locus-tag	class	description
AWV81_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWV81_RS00010	COG0592	DNA-directed DNA polymerase activity
AWV81_RS00015	COG2501	S4 domain
AWV81_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AWV81_RS00030	COG0187	DNA topoisomerase II activity
AWV81_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWV81_RS00070	COG0517	IMP dehydrogenase activity
AWV81_RS00070	COG0516	GMP reductase activity
AWV81_RS00075	COG1686	Belongs to the peptidase S11 family
AWV81_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AWV81_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AWV81_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AWV81_RS00100	COG1428	Deoxynucleoside kinase
AWV81_RS00105	COG1428	Deoxynucleoside kinase
AWV81_RS00110	COG1388	LysM domain
AWV81_RS00110	COG3858	chitin binding
AWV81_RS00115	COG1335	isochorismatase
AWV81_RS00120	COG0590	tRNA wobble adenosine to inosine editing
AWV81_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWV81_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AWV81_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AWV81_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AWV81_RS00190	COG3853	Toxic anion resistance protein (TelA)
AWV81_RS00195	COG1982	Orn Lys Arg decarboxylase major
AWV81_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AWV81_RS00205	COG3870	Protein conserved in bacteria
AWV81_RS00210	COG1728	Protein conserved in bacteria
AWV81_RS00215	COG0470	DNA polymerase III
AWV81_RS00220	COG1774	PSP1 C-terminal conserved region
AWV81_RS00225	COG4467	Involved in initiation control of chromosome replication
AWV81_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AWV81_RS00235	COG2827	Endonuclease containing a URI domain
AWV81_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AWV81_RS00245	COG2002	toxin-antitoxin pair type II binding
AWV81_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWV81_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWV81_RS00255	COG0084	hydrolase, TatD family'
AWV81_RS00260	COG3583	domain protein
AWV81_RS00260	COG3584	3D domain protein
AWV81_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AWV81_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AWV81_RS00280	COG4466	Protein conserved in bacteria
AWV81_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AWV81_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWV81_RS00300	COG0251	oxidation-reduction process
AWV81_RS00305	COG2088	sporulation resulting in formation of a cellular spore
AWV81_RS00315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AWV81_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWV81_RS00325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AWV81_RS00330	COG0193	aminoacyl-tRNA hydrolase activity
AWV81_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AWV81_RS00345	COG2002	toxin-antitoxin pair type II binding
AWV81_RS00350	COG2244	polysaccharide biosynthetic process
AWV81_RS00355	COG3956	TIGRFAM MazG family protein
AWV81_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AWV81_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AWV81_RS00380	COG1098	S1 RNA binding domain
AWV81_RS00395	COG2208	phosphoserine phosphatase activity
AWV81_RS00400	COG2304	oxidoreductase activity
AWV81_RS00405	COG0515	serine threonine protein kinase
AWV81_RS00410	COG0037	tRNA processing
AWV81_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AWV81_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWV81_RS00425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AWV81_RS00430	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AWV81_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWV81_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWV81_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWV81_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
AWV81_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWV81_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AWV81_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AWV81_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWV81_RS00475	COG1396	sequence-specific DNA binding
AWV81_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWV81_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AWV81_RS00565	COG4463	regulation of RNA biosynthetic process
AWV81_RS00570	COG3880	PFAM UvrB UvrC protein
AWV81_RS00575	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AWV81_RS00580	COG0542	response to heat
AWV81_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AWV81_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AWV81_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
AWV81_RS00600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AWV81_RS00605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AWV81_RS00610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWV81_RS00620	COG1045	serine acetyltransferase
AWV81_RS00625	COG0215	cysteine-tRNA ligase activity
AWV81_RS00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWV81_RS00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWV81_RS00640	COG3688	RNA-binding protein containing a PIN domain
AWV81_RS00645	COG1595	DNA-templated transcription, initiation
AWV81_RS00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWV81_RS00660	COG0250	Participates in transcription elongation, termination and antitermination
AWV81_RS00670	COG0081	regulation of translation
AWV81_RS00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AWV81_RS00685	COG2813	Specifically methylates the guanine in position
AWV81_RS00690	COG0085	RNA polymerase activity
AWV81_RS00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWV81_RS00700	COG1358	cellular component organization or biogenesis
AWV81_RS00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AWV81_RS00710	COG0049	tRNA binding
AWV81_RS00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWV81_RS00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AWV81_RS00725	COG0596	Alpha beta hydrolase
AWV81_RS00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AWV81_RS00740	COG0088	Forms part of the polypeptide exit tunnel
AWV81_RS00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWV81_RS00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AWV81_RS00770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AWV81_RS00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AWV81_RS00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AWV81_RS00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWV81_RS00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AWV81_RS00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AWV81_RS00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AWV81_RS00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AWV81_RS00830	COG0200	Binds to the 23S rRNA
AWV81_RS00835	COG0201	protein transport
AWV81_RS00840	COG0563	adenylate kinase activity
AWV81_RS00845	COG0024	Methionine aminopeptidase
AWV81_RS00850	COG2163	COG2163 Ribosomal protein L14E L6E L27E
AWV81_RS00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AWV81_RS00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AWV81_RS00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AWV81_RS00875	COG0202	RNA polymerase activity
AWV81_RS00880	COG0203	ribosomal protein L17
AWV81_RS00885	COG1122	ATPase activity
AWV81_RS00890	COG1122	ATPase activity
AWV81_RS00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AWV81_RS00900	COG0101	tRNA pseudouridine synthase activity
AWV81_RS00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AWV81_RS00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AWV81_RS00920	COG2226	methyltransferase
AWV81_RS00930	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWV81_RS00935	COG0489	protein tyrosine kinase activity
AWV81_RS00945	COG2194	sulfuric ester hydrolase activity
AWV81_RS00950	COG0726	polysaccharide deacetylase
AWV81_RS01035	COG0659	secondary active sulfate transmembrane transporter activity
AWV81_RS01040	COG0385	Bile acid
AWV81_RS01045	COG2819	hydrolase of the alpha beta superfamily
AWV81_RS01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_RS01055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_RS01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWV81_RS01065	COG2207	Transcriptional regulator
AWV81_RS01065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWV81_RS01070	COG3876	Protein conserved in bacteria
AWV81_RS01075	COG1472	Belongs to the glycosyl hydrolase 3 family
AWV81_RS01080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AWV81_RS01085	COG1263	PTS System
AWV81_RS01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_RS01090	COG1737	Transcriptional regulator
AWV81_RS01095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWV81_RS01100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_RS01105	COG1683	Conserved Protein
AWV81_RS01135	COG1595	DNA-templated transcription, initiation
AWV81_RS01140	COG5662	AntiSigma factor
AWV81_RS01145	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AWV81_RS01150	COG4856	YbbR-like protein
AWV81_RS01155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWV81_RS01160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AWV81_RS01170	COG2169	Transcriptional regulator
AWV81_RS01175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AWV81_RS01180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWV81_RS01185	COG3002	Belongs to the UPF0753 family
AWV81_RS01190	COG0288	reversible hydration of carbon dioxide
AWV81_RS01200	COG5609	conserved protein (DUF2294)
AWV81_RS01205	COG0745	RESPONSE REGULATOR receiver
AWV81_RS01210	COG0642	Histidine kinase
AWV81_RS01220	COG0515	serine threonine protein kinase
AWV81_RS01235	COG1113	amino acid transport
AWV81_RS01250	COG2602	Beta-lactamase
AWV81_RS01255	COG2124	cytochrome p450
AWV81_RS01265	COG0531	amino acid
AWV81_RS01270	COG0584	glycerophosphoryl diester phosphodiesterase
AWV81_RS01275	COG2271	Major facilitator Superfamily
AWV81_RS01285	COG0456	acetyltransferase
AWV81_RS01285	COG1846	Transcriptional regulator
AWV81_RS01305	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_RS01310	COG0697	spore germination
AWV81_RS01315	COG1917	Cupin 2, conserved barrel domain protein
AWV81_RS01315	COG2207	Transcriptional regulator
AWV81_RS01330	COG3179	chitinase
AWV81_RS01340	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AWV81_RS01345	COG3591	Belongs to the peptidase S1B family
AWV81_RS01355	COG0596	Alpha beta hydrolase
AWV81_RS01360	COG1183	phosphatidylcholine synthase activity
AWV81_RS01365	COG0586	Pfam SNARE associated Golgi protein
AWV81_RS01370	COG0688	phosphatidylethanolamine metabolic process
AWV81_RS01380	COG2312	Erythromycin esterase
AWV81_RS01385	COG2207	Transcriptional regulator
AWV81_RS01390	COG1054	Belongs to the UPF0176 family
AWV81_RS01395	COG1301	dicarboxylic acid transport
AWV81_RS01400	COG2190	(PTS) system
AWV81_RS01400	COG1263	PTS System
AWV81_RS01400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_RS01405	COG0363	glucosamine-6-phosphate deaminase activity
AWV81_RS01410	COG2188	Transcriptional regulator
AWV81_RS01420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWV81_RS01425	COG0833	amino acid
AWV81_RS01430	COG2040	homocysteine
AWV81_RS01445	COG2066	Belongs to the glutaminase family
AWV81_RS01450	COG4191	Histidine kinase
AWV81_RS01455	COG0784	Response regulator, receiver
AWV81_RS01460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWV81_RS01465	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_RS01470	COG2271	Major facilitator Superfamily
AWV81_RS01475	COG4948	Mandelate Racemase Muconate Lactonizing
AWV81_RS01480	COG2186	Transcriptional regulator
AWV81_RS01485	COG2721	sulfolactate sulfo-lyase activity
AWV81_RS01490	COG3173	Aminoglycoside phosphotransferase
AWV81_RS01500	COG0697	spore germination
AWV81_RS01505	COG0745	RESPONSE REGULATOR receiver
AWV81_RS01510	COG2205	protein histidine kinase activity
AWV81_RS01515	COG1131	(ABC) transporter
AWV81_RS01535	COG3773	Cell wall hydrolase
AWV81_RS01540	COG2304	oxidoreductase activity
AWV81_RS01550	COG3540	Alkaline phosphatase
AWV81_RS01555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWV81_RS01560	COG0805	protein transport
AWV81_RS01565	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AWV81_RS01570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWV81_RS01575	COG0477	Major facilitator Superfamily
AWV81_RS01580	COG1309	transcriptional regulator
AWV81_RS01585	COG0252	asparaginase activity
AWV81_RS01590	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AWV81_RS01595	COG1714	RDD family
AWV81_RS01600	COG3012	SEC-C Motif Domain Protein
AWV81_RS01600	COG1405	negative regulation of cell septum assembly
AWV81_RS01610	COG3279	Response regulator of the LytR AlgR family
AWV81_RS01620	COG1668	transmembrane transport
AWV81_RS01625	COG0667	Aldo Keto reductase
AWV81_RS01635	COG1595	DNA-templated transcription, initiation
AWV81_RS01640	COG1595	DNA-templated transcription, initiation
AWV81_RS01645	COG1876	peptidase activity
AWV81_RS01655	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS01660	COG0366	Alpha amylase catalytic
AWV81_RS01665	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWV81_RS01670	COG1121	(ABC) transporter
AWV81_RS01675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWV81_RS01685	COG2310	stress, protein
AWV81_RS01690	COG2310	stress, protein
AWV81_RS01695	COG2310	stress, protein
AWV81_RS01700	COG0861	Integral membrane protein TerC family
AWV81_RS01710	COG3853	Toxic anion resistance protein (TelA)
AWV81_RS01720	COG2801	Transposase and inactivated derivatives
AWV81_RS01725	COG0477	Major facilitator Superfamily
AWV81_RS01730	COG2814	Major facilitator Superfamily
AWV81_RS01735	COG0640	Transcriptional regulator
AWV81_RS01740	COG4175	Glycine betaine
AWV81_RS01740	COG0517	IMP dehydrogenase activity
AWV81_RS01745	COG4176	ABC-type proline glycine betaine transport system permease component
AWV81_RS01750	COG2113	Glycine betaine
AWV81_RS01755	COG1473	amidohydrolase
AWV81_RS01760	COG1288	antiporter activity
AWV81_RS01780	COG0039	L-malate dehydrogenase activity
AWV81_RS01790	COG3403	YqcI/YcgG family
AWV81_RS01805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AWV81_RS01810	COG1660	Displays ATPase and GTPase activities
AWV81_RS01815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AWV81_RS01830	COG2226	methyltransferase
AWV81_RS01835	COG0583	DNA-binding transcription factor activity
AWV81_RS01840	COG3458	cephalosporin-C deacetylase activity
AWV81_RS01845	COG3541	Predicted nucleotidyltransferase
AWV81_RS01850	COG0506	proline dehydrogenase activity
AWV81_RS01855	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_RS01860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWV81_RS01865	COG2508	Transcriptional regulator
AWV81_RS01870	COG3689	TIGRFAM TIGR03943 family protein
AWV81_RS01875	COG0701	Predicted permease
AWV81_RS01880	COG2267	carboxylic ester hydrolase activity
AWV81_RS01885	COG0492	ferredoxin-NADP+ reductase activity
AWV81_RS01890	COG1587	Uroporphyrinogen-III synthase
AWV81_RS01890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWV81_RS01895	COG2146	nitrite reductase [NAD(P)H] activity
AWV81_RS01900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWV81_RS01905	COG0243	molybdopterin cofactor binding
AWV81_RS01910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWV81_RS01915	COG2223	nitrite transmembrane transporter activity
AWV81_RS01920	COG1469	GTP cyclohydrolase I activity
AWV81_RS01925	COG1376	ErfK ybiS ycfS ynhG family protein
AWV81_RS01940	COG0765	amino acid transport
AWV81_RS01945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWV81_RS01955	COG1714	RDD family
AWV81_RS01965	COG1846	Transcriptional regulator
AWV81_RS01980	COG2723	6-phospho-beta-galactosidase activity
AWV81_RS01990	COG3209	COG3209 Rhs family protein
AWV81_RS02000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AWV81_RS02005	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AWV81_RS02010	COG1733	regulation of RNA biosynthetic process
AWV81_RS02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWV81_RS02025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWV81_RS02030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWV81_RS02035	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AWV81_RS02040	COG2814	Major facilitator Superfamily
AWV81_RS02050	COG0697	spore germination
AWV81_RS02055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_RS02065	COG2364	Membrane
AWV81_RS02070	COG1126	abc transporter atp-binding protein
AWV81_RS02075	COG0765	amino acid transport
AWV81_RS02080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWV81_RS02085	COG0583	DNA-binding transcription factor activity
AWV81_RS02090	COG0163	prenyltransferase activity
AWV81_RS02095	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AWV81_RS02110	COG0596	Alpha beta hydrolase
AWV81_RS02115	COG3104	oligopeptide transport
AWV81_RS02120	COG5434	Belongs to the glycosyl hydrolase 28 family
AWV81_RS02130	COG0697	spore germination
AWV81_RS02140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AWV81_RS02145	COG1136	(ABC) transporter
AWV81_RS02150	COG0577	efflux transmembrane transporter activity
AWV81_RS02155	COG0745	RESPONSE REGULATOR receiver
AWV81_RS02160	COG3850	Histidine kinase
AWV81_RS02160	COG5002	protein histidine kinase activity
AWV81_RS02165	COG0457	Tetratricopeptide repeat
AWV81_RS02180	COG0527	aspartate kinase activity
AWV81_RS02185	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_RS02190	COG4605	iron ion homeostasis
AWV81_RS02195	COG4604	ABC transporter, ATP-binding protein
AWV81_RS02200	COG4607	ABC-type enterochelin transport system periplasmic component
AWV81_RS02210	COG2814	Major facilitator Superfamily
AWV81_RS02215	COG1309	transcriptional regulator
AWV81_RS02220	COG0778	Nitroreductase
AWV81_RS02225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AWV81_RS02230	COG0640	Transcriptional regulator
AWV81_RS02235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_RS02240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AWV81_RS02245	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_RS02250	COG4975	Glucose uptake
AWV81_RS02255	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS02260	COG4549	nuclear export factor GLE1
AWV81_RS02265	COG1276	copper resistance
AWV81_RS02265	COG2372	response to copper ion
AWV81_RS02270	COG1349	DNA-binding transcription factor activity
AWV81_RS02280	COG2213	PTS system mannitol-specific
AWV81_RS02285	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_RS02290	COG0246	Mannitol dehydrogenase
AWV81_RS02295	COG0473	3-isopropylmalate dehydrogenase activity
AWV81_RS02300	COG0681	Belongs to the peptidase S26 family
AWV81_RS02310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWV81_RS02320	COG0561	phosphatase activity
AWV81_RS02325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AWV81_RS02330	COG1914	H( )-stimulated, divalent metal cation uptake system
AWV81_RS02335	COG4336	lyase activity
AWV81_RS02340	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AWV81_RS02345	COG1984	allophanate hydrolase subunit 2
AWV81_RS02350	COG1414	Transcriptional regulator
AWV81_RS02355	COG2755	lipolytic protein G-D-S-L family
AWV81_RS02365	COG2329	Antibiotic biosynthesis monooxygenase
AWV81_RS02370	COG0768	penicillin binding
AWV81_RS02375	COG4989	oxidoreductase activity
AWV81_RS02380	COG3711	transcriptional antiterminator
AWV81_RS02385	COG0318	PFAM AMP-dependent synthetase and ligase
AWV81_RS02390	COG2226	methyltransferase
AWV81_RS02395	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS02400	COG1917	Cupin 2, conserved barrel domain protein
AWV81_RS02405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_RS02410	COG3871	stress protein (general stress protein 26)
AWV81_RS02420	COG2814	Major facilitator Superfamily
AWV81_RS02425	COG1522	sequence-specific DNA binding
AWV81_RS02430	COG0551	DNA topoisomerase type I activity
AWV81_RS02430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWV81_RS02435	COG0494	nUDIX hydrolase
AWV81_RS02440	COG0028	Belongs to the TPP enzyme family
AWV81_RS02470	COG1914	H( )-stimulated, divalent metal cation uptake system
AWV81_RS02475	COG2261	transglycosylase associated protein
AWV81_RS02480	COG4876	unkown
AWV81_RS02485	COG2217	Heavy metal translocating P-type atpase
AWV81_RS02490	COG3729	General stress protein
AWV81_RS02495	COG0662	Cupin 2, conserved barrel domain protein
AWV81_RS02500	COG2329	Antibiotic biosynthesis monooxygenase
AWV81_RS02505	COG3546	catalase activity
AWV81_RS02510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AWV81_RS02515	COG3290	protein histidine kinase activity
AWV81_RS02520	COG4565	transcriptional regulatory protein
AWV81_RS02525	COG1301	dicarboxylic acid transport
AWV81_RS02530	COG0628	permease
AWV81_RS02540	COG1131	(ABC) transporter
AWV81_RS02545	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AWV81_RS02555	COG1960	acyl-CoA dehydrogenase activity
AWV81_RS02570	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWV81_RS02575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_RS02580	COG1181	Belongs to the D-alanine--D-alanine ligase family
AWV81_RS02585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWV81_RS02590	COG0513	Belongs to the DEAD box helicase family
AWV81_RS02595	COG3402	PFAM membrane-flanked domain
AWV81_RS02600	COG3428	Bacterial PH domain
AWV81_RS02605	COG0705	Rhomboid family
AWV81_RS02610	COG0736	holo-[acyl-carrier-protein] synthase activity
