversible hydration of carbon dioxide
BKN48_RS04540	COG0254	rRNA binding
BKN48_RS04545	COG1271	oxidase subunit
BKN48_RS04550	COG1294	oxidase, subunit
BKN48_RS04560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKN48_RS04565	COG1321	iron dependent repressor
BKN48_RS04565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKN48_RS04570	COG1121	(ABC) transporter
BKN48_RS04575	COG0803	Belongs to the bacterial solute-binding protein 9 family
BKN48_RS04580	COG4948	Mandelate Racemase Muconate Lactonizing
BKN48_RS04585	COG0318	PFAM AMP-dependent synthetase and ligase
BKN48_RS04590	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BKN48_RS04595	COG0596	Alpha beta hydrolase
BKN48_RS04600	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BKN48_RS04605	COG1169	isochorismate synthase
BKN48_RS04610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BKN48_RS04615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKN48_RS04620	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKN48_RS04625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKN48_RS04630	COG0438	transferase activity, transferring glycosyl groups
BKN48_RS04640	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKN48_RS04645	COG0438	transferase activity, transferring glycosyl groups
BKN48_RS04650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKN48_RS04655	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BKN48_RS04660	COG0058	SHG alpha-glucan phosphorylase activity
BKN48_RS04665	COG0297	glycogen (starch) synthase activity
BKN48_RS04670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BKN48_RS04675	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BKN48_RS04680	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BKN48_RS04810	COG3859	Proton-coupled thiamine transporter YuaJ
BKN48_RS04815	COG1247	-acetyltransferase
BKN48_RS04820	COG2268	Band 7 protein
BKN48_RS04825	COG1585	Membrane protein implicated in regulation of membrane protease activity
BKN48_RS04830	COG2318	DinB family
BKN48_RS04840	COG1454	alcohol dehydrogenase
BKN48_RS04845	COG1012	belongs to the aldehyde dehydrogenase family
BKN48_RS04850	COG1510	regulation of RNA biosynthetic process
BKN48_RS04860	COG0569	domain protein
BKN48_RS04865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BKN48_RS04870	COG4682	membrane
BKN48_RS04875	COG1705	Flagellar rod assembly protein muramidase FlgJ
BKN48_RS04880	COG0477	Major facilitator Superfamily
BKN48_RS04885	COG5553	Cysteine dioxygenase type I
BKN48_RS04895	COG1968	undecaprenyl-diphosphatase activity
BKN48_RS04900	COG0628	permease
BKN48_RS04905	COG0673	inositol 2-dehydrogenase activity
BKN48_RS04910	COG4806	L-rhamnose isomerase
BKN48_RS04915	COG3254	rhamnose metabolic process
BKN48_RS04920	COG1070	Carbohydrate kinase
BKN48_RS04925	COG1349	DNA-binding transcription factor activity
BKN48_RS04930	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS04930	COG3347	Dehydrogenase
BKN48_RS04935	COG0840	transmembrane signaling receptor activity
BKN48_RS04940	COG0840	transmembrane signaling receptor activity
BKN48_RS04945	COG0840	transmembrane signaling receptor activity
BKN48_RS04950	COG0840	transmembrane signaling receptor activity
BKN48_RS04965	COG0432	Pfam Uncharacterised protein family UPF0047
BKN48_RS04970	COG0366	Alpha amylase catalytic
BKN48_RS04975	COG1253	flavin adenine dinucleotide binding
BKN48_RS04980	COG2738	Putative neutral zinc metallopeptidase
BKN48_RS04995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKN48_RS05010	COG0166	Belongs to the GPI family
BKN48_RS05015	COG1979	alcohol dehydrogenase
BKN48_RS05020	COG1979	alcohol dehydrogenase
BKN48_RS05025	COG2155	Conserved Protein
BKN48_RS05030	COG1098	S1 RNA binding domain
BKN48_RS05035	COG0436	Aminotransferase
BKN48_RS05040	COG1522	sequence-specific DNA binding
BKN48_RS05045	COG2267	carboxylic ester hydrolase activity
BKN48_RS05055	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BKN48_RS05060	COG2205	protein histidine kinase activity
BKN48_RS05070	COG5018	Exonuclease
BKN48_RS05080	COG2814	Major facilitator Superfamily
BKN48_RS05085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKN48_RS05090	COG3011	Protein conserved in bacteria
BKN48_RS05100	COG3290	protein histidine kinase activity
BKN48_RS05105	COG4565	transcriptional regulatory protein
BKN48_RS05110	COG1744	ABC transporter substrate-binding protein PnrA-like
BKN48_RS05115	COG3845	ABC transporter
BKN48_RS05120	COG4603	Belongs to the binding-protein-dependent transport system permease family
BKN48_RS05125	COG1079	Belongs to the binding-protein-dependent transport system permease family
BKN48_RS05130	COG3493	citrate carrier protein
BKN48_RS05140	COG2111	Na H antiporter
BKN48_RS05140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKN48_RS05145	COG2111	Na H antiporter
BKN48_RS05150	COG1006	Multisubunit Na H antiporter MnhC subunit
BKN48_RS05155	COG0651	ATP synthesis coupled electron transport
BKN48_RS05160	COG1863	multisubunit Na H antiporter MnhE subunit
BKN48_RS05165	COG2212	antiporter activity
BKN48_RS05170	COG1320	monovalent cation:proton antiporter activity
BKN48_RS05175	COG2050	protein possibly involved in aromatic compounds catabolism
BKN48_RS05180	COG2197	response regulator
BKN48_RS05185	COG4585	Histidine kinase
BKN48_RS05195	COG0142	geranyltranstransferase activity
BKN48_RS05210	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BKN48_RS05215	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BKN48_RS05220	COG1335	isochorismatase
BKN48_RS05225	COG5506	Protein of unknown function (DUF1694)
BKN48_RS05240	COG0628	permease
BKN48_RS05255	COG1418	mRNA catabolic process
BKN48_RS05260	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS05270	COG1511	domain protein
BKN48_RS05275	COG0433	COG0433 Predicted ATPase
BKN48_RS05275	COG1674	ftsk spoiiie
BKN48_RS05280	COG4499	WXG100 protein secretion system (Wss), protein YukC
BKN48_RS05285	COG5417	Belongs to the EsaB family
BKN48_RS05290	COG4842	Belongs to the WXG100 family
BKN48_RS05295	COG2508	Transcriptional regulator
BKN48_RS05295	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BKN48_RS05300	COG0686	Belongs to the AlaDH PNT family
BKN48_RS05305	COG5634	Uncharacterized conserved protein (DUF2278)
BKN48_RS05310	COG3251	PFAM MbtH domain protein
BKN48_RS05315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN48_RS05320	COG3433	isochorismatase activity
BKN48_RS05320	COG1535	isochorismatase
BKN48_RS05325	COG1021	2,3-dihydroxybenzoate-AMP ligase
BKN48_RS05330	COG1169	isochorismate synthase
BKN48_RS05335	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS05340	COG2819	hydrolase of the alpha beta superfamily
BKN48_RS05345	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKN48_RS05350	COG1268	BioY protein
BKN48_RS05355	COG2056	Na+-H+ antiporter family
BKN48_RS05360	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BKN48_RS05365	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BKN48_RS05370	COG3584	3D domain protein
BKN48_RS05385	COG1252	NADH dehydrogenase
BKN48_RS05390	COG0492	ferredoxin-NADP+ reductase activity
BKN48_RS05400	COG0516	GMP reductase activity
BKN48_RS05405	COG2808	Putative FMN-binding domain
BKN48_RS05410	COG0456	acetyltransferase
BKN48_RS05415	COG0316	Belongs to the HesB IscA family
BKN48_RS05420	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BKN48_RS05425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BKN48_RS05430	COG4844	belongs to the
BKN48_RS05435	COG1252	NADH dehydrogenase
BKN48_RS05440	COG4837	Protein of unknown function (DUF1462)
BKN48_RS05445	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BKN48_RS05450	COG4946	Tricorn protease homolog
BKN48_RS05450	COG1506	peptidase
BKN48_RS05450	COG0823	Involved in the tonB-independent uptake of proteins
BKN48_RS05455	COG0083	homoserine kinase activity
BKN48_RS05460	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BKN48_RS05465	COG0460	homoserine dehydrogenase
BKN48_RS05470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKN48_RS05475	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BKN48_RS05480	COG0647	UMP catabolic process
BKN48_RS05485	COG2445	Protein of unknown function DUF86
BKN48_RS05490	COG4470	Protein conserved in bacteria
BKN48_RS05500	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BKN48_RS05505	COG0739	heme binding
BKN48_RS05515	COG3377	Domain of unknown function (DUF1805)
BKN48_RS05520	COG0737	Belongs to the 5'-nucleotidase family
BKN48_RS05525	COG0730	response to heat
BKN48_RS05530	COG1801	Protein of unknown function DUF72
BKN48_RS05540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKN48_RS05545	COG2508	Transcriptional regulator
BKN48_RS05550	COG2233	PERMEase
BKN48_RS05555	COG2233	PERMEase
BKN48_RS05560	COG3648	Uricase
BKN48_RS05560	COG3195	allantoin biosynthetic process
BKN48_RS05565	COG2351	hydroxyisourate hydrolase activity
BKN48_RS05575	COG2080	2 iron, 2 sulfur cluster binding
BKN48_RS05580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BKN48_RS05585	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BKN48_RS05590	COG2068	MobA-Related Protein
BKN48_RS05595	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BKN48_RS05600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BKN48_RS05605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKN48_RS05615	COG2356	endonuclease I
BKN48_RS05620	COG3842	ATPase activity
BKN48_RS05625	COG2188	Transcriptional regulator
BKN48_RS05630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKN48_RS05635	COG0395	ABC-type sugar transport system, permease component
BKN48_RS05640	COG1175	transmembrane transport
BKN48_RS05645	COG1653	transport
BKN48_RS05650	COG2222	sugar isomerase
BKN48_RS05655	COG0322	excinuclease ABC activity
BKN48_RS05660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKN48_RS05675	COG0346	lactoylglutathione lyase activity
BKN48_RS05680	COG0640	Transcriptional regulator
BKN48_RS05685	COG0719	Fe-S assembly protein
BKN48_RS05690	COG0822	iron-sulfur transferase activity
BKN48_RS05695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKN48_RS05700	COG0719	Fe-S assembly protein
BKN48_RS05705	COG0396	ATPase activity
BKN48_RS05715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKN48_RS05720	COG1464	Belongs to the NlpA lipoprotein family
BKN48_RS05725	COG2011	ABC-type metal ion transport system permease component
BKN48_RS05730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKN48_RS05740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKN48_RS05745	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BKN48_RS05755	COG0509	glycine decarboxylation via glycine cleavage system
BKN48_RS05760	COG1393	Belongs to the ArsC family
BKN48_RS05765	COG1960	acyl-CoA dehydrogenase activity
BKN48_RS05770	COG0183	Belongs to the thiolase family
BKN48_RS05775	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKN48_RS05775	COG1024	Enoyl-CoA hydratase
BKN48_RS05785	COG0506	proline dehydrogenase activity
BKN48_RS05795	COG5577	PFAM Coat F domain
BKN48_RS05800	COG1846	Transcriptional regulator
BKN48_RS05805	COG0477	Major facilitator Superfamily
BKN48_RS05810	COG1942	4-Oxalocrotonate Tautomerase
BKN48_RS05815	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS05820	COG0583	DNA-binding transcription factor activity
BKN48_RS05830	COG1120	ATPase activity
BKN48_RS05845	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS05850	COG0783	Belongs to the Dps family
BKN48_RS05855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKN48_RS05860	COG0745	RESPONSE REGULATOR receiver
BKN48_RS05865	COG2205	protein histidine kinase activity
BKN48_RS05865	COG2770	Histidine kinase
BKN48_RS05875	COG1309	transcriptional regulator
BKN48_RS05880	COG0114	fumarate hydratase activity
BKN48_RS05890	COG0697	spore germination
BKN48_RS05895	COG0814	amino acid
BKN48_RS05905	COG2197	response regulator
BKN48_RS05910	COG4585	Histidine kinase
BKN48_RS05915	COG4758	membrane
BKN48_RS05920	COG3595	metallopeptidase activity
BKN48_RS05925	COG1842	Phage shock protein A
BKN48_RS05930	COG4758	membrane
BKN48_RS05935	COG2814	Major facilitator Superfamily
BKN48_RS05940	COG2096	Adenosyltransferase
BKN48_RS05945	COG1120	ATPase activity
BKN48_RS05950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN48_RS05955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKN48_RS05960	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS05965	COG3386	PFAM SMP-30 Gluconolaconase
BKN48_RS05970	COG2205	protein histidine kinase activity
BKN48_RS05975	COG0745	RESPONSE REGULATOR receiver
BKN48_RS05985	COG1191	sigma factor activity
BKN48_RS05995	COG2140	Oxalate decarboxylase
BKN48_RS06005	COG0577	efflux transmembrane transporter activity
BKN48_RS06010	COG1136	(ABC) transporter
BKN48_RS06015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKN48_RS06020	COG1120	ATPase activity
BKN48_RS06025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN48_RS06030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN48_RS06035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKN48_RS06040	COG0531	amino acid
BKN48_RS06050	COG1988	membrane-bound metal-dependent
BKN48_RS06055	COG1368	sulfuric ester hydrolase activity
BKN48_RS06060	COG1910	domain protein
BKN48_RS06065	COG0725	ABC transporter, periplasmic molybdate-binding protein
BKN48_RS06070	COG4149	molybdate abc transporter
BKN48_RS06075	COG0656	L-ascorbic acid biosynthetic process
BKN48_RS06085	COG0025	NhaP-type Na H and K H
BKN48_RS06090	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKN48_RS06095	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BKN48_RS06100	COG3973	AAA domain
BKN48_RS06110	COG2860	membrane
BKN48_RS06115	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BKN48_RS06120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BKN48_RS06125	COG2217	Heavy metal translocating P-type atpase
BKN48_RS06130	COG2217	Heavy metal translocating P-type atpase
BKN48_RS06135	COG2608	mercury ion transmembrane transporter activity
BKN48_RS06140	COG1937	Protein conserved in bacteria
BKN48_RS06145	COG0673	inositol 2-dehydrogenase activity
BKN48_RS06150	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKN48_RS06155	COG1289	transmembrane transporter activity
BKN48_RS06165	COG2076	Multidrug Resistance protein
BKN48_RS06170	COG1309	transcriptional regulator
BKN48_RS06175	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS06195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BKN48_RS06200	COG0557	exoribonuclease II activity
BKN48_RS06205	COG1647	Serine aminopeptidase, S33
BKN48_RS06210	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKN48_RS06215	COG0596	Alpha beta hydrolase
BKN48_RS06220	COG1476	TRANSCRIPTIONal
BKN48_RS06225	COG1396	sequence-specific DNA binding
BKN48_RS06230	COG1396	sequence-specific DNA binding
BKN48_RS06235	COG1733	regulation of RNA biosynthetic process
BKN48_RS06240	COG0840	transmembrane signaling receptor activity
BKN48_RS06245	COG1174	glycine betaine transport
BKN48_RS06250	COG1732	Glycine betaine
BKN48_RS06255	COG1174	glycine betaine transport
BKN48_RS06260	COG1125	glycine betaine transport
BKN48_RS06260	COG0517	IMP dehydrogenase activity
BKN48_RS06265	COG1510	regulation of RNA biosynthetic process
BKN48_RS06270	COG1174	glycine betaine transport
BKN48_RS06275	COG1732	Glycine betaine
BKN48_RS06280	COG1174	glycine betaine transport
BKN48_RS06285	COG0517	IMP dehydrogenase activity
BKN48_RS06285	COG1125	glycine betaine transport
BKN48_RS06290	COG1510	regulation of RNA biosynthetic process
BKN48_RS06295	COG2095	MarC family integral membrane protein
BKN48_RS06305	COG3064	Membrane
BKN48_RS06310	COG4640	response to antibiotic
BKN48_RS06315	COG0456	acetyltransferase
BKN48_RS06320	COG0148	phosphopyruvate hydratase activity
BKN48_RS06325	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BKN48_RS06330	COG0149	triose-phosphate isomerase activity
BKN48_RS06335	COG0126	phosphoglycerate kinase activity
BKN48_RS06345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKN48_RS06350	COG2390	Transcriptional regulator
BKN48_RS06355	COG2814	Major facilitator Superfamily
BKN48_RS06360	COG1609	Transcriptional regulator
BKN48_RS06365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN48_RS06370	COG0583	DNA-binding transcription factor activity
BKN48_RS06375	COG0697	spore germination
BKN48_RS06380	COG1113	amino acid transport
BKN48_RS06385	COG3858	chitin binding
BKN48_RS06390	COG1556	Lactate utilization protein
BKN48_RS06395	COG1139	Iron-sulfur cluster binding protein
BKN48_RS06400	COG0247	lactate metabolic process
BKN48_RS06405	COG2197	response regulator
BKN48_RS06410	COG4585	Histidine kinase
BKN48_RS06415	COG0842	Transport permease protein
BKN48_RS06420	COG1131	(ABC) transporter
BKN48_RS06425	COG0596	Alpha beta hydrolase
BKN48_RS06430	COG2208	phosphoserine phosphatase activity
BKN48_RS06435	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BKN48_RS06440	COG1874	Beta-galactosidase
BKN48_RS06445	COG3833	ABC-type maltose transport systems, permease component
BKN48_RS06450	COG1175	transmembrane transport
BKN48_RS06455	COG2182	Extracellular solute-binding protein
BKN48_RS06460	COG1609	Transcriptional regulator
