locus-tag	class	description
J9312_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J9312_RS00010	COG0592	DNA-directed DNA polymerase activity
J9312_RS00015	COG2501	S4 domain
J9312_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J9312_RS00030	COG0187	DNA topoisomerase II activity
J9312_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J9312_RS00070	COG0516	GMP reductase activity
J9312_RS00070	COG0517	IMP dehydrogenase activity
J9312_RS00075	COG1686	Belongs to the peptidase S11 family
J9312_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
J9312_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
J9312_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J9312_RS00100	COG1428	Deoxynucleoside kinase
J9312_RS00105	COG1428	Deoxynucleoside kinase
J9312_RS00110	COG1388	LysM domain
J9312_RS00110	COG3858	chitin binding
J9312_RS00115	COG1335	isochorismatase
J9312_RS00120	COG0590	tRNA wobble adenosine to inosine editing
J9312_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J9312_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J9312_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J9312_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
J9312_RS00190	COG3853	Toxic anion resistance protein (TelA)
J9312_RS00195	COG1982	Orn Lys Arg decarboxylase major
J9312_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J9312_RS00205	COG3870	Protein conserved in bacteria
J9312_RS00210	COG1728	Protein conserved in bacteria
J9312_RS00215	COG0470	DNA polymerase III
J9312_RS00220	COG1774	PSP1 C-terminal conserved region
J9312_RS00225	COG4467	Involved in initiation control of chromosome replication
J9312_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J9312_RS00235	COG2827	Endonuclease containing a URI domain
J9312_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J9312_RS00245	COG3328	transposase activity
J9312_RS00250	COG2002	toxin-antitoxin pair type II binding
J9312_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J9312_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J9312_RS00260	COG0084	hydrolase, TatD family'
J9312_RS00265	COG3584	3D domain protein
J9312_RS00265	COG3583	domain protein
J9312_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J9312_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J9312_RS00285	COG4466	Protein conserved in bacteria
J9312_RS00295	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J9312_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J9312_RS00305	COG0251	oxidation-reduction process
J9312_RS00310	COG2088	sporulation resulting in formation of a cellular spore
J9312_RS00315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J9312_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J9312_RS00325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J9312_RS00330	COG0193	aminoacyl-tRNA hydrolase activity
J9312_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J9312_RS00345	COG2002	toxin-antitoxin pair type II binding
J9312_RS00350	COG2244	polysaccharide biosynthetic process
J9312_RS00355	COG3956	TIGRFAM MazG family protein
J9312_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J9312_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J9312_RS00380	COG1098	S1 RNA binding domain
J9312_RS00395	COG2208	phosphoserine phosphatase activity
J9312_RS00400	COG2304	oxidoreductase activity
J9312_RS00405	COG0515	serine threonine protein kinase
J9312_RS00410	COG0037	tRNA processing
J9312_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J9312_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J9312_RS00425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J9312_RS00430	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J9312_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J9312_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J9312_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J9312_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
J9312_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J9312_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J9312_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J9312_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J9312_RS00475	COG1396	sequence-specific DNA binding
J9312_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J9312_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J9312_RS00565	COG4463	regulation of RNA biosynthetic process
J9312_RS00570	COG3880	PFAM UvrB UvrC protein
J9312_RS00575	COG3869	Catalyzes the specific phosphorylation of arginine residues in
J9312_RS00580	COG0542	response to heat
J9312_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J9312_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
J9312_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
J9312_RS00600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J9312_RS00605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J9312_RS00610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J9312_RS00615	COG1045	serine acetyltransferase
J9312_RS00620	COG0215	cysteine-tRNA ligase activity
J9312_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
J9312_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J9312_RS00635	COG3688	RNA-binding protein containing a PIN domain
J9312_RS00640	COG1595	DNA-templated transcription, initiation
J9312_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J9312_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
J9312_RS00665	COG0081	regulation of translation
J9312_RS00670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J9312_RS00680	COG2813	Specifically methylates the guanine in position
J9312_RS00685	COG0085	RNA polymerase activity
J9312_RS00690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J9312_RS00695	COG1358	cellular component organization or biogenesis
J9312_RS00700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J9312_RS00705	COG0049	tRNA binding
J9312_RS00710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J9312_RS00715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J9312_RS00720	COG0596	Alpha beta hydrolase
J9312_RS00730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J9312_RS00735	COG0088	Forms part of the polypeptide exit tunnel
J9312_RS00745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J9312_RS00760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J9312_RS00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J9312_RS00775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J9312_RS00780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J9312_RS00790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J9312_RS00800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J9312_RS00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J9312_RS00810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J9312_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J9312_RS00825	COG0200	Binds to the 23S rRNA
J9312_RS00830	COG0201	protein transport
J9312_RS00835	COG0563	adenylate kinase activity
J9312_RS00840	COG0024	Methionine aminopeptidase
J9312_RS00845	COG2163	COG2163 Ribosomal protein L14E L6E L27E
J9312_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J9312_RS00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J9312_RS00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J9312_RS00870	COG0202	RNA polymerase activity
J9312_RS00875	COG0203	ribosomal protein L17
J9312_RS00880	COG1122	ATPase activity
J9312_RS00885	COG1122	ATPase activity
J9312_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J9312_RS00895	COG0101	tRNA pseudouridine synthase activity
J9312_RS00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J9312_RS00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J9312_RS00910	COG2226	methyltransferase
J9312_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
J9312_RS00925	COG0489	protein tyrosine kinase activity
J9312_RS00935	COG2194	sulfuric ester hydrolase activity
J9312_RS00940	COG0726	polysaccharide deacetylase
J9312_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
J9312_RS01030	COG0385	Bile acid
J9312_RS01035	COG2819	hydrolase of the alpha beta superfamily
J9312_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J9312_RS01055	COG2207	Transcriptional regulator
J9312_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J9312_RS01060	COG3876	Protein conserved in bacteria
J9312_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
J9312_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J9312_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_RS01075	COG1263	PTS System
J9312_RS01080	COG1737	Transcriptional regulator
J9312_RS01085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J9312_RS01090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_RS01095	COG1683	Conserved Protein
J9312_RS01125	COG1595	DNA-templated transcription, initiation
J9312_RS01130	COG5662	AntiSigma factor
J9312_RS01135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J9312_RS01140	COG4856	YbbR-like protein
J9312_RS01145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J9312_RS01150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J9312_RS01160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J9312_RS01165	COG2169	Transcriptional regulator
J9312_RS01170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J9312_RS01175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J9312_RS01180	COG3002	Belongs to the UPF0753 family
J9312_RS01185	COG0288	reversible hydration of carbon dioxide
J9312_RS01195	COG5609	conserved protein (DUF2294)
J9312_RS01200	COG0640	Transcriptional regulator
J9312_RS01205	COG2814	Major facilitator Superfamily
J9312_RS01220	COG0596	Alpha beta hydrolase
J9312_RS01225	COG0745	RESPONSE REGULATOR receiver
J9312_RS01230	COG0642	Histidine kinase
J9312_RS01240	COG0515	serine threonine protein kinase
J9312_RS01255	COG1113	amino acid transport
J9312_RS01270	COG2602	Beta-lactamase
J9312_RS01275	COG2124	cytochrome p450
J9312_RS01285	COG0531	amino acid
J9312_RS01290	COG0584	glycerophosphoryl diester phosphodiesterase
J9312_RS01295	COG2271	Major facilitator Superfamily
J9312_RS01305	COG1846	Transcriptional regulator
J9312_RS01305	COG0456	acetyltransferase
J9312_RS01320	COG3409	Peptidoglycan-binding domain 1 protein
J9312_RS01325	COG0697	spore germination
J9312_RS01330	COG1917	Cupin 2, conserved barrel domain protein
J9312_RS01330	COG2207	Transcriptional regulator
J9312_RS01355	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J9312_RS01360	COG3591	Belongs to the peptidase S1B family
J9312_RS01370	COG0596	Alpha beta hydrolase
J9312_RS01375	COG1183	phosphatidylcholine synthase activity
J9312_RS01380	COG0586	Pfam SNARE associated Golgi protein
J9312_RS01385	COG0688	phosphatidylethanolamine metabolic process
J9312_RS01395	COG2312	Erythromycin esterase
J9312_RS01400	COG2207	Transcriptional regulator
J9312_RS01405	COG1054	Belongs to the UPF0176 family
J9312_RS01410	COG1301	dicarboxylic acid transport
J9312_RS01415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_RS01415	COG2190	(PTS) system
J9312_RS01415	COG1263	PTS System
J9312_RS01420	COG0363	glucosamine-6-phosphate deaminase activity
J9312_RS01425	COG2188	Transcriptional regulator
J9312_RS01435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J9312_RS01440	COG0833	amino acid
J9312_RS01445	COG2040	homocysteine
J9312_RS01455	COG2066	Belongs to the glutaminase family
J9312_RS01460	COG4191	Histidine kinase
J9312_RS01465	COG0784	Response regulator, receiver
J9312_RS01470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J9312_RS01475	COG1012	belongs to the aldehyde dehydrogenase family
J9312_RS01480	COG2271	Major facilitator Superfamily
J9312_RS01485	COG4948	Mandelate Racemase Muconate Lactonizing
J9312_RS01490	COG2186	Transcriptional regulator
J9312_RS01495	COG2721	sulfolactate sulfo-lyase activity
J9312_RS01500	COG3173	Aminoglycoside phosphotransferase
J9312_RS01510	COG0697	spore germination
J9312_RS01515	COG0745	RESPONSE REGULATOR receiver
J9312_RS01520	COG2205	protein histidine kinase activity
J9312_RS01525	COG1131	(ABC) transporter
J9312_RS01545	COG3773	Cell wall hydrolase
J9312_RS01550	COG2304	oxidoreductase activity
J9312_RS01560	COG3540	Alkaline phosphatase
J9312_RS01565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J9312_RS01570	COG0805	protein transport
J9312_RS01575	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
J9312_RS01580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J9312_RS01585	COG0477	Major facilitator Superfamily
J9312_RS01590	COG1309	transcriptional regulator
J9312_RS01595	COG0252	asparaginase activity
J9312_RS01600	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J9312_RS01605	COG1714	RDD family
J9312_RS01610	COG3012	SEC-C Motif Domain Protein
J9312_RS01610	COG1405	negative regulation of cell septum assembly
J9312_RS01620	COG3279	Response regulator of the LytR AlgR family
J9312_RS01630	COG1668	transmembrane transport
J9312_RS01635	COG0667	Aldo Keto reductase
J9312_RS01650	COG1595	DNA-templated transcription, initiation
J9312_RS01655	COG1595	DNA-templated transcription, initiation
J9312_RS01660	COG1876	peptidase activity
J9312_RS01670	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS01680	COG0803	Belongs to the bacterial solute-binding protein 9 family
J9312_RS01685	COG1121	(ABC) transporter
J9312_RS01690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J9312_RS01695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J9312_RS01700	COG2310	stress, protein
J9312_RS01705	COG2310	stress, protein
J9312_RS01710	COG2310	stress, protein
J9312_RS01715	COG0861	Integral membrane protein TerC family
J9312_RS01725	COG3853	Toxic anion resistance protein (TelA)
J9312_RS01730	COG0477	Major facilitator Superfamily
J9312_RS01735	COG2814	Major facilitator Superfamily
J9312_RS01740	COG0640	Transcriptional regulator
J9312_RS01745	COG4175	Glycine betaine
J9312_RS01745	COG0517	IMP dehydrogenase activity
J9312_RS01750	COG4176	ABC-type proline glycine betaine transport system permease component
J9312_RS01755	COG2113	Glycine betaine
J9312_RS01760	COG1473	amidohydrolase
J9312_RS01765	COG1288	antiporter activity
J9312_RS01780	COG0039	L-malate dehydrogenase activity
J9312_RS01795	COG3403	YqcI/YcgG family
J9312_RS01810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J9312_RS01815	COG1660	Displays ATPase and GTPase activities
J9312_RS01820	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J9312_RS01825	COG2226	methyltransferase
J9312_RS01830	COG0583	DNA-binding transcription factor activity
J9312_RS01835	COG3458	cephalosporin-C deacetylase activity
J9312_RS01840	COG3541	Predicted nucleotidyltransferase
J9312_RS01845	COG0506	proline dehydrogenase activity
J9312_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
J9312_RS01855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J9312_RS01860	COG2508	Transcriptional regulator
J9312_RS01865	COG3689	TIGRFAM TIGR03943 family protein
J9312_RS01870	COG0701	Predicted permease
J9312_RS01875	COG2267	carboxylic ester hydrolase activity
J9312_RS01880	COG0492	ferredoxin-NADP+ reductase activity
J9312_RS01885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J9312_RS01885	COG1587	Uroporphyrinogen-III synthase
J9312_RS01890	COG2146	nitrite reductase [NAD(P)H] activity
J9312_RS01895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J9312_RS01900	COG0243	molybdopterin cofactor binding
J9312_RS01905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J9312_RS01910	COG2223	nitrite transmembrane transporter activity
J9312_RS01920	COG1376	ErfK ybiS ycfS ynhG family protein
J9312_RS01935	COG0765	amino acid transport
J9312_RS01940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J9312_RS01950	COG1714	RDD family
J9312_RS01960	COG1846	Transcriptional regulator
J9312_RS01975	COG2723	6-phospho-beta-galactosidase activity
J9312_RS01985	COG3209	COG3209 Rhs family protein
J9312_RS01995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J9312_RS02000	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
J9312_RS02005	COG1733	regulation of RNA biosynthetic process
J9312_RS02010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J9312_RS02030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J9312_RS02035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J9312_RS02040	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
J9312_RS02045	COG2814	Major facilitator Superfamily
J9312_RS02055	COG0697	spore germination
J9312_RS02060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_RS02070	COG2364	Membrane
J9312_RS02075	COG1126	abc transporter atp-binding protein
J9312_RS02080	COG0765	amino acid transport
J9312_RS02085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J9312_RS02090	COG0583	DNA-binding transcription factor activity
J9312_RS02095	COG0163	prenyltransferase activity
J9312_RS02100	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J9312_RS02115	COG0596	Alpha beta hydrolase
J9312_RS02120	COG3104	oligopeptide transport
J9312_RS02125	COG5434	Belongs to the glycosyl hydrolase 28 family
J9312_RS02135	COG0697	spore germination
J9312_RS02145	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J9312_RS02150	COG1136	(ABC) transporter
J9312_RS02155	COG0577	efflux transmembrane transporter activity
J9312_RS02160	COG0745	RESPONSE REGULATOR receiver
J9312_RS02165	COG5002	protein histidine kinase activity
J9312_RS02165	COG3850	Histidine kinase
J9312_RS02170	COG0457	Tetratricopeptide repeat
J9312_RS02190	COG0527	aspartate kinase activity
J9312_RS02195	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_RS02200	COG4605	iron ion homeostasis
J9312_RS02205	COG4604	ABC transporter, ATP-binding protein
J9312_RS02210	COG4607	ABC-type enterochelin transport system periplasmic component
J9312_RS02220	COG2814	Major facilitator Superfamily
J9312_RS02225	COG1309	transcriptional regulator
J9312_RS02230	COG0778	Nitroreductase
J9312_RS02235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J9312_RS02240	COG0640	Transcriptional regulator
J9312_RS02245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_RS02250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J9312_RS02255	COG1012	belongs to the aldehyde dehydrogenase family
J9312_RS02260	COG4975	Glucose uptake
J9312_RS02265	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS02270	COG4549	nuclear export factor GLE1
J9312_RS02275	COG2372	response to copper ion
J9312_RS02275	COG1276	copper resistance
J9312_RS02280	COG1349	DNA-binding transcription factor activity
J9312_RS02290	COG2213	PTS system mannitol-specific
J9312_RS02295	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_RS02300	COG0246	Mannitol dehydrogenase
J9312_RS02305	COG0473	3-isopropylmalate dehydrogenase activity
J9312_RS02310	COG0681	Belongs to the peptidase S26 family
J9312_RS02320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J9312_RS02330	COG0561	phosphatase activity
J9312_RS02335	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J9312_RS02340	COG1914	H( )-stimulated, divalent metal cation uptake system
J9312_RS02345	COG4336	lyase activity
J9312_RS02350	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J9312_RS02355	COG1984	allophanate hydrolase subunit 2
J9312_RS02360	COG1414	Transcriptional regulator
J9312_RS02365	COG2755	lipolytic protein G-D-S-L family
J9312_RS02375	COG2329	Antibiotic biosynthesis monooxygenase
J9312_RS02380	COG0768	penicillin binding
J9312_RS02385	COG4989	oxidoreductase activity
J9312_RS02390	COG3711	transcriptional antiterminator
J9312_RS02395	COG0318	PFAM AMP-dependent synthetase and ligase
J9312_RS02400	COG2226	methyltransferase
J9312_RS02405	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS02410	COG1917	Cupin 2, conserved barrel domain protein
J9312_RS02415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_RS02420	COG3871	stress protein (general stress protein 26)
J9312_RS02430	COG2814	Major facilitator Superfamily
J9312_RS02435	COG1522	sequence-specific DNA binding
J9312_RS02440	COG0551	DNA topoisomerase type I activity
J9312_RS02440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J9312_RS02445	COG0494	nUDIX hydrolase
J9312_RS02450	COG0028	Belongs to the TPP enzyme family
J9312_RS02475	COG1914	H( )-stimulated, divalent metal cation uptake system
J9312_RS02480	COG2261	transglycosylase associated protein
J9312_RS02485	COG4876	unkown
J9312_RS02490	COG2217	Heavy metal translocating P-type atpase
J9312_RS02495	COG3729	General stress protein
J9312_RS02500	COG0662	Cupin 2, conserved barrel domain protein
J9312_RS02505	COG2329	Antibiotic biosynthesis monooxygenase
J9312_RS02510	COG3546	catalase activity
J9312_RS02515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J9312_RS02520	COG3290	protein histidine kinase activity
J9312_RS02525	COG4565	transcriptional regulatory protein
J9312_RS02530	COG1301	dicarboxylic acid transport
J9312_RS02535	COG0628	permease
J9312_RS02540	COG1131	(ABC) transporter
J9312_RS02545	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J9312_RS02555	COG1960	acyl-CoA dehydrogenase activity
J9312_RS02570	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J9312_RS02575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_RS02580	COG1181	Belongs to the D-alanine--D-alanine ligase family
J9312_RS02585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J9312_RS02590	COG0513	Belongs to the DEAD box helicase family
J9312_RS02595	COG3402	PFAM membrane-flanked domain
J9312_RS02600	COG3428	Bacterial PH domain
J9312_RS02605	COG0705	Rhomboid family
