locus-tag	class	description
AWM80_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWM80_RS00010	COG0592	DNA-directed DNA polymerase activity
AWM80_RS00015	COG2501	S4 domain
AWM80_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AWM80_RS00030	COG0187	DNA topoisomerase II activity
AWM80_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWM80_RS00070	COG0517	IMP dehydrogenase activity
AWM80_RS00070	COG0516	GMP reductase activity
AWM80_RS00075	COG1686	Belongs to the peptidase S11 family
AWM80_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AWM80_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AWM80_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AWM80_RS00100	COG1428	Deoxynucleoside kinase
AWM80_RS00105	COG1428	Deoxynucleoside kinase
AWM80_RS00110	COG1388	LysM domain
AWM80_RS00110	COG3858	chitin binding
AWM80_RS00115	COG1335	isochorismatase
AWM80_RS00120	COG0590	tRNA wobble adenosine to inosine editing
AWM80_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWM80_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AWM80_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AWM80_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AWM80_RS00190	COG3853	Toxic anion resistance protein (TelA)
AWM80_RS00195	COG1982	Orn Lys Arg decarboxylase major
AWM80_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AWM80_RS00205	COG3870	Protein conserved in bacteria
AWM80_RS00210	COG1728	Protein conserved in bacteria
AWM80_RS00215	COG0470	DNA polymerase III
AWM80_RS00220	COG1774	PSP1 C-terminal conserved region
AWM80_RS00225	COG4467	Involved in initiation control of chromosome replication
AWM80_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AWM80_RS00235	COG2827	Endonuclease containing a URI domain
AWM80_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AWM80_RS00245	COG2002	toxin-antitoxin pair type II binding
AWM80_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWM80_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWM80_RS00255	COG0084	hydrolase, TatD family'
AWM80_RS00260	COG3583	domain protein
AWM80_RS00260	COG3584	3D domain protein
AWM80_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AWM80_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AWM80_RS00280	COG4466	Protein conserved in bacteria
AWM80_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AWM80_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWM80_RS00300	COG0251	oxidation-reduction process
AWM80_RS00305	COG2088	sporulation resulting in formation of a cellular spore
AWM80_RS00315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AWM80_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWM80_RS00325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AWM80_RS00330	COG0193	aminoacyl-tRNA hydrolase activity
AWM80_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AWM80_RS00345	COG2002	toxin-antitoxin pair type II binding
AWM80_RS00350	COG2244	polysaccharide biosynthetic process
AWM80_RS00355	COG3956	TIGRFAM MazG family protein
AWM80_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AWM80_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AWM80_RS00380	COG1098	S1 RNA binding domain
AWM80_RS00395	COG2208	phosphoserine phosphatase activity
AWM80_RS00400	COG2304	oxidoreductase activity
AWM80_RS00405	COG0515	serine threonine protein kinase
AWM80_RS00410	COG0037	tRNA processing
AWM80_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AWM80_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWM80_RS00425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AWM80_RS00430	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AWM80_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWM80_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWM80_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWM80_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
AWM80_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWM80_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AWM80_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AWM80_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWM80_RS00475	COG1396	sequence-specific DNA binding
AWM80_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWM80_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AWM80_RS00570	COG4463	regulation of RNA biosynthetic process
AWM80_RS00575	COG3880	PFAM UvrB UvrC protein
AWM80_RS00580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AWM80_RS00585	COG0542	response to heat
AWM80_RS00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AWM80_RS00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AWM80_RS00600	COG4956	integral membrane protein (PIN domain superfamily)
AWM80_RS00605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AWM80_RS00610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AWM80_RS00615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWM80_RS00625	COG1045	serine acetyltransferase
AWM80_RS00630	COG0215	cysteine-tRNA ligase activity
AWM80_RS00635	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWM80_RS00640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWM80_RS00645	COG3688	RNA-binding protein containing a PIN domain
AWM80_RS00650	COG1595	DNA-templated transcription, initiation
AWM80_RS00660	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWM80_RS00665	COG0250	Participates in transcription elongation, termination and antitermination
AWM80_RS00675	COG0081	regulation of translation
AWM80_RS00680	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AWM80_RS00690	COG2813	Specifically methylates the guanine in position
AWM80_RS00695	COG0085	RNA polymerase activity
AWM80_RS00700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWM80_RS00705	COG1358	cellular component organization or biogenesis
AWM80_RS00710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AWM80_RS00715	COG0049	tRNA binding
AWM80_RS00720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWM80_RS00725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AWM80_RS00730	COG0596	Alpha beta hydrolase
AWM80_RS00740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AWM80_RS00745	COG0088	Forms part of the polypeptide exit tunnel
AWM80_RS00755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWM80_RS00770	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AWM80_RS00775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AWM80_RS00785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AWM80_RS00790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AWM80_RS00800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWM80_RS00810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AWM80_RS00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AWM80_RS00820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AWM80_RS00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AWM80_RS00835	COG0200	Binds to the 23S rRNA
AWM80_RS00840	COG0201	protein transport
AWM80_RS00845	COG0563	adenylate kinase activity
AWM80_RS00850	COG0024	Methionine aminopeptidase
AWM80_RS00855	COG2163	COG2163 Ribosomal protein L14E L6E L27E
AWM80_RS00865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AWM80_RS00870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AWM80_RS00875	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AWM80_RS00880	COG0202	RNA polymerase activity
AWM80_RS00885	COG0203	ribosomal protein L17
AWM80_RS00890	COG1122	ATPase activity
AWM80_RS00895	COG1122	ATPase activity
AWM80_RS00900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AWM80_RS00905	COG0101	tRNA pseudouridine synthase activity
AWM80_RS00910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AWM80_RS00915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AWM80_RS00920	COG2226	methyltransferase
AWM80_RS00930	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWM80_RS00935	COG0489	protein tyrosine kinase activity
AWM80_RS00945	COG2194	sulfuric ester hydrolase activity
AWM80_RS00950	COG0726	polysaccharide deacetylase
AWM80_RS01035	COG0659	secondary active sulfate transmembrane transporter activity
AWM80_RS01040	COG0385	Bile acid
AWM80_RS01045	COG2819	hydrolase of the alpha beta superfamily
AWM80_RS01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWM80_RS01055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWM80_RS01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWM80_RS01065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWM80_RS01065	COG2207	Transcriptional regulator
AWM80_RS01070	COG3876	Protein conserved in bacteria
AWM80_RS01075	COG1472	Belongs to the glycosyl hydrolase 3 family
AWM80_RS01080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AWM80_RS01085	COG1263	PTS System
AWM80_RS01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWM80_RS01090	COG1737	Transcriptional regulator
AWM80_RS01095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWM80_RS01100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWM80_RS01105	COG1683	Conserved Protein
AWM80_RS01135	COG1595	DNA-templated transcription, initiation
AWM80_RS01140	COG5662	AntiSigma factor
AWM80_RS01145	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AWM80_RS01150	COG4856	YbbR-like protein
AWM80_RS01155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWM80_RS01160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AWM80_RS01165	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AWM80_RS01170	COG2169	Transcriptional regulator
AWM80_RS01175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AWM80_RS01180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWM80_RS01185	COG3002	Belongs to the UPF0753 family
AWM80_RS01190	COG0288	reversible hydration of carbon dioxide
AWM80_RS01200	COG5609	conserved protein (DUF2294)
AWM80_RS01210	COG0640	Transcriptional regulator
AWM80_RS01215	COG2814	Major facilitator Superfamily
AWM80_RS01220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AWM80_RS01230	COG0535	radical SAM domain protein
AWM80_RS01235	COG1266	CAAX protease self-immunity
AWM80_RS01240	COG1131	(ABC) transporter
AWM80_RS01250	COG1413	lyase activity
AWM80_RS01255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWM80_RS01260	COG0596	Alpha beta hydrolase
AWM80_RS01265	COG0745	RESPONSE REGULATOR receiver
AWM80_RS01270	COG0642	Histidine kinase
AWM80_RS01280	COG0515	serine threonine protein kinase
AWM80_RS01295	COG1113	amino acid transport
AWM80_RS01310	COG2602	Beta-lactamase
AWM80_RS01315	COG2124	cytochrome p450
AWM80_RS01325	COG0531	amino acid
AWM80_RS01330	COG0584	glycerophosphoryl diester phosphodiesterase
AWM80_RS01335	COG2271	Major facilitator Superfamily
AWM80_RS01345	COG0456	acetyltransferase
AWM80_RS01345	COG1846	Transcriptional regulator
AWM80_RS01350	COG2271	Major facilitator Superfamily
AWM80_RS01365	COG3409	Peptidoglycan-binding domain 1 protein
AWM80_RS01370	COG0697	spore germination
AWM80_RS01375	COG1917	Cupin 2, conserved barrel domain protein
AWM80_RS01375	COG2207	Transcriptional regulator
AWM80_RS01380	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AWM80_RS01385	COG3591	Belongs to the peptidase S1B family
AWM80_RS01395	COG0596	Alpha beta hydrolase
AWM80_RS01400	COG1183	phosphatidylcholine synthase activity
AWM80_RS01405	COG0586	Pfam SNARE associated Golgi protein
AWM80_RS01410	COG0688	phosphatidylethanolamine metabolic process
AWM80_RS01420	COG2312	Erythromycin esterase
AWM80_RS01425	COG2207	Transcriptional regulator
AWM80_RS01430	COG1054	Belongs to the UPF0176 family
AWM80_RS01435	COG1301	dicarboxylic acid transport
AWM80_RS01440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWM80_RS01440	COG1263	PTS System
AWM80_RS01440	COG2190	(PTS) system
AWM80_RS01445	COG0363	glucosamine-6-phosphate deaminase activity
AWM80_RS01450	COG2188	Transcriptional regulator
AWM80_RS01460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWM80_RS01465	COG0833	amino acid
AWM80_RS01470	COG2040	homocysteine
AWM80_RS01480	COG1115	amino acid carrier protein
AWM80_RS01485	COG2066	Belongs to the glutaminase family
AWM80_RS01490	COG4191	Histidine kinase
AWM80_RS01495	COG0784	Response regulator, receiver
AWM80_RS01500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWM80_RS01505	COG1012	belongs to the aldehyde dehydrogenase family
AWM80_RS01510	COG2271	Major facilitator Superfamily
AWM80_RS01515	COG4948	Mandelate Racemase Muconate Lactonizing
AWM80_RS01520	COG2186	Transcriptional regulator
AWM80_RS01525	COG2721	sulfolactate sulfo-lyase activity
AWM80_RS01530	COG3173	Aminoglycoside phosphotransferase
AWM80_RS01540	COG0697	spore germination
AWM80_RS01545	COG0745	RESPONSE REGULATOR receiver
AWM80_RS01550	COG2205	protein histidine kinase activity
AWM80_RS01555	COG1131	(ABC) transporter
AWM80_RS01575	COG3773	Cell wall hydrolase
AWM80_RS01580	COG2304	oxidoreductase activity
AWM80_RS01590	COG3540	Alkaline phosphatase
AWM80_RS01595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWM80_RS01600	COG0805	protein transport
AWM80_RS01605	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AWM80_RS01610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWM80_RS01615	COG0477	Major facilitator Superfamily
AWM80_RS01620	COG1309	transcriptional regulator
AWM80_RS01625	COG0252	asparaginase activity
AWM80_RS01630	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AWM80_RS01635	COG1714	RDD family
AWM80_RS01640	COG3012	SEC-C Motif Domain Protein
AWM80_RS01640	COG1405	negative regulation of cell septum assembly
AWM80_RS01645	COG3290	protein histidine kinase activity
AWM80_RS01650	COG3279	Response regulator of the LytR AlgR family
AWM80_RS01655	COG4555	ABC transporter
AWM80_RS01660	COG1668	transmembrane transport
AWM80_RS01665	COG0667	Aldo Keto reductase
AWM80_RS01675	COG1595	DNA-templated transcription, initiation
AWM80_RS01680	COG1595	DNA-templated transcription, initiation
AWM80_RS01685	COG1876	peptidase activity
AWM80_RS01690	COG0457	Tetratricopeptide repeat
AWM80_RS01695	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS01700	COG0366	Alpha amylase catalytic
AWM80_RS01705	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWM80_RS01710	COG1121	(ABC) transporter
AWM80_RS01715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWM80_RS01720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWM80_RS01725	COG2310	stress, protein
AWM80_RS01730	COG2310	stress, protein
AWM80_RS01735	COG2310	stress, protein
AWM80_RS01740	COG0861	Integral membrane protein TerC family
AWM80_RS01750	COG3853	Toxic anion resistance protein (TelA)
AWM80_RS01755	COG0477	Major facilitator Superfamily
AWM80_RS01760	COG2814	Major facilitator Superfamily
AWM80_RS01765	COG0640	Transcriptional regulator
AWM80_RS01770	COG4175	Glycine betaine
AWM80_RS01770	COG0517	IMP dehydrogenase activity
AWM80_RS01775	COG4176	ABC-type proline glycine betaine transport system permease component
AWM80_RS01780	COG2113	Glycine betaine
AWM80_RS01785	COG1473	amidohydrolase
AWM80_RS01790	COG1288	antiporter activity
AWM80_RS01805	COG0366	Alpha amylase catalytic
AWM80_RS01810	COG0039	L-malate dehydrogenase activity
AWM80_RS01815	COG1620	l-lactate permease
AWM80_RS01820	COG2814	Major facilitator Superfamily
AWM80_RS01825	COG1846	Transcriptional regulator
AWM80_RS01830	COG1280	lysine exporter protein (LysE YggA)
AWM80_RS01835	COG3403	YqcI/YcgG family
AWM80_RS01840	COG1113	amino acid transport
AWM80_RS01845	COG3665	Urea carboxylase-associated protein
AWM80_RS01850	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AWM80_RS01855	COG1660	Displays ATPase and GTPase activities
AWM80_RS01860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AWM80_RS01865	COG2226	methyltransferase
AWM80_RS01870	COG0583	DNA-binding transcription factor activity
AWM80_RS01875	COG3458	cephalosporin-C deacetylase activity
AWM80_RS01880	COG3541	Predicted nucleotidyltransferase
AWM80_RS01885	COG0506	proline dehydrogenase activity
AWM80_RS01890	COG1012	belongs to the aldehyde dehydrogenase family
AWM80_RS01895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWM80_RS01900	COG2508	Transcriptional regulator
AWM80_RS01905	COG3689	TIGRFAM TIGR03943 family protein
AWM80_RS01910	COG0701	Predicted permease
AWM80_RS01915	COG2267	carboxylic ester hydrolase activity
AWM80_RS01920	COG0492	ferredoxin-NADP+ reductase activity
AWM80_RS01925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWM80_RS01925	COG1587	Uroporphyrinogen-III synthase
AWM80_RS01930	COG2146	nitrite reductase [NAD(P)H] activity
AWM80_RS01935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWM80_RS01940	COG0243	molybdopterin cofactor binding
AWM80_RS01945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWM80_RS01950	COG2223	nitrite transmembrane transporter activity
AWM80_RS01955	COG1469	GTP cyclohydrolase I activity
AWM80_RS01960	COG1376	ErfK ybiS ycfS ynhG family protein
AWM80_RS01970	COG0523	cobalamin synthesis protein
AWM80_RS01975	COG0765	amino acid transport
AWM80_RS01980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWM80_RS01990	COG1714	RDD family
AWM80_RS02000	COG2723	6-phospho-beta-galactosidase activity
AWM80_RS02010	COG3209	COG3209 Rhs family protein
AWM80_RS02015	COG0840	transmembrane signaling receptor activity
AWM80_RS02015	COG3290	protein histidine kinase activity
AWM80_RS02020	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AWM80_RS02025	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AWM80_RS02030	COG1733	regulation of RNA biosynthetic process
AWM80_RS02040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWM80_RS02045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWM80_RS02050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWM80_RS02055	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AWM80_RS02060	COG2814	Major facilitator Superfamily
AWM80_RS02070	COG0697	spore germination
AWM80_RS02075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWM80_RS02085	COG2364	Membrane
AWM80_RS02090	COG1126	abc transporter atp-binding protein
AWM80_RS02095	COG0765	amino acid transport
AWM80_RS02100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWM80_RS02105	COG0583	DNA-binding transcription factor activity
AWM80_RS02110	COG0163	prenyltransferase activity
AWM80_RS02115	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AWM80_RS02130	COG0596	Alpha beta hydrolase
AWM80_RS02135	COG3104	oligopeptide transport
AWM80_RS02140	COG5434	Belongs to the glycosyl hydrolase 28 family
AWM80_RS02150	COG0697	spore germination
AWM80_RS02160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AWM80_RS02165	COG1136	(ABC) transporter
AWM80_RS02170	COG0577	efflux transmembrane transporter activity
AWM80_RS02175	COG0745	RESPONSE REGULATOR receiver
AWM80_RS02180	COG3850	Histidine kinase
AWM80_RS02180	COG5002	protein histidine kinase activity
AWM80_RS02185	COG0457	Tetratricopeptide repeat
AWM80_RS02200	COG0527	aspartate kinase activity
AWM80_RS02205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWM80_RS02210	COG4605	iron ion homeostasis
AWM80_RS02215	COG4604	ABC transporter, ATP-binding protein
AWM80_RS02220	COG4607	ABC-type enterochelin transport system periplasmic component
AWM80_RS02225	COG2814	Major facilitator Superfamily
AWM80_RS02230	COG1309	transcriptional regulator
AWM80_RS02235	COG0778	Nitroreductase
AWM80_RS02240	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AWM80_RS02245	COG0640	Transcriptional regulator
AWM80_RS02250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWM80_RS02255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AWM80_RS02260	COG1012	belongs to the aldehyde dehydrogenase family
AWM80_RS02265	COG4975	Glucose uptake
AWM80_RS02270	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS02275	COG4549	nuclear export factor GLE1
AWM80_RS02280	COG1276	copper resistance
AWM80_RS02280	COG2372	response to copper ion
AWM80_RS02285	COG1349	DNA-binding transcription factor activity
AWM80_RS02295	COG2213	PTS system mannitol-specific
AWM80_RS02300	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWM80_RS02305	COG0246	Mannitol dehydrogenase
AWM80_RS02310	COG0473	3-isopropylmalate dehydrogenase activity
AWM80_RS02315	COG0681	Belongs to the peptidase S26 family
AWM80_RS02325	COG0412	Dienelactone hydrolase
AWM80_RS02330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWM80_RS02340	COG0561	phosphatase activity
AWM80_RS02345	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AWM80_RS02350	COG1914	H( )-stimulated, divalent metal cation uptake system
AWM80_RS02355	COG4336	lyase activity
AWM80_RS02360	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AWM80_RS02365	COG1984	allophanate hydrolase subunit 2
AWM80_RS02375	COG2755	lipolytic protein G-D-S-L family
AWM80_RS02385	COG2329	Antibiotic biosynthesis monooxygenase
AWM80_RS02390	COG0768	penicillin binding
AWM80_RS02395	COG4989	oxidoreductase activity
AWM80_RS02400	COG3711	transcriptional antiterminator
AWM80_RS02405	COG0318	PFAM AMP-dependent synthetase and ligase
AWM80_RS02410	COG2226	methyltransferase
AWM80_RS02415	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS02420	COG1917	Cupin 2, conserved barrel domain protein
AWM80_RS02425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWM80_RS02430	COG3871	stress protein (general stress protein 26)
AWM80_RS02440	COG2814	Major facilitator Superfamily
AWM80_RS02445	COG1522	sequence-specific DNA binding
AWM80_RS02450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWM80_RS02450	COG0551	DNA topoisomerase type I activity
AWM80_RS02455	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AWM80_RS02460	COG3706	GGDEF domain
AWM80_RS02465	COG5298	Protein conserved in bacteria
AWM80_RS02470	COG1215	transferase activity, transferring glycosyl groups
AWM80_RS02480	COG0531	amino acid
AWM80_RS02485	COG0494	nUDIX hydrolase
AWM80_RS02490	COG0028	Belongs to the TPP enzyme family
AWM80_RS02505	COG1914	H( )-stimulated, divalent metal cation uptake system
AWM80_RS02510	COG2261	transglycosylase associated protein
AWM80_RS02515	COG4876	unkown
AWM80_RS02520	COG2217	Heavy metal translocating P-type atpase
AWM80_RS02525	COG3729	General stress protein
AWM80_RS02530	COG0662	Cupin 2, conserved barrel domain protein
AWM80_RS02535	COG2329	Antibiotic biosynthesis monooxygenase
AWM80_RS02540	COG3546	catalase activity
AWM80_RS02545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AWM80_RS02550	COG3290	protein histidine kinase activity
AWM80_RS02555	COG4565	transcriptional regulatory protein
AWM80_RS02560	COG1301	dicarboxylic acid transport
AWM80_RS02565	COG0628	permease
AWM80_RS02575	COG1131	(ABC) transporter
AWM80_RS02580	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AWM80_RS02590	COG1960	acyl-CoA dehydrogenase activity
AWM80_RS02605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWM80_RS02610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWM80_RS02615	COG1181	Belongs to the D-alanine--D-alanine ligase family
AWM80_RS02620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWM80_RS02625	COG0513	Belongs to the DEAD box helicase family
AWM80_RS02630	COG3402	PFAM membrane-flanked domain
AWM80_RS02635	COG3428	Bacterial PH domain