BKN48_RS06465	COG2186	Transcriptional regulator
BKN48_RS06470	COG1620	l-lactate permease
BKN48_RS06475	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BKN48_RS06485	COG5039	Polysaccharide pyruvyl transferase
BKN48_RS06490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKN48_RS06495	COG0110	maltose O-acetyltransferase activity
BKN48_RS06500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BKN48_RS06505	COG2244	polysaccharide biosynthetic process
BKN48_RS06510	COG1216	Glycosyl transferase, family 2
BKN48_RS06515	COG5039	Polysaccharide pyruvyl transferase
BKN48_RS06520	COG1216	Glycosyl transferase, family 2
BKN48_RS06530	COG0438	transferase activity, transferring glycosyl groups
BKN48_RS06535	COG1215	transferase activity, transferring glycosyl groups
BKN48_RS06540	COG0438	transferase activity, transferring glycosyl groups
BKN48_RS06545	COG1086	Polysaccharide biosynthesis protein
BKN48_RS06550	COG0489	protein tyrosine kinase activity
BKN48_RS06555	COG3944	biosynthesis protein
BKN48_RS06560	COG1396	sequence-specific DNA binding
BKN48_RS06565	COG2272	Belongs to the type-B carboxylesterase lipase family
BKN48_RS06575	COG3479	Phenolic acid decarboxylase
BKN48_RS06585	COG1794	racemase activity, acting on amino acids and derivatives
BKN48_RS06590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKN48_RS06595	COG1621	beta-fructofuranosidase activity
BKN48_RS06600	COG1621	beta-fructofuranosidase activity
BKN48_RS06605	COG0531	amino acid
BKN48_RS06610	COG1309	transcriptional regulator
BKN48_RS06615	COG2076	Multidrug Resistance protein
BKN48_RS06620	COG2076	Multidrug Resistance protein
BKN48_RS06635	COG0740	serine-type endopeptidase activity
BKN48_RS06640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKN48_RS06645	COG0366	Alpha amylase catalytic
BKN48_RS06650	COG1554	hydrolase, family 65, central catalytic
BKN48_RS06655	COG5521	maltodextrose utilization protein MalA
BKN48_RS06660	COG3833	ABC-type maltose transport systems, permease component
BKN48_RS06665	COG1175	transmembrane transport
BKN48_RS06670	COG2182	Extracellular solute-binding protein
BKN48_RS06675	COG0366	Alpha amylase catalytic
BKN48_RS06680	COG1609	Transcriptional regulator
BKN48_RS06685	COG1611	Belongs to the LOG family
BKN48_RS06690	COG1694	Mazg nucleotide pyrophosphohydrolase
BKN48_RS06695	COG0659	secondary active sulfate transmembrane transporter activity
BKN48_RS06700	COG0288	reversible hydration of carbon dioxide
BKN48_RS06705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKN48_RS06710	COG0577	efflux transmembrane transporter activity
BKN48_RS06715	COG1136	(ABC) transporter
BKN48_RS06720	COG5002	protein histidine kinase activity
BKN48_RS06725	COG0745	RESPONSE REGULATOR receiver
BKN48_RS06735	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BKN48_RS06740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKN48_RS06745	COG1481	regulation of sporulation
BKN48_RS06750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BKN48_RS06755	COG1660	Displays ATPase and GTPase activities
BKN48_RS06760	COG1051	belongs to the nudix hydrolase family
BKN48_RS06765	COG0492	ferredoxin-NADP+ reductase activity
BKN48_RS06770	COG0791	NLP P60 protein
BKN48_RS06770	COG3883	PFAM NLP P60 protein
BKN48_RS06775	COG0457	Tetratricopeptide repeat
BKN48_RS06780	COG1132	(ABC) transporter
BKN48_RS06800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BKN48_RS06800	COG0140	phosphoribosyl-ATP diphosphatase activity
BKN48_RS06805	COG0107	imidazoleglycerol-phosphate synthase activity
BKN48_RS06810	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BKN48_RS06815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BKN48_RS06820	COG0131	Imidazoleglycerol-phosphate dehydratase
BKN48_RS06825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BKN48_RS06830	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BKN48_RS06835	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BKN48_RS06840	COG4990	cell redox homeostasis
BKN48_RS06845	COG5297	Belongs to the glycosyl hydrolase family 6
BKN48_RS06850	COG0110	maltose O-acetyltransferase activity
BKN48_RS06855	COG0546	phosphoglycolate phosphatase activity
BKN48_RS06860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BKN48_RS06865	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BKN48_RS06870	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BKN48_RS06875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BKN48_RS06880	COG0363	glucosamine-6-phosphate deaminase activity
BKN48_RS06885	COG2188	Transcriptional regulator
BKN48_RS06890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BKN48_RS06895	COG1950	PFAM Membrane protein of
BKN48_RS06900	COG1983	PspC domain protein
BKN48_RS06905	COG3595	metallopeptidase activity
BKN48_RS06920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKN48_RS06925	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKN48_RS06930	COG0556	nucleotide-excision repair
BKN48_RS06935	COG4897	Protein conserved in bacteria
BKN48_RS06940	COG3848	Pyruvate phosphate dikinase
BKN48_RS06940	COG0574	Belongs to the PEP-utilizing enzyme family
BKN48_RS06945	COG1309	transcriptional regulator
BKN48_RS06950	COG2814	Major facilitator Superfamily
BKN48_RS06955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKN48_RS06965	COG3409	Peptidoglycan-binding domain 1 protein
BKN48_RS06965	COG0793	Belongs to the peptidase S41A family
BKN48_RS06970	COG2177	Part of the ABC transporter FtsEX involved in
BKN48_RS06975	COG2884	Cell division ATP-binding protein ftsE
BKN48_RS06980	COG2010	Cytochrome c
BKN48_RS06985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKN48_RS06990	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BKN48_RS06995	COG0653	protein targeting
BKN48_RS07000	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BKN48_RS07015	COG1516	flagellar protein fliS
BKN48_RS07020	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BKN48_RS07025	COG1334	flagellar protein FlaG
BKN48_RS07030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKN48_RS07035	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BKN48_RS07040	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BKN48_RS07050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKN48_RS07055	COG4786	Flagellar basal body rod
BKN48_RS07055	COG1256	bacterial-type flagellum assembly
BKN48_RS07060	COG3418	PFAM FlgN family protein
BKN48_RS07065	COG2747	anti-sigma28 factor FlgM
BKN48_RS07075	COG1040	competence protein
BKN48_RS07085	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BKN48_RS07090	COG1307	EDD domain protein, DegV family
BKN48_RS07095	COG2197	response regulator
BKN48_RS07100	COG4585	Histidine kinase
BKN48_RS07105	COG1739	Uncharacterized protein family UPF0029
BKN48_RS07110	COG1316	TRANSCRIPTIONal
BKN48_RS07115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKN48_RS07120	COG0438	transferase activity, transferring glycosyl groups
BKN48_RS07125	COG1215	transferase activity, transferring glycosyl groups
BKN48_RS07130	COG3206	protein involved in exopolysaccharide biosynthesis
BKN48_RS07135	COG3307	-O-antigen
BKN48_RS07140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKN48_RS07145	COG0438	transferase activity, transferring glycosyl groups
BKN48_RS07145	COG0297	glycogen (starch) synthase activity
BKN48_RS07150	COG2244	polysaccharide biosynthetic process
BKN48_RS07165	COG2247	cell wall binding repeat
BKN48_RS07165	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKN48_RS07170	COG2247	cell wall binding repeat
BKN48_RS07170	COG2385	sporulation resulting in formation of a cellular spore
BKN48_RS07180	COG1316	TRANSCRIPTIONal
BKN48_RS07185	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BKN48_RS07205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKN48_RS07210	COG1134	teichoic acid transport
BKN48_RS07215	COG1682	transport, permease protein
BKN48_RS07220	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BKN48_RS07225	COG1442	glycosyl transferase family 8
BKN48_RS07225	COG1216	Glycosyl transferase, family 2
BKN48_RS07265	COG4193	domain, Protein
BKN48_RS07270	COG1482	cell wall glycoprotein biosynthetic process
BKN48_RS07280	COG0697	spore germination
BKN48_RS07285	COG0814	amino acid
BKN48_RS07295	COG2814	Major facilitator Superfamily
BKN48_RS07300	COG1316	TRANSCRIPTIONal
BKN48_RS07305	COG0561	phosphatase activity
BKN48_RS07310	COG0791	NLP P60 protein
BKN48_RS07320	COG2843	Capsule synthesis protein
BKN48_RS07330	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BKN48_RS07335	COG1609	Transcriptional regulator
BKN48_RS07340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKN48_RS07345	COG1869	D-ribose catabolic process
BKN48_RS07350	COG1129	ABC transporter
BKN48_RS07355	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKN48_RS07360	COG1879	ABC-type sugar transport system periplasmic component
BKN48_RS07365	COG3103	Sh3 type 3 domain protein
BKN48_RS07375	COG2249	NAD(P)H dehydrogenase (quinone) activity
BKN48_RS07380	COG3527	Alpha-acetolactate decarboxylase
BKN48_RS07385	COG0028	Belongs to the TPP enzyme family
BKN48_RS07390	COG0583	DNA-binding transcription factor activity
BKN48_RS07395	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BKN48_RS07410	COG5337	Spore coat protein CotH
BKN48_RS07420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKN48_RS07430	COG0405	Gamma-glutamyltransferase
BKN48_RS07435	COG1522	sequence-specific DNA binding
BKN48_RS07440	COG2059	Chromate
BKN48_RS07445	COG2059	Chromate
BKN48_RS07460	COG5444	nuclease activity
BKN48_RS07475	COG3878	Protein conserved in bacteria
BKN48_RS07480	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BKN48_RS07485	COG4464	protein tyrosine phosphatase activity
BKN48_RS07490	COG0489	protein tyrosine kinase activity
BKN48_RS07495	COG3944	biosynthesis protein
BKN48_RS07505	COG4715	Zinc finger, swim domain protein
BKN48_RS07510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKN48_RS07515	COG0561	phosphatase activity
BKN48_RS07520	COG1349	DNA-binding transcription factor activity
BKN48_RS07525	COG0629	single-stranded DNA binding
BKN48_RS07540	COG3764	Sortase (surface protein transpeptidase)
BKN48_RS07550	COG3279	Response regulator of the LytR AlgR family
BKN48_RS07555	COG0745	RESPONSE REGULATOR receiver
BKN48_RS07555	COG2972	Histidine kinase
BKN48_RS07560	COG1970	mechanosensitive ion channel activity
BKN48_RS07565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKN48_RS07570	COG0457	Tetratricopeptide repeat
BKN48_RS07575	COG4786	Flagellar basal body rod
BKN48_RS07580	COG4786	Flagellar basal body rod
BKN48_RS07585	COG1077	Cell shape determining protein MreB Mrl
BKN48_RS07590	COG1609	Transcriptional regulator
BKN48_RS07595	COG1846	Transcriptional regulator
BKN48_RS07600	COG2814	Major facilitator Superfamily
BKN48_RS07605	COG3420	alginic acid biosynthetic process
BKN48_RS07610	COG1953	Uracil, thiamine, allantoin
BKN48_RS07615	COG0477	Major facilitator Superfamily
BKN48_RS07620	COG1335	isochorismatase
BKN48_RS07630	COG0004	ammonium transporteR
BKN48_RS07635	COG0347	Belongs to the P(II) protein family
BKN48_RS07640	COG0671	phosphoesterase, PA-phosphatase related
BKN48_RS07650	COG0739	heme binding
BKN48_RS07655	COG1247	-acetyltransferase
BKN48_RS07675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKN48_RS07680	COG0789	Transcriptional regulator
BKN48_RS07690	COG2910	NAD(P)H-binding
BKN48_RS07695	COG1959	2 iron, 2 sulfur cluster binding
BKN48_RS07700	COG0804	urea catabolic process
BKN48_RS07705	COG0832	Belongs to the urease beta subunit family
BKN48_RS07710	COG0831	urea catabolic process
BKN48_RS07725	COG3237	CsbD-like
BKN48_RS07730	COG1994	Peptidase M50
BKN48_RS07735	COG0457	Tetratricopeptide repeat
BKN48_RS07740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKN48_RS07745	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BKN48_RS07755	COG2304	oxidoreductase activity
BKN48_RS07765	COG2304	oxidoreductase activity
BKN48_RS07770	COG2385	sporulation resulting in formation of a cellular spore
BKN48_RS07775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKN48_RS07785	COG4836	Membrane
BKN48_RS07795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BKN48_RS07800	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BKN48_RS07805	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BKN48_RS07810	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BKN48_RS07815	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKN48_RS07820	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BKN48_RS07835	COG0356	it plays a direct role in the translocation of protons across the membrane
BKN48_RS07845	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BKN48_RS07850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKN48_RS07855	COG4475	Protein of unknown function (DUF436)
BKN48_RS07860	COG0698	ribose 5-phosphate isomerase
BKN48_RS07865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKN48_RS07870	COG1971	Probably functions as a manganese efflux pump
BKN48_RS07875	COG0009	L-threonylcarbamoyladenylate synthase
BKN48_RS07880	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BKN48_RS07900	COG2890	protein-(glutamine-N5) methyltransferase activity
BKN48_RS07905	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BKN48_RS07910	COG0346	lactoylglutathione lyase activity
BKN48_RS07915	COG0789	Transcriptional regulator
BKN48_RS07920	COG0679	Auxin Efflux Carrier
BKN48_RS07925	COG0281	malic enzyme
BKN48_RS07930	COG1435	thymidine kinase activity
BKN48_RS07940	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BKN48_RS07950	COG1494	fructose-1,6-bisphosphatase
BKN48_RS07955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKN48_RS07960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BKN48_RS07965	COG0191	fructose-bisphosphate aldolase activity
BKN48_RS07970	COG2204	response regulator
BKN48_RS07975	COG4821	SIS domain
BKN48_RS07980	COG0504	CTP synthase activity
BKN48_RS07985	COG3343	RNA polymerase activity
BKN48_RS07990	COG1960	acyl-CoA dehydrogenase activity
BKN48_RS07995	COG0247	lactate metabolic process
BKN48_RS07995	COG2181	nitrate reductase activity
BKN48_RS08000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKN48_RS08005	COG4294	response to UV
BKN48_RS08015	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKN48_RS08020	COG1132	(ABC) transporter
BKN48_RS08025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKN48_RS08035	COG2181	nitrate reductase activity
BKN48_RS08040	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BKN48_RS08045	COG1140	nitrate reductase beta subunit
BKN48_RS08050	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BKN48_RS08055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKN48_RS08065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKN48_RS08070	COG2223	nitrite transmembrane transporter activity
BKN48_RS08075	COG0018	arginyl-trna synthetase
BKN48_RS08080	COG4506	Protein conserved in bacteria
BKN48_RS08090	COG0535	radical SAM domain protein
BKN48_RS08100	COG1131	(ABC) transporter
BKN48_RS08105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKN48_RS08110	COG0612	Peptidase, M16
BKN48_RS08115	COG0612	Peptidase, M16
BKN48_RS08125	COG3391	amine dehydrogenase activity
BKN48_RS08130	COG3391	amine dehydrogenase activity
BKN48_RS08140	COG0457	Tetratricopeptide repeat
BKN48_RS08155	COG0010	Belongs to the arginase family
BKN48_RS08160	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BKN48_RS08165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKN48_RS08180	COG1994	Peptidase M50
BKN48_RS08185	COG1942	4-Oxalocrotonate Tautomerase
BKN48_RS08190	COG1846	Transcriptional regulator
BKN48_RS08195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKN48_RS08205	COG0477	Major facilitator Superfamily
BKN48_RS08210	COG1959	2 iron, 2 sulfur cluster binding
BKN48_RS08215	COG3465	dGTPase activity
BKN48_RS08220	COG1078	dGTPase activity
BKN48_RS08225	COG4844	belongs to the
BKN48_RS08235	COG0697	spore germination
BKN48_RS08240	COG0095	Lipoate-protein ligase
BKN48_RS08245	COG0583	DNA-binding transcription factor activity
BKN48_RS08250	COG0280	phosphate acetyltransferase
BKN48_RS08255	COG3253	May function as heme-dependent peroxidase
BKN48_RS08260	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS08265	COG0436	Aminotransferase
BKN48_RS08270	COG2814	Major facilitator Superfamily
BKN48_RS08275	COG0151	Belongs to the GarS family
BKN48_RS08280	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS08285	COG1917	Cupin 2, conserved barrel domain protein
BKN48_RS08290	COG0077	Prephenate dehydratase
BKN48_RS08295	COG2814	Major facilitator Superfamily
BKN48_RS08300	COG0833	amino acid
BKN48_RS08305	COG4187	Peptidase family M20/M25/M40
BKN48_RS08310	COG1012	belongs to the aldehyde dehydrogenase family
BKN48_RS08315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKN48_RS08325	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BKN48_RS08330	COG1091	dTDP-4-dehydrorhamnose reductase activity
BKN48_RS08335	COG1088	dTDP-glucose 4,6-dehydratase activity
BKN48_RS08340	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BKN48_RS08345	COG3980	spore coat polysaccharide biosynthesis protein