J9312_RS02610	COG0736	holo-[acyl-carrier-protein] synthase activity
J9312_RS02615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J9312_RS02620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J9312_RS02625	COG0864	Transcriptional regulator
J9312_RS02630	COG2337	Toxic component of a toxin-antitoxin (TA) module
J9312_RS02635	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_RS02640	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_RS02645	COG2172	sigma factor antagonist activity
J9312_RS02650	COG2208	phosphoserine phosphatase activity
J9312_RS02655	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_RS02660	COG2172	sigma factor antagonist activity
J9312_RS02665	COG1191	sigma factor activity
J9312_RS02670	COG2208	phosphoserine phosphatase activity
J9312_RS02685	COG1673	EVE domain
J9312_RS02690	COG1846	Transcriptional regulator
J9312_RS02695	COG2183	response to ionizing radiation
J9312_RS02705	COG3091	SprT-like family
J9312_RS02745	COG0582	viral genome integration into host DNA
J9312_RS02750	COG2856	Zn peptidase
J9312_RS02755	COG1396	sequence-specific DNA binding
J9312_RS02785	COG1674	ftsk spoiiie
J9312_RS02790	COG2946	Replication initiation factor
J9312_RS02825	COG0433	COG0433 Predicted ATPase
J9312_RS02835	COG5644	endopeptidase inhibitor activity
J9312_RS02840	COG0741	lytic transglycosylase activity
J9312_RS02840	COG0791	NLP P60 protein
J9312_RS02855	COG0457	Tetratricopeptide repeat
J9312_RS02870	COG1401	restriction endodeoxyribonuclease activity
J9312_RS02875	COG1802	Transcriptional regulator
J9312_RS02885	COG5444	nuclease activity
J9312_RS02905	COG1476	TRANSCRIPTIONal
J9312_RS02930	COG0693	protein deglycase activity
J9312_RS02935	COG1278	Cold shock
J9312_RS02940	COG1329	Transcriptional regulator
J9312_RS02945	COG0697	spore germination
J9312_RS02950	COG1917	Cupin 2, conserved barrel domain protein
J9312_RS02950	COG2207	Transcriptional regulator
J9312_RS02955	COG0697	spore germination
J9312_RS02960	COG2207	Transcriptional regulator
J9312_RS02960	COG3708	Transcriptional regulator
J9312_RS02965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_RS02980	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
J9312_RS02995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_RS03000	COG1309	transcriptional regulator
J9312_RS03005	COG0697	spore germination
J9312_RS03010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_RS03015	COG2030	dehydratase
J9312_RS03020	COG3545	Serine hydrolase
J9312_RS03025	COG1733	regulation of RNA biosynthetic process
J9312_RS03030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_RS03035	COG0640	Transcriptional regulator
J9312_RS03040	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J9312_RS03050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_RS03055	COG0697	spore germination
J9312_RS03060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_RS03065	COG0076	glutamate decarboxylase activity
J9312_RS03070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J9312_RS03075	COG0640	Transcriptional regulator
J9312_RS03080	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J9312_RS03095	COG4585	Histidine kinase
J9312_RS03100	COG2197	response regulator
J9312_RS03105	COG2409	Drug exporters of the RND superfamily
J9312_RS03110	COG0596	Alpha beta hydrolase
J9312_RS03115	COG1811	Na channel or pump
J9312_RS03120	COG0789	Transcriptional regulator
J9312_RS03120	COG4978	Transcriptional regulator
J9312_RS03125	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J9312_RS03130	COG0778	Nitroreductase
J9312_RS03135	COG0346	lactoylglutathione lyase activity
J9312_RS03140	COG2259	Doxx family
J9312_RS03145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_RS03165	COG2323	membrane
J9312_RS03170	COG2323	membrane
J9312_RS03175	COG0071	Belongs to the small heat shock protein (HSP20) family
J9312_RS03190	COG1309	transcriptional regulator
J9312_RS03200	COG0456	acetyltransferase
J9312_RS03205	COG0488	(ABC) transporter
J9312_RS03210	COG1113	amino acid transport
J9312_RS03215	COG2318	DinB family
J9312_RS03220	COG1846	Transcriptional regulator
J9312_RS03225	COG2409	Drug exporters of the RND superfamily
J9312_RS03225	COG1033	growth of symbiont in host cell
J9312_RS03230	COG0778	Nitroreductase
J9312_RS03235	COG1846	Transcriptional regulator
J9312_RS03240	COG2814	Major facilitator Superfamily
J9312_RS03245	COG0730	response to heat
J9312_RS03250	COG1802	Transcriptional regulator
J9312_RS03255	COG1388	LysM domain
J9312_RS03255	COG3858	chitin binding
J9312_RS03260	COG1819	glycosyl
J9312_RS03270	COG1785	Belongs to the alkaline phosphatase family
J9312_RS03275	COG5646	InterPro IPR014922
J9312_RS03285	COG0454	-acetyltransferase
J9312_RS03290	COG1078	dGTPase activity
J9312_RS03295	COG1388	LysM domain
J9312_RS03300	COG2814	Major facilitator Superfamily
J9312_RS03305	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J9312_RS03320	COG2723	6-phospho-beta-galactosidase activity
J9312_RS03325	COG2188	Transcriptional regulator
J9312_RS03330	COG1940	carbohydrate kinase activity
J9312_RS03335	COG1482	cell wall glycoprotein biosynthetic process
J9312_RS03340	COG4124	Belongs to the glycosyl hydrolase 26 family
J9312_RS03385	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J9312_RS03390	COG0802	atpase or kinase
J9312_RS03395	COG1214	PFAM Peptidase M22, glycoprotease
J9312_RS03400	COG0456	acetyltransferase
J9312_RS03405	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J9312_RS03410	COG0488	(ABC) transporter
J9312_RS03415	COG0315	cyclic pyranopterin monophosphate synthase activity
J9312_RS03420	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
J9312_RS03425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J9312_RS03430	COG0805	protein transport
J9312_RS03440	COG1266	CAAX protease self-immunity
J9312_RS03450	COG0459	protein refolding
J9312_RS03465	COG0457	Tetratricopeptide repeat
J9312_RS03470	COG1063	alcohol dehydrogenase
J9312_RS03475	COG2211	Major facilitator Superfamily
J9312_RS03480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J9312_RS03485	COG1842	Phage shock protein A
J9312_RS03490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J9312_RS03495	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
J9312_RS03500	COG4260	virion core protein, lumpy skin disease virus
J9312_RS03510	COG2814	Major facilitator Superfamily
J9312_RS03515	COG1063	alcohol dehydrogenase
J9312_RS03520	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J9312_RS03525	COG0823	Involved in the tonB-independent uptake of proteins
J9312_RS03545	COG2267	carboxylic ester hydrolase activity
J9312_RS03555	COG2132	Multicopper oxidase
J9312_RS03560	COG1113	amino acid transport
J9312_RS03570	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J9312_RS03575	COG0714	Associated with various cellular activities
J9312_RS03580	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
J9312_RS03585	COG1305	Transglutaminase-like
J9312_RS03595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J9312_RS03595	COG0519	Catalyzes the synthesis of GMP from XMP
J9312_RS03610	COG2252	PERMEase
J9312_RS03615	COG3064	Membrane
J9312_RS03625	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
J9312_RS03635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J9312_RS03640	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J9312_RS03645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J9312_RS03650	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J9312_RS03655	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J9312_RS03660	COG0047	phosphoribosylformylglycinamidine synthase activity
J9312_RS03665	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J9312_RS03670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J9312_RS03675	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J9312_RS03680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J9312_RS03685	COG0138	bifunctional purine biosynthesis protein purh
J9312_RS03690	COG0151	Belongs to the GarS family
J9312_RS03695	COG1522	sequence-specific DNA binding
J9312_RS03700	COG0531	amino acid
J9312_RS03710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J9312_RS03715	COG1470	cell adhesion involved in biofilm formation
J9312_RS03720	COG4496	protein, YerC YecD
J9312_RS03725	COG0069	glutamate synthase activity
J9312_RS03730	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
J9312_RS03735	COG0210	DNA helicase
J9312_RS03740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J9312_RS03745	COG4851	CamS sex pheromone cAM373 precursor
J9312_RS03755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J9312_RS03760	COG1285	pathogenesis
J9312_RS03765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J9312_RS03770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J9312_RS03775	COG0154	amidase activity
J9312_RS03780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J9312_RS03790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J9312_RS03795	COG1597	lipid kinase activity
J9312_RS03800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J9312_RS03805	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J9312_RS03830	COG5444	nuclease activity
J9312_RS03840	COG0457	Tetratricopeptide repeat
J9312_RS03850	COG0217	transcriptional regulatory protein
J9312_RS03860	COG1309	transcriptional regulator
J9312_RS03865	COG3631	Ketosteroid isomerase-related protein
J9312_RS03885	COG3546	catalase activity
J9312_RS03890	COG0454	-acetyltransferase
J9312_RS03900	COG5578	integral membrane protein
J9312_RS03905	COG2972	Histidine kinase
J9312_RS03910	COG4753	response regulator
J9312_RS03910	COG2207	Transcriptional regulator
J9312_RS03915	COG1653	transport
J9312_RS03920	COG1175	transmembrane transport
J9312_RS03925	COG0395	ABC-type sugar transport system, permease component
J9312_RS03930	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
J9312_RS03935	COG2207	Transcriptional regulator
J9312_RS03940	COG2755	lipolytic protein G-D-S-L family
J9312_RS03950	COG5578	integral membrane protein
J9312_RS03955	COG3401	FG-GAP repeat protein
J9312_RS03960	COG3401	FG-GAP repeat protein
J9312_RS03965	COG2755	lipolytic protein G-D-S-L family
J9312_RS03970	COG1874	Beta-galactosidase
J9312_RS03980	COG1653	transport
J9312_RS03985	COG4209	transmembrane transport
J9312_RS03990	COG0395	ABC-type sugar transport system, permease component
J9312_RS03995	COG1486	melibiose metabolic process
J9312_RS04000	COG2323	membrane
J9312_RS04005	COG2329	Antibiotic biosynthesis monooxygenase
J9312_RS04010	COG0346	lactoylglutathione lyase activity
J9312_RS04025	COG5583	Uncharacterized small protein (DUF2292)
J9312_RS04030	COG0670	Belongs to the BI1 family
J9312_RS04050	COG3328	transposase activity
J9312_RS04060	COG2124	cytochrome p450
J9312_RS04060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J9312_RS04065	COG1368	sulfuric ester hydrolase activity
J9312_RS04070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J9312_RS04075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J9312_RS04080	COG1442	glycosyl transferase family 8
J9312_RS04085	COG1216	Glycosyl transferase, family 2
J9312_RS04090	COG1442	glycosyl transferase family 8
J9312_RS04095	COG2223	nitrite transmembrane transporter activity
J9312_RS04100	COG1011	Hydrolase
J9312_RS04105	COG0531	amino acid
J9312_RS04110	COG1012	belongs to the aldehyde dehydrogenase family
J9312_RS04115	COG0840	transmembrane signaling receptor activity
J9312_RS04120	COG0488	(ABC) transporter
J9312_RS04130	COG0789	Transcriptional regulator
J9312_RS04135	COG2814	Major facilitator Superfamily
J9312_RS04150	COG0488	(ABC) transporter
J9312_RS04155	COG0513	Belongs to the DEAD box helicase family
J9312_RS04160	COG0456	acetyltransferase
J9312_RS04165	COG3328	transposase activity
J9312_RS04170	COG2130	NADP-dependent
J9312_RS04175	COG1120	ATPase activity
J9312_RS04180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_RS04185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_RS04190	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J9312_RS04205	COG3866	Pectate lyase
J9312_RS04210	COG0471	metal ion transport
J9312_RS04215	COG3290	protein histidine kinase activity
J9312_RS04220	COG4565	transcriptional regulatory protein
J9312_RS04225	COG3181	Tripartite tricarboxylate transporter family receptor
J9312_RS04235	COG2851	Citrate transporter
J9312_RS04240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9312_RS04245	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
J9312_RS04250	COG1254	Belongs to the acylphosphatase family
J9312_RS04255	COG2258	MOSC domain
J9312_RS04275	COG0024	Methionine aminopeptidase
J9312_RS04280	COG1263	PTS System
J9312_RS04280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_RS04285	COG1368	sulfuric ester hydrolase activity
J9312_RS04310	COG1263	PTS System
J9312_RS04310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_RS04315	COG0366	Alpha amylase catalytic
J9312_RS04320	COG2188	Transcriptional regulator
J9312_RS04325	COG0778	Nitroreductase
J9312_RS04330	COG0737	Belongs to the 5'-nucleotidase family
J9312_RS04335	COG0693	protein deglycase activity
J9312_RS04340	COG2814	Major facilitator Superfamily
J9312_RS04345	COG4840	Belongs to the UPF0435 family
J9312_RS04350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J9312_RS04355	COG4980	gas vesicle protein
J9312_RS04360	COG1295	ribonuclease BN
J9312_RS04365	COG0477	Major facilitator Superfamily
J9312_RS04370	COG0387	Pfam Sodium calcium exchanger
J9312_RS04380	COG0668	transmembrane transport
J9312_RS04385	COG0535	radical SAM domain protein
J9312_RS04395	COG0726	polysaccharide deacetylase
J9312_RS04400	COG2084	Dehydrogenase
J9312_RS04405	COG0598	Magnesium transport protein CorA
J9312_RS04410	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J9312_RS04415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J9312_RS04425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J9312_RS04430	COG4637	Psort location Cytoplasmic, score
J9312_RS04440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J9312_RS04445	COG0022	dehydrogenase e1 component
J9312_RS04450	COG0508	dehydrogenase complex catalyzes the overall conversion of
J9312_RS04455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J9312_RS04460	COG3284	Transcriptional regulator
J9312_RS04470	COG1742	UPF0060 membrane protein
J9312_RS04495	COG4842	Belongs to the WXG100 family
J9312_RS04500	COG1486	melibiose metabolic process
J9312_RS04505	COG1737	Transcriptional regulator
J9312_RS04510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_RS04510	COG1263	PTS System
J9312_RS04515	COG5434	Belongs to the glycosyl hydrolase 28 family
J9312_RS04520	COG3328	transposase activity
J9312_RS04525	COG1132	(ABC) transporter
J9312_RS04530	COG1132	(ABC) transporter
J9312_RS04535	COG2259	Doxx family
J9312_RS04540	COG2514	catechol 2,3-dioxygenase activity
J9312_RS04545	COG1917	Cupin 2, conserved barrel domain protein
J9312_RS04545	COG4977	sequence-specific DNA binding
J9312_RS04550	COG2814	Major facilitator Superfamily
J9312_RS04555	COG1082	Xylose isomerase domain protein TIM barrel
J9312_RS04565	COG4585	Histidine kinase
J9312_RS04570	COG2197	response regulator
J9312_RS04575	COG1131	(ABC) transporter
J9312_RS04585	COG0842	Transport permease protein
J9312_RS04590	COG1695	Transcriptional regulator
J9312_RS04595	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J9312_RS04600	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
J9312_RS04605	COG1309	transcriptional regulator
J9312_RS04610	COG2814	Major facilitator Superfamily
J9312_RS04615	COG2318	DinB family
J9312_RS04620	COG2814	Major facilitator Superfamily
J9312_RS04625	COG1846	Transcriptional regulator
J9312_RS04630	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
J9312_RS04630	COG0392	lysyltransferase activity
J9312_RS04635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J9312_RS04640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_RS04645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_RS04650	COG0384	phenazine biosynthesis protein PhzF
J9312_RS04655	COG0778	Nitroreductase
J9312_RS04670	COG1090	epimerase
J9312_RS04675	COG2137	regulation of response to DNA damage stimulus
J9312_RS04685	COG2814	Major facilitator Superfamily
J9312_RS04705	COG3103	Sh3 type 3 domain protein
J9312_RS04710	COG5658	integral membrane protein
J9312_RS04715	COG0596	Alpha beta hydrolase
J9312_RS04720	COG0463	Glycosyl transferase, family 2
J9312_RS04725	COG4485	Bacterial membrane protein, YfhO
J9312_RS04730	COG1988	membrane-bound metal-dependent
J9312_RS04735	COG1194	a g-specific adenine glycosylase
J9312_RS04745	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS04760	COG3557	Belongs to the UPF0374 family
J9312_RS04765	COG1132	(ABC) transporter
J9312_RS04770	COG4129	membrane
J9312_RS04775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J9312_RS04780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J9312_RS04785	COG0735	belongs to the Fur family
J9312_RS04895	COG4326	sporulation control protein
J9312_RS04905	COG5577	PFAM Coat F domain
J9312_RS04910	COG3340	Belongs to the peptidase S51 family
J9312_RS04915	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J9312_RS04930	COG0753	catalase activity
J9312_RS04935	COG1116	anion transmembrane transporter activity
J9312_RS04940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J9312_RS04945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J9312_RS04960	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J9312_RS04970	COG1476	TRANSCRIPTIONal
J9312_RS04980	COG3382	B3 4 domain protein
J9312_RS04985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J9312_RS04995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J9312_RS05000	COG0789	Transcriptional regulator
J9312_RS05005	COG1664	Polymer-forming cytoskeletal
J9312_RS05010	COG1664	Polymer-forming cytoskeletal
J9312_RS05015	COG2766	serine protein kinase
J9312_RS05020	COG2718	Belongs to the UPF0229 family
J9312_RS05025	COG1846	Transcriptional regulator
J9312_RS05030	COG1566	PFAM secretion protein HlyD family protein
J9312_RS05035	COG2814	Major facilitator Superfamily
J9312_RS05040	COG0655	NAD(P)H dehydrogenase (quinone) activity
J9312_RS05060	COG1725	Transcriptional regulator
J9312_RS05065	COG1131	(ABC) transporter
J9312_RS05070	COG1131	(ABC) transporter
J9312_RS05075	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J9312_RS05080	COG1278	Cold shock
J9312_RS05085	COG1464	Belongs to the NlpA lipoprotein family
J9312_RS05090	COG3706	GGDEF domain
J9312_RS05095	COG1823	symporter activity
J9312_RS05100	COG5444	nuclease activity
J9312_RS05125	COG0582	viral genome integration into host DNA
J9312_RS05190	COG5644	endopeptidase inhibitor activity
J9312_RS05195	COG0741	lytic transglycosylase activity
J9312_RS05195	COG0791	NLP P60 protein
J9312_RS05215	COG0457	Tetratricopeptide repeat
J9312_RS05235	COG4085	toxin activity
J9312_RS05235	COG1525	nuclease
J9312_RS05235	COG0737	Belongs to the 5'-nucleotidase family
J9312_RS05240	COG3764	Sortase (surface protein transpeptidase)
J9312_RS05245	COG0564	pseudouridine synthase activity
J9312_RS05255	COG0517	IMP dehydrogenase activity
J9312_RS05260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J9312_RS05265	COG3153	acetyltransferase
J9312_RS05265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J9312_RS05270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J9312_RS05275	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
J9312_RS05280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J9312_RS05285	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J9312_RS05290	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J9312_RS05295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J9312_RS05300	COG4585	Histidine kinase
J9312_RS05300	COG2203	Gaf domain
J9312_RS05305	COG2197	response regulator
J9312_RS05310	COG0431	NADPH-dependent FMN reductase
J9312_RS05325	COG1388	LysM domain
J9312_RS05325	COG0791	NLP P60 protein
J9312_RS05330	COG1959	2 iron, 2 sulfur cluster binding
J9312_RS05335	COG0668	transmembrane transport
J9312_RS05340	COG2719	SpoVR family
J9312_RS05345	COG1785	Belongs to the alkaline phosphatase family
J9312_RS05350	COG1388	LysM domain
J9312_RS05350	COG0791	NLP P60 protein
J9312_RS05355	COG0583	DNA-binding transcription factor activity
J9312_RS05360	COG0372	Belongs to the citrate synthase family
J9312_RS05365	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS05370	COG0531	amino acid
J9312_RS05375	COG0733	neurotransmitter:sodium symporter activity
J9312_RS05380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_RS05385	COG0456	acetyltransferase
J9312_RS05400	COG1595	DNA-templated transcription, initiation
J9312_RS05405	COG0667	Aldo Keto reductase
J9312_RS05410	COG0204	Acyl-transferase
J9312_RS05415	COG1253	flavin adenine dinucleotide binding
J9312_RS05420	COG0789	Transcriptional regulator
J9312_RS05430	COG1253	flavin adenine dinucleotide binding
J9312_RS05435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J9312_RS05440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J9312_RS05445	COG0584	glycerophosphoryl diester phosphodiesterase
J9312_RS05455	COG0668	transmembrane transport
J9312_RS05460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J9312_RS05465	COG0726	polysaccharide deacetylase
J9312_RS05470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J9312_RS05475	COG1757	Na H antiporter
J9312_RS05480	COG0589	response to stress
J9312_RS05490	COG1132	(ABC) transporter
J9312_RS05495	COG1132	(ABC) transporter