AWM80_RS02640	COG0705	Rhomboid family
AWM80_RS02645	COG0736	holo-[acyl-carrier-protein] synthase activity
AWM80_RS02650	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AWM80_RS02655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AWM80_RS02660	COG0864	Transcriptional regulator
AWM80_RS02665	COG2337	Toxic component of a toxin-antitoxin (TA) module
AWM80_RS02670	COG1366	Belongs to the anti-sigma-factor antagonist family
AWM80_RS02675	COG1366	Belongs to the anti-sigma-factor antagonist family
AWM80_RS02680	COG2172	sigma factor antagonist activity
AWM80_RS02685	COG2208	phosphoserine phosphatase activity
AWM80_RS02690	COG1366	Belongs to the anti-sigma-factor antagonist family
AWM80_RS02695	COG2172	sigma factor antagonist activity
AWM80_RS02700	COG1191	sigma factor activity
AWM80_RS02705	COG2208	phosphoserine phosphatase activity
AWM80_RS02720	COG1673	EVE domain
AWM80_RS02725	COG1846	Transcriptional regulator
AWM80_RS02730	COG2183	response to ionizing radiation
AWM80_RS02740	COG3091	SprT-like family
AWM80_RS02775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWM80_RS02780	COG1522	sequence-specific DNA binding
AWM80_RS02785	COG1522	sequence-specific DNA binding
AWM80_RS02790	COG1335	isochorismatase
AWM80_RS02795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AWM80_RS02800	COG2814	Major facilitator Superfamily
AWM80_RS02820	COG0693	protein deglycase activity
AWM80_RS02825	COG1278	Cold shock
AWM80_RS02830	COG1329	Transcriptional regulator
AWM80_RS02835	COG0697	spore germination
AWM80_RS02840	COG1917	Cupin 2, conserved barrel domain protein
AWM80_RS02840	COG2207	Transcriptional regulator
AWM80_RS02845	COG0697	spore germination
AWM80_RS02850	COG2207	Transcriptional regulator
AWM80_RS02850	COG3708	Transcriptional regulator
AWM80_RS02855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWM80_RS02860	COG0477	Major facilitator Superfamily
AWM80_RS02870	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AWM80_RS02880	COG0697	spore germination
AWM80_RS02885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWM80_RS02890	COG2030	dehydratase
AWM80_RS02895	COG3545	Serine hydrolase
AWM80_RS02900	COG1733	regulation of RNA biosynthetic process
AWM80_RS02905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWM80_RS02910	COG1733	regulation of RNA biosynthetic process
AWM80_RS02915	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWM80_RS02920	COG2814	Major facilitator Superfamily
AWM80_RS02925	COG1309	transcriptional regulator
AWM80_RS02935	COG0640	Transcriptional regulator
AWM80_RS02940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AWM80_RS02950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWM80_RS02955	COG0697	spore germination
AWM80_RS02960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWM80_RS02965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWM80_RS02970	COG0640	Transcriptional regulator
AWM80_RS02975	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AWM80_RS02985	COG4585	Histidine kinase
AWM80_RS02990	COG2197	response regulator
AWM80_RS02995	COG2409	Drug exporters of the RND superfamily
AWM80_RS03000	COG0596	Alpha beta hydrolase
AWM80_RS03005	COG1811	Na channel or pump
AWM80_RS03010	COG4978	Transcriptional regulator
AWM80_RS03010	COG0789	Transcriptional regulator
AWM80_RS03015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWM80_RS03020	COG0778	Nitroreductase
AWM80_RS03025	COG0346	lactoylglutathione lyase activity
AWM80_RS03030	COG2259	Doxx family
AWM80_RS03035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWM80_RS03055	COG2323	membrane
AWM80_RS03060	COG2323	membrane
AWM80_RS03065	COG0071	Belongs to the small heat shock protein (HSP20) family
AWM80_RS03080	COG1309	transcriptional regulator
AWM80_RS03090	COG0456	acetyltransferase
AWM80_RS03095	COG0488	(ABC) transporter
AWM80_RS03100	COG1113	amino acid transport
AWM80_RS03105	COG2318	DinB family
AWM80_RS03110	COG1846	Transcriptional regulator
AWM80_RS03115	COG1033	growth of symbiont in host cell
AWM80_RS03115	COG2409	Drug exporters of the RND superfamily
AWM80_RS03120	COG0778	Nitroreductase
AWM80_RS03125	COG1846	Transcriptional regulator
AWM80_RS03130	COG2814	Major facilitator Superfamily
AWM80_RS03135	COG0730	response to heat
AWM80_RS03140	COG1802	Transcriptional regulator
AWM80_RS03145	COG1388	LysM domain
AWM80_RS03145	COG3858	chitin binding
AWM80_RS03150	COG1819	glycosyl
AWM80_RS03160	COG1785	Belongs to the alkaline phosphatase family
AWM80_RS03165	COG5646	InterPro IPR014922
AWM80_RS03175	COG0454	-acetyltransferase
AWM80_RS03180	COG1078	dGTPase activity
AWM80_RS03185	COG1388	LysM domain
AWM80_RS03190	COG2814	Major facilitator Superfamily
AWM80_RS03195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWM80_RS03200	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWM80_RS03205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWM80_RS03210	COG2723	6-phospho-beta-galactosidase activity
AWM80_RS03215	COG2188	Transcriptional regulator
AWM80_RS03220	COG1940	carbohydrate kinase activity
AWM80_RS03225	COG1482	cell wall glycoprotein biosynthetic process
AWM80_RS03230	COG4124	Belongs to the glycosyl hydrolase 26 family
AWM80_RS03275	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AWM80_RS03280	COG0802	atpase or kinase
AWM80_RS03285	COG1214	PFAM Peptidase M22, glycoprotease
AWM80_RS03290	COG0456	acetyltransferase
AWM80_RS03295	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AWM80_RS03300	COG0488	(ABC) transporter
AWM80_RS03305	COG0315	cyclic pyranopterin monophosphate synthase activity
AWM80_RS03310	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AWM80_RS03315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWM80_RS03320	COG0805	protein transport
AWM80_RS03330	COG1266	CAAX protease self-immunity
AWM80_RS03340	COG0459	protein refolding
AWM80_RS03355	COG3378	Phage plasmid primase P4 family
AWM80_RS03370	COG0270	DNA (cytosine-5-)-methyltransferase activity
AWM80_RS03375	COG0270	DNA (cytosine-5-)-methyltransferase activity
AWM80_RS03380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWM80_RS03400	COG1401	restriction endodeoxyribonuclease activity
AWM80_RS03415	COG1073	alpha beta
AWM80_RS03420	COG0457	Tetratricopeptide repeat
AWM80_RS03425	COG1063	alcohol dehydrogenase
AWM80_RS03430	COG2211	Major facilitator Superfamily
AWM80_RS03435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWM80_RS03440	COG1842	Phage shock protein A
AWM80_RS03445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWM80_RS03450	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AWM80_RS03455	COG4260	virion core protein, lumpy skin disease virus
AWM80_RS03465	COG2814	Major facilitator Superfamily
AWM80_RS03470	COG1063	alcohol dehydrogenase
AWM80_RS03475	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWM80_RS03480	COG0823	Involved in the tonB-independent uptake of proteins
AWM80_RS03495	COG2267	carboxylic ester hydrolase activity
AWM80_RS03505	COG2132	Multicopper oxidase
AWM80_RS03510	COG1113	amino acid transport
AWM80_RS03520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWM80_RS03525	COG0714	Associated with various cellular activities
AWM80_RS03530	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AWM80_RS03535	COG1305	Transglutaminase-like
AWM80_RS03540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AWM80_RS03540	COG0519	Catalyzes the synthesis of GMP from XMP
AWM80_RS03545	COG2252	PERMEase
AWM80_RS03550	COG3064	Membrane
AWM80_RS03560	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AWM80_RS03570	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AWM80_RS03575	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AWM80_RS03580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AWM80_RS03585	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AWM80_RS03590	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWM80_RS03595	COG0047	phosphoribosylformylglycinamidine synthase activity
AWM80_RS03600	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWM80_RS03605	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AWM80_RS03610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AWM80_RS03615	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AWM80_RS03620	COG0138	bifunctional purine biosynthesis protein purh
AWM80_RS03625	COG0151	Belongs to the GarS family
AWM80_RS03630	COG1522	sequence-specific DNA binding
AWM80_RS03635	COG0531	amino acid
AWM80_RS03645	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AWM80_RS03650	COG1470	cell adhesion involved in biofilm formation
AWM80_RS03655	COG4496	protein, YerC YecD
AWM80_RS03660	COG0069	glutamate synthase activity
AWM80_RS03670	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AWM80_RS03675	COG0210	DNA helicase
AWM80_RS03680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWM80_RS03685	COG4851	CamS sex pheromone cAM373 precursor
AWM80_RS03690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWM80_RS03695	COG1285	pathogenesis
AWM80_RS03700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWM80_RS03705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWM80_RS03710	COG0154	amidase activity
AWM80_RS03715	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWM80_RS03720	COG1309	transcriptional regulator
AWM80_RS03725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AWM80_RS03730	COG1597	lipid kinase activity
AWM80_RS03735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWM80_RS03740	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AWM80_RS03745	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AWM80_RS03750	COG1002	Type II restriction enzyme, methylase subunits
AWM80_RS03755	COG1061	Type III restriction enzyme res subunit
AWM80_RS03760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AWM80_RS03780	COG5444	nuclease activity
AWM80_RS03785	COG3391	amine dehydrogenase activity
AWM80_RS03790	COG0457	Tetratricopeptide repeat
AWM80_RS03800	COG0217	transcriptional regulatory protein
AWM80_RS03810	COG1309	transcriptional regulator
AWM80_RS03815	COG3631	Ketosteroid isomerase-related protein
AWM80_RS03820	COG0702	epimerase
AWM80_RS03835	COG3546	catalase activity
AWM80_RS03840	COG0454	-acetyltransferase
AWM80_RS03850	COG5578	integral membrane protein
AWM80_RS03855	COG2972	Histidine kinase
AWM80_RS03860	COG2207	Transcriptional regulator
AWM80_RS03860	COG4753	response regulator
AWM80_RS03865	COG1653	transport
AWM80_RS03870	COG1175	transmembrane transport
AWM80_RS03875	COG0395	ABC-type sugar transport system, permease component
AWM80_RS03880	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AWM80_RS03885	COG2207	Transcriptional regulator
AWM80_RS03890	COG2755	lipolytic protein G-D-S-L family
AWM80_RS03900	COG5578	integral membrane protein
AWM80_RS03905	COG3401	FG-GAP repeat protein
AWM80_RS03910	COG3401	FG-GAP repeat protein
AWM80_RS03915	COG2755	lipolytic protein G-D-S-L family
AWM80_RS03920	COG1874	Beta-galactosidase
AWM80_RS03930	COG1653	transport
AWM80_RS03935	COG4209	transmembrane transport
AWM80_RS03940	COG0395	ABC-type sugar transport system, permease component
AWM80_RS03945	COG1486	melibiose metabolic process
AWM80_RS03950	COG2323	membrane
AWM80_RS03955	COG2329	Antibiotic biosynthesis monooxygenase
AWM80_RS03960	COG0346	lactoylglutathione lyase activity
AWM80_RS03975	COG5583	Uncharacterized small protein (DUF2292)
AWM80_RS03980	COG0670	Belongs to the BI1 family
AWM80_RS03985	COG0697	spore germination
AWM80_RS03990	COG1846	Transcriptional regulator
AWM80_RS03995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWM80_RS04005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWM80_RS04005	COG2124	cytochrome p450
AWM80_RS04010	COG1368	sulfuric ester hydrolase activity
AWM80_RS04015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AWM80_RS04020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWM80_RS04025	COG1442	glycosyl transferase family 8
AWM80_RS04030	COG1216	Glycosyl transferase, family 2
AWM80_RS04035	COG1442	glycosyl transferase family 8
AWM80_RS04040	COG2223	nitrite transmembrane transporter activity
AWM80_RS04045	COG1011	Hydrolase
AWM80_RS04050	COG0531	amino acid
AWM80_RS04055	COG1012	belongs to the aldehyde dehydrogenase family
AWM80_RS04060	COG0840	transmembrane signaling receptor activity
AWM80_RS04065	COG0488	(ABC) transporter
AWM80_RS04075	COG0789	Transcriptional regulator
AWM80_RS04080	COG2814	Major facilitator Superfamily
AWM80_RS04095	COG0488	(ABC) transporter
AWM80_RS04100	COG0513	Belongs to the DEAD box helicase family
AWM80_RS04105	COG0456	acetyltransferase
AWM80_RS04110	COG2130	NADP-dependent
AWM80_RS04125	COG2211	Major facilitator Superfamily
AWM80_RS04130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AWM80_RS04135	COG1120	ATPase activity
AWM80_RS04140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWM80_RS04145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWM80_RS04150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AWM80_RS04165	COG3866	Pectate lyase
AWM80_RS04170	COG0471	metal ion transport
AWM80_RS04175	COG3290	protein histidine kinase activity
AWM80_RS04180	COG4565	transcriptional regulatory protein
AWM80_RS04185	COG3181	Tripartite tricarboxylate transporter family receptor
AWM80_RS04195	COG2851	Citrate transporter
AWM80_RS04200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWM80_RS04205	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AWM80_RS04210	COG1254	Belongs to the acylphosphatase family
AWM80_RS04215	COG2258	MOSC domain
AWM80_RS04235	COG0024	Methionine aminopeptidase
AWM80_RS04240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWM80_RS04240	COG1263	PTS System
AWM80_RS04245	COG1368	sulfuric ester hydrolase activity
AWM80_RS04255	COG1115	amino acid carrier protein
AWM80_RS04260	COG0531	amino acid
AWM80_RS04275	COG0697	spore germination
AWM80_RS04280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWM80_RS04280	COG1263	PTS System
AWM80_RS04285	COG0366	Alpha amylase catalytic
AWM80_RS04290	COG2188	Transcriptional regulator
AWM80_RS04295	COG0778	Nitroreductase
AWM80_RS04300	COG0737	Belongs to the 5'-nucleotidase family
AWM80_RS04305	COG0693	protein deglycase activity
AWM80_RS04310	COG2814	Major facilitator Superfamily
AWM80_RS04315	COG4840	Belongs to the UPF0435 family
AWM80_RS04320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWM80_RS04325	COG4980	gas vesicle protein
AWM80_RS04330	COG1295	ribonuclease BN
AWM80_RS04340	COG0477	Major facilitator Superfamily
AWM80_RS04350	COG0387	Pfam Sodium calcium exchanger
AWM80_RS04360	COG0668	transmembrane transport
AWM80_RS04365	COG0535	radical SAM domain protein
AWM80_RS04375	COG0726	polysaccharide deacetylase
AWM80_RS04380	COG2084	Dehydrogenase
AWM80_RS04385	COG0598	Magnesium transport protein CorA
AWM80_RS04390	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AWM80_RS04395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWM80_RS04405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWM80_RS04410	COG4637	Psort location Cytoplasmic, score
AWM80_RS04420	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWM80_RS04425	COG0022	dehydrogenase e1 component
AWM80_RS04430	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWM80_RS04435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWM80_RS04440	COG3284	Transcriptional regulator
AWM80_RS04450	COG1742	UPF0060 membrane protein
AWM80_RS04475	COG4842	Belongs to the WXG100 family
AWM80_RS04480	COG1486	melibiose metabolic process
AWM80_RS04485	COG1737	Transcriptional regulator
AWM80_RS04490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWM80_RS04490	COG1263	PTS System
AWM80_RS04495	COG1132	(ABC) transporter
AWM80_RS04500	COG1132	(ABC) transporter
AWM80_RS04505	COG2259	Doxx family
AWM80_RS04510	COG2514	catechol 2,3-dioxygenase activity
AWM80_RS04515	COG4977	sequence-specific DNA binding
AWM80_RS04515	COG1917	Cupin 2, conserved barrel domain protein
AWM80_RS04520	COG2814	Major facilitator Superfamily
AWM80_RS04525	COG1082	Xylose isomerase domain protein TIM barrel
AWM80_RS04530	COG0673	inositol 2-dehydrogenase activity
AWM80_RS04535	COG4585	Histidine kinase
AWM80_RS04540	COG2197	response regulator
AWM80_RS04545	COG1131	(ABC) transporter
AWM80_RS04550	COG0842	Transport permease protein
AWM80_RS04550	COG1511	domain protein
AWM80_RS04555	COG0842	Transport permease protein
AWM80_RS04560	COG1695	Transcriptional regulator
AWM80_RS04565	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AWM80_RS04570	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AWM80_RS04575	COG1309	transcriptional regulator
AWM80_RS04580	COG2814	Major facilitator Superfamily
AWM80_RS04585	COG2318	DinB family
AWM80_RS04590	COG2814	Major facilitator Superfamily
AWM80_RS04595	COG1846	Transcriptional regulator
AWM80_RS04600	COG0392	lysyltransferase activity
AWM80_RS04600	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AWM80_RS04605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWM80_RS04610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWM80_RS04615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWM80_RS04620	COG0384	phenazine biosynthesis protein PhzF
AWM80_RS04625	COG0778	Nitroreductase
AWM80_RS04640	COG1090	epimerase
AWM80_RS04645	COG2137	regulation of response to DNA damage stimulus
AWM80_RS04660	COG2814	Major facilitator Superfamily
AWM80_RS04675	COG3103	Sh3 type 3 domain protein
AWM80_RS04680	COG5658	integral membrane protein
AWM80_RS04685	COG0596	Alpha beta hydrolase
AWM80_RS04690	COG0463	Glycosyl transferase, family 2
AWM80_RS04695	COG4485	Bacterial membrane protein, YfhO
AWM80_RS04700	COG1988	membrane-bound metal-dependent
AWM80_RS04705	COG1194	a g-specific adenine glycosylase
AWM80_RS04715	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS04730	COG3557	Belongs to the UPF0374 family
AWM80_RS04735	COG1132	(ABC) transporter
AWM80_RS04740	COG4129	membrane
AWM80_RS04745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWM80_RS04750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AWM80_RS04755	COG0735	belongs to the Fur family
AWM80_RS04870	COG4326	sporulation control protein
AWM80_RS04880	COG5577	PFAM Coat F domain
AWM80_RS04885	COG3340	Belongs to the peptidase S51 family
AWM80_RS04890	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AWM80_RS04895	COG0277	FAD linked oxidase domain protein
AWM80_RS04905	COG0753	catalase activity
AWM80_RS04910	COG1116	anion transmembrane transporter activity
AWM80_RS04915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWM80_RS04920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWM80_RS04925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWM80_RS04935	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AWM80_RS04945	COG1476	TRANSCRIPTIONal
AWM80_RS04955	COG3382	B3 4 domain protein
AWM80_RS04960	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AWM80_RS04970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AWM80_RS04975	COG0789	Transcriptional regulator
AWM80_RS04980	COG1664	Polymer-forming cytoskeletal
AWM80_RS04985	COG1664	Polymer-forming cytoskeletal
AWM80_RS04990	COG2766	serine protein kinase
AWM80_RS04995	COG2718	Belongs to the UPF0229 family
AWM80_RS05005	COG1846	Transcriptional regulator
AWM80_RS05010	COG1566	PFAM secretion protein HlyD family protein
AWM80_RS05015	COG2814	Major facilitator Superfamily
AWM80_RS05020	COG0655	NAD(P)H dehydrogenase (quinone) activity
AWM80_RS05035	COG1725	Transcriptional regulator
AWM80_RS05040	COG1131	(ABC) transporter
AWM80_RS05045	COG1131	(ABC) transporter
AWM80_RS05050	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AWM80_RS05055	COG1278	Cold shock
AWM80_RS05065	COG1464	Belongs to the NlpA lipoprotein family
AWM80_RS05070	COG3706	GGDEF domain
AWM80_RS05075	COG1823	symporter activity
AWM80_RS05095	COG5577	PFAM Coat F domain
AWM80_RS05100	COG4085	toxin activity
AWM80_RS05100	COG0737	Belongs to the 5'-nucleotidase family
AWM80_RS05100	COG1525	nuclease
AWM80_RS05105	COG3764	Sortase (surface protein transpeptidase)
AWM80_RS05110	COG0564	pseudouridine synthase activity
AWM80_RS05120	COG0517	IMP dehydrogenase activity
AWM80_RS05125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWM80_RS05130	COG3153	acetyltransferase
AWM80_RS05130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWM80_RS05135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AWM80_RS05140	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AWM80_RS05145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWM80_RS05150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AWM80_RS05155	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AWM80_RS05160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWM80_RS05165	COG2203	Gaf domain
AWM80_RS05165	COG4585	Histidine kinase
AWM80_RS05170	COG2197	response regulator
AWM80_RS05175	COG0431	NADPH-dependent FMN reductase
AWM80_RS05190	COG1388	LysM domain
AWM80_RS05190	COG0791	NLP P60 protein
AWM80_RS05195	COG1959	2 iron, 2 sulfur cluster binding
AWM80_RS05200	COG0668	transmembrane transport
AWM80_RS05205	COG2719	SpoVR family
AWM80_RS05210	COG1785	Belongs to the alkaline phosphatase family
AWM80_RS05215	COG0791	NLP P60 protein
AWM80_RS05215	COG1388	LysM domain
AWM80_RS05220	COG0583	DNA-binding transcription factor activity
AWM80_RS05225	COG0372	Belongs to the citrate synthase family
AWM80_RS05230	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS05235	COG0531	amino acid
AWM80_RS05240	COG0733	neurotransmitter:sodium symporter activity
AWM80_RS05245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWM80_RS05250	COG0456	acetyltransferase
AWM80_RS05265	COG1595	DNA-templated transcription, initiation
AWM80_RS05270	COG0667	Aldo Keto reductase
AWM80_RS05275	COG0204	Acyl-transferase
AWM80_RS05280	COG1253	flavin adenine dinucleotide binding
AWM80_RS05285	COG0789	Transcriptional regulator
AWM80_RS05290	COG0436	Aminotransferase
AWM80_RS05295	COG1253	flavin adenine dinucleotide binding
AWM80_RS05300	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AWM80_RS05305	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AWM80_RS05310	COG0584	glycerophosphoryl diester phosphodiesterase
AWM80_RS05320	COG0668	transmembrane transport
AWM80_RS05325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AWM80_RS05330	COG0726	polysaccharide deacetylase
AWM80_RS05335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWM80_RS05340	COG1757	Na H antiporter
AWM80_RS05345	COG0589	response to stress
AWM80_RS05355	COG1132	(ABC) transporter
AWM80_RS05360	COG1132	(ABC) transporter
AWM80_RS05365	COG0702	epimerase
AWM80_RS05380	COG0189	ligase activity
AWM80_RS05385	COG0189	ligase activity
AWM80_RS05390	COG4399	Belongs to the UPF0754 family
AWM80_RS05395	COG3679	Belongs to the UPF0342 family
AWM80_RS05400	COG4335	DNA alkylation repair
AWM80_RS05405	COG0561	phosphatase activity
AWM80_RS05410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWM80_RS05415	COG0475	glutathione-regulated potassium exporter activity
AWM80_RS05420	COG0490	domain, Protein
AWM80_RS05430	COG1024	Enoyl-CoA hydratase
AWM80_RS05440	COG4152	abc transporter atp-binding protein