BKN48_RS08350	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BKN48_RS08355	COG2089	acid synthase
BKN48_RS08360	COG0456	acetyltransferase
BKN48_RS08365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKN48_RS08370	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BKN48_RS08375	COG0463	Glycosyl transferase, family 2
BKN48_RS08390	COG2363	Small membrane protein
BKN48_RS08395	COG2233	PERMEase
BKN48_RS08405	COG1012	belongs to the aldehyde dehydrogenase family
BKN48_RS08410	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BKN48_RS08415	COG1216	Glycosyl transferase, family 2
BKN48_RS08430	COG1695	Transcriptional regulator
BKN48_RS08435	COG0351	phosphomethylpyrimidine kinase
BKN48_RS08445	COG1621	beta-fructofuranosidase activity
BKN48_RS08450	COG1263	PTS System
BKN48_RS08450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKN48_RS08455	COG2116	formate transmembrane transporter activity
BKN48_RS08460	COG3711	transcriptional antiterminator
BKN48_RS08470	COG1404	Belongs to the peptidase S8 family
BKN48_RS08475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN48_RS08480	COG0778	Nitroreductase
BKN48_RS08485	COG0772	Belongs to the SEDS family
BKN48_RS08495	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BKN48_RS08500	COG1845	cytochrome c oxidase, subunit III
BKN48_RS08505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKN48_RS08510	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKN48_RS08515	COG2261	transglycosylase associated protein
BKN48_RS08520	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BKN48_RS08525	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BKN48_RS08530	COG2246	polysaccharide biosynthetic process
BKN48_RS08535	COG1309	transcriptional regulator
BKN48_RS08545	COG3162	membrane
BKN48_RS08550	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKN48_RS08555	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BKN48_RS08560	COG2837	iron assimilation
BKN48_RS08565	COG2822	iron ion transport
BKN48_RS08570	COG0672	)-iron permease
BKN48_RS08575	COG0352	thiamine-phosphate diphosphorylase activity
BKN48_RS08580	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BKN48_RS08585	COG0583	DNA-binding transcription factor activity
BKN48_RS08590	COG1380	Effector of murein hydrolase LrgA
BKN48_RS08595	COG1346	cytolysis
BKN48_RS08600	COG2814	Major facilitator Superfamily
BKN48_RS08605	COG4895	conserved protein (DUF2196)
BKN48_RS08610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BKN48_RS08615	COG0346	lactoylglutathione lyase activity
BKN48_RS08625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKN48_RS08630	COG1404	Belongs to the peptidase S8 family
BKN48_RS08635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKN48_RS08635	COG1263	PTS System
BKN48_RS08640	COG3711	transcriptional antiterminator
BKN48_RS08645	COG1442	glycosyl transferase family 8
BKN48_RS08650	COG5522	Integral membrane protein (intg_mem_TP0381)
BKN48_RS08655	COG1846	Transcriptional regulator
BKN48_RS08660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BKN48_RS08665	COG2234	aminopeptidase activity
BKN48_RS08680	COG2814	Major facilitator Superfamily
BKN48_RS08685	COG2357	RelA SpoT domain protein
BKN48_RS08690	COG1575	Belongs to the MenA family. Type 1 subfamily
BKN48_RS08705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN48_RS08710	COG1696	Membrane protein involved in D-alanine export
BKN48_RS08715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKN48_RS08720	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BKN48_RS08725	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BKN48_RS08730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKN48_RS08735	COG1486	melibiose metabolic process
BKN48_RS08740	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKN48_RS08745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKN48_RS08750	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKN48_RS08755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKN48_RS08755	COG3711	transcriptional antiterminator
BKN48_RS08765	COG2094	Belongs to the DNA glycosylase MPG family
BKN48_RS08770	COG0753	catalase activity
BKN48_RS08775	COG2814	Major facilitator Superfamily
BKN48_RS08780	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BKN48_RS08785	COG1131	(ABC) transporter
BKN48_RS08805	COG1595	DNA-templated transcription, initiation
BKN48_RS08810	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BKN48_RS08820	COG4152	abc transporter atp-binding protein
BKN48_RS08830	COG3279	Response regulator of the LytR AlgR family
BKN48_RS08855	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BKN48_RS08860	COG4988	ABC transporter
BKN48_RS08865	COG1294	oxidase, subunit
BKN48_RS08870	COG1271	oxidase subunit
BKN48_RS08875	COG3493	citrate carrier protein
BKN48_RS08880	COG0501	Belongs to the peptidase M48B family
BKN48_RS08890	COG0726	polysaccharide deacetylase
BKN48_RS08905	COG3842	ATPase activity
BKN48_RS08910	COG2508	Transcriptional regulator
BKN48_RS08915	COG1012	belongs to the aldehyde dehydrogenase family
BKN48_RS08920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKN48_RS08930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKN48_RS08940	COG4585	Histidine kinase
BKN48_RS08945	COG2197	response regulator
BKN48_RS08950	COG2195	Cleaves the N-terminal amino acid of tripeptides
BKN48_RS08965	COG4894	glucomannan catabolic process
BKN48_RS08970	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKN48_RS08975	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKN48_RS08980	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS08985	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BKN48_RS08990	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BKN48_RS08995	COG2610	gluconate transmembrane transporter activity
BKN48_RS09005	COG0500	methyltransferase
BKN48_RS09010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BKN48_RS09025	COG0693	protein deglycase activity
BKN48_RS09025	COG0753	catalase activity
BKN48_RS09030	COG2851	Citrate transporter
BKN48_RS09035	COG2273	Hydrolase Family 16
BKN48_RS09040	COG3711	transcriptional antiterminator
BKN48_RS09050	COG2270	Major facilitator Superfamily
BKN48_RS09055	COG0513	Belongs to the DEAD box helicase family
BKN48_RS09060	COG2755	lipolytic protein G-D-S-L family
BKN48_RS09060	COG3401	FG-GAP repeat protein
BKN48_RS09115	COG0697	spore germination
BKN48_RS09120	COG0589	response to stress
BKN48_RS09125	COG2723	6-phospho-beta-galactosidase activity
BKN48_RS09130	COG1263	PTS System
BKN48_RS09130	COG2190	(PTS) system
BKN48_RS09130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKN48_RS09140	COG5444	nuclease activity
BKN48_RS09155	COG3507	Belongs to the glycosyl hydrolase 43 family
BKN48_RS09170	COG2986	histidine ammonia-lyase
BKN48_RS09175	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BKN48_RS09180	COG1228	amidohydrolase
BKN48_RS09185	COG0010	Belongs to the arginase family
BKN48_RS09190	COG0833	amino acid
BKN48_RS09195	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BKN48_RS09200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BKN48_RS09205	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BKN48_RS09210	COG2390	Transcriptional regulator
BKN48_RS09220	COG3192	ethanolamine utilization protein
BKN48_RS09225	COG2079	MmgE PrpD family protein
BKN48_RS09230	COG1473	amidohydrolase
BKN48_RS09235	COG1126	abc transporter atp-binding protein
BKN48_RS09240	COG0765	amino acid transport
BKN48_RS09245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKN48_RS09250	COG0456	acetyltransferase
BKN48_RS09255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN48_RS09260	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BKN48_RS09265	COG0561	phosphatase activity
BKN48_RS09295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKN48_RS09300	COG5294	Protein conserved in bacteria
BKN48_RS09305	COG0577	efflux transmembrane transporter activity
BKN48_RS09310	COG1136	(ABC) transporter
BKN48_RS09315	COG2205	protein histidine kinase activity
BKN48_RS09320	COG0745	RESPONSE REGULATOR receiver
BKN48_RS09325	COG0191	fructose-bisphosphate aldolase activity
BKN48_RS09330	COG1082	Xylose isomerase domain protein TIM barrel
BKN48_RS09335	COG1082	Xylose isomerase domain protein TIM barrel
BKN48_RS09340	COG0673	inositol 2-dehydrogenase activity
BKN48_RS09345	COG2814	Major facilitator Superfamily
BKN48_RS09350	COG1082	Xylose isomerase domain protein TIM barrel
BKN48_RS09355	COG3962	Belongs to the TPP enzyme family
BKN48_RS09360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKN48_RS09370	COG1012	belongs to the aldehyde dehydrogenase family
BKN48_RS09375	COG1349	DNA-binding transcription factor activity
BKN48_RS09380	COG0667	Aldo Keto reductase
BKN48_RS09410	COG2814	Major facilitator Superfamily
BKN48_RS09415	COG0326	Molecular chaperone. Has ATPase activity
BKN48_RS09425	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS09430	COG1309	transcriptional regulator
BKN48_RS09435	COG1012	belongs to the aldehyde dehydrogenase family
BKN48_RS09445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BKN48_RS09455	COG1714	RDD family
BKN48_RS09460	COG2311	Membrane
BKN48_RS09465	COG1917	Cupin 2, conserved barrel domain protein
BKN48_RS09470	COG1309	transcriptional regulator
BKN48_RS09475	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS09480	COG1846	Transcriptional regulator
BKN48_RS09485	COG1380	Effector of murein hydrolase LrgA
BKN48_RS09490	COG1346	cytolysis
BKN48_RS09495	COG5039	Polysaccharide pyruvyl transferase
BKN48_RS09500	COG1929	Belongs to the glycerate kinase type-1 family
BKN48_RS09505	COG1802	Transcriptional regulator
BKN48_RS09510	COG1070	Carbohydrate kinase
BKN48_RS09515	COG2610	gluconate transmembrane transporter activity
BKN48_RS09520	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BKN48_RS09525	COG0450	alkyl hydroperoxide reductase
BKN48_RS09530	COG3634	alkyl hydroperoxide reductase activity
BKN48_RS09540	COG2723	6-phospho-beta-galactosidase activity
BKN48_RS09550	COG2188	Transcriptional regulator
BKN48_RS09560	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BKN48_RS09605	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BKN48_RS09620	COG1063	alcohol dehydrogenase
BKN48_RS09640	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BKN48_RS09645	COG0456	acetyltransferase
BKN48_RS09650	COG0457	Tetratricopeptide repeat
BKN48_RS09660	COG0010	Belongs to the arginase family
BKN48_RS09665	COG0833	amino acid
BKN48_RS09670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKN48_RS09675	COG3829	transcription factor binding
BKN48_RS09685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKN48_RS09690	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BKN48_RS09695	COG4853	Protein conserved in bacteria
BKN48_RS09700	COG4863	YycH protein
BKN48_RS09705	COG5002	protein histidine kinase activity
BKN48_RS09710	COG0745	RESPONSE REGULATOR receiver
BKN48_RS09740	COG0346	lactoylglutathione lyase activity
BKN48_RS09745	COG0305	Participates in initiation and elongation during chromosome replication
BKN48_RS09765	COG3093	addiction module antidote protein HigA
BKN48_RS09770	COG2807	transmembrane transport
BKN48_RS09775	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKN48_RS09780	COG0359	binds to the 23S rRNA
BKN48_RS09785	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BKN48_RS09790	COG4241	membrane
BKN48_RS09800	COG5577	PFAM Coat F domain
BKN48_RS09805	COG1733	regulation of RNA biosynthetic process
BKN48_RS09810	COG1227	inorganic diphosphatase activity
BKN48_RS09825	COG2271	Major facilitator Superfamily
BKN48_RS09830	COG4978	Transcriptional regulator
BKN48_RS09830	COG0789	Transcriptional regulator
BKN48_RS09840	COG4319	ketosteroid isomerase
BKN48_RS09845	COG1357	PFAM Pentapeptide repeats (8 copies)
BKN48_RS09850	COG2814	Major facilitator Superfamily
BKN48_RS09855	COG0583	DNA-binding transcription factor activity
BKN48_RS09860	COG2153	protein acetylation
BKN48_RS09870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN48_RS09875	COG1846	Transcriptional regulator
BKN48_RS09880	COG2153	protein acetylation
BKN48_RS09885	COG2364	Membrane
BKN48_RS09905	COG0640	Transcriptional regulator
BKN48_RS09925	COG1331	Highly conserved protein containing a thioredoxin domain
BKN48_RS09930	COG1266	CAAX protease self-immunity
BKN48_RS09935	COG0477	Major facilitator Superfamily
BKN48_RS09935	COG2814	Major facilitator Superfamily
BKN48_RS09940	COG0110	maltose O-acetyltransferase activity
BKN48_RS09945	COG0346	lactoylglutathione lyase activity
BKN48_RS09950	COG1609	Transcriptional regulator
BKN48_RS09955	COG0708	Exodeoxyribonuclease III
BKN48_RS09960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BKN48_RS09965	COG0629	single-stranded DNA binding
BKN48_RS09970	COG0360	Binds together with S18 to 16S ribosomal RNA
BKN48_RS09975	COG0012	GTP binding
BKN48_RS09980	COG0243	molybdopterin cofactor binding
BKN48_RS09985	COG4481	Protein conserved in bacteria
BKN48_RS09990	COG3949	Membrane
BKN48_RS10000	COG1475	DNA binding
BKN48_RS10005	COG1192	Involved in chromosome partitioning
BKN48_RS10015	COG1475	DNA binding
BKN48_RS10020	COG0357	Ribosomal RNA small subunit methyltransferase G
BKN48_RS10025	COG0445	tRNA wobble uridine modification
BKN48_RS10030	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BKN48_RS10035	COG1847	R3H domain protein
BKN48_RS10040	COG0706	membrane insertase activity
BKN48_RS10045	COG0594	ribonuclease P activity
BKN48_RS10055	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKN48_RS10060	COG0592	DNA-directed DNA polymerase activity
BKN48_RS10065	COG2501	S4 domain
BKN48_RS10070	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKN48_RS10080	COG0187	DNA topoisomerase II activity
BKN48_RS10085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKN48_RS10120	COG0517	IMP dehydrogenase activity
BKN48_RS10120	COG0516	GMP reductase activity
BKN48_RS10125	COG1686	Belongs to the peptidase S11 family
BKN48_RS10130	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BKN48_RS10135	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BKN48_RS10140	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BKN48_RS10150	COG1428	Deoxynucleoside kinase
BKN48_RS10155	COG1428	Deoxynucleoside kinase
BKN48_RS10160	COG3858	chitin binding
BKN48_RS10160	COG1388	LysM domain
BKN48_RS10165	COG1335	isochorismatase
BKN48_RS10170	COG0590	tRNA wobble adenosine to inosine editing
BKN48_RS10180	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BKN48_RS10185	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BKN48_RS10190	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BKN48_RS10235	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BKN48_RS10240	COG3853	Toxic anion resistance protein (TelA)
BKN48_RS10245	COG1982	Orn Lys Arg decarboxylase major
BKN48_RS10250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BKN48_RS10255	COG3870	Protein conserved in bacteria
BKN48_RS10260	COG1728	Protein conserved in bacteria
BKN48_RS10265	COG0470	DNA polymerase III
BKN48_RS10270	COG1774	PSP1 C-terminal conserved region
BKN48_RS10275	COG4467	Involved in initiation control of chromosome replication
BKN48_RS10280	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BKN48_RS10285	COG2827	Endonuclease containing a URI domain
BKN48_RS10290	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BKN48_RS10295	COG2002	toxin-antitoxin pair type II binding
BKN48_RS10300	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKN48_RS10300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKN48_RS10305	COG0084	hydrolase, TatD family'
BKN48_RS10310	COG3583	domain protein
BKN48_RS10310	COG3584	3D domain protein
BKN48_RS10315	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BKN48_RS10320	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKN48_RS10330	COG4466	Protein conserved in bacteria
BKN48_RS10340	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BKN48_RS10345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKN48_RS10350	COG0251	oxidation-reduction process
BKN48_RS10355	COG2088	sporulation resulting in formation of a cellular spore
BKN48_RS10365	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BKN48_RS10370	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKN48_RS10375	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BKN48_RS10380	COG0193	aminoacyl-tRNA hydrolase activity
BKN48_RS10390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BKN48_RS10395	COG2002	toxin-antitoxin pair type II binding
BKN48_RS10400	COG2244	polysaccharide biosynthetic process
BKN48_RS10405	COG3956	TIGRFAM MazG family protein
BKN48_RS10410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BKN48_RS10425	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BKN48_RS10430	COG1098	S1 RNA binding domain
BKN48_RS10445	COG2208	phosphoserine phosphatase activity
BKN48_RS10450	COG2304	oxidoreductase activity
BKN48_RS10455	COG0515	serine threonine protein kinase
BKN48_RS10460	COG0037	tRNA processing