J9312_RS05500	COG0702	epimerase
J9312_RS05520	COG0189	ligase activity
J9312_RS05525	COG0189	ligase activity
J9312_RS05530	COG4399	Belongs to the UPF0754 family
J9312_RS05535	COG3679	Belongs to the UPF0342 family
J9312_RS05540	COG4335	DNA alkylation repair
J9312_RS05545	COG0561	phosphatase activity
J9312_RS05550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J9312_RS05555	COG0475	glutathione-regulated potassium exporter activity
J9312_RS05560	COG0490	domain, Protein
J9312_RS05570	COG1024	Enoyl-CoA hydratase
J9312_RS05580	COG4152	abc transporter atp-binding protein
J9312_RS05585	COG1668	transmembrane transport
J9312_RS05590	COG0420	3'-5' exonuclease activity
J9312_RS05595	COG4717	serine-type aminopeptidase activity
J9312_RS05600	COG3481	metal-dependent phosphohydrolase, HD sub domain
J9312_RS05610	COG3328	transposase activity
J9312_RS05615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J9312_RS05645	COG1846	Transcriptional regulator
J9312_RS05650	COG4980	gas vesicle protein
J9312_RS05665	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J9312_RS05670	COG0537	adenosine 5'-monophosphoramidase activity
J9312_RS05675	COG1131	(ABC) transporter
J9312_RS05680	COG4473	ABC transporter
J9312_RS05690	COG1473	amidohydrolase
J9312_RS05695	COG3069	C4-dicarboxylate transmembrane transporter activity
J9312_RS05705	COG2329	Antibiotic biosynthesis monooxygenase
J9312_RS05710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J9312_RS05715	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J9312_RS05720	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J9312_RS05725	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
J9312_RS05730	COG1309	transcriptional regulator
J9312_RS05735	COG1511	domain protein
J9312_RS05740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J9312_RS05745	COG4377	Putative membrane peptidase family (DUF2324)
J9312_RS05755	COG1363	Peptidase, m42
J9312_RS05760	COG4405	Protein conserved in bacteria
J9312_RS05765	COG1301	dicarboxylic acid transport
J9312_RS05775	COG1234	tRNA 3'-trailer cleavage
J9312_RS05780	COG0095	Lipoate-protein ligase
J9312_RS05785	COG0702	epimerase
J9312_RS05790	COG0318	PFAM AMP-dependent synthetase and ligase
J9312_RS05800	COG0501	Belongs to the peptidase M48B family
J9312_RS05805	COG1404	Belongs to the peptidase S8 family
J9312_RS05810	COG0456	acetyltransferase
J9312_RS05815	COG0604	alcohol dehydrogenase
J9312_RS05820	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J9312_RS05825	COG0406	alpha-ribazole phosphatase activity
J9312_RS05830	COG0183	Belongs to the thiolase family
J9312_RS05835	COG0318	PFAM AMP-dependent synthetase and ligase
J9312_RS05840	COG1268	BioY protein
J9312_RS05845	COG0840	transmembrane signaling receptor activity
J9312_RS05855	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS05865	COG4903	ComK protein
J9312_RS05870	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS05880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J9312_RS05895	COG0398	Pfam SNARE associated Golgi protein
J9312_RS05900	COG0681	Belongs to the peptidase S26 family
J9312_RS05905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J9312_RS05910	COG1846	Transcriptional regulator
J9312_RS05920	COG0738	Major facilitator superfamily
J9312_RS05955	COG0561	phosphatase activity
J9312_RS05960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J9312_RS05965	COG1609	Transcriptional regulator
J9312_RS05970	COG3180	Ammonia monooxygenase
J9312_RS05975	COG0477	Major facilitator Superfamily
J9312_RS05975	COG2814	Major facilitator Superfamily
J9312_RS05980	COG4533	DNA binding
J9312_RS05990	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
J9312_RS05995	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
J9312_RS06000	COG1074	ATP-dependent DNA helicase activity
J9312_RS06005	COG0420	3'-5' exonuclease activity
J9312_RS06010	COG0419	ATPase involved in DNA repair
J9312_RS06015	COG1403	HNH endonuclease
J9312_RS06055	COG5337	Spore coat protein CotH
J9312_RS06060	COG0179	Fumarylacetoacetate (FAA) hydrolase
J9312_RS06070	COG1404	Belongs to the peptidase S8 family
J9312_RS06080	COG0367	asparagine synthase
J9312_RS06090	COG0534	Mate efflux family protein
J9312_RS06095	COG1917	Cupin 2, conserved barrel domain protein
J9312_RS06095	COG2207	Transcriptional regulator
J9312_RS06100	COG1609	Transcriptional regulator
J9312_RS06105	COG0673	inositol 2-dehydrogenase activity
J9312_RS06110	COG2318	DinB family
J9312_RS06120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9312_RS06125	COG1357	PFAM Pentapeptide repeats (8 copies)
J9312_RS06130	COG2267	carboxylic ester hydrolase activity
J9312_RS06135	COG0529	Catalyzes the synthesis of activated sulfate
J9312_RS06145	COG0175	sulfate reduction
J9312_RS06150	COG2045	Belongs to the ComB family
J9312_RS06155	COG1809	phosphosulfolactate synthase activity
J9312_RS06160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_RS06165	COG4948	Mandelate Racemase Muconate Lactonizing
J9312_RS06170	COG2814	Major facilitator Superfamily
J9312_RS06175	COG0454	-acetyltransferase
J9312_RS06180	COG2153	protein acetylation
J9312_RS06185	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J9312_RS06185	COG0646	methionine synthase
J9312_RS06190	COG1666	GTP binding
J9312_RS06195	COG2996	Protein conserved in bacteria
J9312_RS06215	COG1695	Transcriptional regulator
J9312_RS06230	COG3227	Zinc metalloprotease (Elastase)
J9312_RS06235	COG1307	EDD domain protein, DegV family
J9312_RS06240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_RS06260	COG0561	phosphatase activity
J9312_RS06265	COG1073	alpha beta
J9312_RS06270	COG2151	metal-sulfur cluster biosynthetic enzyme
J9312_RS06280	COG0277	FAD linked oxidase domain protein
J9312_RS06290	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J9312_RS06295	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J9312_RS06305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J9312_RS06310	COG0505	Belongs to the CarA family
J9312_RS06315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J9312_RS06320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J9312_RS06340	COG2267	carboxylic ester hydrolase activity
J9312_RS06350	COG1744	ABC transporter substrate-binding protein PnrA-like
J9312_RS06365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J9312_RS06370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J9312_RS06375	COG5504	Zn-dependent protease
J9312_RS06380	COG0444	Belongs to the ABC transporter superfamily
J9312_RS06385	COG4608	Belongs to the ABC transporter superfamily
J9312_RS06395	COG0601	transmembrane transport
J9312_RS06400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J9312_RS06410	COG0180	Tryptophanyl-tRNA synthetase
J9312_RS06415	COG4166	transmembrane transport
J9312_RS06420	COG0601	transmembrane transport
J9312_RS06425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J9312_RS06430	COG0444	Belongs to the ABC transporter superfamily
J9312_RS06435	COG4608	Belongs to the ABC transporter superfamily
J9312_RS06440	COG2814	Major facilitator Superfamily
J9312_RS06445	COG0456	acetyltransferase
J9312_RS06450	COG1393	Belongs to the ArsC family
J9312_RS06455	COG0861	Integral membrane protein TerC family
J9312_RS06465	COG4862	establishment of competence for transformation
J9312_RS06475	COG4469	Competence protein
J9312_RS06480	COG1164	Oligoendopeptidase f
J9312_RS06490	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J9312_RS06495	COG2346	COG2346, Truncated hemoglobins
J9312_RS06500	COG0741	lytic transglycosylase activity
J9312_RS06505	COG4116	CYTH
J9312_RS06515	COG2357	RelA SpoT domain protein
J9312_RS06520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J9312_RS06525	COG0564	pseudouridine synthase activity
J9312_RS06530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J9312_RS06535	COG0569	domain protein
J9312_RS06535	COG0475	glutathione-regulated potassium exporter activity
J9312_RS06540	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J9312_RS06545	COG0352	thiamine-phosphate diphosphorylase activity
J9312_RS06550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J9312_RS06555	COG2104	thiamine diphosphate biosynthetic process
J9312_RS06560	COG2022	thiamine diphosphate biosynthetic process
J9312_RS06565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J9312_RS06570	COG0351	phosphomethylpyrimidine kinase
J9312_RS06575	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J9312_RS06630	COG0210	DNA helicase
J9312_RS06645	COG2153	protein acetylation
J9312_RS06650	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
J9312_RS06655	COG2382	esterase
J9312_RS06660	COG0626	cystathionine gamma-synthase activity
J9312_RS06665	COG0626	cystathionine gamma-synthase activity
J9312_RS06670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_RS06675	COG5505	Protein of unknown function (DUF819)
J9312_RS06715	COG1396	sequence-specific DNA binding
J9312_RS06795	COG0457	Tetratricopeptide repeat
J9312_RS06800	COG5444	nuclease activity
J9312_RS06815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_RS06825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J9312_RS06840	COG0109	protoheme IX farnesyltransferase activity
J9312_RS06850	COG0726	polysaccharide deacetylase
J9312_RS06865	COG5504	Zn-dependent protease
J9312_RS06870	COG2205	protein histidine kinase activity
J9312_RS06880	COG3383	formate dehydrogenase (NAD+) activity
J9312_RS06895	COG1051	belongs to the nudix hydrolase family
J9312_RS06905	COG2124	cytochrome p450
J9312_RS06910	COG1819	glycosyl
J9312_RS06920	COG1587	Uroporphyrinogen-III synthase
J9312_RS06925	COG0390	transport system, permease component
J9312_RS06930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J9312_RS06935	COG0697	spore germination
J9312_RS06940	COG4297	protein containing double-stranded beta helix domain
J9312_RS06950	COG1252	NADH dehydrogenase
J9312_RS06955	COG1904	glucuronate isomerase
J9312_RS06960	COG2211	Major facilitator Superfamily
J9312_RS06965	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J9312_RS06970	COG1063	alcohol dehydrogenase
J9312_RS06975	COG1312	Catalyzes the dehydration of D-mannonate
J9312_RS06980	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS06985	COG2271	Major facilitator Superfamily
J9312_RS06990	COG1609	Transcriptional regulator
J9312_RS06995	COG0246	Mannitol dehydrogenase
J9312_RS07000	COG2721	sulfolactate sulfo-lyase activity
J9312_RS07005	COG0730	response to heat
J9312_RS07010	COG2318	DinB family
J9312_RS07015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J9312_RS07020	COG0457	Tetratricopeptide repeat
J9312_RS07035	COG5632	N-Acetylmuramoyl-L-alanine amidase
J9312_RS07035	COG3409	Peptidoglycan-binding domain 1 protein
J9312_RS07035	COG1388	LysM domain
J9312_RS07045	COG4195	phage-related replication protein
J9312_RS07050	COG3546	catalase activity
J9312_RS07055	COG2856	Zn peptidase
J9312_RS07060	COG1396	sequence-specific DNA binding
J9312_RS07070	COG1522	sequence-specific DNA binding
J9312_RS07075	COG1484	DNA-dependent DNA replication
J9312_RS07095	COG1595	DNA-templated transcription, initiation
J9312_RS07100	COG3728	DNA packaging
J9312_RS07100	COG5484	DNA packaging
J9312_RS07105	COG1783	phage Terminase large subunit
J9312_RS07110	COG5518	Phage portal protein
J9312_RS07115	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J9312_RS07120	COG4653	Phage capsid family
J9312_RS07170	COG3953	SLT domain
J9312_RS07170	COG5412	phage tail tape measure protein
J9312_RS07170	COG3953	SLT domain
J9312_RS07170	COG5412	phage tail tape measure protein
J9312_RS07170	COG3953	SLT domain
J9312_RS07170	COG5412	phage tail tape measure protein
J9312_RS07180	COG4193	domain, Protein
J9312_RS07190	COG3628	GPW Gp25 family protein
J9312_RS07195	COG3299	homolog of phage Mu protein gp47
J9312_RS07200	COG3778	Protein conserved in bacteria
J9312_RS07240	COG3409	Peptidoglycan-binding domain 1 protein
J9312_RS07240	COG5632	N-Acetylmuramoyl-L-alanine amidase
J9312_RS07260	COG0306	phosphate transporter
J9312_RS07265	COG1392	Phosphate transport regulator
J9312_RS07275	COG0346	lactoylglutathione lyase activity
J9312_RS07285	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J9312_RS07290	COG0463	Glycosyl transferase, family 2
J9312_RS07300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9312_RS07305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J9312_RS07310	COG2362	D-Aminopeptidase
J9312_RS07315	COG0601	transmembrane transport
J9312_RS07320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J9312_RS07325	COG0444	Belongs to the ABC transporter superfamily
J9312_RS07330	COG4166	transmembrane transport
J9312_RS07335	COG1619	proteins homologs of microcin C7 resistance protein MccF
J9312_RS07340	COG4948	Mandelate Racemase Muconate Lactonizing
J9312_RS07345	COG0791	NLP P60 protein
J9312_RS07350	COG4608	Belongs to the ABC transporter superfamily
J9312_RS07355	COG2706	6-phosphogluconolactonase activity
J9312_RS07365	COG1607	acyl-coa hydrolase
J9312_RS07370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J9312_RS07370	COG1017	nitric oxide dioxygenase activity
J9312_RS07380	COG2323	membrane
J9312_RS07385	COG2318	DinB family
J9312_RS07390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_RS07395	COG2076	Multidrug Resistance protein
J9312_RS07400	COG2076	Multidrug Resistance protein
J9312_RS07405	COG0788	formyltetrahydrofolate deformylase activity
J9312_RS07410	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J9312_RS07415	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J9312_RS07420	COG1764	response to oxidative stress
J9312_RS07425	COG1846	Transcriptional regulator
J9312_RS07430	COG1764	response to oxidative stress
J9312_RS07440	COG0590	tRNA wobble adenosine to inosine editing
J9312_RS07445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J9312_RS07450	COG1404	Belongs to the peptidase S8 family
J9312_RS07455	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_RS07460	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J9312_RS07465	COG1122	ATPase activity
J9312_RS07470	COG4721	ABC-type cobalt transport system, permease component
J9312_RS07480	COG0745	RESPONSE REGULATOR receiver
J9312_RS07485	COG5002	protein histidine kinase activity
J9312_RS07485	COG3850	Histidine kinase
J9312_RS07490	COG3212	peptidase
J9312_RS07495	COG3212	peptidase
J9312_RS07510	COG2239	Acts as a magnesium transporter
J9312_RS07515	COG0789	Transcriptional regulator
J9312_RS07530	COG1846	Transcriptional regulator
J9312_RS07540	COG0726	polysaccharide deacetylase
J9312_RS07545	COG1408	metallophosphoesterase
J9312_RS07555	COG0463	Glycosyl transferase, family 2
J9312_RS07560	COG1793	dna ligase
J9312_RS07560	COG3285	dna ligase
J9312_RS07565	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
J9312_RS07570	COG3300	MHYT domain
J9312_RS07570	COG5001	Diguanylate cyclase
J9312_RS07575	COG0586	Pfam SNARE associated Golgi protein
J9312_RS07580	COG0861	Integral membrane protein TerC family
J9312_RS07585	COG1191	sigma factor activity
J9312_RS07605	COG0501	Belongs to the peptidase M48B family
J9312_RS07610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J9312_RS07625	COG3594	Acyltransferase
J9312_RS07630	COG5002	protein histidine kinase activity
J9312_RS07635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J9312_RS07645	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
J9312_RS07650	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
J9312_RS07655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J9312_RS07660	COG0436	Aminotransferase
J9312_RS07665	COG1850	ribulose-bisphosphate carboxylase activity
J9312_RS07670	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
J9312_RS07675	COG0235	Class ii aldolase
J9312_RS07680	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
J9312_RS07685	COG3339	Conserved Protein
J9312_RS07700	COG3852	Histidine kinase
J9312_RS07705	COG1846	Transcriptional regulator
J9312_RS07710	COG1360	Flagellar Motor Protein
J9312_RS07715	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J9312_RS07720	COG0542	response to heat
J9312_RS07725	COG3949	Membrane
J9312_RS07730	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J9312_RS07735	COG0720	synthase
J9312_RS07740	COG0602	queuosine metabolic process
J9312_RS07745	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J9312_RS07750	COG1733	regulation of RNA biosynthetic process
J9312_RS07755	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS07790	COG0582	viral genome integration into host DNA
J9312_RS07820	COG3858	chitin binding
J9312_RS07825	COG3858	chitin binding
J9312_RS07835	COG4873	Protein conserved in bacteria
J9312_RS07845	COG3773	Cell wall hydrolase
J9312_RS07850	COG2244	polysaccharide biosynthetic process
J9312_RS07855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_RS07860	COG2217	Heavy metal translocating P-type atpase
J9312_RS07870	COG0006	proline dipeptidase activity
J9312_RS07875	COG1609	Transcriptional regulator
J9312_RS07880	COG3711	transcriptional antiterminator
J9312_RS07885	COG1263	PTS System
J9312_RS07885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_RS07885	COG2190	(PTS) system
J9312_RS07890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_RS07895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J9312_RS07905	COG1533	DNA photolyase activity
J9312_RS07910	COG0456	acetyltransferase
J9312_RS07915	COG0840	transmembrane signaling receptor activity
J9312_RS07920	COG2084	Dehydrogenase
J9312_RS07925	COG3328	transposase activity
J9312_RS07930	COG2340	Cysteine-rich secretory protein family
J9312_RS07935	COG0768	penicillin binding
J9312_RS07940	COG4191	Histidine kinase
J9312_RS07945	COG0436	Aminotransferase
J9312_RS07955	COG0784	Response regulator, receiver
J9312_RS07955	COG0835	chemotaxis
J9312_RS07965	COG2814	Major facilitator Superfamily
J9312_RS07970	COG1376	ErfK ybiS ycfS ynhG family protein
J9312_RS07975	COG1408	metallophosphoesterase
J9312_RS07980	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS07985	COG2200	EAL domain
J9312_RS07990	COG4703	Protein of unknown function (DUF1797)
J9312_RS07995	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
J9312_RS08005	COG0517	IMP dehydrogenase activity
J9312_RS08010	COG0583	DNA-binding transcription factor activity
J9312_RS08015	COG0716	FMN binding
J9312_RS08025	COG0716	FMN binding
J9312_RS08030	COG2171	N-acyltransferase activity
J9312_RS08035	COG1473	amidohydrolase
J9312_RS08045	COG0668	transmembrane transport
J9312_RS08050	COG0450	alkyl hydroperoxide reductase
J9312_RS08055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_RS08070	COG0746	molybdenum cofactor guanylyltransferase activity
J9312_RS08075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J9312_RS08080	COG0303	'Molybdopterin
J9312_RS08085	COG1763	Mo-molybdopterin cofactor biosynthetic process
J9312_RS08090	COG0314	molybdopterin synthase activity
J9312_RS08095	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J9312_RS08100	COG1132	(ABC) transporter
J9312_RS08105	COG1132	(ABC) transporter
J9312_RS08115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J9312_RS08120	COG1136	(ABC) transporter
J9312_RS08125	COG0577	efflux transmembrane transporter activity
J9312_RS08130	COG1349	DNA-binding transcription factor activity
J9312_RS08135	COG1105	Belongs to the carbohydrate kinase PfkB family
J9312_RS08140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J9312_RS08140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J9312_RS08140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_RS08145	COG0681	Belongs to the peptidase S26 family
J9312_RS08155	COG0488	(ABC) transporter
J9312_RS08160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J9312_RS08165	COG2309	aminopeptidase activity
J9312_RS08175	COG1077	Cell shape determining protein MreB Mrl
J9312_RS08180	COG2002	toxin-antitoxin pair type II binding
J9312_RS08185	COG3852	Histidine kinase
J9312_RS08190	COG2105	PFAM AIG2 family protein
J9312_RS08190	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
J9312_RS08195	COG0569	domain protein
J9312_RS08200	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J9312_RS08205	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J9312_RS08210	COG5503	Protein of unknown function (DUF1447)
J9312_RS08215	COG0561	phosphatase activity
J9312_RS08220	COG0242	peptide deformylase activity
J9312_RS08235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J9312_RS08240	COG0022	dehydrogenase e1 component
J9312_RS08245	COG0508	dehydrogenase complex catalyzes the overall conversion of
J9312_RS08250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J9312_RS08255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_RS08265	COG1982	Orn Lys Arg decarboxylase major
J9312_RS08270	COG4476	Belongs to the UPF0223 family
J9312_RS08275	COG4493	Belongs to the UPF0637 family
J9312_RS08285	COG0483	inositol monophosphate 1-phosphatase activity
J9312_RS08295	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
J9312_RS08315	COG1595	DNA-templated transcription, initiation
J9312_RS08335	COG1217	gtp-binding protein TYPA
J9312_RS08345	COG4896	Protein conserved in bacteria
J9312_RS08355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J9312_RS08360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J9312_RS08365	COG2066	Belongs to the glutaminase family
J9312_RS08370	COG4838	Belongs to the UPF0358 family
J9312_RS08375	COG0772	Belongs to the SEDS family
J9312_RS08380	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J9312_RS08385	COG1612	heme a metabolic process
