locus-tag	class	description
AS891_RS00010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_RS00020	COG1733	regulation of RNA biosynthetic process
AS891_RS00025	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AS891_RS00030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AS891_RS00035	COG3290	protein histidine kinase activity
AS891_RS00035	COG0840	transmembrane signaling receptor activity
AS891_RS00040	COG3209	COG3209 Rhs family protein
AS891_RS00050	COG2723	6-phospho-beta-galactosidase activity
AS891_RS00060	COG1714	RDD family
AS891_RS00070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_RS00075	COG0765	amino acid transport
AS891_RS00080	COG0523	cobalamin synthesis protein
AS891_RS00090	COG1376	ErfK ybiS ycfS ynhG family protein
AS891_RS00095	COG1469	GTP cyclohydrolase I activity
AS891_RS00100	COG2223	nitrite transmembrane transporter activity
AS891_RS00105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS891_RS00110	COG0243	molybdopterin cofactor binding
AS891_RS00115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS891_RS00120	COG2146	nitrite reductase [NAD(P)H] activity
AS891_RS00125	COG1587	Uroporphyrinogen-III synthase
AS891_RS00125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS891_RS00130	COG0492	ferredoxin-NADP+ reductase activity
AS891_RS00135	COG2267	carboxylic ester hydrolase activity
AS891_RS00140	COG0701	Predicted permease
AS891_RS00145	COG3689	TIGRFAM TIGR03943 family protein
AS891_RS00150	COG2508	Transcriptional regulator
AS891_RS00155	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS891_RS00160	COG1012	belongs to the aldehyde dehydrogenase family
AS891_RS00165	COG0506	proline dehydrogenase activity
AS891_RS00170	COG3541	Predicted nucleotidyltransferase
AS891_RS00175	COG3458	cephalosporin-C deacetylase activity
AS891_RS00180	COG0583	DNA-binding transcription factor activity
AS891_RS00185	COG2226	methyltransferase
AS891_RS00190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AS891_RS00195	COG1660	Displays ATPase and GTPase activities
AS891_RS00200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AS891_RS00205	COG3665	Urea carboxylase-associated protein
AS891_RS00210	COG1113	amino acid transport
AS891_RS00215	COG3403	YqcI/YcgG family
AS891_RS00220	COG1280	lysine exporter protein (LysE YggA)
AS891_RS00225	COG1846	Transcriptional regulator
AS891_RS00230	COG2814	Major facilitator Superfamily
AS891_RS00235	COG1620	l-lactate permease
AS891_RS00240	COG0039	L-malate dehydrogenase activity
AS891_RS00245	COG0366	Alpha amylase catalytic
AS891_RS00260	COG1288	antiporter activity
AS891_RS00265	COG1473	amidohydrolase
AS891_RS00270	COG2113	Glycine betaine
AS891_RS00275	COG4176	ABC-type proline glycine betaine transport system permease component
AS891_RS00280	COG0517	IMP dehydrogenase activity
AS891_RS00280	COG4175	Glycine betaine
AS891_RS00285	COG0640	Transcriptional regulator
AS891_RS00290	COG2814	Major facilitator Superfamily
AS891_RS00295	COG0477	Major facilitator Superfamily
AS891_RS00300	COG3853	Toxic anion resistance protein (TelA)
AS891_RS00310	COG0861	Integral membrane protein TerC family
AS891_RS00315	COG2310	stress, protein
AS891_RS00320	COG2310	stress, protein
AS891_RS00325	COG2310	stress, protein
AS891_RS00330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_RS00335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS891_RS00340	COG1121	(ABC) transporter
AS891_RS00345	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS891_RS00350	COG0366	Alpha amylase catalytic
AS891_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS00360	COG0457	Tetratricopeptide repeat
AS891_RS00365	COG1876	peptidase activity
AS891_RS00370	COG1595	DNA-templated transcription, initiation
AS891_RS00375	COG1595	DNA-templated transcription, initiation
AS891_RS00385	COG0667	Aldo Keto reductase
AS891_RS00390	COG1668	transmembrane transport
AS891_RS00395	COG4555	ABC transporter
AS891_RS00400	COG3279	Response regulator of the LytR AlgR family
AS891_RS00405	COG3290	protein histidine kinase activity
AS891_RS00410	COG1405	negative regulation of cell septum assembly
AS891_RS00410	COG3012	SEC-C Motif Domain Protein
AS891_RS00415	COG1714	RDD family
AS891_RS00420	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AS891_RS00425	COG0252	asparaginase activity
AS891_RS00430	COG1309	transcriptional regulator
AS891_RS00435	COG0477	Major facilitator Superfamily
AS891_RS00440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS891_RS00445	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AS891_RS00450	COG0805	protein transport
AS891_RS00455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS891_RS00460	COG3540	Alkaline phosphatase
AS891_RS00470	COG2304	oxidoreductase activity
AS891_RS00475	COG3773	Cell wall hydrolase
AS891_RS00495	COG1131	(ABC) transporter
AS891_RS00500	COG2205	protein histidine kinase activity