BKN48_RS10465	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BKN48_RS10470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKN48_RS10475	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BKN48_RS10480	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BKN48_RS10485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKN48_RS10490	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKN48_RS10495	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BKN48_RS10500	COG0512	Glutamine amidotransferase of anthranilate synthase
BKN48_RS10505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKN48_RS10510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BKN48_RS10515	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BKN48_RS10520	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BKN48_RS10525	COG1396	sequence-specific DNA binding
BKN48_RS10530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BKN48_RS10535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BKN48_RS10615	COG4463	regulation of RNA biosynthetic process
BKN48_RS10620	COG3880	PFAM UvrB UvrC protein
BKN48_RS10625	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BKN48_RS10630	COG0542	response to heat
BKN48_RS10635	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BKN48_RS10640	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BKN48_RS10645	COG4956	integral membrane protein (PIN domain superfamily)
BKN48_RS10650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BKN48_RS10655	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BKN48_RS10660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKN48_RS10670	COG1045	serine acetyltransferase
BKN48_RS10675	COG0215	cysteine-tRNA ligase activity
BKN48_RS10680	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BKN48_RS10685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKN48_RS10690	COG3688	RNA-binding protein containing a PIN domain
BKN48_RS10695	COG1595	DNA-templated transcription, initiation
BKN48_RS10705	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKN48_RS10710	COG0250	Participates in transcription elongation, termination and antitermination
BKN48_RS10720	COG0081	regulation of translation
BKN48_RS10725	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BKN48_RS10735	COG2813	Specifically methylates the guanine in position
BKN48_RS10740	COG0085	RNA polymerase activity
BKN48_RS10745	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BKN48_RS10750	COG1358	cellular component organization or biogenesis
BKN48_RS10755	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BKN48_RS10760	COG0049	tRNA binding
BKN48_RS10765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BKN48_RS10770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BKN48_RS10775	COG0596	Alpha beta hydrolase
BKN48_RS10785	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BKN48_RS10790	COG0088	Forms part of the polypeptide exit tunnel
BKN48_RS10800	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BKN48_RS10815	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BKN48_RS10820	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BKN48_RS10830	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BKN48_RS10835	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BKN48_RS10845	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BKN48_RS10855	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BKN48_RS10860	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BKN48_RS10865	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BKN48_RS10870	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BKN48_RS10880	COG0200	Binds to the 23S rRNA
BKN48_RS10885	COG0201	protein transport
BKN48_RS10890	COG0563	adenylate kinase activity
BKN48_RS10895	COG0024	Methionine aminopeptidase
BKN48_RS10900	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BKN48_RS10910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BKN48_RS10915	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BKN48_RS10920	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BKN48_RS10925	COG0202	RNA polymerase activity
BKN48_RS10930	COG0203	ribosomal protein L17
BKN48_RS10935	COG1122	ATPase activity
BKN48_RS10940	COG1122	ATPase activity
BKN48_RS10945	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BKN48_RS10950	COG0101	tRNA pseudouridine synthase activity
BKN48_RS10955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BKN48_RS10960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BKN48_RS10965	COG2226	methyltransferase
BKN48_RS10975	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKN48_RS10980	COG0489	protein tyrosine kinase activity
BKN48_RS10990	COG2194	sulfuric ester hydrolase activity
BKN48_RS10995	COG0726	polysaccharide deacetylase
BKN48_RS11080	COG0659	secondary active sulfate transmembrane transporter activity
BKN48_RS11085	COG0385	Bile acid
BKN48_RS11090	COG2819	hydrolase of the alpha beta superfamily
BKN48_RS11095	COG2746	aminoglycoside 3-N-acetyltransferase activity
BKN48_RS11100	COG4166	transmembrane transport
BKN48_RS11110	COG1136	(ABC) transporter
BKN48_RS11115	COG2814	Major facilitator Superfamily
BKN48_RS11125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN48_RS11130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN48_RS11135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKN48_RS11140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKN48_RS11140	COG2207	Transcriptional regulator
BKN48_RS11145	COG3876	Protein conserved in bacteria
BKN48_RS11150	COG1472	Belongs to the glycosyl hydrolase 3 family
BKN48_RS11155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKN48_RS11160	COG1263	PTS System
BKN48_RS11160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKN48_RS11165	COG1737	Transcriptional regulator
BKN48_RS11170	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BKN48_RS11175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN48_RS11180	COG1683	Conserved Protein
BKN48_RS11210	COG1595	DNA-templated transcription, initiation
BKN48_RS11215	COG5662	AntiSigma factor
BKN48_RS11220	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BKN48_RS11225	COG4856	YbbR-like protein
BKN48_RS11230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKN48_RS11235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKN48_RS11240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKN48_RS11245	COG3002	Belongs to the UPF0753 family
BKN48_RS11250	COG0288	reversible hydration of carbon dioxide
BKN48_RS11260	COG5609	conserved protein (DUF2294)
BKN48_RS11265	COG0640	Transcriptional regulator
BKN48_RS11270	COG2814	Major facilitator Superfamily
BKN48_RS11285	COG0596	Alpha beta hydrolase
BKN48_RS11290	COG0745	RESPONSE REGULATOR receiver
BKN48_RS11295	COG0642	Histidine kinase
BKN48_RS11305	COG0515	serine threonine protein kinase
BKN48_RS11320	COG1113	amino acid transport
BKN48_RS11335	COG2602	Beta-lactamase
BKN48_RS11340	COG2124	cytochrome p450
BKN48_RS11350	COG0531	amino acid
BKN48_RS11355	COG0584	glycerophosphoryl diester phosphodiesterase
BKN48_RS11360	COG2271	Major facilitator Superfamily
BKN48_RS11370	COG1846	Transcriptional regulator
BKN48_RS11370	COG0456	acetyltransferase
BKN48_RS11375	COG2271	Major facilitator Superfamily
BKN48_RS11385	COG3409	Peptidoglycan-binding domain 1 protein
BKN48_RS11390	COG0697	spore germination
BKN48_RS11395	COG1917	Cupin 2, conserved barrel domain protein
BKN48_RS11395	COG2207	Transcriptional regulator
BKN48_RS11400	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BKN48_RS11405	COG3591	Belongs to the peptidase S1B family
BKN48_RS11415	COG0596	Alpha beta hydrolase
BKN48_RS11420	COG1183	phosphatidylcholine synthase activity
BKN48_RS11425	COG0586	Pfam SNARE associated Golgi protein
BKN48_RS11430	COG0688	phosphatidylethanolamine metabolic process
BKN48_RS11440	COG2312	Erythromycin esterase
BKN48_RS11445	COG1054	Belongs to the UPF0176 family
BKN48_RS11450	COG1301	dicarboxylic acid transport
BKN48_RS11455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKN48_RS11455	COG2190	(PTS) system
BKN48_RS11455	COG1263	PTS System
BKN48_RS11460	COG0363	glucosamine-6-phosphate deaminase activity
BKN48_RS11465	COG2188	Transcriptional regulator
BKN48_RS11475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKN48_RS11480	COG0833	amino acid
BKN48_RS11485	COG2040	homocysteine
BKN48_RS11495	COG1115	amino acid carrier protein
BKN48_RS11500	COG2066	Belongs to the glutaminase family
BKN48_RS11505	COG4191	Histidine kinase
BKN48_RS11510	COG0784	Response regulator, receiver
BKN48_RS11515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKN48_RS11520	COG1012	belongs to the aldehyde dehydrogenase family
BKN48_RS11525	COG2271	Major facilitator Superfamily
BKN48_RS11530	COG4948	Mandelate Racemase Muconate Lactonizing
BKN48_RS11535	COG2186	Transcriptional regulator
BKN48_RS11540	COG2721	sulfolactate sulfo-lyase activity
BKN48_RS11545	COG3173	Aminoglycoside phosphotransferase
BKN48_RS11560	COG0745	RESPONSE REGULATOR receiver
BKN48_RS11565	COG2205	protein histidine kinase activity
BKN48_RS11570	COG1131	(ABC) transporter
BKN48_RS11590	COG3773	Cell wall hydrolase
BKN48_RS11595	COG2304	oxidoreductase activity
BKN48_RS11605	COG3540	Alkaline phosphatase
BKN48_RS11610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKN48_RS11615	COG0805	protein transport
BKN48_RS11620	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BKN48_RS11625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKN48_RS11630	COG0477	Major facilitator Superfamily
BKN48_RS11635	COG1309	transcriptional regulator
BKN48_RS11640	COG0252	asparaginase activity
BKN48_RS11645	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BKN48_RS11650	COG1714	RDD family
BKN48_RS11655	COG1405	negative regulation of cell septum assembly
BKN48_RS11655	COG3012	SEC-C Motif Domain Protein
BKN48_RS11660	COG3290	protein histidine kinase activity
BKN48_RS11665	COG3279	Response regulator of the LytR AlgR family
BKN48_RS11670	COG4555	ABC transporter
BKN48_RS11675	COG1668	transmembrane transport
BKN48_RS11680	COG0667	Aldo Keto reductase
BKN48_RS11690	COG1595	DNA-templated transcription, initiation
BKN48_RS11695	COG1595	DNA-templated transcription, initiation
BKN48_RS11700	COG1876	peptidase activity
BKN48_RS11705	COG0457	Tetratricopeptide repeat
BKN48_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS11715	COG0366	Alpha amylase catalytic
BKN48_RS11720	COG0803	Belongs to the bacterial solute-binding protein 9 family
BKN48_RS11725	COG1121	(ABC) transporter
BKN48_RS11730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKN48_RS11735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN48_RS11740	COG2310	stress, protein
BKN48_RS11745	COG2310	stress, protein
BKN48_RS11750	COG2310	stress, protein
BKN48_RS11755	COG0861	Integral membrane protein TerC family
BKN48_RS11765	COG3853	Toxic anion resistance protein (TelA)
BKN48_RS11770	COG0477	Major facilitator Superfamily
BKN48_RS11780	COG0640	Transcriptional regulator
BKN48_RS11785	COG0517	IMP dehydrogenase activity
BKN48_RS11785	COG4175	Glycine betaine
BKN48_RS11790	COG4176	ABC-type proline glycine betaine transport system permease component
BKN48_RS11795	COG2113	Glycine betaine
BKN48_RS11800	COG1473	amidohydrolase
BKN48_RS11805	COG1288	antiporter activity
BKN48_RS11820	COG0366	Alpha amylase catalytic
BKN48_RS11825	COG0039	L-malate dehydrogenase activity
BKN48_RS11830	COG1620	l-lactate permease
BKN48_RS11835	COG2814	Major facilitator Superfamily
BKN48_RS11840	COG1846	Transcriptional regulator
BKN48_RS11845	COG1280	lysine exporter protein (LysE YggA)
BKN48_RS11850	COG3403	YqcI/YcgG family
BKN48_RS11855	COG1113	amino acid transport
BKN48_RS11860	COG3665	Urea carboxylase-associated protein
BKN48_RS11865	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BKN48_RS11870	COG1660	Displays ATPase and GTPase activities
BKN48_RS11875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKN48_RS11880	COG2226	methyltransferase
BKN48_RS11885	COG0583	DNA-binding transcription factor activity
BKN48_RS11890	COG3458	cephalosporin-C deacetylase activity
BKN48_RS11895	COG3541	Predicted nucleotidyltransferase
BKN48_RS11900	COG0506	proline dehydrogenase activity
BKN48_RS11905	COG1012	belongs to the aldehyde dehydrogenase family
BKN48_RS11910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKN48_RS11915	COG2508	Transcriptional regulator
BKN48_RS11920	COG3689	TIGRFAM TIGR03943 family protein
BKN48_RS11925	COG0701	Predicted permease
BKN48_RS11930	COG2267	carboxylic ester hydrolase activity
BKN48_RS11935	COG0492	ferredoxin-NADP+ reductase activity
BKN48_RS11940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BKN48_RS11940	COG1587	Uroporphyrinogen-III synthase
BKN48_RS11945	COG2146	nitrite reductase [NAD(P)H] activity
BKN48_RS11950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKN48_RS11955	COG0243	molybdopterin cofactor binding
BKN48_RS11960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKN48_RS11965	COG2223	nitrite transmembrane transporter activity
BKN48_RS11970	COG1469	GTP cyclohydrolase I activity
BKN48_RS11975	COG1376	ErfK ybiS ycfS ynhG family protein
BKN48_RS11985	COG0523	cobalamin synthesis protein
BKN48_RS11990	COG0765	amino acid transport
BKN48_RS11995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKN48_RS12005	COG1714	RDD family
BKN48_RS12015	COG2723	6-phospho-beta-galactosidase activity
BKN48_RS12025	COG3209	COG3209 Rhs family protein
BKN48_RS12030	COG0840	transmembrane signaling receptor activity
BKN48_RS12030	COG3290	protein histidine kinase activity
BKN48_RS12035	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BKN48_RS12040	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BKN48_RS12045	COG1733	regulation of RNA biosynthetic process
BKN48_RS12055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN48_RS12060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN48_RS12065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN48_RS12070	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BKN48_RS12075	COG2814	Major facilitator Superfamily
BKN48_RS12085	COG0697	spore germination
BKN48_RS12090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN48_RS12100	COG2364	Membrane
BKN48_RS12105	COG1126	abc transporter atp-binding protein
BKN48_RS12110	COG0765	amino acid transport
BKN48_RS12115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKN48_RS12120	COG0583	DNA-binding transcription factor activity
BKN48_RS12125	COG0163	prenyltransferase activity
BKN48_RS12130	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BKN48_RS12145	COG0596	Alpha beta hydrolase
BKN48_RS12150	COG3104	oligopeptide transport
BKN48_RS12155	COG5434	Belongs to the glycosyl hydrolase 28 family
BKN48_RS12165	COG0697	spore germination
BKN48_RS12175	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BKN48_RS12180	COG1136	(ABC) transporter
BKN48_RS12185	COG0577	efflux transmembrane transporter activity
BKN48_RS12190	COG0745	RESPONSE REGULATOR receiver
BKN48_RS12195	COG3850	Histidine kinase
BKN48_RS12195	COG5002	protein histidine kinase activity
BKN48_RS12200	COG0457	Tetratricopeptide repeat
BKN48_RS12215	COG0527	aspartate kinase activity
BKN48_RS12220	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN48_RS12225	COG4605	iron ion homeostasis
BKN48_RS12230	COG4604	ABC transporter, ATP-binding protein
BKN48_RS12235	COG4607	ABC-type enterochelin transport system periplasmic component
BKN48_RS12240	COG2814	Major facilitator Superfamily
BKN48_RS12245	COG1309	transcriptional regulator
BKN48_RS12250	COG0778	Nitroreductase
BKN48_RS12255	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BKN48_RS12260	COG0640	Transcriptional regulator
BKN48_RS12265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN48_RS12270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BKN48_RS12275	COG1012	belongs to the aldehyde dehydrogenase family
BKN48_RS12280	COG4975	Glucose uptake
BKN48_RS12285	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS12290	COG4549	nuclear export factor GLE1
BKN48_RS12295	COG2372	response to copper ion
BKN48_RS12295	COG1276	copper resistance
BKN48_RS12300	COG1349	DNA-binding transcription factor activity
BKN48_RS12310	COG2213	PTS system mannitol-specific
BKN48_RS12315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKN48_RS12320	COG0246	Mannitol dehydrogenase
BKN48_RS12325	COG0473	3-isopropylmalate dehydrogenase activity
BKN48_RS12330	COG0681	Belongs to the peptidase S26 family
BKN48_RS12335	COG0412	Dienelactone hydrolase
BKN48_RS12340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BKN48_RS12350	COG0561	phosphatase activity
BKN48_RS12355	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BKN48_RS12360	COG1914	H( )-stimulated, divalent metal cation uptake system
BKN48_RS12365	COG4336	lyase activity
BKN48_RS12370	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BKN48_RS12375	COG1984	allophanate hydrolase subunit 2
BKN48_RS12380	COG1414	Transcriptional regulator
BKN48_RS12385	COG2755	lipolytic protein G-D-S-L family
BKN48_RS12395	COG2329	Antibiotic biosynthesis monooxygenase
BKN48_RS12400	COG0768	penicillin binding
BKN48_RS12405	COG4989	oxidoreductase activity
BKN48_RS12410	COG3711	transcriptional antiterminator