J9312_RS08390	COG0109	protoheme IX farnesyltransferase activity
J9312_RS08395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J9312_RS08395	COG2010	Cytochrome c
J9312_RS08400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J9312_RS08405	COG1845	cytochrome c oxidase, subunit III
J9312_RS08410	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J9312_RS08415	COG3336	cytochrome c oxidase
J9312_RS08425	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
J9312_RS08430	COG2340	Cysteine-rich secretory protein family
J9312_RS08445	COG3679	Belongs to the UPF0342 family
J9312_RS08450	COG4471	UPF0298 protein
J9312_RS08455	COG0742	ribosomal rna small subunit methyltransferase
J9312_RS08460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J9312_RS08465	COG3314	Sporulation integral membrane protein YlbJ
J9312_RS08470	COG1752	Esterase of the alpha-beta hydrolase superfamily
J9312_RS08475	COG3480	Lon protease (S16) C-terminal proteolytic domain
J9312_RS08480	COG1323	Belongs to the UPF0348 family
J9312_RS08490	COG1399	metal-binding, possibly nucleic acid-binding protein
J9312_RS08505	COG0454	-acetyltransferase
J9312_RS08510	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J9312_RS08515	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
J9312_RS08520	COG2001	Belongs to the MraZ family
J9312_RS08525	COG0275	rRNA processing
J9312_RS08530	COG4839	cell division protein FtsL
J9312_RS08535	COG0768	penicillin binding
J9312_RS08540	COG0768	penicillin binding
J9312_RS08545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J9312_RS08550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J9312_RS08555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J9312_RS08560	COG0772	Belongs to the SEDS family
J9312_RS08565	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J9312_RS08570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J9312_RS08575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J9312_RS08580	COG3879	Bacterial protein of unknown function (DUF881)
J9312_RS08585	COG3879	Bacterial protein of unknown function (DUF881)
J9312_RS08590	COG3856	small basic protein
J9312_RS08595	COG0849	cell division
J9312_RS08600	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J9312_RS08605	COG4412	M6 family metalloprotease domain protein
J9312_RS08605	COG1404	Belongs to the peptidase S8 family
J9312_RS08615	COG1191	sigma factor activity
J9312_RS08620	COG1191	sigma factor activity
J9312_RS08625	COG1119	ATPase activity
J9312_RS08630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J9312_RS08635	COG1873	PFAM PRC-barrel domain
J9312_RS08640	COG1496	oxidoreductase activity
J9312_RS08645	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J9312_RS08650	COG1799	cell septum assembly
J9312_RS08655	COG0762	integral membrane protein
J9312_RS08660	COG2302	S4 RNA-binding domain
J9312_RS08665	COG3599	regulation of cell shape
J9312_RS08670	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J9312_RS08675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J9312_RS08680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J9312_RS08685	COG0564	pseudouridine synthase activity
J9312_RS08690	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J9312_RS08695	COG2233	PERMEase
J9312_RS08700	COG0540	Belongs to the ATCase OTCase family
J9312_RS08705	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J9312_RS08710	COG0505	Belongs to the CarA family
J9312_RS08715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J9312_RS08720	COG0543	2 iron, 2 sulfur cluster binding
J9312_RS08725	COG0167	dihydroorotate dehydrogenase activity
J9312_RS08730	COG0284	orotidine-5'-phosphate decarboxylase activity
J9312_RS08735	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J9312_RS08740	COG0175	sulfate reduction
J9312_RS08745	COG0306	phosphate transporter
J9312_RS08750	COG2046	Belongs to the sulfate adenylyltransferase family
J9312_RS08755	COG0529	Catalyzes the synthesis of activated sulfate
J9312_RS08760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J9312_RS08765	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
J9312_RS08770	COG1648	precorrin-2 dehydrogenase activity
J9312_RS08775	COG1293	RNA-binding protein homologous to eukaryotic snRNP
J9312_RS08780	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J9312_RS08785	COG1561	YicC-like family, N-terminal region
J9312_RS08795	COG0194	GDP metabolic process
J9312_RS08800	COG1758	RNA polymerase activity
J9312_RS08805	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J9312_RS08810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J9312_RS08815	COG0242	peptide deformylase activity
J9312_RS08820	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J9312_RS08825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J9312_RS08825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J9312_RS08830	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J9312_RS08835	COG0631	protein serine/threonine phosphatase activity
J9312_RS08840	COG0515	serine threonine protein kinase
J9312_RS08840	COG2815	serine threonine protein kinase
J9312_RS08845	COG1162	GTPase activity
J9312_RS08850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J9312_RS08855	COG1564	THIamine pyrophosphokinase
J9312_RS08865	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J9312_RS08870	COG1302	Protein conserved in bacteria
J9312_RS08875	COG1461	Dihydroxyacetone kinase
J9312_RS08880	COG1760	l-serine dehydratase
J9312_RS08885	COG1760	l-serine dehydratase
J9312_RS08890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J9312_RS08895	COG1349	DNA-binding transcription factor activity
J9312_RS08895	COG2050	protein possibly involved in aromatic compounds catabolism
J9312_RS08900	COG0416	fatty acid biosynthetic process
J9312_RS08905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J9312_RS08910	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS08920	COG0571	ribonuclease III activity
J9312_RS08925	COG1196	nuclear chromosome segregation
J9312_RS08930	COG0552	protein localization to endoplasmic reticulum
J9312_RS08940	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
J9312_RS08945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J9312_RS08950	COG0228	four-way junction DNA binding
J9312_RS08955	COG1837	Belongs to the UPF0109 family
J9312_RS08965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J9312_RS08970	COG0336	Belongs to the RNA methyltransferase TrmD family
J9312_RS08975	COG0335	large ribosomal subunit rRNA binding
J9312_RS08980	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J9312_RS08985	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J9312_RS08995	COG2257	FlhB HrpN YscU SpaS Family
J9312_RS09000	COG0045	succinate-CoA ligase (ADP-forming) activity
J9312_RS09005	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J9312_RS09010	COG0758	DNA mediated transformation
J9312_RS09015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J9312_RS09020	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
J9312_RS09025	COG4974	Belongs to the 'phage' integrase family
J9312_RS09030	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J9312_RS09035	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J9312_RS09040	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
J9312_RS09045	COG1815	bacterial-type flagellum-dependent cell motility
J9312_RS09050	COG1558	bacterial-type flagellum-dependent cell motility
J9312_RS09055	COG1677	Flagellar hook-basal body complex protein FliE
J9312_RS09060	COG1766	The M ring may be actively involved in energy transduction
J9312_RS09065	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J9312_RS09070	COG1317	bacterial-type flagellum organization
J9312_RS09075	COG1157	protein secretion by the type III secretion system
J9312_RS09080	COG2882	bacterial-type flagellum organization
J9312_RS09085	COG3334	PFAM MgtE intracellular
J9312_RS09090	COG3144	bacterial-type flagellum assembly
J9312_RS09095	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J9312_RS09100	COG4786	Flagellar basal body rod
J9312_RS09105	COG1582	Flagellar protein (FlbD)
J9312_RS09110	COG1580	Controls the rotational direction of flagella during chemotaxis
J9312_RS09115	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J9312_RS09120	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J9312_RS09120	COG1776	CheC inhibitor of MCP methylation
J9312_RS09125	COG2201	protein-glutamate methylesterase activity
J9312_RS09130	COG3190	flagellar
J9312_RS09135	COG1338	Plays a role in the flagellum-specific transport system
J9312_RS09140	COG1987	bacterial-type flagellum assembly
J9312_RS09145	COG1684	flagellar biosynthetic protein fliR
J9312_RS09150	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J9312_RS09155	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J9312_RS09160	COG1419	protein localization to endoplasmic reticulum
J9312_RS09165	COG0455	bacterial-type flagellum organization
J9312_RS09170	COG2201	protein-glutamate methylesterase activity
J9312_RS09175	COG2198	Histidine kinase
J9312_RS09175	COG0643	Histidine kinase
J9312_RS09180	COG0835	chemotaxis
J9312_RS09185	COG1776	CheC inhibitor of MCP methylation
J9312_RS09190	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
J9312_RS09195	COG1191	sigma factor activity
J9312_RS09205	COG0052	Belongs to the universal ribosomal protein uS2 family
J9312_RS09210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J9312_RS09215	COG0528	UMP kinase activity
J9312_RS09220	COG0233	cytoplasmic translational termination
J9312_RS09225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J9312_RS09230	COG4589	Belongs to the CDS family
J9312_RS09235	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J9312_RS09240	COG0750	zinc metalloprotease
J9312_RS09245	COG0442	prolyl-tRNA aminoacylation
J9312_RS09250	COG2176	DNA-directed DNA polymerase activity
J9312_RS09255	COG0779	Required for maturation of 30S ribosomal subunits
J9312_RS09260	COG0195	Participates in both transcription termination and antitermination
J9312_RS09265	COG2740	Nucleic-acid-binding protein implicated in transcription termination
J9312_RS09270	COG1358	cellular component organization or biogenesis
J9312_RS09275	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J9312_RS09280	COG1550	Protein conserved in bacteria
J9312_RS09285	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J9312_RS09290	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J9312_RS09295	COG0196	riboflavin kinase activity
J9312_RS09300	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J9312_RS09305	COG1185	polyribonucleotide nucleotidyltransferase activity
J9312_RS09310	COG0726	polysaccharide deacetylase
J9312_RS09315	COG0612	Peptidase, M16
J9312_RS09320	COG1873	PFAM PRC-barrel domain
J9312_RS09325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J9312_RS09330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J9312_RS09335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J9312_RS09340	COG0527	aspartate kinase activity
J9312_RS09345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J9312_RS09350	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J9312_RS09355	COG0740	serine-type endopeptidase activity
J9312_RS09365	COG1674	ftsk spoiiie
J9312_RS09365	COG4980	gas vesicle protein
J9312_RS09370	COG2188	Transcriptional regulator
J9312_RS09375	COG2814	Major facilitator Superfamily
J9312_RS09380	COG0612	Peptidase, M16
J9312_RS09385	COG0612	Peptidase, M16
J9312_RS09390	COG0300	oxidoreductase activity
J9312_RS09405	COG1426	Protein conserved in bacteria
J9312_RS09410	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J9312_RS09415	COG1546	Belongs to the CinA family
J9312_RS09415	COG1058	Belongs to the CinA family
J9312_RS09420	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J9312_RS09425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J9312_RS09430	COG1418	mRNA catabolic process
J9312_RS09435	COG1692	metallophosphoesterase
J9312_RS09440	COG2359	stage V sporulation protein S
J9312_RS09445	COG1063	alcohol dehydrogenase
J9312_RS09450	COG0156	8-amino-7-oxononanoate synthase activity
J9312_RS09455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J9312_RS09460	COG4550	Control of competence regulator ComK, YlbF/YmcA
J9312_RS09470	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J9312_RS09475	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J9312_RS09600	COG3226	Transcriptional regulator
J9312_RS09610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9312_RS09615	COG1404	Belongs to the peptidase S8 family
J9312_RS09625	COG4195	phage-related replication protein
J9312_RS09630	COG1764	response to oxidative stress
J9312_RS09635	COG2076	Multidrug Resistance protein
J9312_RS09640	COG2076	Multidrug Resistance protein
J9312_RS09655	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J9312_RS09660	COG1923	regulation of RNA biosynthetic process
J9312_RS09675	COG1780	Probably involved in ribonucleotide reductase function
J9312_RS09680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J9312_RS09685	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J9312_RS09690	COG4112	unkown
J9312_RS09695	COG0860	N-Acetylmuramoyl-L-alanine amidase
J9312_RS09700	COG0464	growth
J9312_RS09705	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J9312_RS09710	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
J9312_RS09715	COG0789	Transcriptional regulator
J9312_RS09720	COG0174	glutamine synthetase
J9312_RS09740	COG5444	nuclease activity
J9312_RS09765	COG4282	regulation of fungal-type cell wall biogenesis
J9312_RS09775	COG3328	transposase activity
J9312_RS09785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_RS09800	COG3655	Transcriptional regulator
J9312_RS09825	COG0135	phosphoribosylanthranilate isomerase activity
J9312_RS09835	COG2211	Major facilitator Superfamily
J9312_RS09840	COG3507	Belongs to the glycosyl hydrolase 43 family
J9312_RS09845	COG1940	carbohydrate kinase activity
J9312_RS09850	COG2115	Belongs to the xylose isomerase family
J9312_RS09855	COG1070	Carbohydrate kinase
J9312_RS09865	COG1525	nuclease
J9312_RS09870	COG2814	Major facilitator Superfamily
J9312_RS09875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J9312_RS09890	COG0756	dUTP diphosphatase activity
J9312_RS09930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J9312_RS09945	COG3832	glyoxalase III activity
J9312_RS09985	COG4195	phage-related replication protein
J9312_RS09995	COG0346	lactoylglutathione lyase activity
J9312_RS10005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J9312_RS10010	COG1388	LysM domain
J9312_RS10015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J9312_RS10020	COG4224	UPF0291 protein
J9312_RS10025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J9312_RS10035	COG3763	UPF0154 protein
J9312_RS10045	COG0785	Cytochrome C biogenesis protein
J9312_RS10050	COG2201	protein-glutamate methylesterase activity
J9312_RS10055	COG4846	Membrane protein involved in cytochrome C biogenesis
J9312_RS10065	COG0071	Belongs to the small heat shock protein (HSP20) family
J9312_RS10080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J9312_RS10085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_RS10105	COG0824	Thioesterase
J9312_RS10115	COG4841	protein insertion into membrane
J9312_RS10120	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J9312_RS10125	COG1832	CoA-binding protein
J9312_RS10130	COG0187	DNA topoisomerase II activity
J9312_RS10135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J9312_RS10150	COG1115	amino acid carrier protein
J9312_RS10155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J9312_RS10165	COG5520	Belongs to the glycosyl hydrolase 30 family
J9312_RS10175	COG2246	polysaccharide biosynthetic process
J9312_RS10180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J9312_RS10185	COG0586	Pfam SNARE associated Golgi protein
J9312_RS10190	COG2404	hydrolase activity, acting on ester bonds
J9312_RS10195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J9312_RS10200	COG1024	Enoyl-CoA hydratase
J9312_RS10205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J9312_RS10210	COG0511	ligase activity, forming carbon-carbon bonds
J9312_RS10215	COG0439	Biotin carboxylase
J9312_RS10220	COG0318	PFAM AMP-dependent synthetase and ligase
J9312_RS10225	COG1960	acyl-CoA dehydrogenase activity
J9312_RS10240	COG1649	PFAM Uncharacterised BCR, COG1649
J9312_RS10255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J9312_RS10260	COG2027	D-alanyl-D-alanine carboxypeptidase
J9312_RS10265	COG2017	converts alpha-aldose to the beta-anomer
J9312_RS10270	COG0534	Mate efflux family protein
J9312_RS10290	COG0582	viral genome integration into host DNA
J9312_RS10295	COG0166	Belongs to the GPI family
J9312_RS10300	COG0405	Gamma-glutamyltransferase
J9312_RS10305	COG0583	DNA-binding transcription factor activity
J9312_RS10310	COG0604	alcohol dehydrogenase
J9312_RS10315	COG0493	'glutamate synthase
J9312_RS10320	COG0067	glutamate synthase
J9312_RS10320	COG0070	glutamate synthase
J9312_RS10320	COG0069	glutamate synthase activity
J9312_RS10325	COG0583	DNA-binding transcription factor activity
J9312_RS10330	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J9312_RS10335	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J9312_RS10345	COG0300	oxidoreductase activity
J9312_RS10350	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
J9312_RS10360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_RS10375	COG1131	(ABC) transporter
J9312_RS10385	COG2814	Major facilitator Superfamily
J9312_RS10395	COG2323	membrane
J9312_RS10400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J9312_RS10405	COG3328	transposase activity
J9312_RS10435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9312_RS10455	COG5444	nuclease activity
J9312_RS10460	COG4282	regulation of fungal-type cell wall biogenesis
J9312_RS10465	COG1231	oxidoreductase activity
J9312_RS10470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J9312_RS10475	COG0662	Cupin 2, conserved barrel domain protein
J9312_RS10475	COG2207	Transcriptional regulator
J9312_RS10480	COG0456	acetyltransferase
J9312_RS10485	COG1309	transcriptional regulator
J9312_RS10490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9312_RS10495	COG3708	Transcriptional regulator
J9312_RS10500	COG2378	regulation of single-species biofilm formation
J9312_RS10510	COG0640	Transcriptional regulator
J9312_RS10515	COG0741	lytic transglycosylase activity
J9312_RS10520	COG2322	membrane
J9312_RS10535	COG1619	proteins homologs of microcin C7 resistance protein MccF
J9312_RS10540	COG3239	Fatty acid desaturase
J9312_RS10545	COG4585	Histidine kinase
J9312_RS10550	COG2197	response regulator
J9312_RS10555	COG1388	LysM domain
J9312_RS10555	COG3584	3D domain protein
J9312_RS10560	COG0514	ATP-dependent DNA helicase (RecQ)
J9312_RS10570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J9312_RS10575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J9312_RS10590	COG0071	Belongs to the small heat shock protein (HSP20) family
J9312_RS10615	COG1012	belongs to the aldehyde dehydrogenase family
J9312_RS10620	COG1657	PFAM Prenyltransferase squalene oxidase
J9312_RS10625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J9312_RS10630	COG0733	neurotransmitter:sodium symporter activity
J9312_RS10635	COG0385	Bile acid
J9312_RS10640	COG0508	dehydrogenase complex catalyzes the overall conversion of
J9312_RS10645	COG0567	Dehydrogenase, E1 component
J9312_RS10650	COG4548	von Willebrand factor, type A
J9312_RS10655	COG0714	Associated with various cellular activities
J9312_RS10660	COG2032	superoxide dismutase activity
J9312_RS10665	COG1388	LysM domain
J9312_RS10665	COG0791	NLP P60 protein
J9312_RS10670	COG1819	glycosyl
J9312_RS10675	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J9312_RS10680	COG0534	Mate efflux family protein
J9312_RS10685	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_RS10690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J9312_RS10695	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J9312_RS10705	COG2962	Rard protein
J9312_RS10720	COG2610	gluconate transmembrane transporter activity
J9312_RS10725	COG2610	gluconate transmembrane transporter activity
J9312_RS10730	COG1942	4-Oxalocrotonate Tautomerase
J9312_RS10735	COG1733	regulation of RNA biosynthetic process
J9312_RS10740	COG0778	Nitroreductase
J9312_RS10750	COG0793	Belongs to the peptidase S41A family
J9312_RS10750	COG3409	Peptidoglycan-binding domain 1 protein
J9312_RS10755	COG2226	methyltransferase
J9312_RS10765	COG1876	peptidase activity
J9312_RS10770	COG0813	purine-nucleoside phosphorylase activity
J9312_RS10785	COG0671	phosphoesterase, PA-phosphatase related
J9312_RS10805	COG4479	Belongs to the UPF0346 family
J9312_RS10815	COG1509	lysine 2,3-aminomutase activity
J9312_RS10820	COG0456	acetyltransferase
J9312_RS10825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J9312_RS10830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J9312_RS10835	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J9312_RS10840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J9312_RS10855	COG0456	acetyltransferase
J9312_RS10860	COG0463	Glycosyl transferase, family 2
J9312_RS10875	COG4641	Protein conserved in bacteria
J9312_RS10880	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
J9312_RS10885	COG1086	Polysaccharide biosynthesis protein