AWV81_RS02615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AWV81_RS02620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AWV81_RS02625	COG0864	Transcriptional regulator
AWV81_RS02630	COG2337	Toxic component of a toxin-antitoxin (TA) module
AWV81_RS02635	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_RS02640	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_RS02645	COG2172	sigma factor antagonist activity
AWV81_RS02650	COG2208	phosphoserine phosphatase activity
AWV81_RS02655	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_RS02660	COG2172	sigma factor antagonist activity
AWV81_RS02665	COG1191	sigma factor activity
AWV81_RS02670	COG2208	phosphoserine phosphatase activity
AWV81_RS02685	COG1673	EVE domain
AWV81_RS02690	COG1846	Transcriptional regulator
AWV81_RS02695	COG2183	response to ionizing radiation
AWV81_RS02705	COG3091	SprT-like family
AWV81_RS02745	COG0582	viral genome integration into host DNA
AWV81_RS02750	COG2856	Zn peptidase
AWV81_RS02755	COG1396	sequence-specific DNA binding
AWV81_RS02780	COG1674	ftsk spoiiie
AWV81_RS02785	COG2946	Replication initiation factor
AWV81_RS02825	COG0433	COG0433 Predicted ATPase
AWV81_RS02835	COG5644	endopeptidase inhibitor activity
AWV81_RS02845	COG0741	lytic transglycosylase activity
AWV81_RS02845	COG0791	NLP P60 protein
AWV81_RS02860	COG0457	Tetratricopeptide repeat
AWV81_RS02890	COG0583	DNA-binding transcription factor activity
AWV81_RS02895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_RS02905	COG5444	nuclease activity
AWV81_RS02910	COG1476	TRANSCRIPTIONal
AWV81_RS02935	COG0693	protein deglycase activity
AWV81_RS02940	COG1278	Cold shock
AWV81_RS02945	COG1329	Transcriptional regulator
AWV81_RS02950	COG0697	spore germination
AWV81_RS02955	COG2207	Transcriptional regulator
AWV81_RS02955	COG1917	Cupin 2, conserved barrel domain protein
AWV81_RS02965	COG3708	Transcriptional regulator
AWV81_RS02965	COG2207	Transcriptional regulator
AWV81_RS02970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_RS02985	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AWV81_RS03000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_RS03005	COG1309	transcriptional regulator
AWV81_RS03010	COG0697	spore germination
AWV81_RS03015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_RS03020	COG2030	dehydratase
AWV81_RS03025	COG3545	Serine hydrolase
AWV81_RS03035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWV81_RS03040	COG0640	Transcriptional regulator
AWV81_RS03045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AWV81_RS03055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_RS03060	COG0697	spore germination
AWV81_RS03065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_RS03070	COG0076	glutamate decarboxylase activity
AWV81_RS03075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWV81_RS03080	COG0640	Transcriptional regulator
AWV81_RS03085	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AWV81_RS03095	COG4585	Histidine kinase
AWV81_RS03100	COG2197	response regulator
AWV81_RS03105	COG2409	Drug exporters of the RND superfamily
AWV81_RS03110	COG0596	Alpha beta hydrolase
AWV81_RS03115	COG1811	Na channel or pump
AWV81_RS03120	COG0789	Transcriptional regulator
AWV81_RS03120	COG4978	Transcriptional regulator
AWV81_RS03125	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWV81_RS03130	COG0778	Nitroreductase
AWV81_RS03135	COG0346	lactoylglutathione lyase activity
AWV81_RS03140	COG2259	Doxx family
AWV81_RS03145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_RS03175	COG2323	membrane
AWV81_RS03180	COG0071	Belongs to the small heat shock protein (HSP20) family
AWV81_RS03195	COG1309	transcriptional regulator
AWV81_RS03205	COG0456	acetyltransferase
AWV81_RS03210	COG0488	(ABC) transporter
AWV81_RS03215	COG1113	amino acid transport
AWV81_RS03220	COG2318	DinB family
AWV81_RS03225	COG1846	Transcriptional regulator
AWV81_RS03230	COG2409	Drug exporters of the RND superfamily
AWV81_RS03230	COG1033	growth of symbiont in host cell
AWV81_RS03235	COG0778	Nitroreductase
AWV81_RS03240	COG1846	Transcriptional regulator
AWV81_RS03245	COG2814	Major facilitator Superfamily
AWV81_RS03250	COG0730	response to heat
AWV81_RS03255	COG1802	Transcriptional regulator
AWV81_RS03260	COG1388	LysM domain
AWV81_RS03260	COG3858	chitin binding
AWV81_RS03265	COG1819	glycosyl
AWV81_RS03275	COG1785	Belongs to the alkaline phosphatase family
AWV81_RS03280	COG5646	InterPro IPR014922
AWV81_RS03290	COG0454	-acetyltransferase
AWV81_RS03295	COG1078	dGTPase activity
AWV81_RS03300	COG1388	LysM domain
AWV81_RS03305	COG2814	Major facilitator Superfamily
AWV81_RS03310	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWV81_RS03325	COG2723	6-phospho-beta-galactosidase activity
AWV81_RS03330	COG2188	Transcriptional regulator
AWV81_RS03335	COG1940	carbohydrate kinase activity
AWV81_RS03345	COG4124	Belongs to the glycosyl hydrolase 26 family
AWV81_RS03390	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AWV81_RS03395	COG0802	atpase or kinase
AWV81_RS03400	COG1214	PFAM Peptidase M22, glycoprotease
AWV81_RS03405	COG0456	acetyltransferase
AWV81_RS03410	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AWV81_RS03415	COG0488	(ABC) transporter
AWV81_RS03420	COG0315	cyclic pyranopterin monophosphate synthase activity
AWV81_RS03425	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AWV81_RS03430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWV81_RS03435	COG0805	protein transport
AWV81_RS03445	COG1266	CAAX protease self-immunity
AWV81_RS03455	COG0459	protein refolding
AWV81_RS03470	COG0457	Tetratricopeptide repeat
AWV81_RS03475	COG1063	alcohol dehydrogenase
AWV81_RS03480	COG2211	Major facilitator Superfamily
AWV81_RS03485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWV81_RS03495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWV81_RS03500	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AWV81_RS03505	COG4260	virion core protein, lumpy skin disease virus
AWV81_RS03515	COG2814	Major facilitator Superfamily
AWV81_RS03520	COG1063	alcohol dehydrogenase
AWV81_RS03525	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWV81_RS03530	COG0823	Involved in the tonB-independent uptake of proteins
AWV81_RS03535	COG2801	Transposase and inactivated derivatives
AWV81_RS03555	COG2267	carboxylic ester hydrolase activity
AWV81_RS03565	COG2132	Multicopper oxidase
AWV81_RS03570	COG1113	amino acid transport
AWV81_RS03580	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWV81_RS03585	COG0714	Associated with various cellular activities
AWV81_RS03590	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AWV81_RS03595	COG1305	Transglutaminase-like
AWV81_RS03600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AWV81_RS03600	COG0519	Catalyzes the synthesis of GMP from XMP
AWV81_RS03610	COG2252	PERMEase
AWV81_RS03615	COG3064	Membrane
AWV81_RS03625	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AWV81_RS03635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AWV81_RS03640	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AWV81_RS03645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AWV81_RS03650	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AWV81_RS03655	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWV81_RS03660	COG0047	phosphoribosylformylglycinamidine synthase activity
AWV81_RS03665	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWV81_RS03670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AWV81_RS03675	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AWV81_RS03680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AWV81_RS03685	COG0138	bifunctional purine biosynthesis protein purh
AWV81_RS03690	COG0151	Belongs to the GarS family
AWV81_RS03695	COG1522	sequence-specific DNA binding
AWV81_RS03700	COG0531	amino acid
AWV81_RS03710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AWV81_RS03715	COG1470	cell adhesion involved in biofilm formation
AWV81_RS03720	COG4496	protein, YerC YecD
AWV81_RS03725	COG0069	glutamate synthase activity
AWV81_RS03735	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AWV81_RS03740	COG0210	DNA helicase
AWV81_RS03745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWV81_RS03750	COG4851	CamS sex pheromone cAM373 precursor
AWV81_RS03760	COG2801	Transposase and inactivated derivatives
AWV81_RS03765	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWV81_RS03770	COG1285	pathogenesis
AWV81_RS03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWV81_RS03780	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWV81_RS03785	COG0154	amidase activity
AWV81_RS03790	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWV81_RS03795	COG1309	transcriptional regulator
AWV81_RS03800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AWV81_RS03805	COG1597	lipid kinase activity
AWV81_RS03810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWV81_RS03835	COG5444	nuclease activity
AWV81_RS03845	COG0457	Tetratricopeptide repeat
AWV81_RS03855	COG0217	transcriptional regulatory protein
AWV81_RS03865	COG1309	transcriptional regulator
AWV81_RS03880	COG3546	catalase activity
AWV81_RS03885	COG0454	-acetyltransferase
AWV81_RS03895	COG5578	integral membrane protein
AWV81_RS03900	COG2972	Histidine kinase
AWV81_RS03910	COG1653	transport
AWV81_RS03915	COG1175	transmembrane transport
AWV81_RS03920	COG0395	ABC-type sugar transport system, permease component
AWV81_RS03925	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AWV81_RS03930	COG2207	Transcriptional regulator
AWV81_RS03935	COG2755	lipolytic protein G-D-S-L family
AWV81_RS03945	COG5578	integral membrane protein
AWV81_RS03950	COG3401	FG-GAP repeat protein
AWV81_RS03955	COG3401	FG-GAP repeat protein
AWV81_RS03960	COG2755	lipolytic protein G-D-S-L family
AWV81_RS03975	COG1653	transport
AWV81_RS03980	COG4209	transmembrane transport
AWV81_RS03985	COG0395	ABC-type sugar transport system, permease component
AWV81_RS03990	COG1486	melibiose metabolic process
AWV81_RS03995	COG2323	membrane
AWV81_RS04000	COG2329	Antibiotic biosynthesis monooxygenase
AWV81_RS04005	COG0346	lactoylglutathione lyase activity
AWV81_RS04020	COG5583	Uncharacterized small protein (DUF2292)
AWV81_RS04025	COG0670	Belongs to the BI1 family
AWV81_RS04030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWV81_RS04040	COG3328	transposase activity
AWV81_RS04050	COG2124	cytochrome p450
AWV81_RS04050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWV81_RS04055	COG1368	sulfuric ester hydrolase activity
AWV81_RS04060	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AWV81_RS04065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWV81_RS04070	COG1442	glycosyl transferase family 8
AWV81_RS04075	COG1216	Glycosyl transferase, family 2
AWV81_RS04080	COG1442	glycosyl transferase family 8
AWV81_RS04085	COG2223	nitrite transmembrane transporter activity
AWV81_RS04090	COG1011	Hydrolase
AWV81_RS04095	COG0531	amino acid
AWV81_RS04100	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_RS04105	COG0840	transmembrane signaling receptor activity
AWV81_RS04110	COG0488	(ABC) transporter
AWV81_RS04120	COG0789	Transcriptional regulator
AWV81_RS04125	COG2814	Major facilitator Superfamily
AWV81_RS04140	COG2801	Transposase and inactivated derivatives
AWV81_RS04145	COG0488	(ABC) transporter
AWV81_RS04150	COG0513	Belongs to the DEAD box helicase family
AWV81_RS04160	COG3866	Pectate lyase
AWV81_RS04165	COG0471	metal ion transport
AWV81_RS04170	COG3290	protein histidine kinase activity
AWV81_RS04175	COG4565	transcriptional regulatory protein
AWV81_RS04180	COG3181	Tripartite tricarboxylate transporter family receptor
AWV81_RS04190	COG2851	Citrate transporter
AWV81_RS04195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWV81_RS04200	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AWV81_RS04205	COG1254	Belongs to the acylphosphatase family
AWV81_RS04210	COG2258	MOSC domain
AWV81_RS04230	COG0024	Methionine aminopeptidase
AWV81_RS04235	COG1263	PTS System
AWV81_RS04235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_RS04240	COG1368	sulfuric ester hydrolase activity
AWV81_RS04250	COG1115	amino acid carrier protein
AWV81_RS04255	COG0531	amino acid
AWV81_RS04260	COG0697	spore germination
AWV81_RS04265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_RS04265	COG1263	PTS System
AWV81_RS04270	COG0366	Alpha amylase catalytic
AWV81_RS04275	COG2188	Transcriptional regulator
AWV81_RS04280	COG0778	Nitroreductase
AWV81_RS04285	COG0737	Belongs to the 5'-nucleotidase family
AWV81_RS04290	COG0693	protein deglycase activity
AWV81_RS04300	COG2801	Transposase and inactivated derivatives
AWV81_RS04305	COG2814	Major facilitator Superfamily
AWV81_RS04310	COG4840	Belongs to the UPF0435 family
AWV81_RS04315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWV81_RS04320	COG4980	gas vesicle protein
AWV81_RS04325	COG1295	ribonuclease BN
AWV81_RS04335	COG0477	Major facilitator Superfamily
AWV81_RS04345	COG0387	Pfam Sodium calcium exchanger
AWV81_RS04355	COG0668	transmembrane transport
AWV81_RS04360	COG0535	radical SAM domain protein
AWV81_RS04370	COG0726	polysaccharide deacetylase
AWV81_RS04375	COG2084	Dehydrogenase
AWV81_RS04380	COG0598	Magnesium transport protein CorA
AWV81_RS04385	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AWV81_RS04390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWV81_RS04400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWV81_RS04405	COG4637	Psort location Cytoplasmic, score
AWV81_RS04415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWV81_RS04420	COG0022	dehydrogenase e1 component
AWV81_RS04425	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWV81_RS04430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWV81_RS04435	COG3284	Transcriptional regulator
AWV81_RS04445	COG1742	UPF0060 membrane protein
AWV81_RS04470	COG4842	Belongs to the WXG100 family
AWV81_RS04475	COG1486	melibiose metabolic process
AWV81_RS04480	COG1737	Transcriptional regulator
AWV81_RS04485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_RS04485	COG1263	PTS System
AWV81_RS04490	COG5434	Belongs to the glycosyl hydrolase 28 family
AWV81_RS04495	COG1132	(ABC) transporter
AWV81_RS04500	COG1132	(ABC) transporter
AWV81_RS04505	COG2259	Doxx family
AWV81_RS04510	COG2514	catechol 2,3-dioxygenase activity
AWV81_RS04515	COG1917	Cupin 2, conserved barrel domain protein
AWV81_RS04515	COG4977	sequence-specific DNA binding
AWV81_RS04520	COG2814	Major facilitator Superfamily
AWV81_RS04525	COG1082	Xylose isomerase domain protein TIM barrel
AWV81_RS04535	COG4585	Histidine kinase
AWV81_RS04540	COG2197	response regulator
AWV81_RS04545	COG1131	(ABC) transporter
AWV81_RS04550	COG0842	Transport permease protein
AWV81_RS04550	COG1511	domain protein
AWV81_RS04555	COG0842	Transport permease protein
AWV81_RS04560	COG1695	Transcriptional regulator
AWV81_RS04565	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AWV81_RS04570	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AWV81_RS04575	COG1309	transcriptional regulator
AWV81_RS04580	COG2814	Major facilitator Superfamily
AWV81_RS04585	COG2318	DinB family
AWV81_RS04595	COG1846	Transcriptional regulator
AWV81_RS04600	COG0392	lysyltransferase activity
AWV81_RS04600	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AWV81_RS04605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWV81_RS04610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_RS04615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_RS04620	COG0384	phenazine biosynthesis protein PhzF
AWV81_RS04625	COG0778	Nitroreductase
AWV81_RS04640	COG1090	epimerase
AWV81_RS04645	COG2137	regulation of response to DNA damage stimulus
AWV81_RS04660	COG2814	Major facilitator Superfamily
AWV81_RS04675	COG3103	Sh3 type 3 domain protein
AWV81_RS04680	COG5658	integral membrane protein
AWV81_RS04685	COG0596	Alpha beta hydrolase
AWV81_RS04690	COG0463	Glycosyl transferase, family 2
AWV81_RS04695	COG4485	Bacterial membrane protein, YfhO
AWV81_RS04700	COG1988	membrane-bound metal-dependent
AWV81_RS04705	COG1194	a g-specific adenine glycosylase
AWV81_RS04715	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS04730	COG3557	Belongs to the UPF0374 family
AWV81_RS04735	COG1132	(ABC) transporter
AWV81_RS04740	COG4129	membrane
AWV81_RS04745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWV81_RS04750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AWV81_RS04755	COG0735	belongs to the Fur family
AWV81_RS04870	COG4326	sporulation control protein
AWV81_RS04880	COG5577	PFAM Coat F domain
AWV81_RS04885	COG3340	Belongs to the peptidase S51 family
AWV81_RS04890	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AWV81_RS04905	COG0753	catalase activity
AWV81_RS04910	COG1116	anion transmembrane transporter activity
AWV81_RS04915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWV81_RS04920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWV81_RS04925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWV81_RS04935	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AWV81_RS04945	COG1476	TRANSCRIPTIONal
AWV81_RS04955	COG3382	B3 4 domain protein
AWV81_RS04960	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AWV81_RS04970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AWV81_RS04975	COG0789	Transcriptional regulator
AWV81_RS04980	COG1664	Polymer-forming cytoskeletal
AWV81_RS04985	COG1664	Polymer-forming cytoskeletal
AWV81_RS04990	COG2766	serine protein kinase
AWV81_RS04995	COG2718	Belongs to the UPF0229 family
AWV81_RS05005	COG1846	Transcriptional regulator
AWV81_RS05010	COG1566	PFAM secretion protein HlyD family protein
AWV81_RS05015	COG2814	Major facilitator Superfamily
AWV81_RS05020	COG0655	NAD(P)H dehydrogenase (quinone) activity
AWV81_RS05035	COG1725	Transcriptional regulator
AWV81_RS05040	COG1131	(ABC) transporter
AWV81_RS05045	COG1131	(ABC) transporter
AWV81_RS05050	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AWV81_RS05055	COG1278	Cold shock
AWV81_RS05060	COG1464	Belongs to the NlpA lipoprotein family
AWV81_RS05065	COG3706	GGDEF domain
AWV81_RS05070	COG1823	symporter activity
AWV81_RS05075	COG5444	nuclease activity
AWV81_RS05100	COG0582	viral genome integration into host DNA
AWV81_RS05150	COG5644	endopeptidase inhibitor activity
AWV81_RS05155	COG0741	lytic transglycosylase activity
AWV81_RS05155	COG0791	NLP P60 protein
AWV81_RS05175	COG0457	Tetratricopeptide repeat
AWV81_RS05195	COG5577	PFAM Coat F domain
AWV81_RS05200	COG4085	toxin activity
AWV81_RS05200	COG1525	nuclease
AWV81_RS05200	COG0737	Belongs to the 5'-nucleotidase family
AWV81_RS05205	COG3764	Sortase (surface protein transpeptidase)
AWV81_RS05210	COG0564	pseudouridine synthase activity
AWV81_RS05220	COG0517	IMP dehydrogenase activity
AWV81_RS05225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWV81_RS05230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWV81_RS05230	COG3153	acetyltransferase
AWV81_RS05235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AWV81_RS05240	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AWV81_RS05245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWV81_RS05250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AWV81_RS05255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AWV81_RS05260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWV81_RS05265	COG2203	Gaf domain
AWV81_RS05265	COG4585	Histidine kinase
AWV81_RS05270	COG2197	response regulator
AWV81_RS05275	COG0431	NADPH-dependent FMN reductase
AWV81_RS05290	COG1388	LysM domain
AWV81_RS05290	COG0791	NLP P60 protein
AWV81_RS05295	COG1959	2 iron, 2 sulfur cluster binding
AWV81_RS05300	COG0668	transmembrane transport
AWV81_RS05305	COG2719	SpoVR family
AWV81_RS05310	COG1785	Belongs to the alkaline phosphatase family
AWV81_RS05315	COG1388	LysM domain
AWV81_RS05315	COG0791	NLP P60 protein
AWV81_RS05320	COG0583	DNA-binding transcription factor activity
AWV81_RS05325	COG0372	Belongs to the citrate synthase family
AWV81_RS05330	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS05335	COG0531	amino acid
AWV81_RS05340	COG0733	neurotransmitter:sodium symporter activity
AWV81_RS05345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_RS05350	COG0456	acetyltransferase
AWV81_RS05365	COG1595	DNA-templated transcription, initiation
AWV81_RS05370	COG0667	Aldo Keto reductase
AWV81_RS05375	COG0204	Acyl-transferase
AWV81_RS05380	COG1253	flavin adenine dinucleotide binding
AWV81_RS05385	COG0789	Transcriptional regulator
AWV81_RS05395	COG1253	flavin adenine dinucleotide binding
AWV81_RS05400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AWV81_RS05405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AWV81_RS05410	COG0584	glycerophosphoryl diester phosphodiesterase
AWV81_RS05420	COG0668	transmembrane transport
AWV81_RS05425	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AWV81_RS05430	COG0726	polysaccharide deacetylase
AWV81_RS05435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWV81_RS05440	COG1757	Na H antiporter
AWV81_RS05445	COG0589	response to stress
AWV81_RS05455	COG1132	(ABC) transporter
AWV81_RS05460	COG1132	(ABC) transporter
AWV81_RS05465	COG0702	epimerase
AWV81_RS05485	COG0189	ligase activity
AWV81_RS05490	COG0189	ligase activity
AWV81_RS05495	COG4399	Belongs to the UPF0754 family
AWV81_RS05500	COG3679	Belongs to the UPF0342 family
AWV81_RS05510	COG0561	phosphatase activity
AWV81_RS05515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWV81_RS05520	COG0475	glutathione-regulated potassium exporter activity