BKN48_RS12415	COG0318	PFAM AMP-dependent synthetase and ligase
BKN48_RS12420	COG2226	methyltransferase
BKN48_RS12425	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS12430	COG1917	Cupin 2, conserved barrel domain protein
BKN48_RS12435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN48_RS12440	COG3871	stress protein (general stress protein 26)
BKN48_RS12450	COG2814	Major facilitator Superfamily
BKN48_RS12455	COG1522	sequence-specific DNA binding
BKN48_RS12460	COG0551	DNA topoisomerase type I activity
BKN48_RS12460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKN48_RS12465	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BKN48_RS12470	COG3706	GGDEF domain
BKN48_RS12475	COG5298	Protein conserved in bacteria
BKN48_RS12480	COG1215	transferase activity, transferring glycosyl groups
BKN48_RS12490	COG0531	amino acid
BKN48_RS12495	COG0494	nUDIX hydrolase
BKN48_RS12500	COG0028	Belongs to the TPP enzyme family
BKN48_RS12515	COG1914	H( )-stimulated, divalent metal cation uptake system
BKN48_RS12520	COG2261	transglycosylase associated protein
BKN48_RS12525	COG4876	unkown
BKN48_RS12530	COG2217	Heavy metal translocating P-type atpase
BKN48_RS12535	COG3729	General stress protein
BKN48_RS12540	COG0662	Cupin 2, conserved barrel domain protein
BKN48_RS12545	COG2329	Antibiotic biosynthesis monooxygenase
BKN48_RS12550	COG3546	catalase activity
BKN48_RS12555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKN48_RS12560	COG3290	protein histidine kinase activity
BKN48_RS12565	COG4565	transcriptional regulatory protein
BKN48_RS12570	COG1301	dicarboxylic acid transport
BKN48_RS12575	COG0628	permease
BKN48_RS12585	COG1131	(ABC) transporter
BKN48_RS12590	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BKN48_RS12600	COG1960	acyl-CoA dehydrogenase activity
BKN48_RS12615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BKN48_RS12620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKN48_RS12625	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKN48_RS12630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BKN48_RS12635	COG0513	Belongs to the DEAD box helicase family
BKN48_RS12640	COG3402	PFAM membrane-flanked domain
BKN48_RS12645	COG3428	Bacterial PH domain
BKN48_RS12650	COG0705	Rhomboid family
BKN48_RS12655	COG0736	holo-[acyl-carrier-protein] synthase activity
BKN48_RS12660	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BKN48_RS12665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BKN48_RS12670	COG0864	Transcriptional regulator
BKN48_RS12675	COG2337	Toxic component of a toxin-antitoxin (TA) module
BKN48_RS12680	COG1366	Belongs to the anti-sigma-factor antagonist family
BKN48_RS12685	COG1366	Belongs to the anti-sigma-factor antagonist family
BKN48_RS12690	COG2172	sigma factor antagonist activity
BKN48_RS12695	COG2208	phosphoserine phosphatase activity
BKN48_RS12700	COG1366	Belongs to the anti-sigma-factor antagonist family
BKN48_RS12705	COG2172	sigma factor antagonist activity
BKN48_RS12710	COG1191	sigma factor activity
BKN48_RS12715	COG2208	phosphoserine phosphatase activity
BKN48_RS12730	COG1673	EVE domain
BKN48_RS12735	COG1846	Transcriptional regulator
BKN48_RS12740	COG2183	response to ionizing radiation
BKN48_RS12750	COG3091	SprT-like family
BKN48_RS12790	COG0582	viral genome integration into host DNA
BKN48_RS12795	COG0457	Tetratricopeptide repeat
BKN48_RS12805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN48_RS12810	COG1522	sequence-specific DNA binding
BKN48_RS12815	COG1522	sequence-specific DNA binding
BKN48_RS12820	COG1335	isochorismatase
BKN48_RS12825	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BKN48_RS12830	COG2814	Major facilitator Superfamily
BKN48_RS12850	COG5444	nuclease activity
BKN48_RS12865	COG1278	Cold shock
BKN48_RS12870	COG1329	Transcriptional regulator
BKN48_RS12875	COG1917	Cupin 2, conserved barrel domain protein
BKN48_RS12875	COG2207	Transcriptional regulator
BKN48_RS12880	COG0697	spore germination
BKN48_RS12885	COG2207	Transcriptional regulator
BKN48_RS12885	COG3708	Transcriptional regulator
BKN48_RS12890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN48_RS12895	COG0477	Major facilitator Superfamily
BKN48_RS12905	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BKN48_RS12915	COG0697	spore germination
BKN48_RS12920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN48_RS12925	COG2030	dehydratase
BKN48_RS12930	COG3545	Serine hydrolase
BKN48_RS12935	COG1733	regulation of RNA biosynthetic process
BKN48_RS12940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKN48_RS12945	COG0640	Transcriptional regulator
BKN48_RS12950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BKN48_RS12960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN48_RS12965	COG1316	TRANSCRIPTIONal
BKN48_RS12980	COG5002	protein histidine kinase activity
BKN48_RS12985	COG0745	RESPONSE REGULATOR receiver
BKN48_RS12990	COG0697	spore germination
BKN48_RS12995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN48_RS13000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BKN48_RS13005	COG0640	Transcriptional regulator
BKN48_RS13010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKN48_RS13020	COG4585	Histidine kinase
BKN48_RS13025	COG2197	response regulator
BKN48_RS13030	COG2409	Drug exporters of the RND superfamily
BKN48_RS13035	COG1811	Na channel or pump
BKN48_RS13040	COG0789	Transcriptional regulator
BKN48_RS13040	COG4978	Transcriptional regulator
BKN48_RS13045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BKN48_RS13050	COG0778	Nitroreductase
BKN48_RS13055	COG0346	lactoylglutathione lyase activity
BKN48_RS13060	COG2259	Doxx family
BKN48_RS13065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKN48_RS13090	COG2323	membrane
BKN48_RS13095	COG0071	Belongs to the small heat shock protein (HSP20) family
BKN48_RS13110	COG1309	transcriptional regulator
BKN48_RS13120	COG0456	acetyltransferase
BKN48_RS13125	COG0488	(ABC) transporter
BKN48_RS13130	COG1113	amino acid transport
BKN48_RS13135	COG2318	DinB family
BKN48_RS13140	COG1846	Transcriptional regulator
BKN48_RS13145	COG2409	Drug exporters of the RND superfamily
BKN48_RS13145	COG1033	growth of symbiont in host cell
BKN48_RS13150	COG0778	Nitroreductase
BKN48_RS13155	COG1846	Transcriptional regulator
BKN48_RS13160	COG2814	Major facilitator Superfamily
BKN48_RS13165	COG0730	response to heat
BKN48_RS13170	COG1802	Transcriptional regulator
BKN48_RS13175	COG1388	LysM domain
BKN48_RS13175	COG3858	chitin binding
BKN48_RS13180	COG1819	glycosyl
BKN48_RS13190	COG1785	Belongs to the alkaline phosphatase family
BKN48_RS13195	COG5646	InterPro IPR014922
BKN48_RS13205	COG0454	-acetyltransferase
BKN48_RS13210	COG1078	dGTPase activity
BKN48_RS13215	COG1388	LysM domain
BKN48_RS13220	COG2814	Major facilitator Superfamily
BKN48_RS13225	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKN48_RS13230	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKN48_RS13235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKN48_RS13240	COG2723	6-phospho-beta-galactosidase activity
BKN48_RS13245	COG2188	Transcriptional regulator
BKN48_RS13250	COG1940	carbohydrate kinase activity
BKN48_RS13255	COG1482	cell wall glycoprotein biosynthetic process
BKN48_RS13260	COG4124	Belongs to the glycosyl hydrolase 26 family
BKN48_RS13305	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BKN48_RS13310	COG0802	atpase or kinase
BKN48_RS13315	COG1214	PFAM Peptidase M22, glycoprotease
BKN48_RS13320	COG0456	acetyltransferase
BKN48_RS13325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BKN48_RS13330	COG0488	(ABC) transporter
BKN48_RS13335	COG0315	cyclic pyranopterin monophosphate synthase activity
BKN48_RS13340	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BKN48_RS13345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKN48_RS13350	COG0805	protein transport
BKN48_RS13360	COG1266	CAAX protease self-immunity
BKN48_RS13370	COG0459	protein refolding
BKN48_RS13410	COG0457	Tetratricopeptide repeat
BKN48_RS13415	COG1063	alcohol dehydrogenase
BKN48_RS13420	COG2211	Major facilitator Superfamily
BKN48_RS13425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKN48_RS13430	COG1842	Phage shock protein A
BKN48_RS13435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BKN48_RS13440	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BKN48_RS13445	COG4260	virion core protein, lumpy skin disease virus
BKN48_RS13455	COG2814	Major facilitator Superfamily
BKN48_RS13460	COG1063	alcohol dehydrogenase
BKN48_RS13465	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BKN48_RS13470	COG0823	Involved in the tonB-independent uptake of proteins
BKN48_RS13485	COG2267	carboxylic ester hydrolase activity
BKN48_RS13495	COG2132	Multicopper oxidase
BKN48_RS13500	COG1113	amino acid transport
BKN48_RS13510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BKN48_RS13515	COG0714	Associated with various cellular activities
BKN48_RS13520	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BKN48_RS13525	COG1305	Transglutaminase-like
BKN48_RS13530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKN48_RS13530	COG0519	Catalyzes the synthesis of GMP from XMP
BKN48_RS13545	COG2252	PERMEase
BKN48_RS13550	COG3064	Membrane
BKN48_RS13560	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BKN48_RS13570	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BKN48_RS13575	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BKN48_RS13580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKN48_RS13585	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BKN48_RS13590	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKN48_RS13595	COG0047	phosphoribosylformylglycinamidine synthase activity
BKN48_RS13600	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKN48_RS13605	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BKN48_RS13610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BKN48_RS13615	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BKN48_RS13620	COG0138	bifunctional purine biosynthesis protein purh
BKN48_RS13625	COG0151	Belongs to the GarS family
BKN48_RS13630	COG1522	sequence-specific DNA binding
BKN48_RS13635	COG0531	amino acid
BKN48_RS13645	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BKN48_RS13650	COG1470	cell adhesion involved in biofilm formation
BKN48_RS13655	COG4496	protein, YerC YecD
BKN48_RS13660	COG0069	glutamate synthase activity
BKN48_RS13670	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BKN48_RS13675	COG0210	DNA helicase
BKN48_RS13680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKN48_RS13685	COG4851	CamS sex pheromone cAM373 precursor
BKN48_RS13690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKN48_RS13695	COG1285	pathogenesis
BKN48_RS13700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKN48_RS13705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKN48_RS13710	COG0154	amidase activity
BKN48_RS13715	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKN48_RS13720	COG1309	transcriptional regulator
BKN48_RS13725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKN48_RS13730	COG1597	lipid kinase activity
BKN48_RS13735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKN48_RS13755	COG5444	nuclease activity
BKN48_RS13765	COG3586	endonuclease activity
BKN48_RS13770	COG3391	amine dehydrogenase activity
BKN48_RS13780	COG0457	Tetratricopeptide repeat
BKN48_RS13790	COG0217	transcriptional regulatory protein
BKN48_RS13800	COG1309	transcriptional regulator
BKN48_RS13805	COG3631	Ketosteroid isomerase-related protein
BKN48_RS13810	COG0702	epimerase
BKN48_RS13825	COG3546	catalase activity
BKN48_RS13830	COG0454	-acetyltransferase
BKN48_RS13840	COG5578	integral membrane protein
BKN48_RS13845	COG2972	Histidine kinase
BKN48_RS13850	COG4753	response regulator
BKN48_RS13850	COG2207	Transcriptional regulator
BKN48_RS13855	COG1653	transport
BKN48_RS13860	COG1175	transmembrane transport
BKN48_RS13865	COG0395	ABC-type sugar transport system, permease component
BKN48_RS13870	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BKN48_RS13875	COG2207	Transcriptional regulator
BKN48_RS13880	COG2755	lipolytic protein G-D-S-L family
BKN48_RS13890	COG5578	integral membrane protein
BKN48_RS13895	COG3401	FG-GAP repeat protein
BKN48_RS13900	COG3401	FG-GAP repeat protein
BKN48_RS13905	COG2755	lipolytic protein G-D-S-L family
BKN48_RS13910	COG1874	Beta-galactosidase
BKN48_RS13920	COG1653	transport
BKN48_RS13925	COG4209	transmembrane transport
BKN48_RS13930	COG0395	ABC-type sugar transport system, permease component
BKN48_RS13935	COG1486	melibiose metabolic process
BKN48_RS13940	COG2323	membrane
BKN48_RS13945	COG2329	Antibiotic biosynthesis monooxygenase
BKN48_RS13950	COG0346	lactoylglutathione lyase activity
BKN48_RS13965	COG5583	Uncharacterized small protein (DUF2292)
BKN48_RS13970	COG0670	Belongs to the BI1 family
BKN48_RS13975	COG1846	Transcriptional regulator
BKN48_RS13980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN48_RS13995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BKN48_RS13995	COG2124	cytochrome p450
BKN48_RS14000	COG1368	sulfuric ester hydrolase activity
BKN48_RS14005	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BKN48_RS14010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKN48_RS14015	COG1442	glycosyl transferase family 8
BKN48_RS14020	COG1216	Glycosyl transferase, family 2
BKN48_RS14025	COG1442	glycosyl transferase family 8
BKN48_RS14030	COG2223	nitrite transmembrane transporter activity
BKN48_RS14035	COG1011	Hydrolase
BKN48_RS14040	COG0531	amino acid
BKN48_RS14045	COG1012	belongs to the aldehyde dehydrogenase family
BKN48_RS14050	COG0840	transmembrane signaling receptor activity
BKN48_RS14055	COG0488	(ABC) transporter
BKN48_RS14065	COG0789	Transcriptional regulator
BKN48_RS14070	COG2814	Major facilitator Superfamily
BKN48_RS14075	COG1404	Belongs to the peptidase S8 family
BKN48_RS14090	COG0488	(ABC) transporter
BKN48_RS14095	COG0513	Belongs to the DEAD box helicase family
BKN48_RS14100	COG0456	acetyltransferase
BKN48_RS14105	COG2130	NADP-dependent
BKN48_RS14110	COG1120	ATPase activity
BKN48_RS14115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN48_RS14120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN48_RS14125	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BKN48_RS14140	COG3866	Pectate lyase
BKN48_RS14145	COG0471	metal ion transport
BKN48_RS14150	COG3290	protein histidine kinase activity
BKN48_RS14155	COG4565	transcriptional regulatory protein
BKN48_RS14160	COG3181	Tripartite tricarboxylate transporter family receptor
BKN48_RS14170	COG2851	Citrate transporter
BKN48_RS14175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN48_RS14180	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BKN48_RS14185	COG1254	Belongs to the acylphosphatase family
BKN48_RS14190	COG2258	MOSC domain
BKN48_RS14210	COG0024	Methionine aminopeptidase
BKN48_RS14215	COG1263	PTS System
BKN48_RS14215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKN48_RS14220	COG1368	sulfuric ester hydrolase activity
BKN48_RS14230	COG1115	amino acid carrier protein
BKN48_RS14235	COG0531	amino acid
BKN48_RS14250	COG0697	spore germination
BKN48_RS14255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKN48_RS14255	COG1263	PTS System
BKN48_RS14260	COG0366	Alpha amylase catalytic
BKN48_RS14265	COG2188	Transcriptional regulator
BKN48_RS14270	COG0778	Nitroreductase
BKN48_RS14275	COG0737	Belongs to the 5'-nucleotidase family
BKN48_RS14280	COG0693	protein deglycase activity
BKN48_RS14285	COG2814	Major facilitator Superfamily
BKN48_RS14290	COG4840	Belongs to the UPF0435 family
BKN48_RS14295	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKN48_RS14300	COG4980	gas vesicle protein
BKN48_RS14305	COG1295	ribonuclease BN
BKN48_RS14315	COG0477	Major facilitator Superfamily
BKN48_RS14325	COG0387	Pfam Sodium calcium exchanger
BKN48_RS14335	COG0668	transmembrane transport
BKN48_RS14340	COG0535	radical SAM domain protein
BKN48_RS14350	COG0726	polysaccharide deacetylase
BKN48_RS14355	COG2084	Dehydrogenase
BKN48_RS14360	COG0598	Magnesium transport protein CorA
BKN48_RS14365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BKN48_RS14370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKN48_RS14380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BKN48_RS14385	COG4637	Psort location Cytoplasmic, score
BKN48_RS14395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKN48_RS14400	COG0022	dehydrogenase e1 component
BKN48_RS14405	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKN48_RS14410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKN48_RS14415	COG3284	Transcriptional regulator
BKN48_RS14425	COG1742	UPF0060 membrane protein
BKN48_RS14450	COG4842	Belongs to the WXG100 family
BKN48_RS14455	COG1486	melibiose metabolic process
BKN48_RS14460	COG1737	Transcriptional regulator
BKN48_RS14465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKN48_RS14465	COG1263	PTS System
BKN48_RS14475	COG1132	(ABC) transporter
BKN48_RS14480	COG2259	Doxx family
BKN48_RS14485	COG2514	catechol 2,3-dioxygenase activity
BKN48_RS14490	COG4585	Histidine kinase