J9312_RS10890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J9312_RS10895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J9312_RS10900	COG1846	Transcriptional regulator
J9312_RS10905	COG0534	Mate efflux family protein
J9312_RS10915	COG4698	Protein conserved in bacteria
J9312_RS10920	COG2755	lipolytic protein G-D-S-L family
J9312_RS10925	COG1999	signal sequence binding
J9312_RS10935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J9312_RS10940	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J9312_RS10945	COG1272	protein, Hemolysin III
J9312_RS10950	COG0204	Acyl-transferase
J9312_RS10955	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J9312_RS10960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J9312_RS10970	COG2136	Putative SAM-dependent methyltransferase
J9312_RS10970	COG2521	methyltransferase
J9312_RS10980	COG0129	dihydroxy-acid dehydratase activity
J9312_RS10985	COG1413	lyase activity
J9312_RS10990	COG1418	mRNA catabolic process
J9312_RS10995	COG0386	Belongs to the glutathione peroxidase family
J9312_RS11000	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J9312_RS11005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J9312_RS11015	COG1278	Cold shock
J9312_RS11035	COG0328	RNA-DNA hybrid ribonuclease activity
J9312_RS11040	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J9312_RS11045	COG0328	RNA-DNA hybrid ribonuclease activity
J9312_RS11055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J9312_RS11070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J9312_RS11080	COG1755	Isoprenylcysteine carboxyl methyltransferase
J9312_RS11085	COG3424	synthase
J9312_RS11090	COG2233	PERMEase
J9312_RS11095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J9312_RS11100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J9312_RS11110	COG0800	Aldolase
J9312_RS11115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J9312_RS11120	COG1609	Transcriptional regulator
J9312_RS11125	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
J9312_RS11130	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS11135	COG1199	ATP-dependent helicase activity
J9312_RS11150	COG0116	Belongs to the methyltransferase superfamily
J9312_RS11165	COG4474	Belongs to the UPF0398 family
J9312_RS11185	COG1205	dead DEAH box helicase
J9312_RS11185	COG1111	helicase
J9312_RS11190	COG2190	(PTS) system
J9312_RS11195	COG0071	Belongs to the small heat shock protein (HSP20) family
J9312_RS11230	COG3331	DNA recombination
J9312_RS11235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J9312_RS11235	COG4499	WXG100 protein secretion system (Wss), protein YukC
J9312_RS11245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J9312_RS11250	COG3935	DnaD domain protein
J9312_RS11255	COG0017	Asparaginyl-tRNA synthetase
J9312_RS11260	COG0436	Aminotransferase
J9312_RS11265	COG5353	protein conserved in bacteria
J9312_RS11275	COG1199	ATP-dependent helicase activity
J9312_RS11275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J9312_RS11280	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J9312_RS11285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J9312_RS11290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J9312_RS11295	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J9312_RS11295	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J9312_RS11300	COG0617	tRNA 3'-terminal CCA addition
J9312_RS11305	COG0438	transferase activity, transferring glycosyl groups
J9312_RS11310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J9312_RS11315	COG1803	Methylglyoxal synthase
J9312_RS11320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J9312_RS11325	COG1694	Mazg nucleotide pyrophosphohydrolase
J9312_RS11330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_RS11340	COG4347	Protein of unknown function (DUF1405)
J9312_RS11345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J9312_RS11345	COG2010	Cytochrome c
J9312_RS11350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J9312_RS11355	COG0723	plastoquinol--plastocyanin reductase activity
J9312_RS11365	COG5582	Belongs to the UPF0302 family
J9312_RS11370	COG0457	Tetratricopeptide repeat
J9312_RS11375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J9312_RS11380	COG0287	Prephenate dehydrogenase
J9312_RS11390	COG0159	tryptophan synthase activity
J9312_RS11395	COG0133	tryptophan synthase activity
J9312_RS11400	COG0135	phosphoribosylanthranilate isomerase activity
J9312_RS11410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J9312_RS11415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J9312_RS11420	COG4401	Chorismate mutase type I
J9312_RS11425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J9312_RS11430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J9312_RS11435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J9312_RS11440	COG0105	UTP biosynthetic process
J9312_RS11445	COG0142	geranyltranstransferase activity
J9312_RS11450	COG2226	methyltransferase
J9312_RS11455	COG0142	geranyltranstransferase activity
J9312_RS11465	COG0302	gtp cyclohydrolase
J9312_RS11470	COG0776	regulation of translation
J9312_RS11475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J9312_RS11490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J9312_RS11495	COG1160	GTP binding
J9312_RS11525	COG1304	FMN binding
J9312_RS11530	COG0539	negative regulation of cytoplasmic translation
J9312_RS11535	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J9312_RS11545	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
J9312_RS11550	COG2959	enzyme of heme biosynthesis
J9312_RS11555	COG3773	Cell wall hydrolase
J9312_RS11555	COG3409	Peptidoglycan-binding domain 1 protein
J9312_RS11560	COG2339	peptidase activity
J9312_RS11565	COG0492	ferredoxin-NADP+ reductase activity
J9312_RS11570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J9312_RS11575	COG4862	establishment of competence for transformation
J9312_RS11580	COG1408	metallophosphoesterase
J9312_RS11590	COG1388	LysM domain
J9312_RS11595	COG1266	CAAX protease self-immunity
J9312_RS11600	COG0514	ATP-dependent DNA helicase (RecQ)
J9312_RS11605	COG4955	Helix-turn-helix domain
J9312_RS11610	COG1141	Ferredoxin
J9312_RS11615	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
J9312_RS11620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J9312_RS11625	COG0710	3-dehydroquinate dehydratase activity
J9312_RS11635	COG1595	DNA-templated transcription, initiation
J9312_RS11640	COG5002	protein histidine kinase activity
J9312_RS11645	COG0745	RESPONSE REGULATOR receiver
J9312_RS11650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J9312_RS11655	COG1333	cytochrome c biogenesis protein
J9312_RS11660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_RS11665	COG1187	pseudouridine synthase activity
J9312_RS11670	COG0700	Nucleoside recognition
J9312_RS11675	COG2715	membrane protein required for spore maturation
J9312_RS11680	COG1686	Belongs to the peptidase S11 family
J9312_RS11690	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J9312_RS11695	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J9312_RS11700	COG1547	Domain of unknown function (DUF309)
J9312_RS11705	COG0456	acetyltransferase
J9312_RS11710	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J9312_RS11715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J9312_RS11715	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J9312_RS11720	COG0307	riboflavin synthase, alpha
J9312_RS11725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J9312_RS11725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J9312_RS11735	COG0681	Belongs to the peptidase S26 family
J9312_RS11745	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
J9312_RS11790	COG3328	transposase activity
J9312_RS11795	COG3012	SEC-C Motif Domain Protein
J9312_RS11810	COG0457	Tetratricopeptide repeat
J9312_RS11820	COG3328	transposase activity
J9312_RS11870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J9312_RS11880	COG4086	secreted protein
J9312_RS11885	COG0019	diaminopimelate decarboxylase activity
J9312_RS11890	COG0697	spore germination
J9312_RS11905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J9312_RS11925	COG1191	sigma factor activity
J9312_RS11930	COG2172	sigma factor antagonist activity
J9312_RS11935	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_RS11940	COG1686	Belongs to the peptidase S11 family
J9312_RS11945	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J9312_RS11950	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J9312_RS11955	COG4974	Belongs to the 'phage' integrase family
J9312_RS11965	COG0735	belongs to the Fur family
J9312_RS11970	COG1300	Membrane
J9312_RS11980	COG0281	malic enzyme
J9312_RS11985	COG1757	Na H antiporter
J9312_RS11990	COG1027	Aspartate ammonia-lyase
J9312_RS11995	COG0252	asparaginase activity
J9312_RS12000	COG1396	sequence-specific DNA binding
J9312_RS12005	COG1379	DNA repair
J9312_RS12010	COG0494	nUDIX hydrolase
J9312_RS12020	COG0667	Aldo Keto reductase
J9312_RS12030	COG1073	alpha beta
J9312_RS12040	COG4918	Iron-sulphur cluster biosynthesis
J9312_RS12045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J9312_RS12045	COG0456	acetyltransferase
J9312_RS12050	COG2329	Antibiotic biosynthesis monooxygenase
J9312_RS12055	COG0456	acetyltransferase
J9312_RS12065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J9312_RS12075	COG2211	Major facilitator Superfamily
J9312_RS12085	COG0346	lactoylglutathione lyase activity
J9312_RS12090	COG1072	(Pantothenic acid kinase))
J9312_RS12095	COG3048	D-serine ammonia-lyase activity
J9312_RS12100	COG0300	oxidoreductase activity
J9312_RS12105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9312_RS12110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J9312_RS12115	COG4187	Peptidase family M20/M25/M40
J9312_RS12120	COG1902	pentaerythritol trinitrate reductase activity
J9312_RS12125	COG0596	Alpha beta hydrolase
J9312_RS12135	COG1234	tRNA 3'-trailer cleavage
J9312_RS12140	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J9312_RS12145	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J9312_RS12150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J9312_RS12160	COG0706	membrane insertase activity
J9312_RS12165	COG3361	conserved protein (COG2071)
J9312_RS12170	COG2195	Cleaves the N-terminal amino acid of tripeptides
J9312_RS12175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J9312_RS12180	COG0346	lactoylglutathione lyase activity
J9312_RS12190	COG1376	ErfK ybiS ycfS ynhG family protein
J9312_RS12195	COG4129	membrane
J9312_RS12200	COG1126	abc transporter atp-binding protein
J9312_RS12205	COG0765	amino acid transport
J9312_RS12210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J9312_RS12225	COG1597	lipid kinase activity
J9312_RS12230	COG2814	Major facilitator Superfamily
J9312_RS12235	COG4978	Transcriptional regulator
J9312_RS12235	COG0789	Transcriptional regulator
J9312_RS12240	COG0508	dehydrogenase complex catalyzes the overall conversion of
J9312_RS12245	COG0022	dehydrogenase e1 component
J9312_RS12250	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J9312_RS12255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J9312_RS12260	COG3426	butyrate kinase activity
J9312_RS12265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J9312_RS12270	COG0280	phosphate acetyltransferase
J9312_RS12275	COG3829	transcription factor binding
J9312_RS12275	COG3290	protein histidine kinase activity
J9312_RS12285	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J9312_RS12290	COG2079	MmgE PrpD family protein
J9312_RS12295	COG0372	Belongs to the citrate synthase family
J9312_RS12300	COG1960	acyl-CoA dehydrogenase activity
J9312_RS12305	COG1250	3-hydroxyacyl-CoA dehydrogenase
J9312_RS12310	COG0183	Belongs to the thiolase family
J9312_RS12315	COG0584	glycerophosphoryl diester phosphodiesterase
J9312_RS12320	COG0860	N-Acetylmuramoyl-L-alanine amidase
J9312_RS12335	COG1902	pentaerythritol trinitrate reductase activity
J9312_RS12340	COG0745	RESPONSE REGULATOR receiver
J9312_RS12345	COG0750	zinc metalloprotease
J9312_RS12350	COG0497	DNA recombination
J9312_RS12355	COG1438	arginine binding
J9312_RS12360	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J9312_RS12365	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J9312_RS12370	COG0142	geranyltranstransferase activity
J9312_RS12375	COG1722	exodeoxyribonuclease VII activity
J9312_RS12380	COG1570	exodeoxyribonuclease VII activity
J9312_RS12385	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J9312_RS12390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J9312_RS12395	COG1302	Protein conserved in bacteria
J9312_RS12400	COG0439	Biotin carboxylase
J9312_RS12405	COG0511	ligase activity, forming carbon-carbon bonds
J9312_RS12445	COG3854	ATPases associated with a variety of cellular activities
J9312_RS12455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J9312_RS12460	COG0006	proline dipeptidase activity
J9312_RS12465	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J9312_RS12475	COG3872	metal-dependent enzyme
J9312_RS12485	COG1752	Esterase of the alpha-beta hydrolase superfamily
J9312_RS12490	COG1321	iron dependent repressor
J9312_RS12495	COG0095	Lipoate-protein ligase
J9312_RS12500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J9312_RS12505	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J9312_RS12510	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J9312_RS12515	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J9312_RS12520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J9312_RS12535	COG1396	sequence-specific DNA binding
J9312_RS12545	COG0681	Belongs to the peptidase S26 family
J9312_RS12570	COG4940	Competence protein ComGF
J9312_RS12580	COG4970	Tfp pilus assembly protein FimT
J9312_RS12585	COG4537	Required for transformation and DNA binding
J9312_RS12590	COG1459	type II secretion system
J9312_RS12595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J9312_RS12600	COG0517	IMP dehydrogenase activity
J9312_RS12605	COG0598	Magnesium transport protein CorA
J9312_RS12610	COG1253	flavin adenine dinucleotide binding
J9312_RS12615	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_RS12625	COG1393	Belongs to the ArsC family
J9312_RS12635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9312_RS12645	COG0011	TIGRFAM Protein of
J9312_RS12655	COG2866	Carboxypeptidase
J9312_RS12660	COG1368	sulfuric ester hydrolase activity
J9312_RS12665	COG1940	carbohydrate kinase activity
J9312_RS12670	COG4483	Protein conserved in bacteria
J9312_RS12675	COG0705	Rhomboid family
J9312_RS12675	COG0457	Tetratricopeptide repeat
J9312_RS12685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J9312_RS12695	COG0438	transferase activity, transferring glycosyl groups
J9312_RS12710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J9312_RS12715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J9312_RS12720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J9312_RS12725	COG0581	inorganic phosphate transmembrane transporter activity
J9312_RS12730	COG0573	inorganic phosphate transmembrane transporter activity
J9312_RS12735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J9312_RS12740	COG0768	penicillin binding
J9312_RS12745	COG0477	Major facilitator Superfamily
J9312_RS12750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J9312_RS12755	COG2839	Protein conserved in bacteria
J9312_RS12760	COG5521	maltodextrose utilization protein MalA
J9312_RS12765	COG1388	LysM domain
J9312_RS12770	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J9312_RS12775	COG4709	membrane
J9312_RS12780	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
J9312_RS12785	COG0735	belongs to the Fur family
J9312_RS12790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_RS12800	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J9312_RS12805	COG0513	Belongs to the DEAD box helicase family
J9312_RS12815	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J9312_RS12820	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J9312_RS12825	COG2384	SAM-dependent methyltransferase
J9312_RS12830	COG2010	Cytochrome c
J9312_RS12835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J9312_RS12840	COG0358	DNA primase activity
J9312_RS12845	COG1671	Belongs to the UPF0178 family
J9312_RS12850	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J9312_RS12855	COG0517	IMP dehydrogenase activity
J9312_RS12860	COG0751	glycine-tRNA ligase activity
J9312_RS12865	COG0752	glycyl-tRNA synthetase alpha subunit
J9312_RS12870	COG1381	Involved in DNA repair and RecF pathway recombination
J9312_RS12880	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J9312_RS12885	COG0295	cytidine deaminase activity
J9312_RS12890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J9312_RS12895	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J9312_RS12900	COG1480	7TM receptor with intracellular HD hydrolase
J9312_RS12905	COG1702	phosphate starvation-inducible protein PhoH
J9312_RS12910	COG0561	phosphatase activity
J9312_RS12925	COG4864	UPF0365 protein
J9312_RS12930	COG1030	water channel activity
J9312_RS12935	COG1610	YqeY-like protein
J9312_RS12945	COG1283	sodium-dependent phosphate transmembrane transporter activity
J9312_RS12950	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J9312_RS12955	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J9312_RS12960	COG2264	protein methyltransferase activity
J9312_RS12965	COG0484	heat shock protein binding
J9312_RS12970	COG0443	Heat shock 70 kDa protein
J9312_RS12975	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J9312_RS12980	COG1420	regulation of RNA biosynthetic process
J9312_RS12985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J9312_RS12990	COG0481	GTPase activity
J9312_RS13000	COG0860	N-Acetylmuramoyl-L-alanine amidase
J9312_RS13005	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
J9312_RS13010	COG0268	Binds directly to 16S ribosomal RNA
J9312_RS13015	COG1466	dna polymerase III delta subunit
J9312_RS13030	COG2333	competence protein COMEC
J9312_RS13030	COG0658	competence protein
J9312_RS13035	COG2131	deaminase
J9312_RS13040	COG1596	polysaccharide export
J9312_RS13040	COG1555	photosystem II stabilization
J9312_RS13045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J9312_RS13050	COG2226	methyltransferase
J9312_RS13055	COG0799	negative regulation of ribosome biogenesis
J9312_RS13060	COG1713	HD superfamily hydrolase involved in NAD metabolism
J9312_RS13065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J9312_RS13070	COG1534	Rna-binding protein
J9312_RS13075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J9312_RS13080	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J9312_RS13085	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
J9312_RS13095	COG2755	lipolytic protein G-D-S-L family
J9312_RS13100	COG5632	N-Acetylmuramoyl-L-alanine amidase
J9312_RS13100	COG3409	Peptidoglycan-binding domain 1 protein
J9312_RS13105	COG0398	Pfam SNARE associated Golgi protein
J9312_RS13110	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
J9312_RS13120	COG3209	COG3209 Rhs family protein
J9312_RS13140	COG0114	fumarate hydratase activity
J9312_RS13145	COG0583	DNA-binding transcription factor activity
J9312_RS13160	COG0457	Tetratricopeptide repeat
J9312_RS13300	COG4978	Transcriptional regulator
J9312_RS13300	COG0789	Transcriptional regulator
J9312_RS13305	COG2814	Major facilitator Superfamily
J9312_RS13310	COG0456	acetyltransferase
J9312_RS13315	COG3328	transposase activity
J9312_RS13320	COG1253	flavin adenine dinucleotide binding
J9312_RS13330	COG0697	spore germination
J9312_RS13335	COG0583	DNA-binding transcription factor activity
J9312_RS13340	COG2072	flavoprotein involved in K transport
J9312_RS13345	COG1230	cation diffusion facilitator family transporter
J9312_RS13360	COG1114	Component of the transport system for branched-chain amino acids
J9312_RS13365	COG1687	branched-chain amino acid
J9312_RS13375	COG1522	sequence-specific DNA binding
J9312_RS13380	COG2732	(Barnase) inhibitor
J9312_RS13385	COG2124	cytochrome p450
J9312_RS13395	COG1335	isochorismatase
J9312_RS13415	COG2318	DinB family
J9312_RS13425	COG2070	2-Nitropropane dioxygenase
J9312_RS13430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J9312_RS13450	COG3443	Belongs to the bacterial solute-binding protein 9 family
J9312_RS13460	COG0667	Aldo Keto reductase
J9312_RS13465	COG3409	Peptidoglycan-binding domain 1 protein
J9312_RS13470	COG5566	PFAM Mor transcription activator
J9312_RS13475	COG0596	Alpha beta hydrolase
J9312_RS13480	COG4991	sh3 domain protein
J9312_RS13485	COG4991	sh3 domain protein
J9312_RS13495	COG0346	lactoylglutathione lyase activity
J9312_RS13505	COG5577	PFAM Coat F domain
J9312_RS13510	COG1063	alcohol dehydrogenase
J9312_RS13520	COG5577	PFAM Coat F domain
J9312_RS13525	COG0789	Transcriptional regulator
J9312_RS13535	COG1064	alcohol dehydrogenase
J9312_RS13540	COG0693	protein deglycase activity
J9312_RS13545	COG1621	beta-fructofuranosidase activity
J9312_RS13550	COG3716	PTS system mannose fructose sorbose family IID component
J9312_RS13555	COG3715	PTS system
J9312_RS13560	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_RS13565	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_RS13570	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J9312_RS13570	COG3933	PFAM sigma-54 factor interaction domain-containing protein
J9312_RS13580	COG1113	amino acid transport
J9312_RS13585	COG1280	lysine exporter protein (LysE YggA)