AWM80_RS05445	COG1668	transmembrane transport
AWM80_RS05450	COG0420	3'-5' exonuclease activity
AWM80_RS05455	COG4717	serine-type aminopeptidase activity
AWM80_RS05460	COG3481	metal-dependent phosphohydrolase, HD sub domain
AWM80_RS05470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWM80_RS05490	COG1846	Transcriptional regulator
AWM80_RS05495	COG4980	gas vesicle protein
AWM80_RS05510	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AWM80_RS05515	COG0537	adenosine 5'-monophosphoramidase activity
AWM80_RS05520	COG1131	(ABC) transporter
AWM80_RS05525	COG4473	ABC transporter
AWM80_RS05535	COG1473	amidohydrolase
AWM80_RS05540	COG3069	C4-dicarboxylate transmembrane transporter activity
AWM80_RS05550	COG2329	Antibiotic biosynthesis monooxygenase
AWM80_RS05555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWM80_RS05560	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AWM80_RS05565	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWM80_RS05570	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AWM80_RS05575	COG1309	transcriptional regulator
AWM80_RS05580	COG1511	domain protein
AWM80_RS05585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWM80_RS05590	COG4377	Putative membrane peptidase family (DUF2324)
AWM80_RS05600	COG1363	Peptidase, m42
AWM80_RS05605	COG4405	Protein conserved in bacteria
AWM80_RS05610	COG1301	dicarboxylic acid transport
AWM80_RS05620	COG1234	tRNA 3'-trailer cleavage
AWM80_RS05625	COG0095	Lipoate-protein ligase
AWM80_RS05630	COG0702	epimerase
AWM80_RS05635	COG0318	PFAM AMP-dependent synthetase and ligase
AWM80_RS05645	COG0501	Belongs to the peptidase M48B family
AWM80_RS05650	COG1404	Belongs to the peptidase S8 family
AWM80_RS05655	COG0456	acetyltransferase
AWM80_RS05660	COG0604	alcohol dehydrogenase
AWM80_RS05665	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AWM80_RS05670	COG0406	alpha-ribazole phosphatase activity
AWM80_RS05675	COG0183	Belongs to the thiolase family
AWM80_RS05680	COG0318	PFAM AMP-dependent synthetase and ligase
AWM80_RS05685	COG1268	BioY protein
AWM80_RS05690	COG0840	transmembrane signaling receptor activity
AWM80_RS05695	COG0723	plastoquinol--plastocyanin reductase activity
AWM80_RS05695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWM80_RS05700	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS05710	COG4903	ComK protein
AWM80_RS05715	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS05725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWM80_RS05740	COG0398	Pfam SNARE associated Golgi protein
AWM80_RS05745	COG0681	Belongs to the peptidase S26 family
AWM80_RS05750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWM80_RS05755	COG1846	Transcriptional regulator
AWM80_RS05760	COG0738	Major facilitator superfamily
AWM80_RS05765	COG0673	inositol 2-dehydrogenase activity
AWM80_RS05770	COG0561	phosphatase activity
AWM80_RS05775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AWM80_RS05780	COG1609	Transcriptional regulator
AWM80_RS05785	COG3180	Ammonia monooxygenase
AWM80_RS05790	COG0477	Major facilitator Superfamily
AWM80_RS05790	COG2814	Major facilitator Superfamily
AWM80_RS05795	COG4533	DNA binding
AWM80_RS05805	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AWM80_RS05810	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AWM80_RS05815	COG1074	ATP-dependent DNA helicase activity
AWM80_RS05820	COG0420	3'-5' exonuclease activity
AWM80_RS05825	COG0419	ATPase involved in DNA repair
AWM80_RS05830	COG1403	HNH endonuclease
AWM80_RS05875	COG5337	Spore coat protein CotH
AWM80_RS05880	COG0179	Fumarylacetoacetate (FAA) hydrolase
AWM80_RS05890	COG1404	Belongs to the peptidase S8 family
AWM80_RS05900	COG0367	asparagine synthase
AWM80_RS05905	COG2318	DinB family
AWM80_RS05910	COG1562	ergosterol biosynthetic process
AWM80_RS05915	COG0534	Mate efflux family protein
AWM80_RS05920	COG2207	Transcriptional regulator
AWM80_RS05920	COG1917	Cupin 2, conserved barrel domain protein
AWM80_RS05925	COG1609	Transcriptional regulator
AWM80_RS05930	COG0673	inositol 2-dehydrogenase activity
AWM80_RS05935	COG2318	DinB family
AWM80_RS05940	COG1279	arginine transmembrane transporter activity
AWM80_RS05945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWM80_RS05950	COG1357	PFAM Pentapeptide repeats (8 copies)
AWM80_RS05955	COG2267	carboxylic ester hydrolase activity
AWM80_RS05960	COG0529	Catalyzes the synthesis of activated sulfate
AWM80_RS05965	COG2046	Belongs to the sulfate adenylyltransferase family
AWM80_RS05970	COG0175	sulfate reduction
AWM80_RS05975	COG2045	Belongs to the ComB family
AWM80_RS05980	COG1809	phosphosulfolactate synthase activity
AWM80_RS05985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWM80_RS05990	COG4948	Mandelate Racemase Muconate Lactonizing
AWM80_RS05995	COG2814	Major facilitator Superfamily
AWM80_RS06000	COG0454	-acetyltransferase
AWM80_RS06005	COG2153	protein acetylation
AWM80_RS06010	COG0646	methionine synthase
AWM80_RS06010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AWM80_RS06015	COG1666	GTP binding
AWM80_RS06020	COG2996	Protein conserved in bacteria
AWM80_RS06040	COG1695	Transcriptional regulator
AWM80_RS06055	COG3227	Zinc metalloprotease (Elastase)
AWM80_RS06060	COG1307	EDD domain protein, DegV family
AWM80_RS06065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWM80_RS06085	COG0561	phosphatase activity
AWM80_RS06090	COG1073	alpha beta
AWM80_RS06095	COG2151	metal-sulfur cluster biosynthetic enzyme
AWM80_RS06105	COG0277	FAD linked oxidase domain protein
AWM80_RS06110	COG2271	Major facilitator Superfamily
AWM80_RS06115	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AWM80_RS06120	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AWM80_RS06130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWM80_RS06135	COG0505	Belongs to the CarA family
AWM80_RS06140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWM80_RS06145	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AWM80_RS06160	COG2267	carboxylic ester hydrolase activity
AWM80_RS06170	COG1744	ABC transporter substrate-binding protein PnrA-like
AWM80_RS06185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWM80_RS06190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWM80_RS06195	COG5504	Zn-dependent protease
AWM80_RS06200	COG0444	Belongs to the ABC transporter superfamily
AWM80_RS06205	COG4608	Belongs to the ABC transporter superfamily
AWM80_RS06215	COG0601	transmembrane transport
AWM80_RS06220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWM80_RS06230	COG0180	Tryptophanyl-tRNA synthetase
AWM80_RS06235	COG4166	transmembrane transport
AWM80_RS06240	COG0601	transmembrane transport
AWM80_RS06245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWM80_RS06250	COG0444	Belongs to the ABC transporter superfamily
AWM80_RS06255	COG4608	Belongs to the ABC transporter superfamily
AWM80_RS06260	COG2814	Major facilitator Superfamily
AWM80_RS06265	COG0456	acetyltransferase
AWM80_RS06270	COG1393	Belongs to the ArsC family
AWM80_RS06275	COG0861	Integral membrane protein TerC family
AWM80_RS06280	COG4862	establishment of competence for transformation
AWM80_RS06285	COG4469	Competence protein
AWM80_RS06290	COG1164	Oligoendopeptidase f
AWM80_RS06305	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AWM80_RS06310	COG2346	COG2346, Truncated hemoglobins
AWM80_RS06315	COG0741	lytic transglycosylase activity
AWM80_RS06320	COG4116	CYTH
AWM80_RS06330	COG2357	RelA SpoT domain protein
AWM80_RS06335	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWM80_RS06340	COG0564	pseudouridine synthase activity
AWM80_RS06345	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AWM80_RS06350	COG0475	glutathione-regulated potassium exporter activity
AWM80_RS06350	COG0569	domain protein
AWM80_RS06355	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AWM80_RS06360	COG0352	thiamine-phosphate diphosphorylase activity
AWM80_RS06365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWM80_RS06370	COG2104	thiamine diphosphate biosynthetic process
AWM80_RS06375	COG2022	thiamine diphosphate biosynthetic process
AWM80_RS06380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWM80_RS06385	COG0351	phosphomethylpyrimidine kinase
AWM80_RS06390	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AWM80_RS06450	COG0210	DNA helicase
AWM80_RS06460	COG2153	protein acetylation
AWM80_RS06465	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AWM80_RS06470	COG2382	esterase
AWM80_RS06475	COG0626	cystathionine gamma-synthase activity
AWM80_RS06480	COG0626	cystathionine gamma-synthase activity
AWM80_RS06485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWM80_RS06490	COG5505	Protein of unknown function (DUF819)
AWM80_RS06525	COG3677	Transposase
AWM80_RS06540	COG5484	DNA packaging
AWM80_RS06545	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AWM80_RS06550	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS06560	COG3711	transcriptional antiterminator
AWM80_RS06560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWM80_RS06565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWM80_RS06565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWM80_RS06565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWM80_RS06570	COG1482	cell wall glycoprotein biosynthetic process
AWM80_RS06580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWM80_RS06590	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AWM80_RS06605	COG0109	protoheme IX farnesyltransferase activity
AWM80_RS06615	COG0726	polysaccharide deacetylase
AWM80_RS06635	COG5504	Zn-dependent protease
AWM80_RS06640	COG2205	protein histidine kinase activity
AWM80_RS06650	COG3383	formate dehydrogenase (NAD+) activity
AWM80_RS06655	COG2427	Protein of unknown function (DUF1641)
AWM80_RS06665	COG1051	belongs to the nudix hydrolase family
AWM80_RS06675	COG2124	cytochrome p450
AWM80_RS06680	COG1819	glycosyl
AWM80_RS06690	COG1587	Uroporphyrinogen-III synthase
AWM80_RS06695	COG0390	transport system, permease component
AWM80_RS06700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWM80_RS06705	COG0697	spore germination
AWM80_RS06710	COG4297	protein containing double-stranded beta helix domain
AWM80_RS06720	COG1252	NADH dehydrogenase
AWM80_RS06725	COG1904	glucuronate isomerase
AWM80_RS06730	COG2211	Major facilitator Superfamily
AWM80_RS06735	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AWM80_RS06740	COG1063	alcohol dehydrogenase
AWM80_RS06745	COG1312	Catalyzes the dehydration of D-mannonate
AWM80_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS06755	COG2271	Major facilitator Superfamily
AWM80_RS06760	COG1609	Transcriptional regulator
AWM80_RS06765	COG0246	Mannitol dehydrogenase
AWM80_RS06770	COG2721	sulfolactate sulfo-lyase activity
AWM80_RS06775	COG0730	response to heat
AWM80_RS06780	COG2318	DinB family
AWM80_RS06785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWM80_RS06790	COG0457	Tetratricopeptide repeat
AWM80_RS06800	COG2350	Protein conserved in bacteria
AWM80_RS06805	COG1388	LysM domain
AWM80_RS06805	COG3409	Peptidoglycan-binding domain 1 protein
AWM80_RS06805	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWM80_RS06815	COG4195	phage-related replication protein
AWM80_RS06820	COG3546	catalase activity
AWM80_RS06825	COG2856	Zn peptidase
AWM80_RS06830	COG1396	sequence-specific DNA binding
AWM80_RS06840	COG1522	sequence-specific DNA binding
AWM80_RS06845	COG1484	DNA-dependent DNA replication
AWM80_RS06870	COG1595	DNA-templated transcription, initiation
AWM80_RS06875	COG5484	DNA packaging
AWM80_RS06875	COG3728	DNA packaging
AWM80_RS06880	COG1783	phage Terminase large subunit
AWM80_RS06885	COG5518	Phage portal protein
AWM80_RS06890	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AWM80_RS06895	COG4653	Phage capsid family
AWM80_RS06945	COG3953	SLT domain
AWM80_RS06945	COG5412	phage tail tape measure protein
AWM80_RS06950	COG1652	LysM domain
AWM80_RS06955	COG4193	domain, Protein
AWM80_RS06965	COG3628	GPW Gp25 family protein
AWM80_RS06970	COG3299	homolog of phage Mu protein gp47
AWM80_RS06975	COG3778	Protein conserved in bacteria
AWM80_RS07015	COG3409	Peptidoglycan-binding domain 1 protein
AWM80_RS07015	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWM80_RS07030	COG0306	phosphate transporter
AWM80_RS07035	COG1392	Phosphate transport regulator
AWM80_RS07040	COG0531	amino acid
AWM80_RS07045	COG0346	lactoylglutathione lyase activity
AWM80_RS07050	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWM80_RS07055	COG0463	Glycosyl transferase, family 2
AWM80_RS07065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWM80_RS07070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWM80_RS07075	COG2362	D-Aminopeptidase
AWM80_RS07080	COG0601	transmembrane transport
AWM80_RS07085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWM80_RS07090	COG0444	Belongs to the ABC transporter superfamily
AWM80_RS07095	COG4166	transmembrane transport
AWM80_RS07100	COG1619	proteins homologs of microcin C7 resistance protein MccF
AWM80_RS07105	COG4948	Mandelate Racemase Muconate Lactonizing
AWM80_RS07110	COG0791	NLP P60 protein
AWM80_RS07115	COG4608	Belongs to the ABC transporter superfamily
AWM80_RS07120	COG2706	6-phosphogluconolactonase activity
AWM80_RS07125	COG1834	amidinotransferase
AWM80_RS07130	COG1607	acyl-coa hydrolase
AWM80_RS07135	COG1017	nitric oxide dioxygenase activity
AWM80_RS07135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWM80_RS07145	COG2323	membrane
AWM80_RS07150	COG2318	DinB family
AWM80_RS07155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWM80_RS07160	COG2076	Multidrug Resistance protein
AWM80_RS07165	COG2076	Multidrug Resistance protein
AWM80_RS07170	COG0788	formyltetrahydrofolate deformylase activity
AWM80_RS07175	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AWM80_RS07180	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWM80_RS07185	COG1764	response to oxidative stress
AWM80_RS07190	COG1846	Transcriptional regulator
AWM80_RS07195	COG1764	response to oxidative stress
AWM80_RS07205	COG0590	tRNA wobble adenosine to inosine editing
AWM80_RS07210	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWM80_RS07215	COG1404	Belongs to the peptidase S8 family
AWM80_RS07220	COG1366	Belongs to the anti-sigma-factor antagonist family
AWM80_RS07225	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AWM80_RS07230	COG1122	ATPase activity
AWM80_RS07235	COG4721	ABC-type cobalt transport system, permease component
AWM80_RS07245	COG0745	RESPONSE REGULATOR receiver
AWM80_RS07250	COG5002	protein histidine kinase activity
AWM80_RS07250	COG3850	Histidine kinase
AWM80_RS07255	COG3212	peptidase
AWM80_RS07260	COG3212	peptidase
AWM80_RS07280	COG2239	Acts as a magnesium transporter
AWM80_RS07285	COG0789	Transcriptional regulator
AWM80_RS07300	COG1846	Transcriptional regulator
AWM80_RS07305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWM80_RS07310	COG0726	polysaccharide deacetylase
AWM80_RS07315	COG1408	metallophosphoesterase
AWM80_RS07325	COG0463	Glycosyl transferase, family 2
AWM80_RS07330	COG1793	dna ligase
AWM80_RS07330	COG3285	dna ligase
AWM80_RS07335	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AWM80_RS07340	COG3300	MHYT domain
AWM80_RS07340	COG5001	Diguanylate cyclase
AWM80_RS07345	COG0586	Pfam SNARE associated Golgi protein
AWM80_RS07350	COG0861	Integral membrane protein TerC family
AWM80_RS07355	COG1191	sigma factor activity
AWM80_RS07375	COG0501	Belongs to the peptidase M48B family
AWM80_RS07380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWM80_RS07395	COG3594	Acyltransferase
AWM80_RS07400	COG5002	protein histidine kinase activity
AWM80_RS07405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AWM80_RS07415	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AWM80_RS07420	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AWM80_RS07425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWM80_RS07430	COG0436	Aminotransferase
AWM80_RS07435	COG1850	ribulose-bisphosphate carboxylase activity
AWM80_RS07440	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AWM80_RS07445	COG0235	Class ii aldolase
AWM80_RS07450	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AWM80_RS07455	COG3339	Conserved Protein
AWM80_RS07470	COG3852	Histidine kinase
AWM80_RS07475	COG1846	Transcriptional regulator
AWM80_RS07480	COG1360	Flagellar Motor Protein
AWM80_RS07485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AWM80_RS07490	COG0542	response to heat
AWM80_RS07495	COG3949	Membrane
AWM80_RS07500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AWM80_RS07505	COG0720	synthase
AWM80_RS07510	COG0602	queuosine metabolic process
AWM80_RS07515	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AWM80_RS07520	COG1733	regulation of RNA biosynthetic process
AWM80_RS07525	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS07530	COG1388	LysM domain
AWM80_RS07530	COG4641	Protein conserved in bacteria
AWM80_RS07535	COG1388	LysM domain
AWM80_RS07540	COG3858	chitin binding
AWM80_RS07545	COG3858	chitin binding
AWM80_RS07555	COG4873	Protein conserved in bacteria
AWM80_RS07570	COG3773	Cell wall hydrolase
AWM80_RS07575	COG2244	polysaccharide biosynthetic process
AWM80_RS07580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWM80_RS07585	COG2217	Heavy metal translocating P-type atpase
AWM80_RS07595	COG0006	proline dipeptidase activity
AWM80_RS07605	COG1609	Transcriptional regulator
AWM80_RS07610	COG3711	transcriptional antiterminator
AWM80_RS07615	COG2190	(PTS) system
AWM80_RS07615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWM80_RS07615	COG1263	PTS System
AWM80_RS07620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWM80_RS07625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AWM80_RS07635	COG1533	DNA photolyase activity
AWM80_RS07640	COG0456	acetyltransferase
AWM80_RS07645	COG0840	transmembrane signaling receptor activity
AWM80_RS07650	COG2084	Dehydrogenase
AWM80_RS07655	COG2340	Cysteine-rich secretory protein family
AWM80_RS07660	COG0768	penicillin binding
AWM80_RS07665	COG4191	Histidine kinase
AWM80_RS07670	COG0436	Aminotransferase
AWM80_RS07680	COG0835	chemotaxis
AWM80_RS07680	COG0784	Response regulator, receiver
AWM80_RS07690	COG2814	Major facilitator Superfamily
AWM80_RS07695	COG1376	ErfK ybiS ycfS ynhG family protein
AWM80_RS07700	COG1408	metallophosphoesterase
AWM80_RS07705	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS07710	COG3409	Peptidoglycan-binding domain 1 protein
AWM80_RS07715	COG3409	Peptidoglycan-binding domain 1 protein
AWM80_RS07725	COG2200	EAL domain
AWM80_RS07735	COG4703	Protein of unknown function (DUF1797)
AWM80_RS07740	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AWM80_RS07750	COG0517	IMP dehydrogenase activity
AWM80_RS07755	COG0583	DNA-binding transcription factor activity
AWM80_RS07760	COG0716	FMN binding
AWM80_RS07770	COG0716	FMN binding
AWM80_RS07775	COG2171	N-acyltransferase activity
AWM80_RS07780	COG1473	amidohydrolase
AWM80_RS07790	COG0668	transmembrane transport
AWM80_RS07795	COG0450	alkyl hydroperoxide reductase
AWM80_RS07800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWM80_RS07815	COG0746	molybdenum cofactor guanylyltransferase activity
AWM80_RS07820	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWM80_RS07825	COG0303	'Molybdopterin
AWM80_RS07830	COG1763	Mo-molybdopterin cofactor biosynthetic process
AWM80_RS07835	COG0314	molybdopterin synthase activity
AWM80_RS07840	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AWM80_RS07845	COG1132	(ABC) transporter
AWM80_RS07850	COG1132	(ABC) transporter
AWM80_RS07860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWM80_RS07865	COG1136	(ABC) transporter
AWM80_RS07870	COG0577	efflux transmembrane transporter activity
AWM80_RS07875	COG1349	DNA-binding transcription factor activity
AWM80_RS07880	COG1105	Belongs to the carbohydrate kinase PfkB family
AWM80_RS07885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWM80_RS07885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWM80_RS07885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWM80_RS07890	COG0681	Belongs to the peptidase S26 family
AWM80_RS07900	COG0488	(ABC) transporter
AWM80_RS07905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AWM80_RS07910	COG2309	aminopeptidase activity
AWM80_RS07920	COG1077	Cell shape determining protein MreB Mrl
AWM80_RS07925	COG2002	toxin-antitoxin pair type II binding
AWM80_RS07930	COG3852	Histidine kinase
AWM80_RS07935	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AWM80_RS07935	COG2105	PFAM AIG2 family protein
AWM80_RS07940	COG0569	domain protein
AWM80_RS07945	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AWM80_RS07950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AWM80_RS07955	COG5503	Protein of unknown function (DUF1447)
AWM80_RS07960	COG0561	phosphatase activity
AWM80_RS07965	COG0242	peptide deformylase activity
AWM80_RS07975	COG0497	DNA recombination
AWM80_RS07980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWM80_RS07985	COG0022	dehydrogenase e1 component
AWM80_RS07990	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWM80_RS07995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWM80_RS08000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWM80_RS08005	COG1982	Orn Lys Arg decarboxylase major
AWM80_RS08010	COG4476	Belongs to the UPF0223 family
AWM80_RS08015	COG4493	Belongs to the UPF0637 family
AWM80_RS08025	COG0483	inositol monophosphate 1-phosphatase activity
AWM80_RS08035	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AWM80_RS08055	COG1595	DNA-templated transcription, initiation
AWM80_RS08075	COG1217	gtp-binding protein TYPA
AWM80_RS08085	COG4896	Protein conserved in bacteria
AWM80_RS08095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AWM80_RS08100	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AWM80_RS08105	COG2066	Belongs to the glutaminase family
AWM80_RS08110	COG4838	Belongs to the UPF0358 family
AWM80_RS08115	COG0772	Belongs to the SEDS family
AWM80_RS08120	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AWM80_RS08125	COG1612	heme a metabolic process
AWM80_RS08130	COG0109	protoheme IX farnesyltransferase activity
AWM80_RS08135	COG2010	Cytochrome c
AWM80_RS08135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWM80_RS08140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWM80_RS08145	COG1845	cytochrome c oxidase, subunit III
AWM80_RS08150	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AWM80_RS08155	COG3336	cytochrome c oxidase
AWM80_RS08165	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AWM80_RS08170	COG2340	Cysteine-rich secretory protein family
AWM80_RS08185	COG3679	Belongs to the UPF0342 family
AWM80_RS08190	COG4471	UPF0298 protein
AWM80_RS08195	COG0742	ribosomal rna small subunit methyltransferase
AWM80_RS08200	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AWM80_RS08205	COG3314	Sporulation integral membrane protein YlbJ
AWM80_RS08210	COG1752	Esterase of the alpha-beta hydrolase superfamily