BKN48_RS14495	COG2197	response regulator
BKN48_RS14500	COG1131	(ABC) transporter
BKN48_RS14505	COG0842	Transport permease protein
BKN48_RS14505	COG1511	domain protein
BKN48_RS14510	COG0842	Transport permease protein
BKN48_RS14515	COG1695	Transcriptional regulator
BKN48_RS14520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BKN48_RS14525	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BKN48_RS14530	COG2318	DinB family
BKN48_RS14535	COG2814	Major facilitator Superfamily
BKN48_RS14540	COG1846	Transcriptional regulator
BKN48_RS14545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BKN48_RS14545	COG0392	lysyltransferase activity
BKN48_RS14550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKN48_RS14555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN48_RS14560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKN48_RS14565	COG0384	phenazine biosynthesis protein PhzF
BKN48_RS14570	COG0778	Nitroreductase
BKN48_RS14585	COG1090	epimerase
BKN48_RS14590	COG2137	regulation of response to DNA damage stimulus
BKN48_RS14605	COG2814	Major facilitator Superfamily
BKN48_RS14620	COG3103	Sh3 type 3 domain protein
BKN48_RS14625	COG5658	integral membrane protein
BKN48_RS14630	COG0596	Alpha beta hydrolase
BKN48_RS14635	COG0463	Glycosyl transferase, family 2
BKN48_RS14640	COG4485	Bacterial membrane protein, YfhO
BKN48_RS14645	COG1988	membrane-bound metal-dependent
BKN48_RS14650	COG1194	a g-specific adenine glycosylase
BKN48_RS14660	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS14675	COG3557	Belongs to the UPF0374 family
BKN48_RS14680	COG1132	(ABC) transporter
BKN48_RS14685	COG4129	membrane
BKN48_RS14690	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKN48_RS14695	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BKN48_RS14700	COG0735	belongs to the Fur family
BKN48_RS14815	COG4326	sporulation control protein
BKN48_RS14825	COG5577	PFAM Coat F domain
BKN48_RS14830	COG3340	Belongs to the peptidase S51 family
BKN48_RS14835	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BKN48_RS14845	COG0753	catalase activity
BKN48_RS14850	COG1116	anion transmembrane transporter activity
BKN48_RS14855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKN48_RS14860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKN48_RS14865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKN48_RS14875	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BKN48_RS14885	COG1476	TRANSCRIPTIONal
BKN48_RS14895	COG3382	B3 4 domain protein
BKN48_RS14900	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BKN48_RS14910	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BKN48_RS14915	COG0789	Transcriptional regulator
BKN48_RS14920	COG1664	Polymer-forming cytoskeletal
BKN48_RS14925	COG1664	Polymer-forming cytoskeletal
BKN48_RS14930	COG2766	serine protein kinase
BKN48_RS14935	COG2718	Belongs to the UPF0229 family
BKN48_RS14945	COG1846	Transcriptional regulator
BKN48_RS14950	COG1566	PFAM secretion protein HlyD family protein
BKN48_RS14955	COG2814	Major facilitator Superfamily
BKN48_RS14960	COG0655	NAD(P)H dehydrogenase (quinone) activity
BKN48_RS14975	COG1725	Transcriptional regulator
BKN48_RS14990	COG1278	Cold shock
BKN48_RS14995	COG1464	Belongs to the NlpA lipoprotein family
BKN48_RS15000	COG3706	GGDEF domain
BKN48_RS15005	COG1823	symporter activity
BKN48_RS15010	COG5444	nuclease activity
BKN48_RS15040	COG5577	PFAM Coat F domain
BKN48_RS15045	COG0737	Belongs to the 5'-nucleotidase family
BKN48_RS15045	COG1525	nuclease
BKN48_RS15045	COG4085	toxin activity
BKN48_RS15050	COG3764	Sortase (surface protein transpeptidase)
BKN48_RS15055	COG0564	pseudouridine synthase activity
BKN48_RS15065	COG0517	IMP dehydrogenase activity
BKN48_RS15070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKN48_RS15075	COG3153	acetyltransferase
BKN48_RS15075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKN48_RS15080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BKN48_RS15085	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BKN48_RS15090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BKN48_RS15095	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKN48_RS15100	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BKN48_RS15105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKN48_RS15110	COG4585	Histidine kinase
BKN48_RS15110	COG2203	Gaf domain
BKN48_RS15115	COG2197	response regulator
BKN48_RS15120	COG0431	NADPH-dependent FMN reductase
BKN48_RS15135	COG0791	NLP P60 protein
BKN48_RS15135	COG1388	LysM domain
BKN48_RS15140	COG1959	2 iron, 2 sulfur cluster binding
BKN48_RS15145	COG0668	transmembrane transport
BKN48_RS15150	COG2719	SpoVR family
BKN48_RS15155	COG1785	Belongs to the alkaline phosphatase family
BKN48_RS15160	COG0791	NLP P60 protein
BKN48_RS15160	COG1388	LysM domain
BKN48_RS15165	COG0583	DNA-binding transcription factor activity
BKN48_RS15170	COG0372	Belongs to the citrate synthase family
BKN48_RS15175	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS15180	COG0531	amino acid
BKN48_RS15185	COG0733	neurotransmitter:sodium symporter activity
BKN48_RS15190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BKN48_RS15195	COG0456	acetyltransferase
BKN48_RS15210	COG1595	DNA-templated transcription, initiation
BKN48_RS15215	COG0667	Aldo Keto reductase
BKN48_RS15220	COG0204	Acyl-transferase
BKN48_RS15225	COG1253	flavin adenine dinucleotide binding
BKN48_RS15230	COG0789	Transcriptional regulator
BKN48_RS15235	COG0436	Aminotransferase
BKN48_RS15240	COG1253	flavin adenine dinucleotide binding
BKN48_RS15245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKN48_RS15250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKN48_RS15255	COG0584	glycerophosphoryl diester phosphodiesterase
BKN48_RS15265	COG0668	transmembrane transport
BKN48_RS15270	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKN48_RS15275	COG0726	polysaccharide deacetylase
BKN48_RS15280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKN48_RS15285	COG1757	Na H antiporter
BKN48_RS15290	COG0589	response to stress
BKN48_RS15300	COG1132	(ABC) transporter
BKN48_RS15305	COG1132	(ABC) transporter
BKN48_RS15310	COG0702	epimerase
BKN48_RS15325	COG0189	ligase activity
BKN48_RS15330	COG0189	ligase activity
BKN48_RS15335	COG4399	Belongs to the UPF0754 family
BKN48_RS15340	COG3679	Belongs to the UPF0342 family
BKN48_RS15345	COG4335	DNA alkylation repair
BKN48_RS15350	COG0561	phosphatase activity
BKN48_RS15355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKN48_RS15360	COG0475	glutathione-regulated potassium exporter activity
BKN48_RS15365	COG0490	domain, Protein
BKN48_RS15375	COG1024	Enoyl-CoA hydratase
BKN48_RS15385	COG4152	abc transporter atp-binding protein
BKN48_RS15390	COG1668	transmembrane transport
BKN48_RS15400	COG0420	3'-5' exonuclease activity
BKN48_RS15405	COG4717	serine-type aminopeptidase activity
BKN48_RS15410	COG3481	metal-dependent phosphohydrolase, HD sub domain
BKN48_RS15420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKN48_RS15440	COG1846	Transcriptional regulator
BKN48_RS15445	COG4980	gas vesicle protein
BKN48_RS15460	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BKN48_RS15465	COG0537	adenosine 5'-monophosphoramidase activity
BKN48_RS15470	COG1131	(ABC) transporter
BKN48_RS15475	COG4473	ABC transporter
BKN48_RS15485	COG1473	amidohydrolase
BKN48_RS15490	COG3069	C4-dicarboxylate transmembrane transporter activity
BKN48_RS15500	COG2329	Antibiotic biosynthesis monooxygenase
BKN48_RS15505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKN48_RS15510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BKN48_RS15515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BKN48_RS15520	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BKN48_RS15525	COG1309	transcriptional regulator
BKN48_RS15530	COG1511	domain protein
BKN48_RS15535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKN48_RS15540	COG4377	Putative membrane peptidase family (DUF2324)
BKN48_RS15550	COG1363	Peptidase, m42
BKN48_RS15555	COG4405	Protein conserved in bacteria
BKN48_RS15560	COG1301	dicarboxylic acid transport
BKN48_RS15570	COG1234	tRNA 3'-trailer cleavage
BKN48_RS15575	COG0095	Lipoate-protein ligase
BKN48_RS15580	COG0702	epimerase
BKN48_RS15585	COG0318	PFAM AMP-dependent synthetase and ligase
BKN48_RS15595	COG0501	Belongs to the peptidase M48B family
BKN48_RS15605	COG0456	acetyltransferase
BKN48_RS15610	COG0604	alcohol dehydrogenase
BKN48_RS15615	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BKN48_RS15620	COG0406	alpha-ribazole phosphatase activity
BKN48_RS15625	COG0183	Belongs to the thiolase family
BKN48_RS15630	COG0318	PFAM AMP-dependent synthetase and ligase
BKN48_RS15635	COG1268	BioY protein
BKN48_RS15640	COG0840	transmembrane signaling receptor activity
BKN48_RS15645	COG0723	plastoquinol--plastocyanin reductase activity
BKN48_RS15645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKN48_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS15660	COG4903	ComK protein
BKN48_RS15665	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS15675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKN48_RS15690	COG0398	Pfam SNARE associated Golgi protein
BKN48_RS15695	COG0681	Belongs to the peptidase S26 family
BKN48_RS15700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKN48_RS15705	COG1846	Transcriptional regulator
BKN48_RS15720	COG0738	Major facilitator superfamily
BKN48_RS15725	COG0673	inositol 2-dehydrogenase activity
BKN48_RS15730	COG0561	phosphatase activity
BKN48_RS15735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKN48_RS15740	COG1609	Transcriptional regulator
BKN48_RS15745	COG3180	Ammonia monooxygenase
BKN48_RS15750	COG2814	Major facilitator Superfamily
BKN48_RS15750	COG0477	Major facilitator Superfamily
BKN48_RS15755	COG4533	DNA binding
BKN48_RS15765	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BKN48_RS15770	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BKN48_RS15775	COG1074	ATP-dependent DNA helicase activity
BKN48_RS15780	COG0420	3'-5' exonuclease activity
BKN48_RS15785	COG0419	ATPase involved in DNA repair
BKN48_RS15790	COG1403	HNH endonuclease
BKN48_RS15835	COG5337	Spore coat protein CotH
BKN48_RS15840	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKN48_RS15850	COG1404	Belongs to the peptidase S8 family
BKN48_RS15860	COG0367	asparagine synthase
BKN48_RS15865	COG2318	DinB family
BKN48_RS15870	COG1562	ergosterol biosynthetic process
BKN48_RS15875	COG0534	Mate efflux family protein
BKN48_RS15880	COG1917	Cupin 2, conserved barrel domain protein
BKN48_RS15880	COG2207	Transcriptional regulator
BKN48_RS15885	COG1609	Transcriptional regulator
BKN48_RS15890	COG0673	inositol 2-dehydrogenase activity
BKN48_RS15895	COG2318	DinB family
BKN48_RS15900	COG1279	arginine transmembrane transporter activity
BKN48_RS15910	COG1357	PFAM Pentapeptide repeats (8 copies)
BKN48_RS15915	COG2267	carboxylic ester hydrolase activity
BKN48_RS15920	COG0529	Catalyzes the synthesis of activated sulfate
BKN48_RS15925	COG2046	Belongs to the sulfate adenylyltransferase family
BKN48_RS15930	COG0175	sulfate reduction
BKN48_RS15935	COG2045	Belongs to the ComB family
BKN48_RS15940	COG1809	phosphosulfolactate synthase activity
BKN48_RS15945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKN48_RS15950	COG4948	Mandelate Racemase Muconate Lactonizing
BKN48_RS15955	COG2814	Major facilitator Superfamily
BKN48_RS15960	COG0454	-acetyltransferase
BKN48_RS15965	COG2153	protein acetylation
BKN48_RS15970	COG0646	methionine synthase
BKN48_RS15970	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BKN48_RS15975	COG1666	GTP binding
BKN48_RS15980	COG2996	Protein conserved in bacteria
BKN48_RS16000	COG1695	Transcriptional regulator
BKN48_RS16015	COG3227	Zinc metalloprotease (Elastase)
BKN48_RS16020	COG1307	EDD domain protein, DegV family
BKN48_RS16025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKN48_RS16045	COG0561	phosphatase activity
BKN48_RS16050	COG1073	alpha beta
BKN48_RS16055	COG2151	metal-sulfur cluster biosynthetic enzyme
BKN48_RS16065	COG0277	FAD linked oxidase domain protein
BKN48_RS16070	COG2271	Major facilitator Superfamily
BKN48_RS16075	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BKN48_RS16080	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BKN48_RS16090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKN48_RS16095	COG0505	Belongs to the CarA family
BKN48_RS16100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKN48_RS16105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKN48_RS16120	COG2267	carboxylic ester hydrolase activity
BKN48_RS16130	COG1744	ABC transporter substrate-binding protein PnrA-like
BKN48_RS16145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKN48_RS16150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKN48_RS16155	COG5504	Zn-dependent protease
BKN48_RS16160	COG0444	Belongs to the ABC transporter superfamily
BKN48_RS16165	COG4608	Belongs to the ABC transporter superfamily
BKN48_RS16175	COG0601	transmembrane transport
BKN48_RS16180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKN48_RS16190	COG0180	Tryptophanyl-tRNA synthetase
BKN48_RS16195	COG4166	transmembrane transport
BKN48_RS16200	COG0601	transmembrane transport
BKN48_RS16205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKN48_RS16210	COG0444	Belongs to the ABC transporter superfamily
BKN48_RS16215	COG4608	Belongs to the ABC transporter superfamily
BKN48_RS16220	COG2814	Major facilitator Superfamily
BKN48_RS16225	COG0456	acetyltransferase
BKN48_RS16230	COG1393	Belongs to the ArsC family
BKN48_RS16235	COG0861	Integral membrane protein TerC family
BKN48_RS16240	COG4862	establishment of competence for transformation
BKN48_RS16245	COG4469	Competence protein
BKN48_RS16250	COG1164	Oligoendopeptidase f
BKN48_RS16265	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BKN48_RS16270	COG2346	COG2346, Truncated hemoglobins
BKN48_RS16275	COG0741	lytic transglycosylase activity
BKN48_RS16280	COG4116	CYTH
BKN48_RS16290	COG2357	RelA SpoT domain protein
BKN48_RS16295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKN48_RS16300	COG0564	pseudouridine synthase activity
BKN48_RS16305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BKN48_RS16310	COG0569	domain protein
BKN48_RS16310	COG0475	glutathione-regulated potassium exporter activity
BKN48_RS16315	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BKN48_RS16320	COG0352	thiamine-phosphate diphosphorylase activity
BKN48_RS16325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKN48_RS16330	COG2104	thiamine diphosphate biosynthetic process
BKN48_RS16335	COG2022	thiamine diphosphate biosynthetic process
BKN48_RS16340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKN48_RS16345	COG0351	phosphomethylpyrimidine kinase
BKN48_RS16350	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BKN48_RS16410	COG0210	DNA helicase
BKN48_RS16420	COG2153	protein acetylation
BKN48_RS16425	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BKN48_RS16430	COG2382	esterase
BKN48_RS16435	COG0626	cystathionine gamma-synthase activity
BKN48_RS16440	COG0626	cystathionine gamma-synthase activity
BKN48_RS16445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN48_RS16450	COG5505	Protein of unknown function (DUF819)
BKN48_RS16480	COG5444	nuclease activity
BKN48_RS16505	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BKN48_RS16510	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS16520	COG3711	transcriptional antiterminator
BKN48_RS16520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKN48_RS16525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKN48_RS16525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKN48_RS16525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKN48_RS16530	COG1482	cell wall glycoprotein biosynthetic process
BKN48_RS16540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN48_RS16550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BKN48_RS16565	COG0109	protoheme IX farnesyltransferase activity
BKN48_RS16575	COG0726	polysaccharide deacetylase
BKN48_RS16595	COG5504	Zn-dependent protease
BKN48_RS16600	COG2205	protein histidine kinase activity
BKN48_RS16610	COG3383	formate dehydrogenase (NAD+) activity
BKN48_RS16615	COG2427	Protein of unknown function (DUF1641)
BKN48_RS16625	COG1051	belongs to the nudix hydrolase family
BKN48_RS16635	COG2124	cytochrome p450
BKN48_RS16640	COG1819	glycosyl
BKN48_RS16650	COG1587	Uroporphyrinogen-III synthase
BKN48_RS16655	COG0390	transport system, permease component
BKN48_RS16660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKN48_RS16665	COG0697	spore germination
BKN48_RS16670	COG4297	protein containing double-stranded beta helix domain
BKN48_RS16680	COG1252	NADH dehydrogenase
BKN48_RS16685	COG1904	glucuronate isomerase
BKN48_RS16690	COG2211	Major facilitator Superfamily
BKN48_RS16695	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BKN48_RS16700	COG1063	alcohol dehydrogenase
BKN48_RS16705	COG1312	Catalyzes the dehydration of D-mannonate
BKN48_RS16710	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS16715	COG2271	Major facilitator Superfamily
