locus-tag	class	description
B4067_RS00020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B4067_RS00030	COG3209	COG3209 Rhs family protein
B4067_RS00040	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B4067_RS00045	COG0398	Pfam SNARE associated Golgi protein
B4067_RS00050	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS00050	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4067_RS00055	COG2755	lipolytic protein G-D-S-L family
B4067_RS00070	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
B4067_RS00075	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B4067_RS00080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B4067_RS00085	COG1534	Rna-binding protein
B4067_RS00090	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B4067_RS00095	COG1713	HD superfamily hydrolase involved in NAD metabolism
B4067_RS00100	COG0799	negative regulation of ribosome biogenesis
B4067_RS00105	COG2226	methyltransferase
B4067_RS00110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B4067_RS00115	COG1555	photosystem II stabilization
B4067_RS00115	COG1596	polysaccharide export
B4067_RS00120	COG2131	deaminase
B4067_RS00125	COG2333	competence protein COMEC
B4067_RS00125	COG0658	competence protein
B4067_RS00135	COG1466	dna polymerase III delta subunit
B4067_RS00140	COG0268	Binds directly to 16S ribosomal RNA
B4067_RS00145	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B4067_RS00150	COG0860	N-Acetylmuramoyl-L-alanine amidase
B4067_RS00160	COG0481	GTPase activity
B4067_RS00165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B4067_RS00170	COG1420	regulation of RNA biosynthetic process
B4067_RS00175	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B4067_RS00180	COG0443	Heat shock 70 kDa protein
B4067_RS00185	COG0484	heat shock protein binding
B4067_RS00190	COG2264	protein methyltransferase activity
B4067_RS00195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B4067_RS00200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B4067_RS00205	COG1283	sodium-dependent phosphate transmembrane transporter activity
B4067_RS00215	COG1610	YqeY-like protein
B4067_RS00220	COG1030	water channel activity
B4067_RS00225	COG4864	UPF0365 protein
B4067_RS00240	COG0561	phosphatase activity
B4067_RS00245	COG1702	phosphate starvation-inducible protein PhoH
B4067_RS00255	COG1480	7TM receptor with intracellular HD hydrolase
B4067_RS00260	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B4067_RS00265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B4067_RS00270	COG0295	cytidine deaminase activity
B4067_RS00275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B4067_RS00285	COG1381	Involved in DNA repair and RecF pathway recombination
B4067_RS00290	COG0752	glycyl-tRNA synthetase alpha subunit
B4067_RS00295	COG0751	glycine-tRNA ligase activity
B4067_RS00300	COG0517	IMP dehydrogenase activity
B4067_RS00305	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B4067_RS00310	COG1671	Belongs to the UPF0178 family
B4067_RS00315	COG0358	DNA primase activity
B4067_RS00320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B4067_RS00325	COG2010	Cytochrome c
B4067_RS00330	COG2384	SAM-dependent methyltransferase
B4067_RS00335	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B4067_RS00340	COG1388	LysM domain
B4067_RS00345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B4067_RS00350	COG0113	porphobilinogen synthase activity
B4067_RS00355	COG1587	Uroporphyrinogen-III synthase
B4067_RS00360	COG0181	hydroxymethylbilane synthase activity
B4067_RS00365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B4067_RS00370	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B4067_RS00380	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B4067_RS00385	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B4067_RS00390	COG1067	ATP-dependent peptidase activity
B4067_RS00390	COG0470	DNA polymerase III
B4067_RS00395	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B4067_RS00400	COG0544	peptidyl-prolyl cis-trans isomerase activity
B4067_RS00405	COG1477	protein flavinylation
B4067_RS00405	COG0457	Tetratricopeptide repeat
B4067_RS00410	COG0066	3-isopropylmalate dehydratase activity
B4067_RS00415	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B4067_RS00420	COG0473	3-isopropylmalate dehydrogenase activity
B4067_RS00425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B4067_RS00430	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B4067_RS00435	COG0440	acetolactate synthase activity
B4067_RS00440	COG0028	Belongs to the TPP enzyme family
B4067_RS00450	COG0454	-acetyltransferase
B4067_RS00460	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
B4067_RS00470	COG0622	Phosphoesterase
B4067_RS00475	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B4067_RS00480	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B4067_RS00485	COG5401	PFAM Sporulation and spore germination
B4067_RS00490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B4067_RS00495	COG1846	Transcriptional regulator
B4067_RS00500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B4067_RS00520	COG1388	LysM domain
B4067_RS00520	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS00520	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4067_RS00525	COG4824	toxin secretion phage lysis holin
B4067_RS00575	COG1388	LysM domain
B4067_RS00575	COG0791	NLP P60 protein
B4067_RS00580	COG3953	SLT domain
B4067_RS00580	COG5280	Phage tail tape measure protein TP901
B4067_RS00645	COG5484	DNA packaging
B4067_RS00670	COG0735	belongs to the Fur family
B4067_RS00675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B4067_RS00680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B4067_RS00685	COG4129	membrane
B4067_RS00690	COG1132	(ABC) transporter
B4067_RS00695	COG3557	Belongs to the UPF0374 family
B4067_RS00710	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS00720	COG1194	a g-specific adenine glycosylase
B4067_RS00725	COG1988	membrane-bound metal-dependent
B4067_RS00730	COG4485	Bacterial membrane protein, YfhO
B4067_RS00735	COG0463	Glycosyl transferase, family 2
B4067_RS00740	COG0596	Alpha beta hydrolase
B4067_RS00745	COG5658	integral membrane protein
B4067_RS00750	COG3103	Sh3 type 3 domain protein
B4067_RS00755	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B4067_RS00760	COG1404	Belongs to the peptidase S8 family
B4067_RS00765	COG1366	Belongs to the anti-sigma-factor antagonist family
B4067_RS00775	COG1122	ATPase activity
B4067_RS00780	COG4721	ABC-type cobalt transport system, permease component
B4067_RS00790	COG0745	RESPONSE REGULATOR receiver
B4067_RS00795	COG3850	Histidine kinase
B4067_RS00795	COG5002	protein histidine kinase activity
B4067_RS00800	COG3212	peptidase
B4067_RS00805	COG3212	peptidase
B4067_RS00825	COG2239	Acts as a magnesium transporter
B4067_RS00830	COG0789	Transcriptional regulator
B4067_RS00845	COG1846	Transcriptional regulator
B4067_RS00855	COG0726	polysaccharide deacetylase
B4067_RS00860	COG1408	metallophosphoesterase
B4067_RS00870	COG0463	Glycosyl transferase, family 2
B4067_RS00875	COG3285	dna ligase
B4067_RS00875	COG1793	dna ligase
B4067_RS00880	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B4067_RS00890	COG0586	Pfam SNARE associated Golgi protein
B4067_RS00895	COG0861	Integral membrane protein TerC family
B4067_RS00900	COG1191	sigma factor activity
B4067_RS00920	COG0501	Belongs to the peptidase M48B family
B4067_RS00925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B4067_RS00940	COG3594	Acyltransferase
B4067_RS00945	COG5002	protein histidine kinase activity
B4067_RS00950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B4067_RS00960	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B4067_RS00965	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
B4067_RS00970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B4067_RS00975	COG0436	Aminotransferase
B4067_RS00980	COG1850	ribulose-bisphosphate carboxylase activity
B4067_RS00985	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
B4067_RS00990	COG0235	Class ii aldolase
B4067_RS00995	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B4067_RS01000	COG3339	Conserved Protein
B4067_RS01015	COG3852	Histidine kinase
B4067_RS01020	COG1846	Transcriptional regulator
B4067_RS01025	COG1360	Flagellar Motor Protein
B4067_RS01030	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B4067_RS01035	COG0542	response to heat
B4067_RS01040	COG3949	Membrane
B4067_RS01045	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B4067_RS01050	COG0720	synthase
B4067_RS01055	COG0602	queuosine metabolic process
B4067_RS01060	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B4067_RS01065	COG1733	regulation of RNA biosynthetic process
B4067_RS01070	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS01075	COG1388	LysM domain
B4067_RS01075	COG4641	Protein conserved in bacteria
B4067_RS01080	COG1388	LysM domain
B4067_RS01085	COG3858	chitin binding
B4067_RS01095	COG4873	Protein conserved in bacteria
B4067_RS01110	COG3773	Cell wall hydrolase
B4067_RS01115	COG2244	polysaccharide biosynthetic process
B4067_RS01120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4067_RS01125	COG2217	Heavy metal translocating P-type atpase
B4067_RS01135	COG0006	proline dipeptidase activity
B4067_RS01145	COG1609	Transcriptional regulator
B4067_RS01150	COG3711	transcriptional antiterminator
B4067_RS01155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4067_RS01155	COG1263	PTS System
B4067_RS01155	COG2190	(PTS) system
B4067_RS01160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B4067_RS01165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B4067_RS01175	COG1533	DNA photolyase activity
B4067_RS01180	COG0456	acetyltransferase
B4067_RS01185	COG0840	transmembrane signaling receptor activity
B4067_RS01190	COG2084	Dehydrogenase
B4067_RS01195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B4067_RS01200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B4067_RS01200	COG1321	iron dependent repressor
B4067_RS01205	COG1121	(ABC) transporter
B4067_RS01210	COG0803	Belongs to the bacterial solute-binding protein 9 family
B4067_RS01215	COG4948	Mandelate Racemase Muconate Lactonizing
B4067_RS01220	COG0318	PFAM AMP-dependent synthetase and ligase
B4067_RS01225	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B4067_RS01230	COG0596	Alpha beta hydrolase
B4067_RS01235	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B4067_RS01240	COG1169	isochorismate synthase
B4067_RS01245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B4067_RS01250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B4067_RS01255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B4067_RS01260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B4067_RS01265	COG0438	transferase activity, transferring glycosyl groups
B4067_RS01275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B4067_RS01280	COG0438	transferase activity, transferring glycosyl groups
B4067_RS01285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B4067_RS01290	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
B4067_RS01295	COG0668	transmembrane transport
B4067_RS01300	COG0535	radical SAM domain protein
B4067_RS01310	COG0726	polysaccharide deacetylase
B4067_RS01315	COG2084	Dehydrogenase
B4067_RS01320	COG0598	Magnesium transport protein CorA
B4067_RS01325	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B4067_RS01330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B4067_RS01345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B4067_RS01350	COG4637	Psort location Cytoplasmic, score
B4067_RS01360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B4067_RS01365	COG0022	dehydrogenase e1 component
B4067_RS01370	COG0508	dehydrogenase complex catalyzes the overall conversion of
B4067_RS01375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B4067_RS01380	COG3284	Transcriptional regulator
B4067_RS01390	COG1742	UPF0060 membrane protein
B4067_RS01410	COG4842	Belongs to the WXG100 family
B4067_RS01415	COG1486	melibiose metabolic process
B4067_RS01420	COG1737	Transcriptional regulator
B4067_RS01425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4067_RS01425	COG1263	PTS System
B4067_RS01430	COG1132	(ABC) transporter
B4067_RS01435	COG1132	(ABC) transporter
B4067_RS01440	COG2259	Doxx family
B4067_RS01445	COG2514	catechol 2,3-dioxygenase activity
B4067_RS01450	COG4977	sequence-specific DNA binding
B4067_RS01450	COG1917	Cupin 2, conserved barrel domain protein
B4067_RS01455	COG2814	Major facilitator Superfamily
B4067_RS01460	COG1082	Xylose isomerase domain protein TIM barrel
B4067_RS01465	COG0673	inositol 2-dehydrogenase activity
B4067_RS01470	COG4585	Histidine kinase
B4067_RS01475	COG2197	response regulator
B4067_RS01480	COG1131	(ABC) transporter
B4067_RS01485	COG0842	Transport permease protein
B4067_RS01485	COG1511	domain protein
B4067_RS01490	COG0842	Transport permease protein
B4067_RS01500	COG1695	Transcriptional regulator
B4067_RS01510	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
B4067_RS01515	COG2318	DinB family
B4067_RS01520	COG2814	Major facilitator Superfamily
B4067_RS01525	COG1846	Transcriptional regulator
B4067_RS01530	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B4067_RS01530	COG0392	lysyltransferase activity
B4067_RS01535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4067_RS01540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4067_RS01545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4067_RS01550	COG0384	phenazine biosynthesis protein PhzF
B4067_RS01555	COG0778	Nitroreductase
B4067_RS01565	COG0756	dUTP diphosphatase activity
B4067_RS01575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4067_RS01580	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B4067_RS01590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B4067_RS01595	COG1372	Participates in initiation and elongation during chromosome replication
B4067_RS01595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B4067_RS01600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B4067_RS01600	COG1372	Participates in initiation and elongation during chromosome replication
B4067_RS01605	COG1780	Probably involved in ribonucleotide reductase function
B4067_RS01615	COG4948	Mandelate Racemase Muconate Lactonizing
B4067_RS01620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4067_RS01625	COG1809	phosphosulfolactate synthase activity
B4067_RS01630	COG2045	Belongs to the ComB family
B4067_RS01645	COG0529	Catalyzes the synthesis of activated sulfate
B4067_RS01650	COG2267	carboxylic ester hydrolase activity
B4067_RS01655	COG1357	PFAM Pentapeptide repeats (8 copies)
B4067_RS01660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4067_RS01665	COG1279	arginine transmembrane transporter activity
B4067_RS01670	COG2318	DinB family
B4067_RS01675	COG0673	inositol 2-dehydrogenase activity
B4067_RS01680	COG1609	Transcriptional regulator
B4067_RS01685	COG1917	Cupin 2, conserved barrel domain protein
B4067_RS01685	COG2207	Transcriptional regulator
B4067_RS01690	COG0534	Mate efflux family protein
B4067_RS01695	COG1562	ergosterol biosynthetic process
B4067_RS01700	COG0367	asparagine synthase
B4067_RS01710	COG1404	Belongs to the peptidase S8 family
B4067_RS01720	COG0179	Fumarylacetoacetate (FAA) hydrolase
B4067_RS01725	COG5337	Spore coat protein CotH
B4067_RS01770	COG1403	HNH endonuclease
B4067_RS01775	COG0419	ATPase involved in DNA repair
B4067_RS01780	COG0420	3'-5' exonuclease activity
B4067_RS01785	COG1074	ATP-dependent DNA helicase activity
B4067_RS01790	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
B4067_RS01795	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
B4067_RS01805	COG4533	DNA binding
B4067_RS01810	COG2814	Major facilitator Superfamily
B4067_RS01810	COG0477	Major facilitator Superfamily
B4067_RS01815	COG3180	Ammonia monooxygenase
B4067_RS01820	COG1609	Transcriptional regulator
B4067_RS01830	COG0561	phosphatase activity
B4067_RS01835	COG0673	inositol 2-dehydrogenase activity
B4067_RS01840	COG0738	Major facilitator superfamily
B4067_RS01845	COG1846	Transcriptional regulator
B4067_RS01850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B4067_RS01855	COG0681	Belongs to the peptidase S26 family
B4067_RS01860	COG0398	Pfam SNARE associated Golgi protein
B4067_RS01875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B4067_RS01885	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS01890	COG4903	ComK protein
B4067_RS01900	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS01910	COG0840	transmembrane signaling receptor activity
B4067_RS01915	COG1268	BioY protein
B4067_RS01920	COG0318	PFAM AMP-dependent synthetase and ligase
B4067_RS01925	COG0183	Belongs to the thiolase family
B4067_RS01930	COG0406	alpha-ribazole phosphatase activity
B4067_RS01935	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B4067_RS01940	COG0604	alcohol dehydrogenase
B4067_RS01945	COG0456	acetyltransferase
B4067_RS01950	COG1404	Belongs to the peptidase S8 family
B4067_RS01955	COG0501	Belongs to the peptidase M48B family
B4067_RS01965	COG0318	PFAM AMP-dependent synthetase and ligase
B4067_RS01970	COG0702	epimerase
B4067_RS01975	COG0095	Lipoate-protein ligase
B4067_RS01980	COG1234	tRNA 3'-trailer cleavage
B4067_RS01990	COG1301	dicarboxylic acid transport
B4067_RS01995	COG4405	Protein conserved in bacteria
B4067_RS02000	COG1363	Peptidase, m42
B4067_RS02010	COG4377	Putative membrane peptidase family (DUF2324)
B4067_RS02015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B4067_RS02020	COG1511	domain protein
B4067_RS02025	COG1309	transcriptional regulator
B4067_RS02030	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B4067_RS02035	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B4067_RS02040	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B4067_RS02045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B4067_RS02050	COG2329	Antibiotic biosynthesis monooxygenase
B4067_RS02060	COG3069	C4-dicarboxylate transmembrane transporter activity
B4067_RS02065	COG1473	amidohydrolase
B4067_RS02075	COG4473	ABC transporter
B4067_RS02080	COG1131	(ABC) transporter
B4067_RS02085	COG0537	adenosine 5'-monophosphoramidase activity
B4067_RS02090	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B4067_RS02105	COG4980	gas vesicle protein
B4067_RS02110	COG1846	Transcriptional regulator
B4067_RS02135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B4067_RS02145	COG3481	metal-dependent phosphohydrolase, HD sub domain
B4067_RS02150	COG4717	serine-type aminopeptidase activity
B4067_RS02155	COG0420	3'-5' exonuclease activity
B4067_RS02160	COG1668	transmembrane transport
B4067_RS02165	COG4152	abc transporter atp-binding protein
B4067_RS02175	COG1024	Enoyl-CoA hydratase
B4067_RS02185	COG0490	domain, Protein
B4067_RS02190	COG0475	glutathione-regulated potassium exporter activity
B4067_RS02195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B4067_RS02200	COG0561	phosphatase activity
B4067_RS02205	COG4335	DNA alkylation repair
B4067_RS02210	COG3679	Belongs to the UPF0342 family
B4067_RS02215	COG4399	Belongs to the UPF0754 family
B4067_RS02220	COG0189	ligase activity
B4067_RS02225	COG0189	ligase activity
B4067_RS02245	COG1132	(ABC) transporter
B4067_RS02250	COG1132	(ABC) transporter
B4067_RS02260	COG0589	response to stress
B4067_RS02265	COG1757	Na H antiporter
B4067_RS02270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B4067_RS02275	COG0726	polysaccharide deacetylase
B4067_RS02280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B4067_RS02285	COG0668	transmembrane transport
B4067_RS02295	COG0584	glycerophosphoryl diester phosphodiesterase
B4067_RS02300	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B4067_RS02305	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B4067_RS02310	COG1253	flavin adenine dinucleotide binding
B4067_RS02315	COG0436	Aminotransferase
B4067_RS02320	COG0789	Transcriptional regulator
B4067_RS02325	COG1253	flavin adenine dinucleotide binding
B4067_RS02330	COG0204	Acyl-transferase
B4067_RS02335	COG0667	Aldo Keto reductase
B4067_RS02340	COG1595	DNA-templated transcription, initiation
B4067_RS02355	COG0456	acetyltransferase
B4067_RS02360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4067_RS02365	COG0733	neurotransmitter:sodium symporter activity
B4067_RS02370	COG0531	amino acid
B4067_RS02375	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS02380	COG0372	Belongs to the citrate synthase family
B4067_RS02385	COG0583	DNA-binding transcription factor activity
B4067_RS02390	COG0791	NLP P60 protein
B4067_RS02390	COG1388	LysM domain
B4067_RS02395	COG1785	Belongs to the alkaline phosphatase family
B4067_RS02400	COG2719	SpoVR family
B4067_RS02405	COG0668	transmembrane transport
B4067_RS02410	COG1959	2 iron, 2 sulfur cluster binding
B4067_RS02415	COG0791	NLP P60 protein
B4067_RS02415	COG1388	LysM domain
B4067_RS02430	COG0431	NADPH-dependent FMN reductase
B4067_RS02435	COG2197	response regulator
B4067_RS02440	COG2203	Gaf domain
B4067_RS02440	COG4585	Histidine kinase
B4067_RS02445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B4067_RS02450	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B4067_RS02455	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B4067_RS02460	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B4067_RS02465	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
B4067_RS02470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B4067_RS02475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B4067_RS02475	COG3153	acetyltransferase
B4067_RS02480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B4067_RS02485	COG0517	IMP dehydrogenase activity
B4067_RS02495	COG0564	pseudouridine synthase activity
B4067_RS02500	COG3764	Sortase (surface protein transpeptidase)
B4067_RS02505	COG1525	nuclease
B4067_RS02505	COG0737	Belongs to the 5'-nucleotidase family
B4067_RS02505	COG4085	toxin activity
B4067_RS02510	COG5577	PFAM Coat F domain
B4067_RS02530	COG1823	symporter activity
B4067_RS02540	COG1464	Belongs to the NlpA lipoprotein family
B4067_RS02545	COG1278	Cold shock
B4067_RS02550	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B4067_RS02555	COG1131	(ABC) transporter
B4067_RS02560	COG1131	(ABC) transporter
B4067_RS02565	COG1725	Transcriptional regulator
B4067_RS02580	COG0655	NAD(P)H dehydrogenase (quinone) activity
B4067_RS02585	COG2814	Major facilitator Superfamily
B4067_RS02590	COG1566	PFAM secretion protein HlyD family protein
B4067_RS02605	COG2718	Belongs to the UPF0229 family
B4067_RS02610	COG2766	serine protein kinase
B4067_RS02620	COG2197	response regulator
B4067_RS02625	COG2050	protein possibly involved in aromatic compounds catabolism