J9312_RS13590	COG1378	Sugar-specific transcriptional regulator TrmB
J9312_RS13595	COG1595	DNA-templated transcription, initiation
J9312_RS13605	COG2755	lipolytic protein G-D-S-L family
J9312_RS13605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J9312_RS13615	COG2124	cytochrome p450
J9312_RS13615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J9312_RS13620	COG1309	transcriptional regulator
J9312_RS13625	COG2226	methyltransferase
J9312_RS13640	COG2116	formate transmembrane transporter activity
J9312_RS13645	COG5609	conserved protein (DUF2294)
J9312_RS13650	COG3383	formate dehydrogenase (NAD+) activity
J9312_RS13655	COG2427	Protein of unknown function (DUF1641)
J9312_RS13665	COG0626	cystathionine gamma-synthase activity
J9312_RS13670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J9312_RS13675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J9312_RS13680	COG2226	methyltransferase
J9312_RS13695	COG0768	penicillin binding
J9312_RS13700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J9312_RS13705	COG0572	uridine kinase
J9312_RS13710	COG0826	peptidase U32
J9312_RS13715	COG0826	peptidase U32
J9312_RS13720	COG4122	O-methyltransferase activity
J9312_RS13725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J9312_RS13730	COG3906	Belongs to the UPF0473 family
J9312_RS13735	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J9312_RS13740	COG4472	Bacterial protein of unknown function (DUF965)
J9312_RS13745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J9312_RS13750	COG0628	permease
J9312_RS13755	COG1126	abc transporter atp-binding protein
J9312_RS13760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J9312_RS13765	COG0765	amino acid transport
J9312_RS13770	COG0765	amino acid transport
J9312_RS13785	COG3881	PFAM PRC-barrel domain
J9312_RS13790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J9312_RS13795	COG0457	Tetratricopeptide repeat
J9312_RS13800	COG0482	sulfurtransferase activity
J9312_RS13805	COG1104	cysteine desulfurase activity
J9312_RS13810	COG1959	2 iron, 2 sulfur cluster binding
J9312_RS13815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J9312_RS13820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J9312_RS13830	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J9312_RS13835	COG0124	histidyl-tRNA synthetase
J9312_RS13845	COG4991	sh3 domain protein
J9312_RS13845	COG3103	Sh3 type 3 domain protein
J9312_RS13845	COG0860	N-Acetylmuramoyl-L-alanine amidase
J9312_RS13850	COG1490	D-aminoacyl-tRNA deacylase activity
J9312_RS13855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J9312_RS13860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J9312_RS13865	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
J9312_RS13865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J9312_RS13870	COG5416	Lipopolysaccharide assembly protein A domain
J9312_RS13875	COG0490	domain, Protein
J9312_RS13880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J9312_RS13880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J9312_RS13890	COG2244	polysaccharide biosynthetic process
J9312_RS13895	COG2323	membrane
J9312_RS13905	COG1862	Preprotein translocase
J9312_RS13910	COG0343	queuine tRNA-ribosyltransferase activity
J9312_RS13915	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J9312_RS13925	COG2255	four-way junction helicase activity
J9312_RS13930	COG0632	four-way junction helicase activity
J9312_RS13940	COG2814	Major facilitator Superfamily
J9312_RS13945	COG0673	inositol 2-dehydrogenase activity
J9312_RS13950	COG2112	serine threonine protein kinase
J9312_RS13975	COG1115	amino acid carrier protein
J9312_RS13980	COG0217	transcriptional regulatory protein
J9312_RS13990	COG1388	LysM domain
J9312_RS13995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J9312_RS14000	COG0157	Belongs to the NadC ModD family
J9312_RS14005	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J9312_RS14010	COG1104	cysteine desulfurase activity
J9312_RS14015	COG1827	regulation of RNA biosynthetic process
J9312_RS14020	COG0077	Prephenate dehydratase
J9312_RS14025	COG4492	Belongs to the UPF0735 family
J9312_RS14030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J9312_RS14035	COG3290	protein histidine kinase activity
J9312_RS14045	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J9312_RS14050	COG2868	ribosomal protein
J9312_RS14055	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J9312_RS14060	COG1994	Peptidase M50
J9312_RS14065	COG0739	heme binding
J9312_RS14070	COG2894	cell division
J9312_RS14075	COG0850	regulation of cytokinetic process
J9312_RS14080	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J9312_RS14090	COG1077	Cell shape determining protein MreB Mrl
J9312_RS14095	COG2003	Belongs to the UPF0758 family
J9312_RS14100	COG0424	maF-like protein
J9312_RS14110	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J9312_RS14115	COG0285	dihydrofolate synthase activity
J9312_RS14120	COG0525	valine-tRNA ligase activity
J9312_RS14130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J9312_RS14135	COG1388	LysM domain
J9312_RS14140	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J9312_RS14145	COG0113	porphobilinogen synthase activity
J9312_RS14150	COG1587	Uroporphyrinogen-III synthase
J9312_RS14155	COG0181	hydroxymethylbilane synthase activity
J9312_RS14160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J9312_RS14165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J9312_RS14175	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J9312_RS14180	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J9312_RS14185	COG1067	ATP-dependent peptidase activity
J9312_RS14185	COG0470	DNA polymerase III
J9312_RS14190	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J9312_RS14195	COG0544	peptidyl-prolyl cis-trans isomerase activity
J9312_RS14200	COG0457	Tetratricopeptide repeat
J9312_RS14200	COG1477	protein flavinylation
J9312_RS14205	COG0066	3-isopropylmalate dehydratase activity
J9312_RS14210	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J9312_RS14215	COG0473	3-isopropylmalate dehydrogenase activity
J9312_RS14220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J9312_RS14225	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J9312_RS14230	COG0440	acetolactate synthase activity
J9312_RS14235	COG0028	Belongs to the TPP enzyme family
J9312_RS14245	COG0454	-acetyltransferase
J9312_RS14250	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
J9312_RS14265	COG0622	Phosphoesterase
J9312_RS14270	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J9312_RS14275	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J9312_RS14280	COG5401	PFAM Sporulation and spore germination
J9312_RS14285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J9312_RS14290	COG1846	Transcriptional regulator
J9312_RS14295	COG2197	response regulator
J9312_RS14300	COG0824	Thioesterase
J9312_RS14305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J9312_RS14310	COG1053	succinate dehydrogenase
J9312_RS14315	COG2009	succinate dehydrogenase
J9312_RS14320	COG1719	4-vinyl reductase, 4VR
J9312_RS14325	COG0527	aspartate kinase activity
J9312_RS14330	COG0322	excinuclease ABC activity
J9312_RS14335	COG3118	belongs to the thioredoxin family
J9312_RS14340	COG3534	alpha-L-arabinofuranosidase
J9312_RS14345	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
J9312_RS14350	COG2086	electron transfer activity
J9312_RS14355	COG1024	Enoyl-CoA hydratase
J9312_RS14360	COG1309	transcriptional regulator
J9312_RS14365	COG0318	PFAM AMP-dependent synthetase and ligase
J9312_RS14370	COG3766	membrane
J9312_RS14375	COG1193	negative regulation of DNA recombination
J9312_RS14380	COG1796	DNA polymerase
J9312_RS14380	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J9312_RS14385	COG1286	toxin biosynthetic process
J9312_RS14390	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
J9312_RS14395	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J9312_RS14400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J9312_RS14400	COG0072	phenylalanine-tRNA ligase activity
J9312_RS14405	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J9312_RS14415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J9312_RS14425	COG3835	regulator
J9312_RS14430	COG0277	FAD linked oxidase domain protein
J9312_RS14435	COG0247	lactate metabolic process
J9312_RS14440	COG0346	lactoylglutathione lyase activity
J9312_RS14450	COG1966	Carbon starvation protein
J9312_RS14455	COG3534	alpha-L-arabinofuranosidase
J9312_RS14460	COG0395	ABC-type sugar transport system, permease component
J9312_RS14465	COG1175	transmembrane transport
J9312_RS14470	COG1653	transport
J9312_RS14475	COG0371	Dehydrogenase
J9312_RS14480	COG0647	UMP catabolic process
J9312_RS14485	COG0235	Class ii aldolase
J9312_RS14490	COG1069	ribulokinase activity
J9312_RS14495	COG2160	L-arabinose isomerase activity
J9312_RS14500	COG3507	Belongs to the glycosyl hydrolase 43 family
J9312_RS14505	COG1363	Peptidase, m42
J9312_RS14515	COG3326	Membrane
J9312_RS14520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J9312_RS14525	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J9312_RS14530	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J9312_RS14540	COG1346	cytolysis
J9312_RS14545	COG1380	Effector of murein hydrolase LrgA
J9312_RS14550	COG3279	Response regulator of the LytR AlgR family
J9312_RS14555	COG3275	phosphorelay sensor kinase activity
J9312_RS14560	COG1011	Hydrolase
J9312_RS14565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J9312_RS14575	COG0398	Pfam SNARE associated Golgi protein
J9312_RS14580	COG1484	DNA-dependent DNA replication
J9312_RS14585	COG3611	Membrane attachment protein
J9312_RS14590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J9312_RS14595	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
J9312_RS14600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J9312_RS14615	COG0656	L-ascorbic acid biosynthetic process
J9312_RS14620	COG0237	dephospho-CoA kinase activity
J9312_RS14630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J9312_RS14635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J9312_RS14635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J9312_RS14640	COG5002	protein histidine kinase activity
J9312_RS14645	COG0745	RESPONSE REGULATOR receiver
J9312_RS14650	COG0039	L-malate dehydrogenase activity
J9312_RS14655	COG0538	isocitrate dehydrogenase activity
J9312_RS14660	COG0372	Belongs to the citrate synthase family
J9312_RS14665	COG2707	UPF0756 membrane protein
J9312_RS14670	COG0628	permease
J9312_RS14675	COG3030	protein affecting phage T7 exclusion by the F plasmid
J9312_RS14680	COG0469	pyruvate kinase activity
J9312_RS14685	COG0205	6-phosphofructokinase activity
J9312_RS14690	COG0825	malonyl-CoA metabolic process
J9312_RS14695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J9312_RS14700	COG0281	malic enzyme
J9312_RS14705	COG0587	DNA-directed DNA polymerase activity
J9312_RS14725	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J9312_RS14735	COG4109	DRTGG domain
J9312_RS14740	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
J9312_RS14745	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS14755	COG0165	Argininosuccinate lyase
J9312_RS14760	COG0137	argininosuccinate synthase activity
J9312_RS14765	COG0521	Mo-molybdopterin cofactor biosynthetic process
J9312_RS14770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J9312_RS14780	COG0827	DNA restriction-modification system
J9312_RS14785	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J9312_RS14790	COG3874	Sporulation protein YtfJ
J9312_RS14800	COG1714	RDD family
J9312_RS14805	COG0616	signal peptide processing
J9312_RS14810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J9312_RS14815	COG1574	metal-dependent hydrolase with the TIM-barrel fold
J9312_RS14820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J9312_RS14830	COG0301	tRNA thio-modification
J9312_RS14835	COG1104	cysteine desulfurase activity
J9312_RS14840	COG1114	Component of the transport system for branched-chain amino acids
J9312_RS14845	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
J9312_RS14850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J9312_RS14855	COG1309	transcriptional regulator
J9312_RS14860	COG1956	GAF domain-containing protein
J9312_RS14865	COG2203	Gaf domain
J9312_RS14865	COG2199	diguanylate cyclase activity
J9312_RS14870	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J9312_RS14880	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J9312_RS14885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J9312_RS14890	COG0454	-acetyltransferase
J9312_RS14895	COG0517	IMP dehydrogenase activity
J9312_RS14900	COG0123	including yeast histone deacetylase and acetoin utilization protein
J9312_RS14905	COG1360	Flagellar Motor Protein
J9312_RS14910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J9312_RS14915	COG1609	Transcriptional regulator
J9312_RS14920	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
J9312_RS14920	COG1605	Chorismate mutase
J9312_RS14925	COG3118	belongs to the thioredoxin family
J9312_RS14930	COG4980	gas vesicle protein
J9312_RS14935	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
J9312_RS14940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J9312_RS14945	COG1674	ftsk spoiiie
J9312_RS14950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J9312_RS14955	COG4848	Belongs to the UPF0354 family
J9312_RS14960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_RS14975	COG1363	Peptidase, m42
J9312_RS14980	COG5584	Small secreted protein
J9312_RS14985	COG0281	malic enzyme
J9312_RS14990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9312_RS14995	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J9312_RS15005	COG0510	thiamine kinase activity
J9312_RS15010	COG1523	belongs to the glycosyl hydrolase 13 family
J9312_RS15015	COG1597	lipid kinase activity
J9312_RS15025	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
J9312_RS15030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J9312_RS15035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J9312_RS15040	COG2252	PERMEase
J9312_RS15045	COG4473	ABC transporter
J9312_RS15050	COG1131	(ABC) transporter
J9312_RS15055	COG1349	DNA-binding transcription factor activity
J9312_RS15060	COG1187	pseudouridine synthase activity
J9312_RS15065	COG2244	polysaccharide biosynthetic process
J9312_RS15070	COG2081	HI0933 family
J9312_RS15075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J9312_RS15085	COG5578	integral membrane protein
J9312_RS15090	COG0673	inositol 2-dehydrogenase activity
J9312_RS15095	COG1653	transport
J9312_RS15100	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
J9312_RS15105	COG4209	transmembrane transport
J9312_RS15110	COG2207	Transcriptional regulator
J9312_RS15115	COG1653	transport
J9312_RS15120	COG0395	ABC-type sugar transport system, permease component
J9312_RS15125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J9312_RS15130	COG2124	cytochrome p450
J9312_RS15135	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J9312_RS15145	COG0156	8-amino-7-oxononanoate synthase activity
J9312_RS15150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J9312_RS15160	COG1073	alpha beta
J9312_RS15165	COG1609	Transcriptional regulator
J9312_RS15170	COG1653	transport
J9312_RS15175	COG1175	transmembrane transport
J9312_RS15180	COG0395	ABC-type sugar transport system, permease component
J9312_RS15185	COG1486	melibiose metabolic process
J9312_RS15190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J9312_RS15195	COG0495	leucyl-tRNA aminoacylation
J9312_RS15205	COG1366	Belongs to the anti-sigma-factor antagonist family
J9312_RS15205	COG2202	Pas domain
J9312_RS15210	COG2814	Major facilitator Superfamily
J9312_RS15220	COG0577	efflux transmembrane transporter activity
J9312_RS15225	COG1136	(ABC) transporter
J9312_RS15230	COG2205	protein histidine kinase activity
J9312_RS15235	COG0745	RESPONSE REGULATOR receiver
J9312_RS15240	COG0577	efflux transmembrane transporter activity
J9312_RS15245	COG1136	(ABC) transporter
J9312_RS15260	COG1131	(ABC) transporter
J9312_RS15265	COG1725	Transcriptional regulator
J9312_RS15280	COG1242	4 iron, 4 sulfur cluster binding
J9312_RS15285	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J9312_RS15295	COG2267	carboxylic ester hydrolase activity
J9312_RS15300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J9312_RS15305	COG1113	amino acid transport
J9312_RS15310	COG0367	asparagine synthase
J9312_RS15315	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J9312_RS15320	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J9312_RS15330	COG1506	peptidase
J9312_RS15335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J9312_RS15340	COG1116	anion transmembrane transporter activity
J9312_RS15345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J9312_RS15350	COG0494	nUDIX hydrolase
J9312_RS15355	COG4824	toxin secretion phage lysis holin
J9312_RS15360	COG0783	Belongs to the Dps family
J9312_RS15375	COG1854	S-ribosylhomocysteine lyase activity
J9312_RS15380	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J9312_RS15385	COG0288	reversible hydration of carbon dioxide
J9312_RS15390	COG0254	rRNA binding
J9312_RS15395	COG1271	oxidase subunit
J9312_RS15400	COG1294	oxidase, subunit
J9312_RS15410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J9312_RS15415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J9312_RS15415	COG1321	iron dependent repressor
J9312_RS15420	COG1121	(ABC) transporter
J9312_RS15425	COG0803	Belongs to the bacterial solute-binding protein 9 family
J9312_RS15430	COG4948	Mandelate Racemase Muconate Lactonizing
J9312_RS15435	COG0318	PFAM AMP-dependent synthetase and ligase
J9312_RS15440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J9312_RS15445	COG0596	Alpha beta hydrolase
J9312_RS15450	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J9312_RS15455	COG1169	isochorismate synthase
J9312_RS15460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J9312_RS15465	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J9312_RS15470	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J9312_RS15475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J9312_RS15480	COG0438	transferase activity, transferring glycosyl groups
J9312_RS15490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J9312_RS15495	COG0438	transferase activity, transferring glycosyl groups
J9312_RS15500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J9312_RS15505	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
J9312_RS15510	COG0058	SHG alpha-glucan phosphorylase activity
J9312_RS15515	COG0297	glycogen (starch) synthase activity
J9312_RS15520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J9312_RS15525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J9312_RS15530	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J9312_RS15655	COG3859	Proton-coupled thiamine transporter YuaJ
J9312_RS15660	COG1247	-acetyltransferase
J9312_RS15665	COG2268	Band 7 protein
J9312_RS15670	COG1585	Membrane protein implicated in regulation of membrane protease activity
J9312_RS15675	COG2318	DinB family
J9312_RS15685	COG1454	alcohol dehydrogenase
J9312_RS15690	COG1012	belongs to the aldehyde dehydrogenase family
J9312_RS15695	COG1510	regulation of RNA biosynthetic process
J9312_RS15710	COG0569	domain protein
J9312_RS15715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J9312_RS15720	COG4682	membrane
J9312_RS15725	COG1705	Flagellar rod assembly protein muramidase FlgJ
J9312_RS15730	COG0477	Major facilitator Superfamily
J9312_RS15735	COG5553	Cysteine dioxygenase type I
J9312_RS15745	COG1968	undecaprenyl-diphosphatase activity
J9312_RS15750	COG0628	permease
J9312_RS15755	COG0673	inositol 2-dehydrogenase activity
J9312_RS15765	COG3254	rhamnose metabolic process
J9312_RS15770	COG1070	Carbohydrate kinase
J9312_RS15775	COG1349	DNA-binding transcription factor activity
J9312_RS15780	COG3347	Dehydrogenase
J9312_RS15780	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS15790	COG0840	transmembrane signaling receptor activity
J9312_RS15795	COG0840	transmembrane signaling receptor activity
J9312_RS15800	COG0840	transmembrane signaling receptor activity
J9312_RS15815	COG0432	Pfam Uncharacterised protein family UPF0047
J9312_RS15825	COG0366	Alpha amylase catalytic
J9312_RS15830	COG1253	flavin adenine dinucleotide binding
J9312_RS15835	COG2738	Putative neutral zinc metallopeptidase
J9312_RS15850	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J9312_RS15865	COG0166	Belongs to the GPI family
J9312_RS15870	COG1979	alcohol dehydrogenase
J9312_RS15875	COG1979	alcohol dehydrogenase
J9312_RS15880	COG2155	Conserved Protein
J9312_RS15885	COG1098	S1 RNA binding domain
J9312_RS15890	COG0436	Aminotransferase
J9312_RS15895	COG1522	sequence-specific DNA binding
J9312_RS15900	COG2267	carboxylic ester hydrolase activity
J9312_RS15910	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J9312_RS15915	COG2205	protein histidine kinase activity
J9312_RS15925	COG5018	Exonuclease
J9312_RS15935	COG2814	Major facilitator Superfamily
J9312_RS15940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J9312_RS15945	COG3011	Protein conserved in bacteria
J9312_RS15955	COG3290	protein histidine kinase activity
J9312_RS15960	COG4565	transcriptional regulatory protein
J9312_RS15965	COG1744	ABC transporter substrate-binding protein PnrA-like
J9312_RS15970	COG3845	ABC transporter