AWM80_RS08215	COG3480	Lon protease (S16) C-terminal proteolytic domain
AWM80_RS08220	COG1323	Belongs to the UPF0348 family
AWM80_RS08230	COG1399	metal-binding, possibly nucleic acid-binding protein
AWM80_RS08245	COG0454	-acetyltransferase
AWM80_RS08250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AWM80_RS08260	COG2001	Belongs to the MraZ family
AWM80_RS08265	COG0275	rRNA processing
AWM80_RS08270	COG4839	cell division protein FtsL
AWM80_RS08275	COG0768	penicillin binding
AWM80_RS08285	COG0768	penicillin binding
AWM80_RS08295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AWM80_RS08305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWM80_RS08310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AWM80_RS08315	COG0772	Belongs to the SEDS family
AWM80_RS08320	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWM80_RS08325	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AWM80_RS08330	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AWM80_RS08335	COG3879	Bacterial protein of unknown function (DUF881)
AWM80_RS08340	COG3879	Bacterial protein of unknown function (DUF881)
AWM80_RS08345	COG3856	small basic protein
AWM80_RS08350	COG0849	cell division
AWM80_RS08355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AWM80_RS08360	COG1404	Belongs to the peptidase S8 family
AWM80_RS08360	COG4412	M6 family metalloprotease domain protein
AWM80_RS08370	COG1191	sigma factor activity
AWM80_RS08375	COG1191	sigma factor activity
AWM80_RS08380	COG1119	ATPase activity
AWM80_RS08385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWM80_RS08390	COG1873	PFAM PRC-barrel domain
AWM80_RS08395	COG1496	oxidoreductase activity
AWM80_RS08400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AWM80_RS08405	COG1799	cell septum assembly
AWM80_RS08410	COG0762	integral membrane protein
AWM80_RS08415	COG2302	S4 RNA-binding domain
AWM80_RS08420	COG3599	regulation of cell shape
AWM80_RS08425	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AWM80_RS08430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AWM80_RS08435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AWM80_RS08440	COG0564	pseudouridine synthase activity
AWM80_RS08445	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AWM80_RS08450	COG2233	PERMEase
AWM80_RS08455	COG0540	Belongs to the ATCase OTCase family
AWM80_RS08460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWM80_RS08465	COG0505	Belongs to the CarA family
AWM80_RS08470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWM80_RS08475	COG0543	2 iron, 2 sulfur cluster binding
AWM80_RS08480	COG0167	dihydroorotate dehydrogenase activity
AWM80_RS08485	COG0284	orotidine-5'-phosphate decarboxylase activity
AWM80_RS08490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWM80_RS08495	COG0175	sulfate reduction
AWM80_RS08500	COG0306	phosphate transporter
AWM80_RS08505	COG2046	Belongs to the sulfate adenylyltransferase family
AWM80_RS08510	COG0529	Catalyzes the synthesis of activated sulfate
AWM80_RS08515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWM80_RS08520	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AWM80_RS08525	COG1648	precorrin-2 dehydrogenase activity
AWM80_RS08530	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AWM80_RS08535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWM80_RS08540	COG1561	YicC-like family, N-terminal region
AWM80_RS08550	COG0194	GDP metabolic process
AWM80_RS08555	COG1758	RNA polymerase activity
AWM80_RS08560	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWM80_RS08565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWM80_RS08570	COG0242	peptide deformylase activity
AWM80_RS08575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AWM80_RS08580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWM80_RS08580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWM80_RS08585	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AWM80_RS08590	COG0631	protein serine/threonine phosphatase activity
AWM80_RS08595	COG0515	serine threonine protein kinase
AWM80_RS08595	COG2815	serine threonine protein kinase
AWM80_RS08600	COG1162	GTPase activity
AWM80_RS08605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AWM80_RS08610	COG1564	THIamine pyrophosphokinase
AWM80_RS08620	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AWM80_RS08625	COG1302	Protein conserved in bacteria
AWM80_RS08630	COG1461	Dihydroxyacetone kinase
AWM80_RS08635	COG1760	l-serine dehydratase
AWM80_RS08640	COG1760	l-serine dehydratase
AWM80_RS08645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWM80_RS08650	COG1349	DNA-binding transcription factor activity
AWM80_RS08650	COG2050	protein possibly involved in aromatic compounds catabolism
AWM80_RS08655	COG0416	fatty acid biosynthetic process
AWM80_RS08660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AWM80_RS08665	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS08675	COG0571	ribonuclease III activity
AWM80_RS08680	COG1196	nuclear chromosome segregation
AWM80_RS08685	COG0552	protein localization to endoplasmic reticulum
AWM80_RS08695	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AWM80_RS08700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AWM80_RS08705	COG0228	four-way junction DNA binding
AWM80_RS08710	COG1837	Belongs to the UPF0109 family
AWM80_RS08720	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AWM80_RS08725	COG0336	Belongs to the RNA methyltransferase TrmD family
AWM80_RS08730	COG0335	large ribosomal subunit rRNA binding
AWM80_RS08735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AWM80_RS08740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWM80_RS08750	COG2257	FlhB HrpN YscU SpaS Family
AWM80_RS08755	COG0045	succinate-CoA ligase (ADP-forming) activity
AWM80_RS08760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AWM80_RS08765	COG0758	DNA mediated transformation
AWM80_RS08770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWM80_RS08775	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AWM80_RS08780	COG4974	Belongs to the 'phage' integrase family
AWM80_RS08785	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AWM80_RS08790	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AWM80_RS08795	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AWM80_RS08800	COG1815	bacterial-type flagellum-dependent cell motility
AWM80_RS08805	COG1558	bacterial-type flagellum-dependent cell motility
AWM80_RS08810	COG1677	Flagellar hook-basal body complex protein FliE
AWM80_RS08815	COG1766	The M ring may be actively involved in energy transduction
AWM80_RS08820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AWM80_RS08825	COG1317	bacterial-type flagellum organization
AWM80_RS08830	COG1157	protein secretion by the type III secretion system
AWM80_RS08835	COG2882	bacterial-type flagellum organization
AWM80_RS08840	COG3334	PFAM MgtE intracellular
AWM80_RS08845	COG3144	bacterial-type flagellum assembly
AWM80_RS08850	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AWM80_RS08855	COG4786	Flagellar basal body rod
AWM80_RS08860	COG1582	Flagellar protein (FlbD)
AWM80_RS08865	COG1580	Controls the rotational direction of flagella during chemotaxis
AWM80_RS08870	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AWM80_RS08875	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AWM80_RS08875	COG1776	CheC inhibitor of MCP methylation
AWM80_RS08880	COG2201	protein-glutamate methylesterase activity
AWM80_RS08885	COG3190	flagellar
AWM80_RS08890	COG1338	Plays a role in the flagellum-specific transport system
AWM80_RS08895	COG1987	bacterial-type flagellum assembly
AWM80_RS08900	COG1684	flagellar biosynthetic protein fliR
AWM80_RS08905	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AWM80_RS08910	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AWM80_RS08915	COG1419	protein localization to endoplasmic reticulum
AWM80_RS08920	COG0455	bacterial-type flagellum organization
AWM80_RS08925	COG2201	protein-glutamate methylesterase activity
AWM80_RS08930	COG2198	Histidine kinase
AWM80_RS08930	COG0643	Histidine kinase
AWM80_RS08935	COG0835	chemotaxis
AWM80_RS08940	COG1776	CheC inhibitor of MCP methylation
AWM80_RS08945	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AWM80_RS08950	COG1191	sigma factor activity
AWM80_RS08960	COG0052	Belongs to the universal ribosomal protein uS2 family
AWM80_RS08965	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AWM80_RS08970	COG0528	UMP kinase activity
AWM80_RS08975	COG0233	cytoplasmic translational termination
AWM80_RS08980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AWM80_RS08985	COG4589	Belongs to the CDS family
AWM80_RS08990	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AWM80_RS08995	COG0750	zinc metalloprotease
AWM80_RS09000	COG0442	prolyl-tRNA aminoacylation
AWM80_RS09005	COG2176	DNA-directed DNA polymerase activity
AWM80_RS09010	COG0779	Required for maturation of 30S ribosomal subunits
AWM80_RS09015	COG0195	Participates in both transcription termination and antitermination
AWM80_RS09020	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AWM80_RS09025	COG1358	cellular component organization or biogenesis
AWM80_RS09030	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AWM80_RS09035	COG1550	Protein conserved in bacteria
AWM80_RS09040	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AWM80_RS09045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AWM80_RS09050	COG0196	riboflavin kinase activity
AWM80_RS09055	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AWM80_RS09060	COG1185	polyribonucleotide nucleotidyltransferase activity
AWM80_RS09065	COG0726	polysaccharide deacetylase
AWM80_RS09070	COG0612	Peptidase, M16
AWM80_RS09075	COG1873	PFAM PRC-barrel domain
AWM80_RS09085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWM80_RS09090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWM80_RS09095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AWM80_RS09100	COG0527	aspartate kinase activity
AWM80_RS09105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWM80_RS09110	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AWM80_RS09115	COG0740	serine-type endopeptidase activity
AWM80_RS09125	COG4980	gas vesicle protein
AWM80_RS09125	COG1674	ftsk spoiiie
AWM80_RS09130	COG2188	Transcriptional regulator
AWM80_RS09135	COG2814	Major facilitator Superfamily
AWM80_RS09140	COG0612	Peptidase, M16
AWM80_RS09145	COG0612	Peptidase, M16
AWM80_RS09150	COG0300	oxidoreductase activity
AWM80_RS09165	COG1426	Protein conserved in bacteria
AWM80_RS09170	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AWM80_RS09175	COG1058	Belongs to the CinA family
AWM80_RS09175	COG1546	Belongs to the CinA family
AWM80_RS09180	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AWM80_RS09185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AWM80_RS09190	COG1418	mRNA catabolic process
AWM80_RS09195	COG1692	metallophosphoesterase
AWM80_RS09200	COG2359	stage V sporulation protein S
AWM80_RS09205	COG1063	alcohol dehydrogenase
AWM80_RS09210	COG0156	8-amino-7-oxononanoate synthase activity
AWM80_RS09215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWM80_RS09220	COG4550	Control of competence regulator ComK, YlbF/YmcA
AWM80_RS09230	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWM80_RS09235	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AWM80_RS09255	COG3226	Transcriptional regulator
AWM80_RS09260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWM80_RS09270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AWM80_RS09275	COG3321	synthase
AWM80_RS09280	COG2070	2-Nitropropane dioxygenase
AWM80_RS09280	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AWM80_RS09285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWM80_RS09290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWM80_RS09295	COG3425	synthase
AWM80_RS09300	COG1024	Enoyl-CoA hydratase
AWM80_RS09305	COG1024	Enoyl-CoA hydratase
AWM80_RS09310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWM80_RS09310	COG3321	synthase
AWM80_RS09310	COG0318	PFAM AMP-dependent synthetase and ligase
AWM80_RS09310	COG0300	oxidoreductase activity
AWM80_RS09310	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS09315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWM80_RS09315	COG0300	oxidoreductase activity
AWM80_RS09315	COG4221	oxidoreductase activity
AWM80_RS09315	COG3321	synthase
AWM80_RS09320	COG3321	synthase
AWM80_RS09320	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS09320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWM80_RS09320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWM80_RS09320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWM80_RS09330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWM80_RS09330	COG3321	synthase
AWM80_RS09330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWM80_RS09330	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AWM80_RS09335	COG2124	cytochrome p450
AWM80_RS09345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWM80_RS09350	COG1404	Belongs to the peptidase S8 family
AWM80_RS09360	COG4195	phage-related replication protein
AWM80_RS09365	COG1764	response to oxidative stress
AWM80_RS09370	COG2076	Multidrug Resistance protein
AWM80_RS09375	COG2076	Multidrug Resistance protein
AWM80_RS09390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AWM80_RS09395	COG1923	regulation of RNA biosynthetic process
AWM80_RS09410	COG1780	Probably involved in ribonucleotide reductase function
AWM80_RS09415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWM80_RS09420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWM80_RS09425	COG4112	unkown
AWM80_RS09430	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWM80_RS09435	COG0464	growth
AWM80_RS09445	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AWM80_RS09450	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AWM80_RS09455	COG0789	Transcriptional regulator
AWM80_RS09460	COG0174	glutamine synthetase
AWM80_RS09480	COG4282	regulation of fungal-type cell wall biogenesis
AWM80_RS09490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWM80_RS09515	COG0135	phosphoribosylanthranilate isomerase activity
AWM80_RS09520	COG2211	Major facilitator Superfamily
AWM80_RS09525	COG3507	Belongs to the glycosyl hydrolase 43 family
AWM80_RS09530	COG1940	carbohydrate kinase activity
AWM80_RS09535	COG2115	Belongs to the xylose isomerase family
AWM80_RS09540	COG1070	Carbohydrate kinase
AWM80_RS09545	COG1525	nuclease
AWM80_RS09550	COG2814	Major facilitator Superfamily
AWM80_RS09555	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AWM80_RS09565	COG0756	dUTP diphosphatase activity
AWM80_RS09575	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AWM80_RS09600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWM80_RS09615	COG3832	glyoxalase III activity
AWM80_RS09630	COG0697	spore germination
AWM80_RS09635	COG0531	amino acid
AWM80_RS09665	COG4195	phage-related replication protein
AWM80_RS09675	COG0346	lactoylglutathione lyase activity
AWM80_RS09685	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AWM80_RS09690	COG1388	LysM domain
AWM80_RS09695	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AWM80_RS09700	COG4224	UPF0291 protein
AWM80_RS09705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AWM80_RS09715	COG3763	UPF0154 protein
AWM80_RS09725	COG0785	Cytochrome C biogenesis protein
AWM80_RS09730	COG2201	protein-glutamate methylesterase activity
AWM80_RS09735	COG4846	Membrane protein involved in cytochrome C biogenesis
AWM80_RS09745	COG0071	Belongs to the small heat shock protein (HSP20) family
AWM80_RS09760	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AWM80_RS09765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWM80_RS09785	COG0824	Thioesterase
AWM80_RS09795	COG4841	protein insertion into membrane
AWM80_RS09800	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AWM80_RS09805	COG1832	CoA-binding protein
AWM80_RS09810	COG0187	DNA topoisomerase II activity
AWM80_RS09815	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWM80_RS09830	COG1115	amino acid carrier protein
AWM80_RS09835	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AWM80_RS09845	COG5520	Belongs to the glycosyl hydrolase 30 family
AWM80_RS09850	COG3507	Belongs to the glycosyl hydrolase 43 family
AWM80_RS09855	COG2246	polysaccharide biosynthetic process
AWM80_RS09860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AWM80_RS09865	COG0586	Pfam SNARE associated Golgi protein
AWM80_RS09870	COG2404	hydrolase activity, acting on ester bonds
AWM80_RS09875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AWM80_RS09880	COG1024	Enoyl-CoA hydratase
AWM80_RS09885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWM80_RS09890	COG0511	ligase activity, forming carbon-carbon bonds
AWM80_RS09895	COG0439	Biotin carboxylase
AWM80_RS09900	COG0318	PFAM AMP-dependent synthetase and ligase
AWM80_RS09905	COG1960	acyl-CoA dehydrogenase activity
AWM80_RS09920	COG1649	PFAM Uncharacterised BCR, COG1649
AWM80_RS09930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWM80_RS09930	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AWM80_RS09935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWM80_RS09940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWM80_RS09945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWM80_RS09950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWM80_RS09955	COG2027	D-alanyl-D-alanine carboxypeptidase
AWM80_RS09960	COG2017	converts alpha-aldose to the beta-anomer
AWM80_RS09965	COG0534	Mate efflux family protein
AWM80_RS09980	COG0582	viral genome integration into host DNA
AWM80_RS09985	COG0166	Belongs to the GPI family
AWM80_RS09990	COG0405	Gamma-glutamyltransferase
AWM80_RS09995	COG0583	DNA-binding transcription factor activity
AWM80_RS10000	COG0604	alcohol dehydrogenase
AWM80_RS10005	COG0493	'glutamate synthase
AWM80_RS10010	COG0070	glutamate synthase
AWM80_RS10010	COG0067	glutamate synthase
AWM80_RS10010	COG0069	glutamate synthase activity
AWM80_RS10015	COG0583	DNA-binding transcription factor activity
AWM80_RS10020	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AWM80_RS10025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWM80_RS10035	COG0300	oxidoreductase activity
AWM80_RS10040	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AWM80_RS10050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWM80_RS10055	COG2814	Major facilitator Superfamily
AWM80_RS10060	COG1070	Carbohydrate kinase
AWM80_RS10065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWM80_RS10070	COG0243	molybdopterin cofactor binding
AWM80_RS10095	COG5278	phosphoserine phosphatase activity
AWM80_RS10095	COG0840	transmembrane signaling receptor activity
AWM80_RS10100	COG2368	4-hydroxyphenylacetate
AWM80_RS10105	COG4305	rare lipoprotein A
AWM80_RS10110	COG3619	membrane
AWM80_RS10115	COG3866	Pectate lyase
AWM80_RS10120	COG2135	peptidase activity
AWM80_RS10130	COG2140	Oxalate decarboxylase
AWM80_RS10140	COG0456	acetyltransferase
AWM80_RS10160	COG0697	spore germination
AWM80_RS10170	COG0693	protein deglycase activity
AWM80_RS10175	COG2367	Beta-lactamase
AWM80_RS10195	COG0574	Belongs to the PEP-utilizing enzyme family
AWM80_RS10195	COG3848	Pyruvate phosphate dikinase
AWM80_RS10200	COG0726	polysaccharide deacetylase
AWM80_RS10210	COG2314	TM2 domain
AWM80_RS10215	COG1396	sequence-specific DNA binding
AWM80_RS10230	COG2135	peptidase activity
AWM80_RS10235	COG1793	dna ligase
AWM80_RS10265	COG0457	Tetratricopeptide repeat
AWM80_RS10290	COG5290	Psort location Cytoplasmic, score
AWM80_RS10310	COG5444	nuclease activity
AWM80_RS10315	COG4282	regulation of fungal-type cell wall biogenesis
AWM80_RS10320	COG1231	oxidoreductase activity
AWM80_RS10325	COG5434	Belongs to the glycosyl hydrolase 28 family
AWM80_RS10330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWM80_RS10335	COG0662	Cupin 2, conserved barrel domain protein
AWM80_RS10335	COG2207	Transcriptional regulator
AWM80_RS10340	COG0456	acetyltransferase
AWM80_RS10345	COG1309	transcriptional regulator
AWM80_RS10350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWM80_RS10355	COG3708	Transcriptional regulator
AWM80_RS10360	COG2378	regulation of single-species biofilm formation
AWM80_RS10370	COG0640	Transcriptional regulator
AWM80_RS10375	COG0741	lytic transglycosylase activity
AWM80_RS10380	COG2322	membrane
AWM80_RS10395	COG1619	proteins homologs of microcin C7 resistance protein MccF
AWM80_RS10400	COG3239	Fatty acid desaturase
AWM80_RS10405	COG4585	Histidine kinase
AWM80_RS10410	COG2197	response regulator
AWM80_RS10415	COG1388	LysM domain
AWM80_RS10415	COG3584	3D domain protein
AWM80_RS10420	COG0514	ATP-dependent DNA helicase (RecQ)
AWM80_RS10435	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AWM80_RS10440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AWM80_RS10455	COG0071	Belongs to the small heat shock protein (HSP20) family
AWM80_RS10480	COG1012	belongs to the aldehyde dehydrogenase family
AWM80_RS10485	COG1657	PFAM Prenyltransferase squalene oxidase
AWM80_RS10490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AWM80_RS10495	COG0733	neurotransmitter:sodium symporter activity
AWM80_RS10500	COG0385	Bile acid
AWM80_RS10505	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWM80_RS10510	COG0567	Dehydrogenase, E1 component
AWM80_RS10515	COG4548	von Willebrand factor, type A
AWM80_RS10520	COG0714	Associated with various cellular activities
AWM80_RS10525	COG2032	superoxide dismutase activity
AWM80_RS10530	COG1388	LysM domain
AWM80_RS10530	COG0791	NLP P60 protein
AWM80_RS10535	COG1819	glycosyl
AWM80_RS10540	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AWM80_RS10545	COG0534	Mate efflux family protein
AWM80_RS10550	COG1366	Belongs to the anti-sigma-factor antagonist family
AWM80_RS10555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AWM80_RS10560	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AWM80_RS10570	COG2962	Rard protein
AWM80_RS10585	COG2610	gluconate transmembrane transporter activity
AWM80_RS10590	COG1942	4-Oxalocrotonate Tautomerase
AWM80_RS10595	COG1733	regulation of RNA biosynthetic process
AWM80_RS10600	COG0778	Nitroreductase
AWM80_RS10605	COG0400	carboxylic ester hydrolase activity
AWM80_RS10610	COG0346	lactoylglutathione lyase activity
AWM80_RS10620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWM80_RS10625	COG3409	Peptidoglycan-binding domain 1 protein
AWM80_RS10625	COG0793	Belongs to the peptidase S41A family
AWM80_RS10630	COG2226	methyltransferase
AWM80_RS10640	COG1876	peptidase activity
AWM80_RS10645	COG0813	purine-nucleoside phosphorylase activity
AWM80_RS10660	COG0671	phosphoesterase, PA-phosphatase related
AWM80_RS10685	COG4479	Belongs to the UPF0346 family
AWM80_RS10695	COG1509	lysine 2,3-aminomutase activity
AWM80_RS10700	COG0456	acetyltransferase
AWM80_RS10705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWM80_RS10710	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AWM80_RS10715	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AWM80_RS10720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AWM80_RS10735	COG0456	acetyltransferase