B4067_RS02630	COG1320	monovalent cation:proton antiporter activity
B4067_RS02635	COG2212	antiporter activity
B4067_RS02640	COG1863	multisubunit Na H antiporter MnhE subunit
B4067_RS02645	COG0651	ATP synthesis coupled electron transport
B4067_RS02650	COG1006	Multisubunit Na H antiporter MnhC subunit
B4067_RS02655	COG2111	Na H antiporter
B4067_RS02660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B4067_RS02660	COG2111	Na H antiporter
B4067_RS02670	COG3493	citrate carrier protein
B4067_RS02675	COG1079	Belongs to the binding-protein-dependent transport system permease family
B4067_RS02680	COG4603	Belongs to the binding-protein-dependent transport system permease family
B4067_RS02685	COG3845	ABC transporter
B4067_RS02690	COG1744	ABC transporter substrate-binding protein PnrA-like
B4067_RS02695	COG4565	transcriptional regulatory protein
B4067_RS02700	COG3290	protein histidine kinase activity
B4067_RS02710	COG3011	Protein conserved in bacteria
B4067_RS02715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B4067_RS02720	COG2814	Major facilitator Superfamily
B4067_RS02730	COG5018	Exonuclease
B4067_RS02740	COG2205	protein histidine kinase activity
B4067_RS02745	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B4067_RS02755	COG3328	transposase activity
B4067_RS02765	COG0697	spore germination
B4067_RS02770	COG0583	DNA-binding transcription factor activity
B4067_RS02775	COG3739	integral membrane protein
B4067_RS02780	COG3655	Transcriptional regulator
B4067_RS02790	COG2720	vancomycin resistance protein
B4067_RS02820	COG2135	peptidase activity
B4067_RS02830	COG3619	membrane
B4067_RS02835	COG4305	rare lipoprotein A
B4067_RS02840	COG2368	4-hydroxyphenylacetate
B4067_RS02845	COG0840	transmembrane signaling receptor activity
B4067_RS02845	COG5278	phosphoserine phosphatase activity
B4067_RS02865	COG2234	aminopeptidase activity
B4067_RS02870	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B4067_RS02875	COG1846	Transcriptional regulator
B4067_RS02880	COG5522	Integral membrane protein (intg_mem_TP0381)
B4067_RS02885	COG1442	glycosyl transferase family 8
B4067_RS02890	COG3711	transcriptional antiterminator
B4067_RS02895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4067_RS02895	COG1263	PTS System
B4067_RS02905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B4067_RS02915	COG0346	lactoylglutathione lyase activity
B4067_RS02920	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B4067_RS02925	COG4895	conserved protein (DUF2196)
B4067_RS02930	COG2814	Major facilitator Superfamily
B4067_RS02935	COG1346	cytolysis
B4067_RS02940	COG1380	Effector of murein hydrolase LrgA
B4067_RS02945	COG0583	DNA-binding transcription factor activity
B4067_RS02950	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
B4067_RS02955	COG0352	thiamine-phosphate diphosphorylase activity
B4067_RS02960	COG0672	)-iron permease
B4067_RS02965	COG2822	iron ion transport
B4067_RS02970	COG2837	iron assimilation
B4067_RS02975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B4067_RS02980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B4067_RS02985	COG3162	membrane
B4067_RS02995	COG1309	transcriptional regulator
B4067_RS03000	COG2246	polysaccharide biosynthetic process
B4067_RS03005	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
B4067_RS03010	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
B4067_RS03015	COG2261	transglycosylase associated protein
B4067_RS03020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B4067_RS03025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B4067_RS03030	COG1845	cytochrome c oxidase, subunit III
B4067_RS03035	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B4067_RS03045	COG0772	Belongs to the SEDS family
B4067_RS03050	COG0778	Nitroreductase
B4067_RS03055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B4067_RS03060	COG1404	Belongs to the peptidase S8 family
B4067_RS03070	COG3711	transcriptional antiterminator
B4067_RS03075	COG2116	formate transmembrane transporter activity
B4067_RS03080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4067_RS03080	COG1263	PTS System
B4067_RS03085	COG1621	beta-fructofuranosidase activity
B4067_RS03110	COG4195	phage-related replication protein
B4067_RS03115	COG5434	Belongs to the glycosyl hydrolase 28 family
B4067_RS03115	COG3420	alginic acid biosynthetic process
B4067_RS03145	COG1396	sequence-specific DNA binding
B4067_RS03180	COG1846	Transcriptional regulator
B4067_RS03220	COG3331	DNA recombination
B4067_RS03370	COG4824	toxin secretion phage lysis holin
B4067_RS03375	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS03375	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4067_RS03375	COG1388	LysM domain
B4067_RS03395	COG3853	Toxic anion resistance protein (TelA)
B4067_RS03405	COG0861	Integral membrane protein TerC family
B4067_RS03410	COG2310	stress, protein
B4067_RS03415	COG2310	stress, protein
B4067_RS03420	COG2310	stress, protein
B4067_RS03425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B4067_RS03430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B4067_RS03435	COG1121	(ABC) transporter
B4067_RS03440	COG0803	Belongs to the bacterial solute-binding protein 9 family
B4067_RS03450	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS03455	COG0457	Tetratricopeptide repeat
B4067_RS03460	COG1876	peptidase activity
B4067_RS03465	COG1595	DNA-templated transcription, initiation
B4067_RS03470	COG1595	DNA-templated transcription, initiation
B4067_RS03485	COG1668	transmembrane transport
B4067_RS03495	COG3279	Response regulator of the LytR AlgR family
B4067_RS03505	COG3012	SEC-C Motif Domain Protein
B4067_RS03505	COG1405	negative regulation of cell septum assembly
B4067_RS03510	COG1714	RDD family
B4067_RS03515	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
B4067_RS03520	COG0252	asparaginase activity
B4067_RS03525	COG1309	transcriptional regulator
B4067_RS03530	COG0477	Major facilitator Superfamily
B4067_RS03535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B4067_RS03540	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
B4067_RS03545	COG0805	protein transport
B4067_RS03550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B4067_RS03555	COG3540	Alkaline phosphatase
B4067_RS03565	COG2304	oxidoreductase activity
B4067_RS03570	COG3773	Cell wall hydrolase
B4067_RS03590	COG1131	(ABC) transporter
B4067_RS03595	COG2205	protein histidine kinase activity
B4067_RS03600	COG0745	RESPONSE REGULATOR receiver
B4067_RS03605	COG0697	spore germination
B4067_RS03620	COG2721	sulfolactate sulfo-lyase activity
B4067_RS03625	COG2186	Transcriptional regulator
B4067_RS03630	COG4948	Mandelate Racemase Muconate Lactonizing
B4067_RS03635	COG2271	Major facilitator Superfamily
B4067_RS03640	COG1012	belongs to the aldehyde dehydrogenase family
B4067_RS03645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B4067_RS03650	COG0784	Response regulator, receiver
B4067_RS03665	COG0833	amino acid
B4067_RS03670	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B4067_RS03675	COG1086	Polysaccharide biosynthesis protein
B4067_RS03680	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B4067_RS03685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B4067_RS03690	COG1846	Transcriptional regulator
B4067_RS03695	COG0534	Mate efflux family protein
B4067_RS03705	COG4698	Protein conserved in bacteria
B4067_RS03710	COG2755	lipolytic protein G-D-S-L family
B4067_RS03715	COG1999	signal sequence binding
B4067_RS03730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B4067_RS03735	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B4067_RS03740	COG1272	protein, Hemolysin III
B4067_RS03745	COG0204	Acyl-transferase
B4067_RS03750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B4067_RS03755	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B4067_RS03760	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B4067_RS03770	COG2136	Putative SAM-dependent methyltransferase
B4067_RS03770	COG2521	methyltransferase
B4067_RS03780	COG0129	dihydroxy-acid dehydratase activity
B4067_RS03785	COG1413	lyase activity
B4067_RS03790	COG1418	mRNA catabolic process
B4067_RS03795	COG0386	Belongs to the glutathione peroxidase family
B4067_RS03800	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B4067_RS03805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B4067_RS03810	COG1278	Cold shock
B4067_RS03830	COG0328	RNA-DNA hybrid ribonuclease activity
B4067_RS03835	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B4067_RS03840	COG0328	RNA-DNA hybrid ribonuclease activity
B4067_RS03850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B4067_RS03870	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B4067_RS03875	COG1755	Isoprenylcysteine carboxyl methyltransferase
B4067_RS03880	COG3424	synthase
B4067_RS03885	COG2233	PERMEase
B4067_RS03890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B4067_RS03895	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B4067_RS03905	COG0800	Aldolase
B4067_RS03910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B4067_RS03915	COG1609	Transcriptional regulator
B4067_RS03920	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
B4067_RS03925	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS03930	COG1199	ATP-dependent helicase activity
B4067_RS03940	COG0116	Belongs to the methyltransferase superfamily
B4067_RS03950	COG4474	Belongs to the UPF0398 family
B4067_RS03960	COG3359	exonuclease
B4067_RS03965	COG1205	dead DEAH box helicase
B4067_RS03965	COG1111	helicase
B4067_RS03970	COG2190	(PTS) system
B4067_RS03975	COG0071	Belongs to the small heat shock protein (HSP20) family
B4067_RS04010	COG3331	DNA recombination
B4067_RS04015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B4067_RS04015	COG4499	WXG100 protein secretion system (Wss), protein YukC
B4067_RS04025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B4067_RS04030	COG3935	DnaD domain protein
B4067_RS04035	COG0017	Asparaginyl-tRNA synthetase
B4067_RS04040	COG0436	Aminotransferase
B4067_RS04045	COG5353	protein conserved in bacteria
B4067_RS04055	COG1199	ATP-dependent helicase activity
B4067_RS04055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B4067_RS04060	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B4067_RS04065	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B4067_RS04070	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B4067_RS04075	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
B4067_RS04075	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
B4067_RS04080	COG0617	tRNA 3'-terminal CCA addition
B4067_RS04085	COG0438	transferase activity, transferring glycosyl groups
B4067_RS04090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B4067_RS04095	COG1803	Methylglyoxal synthase
B4067_RS04100	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B4067_RS04105	COG1694	Mazg nucleotide pyrophosphohydrolase
B4067_RS04110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4067_RS04120	COG4347	Protein of unknown function (DUF1405)
B4067_RS04125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B4067_RS04125	COG2010	Cytochrome c
B4067_RS04130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B4067_RS04135	COG0723	plastoquinol--plastocyanin reductase activity
B4067_RS04145	COG5582	Belongs to the UPF0302 family
B4067_RS04150	COG0457	Tetratricopeptide repeat
B4067_RS04155	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B4067_RS04160	COG0287	Prephenate dehydrogenase
B4067_RS04175	COG0133	tryptophan synthase activity
B4067_RS04180	COG0135	phosphoribosylanthranilate isomerase activity
B4067_RS04190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B4067_RS04195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B4067_RS04200	COG4401	Chorismate mutase type I
B4067_RS04205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B4067_RS04210	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B4067_RS04215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B4067_RS04225	COG0105	UTP biosynthetic process
B4067_RS04230	COG0142	geranyltranstransferase activity
B4067_RS04235	COG2226	methyltransferase
B4067_RS04240	COG0142	geranyltranstransferase activity
B4067_RS04250	COG0302	gtp cyclohydrolase
B4067_RS04255	COG0776	regulation of translation
B4067_RS04260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B4067_RS04275	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B4067_RS04280	COG1160	GTP binding
B4067_RS04305	COG1304	FMN binding
B4067_RS04310	COG0539	negative regulation of cytoplasmic translation
B4067_RS04315	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B4067_RS04325	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B4067_RS04330	COG2959	enzyme of heme biosynthesis
B4067_RS04335	COG3773	Cell wall hydrolase
B4067_RS04335	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS04340	COG2339	peptidase activity
B4067_RS04345	COG0492	ferredoxin-NADP+ reductase activity
B4067_RS04350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B4067_RS04355	COG4862	establishment of competence for transformation
B4067_RS04360	COG1408	metallophosphoesterase
B4067_RS04370	COG1388	LysM domain
B4067_RS04375	COG1266	CAAX protease self-immunity
B4067_RS04380	COG0514	ATP-dependent DNA helicase (RecQ)
B4067_RS04385	COG4955	Helix-turn-helix domain
B4067_RS04390	COG1141	Ferredoxin
B4067_RS04395	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B4067_RS04405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B4067_RS04410	COG0710	3-dehydroquinate dehydratase activity
B4067_RS04420	COG1595	DNA-templated transcription, initiation
B4067_RS04425	COG5002	protein histidine kinase activity
B4067_RS04430	COG0745	RESPONSE REGULATOR receiver
B4067_RS04435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B4067_RS04440	COG1333	cytochrome c biogenesis protein
B4067_RS04445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4067_RS04450	COG1187	pseudouridine synthase activity
B4067_RS04455	COG0700	Nucleoside recognition
B4067_RS04460	COG2715	membrane protein required for spore maturation
B4067_RS04465	COG1686	Belongs to the peptidase S11 family
B4067_RS04475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B4067_RS04480	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B4067_RS04485	COG1547	Domain of unknown function (DUF309)
B4067_RS04490	COG0456	acetyltransferase
B4067_RS04495	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B4067_RS04500	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B4067_RS04500	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B4067_RS04505	COG0307	riboflavin synthase, alpha
B4067_RS04510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B4067_RS04510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B4067_RS04520	COG0681	Belongs to the peptidase S26 family
B4067_RS04530	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
B4067_RS04560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B4067_RS04565	COG4086	secreted protein
B4067_RS04570	COG0019	diaminopimelate decarboxylase activity
B4067_RS04575	COG0697	spore germination
B4067_RS04590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B4067_RS04610	COG1191	sigma factor activity
B4067_RS04615	COG2172	sigma factor antagonist activity
B4067_RS04620	COG1366	Belongs to the anti-sigma-factor antagonist family
B4067_RS04625	COG1686	Belongs to the peptidase S11 family
B4067_RS04630	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B4067_RS04635	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B4067_RS04640	COG4974	Belongs to the 'phage' integrase family
B4067_RS04650	COG0735	belongs to the Fur family
B4067_RS04655	COG1300	Membrane
B4067_RS04665	COG0281	malic enzyme
B4067_RS04670	COG1757	Na H antiporter
B4067_RS04675	COG1027	Aspartate ammonia-lyase
B4067_RS04680	COG0252	asparaginase activity
B4067_RS04685	COG1396	sequence-specific DNA binding
B4067_RS04690	COG1379	DNA repair
B4067_RS04695	COG0494	nUDIX hydrolase
B4067_RS04705	COG0667	Aldo Keto reductase
B4067_RS04725	COG4918	Iron-sulphur cluster biosynthesis
B4067_RS04730	COG0456	acetyltransferase
B4067_RS04730	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B4067_RS04735	COG2329	Antibiotic biosynthesis monooxygenase
B4067_RS04740	COG0456	acetyltransferase
B4067_RS04750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B4067_RS04760	COG2211	Major facilitator Superfamily
B4067_RS04770	COG0346	lactoylglutathione lyase activity
B4067_RS04775	COG1072	(Pantothenic acid kinase))
B4067_RS04780	COG3048	D-serine ammonia-lyase activity
B4067_RS04785	COG0300	oxidoreductase activity
B4067_RS04790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4067_RS04795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B4067_RS04800	COG4187	Peptidase family M20/M25/M40
B4067_RS04805	COG1902	pentaerythritol trinitrate reductase activity
B4067_RS04810	COG0596	Alpha beta hydrolase
B4067_RS04820	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B4067_RS04825	COG2199	diguanylate cyclase activity
B4067_RS04825	COG2203	Gaf domain
B4067_RS04830	COG1956	GAF domain-containing protein
B4067_RS04835	COG1309	transcriptional regulator
B4067_RS04840	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B4067_RS04845	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
B4067_RS04850	COG1114	Component of the transport system for branched-chain amino acids
B4067_RS04855	COG1104	cysteine desulfurase activity
B4067_RS04860	COG0301	tRNA thio-modification
B4067_RS04870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B4067_RS04875	COG1574	metal-dependent hydrolase with the TIM-barrel fold
B4067_RS04880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B4067_RS04885	COG0616	signal peptide processing
B4067_RS04890	COG1714	RDD family
B4067_RS04900	COG3874	Sporulation protein YtfJ
B4067_RS04905	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B4067_RS04910	COG0827	DNA restriction-modification system
B4067_RS04915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B4067_RS04920	COG0521	Mo-molybdopterin cofactor biosynthetic process
B4067_RS04925	COG0137	argininosuccinate synthase activity
B4067_RS04930	COG0165	Argininosuccinate lyase
B4067_RS04940	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS04945	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B4067_RS04950	COG0583	DNA-binding transcription factor activity
B4067_RS04955	COG0454	-acetyltransferase
B4067_RS04960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B4067_RS04965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B4067_RS04970	COG0765	amino acid transport
B4067_RS04975	COG0765	amino acid transport
B4067_RS04980	COG1126	abc transporter atp-binding protein
B4067_RS04985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B4067_RS04990	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B4067_RS04995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B4067_RS05000	COG0196	riboflavin kinase activity
B4067_RS05010	COG0730	response to heat
B4067_RS05020	COG4109	DRTGG domain
B4067_RS05030	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B4067_RS05050	COG0587	DNA-directed DNA polymerase activity
B4067_RS05055	COG0281	malic enzyme
B4067_RS05060	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B4067_RS05065	COG0825	malonyl-CoA metabolic process
B4067_RS05070	COG0205	6-phosphofructokinase activity
B4067_RS05075	COG0469	pyruvate kinase activity
B4067_RS05080	COG3030	protein affecting phage T7 exclusion by the F plasmid
B4067_RS05085	COG0628	permease
B4067_RS05090	COG2707	UPF0756 membrane protein
B4067_RS05095	COG0372	Belongs to the citrate synthase family
B4067_RS05100	COG0538	isocitrate dehydrogenase activity
B4067_RS05105	COG0039	L-malate dehydrogenase activity
B4067_RS05110	COG0745	RESPONSE REGULATOR receiver
B4067_RS05115	COG5002	protein histidine kinase activity
B4067_RS05120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B4067_RS05120	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B4067_RS05125	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B4067_RS05140	COG0237	dephospho-CoA kinase activity
B4067_RS05145	COG0656	L-ascorbic acid biosynthetic process
B4067_RS05150	COG2814	Major facilitator Superfamily
B4067_RS05155	COG1733	regulation of RNA biosynthetic process
B4067_RS05160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B4067_RS05170	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B4067_RS05175	COG3611	Membrane attachment protein
B4067_RS05180	COG1484	DNA-dependent DNA replication
B4067_RS05185	COG0398	Pfam SNARE associated Golgi protein
B4067_RS05195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B4067_RS05200	COG1011	Hydrolase
B4067_RS05205	COG3275	phosphorelay sensor kinase activity
B4067_RS05210	COG3279	Response regulator of the LytR AlgR family
B4067_RS05215	COG1380	Effector of murein hydrolase LrgA
B4067_RS05220	COG1346	cytolysis
B4067_RS05230	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B4067_RS05235	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B4067_RS05240	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B4067_RS05245	COG3326	Membrane
B4067_RS05255	COG1363	Peptidase, m42
B4067_RS05260	COG3507	Belongs to the glycosyl hydrolase 43 family
B4067_RS05265	COG2160	L-arabinose isomerase activity
B4067_RS05270	COG1069	ribulokinase activity
B4067_RS05275	COG0235	Class ii aldolase
B4067_RS05280	COG0647	UMP catabolic process
B4067_RS05285	COG0371	Dehydrogenase
B4067_RS05290	COG1653	transport
B4067_RS05295	COG1175	transmembrane transport
B4067_RS05300	COG0395	ABC-type sugar transport system, permease component
B4067_RS05305	COG3534	alpha-L-arabinofuranosidase
B4067_RS05310	COG1966	Carbon starvation protein
B4067_RS05320	COG0346	lactoylglutathione lyase activity
B4067_RS05325	COG0247	lactate metabolic process
B4067_RS05330	COG0277	FAD linked oxidase domain protein
B4067_RS05335	COG3835	regulator
B4067_RS05345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B4067_RS05355	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B4067_RS05360	COG0072	phenylalanine-tRNA ligase activity
B4067_RS05360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B4067_RS05365	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B4067_RS05370	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
B4067_RS05375	COG1286	toxin biosynthetic process
B4067_RS05380	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B4067_RS05380	COG1796	DNA polymerase
B4067_RS05385	COG1193	negative regulation of DNA recombination
B4067_RS05390	COG3766	membrane
B4067_RS05395	COG0318	PFAM AMP-dependent synthetase and ligase
B4067_RS05400	COG1309	transcriptional regulator
B4067_RS05405	COG1024	Enoyl-CoA hydratase
B4067_RS05410	COG2086	electron transfer activity