BKN48_RS16720	COG1609	Transcriptional regulator
BKN48_RS16725	COG0246	Mannitol dehydrogenase
BKN48_RS16730	COG2721	sulfolactate sulfo-lyase activity
BKN48_RS16735	COG0730	response to heat
BKN48_RS16740	COG2318	DinB family
BKN48_RS16745	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKN48_RS16750	COG0457	Tetratricopeptide repeat
BKN48_RS16760	COG2350	Protein conserved in bacteria
BKN48_RS16765	COG5632	N-Acetylmuramoyl-L-alanine amidase
BKN48_RS16765	COG1388	LysM domain
BKN48_RS16765	COG3409	Peptidoglycan-binding domain 1 protein
BKN48_RS16775	COG4195	phage-related replication protein
BKN48_RS16780	COG3546	catalase activity
BKN48_RS16785	COG2856	Zn peptidase
BKN48_RS16790	COG1396	sequence-specific DNA binding
BKN48_RS16800	COG1522	sequence-specific DNA binding
BKN48_RS16805	COG1484	DNA-dependent DNA replication
BKN48_RS16830	COG1595	DNA-templated transcription, initiation
BKN48_RS16835	COG5484	DNA packaging
BKN48_RS16835	COG3728	DNA packaging
BKN48_RS16840	COG1783	phage Terminase large subunit
BKN48_RS16845	COG5518	Phage portal protein
BKN48_RS16850	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BKN48_RS16855	COG4653	Phage capsid family
BKN48_RS16905	COG3953	SLT domain
BKN48_RS16905	COG5412	phage tail tape measure protein
BKN48_RS16905	COG3953	SLT domain
BKN48_RS16905	COG5412	phage tail tape measure protein
BKN48_RS16910	COG1652	LysM domain
BKN48_RS16915	COG4193	domain, Protein
BKN48_RS16925	COG3628	GPW Gp25 family protein
BKN48_RS16930	COG3299	homolog of phage Mu protein gp47
BKN48_RS16935	COG3778	Protein conserved in bacteria
BKN48_RS16975	COG3409	Peptidoglycan-binding domain 1 protein
BKN48_RS16975	COG5632	N-Acetylmuramoyl-L-alanine amidase
BKN48_RS16990	COG0306	phosphate transporter
BKN48_RS16995	COG1392	Phosphate transport regulator
BKN48_RS17000	COG0531	amino acid
BKN48_RS17005	COG0346	lactoylglutathione lyase activity
BKN48_RS17010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BKN48_RS17015	COG0463	Glycosyl transferase, family 2
BKN48_RS17025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKN48_RS17035	COG2362	D-Aminopeptidase
BKN48_RS17040	COG0601	transmembrane transport
BKN48_RS17045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKN48_RS17050	COG0444	Belongs to the ABC transporter superfamily
BKN48_RS17055	COG4166	transmembrane transport
BKN48_RS17060	COG1619	proteins homologs of microcin C7 resistance protein MccF
BKN48_RS17065	COG4948	Mandelate Racemase Muconate Lactonizing
BKN48_RS17070	COG0791	NLP P60 protein
BKN48_RS17075	COG4608	Belongs to the ABC transporter superfamily
BKN48_RS17080	COG2706	6-phosphogluconolactonase activity
BKN48_RS17085	COG1834	amidinotransferase
BKN48_RS17090	COG1607	acyl-coa hydrolase
BKN48_RS17095	COG1017	nitric oxide dioxygenase activity
BKN48_RS17095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKN48_RS17105	COG2323	membrane
BKN48_RS17110	COG2318	DinB family
BKN48_RS17115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN48_RS17120	COG2076	Multidrug Resistance protein
BKN48_RS17125	COG2076	Multidrug Resistance protein
BKN48_RS17130	COG0788	formyltetrahydrofolate deformylase activity
BKN48_RS17135	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BKN48_RS17140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BKN48_RS17145	COG1764	response to oxidative stress
BKN48_RS17150	COG1846	Transcriptional regulator
BKN48_RS17155	COG1764	response to oxidative stress
BKN48_RS17165	COG0590	tRNA wobble adenosine to inosine editing
BKN48_RS17170	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKN48_RS17175	COG1404	Belongs to the peptidase S8 family
BKN48_RS17180	COG1366	Belongs to the anti-sigma-factor antagonist family
BKN48_RS17185	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BKN48_RS17190	COG1122	ATPase activity
BKN48_RS17195	COG4721	ABC-type cobalt transport system, permease component
BKN48_RS17205	COG0745	RESPONSE REGULATOR receiver
BKN48_RS17210	COG5002	protein histidine kinase activity
BKN48_RS17210	COG3850	Histidine kinase
BKN48_RS17215	COG3212	peptidase
BKN48_RS17220	COG3212	peptidase
BKN48_RS17240	COG2239	Acts as a magnesium transporter
BKN48_RS17245	COG0789	Transcriptional regulator
BKN48_RS17260	COG1846	Transcriptional regulator
BKN48_RS17265	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKN48_RS17270	COG0726	polysaccharide deacetylase
BKN48_RS17275	COG1408	metallophosphoesterase
BKN48_RS17285	COG0463	Glycosyl transferase, family 2
BKN48_RS17290	COG1793	dna ligase
BKN48_RS17290	COG3285	dna ligase
BKN48_RS17295	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKN48_RS17300	COG3300	MHYT domain
BKN48_RS17300	COG5001	Diguanylate cyclase
BKN48_RS17305	COG0586	Pfam SNARE associated Golgi protein
BKN48_RS17310	COG0861	Integral membrane protein TerC family
BKN48_RS17315	COG1191	sigma factor activity
BKN48_RS17335	COG0501	Belongs to the peptidase M48B family
BKN48_RS17340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BKN48_RS17355	COG3594	Acyltransferase
BKN48_RS17360	COG5002	protein histidine kinase activity
BKN48_RS17365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKN48_RS17375	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BKN48_RS17380	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BKN48_RS17385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BKN48_RS17390	COG0436	Aminotransferase
BKN48_RS17395	COG1850	ribulose-bisphosphate carboxylase activity
BKN48_RS17400	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BKN48_RS17405	COG0235	Class ii aldolase
BKN48_RS17410	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BKN48_RS17415	COG3339	Conserved Protein
BKN48_RS17430	COG3852	Histidine kinase
BKN48_RS17435	COG1846	Transcriptional regulator
BKN48_RS17440	COG1360	Flagellar Motor Protein
BKN48_RS17445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BKN48_RS17450	COG0542	response to heat
BKN48_RS17455	COG3949	Membrane
BKN48_RS17460	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BKN48_RS17465	COG0720	synthase
BKN48_RS17470	COG0602	queuosine metabolic process
BKN48_RS17475	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BKN48_RS17480	COG1733	regulation of RNA biosynthetic process
BKN48_RS17485	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS17490	COG1388	LysM domain
BKN48_RS17490	COG4641	Protein conserved in bacteria
BKN48_RS17495	COG1388	LysM domain
BKN48_RS17500	COG3858	chitin binding
BKN48_RS17510	COG4873	Protein conserved in bacteria
BKN48_RS17525	COG3773	Cell wall hydrolase
BKN48_RS17530	COG2244	polysaccharide biosynthetic process
BKN48_RS17535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKN48_RS17540	COG2217	Heavy metal translocating P-type atpase
BKN48_RS17550	COG0006	proline dipeptidase activity
BKN48_RS17560	COG1609	Transcriptional regulator
BKN48_RS17565	COG3711	transcriptional antiterminator
BKN48_RS17570	COG2190	(PTS) system
BKN48_RS17570	COG1263	PTS System
BKN48_RS17570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKN48_RS17575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKN48_RS17580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BKN48_RS17590	COG1533	DNA photolyase activity
BKN48_RS17595	COG0456	acetyltransferase
BKN48_RS17600	COG0840	transmembrane signaling receptor activity
BKN48_RS17605	COG2084	Dehydrogenase
BKN48_RS17610	COG4257	antibiotic catabolic process
BKN48_RS17615	COG2340	Cysteine-rich secretory protein family
BKN48_RS17620	COG0768	penicillin binding
BKN48_RS17625	COG4191	Histidine kinase
BKN48_RS17630	COG0436	Aminotransferase
BKN48_RS17640	COG0835	chemotaxis
BKN48_RS17640	COG0784	Response regulator, receiver
BKN48_RS17650	COG2814	Major facilitator Superfamily
BKN48_RS17655	COG1376	ErfK ybiS ycfS ynhG family protein
BKN48_RS17660	COG1408	metallophosphoesterase
BKN48_RS17665	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS17670	COG2200	EAL domain
BKN48_RS17680	COG4703	Protein of unknown function (DUF1797)
BKN48_RS17685	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BKN48_RS17695	COG0517	IMP dehydrogenase activity
BKN48_RS17700	COG0583	DNA-binding transcription factor activity
BKN48_RS17705	COG0716	FMN binding
BKN48_RS17715	COG0716	FMN binding
BKN48_RS17720	COG2171	N-acyltransferase activity
BKN48_RS17725	COG1473	amidohydrolase
BKN48_RS17735	COG0668	transmembrane transport
BKN48_RS17740	COG0450	alkyl hydroperoxide reductase
BKN48_RS17745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKN48_RS17760	COG0746	molybdenum cofactor guanylyltransferase activity
BKN48_RS17765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKN48_RS17770	COG0303	'Molybdopterin
BKN48_RS17775	COG1763	Mo-molybdopterin cofactor biosynthetic process
BKN48_RS17780	COG0314	molybdopterin synthase activity
BKN48_RS17785	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BKN48_RS17790	COG1132	(ABC) transporter
BKN48_RS17795	COG1132	(ABC) transporter
BKN48_RS17805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKN48_RS17810	COG1136	(ABC) transporter
BKN48_RS17815	COG0577	efflux transmembrane transporter activity
BKN48_RS17820	COG1349	DNA-binding transcription factor activity
BKN48_RS17825	COG1105	Belongs to the carbohydrate kinase PfkB family
BKN48_RS17830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKN48_RS17830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKN48_RS17830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKN48_RS17835	COG0681	Belongs to the peptidase S26 family
BKN48_RS17845	COG0488	(ABC) transporter
BKN48_RS17850	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKN48_RS17855	COG2309	aminopeptidase activity
BKN48_RS17865	COG1077	Cell shape determining protein MreB Mrl
BKN48_RS17870	COG2002	toxin-antitoxin pair type II binding
BKN48_RS17875	COG3852	Histidine kinase
BKN48_RS17880	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BKN48_RS17880	COG2105	PFAM AIG2 family protein
BKN48_RS17885	COG0569	domain protein
BKN48_RS17890	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BKN48_RS17895	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BKN48_RS17900	COG5503	Protein of unknown function (DUF1447)
BKN48_RS17905	COG0561	phosphatase activity
BKN48_RS17910	COG0242	peptide deformylase activity
BKN48_RS17920	COG0497	DNA recombination
BKN48_RS17925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKN48_RS17930	COG0022	dehydrogenase e1 component
BKN48_RS17935	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKN48_RS17940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKN48_RS17945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKN48_RS17950	COG1982	Orn Lys Arg decarboxylase major
BKN48_RS17955	COG4476	Belongs to the UPF0223 family
BKN48_RS17960	COG4493	Belongs to the UPF0637 family
BKN48_RS17970	COG0483	inositol monophosphate 1-phosphatase activity
BKN48_RS17980	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BKN48_RS18000	COG1595	DNA-templated transcription, initiation
BKN48_RS18020	COG1217	gtp-binding protein TYPA
BKN48_RS18030	COG4896	Protein conserved in bacteria
BKN48_RS18040	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BKN48_RS18045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKN48_RS18050	COG2066	Belongs to the glutaminase family
BKN48_RS18055	COG4838	Belongs to the UPF0358 family
BKN48_RS18060	COG0772	Belongs to the SEDS family
BKN48_RS18065	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BKN48_RS18070	COG1612	heme a metabolic process
BKN48_RS18075	COG0109	protoheme IX farnesyltransferase activity
BKN48_RS18080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKN48_RS18080	COG2010	Cytochrome c
BKN48_RS18085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKN48_RS18090	COG1845	cytochrome c oxidase, subunit III
BKN48_RS18095	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BKN48_RS18100	COG3336	cytochrome c oxidase
BKN48_RS18110	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BKN48_RS18115	COG2340	Cysteine-rich secretory protein family
BKN48_RS18130	COG3679	Belongs to the UPF0342 family
BKN48_RS18135	COG4471	UPF0298 protein
BKN48_RS18140	COG0742	ribosomal rna small subunit methyltransferase
BKN48_RS18145	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BKN48_RS18150	COG3314	Sporulation integral membrane protein YlbJ
BKN48_RS18155	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKN48_RS18160	COG3480	Lon protease (S16) C-terminal proteolytic domain
BKN48_RS18165	COG1323	Belongs to the UPF0348 family
BKN48_RS18175	COG1399	metal-binding, possibly nucleic acid-binding protein
BKN48_RS18190	COG0454	-acetyltransferase
BKN48_RS18195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKN48_RS18200	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BKN48_RS18205	COG2001	Belongs to the MraZ family
BKN48_RS18210	COG0275	rRNA processing
BKN48_RS18215	COG4839	cell division protein FtsL
BKN48_RS18220	COG0768	penicillin binding
BKN48_RS18230	COG0768	penicillin binding
BKN48_RS18240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BKN48_RS18250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKN48_RS18255	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BKN48_RS18260	COG0772	Belongs to the SEDS family
BKN48_RS18265	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKN48_RS18270	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BKN48_RS18275	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BKN48_RS18280	COG3879	Bacterial protein of unknown function (DUF881)
BKN48_RS18285	COG3879	Bacterial protein of unknown function (DUF881)
BKN48_RS18290	COG3856	small basic protein
BKN48_RS18295	COG0849	cell division
BKN48_RS18300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BKN48_RS18305	COG4412	M6 family metalloprotease domain protein
BKN48_RS18305	COG1404	Belongs to the peptidase S8 family
BKN48_RS18315	COG1191	sigma factor activity
BKN48_RS18320	COG1191	sigma factor activity
BKN48_RS18325	COG1119	ATPase activity
BKN48_RS18330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKN48_RS18335	COG1873	PFAM PRC-barrel domain
BKN48_RS18340	COG1496	oxidoreductase activity
BKN48_RS18345	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BKN48_RS18350	COG1799	cell septum assembly
BKN48_RS18355	COG0762	integral membrane protein
BKN48_RS18360	COG2302	S4 RNA-binding domain
BKN48_RS18365	COG3599	regulation of cell shape
BKN48_RS18370	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BKN48_RS18375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BKN48_RS18380	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BKN48_RS18385	COG0564	pseudouridine synthase activity
BKN48_RS18390	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BKN48_RS18395	COG2233	PERMEase
BKN48_RS18400	COG0540	Belongs to the ATCase OTCase family
BKN48_RS18405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKN48_RS18410	COG0505	Belongs to the CarA family
BKN48_RS18415	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKN48_RS18420	COG0543	2 iron, 2 sulfur cluster binding
BKN48_RS18425	COG0167	dihydroorotate dehydrogenase activity
BKN48_RS18430	COG0284	orotidine-5'-phosphate decarboxylase activity
BKN48_RS18435	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BKN48_RS18440	COG0175	sulfate reduction
BKN48_RS18445	COG0306	phosphate transporter
BKN48_RS18450	COG2046	Belongs to the sulfate adenylyltransferase family
BKN48_RS18455	COG0529	Catalyzes the synthesis of activated sulfate
BKN48_RS18460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BKN48_RS18465	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BKN48_RS18470	COG1648	precorrin-2 dehydrogenase activity
BKN48_RS18475	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BKN48_RS18480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKN48_RS18485	COG1561	YicC-like family, N-terminal region
BKN48_RS18495	COG0194	GDP metabolic process
BKN48_RS18500	COG1758	RNA polymerase activity
BKN48_RS18505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BKN48_RS18510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BKN48_RS18515	COG0242	peptide deformylase activity
BKN48_RS18520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKN48_RS18525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKN48_RS18525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BKN48_RS18530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BKN48_RS18535	COG0631	protein serine/threonine phosphatase activity
BKN48_RS18540	COG2815	serine threonine protein kinase
BKN48_RS18540	COG0515	serine threonine protein kinase
BKN48_RS18545	COG1162	GTPase activity
BKN48_RS18550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BKN48_RS18555	COG1564	THIamine pyrophosphokinase
BKN48_RS18565	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BKN48_RS18570	COG1302	Protein conserved in bacteria
BKN48_RS18575	COG1461	Dihydroxyacetone kinase
BKN48_RS18580	COG1760	l-serine dehydratase
BKN48_RS18585	COG1760	l-serine dehydratase
BKN48_RS18590	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BKN48_RS18595	COG1349	DNA-binding transcription factor activity
BKN48_RS18595	COG2050	protein possibly involved in aromatic compounds catabolism