J9312_RS15975	COG4603	Belongs to the binding-protein-dependent transport system permease family
J9312_RS15980	COG1079	Belongs to the binding-protein-dependent transport system permease family
J9312_RS15985	COG3493	citrate carrier protein
J9312_RS15995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J9312_RS15995	COG2111	Na H antiporter
J9312_RS16000	COG2111	Na H antiporter
J9312_RS16005	COG1006	Multisubunit Na H antiporter MnhC subunit
J9312_RS16010	COG0651	ATP synthesis coupled electron transport
J9312_RS16015	COG1863	multisubunit Na H antiporter MnhE subunit
J9312_RS16020	COG2212	antiporter activity
J9312_RS16025	COG1320	monovalent cation:proton antiporter activity
J9312_RS16030	COG2050	protein possibly involved in aromatic compounds catabolism
J9312_RS16035	COG2197	response regulator
J9312_RS16045	COG3328	transposase activity
J9312_RS16060	COG0142	geranyltranstransferase activity
J9312_RS16080	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J9312_RS16085	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J9312_RS16090	COG1335	isochorismatase
J9312_RS16095	COG5506	Protein of unknown function (DUF1694)
J9312_RS16110	COG0628	permease
J9312_RS16125	COG1418	mRNA catabolic process
J9312_RS16130	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS16140	COG1511	domain protein
J9312_RS16145	COG0433	COG0433 Predicted ATPase
J9312_RS16145	COG1674	ftsk spoiiie
J9312_RS16150	COG4499	WXG100 protein secretion system (Wss), protein YukC
J9312_RS16155	COG5417	Belongs to the EsaB family
J9312_RS16160	COG4842	Belongs to the WXG100 family
J9312_RS16165	COG2508	Transcriptional regulator
J9312_RS16165	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
J9312_RS16170	COG0686	Belongs to the AlaDH PNT family
J9312_RS16175	COG5634	Uncharacterized conserved protein (DUF2278)
J9312_RS16180	COG3251	PFAM MbtH domain protein
J9312_RS16185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J9312_RS16190	COG1535	isochorismatase
J9312_RS16190	COG3433	isochorismatase activity
J9312_RS16195	COG1021	2,3-dihydroxybenzoate-AMP ligase
J9312_RS16200	COG1169	isochorismate synthase
J9312_RS16205	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS16210	COG2819	hydrolase of the alpha beta superfamily
J9312_RS16215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J9312_RS16220	COG1268	BioY protein
J9312_RS16225	COG2056	Na+-H+ antiporter family
J9312_RS16230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J9312_RS16235	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
J9312_RS16240	COG3584	3D domain protein
J9312_RS16255	COG1252	NADH dehydrogenase
J9312_RS16260	COG0492	ferredoxin-NADP+ reductase activity
J9312_RS16270	COG0516	GMP reductase activity
J9312_RS16275	COG2808	Putative FMN-binding domain
J9312_RS16280	COG0456	acetyltransferase
J9312_RS16285	COG0316	Belongs to the HesB IscA family
J9312_RS16290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J9312_RS16295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J9312_RS16300	COG4844	belongs to the
J9312_RS16305	COG1252	NADH dehydrogenase
J9312_RS16310	COG4837	Protein of unknown function (DUF1462)
J9312_RS16315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J9312_RS16320	COG0823	Involved in the tonB-independent uptake of proteins
J9312_RS16320	COG4946	Tricorn protease homolog
J9312_RS16320	COG1506	peptidase
J9312_RS16325	COG0083	homoserine kinase activity
J9312_RS16330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J9312_RS16335	COG0460	homoserine dehydrogenase
J9312_RS16340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J9312_RS16345	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J9312_RS16350	COG0647	UMP catabolic process
J9312_RS16355	COG2445	Protein of unknown function DUF86
J9312_RS16360	COG4470	Protein conserved in bacteria
J9312_RS16370	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J9312_RS16375	COG0739	heme binding
J9312_RS16385	COG3377	Domain of unknown function (DUF1805)
J9312_RS16390	COG0737	Belongs to the 5'-nucleotidase family
J9312_RS16395	COG0730	response to heat
J9312_RS16400	COG1801	Protein of unknown function DUF72
J9312_RS16410	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J9312_RS16415	COG2508	Transcriptional regulator
J9312_RS16420	COG2233	PERMEase
J9312_RS16425	COG2233	PERMEase
J9312_RS16430	COG3648	Uricase
J9312_RS16430	COG3195	allantoin biosynthetic process
J9312_RS16435	COG2351	hydroxyisourate hydrolase activity
J9312_RS16445	COG2080	2 iron, 2 sulfur cluster binding
J9312_RS16450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J9312_RS16455	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
J9312_RS16460	COG2068	MobA-Related Protein
J9312_RS16465	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
J9312_RS16470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J9312_RS16475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J9312_RS16485	COG2356	endonuclease I
J9312_RS16490	COG3842	ATPase activity
J9312_RS16495	COG2188	Transcriptional regulator
J9312_RS16500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J9312_RS16505	COG0395	ABC-type sugar transport system, permease component
J9312_RS16510	COG1175	transmembrane transport
J9312_RS16515	COG1653	transport
J9312_RS16520	COG2222	sugar isomerase
J9312_RS16525	COG0322	excinuclease ABC activity
J9312_RS16530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J9312_RS16550	COG0346	lactoylglutathione lyase activity
J9312_RS16555	COG0640	Transcriptional regulator
J9312_RS16560	COG0719	Fe-S assembly protein
J9312_RS16565	COG0822	iron-sulfur transferase activity
J9312_RS16570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J9312_RS16575	COG0719	Fe-S assembly protein
J9312_RS16580	COG0396	ATPase activity
J9312_RS16590	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J9312_RS16595	COG1464	Belongs to the NlpA lipoprotein family
J9312_RS16600	COG2011	ABC-type metal ion transport system permease component
J9312_RS16605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J9312_RS16615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9312_RS16620	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J9312_RS16630	COG0509	glycine decarboxylation via glycine cleavage system
J9312_RS16635	COG1393	Belongs to the ArsC family
J9312_RS16640	COG1960	acyl-CoA dehydrogenase activity
J9312_RS16645	COG0183	Belongs to the thiolase family
J9312_RS16650	COG1024	Enoyl-CoA hydratase
J9312_RS16650	COG1250	3-hydroxyacyl-CoA dehydrogenase
J9312_RS16670	COG5577	PFAM Coat F domain
J9312_RS16675	COG1846	Transcriptional regulator
J9312_RS16680	COG0477	Major facilitator Superfamily
J9312_RS16685	COG1942	4-Oxalocrotonate Tautomerase
J9312_RS16690	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS16695	COG0583	DNA-binding transcription factor activity
J9312_RS16705	COG1120	ATPase activity
J9312_RS16720	COG3328	transposase activity
J9312_RS16730	COG1131	(ABC) transporter
J9312_RS16775	COG0783	Belongs to the Dps family
J9312_RS16780	COG3328	transposase activity
J9312_RS16785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9312_RS16790	COG0745	RESPONSE REGULATOR receiver
J9312_RS16795	COG2770	Histidine kinase
J9312_RS16795	COG2205	protein histidine kinase activity
J9312_RS16805	COG1309	transcriptional regulator
J9312_RS16810	COG0114	fumarate hydratase activity
J9312_RS16820	COG0697	spore germination
J9312_RS16825	COG0814	amino acid
J9312_RS16835	COG2197	response regulator
J9312_RS16840	COG4585	Histidine kinase
J9312_RS16845	COG4758	membrane
J9312_RS16850	COG3595	metallopeptidase activity
J9312_RS16855	COG1842	Phage shock protein A
J9312_RS16860	COG4758	membrane
J9312_RS16865	COG2814	Major facilitator Superfamily
J9312_RS16870	COG2096	Adenosyltransferase
J9312_RS16875	COG1120	ATPase activity
J9312_RS16880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_RS16885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J9312_RS16890	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS16895	COG3386	PFAM SMP-30 Gluconolaconase
J9312_RS16900	COG2205	protein histidine kinase activity
J9312_RS16905	COG0745	RESPONSE REGULATOR receiver
J9312_RS16915	COG1191	sigma factor activity
J9312_RS16925	COG2140	Oxalate decarboxylase
J9312_RS16935	COG0577	efflux transmembrane transporter activity
J9312_RS16940	COG1136	(ABC) transporter
J9312_RS16945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J9312_RS16950	COG1120	ATPase activity
J9312_RS16955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_RS16960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J9312_RS16965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J9312_RS16970	COG0531	amino acid
J9312_RS16980	COG1988	membrane-bound metal-dependent
J9312_RS16985	COG1368	sulfuric ester hydrolase activity
J9312_RS16990	COG1910	domain protein
J9312_RS16995	COG0725	ABC transporter, periplasmic molybdate-binding protein
J9312_RS17000	COG4149	molybdate abc transporter
J9312_RS17005	COG0656	L-ascorbic acid biosynthetic process
J9312_RS17015	COG0025	NhaP-type Na H and K H
J9312_RS17020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J9312_RS17025	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J9312_RS17030	COG3973	AAA domain
J9312_RS17040	COG2860	membrane
J9312_RS17045	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J9312_RS17050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J9312_RS17055	COG2217	Heavy metal translocating P-type atpase
J9312_RS17060	COG2217	Heavy metal translocating P-type atpase
J9312_RS17065	COG2608	mercury ion transmembrane transporter activity
J9312_RS17070	COG1937	Protein conserved in bacteria
J9312_RS17080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J9312_RS17085	COG1289	transmembrane transporter activity
J9312_RS17095	COG2076	Multidrug Resistance protein
J9312_RS17100	COG1309	transcriptional regulator
J9312_RS17105	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS17115	COG5444	nuclease activity
J9312_RS17130	COG5632	N-Acetylmuramoyl-L-alanine amidase
J9312_RS17130	COG3409	Peptidoglycan-binding domain 1 protein
J9312_RS17135	COG4824	toxin secretion phage lysis holin
J9312_RS17160	COG3942	CHAP domain
J9312_RS17160	COG1705	Flagellar rod assembly protein muramidase FlgJ
J9312_RS17425	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J9312_RS17430	COG0557	exoribonuclease II activity
J9312_RS17435	COG1647	Serine aminopeptidase, S33
J9312_RS17440	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J9312_RS17445	COG0596	Alpha beta hydrolase
J9312_RS17450	COG1476	TRANSCRIPTIONal
J9312_RS17455	COG1396	sequence-specific DNA binding
J9312_RS17460	COG1396	sequence-specific DNA binding
J9312_RS17465	COG1733	regulation of RNA biosynthetic process
J9312_RS17470	COG0840	transmembrane signaling receptor activity
J9312_RS17475	COG1174	glycine betaine transport
J9312_RS17480	COG1732	Glycine betaine
J9312_RS17485	COG1174	glycine betaine transport
J9312_RS17490	COG1125	glycine betaine transport
J9312_RS17490	COG0517	IMP dehydrogenase activity
J9312_RS17495	COG1510	regulation of RNA biosynthetic process
J9312_RS17500	COG1174	glycine betaine transport
J9312_RS17505	COG1732	Glycine betaine
J9312_RS17510	COG1174	glycine betaine transport
J9312_RS17515	COG1125	glycine betaine transport
J9312_RS17515	COG0517	IMP dehydrogenase activity
J9312_RS17520	COG1510	regulation of RNA biosynthetic process
J9312_RS17525	COG2095	MarC family integral membrane protein
J9312_RS17535	COG3064	Membrane
J9312_RS17540	COG4640	response to antibiotic
J9312_RS17545	COG0456	acetyltransferase
J9312_RS17550	COG0148	phosphopyruvate hydratase activity
J9312_RS17555	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J9312_RS17560	COG0149	triose-phosphate isomerase activity
J9312_RS17565	COG0126	phosphoglycerate kinase activity
J9312_RS17570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J9312_RS17575	COG2390	Transcriptional regulator
J9312_RS17580	COG2814	Major facilitator Superfamily
J9312_RS17585	COG1609	Transcriptional regulator
J9312_RS17590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J9312_RS17600	COG0583	DNA-binding transcription factor activity
J9312_RS17605	COG0697	spore germination
J9312_RS17610	COG1113	amino acid transport
J9312_RS17615	COG3858	chitin binding
J9312_RS17620	COG1556	Lactate utilization protein
J9312_RS17625	COG1139	Iron-sulfur cluster binding protein
J9312_RS17630	COG0247	lactate metabolic process
J9312_RS17635	COG2197	response regulator
J9312_RS17640	COG4585	Histidine kinase
J9312_RS17645	COG0842	Transport permease protein
J9312_RS17650	COG1131	(ABC) transporter
J9312_RS17660	COG0596	Alpha beta hydrolase
J9312_RS17665	COG2208	phosphoserine phosphatase activity
J9312_RS17670	COG3867	Arabinogalactan endo-beta-1,4-galactanase
J9312_RS17675	COG1874	Beta-galactosidase
J9312_RS17680	COG3833	ABC-type maltose transport systems, permease component
J9312_RS17685	COG1175	transmembrane transport
J9312_RS17690	COG2182	Extracellular solute-binding protein
J9312_RS17695	COG1609	Transcriptional regulator
J9312_RS17700	COG2186	Transcriptional regulator
J9312_RS17705	COG1620	l-lactate permease
J9312_RS17710	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J9312_RS17720	COG5039	Polysaccharide pyruvyl transferase
J9312_RS17725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J9312_RS17730	COG0110	maltose O-acetyltransferase activity
J9312_RS17735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J9312_RS17740	COG2244	polysaccharide biosynthetic process
J9312_RS17745	COG1216	Glycosyl transferase, family 2
J9312_RS17750	COG5039	Polysaccharide pyruvyl transferase
J9312_RS17755	COG1216	Glycosyl transferase, family 2
J9312_RS17765	COG0438	transferase activity, transferring glycosyl groups
J9312_RS17770	COG1215	transferase activity, transferring glycosyl groups
J9312_RS17775	COG0438	transferase activity, transferring glycosyl groups
J9312_RS17780	COG1086	Polysaccharide biosynthesis protein
J9312_RS17785	COG0489	protein tyrosine kinase activity
J9312_RS17790	COG3944	biosynthesis protein
J9312_RS17795	COG1396	sequence-specific DNA binding
J9312_RS17800	COG2272	Belongs to the type-B carboxylesterase lipase family
J9312_RS17810	COG3479	Phenolic acid decarboxylase
J9312_RS17820	COG1794	racemase activity, acting on amino acids and derivatives
J9312_RS17830	COG1621	beta-fructofuranosidase activity
J9312_RS17835	COG1621	beta-fructofuranosidase activity
J9312_RS17840	COG0531	amino acid
J9312_RS17845	COG1309	transcriptional regulator
J9312_RS17850	COG2076	Multidrug Resistance protein
J9312_RS17855	COG2076	Multidrug Resistance protein
J9312_RS17875	COG1674	ftsk spoiiie
J9312_RS17895	COG5632	N-Acetylmuramoyl-L-alanine amidase
J9312_RS17895	COG3409	Peptidoglycan-binding domain 1 protein
J9312_RS17895	COG1388	LysM domain
J9312_RS17930	COG1705	Flagellar rod assembly protein muramidase FlgJ
J9312_RS18010	COG0582	viral genome integration into host DNA
J9312_RS18120	COG4974	Belongs to the 'phage' integrase family
J9312_RS18130	COG0740	serine-type endopeptidase activity
J9312_RS18135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J9312_RS18140	COG0366	Alpha amylase catalytic
J9312_RS18145	COG1554	hydrolase, family 65, central catalytic
J9312_RS18155	COG3833	ABC-type maltose transport systems, permease component
J9312_RS18160	COG1175	transmembrane transport
J9312_RS18165	COG2182	Extracellular solute-binding protein
J9312_RS18175	COG1609	Transcriptional regulator
J9312_RS18180	COG1611	Belongs to the LOG family
J9312_RS18190	COG0659	secondary active sulfate transmembrane transporter activity
J9312_RS18195	COG0288	reversible hydration of carbon dioxide
J9312_RS18200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J9312_RS18205	COG0577	efflux transmembrane transporter activity
J9312_RS18210	COG1136	(ABC) transporter
J9312_RS18215	COG5002	protein histidine kinase activity
J9312_RS18220	COG0745	RESPONSE REGULATOR receiver
J9312_RS18230	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J9312_RS18235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_RS18240	COG1481	regulation of sporulation
J9312_RS18245	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J9312_RS18250	COG1660	Displays ATPase and GTPase activities
J9312_RS18255	COG1051	belongs to the nudix hydrolase family
J9312_RS18260	COG0492	ferredoxin-NADP+ reductase activity
J9312_RS18265	COG3883	PFAM NLP P60 protein
J9312_RS18265	COG0791	NLP P60 protein
J9312_RS18270	COG0457	Tetratricopeptide repeat
J9312_RS18275	COG1132	(ABC) transporter
J9312_RS18295	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J9312_RS18295	COG0140	phosphoribosyl-ATP diphosphatase activity
J9312_RS18300	COG0107	imidazoleglycerol-phosphate synthase activity
J9312_RS18305	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J9312_RS18310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J9312_RS18315	COG0131	Imidazoleglycerol-phosphate dehydratase
J9312_RS18320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J9312_RS18325	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J9312_RS18330	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
J9312_RS18335	COG4990	cell redox homeostasis
J9312_RS18340	COG5297	Belongs to the glycosyl hydrolase family 6
J9312_RS18345	COG0110	maltose O-acetyltransferase activity
J9312_RS18350	COG0546	phosphoglycolate phosphatase activity
J9312_RS18355	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J9312_RS18360	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J9312_RS18365	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J9312_RS18370	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J9312_RS18375	COG0363	glucosamine-6-phosphate deaminase activity
J9312_RS18380	COG2188	Transcriptional regulator
J9312_RS18385	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J9312_RS18390	COG1950	PFAM Membrane protein of
J9312_RS18395	COG1983	PspC domain protein
J9312_RS18400	COG3595	metallopeptidase activity
J9312_RS18415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J9312_RS18420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J9312_RS18425	COG0556	nucleotide-excision repair
J9312_RS18430	COG4897	Protein conserved in bacteria
J9312_RS18435	COG3848	Pyruvate phosphate dikinase
J9312_RS18435	COG0574	Belongs to the PEP-utilizing enzyme family
J9312_RS18440	COG1309	transcriptional regulator
J9312_RS18445	COG2814	Major facilitator Superfamily
J9312_RS18450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9312_RS18460	COG0793	Belongs to the peptidase S41A family
J9312_RS18460	COG3409	Peptidoglycan-binding domain 1 protein
J9312_RS18465	COG2177	Part of the ABC transporter FtsEX involved in
J9312_RS18470	COG2884	Cell division ATP-binding protein ftsE
J9312_RS18475	COG2010	Cytochrome c
J9312_RS18480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_RS18490	COG0653	protein targeting
J9312_RS18495	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J9312_RS18510	COG1516	flagellar protein fliS
J9312_RS18515	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J9312_RS18520	COG1334	flagellar protein FlaG
J9312_RS18525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J9312_RS18530	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
J9312_RS18535	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
J9312_RS18545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J9312_RS18550	COG1256	bacterial-type flagellum assembly
J9312_RS18550	COG4786	Flagellar basal body rod
J9312_RS18555	COG3418	PFAM FlgN family protein
J9312_RS18560	COG2747	anti-sigma28 factor FlgM
J9312_RS18570	COG1040	competence protein
J9312_RS18580	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
J9312_RS18585	COG1307	EDD domain protein, DegV family
J9312_RS18590	COG2197	response regulator
J9312_RS18595	COG4585	Histidine kinase
J9312_RS18600	COG1739	Uncharacterized protein family UPF0029
J9312_RS18635	COG1131	(ABC) transporter
J9312_RS18645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J9312_RS18650	COG0438	transferase activity, transferring glycosyl groups
J9312_RS18655	COG1215	transferase activity, transferring glycosyl groups
J9312_RS18660	COG3206	protein involved in exopolysaccharide biosynthesis
J9312_RS18665	COG3307	-O-antigen
J9312_RS18670	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J9312_RS18675	COG0438	transferase activity, transferring glycosyl groups
J9312_RS18675	COG0297	glycogen (starch) synthase activity
J9312_RS18680	COG2244	polysaccharide biosynthetic process
J9312_RS18690	COG0860	N-Acetylmuramoyl-L-alanine amidase
J9312_RS18690	COG2247	cell wall binding repeat
J9312_RS18695	COG2385	sporulation resulting in formation of a cellular spore
J9312_RS18695	COG2247	cell wall binding repeat
J9312_RS18710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J9312_RS18715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J9312_RS18730	COG1682	transport, permease protein
J9312_RS18740	COG0463	Glycosyl transferase, family 2
J9312_RS18740	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J9312_RS18745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J9312_RS18750	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J9312_RS18755	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J9312_RS18760	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J9312_RS18765	COG4193	domain, Protein
J9312_RS18770	COG1482	cell wall glycoprotein biosynthetic process
J9312_RS18775	COG0697	spore germination
J9312_RS18780	COG0814	amino acid
J9312_RS18795	COG1316	TRANSCRIPTIONal
J9312_RS18800	COG0561	phosphatase activity