B4067_RS05415	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B4067_RS05420	COG3534	alpha-L-arabinofuranosidase
B4067_RS05425	COG3118	belongs to the thioredoxin family
B4067_RS05430	COG0322	excinuclease ABC activity
B4067_RS05435	COG0527	aspartate kinase activity
B4067_RS05440	COG1719	4-vinyl reductase, 4VR
B4067_RS05450	COG2009	succinate dehydrogenase
B4067_RS05455	COG1053	succinate dehydrogenase
B4067_RS05460	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B4067_RS05465	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B4067_RS05475	COG0513	Belongs to the DEAD box helicase family
B4067_RS05480	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B4067_RS05490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4067_RS05495	COG0735	belongs to the Fur family
B4067_RS05500	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
B4067_RS05505	COG4709	membrane
B4067_RS05510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B4067_RS05515	COG1388	LysM domain
B4067_RS05520	COG5521	maltodextrose utilization protein MalA
B4067_RS05525	COG2839	Protein conserved in bacteria
B4067_RS05530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B4067_RS05535	COG0477	Major facilitator Superfamily
B4067_RS05540	COG0768	penicillin binding
B4067_RS05545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B4067_RS05550	COG0573	inorganic phosphate transmembrane transporter activity
B4067_RS05555	COG0581	inorganic phosphate transmembrane transporter activity
B4067_RS05560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B4067_RS05565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B4067_RS05570	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B4067_RS05585	COG0438	transferase activity, transferring glycosyl groups
B4067_RS05595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B4067_RS05605	COG0705	Rhomboid family
B4067_RS05605	COG0457	Tetratricopeptide repeat
B4067_RS05610	COG4483	Protein conserved in bacteria
B4067_RS05615	COG1940	carbohydrate kinase activity
B4067_RS05620	COG1368	sulfuric ester hydrolase activity
B4067_RS05625	COG2866	Carboxypeptidase
B4067_RS05635	COG0011	TIGRFAM Protein of
B4067_RS05645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4067_RS05655	COG1393	Belongs to the ArsC family
B4067_RS05665	COG1366	Belongs to the anti-sigma-factor antagonist family
B4067_RS05670	COG1253	flavin adenine dinucleotide binding
B4067_RS05675	COG0598	Magnesium transport protein CorA
B4067_RS05680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B4067_RS05685	COG1459	type II secretion system
B4067_RS05690	COG4537	Required for transformation and DNA binding
B4067_RS05695	COG4970	Tfp pilus assembly protein FimT
B4067_RS05705	COG4940	Competence protein ComGF
B4067_RS05730	COG0681	Belongs to the peptidase S26 family
B4067_RS05740	COG1396	sequence-specific DNA binding
B4067_RS05755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B4067_RS05760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B4067_RS05765	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B4067_RS05770	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B4067_RS05775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B4067_RS05780	COG0095	Lipoate-protein ligase
B4067_RS05785	COG1321	iron dependent repressor
B4067_RS05790	COG1752	Esterase of the alpha-beta hydrolase superfamily
B4067_RS05800	COG3872	metal-dependent enzyme
B4067_RS05810	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B4067_RS05815	COG0006	proline dipeptidase activity
B4067_RS05820	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B4067_RS05830	COG3854	ATPases associated with a variety of cellular activities
B4067_RS05870	COG0511	ligase activity, forming carbon-carbon bonds
B4067_RS05875	COG0439	Biotin carboxylase
B4067_RS05880	COG1302	Protein conserved in bacteria
B4067_RS05885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B4067_RS05890	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B4067_RS05895	COG1570	exodeoxyribonuclease VII activity
B4067_RS05900	COG1722	exodeoxyribonuclease VII activity
B4067_RS05905	COG0142	geranyltranstransferase activity
B4067_RS05910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B4067_RS05915	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B4067_RS05920	COG1438	arginine binding
B4067_RS05925	COG0497	DNA recombination
B4067_RS05930	COG0750	zinc metalloprotease
B4067_RS05940	COG0745	RESPONSE REGULATOR receiver
B4067_RS05950	COG1902	pentaerythritol trinitrate reductase activity
B4067_RS05965	COG0860	N-Acetylmuramoyl-L-alanine amidase
B4067_RS05970	COG0584	glycerophosphoryl diester phosphodiesterase
B4067_RS05975	COG0183	Belongs to the thiolase family
B4067_RS05980	COG1250	3-hydroxyacyl-CoA dehydrogenase
B4067_RS05985	COG1960	acyl-CoA dehydrogenase activity
B4067_RS05990	COG0372	Belongs to the citrate synthase family
B4067_RS05995	COG2079	MmgE PrpD family protein
B4067_RS06000	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B4067_RS06010	COG3290	protein histidine kinase activity
B4067_RS06010	COG3829	transcription factor binding
B4067_RS06015	COG0280	phosphate acetyltransferase
B4067_RS06020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B4067_RS06025	COG3426	butyrate kinase activity
B4067_RS06030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B4067_RS06035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B4067_RS06040	COG0022	dehydrogenase e1 component
B4067_RS06045	COG0508	dehydrogenase complex catalyzes the overall conversion of
B4067_RS06050	COG0789	Transcriptional regulator
B4067_RS06050	COG4978	Transcriptional regulator
B4067_RS06055	COG2814	Major facilitator Superfamily
B4067_RS06060	COG1597	lipid kinase activity
B4067_RS06070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B4067_RS06075	COG0765	amino acid transport
B4067_RS06080	COG1126	abc transporter atp-binding protein
B4067_RS06085	COG4129	membrane
B4067_RS06090	COG1376	ErfK ybiS ycfS ynhG family protein
B4067_RS06100	COG0346	lactoylglutathione lyase activity
B4067_RS06105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B4067_RS06110	COG2195	Cleaves the N-terminal amino acid of tripeptides
B4067_RS06115	COG1607	acyl-coa hydrolase
B4067_RS06120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B4067_RS06125	COG2610	gluconate transmembrane transporter activity
B4067_RS06135	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B4067_RS06135	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B4067_RS06140	COG1012	belongs to the aldehyde dehydrogenase family
B4067_RS06160	COG2188	Transcriptional regulator
B4067_RS06165	COG2188	Transcriptional regulator
B4067_RS06170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B4067_RS06175	COG0556	nucleotide-excision repair
B4067_RS06180	COG4897	Protein conserved in bacteria
B4067_RS06185	COG0574	Belongs to the PEP-utilizing enzyme family
B4067_RS06185	COG3848	Pyruvate phosphate dikinase
B4067_RS06190	COG1309	transcriptional regulator
B4067_RS06195	COG2814	Major facilitator Superfamily
B4067_RS06200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B4067_RS06210	COG0793	Belongs to the peptidase S41A family
B4067_RS06210	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS06215	COG2177	Part of the ABC transporter FtsEX involved in
B4067_RS06220	COG2884	Cell division ATP-binding protein ftsE
B4067_RS06225	COG2010	Cytochrome c
B4067_RS06230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4067_RS06235	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B4067_RS06240	COG0653	protein targeting
B4067_RS06245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B4067_RS06260	COG1516	flagellar protein fliS
B4067_RS06265	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B4067_RS06270	COG1334	flagellar protein FlaG
B4067_RS06280	COG2070	2-Nitropropane dioxygenase
B4067_RS06285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B4067_RS06305	COG1595	DNA-templated transcription, initiation
B4067_RS06310	COG0667	Aldo Keto reductase
B4067_RS06315	COG2851	Citrate transporter
B4067_RS06320	COG0583	DNA-binding transcription factor activity
B4067_RS06325	COG2828	Protein conserved in bacteria
B4067_RS06335	COG5566	PFAM Mor transcription activator
B4067_RS06340	COG0596	Alpha beta hydrolase
B4067_RS06345	COG4991	sh3 domain protein
B4067_RS06350	COG4991	sh3 domain protein
B4067_RS06355	COG0346	lactoylglutathione lyase activity
B4067_RS06365	COG5577	PFAM Coat F domain
B4067_RS06370	COG1063	alcohol dehydrogenase
B4067_RS06380	COG5577	PFAM Coat F domain
B4067_RS06385	COG0789	Transcriptional regulator
B4067_RS06395	COG0693	protein deglycase activity
B4067_RS06400	COG1621	beta-fructofuranosidase activity
B4067_RS06405	COG3716	PTS system mannose fructose sorbose family IID component
B4067_RS06410	COG3715	PTS system
B4067_RS06415	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4067_RS06420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B4067_RS06425	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B4067_RS06425	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B4067_RS06430	COG1113	amino acid transport
B4067_RS06435	COG1280	lysine exporter protein (LysE YggA)
B4067_RS06440	COG1378	Sugar-specific transcriptional regulator TrmB
B4067_RS06445	COG1595	DNA-templated transcription, initiation
B4067_RS06455	COG2755	lipolytic protein G-D-S-L family
B4067_RS06455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B4067_RS06465	COG2124	cytochrome p450
B4067_RS06465	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B4067_RS06470	COG1309	transcriptional regulator
B4067_RS06475	COG2226	methyltransferase
B4067_RS06490	COG2116	formate transmembrane transporter activity
B4067_RS06495	COG5609	conserved protein (DUF2294)
B4067_RS06500	COG3383	formate dehydrogenase (NAD+) activity
B4067_RS06505	COG2427	Protein of unknown function (DUF1641)
B4067_RS06515	COG0626	cystathionine gamma-synthase activity
B4067_RS06520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B4067_RS06525	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B4067_RS06530	COG2226	methyltransferase
B4067_RS06545	COG0768	penicillin binding
B4067_RS06550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B4067_RS06555	COG0572	uridine kinase
B4067_RS06560	COG0826	peptidase U32
B4067_RS06565	COG0826	peptidase U32
B4067_RS06570	COG4122	O-methyltransferase activity
B4067_RS06575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B4067_RS06580	COG3906	Belongs to the UPF0473 family
B4067_RS06585	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B4067_RS06590	COG4472	Bacterial protein of unknown function (DUF965)
B4067_RS06595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B4067_RS06600	COG0628	permease
B4067_RS06605	COG1126	abc transporter atp-binding protein
B4067_RS06610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B4067_RS06615	COG0765	amino acid transport
B4067_RS06620	COG0765	amino acid transport
B4067_RS06625	COG2217	Heavy metal translocating P-type atpase
B4067_RS06630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B4067_RS06635	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B4067_RS06640	COG2860	membrane
B4067_RS06645	COG3973	AAA domain
B4067_RS06650	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B4067_RS06655	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B4067_RS06660	COG0025	NhaP-type Na H and K H
B4067_RS06670	COG0656	L-ascorbic acid biosynthetic process
B4067_RS06675	COG4149	molybdate abc transporter
B4067_RS06680	COG0725	ABC transporter, periplasmic molybdate-binding protein
B4067_RS06685	COG1910	domain protein
B4067_RS06690	COG1368	sulfuric ester hydrolase activity
B4067_RS06695	COG1988	membrane-bound metal-dependent
B4067_RS06705	COG0531	amino acid
B4067_RS06715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4067_RS06720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4067_RS06725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4067_RS06730	COG1120	ATPase activity
B4067_RS06735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B4067_RS06740	COG1136	(ABC) transporter
B4067_RS06745	COG0577	efflux transmembrane transporter activity
B4067_RS06755	COG2140	Oxalate decarboxylase
B4067_RS06765	COG1191	sigma factor activity
B4067_RS06775	COG0745	RESPONSE REGULATOR receiver
B4067_RS06780	COG2205	protein histidine kinase activity
B4067_RS06785	COG3386	PFAM SMP-30 Gluconolaconase
B4067_RS06790	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS06800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4067_RS06805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4067_RS06810	COG1120	ATPase activity
B4067_RS06815	COG2096	Adenosyltransferase
B4067_RS06820	COG2814	Major facilitator Superfamily
B4067_RS06825	COG4758	membrane
B4067_RS06830	COG1842	Phage shock protein A
B4067_RS06835	COG3595	metallopeptidase activity
B4067_RS06840	COG4758	membrane
B4067_RS06845	COG4585	Histidine kinase
B4067_RS06850	COG2197	response regulator
B4067_RS06860	COG0814	amino acid
B4067_RS06865	COG0697	spore germination
B4067_RS06875	COG0114	fumarate hydratase activity
B4067_RS06880	COG1309	transcriptional regulator
B4067_RS06890	COG2205	protein histidine kinase activity
B4067_RS06890	COG2770	Histidine kinase
B4067_RS06895	COG0745	RESPONSE REGULATOR receiver
B4067_RS06900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B4067_RS06905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B4067_RS06910	COG0783	Belongs to the Dps family
B4067_RS06915	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS06930	COG1120	ATPase activity
B4067_RS06940	COG1970	mechanosensitive ion channel activity
B4067_RS06945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B4067_RS06950	COG0457	Tetratricopeptide repeat
B4067_RS06955	COG4786	Flagellar basal body rod
B4067_RS06960	COG4786	Flagellar basal body rod
B4067_RS06965	COG1077	Cell shape determining protein MreB Mrl
B4067_RS06970	COG1609	Transcriptional regulator
B4067_RS06975	COG1846	Transcriptional regulator
B4067_RS06980	COG2814	Major facilitator Superfamily
B4067_RS06985	COG3420	alginic acid biosynthetic process
B4067_RS06990	COG1953	Uracil, thiamine, allantoin
B4067_RS06995	COG0477	Major facilitator Superfamily
B4067_RS07000	COG1335	isochorismatase
B4067_RS07010	COG0004	ammonium transporteR
B4067_RS07015	COG0347	Belongs to the P(II) protein family
B4067_RS07020	COG0671	phosphoesterase, PA-phosphatase related
B4067_RS07030	COG0739	heme binding
B4067_RS07035	COG1247	-acetyltransferase
B4067_RS07055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B4067_RS07060	COG0789	Transcriptional regulator
B4067_RS07075	COG0457	Tetratricopeptide repeat
B4067_RS07105	COG1077	Cell shape determining protein MreB Mrl
B4067_RS07115	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B4067_RS07120	COG0850	regulation of cytokinetic process
B4067_RS07125	COG2894	cell division
B4067_RS07130	COG0739	heme binding
B4067_RS07135	COG1994	Peptidase M50
B4067_RS07140	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B4067_RS07145	COG2868	ribosomal protein
B4067_RS07150	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B4067_RS07160	COG3290	protein histidine kinase activity
B4067_RS07165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B4067_RS07170	COG4492	Belongs to the UPF0735 family
B4067_RS07175	COG0077	Prephenate dehydratase
B4067_RS07180	COG1827	regulation of RNA biosynthetic process
B4067_RS07185	COG1104	cysteine desulfurase activity
B4067_RS07190	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B4067_RS07195	COG0157	Belongs to the NadC ModD family
B4067_RS07200	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B4067_RS07205	COG1388	LysM domain
B4067_RS07215	COG0217	transcriptional regulatory protein
B4067_RS07220	COG1115	amino acid carrier protein
B4067_RS07240	COG2112	serine threonine protein kinase
B4067_RS07245	COG0673	inositol 2-dehydrogenase activity
B4067_RS07250	COG2814	Major facilitator Superfamily
B4067_RS07260	COG0632	four-way junction helicase activity
B4067_RS07265	COG2255	four-way junction helicase activity
B4067_RS07275	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B4067_RS07280	COG0343	queuine tRNA-ribosyltransferase activity
B4067_RS07285	COG1862	Preprotein translocase
B4067_RS07295	COG2323	membrane
B4067_RS07300	COG2244	polysaccharide biosynthetic process
B4067_RS07310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B4067_RS07310	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B4067_RS07315	COG0490	domain, Protein
B4067_RS07320	COG5416	Lipopolysaccharide assembly protein A domain
B4067_RS07325	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B4067_RS07325	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B4067_RS07330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B4067_RS07335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B4067_RS07340	COG1490	D-aminoacyl-tRNA deacylase activity
B4067_RS07345	COG4991	sh3 domain protein
B4067_RS07345	COG3103	Sh3 type 3 domain protein
B4067_RS07345	COG0860	N-Acetylmuramoyl-L-alanine amidase
B4067_RS07355	COG0124	histidyl-tRNA synthetase
B4067_RS07360	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B4067_RS07370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B4067_RS07375	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B4067_RS07380	COG1959	2 iron, 2 sulfur cluster binding
B4067_RS07385	COG1104	cysteine desulfurase activity
B4067_RS07390	COG0482	sulfurtransferase activity
B4067_RS07395	COG0457	Tetratricopeptide repeat
B4067_RS07400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B4067_RS07405	COG3881	PFAM PRC-barrel domain
B4067_RS07425	COG0583	DNA-binding transcription factor activity
B4067_RS07430	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B4067_RS07435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B4067_RS07440	COG2211	Major facilitator Superfamily
B4067_RS07450	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
B4067_RS07450	COG0028	Belongs to the TPP enzyme family
B4067_RS07495	COG1113	amino acid transport
B4067_RS07510	COG2602	Beta-lactamase
B4067_RS07515	COG2124	cytochrome p450
B4067_RS07530	COG2322	membrane
B4067_RS07545	COG1619	proteins homologs of microcin C7 resistance protein MccF
B4067_RS07550	COG3239	Fatty acid desaturase
B4067_RS07555	COG4585	Histidine kinase
B4067_RS07560	COG2197	response regulator
B4067_RS07565	COG1388	LysM domain
B4067_RS07565	COG3584	3D domain protein
B4067_RS07570	COG0514	ATP-dependent DNA helicase (RecQ)
B4067_RS07580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B4067_RS07585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B4067_RS07600	COG0071	Belongs to the small heat shock protein (HSP20) family
B4067_RS07625	COG1012	belongs to the aldehyde dehydrogenase family
B4067_RS07630	COG1657	PFAM Prenyltransferase squalene oxidase
B4067_RS07635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B4067_RS07640	COG0733	neurotransmitter:sodium symporter activity
B4067_RS07645	COG0385	Bile acid
B4067_RS07650	COG0508	dehydrogenase complex catalyzes the overall conversion of
B4067_RS07655	COG0567	Dehydrogenase, E1 component
B4067_RS07660	COG4548	von Willebrand factor, type A
B4067_RS07665	COG0714	Associated with various cellular activities
B4067_RS07670	COG2032	superoxide dismutase activity
B4067_RS07675	COG0791	NLP P60 protein
B4067_RS07675	COG1388	LysM domain
B4067_RS07680	COG1819	glycosyl
B4067_RS07685	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B4067_RS07690	COG0534	Mate efflux family protein
B4067_RS07695	COG1366	Belongs to the anti-sigma-factor antagonist family
B4067_RS07700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B4067_RS07705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B4067_RS07715	COG2962	Rard protein
B4067_RS07730	COG2610	gluconate transmembrane transporter activity
B4067_RS07735	COG1942	4-Oxalocrotonate Tautomerase
B4067_RS07740	COG1733	regulation of RNA biosynthetic process
B4067_RS07745	COG0778	Nitroreductase
B4067_RS07750	COG0400	carboxylic ester hydrolase activity
B4067_RS07755	COG0346	lactoylglutathione lyase activity
B4067_RS07765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B4067_RS07770	COG0793	Belongs to the peptidase S41A family
B4067_RS07770	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS07775	COG2226	methyltransferase
B4067_RS07785	COG1876	peptidase activity
B4067_RS07790	COG0813	purine-nucleoside phosphorylase activity
B4067_RS07805	COG0671	phosphoesterase, PA-phosphatase related
B4067_RS07830	COG4479	Belongs to the UPF0346 family
B4067_RS07840	COG1509	lysine 2,3-aminomutase activity
B4067_RS07860	COG3118	belongs to the thioredoxin family
B4067_RS07865	COG4980	gas vesicle protein
B4067_RS07870	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
B4067_RS07875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B4067_RS07880	COG1674	ftsk spoiiie
B4067_RS07885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B4067_RS07890	COG4848	Belongs to the UPF0354 family
B4067_RS07895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4067_RS07905	COG1363	Peptidase, m42
B4067_RS07910	COG5584	Small secreted protein
B4067_RS07915	COG0281	malic enzyme
B4067_RS07920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4067_RS07925	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B4067_RS07935	COG0510	thiamine kinase activity
B4067_RS07940	COG1523	belongs to the glycosyl hydrolase 13 family
B4067_RS07945	COG1597	lipid kinase activity
B4067_RS07955	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B4067_RS07960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B4067_RS07965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B4067_RS07970	COG2252	PERMEase
B4067_RS07975	COG4473	ABC transporter
B4067_RS07980	COG1131	(ABC) transporter
B4067_RS07985	COG1349	DNA-binding transcription factor activity
B4067_RS07990	COG1187	pseudouridine synthase activity
B4067_RS07995	COG2244	polysaccharide biosynthetic process
B4067_RS08000	COG2081	HI0933 family
B4067_RS08005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B4067_RS08015	COG5578	integral membrane protein
B4067_RS08020	COG0673	inositol 2-dehydrogenase activity
B4067_RS08025	COG1653	transport
B4067_RS08030	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B4067_RS08035	COG4209	transmembrane transport
B4067_RS08040	COG2207	Transcriptional regulator
B4067_RS08045	COG1653	transport
B4067_RS08050	COG0395	ABC-type sugar transport system, permease component
B4067_RS08055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B4067_RS08060	COG2124	cytochrome p450
B4067_RS08065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B4067_RS08075	COG0156	8-amino-7-oxononanoate synthase activity
B4067_RS08080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B4067_RS08085	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