AWM80_RS10740	COG0463	Glycosyl transferase, family 2
AWM80_RS10755	COG4641	Protein conserved in bacteria
AWM80_RS10760	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
AWM80_RS10765	COG1086	Polysaccharide biosynthesis protein
AWM80_RS10770	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWM80_RS10775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWM80_RS10780	COG1846	Transcriptional regulator
AWM80_RS10785	COG0534	Mate efflux family protein
AWM80_RS10795	COG4698	Protein conserved in bacteria
AWM80_RS10800	COG2755	lipolytic protein G-D-S-L family
AWM80_RS10805	COG1999	signal sequence binding
AWM80_RS10820	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AWM80_RS10825	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AWM80_RS10830	COG1272	protein, Hemolysin III
AWM80_RS10835	COG0204	Acyl-transferase
AWM80_RS10840	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AWM80_RS10845	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AWM80_RS10850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AWM80_RS10860	COG2136	Putative SAM-dependent methyltransferase
AWM80_RS10860	COG2521	methyltransferase
AWM80_RS10870	COG0129	dihydroxy-acid dehydratase activity
AWM80_RS10875	COG1413	lyase activity
AWM80_RS10880	COG1418	mRNA catabolic process
AWM80_RS10885	COG0386	Belongs to the glutathione peroxidase family
AWM80_RS10895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWM80_RS10900	COG1278	Cold shock
AWM80_RS10920	COG0328	RNA-DNA hybrid ribonuclease activity
AWM80_RS10925	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AWM80_RS10930	COG0328	RNA-DNA hybrid ribonuclease activity
AWM80_RS10940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWM80_RS10960	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AWM80_RS10965	COG1755	Isoprenylcysteine carboxyl methyltransferase
AWM80_RS10970	COG3424	synthase
AWM80_RS10975	COG2233	PERMEase
AWM80_RS10980	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWM80_RS10985	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AWM80_RS10995	COG0800	Aldolase
AWM80_RS11000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWM80_RS11005	COG1609	Transcriptional regulator
AWM80_RS11010	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AWM80_RS11015	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS11020	COG1199	ATP-dependent helicase activity
AWM80_RS11030	COG0116	Belongs to the methyltransferase superfamily
AWM80_RS11045	COG4474	Belongs to the UPF0398 family
AWM80_RS11055	COG3359	exonuclease
AWM80_RS11060	COG1205	dead DEAH box helicase
AWM80_RS11060	COG1111	helicase
AWM80_RS11065	COG2190	(PTS) system
AWM80_RS11070	COG0071	Belongs to the small heat shock protein (HSP20) family
AWM80_RS11105	COG3331	DNA recombination
AWM80_RS11110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWM80_RS11110	COG4499	WXG100 protein secretion system (Wss), protein YukC
AWM80_RS11120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AWM80_RS11125	COG3935	DnaD domain protein
AWM80_RS11130	COG0017	Asparaginyl-tRNA synthetase
AWM80_RS11135	COG0436	Aminotransferase
AWM80_RS11140	COG5353	protein conserved in bacteria
AWM80_RS11150	COG1199	ATP-dependent helicase activity
AWM80_RS11150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AWM80_RS11155	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AWM80_RS11160	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AWM80_RS11165	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AWM80_RS11175	COG0617	tRNA 3'-terminal CCA addition
AWM80_RS11180	COG0438	transferase activity, transferring glycosyl groups
AWM80_RS11185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AWM80_RS11190	COG1803	Methylglyoxal synthase
AWM80_RS11195	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AWM80_RS11200	COG1694	Mazg nucleotide pyrophosphohydrolase
AWM80_RS11205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWM80_RS11215	COG4347	Protein of unknown function (DUF1405)
AWM80_RS11220	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWM80_RS11220	COG2010	Cytochrome c
AWM80_RS11225	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWM80_RS11230	COG0723	plastoquinol--plastocyanin reductase activity
AWM80_RS11240	COG5582	Belongs to the UPF0302 family
AWM80_RS11245	COG0457	Tetratricopeptide repeat
AWM80_RS11250	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AWM80_RS11255	COG0287	Prephenate dehydrogenase
AWM80_RS11260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWM80_RS11265	COG0159	tryptophan synthase activity
AWM80_RS11270	COG0133	tryptophan synthase activity
AWM80_RS11275	COG0135	phosphoribosylanthranilate isomerase activity
AWM80_RS11285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWM80_RS11290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWM80_RS11295	COG4401	Chorismate mutase type I
AWM80_RS11300	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AWM80_RS11305	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AWM80_RS11310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AWM80_RS11320	COG0105	UTP biosynthetic process
AWM80_RS11325	COG0142	geranyltranstransferase activity
AWM80_RS11330	COG2226	methyltransferase
AWM80_RS11335	COG0142	geranyltranstransferase activity
AWM80_RS11345	COG0302	gtp cyclohydrolase
AWM80_RS11350	COG0776	regulation of translation
AWM80_RS11355	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AWM80_RS11370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AWM80_RS11375	COG1160	GTP binding
AWM80_RS11400	COG1304	FMN binding
AWM80_RS11405	COG0539	negative regulation of cytoplasmic translation
AWM80_RS11410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AWM80_RS11420	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AWM80_RS11425	COG2959	enzyme of heme biosynthesis
AWM80_RS11430	COG3773	Cell wall hydrolase
AWM80_RS11430	COG3409	Peptidoglycan-binding domain 1 protein
AWM80_RS11435	COG2339	peptidase activity
AWM80_RS11440	COG0492	ferredoxin-NADP+ reductase activity
AWM80_RS11445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWM80_RS11450	COG4862	establishment of competence for transformation
AWM80_RS11455	COG1408	metallophosphoesterase
AWM80_RS11465	COG1388	LysM domain
AWM80_RS11470	COG1266	CAAX protease self-immunity
AWM80_RS11475	COG0514	ATP-dependent DNA helicase (RecQ)
AWM80_RS11480	COG4955	Helix-turn-helix domain
AWM80_RS11485	COG1141	Ferredoxin
AWM80_RS11490	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AWM80_RS11495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWM80_RS11500	COG0710	3-dehydroquinate dehydratase activity
AWM80_RS11510	COG1595	DNA-templated transcription, initiation
AWM80_RS11515	COG5002	protein histidine kinase activity
AWM80_RS11520	COG0745	RESPONSE REGULATOR receiver
AWM80_RS11525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AWM80_RS11530	COG1333	cytochrome c biogenesis protein
AWM80_RS11535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWM80_RS11540	COG1187	pseudouridine synthase activity
AWM80_RS11545	COG0700	Nucleoside recognition
AWM80_RS11550	COG2715	membrane protein required for spore maturation
AWM80_RS11555	COG1686	Belongs to the peptidase S11 family
AWM80_RS11565	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AWM80_RS11570	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AWM80_RS11575	COG1547	Domain of unknown function (DUF309)
AWM80_RS11580	COG0456	acetyltransferase
AWM80_RS11585	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AWM80_RS11590	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWM80_RS11590	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWM80_RS11595	COG0307	riboflavin synthase, alpha
AWM80_RS11600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWM80_RS11600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWM80_RS11610	COG0681	Belongs to the peptidase S26 family
AWM80_RS11615	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AWM80_RS11640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWM80_RS11645	COG4086	secreted protein
AWM80_RS11650	COG0019	diaminopimelate decarboxylase activity
AWM80_RS11655	COG0697	spore germination
AWM80_RS11670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWM80_RS11690	COG1191	sigma factor activity
AWM80_RS11695	COG2172	sigma factor antagonist activity
AWM80_RS11700	COG1366	Belongs to the anti-sigma-factor antagonist family
AWM80_RS11705	COG1686	Belongs to the peptidase S11 family
AWM80_RS11710	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AWM80_RS11715	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AWM80_RS11720	COG4974	Belongs to the 'phage' integrase family
AWM80_RS11730	COG0735	belongs to the Fur family
AWM80_RS11735	COG1300	Membrane
AWM80_RS11745	COG0281	malic enzyme
AWM80_RS11750	COG1757	Na H antiporter
AWM80_RS11755	COG1027	Aspartate ammonia-lyase
AWM80_RS11760	COG0252	asparaginase activity
AWM80_RS11765	COG1396	sequence-specific DNA binding
AWM80_RS11770	COG1379	DNA repair
AWM80_RS11775	COG0494	nUDIX hydrolase
AWM80_RS11785	COG0667	Aldo Keto reductase
AWM80_RS11795	COG1073	alpha beta
AWM80_RS11805	COG4918	Iron-sulphur cluster biosynthesis
AWM80_RS11810	COG0456	acetyltransferase
AWM80_RS11810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AWM80_RS11815	COG2329	Antibiotic biosynthesis monooxygenase
AWM80_RS11820	COG0456	acetyltransferase
AWM80_RS11830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWM80_RS11840	COG2211	Major facilitator Superfamily
AWM80_RS11850	COG0346	lactoylglutathione lyase activity
AWM80_RS11855	COG1072	(Pantothenic acid kinase))
AWM80_RS11860	COG3048	D-serine ammonia-lyase activity
AWM80_RS11865	COG0300	oxidoreductase activity
AWM80_RS11870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWM80_RS11875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWM80_RS11880	COG4187	Peptidase family M20/M25/M40
AWM80_RS11885	COG1902	pentaerythritol trinitrate reductase activity
AWM80_RS11890	COG0596	Alpha beta hydrolase
AWM80_RS11895	COG1234	tRNA 3'-trailer cleavage
AWM80_RS11900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AWM80_RS11905	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AWM80_RS11910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWM80_RS11920	COG0706	membrane insertase activity
AWM80_RS11925	COG3361	conserved protein (COG2071)
AWM80_RS11930	COG2195	Cleaves the N-terminal amino acid of tripeptides
AWM80_RS11935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AWM80_RS11940	COG0346	lactoylglutathione lyase activity
AWM80_RS11950	COG1376	ErfK ybiS ycfS ynhG family protein
AWM80_RS11955	COG4129	membrane
AWM80_RS11960	COG1126	abc transporter atp-binding protein
AWM80_RS11965	COG0765	amino acid transport
AWM80_RS11970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWM80_RS11980	COG1597	lipid kinase activity
AWM80_RS11985	COG2814	Major facilitator Superfamily
AWM80_RS11990	COG0789	Transcriptional regulator
AWM80_RS11990	COG4978	Transcriptional regulator
AWM80_RS11995	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWM80_RS12000	COG0022	dehydrogenase e1 component
AWM80_RS12005	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWM80_RS12010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWM80_RS12015	COG3426	butyrate kinase activity
AWM80_RS12020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWM80_RS12025	COG0280	phosphate acetyltransferase
AWM80_RS12030	COG3829	transcription factor binding
AWM80_RS12030	COG3290	protein histidine kinase activity
AWM80_RS12040	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AWM80_RS12045	COG2079	MmgE PrpD family protein
AWM80_RS12050	COG0372	Belongs to the citrate synthase family
AWM80_RS12055	COG1960	acyl-CoA dehydrogenase activity
AWM80_RS12060	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWM80_RS12065	COG0183	Belongs to the thiolase family
AWM80_RS12070	COG0584	glycerophosphoryl diester phosphodiesterase
AWM80_RS12075	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWM80_RS12090	COG1902	pentaerythritol trinitrate reductase activity
AWM80_RS12100	COG0745	RESPONSE REGULATOR receiver
AWM80_RS12110	COG0750	zinc metalloprotease
AWM80_RS12115	COG0497	DNA recombination
AWM80_RS12120	COG1438	arginine binding
AWM80_RS12125	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AWM80_RS12130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AWM80_RS12135	COG0142	geranyltranstransferase activity
AWM80_RS12140	COG1722	exodeoxyribonuclease VII activity
AWM80_RS12145	COG1570	exodeoxyribonuclease VII activity
AWM80_RS12150	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AWM80_RS12155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWM80_RS12160	COG1302	Protein conserved in bacteria
AWM80_RS12165	COG0439	Biotin carboxylase
AWM80_RS12170	COG0511	ligase activity, forming carbon-carbon bonds
AWM80_RS12210	COG3854	ATPases associated with a variety of cellular activities
AWM80_RS12220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AWM80_RS12225	COG0006	proline dipeptidase activity
AWM80_RS12230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AWM80_RS12240	COG3872	metal-dependent enzyme
AWM80_RS12250	COG1752	Esterase of the alpha-beta hydrolase superfamily
AWM80_RS12255	COG1321	iron dependent repressor
AWM80_RS12260	COG0095	Lipoate-protein ligase
AWM80_RS12265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWM80_RS12270	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWM80_RS12275	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWM80_RS12280	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWM80_RS12285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWM80_RS12300	COG1396	sequence-specific DNA binding
AWM80_RS12310	COG0681	Belongs to the peptidase S26 family
AWM80_RS12335	COG4940	Competence protein ComGF
AWM80_RS12345	COG4970	Tfp pilus assembly protein FimT
AWM80_RS12350	COG4537	Required for transformation and DNA binding
AWM80_RS12355	COG1459	type II secretion system
AWM80_RS12360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AWM80_RS12370	COG0598	Magnesium transport protein CorA
AWM80_RS12375	COG1253	flavin adenine dinucleotide binding
AWM80_RS12380	COG1366	Belongs to the anti-sigma-factor antagonist family
AWM80_RS12390	COG1393	Belongs to the ArsC family
AWM80_RS12400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWM80_RS12410	COG0011	TIGRFAM Protein of
AWM80_RS12420	COG2866	Carboxypeptidase
AWM80_RS12425	COG1368	sulfuric ester hydrolase activity
AWM80_RS12430	COG1940	carbohydrate kinase activity
AWM80_RS12435	COG4483	Protein conserved in bacteria
AWM80_RS12440	COG0705	Rhomboid family
AWM80_RS12440	COG0457	Tetratricopeptide repeat
AWM80_RS12450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AWM80_RS12460	COG0438	transferase activity, transferring glycosyl groups
AWM80_RS12475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWM80_RS12480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWM80_RS12485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWM80_RS12490	COG0581	inorganic phosphate transmembrane transporter activity
AWM80_RS12495	COG0573	inorganic phosphate transmembrane transporter activity
AWM80_RS12500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AWM80_RS12505	COG0768	penicillin binding
AWM80_RS12510	COG0477	Major facilitator Superfamily
AWM80_RS12515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AWM80_RS12520	COG2839	Protein conserved in bacteria
AWM80_RS12525	COG5521	maltodextrose utilization protein MalA
AWM80_RS12535	COG1388	LysM domain
AWM80_RS12540	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AWM80_RS12545	COG4709	membrane
AWM80_RS12550	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AWM80_RS12555	COG0735	belongs to the Fur family
AWM80_RS12560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWM80_RS12570	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AWM80_RS12575	COG0513	Belongs to the DEAD box helicase family
AWM80_RS12585	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AWM80_RS12590	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AWM80_RS12595	COG2384	SAM-dependent methyltransferase
AWM80_RS12600	COG2010	Cytochrome c
AWM80_RS12605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWM80_RS12610	COG0358	DNA primase activity
AWM80_RS12615	COG1671	Belongs to the UPF0178 family
AWM80_RS12620	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AWM80_RS12625	COG0517	IMP dehydrogenase activity
AWM80_RS12630	COG0751	glycine-tRNA ligase activity
AWM80_RS12635	COG0752	glycyl-tRNA synthetase alpha subunit
AWM80_RS12640	COG1381	Involved in DNA repair and RecF pathway recombination
AWM80_RS12650	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AWM80_RS12655	COG0295	cytidine deaminase activity
AWM80_RS12660	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AWM80_RS12665	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AWM80_RS12670	COG1480	7TM receptor with intracellular HD hydrolase
AWM80_RS12680	COG1702	phosphate starvation-inducible protein PhoH
AWM80_RS12685	COG0561	phosphatase activity
AWM80_RS12700	COG4864	UPF0365 protein
AWM80_RS12705	COG1030	water channel activity
AWM80_RS12710	COG1610	YqeY-like protein
AWM80_RS12720	COG1283	sodium-dependent phosphate transmembrane transporter activity
AWM80_RS12725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWM80_RS12730	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AWM80_RS12735	COG2264	protein methyltransferase activity
AWM80_RS12740	COG0484	heat shock protein binding
AWM80_RS12745	COG0443	Heat shock 70 kDa protein
AWM80_RS12750	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AWM80_RS12755	COG1420	regulation of RNA biosynthetic process
AWM80_RS12760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWM80_RS12765	COG0481	GTPase activity
AWM80_RS12775	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWM80_RS12780	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AWM80_RS12785	COG0268	Binds directly to 16S ribosomal RNA
AWM80_RS12790	COG1466	dna polymerase III delta subunit
AWM80_RS12800	COG2333	competence protein COMEC
AWM80_RS12800	COG0658	competence protein
AWM80_RS12805	COG2131	deaminase
AWM80_RS12810	COG1555	photosystem II stabilization
AWM80_RS12810	COG1596	polysaccharide export
AWM80_RS12815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWM80_RS12820	COG2226	methyltransferase
AWM80_RS12825	COG0799	negative regulation of ribosome biogenesis
AWM80_RS12830	COG1713	HD superfamily hydrolase involved in NAD metabolism
AWM80_RS12835	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AWM80_RS12840	COG1534	Rna-binding protein
AWM80_RS12845	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWM80_RS12850	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AWM80_RS12855	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AWM80_RS12870	COG2755	lipolytic protein G-D-S-L family
AWM80_RS12875	COG3409	Peptidoglycan-binding domain 1 protein
AWM80_RS12875	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWM80_RS12880	COG0398	Pfam SNARE associated Golgi protein
AWM80_RS12885	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AWM80_RS12895	COG3209	COG3209 Rhs family protein
AWM80_RS12905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AWM80_RS12910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWM80_RS12915	COG0798	PFAM Bile acid sodium symporter
AWM80_RS12920	COG0346	lactoylglutathione lyase activity
AWM80_RS12925	COG0640	Transcriptional regulator
AWM80_RS12930	COG3403	YqcI/YcgG family
AWM80_RS12935	COG0457	Tetratricopeptide repeat
AWM80_RS12950	COG5444	nuclease activity
AWM80_RS12975	COG3409	Peptidoglycan-binding domain 1 protein
AWM80_RS12975	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWM80_RS12980	COG4824	toxin secretion phage lysis holin
AWM80_RS13010	COG3778	Protein conserved in bacteria
AWM80_RS13015	COG3299	homolog of phage Mu protein gp47
AWM80_RS13020	COG3628	GPW Gp25 family protein
AWM80_RS13030	COG4193	domain, Protein
AWM80_RS13035	COG1652	LysM domain
AWM80_RS13040	COG5280	Phage tail tape measure protein TP901
AWM80_RS13040	COG3953	SLT domain
AWM80_RS13100	COG4653	Phage capsid family
AWM80_RS13105	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AWM80_RS13115	COG2369	cell adhesion
AWM80_RS13120	COG5518	Phage portal protein
AWM80_RS13125	COG1783	phage Terminase large subunit
AWM80_RS13130	COG5484	DNA packaging
AWM80_RS13140	COG3677	Transposase
AWM80_RS13155	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AWM80_RS13170	COG1484	DNA-dependent DNA replication
AWM80_RS13175	COG3935	DnaD domain protein
AWM80_RS13180	COG3723	Recombinational DNA repair protein, rece pathway
AWM80_RS13185	COG5377	YqaJ viral recombinase family
AWM80_RS13210	COG1476	TRANSCRIPTIONal
AWM80_RS13215	COG3620	sequence-specific DNA binding
AWM80_RS13225	COG0563	adenylate kinase activity
AWM80_RS13230	COG2856	Zn peptidase
AWM80_RS13245	COG3223	Belongs to the PsiE family
AWM80_RS13250	COG0642	Histidine kinase
AWM80_RS13250	COG5002	protein histidine kinase activity
AWM80_RS13255	COG0745	RESPONSE REGULATOR receiver
AWM80_RS13260	COG2311	Membrane
AWM80_RS13270	COG0454	-acetyltransferase
AWM80_RS13275	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWM80_RS13285	COG0730	response to heat
AWM80_RS13290	COG0425	Belongs to the sulfur carrier protein TusA family
AWM80_RS13295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWM80_RS13295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWM80_RS13305	COG0425	Belongs to the sulfur carrier protein TusA family
AWM80_RS13305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWM80_RS13310	COG2210	Belongs to the sulfur carrier protein TusA family
AWM80_RS13315	COG1937	Protein conserved in bacteria
AWM80_RS13320	COG0662	Cupin 2, conserved barrel domain protein
AWM80_RS13335	COG0789	Transcriptional regulator
AWM80_RS13335	COG4978	Transcriptional regulator
AWM80_RS13340	COG2814	Major facilitator Superfamily
AWM80_RS13345	COG0456	acetyltransferase
AWM80_RS13350	COG1253	flavin adenine dinucleotide binding
AWM80_RS13360	COG0697	spore germination
AWM80_RS13365	COG0583	DNA-binding transcription factor activity
AWM80_RS13370	COG2072	flavoprotein involved in K transport
AWM80_RS13375	COG1230	cation diffusion facilitator family transporter
AWM80_RS13380	COG1942	4-Oxalocrotonate Tautomerase
AWM80_RS13385	COG0583	DNA-binding transcription factor activity
AWM80_RS13395	COG1114	Component of the transport system for branched-chain amino acids
AWM80_RS13400	COG1687	branched-chain amino acid
AWM80_RS13405	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AWM80_RS13410	COG1522	sequence-specific DNA binding
AWM80_RS13415	COG2732	(Barnase) inhibitor
AWM80_RS13420	COG2124	cytochrome p450
AWM80_RS13430	COG1335	isochorismatase
AWM80_RS13440	COG2318	DinB family
AWM80_RS13450	COG2070	2-Nitropropane dioxygenase
AWM80_RS13455	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWM80_RS13470	COG3443	Belongs to the bacterial solute-binding protein 9 family