AWV81_RS05525	COG0490	domain, Protein
AWV81_RS05535	COG1024	Enoyl-CoA hydratase
AWV81_RS05545	COG4152	abc transporter atp-binding protein
AWV81_RS05550	COG1668	transmembrane transport
AWV81_RS05555	COG0420	3'-5' exonuclease activity
AWV81_RS05560	COG4717	serine-type aminopeptidase activity
AWV81_RS05565	COG3481	metal-dependent phosphohydrolase, HD sub domain
AWV81_RS05575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWV81_RS05595	COG1846	Transcriptional regulator
AWV81_RS05600	COG4980	gas vesicle protein
AWV81_RS05615	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AWV81_RS05620	COG0537	adenosine 5'-monophosphoramidase activity
AWV81_RS05625	COG1131	(ABC) transporter
AWV81_RS05630	COG4473	ABC transporter
AWV81_RS05640	COG1473	amidohydrolase
AWV81_RS05645	COG3069	C4-dicarboxylate transmembrane transporter activity
AWV81_RS05655	COG2329	Antibiotic biosynthesis monooxygenase
AWV81_RS05660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWV81_RS05665	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AWV81_RS05670	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWV81_RS05675	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AWV81_RS05680	COG1309	transcriptional regulator
AWV81_RS05685	COG1511	domain protein
AWV81_RS05690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWV81_RS05695	COG4377	Putative membrane peptidase family (DUF2324)
AWV81_RS05705	COG1363	Peptidase, m42
AWV81_RS05710	COG4405	Protein conserved in bacteria
AWV81_RS05715	COG1301	dicarboxylic acid transport
AWV81_RS05725	COG1234	tRNA 3'-trailer cleavage
AWV81_RS05730	COG0095	Lipoate-protein ligase
AWV81_RS05735	COG0702	epimerase
AWV81_RS05740	COG0318	PFAM AMP-dependent synthetase and ligase
AWV81_RS05750	COG0501	Belongs to the peptidase M48B family
AWV81_RS05760	COG0456	acetyltransferase
AWV81_RS05765	COG0604	alcohol dehydrogenase
AWV81_RS05770	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AWV81_RS05775	COG0406	alpha-ribazole phosphatase activity
AWV81_RS05780	COG0183	Belongs to the thiolase family
AWV81_RS05785	COG0318	PFAM AMP-dependent synthetase and ligase
AWV81_RS05790	COG1268	BioY protein
AWV81_RS05795	COG0840	transmembrane signaling receptor activity
AWV81_RS05805	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS05815	COG4903	ComK protein
AWV81_RS05820	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS05830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWV81_RS05845	COG0398	Pfam SNARE associated Golgi protein
AWV81_RS05850	COG0681	Belongs to the peptidase S26 family
AWV81_RS05855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWV81_RS05860	COG1846	Transcriptional regulator
AWV81_RS05880	COG0738	Major facilitator superfamily
AWV81_RS05885	COG0673	inositol 2-dehydrogenase activity
AWV81_RS05890	COG0561	phosphatase activity
AWV81_RS05895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AWV81_RS05900	COG1609	Transcriptional regulator
AWV81_RS05905	COG3180	Ammonia monooxygenase
AWV81_RS05910	COG2814	Major facilitator Superfamily
AWV81_RS05910	COG0477	Major facilitator Superfamily
AWV81_RS05915	COG4533	DNA binding
AWV81_RS05930	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AWV81_RS05935	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AWV81_RS05940	COG1074	ATP-dependent DNA helicase activity
AWV81_RS05945	COG0420	3'-5' exonuclease activity
AWV81_RS05950	COG0419	ATPase involved in DNA repair
AWV81_RS05955	COG1403	HNH endonuclease
AWV81_RS06000	COG5337	Spore coat protein CotH
AWV81_RS06005	COG0179	Fumarylacetoacetate (FAA) hydrolase
AWV81_RS06015	COG1404	Belongs to the peptidase S8 family
AWV81_RS06025	COG0367	asparagine synthase
AWV81_RS06030	COG1562	ergosterol biosynthetic process
AWV81_RS06035	COG0534	Mate efflux family protein
AWV81_RS06040	COG2207	Transcriptional regulator
AWV81_RS06040	COG1917	Cupin 2, conserved barrel domain protein
AWV81_RS06045	COG1609	Transcriptional regulator
AWV81_RS06050	COG0673	inositol 2-dehydrogenase activity
AWV81_RS06055	COG2318	DinB family
AWV81_RS06060	COG1279	arginine transmembrane transporter activity
AWV81_RS06065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_RS06070	COG1357	PFAM Pentapeptide repeats (8 copies)
AWV81_RS06075	COG2267	carboxylic ester hydrolase activity
AWV81_RS06080	COG0454	-acetyltransferase
AWV81_RS06085	COG2153	protein acetylation
AWV81_RS06090	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AWV81_RS06090	COG0646	methionine synthase
AWV81_RS06095	COG1666	GTP binding
AWV81_RS06100	COG2996	Protein conserved in bacteria
AWV81_RS06110	COG1307	EDD domain protein, DegV family
AWV81_RS06115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWV81_RS06135	COG0561	phosphatase activity
AWV81_RS06140	COG1073	alpha beta
AWV81_RS06145	COG2151	metal-sulfur cluster biosynthetic enzyme
AWV81_RS06165	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AWV81_RS06170	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AWV81_RS06180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWV81_RS06185	COG0505	Belongs to the CarA family
AWV81_RS06190	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWV81_RS06195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AWV81_RS06200	COG2801	Transposase and inactivated derivatives
AWV81_RS06220	COG2267	carboxylic ester hydrolase activity
AWV81_RS06230	COG1744	ABC transporter substrate-binding protein PnrA-like
AWV81_RS06245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWV81_RS06250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWV81_RS06255	COG5504	Zn-dependent protease
AWV81_RS06260	COG0444	Belongs to the ABC transporter superfamily
AWV81_RS06265	COG4608	Belongs to the ABC transporter superfamily
AWV81_RS06275	COG0601	transmembrane transport
AWV81_RS06280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWV81_RS06290	COG0180	Tryptophanyl-tRNA synthetase
AWV81_RS06295	COG4166	transmembrane transport
AWV81_RS06300	COG0601	transmembrane transport
AWV81_RS06305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWV81_RS06310	COG0444	Belongs to the ABC transporter superfamily
AWV81_RS06315	COG4608	Belongs to the ABC transporter superfamily
AWV81_RS06320	COG2814	Major facilitator Superfamily
AWV81_RS06325	COG0456	acetyltransferase
AWV81_RS06330	COG1393	Belongs to the ArsC family
AWV81_RS06335	COG0861	Integral membrane protein TerC family
AWV81_RS06340	COG4862	establishment of competence for transformation
AWV81_RS06345	COG4469	Competence protein
AWV81_RS06350	COG1164	Oligoendopeptidase f
AWV81_RS06365	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AWV81_RS06370	COG2346	COG2346, Truncated hemoglobins
AWV81_RS06375	COG0741	lytic transglycosylase activity
AWV81_RS06380	COG4116	CYTH
AWV81_RS06390	COG2357	RelA SpoT domain protein
AWV81_RS06395	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWV81_RS06400	COG0564	pseudouridine synthase activity
AWV81_RS06405	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AWV81_RS06410	COG0475	glutathione-regulated potassium exporter activity
AWV81_RS06410	COG0569	domain protein
AWV81_RS06415	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AWV81_RS06420	COG0352	thiamine-phosphate diphosphorylase activity
AWV81_RS06425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWV81_RS06430	COG2104	thiamine diphosphate biosynthetic process
AWV81_RS06435	COG2022	thiamine diphosphate biosynthetic process
AWV81_RS06440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWV81_RS06445	COG0351	phosphomethylpyrimidine kinase
AWV81_RS06450	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AWV81_RS06510	COG0210	DNA helicase
AWV81_RS06520	COG2153	protein acetylation
AWV81_RS06525	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AWV81_RS06530	COG2382	esterase
AWV81_RS06535	COG0626	cystathionine gamma-synthase activity
AWV81_RS06540	COG0626	cystathionine gamma-synthase activity
AWV81_RS06545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_RS06550	COG5505	Protein of unknown function (DUF819)
AWV81_RS06580	COG1396	sequence-specific DNA binding
AWV81_RS06605	COG2801	Transposase and inactivated derivatives
AWV81_RS06650	COG0457	Tetratricopeptide repeat
AWV81_RS06655	COG5444	nuclease activity
AWV81_RS06665	COG3328	transposase activity
AWV81_RS06720	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AWV81_RS06730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_RS06730	COG3711	transcriptional antiterminator
AWV81_RS06735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_RS06735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWV81_RS06735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWV81_RS06740	COG1482	cell wall glycoprotein biosynthetic process
AWV81_RS06755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_RS06765	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AWV81_RS06780	COG0109	protoheme IX farnesyltransferase activity
AWV81_RS06790	COG0726	polysaccharide deacetylase
AWV81_RS06810	COG5504	Zn-dependent protease
AWV81_RS06815	COG2205	protein histidine kinase activity
AWV81_RS06830	COG2427	Protein of unknown function (DUF1641)
AWV81_RS06840	COG1051	belongs to the nudix hydrolase family
AWV81_RS06850	COG2124	cytochrome p450
AWV81_RS06855	COG1819	glycosyl
AWV81_RS06865	COG1587	Uroporphyrinogen-III synthase
AWV81_RS06870	COG0390	transport system, permease component
AWV81_RS06875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWV81_RS06880	COG0697	spore germination
AWV81_RS06895	COG1252	NADH dehydrogenase
AWV81_RS06900	COG1904	glucuronate isomerase
AWV81_RS06905	COG2211	Major facilitator Superfamily
AWV81_RS06910	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AWV81_RS06915	COG1063	alcohol dehydrogenase
AWV81_RS06920	COG1312	Catalyzes the dehydration of D-mannonate
AWV81_RS06925	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS06930	COG2271	Major facilitator Superfamily
AWV81_RS06935	COG1609	Transcriptional regulator
AWV81_RS06940	COG0246	Mannitol dehydrogenase
AWV81_RS06945	COG2721	sulfolactate sulfo-lyase activity
AWV81_RS06950	COG0730	response to heat
AWV81_RS06955	COG2318	DinB family
AWV81_RS06960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWV81_RS06965	COG2801	Transposase and inactivated derivatives
AWV81_RS06975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWV81_RS06980	COG0457	Tetratricopeptide repeat
AWV81_RS06995	COG1388	LysM domain
AWV81_RS06995	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_RS06995	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWV81_RS07005	COG4195	phage-related replication protein
AWV81_RS07010	COG3546	catalase activity
AWV81_RS07015	COG2856	Zn peptidase
AWV81_RS07020	COG1396	sequence-specific DNA binding
AWV81_RS07030	COG1522	sequence-specific DNA binding
AWV81_RS07035	COG1484	DNA-dependent DNA replication
AWV81_RS07060	COG1595	DNA-templated transcription, initiation
AWV81_RS07065	COG5484	DNA packaging
AWV81_RS07065	COG3728	DNA packaging
AWV81_RS07070	COG1783	phage Terminase large subunit
AWV81_RS07075	COG5518	Phage portal protein
AWV81_RS07080	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AWV81_RS07085	COG4653	Phage capsid family
AWV81_RS07140	COG1652	LysM domain
AWV81_RS07145	COG4193	domain, Protein
AWV81_RS07155	COG3628	GPW Gp25 family protein
AWV81_RS07160	COG3299	homolog of phage Mu protein gp47
AWV81_RS07165	COG3778	Protein conserved in bacteria
AWV81_RS07205	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_RS07205	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWV81_RS07220	COG0306	phosphate transporter
AWV81_RS07225	COG1392	Phosphate transport regulator
AWV81_RS07230	COG0531	amino acid
AWV81_RS07235	COG0346	lactoylglutathione lyase activity
AWV81_RS07240	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWV81_RS07245	COG0463	Glycosyl transferase, family 2
AWV81_RS07255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWV81_RS07260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWV81_RS07265	COG2362	D-Aminopeptidase
AWV81_RS07270	COG0601	transmembrane transport
AWV81_RS07275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWV81_RS07280	COG0444	Belongs to the ABC transporter superfamily
AWV81_RS07285	COG4166	transmembrane transport
AWV81_RS07290	COG1619	proteins homologs of microcin C7 resistance protein MccF
AWV81_RS07295	COG4948	Mandelate Racemase Muconate Lactonizing
AWV81_RS07300	COG0791	NLP P60 protein
AWV81_RS07305	COG4608	Belongs to the ABC transporter superfamily
AWV81_RS07310	COG2706	6-phosphogluconolactonase activity
AWV81_RS07320	COG1607	acyl-coa hydrolase
AWV81_RS07325	COG1017	nitric oxide dioxygenase activity
AWV81_RS07325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWV81_RS07335	COG2323	membrane
AWV81_RS07340	COG2318	DinB family
AWV81_RS07345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_RS07350	COG2076	Multidrug Resistance protein
AWV81_RS07355	COG2076	Multidrug Resistance protein
AWV81_RS07360	COG0788	formyltetrahydrofolate deformylase activity
AWV81_RS07365	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AWV81_RS07370	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWV81_RS07375	COG1764	response to oxidative stress
AWV81_RS07380	COG1846	Transcriptional regulator
AWV81_RS07385	COG1764	response to oxidative stress
AWV81_RS07395	COG0590	tRNA wobble adenosine to inosine editing
AWV81_RS07400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWV81_RS07405	COG1404	Belongs to the peptidase S8 family
AWV81_RS07410	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_RS07415	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AWV81_RS07420	COG1122	ATPase activity
AWV81_RS07425	COG4721	ABC-type cobalt transport system, permease component
AWV81_RS07435	COG0745	RESPONSE REGULATOR receiver
AWV81_RS07440	COG3850	Histidine kinase
AWV81_RS07440	COG5002	protein histidine kinase activity
AWV81_RS07445	COG3212	peptidase
AWV81_RS07450	COG3212	peptidase
AWV81_RS07470	COG2239	Acts as a magnesium transporter
AWV81_RS07475	COG0789	Transcriptional regulator
AWV81_RS07490	COG1846	Transcriptional regulator
AWV81_RS07495	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWV81_RS07500	COG0726	polysaccharide deacetylase
AWV81_RS07505	COG1408	metallophosphoesterase
AWV81_RS07515	COG0463	Glycosyl transferase, family 2
AWV81_RS07520	COG3285	dna ligase
AWV81_RS07520	COG1793	dna ligase
AWV81_RS07525	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AWV81_RS07530	COG3300	MHYT domain
AWV81_RS07530	COG5001	Diguanylate cyclase
AWV81_RS07535	COG0586	Pfam SNARE associated Golgi protein
AWV81_RS07540	COG0861	Integral membrane protein TerC family
AWV81_RS07545	COG1191	sigma factor activity
AWV81_RS07565	COG0501	Belongs to the peptidase M48B family
AWV81_RS07570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWV81_RS07595	COG3594	Acyltransferase
AWV81_RS07600	COG5002	protein histidine kinase activity
AWV81_RS07605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AWV81_RS07615	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AWV81_RS07620	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AWV81_RS07625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWV81_RS07630	COG0436	Aminotransferase
AWV81_RS07635	COG1850	ribulose-bisphosphate carboxylase activity
AWV81_RS07640	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AWV81_RS07645	COG0235	Class ii aldolase
AWV81_RS07650	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AWV81_RS07655	COG3339	Conserved Protein
AWV81_RS07670	COG3852	Histidine kinase
AWV81_RS07675	COG1846	Transcriptional regulator
AWV81_RS07680	COG1360	Flagellar Motor Protein
AWV81_RS07685	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AWV81_RS07690	COG0542	response to heat
AWV81_RS07695	COG3949	Membrane
AWV81_RS07700	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AWV81_RS07705	COG0720	synthase
AWV81_RS07710	COG0602	queuosine metabolic process
AWV81_RS07715	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AWV81_RS07725	COG4873	Protein conserved in bacteria
AWV81_RS07740	COG3773	Cell wall hydrolase
AWV81_RS07745	COG2244	polysaccharide biosynthetic process
AWV81_RS07750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_RS07755	COG2217	Heavy metal translocating P-type atpase
AWV81_RS07765	COG0006	proline dipeptidase activity
AWV81_RS07775	COG1609	Transcriptional regulator
AWV81_RS07780	COG3711	transcriptional antiterminator
AWV81_RS07785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_RS07785	COG2190	(PTS) system
AWV81_RS07785	COG1263	PTS System
AWV81_RS07790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_RS07795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AWV81_RS07805	COG1533	DNA photolyase activity
AWV81_RS07810	COG0456	acetyltransferase
AWV81_RS07815	COG0840	transmembrane signaling receptor activity
AWV81_RS07820	COG2084	Dehydrogenase
AWV81_RS07825	COG3328	transposase activity
AWV81_RS07830	COG2340	Cysteine-rich secretory protein family
AWV81_RS07835	COG0768	penicillin binding
AWV81_RS07840	COG4191	Histidine kinase
AWV81_RS07845	COG0436	Aminotransferase
AWV81_RS07855	COG0835	chemotaxis
AWV81_RS07855	COG0784	Response regulator, receiver
AWV81_RS07865	COG2814	Major facilitator Superfamily
AWV81_RS07870	COG1376	ErfK ybiS ycfS ynhG family protein
AWV81_RS07875	COG1408	metallophosphoesterase
AWV81_RS07880	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS07885	COG2200	EAL domain
AWV81_RS07895	COG4703	Protein of unknown function (DUF1797)
AWV81_RS07900	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AWV81_RS07910	COG0517	IMP dehydrogenase activity
AWV81_RS07915	COG0583	DNA-binding transcription factor activity
AWV81_RS07920	COG0716	FMN binding
AWV81_RS07930	COG0716	FMN binding
AWV81_RS07935	COG2171	N-acyltransferase activity
AWV81_RS07940	COG1473	amidohydrolase
AWV81_RS07950	COG0668	transmembrane transport
AWV81_RS07955	COG0450	alkyl hydroperoxide reductase
AWV81_RS07960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_RS07970	COG2801	Transposase and inactivated derivatives
AWV81_RS07985	COG0746	molybdenum cofactor guanylyltransferase activity
AWV81_RS07990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWV81_RS07995	COG0303	'Molybdopterin
AWV81_RS08000	COG1763	Mo-molybdopterin cofactor biosynthetic process
AWV81_RS08005	COG0314	molybdopterin synthase activity
AWV81_RS08010	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AWV81_RS08020	COG1132	(ABC) transporter
AWV81_RS08030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWV81_RS08035	COG1136	(ABC) transporter
AWV81_RS08040	COG0577	efflux transmembrane transporter activity
AWV81_RS08045	COG1349	DNA-binding transcription factor activity
AWV81_RS08050	COG1105	Belongs to the carbohydrate kinase PfkB family
AWV81_RS08055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWV81_RS08055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWV81_RS08055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_RS08060	COG0681	Belongs to the peptidase S26 family
AWV81_RS08070	COG0488	(ABC) transporter
AWV81_RS08075	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AWV81_RS08080	COG2309	aminopeptidase activity
AWV81_RS08090	COG1077	Cell shape determining protein MreB Mrl
AWV81_RS08095	COG2002	toxin-antitoxin pair type II binding
AWV81_RS08100	COG3852	Histidine kinase
AWV81_RS08105	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AWV81_RS08105	COG2105	PFAM AIG2 family protein
AWV81_RS08110	COG0569	domain protein
AWV81_RS08115	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AWV81_RS08120	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AWV81_RS08125	COG5503	Protein of unknown function (DUF1447)
AWV81_RS08130	COG0561	phosphatase activity
AWV81_RS08135	COG0242	peptide deformylase activity
AWV81_RS08150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWV81_RS08155	COG0022	dehydrogenase e1 component
AWV81_RS08160	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWV81_RS08165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWV81_RS08170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_RS08175	COG1982	Orn Lys Arg decarboxylase major
AWV81_RS08180	COG4476	Belongs to the UPF0223 family
AWV81_RS08185	COG4493	Belongs to the UPF0637 family
AWV81_RS08195	COG0483	inositol monophosphate 1-phosphatase activity
AWV81_RS08210	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AWV81_RS08255	COG1217	gtp-binding protein TYPA
AWV81_RS08265	COG4896	Protein conserved in bacteria
AWV81_RS08275	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AWV81_RS08280	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AWV81_RS08285	COG2066	Belongs to the glutaminase family
AWV81_RS08290	COG4838	Belongs to the UPF0358 family
AWV81_RS08295	COG0772	Belongs to the SEDS family
AWV81_RS08300	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AWV81_RS08305	COG1612	heme a metabolic process
AWV81_RS08310	COG0109	protoheme IX farnesyltransferase activity
AWV81_RS08315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWV81_RS08315	COG2010	Cytochrome c
AWV81_RS08320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWV81_RS08325	COG1845	cytochrome c oxidase, subunit III
AWV81_RS08330	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AWV81_RS08335	COG3336	cytochrome c oxidase
AWV81_RS08345	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AWV81_RS08350	COG2340	Cysteine-rich secretory protein family
AWV81_RS08365	COG3679	Belongs to the UPF0342 family
AWV81_RS08370	COG4471	UPF0298 protein
AWV81_RS08375	COG0742	ribosomal rna small subunit methyltransferase