B4067_RS08090	COG1073	alpha beta
B4067_RS08095	COG1609	Transcriptional regulator
B4067_RS08100	COG1653	transport
B4067_RS08105	COG1175	transmembrane transport
B4067_RS08110	COG0395	ABC-type sugar transport system, permease component
B4067_RS08115	COG1486	melibiose metabolic process
B4067_RS08120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B4067_RS08125	COG0495	leucyl-tRNA aminoacylation
B4067_RS08135	COG2202	Pas domain
B4067_RS08135	COG1366	Belongs to the anti-sigma-factor antagonist family
B4067_RS08140	COG2814	Major facilitator Superfamily
B4067_RS08145	COG2433	Pfam Transposase IS66
B4067_RS08150	COG0577	efflux transmembrane transporter activity
B4067_RS08155	COG1136	(ABC) transporter
B4067_RS08160	COG2205	protein histidine kinase activity
B4067_RS08165	COG0745	RESPONSE REGULATOR receiver
B4067_RS08170	COG0577	efflux transmembrane transporter activity
B4067_RS08175	COG1136	(ABC) transporter
B4067_RS08190	COG1131	(ABC) transporter
B4067_RS08195	COG1725	Transcriptional regulator
B4067_RS08210	COG1242	4 iron, 4 sulfur cluster binding
B4067_RS08215	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B4067_RS08225	COG2267	carboxylic ester hydrolase activity
B4067_RS08230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B4067_RS08235	COG1113	amino acid transport
B4067_RS08240	COG0367	asparagine synthase
B4067_RS08245	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B4067_RS08250	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B4067_RS08260	COG1506	peptidase
B4067_RS08265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B4067_RS08270	COG1116	anion transmembrane transporter activity
B4067_RS08275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B4067_RS08280	COG0494	nUDIX hydrolase
B4067_RS08285	COG4824	toxin secretion phage lysis holin
B4067_RS08290	COG0783	Belongs to the Dps family
B4067_RS08305	COG1854	S-ribosylhomocysteine lyase activity
B4067_RS08310	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B4067_RS08315	COG0288	reversible hydration of carbon dioxide
B4067_RS08320	COG0254	rRNA binding
B4067_RS08325	COG1271	oxidase subunit
B4067_RS08330	COG1294	oxidase, subunit
B4067_RS08360	COG1510	regulation of RNA biosynthetic process
B4067_RS08365	COG1125	glycine betaine transport
B4067_RS08365	COG0517	IMP dehydrogenase activity
B4067_RS08370	COG1174	glycine betaine transport
B4067_RS08375	COG1732	Glycine betaine
B4067_RS08380	COG1174	glycine betaine transport
B4067_RS08390	COG1733	regulation of RNA biosynthetic process
B4067_RS08395	COG1396	sequence-specific DNA binding
B4067_RS08400	COG1396	sequence-specific DNA binding
B4067_RS08405	COG1476	TRANSCRIPTIONal
B4067_RS08410	COG0596	Alpha beta hydrolase
B4067_RS08415	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B4067_RS08420	COG1647	Serine aminopeptidase, S33
B4067_RS08425	COG0557	exoribonuclease II activity
B4067_RS08430	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B4067_RS08440	COG1309	transcriptional regulator
B4067_RS08445	COG2076	Multidrug Resistance protein
B4067_RS08455	COG1289	transmembrane transporter activity
B4067_RS08460	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B4067_RS08465	COG0673	inositol 2-dehydrogenase activity
B4067_RS08470	COG1937	Protein conserved in bacteria
B4067_RS08475	COG2608	mercury ion transmembrane transporter activity
B4067_RS08480	COG2217	Heavy metal translocating P-type atpase
B4067_RS08485	COG1575	Belongs to the MenA family. Type 1 subfamily
B4067_RS08500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B4067_RS08505	COG1696	Membrane protein involved in D-alanine export
B4067_RS08510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B4067_RS08515	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
B4067_RS08520	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
B4067_RS08525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B4067_RS08530	COG1486	melibiose metabolic process
B4067_RS08535	COG1447	Phosphotransferase system cellobiose-specific component IIA
B4067_RS08540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B4067_RS08545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B4067_RS08550	COG3711	transcriptional antiterminator
B4067_RS08550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B4067_RS08565	COG0753	catalase activity
B4067_RS08570	COG2814	Major facilitator Superfamily
B4067_RS08580	COG1131	(ABC) transporter
B4067_RS08600	COG1595	DNA-templated transcription, initiation
B4067_RS08605	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B4067_RS08610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B4067_RS08615	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B4067_RS08620	COG4988	ABC transporter
B4067_RS08625	COG1294	oxidase, subunit
B4067_RS08630	COG1271	oxidase subunit
B4067_RS08635	COG3493	citrate carrier protein
B4067_RS08640	COG0501	Belongs to the peptidase M48B family
B4067_RS08650	COG0726	polysaccharide deacetylase
B4067_RS08655	COG3842	ATPase activity
B4067_RS08660	COG2508	Transcriptional regulator
B4067_RS08665	COG1012	belongs to the aldehyde dehydrogenase family
B4067_RS08670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4067_RS08680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B4067_RS08690	COG4585	Histidine kinase
B4067_RS08695	COG2197	response regulator
B4067_RS08700	COG2195	Cleaves the N-terminal amino acid of tripeptides
B4067_RS08715	COG4894	glucomannan catabolic process
B4067_RS08720	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B4067_RS08725	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B4067_RS08735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B4067_RS08740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B4067_RS08745	COG2610	gluconate transmembrane transporter activity
B4067_RS08755	COG0500	methyltransferase
B4067_RS08760	COG0589	response to stress
B4067_RS08765	COG2723	6-phospho-beta-galactosidase activity
B4067_RS08770	COG2190	(PTS) system
B4067_RS08770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4067_RS08770	COG1263	PTS System
B4067_RS08780	COG5444	nuclease activity
B4067_RS08800	COG0494	nUDIX hydrolase
B4067_RS08805	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
B4067_RS08810	COG3507	Belongs to the glycosyl hydrolase 43 family
B4067_RS08815	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B4067_RS08820	COG1228	amidohydrolase
B4067_RS08825	COG0010	Belongs to the arginase family
B4067_RS08830	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B4067_RS08835	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B4067_RS08840	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B4067_RS08845	COG2390	Transcriptional regulator
B4067_RS08855	COG3192	ethanolamine utilization protein
B4067_RS08860	COG2079	MmgE PrpD family protein
B4067_RS08865	COG1473	amidohydrolase
B4067_RS08870	COG1126	abc transporter atp-binding protein
B4067_RS08875	COG0765	amino acid transport
B4067_RS08880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B4067_RS08885	COG0456	acetyltransferase
B4067_RS08890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B4067_RS08895	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
B4067_RS08900	COG0561	phosphatase activity
B4067_RS08930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4067_RS08935	COG5294	Protein conserved in bacteria
B4067_RS08940	COG0577	efflux transmembrane transporter activity
B4067_RS08945	COG1136	(ABC) transporter
B4067_RS08955	COG0745	RESPONSE REGULATOR receiver
B4067_RS08960	COG0191	fructose-bisphosphate aldolase activity
B4067_RS08965	COG1082	Xylose isomerase domain protein TIM barrel
B4067_RS08970	COG1082	Xylose isomerase domain protein TIM barrel
B4067_RS08975	COG0673	inositol 2-dehydrogenase activity
B4067_RS08980	COG2814	Major facilitator Superfamily
B4067_RS08985	COG1082	Xylose isomerase domain protein TIM barrel
B4067_RS08990	COG3962	Belongs to the TPP enzyme family
B4067_RS08995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B4067_RS09000	COG3718	enzyme involved in inositol metabolism
B4067_RS09005	COG1012	belongs to the aldehyde dehydrogenase family
B4067_RS09010	COG1349	DNA-binding transcription factor activity
B4067_RS09015	COG0667	Aldo Keto reductase
B4067_RS09030	COG2814	Major facilitator Superfamily
B4067_RS09035	COG0326	Molecular chaperone. Has ATPase activity
B4067_RS09045	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS09050	COG1309	transcriptional regulator
B4067_RS09055	COG1012	belongs to the aldehyde dehydrogenase family
B4067_RS09065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B4067_RS09075	COG1714	RDD family
B4067_RS09080	COG2311	Membrane
B4067_RS09085	COG1917	Cupin 2, conserved barrel domain protein
B4067_RS09090	COG1309	transcriptional regulator
B4067_RS09095	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS09100	COG0569	domain protein
B4067_RS09105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B4067_RS09110	COG4682	membrane
B4067_RS09115	COG1705	Flagellar rod assembly protein muramidase FlgJ
B4067_RS09120	COG0477	Major facilitator Superfamily
B4067_RS09125	COG5553	Cysteine dioxygenase type I
B4067_RS09135	COG1968	undecaprenyl-diphosphatase activity
B4067_RS09140	COG0628	permease
B4067_RS09145	COG0673	inositol 2-dehydrogenase activity
B4067_RS09150	COG4806	L-rhamnose isomerase
B4067_RS09155	COG3254	rhamnose metabolic process
B4067_RS09160	COG1070	Carbohydrate kinase
B4067_RS09165	COG1349	DNA-binding transcription factor activity
B4067_RS09170	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS09170	COG3347	Dehydrogenase
B4067_RS09175	COG0840	transmembrane signaling receptor activity
B4067_RS09180	COG0840	transmembrane signaling receptor activity
B4067_RS09185	COG0840	transmembrane signaling receptor activity
B4067_RS09190	COG0840	transmembrane signaling receptor activity
B4067_RS09205	COG0432	Pfam Uncharacterised protein family UPF0047
B4067_RS09210	COG0366	Alpha amylase catalytic
B4067_RS09215	COG1253	flavin adenine dinucleotide binding
B4067_RS09220	COG2738	Putative neutral zinc metallopeptidase
B4067_RS09235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B4067_RS09250	COG0166	Belongs to the GPI family
B4067_RS09255	COG1979	alcohol dehydrogenase
B4067_RS09260	COG1979	alcohol dehydrogenase
B4067_RS09265	COG2155	Conserved Protein
B4067_RS09270	COG1098	S1 RNA binding domain
B4067_RS09275	COG0436	Aminotransferase
B4067_RS09280	COG1522	sequence-specific DNA binding
B4067_RS09285	COG2267	carboxylic ester hydrolase activity
B4067_RS09290	COG0493	'glutamate synthase
B4067_RS09295	COG0070	glutamate synthase
B4067_RS09295	COG0067	glutamate synthase
B4067_RS09295	COG0069	glutamate synthase activity
B4067_RS09300	COG0583	DNA-binding transcription factor activity
B4067_RS09305	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B4067_RS09310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B4067_RS09320	COG0300	oxidoreductase activity
B4067_RS09325	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
B4067_RS09335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4067_RS09340	COG2814	Major facilitator Superfamily
B4067_RS09345	COG1070	Carbohydrate kinase
B4067_RS09350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B4067_RS09355	COG0243	molybdopterin cofactor binding
B4067_RS09365	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B4067_RS09370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B4067_RS09375	COG1396	sequence-specific DNA binding
B4067_RS09380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B4067_RS09385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B4067_RS09390	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B4067_RS09395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B4067_RS09400	COG0512	Glutamine amidotransferase of anthranilate synthase
B4067_RS09405	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B4067_RS09410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B4067_RS09415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B4067_RS09420	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B4067_RS09425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B4067_RS09430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B4067_RS09435	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B4067_RS09440	COG0037	tRNA processing
B4067_RS09445	COG0515	serine threonine protein kinase
B4067_RS09450	COG2304	oxidoreductase activity
B4067_RS09455	COG2208	phosphoserine phosphatase activity
B4067_RS09470	COG1098	S1 RNA binding domain
B4067_RS09475	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B4067_RS09490	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B4067_RS09495	COG3956	TIGRFAM MazG family protein
B4067_RS09500	COG2244	polysaccharide biosynthetic process
B4067_RS09505	COG2002	toxin-antitoxin pair type II binding
B4067_RS09510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B4067_RS09520	COG0193	aminoacyl-tRNA hydrolase activity
B4067_RS09525	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B4067_RS09530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B4067_RS09535	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B4067_RS09545	COG2088	sporulation resulting in formation of a cellular spore
B4067_RS09550	COG0251	oxidation-reduction process
B4067_RS09555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B4067_RS09560	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B4067_RS09570	COG4466	Protein conserved in bacteria
B4067_RS09580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B4067_RS09585	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B4067_RS09590	COG3584	3D domain protein
B4067_RS09590	COG3583	domain protein
B4067_RS09595	COG0084	hydrolase, TatD family'
B4067_RS09600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B4067_RS09600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B4067_RS09605	COG2002	toxin-antitoxin pair type II binding
B4067_RS09610	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B4067_RS09615	COG2827	Endonuclease containing a URI domain
B4067_RS09620	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B4067_RS09625	COG4467	Involved in initiation control of chromosome replication
B4067_RS09630	COG1774	PSP1 C-terminal conserved region
B4067_RS09635	COG0470	DNA polymerase III
B4067_RS09640	COG1728	Protein conserved in bacteria
B4067_RS09645	COG3870	Protein conserved in bacteria
B4067_RS09650	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B4067_RS09655	COG1982	Orn Lys Arg decarboxylase major
B4067_RS09660	COG3853	Toxic anion resistance protein (TelA)
B4067_RS09665	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
B4067_RS09685	COG3546	catalase activity
B4067_RS09695	COG0517	IMP dehydrogenase activity
B4067_RS09695	COG0516	GMP reductase activity
B4067_RS09700	COG1686	Belongs to the peptidase S11 family
B4067_RS09705	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
B4067_RS09710	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B4067_RS09715	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B4067_RS09725	COG1428	Deoxynucleoside kinase
B4067_RS09730	COG1428	Deoxynucleoside kinase
B4067_RS09735	COG1388	LysM domain
B4067_RS09735	COG3858	chitin binding
B4067_RS09740	COG1335	isochorismatase
B4067_RS09745	COG0590	tRNA wobble adenosine to inosine editing
B4067_RS09750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B4067_RS09755	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B4067_RS09760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B4067_RS09810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B4067_RS09820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4067_RS09835	COG2356	endonuclease I
B4067_RS09845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B4067_RS09850	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B4067_RS09855	COG2433	Pfam Transposase IS66
B4067_RS09865	COG1196	nuclear chromosome segregation
B4067_RS09865	COG0739	heme binding
B4067_RS09865	COG0741	lytic transglycosylase activity
B4067_RS09890	COG0582	viral genome integration into host DNA
B4067_RS09985	COG4373	Mu-like prophage FluMu protein gp28
B4067_RS10020	COG0776	regulation of translation
B4067_RS10075	COG0210	DNA helicase
B4067_RS10115	COG0739	heme binding
B4067_RS10135	COG1674	ftsk spoiiie
B4067_RS10180	COG0582	viral genome integration into host DNA
B4067_RS10195	COG3655	Transcriptional regulator
B4067_RS10230	COG3645	SOS response
B4067_RS10230	COG3646	Phage regulatory protein
B4067_RS10290	COG1793	dna ligase
B4067_RS10295	COG2135	peptidase activity
B4067_RS10350	COG5444	nuclease activity
B4067_RS10355	COG0457	Tetratricopeptide repeat
B4067_RS10365	COG0640	Transcriptional regulator
B4067_RS10370	COG0346	lactoylglutathione lyase activity
B4067_RS10375	COG0798	PFAM Bile acid sodium symporter
B4067_RS10380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B4067_RS10385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B4067_RS10390	COG1509	lysine 2,3-aminomutase activity
B4067_RS10395	COG0456	acetyltransferase
B4067_RS10400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B4067_RS10405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B4067_RS10410	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B4067_RS10415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B4067_RS10430	COG0456	acetyltransferase
B4067_RS10435	COG0463	Glycosyl transferase, family 2
B4067_RS10450	COG4641	Protein conserved in bacteria
B4067_RS10455	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
B4067_RS10460	COG1086	Polysaccharide biosynthesis protein
B4067_RS10470	COG3331	DNA recombination
B4067_RS10515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B4067_RS10530	COG0457	Tetratricopeptide repeat
B4067_RS10550	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4067_RS10550	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS10565	COG0697	spore germination
B4067_RS10620	COG2755	lipolytic protein G-D-S-L family
B4067_RS10620	COG3401	FG-GAP repeat protein
B4067_RS10625	COG0513	Belongs to the DEAD box helicase family
B4067_RS10630	COG2270	Major facilitator Superfamily
B4067_RS10645	COG2273	Hydrolase Family 16
B4067_RS10650	COG2851	Citrate transporter
B4067_RS10655	COG0753	catalase activity
B4067_RS10655	COG0693	protein deglycase activity
B4067_RS10670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B4067_RS10675	COG3328	transposase activity
B4067_RS10680	COG0351	phosphomethylpyrimidine kinase
B4067_RS10685	COG1695	Transcriptional regulator
B4067_RS10700	COG1216	Glycosyl transferase, family 2
B4067_RS10705	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B4067_RS10710	COG1012	belongs to the aldehyde dehydrogenase family
B4067_RS10720	COG2233	PERMEase
B4067_RS10725	COG2363	Small membrane protein
B4067_RS10740	COG0463	Glycosyl transferase, family 2
B4067_RS10745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B4067_RS10750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B4067_RS10755	COG0456	acetyltransferase
B4067_RS10760	COG2089	acid synthase
B4067_RS10765	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
B4067_RS10770	COG3980	spore coat polysaccharide biosynthesis protein
B4067_RS10775	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B4067_RS10780	COG1088	dTDP-glucose 4,6-dehydratase activity
B4067_RS10785	COG1091	dTDP-4-dehydrorhamnose reductase activity
B4067_RS10790	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
B4067_RS10805	COG1012	belongs to the aldehyde dehydrogenase family
B4067_RS10810	COG4187	Peptidase family M20/M25/M40
B4067_RS10815	COG0833	amino acid
B4067_RS10820	COG2814	Major facilitator Superfamily
B4067_RS10825	COG0077	Prephenate dehydratase
B4067_RS10835	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS10840	COG0151	Belongs to the GarS family
B4067_RS10845	COG2814	Major facilitator Superfamily
B4067_RS10850	COG0436	Aminotransferase
B4067_RS10855	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS10860	COG3253	May function as heme-dependent peroxidase
B4067_RS10865	COG0280	phosphate acetyltransferase
B4067_RS10870	COG0583	DNA-binding transcription factor activity
B4067_RS10875	COG0095	Lipoate-protein ligase
B4067_RS10880	COG0697	spore germination
B4067_RS10890	COG4844	belongs to the
B4067_RS10895	COG1078	dGTPase activity
B4067_RS10900	COG3465	dGTPase activity
B4067_RS10905	COG1959	2 iron, 2 sulfur cluster binding
B4067_RS10910	COG0477	Major facilitator Superfamily
B4067_RS10925	COG1846	Transcriptional regulator
B4067_RS10930	COG1942	4-Oxalocrotonate Tautomerase
B4067_RS10935	COG1994	Peptidase M50
B4067_RS10945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B4067_RS10950	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B4067_RS10955	COG0010	Belongs to the arginase family
B4067_RS10970	COG0457	Tetratricopeptide repeat
B4067_RS10980	COG3391	amine dehydrogenase activity
B4067_RS10985	COG3391	amine dehydrogenase activity
B4067_RS10995	COG0612	Peptidase, M16
B4067_RS11000	COG0612	Peptidase, M16
B4067_RS11005	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B4067_RS11010	COG1131	(ABC) transporter
B4067_RS11020	COG0535	radical SAM domain protein
B4067_RS11030	COG4506	Protein conserved in bacteria
B4067_RS11035	COG0018	arginyl-trna synthetase
B4067_RS11040	COG2223	nitrite transmembrane transporter activity
B4067_RS11045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B4067_RS11055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B4067_RS11060	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B4067_RS11065	COG1140	nitrate reductase beta subunit
B4067_RS11070	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B4067_RS11075	COG2181	nitrate reductase activity
B4067_RS11080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B4067_RS11085	COG1132	(ABC) transporter
B4067_RS11090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B4067_RS11100	COG4294	response to UV
B4067_RS11105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B4067_RS11110	COG2181	nitrate reductase activity
B4067_RS11110	COG0247	lactate metabolic process
B4067_RS11115	COG1960	acyl-CoA dehydrogenase activity
B4067_RS11120	COG3343	RNA polymerase activity
B4067_RS11125	COG0504	CTP synthase activity
B4067_RS11145	COG2137	regulation of response to DNA damage stimulus
B4067_RS11160	COG2814	Major facilitator Superfamily
B4067_RS11180	COG5484	DNA packaging
B4067_RS11185	COG1783	phage Terminase large subunit
B4067_RS11190	COG5518	Phage portal protein
B4067_RS11195	COG2369	cell adhesion
B4067_RS11205	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B4067_RS11210	COG4653	Phage capsid family
B4067_RS11270	COG3953	SLT domain
B4067_RS11270	COG5280	Phage tail tape measure protein TP901
B4067_RS11275	COG1652	LysM domain