AWM80_RS13475	COG1595	DNA-templated transcription, initiation
AWM80_RS13480	COG0667	Aldo Keto reductase
AWM80_RS13485	COG2851	Citrate transporter
AWM80_RS13490	COG0583	DNA-binding transcription factor activity
AWM80_RS13495	COG2828	Protein conserved in bacteria
AWM80_RS13500	COG3409	Peptidoglycan-binding domain 1 protein
AWM80_RS13505	COG5566	PFAM Mor transcription activator
AWM80_RS13510	COG0596	Alpha beta hydrolase
AWM80_RS13515	COG4991	sh3 domain protein
AWM80_RS13520	COG4991	sh3 domain protein
AWM80_RS13525	COG0346	lactoylglutathione lyase activity
AWM80_RS13535	COG5577	PFAM Coat F domain
AWM80_RS13540	COG1063	alcohol dehydrogenase
AWM80_RS13550	COG5577	PFAM Coat F domain
AWM80_RS13555	COG0789	Transcriptional regulator
AWM80_RS13565	COG1064	alcohol dehydrogenase
AWM80_RS13570	COG0693	protein deglycase activity
AWM80_RS13575	COG1621	beta-fructofuranosidase activity
AWM80_RS13580	COG3716	PTS system mannose fructose sorbose family IID component
AWM80_RS13585	COG3715	PTS system
AWM80_RS13590	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWM80_RS13595	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWM80_RS13600	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AWM80_RS13600	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AWM80_RS13605	COG1113	amino acid transport
AWM80_RS13610	COG1280	lysine exporter protein (LysE YggA)
AWM80_RS13615	COG1378	Sugar-specific transcriptional regulator TrmB
AWM80_RS13620	COG1595	DNA-templated transcription, initiation
AWM80_RS13630	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AWM80_RS13630	COG2755	lipolytic protein G-D-S-L family
AWM80_RS13640	COG2124	cytochrome p450
AWM80_RS13640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWM80_RS13645	COG1309	transcriptional regulator
AWM80_RS13650	COG2226	methyltransferase
AWM80_RS13660	COG2116	formate transmembrane transporter activity
AWM80_RS13665	COG5609	conserved protein (DUF2294)
AWM80_RS13670	COG3383	formate dehydrogenase (NAD+) activity
AWM80_RS13675	COG2427	Protein of unknown function (DUF1641)
AWM80_RS13685	COG0626	cystathionine gamma-synthase activity
AWM80_RS13690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWM80_RS13695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AWM80_RS13700	COG2226	methyltransferase
AWM80_RS13715	COG0768	penicillin binding
AWM80_RS13720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AWM80_RS13725	COG0572	uridine kinase
AWM80_RS13730	COG0826	peptidase U32
AWM80_RS13735	COG0826	peptidase U32
AWM80_RS13740	COG4122	O-methyltransferase activity
AWM80_RS13745	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWM80_RS13750	COG3906	Belongs to the UPF0473 family
AWM80_RS13755	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AWM80_RS13760	COG4472	Bacterial protein of unknown function (DUF965)
AWM80_RS13765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AWM80_RS13770	COG0628	permease
AWM80_RS13775	COG1126	abc transporter atp-binding protein
AWM80_RS13780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWM80_RS13785	COG0765	amino acid transport
AWM80_RS13790	COG0765	amino acid transport
AWM80_RS13805	COG3881	PFAM PRC-barrel domain
AWM80_RS13810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AWM80_RS13815	COG0457	Tetratricopeptide repeat
AWM80_RS13820	COG0482	sulfurtransferase activity
AWM80_RS13825	COG1104	cysteine desulfurase activity
AWM80_RS13830	COG1959	2 iron, 2 sulfur cluster binding
AWM80_RS13835	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AWM80_RS13840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AWM80_RS13850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AWM80_RS13855	COG0124	histidyl-tRNA synthetase
AWM80_RS13865	COG4991	sh3 domain protein
AWM80_RS13865	COG3103	Sh3 type 3 domain protein
AWM80_RS13865	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWM80_RS13870	COG1490	D-aminoacyl-tRNA deacylase activity
AWM80_RS13875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWM80_RS13880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWM80_RS13885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWM80_RS13885	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWM80_RS13890	COG5416	Lipopolysaccharide assembly protein A domain
AWM80_RS13895	COG0490	domain, Protein
AWM80_RS13900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWM80_RS13900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWM80_RS13910	COG2244	polysaccharide biosynthetic process
AWM80_RS13915	COG2323	membrane
AWM80_RS13925	COG1862	Preprotein translocase
AWM80_RS13930	COG0343	queuine tRNA-ribosyltransferase activity
AWM80_RS13935	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AWM80_RS13945	COG2255	four-way junction helicase activity
AWM80_RS13950	COG0632	four-way junction helicase activity
AWM80_RS13960	COG2814	Major facilitator Superfamily
AWM80_RS13965	COG0673	inositol 2-dehydrogenase activity
AWM80_RS13970	COG2112	serine threonine protein kinase
AWM80_RS13990	COG1115	amino acid carrier protein
AWM80_RS13995	COG0217	transcriptional regulatory protein
AWM80_RS14005	COG1388	LysM domain
AWM80_RS14010	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AWM80_RS14015	COG0157	Belongs to the NadC ModD family
AWM80_RS14020	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AWM80_RS14025	COG1104	cysteine desulfurase activity
AWM80_RS14030	COG1827	regulation of RNA biosynthetic process
AWM80_RS14035	COG0077	Prephenate dehydratase
AWM80_RS14040	COG4492	Belongs to the UPF0735 family
AWM80_RS14045	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWM80_RS14050	COG3290	protein histidine kinase activity
AWM80_RS14060	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AWM80_RS14065	COG2868	ribosomal protein
AWM80_RS14070	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AWM80_RS14075	COG1994	Peptidase M50
AWM80_RS14080	COG0739	heme binding
AWM80_RS14085	COG2894	cell division
AWM80_RS14090	COG0850	regulation of cytokinetic process
AWM80_RS14095	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AWM80_RS14105	COG1077	Cell shape determining protein MreB Mrl
AWM80_RS14110	COG2003	Belongs to the UPF0758 family
AWM80_RS14115	COG0424	maF-like protein
AWM80_RS14125	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AWM80_RS14130	COG0285	dihydrofolate synthase activity
AWM80_RS14135	COG0525	valine-tRNA ligase activity
AWM80_RS14145	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWM80_RS14150	COG1388	LysM domain
AWM80_RS14155	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWM80_RS14160	COG0113	porphobilinogen synthase activity
AWM80_RS14165	COG1587	Uroporphyrinogen-III synthase
AWM80_RS14170	COG0181	hydroxymethylbilane synthase activity
AWM80_RS14175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AWM80_RS14180	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AWM80_RS14190	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AWM80_RS14195	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AWM80_RS14200	COG1067	ATP-dependent peptidase activity
AWM80_RS14200	COG0470	DNA polymerase III
AWM80_RS14205	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AWM80_RS14210	COG0544	peptidyl-prolyl cis-trans isomerase activity
AWM80_RS14215	COG0457	Tetratricopeptide repeat
AWM80_RS14215	COG1477	protein flavinylation
AWM80_RS14220	COG0066	3-isopropylmalate dehydratase activity
AWM80_RS14225	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWM80_RS14230	COG0473	3-isopropylmalate dehydrogenase activity
AWM80_RS14235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWM80_RS14240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AWM80_RS14245	COG0440	acetolactate synthase activity
AWM80_RS14250	COG0028	Belongs to the TPP enzyme family
AWM80_RS14260	COG0454	-acetyltransferase
AWM80_RS14270	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AWM80_RS14280	COG0622	Phosphoesterase
AWM80_RS14285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AWM80_RS14290	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AWM80_RS14295	COG5401	PFAM Sporulation and spore germination
AWM80_RS14300	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWM80_RS14305	COG1846	Transcriptional regulator
AWM80_RS14310	COG2197	response regulator
AWM80_RS14315	COG0824	Thioesterase
AWM80_RS14320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AWM80_RS14325	COG1053	succinate dehydrogenase
AWM80_RS14330	COG2009	succinate dehydrogenase
AWM80_RS14340	COG1719	4-vinyl reductase, 4VR
AWM80_RS14345	COG0527	aspartate kinase activity
AWM80_RS14350	COG0322	excinuclease ABC activity
AWM80_RS14355	COG3118	belongs to the thioredoxin family
AWM80_RS14360	COG3534	alpha-L-arabinofuranosidase
AWM80_RS14365	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AWM80_RS14370	COG2086	electron transfer activity
AWM80_RS14375	COG1024	Enoyl-CoA hydratase
AWM80_RS14380	COG1309	transcriptional regulator
AWM80_RS14385	COG0318	PFAM AMP-dependent synthetase and ligase
AWM80_RS14390	COG3766	membrane
AWM80_RS14395	COG1193	negative regulation of DNA recombination
AWM80_RS14400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AWM80_RS14400	COG1796	DNA polymerase
AWM80_RS14405	COG1286	toxin biosynthetic process
AWM80_RS14410	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AWM80_RS14415	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWM80_RS14420	COG0072	phenylalanine-tRNA ligase activity
AWM80_RS14420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWM80_RS14425	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AWM80_RS14435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWM80_RS14445	COG3835	regulator
AWM80_RS14450	COG0277	FAD linked oxidase domain protein
AWM80_RS14455	COG0247	lactate metabolic process
AWM80_RS14460	COG0346	lactoylglutathione lyase activity
AWM80_RS14470	COG1966	Carbon starvation protein
AWM80_RS14475	COG3534	alpha-L-arabinofuranosidase
AWM80_RS14480	COG0395	ABC-type sugar transport system, permease component
AWM80_RS14485	COG1175	transmembrane transport
AWM80_RS14490	COG1653	transport
AWM80_RS14495	COG0371	Dehydrogenase
AWM80_RS14500	COG0647	UMP catabolic process
AWM80_RS14505	COG0235	Class ii aldolase
AWM80_RS14510	COG1069	ribulokinase activity
AWM80_RS14515	COG2160	L-arabinose isomerase activity
AWM80_RS14520	COG3507	Belongs to the glycosyl hydrolase 43 family
AWM80_RS14525	COG1363	Peptidase, m42
AWM80_RS14535	COG3326	Membrane
AWM80_RS14540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AWM80_RS14545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AWM80_RS14550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AWM80_RS14560	COG1346	cytolysis
AWM80_RS14565	COG1380	Effector of murein hydrolase LrgA
AWM80_RS14570	COG3279	Response regulator of the LytR AlgR family
AWM80_RS14575	COG3275	phosphorelay sensor kinase activity
AWM80_RS14580	COG1011	Hydrolase
AWM80_RS14585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWM80_RS14595	COG0398	Pfam SNARE associated Golgi protein
AWM80_RS14600	COG1484	DNA-dependent DNA replication
AWM80_RS14605	COG3611	Membrane attachment protein
AWM80_RS14610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWM80_RS14615	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AWM80_RS14620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWM80_RS14625	COG1733	regulation of RNA biosynthetic process
AWM80_RS14630	COG2814	Major facilitator Superfamily
AWM80_RS14635	COG0656	L-ascorbic acid biosynthetic process
AWM80_RS14640	COG0237	dephospho-CoA kinase activity
AWM80_RS14655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AWM80_RS14660	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWM80_RS14660	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWM80_RS14665	COG5002	protein histidine kinase activity
AWM80_RS14670	COG0745	RESPONSE REGULATOR receiver
AWM80_RS14675	COG0039	L-malate dehydrogenase activity
AWM80_RS14680	COG0538	isocitrate dehydrogenase activity
AWM80_RS14685	COG0372	Belongs to the citrate synthase family
AWM80_RS14690	COG2707	UPF0756 membrane protein
AWM80_RS14695	COG0628	permease
AWM80_RS14700	COG3030	protein affecting phage T7 exclusion by the F plasmid
AWM80_RS14705	COG0469	pyruvate kinase activity
AWM80_RS14710	COG0205	6-phosphofructokinase activity
AWM80_RS14715	COG0825	malonyl-CoA metabolic process
AWM80_RS14720	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AWM80_RS14725	COG0281	malic enzyme
AWM80_RS14730	COG0587	DNA-directed DNA polymerase activity
AWM80_RS14750	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AWM80_RS14760	COG4109	DRTGG domain
AWM80_RS14770	COG0730	response to heat
AWM80_RS14775	COG1473	amidohydrolase
AWM80_RS14780	COG0196	riboflavin kinase activity
AWM80_RS14785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWM80_RS14790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AWM80_RS14795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWM80_RS14800	COG1126	abc transporter atp-binding protein
AWM80_RS14805	COG0765	amino acid transport
AWM80_RS14810	COG0765	amino acid transport
AWM80_RS14815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWM80_RS14820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWM80_RS14825	COG0454	-acetyltransferase
AWM80_RS14830	COG0583	DNA-binding transcription factor activity
AWM80_RS14835	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AWM80_RS14840	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS14850	COG0165	Argininosuccinate lyase
AWM80_RS14855	COG0137	argininosuccinate synthase activity
AWM80_RS14860	COG0521	Mo-molybdopterin cofactor biosynthetic process
AWM80_RS14865	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AWM80_RS14870	COG0827	DNA restriction-modification system
AWM80_RS14875	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AWM80_RS14880	COG3874	Sporulation protein YtfJ
AWM80_RS14890	COG1714	RDD family
AWM80_RS14895	COG0616	signal peptide processing
AWM80_RS14900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWM80_RS14905	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AWM80_RS14910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWM80_RS14920	COG0301	tRNA thio-modification
AWM80_RS14925	COG1104	cysteine desulfurase activity
AWM80_RS14930	COG1114	Component of the transport system for branched-chain amino acids
AWM80_RS14935	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AWM80_RS14940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AWM80_RS14945	COG1309	transcriptional regulator
AWM80_RS14950	COG1956	GAF domain-containing protein
AWM80_RS14955	COG2199	diguanylate cyclase activity
AWM80_RS14955	COG2203	Gaf domain
AWM80_RS14960	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWM80_RS14970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWM80_RS14975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWM80_RS14980	COG0454	-acetyltransferase
AWM80_RS14985	COG0517	IMP dehydrogenase activity
AWM80_RS14990	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWM80_RS14995	COG1360	Flagellar Motor Protein
AWM80_RS15000	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AWM80_RS15005	COG1609	Transcriptional regulator
AWM80_RS15010	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AWM80_RS15010	COG1605	Chorismate mutase
AWM80_RS15015	COG3118	belongs to the thioredoxin family
AWM80_RS15020	COG4980	gas vesicle protein
AWM80_RS15025	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AWM80_RS15030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AWM80_RS15035	COG1674	ftsk spoiiie
AWM80_RS15040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWM80_RS15045	COG4848	Belongs to the UPF0354 family
AWM80_RS15050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWM80_RS15060	COG1363	Peptidase, m42
AWM80_RS15065	COG5584	Small secreted protein
AWM80_RS15070	COG0281	malic enzyme
AWM80_RS15075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWM80_RS15080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AWM80_RS15090	COG0510	thiamine kinase activity
AWM80_RS15095	COG1523	belongs to the glycosyl hydrolase 13 family
AWM80_RS15100	COG1597	lipid kinase activity
AWM80_RS15110	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AWM80_RS15115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWM80_RS15120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWM80_RS15125	COG2252	PERMEase
AWM80_RS15130	COG4473	ABC transporter
AWM80_RS15135	COG1131	(ABC) transporter
AWM80_RS15140	COG1349	DNA-binding transcription factor activity
AWM80_RS15145	COG1187	pseudouridine synthase activity
AWM80_RS15150	COG2244	polysaccharide biosynthetic process
AWM80_RS15155	COG2081	HI0933 family
AWM80_RS15160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AWM80_RS15170	COG5578	integral membrane protein
AWM80_RS15175	COG0673	inositol 2-dehydrogenase activity
AWM80_RS15180	COG1653	transport
AWM80_RS15185	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AWM80_RS15190	COG4209	transmembrane transport
AWM80_RS15195	COG2207	Transcriptional regulator
AWM80_RS15200	COG1653	transport
AWM80_RS15205	COG0395	ABC-type sugar transport system, permease component
AWM80_RS15210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWM80_RS15215	COG2124	cytochrome p450
AWM80_RS15220	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AWM80_RS15225	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AWM80_RS15230	COG0156	8-amino-7-oxononanoate synthase activity
AWM80_RS15235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AWM80_RS15240	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
AWM80_RS15245	COG1073	alpha beta
AWM80_RS15250	COG1609	Transcriptional regulator
AWM80_RS15255	COG1653	transport
AWM80_RS15260	COG1175	transmembrane transport
AWM80_RS15265	COG0395	ABC-type sugar transport system, permease component
AWM80_RS15270	COG1486	melibiose metabolic process
AWM80_RS15275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWM80_RS15280	COG0495	leucyl-tRNA aminoacylation
AWM80_RS15290	COG2202	Pas domain
AWM80_RS15290	COG1366	Belongs to the anti-sigma-factor antagonist family
AWM80_RS15295	COG2814	Major facilitator Superfamily
AWM80_RS15300	COG2433	Pfam Transposase IS66
AWM80_RS15305	COG0577	efflux transmembrane transporter activity
AWM80_RS15310	COG1136	(ABC) transporter
AWM80_RS15315	COG2205	protein histidine kinase activity
AWM80_RS15320	COG0745	RESPONSE REGULATOR receiver
AWM80_RS15325	COG0577	efflux transmembrane transporter activity
AWM80_RS15330	COG1136	(ABC) transporter
AWM80_RS15345	COG1131	(ABC) transporter
AWM80_RS15350	COG1725	Transcriptional regulator
AWM80_RS15365	COG1242	4 iron, 4 sulfur cluster binding
AWM80_RS15370	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AWM80_RS15380	COG2267	carboxylic ester hydrolase activity
AWM80_RS15385	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AWM80_RS15390	COG1113	amino acid transport
AWM80_RS15395	COG0367	asparagine synthase
AWM80_RS15400	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AWM80_RS15405	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AWM80_RS15415	COG1506	peptidase
AWM80_RS15420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWM80_RS15425	COG1116	anion transmembrane transporter activity
AWM80_RS15430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWM80_RS15435	COG0494	nUDIX hydrolase
AWM80_RS15440	COG4824	toxin secretion phage lysis holin
AWM80_RS15445	COG0783	Belongs to the Dps family
AWM80_RS15460	COG1854	S-ribosylhomocysteine lyase activity
AWM80_RS15465	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AWM80_RS15470	COG0288	reversible hydration of carbon dioxide
AWM80_RS15475	COG0254	rRNA binding
AWM80_RS15480	COG1271	oxidase subunit
AWM80_RS15485	COG1294	oxidase, subunit
AWM80_RS15495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWM80_RS15500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWM80_RS15500	COG1321	iron dependent repressor
AWM80_RS15505	COG1121	(ABC) transporter
AWM80_RS15510	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWM80_RS15515	COG4948	Mandelate Racemase Muconate Lactonizing
AWM80_RS15520	COG0318	PFAM AMP-dependent synthetase and ligase
AWM80_RS15525	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AWM80_RS15530	COG0596	Alpha beta hydrolase
AWM80_RS15535	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AWM80_RS15540	COG1169	isochorismate synthase
AWM80_RS15545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AWM80_RS15550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AWM80_RS15555	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AWM80_RS15560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWM80_RS15565	COG0438	transferase activity, transferring glycosyl groups
AWM80_RS15575	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWM80_RS15580	COG0438	transferase activity, transferring glycosyl groups
AWM80_RS15585	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWM80_RS15590	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AWM80_RS15595	COG0058	SHG alpha-glucan phosphorylase activity
AWM80_RS15600	COG0297	glycogen (starch) synthase activity
AWM80_RS15605	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWM80_RS15610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWM80_RS15615	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AWM80_RS15745	COG3859	Proton-coupled thiamine transporter YuaJ
AWM80_RS15750	COG1247	-acetyltransferase
AWM80_RS15755	COG2268	Band 7 protein
AWM80_RS15760	COG1585	Membrane protein implicated in regulation of membrane protease activity
AWM80_RS15765	COG2318	DinB family
AWM80_RS15775	COG1454	alcohol dehydrogenase
AWM80_RS15785	COG1510	regulation of RNA biosynthetic process
AWM80_RS15795	COG0569	domain protein
AWM80_RS15800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWM80_RS15805	COG4682	membrane
AWM80_RS15810	COG1705	Flagellar rod assembly protein muramidase FlgJ
AWM80_RS15815	COG0477	Major facilitator Superfamily
AWM80_RS15820	COG5553	Cysteine dioxygenase type I
AWM80_RS15830	COG1968	undecaprenyl-diphosphatase activity
AWM80_RS15835	COG0628	permease
AWM80_RS15840	COG0673	inositol 2-dehydrogenase activity
AWM80_RS15845	COG4806	L-rhamnose isomerase
AWM80_RS15850	COG3254	rhamnose metabolic process
AWM80_RS15855	COG1070	Carbohydrate kinase
AWM80_RS15860	COG1349	DNA-binding transcription factor activity
AWM80_RS15865	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS15865	COG3347	Dehydrogenase
AWM80_RS15870	COG0840	transmembrane signaling receptor activity
AWM80_RS15875	COG0840	transmembrane signaling receptor activity
AWM80_RS15880	COG0840	transmembrane signaling receptor activity
AWM80_RS15885	COG0840	transmembrane signaling receptor activity
AWM80_RS15900	COG0432	Pfam Uncharacterised protein family UPF0047
AWM80_RS15905	COG0366	Alpha amylase catalytic
AWM80_RS15910	COG1253	flavin adenine dinucleotide binding
AWM80_RS15915	COG2738	Putative neutral zinc metallopeptidase
AWM80_RS15930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AWM80_RS15945	COG0166	Belongs to the GPI family