AWV81_RS08380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AWV81_RS08385	COG3314	Sporulation integral membrane protein YlbJ
AWV81_RS08390	COG1752	Esterase of the alpha-beta hydrolase superfamily
AWV81_RS08395	COG3480	Lon protease (S16) C-terminal proteolytic domain
AWV81_RS08400	COG1323	Belongs to the UPF0348 family
AWV81_RS08410	COG1399	metal-binding, possibly nucleic acid-binding protein
AWV81_RS08425	COG0454	-acetyltransferase
AWV81_RS08430	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AWV81_RS08435	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AWV81_RS08440	COG2001	Belongs to the MraZ family
AWV81_RS08445	COG0275	rRNA processing
AWV81_RS08450	COG4839	cell division protein FtsL
AWV81_RS08455	COG0768	penicillin binding
AWV81_RS08465	COG0768	penicillin binding
AWV81_RS08475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AWV81_RS08485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWV81_RS08490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AWV81_RS08495	COG0772	Belongs to the SEDS family
AWV81_RS08500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWV81_RS08505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AWV81_RS08510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AWV81_RS08515	COG3879	Bacterial protein of unknown function (DUF881)
AWV81_RS08520	COG3879	Bacterial protein of unknown function (DUF881)
AWV81_RS08525	COG3856	small basic protein
AWV81_RS08530	COG0849	cell division
AWV81_RS08535	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AWV81_RS08540	COG1404	Belongs to the peptidase S8 family
AWV81_RS08540	COG4412	M6 family metalloprotease domain protein
AWV81_RS08550	COG1191	sigma factor activity
AWV81_RS08555	COG1191	sigma factor activity
AWV81_RS08560	COG1119	ATPase activity
AWV81_RS08565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWV81_RS08570	COG1873	PFAM PRC-barrel domain
AWV81_RS08575	COG1496	oxidoreductase activity
AWV81_RS08580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AWV81_RS08585	COG1799	cell septum assembly
AWV81_RS08590	COG0762	integral membrane protein
AWV81_RS08595	COG2302	S4 RNA-binding domain
AWV81_RS08600	COG3599	regulation of cell shape
AWV81_RS08605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AWV81_RS08610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AWV81_RS08615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AWV81_RS08620	COG0564	pseudouridine synthase activity
AWV81_RS08625	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AWV81_RS08630	COG2233	PERMEase
AWV81_RS08635	COG0540	Belongs to the ATCase OTCase family
AWV81_RS08640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWV81_RS08645	COG0505	Belongs to the CarA family
AWV81_RS08650	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWV81_RS08655	COG0543	2 iron, 2 sulfur cluster binding
AWV81_RS08660	COG0167	dihydroorotate dehydrogenase activity
AWV81_RS08665	COG0284	orotidine-5'-phosphate decarboxylase activity
AWV81_RS08670	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWV81_RS08675	COG0175	sulfate reduction
AWV81_RS08680	COG0306	phosphate transporter
AWV81_RS08685	COG2046	Belongs to the sulfate adenylyltransferase family
AWV81_RS08690	COG0529	Catalyzes the synthesis of activated sulfate
AWV81_RS08695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWV81_RS08700	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AWV81_RS08705	COG1648	precorrin-2 dehydrogenase activity
AWV81_RS08715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWV81_RS08720	COG1561	YicC-like family, N-terminal region
AWV81_RS08730	COG0194	GDP metabolic process
AWV81_RS08735	COG1758	RNA polymerase activity
AWV81_RS08740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWV81_RS08745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWV81_RS08750	COG0242	peptide deformylase activity
AWV81_RS08755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AWV81_RS08760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWV81_RS08760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWV81_RS08765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AWV81_RS08770	COG0631	protein serine/threonine phosphatase activity
AWV81_RS08775	COG0515	serine threonine protein kinase
AWV81_RS08775	COG2815	serine threonine protein kinase
AWV81_RS08780	COG1162	GTPase activity
AWV81_RS08785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AWV81_RS08790	COG1564	THIamine pyrophosphokinase
AWV81_RS08800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AWV81_RS08805	COG1302	Protein conserved in bacteria
AWV81_RS08810	COG1461	Dihydroxyacetone kinase
AWV81_RS08815	COG1760	l-serine dehydratase
AWV81_RS08820	COG1760	l-serine dehydratase
AWV81_RS08825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWV81_RS08830	COG2050	protein possibly involved in aromatic compounds catabolism
AWV81_RS08830	COG1349	DNA-binding transcription factor activity
AWV81_RS08835	COG0416	fatty acid biosynthetic process
AWV81_RS08840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AWV81_RS08845	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS08855	COG0571	ribonuclease III activity
AWV81_RS08860	COG1196	nuclear chromosome segregation
AWV81_RS08865	COG0552	protein localization to endoplasmic reticulum
AWV81_RS08875	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AWV81_RS08880	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AWV81_RS08885	COG0228	four-way junction DNA binding
AWV81_RS08890	COG1837	Belongs to the UPF0109 family
AWV81_RS08900	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AWV81_RS08905	COG0336	Belongs to the RNA methyltransferase TrmD family
AWV81_RS08910	COG0335	large ribosomal subunit rRNA binding
AWV81_RS08915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AWV81_RS08920	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWV81_RS08930	COG2257	FlhB HrpN YscU SpaS Family
AWV81_RS08935	COG0045	succinate-CoA ligase (ADP-forming) activity
AWV81_RS08940	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AWV81_RS08945	COG0758	DNA mediated transformation
AWV81_RS08950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWV81_RS08955	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AWV81_RS08960	COG4974	Belongs to the 'phage' integrase family
AWV81_RS08965	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AWV81_RS08970	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AWV81_RS08975	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AWV81_RS08980	COG1815	bacterial-type flagellum-dependent cell motility
AWV81_RS08985	COG1558	bacterial-type flagellum-dependent cell motility
AWV81_RS08990	COG1677	Flagellar hook-basal body complex protein FliE
AWV81_RS09000	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AWV81_RS09005	COG1317	bacterial-type flagellum organization
AWV81_RS09010	COG1157	protein secretion by the type III secretion system
AWV81_RS09015	COG2882	bacterial-type flagellum organization
AWV81_RS09020	COG3334	PFAM MgtE intracellular
AWV81_RS09025	COG3144	bacterial-type flagellum assembly
AWV81_RS09030	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AWV81_RS09035	COG4786	Flagellar basal body rod
AWV81_RS09040	COG1582	Flagellar protein (FlbD)
AWV81_RS09045	COG1580	Controls the rotational direction of flagella during chemotaxis
AWV81_RS09050	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AWV81_RS09055	COG1776	CheC inhibitor of MCP methylation
AWV81_RS09055	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AWV81_RS09060	COG2201	protein-glutamate methylesterase activity
AWV81_RS09065	COG3190	flagellar
AWV81_RS09070	COG1338	Plays a role in the flagellum-specific transport system
AWV81_RS09075	COG1987	bacterial-type flagellum assembly
AWV81_RS09080	COG1684	flagellar biosynthetic protein fliR
AWV81_RS09085	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AWV81_RS09090	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AWV81_RS09095	COG1419	protein localization to endoplasmic reticulum
AWV81_RS09100	COG0455	bacterial-type flagellum organization
AWV81_RS09105	COG2201	protein-glutamate methylesterase activity
AWV81_RS09110	COG2198	Histidine kinase
AWV81_RS09110	COG0643	Histidine kinase
AWV81_RS09115	COG0835	chemotaxis
AWV81_RS09125	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AWV81_RS09130	COG1191	sigma factor activity
AWV81_RS09140	COG0052	Belongs to the universal ribosomal protein uS2 family
AWV81_RS09145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AWV81_RS09150	COG0528	UMP kinase activity
AWV81_RS09155	COG0233	cytoplasmic translational termination
AWV81_RS09160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AWV81_RS09165	COG4589	Belongs to the CDS family
AWV81_RS09170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AWV81_RS09175	COG0750	zinc metalloprotease
AWV81_RS09180	COG0442	prolyl-tRNA aminoacylation
AWV81_RS09185	COG2176	DNA-directed DNA polymerase activity
AWV81_RS09190	COG0779	Required for maturation of 30S ribosomal subunits
AWV81_RS09195	COG0195	Participates in both transcription termination and antitermination
AWV81_RS09200	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AWV81_RS09205	COG1358	cellular component organization or biogenesis
AWV81_RS09210	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AWV81_RS09215	COG1550	Protein conserved in bacteria
AWV81_RS09220	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AWV81_RS09225	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AWV81_RS09230	COG0196	riboflavin kinase activity
AWV81_RS09235	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AWV81_RS09240	COG1185	polyribonucleotide nucleotidyltransferase activity
AWV81_RS09245	COG0726	polysaccharide deacetylase
AWV81_RS09250	COG0612	Peptidase, M16
AWV81_RS09255	COG1873	PFAM PRC-barrel domain
AWV81_RS09265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWV81_RS09270	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWV81_RS09275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AWV81_RS09280	COG0527	aspartate kinase activity
AWV81_RS09285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWV81_RS09290	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AWV81_RS09295	COG0740	serine-type endopeptidase activity
AWV81_RS09305	COG4980	gas vesicle protein
AWV81_RS09305	COG1674	ftsk spoiiie
AWV81_RS09310	COG2188	Transcriptional regulator
AWV81_RS09315	COG2814	Major facilitator Superfamily
AWV81_RS09320	COG0612	Peptidase, M16
AWV81_RS09325	COG0612	Peptidase, M16
AWV81_RS09330	COG0300	oxidoreductase activity
AWV81_RS09345	COG1426	Protein conserved in bacteria
AWV81_RS09350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AWV81_RS09355	COG1058	Belongs to the CinA family
AWV81_RS09355	COG1546	Belongs to the CinA family
AWV81_RS09360	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AWV81_RS09365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AWV81_RS09370	COG1418	mRNA catabolic process
AWV81_RS09375	COG1692	metallophosphoesterase
AWV81_RS09380	COG2359	stage V sporulation protein S
AWV81_RS09385	COG1063	alcohol dehydrogenase
AWV81_RS09390	COG0156	8-amino-7-oxononanoate synthase activity
AWV81_RS09395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWV81_RS09400	COG4550	Control of competence regulator ComK, YlbF/YmcA
AWV81_RS09410	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWV81_RS09415	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AWV81_RS09520	COG3226	Transcriptional regulator
AWV81_RS09530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWV81_RS09535	COG1404	Belongs to the peptidase S8 family
AWV81_RS09545	COG4195	phage-related replication protein
AWV81_RS09550	COG1764	response to oxidative stress
AWV81_RS09555	COG2076	Multidrug Resistance protein
AWV81_RS09560	COG2076	Multidrug Resistance protein
AWV81_RS09575	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AWV81_RS09580	COG1923	regulation of RNA biosynthetic process
AWV81_RS09595	COG1780	Probably involved in ribonucleotide reductase function
AWV81_RS09600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWV81_RS09605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWV81_RS09610	COG4112	unkown
AWV81_RS09615	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWV81_RS09620	COG0464	growth
AWV81_RS09630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AWV81_RS09635	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AWV81_RS09640	COG0789	Transcriptional regulator
AWV81_RS09645	COG0174	glutamine synthetase
AWV81_RS09650	COG4974	Belongs to the 'phage' integrase family
AWV81_RS09670	COG3645	SOS response
AWV81_RS09670	COG3646	Phage regulatory protein
AWV81_RS09815	COG3953	SLT domain
AWV81_RS09815	COG5412	phage tail tape measure protein
AWV81_RS09855	COG1388	LysM domain
AWV81_RS09855	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWV81_RS09855	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_RS09865	COG5444	nuclease activity
AWV81_RS09900	COG4282	regulation of fungal-type cell wall biogenesis
AWV81_RS09920	COG3328	transposase activity
AWV81_RS09935	COG3655	Transcriptional regulator
AWV81_RS09960	COG0135	phosphoribosylanthranilate isomerase activity
AWV81_RS09965	COG2211	Major facilitator Superfamily
AWV81_RS09980	COG3507	Belongs to the glycosyl hydrolase 43 family
AWV81_RS09985	COG1940	carbohydrate kinase activity
AWV81_RS09990	COG2115	Belongs to the xylose isomerase family
AWV81_RS09995	COG1070	Carbohydrate kinase
AWV81_RS10000	COG3328	transposase activity
AWV81_RS10005	COG1525	nuclease
AWV81_RS10010	COG2814	Major facilitator Superfamily
AWV81_RS10015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AWV81_RS10030	COG0756	dUTP diphosphatase activity
AWV81_RS10070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWV81_RS10090	COG3832	glyoxalase III activity
AWV81_RS10135	COG4195	phage-related replication protein
AWV81_RS10145	COG0346	lactoylglutathione lyase activity
AWV81_RS10155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AWV81_RS10160	COG1388	LysM domain
AWV81_RS10165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AWV81_RS10170	COG4224	UPF0291 protein
AWV81_RS10175	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AWV81_RS10185	COG3763	UPF0154 protein
AWV81_RS10195	COG0785	Cytochrome C biogenesis protein
AWV81_RS10200	COG2201	protein-glutamate methylesterase activity
AWV81_RS10205	COG4846	Membrane protein involved in cytochrome C biogenesis
AWV81_RS10215	COG0071	Belongs to the small heat shock protein (HSP20) family
AWV81_RS10230	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AWV81_RS10235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_RS10255	COG0824	Thioesterase
AWV81_RS10265	COG4841	protein insertion into membrane
AWV81_RS10270	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AWV81_RS10275	COG1832	CoA-binding protein
AWV81_RS10280	COG0187	DNA topoisomerase II activity
AWV81_RS10285	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWV81_RS10300	COG1115	amino acid carrier protein
AWV81_RS10305	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AWV81_RS10315	COG5520	Belongs to the glycosyl hydrolase 30 family
AWV81_RS10325	COG2246	polysaccharide biosynthetic process
AWV81_RS10330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AWV81_RS10335	COG0586	Pfam SNARE associated Golgi protein
AWV81_RS10340	COG2404	hydrolase activity, acting on ester bonds
AWV81_RS10345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AWV81_RS10350	COG1024	Enoyl-CoA hydratase
AWV81_RS10355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWV81_RS10360	COG0511	ligase activity, forming carbon-carbon bonds
AWV81_RS10365	COG0439	Biotin carboxylase
AWV81_RS10370	COG0318	PFAM AMP-dependent synthetase and ligase
AWV81_RS10375	COG1960	acyl-CoA dehydrogenase activity
AWV81_RS10385	COG1649	PFAM Uncharacterised BCR, COG1649
AWV81_RS10400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWV81_RS10405	COG2027	D-alanyl-D-alanine carboxypeptidase
AWV81_RS10410	COG2017	converts alpha-aldose to the beta-anomer
AWV81_RS10415	COG0534	Mate efflux family protein
AWV81_RS10430	COG2801	Transposase and inactivated derivatives
AWV81_RS10440	COG0582	viral genome integration into host DNA
AWV81_RS10445	COG0166	Belongs to the GPI family
AWV81_RS10450	COG0405	Gamma-glutamyltransferase
AWV81_RS10455	COG0583	DNA-binding transcription factor activity
AWV81_RS10460	COG0604	alcohol dehydrogenase
AWV81_RS10465	COG0493	'glutamate synthase
AWV81_RS10470	COG0067	glutamate synthase
AWV81_RS10470	COG0069	glutamate synthase activity
AWV81_RS10470	COG0070	glutamate synthase
AWV81_RS10475	COG0583	DNA-binding transcription factor activity
AWV81_RS10480	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AWV81_RS10485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWV81_RS10490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWV81_RS10500	COG0300	oxidoreductase activity
AWV81_RS10505	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AWV81_RS10515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_RS10530	COG1131	(ABC) transporter
AWV81_RS10540	COG2814	Major facilitator Superfamily
AWV81_RS10545	COG3328	transposase activity
AWV81_RS10570	COG2801	Transposase and inactivated derivatives
AWV81_RS10590	COG3328	transposase activity
AWV81_RS10645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWV81_RS10650	COG2226	methyltransferase
AWV81_RS10655	COG2211	Major facilitator Superfamily
AWV81_RS10665	COG3328	transposase activity
AWV81_RS10690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_RS10710	COG5444	nuclease activity
AWV81_RS10715	COG4282	regulation of fungal-type cell wall biogenesis
AWV81_RS10720	COG1231	oxidoreductase activity
AWV81_RS10725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWV81_RS10730	COG0662	Cupin 2, conserved barrel domain protein
AWV81_RS10730	COG2207	Transcriptional regulator
AWV81_RS10735	COG0456	acetyltransferase
AWV81_RS10740	COG1309	transcriptional regulator
AWV81_RS10745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWV81_RS10750	COG3708	Transcriptional regulator
AWV81_RS10755	COG2378	regulation of single-species biofilm formation
AWV81_RS10765	COG0640	Transcriptional regulator
AWV81_RS10770	COG0741	lytic transglycosylase activity
AWV81_RS10775	COG2322	membrane
AWV81_RS10790	COG1619	proteins homologs of microcin C7 resistance protein MccF
AWV81_RS10795	COG3239	Fatty acid desaturase
AWV81_RS10800	COG4585	Histidine kinase
AWV81_RS10805	COG2197	response regulator
AWV81_RS10810	COG1388	LysM domain
AWV81_RS10810	COG3584	3D domain protein
AWV81_RS10815	COG0514	ATP-dependent DNA helicase (RecQ)
AWV81_RS10830	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AWV81_RS10835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AWV81_RS10850	COG0071	Belongs to the small heat shock protein (HSP20) family
AWV81_RS10875	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_RS10880	COG1657	PFAM Prenyltransferase squalene oxidase
AWV81_RS10885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AWV81_RS10890	COG0733	neurotransmitter:sodium symporter activity
AWV81_RS10895	COG0385	Bile acid
AWV81_RS10900	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWV81_RS10905	COG0567	Dehydrogenase, E1 component
AWV81_RS10910	COG4548	von Willebrand factor, type A
AWV81_RS10915	COG0714	Associated with various cellular activities
AWV81_RS10920	COG2032	superoxide dismutase activity
AWV81_RS10925	COG1388	LysM domain
AWV81_RS10925	COG0791	NLP P60 protein
AWV81_RS10930	COG1819	glycosyl
AWV81_RS10935	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AWV81_RS10940	COG0534	Mate efflux family protein
AWV81_RS10945	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_RS10950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AWV81_RS10955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AWV81_RS10965	COG2962	Rard protein
AWV81_RS10985	COG1942	4-Oxalocrotonate Tautomerase
AWV81_RS10990	COG1733	regulation of RNA biosynthetic process
AWV81_RS10995	COG0778	Nitroreductase
AWV81_RS11005	COG2801	Transposase and inactivated derivatives
AWV81_RS11010	COG0400	carboxylic ester hydrolase activity
AWV81_RS11025	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWV81_RS11030	COG0793	Belongs to the peptidase S41A family
AWV81_RS11030	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_RS11035	COG2226	methyltransferase
AWV81_RS11045	COG1876	peptidase activity
AWV81_RS11050	COG0813	purine-nucleoside phosphorylase activity
AWV81_RS11065	COG0671	phosphoesterase, PA-phosphatase related
AWV81_RS11090	COG4479	Belongs to the UPF0346 family
AWV81_RS11100	COG1509	lysine 2,3-aminomutase activity
AWV81_RS11105	COG0456	acetyltransferase
AWV81_RS11110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWV81_RS11115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AWV81_RS11120	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AWV81_RS11125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AWV81_RS11140	COG0456	acetyltransferase
AWV81_RS11145	COG0463	Glycosyl transferase, family 2
AWV81_RS11160	COG4641	Protein conserved in bacteria
AWV81_RS11165	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
AWV81_RS11170	COG1086	Polysaccharide biosynthesis protein
AWV81_RS11175	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWV81_RS11180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWV81_RS11185	COG1846	Transcriptional regulator
AWV81_RS11190	COG0534	Mate efflux family protein
AWV81_RS11200	COG4698	Protein conserved in bacteria
AWV81_RS11205	COG2755	lipolytic protein G-D-S-L family
AWV81_RS11210	COG1999	signal sequence binding