B4067_RS11280	COG4193	domain, Protein
B4067_RS11290	COG3628	GPW Gp25 family protein
B4067_RS11295	COG3299	homolog of phage Mu protein gp47
B4067_RS11300	COG3778	Protein conserved in bacteria
B4067_RS11330	COG4824	toxin secretion phage lysis holin
B4067_RS11335	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS11335	COG1388	LysM domain
B4067_RS11335	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4067_RS11350	COG2340	Cysteine-rich secretory protein family
B4067_RS11355	COG0768	penicillin binding
B4067_RS11360	COG4191	Histidine kinase
B4067_RS11365	COG0436	Aminotransferase
B4067_RS11375	COG0835	chemotaxis
B4067_RS11375	COG0784	Response regulator, receiver
B4067_RS11385	COG2814	Major facilitator Superfamily
B4067_RS11390	COG1376	ErfK ybiS ycfS ynhG family protein
B4067_RS11395	COG1408	metallophosphoesterase
B4067_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS11405	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS11415	COG2200	EAL domain
B4067_RS11425	COG4703	Protein of unknown function (DUF1797)
B4067_RS11430	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
B4067_RS11440	COG0517	IMP dehydrogenase activity
B4067_RS11445	COG0583	DNA-binding transcription factor activity
B4067_RS11450	COG0716	FMN binding
B4067_RS11460	COG0716	FMN binding
B4067_RS11465	COG2171	N-acyltransferase activity
B4067_RS11470	COG1473	amidohydrolase
B4067_RS11480	COG0668	transmembrane transport
B4067_RS11485	COG0450	alkyl hydroperoxide reductase
B4067_RS11490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4067_RS11500	COG0697	spore germination
B4067_RS11505	COG0583	DNA-binding transcription factor activity
B4067_RS11510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B4067_RS11515	COG1609	Transcriptional regulator
B4067_RS11520	COG2814	Major facilitator Superfamily
B4067_RS11525	COG2390	Transcriptional regulator
B4067_RS11530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B4067_RS11540	COG0126	phosphoglycerate kinase activity
B4067_RS11545	COG0149	triose-phosphate isomerase activity
B4067_RS11550	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
B4067_RS11555	COG0148	phosphopyruvate hydratase activity
B4067_RS11560	COG0456	acetyltransferase
B4067_RS11570	COG3064	Membrane
B4067_RS11580	COG2095	MarC family integral membrane protein
B4067_RS11585	COG1510	regulation of RNA biosynthetic process
B4067_RS11590	COG1125	glycine betaine transport
B4067_RS11590	COG0517	IMP dehydrogenase activity
B4067_RS11595	COG1174	glycine betaine transport
B4067_RS11600	COG1732	Glycine betaine
B4067_RS11605	COG1174	glycine betaine transport
B4067_RS11610	COG0640	Transcriptional regulator
B4067_RS11615	COG5658	integral membrane protein
B4067_RS11640	COG0726	polysaccharide deacetylase
B4067_RS11645	COG2194	sulfuric ester hydrolase activity
B4067_RS11655	COG0489	protein tyrosine kinase activity
B4067_RS11660	COG0860	N-Acetylmuramoyl-L-alanine amidase
B4067_RS11670	COG2226	methyltransferase
B4067_RS11675	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B4067_RS11680	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B4067_RS11685	COG0101	tRNA pseudouridine synthase activity
B4067_RS11690	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B4067_RS11695	COG1122	ATPase activity
B4067_RS11700	COG1122	ATPase activity
B4067_RS11705	COG0203	ribosomal protein L17
B4067_RS11710	COG0202	RNA polymerase activity
B4067_RS11715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B4067_RS11720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B4067_RS11725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B4067_RS11735	COG2163	COG2163 Ribosomal protein L14E L6E L27E
B4067_RS11740	COG0024	Methionine aminopeptidase
B4067_RS11745	COG0563	adenylate kinase activity
B4067_RS11750	COG0201	protein transport
B4067_RS11755	COG0200	Binds to the 23S rRNA
B4067_RS11765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B4067_RS11770	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B4067_RS11775	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B4067_RS11780	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B4067_RS11790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B4067_RS11805	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B4067_RS11815	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B4067_RS11820	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B4067_RS11835	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B4067_RS11845	COG0088	Forms part of the polypeptide exit tunnel
B4067_RS11850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B4067_RS11860	COG0596	Alpha beta hydrolase
B4067_RS11865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B4067_RS11870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B4067_RS11875	COG0049	tRNA binding
B4067_RS11880	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B4067_RS11885	COG1358	cellular component organization or biogenesis
B4067_RS11890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B4067_RS11895	COG0085	RNA polymerase activity
B4067_RS11900	COG2813	Specifically methylates the guanine in position
B4067_RS11910	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B4067_RS11915	COG0081	regulation of translation
B4067_RS11925	COG0250	Participates in transcription elongation, termination and antitermination
B4067_RS11930	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B4067_RS11940	COG1595	DNA-templated transcription, initiation
B4067_RS11945	COG3688	RNA-binding protein containing a PIN domain
B4067_RS11950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B4067_RS11955	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
B4067_RS11960	COG0215	cysteine-tRNA ligase activity
B4067_RS11965	COG1045	serine acetyltransferase
B4067_RS11975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B4067_RS11980	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B4067_RS11985	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B4067_RS11990	COG4956	integral membrane protein (PIN domain superfamily)
B4067_RS11995	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
B4067_RS12000	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B4067_RS12005	COG0542	response to heat
B4067_RS12010	COG3869	Catalyzes the specific phosphorylation of arginine residues in
B4067_RS12015	COG3880	PFAM UvrB UvrC protein
B4067_RS12020	COG4463	regulation of RNA biosynthetic process
B4067_RS12030	COG1846	Transcriptional regulator
B4067_RS12035	COG1380	Effector of murein hydrolase LrgA
B4067_RS12040	COG1346	cytolysis
B4067_RS12050	COG1929	Belongs to the glycerate kinase type-1 family
B4067_RS12055	COG1802	Transcriptional regulator
B4067_RS12060	COG1070	Carbohydrate kinase
B4067_RS12065	COG2610	gluconate transmembrane transporter activity
B4067_RS12070	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B4067_RS12075	COG0450	alkyl hydroperoxide reductase
B4067_RS12080	COG3634	alkyl hydroperoxide reductase activity
B4067_RS12085	COG2723	6-phospho-beta-galactosidase activity
B4067_RS12090	COG2190	(PTS) system
B4067_RS12095	COG2188	Transcriptional regulator
B4067_RS12110	COG1131	(ABC) transporter
B4067_RS12115	COG1994	Peptidase M50
B4067_RS12120	COG0535	radical SAM domain protein
B4067_RS12130	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
B4067_RS12160	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B4067_RS12170	COG1063	alcohol dehydrogenase
B4067_RS12190	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
B4067_RS12195	COG0456	acetyltransferase
B4067_RS12200	COG0457	Tetratricopeptide repeat
B4067_RS12210	COG0010	Belongs to the arginase family
B4067_RS12215	COG0833	amino acid
B4067_RS12220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B4067_RS12225	COG3829	transcription factor binding
B4067_RS12235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B4067_RS12240	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B4067_RS12245	COG4853	Protein conserved in bacteria
B4067_RS12250	COG4863	YycH protein
B4067_RS12255	COG5002	protein histidine kinase activity
B4067_RS12260	COG0745	RESPONSE REGULATOR receiver
B4067_RS12285	COG0346	lactoylglutathione lyase activity
B4067_RS12290	COG0305	Participates in initiation and elongation during chromosome replication
B4067_RS12310	COG3093	addiction module antidote protein HigA
B4067_RS12315	COG2807	transmembrane transport
B4067_RS12320	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B4067_RS12325	COG0359	binds to the 23S rRNA
B4067_RS12330	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
B4067_RS12335	COG4241	membrane
B4067_RS12350	COG1733	regulation of RNA biosynthetic process
B4067_RS12355	COG1227	inorganic diphosphatase activity
B4067_RS12370	COG2271	Major facilitator Superfamily
B4067_RS12385	COG4319	ketosteroid isomerase
B4067_RS12390	COG1357	PFAM Pentapeptide repeats (8 copies)
B4067_RS12395	COG2814	Major facilitator Superfamily
B4067_RS12400	COG0583	DNA-binding transcription factor activity
B4067_RS12405	COG2153	protein acetylation
B4067_RS12415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4067_RS12420	COG1846	Transcriptional regulator
B4067_RS12425	COG2153	protein acetylation
B4067_RS12430	COG2364	Membrane
B4067_RS12435	COG0456	acetyltransferase
B4067_RS12440	COG2315	Protein conserved in bacteria
B4067_RS12445	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B4067_RS12450	COG2814	Major facilitator Superfamily
B4067_RS12455	COG1331	Highly conserved protein containing a thioredoxin domain
B4067_RS12460	COG1266	CAAX protease self-immunity
B4067_RS12470	COG0110	maltose O-acetyltransferase activity
B4067_RS12475	COG0346	lactoylglutathione lyase activity
B4067_RS12480	COG1609	Transcriptional regulator
B4067_RS12485	COG0708	Exodeoxyribonuclease III
B4067_RS12490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B4067_RS12495	COG0629	single-stranded DNA binding
B4067_RS12500	COG0360	Binds together with S18 to 16S ribosomal RNA
B4067_RS12505	COG0012	GTP binding
B4067_RS12510	COG0243	molybdopterin cofactor binding
B4067_RS12515	COG4481	Protein conserved in bacteria
B4067_RS12520	COG3949	Membrane
B4067_RS12530	COG1475	DNA binding
B4067_RS12535	COG1192	Involved in chromosome partitioning
B4067_RS12545	COG1475	DNA binding
B4067_RS12550	COG0357	Ribosomal RNA small subunit methyltransferase G
B4067_RS12555	COG0445	tRNA wobble uridine modification
B4067_RS12560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B4067_RS12565	COG1847	R3H domain protein
B4067_RS12570	COG0706	membrane insertase activity
B4067_RS12575	COG0594	ribonuclease P activity
B4067_RS12585	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B4067_RS12590	COG0592	DNA-directed DNA polymerase activity
B4067_RS12595	COG2501	S4 domain
B4067_RS12600	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B4067_RS12610	COG0187	DNA topoisomerase II activity
B4067_RS12615	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B4067_RS12620	COG3361	conserved protein (COG2071)
B4067_RS12625	COG0706	membrane insertase activity
B4067_RS12635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B4067_RS12640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B4067_RS12645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B4067_RS12650	COG1234	tRNA 3'-trailer cleavage
B4067_RS12670	COG0741	lytic transglycosylase activity
B4067_RS12670	COG0791	NLP P60 protein
B4067_RS12685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B4067_RS12690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B4067_RS12695	COG1316	TRANSCRIPTIONal
B4067_RS12705	COG2247	cell wall binding repeat
B4067_RS12705	COG2385	sporulation resulting in formation of a cellular spore
B4067_RS12710	COG0860	N-Acetylmuramoyl-L-alanine amidase
B4067_RS12710	COG2247	cell wall binding repeat
B4067_RS12720	COG2244	polysaccharide biosynthetic process
B4067_RS12725	COG0297	glycogen (starch) synthase activity
B4067_RS12725	COG0438	transferase activity, transferring glycosyl groups
B4067_RS12730	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B4067_RS12735	COG3307	-O-antigen
B4067_RS12740	COG3206	protein involved in exopolysaccharide biosynthesis
B4067_RS12745	COG1215	transferase activity, transferring glycosyl groups
B4067_RS12750	COG0438	transferase activity, transferring glycosyl groups
B4067_RS12755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B4067_RS12760	COG1316	TRANSCRIPTIONal
B4067_RS12765	COG1739	Uncharacterized protein family UPF0029
B4067_RS12770	COG4585	Histidine kinase
B4067_RS12775	COG2197	response regulator
B4067_RS12780	COG1307	EDD domain protein, DegV family
B4067_RS12785	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B4067_RS12795	COG1040	competence protein
B4067_RS12805	COG2747	anti-sigma28 factor FlgM
B4067_RS12810	COG3418	PFAM FlgN family protein
B4067_RS12815	COG1256	bacterial-type flagellum assembly
B4067_RS12815	COG4786	Flagellar basal body rod
B4067_RS12820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B4067_RS12830	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
B4067_RS12835	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B4067_RS12845	COG1113	amino acid transport
B4067_RS12850	COG3858	chitin binding
B4067_RS12855	COG1556	Lactate utilization protein
B4067_RS12860	COG1139	Iron-sulfur cluster binding protein
B4067_RS12865	COG0247	lactate metabolic process
B4067_RS12870	COG2197	response regulator
B4067_RS12875	COG4585	Histidine kinase
B4067_RS12880	COG0842	Transport permease protein
B4067_RS12885	COG1131	(ABC) transporter
B4067_RS12890	COG0596	Alpha beta hydrolase
B4067_RS12895	COG2208	phosphoserine phosphatase activity
B4067_RS12900	COG3867	Arabinogalactan endo-beta-1,4-galactanase
B4067_RS12905	COG1874	Beta-galactosidase
B4067_RS12910	COG3833	ABC-type maltose transport systems, permease component
B4067_RS12915	COG1175	transmembrane transport
B4067_RS12920	COG2182	Extracellular solute-binding protein
B4067_RS12925	COG1609	Transcriptional regulator
B4067_RS12930	COG2186	Transcriptional regulator
B4067_RS12935	COG1620	l-lactate permease
B4067_RS12940	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B4067_RS12950	COG5039	Polysaccharide pyruvyl transferase
B4067_RS12955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B4067_RS12960	COG0110	maltose O-acetyltransferase activity
B4067_RS12965	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B4067_RS12970	COG2244	polysaccharide biosynthetic process
B4067_RS12975	COG1216	Glycosyl transferase, family 2
B4067_RS12980	COG5039	Polysaccharide pyruvyl transferase
B4067_RS12985	COG1216	Glycosyl transferase, family 2
B4067_RS12995	COG0438	transferase activity, transferring glycosyl groups
B4067_RS13000	COG1215	transferase activity, transferring glycosyl groups
B4067_RS13005	COG0438	transferase activity, transferring glycosyl groups
B4067_RS13010	COG1086	Polysaccharide biosynthesis protein
B4067_RS13015	COG0489	protein tyrosine kinase activity
B4067_RS13020	COG3944	biosynthesis protein
B4067_RS13025	COG1396	sequence-specific DNA binding
B4067_RS13030	COG2272	Belongs to the type-B carboxylesterase lipase family
B4067_RS13040	COG3479	Phenolic acid decarboxylase
B4067_RS13050	COG1794	racemase activity, acting on amino acids and derivatives
B4067_RS13055	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B4067_RS13065	COG1621	beta-fructofuranosidase activity
B4067_RS13070	COG1621	beta-fructofuranosidase activity
B4067_RS13080	COG1309	transcriptional regulator
B4067_RS13085	COG2076	Multidrug Resistance protein
B4067_RS13090	COG2076	Multidrug Resistance protein
B4067_RS13105	COG0740	serine-type endopeptidase activity
B4067_RS13110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B4067_RS13115	COG0366	Alpha amylase catalytic
B4067_RS13120	COG1554	hydrolase, family 65, central catalytic
B4067_RS13125	COG5521	maltodextrose utilization protein MalA
B4067_RS13130	COG3833	ABC-type maltose transport systems, permease component
B4067_RS13135	COG1175	transmembrane transport
B4067_RS13140	COG2182	Extracellular solute-binding protein
B4067_RS13145	COG0366	Alpha amylase catalytic
B4067_RS13150	COG1609	Transcriptional regulator
B4067_RS13155	COG1611	Belongs to the LOG family
B4067_RS13160	COG1694	Mazg nucleotide pyrophosphohydrolase
B4067_RS13165	COG0659	secondary active sulfate transmembrane transporter activity
B4067_RS13170	COG0288	reversible hydration of carbon dioxide
B4067_RS13175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B4067_RS13180	COG0577	efflux transmembrane transporter activity
B4067_RS13185	COG1136	(ABC) transporter
B4067_RS13190	COG5002	protein histidine kinase activity
B4067_RS13195	COG0745	RESPONSE REGULATOR receiver
B4067_RS13205	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B4067_RS13210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B4067_RS13215	COG1481	regulation of sporulation
B4067_RS13220	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B4067_RS13225	COG1660	Displays ATPase and GTPase activities
B4067_RS13230	COG1051	belongs to the nudix hydrolase family
B4067_RS13235	COG0492	ferredoxin-NADP+ reductase activity
B4067_RS13240	COG0791	NLP P60 protein
B4067_RS13240	COG3883	PFAM NLP P60 protein
B4067_RS13245	COG0457	Tetratricopeptide repeat
B4067_RS13250	COG1132	(ABC) transporter
B4067_RS13270	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B4067_RS13270	COG0140	phosphoribosyl-ATP diphosphatase activity
B4067_RS13275	COG0107	imidazoleglycerol-phosphate synthase activity
B4067_RS13280	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B4067_RS13285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B4067_RS13290	COG0131	Imidazoleglycerol-phosphate dehydratase
B4067_RS13295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B4067_RS13300	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B4067_RS13305	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B4067_RS13310	COG4990	cell redox homeostasis
B4067_RS13320	COG0110	maltose O-acetyltransferase activity
B4067_RS13325	COG0546	phosphoglycolate phosphatase activity
B4067_RS13330	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B4067_RS13335	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B4067_RS13340	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B4067_RS13345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B4067_RS13350	COG0363	glucosamine-6-phosphate deaminase activity
B4067_RS13355	COG2188	Transcriptional regulator
B4067_RS13360	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B4067_RS13365	COG1846	Transcriptional regulator
B4067_RS13370	COG2814	Major facilitator Superfamily
B4067_RS13375	COG1950	PFAM Membrane protein of
B4067_RS13380	COG1983	PspC domain protein
B4067_RS13385	COG3595	metallopeptidase activity
B4067_RS13400	COG0662	Cupin 2, conserved barrel domain protein
B4067_RS13405	COG1525	nuclease
B4067_RS13410	COG2814	Major facilitator Superfamily
B4067_RS13415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B4067_RS13425	COG0756	dUTP diphosphatase activity
B4067_RS13460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B4067_RS13475	COG3832	glyoxalase III activity
B4067_RS13490	COG0697	spore germination
B4067_RS13495	COG0531	amino acid
B4067_RS13525	COG4195	phage-related replication protein
B4067_RS13535	COG0346	lactoylglutathione lyase activity
B4067_RS13545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B4067_RS13550	COG1388	LysM domain
B4067_RS13555	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B4067_RS13560	COG4224	UPF0291 protein
B4067_RS13565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B4067_RS13575	COG3763	UPF0154 protein
B4067_RS13585	COG0785	Cytochrome C biogenesis protein
B4067_RS13590	COG2201	protein-glutamate methylesterase activity
B4067_RS13595	COG4846	Membrane protein involved in cytochrome C biogenesis
B4067_RS13600	COG5644	endopeptidase inhibitor activity
B4067_RS13635	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4067_RS13635	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS13755	COG1783	phage Terminase large subunit
B4067_RS13760	COG5484	DNA packaging
B4067_RS13795	COG0457	Tetratricopeptide repeat
B4067_RS13800	COG1063	alcohol dehydrogenase
B4067_RS13805	COG2211	Major facilitator Superfamily
B4067_RS13810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B4067_RS13815	COG1842	Phage shock protein A
B4067_RS13820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B4067_RS13825	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B4067_RS13830	COG4260	virion core protein, lumpy skin disease virus
B4067_RS13840	COG2814	Major facilitator Superfamily
B4067_RS13845	COG1063	alcohol dehydrogenase
B4067_RS13850	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B4067_RS13855	COG0823	Involved in the tonB-independent uptake of proteins
B4067_RS13860	COG2814	Major facilitator Superfamily
B4067_RS13870	COG1413	lyase activity
B4067_RS13875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4067_RS13880	COG1937	Protein conserved in bacteria
B4067_RS13885	COG2210	Belongs to the sulfur carrier protein TusA family
B4067_RS13890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B4067_RS13890	COG0425	Belongs to the sulfur carrier protein TusA family
B4067_RS13900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B4067_RS13900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4067_RS13905	COG0425	Belongs to the sulfur carrier protein TusA family
B4067_RS13910	COG0730	response to heat
B4067_RS13915	COG4124	Belongs to the glycosyl hydrolase 26 family
B4067_RS13935	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B4067_RS13935	COG1215	transferase activity, transferring glycosyl groups
B4067_RS13940	COG0463	Glycosyl transferase, family 2
B4067_RS14035	COG1396	sequence-specific DNA binding
B4067_RS14050	COG2003	Belongs to the UPF0758 family
B4067_RS14055	COG0424	maF-like protein
B4067_RS14065	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B4067_RS14070	COG0285	dihydrofolate synthase activity
B4067_RS14075	COG0525	valine-tRNA ligase activity
B4067_RS14085	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B4067_RS14090	COG1388	LysM domain
B4067_RS14095	COG0697	spore germination
B4067_RS14110	COG0456	acetyltransferase
B4067_RS14120	COG0789	Transcriptional regulator
B4067_RS14120	COG4978	Transcriptional regulator
B4067_RS14135	COG0662	Cupin 2, conserved barrel domain protein
B4067_RS14145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B4067_RS14155	COG1664	Polymer-forming cytoskeletal
B4067_RS14160	COG0789	Transcriptional regulator
B4067_RS14165	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B4067_RS14175	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B4067_RS14180	COG3382	B3 4 domain protein
B4067_RS14190	COG1476	TRANSCRIPTIONal