AS891_RS00505	COG0745	RESPONSE REGULATOR receiver
AS891_RS00510	COG0697	spore germination
AS891_RS00520	COG3173	Aminoglycoside phosphotransferase
AS891_RS00525	COG2721	sulfolactate sulfo-lyase activity
AS891_RS00530	COG2186	Transcriptional regulator
AS891_RS00535	COG4948	Mandelate Racemase Muconate Lactonizing
AS891_RS00540	COG2271	Major facilitator Superfamily
AS891_RS00545	COG1012	belongs to the aldehyde dehydrogenase family
AS891_RS00550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS891_RS00555	COG0784	Response regulator, receiver
AS891_RS00560	COG4191	Histidine kinase
AS891_RS00565	COG2066	Belongs to the glutaminase family
AS891_RS00570	COG1115	amino acid carrier protein
AS891_RS00580	COG2040	homocysteine
AS891_RS00585	COG0833	amino acid
AS891_RS00590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS891_RS00600	COG2188	Transcriptional regulator
AS891_RS00605	COG0363	glucosamine-6-phosphate deaminase activity
AS891_RS00610	COG1263	PTS System
AS891_RS00610	COG2190	(PTS) system
AS891_RS00610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_RS00615	COG1301	dicarboxylic acid transport
AS891_RS00620	COG1054	Belongs to the UPF0176 family
AS891_RS00625	COG2207	Transcriptional regulator
AS891_RS00630	COG2312	Erythromycin esterase
AS891_RS00640	COG0688	phosphatidylethanolamine metabolic process
AS891_RS00645	COG0586	Pfam SNARE associated Golgi protein
AS891_RS00650	COG1183	phosphatidylcholine synthase activity
AS891_RS00655	COG0596	Alpha beta hydrolase
AS891_RS00665	COG3591	Belongs to the peptidase S1B family
AS891_RS00670	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AS891_RS00675	COG1917	Cupin 2, conserved barrel domain protein
AS891_RS00675	COG2207	Transcriptional regulator
AS891_RS00680	COG0697	spore germination
AS891_RS00685	COG3409	Peptidoglycan-binding domain 1 protein
AS891_RS00700	COG2271	Major facilitator Superfamily
AS891_RS00705	COG0456	acetyltransferase
AS891_RS00705	COG1846	Transcriptional regulator
AS891_RS00715	COG2271	Major facilitator Superfamily
AS891_RS00720	COG0584	glycerophosphoryl diester phosphodiesterase
AS891_RS00725	COG0531	amino acid
AS891_RS00735	COG2124	cytochrome p450
AS891_RS00740	COG2602	Beta-lactamase
AS891_RS00755	COG1113	amino acid transport
AS891_RS00770	COG0515	serine threonine protein kinase
AS891_RS00780	COG0642	Histidine kinase
AS891_RS00785	COG0745	RESPONSE REGULATOR receiver
AS891_RS00790	COG0596	Alpha beta hydrolase
AS891_RS00795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_RS00800	COG1413	lyase activity
AS891_RS00810	COG1131	(ABC) transporter
AS891_RS00815	COG1266	CAAX protease self-immunity
AS891_RS00820	COG0535	radical SAM domain protein
AS891_RS00830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AS891_RS00835	COG2814	Major facilitator Superfamily
AS891_RS00840	COG0640	Transcriptional regulator
AS891_RS00850	COG5609	conserved protein (DUF2294)
AS891_RS00860	COG0288	reversible hydration of carbon dioxide
AS891_RS00865	COG3002	Belongs to the UPF0753 family
AS891_RS00870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS891_RS00875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS891_RS00880	COG2169	Transcriptional regulator
AS891_RS00885	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AS891_RS00890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AS891_RS00895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS891_RS00900	COG4856	YbbR-like protein
AS891_RS00905	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AS891_RS00910	COG5662	AntiSigma factor
AS891_RS00915	COG1595	DNA-templated transcription, initiation
AS891_RS00945	COG1683	Conserved Protein
AS891_RS00950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_RS00955	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AS891_RS00960	COG1737	Transcriptional regulator
AS891_RS00965	COG1263	PTS System
AS891_RS00965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_RS00970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS891_RS00975	COG1472	Belongs to the glycosyl hydrolase 3 family
AS891_RS00980	COG3876	Protein conserved in bacteria
AS891_RS00985	COG2207	Transcriptional regulator
AS891_RS00985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS891_RS00990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS891_RS00995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_RS01000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_RS01005	COG2819	hydrolase of the alpha beta superfamily
AS891_RS01010	COG0385	Bile acid
AS891_RS01015	COG0659	secondary active sulfate transmembrane transporter activity
AS891_RS01100	COG0726	polysaccharide deacetylase
AS891_RS01105	COG2194	sulfuric ester hydrolase activity
AS891_RS01115	COG0489	protein tyrosine kinase activity
AS891_RS01120	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS891_RS01130	COG2226	methyltransferase