AWV81_RS11225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AWV81_RS11230	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AWV81_RS11235	COG1272	protein, Hemolysin III
AWV81_RS11240	COG0204	Acyl-transferase
AWV81_RS11245	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AWV81_RS11250	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AWV81_RS11260	COG2521	methyltransferase
AWV81_RS11260	COG2136	Putative SAM-dependent methyltransferase
AWV81_RS11270	COG0129	dihydroxy-acid dehydratase activity
AWV81_RS11275	COG1413	lyase activity
AWV81_RS11280	COG1418	mRNA catabolic process
AWV81_RS11285	COG0386	Belongs to the glutathione peroxidase family
AWV81_RS11290	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AWV81_RS11295	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWV81_RS11300	COG1278	Cold shock
AWV81_RS11320	COG0328	RNA-DNA hybrid ribonuclease activity
AWV81_RS11325	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AWV81_RS11330	COG0328	RNA-DNA hybrid ribonuclease activity
AWV81_RS11340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWV81_RS11360	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AWV81_RS11365	COG1755	Isoprenylcysteine carboxyl methyltransferase
AWV81_RS11370	COG3424	synthase
AWV81_RS11375	COG2233	PERMEase
AWV81_RS11380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWV81_RS11385	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AWV81_RS11395	COG0800	Aldolase
AWV81_RS11400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWV81_RS11405	COG1609	Transcriptional regulator
AWV81_RS11410	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AWV81_RS11415	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS11420	COG1199	ATP-dependent helicase activity
AWV81_RS11430	COG0116	Belongs to the methyltransferase superfamily
AWV81_RS11445	COG4474	Belongs to the UPF0398 family
AWV81_RS11455	COG3359	exonuclease
AWV81_RS11460	COG1111	helicase
AWV81_RS11460	COG1205	dead DEAH box helicase
AWV81_RS11465	COG2190	(PTS) system
AWV81_RS11470	COG0071	Belongs to the small heat shock protein (HSP20) family
AWV81_RS11505	COG3331	DNA recombination
AWV81_RS11510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWV81_RS11510	COG4499	WXG100 protein secretion system (Wss), protein YukC
AWV81_RS11520	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AWV81_RS11525	COG3935	DnaD domain protein
AWV81_RS11530	COG0017	Asparaginyl-tRNA synthetase
AWV81_RS11535	COG0436	Aminotransferase
AWV81_RS11540	COG5353	protein conserved in bacteria
AWV81_RS11550	COG1199	ATP-dependent helicase activity
AWV81_RS11550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AWV81_RS11555	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AWV81_RS11560	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AWV81_RS11565	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AWV81_RS11570	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AWV81_RS11570	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AWV81_RS11575	COG0617	tRNA 3'-terminal CCA addition
AWV81_RS11580	COG0438	transferase activity, transferring glycosyl groups
AWV81_RS11585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AWV81_RS11590	COG1803	Methylglyoxal synthase
AWV81_RS11595	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AWV81_RS11600	COG1694	Mazg nucleotide pyrophosphohydrolase
AWV81_RS11605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWV81_RS11615	COG4347	Protein of unknown function (DUF1405)
AWV81_RS11620	COG2010	Cytochrome c
AWV81_RS11620	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWV81_RS11625	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWV81_RS11630	COG0723	plastoquinol--plastocyanin reductase activity
AWV81_RS11640	COG5582	Belongs to the UPF0302 family
AWV81_RS11645	COG0457	Tetratricopeptide repeat
AWV81_RS11650	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AWV81_RS11655	COG0287	Prephenate dehydrogenase
AWV81_RS11670	COG0133	tryptophan synthase activity
AWV81_RS11675	COG0135	phosphoribosylanthranilate isomerase activity
AWV81_RS11685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWV81_RS11690	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWV81_RS11695	COG4401	Chorismate mutase type I
AWV81_RS11700	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AWV81_RS11705	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AWV81_RS11710	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AWV81_RS11720	COG0105	UTP biosynthetic process
AWV81_RS11725	COG0142	geranyltranstransferase activity
AWV81_RS11730	COG2226	methyltransferase
AWV81_RS11735	COG0142	geranyltranstransferase activity
AWV81_RS11745	COG0302	gtp cyclohydrolase
AWV81_RS11750	COG0776	regulation of translation
AWV81_RS11755	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AWV81_RS11770	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AWV81_RS11775	COG1160	GTP binding
AWV81_RS11800	COG1304	FMN binding
AWV81_RS11805	COG0539	negative regulation of cytoplasmic translation
AWV81_RS11810	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AWV81_RS11820	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AWV81_RS11825	COG2959	enzyme of heme biosynthesis
AWV81_RS11830	COG3773	Cell wall hydrolase
AWV81_RS11830	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_RS11835	COG2339	peptidase activity
AWV81_RS11840	COG0492	ferredoxin-NADP+ reductase activity
AWV81_RS11845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWV81_RS11850	COG4862	establishment of competence for transformation
AWV81_RS11855	COG1408	metallophosphoesterase
AWV81_RS11865	COG1388	LysM domain
AWV81_RS11870	COG1266	CAAX protease self-immunity
AWV81_RS11875	COG0514	ATP-dependent DNA helicase (RecQ)
AWV81_RS11880	COG4955	Helix-turn-helix domain
AWV81_RS11885	COG1141	Ferredoxin
AWV81_RS11890	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AWV81_RS11895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWV81_RS11900	COG0710	3-dehydroquinate dehydratase activity
AWV81_RS11910	COG1595	DNA-templated transcription, initiation
AWV81_RS11915	COG5002	protein histidine kinase activity
AWV81_RS11920	COG0745	RESPONSE REGULATOR receiver
AWV81_RS11925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AWV81_RS11930	COG1333	cytochrome c biogenesis protein
AWV81_RS11935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_RS11940	COG1187	pseudouridine synthase activity
AWV81_RS11945	COG0700	Nucleoside recognition
AWV81_RS11950	COG2715	membrane protein required for spore maturation
AWV81_RS11955	COG1686	Belongs to the peptidase S11 family
AWV81_RS11965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AWV81_RS11970	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AWV81_RS11975	COG1547	Domain of unknown function (DUF309)
AWV81_RS11980	COG0456	acetyltransferase
AWV81_RS11985	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AWV81_RS11990	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWV81_RS11990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWV81_RS11995	COG0307	riboflavin synthase, alpha
AWV81_RS12000	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWV81_RS12000	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWV81_RS12010	COG0681	Belongs to the peptidase S26 family
AWV81_RS12020	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AWV81_RS12030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWV81_RS12035	COG2433	Pfam Transposase IS66
AWV81_RS12065	COG3328	transposase activity
AWV81_RS12115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWV81_RS12125	COG4086	secreted protein
AWV81_RS12130	COG0019	diaminopimelate decarboxylase activity
AWV81_RS12135	COG0697	spore germination
AWV81_RS12150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWV81_RS12170	COG1191	sigma factor activity
AWV81_RS12175	COG2172	sigma factor antagonist activity
AWV81_RS12180	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_RS12185	COG1686	Belongs to the peptidase S11 family
AWV81_RS12190	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AWV81_RS12195	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AWV81_RS12200	COG4974	Belongs to the 'phage' integrase family
AWV81_RS12210	COG0735	belongs to the Fur family
AWV81_RS12215	COG1300	Membrane
AWV81_RS12225	COG0281	malic enzyme
AWV81_RS12230	COG1757	Na H antiporter
AWV81_RS12235	COG1027	Aspartate ammonia-lyase
AWV81_RS12240	COG0252	asparaginase activity
AWV81_RS12245	COG1396	sequence-specific DNA binding
AWV81_RS12250	COG1379	DNA repair
AWV81_RS12255	COG0494	nUDIX hydrolase
AWV81_RS12265	COG0667	Aldo Keto reductase
AWV81_RS12275	COG1073	alpha beta
AWV81_RS12285	COG4918	Iron-sulphur cluster biosynthesis
AWV81_RS12290	COG0456	acetyltransferase
AWV81_RS12290	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AWV81_RS12295	COG2329	Antibiotic biosynthesis monooxygenase
AWV81_RS12300	COG0456	acetyltransferase
AWV81_RS12310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWV81_RS12320	COG2211	Major facilitator Superfamily
AWV81_RS12330	COG0346	lactoylglutathione lyase activity
AWV81_RS12335	COG1072	(Pantothenic acid kinase))
AWV81_RS12340	COG3048	D-serine ammonia-lyase activity
AWV81_RS12345	COG0300	oxidoreductase activity
AWV81_RS12350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWV81_RS12355	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWV81_RS12360	COG4187	Peptidase family M20/M25/M40
AWV81_RS12365	COG1902	pentaerythritol trinitrate reductase activity
AWV81_RS12375	COG0511	ligase activity, forming carbon-carbon bonds
AWV81_RS12380	COG0439	Biotin carboxylase
AWV81_RS12385	COG1302	Protein conserved in bacteria
AWV81_RS12390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWV81_RS12395	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AWV81_RS12400	COG1570	exodeoxyribonuclease VII activity
AWV81_RS12405	COG1722	exodeoxyribonuclease VII activity
AWV81_RS12410	COG0142	geranyltranstransferase activity
AWV81_RS12415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AWV81_RS12420	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AWV81_RS12425	COG1438	arginine binding
AWV81_RS12430	COG0497	DNA recombination
AWV81_RS12435	COG0750	zinc metalloprotease
AWV81_RS12445	COG0745	RESPONSE REGULATOR receiver
AWV81_RS12455	COG1902	pentaerythritol trinitrate reductase activity
AWV81_RS12470	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWV81_RS12475	COG0584	glycerophosphoryl diester phosphodiesterase
AWV81_RS12480	COG0183	Belongs to the thiolase family
AWV81_RS12485	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWV81_RS12490	COG1960	acyl-CoA dehydrogenase activity
AWV81_RS12495	COG0372	Belongs to the citrate synthase family
AWV81_RS12500	COG2079	MmgE PrpD family protein
AWV81_RS12505	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AWV81_RS12515	COG3829	transcription factor binding
AWV81_RS12515	COG3290	protein histidine kinase activity
AWV81_RS12520	COG0280	phosphate acetyltransferase
AWV81_RS12525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWV81_RS12530	COG3426	butyrate kinase activity
AWV81_RS12535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWV81_RS12540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWV81_RS12545	COG0022	dehydrogenase e1 component
AWV81_RS12550	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWV81_RS12555	COG4978	Transcriptional regulator
AWV81_RS12555	COG0789	Transcriptional regulator
AWV81_RS12565	COG1597	lipid kinase activity
AWV81_RS12575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWV81_RS12580	COG0765	amino acid transport
AWV81_RS12585	COG1126	abc transporter atp-binding protein
AWV81_RS12590	COG4129	membrane
AWV81_RS12595	COG1376	ErfK ybiS ycfS ynhG family protein
AWV81_RS12605	COG0346	lactoylglutathione lyase activity
AWV81_RS12615	COG2195	Cleaves the N-terminal amino acid of tripeptides
AWV81_RS12620	COG3361	conserved protein (COG2071)
AWV81_RS12625	COG0706	membrane insertase activity
AWV81_RS12635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWV81_RS12640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AWV81_RS12645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AWV81_RS12650	COG1234	tRNA 3'-trailer cleavage
AWV81_RS12660	COG0596	Alpha beta hydrolase
AWV81_RS12705	COG3854	ATPases associated with a variety of cellular activities
AWV81_RS12715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AWV81_RS12720	COG0006	proline dipeptidase activity
AWV81_RS12725	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AWV81_RS12735	COG3872	metal-dependent enzyme
AWV81_RS12745	COG1752	Esterase of the alpha-beta hydrolase superfamily
AWV81_RS12750	COG1321	iron dependent repressor
AWV81_RS12755	COG0095	Lipoate-protein ligase
AWV81_RS12760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWV81_RS12765	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWV81_RS12770	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWV81_RS12775	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWV81_RS12780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWV81_RS12795	COG1396	sequence-specific DNA binding
AWV81_RS12805	COG0681	Belongs to the peptidase S26 family
AWV81_RS12830	COG4940	Competence protein ComGF
AWV81_RS12840	COG4970	Tfp pilus assembly protein FimT
AWV81_RS12845	COG4537	Required for transformation and DNA binding
AWV81_RS12850	COG1459	type II secretion system
AWV81_RS12855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AWV81_RS12865	COG0517	IMP dehydrogenase activity
AWV81_RS12870	COG0598	Magnesium transport protein CorA
AWV81_RS12875	COG1253	flavin adenine dinucleotide binding
AWV81_RS12880	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_RS12890	COG1393	Belongs to the ArsC family
AWV81_RS12900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWV81_RS12910	COG0011	TIGRFAM Protein of
AWV81_RS12920	COG2866	Carboxypeptidase
AWV81_RS12925	COG1368	sulfuric ester hydrolase activity
AWV81_RS12930	COG1940	carbohydrate kinase activity
AWV81_RS12935	COG4483	Protein conserved in bacteria
AWV81_RS12940	COG0705	Rhomboid family
AWV81_RS12940	COG0457	Tetratricopeptide repeat
AWV81_RS12950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AWV81_RS12960	COG0438	transferase activity, transferring glycosyl groups
AWV81_RS12975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWV81_RS12980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWV81_RS12985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWV81_RS12990	COG0581	inorganic phosphate transmembrane transporter activity
AWV81_RS12995	COG0573	inorganic phosphate transmembrane transporter activity
AWV81_RS13000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AWV81_RS13005	COG0768	penicillin binding
AWV81_RS13010	COG0477	Major facilitator Superfamily
AWV81_RS13015	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AWV81_RS13020	COG2839	Protein conserved in bacteria
AWV81_RS13025	COG5521	maltodextrose utilization protein MalA
AWV81_RS13030	COG1388	LysM domain
AWV81_RS13035	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AWV81_RS13040	COG4709	membrane
AWV81_RS13045	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AWV81_RS13050	COG0735	belongs to the Fur family
AWV81_RS13055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWV81_RS13065	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AWV81_RS13070	COG0513	Belongs to the DEAD box helicase family
AWV81_RS13080	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AWV81_RS13085	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AWV81_RS13090	COG2384	SAM-dependent methyltransferase
AWV81_RS13095	COG2010	Cytochrome c
AWV81_RS13100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWV81_RS13105	COG0358	DNA primase activity
AWV81_RS13110	COG1671	Belongs to the UPF0178 family
AWV81_RS13115	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AWV81_RS13120	COG0517	IMP dehydrogenase activity
AWV81_RS13125	COG0751	glycine-tRNA ligase activity
AWV81_RS13130	COG0752	glycyl-tRNA synthetase alpha subunit
AWV81_RS13135	COG1381	Involved in DNA repair and RecF pathway recombination
AWV81_RS13145	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AWV81_RS13150	COG0295	cytidine deaminase activity
AWV81_RS13155	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AWV81_RS13160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AWV81_RS13165	COG1480	7TM receptor with intracellular HD hydrolase
AWV81_RS13175	COG1702	phosphate starvation-inducible protein PhoH
AWV81_RS13180	COG0561	phosphatase activity
AWV81_RS13195	COG4864	UPF0365 protein
AWV81_RS13200	COG1030	water channel activity
AWV81_RS13205	COG1610	YqeY-like protein
AWV81_RS13215	COG1283	sodium-dependent phosphate transmembrane transporter activity
AWV81_RS13220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWV81_RS13225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AWV81_RS13230	COG2264	protein methyltransferase activity
AWV81_RS13235	COG0484	heat shock protein binding
AWV81_RS13240	COG0443	Heat shock 70 kDa protein
AWV81_RS13245	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AWV81_RS13250	COG1420	regulation of RNA biosynthetic process
AWV81_RS13255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWV81_RS13260	COG0481	GTPase activity
AWV81_RS13270	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWV81_RS13275	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AWV81_RS13280	COG0268	Binds directly to 16S ribosomal RNA
AWV81_RS13285	COG1466	dna polymerase III delta subunit
AWV81_RS13295	COG2333	competence protein COMEC
AWV81_RS13295	COG0658	competence protein
AWV81_RS13300	COG2131	deaminase
AWV81_RS13305	COG1555	photosystem II stabilization
AWV81_RS13305	COG1596	polysaccharide export
AWV81_RS13310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWV81_RS13315	COG2226	methyltransferase
AWV81_RS13320	COG0799	negative regulation of ribosome biogenesis
AWV81_RS13325	COG1713	HD superfamily hydrolase involved in NAD metabolism
AWV81_RS13330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AWV81_RS13335	COG1534	Rna-binding protein
AWV81_RS13340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWV81_RS13345	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AWV81_RS13350	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AWV81_RS13365	COG2755	lipolytic protein G-D-S-L family
AWV81_RS13370	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWV81_RS13370	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_RS13375	COG0398	Pfam SNARE associated Golgi protein
AWV81_RS13380	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AWV81_RS13390	COG3209	COG3209 Rhs family protein
AWV81_RS13410	COG0114	fumarate hydratase activity
AWV81_RS13415	COG0583	DNA-binding transcription factor activity
AWV81_RS13425	COG0457	Tetratricopeptide repeat
AWV81_RS13535	COG0789	Transcriptional regulator
AWV81_RS13535	COG4978	Transcriptional regulator
AWV81_RS13540	COG2814	Major facilitator Superfamily
AWV81_RS13545	COG0456	acetyltransferase
AWV81_RS13550	COG1253	flavin adenine dinucleotide binding
AWV81_RS13560	COG0697	spore germination
AWV81_RS13565	COG0583	DNA-binding transcription factor activity
AWV81_RS13570	COG2072	flavoprotein involved in K transport
AWV81_RS13575	COG1230	cation diffusion facilitator family transporter
AWV81_RS13580	COG1942	4-Oxalocrotonate Tautomerase
AWV81_RS13585	COG1114	Component of the transport system for branched-chain amino acids
AWV81_RS13590	COG1687	branched-chain amino acid
AWV81_RS13600	COG1522	sequence-specific DNA binding
AWV81_RS13605	COG2732	(Barnase) inhibitor
AWV81_RS13610	COG2124	cytochrome p450
AWV81_RS13625	COG1335	isochorismatase
AWV81_RS13635	COG2318	DinB family
AWV81_RS13645	COG2070	2-Nitropropane dioxygenase
AWV81_RS13650	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWV81_RS13665	COG3443	Belongs to the bacterial solute-binding protein 9 family
AWV81_RS13670	COG1595	DNA-templated transcription, initiation
AWV81_RS13675	COG0667	Aldo Keto reductase
AWV81_RS13680	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_RS13685	COG5566	PFAM Mor transcription activator
AWV81_RS13690	COG0596	Alpha beta hydrolase
AWV81_RS13695	COG4991	sh3 domain protein
AWV81_RS13700	COG4991	sh3 domain protein
AWV81_RS13705	COG0346	lactoylglutathione lyase activity
AWV81_RS13715	COG5577	PFAM Coat F domain
AWV81_RS13720	COG1063	alcohol dehydrogenase
AWV81_RS13730	COG5577	PFAM Coat F domain
AWV81_RS13735	COG0789	Transcriptional regulator
AWV81_RS13745	COG1064	alcohol dehydrogenase
AWV81_RS13750	COG0693	protein deglycase activity
AWV81_RS13755	COG1621	beta-fructofuranosidase activity
AWV81_RS13760	COG3716	PTS system mannose fructose sorbose family IID component
AWV81_RS13765	COG3715	PTS system
AWV81_RS13770	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_RS13775	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_RS13780	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AWV81_RS13780	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AWV81_RS13785	COG1113	amino acid transport
AWV81_RS13790	COG1280	lysine exporter protein (LysE YggA)
AWV81_RS13795	COG1378	Sugar-specific transcriptional regulator TrmB
AWV81_RS13800	COG1595	DNA-templated transcription, initiation
AWV81_RS13825	COG1309	transcriptional regulator
AWV81_RS13830	COG2226	methyltransferase
AWV81_RS13840	COG2116	formate transmembrane transporter activity
AWV81_RS13845	COG5609	conserved protein (DUF2294)
AWV81_RS13850	COG3383	formate dehydrogenase (NAD+) activity
AWV81_RS13855	COG2427	Protein of unknown function (DUF1641)