B4067_RS14200	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B4067_RS14210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B4067_RS14215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B4067_RS14220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B4067_RS14225	COG1116	anion transmembrane transporter activity
B4067_RS14230	COG0753	catalase activity
B4067_RS14245	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B4067_RS14250	COG3340	Belongs to the peptidase S51 family
B4067_RS14255	COG5577	PFAM Coat F domain
B4067_RS14265	COG4326	sporulation control protein
B4067_RS14275	COG0534	Mate efflux family protein
B4067_RS14280	COG2017	converts alpha-aldose to the beta-anomer
B4067_RS14285	COG2027	D-alanyl-D-alanine carboxypeptidase
B4067_RS14320	COG1960	acyl-CoA dehydrogenase activity
B4067_RS14325	COG0318	PFAM AMP-dependent synthetase and ligase
B4067_RS14330	COG0439	Biotin carboxylase
B4067_RS14335	COG0511	ligase activity, forming carbon-carbon bonds
B4067_RS14340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B4067_RS14345	COG1024	Enoyl-CoA hydratase
B4067_RS14350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B4067_RS14355	COG2404	hydrolase activity, acting on ester bonds
B4067_RS14360	COG0586	Pfam SNARE associated Golgi protein
B4067_RS14365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B4067_RS14370	COG2246	polysaccharide biosynthetic process
B4067_RS14375	COG3507	Belongs to the glycosyl hydrolase 43 family
B4067_RS14390	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B4067_RS14395	COG1115	amino acid carrier protein
B4067_RS14410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B4067_RS14415	COG0187	DNA topoisomerase II activity
B4067_RS14420	COG1832	CoA-binding protein
B4067_RS14425	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B4067_RS14430	COG4841	protein insertion into membrane
B4067_RS14440	COG0824	Thioesterase
B4067_RS14460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4067_RS14465	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B4067_RS14480	COG0071	Belongs to the small heat shock protein (HSP20) family
B4067_RS14495	COG0387	Pfam Sodium calcium exchanger
B4067_RS14505	COG0477	Major facilitator Superfamily
B4067_RS14515	COG1295	ribonuclease BN
B4067_RS14520	COG4980	gas vesicle protein
B4067_RS14525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B4067_RS14530	COG4840	Belongs to the UPF0435 family
B4067_RS14535	COG2814	Major facilitator Superfamily
B4067_RS14540	COG0693	protein deglycase activity
B4067_RS14545	COG0737	Belongs to the 5'-nucleotidase family
B4067_RS14550	COG0778	Nitroreductase
B4067_RS14555	COG2188	Transcriptional regulator
B4067_RS14560	COG0366	Alpha amylase catalytic
B4067_RS14565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4067_RS14565	COG1263	PTS System
B4067_RS14570	COG0697	spore germination
B4067_RS14580	COG1368	sulfuric ester hydrolase activity
B4067_RS14610	COG2856	Zn peptidase
B4067_RS14625	COG3620	sequence-specific DNA binding
B4067_RS14630	COG1476	TRANSCRIPTIONal
B4067_RS14655	COG5377	YqaJ viral recombinase family
B4067_RS14660	COG3723	Recombinational DNA repair protein, rece pathway
B4067_RS14665	COG3935	DnaD domain protein
B4067_RS14670	COG1484	DNA-dependent DNA replication
B4067_RS14685	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B4067_RS14700	COG3677	Transposase
B4067_RS14730	COG1476	TRANSCRIPTIONal
B4067_RS14740	COG3239	Fatty acid desaturase
B4067_RS14745	COG1278	Cold shock
B4067_RS14750	COG1329	Transcriptional regulator
B4067_RS14760	COG2972	Histidine kinase
B4067_RS14760	COG0745	RESPONSE REGULATOR receiver
B4067_RS14765	COG3764	Sortase (surface protein transpeptidase)
B4067_RS14780	COG0629	single-stranded DNA binding
B4067_RS14785	COG1349	DNA-binding transcription factor activity
B4067_RS14790	COG0561	phosphatase activity
B4067_RS14795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B4067_RS14800	COG4715	Zinc finger, swim domain protein
B4067_RS14810	COG3944	biosynthesis protein
B4067_RS14815	COG0489	protein tyrosine kinase activity
B4067_RS14820	COG4464	protein tyrosine phosphatase activity
B4067_RS14825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B4067_RS14830	COG3878	Protein conserved in bacteria
B4067_RS14845	COG5444	nuclease activity
B4067_RS14875	COG2059	Chromate
B4067_RS14880	COG2059	Chromate
B4067_RS14885	COG1522	sequence-specific DNA binding
B4067_RS14890	COG0405	Gamma-glutamyltransferase
B4067_RS14900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B4067_RS14910	COG5337	Spore coat protein CotH
B4067_RS14930	COG0583	DNA-binding transcription factor activity
B4067_RS14935	COG0028	Belongs to the TPP enzyme family
B4067_RS14940	COG3527	Alpha-acetolactate decarboxylase
B4067_RS14945	COG2249	NAD(P)H dehydrogenase (quinone) activity
B4067_RS14955	COG3103	Sh3 type 3 domain protein
B4067_RS14960	COG1879	ABC-type sugar transport system periplasmic component
B4067_RS14965	COG1172	Belongs to the binding-protein-dependent transport system permease family
B4067_RS14970	COG1129	ABC transporter
B4067_RS14980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B4067_RS14985	COG1609	Transcriptional regulator
B4067_RS14990	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B4067_RS15000	COG2843	Capsule synthesis protein
B4067_RS15010	COG0791	NLP P60 protein
B4067_RS15015	COG0561	phosphatase activity
B4067_RS15020	COG1316	TRANSCRIPTIONal
B4067_RS15025	COG2814	Major facilitator Superfamily
B4067_RS15035	COG0814	amino acid
B4067_RS15050	COG1482	cell wall glycoprotein biosynthetic process
B4067_RS15055	COG4193	domain, Protein
B4067_RS15065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B4067_RS15070	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
B4067_RS15075	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B4067_RS15080	COG0438	transferase activity, transferring glycosyl groups
B4067_RS15085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B4067_RS15090	COG1682	transport, permease protein
B4067_RS15095	COG1134	teichoic acid transport
B4067_RS15100	COG0640	Transcriptional regulator
B4067_RS15105	COG5609	conserved protein (DUF2294)
B4067_RS15115	COG0288	reversible hydration of carbon dioxide
B4067_RS15120	COG3002	Belongs to the UPF0753 family
B4067_RS15125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B4067_RS15130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B4067_RS15135	COG2169	Transcriptional regulator
B4067_RS15145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B4067_RS15150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B4067_RS15155	COG4856	YbbR-like protein
B4067_RS15160	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B4067_RS15165	COG5662	AntiSigma factor
B4067_RS15170	COG1595	DNA-templated transcription, initiation
B4067_RS15185	COG1683	Conserved Protein
B4067_RS15195	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B4067_RS15200	COG1737	Transcriptional regulator
B4067_RS15205	COG1263	PTS System
B4067_RS15205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4067_RS15210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B4067_RS15215	COG1472	Belongs to the glycosyl hydrolase 3 family
B4067_RS15220	COG3876	Protein conserved in bacteria
B4067_RS15225	COG2207	Transcriptional regulator
B4067_RS15225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4067_RS15230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4067_RS15235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4067_RS15240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4067_RS15245	COG2819	hydrolase of the alpha beta superfamily
B4067_RS15250	COG0385	Bile acid
B4067_RS15255	COG0659	secondary active sulfate transmembrane transporter activity
B4067_RS15270	COG0741	lytic transglycosylase activity
B4067_RS15275	COG0640	Transcriptional regulator
B4067_RS15285	COG2378	regulation of single-species biofilm formation
B4067_RS15290	COG3708	Transcriptional regulator
B4067_RS15295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4067_RS15300	COG1309	transcriptional regulator
B4067_RS15305	COG0456	acetyltransferase
B4067_RS15310	COG0662	Cupin 2, conserved barrel domain protein
B4067_RS15310	COG2207	Transcriptional regulator
B4067_RS15315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B4067_RS15325	COG1231	oxidoreductase activity
B4067_RS15330	COG4282	regulation of fungal-type cell wall biogenesis
B4067_RS15335	COG5444	nuclease activity
B4067_RS15350	COG0693	protein deglycase activity
B4067_RS15360	COG0582	viral genome integration into host DNA
B4067_RS15365	COG0166	Belongs to the GPI family
B4067_RS15370	COG0405	Gamma-glutamyltransferase
B4067_RS15375	COG0583	DNA-binding transcription factor activity
B4067_RS15380	COG0604	alcohol dehydrogenase
B4067_RS15400	COG2910	NAD(P)H-binding
B4067_RS15405	COG1959	2 iron, 2 sulfur cluster binding
B4067_RS15410	COG0804	urea catabolic process
B4067_RS15415	COG0832	Belongs to the urease beta subunit family
B4067_RS15420	COG0831	urea catabolic process
B4067_RS15450	COG3237	CsbD-like
B4067_RS15455	COG1994	Peptidase M50
B4067_RS15460	COG0457	Tetratricopeptide repeat
B4067_RS15465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B4067_RS15470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B4067_RS15480	COG2304	oxidoreductase activity
B4067_RS15490	COG2304	oxidoreductase activity
B4067_RS15495	COG2385	sporulation resulting in formation of a cellular spore
B4067_RS15500	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B4067_RS15510	COG4836	Membrane
B4067_RS15520	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B4067_RS15525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B4067_RS15530	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B4067_RS15535	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B4067_RS15540	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B4067_RS15545	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B4067_RS15560	COG0356	it plays a direct role in the translocation of protons across the membrane
B4067_RS15570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B4067_RS15575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B4067_RS15580	COG4475	Protein of unknown function (DUF436)
B4067_RS15585	COG0698	ribose 5-phosphate isomerase
B4067_RS15590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B4067_RS15595	COG1971	Probably functions as a manganese efflux pump
B4067_RS15600	COG0009	L-threonylcarbamoyladenylate synthase
B4067_RS15605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B4067_RS15625	COG2890	protein-(glutamine-N5) methyltransferase activity
B4067_RS15630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B4067_RS15635	COG0346	lactoylglutathione lyase activity
B4067_RS15640	COG0789	Transcriptional regulator
B4067_RS15645	COG0679	Auxin Efflux Carrier
B4067_RS15650	COG0281	malic enzyme
B4067_RS15655	COG1435	thymidine kinase activity
B4067_RS15665	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B4067_RS15675	COG1494	fructose-1,6-bisphosphatase
B4067_RS15680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B4067_RS15685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B4067_RS15690	COG0191	fructose-bisphosphate aldolase activity
B4067_RS15695	COG2204	response regulator
B4067_RS15700	COG4821	SIS domain
B4067_RS15715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B4067_RS15720	COG1301	dicarboxylic acid transport
B4067_RS15730	COG0363	glucosamine-6-phosphate deaminase activity
B4067_RS15735	COG2188	Transcriptional regulator
B4067_RS15745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B4067_RS15755	COG1482	cell wall glycoprotein biosynthetic process
B4067_RS15760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B4067_RS15760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B4067_RS15760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B4067_RS15765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B4067_RS15765	COG3711	transcriptional antiterminator
B4067_RS15775	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B4067_RS15790	COG0072	phenylalanine-tRNA ligase activity
B4067_RS15790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B4067_RS15800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4067_RS15805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4067_RS15810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B4067_RS15815	COG0508	dehydrogenase complex catalyzes the overall conversion of
B4067_RS15820	COG0022	dehydrogenase e1 component
B4067_RS15825	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B4067_RS15830	COG0497	DNA recombination
B4067_RS15840	COG0242	peptide deformylase activity
B4067_RS15845	COG0561	phosphatase activity
B4067_RS15850	COG5503	Protein of unknown function (DUF1447)
B4067_RS15855	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B4067_RS15860	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B4067_RS15865	COG0569	domain protein
B4067_RS15870	COG2105	PFAM AIG2 family protein
B4067_RS15870	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
B4067_RS15880	COG2002	toxin-antitoxin pair type II binding
B4067_RS15885	COG1077	Cell shape determining protein MreB Mrl
B4067_RS15895	COG2309	aminopeptidase activity
B4067_RS15900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B4067_RS15905	COG0488	(ABC) transporter
B4067_RS15915	COG0681	Belongs to the peptidase S26 family
B4067_RS15920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B4067_RS15920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B4067_RS15920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B4067_RS15925	COG1105	Belongs to the carbohydrate kinase PfkB family
B4067_RS15930	COG1349	DNA-binding transcription factor activity
B4067_RS15935	COG0577	efflux transmembrane transporter activity
B4067_RS15940	COG1136	(ABC) transporter
B4067_RS15945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B4067_RS15955	COG1132	(ABC) transporter
B4067_RS15960	COG1132	(ABC) transporter
B4067_RS15965	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B4067_RS15970	COG0314	molybdopterin synthase activity
B4067_RS15975	COG1763	Mo-molybdopterin cofactor biosynthetic process
B4067_RS15980	COG0303	'Molybdopterin
B4067_RS15985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B4067_RS15990	COG0746	molybdenum cofactor guanylyltransferase activity
B4067_RS16000	COG0587	DNA-directed DNA polymerase activity
B4067_RS16005	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B4067_RS16010	COG0358	DNA primase activity
B4067_RS16015	COG0305	Participates in initiation and elongation during chromosome replication
B4067_RS16025	COG2887	Belongs to the helicase family. UvrD subfamily
B4067_RS16065	COG5444	nuclease activity
B4067_RS16085	COG2323	membrane
B4067_RS16120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B4067_RS16125	COG1054	Belongs to the UPF0176 family
B4067_RS16130	COG2312	Erythromycin esterase
B4067_RS16140	COG0688	phosphatidylethanolamine metabolic process
B4067_RS16145	COG0586	Pfam SNARE associated Golgi protein
B4067_RS16150	COG1183	phosphatidylcholine synthase activity
B4067_RS16155	COG0596	Alpha beta hydrolase
B4067_RS16170	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B4067_RS16175	COG1917	Cupin 2, conserved barrel domain protein
B4067_RS16175	COG2207	Transcriptional regulator
B4067_RS16180	COG0697	spore germination
B4067_RS16195	COG2271	Major facilitator Superfamily
B4067_RS16200	COG1846	Transcriptional regulator
B4067_RS16200	COG0456	acetyltransferase
B4067_RS16210	COG2271	Major facilitator Superfamily
B4067_RS16215	COG0584	glycerophosphoryl diester phosphodiesterase
B4067_RS16230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B4067_RS16235	COG0322	excinuclease ABC activity
B4067_RS16240	COG2222	sugar isomerase
B4067_RS16245	COG1653	transport
B4067_RS16250	COG1175	transmembrane transport
B4067_RS16260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B4067_RS16265	COG2188	Transcriptional regulator
B4067_RS16270	COG3842	ATPase activity
B4067_RS16295	COG1070	Carbohydrate kinase
B4067_RS16300	COG2115	Belongs to the xylose isomerase family
B4067_RS16305	COG1940	carbohydrate kinase activity
B4067_RS16310	COG3507	Belongs to the glycosyl hydrolase 43 family
B4067_RS16315	COG2211	Major facilitator Superfamily
B4067_RS16325	COG3859	Proton-coupled thiamine transporter YuaJ
B4067_RS16330	COG1247	-acetyltransferase
B4067_RS16335	COG2268	Band 7 protein
B4067_RS16340	COG1585	Membrane protein implicated in regulation of membrane protease activity
B4067_RS16345	COG2318	DinB family
B4067_RS16355	COG1454	alcohol dehydrogenase
B4067_RS16360	COG1012	belongs to the aldehyde dehydrogenase family
B4067_RS16365	COG1510	regulation of RNA biosynthetic process
B4067_RS16375	COG1764	response to oxidative stress
B4067_RS16380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B4067_RS16385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B4067_RS16390	COG0788	formyltetrahydrofolate deformylase activity
B4067_RS16395	COG2076	Multidrug Resistance protein
B4067_RS16400	COG2076	Multidrug Resistance protein
B4067_RS16405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4067_RS16410	COG2318	DinB family
B4067_RS16415	COG2323	membrane
B4067_RS16425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B4067_RS16425	COG1017	nitric oxide dioxygenase activity
B4067_RS16430	COG1607	acyl-coa hydrolase
B4067_RS16435	COG1834	amidinotransferase
B4067_RS16440	COG2706	6-phosphogluconolactonase activity
B4067_RS16445	COG4608	Belongs to the ABC transporter superfamily
B4067_RS16450	COG0791	NLP P60 protein
B4067_RS16455	COG4948	Mandelate Racemase Muconate Lactonizing
B4067_RS16460	COG1619	proteins homologs of microcin C7 resistance protein MccF
B4067_RS16465	COG4166	transmembrane transport
B4067_RS16470	COG0444	Belongs to the ABC transporter superfamily
B4067_RS16475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B4067_RS16480	COG0601	transmembrane transport
B4067_RS16485	COG2362	D-Aminopeptidase
B4067_RS16490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B4067_RS16495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B4067_RS16505	COG0463	Glycosyl transferase, family 2
B4067_RS16510	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B4067_RS16515	COG0346	lactoylglutathione lyase activity
B4067_RS16520	COG0531	amino acid
B4067_RS16525	COG1392	Phosphate transport regulator
B4067_RS16530	COG0306	phosphate transporter
B4067_RS16545	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS16545	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4067_RS16585	COG3778	Protein conserved in bacteria
B4067_RS16590	COG3299	homolog of phage Mu protein gp47
B4067_RS16595	COG3628	GPW Gp25 family protein
B4067_RS16605	COG4193	domain, Protein
B4067_RS16610	COG1652	LysM domain
B4067_RS16615	COG5412	phage tail tape measure protein
B4067_RS16615	COG3953	SLT domain
B4067_RS16665	COG4653	Phage capsid family
B4067_RS16670	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B4067_RS16675	COG5518	Phage portal protein
B4067_RS16680	COG1783	phage Terminase large subunit
B4067_RS16685	COG5484	DNA packaging
B4067_RS16685	COG3728	DNA packaging
B4067_RS16690	COG1595	DNA-templated transcription, initiation
B4067_RS16715	COG1484	DNA-dependent DNA replication
B4067_RS16720	COG1522	sequence-specific DNA binding
B4067_RS16730	COG1396	sequence-specific DNA binding
B4067_RS16735	COG2856	Zn peptidase
B4067_RS16740	COG4195	phage-related replication protein
B4067_RS16750	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS16750	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4067_RS16750	COG1388	LysM domain
B4067_RS16755	COG2350	Protein conserved in bacteria
B4067_RS16765	COG0457	Tetratricopeptide repeat
B4067_RS16775	COG2318	DinB family
B4067_RS16780	COG0730	response to heat
B4067_RS16785	COG2721	sulfolactate sulfo-lyase activity
B4067_RS16790	COG0246	Mannitol dehydrogenase
B4067_RS16795	COG1609	Transcriptional regulator
B4067_RS16800	COG2271	Major facilitator Superfamily
B4067_RS16805	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS16810	COG1312	Catalyzes the dehydration of D-mannonate
B4067_RS16815	COG1063	alcohol dehydrogenase
B4067_RS16820	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B4067_RS16825	COG2211	Major facilitator Superfamily
B4067_RS16830	COG1904	glucuronate isomerase
B4067_RS16835	COG1252	NADH dehydrogenase
B4067_RS16845	COG4297	protein containing double-stranded beta helix domain
B4067_RS16850	COG0697	spore germination
B4067_RS16855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B4067_RS16860	COG0390	transport system, permease component
B4067_RS16865	COG1587	Uroporphyrinogen-III synthase
B4067_RS16875	COG1819	glycosyl
B4067_RS16880	COG2124	cytochrome p450
B4067_RS16890	COG1051	belongs to the nudix hydrolase family
B4067_RS16900	COG2427	Protein of unknown function (DUF1641)
B4067_RS16915	COG2205	protein histidine kinase activity
B4067_RS16940	COG0726	polysaccharide deacetylase
B4067_RS16950	COG0109	protoheme IX farnesyltransferase activity
B4067_RS16965	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B4067_RS16990	COG0305	Participates in initiation and elongation during chromosome replication
B4067_RS17015	COG3645	SOS response
B4067_RS17015	COG3646	Phage regulatory protein
B4067_RS17045	COG1396	sequence-specific DNA binding
B4067_RS17060	COG0719	Fe-S assembly protein
B4067_RS17065	COG0822	iron-sulfur transferase activity
B4067_RS17070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B4067_RS17075	COG0719	Fe-S assembly protein
B4067_RS17080	COG0396	ATPase activity
B4067_RS17095	COG1464	Belongs to the NlpA lipoprotein family
B4067_RS17100	COG2011	ABC-type metal ion transport system permease component
B4067_RS17105	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B4067_RS17115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4067_RS17120	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B4067_RS17130	COG0509	glycine decarboxylation via glycine cleavage system
B4067_RS17135	COG1393	Belongs to the ArsC family
B4067_RS17140	COG1960	acyl-CoA dehydrogenase activity
B4067_RS17145	COG0183	Belongs to the thiolase family
B4067_RS17150	COG1024	Enoyl-CoA hydratase
B4067_RS17150	COG1250	3-hydroxyacyl-CoA dehydrogenase
B4067_RS17160	COG0506	proline dehydrogenase activity
B4067_RS17170	COG5577	PFAM Coat F domain
B4067_RS17175	COG1846	Transcriptional regulator
B4067_RS17180	COG0477	Major facilitator Superfamily
B4067_RS17185	COG1942	4-Oxalocrotonate Tautomerase
B4067_RS17220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B4067_RS17225	COG5444	nuclease activity
B4067_RS17240	COG2433	Pfam Transposase IS66
B4067_RS17295	COG1705	Flagellar rod assembly protein muramidase FlgJ