AS891_RS01135	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AS891_RS01140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AS891_RS01145	COG0101	tRNA pseudouridine synthase activity
AS891_RS01150	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AS891_RS01155	COG1122	ATPase activity
AS891_RS01160	COG1122	ATPase activity
AS891_RS01165	COG0203	ribosomal protein L17
AS891_RS01170	COG0202	RNA polymerase activity
AS891_RS01175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AS891_RS01180	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AS891_RS01185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AS891_RS01195	COG2163	COG2163 Ribosomal protein L14E L6E L27E
AS891_RS01200	COG0024	Methionine aminopeptidase
AS891_RS01205	COG0563	adenylate kinase activity
AS891_RS01210	COG0201	protein transport
AS891_RS01215	COG0200	Binds to the 23S rRNA
AS891_RS01225	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AS891_RS01230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AS891_RS01235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AS891_RS01240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AS891_RS01250	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AS891_RS01260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AS891_RS01265	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AS891_RS01275	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AS891_RS01280	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AS891_RS01295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AS891_RS01305	COG0088	Forms part of the polypeptide exit tunnel
AS891_RS01310	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AS891_RS01320	COG0596	Alpha beta hydrolase
AS891_RS01325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AS891_RS01330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AS891_RS01335	COG0049	tRNA binding
AS891_RS01340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AS891_RS01345	COG1358	cellular component organization or biogenesis
AS891_RS01350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AS891_RS01355	COG0085	RNA polymerase activity
AS891_RS01360	COG2813	Specifically methylates the guanine in position
AS891_RS01370	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AS891_RS01375	COG0081	regulation of translation
AS891_RS01385	COG0250	Participates in transcription elongation, termination and antitermination
AS891_RS01390	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS891_RS01400	COG1595	DNA-templated transcription, initiation
AS891_RS01405	COG3688	RNA-binding protein containing a PIN domain
AS891_RS01410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS891_RS01415	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AS891_RS01420	COG0215	cysteine-tRNA ligase activity
AS891_RS01425	COG1045	serine acetyltransferase
AS891_RS01435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AS891_RS01440	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AS891_RS01445	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AS891_RS01450	COG4956	integral membrane protein (PIN domain superfamily)
AS891_RS01455	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AS891_RS01460	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AS891_RS01465	COG0542	response to heat
AS891_RS01470	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AS891_RS01475	COG3880	PFAM UvrB UvrC protein
AS891_RS01480	COG4463	regulation of RNA biosynthetic process
AS891_RS01565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AS891_RS01570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AS891_RS01575	COG1396	sequence-specific DNA binding
AS891_RS01580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS891_RS01585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AS891_RS01590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AS891_RS01595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS891_RS01600	COG0512	Glutamine amidotransferase of anthranilate synthase
AS891_RS01605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS891_RS01610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS891_RS01615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AS891_RS01620	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AS891_RS01625	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AS891_RS01630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS891_RS01635	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AS891_RS01640	COG0037	tRNA processing
AS891_RS01645	COG0515	serine threonine protein kinase
AS891_RS01650	COG2304	oxidoreductase activity
AS891_RS01655	COG2208	phosphoserine phosphatase activity
AS891_RS01670	COG1098	S1 RNA binding domain
AS891_RS01675	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AS891_RS01690	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AS891_RS01695	COG3956	TIGRFAM MazG family protein