AWV81_RS13870	COG0626	cystathionine gamma-synthase activity
AWV81_RS13875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWV81_RS13880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AWV81_RS13885	COG2226	methyltransferase
AWV81_RS13900	COG0768	penicillin binding
AWV81_RS13905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AWV81_RS13910	COG0572	uridine kinase
AWV81_RS13915	COG0826	peptidase U32
AWV81_RS13920	COG0826	peptidase U32
AWV81_RS13925	COG4122	O-methyltransferase activity
AWV81_RS13930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWV81_RS13935	COG3906	Belongs to the UPF0473 family
AWV81_RS13940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AWV81_RS13945	COG4472	Bacterial protein of unknown function (DUF965)
AWV81_RS13950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AWV81_RS13955	COG0628	permease
AWV81_RS13960	COG1126	abc transporter atp-binding protein
AWV81_RS13965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWV81_RS13970	COG0765	amino acid transport
AWV81_RS13975	COG0765	amino acid transport
AWV81_RS13990	COG3881	PFAM PRC-barrel domain
AWV81_RS13995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AWV81_RS14000	COG0457	Tetratricopeptide repeat
AWV81_RS14005	COG0482	sulfurtransferase activity
AWV81_RS14010	COG1104	cysteine desulfurase activity
AWV81_RS14015	COG1959	2 iron, 2 sulfur cluster binding
AWV81_RS14020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AWV81_RS14025	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AWV81_RS14035	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AWV81_RS14040	COG0124	histidyl-tRNA synthetase
AWV81_RS14050	COG3103	Sh3 type 3 domain protein
AWV81_RS14050	COG4991	sh3 domain protein
AWV81_RS14050	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWV81_RS14055	COG1490	D-aminoacyl-tRNA deacylase activity
AWV81_RS14060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWV81_RS14065	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWV81_RS14070	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWV81_RS14070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWV81_RS14075	COG5416	Lipopolysaccharide assembly protein A domain
AWV81_RS14080	COG0490	domain, Protein
AWV81_RS14085	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWV81_RS14085	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWV81_RS14095	COG2244	polysaccharide biosynthetic process
AWV81_RS14100	COG2323	membrane
AWV81_RS14110	COG1862	Preprotein translocase
AWV81_RS14115	COG0343	queuine tRNA-ribosyltransferase activity
AWV81_RS14120	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AWV81_RS14130	COG2255	four-way junction helicase activity
AWV81_RS14135	COG0632	four-way junction helicase activity
AWV81_RS14145	COG2814	Major facilitator Superfamily
AWV81_RS14150	COG0673	inositol 2-dehydrogenase activity
AWV81_RS14155	COG2112	serine threonine protein kinase
AWV81_RS14175	COG1115	amino acid carrier protein
AWV81_RS14180	COG0217	transcriptional regulatory protein
AWV81_RS14190	COG1388	LysM domain
AWV81_RS14195	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AWV81_RS14200	COG0157	Belongs to the NadC ModD family
AWV81_RS14205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AWV81_RS14210	COG1104	cysteine desulfurase activity
AWV81_RS14215	COG1827	regulation of RNA biosynthetic process
AWV81_RS14220	COG0077	Prephenate dehydratase
AWV81_RS14225	COG4492	Belongs to the UPF0735 family
AWV81_RS14230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWV81_RS14235	COG3290	protein histidine kinase activity
AWV81_RS14245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AWV81_RS14250	COG2868	ribosomal protein
AWV81_RS14255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AWV81_RS14260	COG1994	Peptidase M50
AWV81_RS14265	COG0739	heme binding
AWV81_RS14270	COG2894	cell division
AWV81_RS14275	COG0850	regulation of cytokinetic process
AWV81_RS14280	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AWV81_RS14290	COG1077	Cell shape determining protein MreB Mrl
AWV81_RS14295	COG2003	Belongs to the UPF0758 family
AWV81_RS14300	COG0424	maF-like protein
AWV81_RS14310	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AWV81_RS14315	COG0285	dihydrofolate synthase activity
AWV81_RS14320	COG0525	valine-tRNA ligase activity
AWV81_RS14330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWV81_RS14335	COG1388	LysM domain
AWV81_RS14340	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWV81_RS14345	COG0113	porphobilinogen synthase activity
AWV81_RS14350	COG1587	Uroporphyrinogen-III synthase
AWV81_RS14355	COG0181	hydroxymethylbilane synthase activity
AWV81_RS14360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AWV81_RS14365	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AWV81_RS14375	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AWV81_RS14380	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AWV81_RS14385	COG1067	ATP-dependent peptidase activity
AWV81_RS14385	COG0470	DNA polymerase III
AWV81_RS14390	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AWV81_RS14395	COG0544	peptidyl-prolyl cis-trans isomerase activity
AWV81_RS14400	COG0457	Tetratricopeptide repeat
AWV81_RS14400	COG1477	protein flavinylation
AWV81_RS14405	COG0066	3-isopropylmalate dehydratase activity
AWV81_RS14410	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWV81_RS14415	COG0473	3-isopropylmalate dehydrogenase activity
AWV81_RS14420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWV81_RS14425	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AWV81_RS14430	COG0440	acetolactate synthase activity
AWV81_RS14435	COG0028	Belongs to the TPP enzyme family
AWV81_RS14455	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AWV81_RS14465	COG2801	Transposase and inactivated derivatives
AWV81_RS14490	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AWV81_RS14515	COG0622	Phosphoesterase
AWV81_RS14520	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AWV81_RS14525	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AWV81_RS14530	COG5401	PFAM Sporulation and spore germination
AWV81_RS14535	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWV81_RS14540	COG1846	Transcriptional regulator
AWV81_RS14545	COG2197	response regulator
AWV81_RS14550	COG0824	Thioesterase
AWV81_RS14555	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AWV81_RS14560	COG1053	succinate dehydrogenase
AWV81_RS14565	COG2009	succinate dehydrogenase
AWV81_RS14575	COG1719	4-vinyl reductase, 4VR
AWV81_RS14580	COG0527	aspartate kinase activity
AWV81_RS14585	COG0322	excinuclease ABC activity
AWV81_RS14590	COG3118	belongs to the thioredoxin family
AWV81_RS14595	COG3534	alpha-L-arabinofuranosidase
AWV81_RS14600	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AWV81_RS14605	COG2086	electron transfer activity
AWV81_RS14610	COG1024	Enoyl-CoA hydratase
AWV81_RS14615	COG1309	transcriptional regulator
AWV81_RS14620	COG0318	PFAM AMP-dependent synthetase and ligase
AWV81_RS14625	COG3766	membrane
AWV81_RS14630	COG1193	negative regulation of DNA recombination
AWV81_RS14635	COG1796	DNA polymerase
AWV81_RS14635	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AWV81_RS14640	COG1286	toxin biosynthetic process
AWV81_RS14645	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AWV81_RS14650	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWV81_RS14655	COG0072	phenylalanine-tRNA ligase activity
AWV81_RS14655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWV81_RS14660	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AWV81_RS14670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWV81_RS14680	COG3835	regulator
AWV81_RS14685	COG0277	FAD linked oxidase domain protein
AWV81_RS14690	COG0247	lactate metabolic process
AWV81_RS14695	COG0346	lactoylglutathione lyase activity
AWV81_RS14700	COG1966	Carbon starvation protein
AWV81_RS14705	COG3534	alpha-L-arabinofuranosidase
AWV81_RS14710	COG0395	ABC-type sugar transport system, permease component
AWV81_RS14715	COG1175	transmembrane transport
AWV81_RS14720	COG1653	transport
AWV81_RS14725	COG0371	Dehydrogenase
AWV81_RS14730	COG0647	UMP catabolic process
AWV81_RS14735	COG0235	Class ii aldolase
AWV81_RS14740	COG1069	ribulokinase activity
AWV81_RS14745	COG2160	L-arabinose isomerase activity
AWV81_RS14755	COG1363	Peptidase, m42
AWV81_RS14765	COG3326	Membrane
AWV81_RS14770	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AWV81_RS14775	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AWV81_RS14780	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AWV81_RS14790	COG1346	cytolysis
AWV81_RS14795	COG1380	Effector of murein hydrolase LrgA
AWV81_RS14800	COG3279	Response regulator of the LytR AlgR family
AWV81_RS14805	COG3275	phosphorelay sensor kinase activity
AWV81_RS14810	COG1011	Hydrolase
AWV81_RS14815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWV81_RS14825	COG0398	Pfam SNARE associated Golgi protein
AWV81_RS14830	COG1484	DNA-dependent DNA replication
AWV81_RS14835	COG3611	Membrane attachment protein
AWV81_RS14840	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWV81_RS14845	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AWV81_RS14850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWV81_RS14855	COG1733	regulation of RNA biosynthetic process
AWV81_RS14860	COG2814	Major facilitator Superfamily
AWV81_RS14865	COG0656	L-ascorbic acid biosynthetic process
AWV81_RS14870	COG0237	dephospho-CoA kinase activity
AWV81_RS14885	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AWV81_RS14890	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWV81_RS14890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWV81_RS14895	COG5002	protein histidine kinase activity
AWV81_RS14900	COG0745	RESPONSE REGULATOR receiver
AWV81_RS14905	COG0039	L-malate dehydrogenase activity
AWV81_RS14910	COG0538	isocitrate dehydrogenase activity
AWV81_RS14915	COG0372	Belongs to the citrate synthase family
AWV81_RS14920	COG2707	UPF0756 membrane protein
AWV81_RS14925	COG0628	permease
AWV81_RS14930	COG3030	protein affecting phage T7 exclusion by the F plasmid
AWV81_RS14935	COG0469	pyruvate kinase activity
AWV81_RS14940	COG0205	6-phosphofructokinase activity
AWV81_RS14945	COG0825	malonyl-CoA metabolic process
AWV81_RS14950	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AWV81_RS14955	COG0281	malic enzyme
AWV81_RS14960	COG0587	DNA-directed DNA polymerase activity
AWV81_RS14980	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AWV81_RS14990	COG4109	DRTGG domain
AWV81_RS15000	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AWV81_RS15005	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS15015	COG0165	Argininosuccinate lyase
AWV81_RS15020	COG0137	argininosuccinate synthase activity
AWV81_RS15025	COG0521	Mo-molybdopterin cofactor biosynthetic process
AWV81_RS15030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AWV81_RS15040	COG0827	DNA restriction-modification system
AWV81_RS15045	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AWV81_RS15050	COG3874	Sporulation protein YtfJ
AWV81_RS15060	COG1714	RDD family
AWV81_RS15065	COG0616	signal peptide processing
AWV81_RS15070	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWV81_RS15075	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AWV81_RS15080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWV81_RS15090	COG0301	tRNA thio-modification
AWV81_RS15095	COG1104	cysteine desulfurase activity
AWV81_RS15100	COG1114	Component of the transport system for branched-chain amino acids
AWV81_RS15105	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AWV81_RS15110	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AWV81_RS15115	COG1309	transcriptional regulator
AWV81_RS15120	COG1956	GAF domain-containing protein
AWV81_RS15125	COG2199	diguanylate cyclase activity
AWV81_RS15125	COG2203	Gaf domain
AWV81_RS15130	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWV81_RS15140	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWV81_RS15145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWV81_RS15150	COG0454	-acetyltransferase
AWV81_RS15155	COG0517	IMP dehydrogenase activity
AWV81_RS15160	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWV81_RS15165	COG1360	Flagellar Motor Protein
AWV81_RS15170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AWV81_RS15175	COG1609	Transcriptional regulator
AWV81_RS15180	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AWV81_RS15180	COG1605	Chorismate mutase
AWV81_RS15185	COG3118	belongs to the thioredoxin family
AWV81_RS15190	COG4980	gas vesicle protein
AWV81_RS15195	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AWV81_RS15200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AWV81_RS15205	COG1674	ftsk spoiiie
AWV81_RS15210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWV81_RS15215	COG4848	Belongs to the UPF0354 family
AWV81_RS15220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_RS15230	COG1363	Peptidase, m42
AWV81_RS15235	COG5584	Small secreted protein
AWV81_RS15240	COG0281	malic enzyme
AWV81_RS15245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWV81_RS15250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AWV81_RS15260	COG0510	thiamine kinase activity
AWV81_RS15265	COG1523	belongs to the glycosyl hydrolase 13 family
AWV81_RS15270	COG1597	lipid kinase activity
AWV81_RS15280	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AWV81_RS15285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWV81_RS15290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWV81_RS15295	COG2252	PERMEase
AWV81_RS15300	COG4473	ABC transporter
AWV81_RS15305	COG1131	(ABC) transporter
AWV81_RS15310	COG1349	DNA-binding transcription factor activity
AWV81_RS15315	COG1187	pseudouridine synthase activity
AWV81_RS15320	COG2244	polysaccharide biosynthetic process
AWV81_RS15325	COG2081	HI0933 family
AWV81_RS15330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AWV81_RS15340	COG5578	integral membrane protein
AWV81_RS15350	COG1653	transport
AWV81_RS15355	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AWV81_RS15360	COG4209	transmembrane transport
AWV81_RS15370	COG1653	transport
AWV81_RS15375	COG0395	ABC-type sugar transport system, permease component
AWV81_RS15380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWV81_RS15385	COG2124	cytochrome p450
AWV81_RS15405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AWV81_RS15410	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
AWV81_RS15415	COG1073	alpha beta
AWV81_RS15420	COG1609	Transcriptional regulator
AWV81_RS15425	COG1653	transport
AWV81_RS15430	COG1175	transmembrane transport
AWV81_RS15435	COG0395	ABC-type sugar transport system, permease component
AWV81_RS15440	COG1486	melibiose metabolic process
AWV81_RS15445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWV81_RS15450	COG0495	leucyl-tRNA aminoacylation
AWV81_RS15460	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_RS15460	COG2202	Pas domain
AWV81_RS15465	COG2814	Major facilitator Superfamily
AWV81_RS15470	COG2433	Pfam Transposase IS66
AWV81_RS15475	COG0577	efflux transmembrane transporter activity
AWV81_RS15480	COG1136	(ABC) transporter
AWV81_RS15485	COG2205	protein histidine kinase activity
AWV81_RS15490	COG0745	RESPONSE REGULATOR receiver
AWV81_RS15495	COG0577	efflux transmembrane transporter activity
AWV81_RS15500	COG1136	(ABC) transporter
AWV81_RS15515	COG1131	(ABC) transporter
AWV81_RS15520	COG1725	Transcriptional regulator
AWV81_RS15535	COG1242	4 iron, 4 sulfur cluster binding
AWV81_RS15540	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AWV81_RS15550	COG2267	carboxylic ester hydrolase activity
AWV81_RS15555	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AWV81_RS15560	COG1113	amino acid transport
AWV81_RS15565	COG0367	asparagine synthase
AWV81_RS15570	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AWV81_RS15575	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AWV81_RS15585	COG1506	peptidase
AWV81_RS15590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWV81_RS15595	COG1116	anion transmembrane transporter activity
AWV81_RS15600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWV81_RS15605	COG0494	nUDIX hydrolase
AWV81_RS15610	COG4824	toxin secretion phage lysis holin
AWV81_RS15615	COG0783	Belongs to the Dps family
AWV81_RS15630	COG1854	S-ribosylhomocysteine lyase activity
AWV81_RS15635	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AWV81_RS15640	COG0288	reversible hydration of carbon dioxide
AWV81_RS15645	COG0254	rRNA binding
AWV81_RS15650	COG1271	oxidase subunit
AWV81_RS15655	COG1294	oxidase, subunit
AWV81_RS15665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWV81_RS15670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWV81_RS15670	COG1321	iron dependent repressor
AWV81_RS15675	COG1121	(ABC) transporter
AWV81_RS15680	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWV81_RS15685	COG4948	Mandelate Racemase Muconate Lactonizing
AWV81_RS15690	COG0318	PFAM AMP-dependent synthetase and ligase
AWV81_RS15695	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AWV81_RS15700	COG0596	Alpha beta hydrolase
AWV81_RS15705	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AWV81_RS15710	COG1169	isochorismate synthase
AWV81_RS15715	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AWV81_RS15720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AWV81_RS15725	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AWV81_RS15730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWV81_RS15735	COG0438	transferase activity, transferring glycosyl groups
AWV81_RS15745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWV81_RS15750	COG0438	transferase activity, transferring glycosyl groups
AWV81_RS15755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWV81_RS15760	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AWV81_RS15765	COG0058	SHG alpha-glucan phosphorylase activity
AWV81_RS15770	COG0297	glycogen (starch) synthase activity
AWV81_RS15775	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWV81_RS15780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWV81_RS15785	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AWV81_RS15915	COG3859	Proton-coupled thiamine transporter YuaJ
AWV81_RS15920	COG1247	-acetyltransferase
AWV81_RS15925	COG2268	Band 7 protein
AWV81_RS15930	COG1585	Membrane protein implicated in regulation of membrane protease activity
AWV81_RS15935	COG2318	DinB family
AWV81_RS15945	COG1454	alcohol dehydrogenase
AWV81_RS15950	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_RS15955	COG1510	regulation of RNA biosynthetic process
AWV81_RS15965	COG0569	domain protein
AWV81_RS15970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWV81_RS15975	COG4682	membrane
AWV81_RS15980	COG1705	Flagellar rod assembly protein muramidase FlgJ
AWV81_RS15985	COG0477	Major facilitator Superfamily
AWV81_RS15990	COG5553	Cysteine dioxygenase type I
AWV81_RS16000	COG1968	undecaprenyl-diphosphatase activity
AWV81_RS16005	COG0628	permease
AWV81_RS16010	COG0673	inositol 2-dehydrogenase activity
AWV81_RS16015	COG4806	L-rhamnose isomerase
AWV81_RS16020	COG3254	rhamnose metabolic process
AWV81_RS16025	COG1070	Carbohydrate kinase
AWV81_RS16030	COG1349	DNA-binding transcription factor activity
AWV81_RS16035	COG3347	Dehydrogenase
AWV81_RS16035	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS16050	COG0840	transmembrane signaling receptor activity
AWV81_RS16060	COG0840	transmembrane signaling receptor activity
AWV81_RS16075	COG0432	Pfam Uncharacterised protein family UPF0047
AWV81_RS16080	COG0366	Alpha amylase catalytic
AWV81_RS16085	COG1253	flavin adenine dinucleotide binding
AWV81_RS16090	COG2738	Putative neutral zinc metallopeptidase
AWV81_RS16105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AWV81_RS16120	COG0166	Belongs to the GPI family
AWV81_RS16125	COG1979	alcohol dehydrogenase
AWV81_RS16130	COG1979	alcohol dehydrogenase
AWV81_RS16135	COG2155	Conserved Protein
AWV81_RS16140	COG1098	S1 RNA binding domain
AWV81_RS16145	COG0436	Aminotransferase
AWV81_RS16150	COG1522	sequence-specific DNA binding
AWV81_RS16155	COG2267	carboxylic ester hydrolase activity
AWV81_RS16165	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AWV81_RS16170	COG2205	protein histidine kinase activity
AWV81_RS16180	COG5018	Exonuclease
AWV81_RS16190	COG2814	Major facilitator Superfamily
AWV81_RS16195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWV81_RS16200	COG3011	Protein conserved in bacteria
AWV81_RS16210	COG3290	protein histidine kinase activity
AWV81_RS16215	COG4565	transcriptional regulatory protein
AWV81_RS16220	COG1744	ABC transporter substrate-binding protein PnrA-like
AWV81_RS16225	COG3845	ABC transporter
AWV81_RS16230	COG4603	Belongs to the binding-protein-dependent transport system permease family
AWV81_RS16235	COG1079	Belongs to the binding-protein-dependent transport system permease family
AWV81_RS16240	COG3493	citrate carrier protein
AWV81_RS16250	COG2111	Na H antiporter
AWV81_RS16250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWV81_RS16255	COG2111	Na H antiporter
AWV81_RS16260	COG1006	Multisubunit Na H antiporter MnhC subunit
AWV81_RS16265	COG0651	ATP synthesis coupled electron transport
AWV81_RS16270	COG1863	multisubunit Na H antiporter MnhE subunit
AWV81_RS16275	COG2212	antiporter activity
AWV81_RS16280	COG1320	monovalent cation:proton antiporter activity
AWV81_RS16285	COG2050	protein possibly involved in aromatic compounds catabolism
AWV81_RS16290	COG2197	response regulator