B4067_RS17300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B4067_RS17325	COG2323	membrane
B4067_RS17330	COG2801	Transposase and inactivated derivatives
B4067_RS17335	COG2963	transposase activity
B4067_RS17365	COG4282	regulation of fungal-type cell wall biogenesis
B4067_RS17370	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B4067_RS17370	COG1605	Chorismate mutase
B4067_RS17375	COG1609	Transcriptional regulator
B4067_RS17380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B4067_RS17385	COG1360	Flagellar Motor Protein
B4067_RS17390	COG0123	including yeast histone deacetylase and acetoin utilization protein
B4067_RS17395	COG0517	IMP dehydrogenase activity
B4067_RS17400	COG0454	-acetyltransferase
B4067_RS17405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B4067_RS17410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B4067_RS17545	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B4067_RS17570	COG3584	3D domain protein
B4067_RS17620	COG1484	DNA-dependent DNA replication
B4067_RS17625	COG3935	DnaD domain protein
B4067_RS17630	COG3723	Recombinational DNA repair protein, rece pathway
B4067_RS17635	COG5377	YqaJ viral recombinase family
B4067_RS17665	COG3645	SOS response
B4067_RS17665	COG3646	Phage regulatory protein
B4067_RS17675	COG3620	sequence-specific DNA binding
B4067_RS17680	COG1525	nuclease
B4067_RS17690	COG2856	Zn peptidase
B4067_RS17695	COG0824	Thioesterase
B4067_RS17700	COG0346	lactoylglutathione lyase activity
B4067_RS17705	COG0640	Transcriptional regulator
B4067_RS17720	COG5444	nuclease activity
B4067_RS17730	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4067_RS17730	COG1388	LysM domain
B4067_RS17730	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS17735	COG4824	toxin secretion phage lysis holin
B4067_RS17750	COG5434	Belongs to the glycosyl hydrolase 28 family
B4067_RS17765	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4067_RS17765	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS17765	COG1388	LysM domain
B4067_RS17795	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B4067_RS17840	COG0135	phosphoribosylanthranilate isomerase activity
B4067_RS17850	COG0454	-acetyltransferase
B4067_RS17855	COG2153	protein acetylation
B4067_RS17860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B4067_RS17860	COG0646	methionine synthase
B4067_RS17865	COG1666	GTP binding
B4067_RS17870	COG2996	Protein conserved in bacteria
B4067_RS17890	COG1695	Transcriptional regulator
B4067_RS17905	COG3227	Zinc metalloprotease (Elastase)
B4067_RS17910	COG1307	EDD domain protein, DegV family
B4067_RS17915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4067_RS17935	COG0561	phosphatase activity
B4067_RS17940	COG1073	alpha beta
B4067_RS17945	COG2151	metal-sulfur cluster biosynthetic enzyme
B4067_RS17955	COG0277	FAD linked oxidase domain protein
B4067_RS17960	COG2271	Major facilitator Superfamily
B4067_RS17965	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B4067_RS17970	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B4067_RS17980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B4067_RS17985	COG0505	Belongs to the CarA family
B4067_RS17990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B4067_RS17995	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B4067_RS18010	COG2267	carboxylic ester hydrolase activity
B4067_RS18020	COG1744	ABC transporter substrate-binding protein PnrA-like
B4067_RS18035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B4067_RS18040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B4067_RS18045	COG5504	Zn-dependent protease
B4067_RS18050	COG0444	Belongs to the ABC transporter superfamily
B4067_RS18055	COG4608	Belongs to the ABC transporter superfamily
B4067_RS18065	COG0601	transmembrane transport
B4067_RS18070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B4067_RS18080	COG0180	Tryptophanyl-tRNA synthetase
B4067_RS18085	COG4166	transmembrane transport
B4067_RS18090	COG0601	transmembrane transport
B4067_RS18095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B4067_RS18100	COG0444	Belongs to the ABC transporter superfamily
B4067_RS18105	COG4608	Belongs to the ABC transporter superfamily
B4067_RS18110	COG2814	Major facilitator Superfamily
B4067_RS18115	COG0456	acetyltransferase
B4067_RS18120	COG1393	Belongs to the ArsC family
B4067_RS18125	COG0861	Integral membrane protein TerC family
B4067_RS18130	COG4862	establishment of competence for transformation
B4067_RS18135	COG4469	Competence protein
B4067_RS18140	COG1164	Oligoendopeptidase f
B4067_RS18155	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B4067_RS18160	COG2346	COG2346, Truncated hemoglobins
B4067_RS18165	COG0741	lytic transglycosylase activity
B4067_RS18170	COG4116	CYTH
B4067_RS18180	COG2357	RelA SpoT domain protein
B4067_RS18185	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B4067_RS18190	COG0564	pseudouridine synthase activity
B4067_RS18200	COG0475	glutathione-regulated potassium exporter activity
B4067_RS18200	COG0569	domain protein
B4067_RS18205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B4067_RS18210	COG0352	thiamine-phosphate diphosphorylase activity
B4067_RS18220	COG2104	thiamine diphosphate biosynthetic process
B4067_RS18225	COG2022	thiamine diphosphate biosynthetic process
B4067_RS18230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B4067_RS18235	COG0351	phosphomethylpyrimidine kinase
B4067_RS18240	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B4067_RS18300	COG0210	DNA helicase
B4067_RS18310	COG2153	protein acetylation
B4067_RS18315	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B4067_RS18320	COG2382	esterase
B4067_RS18325	COG0626	cystathionine gamma-synthase activity
B4067_RS18330	COG0626	cystathionine gamma-synthase activity
B4067_RS18335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4067_RS18340	COG5505	Protein of unknown function (DUF819)
B4067_RS18350	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B4067_RS18480	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B4067_RS18480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B4067_RS18495	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B4067_RS18520	COG1780	Probably involved in ribonucleotide reductase function
B4067_RS18530	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B4067_RS18535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B4067_RS18540	COG0756	dUTP diphosphatase activity
B4067_RS18550	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
B4067_RS18555	COG3584	3D domain protein
B4067_RS18555	COG1388	LysM domain
B4067_RS18625	COG0582	viral genome integration into host DNA
B4067_RS18710	COG5434	Belongs to the glycosyl hydrolase 28 family
B4067_RS18735	COG1388	LysM domain
B4067_RS18735	COG3409	Peptidoglycan-binding domain 1 protein
B4067_RS18735	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4067_RS18765	COG1674	ftsk spoiiie
B4067_RS18795	COG1802	Transcriptional regulator
B4067_RS18795	COG4626	Terminase
B4067_RS18835	COG0590	tRNA wobble adenosine to inosine editing
B4067_RS18845	COG1764	response to oxidative stress
B4067_RS18850	COG1846	Transcriptional regulator
B4067_RS18885	COG2267	carboxylic ester hydrolase activity
B4067_RS18895	COG2132	Multicopper oxidase
B4067_RS18900	COG1113	amino acid transport
B4067_RS18910	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B4067_RS18915	COG0714	Associated with various cellular activities
B4067_RS18920	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
B4067_RS18925	COG1305	Transglutaminase-like
B4067_RS18930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B4067_RS18930	COG0519	Catalyzes the synthesis of GMP from XMP
B4067_RS18945	COG2252	PERMEase
B4067_RS18950	COG3064	Membrane
B4067_RS18960	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
B4067_RS18970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B4067_RS18975	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B4067_RS18980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B4067_RS18985	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B4067_RS18990	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B4067_RS18995	COG0047	phosphoribosylformylglycinamidine synthase activity
B4067_RS19000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B4067_RS19005	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B4067_RS19010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B4067_RS19015	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B4067_RS19020	COG0138	bifunctional purine biosynthesis protein purh
B4067_RS19025	COG0151	Belongs to the GarS family
B4067_RS19035	COG0531	amino acid
B4067_RS19045	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B4067_RS19050	COG1470	cell adhesion involved in biofilm formation
B4067_RS19055	COG4496	protein, YerC YecD
B4067_RS19070	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
B4067_RS19075	COG0210	DNA helicase
B4067_RS19080	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B4067_RS19085	COG4851	CamS sex pheromone cAM373 precursor
B4067_RS19090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B4067_RS19095	COG1285	pathogenesis
B4067_RS19100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B4067_RS19105	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B4067_RS19110	COG0154	amidase activity
B4067_RS19115	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B4067_RS19120	COG1309	transcriptional regulator
B4067_RS19125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B4067_RS19130	COG1597	lipid kinase activity
B4067_RS19135	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B4067_RS19145	COG0457	Tetratricopeptide repeat
B4067_RS19165	COG5444	nuclease activity
B4067_RS19175	COG0457	Tetratricopeptide repeat
B4067_RS19185	COG0217	transcriptional regulatory protein
B4067_RS19195	COG1309	transcriptional regulator
B4067_RS19200	COG3631	Ketosteroid isomerase-related protein
B4067_RS19205	COG0702	epimerase
B4067_RS19220	COG3546	catalase activity
B4067_RS19225	COG0454	-acetyltransferase
B4067_RS19235	COG5578	integral membrane protein
B4067_RS19240	COG2972	Histidine kinase
B4067_RS19245	COG4753	response regulator
B4067_RS19245	COG2207	Transcriptional regulator
B4067_RS19250	COG1653	transport
B4067_RS19255	COG1175	transmembrane transport
B4067_RS19260	COG0395	ABC-type sugar transport system, permease component
B4067_RS19265	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B4067_RS19270	COG2207	Transcriptional regulator
B4067_RS19275	COG2755	lipolytic protein G-D-S-L family
B4067_RS19285	COG5578	integral membrane protein
B4067_RS19300	COG2755	lipolytic protein G-D-S-L family
B4067_RS19315	COG1653	transport
B4067_RS19320	COG4209	transmembrane transport
B4067_RS19325	COG0395	ABC-type sugar transport system, permease component
B4067_RS19330	COG1486	melibiose metabolic process
B4067_RS19335	COG2323	membrane
B4067_RS19340	COG2329	Antibiotic biosynthesis monooxygenase
B4067_RS19345	COG0346	lactoylglutathione lyase activity
B4067_RS19360	COG5583	Uncharacterized small protein (DUF2292)
B4067_RS19365	COG0670	Belongs to the BI1 family
B4067_RS19370	COG1846	Transcriptional regulator
B4067_RS19380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B4067_RS19380	COG2124	cytochrome p450
B4067_RS19385	COG1368	sulfuric ester hydrolase activity
B4067_RS19395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B4067_RS19400	COG1442	glycosyl transferase family 8
B4067_RS19405	COG1216	Glycosyl transferase, family 2
B4067_RS19410	COG1442	glycosyl transferase family 8
B4067_RS19415	COG2223	nitrite transmembrane transporter activity
B4067_RS19420	COG1011	Hydrolase
B4067_RS19425	COG0531	amino acid
B4067_RS19430	COG1012	belongs to the aldehyde dehydrogenase family
B4067_RS19435	COG0840	transmembrane signaling receptor activity
B4067_RS19440	COG0488	(ABC) transporter
B4067_RS19450	COG0789	Transcriptional regulator
B4067_RS19475	COG0488	(ABC) transporter
B4067_RS19480	COG0513	Belongs to the DEAD box helicase family
B4067_RS19490	COG3866	Pectate lyase
B4067_RS19495	COG0471	metal ion transport
B4067_RS19500	COG3290	protein histidine kinase activity
B4067_RS19505	COG4565	transcriptional regulatory protein
B4067_RS19510	COG3181	Tripartite tricarboxylate transporter family receptor
B4067_RS19520	COG2851	Citrate transporter
B4067_RS19525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4067_RS19530	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
B4067_RS19535	COG1254	Belongs to the acylphosphatase family
B4067_RS19540	COG2258	MOSC domain
B4067_RS19560	COG0024	Methionine aminopeptidase
B4067_RS19565	COG1263	PTS System
B4067_RS19565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4067_RS19570	COG0583	DNA-binding transcription factor activity
B4067_RS19575	COG0697	spore germination
B4067_RS19585	COG0697	spore germination
B4067_RS19590	COG1917	Cupin 2, conserved barrel domain protein
B4067_RS19590	COG2207	Transcriptional regulator
B4067_RS19595	COG0697	spore germination
B4067_RS19600	COG3708	Transcriptional regulator
B4067_RS19600	COG2207	Transcriptional regulator
B4067_RS19605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4067_RS19610	COG0477	Major facilitator Superfamily
B4067_RS19615	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
B4067_RS19630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B4067_RS19635	COG1309	transcriptional regulator
B4067_RS19640	COG0697	spore germination
B4067_RS19645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4067_RS19650	COG2030	dehydratase
B4067_RS19655	COG3545	Serine hydrolase
B4067_RS19660	COG1733	regulation of RNA biosynthetic process
B4067_RS19665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4067_RS19670	COG0640	Transcriptional regulator
B4067_RS19675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B4067_RS19680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B4067_RS19685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4067_RS19690	COG0697	spore germination
B4067_RS19695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4067_RS19700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B4067_RS19705	COG0640	Transcriptional regulator
B4067_RS19710	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B4067_RS19725	COG4585	Histidine kinase
B4067_RS19730	COG2197	response regulator
B4067_RS19735	COG2409	Drug exporters of the RND superfamily
B4067_RS19740	COG1811	Na channel or pump
B4067_RS19745	COG0789	Transcriptional regulator
B4067_RS19745	COG4978	Transcriptional regulator
B4067_RS19765	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B4067_RS19770	COG0778	Nitroreductase
B4067_RS19775	COG0346	lactoylglutathione lyase activity
B4067_RS19780	COG2259	Doxx family
B4067_RS19785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4067_RS19810	COG2323	membrane
B4067_RS19815	COG0071	Belongs to the small heat shock protein (HSP20) family
B4067_RS19830	COG1309	transcriptional regulator
B4067_RS19840	COG0456	acetyltransferase
B4067_RS19850	COG1113	amino acid transport
B4067_RS19855	COG2318	DinB family
B4067_RS19860	COG1846	Transcriptional regulator
B4067_RS19865	COG2409	Drug exporters of the RND superfamily
B4067_RS19865	COG1033	growth of symbiont in host cell
B4067_RS19870	COG0778	Nitroreductase
B4067_RS19875	COG1846	Transcriptional regulator
B4067_RS19880	COG2814	Major facilitator Superfamily
B4067_RS19885	COG0730	response to heat
B4067_RS19890	COG1802	Transcriptional regulator
B4067_RS19895	COG3858	chitin binding
B4067_RS19895	COG1388	LysM domain
B4067_RS19900	COG1819	glycosyl
B4067_RS19910	COG1785	Belongs to the alkaline phosphatase family
B4067_RS19915	COG5646	InterPro IPR014922
B4067_RS19925	COG0454	-acetyltransferase
B4067_RS19930	COG1078	dGTPase activity
B4067_RS19935	COG1388	LysM domain
B4067_RS19945	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B4067_RS19950	COG1447	Phosphotransferase system cellobiose-specific component IIA
B4067_RS19955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B4067_RS19960	COG2723	6-phospho-beta-galactosidase activity
B4067_RS19965	COG2188	Transcriptional regulator
B4067_RS19970	COG1940	carbohydrate kinase activity
B4067_RS19975	COG1482	cell wall glycoprotein biosynthetic process
B4067_RS19980	COG4124	Belongs to the glycosyl hydrolase 26 family
B4067_RS20025	COG5412	phage tail tape measure protein
B4067_RS20025	COG3953	SLT domain
B4067_RS20035	COG5444	nuclease activity
B4067_RS20045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4067_RS20085	COG3091	SprT-like family
B4067_RS20095	COG2183	response to ionizing radiation
B4067_RS20100	COG2208	phosphoserine phosphatase activity
B4067_RS20105	COG1191	sigma factor activity
B4067_RS20110	COG2172	sigma factor antagonist activity
B4067_RS20115	COG1366	Belongs to the anti-sigma-factor antagonist family
B4067_RS20120	COG2208	phosphoserine phosphatase activity
B4067_RS20125	COG2172	sigma factor antagonist activity
B4067_RS20130	COG1366	Belongs to the anti-sigma-factor antagonist family
B4067_RS20135	COG1366	Belongs to the anti-sigma-factor antagonist family
B4067_RS20140	COG2337	Toxic component of a toxin-antitoxin (TA) module
B4067_RS20145	COG0864	Transcriptional regulator
B4067_RS20150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B4067_RS20155	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B4067_RS20160	COG0736	holo-[acyl-carrier-protein] synthase activity
B4067_RS20165	COG0705	Rhomboid family
B4067_RS20170	COG3428	Bacterial PH domain
B4067_RS20175	COG3402	PFAM membrane-flanked domain
B4067_RS20180	COG0513	Belongs to the DEAD box helicase family
B4067_RS20185	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B4067_RS20190	COG1181	Belongs to the D-alanine--D-alanine ligase family
B4067_RS20195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4067_RS20200	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B4067_RS20380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B4067_RS20385	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B4067_RS20390	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B4067_RS20395	COG0297	glycogen (starch) synthase activity
B4067_RS20400	COG0058	SHG alpha-glucan phosphorylase activity
B4067_RS20440	COG5434	Belongs to the glycosyl hydrolase 28 family
B4067_RS20500	COG1484	DNA-dependent DNA replication
B4067_RS20505	COG3935	DnaD domain protein
B4067_RS20515	COG3723	Recombinational DNA repair protein, rece pathway
B4067_RS20520	COG5377	YqaJ viral recombinase family
B4067_RS20560	COG1396	sequence-specific DNA binding
B4067_RS20575	COG2856	Zn peptidase
B4067_RS20580	COG4974	Belongs to the 'phage' integrase family
B4067_RS20585	COG0459	protein refolding
B4067_RS20595	COG1266	CAAX protease self-immunity
B4067_RS20605	COG0805	protein transport
B4067_RS20610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B4067_RS20615	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B4067_RS20620	COG0315	cyclic pyranopterin monophosphate synthase activity
B4067_RS20625	COG0488	(ABC) transporter
B4067_RS20630	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B4067_RS20635	COG0456	acetyltransferase
B4067_RS20640	COG1214	PFAM Peptidase M22, glycoprotease
B4067_RS20645	COG0802	atpase or kinase
B4067_RS20650	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B4067_RS20705	COG2801	Transposase and inactivated derivatives
B4067_RS20720	COG1982	Orn Lys Arg decarboxylase major
B4067_RS20725	COG4476	Belongs to the UPF0223 family
B4067_RS20730	COG4493	Belongs to the UPF0637 family
B4067_RS20740	COG0483	inositol monophosphate 1-phosphatase activity
B4067_RS20750	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B4067_RS20770	COG1595	DNA-templated transcription, initiation
B4067_RS20790	COG1217	gtp-binding protein TYPA
B4067_RS20800	COG4896	Protein conserved in bacteria
B4067_RS20810	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B4067_RS20815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B4067_RS20820	COG2066	Belongs to the glutaminase family
B4067_RS20825	COG4838	Belongs to the UPF0358 family
B4067_RS20830	COG0772	Belongs to the SEDS family
B4067_RS20835	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B4067_RS20840	COG1612	heme a metabolic process
B4067_RS20845	COG0109	protoheme IX farnesyltransferase activity
B4067_RS20850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B4067_RS20850	COG2010	Cytochrome c
B4067_RS20860	COG1845	cytochrome c oxidase, subunit III
B4067_RS20865	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B4067_RS20870	COG3336	cytochrome c oxidase
B4067_RS20880	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
B4067_RS20885	COG2340	Cysteine-rich secretory protein family
B4067_RS20900	COG3679	Belongs to the UPF0342 family
B4067_RS20905	COG4471	UPF0298 protein
B4067_RS20910	COG0742	ribosomal rna small subunit methyltransferase
B4067_RS20915	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B4067_RS20920	COG3314	Sporulation integral membrane protein YlbJ
B4067_RS20925	COG1752	Esterase of the alpha-beta hydrolase superfamily
B4067_RS20930	COG3480	Lon protease (S16) C-terminal proteolytic domain
B4067_RS20935	COG1323	Belongs to the UPF0348 family
B4067_RS20945	COG1399	metal-binding, possibly nucleic acid-binding protein
B4067_RS20960	COG0454	-acetyltransferase
B4067_RS20965	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B4067_RS20970	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
B4067_RS20975	COG2001	Belongs to the MraZ family
B4067_RS20980	COG0275	rRNA processing
B4067_RS20985	COG4839	cell division protein FtsL
B4067_RS20990	COG0768	penicillin binding
B4067_RS21000	COG0768	penicillin binding
B4067_RS21010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B4067_RS21020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B4067_RS21025	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B4067_RS21030	COG0772	Belongs to the SEDS family
B4067_RS21035	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B4067_RS21040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B4067_RS21045	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B4067_RS21050	COG3879	Bacterial protein of unknown function (DUF881)
B4067_RS21055	COG3879	Bacterial protein of unknown function (DUF881)
B4067_RS21060	COG3856	small basic protein
B4067_RS21065	COG0849	cell division
B4067_RS21070	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B4067_RS21075	COG1404	Belongs to the peptidase S8 family
B4067_RS21075	COG4412	M6 family metalloprotease domain protein
B4067_RS21085	COG1191	sigma factor activity
B4067_RS21090	COG1191	sigma factor activity
B4067_RS21095	COG1119	ATPase activity
B4067_RS21100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B4067_RS21105	COG1873	PFAM PRC-barrel domain
B4067_RS21110	COG1496	oxidoreductase activity