AWM80_RS15950	COG1979	alcohol dehydrogenase
AWM80_RS15955	COG1979	alcohol dehydrogenase
AWM80_RS15960	COG2155	Conserved Protein
AWM80_RS15965	COG1098	S1 RNA binding domain
AWM80_RS15970	COG0436	Aminotransferase
AWM80_RS15975	COG1522	sequence-specific DNA binding
AWM80_RS15980	COG2267	carboxylic ester hydrolase activity
AWM80_RS15990	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AWM80_RS15995	COG2205	protein histidine kinase activity
AWM80_RS16005	COG5018	Exonuclease
AWM80_RS16015	COG2814	Major facilitator Superfamily
AWM80_RS16020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWM80_RS16025	COG3011	Protein conserved in bacteria
AWM80_RS16035	COG3290	protein histidine kinase activity
AWM80_RS16040	COG4565	transcriptional regulatory protein
AWM80_RS16045	COG1744	ABC transporter substrate-binding protein PnrA-like
AWM80_RS16050	COG3845	ABC transporter
AWM80_RS16055	COG4603	Belongs to the binding-protein-dependent transport system permease family
AWM80_RS16060	COG1079	Belongs to the binding-protein-dependent transport system permease family
AWM80_RS16065	COG3493	citrate carrier protein
AWM80_RS16075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWM80_RS16075	COG2111	Na H antiporter
AWM80_RS16080	COG2111	Na H antiporter
AWM80_RS16085	COG1006	Multisubunit Na H antiporter MnhC subunit
AWM80_RS16090	COG0651	ATP synthesis coupled electron transport
AWM80_RS16095	COG1863	multisubunit Na H antiporter MnhE subunit
AWM80_RS16100	COG2212	antiporter activity
AWM80_RS16105	COG1320	monovalent cation:proton antiporter activity
AWM80_RS16110	COG2050	protein possibly involved in aromatic compounds catabolism
AWM80_RS16115	COG2197	response regulator
AWM80_RS16120	COG4585	Histidine kinase
AWM80_RS16130	COG0142	geranyltranstransferase activity
AWM80_RS16145	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AWM80_RS16150	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AWM80_RS16155	COG1335	isochorismatase
AWM80_RS16160	COG5506	Protein of unknown function (DUF1694)
AWM80_RS16175	COG0628	permease
AWM80_RS16190	COG1418	mRNA catabolic process
AWM80_RS16195	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS16205	COG1511	domain protein
AWM80_RS16210	COG0433	COG0433 Predicted ATPase
AWM80_RS16210	COG1674	ftsk spoiiie
AWM80_RS16215	COG4499	WXG100 protein secretion system (Wss), protein YukC
AWM80_RS16220	COG5417	Belongs to the EsaB family
AWM80_RS16225	COG4842	Belongs to the WXG100 family
AWM80_RS16230	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AWM80_RS16230	COG2508	Transcriptional regulator
AWM80_RS16235	COG0686	Belongs to the AlaDH PNT family
AWM80_RS16240	COG5634	Uncharacterized conserved protein (DUF2278)
AWM80_RS16245	COG3251	PFAM MbtH domain protein
AWM80_RS16250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWM80_RS16255	COG3433	isochorismatase activity
AWM80_RS16255	COG1535	isochorismatase
AWM80_RS16260	COG1021	2,3-dihydroxybenzoate-AMP ligase
AWM80_RS16265	COG1169	isochorismate synthase
AWM80_RS16270	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS16275	COG2819	hydrolase of the alpha beta superfamily
AWM80_RS16280	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AWM80_RS16285	COG1268	BioY protein
AWM80_RS16290	COG2056	Na+-H+ antiporter family
AWM80_RS16295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AWM80_RS16300	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AWM80_RS16305	COG3584	3D domain protein
AWM80_RS16320	COG1252	NADH dehydrogenase
AWM80_RS16325	COG0492	ferredoxin-NADP+ reductase activity
AWM80_RS16335	COG0516	GMP reductase activity
AWM80_RS16340	COG2808	Putative FMN-binding domain
AWM80_RS16345	COG0456	acetyltransferase
AWM80_RS16350	COG0316	Belongs to the HesB IscA family
AWM80_RS16355	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AWM80_RS16360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWM80_RS16365	COG4844	belongs to the
AWM80_RS16370	COG1252	NADH dehydrogenase
AWM80_RS16375	COG4837	Protein of unknown function (DUF1462)
AWM80_RS16380	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AWM80_RS16385	COG4946	Tricorn protease homolog
AWM80_RS16385	COG1506	peptidase
AWM80_RS16385	COG0823	Involved in the tonB-independent uptake of proteins
AWM80_RS16390	COG0083	homoserine kinase activity
AWM80_RS16400	COG0460	homoserine dehydrogenase
AWM80_RS16405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWM80_RS16410	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AWM80_RS16415	COG0647	UMP catabolic process
AWM80_RS16420	COG2445	Protein of unknown function DUF86
AWM80_RS16425	COG4470	Protein conserved in bacteria
AWM80_RS16435	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWM80_RS16440	COG0739	heme binding
AWM80_RS16450	COG3377	Domain of unknown function (DUF1805)
AWM80_RS16455	COG0737	Belongs to the 5'-nucleotidase family
AWM80_RS16460	COG0730	response to heat
AWM80_RS16465	COG1801	Protein of unknown function DUF72
AWM80_RS16475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWM80_RS16480	COG2508	Transcriptional regulator
AWM80_RS16485	COG2233	PERMEase
AWM80_RS16490	COG2233	PERMEase
AWM80_RS16495	COG3648	Uricase
AWM80_RS16495	COG3195	allantoin biosynthetic process
AWM80_RS16500	COG2351	hydroxyisourate hydrolase activity
AWM80_RS16510	COG2080	2 iron, 2 sulfur cluster binding
AWM80_RS16520	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AWM80_RS16525	COG2068	MobA-Related Protein
AWM80_RS16530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AWM80_RS16535	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AWM80_RS16540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWM80_RS16550	COG2356	endonuclease I
AWM80_RS16555	COG3842	ATPase activity
AWM80_RS16560	COG2188	Transcriptional regulator
AWM80_RS16565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWM80_RS16570	COG0395	ABC-type sugar transport system, permease component
AWM80_RS16575	COG1175	transmembrane transport
AWM80_RS16580	COG1653	transport
AWM80_RS16585	COG2222	sugar isomerase
AWM80_RS16590	COG0322	excinuclease ABC activity
AWM80_RS16595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWM80_RS16610	COG0346	lactoylglutathione lyase activity
AWM80_RS16615	COG0640	Transcriptional regulator
AWM80_RS16620	COG0719	Fe-S assembly protein
AWM80_RS16625	COG0822	iron-sulfur transferase activity
AWM80_RS16630	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWM80_RS16635	COG0719	Fe-S assembly protein
AWM80_RS16640	COG0396	ATPase activity
AWM80_RS16650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AWM80_RS16655	COG1464	Belongs to the NlpA lipoprotein family
AWM80_RS16660	COG2011	ABC-type metal ion transport system permease component
AWM80_RS16665	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWM80_RS16675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWM80_RS16680	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AWM80_RS16690	COG0509	glycine decarboxylation via glycine cleavage system
AWM80_RS16695	COG1393	Belongs to the ArsC family
AWM80_RS16700	COG1960	acyl-CoA dehydrogenase activity
AWM80_RS16705	COG0183	Belongs to the thiolase family
AWM80_RS16710	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWM80_RS16710	COG1024	Enoyl-CoA hydratase
AWM80_RS16720	COG0506	proline dehydrogenase activity
AWM80_RS16730	COG5577	PFAM Coat F domain
AWM80_RS16735	COG1846	Transcriptional regulator
AWM80_RS16740	COG0477	Major facilitator Superfamily
AWM80_RS16745	COG1942	4-Oxalocrotonate Tautomerase
AWM80_RS16750	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS16755	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS16760	COG0583	DNA-binding transcription factor activity
AWM80_RS16770	COG1120	ATPase activity
AWM80_RS16790	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS16795	COG0783	Belongs to the Dps family
AWM80_RS16800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWM80_RS16805	COG0745	RESPONSE REGULATOR receiver
AWM80_RS16810	COG2205	protein histidine kinase activity
AWM80_RS16810	COG2770	Histidine kinase
AWM80_RS16820	COG1309	transcriptional regulator
AWM80_RS16825	COG0114	fumarate hydratase activity
AWM80_RS16835	COG0697	spore germination
AWM80_RS16840	COG0814	amino acid
AWM80_RS16850	COG2197	response regulator
AWM80_RS16855	COG4585	Histidine kinase
AWM80_RS16860	COG4758	membrane
AWM80_RS16865	COG3595	metallopeptidase activity
AWM80_RS16870	COG1842	Phage shock protein A
AWM80_RS16875	COG4758	membrane
AWM80_RS16880	COG2814	Major facilitator Superfamily
AWM80_RS16885	COG2096	Adenosyltransferase
AWM80_RS16890	COG1120	ATPase activity
AWM80_RS16895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWM80_RS16900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWM80_RS16905	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS16910	COG3386	PFAM SMP-30 Gluconolaconase
AWM80_RS16915	COG2205	protein histidine kinase activity
AWM80_RS16920	COG0745	RESPONSE REGULATOR receiver
AWM80_RS16930	COG1191	sigma factor activity
AWM80_RS16940	COG2140	Oxalate decarboxylase
AWM80_RS16950	COG0577	efflux transmembrane transporter activity
AWM80_RS16955	COG1136	(ABC) transporter
AWM80_RS16960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWM80_RS16965	COG1120	ATPase activity
AWM80_RS16970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWM80_RS16975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWM80_RS16980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWM80_RS16990	COG0531	amino acid
AWM80_RS17000	COG1988	membrane-bound metal-dependent
AWM80_RS17005	COG1368	sulfuric ester hydrolase activity
AWM80_RS17010	COG1910	domain protein
AWM80_RS17015	COG0725	ABC transporter, periplasmic molybdate-binding protein
AWM80_RS17020	COG4149	molybdate abc transporter
AWM80_RS17025	COG0656	L-ascorbic acid biosynthetic process
AWM80_RS17035	COG0025	NhaP-type Na H and K H
AWM80_RS17040	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWM80_RS17045	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWM80_RS17050	COG3973	AAA domain
AWM80_RS17055	COG2860	membrane
AWM80_RS17060	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AWM80_RS17065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AWM80_RS17070	COG2217	Heavy metal translocating P-type atpase
AWM80_RS17075	COG2217	Heavy metal translocating P-type atpase
AWM80_RS17080	COG2608	mercury ion transmembrane transporter activity
AWM80_RS17085	COG1937	Protein conserved in bacteria
AWM80_RS17090	COG0673	inositol 2-dehydrogenase activity
AWM80_RS17095	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AWM80_RS17100	COG1289	transmembrane transporter activity
AWM80_RS17110	COG2076	Multidrug Resistance protein
AWM80_RS17115	COG1309	transcriptional regulator
AWM80_RS17120	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS17130	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AWM80_RS17135	COG0557	exoribonuclease II activity
AWM80_RS17140	COG1647	Serine aminopeptidase, S33
AWM80_RS17145	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWM80_RS17150	COG0596	Alpha beta hydrolase
AWM80_RS17155	COG1476	TRANSCRIPTIONal
AWM80_RS17160	COG1396	sequence-specific DNA binding
AWM80_RS17165	COG1396	sequence-specific DNA binding
AWM80_RS17170	COG1733	regulation of RNA biosynthetic process
AWM80_RS17175	COG0840	transmembrane signaling receptor activity
AWM80_RS17180	COG1174	glycine betaine transport
AWM80_RS17185	COG1732	Glycine betaine
AWM80_RS17190	COG1174	glycine betaine transport
AWM80_RS17195	COG0517	IMP dehydrogenase activity
AWM80_RS17195	COG1125	glycine betaine transport
AWM80_RS17200	COG1510	regulation of RNA biosynthetic process
AWM80_RS17220	COG5658	integral membrane protein
AWM80_RS17225	COG0640	Transcriptional regulator
AWM80_RS17230	COG1174	glycine betaine transport
AWM80_RS17235	COG1732	Glycine betaine
AWM80_RS17240	COG1174	glycine betaine transport
AWM80_RS17245	COG0517	IMP dehydrogenase activity
AWM80_RS17245	COG1125	glycine betaine transport
AWM80_RS17250	COG1510	regulation of RNA biosynthetic process
AWM80_RS17255	COG2095	MarC family integral membrane protein
AWM80_RS17265	COG3064	Membrane
AWM80_RS17270	COG4640	response to antibiotic
AWM80_RS17275	COG0456	acetyltransferase
AWM80_RS17280	COG0148	phosphopyruvate hydratase activity
AWM80_RS17285	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AWM80_RS17290	COG0149	triose-phosphate isomerase activity
AWM80_RS17295	COG0126	phosphoglycerate kinase activity
AWM80_RS17305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWM80_RS17310	COG2390	Transcriptional regulator
AWM80_RS17315	COG2814	Major facilitator Superfamily
AWM80_RS17320	COG1609	Transcriptional regulator
AWM80_RS17325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWM80_RS17330	COG0583	DNA-binding transcription factor activity
AWM80_RS17335	COG0697	spore germination
AWM80_RS17340	COG1113	amino acid transport
AWM80_RS17345	COG3858	chitin binding
AWM80_RS17350	COG1556	Lactate utilization protein
AWM80_RS17355	COG1139	Iron-sulfur cluster binding protein
AWM80_RS17360	COG0247	lactate metabolic process
AWM80_RS17365	COG2197	response regulator
AWM80_RS17370	COG4585	Histidine kinase
AWM80_RS17375	COG0842	Transport permease protein
AWM80_RS17380	COG1131	(ABC) transporter
AWM80_RS17385	COG0596	Alpha beta hydrolase
AWM80_RS17390	COG2208	phosphoserine phosphatase activity
AWM80_RS17395	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AWM80_RS17400	COG1874	Beta-galactosidase
AWM80_RS17405	COG3833	ABC-type maltose transport systems, permease component
AWM80_RS17410	COG1175	transmembrane transport
AWM80_RS17415	COG2182	Extracellular solute-binding protein
AWM80_RS17420	COG1609	Transcriptional regulator
AWM80_RS17425	COG2186	Transcriptional regulator
AWM80_RS17430	COG1620	l-lactate permease
AWM80_RS17435	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AWM80_RS17445	COG5039	Polysaccharide pyruvyl transferase
AWM80_RS17450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AWM80_RS17455	COG0110	maltose O-acetyltransferase activity
AWM80_RS17460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AWM80_RS17465	COG2244	polysaccharide biosynthetic process
AWM80_RS17470	COG1216	Glycosyl transferase, family 2
AWM80_RS17475	COG5039	Polysaccharide pyruvyl transferase
AWM80_RS17480	COG1216	Glycosyl transferase, family 2
AWM80_RS17490	COG0438	transferase activity, transferring glycosyl groups
AWM80_RS17495	COG1215	transferase activity, transferring glycosyl groups
AWM80_RS17500	COG0438	transferase activity, transferring glycosyl groups
AWM80_RS17505	COG1086	Polysaccharide biosynthesis protein
AWM80_RS17510	COG0489	protein tyrosine kinase activity
AWM80_RS17515	COG3944	biosynthesis protein
AWM80_RS17520	COG1396	sequence-specific DNA binding
AWM80_RS17525	COG2272	Belongs to the type-B carboxylesterase lipase family
AWM80_RS17535	COG3479	Phenolic acid decarboxylase
AWM80_RS17545	COG1794	racemase activity, acting on amino acids and derivatives
AWM80_RS17550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AWM80_RS17555	COG1621	beta-fructofuranosidase activity
AWM80_RS17560	COG1621	beta-fructofuranosidase activity
AWM80_RS17565	COG0531	amino acid
AWM80_RS17570	COG1309	transcriptional regulator
AWM80_RS17575	COG2076	Multidrug Resistance protein
AWM80_RS17580	COG2076	Multidrug Resistance protein
AWM80_RS17590	COG0277	FAD linked oxidase domain protein
AWM80_RS17595	COG3621	Patatin-like phospholipase
AWM80_RS17605	COG0740	serine-type endopeptidase activity
AWM80_RS17610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWM80_RS17615	COG0366	Alpha amylase catalytic
AWM80_RS17620	COG1554	hydrolase, family 65, central catalytic
AWM80_RS17625	COG5521	maltodextrose utilization protein MalA
AWM80_RS17630	COG3833	ABC-type maltose transport systems, permease component
AWM80_RS17635	COG1175	transmembrane transport
AWM80_RS17640	COG2182	Extracellular solute-binding protein
AWM80_RS17645	COG0366	Alpha amylase catalytic
AWM80_RS17650	COG1609	Transcriptional regulator
AWM80_RS17655	COG1611	Belongs to the LOG family
AWM80_RS17660	COG1694	Mazg nucleotide pyrophosphohydrolase
AWM80_RS17665	COG0659	secondary active sulfate transmembrane transporter activity
AWM80_RS17670	COG0288	reversible hydration of carbon dioxide
AWM80_RS17675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWM80_RS17680	COG0577	efflux transmembrane transporter activity
AWM80_RS17685	COG1136	(ABC) transporter
AWM80_RS17690	COG5002	protein histidine kinase activity
AWM80_RS17695	COG0745	RESPONSE REGULATOR receiver
AWM80_RS17705	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AWM80_RS17710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWM80_RS17715	COG1481	regulation of sporulation
AWM80_RS17720	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AWM80_RS17725	COG1660	Displays ATPase and GTPase activities
AWM80_RS17730	COG1051	belongs to the nudix hydrolase family
AWM80_RS17735	COG0492	ferredoxin-NADP+ reductase activity
AWM80_RS17740	COG3883	PFAM NLP P60 protein
AWM80_RS17740	COG0791	NLP P60 protein
AWM80_RS17745	COG0457	Tetratricopeptide repeat
AWM80_RS17750	COG1132	(ABC) transporter
AWM80_RS17770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AWM80_RS17770	COG0140	phosphoribosyl-ATP diphosphatase activity
AWM80_RS17775	COG0107	imidazoleglycerol-phosphate synthase activity
AWM80_RS17780	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AWM80_RS17785	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AWM80_RS17790	COG0131	Imidazoleglycerol-phosphate dehydratase
AWM80_RS17795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AWM80_RS17800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AWM80_RS17805	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AWM80_RS17810	COG4990	cell redox homeostasis
AWM80_RS17815	COG5297	Belongs to the glycosyl hydrolase family 6
AWM80_RS17820	COG0110	maltose O-acetyltransferase activity
AWM80_RS17825	COG0546	phosphoglycolate phosphatase activity
AWM80_RS17830	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AWM80_RS17835	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AWM80_RS17840	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AWM80_RS17845	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AWM80_RS17850	COG0363	glucosamine-6-phosphate deaminase activity
AWM80_RS17855	COG2188	Transcriptional regulator
AWM80_RS17860	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AWM80_RS17865	COG1846	Transcriptional regulator
AWM80_RS17870	COG2124	cytochrome p450
AWM80_RS17880	COG1846	Transcriptional regulator
AWM80_RS17885	COG2814	Major facilitator Superfamily
AWM80_RS17890	COG1950	PFAM Membrane protein of
AWM80_RS17895	COG1983	PspC domain protein
AWM80_RS17900	COG3595	metallopeptidase activity
AWM80_RS17915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AWM80_RS17920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AWM80_RS17925	COG0556	nucleotide-excision repair
AWM80_RS17930	COG4897	Protein conserved in bacteria
AWM80_RS17935	COG3848	Pyruvate phosphate dikinase
AWM80_RS17935	COG0574	Belongs to the PEP-utilizing enzyme family
AWM80_RS17940	COG1309	transcriptional regulator
AWM80_RS17945	COG2814	Major facilitator Superfamily
AWM80_RS17950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWM80_RS17960	COG3409	Peptidoglycan-binding domain 1 protein
AWM80_RS17960	COG0793	Belongs to the peptidase S41A family
AWM80_RS17965	COG2177	Part of the ABC transporter FtsEX involved in
AWM80_RS17970	COG2884	Cell division ATP-binding protein ftsE
AWM80_RS17975	COG2010	Cytochrome c
AWM80_RS17980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWM80_RS17985	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AWM80_RS17990	COG0653	protein targeting
AWM80_RS17995	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AWM80_RS18010	COG1516	flagellar protein fliS
AWM80_RS18015	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AWM80_RS18020	COG1334	flagellar protein FlaG
AWM80_RS18025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AWM80_RS18030	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AWM80_RS18035	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AWM80_RS18045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AWM80_RS18050	COG4786	Flagellar basal body rod
AWM80_RS18050	COG1256	bacterial-type flagellum assembly
AWM80_RS18055	COG3418	PFAM FlgN family protein
AWM80_RS18060	COG2747	anti-sigma28 factor FlgM
AWM80_RS18070	COG1040	competence protein
AWM80_RS18080	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AWM80_RS18085	COG1307	EDD domain protein, DegV family
AWM80_RS18090	COG2197	response regulator
AWM80_RS18095	COG4585	Histidine kinase
AWM80_RS18100	COG1739	Uncharacterized protein family UPF0029
AWM80_RS18105	COG1316	TRANSCRIPTIONal
AWM80_RS18110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWM80_RS18115	COG0438	transferase activity, transferring glycosyl groups
AWM80_RS18120	COG1215	transferase activity, transferring glycosyl groups
AWM80_RS18125	COG3206	protein involved in exopolysaccharide biosynthesis
AWM80_RS18130	COG3307	-O-antigen
AWM80_RS18135	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AWM80_RS18140	COG0438	transferase activity, transferring glycosyl groups
AWM80_RS18140	COG0297	glycogen (starch) synthase activity
AWM80_RS18145	COG2244	polysaccharide biosynthetic process
AWM80_RS18150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AWM80_RS18160	COG2247	cell wall binding repeat
AWM80_RS18160	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWM80_RS18165	COG2385	sporulation resulting in formation of a cellular spore
AWM80_RS18165	COG2247	cell wall binding repeat
AWM80_RS18175	COG1316	TRANSCRIPTIONal
AWM80_RS18180	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AWM80_RS18185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AWM80_RS18190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWM80_RS18190	COG1215	transferase activity, transferring glycosyl groups
AWM80_RS18195	COG0463	Glycosyl transferase, family 2
AWM80_RS18210	COG1134	teichoic acid transport
AWM80_RS18215	COG1682	transport, permease protein
AWM80_RS18220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWM80_RS18225	COG0438	transferase activity, transferring glycosyl groups
AWM80_RS18230	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AWM80_RS18235	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AWM80_RS18240	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWM80_RS18250	COG4193	domain, Protein
AWM80_RS18255	COG1482	cell wall glycoprotein biosynthetic process
AWM80_RS18265	COG0697	spore germination
AWM80_RS18270	COG0814	amino acid
AWM80_RS18280	COG2814	Major facilitator Superfamily
AWM80_RS18285	COG1316	TRANSCRIPTIONal
AWM80_RS18290	COG0561	phosphatase activity
AWM80_RS18295	COG0791	NLP P60 protein
AWM80_RS18305	COG2843	Capsule synthesis protein
AWM80_RS18315	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AWM80_RS18320	COG1609	Transcriptional regulator
AWM80_RS18325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWM80_RS18330	COG1869	D-ribose catabolic process
AWM80_RS18335	COG1129	ABC transporter