AWV81_RS16295	COG4585	Histidine kinase
AWV81_RS16305	COG0142	geranyltranstransferase activity
AWV81_RS16320	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AWV81_RS16325	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AWV81_RS16330	COG1335	isochorismatase
AWV81_RS16335	COG5506	Protein of unknown function (DUF1694)
AWV81_RS16350	COG0628	permease
AWV81_RS16365	COG1418	mRNA catabolic process
AWV81_RS16370	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS16380	COG1511	domain protein
AWV81_RS16385	COG1674	ftsk spoiiie
AWV81_RS16385	COG0433	COG0433 Predicted ATPase
AWV81_RS16390	COG4499	WXG100 protein secretion system (Wss), protein YukC
AWV81_RS16395	COG5417	Belongs to the EsaB family
AWV81_RS16400	COG4842	Belongs to the WXG100 family
AWV81_RS16405	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AWV81_RS16405	COG2508	Transcriptional regulator
AWV81_RS16410	COG0686	Belongs to the AlaDH PNT family
AWV81_RS16415	COG5634	Uncharacterized conserved protein (DUF2278)
AWV81_RS16420	COG3251	PFAM MbtH domain protein
AWV81_RS16425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWV81_RS16430	COG1535	isochorismatase
AWV81_RS16430	COG3433	isochorismatase activity
AWV81_RS16435	COG1021	2,3-dihydroxybenzoate-AMP ligase
AWV81_RS16440	COG1169	isochorismate synthase
AWV81_RS16445	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS16450	COG2819	hydrolase of the alpha beta superfamily
AWV81_RS16455	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AWV81_RS16460	COG1268	BioY protein
AWV81_RS16465	COG2056	Na+-H+ antiporter family
AWV81_RS16470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AWV81_RS16475	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AWV81_RS16480	COG3584	3D domain protein
AWV81_RS16495	COG1252	NADH dehydrogenase
AWV81_RS16500	COG0492	ferredoxin-NADP+ reductase activity
AWV81_RS16510	COG0516	GMP reductase activity
AWV81_RS16515	COG2808	Putative FMN-binding domain
AWV81_RS16520	COG0456	acetyltransferase
AWV81_RS16615	COG0582	viral genome integration into host DNA
AWV81_RS16625	COG4974	Belongs to the 'phage' integrase family
AWV81_RS16630	COG0316	Belongs to the HesB IscA family
AWV81_RS16635	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AWV81_RS16640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWV81_RS16645	COG4844	belongs to the
AWV81_RS16650	COG1252	NADH dehydrogenase
AWV81_RS16655	COG4837	Protein of unknown function (DUF1462)
AWV81_RS16660	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AWV81_RS16665	COG4946	Tricorn protease homolog
AWV81_RS16665	COG0823	Involved in the tonB-independent uptake of proteins
AWV81_RS16665	COG1506	peptidase
AWV81_RS16670	COG0083	homoserine kinase activity
AWV81_RS16675	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AWV81_RS16680	COG0460	homoserine dehydrogenase
AWV81_RS16685	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWV81_RS16690	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AWV81_RS16695	COG0647	UMP catabolic process
AWV81_RS16700	COG2445	Protein of unknown function DUF86
AWV81_RS16705	COG4470	Protein conserved in bacteria
AWV81_RS16715	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWV81_RS16720	COG0739	heme binding
AWV81_RS16730	COG3377	Domain of unknown function (DUF1805)
AWV81_RS16735	COG0737	Belongs to the 5'-nucleotidase family
AWV81_RS16740	COG0730	response to heat
AWV81_RS16745	COG1801	Protein of unknown function DUF72
AWV81_RS16755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWV81_RS16760	COG2508	Transcriptional regulator
AWV81_RS16765	COG2233	PERMEase
AWV81_RS16770	COG2233	PERMEase
AWV81_RS16775	COG3648	Uricase
AWV81_RS16775	COG3195	allantoin biosynthetic process
AWV81_RS16780	COG2351	hydroxyisourate hydrolase activity
AWV81_RS16790	COG2080	2 iron, 2 sulfur cluster binding
AWV81_RS16795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AWV81_RS16800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AWV81_RS16805	COG2068	MobA-Related Protein
AWV81_RS16810	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AWV81_RS16815	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AWV81_RS16820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWV81_RS16830	COG2356	endonuclease I
AWV81_RS16835	COG3842	ATPase activity
AWV81_RS16840	COG2188	Transcriptional regulator
AWV81_RS16845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWV81_RS16855	COG1175	transmembrane transport
AWV81_RS16860	COG1653	transport
AWV81_RS16865	COG2222	sugar isomerase
AWV81_RS16870	COG0322	excinuclease ABC activity
AWV81_RS16875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWV81_RS16890	COG0346	lactoylglutathione lyase activity
AWV81_RS16895	COG0640	Transcriptional regulator
AWV81_RS16900	COG0719	Fe-S assembly protein
AWV81_RS16905	COG0822	iron-sulfur transferase activity
AWV81_RS16910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWV81_RS16915	COG0719	Fe-S assembly protein
AWV81_RS16920	COG0396	ATPase activity
AWV81_RS16935	COG1464	Belongs to the NlpA lipoprotein family
AWV81_RS16940	COG2011	ABC-type metal ion transport system permease component
AWV81_RS16945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWV81_RS16955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_RS16960	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AWV81_RS16970	COG0509	glycine decarboxylation via glycine cleavage system
AWV81_RS16975	COG1393	Belongs to the ArsC family
AWV81_RS16980	COG1960	acyl-CoA dehydrogenase activity
AWV81_RS16985	COG0183	Belongs to the thiolase family
AWV81_RS16990	COG1024	Enoyl-CoA hydratase
AWV81_RS16990	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWV81_RS17010	COG5577	PFAM Coat F domain
AWV81_RS17015	COG1846	Transcriptional regulator
AWV81_RS17020	COG0477	Major facilitator Superfamily
AWV81_RS17025	COG1942	4-Oxalocrotonate Tautomerase
AWV81_RS17030	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS17035	COG0583	DNA-binding transcription factor activity
AWV81_RS17045	COG1120	ATPase activity
AWV81_RS17065	COG1131	(ABC) transporter
AWV81_RS17115	COG0783	Belongs to the Dps family
AWV81_RS17120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWV81_RS17125	COG0745	RESPONSE REGULATOR receiver
AWV81_RS17130	COG2205	protein histidine kinase activity
AWV81_RS17130	COG2770	Histidine kinase
AWV81_RS17140	COG1309	transcriptional regulator
AWV81_RS17145	COG0114	fumarate hydratase activity
AWV81_RS17155	COG0697	spore germination
AWV81_RS17160	COG0814	amino acid
AWV81_RS17170	COG2197	response regulator
AWV81_RS17175	COG4585	Histidine kinase
AWV81_RS17180	COG4758	membrane
AWV81_RS17185	COG3595	metallopeptidase activity
AWV81_RS17190	COG1842	Phage shock protein A
AWV81_RS17195	COG4758	membrane
AWV81_RS17200	COG2814	Major facilitator Superfamily
AWV81_RS17205	COG2096	Adenosyltransferase
AWV81_RS17210	COG1120	ATPase activity
AWV81_RS17215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_RS17220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWV81_RS17225	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS17230	COG3386	PFAM SMP-30 Gluconolaconase
AWV81_RS17235	COG2205	protein histidine kinase activity
AWV81_RS17240	COG0745	RESPONSE REGULATOR receiver
AWV81_RS17250	COG1191	sigma factor activity
AWV81_RS17260	COG2140	Oxalate decarboxylase
AWV81_RS17270	COG0577	efflux transmembrane transporter activity
AWV81_RS17275	COG1136	(ABC) transporter
AWV81_RS17280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWV81_RS17285	COG1120	ATPase activity
AWV81_RS17290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_RS17295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_RS17300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWV81_RS17310	COG0531	amino acid
AWV81_RS17320	COG1988	membrane-bound metal-dependent
AWV81_RS17325	COG1368	sulfuric ester hydrolase activity
AWV81_RS17330	COG1910	domain protein
AWV81_RS17335	COG0725	ABC transporter, periplasmic molybdate-binding protein
AWV81_RS17340	COG4149	molybdate abc transporter
AWV81_RS17345	COG0656	L-ascorbic acid biosynthetic process
AWV81_RS17355	COG0025	NhaP-type Na H and K H
AWV81_RS17360	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWV81_RS17365	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWV81_RS17370	COG3973	AAA domain
AWV81_RS17380	COG2860	membrane
AWV81_RS17385	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AWV81_RS17390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AWV81_RS17395	COG2217	Heavy metal translocating P-type atpase
AWV81_RS17400	COG2217	Heavy metal translocating P-type atpase
AWV81_RS17405	COG2608	mercury ion transmembrane transporter activity
AWV81_RS17410	COG1937	Protein conserved in bacteria
AWV81_RS17415	COG0673	inositol 2-dehydrogenase activity
AWV81_RS17425	COG1289	transmembrane transporter activity
AWV81_RS17435	COG2076	Multidrug Resistance protein
AWV81_RS17440	COG1309	transcriptional regulator
AWV81_RS17445	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS17455	COG5444	nuclease activity
AWV81_RS17470	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_RS17470	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWV81_RS17475	COG4824	toxin secretion phage lysis holin
AWV81_RS17495	COG3942	CHAP domain
AWV81_RS17495	COG1705	Flagellar rod assembly protein muramidase FlgJ
AWV81_RS17715	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AWV81_RS17720	COG0557	exoribonuclease II activity
AWV81_RS17725	COG1647	Serine aminopeptidase, S33
AWV81_RS17730	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWV81_RS17735	COG0596	Alpha beta hydrolase
AWV81_RS17740	COG1476	TRANSCRIPTIONal
AWV81_RS17745	COG1396	sequence-specific DNA binding
AWV81_RS17750	COG1396	sequence-specific DNA binding
AWV81_RS17755	COG1733	regulation of RNA biosynthetic process
AWV81_RS17760	COG0840	transmembrane signaling receptor activity
AWV81_RS17765	COG1174	glycine betaine transport
AWV81_RS17770	COG1732	Glycine betaine
AWV81_RS17775	COG1174	glycine betaine transport
AWV81_RS17780	COG0517	IMP dehydrogenase activity
AWV81_RS17780	COG1125	glycine betaine transport
AWV81_RS17785	COG1510	regulation of RNA biosynthetic process
AWV81_RS17790	COG1174	glycine betaine transport
AWV81_RS17795	COG1732	Glycine betaine
AWV81_RS17800	COG1174	glycine betaine transport
AWV81_RS17805	COG1125	glycine betaine transport
AWV81_RS17805	COG0517	IMP dehydrogenase activity
AWV81_RS17810	COG1510	regulation of RNA biosynthetic process
AWV81_RS17815	COG2095	MarC family integral membrane protein
AWV81_RS17825	COG3064	Membrane
AWV81_RS17830	COG4640	response to antibiotic
AWV81_RS17835	COG0456	acetyltransferase
AWV81_RS17840	COG0148	phosphopyruvate hydratase activity
AWV81_RS17845	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AWV81_RS17850	COG0149	triose-phosphate isomerase activity
AWV81_RS17855	COG0126	phosphoglycerate kinase activity
AWV81_RS17865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWV81_RS17870	COG2390	Transcriptional regulator
AWV81_RS17875	COG2814	Major facilitator Superfamily
AWV81_RS17880	COG1609	Transcriptional regulator
AWV81_RS17885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWV81_RS17890	COG0583	DNA-binding transcription factor activity
AWV81_RS17895	COG0697	spore germination
AWV81_RS17900	COG1113	amino acid transport
AWV81_RS17910	COG1556	Lactate utilization protein
AWV81_RS17915	COG1139	Iron-sulfur cluster binding protein
AWV81_RS17920	COG0247	lactate metabolic process
AWV81_RS17925	COG2197	response regulator
AWV81_RS17930	COG4585	Histidine kinase
AWV81_RS17935	COG0842	Transport permease protein
AWV81_RS17940	COG1131	(ABC) transporter
AWV81_RS17960	COG0596	Alpha beta hydrolase
AWV81_RS17965	COG2208	phosphoserine phosphatase activity
AWV81_RS17970	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AWV81_RS17975	COG1874	Beta-galactosidase
AWV81_RS17980	COG3833	ABC-type maltose transport systems, permease component
AWV81_RS17985	COG1175	transmembrane transport
AWV81_RS17990	COG2182	Extracellular solute-binding protein
AWV81_RS17995	COG1609	Transcriptional regulator
AWV81_RS18000	COG2186	Transcriptional regulator
AWV81_RS18005	COG1620	l-lactate permease
AWV81_RS18010	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AWV81_RS18020	COG5039	Polysaccharide pyruvyl transferase
AWV81_RS18025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AWV81_RS18030	COG0110	maltose O-acetyltransferase activity
AWV81_RS18035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AWV81_RS18040	COG2244	polysaccharide biosynthetic process
AWV81_RS18045	COG1216	Glycosyl transferase, family 2
AWV81_RS18050	COG5039	Polysaccharide pyruvyl transferase
AWV81_RS18055	COG1216	Glycosyl transferase, family 2
AWV81_RS18065	COG0438	transferase activity, transferring glycosyl groups
AWV81_RS18070	COG1215	transferase activity, transferring glycosyl groups
AWV81_RS18075	COG0438	transferase activity, transferring glycosyl groups
AWV81_RS18080	COG1086	Polysaccharide biosynthesis protein
AWV81_RS18085	COG0489	protein tyrosine kinase activity
AWV81_RS18090	COG3944	biosynthesis protein
AWV81_RS18095	COG1396	sequence-specific DNA binding
AWV81_RS18100	COG2272	Belongs to the type-B carboxylesterase lipase family
AWV81_RS18110	COG3479	Phenolic acid decarboxylase
AWV81_RS18120	COG1794	racemase activity, acting on amino acids and derivatives
AWV81_RS18130	COG1621	beta-fructofuranosidase activity
AWV81_RS18135	COG1621	beta-fructofuranosidase activity
AWV81_RS18140	COG0531	amino acid
AWV81_RS18145	COG1309	transcriptional regulator
AWV81_RS18150	COG2076	Multidrug Resistance protein
AWV81_RS18155	COG2076	Multidrug Resistance protein
AWV81_RS18175	COG1674	ftsk spoiiie
AWV81_RS18195	COG1388	LysM domain
AWV81_RS18195	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_RS18195	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWV81_RS18230	COG1705	Flagellar rod assembly protein muramidase FlgJ
AWV81_RS18310	COG0582	viral genome integration into host DNA
AWV81_RS18410	COG4974	Belongs to the 'phage' integrase family
AWV81_RS18420	COG0740	serine-type endopeptidase activity
AWV81_RS18425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWV81_RS18430	COG0366	Alpha amylase catalytic
AWV81_RS18435	COG1554	hydrolase, family 65, central catalytic
AWV81_RS18440	COG5521	maltodextrose utilization protein MalA
AWV81_RS18445	COG3833	ABC-type maltose transport systems, permease component
AWV81_RS18450	COG1175	transmembrane transport
AWV81_RS18455	COG2182	Extracellular solute-binding protein
AWV81_RS18465	COG1609	Transcriptional regulator
AWV81_RS18470	COG1611	Belongs to the LOG family
AWV81_RS18480	COG0659	secondary active sulfate transmembrane transporter activity
AWV81_RS18485	COG0288	reversible hydration of carbon dioxide
AWV81_RS18490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWV81_RS18495	COG0577	efflux transmembrane transporter activity
AWV81_RS18500	COG1136	(ABC) transporter
AWV81_RS18505	COG5002	protein histidine kinase activity
AWV81_RS18510	COG0745	RESPONSE REGULATOR receiver
AWV81_RS18520	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AWV81_RS18525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_RS18530	COG1481	regulation of sporulation
AWV81_RS18535	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AWV81_RS18540	COG1660	Displays ATPase and GTPase activities
AWV81_RS18545	COG1051	belongs to the nudix hydrolase family
AWV81_RS18550	COG0492	ferredoxin-NADP+ reductase activity
AWV81_RS18555	COG3883	PFAM NLP P60 protein
AWV81_RS18555	COG0791	NLP P60 protein
AWV81_RS18560	COG0457	Tetratricopeptide repeat
AWV81_RS18565	COG1132	(ABC) transporter
AWV81_RS18585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AWV81_RS18585	COG0140	phosphoribosyl-ATP diphosphatase activity
AWV81_RS18590	COG0107	imidazoleglycerol-phosphate synthase activity
AWV81_RS18595	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AWV81_RS18600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AWV81_RS18605	COG0131	Imidazoleglycerol-phosphate dehydratase
AWV81_RS18610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AWV81_RS18615	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AWV81_RS18620	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AWV81_RS18625	COG4990	cell redox homeostasis
AWV81_RS18630	COG5297	Belongs to the glycosyl hydrolase family 6
AWV81_RS18640	COG2801	Transposase and inactivated derivatives
AWV81_RS18650	COG0546	phosphoglycolate phosphatase activity
AWV81_RS18655	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AWV81_RS18660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AWV81_RS18665	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AWV81_RS18670	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AWV81_RS18675	COG0363	glucosamine-6-phosphate deaminase activity
AWV81_RS18680	COG2188	Transcriptional regulator
AWV81_RS18685	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AWV81_RS18700	COG1950	PFAM Membrane protein of
AWV81_RS18705	COG1983	PspC domain protein
AWV81_RS18710	COG3595	metallopeptidase activity
AWV81_RS18725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AWV81_RS18730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AWV81_RS18735	COG0556	nucleotide-excision repair
AWV81_RS18740	COG4897	Protein conserved in bacteria
AWV81_RS18745	COG3848	Pyruvate phosphate dikinase
AWV81_RS18745	COG0574	Belongs to the PEP-utilizing enzyme family
AWV81_RS18750	COG1309	transcriptional regulator
AWV81_RS18755	COG2814	Major facilitator Superfamily
AWV81_RS18760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWV81_RS18770	COG0793	Belongs to the peptidase S41A family
AWV81_RS18770	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_RS18775	COG2177	Part of the ABC transporter FtsEX involved in
AWV81_RS18780	COG2884	Cell division ATP-binding protein ftsE
AWV81_RS18785	COG2010	Cytochrome c
AWV81_RS18790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWV81_RS18795	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AWV81_RS18800	COG0653	protein targeting
AWV81_RS18805	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AWV81_RS18820	COG1516	flagellar protein fliS
AWV81_RS18825	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AWV81_RS18830	COG1334	flagellar protein FlaG
AWV81_RS18835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AWV81_RS18840	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AWV81_RS18845	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AWV81_RS18855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AWV81_RS18860	COG4786	Flagellar basal body rod
AWV81_RS18860	COG1256	bacterial-type flagellum assembly
AWV81_RS18865	COG3418	PFAM FlgN family protein
AWV81_RS18870	COG2747	anti-sigma28 factor FlgM
AWV81_RS18880	COG1040	competence protein
AWV81_RS18890	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AWV81_RS18895	COG1307	EDD domain protein, DegV family
AWV81_RS18900	COG2197	response regulator
AWV81_RS18905	COG4585	Histidine kinase
AWV81_RS18910	COG1739	Uncharacterized protein family UPF0029
AWV81_RS18915	COG1316	TRANSCRIPTIONal
AWV81_RS18950	COG1131	(ABC) transporter
AWV81_RS18960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWV81_RS18965	COG0438	transferase activity, transferring glycosyl groups
AWV81_RS18970	COG1215	transferase activity, transferring glycosyl groups
AWV81_RS18975	COG3206	protein involved in exopolysaccharide biosynthesis
AWV81_RS18980	COG3307	-O-antigen
AWV81_RS18985	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AWV81_RS18990	COG0438	transferase activity, transferring glycosyl groups
AWV81_RS18990	COG0297	glycogen (starch) synthase activity
AWV81_RS18995	COG2244	polysaccharide biosynthetic process
AWV81_RS19010	COG2247	cell wall binding repeat
AWV81_RS19010	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWV81_RS19015	COG2385	sporulation resulting in formation of a cellular spore
AWV81_RS19015	COG2247	cell wall binding repeat
AWV81_RS19045	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AWV81_RS19050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AWV81_RS19060	COG1134	teichoic acid transport
AWV81_RS19065	COG1682	transport, permease protein
AWV81_RS19080	COG0463	Glycosyl transferase, family 2
AWV81_RS19080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWV81_RS19085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWV81_RS19090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AWV81_RS19095	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AWV81_RS19100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWV81_RS19105	COG4193	domain, Protein
AWV81_RS19110	COG1482	cell wall glycoprotein biosynthetic process
AWV81_RS19120	COG0697	spore germination
AWV81_RS19125	COG0814	amino acid
AWV81_RS19140	COG1316	TRANSCRIPTIONal
AWV81_RS19145	COG0561	phosphatase activity
AWV81_RS19150	COG0791	NLP P60 protein
AWV81_RS19160	COG2843	Capsule synthesis protein
AWV81_RS19170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AWV81_RS19175	COG1609	Transcriptional regulator
AWV81_RS19180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWV81_RS19185	COG1869	D-ribose catabolic process
AWV81_RS19190	COG1129	ABC transporter
AWV81_RS19195	COG1172	Belongs to the binding-protein-dependent transport system permease family
AWV81_RS19200	COG1879	ABC-type sugar transport system periplasmic component
AWV81_RS19205	COG3103	Sh3 type 3 domain protein
AWV81_RS19215	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWV81_RS19220	COG3527	Alpha-acetolactate decarboxylase
AWV81_RS19225	COG0028	Belongs to the TPP enzyme family