AS891_RS01700	COG2244	polysaccharide biosynthetic process
AS891_RS01705	COG2002	toxin-antitoxin pair type II binding
AS891_RS01710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AS891_RS01720	COG0193	aminoacyl-tRNA hydrolase activity
AS891_RS01725	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AS891_RS01730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AS891_RS01735	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AS891_RS01745	COG2088	sporulation resulting in formation of a cellular spore
AS891_RS01750	COG0251	oxidation-reduction process
AS891_RS01755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS891_RS01760	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AS891_RS01770	COG4466	Protein conserved in bacteria
AS891_RS01780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AS891_RS01785	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AS891_RS01790	COG3583	domain protein
AS891_RS01790	COG3584	3D domain protein
AS891_RS01795	COG0084	hydrolase, TatD family'
AS891_RS01800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS891_RS01800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS891_RS01805	COG2002	toxin-antitoxin pair type II binding
AS891_RS01810	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AS891_RS01815	COG2827	Endonuclease containing a URI domain
AS891_RS01820	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AS891_RS01825	COG4467	Involved in initiation control of chromosome replication
AS891_RS01830	COG1774	PSP1 C-terminal conserved region
AS891_RS01835	COG0470	DNA polymerase III
AS891_RS01840	COG1728	Protein conserved in bacteria
AS891_RS01845	COG3870	Protein conserved in bacteria
AS891_RS01850	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AS891_RS01855	COG1982	Orn Lys Arg decarboxylase major
AS891_RS01860	COG3853	Toxic anion resistance protein (TelA)
AS891_RS01865	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AS891_RS01910	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AS891_RS01915	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AS891_RS01920	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AS891_RS01930	COG0590	tRNA wobble adenosine to inosine editing
AS891_RS01935	COG1335	isochorismatase
AS891_RS01940	COG1388	LysM domain
AS891_RS01940	COG3858	chitin binding
AS891_RS01945	COG1428	Deoxynucleoside kinase
AS891_RS01950	COG1428	Deoxynucleoside kinase
AS891_RS01960	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AS891_RS01965	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AS891_RS01970	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AS891_RS01975	COG1686	Belongs to the peptidase S11 family
AS891_RS01980	COG0516	GMP reductase activity
AS891_RS01980	COG0517	IMP dehydrogenase activity
AS891_RS02015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS891_RS02020	COG0187	DNA topoisomerase II activity
AS891_RS02030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AS891_RS02035	COG2501	S4 domain
AS891_RS02040	COG0592	DNA-directed DNA polymerase activity
AS891_RS02045	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AS891_RS02055	COG0594	ribonuclease P activity
AS891_RS02060	COG0706	membrane insertase activity
AS891_RS02065	COG1847	R3H domain protein
AS891_RS02070	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AS891_RS02075	COG0445	tRNA wobble uridine modification
AS891_RS02080	COG0357	Ribosomal RNA small subunit methyltransferase G
AS891_RS02085	COG1475	DNA binding
AS891_RS02095	COG1192	Involved in chromosome partitioning
AS891_RS02100	COG1475	DNA binding
AS891_RS02110	COG3949	Membrane
AS891_RS02115	COG4481	Protein conserved in bacteria
AS891_RS02120	COG0243	molybdopterin cofactor binding
AS891_RS02125	COG0012	GTP binding
AS891_RS02130	COG0360	Binds together with S18 to 16S ribosomal RNA
AS891_RS02135	COG0629	single-stranded DNA binding
AS891_RS02140	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AS891_RS02145	COG0708	Exodeoxyribonuclease III
AS891_RS02150	COG1609	Transcriptional regulator
AS891_RS02155	COG0346	lactoylglutathione lyase activity
AS891_RS02160	COG0110	maltose O-acetyltransferase activity
AS891_RS02165	COG2814	Major facilitator Superfamily
AS891_RS02165	COG0477	Major facilitator Superfamily
AS891_RS02170	COG1266	CAAX protease self-immunity
AS891_RS02175	COG1331	Highly conserved protein containing a thioredoxin domain
AS891_RS02180	COG0697	spore germination
AS891_RS02185	COG0789	Transcriptional regulator
AS891_RS02190	COG1331	Highly conserved protein containing a thioredoxin domain
AS891_RS02195	COG2814	Major facilitator Superfamily
AS891_RS02200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS891_RS02205	COG2315	Protein conserved in bacteria
AS891_RS02210	COG0456	acetyltransferase
AS891_RS02215	COG2364	Membrane
AS891_RS02220	COG2153	protein acetylation