AWM80_RS18340	COG1172	Belongs to the binding-protein-dependent transport system permease family
AWM80_RS18345	COG1879	ABC-type sugar transport system periplasmic component
AWM80_RS18350	COG3103	Sh3 type 3 domain protein
AWM80_RS18360	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWM80_RS18365	COG3527	Alpha-acetolactate decarboxylase
AWM80_RS18370	COG0028	Belongs to the TPP enzyme family
AWM80_RS18375	COG0583	DNA-binding transcription factor activity
AWM80_RS18380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AWM80_RS18395	COG5337	Spore coat protein CotH
AWM80_RS18405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWM80_RS18415	COG0405	Gamma-glutamyltransferase
AWM80_RS18420	COG1522	sequence-specific DNA binding
AWM80_RS18425	COG2059	Chromate
AWM80_RS18430	COG2059	Chromate
AWM80_RS18440	COG0655	NAD(P)H dehydrogenase (quinone) activity
AWM80_RS18445	COG0583	DNA-binding transcription factor activity
AWM80_RS18450	COG1515	deoxyribonuclease V activity
AWM80_RS18455	COG2849	repeat protein
AWM80_RS18460	COG5444	nuclease activity
AWM80_RS18475	COG3878	Protein conserved in bacteria
AWM80_RS18480	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AWM80_RS18485	COG4464	protein tyrosine phosphatase activity
AWM80_RS18490	COG0489	protein tyrosine kinase activity
AWM80_RS18495	COG3944	biosynthesis protein
AWM80_RS18505	COG4715	Zinc finger, swim domain protein
AWM80_RS18510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWM80_RS18515	COG0561	phosphatase activity
AWM80_RS18520	COG1349	DNA-binding transcription factor activity
AWM80_RS18525	COG0629	single-stranded DNA binding
AWM80_RS18540	COG3764	Sortase (surface protein transpeptidase)
AWM80_RS18545	COG0745	RESPONSE REGULATOR receiver
AWM80_RS18545	COG2972	Histidine kinase
AWM80_RS18550	COG1970	mechanosensitive ion channel activity
AWM80_RS18555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWM80_RS18560	COG0457	Tetratricopeptide repeat
AWM80_RS18565	COG4786	Flagellar basal body rod
AWM80_RS18570	COG4786	Flagellar basal body rod
AWM80_RS18575	COG1077	Cell shape determining protein MreB Mrl
AWM80_RS18580	COG1609	Transcriptional regulator
AWM80_RS18585	COG1846	Transcriptional regulator
AWM80_RS18590	COG2814	Major facilitator Superfamily
AWM80_RS18595	COG3420	alginic acid biosynthetic process
AWM80_RS18600	COG1953	Uracil, thiamine, allantoin
AWM80_RS18605	COG0477	Major facilitator Superfamily
AWM80_RS18610	COG1335	isochorismatase
AWM80_RS18620	COG0004	ammonium transporteR
AWM80_RS18625	COG0347	Belongs to the P(II) protein family
AWM80_RS18630	COG0671	phosphoesterase, PA-phosphatase related
AWM80_RS18640	COG0739	heme binding
AWM80_RS18645	COG1247	-acetyltransferase
AWM80_RS18665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWM80_RS18670	COG0789	Transcriptional regulator
AWM80_RS18680	COG2910	NAD(P)H-binding
AWM80_RS18685	COG1959	2 iron, 2 sulfur cluster binding
AWM80_RS18690	COG0804	urea catabolic process
AWM80_RS18695	COG0832	Belongs to the urease beta subunit family
AWM80_RS18700	COG0831	urea catabolic process
AWM80_RS18710	COG3237	CsbD-like
AWM80_RS18715	COG1994	Peptidase M50
AWM80_RS18720	COG0457	Tetratricopeptide repeat
AWM80_RS18725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AWM80_RS18730	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AWM80_RS18740	COG2304	oxidoreductase activity
AWM80_RS18750	COG2304	oxidoreductase activity
AWM80_RS18755	COG2385	sporulation resulting in formation of a cellular spore
AWM80_RS18760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWM80_RS18770	COG4836	Membrane
AWM80_RS18780	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AWM80_RS18785	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AWM80_RS18790	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AWM80_RS18795	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AWM80_RS18800	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWM80_RS18805	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWM80_RS18820	COG0356	it plays a direct role in the translocation of protons across the membrane
AWM80_RS18830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AWM80_RS18835	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AWM80_RS18840	COG4475	Protein of unknown function (DUF436)
AWM80_RS18845	COG0698	ribose 5-phosphate isomerase
AWM80_RS18850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWM80_RS18855	COG1971	Probably functions as a manganese efflux pump
AWM80_RS18860	COG0009	L-threonylcarbamoyladenylate synthase
AWM80_RS18865	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AWM80_RS18885	COG2890	protein-(glutamine-N5) methyltransferase activity
AWM80_RS18890	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AWM80_RS18895	COG0346	lactoylglutathione lyase activity
AWM80_RS18900	COG0789	Transcriptional regulator
AWM80_RS18905	COG0679	Auxin Efflux Carrier
AWM80_RS18910	COG0281	malic enzyme
AWM80_RS18915	COG1435	thymidine kinase activity
AWM80_RS18925	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AWM80_RS18935	COG1494	fructose-1,6-bisphosphatase
AWM80_RS18940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWM80_RS18945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWM80_RS18950	COG0191	fructose-bisphosphate aldolase activity
AWM80_RS18955	COG2204	response regulator
AWM80_RS18960	COG4821	SIS domain
AWM80_RS18965	COG0504	CTP synthase activity
AWM80_RS18970	COG3343	RNA polymerase activity
AWM80_RS18975	COG1960	acyl-CoA dehydrogenase activity
AWM80_RS18980	COG0247	lactate metabolic process
AWM80_RS18980	COG2181	nitrate reductase activity
AWM80_RS18985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWM80_RS18990	COG4294	response to UV
AWM80_RS19000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AWM80_RS19005	COG1132	(ABC) transporter
AWM80_RS19010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWM80_RS19020	COG2181	nitrate reductase activity
AWM80_RS19025	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AWM80_RS19030	COG1140	nitrate reductase beta subunit
AWM80_RS19035	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AWM80_RS19040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWM80_RS19050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWM80_RS19055	COG2223	nitrite transmembrane transporter activity
AWM80_RS19060	COG0018	arginyl-trna synthetase
AWM80_RS19065	COG4506	Protein conserved in bacteria
AWM80_RS19075	COG0535	radical SAM domain protein
AWM80_RS19085	COG1131	(ABC) transporter
AWM80_RS19090	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWM80_RS19095	COG0612	Peptidase, M16
AWM80_RS19100	COG0612	Peptidase, M16
AWM80_RS19110	COG3391	amine dehydrogenase activity
AWM80_RS19115	COG3391	amine dehydrogenase activity
AWM80_RS19125	COG0457	Tetratricopeptide repeat
AWM80_RS19135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AWM80_RS19140	COG0010	Belongs to the arginase family
AWM80_RS19145	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AWM80_RS19150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWM80_RS19160	COG1994	Peptidase M50
AWM80_RS19165	COG1942	4-Oxalocrotonate Tautomerase
AWM80_RS19170	COG1846	Transcriptional regulator
AWM80_RS19175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWM80_RS19185	COG0477	Major facilitator Superfamily
AWM80_RS19190	COG1959	2 iron, 2 sulfur cluster binding
AWM80_RS19195	COG3465	dGTPase activity
AWM80_RS19200	COG1078	dGTPase activity
AWM80_RS19205	COG4844	belongs to the
AWM80_RS19215	COG0697	spore germination
AWM80_RS19220	COG0095	Lipoate-protein ligase
AWM80_RS19225	COG0583	DNA-binding transcription factor activity
AWM80_RS19230	COG0280	phosphate acetyltransferase
AWM80_RS19235	COG3253	May function as heme-dependent peroxidase
AWM80_RS19240	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS19245	COG0436	Aminotransferase
AWM80_RS19250	COG2814	Major facilitator Superfamily
AWM80_RS19255	COG0151	Belongs to the GarS family
AWM80_RS19260	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS19265	COG1917	Cupin 2, conserved barrel domain protein
AWM80_RS19270	COG0077	Prephenate dehydratase
AWM80_RS19275	COG2814	Major facilitator Superfamily
AWM80_RS19280	COG0833	amino acid
AWM80_RS19285	COG4187	Peptidase family M20/M25/M40
AWM80_RS19290	COG1012	belongs to the aldehyde dehydrogenase family
AWM80_RS19295	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWM80_RS19305	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AWM80_RS19310	COG1091	dTDP-4-dehydrorhamnose reductase activity
AWM80_RS19315	COG1088	dTDP-glucose 4,6-dehydratase activity
AWM80_RS19320	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AWM80_RS19325	COG3980	spore coat polysaccharide biosynthesis protein
AWM80_RS19330	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AWM80_RS19335	COG2089	acid synthase
AWM80_RS19340	COG0456	acetyltransferase
AWM80_RS19345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AWM80_RS19350	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWM80_RS19355	COG0463	Glycosyl transferase, family 2
AWM80_RS19370	COG2363	Small membrane protein
AWM80_RS19375	COG2233	PERMEase
AWM80_RS19385	COG1012	belongs to the aldehyde dehydrogenase family
AWM80_RS19390	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AWM80_RS19395	COG1216	Glycosyl transferase, family 2
AWM80_RS19410	COG1695	Transcriptional regulator
AWM80_RS19415	COG0351	phosphomethylpyrimidine kinase
AWM80_RS19425	COG1621	beta-fructofuranosidase activity
AWM80_RS19430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWM80_RS19430	COG1263	PTS System
AWM80_RS19435	COG2116	formate transmembrane transporter activity
AWM80_RS19440	COG3711	transcriptional antiterminator
AWM80_RS19450	COG1404	Belongs to the peptidase S8 family
AWM80_RS19455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWM80_RS19460	COG0778	Nitroreductase
AWM80_RS19465	COG0772	Belongs to the SEDS family
AWM80_RS19475	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AWM80_RS19480	COG1845	cytochrome c oxidase, subunit III
AWM80_RS19485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWM80_RS19490	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWM80_RS19495	COG2261	transglycosylase associated protein
AWM80_RS19500	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AWM80_RS19505	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AWM80_RS19510	COG2246	polysaccharide biosynthetic process
AWM80_RS19515	COG1309	transcriptional regulator
AWM80_RS19525	COG3162	membrane
AWM80_RS19535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AWM80_RS19540	COG2837	iron assimilation
AWM80_RS19545	COG2822	iron ion transport
AWM80_RS19550	COG0672	)-iron permease
AWM80_RS19555	COG0352	thiamine-phosphate diphosphorylase activity
AWM80_RS19560	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AWM80_RS19565	COG0583	DNA-binding transcription factor activity
AWM80_RS19570	COG1380	Effector of murein hydrolase LrgA
AWM80_RS19575	COG1346	cytolysis
AWM80_RS19580	COG2814	Major facilitator Superfamily
AWM80_RS19585	COG4895	conserved protein (DUF2196)
AWM80_RS19590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AWM80_RS19595	COG0346	lactoylglutathione lyase activity
AWM80_RS19605	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWM80_RS19610	COG1404	Belongs to the peptidase S8 family
AWM80_RS19615	COG1263	PTS System
AWM80_RS19615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWM80_RS19620	COG3711	transcriptional antiterminator
AWM80_RS19625	COG1442	glycosyl transferase family 8
AWM80_RS19630	COG5522	Integral membrane protein (intg_mem_TP0381)
AWM80_RS19635	COG1846	Transcriptional regulator
AWM80_RS19640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWM80_RS19645	COG2234	aminopeptidase activity
AWM80_RS19650	COG2357	RelA SpoT domain protein
AWM80_RS19655	COG1575	Belongs to the MenA family. Type 1 subfamily
AWM80_RS19670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWM80_RS19675	COG1696	Membrane protein involved in D-alanine export
AWM80_RS19680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWM80_RS19685	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AWM80_RS19690	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AWM80_RS19695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWM80_RS19700	COG1486	melibiose metabolic process
AWM80_RS19705	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWM80_RS19710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWM80_RS19715	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWM80_RS19720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWM80_RS19720	COG3711	transcriptional antiterminator
AWM80_RS19730	COG2094	Belongs to the DNA glycosylase MPG family
AWM80_RS19735	COG0753	catalase activity
AWM80_RS19740	COG2814	Major facilitator Superfamily
AWM80_RS19745	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AWM80_RS19750	COG1131	(ABC) transporter
AWM80_RS19770	COG1595	DNA-templated transcription, initiation
AWM80_RS19775	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AWM80_RS19780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AWM80_RS19785	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AWM80_RS19790	COG4988	ABC transporter
AWM80_RS19795	COG1294	oxidase, subunit
AWM80_RS19800	COG1271	oxidase subunit
AWM80_RS19805	COG3493	citrate carrier protein
AWM80_RS19810	COG0501	Belongs to the peptidase M48B family
AWM80_RS19820	COG0726	polysaccharide deacetylase
AWM80_RS19825	COG3842	ATPase activity
AWM80_RS19830	COG2508	Transcriptional regulator
AWM80_RS19835	COG1012	belongs to the aldehyde dehydrogenase family
AWM80_RS19840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWM80_RS19850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AWM80_RS19855	COG1881	PFAM PEBP family protein
AWM80_RS19860	COG0583	DNA-binding transcription factor activity
AWM80_RS19870	COG4585	Histidine kinase
AWM80_RS19875	COG2197	response regulator
AWM80_RS19880	COG2195	Cleaves the N-terminal amino acid of tripeptides
AWM80_RS19895	COG4894	glucomannan catabolic process
AWM80_RS19900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWM80_RS19905	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWM80_RS19910	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS19915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AWM80_RS19920	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AWM80_RS19925	COG2610	gluconate transmembrane transporter activity
AWM80_RS19935	COG0500	methyltransferase
AWM80_RS19940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWM80_RS19960	COG0693	protein deglycase activity
AWM80_RS19960	COG0753	catalase activity
AWM80_RS19965	COG2851	Citrate transporter
AWM80_RS19970	COG2273	Hydrolase Family 16
AWM80_RS19975	COG3711	transcriptional antiterminator
AWM80_RS19985	COG2270	Major facilitator Superfamily
AWM80_RS19990	COG0513	Belongs to the DEAD box helicase family
AWM80_RS19995	COG2755	lipolytic protein G-D-S-L family
AWM80_RS19995	COG3401	FG-GAP repeat protein
AWM80_RS20050	COG3209	COG3209 Rhs family protein
AWM80_RS20055	COG0697	spore germination
AWM80_RS20060	COG0589	response to stress
AWM80_RS20065	COG2723	6-phospho-beta-galactosidase activity
AWM80_RS20070	COG2190	(PTS) system
AWM80_RS20070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWM80_RS20070	COG1263	PTS System
AWM80_RS20085	COG5444	nuclease activity
AWM80_RS20100	COG3507	Belongs to the glycosyl hydrolase 43 family
AWM80_RS20115	COG2986	histidine ammonia-lyase
AWM80_RS20120	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AWM80_RS20125	COG1228	amidohydrolase
AWM80_RS20130	COG0010	Belongs to the arginase family
AWM80_RS20135	COG0833	amino acid
AWM80_RS20140	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AWM80_RS20145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWM80_RS20150	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AWM80_RS20155	COG2390	Transcriptional regulator
AWM80_RS20165	COG3192	ethanolamine utilization protein
AWM80_RS20170	COG2079	MmgE PrpD family protein
AWM80_RS20175	COG1473	amidohydrolase
AWM80_RS20180	COG1126	abc transporter atp-binding protein
AWM80_RS20185	COG0765	amino acid transport
AWM80_RS20190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWM80_RS20195	COG0456	acetyltransferase
AWM80_RS20200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWM80_RS20210	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AWM80_RS20215	COG0561	phosphatase activity
AWM80_RS20245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWM80_RS20250	COG5294	Protein conserved in bacteria
AWM80_RS20255	COG0577	efflux transmembrane transporter activity
AWM80_RS20260	COG1136	(ABC) transporter
AWM80_RS20265	COG2205	protein histidine kinase activity
AWM80_RS20270	COG0745	RESPONSE REGULATOR receiver
AWM80_RS20275	COG0191	fructose-bisphosphate aldolase activity
AWM80_RS20280	COG1082	Xylose isomerase domain protein TIM barrel
AWM80_RS20285	COG1082	Xylose isomerase domain protein TIM barrel
AWM80_RS20290	COG0673	inositol 2-dehydrogenase activity
AWM80_RS20295	COG2814	Major facilitator Superfamily
AWM80_RS20300	COG1082	Xylose isomerase domain protein TIM barrel
AWM80_RS20305	COG3962	Belongs to the TPP enzyme family
AWM80_RS20310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWM80_RS20315	COG3718	enzyme involved in inositol metabolism
AWM80_RS20320	COG1012	belongs to the aldehyde dehydrogenase family
AWM80_RS20325	COG1349	DNA-binding transcription factor activity
AWM80_RS20330	COG0667	Aldo Keto reductase
AWM80_RS20345	COG2814	Major facilitator Superfamily
AWM80_RS20350	COG0326	Molecular chaperone. Has ATPase activity
AWM80_RS20360	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS20365	COG1309	transcriptional regulator
AWM80_RS20370	COG1012	belongs to the aldehyde dehydrogenase family
AWM80_RS20375	COG0456	acetyltransferase
AWM80_RS20380	COG2850	peptidyl-arginine hydroxylation
AWM80_RS20385	COG2226	methyltransferase
AWM80_RS20400	COG0367	asparagine synthase
AWM80_RS20405	COG2814	Major facilitator Superfamily
AWM80_RS20410	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AWM80_RS20420	COG1714	RDD family
AWM80_RS20425	COG2311	Membrane
AWM80_RS20430	COG1917	Cupin 2, conserved barrel domain protein
AWM80_RS20435	COG1309	transcriptional regulator
AWM80_RS20440	COG1028	Short-chain dehydrogenase reductase Sdr
AWM80_RS20445	COG1846	Transcriptional regulator
AWM80_RS20450	COG1380	Effector of murein hydrolase LrgA
AWM80_RS20455	COG1346	cytolysis
AWM80_RS20460	COG5039	Polysaccharide pyruvyl transferase
AWM80_RS20465	COG1929	Belongs to the glycerate kinase type-1 family
AWM80_RS20470	COG1802	Transcriptional regulator
AWM80_RS20475	COG1070	Carbohydrate kinase
AWM80_RS20480	COG2610	gluconate transmembrane transporter activity
AWM80_RS20485	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AWM80_RS20490	COG0450	alkyl hydroperoxide reductase
AWM80_RS20495	COG3634	alkyl hydroperoxide reductase activity
AWM80_RS20500	COG2723	6-phospho-beta-galactosidase activity
AWM80_RS20505	COG2190	(PTS) system
AWM80_RS20510	COG2188	Transcriptional regulator
AWM80_RS20525	COG1131	(ABC) transporter
AWM80_RS20530	COG1994	Peptidase M50
AWM80_RS20535	COG0535	radical SAM domain protein
AWM80_RS20545	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AWM80_RS20560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AWM80_RS20565	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AWM80_RS20575	COG1063	alcohol dehydrogenase
AWM80_RS20595	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AWM80_RS20600	COG0456	acetyltransferase
AWM80_RS20605	COG0457	Tetratricopeptide repeat
AWM80_RS20615	COG0010	Belongs to the arginase family
AWM80_RS20620	COG0833	amino acid
AWM80_RS20625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWM80_RS20630	COG3829	transcription factor binding
AWM80_RS20635	COG5002	protein histidine kinase activity
AWM80_RS20645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWM80_RS20650	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AWM80_RS20655	COG4853	Protein conserved in bacteria
AWM80_RS20660	COG4863	YycH protein
AWM80_RS20665	COG5002	protein histidine kinase activity
AWM80_RS20670	COG0745	RESPONSE REGULATOR receiver
AWM80_RS20700	COG0346	lactoylglutathione lyase activity
AWM80_RS20705	COG0305	Participates in initiation and elongation during chromosome replication
AWM80_RS20725	COG3093	addiction module antidote protein HigA
AWM80_RS20730	COG2807	transmembrane transport
AWM80_RS20735	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWM80_RS20740	COG0359	binds to the 23S rRNA
AWM80_RS20745	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AWM80_RS20750	COG4241	membrane
AWM80_RS20760	COG5577	PFAM Coat F domain
AWM80_RS20765	COG1733	regulation of RNA biosynthetic process
AWM80_RS20770	COG1227	inorganic diphosphatase activity
AWM80_RS20785	COG2271	Major facilitator Superfamily
AWM80_RS20795	COG4319	ketosteroid isomerase
AWM80_RS20825	COG1131	(ABC) transporter
AWM80_RS20835	COG4319	ketosteroid isomerase
AWM80_RS20840	COG1357	PFAM Pentapeptide repeats (8 copies)
AWM80_RS20845	COG2814	Major facilitator Superfamily
AWM80_RS20850	COG0583	DNA-binding transcription factor activity
AWM80_RS20855	COG2153	protein acetylation
AWM80_RS20865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWM80_RS20870	COG1846	Transcriptional regulator
AWM80_RS20875	COG2153	protein acetylation
AWM80_RS20880	COG2364	Membrane
AWM80_RS20885	COG0456	acetyltransferase
AWM80_RS20890	COG2315	Protein conserved in bacteria
AWM80_RS20895	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AWM80_RS20900	COG2814	Major facilitator Superfamily
AWM80_RS20905	COG1331	Highly conserved protein containing a thioredoxin domain
AWM80_RS20910	COG0789	Transcriptional regulator
AWM80_RS20915	COG0697	spore germination
AWM80_RS20920	COG1331	Highly conserved protein containing a thioredoxin domain
AWM80_RS20925	COG1266	CAAX protease self-immunity
AWM80_RS20930	COG2814	Major facilitator Superfamily
AWM80_RS20930	COG0477	Major facilitator Superfamily
AWM80_RS20935	COG0110	maltose O-acetyltransferase activity
AWM80_RS20940	COG0346	lactoylglutathione lyase activity
AWM80_RS20945	COG1609	Transcriptional regulator
AWM80_RS20950	COG0708	Exodeoxyribonuclease III
AWM80_RS20955	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AWM80_RS20960	COG0629	single-stranded DNA binding
AWM80_RS20965	COG0360	Binds together with S18 to 16S ribosomal RNA
AWM80_RS20970	COG0012	GTP binding
AWM80_RS20975	COG0243	molybdopterin cofactor binding
AWM80_RS20980	COG4481	Protein conserved in bacteria
AWM80_RS20985	COG3949	Membrane
AWM80_RS20995	COG1475	DNA binding
AWM80_RS21000	COG1192	Involved in chromosome partitioning
AWM80_RS21010	COG1475	DNA binding
AWM80_RS21015	COG0357	Ribosomal RNA small subunit methyltransferase G
AWM80_RS21020	COG0445	tRNA wobble uridine modification
AWM80_RS21025	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWM80_RS21030	COG1847	R3H domain protein
AWM80_RS21035	COG0706	membrane insertase activity
AWM80_RS21040	COG0594	ribonuclease P activity