J9312_RS18805	COG0791	NLP P60 protein
J9312_RS18815	COG2843	Capsule synthesis protein
J9312_RS18825	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J9312_RS18830	COG1609	Transcriptional regulator
J9312_RS18835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J9312_RS18840	COG1869	D-ribose catabolic process
J9312_RS18845	COG1129	ABC transporter
J9312_RS18850	COG1172	Belongs to the binding-protein-dependent transport system permease family
J9312_RS18860	COG3103	Sh3 type 3 domain protein
J9312_RS18870	COG2249	NAD(P)H dehydrogenase (quinone) activity
J9312_RS18875	COG3527	Alpha-acetolactate decarboxylase
J9312_RS18880	COG0028	Belongs to the TPP enzyme family
J9312_RS18885	COG0583	DNA-binding transcription factor activity
J9312_RS18890	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J9312_RS18905	COG5337	Spore coat protein CotH
J9312_RS18915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J9312_RS18925	COG0405	Gamma-glutamyltransferase
J9312_RS18930	COG1522	sequence-specific DNA binding
J9312_RS18935	COG2059	Chromate
J9312_RS18940	COG2059	Chromate
J9312_RS18955	COG0583	DNA-binding transcription factor activity
J9312_RS19010	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J9312_RS19015	COG4464	protein tyrosine phosphatase activity
J9312_RS19020	COG0489	protein tyrosine kinase activity
J9312_RS19025	COG3944	biosynthesis protein
J9312_RS19035	COG4715	Zinc finger, swim domain protein
J9312_RS19040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J9312_RS19045	COG0561	phosphatase activity
J9312_RS19050	COG1349	DNA-binding transcription factor activity
J9312_RS19055	COG0629	single-stranded DNA binding
J9312_RS19080	COG0745	RESPONSE REGULATOR receiver
J9312_RS19080	COG2972	Histidine kinase
J9312_RS19085	COG1970	mechanosensitive ion channel activity
J9312_RS19090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J9312_RS19095	COG0457	Tetratricopeptide repeat
J9312_RS19100	COG4786	Flagellar basal body rod
J9312_RS19105	COG4786	Flagellar basal body rod
J9312_RS19110	COG1077	Cell shape determining protein MreB Mrl
J9312_RS19115	COG1609	Transcriptional regulator
J9312_RS19125	COG1846	Transcriptional regulator
J9312_RS19130	COG2814	Major facilitator Superfamily
J9312_RS19135	COG3420	alginic acid biosynthetic process
J9312_RS19140	COG1953	Uracil, thiamine, allantoin
J9312_RS19145	COG0477	Major facilitator Superfamily
J9312_RS19150	COG1335	isochorismatase
J9312_RS19160	COG0004	ammonium transporteR
J9312_RS19165	COG0347	Belongs to the P(II) protein family
J9312_RS19170	COG0671	phosphoesterase, PA-phosphatase related
J9312_RS19180	COG0739	heme binding
J9312_RS19185	COG1247	-acetyltransferase
J9312_RS19195	COG2089	acid synthase
J9312_RS19205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J9312_RS19210	COG0789	Transcriptional regulator
J9312_RS19225	COG1959	2 iron, 2 sulfur cluster binding
J9312_RS19230	COG0804	urea catabolic process
J9312_RS19235	COG0832	Belongs to the urease beta subunit family
J9312_RS19240	COG0831	urea catabolic process
J9312_RS19255	COG3237	CsbD-like
J9312_RS19260	COG1994	Peptidase M50
J9312_RS19265	COG0457	Tetratricopeptide repeat
J9312_RS19270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J9312_RS19275	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J9312_RS19285	COG2304	oxidoreductase activity
J9312_RS19295	COG2304	oxidoreductase activity
J9312_RS19300	COG2385	sporulation resulting in formation of a cellular spore
J9312_RS19305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J9312_RS19315	COG4836	Membrane
J9312_RS19325	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J9312_RS19330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J9312_RS19335	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J9312_RS19340	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J9312_RS19345	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J9312_RS19350	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J9312_RS19360	COG0356	it plays a direct role in the translocation of protons across the membrane
J9312_RS19370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J9312_RS19375	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J9312_RS19380	COG4475	Protein of unknown function (DUF436)
J9312_RS19385	COG0698	ribose 5-phosphate isomerase
J9312_RS19390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J9312_RS19395	COG1971	Probably functions as a manganese efflux pump
J9312_RS19400	COG0009	L-threonylcarbamoyladenylate synthase
J9312_RS19405	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J9312_RS19425	COG2890	protein-(glutamine-N5) methyltransferase activity
J9312_RS19430	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J9312_RS19435	COG0346	lactoylglutathione lyase activity
J9312_RS19440	COG0789	Transcriptional regulator
J9312_RS19445	COG0679	Auxin Efflux Carrier
J9312_RS19450	COG0281	malic enzyme
J9312_RS19455	COG1435	thymidine kinase activity
J9312_RS19465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J9312_RS19475	COG1494	fructose-1,6-bisphosphatase
J9312_RS19480	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J9312_RS19485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J9312_RS19490	COG0191	fructose-bisphosphate aldolase activity
J9312_RS19495	COG2204	response regulator
J9312_RS19500	COG4821	SIS domain
J9312_RS19510	COG0504	CTP synthase activity
J9312_RS19515	COG3343	RNA polymerase activity
J9312_RS19520	COG1960	acyl-CoA dehydrogenase activity
J9312_RS19525	COG2181	nitrate reductase activity
J9312_RS19525	COG0247	lactate metabolic process
J9312_RS19530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J9312_RS19535	COG4294	response to UV
J9312_RS19545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J9312_RS19555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J9312_RS19565	COG2181	nitrate reductase activity
J9312_RS19570	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
J9312_RS19575	COG1140	nitrate reductase beta subunit
J9312_RS19580	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
J9312_RS19585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J9312_RS19595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J9312_RS19600	COG2223	nitrite transmembrane transporter activity
J9312_RS19605	COG0018	arginyl-trna synthetase
J9312_RS19610	COG4506	Protein conserved in bacteria
J9312_RS19625	COG0535	radical SAM domain protein
J9312_RS19635	COG1131	(ABC) transporter
J9312_RS19640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J9312_RS19645	COG0612	Peptidase, M16
J9312_RS19650	COG0612	Peptidase, M16
J9312_RS19660	COG3391	amine dehydrogenase activity
J9312_RS19665	COG3391	amine dehydrogenase activity
J9312_RS19670	COG0457	Tetratricopeptide repeat
J9312_RS19685	COG0010	Belongs to the arginase family
J9312_RS19690	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J9312_RS19695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J9312_RS19705	COG1994	Peptidase M50
J9312_RS19710	COG1942	4-Oxalocrotonate Tautomerase
J9312_RS19715	COG1846	Transcriptional regulator
J9312_RS19720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J9312_RS19725	COG0477	Major facilitator Superfamily
J9312_RS19730	COG1959	2 iron, 2 sulfur cluster binding
J9312_RS19735	COG3465	dGTPase activity
J9312_RS19740	COG1078	dGTPase activity
J9312_RS19745	COG4844	belongs to the
J9312_RS19755	COG0697	spore germination
J9312_RS19760	COG0095	Lipoate-protein ligase
J9312_RS19765	COG0583	DNA-binding transcription factor activity
J9312_RS19775	COG0280	phosphate acetyltransferase
J9312_RS19780	COG3253	May function as heme-dependent peroxidase
J9312_RS19785	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS19790	COG0436	Aminotransferase
J9312_RS19795	COG2814	Major facilitator Superfamily
J9312_RS19800	COG0151	Belongs to the GarS family
J9312_RS19805	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS19810	COG1917	Cupin 2, conserved barrel domain protein
J9312_RS19815	COG0077	Prephenate dehydratase
J9312_RS19820	COG2814	Major facilitator Superfamily
J9312_RS19825	COG0833	amino acid
J9312_RS19830	COG4187	Peptidase family M20/M25/M40
J9312_RS19835	COG1012	belongs to the aldehyde dehydrogenase family
J9312_RS19840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J9312_RS19850	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
J9312_RS19855	COG1091	dTDP-4-dehydrorhamnose reductase activity
J9312_RS19860	COG1088	dTDP-glucose 4,6-dehydratase activity
J9312_RS19865	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J9312_RS19870	COG3980	spore coat polysaccharide biosynthesis protein
J9312_RS19875	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
J9312_RS19880	COG2089	acid synthase
J9312_RS19885	COG0456	acetyltransferase
J9312_RS19890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J9312_RS19895	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J9312_RS19900	COG0463	Glycosyl transferase, family 2
J9312_RS19915	COG2363	Small membrane protein
J9312_RS19920	COG2233	PERMEase
J9312_RS19930	COG1012	belongs to the aldehyde dehydrogenase family
J9312_RS19935	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J9312_RS19940	COG1216	Glycosyl transferase, family 2
J9312_RS19955	COG1695	Transcriptional regulator
J9312_RS19960	COG0351	phosphomethylpyrimidine kinase
J9312_RS19970	COG1621	beta-fructofuranosidase activity
J9312_RS19975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_RS19975	COG1263	PTS System
J9312_RS19980	COG2116	formate transmembrane transporter activity
J9312_RS19985	COG3711	transcriptional antiterminator
J9312_RS19995	COG1404	Belongs to the peptidase S8 family
J9312_RS20000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J9312_RS20005	COG0778	Nitroreductase
J9312_RS20010	COG0772	Belongs to the SEDS family
J9312_RS20025	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J9312_RS20030	COG1845	cytochrome c oxidase, subunit III
J9312_RS20035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J9312_RS20040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J9312_RS20045	COG2261	transglycosylase associated protein
J9312_RS20050	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
J9312_RS20055	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J9312_RS20060	COG2246	polysaccharide biosynthetic process
J9312_RS20065	COG1309	transcriptional regulator
J9312_RS20075	COG3162	membrane
J9312_RS20080	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J9312_RS20085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J9312_RS20090	COG2837	iron assimilation
J9312_RS20095	COG2822	iron ion transport
J9312_RS20100	COG0672	)-iron permease
J9312_RS20105	COG0352	thiamine-phosphate diphosphorylase activity
J9312_RS20110	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J9312_RS20115	COG0583	DNA-binding transcription factor activity
J9312_RS20120	COG1380	Effector of murein hydrolase LrgA
J9312_RS20125	COG1346	cytolysis
J9312_RS20130	COG2814	Major facilitator Superfamily
J9312_RS20135	COG4895	conserved protein (DUF2196)
J9312_RS20140	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J9312_RS20145	COG0346	lactoylglutathione lyase activity
J9312_RS20160	COG1404	Belongs to the peptidase S8 family
J9312_RS20165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J9312_RS20165	COG1263	PTS System
J9312_RS20170	COG3711	transcriptional antiterminator
J9312_RS20175	COG1442	glycosyl transferase family 8
J9312_RS20180	COG5522	Integral membrane protein (intg_mem_TP0381)
J9312_RS20185	COG1846	Transcriptional regulator
J9312_RS20190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J9312_RS20195	COG2234	aminopeptidase activity
J9312_RS20200	COG2357	RelA SpoT domain protein
J9312_RS20210	COG1575	Belongs to the MenA family. Type 1 subfamily
J9312_RS20225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J9312_RS20230	COG1696	Membrane protein involved in D-alanine export
J9312_RS20235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J9312_RS20240	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
J9312_RS20245	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
J9312_RS20250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J9312_RS20255	COG1486	melibiose metabolic process
J9312_RS20260	COG1447	Phosphotransferase system cellobiose-specific component IIA
J9312_RS20265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J9312_RS20270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J9312_RS20275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9312_RS20275	COG3711	transcriptional antiterminator
J9312_RS20285	COG2094	Belongs to the DNA glycosylase MPG family
J9312_RS20290	COG0753	catalase activity
J9312_RS20295	COG2814	Major facilitator Superfamily
J9312_RS20300	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J9312_RS20305	COG1131	(ABC) transporter
J9312_RS20325	COG1595	DNA-templated transcription, initiation
J9312_RS20330	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J9312_RS20335	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J9312_RS20340	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J9312_RS20345	COG4988	ABC transporter
J9312_RS20350	COG1294	oxidase, subunit
J9312_RS20355	COG1271	oxidase subunit
J9312_RS20360	COG3493	citrate carrier protein
J9312_RS20365	COG0501	Belongs to the peptidase M48B family
J9312_RS20375	COG0726	polysaccharide deacetylase
J9312_RS20385	COG3842	ATPase activity
J9312_RS20390	COG2508	Transcriptional regulator
J9312_RS20395	COG1012	belongs to the aldehyde dehydrogenase family
J9312_RS20400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J9312_RS20405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J9312_RS20415	COG4585	Histidine kinase
J9312_RS20420	COG2197	response regulator
J9312_RS20425	COG2195	Cleaves the N-terminal amino acid of tripeptides
J9312_RS20440	COG4894	glucomannan catabolic process
J9312_RS20445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J9312_RS20450	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J9312_RS20455	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS20460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J9312_RS20465	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J9312_RS20470	COG2610	gluconate transmembrane transporter activity
J9312_RS20475	COG0500	methyltransferase
J9312_RS20480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J9312_RS20495	COG0693	protein deglycase activity
J9312_RS20495	COG0753	catalase activity
J9312_RS20500	COG2851	Citrate transporter
J9312_RS20505	COG2273	Hydrolase Family 16
J9312_RS20510	COG3711	transcriptional antiterminator
J9312_RS20520	COG2270	Major facilitator Superfamily
J9312_RS20525	COG0513	Belongs to the DEAD box helicase family
J9312_RS20530	COG2755	lipolytic protein G-D-S-L family
J9312_RS20530	COG3401	FG-GAP repeat protein
J9312_RS20650	COG0697	spore germination
J9312_RS20655	COG0589	response to stress
J9312_RS20675	COG5444	nuclease activity
J9312_RS20710	COG3507	Belongs to the glycosyl hydrolase 43 family
J9312_RS20720	COG1228	amidohydrolase
J9312_RS20725	COG0010	Belongs to the arginase family
J9312_RS20730	COG0833	amino acid
J9312_RS20735	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J9312_RS20740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J9312_RS20745	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J9312_RS20750	COG2390	Transcriptional regulator
J9312_RS20760	COG3192	ethanolamine utilization protein
J9312_RS20765	COG2079	MmgE PrpD family protein
J9312_RS20770	COG1473	amidohydrolase
J9312_RS20775	COG1126	abc transporter atp-binding protein
J9312_RS20780	COG0765	amino acid transport
J9312_RS20785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J9312_RS20790	COG0456	acetyltransferase
J9312_RS20795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J9312_RS20800	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
J9312_RS20805	COG0561	phosphatase activity
J9312_RS20835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J9312_RS20840	COG5294	Protein conserved in bacteria
J9312_RS20845	COG0577	efflux transmembrane transporter activity
J9312_RS20850	COG1136	(ABC) transporter
J9312_RS20855	COG2205	protein histidine kinase activity
J9312_RS20865	COG0191	fructose-bisphosphate aldolase activity
J9312_RS20870	COG1082	Xylose isomerase domain protein TIM barrel
J9312_RS20875	COG1082	Xylose isomerase domain protein TIM barrel
J9312_RS20880	COG0673	inositol 2-dehydrogenase activity
J9312_RS20890	COG1082	Xylose isomerase domain protein TIM barrel
J9312_RS20895	COG3962	Belongs to the TPP enzyme family
J9312_RS20900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J9312_RS20915	COG1349	DNA-binding transcription factor activity
J9312_RS20920	COG0667	Aldo Keto reductase
J9312_RS20935	COG2814	Major facilitator Superfamily
J9312_RS20940	COG0326	Molecular chaperone. Has ATPase activity
J9312_RS20990	COG1309	transcriptional regulator
J9312_RS20995	COG1012	belongs to the aldehyde dehydrogenase family
J9312_RS21000	COG1714	RDD family
J9312_RS21010	COG1714	RDD family
J9312_RS21015	COG2311	Membrane
J9312_RS21020	COG1917	Cupin 2, conserved barrel domain protein
J9312_RS21025	COG1309	transcriptional regulator
J9312_RS21030	COG1028	Short-chain dehydrogenase reductase Sdr
J9312_RS21035	COG1846	Transcriptional regulator
J9312_RS21040	COG1380	Effector of murein hydrolase LrgA
J9312_RS21045	COG1346	cytolysis
J9312_RS21050	COG5039	Polysaccharide pyruvyl transferase
J9312_RS21055	COG1929	Belongs to the glycerate kinase type-1 family
J9312_RS21060	COG1802	Transcriptional regulator
J9312_RS21065	COG1070	Carbohydrate kinase
J9312_RS21070	COG2610	gluconate transmembrane transporter activity
J9312_RS21075	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J9312_RS21080	COG0450	alkyl hydroperoxide reductase
J9312_RS21085	COG3634	alkyl hydroperoxide reductase activity
J9312_RS21090	COG2723	6-phospho-beta-galactosidase activity
J9312_RS21095	COG2190	(PTS) system
J9312_RS21105	COG2188	Transcriptional regulator
J9312_RS21120	COG1131	(ABC) transporter
J9312_RS21125	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
J9312_RS21135	COG0071	Belongs to the small heat shock protein (HSP20) family
J9312_RS21170	COG0210	DNA helicase
J9312_RS21200	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J9312_RS21215	COG1063	alcohol dehydrogenase
J9312_RS21235	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
J9312_RS21240	COG0456	acetyltransferase
J9312_RS21245	COG0457	Tetratricopeptide repeat
J9312_RS21255	COG0010	Belongs to the arginase family
J9312_RS21260	COG0833	amino acid
J9312_RS21265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J9312_RS21285	COG5658	integral membrane protein
J9312_RS21290	COG0640	Transcriptional regulator
J9312_RS21295	COG3829	transcription factor binding
J9312_RS21310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9312_RS21315	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J9312_RS21320	COG4853	Protein conserved in bacteria
J9312_RS21325	COG4863	YycH protein
J9312_RS21330	COG5002	protein histidine kinase activity
J9312_RS21335	COG0745	RESPONSE REGULATOR receiver
J9312_RS21365	COG0346	lactoylglutathione lyase activity
J9312_RS21370	COG0305	Participates in initiation and elongation during chromosome replication
J9312_RS21385	COG3093	addiction module antidote protein HigA
J9312_RS21390	COG2807	transmembrane transport
J9312_RS21395	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J9312_RS21400	COG0359	binds to the 23S rRNA
J9312_RS21405	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
J9312_RS21425	COG1733	regulation of RNA biosynthetic process
J9312_RS21430	COG1227	inorganic diphosphatase activity
J9312_RS21445	COG2271	Major facilitator Superfamily
J9312_RS21450	COG0789	Transcriptional regulator
J9312_RS21450	COG4978	Transcriptional regulator
J9312_RS21460	COG4319	ketosteroid isomerase
J9312_RS21465	COG1357	PFAM Pentapeptide repeats (8 copies)
J9312_RS21480	COG1846	Transcriptional regulator
J9312_RS21485	COG2153	protein acetylation
J9312_RS21490	COG2364	Membrane
J9312_RS21495	COG0456	acetyltransferase
J9312_RS21500	COG2315	Protein conserved in bacteria
J9312_RS21505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J9312_RS21515	COG2814	Major facilitator Superfamily
J9312_RS21520	COG1331	Highly conserved protein containing a thioredoxin domain
J9312_RS21525	COG1266	CAAX protease self-immunity
J9312_RS21530	COG0477	Major facilitator Superfamily
J9312_RS21530	COG2814	Major facilitator Superfamily
J9312_RS21535	COG0110	maltose O-acetyltransferase activity
J9312_RS21540	COG0346	lactoylglutathione lyase activity
J9312_RS21545	COG1609	Transcriptional regulator
J9312_RS21550	COG0708	Exodeoxyribonuclease III
J9312_RS21555	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J9312_RS21560	COG0629	single-stranded DNA binding
J9312_RS21565	COG0360	Binds together with S18 to 16S ribosomal RNA
J9312_RS21570	COG0012	GTP binding
J9312_RS21575	COG0243	molybdopterin cofactor binding
J9312_RS21580	COG4481	Protein conserved in bacteria
J9312_RS21585	COG3949	Membrane
J9312_RS21595	COG1475	DNA binding
J9312_RS21600	COG1192	Involved in chromosome partitioning
J9312_RS21610	COG1475	DNA binding
J9312_RS21615	COG0357	Ribosomal RNA small subunit methyltransferase G
J9312_RS21620	COG0445	tRNA wobble uridine modification
J9312_RS21625	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J9312_RS21630	COG1847	R3H domain protein
J9312_RS21635	COG0706	membrane insertase activity
J9312_RS21640	COG0594	ribonuclease P activity