BKN48_RS18600	COG0416	fatty acid biosynthetic process
BKN48_RS18605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKN48_RS18610	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS18620	COG0571	ribonuclease III activity
BKN48_RS18625	COG1196	nuclear chromosome segregation
BKN48_RS18630	COG0552	protein localization to endoplasmic reticulum
BKN48_RS18640	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BKN48_RS18645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BKN48_RS18650	COG0228	four-way junction DNA binding
BKN48_RS18655	COG1837	Belongs to the UPF0109 family
BKN48_RS18665	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BKN48_RS18670	COG0336	Belongs to the RNA methyltransferase TrmD family
BKN48_RS18675	COG0335	large ribosomal subunit rRNA binding
BKN48_RS18680	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BKN48_RS18685	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKN48_RS18695	COG2257	FlhB HrpN YscU SpaS Family
BKN48_RS18700	COG0045	succinate-CoA ligase (ADP-forming) activity
BKN48_RS18705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BKN48_RS18710	COG0758	DNA mediated transformation
BKN48_RS18715	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKN48_RS18720	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BKN48_RS18725	COG4974	Belongs to the 'phage' integrase family
BKN48_RS18730	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BKN48_RS18735	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BKN48_RS18740	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BKN48_RS18745	COG1815	bacterial-type flagellum-dependent cell motility
BKN48_RS18750	COG1558	bacterial-type flagellum-dependent cell motility
BKN48_RS18755	COG1677	Flagellar hook-basal body complex protein FliE
BKN48_RS18760	COG1766	The M ring may be actively involved in energy transduction
BKN48_RS18765	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKN48_RS18770	COG1317	bacterial-type flagellum organization
BKN48_RS18775	COG1157	protein secretion by the type III secretion system
BKN48_RS18780	COG2882	bacterial-type flagellum organization
BKN48_RS18785	COG3334	PFAM MgtE intracellular
BKN48_RS18790	COG3144	bacterial-type flagellum assembly
BKN48_RS18795	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BKN48_RS18800	COG4786	Flagellar basal body rod
BKN48_RS18805	COG1582	Flagellar protein (FlbD)
BKN48_RS18810	COG1580	Controls the rotational direction of flagella during chemotaxis
BKN48_RS18815	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKN48_RS18820	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKN48_RS18820	COG1776	CheC inhibitor of MCP methylation
BKN48_RS18825	COG2201	protein-glutamate methylesterase activity
BKN48_RS18830	COG3190	flagellar
BKN48_RS18835	COG1338	Plays a role in the flagellum-specific transport system
BKN48_RS18840	COG1987	bacterial-type flagellum assembly
BKN48_RS18845	COG1684	flagellar biosynthetic protein fliR
BKN48_RS18850	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKN48_RS18855	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKN48_RS18860	COG1419	protein localization to endoplasmic reticulum
BKN48_RS18865	COG0455	bacterial-type flagellum organization
BKN48_RS18870	COG2201	protein-glutamate methylesterase activity
BKN48_RS18875	COG0643	Histidine kinase
BKN48_RS18875	COG2198	Histidine kinase
BKN48_RS18880	COG0835	chemotaxis
BKN48_RS18885	COG1776	CheC inhibitor of MCP methylation
BKN48_RS18890	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BKN48_RS18895	COG1191	sigma factor activity
BKN48_RS18905	COG0052	Belongs to the universal ribosomal protein uS2 family
BKN48_RS18910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BKN48_RS18915	COG0528	UMP kinase activity
BKN48_RS18920	COG0233	cytoplasmic translational termination
BKN48_RS18925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BKN48_RS18930	COG4589	Belongs to the CDS family
BKN48_RS18935	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BKN48_RS18940	COG0750	zinc metalloprotease
BKN48_RS18945	COG0442	prolyl-tRNA aminoacylation
BKN48_RS18950	COG2176	DNA-directed DNA polymerase activity
BKN48_RS18955	COG0779	Required for maturation of 30S ribosomal subunits
BKN48_RS18960	COG0195	Participates in both transcription termination and antitermination
BKN48_RS18965	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BKN48_RS18970	COG1358	cellular component organization or biogenesis
BKN48_RS18975	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BKN48_RS18980	COG1550	Protein conserved in bacteria
BKN48_RS18985	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BKN48_RS18990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BKN48_RS18995	COG0196	riboflavin kinase activity
BKN48_RS19000	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BKN48_RS19005	COG1185	polyribonucleotide nucleotidyltransferase activity
BKN48_RS19010	COG0726	polysaccharide deacetylase
BKN48_RS19015	COG0612	Peptidase, M16
BKN48_RS19020	COG1873	PFAM PRC-barrel domain
BKN48_RS19030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKN48_RS19035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BKN48_RS19040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BKN48_RS19045	COG0527	aspartate kinase activity
BKN48_RS19050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKN48_RS19055	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BKN48_RS19060	COG0740	serine-type endopeptidase activity
BKN48_RS19070	COG1674	ftsk spoiiie
BKN48_RS19070	COG4980	gas vesicle protein
BKN48_RS19075	COG2188	Transcriptional regulator
BKN48_RS19080	COG2814	Major facilitator Superfamily
BKN48_RS19085	COG0612	Peptidase, M16
BKN48_RS19090	COG0612	Peptidase, M16
BKN48_RS19095	COG0300	oxidoreductase activity
BKN48_RS19110	COG1426	Protein conserved in bacteria
BKN48_RS19115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BKN48_RS19120	COG1058	Belongs to the CinA family
BKN48_RS19120	COG1546	Belongs to the CinA family
BKN48_RS19125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BKN48_RS19130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKN48_RS19135	COG1418	mRNA catabolic process
BKN48_RS19140	COG1692	metallophosphoesterase
BKN48_RS19145	COG2359	stage V sporulation protein S
BKN48_RS19150	COG1063	alcohol dehydrogenase
BKN48_RS19155	COG0156	8-amino-7-oxononanoate synthase activity
BKN48_RS19160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKN48_RS19165	COG4550	Control of competence regulator ComK, YlbF/YmcA
BKN48_RS19175	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BKN48_RS19180	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BKN48_RS19200	COG3226	Transcriptional regulator
BKN48_RS19205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN48_RS19215	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKN48_RS19220	COG3321	synthase
BKN48_RS19225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKN48_RS19225	COG2070	2-Nitropropane dioxygenase
BKN48_RS19230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKN48_RS19235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKN48_RS19240	COG3425	synthase
BKN48_RS19245	COG1024	Enoyl-CoA hydratase
BKN48_RS19250	COG1024	Enoyl-CoA hydratase
BKN48_RS19255	COG3321	synthase
BKN48_RS19255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN48_RS19255	COG0318	PFAM AMP-dependent synthetase and ligase
BKN48_RS19255	COG0300	oxidoreductase activity
BKN48_RS19255	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS19260	COG0300	oxidoreductase activity
BKN48_RS19260	COG4221	oxidoreductase activity
BKN48_RS19260	COG3321	synthase
BKN48_RS19260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKN48_RS19265	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS19265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN48_RS19265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKN48_RS19265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKN48_RS19265	COG3321	synthase
BKN48_RS19270	COG4221	oxidoreductase activity
BKN48_RS19270	COG3321	synthase
BKN48_RS19270	COG1028	Short-chain dehydrogenase reductase Sdr
BKN48_RS19270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN48_RS19275	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BKN48_RS19275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BKN48_RS19275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKN48_RS19275	COG3321	synthase
BKN48_RS19280	COG2124	cytochrome p450
BKN48_RS19290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN48_RS19295	COG1404	Belongs to the peptidase S8 family
BKN48_RS19305	COG4195	phage-related replication protein
BKN48_RS19310	COG1764	response to oxidative stress
BKN48_RS19315	COG2076	Multidrug Resistance protein
BKN48_RS19320	COG2076	Multidrug Resistance protein
BKN48_RS19335	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BKN48_RS19340	COG1923	regulation of RNA biosynthetic process
BKN48_RS19355	COG1780	Probably involved in ribonucleotide reductase function
BKN48_RS19360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKN48_RS19365	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKN48_RS19370	COG4112	unkown
BKN48_RS19375	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKN48_RS19380	COG0464	growth
BKN48_RS19390	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKN48_RS19395	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BKN48_RS19400	COG0789	Transcriptional regulator
BKN48_RS19405	COG0174	glutamine synthetase
BKN48_RS19455	COG4282	regulation of fungal-type cell wall biogenesis
BKN48_RS19460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN48_RS19485	COG0135	phosphoribosylanthranilate isomerase activity
BKN48_RS19490	COG2211	Major facilitator Superfamily
BKN48_RS19495	COG3507	Belongs to the glycosyl hydrolase 43 family
BKN48_RS19500	COG1940	carbohydrate kinase activity
BKN48_RS19505	COG2115	Belongs to the xylose isomerase family
BKN48_RS19510	COG1070	Carbohydrate kinase
BKN48_RS19515	COG1525	nuclease
BKN48_RS19520	COG2814	Major facilitator Superfamily
BKN48_RS19525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BKN48_RS19535	COG0756	dUTP diphosphatase activity
BKN48_RS19570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKN48_RS19580	COG3832	glyoxalase III activity
BKN48_RS19595	COG0697	spore germination
BKN48_RS19600	COG0531	amino acid
BKN48_RS19630	COG4195	phage-related replication protein
BKN48_RS19640	COG0346	lactoylglutathione lyase activity
BKN48_RS19650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKN48_RS19655	COG1388	LysM domain
BKN48_RS19660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BKN48_RS19665	COG4224	UPF0291 protein
BKN48_RS19670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BKN48_RS19680	COG3763	UPF0154 protein
BKN48_RS19690	COG0785	Cytochrome C biogenesis protein
BKN48_RS19695	COG2201	protein-glutamate methylesterase activity
BKN48_RS19700	COG4846	Membrane protein involved in cytochrome C biogenesis
BKN48_RS19710	COG0071	Belongs to the small heat shock protein (HSP20) family
BKN48_RS19725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BKN48_RS19730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKN48_RS19750	COG0824	Thioesterase
BKN48_RS19760	COG4841	protein insertion into membrane
BKN48_RS19765	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BKN48_RS19770	COG1832	CoA-binding protein
BKN48_RS19775	COG0187	DNA topoisomerase II activity
BKN48_RS19780	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKN48_RS19795	COG1115	amino acid carrier protein
BKN48_RS19800	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BKN48_RS19810	COG5520	Belongs to the glycosyl hydrolase 30 family
BKN48_RS19815	COG3507	Belongs to the glycosyl hydrolase 43 family
BKN48_RS19820	COG2246	polysaccharide biosynthetic process
BKN48_RS19825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKN48_RS19830	COG0586	Pfam SNARE associated Golgi protein
BKN48_RS19835	COG2404	hydrolase activity, acting on ester bonds
BKN48_RS19840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKN48_RS19845	COG1024	Enoyl-CoA hydratase
BKN48_RS19850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKN48_RS19855	COG0511	ligase activity, forming carbon-carbon bonds
BKN48_RS19860	COG0439	Biotin carboxylase
BKN48_RS19865	COG0318	PFAM AMP-dependent synthetase and ligase
BKN48_RS19870	COG1960	acyl-CoA dehydrogenase activity
BKN48_RS19885	COG1649	PFAM Uncharacterised BCR, COG1649
BKN48_RS19895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN48_RS19895	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BKN48_RS19900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN48_RS19905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN48_RS19910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN48_RS19915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BKN48_RS19920	COG2027	D-alanyl-D-alanine carboxypeptidase
BKN48_RS19925	COG2017	converts alpha-aldose to the beta-anomer
BKN48_RS19930	COG0534	Mate efflux family protein
BKN48_RS19945	COG0582	viral genome integration into host DNA
BKN48_RS19950	COG0166	Belongs to the GPI family
BKN48_RS19955	COG0405	Gamma-glutamyltransferase
BKN48_RS19960	COG0583	DNA-binding transcription factor activity
BKN48_RS19965	COG0604	alcohol dehydrogenase
BKN48_RS19970	COG0493	'glutamate synthase
BKN48_RS19975	COG0070	glutamate synthase
BKN48_RS19975	COG0067	glutamate synthase
BKN48_RS19975	COG0069	glutamate synthase activity
BKN48_RS19980	COG0583	DNA-binding transcription factor activity
BKN48_RS19985	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BKN48_RS19990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BKN48_RS20000	COG0300	oxidoreductase activity
BKN48_RS20005	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BKN48_RS20015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKN48_RS20020	COG2814	Major facilitator Superfamily
BKN48_RS20025	COG1070	Carbohydrate kinase
BKN48_RS20030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKN48_RS20035	COG0243	molybdopterin cofactor binding
BKN48_RS20060	COG0840	transmembrane signaling receptor activity
BKN48_RS20060	COG5278	phosphoserine phosphatase activity
BKN48_RS20065	COG2368	4-hydroxyphenylacetate
BKN48_RS20070	COG4305	rare lipoprotein A
BKN48_RS20075	COG3619	membrane
BKN48_RS20080	COG3866	Pectate lyase
BKN48_RS20085	COG2135	peptidase activity
BKN48_RS20095	COG2140	Oxalate decarboxylase
BKN48_RS20105	COG0456	acetyltransferase
BKN48_RS20120	COG2720	vancomycin resistance protein
BKN48_RS20130	COG3655	Transcriptional regulator
BKN48_RS20135	COG3739	integral membrane protein
BKN48_RS20140	COG0583	DNA-binding transcription factor activity
BKN48_RS20145	COG0697	spore germination
BKN48_RS20155	COG0693	protein deglycase activity
BKN48_RS20160	COG2367	Beta-lactamase
BKN48_RS20180	COG0574	Belongs to the PEP-utilizing enzyme family
BKN48_RS20180	COG3848	Pyruvate phosphate dikinase
BKN48_RS20185	COG0726	polysaccharide deacetylase
BKN48_RS20195	COG2314	TM2 domain
BKN48_RS20220	COG1396	sequence-specific DNA binding
BKN48_RS20225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKN48_RS20235	COG1620	l-lactate permease
BKN48_RS20255	COG0463	Glycosyl transferase, family 2
BKN48_RS20310	COG4282	regulation of fungal-type cell wall biogenesis
BKN48_RS20315	COG1231	oxidoreductase activity
BKN48_RS20320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKN48_RS20325	COG2207	Transcriptional regulator
BKN48_RS20325	COG0662	Cupin 2, conserved barrel domain protein
BKN48_RS20330	COG0456	acetyltransferase
BKN48_RS20335	COG1309	transcriptional regulator
BKN48_RS20340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKN48_RS20345	COG3708	Transcriptional regulator
BKN48_RS20350	COG2378	regulation of single-species biofilm formation
BKN48_RS20360	COG0640	Transcriptional regulator
BKN48_RS20365	COG0741	lytic transglycosylase activity
BKN48_RS20370	COG2322	membrane
BKN48_RS20385	COG1619	proteins homologs of microcin C7 resistance protein MccF
BKN48_RS20390	COG3239	Fatty acid desaturase
BKN48_RS20395	COG4585	Histidine kinase
BKN48_RS20400	COG2197	response regulator
BKN48_RS20405	COG1388	LysM domain
BKN48_RS20405	COG3584	3D domain protein
BKN48_RS20410	COG0514	ATP-dependent DNA helicase (RecQ)
BKN48_RS20425	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BKN48_RS20430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BKN48_RS20445	COG0071	Belongs to the small heat shock protein (HSP20) family
BKN48_RS20470	COG1012	belongs to the aldehyde dehydrogenase family
BKN48_RS20475	COG1657	PFAM Prenyltransferase squalene oxidase
BKN48_RS20480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BKN48_RS20485	COG0733	neurotransmitter:sodium symporter activity
BKN48_RS20490	COG0385	Bile acid
BKN48_RS20495	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKN48_RS20500	COG0567	Dehydrogenase, E1 component
BKN48_RS20505	COG4548	von Willebrand factor, type A
BKN48_RS20510	COG0714	Associated with various cellular activities
BKN48_RS20515	COG2032	superoxide dismutase activity
BKN48_RS20520	COG1388	LysM domain
BKN48_RS20520	COG0791	NLP P60 protein