AWV81_RS19230	COG0583	DNA-binding transcription factor activity
AWV81_RS19235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AWV81_RS19250	COG5337	Spore coat protein CotH
AWV81_RS19260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWV81_RS19270	COG0405	Gamma-glutamyltransferase
AWV81_RS19275	COG1522	sequence-specific DNA binding
AWV81_RS19280	COG2059	Chromate
AWV81_RS19285	COG2059	Chromate
AWV81_RS19295	COG0655	NAD(P)H dehydrogenase (quinone) activity
AWV81_RS19300	COG0583	DNA-binding transcription factor activity
AWV81_RS19330	COG5444	nuclease activity
AWV81_RS19350	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AWV81_RS19355	COG4464	protein tyrosine phosphatase activity
AWV81_RS19360	COG0489	protein tyrosine kinase activity
AWV81_RS19365	COG3944	biosynthesis protein
AWV81_RS19375	COG4715	Zinc finger, swim domain protein
AWV81_RS19380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWV81_RS19385	COG0561	phosphatase activity
AWV81_RS19390	COG1349	DNA-binding transcription factor activity
AWV81_RS19395	COG0629	single-stranded DNA binding
AWV81_RS19410	COG3764	Sortase (surface protein transpeptidase)
AWV81_RS19415	COG2972	Histidine kinase
AWV81_RS19415	COG0745	RESPONSE REGULATOR receiver
AWV81_RS19420	COG1970	mechanosensitive ion channel activity
AWV81_RS19425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWV81_RS19430	COG0457	Tetratricopeptide repeat
AWV81_RS19435	COG4786	Flagellar basal body rod
AWV81_RS19440	COG4786	Flagellar basal body rod
AWV81_RS19445	COG1077	Cell shape determining protein MreB Mrl
AWV81_RS19450	COG1609	Transcriptional regulator
AWV81_RS19455	COG1846	Transcriptional regulator
AWV81_RS19460	COG2814	Major facilitator Superfamily
AWV81_RS19465	COG3420	alginic acid biosynthetic process
AWV81_RS19470	COG1953	Uracil, thiamine, allantoin
AWV81_RS19475	COG0477	Major facilitator Superfamily
AWV81_RS19480	COG1335	isochorismatase
AWV81_RS19490	COG0004	ammonium transporteR
AWV81_RS19495	COG0347	Belongs to the P(II) protein family
AWV81_RS19500	COG0671	phosphoesterase, PA-phosphatase related
AWV81_RS19510	COG0739	heme binding
AWV81_RS19515	COG1247	-acetyltransferase
AWV81_RS19525	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AWV81_RS19535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWV81_RS19540	COG0789	Transcriptional regulator
AWV81_RS19550	COG2910	NAD(P)H-binding
AWV81_RS19555	COG1959	2 iron, 2 sulfur cluster binding
AWV81_RS19560	COG0804	urea catabolic process
AWV81_RS19565	COG0832	Belongs to the urease beta subunit family
AWV81_RS19570	COG0831	urea catabolic process
AWV81_RS19580	COG3237	CsbD-like
AWV81_RS19585	COG1994	Peptidase M50
AWV81_RS19590	COG0457	Tetratricopeptide repeat
AWV81_RS19595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AWV81_RS19600	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AWV81_RS19610	COG2304	oxidoreductase activity
AWV81_RS19620	COG2304	oxidoreductase activity
AWV81_RS19625	COG2385	sporulation resulting in formation of a cellular spore
AWV81_RS19630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWV81_RS19640	COG4836	Membrane
AWV81_RS19650	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AWV81_RS19655	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AWV81_RS19660	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AWV81_RS19665	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AWV81_RS19670	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWV81_RS19675	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWV81_RS19690	COG0356	it plays a direct role in the translocation of protons across the membrane
AWV81_RS19700	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AWV81_RS19705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AWV81_RS19710	COG4475	Protein of unknown function (DUF436)
AWV81_RS19715	COG0698	ribose 5-phosphate isomerase
AWV81_RS19720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWV81_RS19725	COG1971	Probably functions as a manganese efflux pump
AWV81_RS19730	COG0009	L-threonylcarbamoyladenylate synthase
AWV81_RS19735	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AWV81_RS19755	COG2890	protein-(glutamine-N5) methyltransferase activity
AWV81_RS19760	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AWV81_RS19765	COG0346	lactoylglutathione lyase activity
AWV81_RS19770	COG0789	Transcriptional regulator
AWV81_RS19775	COG0679	Auxin Efflux Carrier
AWV81_RS19780	COG0281	malic enzyme
AWV81_RS19785	COG1435	thymidine kinase activity
AWV81_RS19795	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AWV81_RS19805	COG1494	fructose-1,6-bisphosphatase
AWV81_RS19810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWV81_RS19815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWV81_RS19820	COG0191	fructose-bisphosphate aldolase activity
AWV81_RS19825	COG2204	response regulator
AWV81_RS19830	COG4821	SIS domain
AWV81_RS19835	COG0504	CTP synthase activity
AWV81_RS19840	COG3343	RNA polymerase activity
AWV81_RS19845	COG1960	acyl-CoA dehydrogenase activity
AWV81_RS19850	COG0247	lactate metabolic process
AWV81_RS19850	COG2181	nitrate reductase activity
AWV81_RS19855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWV81_RS19860	COG4294	response to UV
AWV81_RS19870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AWV81_RS19880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWV81_RS19885	COG2181	nitrate reductase activity
AWV81_RS19890	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AWV81_RS19895	COG1140	nitrate reductase beta subunit
AWV81_RS19900	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AWV81_RS19905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWV81_RS19915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWV81_RS19920	COG2223	nitrite transmembrane transporter activity
AWV81_RS19925	COG0018	arginyl-trna synthetase
AWV81_RS19930	COG4506	Protein conserved in bacteria
AWV81_RS19940	COG0535	radical SAM domain protein
AWV81_RS19950	COG1131	(ABC) transporter
AWV81_RS19955	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWV81_RS19960	COG0612	Peptidase, M16
AWV81_RS19965	COG0612	Peptidase, M16
AWV81_RS19975	COG3391	amine dehydrogenase activity
AWV81_RS19980	COG3391	amine dehydrogenase activity
AWV81_RS19990	COG0457	Tetratricopeptide repeat
AWV81_RS20000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AWV81_RS20005	COG0010	Belongs to the arginase family
AWV81_RS20010	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AWV81_RS20015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWV81_RS20030	COG1994	Peptidase M50
AWV81_RS20035	COG1942	4-Oxalocrotonate Tautomerase
AWV81_RS20040	COG1846	Transcriptional regulator
AWV81_RS20045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWV81_RS20055	COG0477	Major facilitator Superfamily
AWV81_RS20060	COG1959	2 iron, 2 sulfur cluster binding
AWV81_RS20065	COG3465	dGTPase activity
AWV81_RS20070	COG1078	dGTPase activity
AWV81_RS20075	COG4844	belongs to the
AWV81_RS20085	COG0697	spore germination
AWV81_RS20090	COG0095	Lipoate-protein ligase
AWV81_RS20095	COG0583	DNA-binding transcription factor activity
AWV81_RS20100	COG0280	phosphate acetyltransferase
AWV81_RS20105	COG3253	May function as heme-dependent peroxidase
AWV81_RS20110	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS20115	COG0436	Aminotransferase
AWV81_RS20120	COG2814	Major facilitator Superfamily
AWV81_RS20125	COG0151	Belongs to the GarS family
AWV81_RS20130	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS20135	COG1917	Cupin 2, conserved barrel domain protein
AWV81_RS20140	COG0077	Prephenate dehydratase
AWV81_RS20145	COG2814	Major facilitator Superfamily
AWV81_RS20150	COG0833	amino acid
AWV81_RS20155	COG4187	Peptidase family M20/M25/M40
AWV81_RS20160	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_RS20165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWV81_RS20175	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AWV81_RS20180	COG1091	dTDP-4-dehydrorhamnose reductase activity
AWV81_RS20185	COG1088	dTDP-glucose 4,6-dehydratase activity
AWV81_RS20190	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AWV81_RS20195	COG3980	spore coat polysaccharide biosynthesis protein
AWV81_RS20200	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AWV81_RS20205	COG2089	acid synthase
AWV81_RS20210	COG0456	acetyltransferase
AWV81_RS20215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AWV81_RS20220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWV81_RS20225	COG0463	Glycosyl transferase, family 2
AWV81_RS20240	COG2363	Small membrane protein
AWV81_RS20245	COG2233	PERMEase
AWV81_RS20255	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_RS20260	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AWV81_RS20265	COG1216	Glycosyl transferase, family 2
AWV81_RS20270	COG0351	phosphomethylpyrimidine kinase
AWV81_RS20280	COG1621	beta-fructofuranosidase activity
AWV81_RS20285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_RS20285	COG1263	PTS System
AWV81_RS20290	COG2116	formate transmembrane transporter activity
AWV81_RS20305	COG1404	Belongs to the peptidase S8 family
AWV81_RS20310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWV81_RS20315	COG0778	Nitroreductase
AWV81_RS20320	COG0772	Belongs to the SEDS family
AWV81_RS20335	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AWV81_RS20340	COG1845	cytochrome c oxidase, subunit III
AWV81_RS20345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWV81_RS20350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWV81_RS20355	COG2261	transglycosylase associated protein
AWV81_RS20360	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AWV81_RS20365	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AWV81_RS20370	COG2246	polysaccharide biosynthetic process
AWV81_RS20375	COG1309	transcriptional regulator
AWV81_RS20385	COG3162	membrane
AWV81_RS20390	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWV81_RS20395	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AWV81_RS20400	COG2837	iron assimilation
AWV81_RS20405	COG2822	iron ion transport
AWV81_RS20410	COG0672	)-iron permease
AWV81_RS20415	COG0352	thiamine-phosphate diphosphorylase activity
AWV81_RS20420	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AWV81_RS20425	COG0583	DNA-binding transcription factor activity
AWV81_RS20430	COG1380	Effector of murein hydrolase LrgA
AWV81_RS20435	COG1346	cytolysis
AWV81_RS20440	COG2814	Major facilitator Superfamily
AWV81_RS20445	COG4895	conserved protein (DUF2196)
AWV81_RS20450	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AWV81_RS20455	COG0346	lactoylglutathione lyase activity
AWV81_RS20470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWV81_RS20475	COG1404	Belongs to the peptidase S8 family
AWV81_RS20480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_RS20480	COG1263	PTS System
AWV81_RS20485	COG3711	transcriptional antiterminator
AWV81_RS20490	COG1442	glycosyl transferase family 8
AWV81_RS20495	COG5522	Integral membrane protein (intg_mem_TP0381)
AWV81_RS20500	COG1846	Transcriptional regulator
AWV81_RS20505	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWV81_RS20510	COG2234	aminopeptidase activity
AWV81_RS20515	COG2357	RelA SpoT domain protein
AWV81_RS20525	COG2801	Transposase and inactivated derivatives
AWV81_RS20530	COG1575	Belongs to the MenA family. Type 1 subfamily
AWV81_RS20545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWV81_RS20550	COG1696	Membrane protein involved in D-alanine export
AWV81_RS20555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWV81_RS20560	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AWV81_RS20570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWV81_RS20575	COG1486	melibiose metabolic process
AWV81_RS20580	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWV81_RS20585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWV81_RS20590	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWV81_RS20595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_RS20595	COG3711	transcriptional antiterminator
AWV81_RS20605	COG2094	Belongs to the DNA glycosylase MPG family
AWV81_RS20610	COG0753	catalase activity
AWV81_RS20615	COG2814	Major facilitator Superfamily
AWV81_RS20620	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AWV81_RS20625	COG1131	(ABC) transporter
AWV81_RS20645	COG1595	DNA-templated transcription, initiation
AWV81_RS20650	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AWV81_RS20655	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AWV81_RS20660	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AWV81_RS20665	COG4988	ABC transporter
AWV81_RS20670	COG1294	oxidase, subunit
AWV81_RS20675	COG1271	oxidase subunit
AWV81_RS20680	COG3493	citrate carrier protein
AWV81_RS20685	COG0501	Belongs to the peptidase M48B family
AWV81_RS20695	COG0726	polysaccharide deacetylase
AWV81_RS20700	COG3842	ATPase activity
AWV81_RS20705	COG2508	Transcriptional regulator
AWV81_RS20710	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_RS20715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWV81_RS20725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AWV81_RS20735	COG4585	Histidine kinase
AWV81_RS20740	COG2197	response regulator
AWV81_RS20745	COG2195	Cleaves the N-terminal amino acid of tripeptides
AWV81_RS20760	COG4894	glucomannan catabolic process
AWV81_RS20765	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWV81_RS20770	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWV81_RS20775	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS20780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AWV81_RS20785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AWV81_RS20790	COG2610	gluconate transmembrane transporter activity
AWV81_RS20800	COG0500	methyltransferase
AWV81_RS20805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWV81_RS20820	COG0693	protein deglycase activity
AWV81_RS20820	COG0753	catalase activity
AWV81_RS20825	COG2851	Citrate transporter
AWV81_RS20830	COG2273	Hydrolase Family 16
AWV81_RS20835	COG3711	transcriptional antiterminator
AWV81_RS20845	COG2270	Major facilitator Superfamily
AWV81_RS20850	COG0513	Belongs to the DEAD box helicase family
AWV81_RS20855	COG3401	FG-GAP repeat protein
AWV81_RS20855	COG2755	lipolytic protein G-D-S-L family
AWV81_RS20970	COG0697	spore germination
AWV81_RS20985	COG0589	response to stress
AWV81_RS20995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_RS20995	COG1263	PTS System
AWV81_RS20995	COG2190	(PTS) system
AWV81_RS21005	COG5444	nuclease activity
AWV81_RS21015	COG5444	nuclease activity
AWV81_RS21035	COG0494	nUDIX hydrolase
AWV81_RS21040	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AWV81_RS21045	COG3507	Belongs to the glycosyl hydrolase 43 family
AWV81_RS21050	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AWV81_RS21055	COG0833	amino acid
AWV81_RS21060	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AWV81_RS21065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWV81_RS21070	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AWV81_RS21075	COG2390	Transcriptional regulator
AWV81_RS21085	COG3192	ethanolamine utilization protein
AWV81_RS21090	COG2079	MmgE PrpD family protein
AWV81_RS21095	COG1473	amidohydrolase
AWV81_RS21100	COG1126	abc transporter atp-binding protein
AWV81_RS21105	COG0765	amino acid transport
AWV81_RS21110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWV81_RS21115	COG0456	acetyltransferase
AWV81_RS21120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWV81_RS21125	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AWV81_RS21130	COG0561	phosphatase activity
AWV81_RS21160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWV81_RS21165	COG5294	Protein conserved in bacteria
AWV81_RS21180	COG2205	protein histidine kinase activity
AWV81_RS21185	COG0745	RESPONSE REGULATOR receiver
AWV81_RS21190	COG0191	fructose-bisphosphate aldolase activity
AWV81_RS21195	COG1082	Xylose isomerase domain protein TIM barrel
AWV81_RS21200	COG1082	Xylose isomerase domain protein TIM barrel
AWV81_RS21205	COG0673	inositol 2-dehydrogenase activity
AWV81_RS21210	COG2814	Major facilitator Superfamily
AWV81_RS21215	COG1082	Xylose isomerase domain protein TIM barrel
AWV81_RS21220	COG3962	Belongs to the TPP enzyme family
AWV81_RS21225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWV81_RS21245	COG1349	DNA-binding transcription factor activity
AWV81_RS21250	COG0667	Aldo Keto reductase
AWV81_RS21280	COG0326	Molecular chaperone. Has ATPase activity
AWV81_RS21335	COG1917	Cupin 2, conserved barrel domain protein
AWV81_RS21340	COG1309	transcriptional regulator
AWV81_RS21345	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_RS21350	COG1846	Transcriptional regulator
AWV81_RS21355	COG1380	Effector of murein hydrolase LrgA
AWV81_RS21360	COG1346	cytolysis
AWV81_RS21365	COG5039	Polysaccharide pyruvyl transferase
AWV81_RS21370	COG1929	Belongs to the glycerate kinase type-1 family
AWV81_RS21375	COG1802	Transcriptional regulator
AWV81_RS21380	COG1070	Carbohydrate kinase
AWV81_RS21385	COG2610	gluconate transmembrane transporter activity
AWV81_RS21390	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AWV81_RS21395	COG0450	alkyl hydroperoxide reductase
AWV81_RS21400	COG3634	alkyl hydroperoxide reductase activity
AWV81_RS21405	COG2723	6-phospho-beta-galactosidase activity
AWV81_RS21420	COG2188	Transcriptional regulator
AWV81_RS21430	COG1131	(ABC) transporter
AWV81_RS21435	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AWV81_RS21450	COG0071	Belongs to the small heat shock protein (HSP20) family
AWV81_RS21480	COG0210	DNA helicase
AWV81_RS21510	COG2963	transposase activity
AWV81_RS21545	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AWV81_RS21555	COG1063	alcohol dehydrogenase
AWV81_RS21575	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AWV81_RS21580	COG0456	acetyltransferase
AWV81_RS21585	COG0457	Tetratricopeptide repeat
AWV81_RS21595	COG0010	Belongs to the arginase family
AWV81_RS21600	COG0833	amino acid
AWV81_RS21605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWV81_RS21625	COG5658	integral membrane protein
AWV81_RS21630	COG0640	Transcriptional regulator
AWV81_RS21635	COG3829	transcription factor binding
AWV81_RS21645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWV81_RS21650	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AWV81_RS21655	COG4853	Protein conserved in bacteria
AWV81_RS21660	COG4863	YycH protein
AWV81_RS21665	COG5002	protein histidine kinase activity
AWV81_RS21670	COG0745	RESPONSE REGULATOR receiver
AWV81_RS21700	COG0346	lactoylglutathione lyase activity
AWV81_RS21705	COG0305	Participates in initiation and elongation during chromosome replication
AWV81_RS21725	COG3093	addiction module antidote protein HigA
AWV81_RS21730	COG2807	transmembrane transport
AWV81_RS21735	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWV81_RS21740	COG0359	binds to the 23S rRNA
AWV81_RS21745	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AWV81_RS21750	COG4241	membrane
AWV81_RS21765	COG1733	regulation of RNA biosynthetic process
AWV81_RS21770	COG1227	inorganic diphosphatase activity
AWV81_RS21785	COG2271	Major facilitator Superfamily
AWV81_RS21790	COG0789	Transcriptional regulator
AWV81_RS21790	COG4978	Transcriptional regulator
AWV81_RS21800	COG4319	ketosteroid isomerase
AWV81_RS21805	COG1357	PFAM Pentapeptide repeats (8 copies)
AWV81_RS21810	COG2814	Major facilitator Superfamily
AWV81_RS21820	COG1846	Transcriptional regulator
AWV81_RS21825	COG2153	protein acetylation
AWV81_RS21830	COG2364	Membrane
AWV81_RS21835	COG0456	acetyltransferase
AWV81_RS21840	COG2315	Protein conserved in bacteria
AWV81_RS21845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AWV81_RS21850	COG1331	Highly conserved protein containing a thioredoxin domain
AWV81_RS21855	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AWV81_RS21860	COG1331	Highly conserved protein containing a thioredoxin domain
AWV81_RS21865	COG1266	CAAX protease self-immunity
AWV81_RS21870	COG2814	Major facilitator Superfamily
AWV81_RS21870	COG0477	Major facilitator Superfamily
AWV81_RS21875	COG0346	lactoylglutathione lyase activity
AWV81_RS21880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWV81_RS21885	COG0542	response to heat
AWV81_RS21895	COG1609	Transcriptional regulator
AWV81_RS21900	COG0708	Exodeoxyribonuclease III
AWV81_RS21905	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AWV81_RS21910	COG0629	single-stranded DNA binding
AWV81_RS21915	COG0360	Binds together with S18 to 16S ribosomal RNA
AWV81_RS21920	COG0012	GTP binding
AWV81_RS21925	COG0243	molybdopterin cofactor binding
AWV81_RS21930	COG4481	Protein conserved in bacteria
AWV81_RS21935	COG3949	Membrane
AWV81_RS21945	COG1475	DNA binding
AWV81_RS21950	COG1192	Involved in chromosome partitioning
AWV81_RS21960	COG1475	DNA binding
AWV81_RS21965	COG0357	Ribosomal RNA small subunit methyltransferase G
AWV81_RS21970	COG0445	tRNA wobble uridine modification
AWV81_RS21975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWV81_RS21980	COG1847	R3H domain protein
AWV81_RS21985	COG0706	membrane insertase activity
AWV81_RS21990	COG0594	ribonuclease P activity
AWV81_RS22065	COG0187	DNA topoisomerase II activity
AWV81_RS22170	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWV81_RS22230	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AWV81_RS22400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWV81_RS22430	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site