B4067_RS21115	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B4067_RS21120	COG1799	cell septum assembly
B4067_RS21125	COG0762	integral membrane protein
B4067_RS21130	COG2302	S4 RNA-binding domain
B4067_RS21135	COG3599	regulation of cell shape
B4067_RS21140	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B4067_RS21145	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B4067_RS21150	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B4067_RS21155	COG0564	pseudouridine synthase activity
B4067_RS21160	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B4067_RS21165	COG2233	PERMEase
B4067_RS21170	COG0540	Belongs to the ATCase OTCase family
B4067_RS21175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B4067_RS21180	COG0505	Belongs to the CarA family
B4067_RS21185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B4067_RS21190	COG0543	2 iron, 2 sulfur cluster binding
B4067_RS21195	COG0167	dihydroorotate dehydrogenase activity
B4067_RS21200	COG0284	orotidine-5'-phosphate decarboxylase activity
B4067_RS21205	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B4067_RS21215	COG0175	sulfate reduction
B4067_RS21220	COG0306	phosphate transporter
B4067_RS21225	COG2046	Belongs to the sulfate adenylyltransferase family
B4067_RS21230	COG0529	Catalyzes the synthesis of activated sulfate
B4067_RS21235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B4067_RS21240	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
B4067_RS21245	COG1648	precorrin-2 dehydrogenase activity
B4067_RS21250	COG1293	RNA-binding protein homologous to eukaryotic snRNP
B4067_RS21255	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B4067_RS21260	COG1561	YicC-like family, N-terminal region
B4067_RS21270	COG0194	GDP metabolic process
B4067_RS21275	COG1758	RNA polymerase activity
B4067_RS21280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B4067_RS21285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B4067_RS21290	COG0242	peptide deformylase activity
B4067_RS21295	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B4067_RS21300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B4067_RS21300	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B4067_RS21305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B4067_RS21310	COG0631	protein serine/threonine phosphatase activity
B4067_RS21315	COG2815	serine threonine protein kinase
B4067_RS21315	COG0515	serine threonine protein kinase
B4067_RS21320	COG1162	GTPase activity
B4067_RS21325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B4067_RS21330	COG1564	THIamine pyrophosphokinase
B4067_RS21340	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B4067_RS21345	COG1302	Protein conserved in bacteria
B4067_RS21350	COG1461	Dihydroxyacetone kinase
B4067_RS21355	COG1760	l-serine dehydratase
B4067_RS21360	COG1760	l-serine dehydratase
B4067_RS21365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B4067_RS21370	COG2050	protein possibly involved in aromatic compounds catabolism
B4067_RS21370	COG1349	DNA-binding transcription factor activity
B4067_RS21375	COG0416	fatty acid biosynthetic process
B4067_RS21380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B4067_RS21385	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS21395	COG0571	ribonuclease III activity
B4067_RS21400	COG1196	nuclear chromosome segregation
B4067_RS21405	COG0552	protein localization to endoplasmic reticulum
B4067_RS21415	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
B4067_RS21420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B4067_RS21425	COG0228	four-way junction DNA binding
B4067_RS21430	COG1837	Belongs to the UPF0109 family
B4067_RS21440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B4067_RS21445	COG0336	Belongs to the RNA methyltransferase TrmD family
B4067_RS21450	COG0335	large ribosomal subunit rRNA binding
B4067_RS21455	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B4067_RS21460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B4067_RS21470	COG2257	FlhB HrpN YscU SpaS Family
B4067_RS21475	COG0045	succinate-CoA ligase (ADP-forming) activity
B4067_RS21480	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B4067_RS21485	COG0758	DNA mediated transformation
B4067_RS21490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B4067_RS21495	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B4067_RS21500	COG4974	Belongs to the 'phage' integrase family
B4067_RS21505	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B4067_RS21510	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B4067_RS21515	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B4067_RS21520	COG1815	bacterial-type flagellum-dependent cell motility
B4067_RS21525	COG1558	bacterial-type flagellum-dependent cell motility
B4067_RS21530	COG1677	Flagellar hook-basal body complex protein FliE
B4067_RS21535	COG1766	The M ring may be actively involved in energy transduction
B4067_RS21540	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B4067_RS21545	COG1317	bacterial-type flagellum organization
B4067_RS21550	COG1157	protein secretion by the type III secretion system
B4067_RS21555	COG2882	bacterial-type flagellum organization
B4067_RS21560	COG3334	PFAM MgtE intracellular
B4067_RS21565	COG3144	bacterial-type flagellum assembly
B4067_RS21570	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B4067_RS21575	COG4786	Flagellar basal body rod
B4067_RS21580	COG1582	Flagellar protein (FlbD)
B4067_RS21585	COG1580	Controls the rotational direction of flagella during chemotaxis
B4067_RS21590	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B4067_RS21595	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B4067_RS21595	COG1776	CheC inhibitor of MCP methylation
B4067_RS21600	COG2201	protein-glutamate methylesterase activity
B4067_RS21605	COG3190	flagellar
B4067_RS21610	COG1338	Plays a role in the flagellum-specific transport system
B4067_RS21615	COG1987	bacterial-type flagellum assembly
B4067_RS21620	COG1684	flagellar biosynthetic protein fliR
B4067_RS21625	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B4067_RS21630	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B4067_RS21635	COG1419	protein localization to endoplasmic reticulum
B4067_RS21640	COG0455	bacterial-type flagellum organization
B4067_RS21645	COG2201	protein-glutamate methylesterase activity
B4067_RS21650	COG0643	Histidine kinase
B4067_RS21650	COG2198	Histidine kinase
B4067_RS21655	COG0835	chemotaxis
B4067_RS21660	COG1776	CheC inhibitor of MCP methylation
B4067_RS21665	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
B4067_RS21670	COG1191	sigma factor activity
B4067_RS21680	COG0052	Belongs to the universal ribosomal protein uS2 family
B4067_RS21685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B4067_RS21690	COG0528	UMP kinase activity
B4067_RS21695	COG0233	cytoplasmic translational termination
B4067_RS21700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B4067_RS21705	COG4589	Belongs to the CDS family
B4067_RS21710	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B4067_RS21715	COG0750	zinc metalloprotease
B4067_RS21720	COG0442	prolyl-tRNA aminoacylation
B4067_RS21725	COG2176	DNA-directed DNA polymerase activity
B4067_RS21730	COG0779	Required for maturation of 30S ribosomal subunits
B4067_RS21735	COG0195	Participates in both transcription termination and antitermination
B4067_RS21740	COG2740	Nucleic-acid-binding protein implicated in transcription termination
B4067_RS21745	COG1358	cellular component organization or biogenesis
B4067_RS21750	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B4067_RS21755	COG1550	Protein conserved in bacteria
B4067_RS21760	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B4067_RS21765	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B4067_RS21770	COG0196	riboflavin kinase activity
B4067_RS21775	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B4067_RS21780	COG1185	polyribonucleotide nucleotidyltransferase activity
B4067_RS21785	COG0726	polysaccharide deacetylase
B4067_RS21790	COG0612	Peptidase, M16
B4067_RS21795	COG1873	PFAM PRC-barrel domain
B4067_RS21805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B4067_RS21810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B4067_RS21815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B4067_RS21820	COG0527	aspartate kinase activity
B4067_RS21825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B4067_RS21830	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B4067_RS21835	COG0740	serine-type endopeptidase activity
B4067_RS21845	COG1674	ftsk spoiiie
B4067_RS21845	COG4980	gas vesicle protein
B4067_RS21850	COG2188	Transcriptional regulator
B4067_RS21855	COG2814	Major facilitator Superfamily
B4067_RS21860	COG0612	Peptidase, M16
B4067_RS21865	COG0612	Peptidase, M16
B4067_RS21870	COG0300	oxidoreductase activity
B4067_RS21885	COG1426	Protein conserved in bacteria
B4067_RS21890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B4067_RS21895	COG1058	Belongs to the CinA family
B4067_RS21895	COG1546	Belongs to the CinA family
B4067_RS21900	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B4067_RS21905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B4067_RS21910	COG1418	mRNA catabolic process
B4067_RS21915	COG1692	metallophosphoesterase
B4067_RS21920	COG2359	stage V sporulation protein S
B4067_RS21925	COG1063	alcohol dehydrogenase
B4067_RS21930	COG0156	8-amino-7-oxononanoate synthase activity
B4067_RS21935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B4067_RS21940	COG4550	Control of competence regulator ComK, YlbF/YmcA
B4067_RS21950	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B4067_RS21955	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B4067_RS21975	COG3226	Transcriptional regulator
B4067_RS21985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4067_RS21990	COG1404	Belongs to the peptidase S8 family
B4067_RS22000	COG4195	phage-related replication protein
B4067_RS22005	COG1764	response to oxidative stress
B4067_RS22010	COG2076	Multidrug Resistance protein
B4067_RS22015	COG2076	Multidrug Resistance protein
B4067_RS22030	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B4067_RS22035	COG1923	regulation of RNA biosynthetic process
B4067_RS22050	COG1780	Probably involved in ribonucleotide reductase function
B4067_RS22055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B4067_RS22060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B4067_RS22065	COG4112	unkown
B4067_RS22070	COG0860	N-Acetylmuramoyl-L-alanine amidase
B4067_RS22075	COG0464	growth
B4067_RS22085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B4067_RS22090	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
B4067_RS22095	COG0789	Transcriptional regulator
B4067_RS22100	COG0174	glutamine synthetase
B4067_RS22115	COG5444	nuclease activity
B4067_RS22145	COG4282	regulation of fungal-type cell wall biogenesis
B4067_RS22175	COG4585	Histidine kinase
B4067_RS22185	COG0142	geranyltranstransferase activity
B4067_RS22200	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
B4067_RS22205	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B4067_RS22210	COG1335	isochorismatase
B4067_RS22215	COG5506	Protein of unknown function (DUF1694)
B4067_RS22230	COG0628	permease
B4067_RS22245	COG1418	mRNA catabolic process
B4067_RS22250	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS22260	COG1511	domain protein
B4067_RS22265	COG0433	COG0433 Predicted ATPase
B4067_RS22265	COG1674	ftsk spoiiie
B4067_RS22270	COG4499	WXG100 protein secretion system (Wss), protein YukC
B4067_RS22275	COG5417	Belongs to the EsaB family
B4067_RS22280	COG4842	Belongs to the WXG100 family
B4067_RS22285	COG2508	Transcriptional regulator
B4067_RS22285	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B4067_RS22290	COG0686	Belongs to the AlaDH PNT family
B4067_RS22295	COG5634	Uncharacterized conserved protein (DUF2278)
B4067_RS22300	COG3251	PFAM MbtH domain protein
B4067_RS22305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B4067_RS22310	COG3433	isochorismatase activity
B4067_RS22310	COG1535	isochorismatase
B4067_RS22315	COG1021	2,3-dihydroxybenzoate-AMP ligase
B4067_RS22320	COG1169	isochorismate synthase
B4067_RS22325	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS22330	COG2819	hydrolase of the alpha beta superfamily
B4067_RS22335	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B4067_RS22340	COG1268	BioY protein
B4067_RS22345	COG2056	Na+-H+ antiporter family
B4067_RS22350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B4067_RS22355	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
B4067_RS22360	COG3584	3D domain protein
B4067_RS22375	COG1252	NADH dehydrogenase
B4067_RS22380	COG0492	ferredoxin-NADP+ reductase activity
B4067_RS22390	COG0516	GMP reductase activity
B4067_RS22395	COG2808	Putative FMN-binding domain
B4067_RS22400	COG0456	acetyltransferase
B4067_RS22405	COG0316	Belongs to the HesB IscA family
B4067_RS22410	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B4067_RS22415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B4067_RS22420	COG4844	belongs to the
B4067_RS22425	COG1252	NADH dehydrogenase
B4067_RS22430	COG4837	Protein of unknown function (DUF1462)
B4067_RS22435	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B4067_RS22440	COG1506	peptidase
B4067_RS22440	COG4946	Tricorn protease homolog
B4067_RS22440	COG0823	Involved in the tonB-independent uptake of proteins
B4067_RS22445	COG0083	homoserine kinase activity
B4067_RS22450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B4067_RS22455	COG0460	homoserine dehydrogenase
B4067_RS22460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B4067_RS22465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B4067_RS22470	COG0647	UMP catabolic process
B4067_RS22475	COG2445	Protein of unknown function DUF86
B4067_RS22480	COG4470	Protein conserved in bacteria
B4067_RS22490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B4067_RS22495	COG0739	heme binding
B4067_RS22505	COG3377	Domain of unknown function (DUF1805)
B4067_RS22510	COG0737	Belongs to the 5'-nucleotidase family
B4067_RS22515	COG0730	response to heat
B4067_RS22520	COG1801	Protein of unknown function DUF72
B4067_RS22530	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B4067_RS22535	COG2508	Transcriptional regulator
B4067_RS22540	COG2233	PERMEase
B4067_RS22545	COG2233	PERMEase
B4067_RS22550	COG3195	allantoin biosynthetic process
B4067_RS22550	COG3648	Uricase
B4067_RS22555	COG2351	hydroxyisourate hydrolase activity
B4067_RS22565	COG2080	2 iron, 2 sulfur cluster binding
B4067_RS22570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B4067_RS22575	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B4067_RS22580	COG2068	MobA-Related Protein
B4067_RS22585	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B4067_RS22605	COG0561	phosphatase activity
B4067_RS22610	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B4067_RS22615	COG1914	H( )-stimulated, divalent metal cation uptake system
B4067_RS22620	COG4336	lyase activity
B4067_RS22625	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B4067_RS22630	COG1984	allophanate hydrolase subunit 2
B4067_RS22635	COG1414	Transcriptional regulator
B4067_RS22640	COG2755	lipolytic protein G-D-S-L family
B4067_RS22650	COG2329	Antibiotic biosynthesis monooxygenase
B4067_RS22655	COG0768	penicillin binding
B4067_RS22660	COG4989	oxidoreductase activity
B4067_RS22665	COG3711	transcriptional antiterminator
B4067_RS22670	COG0318	PFAM AMP-dependent synthetase and ligase
B4067_RS22675	COG2226	methyltransferase
B4067_RS22680	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS22685	COG1917	Cupin 2, conserved barrel domain protein
B4067_RS22690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4067_RS22695	COG3871	stress protein (general stress protein 26)
B4067_RS22705	COG2814	Major facilitator Superfamily
B4067_RS22710	COG1522	sequence-specific DNA binding
B4067_RS22715	COG0551	DNA topoisomerase type I activity
B4067_RS22715	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B4067_RS22720	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B4067_RS22735	COG1215	transferase activity, transferring glycosyl groups
B4067_RS22745	COG0531	amino acid
B4067_RS22750	COG0494	nUDIX hydrolase
B4067_RS22770	COG1914	H( )-stimulated, divalent metal cation uptake system
B4067_RS22775	COG2261	transglycosylase associated protein
B4067_RS22780	COG4876	unkown
B4067_RS22785	COG2217	Heavy metal translocating P-type atpase
B4067_RS22790	COG3729	General stress protein
B4067_RS22795	COG0662	Cupin 2, conserved barrel domain protein
B4067_RS22800	COG2329	Antibiotic biosynthesis monooxygenase
B4067_RS22810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B4067_RS22815	COG3290	protein histidine kinase activity
B4067_RS22820	COG4565	transcriptional regulatory protein
B4067_RS22825	COG1301	dicarboxylic acid transport
B4067_RS22830	COG0628	permease
B4067_RS22840	COG1131	(ABC) transporter
B4067_RS22845	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B4067_RS22855	COG1960	acyl-CoA dehydrogenase activity
B4067_RS22885	COG0860	N-Acetylmuramoyl-L-alanine amidase
B4067_RS22910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B4067_RS22915	COG0412	Dienelactone hydrolase
B4067_RS22925	COG0473	3-isopropylmalate dehydrogenase activity
B4067_RS22930	COG0246	Mannitol dehydrogenase
B4067_RS22935	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B4067_RS22940	COG2213	PTS system mannitol-specific
B4067_RS22950	COG1349	DNA-binding transcription factor activity
B4067_RS22955	COG2372	response to copper ion
B4067_RS22955	COG1276	copper resistance
B4067_RS22960	COG4549	nuclear export factor GLE1
B4067_RS22965	COG1028	Short-chain dehydrogenase reductase Sdr
B4067_RS22970	COG4975	Glucose uptake
B4067_RS22975	COG1012	belongs to the aldehyde dehydrogenase family
B4067_RS22980	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B4067_RS22985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4067_RS22990	COG0640	Transcriptional regulator
B4067_RS22995	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B4067_RS23000	COG0778	Nitroreductase
B4067_RS23005	COG1309	transcriptional regulator
B4067_RS23010	COG2814	Major facilitator Superfamily
B4067_RS23015	COG4607	ABC-type enterochelin transport system periplasmic component
B4067_RS23020	COG4604	ABC transporter, ATP-binding protein
B4067_RS23025	COG4605	iron ion homeostasis
B4067_RS23030	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4067_RS23035	COG0527	aspartate kinase activity
B4067_RS23055	COG0457	Tetratricopeptide repeat
B4067_RS23060	COG5002	protein histidine kinase activity
B4067_RS23060	COG3850	Histidine kinase
B4067_RS23065	COG0745	RESPONSE REGULATOR receiver
B4067_RS23070	COG0577	efflux transmembrane transporter activity
B4067_RS23075	COG1136	(ABC) transporter
B4067_RS23080	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B4067_RS23090	COG0697	spore germination
B4067_RS23100	COG5434	Belongs to the glycosyl hydrolase 28 family
B4067_RS23105	COG3104	oligopeptide transport
B4067_RS23110	COG0596	Alpha beta hydrolase
B4067_RS23125	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B4067_RS23130	COG0163	prenyltransferase activity
B4067_RS23135	COG0583	DNA-binding transcription factor activity
B4067_RS23140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B4067_RS23145	COG0765	amino acid transport
B4067_RS23150	COG1126	abc transporter atp-binding protein
B4067_RS23155	COG2364	Membrane
B4067_RS23165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4067_RS23170	COG0697	spore germination
B4067_RS23180	COG2814	Major facilitator Superfamily
B4067_RS23185	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B4067_RS23190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B4067_RS23195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B4067_RS23200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B4067_RS23205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B4067_RS23215	COG1733	regulation of RNA biosynthetic process
B4067_RS23220	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
B4067_RS23225	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B4067_RS23230	COG0840	transmembrane signaling receptor activity
B4067_RS23230	COG3290	protein histidine kinase activity
B4067_RS23235	COG3209	COG3209 Rhs family protein
B4067_RS23245	COG2723	6-phospho-beta-galactosidase activity
B4067_RS23255	COG1714	RDD family
B4067_RS23265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B4067_RS23270	COG0765	amino acid transport
B4067_RS23275	COG0523	cobalamin synthesis protein
B4067_RS23285	COG1376	ErfK ybiS ycfS ynhG family protein
B4067_RS23295	COG2223	nitrite transmembrane transporter activity
B4067_RS23300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B4067_RS23305	COG0243	molybdopterin cofactor binding
B4067_RS23310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B4067_RS23315	COG2146	nitrite reductase [NAD(P)H] activity
B4067_RS23320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B4067_RS23320	COG1587	Uroporphyrinogen-III synthase
B4067_RS23325	COG0492	ferredoxin-NADP+ reductase activity
B4067_RS23330	COG2267	carboxylic ester hydrolase activity
B4067_RS23335	COG0701	Predicted permease
B4067_RS23340	COG3689	TIGRFAM TIGR03943 family protein
B4067_RS23345	COG2508	Transcriptional regulator
B4067_RS23350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B4067_RS23355	COG1012	belongs to the aldehyde dehydrogenase family
B4067_RS23360	COG0506	proline dehydrogenase activity
B4067_RS23365	COG3541	Predicted nucleotidyltransferase
B4067_RS23370	COG3458	cephalosporin-C deacetylase activity
B4067_RS23375	COG0583	DNA-binding transcription factor activity
B4067_RS23380	COG2226	methyltransferase
B4067_RS23385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B4067_RS23395	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B4067_RS23415	COG1280	lysine exporter protein (LysE YggA)
B4067_RS23420	COG1846	Transcriptional regulator
B4067_RS23425	COG2814	Major facilitator Superfamily
B4067_RS23430	COG1620	l-lactate permease
B4067_RS23435	COG0039	L-malate dehydrogenase activity
B4067_RS23440	COG0366	Alpha amylase catalytic
B4067_RS23455	COG1288	antiporter activity
B4067_RS23460	COG1473	amidohydrolase
B4067_RS23465	COG2113	Glycine betaine
B4067_RS23470	COG4176	ABC-type proline glycine betaine transport system permease component
B4067_RS23475	COG0517	IMP dehydrogenase activity
B4067_RS23475	COG4175	Glycine betaine
B4067_RS23480	COG0640	Transcriptional regulator
B4067_RS23485	COG2814	Major facilitator Superfamily
B4067_RS23585	COG1682	transport, permease protein
B4067_RS23620	COG0457	Tetratricopeptide repeat