AS891_RS02225	COG1846	Transcriptional regulator
AS891_RS02230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_RS02240	COG2153	protein acetylation
AS891_RS02245	COG0583	DNA-binding transcription factor activity
AS891_RS02250	COG2814	Major facilitator Superfamily
AS891_RS02255	COG1357	PFAM Pentapeptide repeats (8 copies)
AS891_RS02260	COG4319	ketosteroid isomerase
AS891_RS02270	COG1131	(ABC) transporter
AS891_RS02300	COG4319	ketosteroid isomerase
AS891_RS02310	COG2271	Major facilitator Superfamily
AS891_RS02325	COG1227	inorganic diphosphatase activity
AS891_RS02330	COG1733	regulation of RNA biosynthetic process
AS891_RS02335	COG5577	PFAM Coat F domain
AS891_RS02345	COG4241	membrane
AS891_RS02350	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AS891_RS02355	COG0359	binds to the 23S rRNA
AS891_RS02360	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AS891_RS02365	COG2807	transmembrane transport
AS891_RS02370	COG3093	addiction module antidote protein HigA
AS891_RS02390	COG0305	Participates in initiation and elongation during chromosome replication
AS891_RS02395	COG0346	lactoylglutathione lyase activity
AS891_RS02425	COG0745	RESPONSE REGULATOR receiver
AS891_RS02430	COG5002	protein histidine kinase activity
AS891_RS02435	COG4863	YycH protein
AS891_RS02440	COG4853	Protein conserved in bacteria
AS891_RS02445	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AS891_RS02450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS891_RS02460	COG5002	protein histidine kinase activity
AS891_RS02465	COG3829	transcription factor binding
AS891_RS02470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS891_RS02475	COG0833	amino acid
AS891_RS02480	COG0010	Belongs to the arginase family
AS891_RS02490	COG0457	Tetratricopeptide repeat
AS891_RS02495	COG0456	acetyltransferase
AS891_RS02500	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AS891_RS02520	COG1063	alcohol dehydrogenase
AS891_RS02535	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AS891_RS02540	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS891_RS02550	COG5293	efflux transmembrane transporter activity
AS891_RS02555	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AS891_RS02565	COG0535	radical SAM domain protein
AS891_RS02570	COG1994	Peptidase M50
AS891_RS02575	COG1131	(ABC) transporter
AS891_RS02590	COG2188	Transcriptional regulator
AS891_RS02595	COG2190	(PTS) system
AS891_RS02600	COG2723	6-phospho-beta-galactosidase activity
AS891_RS02605	COG3634	alkyl hydroperoxide reductase activity
AS891_RS02610	COG0450	alkyl hydroperoxide reductase
AS891_RS02615	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AS891_RS02620	COG2610	gluconate transmembrane transporter activity
AS891_RS02625	COG1070	Carbohydrate kinase
AS891_RS02630	COG1802	Transcriptional regulator
AS891_RS02635	COG1929	Belongs to the glycerate kinase type-1 family
AS891_RS02640	COG5039	Polysaccharide pyruvyl transferase
AS891_RS02645	COG1346	cytolysis
AS891_RS02650	COG1380	Effector of murein hydrolase LrgA
AS891_RS02655	COG1846	Transcriptional regulator
AS891_RS02660	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS02665	COG1309	transcriptional regulator
AS891_RS02670	COG1917	Cupin 2, conserved barrel domain protein
AS891_RS02675	COG2311	Membrane
AS891_RS02680	COG1714	RDD family
AS891_RS02690	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS891_RS02695	COG2814	Major facilitator Superfamily
AS891_RS02700	COG0367	asparagine synthase
AS891_RS02715	COG2226	methyltransferase
AS891_RS02720	COG2850	peptidyl-arginine hydroxylation
AS891_RS02725	COG0456	acetyltransferase
AS891_RS02730	COG1012	belongs to the aldehyde dehydrogenase family
AS891_RS02735	COG1309	transcriptional regulator
AS891_RS02740	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS02750	COG0326	Molecular chaperone. Has ATPase activity
AS891_RS02755	COG2814	Major facilitator Superfamily
AS891_RS02770	COG0667	Aldo Keto reductase
AS891_RS02775	COG1349	DNA-binding transcription factor activity
AS891_RS02780	COG1012	belongs to the aldehyde dehydrogenase family
AS891_RS02785	COG3718	enzyme involved in inositol metabolism
AS891_RS02790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS891_RS02795	COG3962	Belongs to the TPP enzyme family
AS891_RS02800	COG1082	Xylose isomerase domain protein TIM barrel
AS891_RS02805	COG2814	Major facilitator Superfamily
AS891_RS02810	COG0673	inositol 2-dehydrogenase activity
AS891_RS02815	COG1082	Xylose isomerase domain protein TIM barrel
AS891_RS02820	COG1082	Xylose isomerase domain protein TIM barrel
AS891_RS02825	COG0191	fructose-bisphosphate aldolase activity
AS891_RS02830	COG0745	RESPONSE REGULATOR receiver
AS891_RS02835	COG2205	protein histidine kinase activity
AS891_RS02840	COG1136	(ABC) transporter
AS891_RS02845	COG0577	efflux transmembrane transporter activity
AS891_RS02850	COG5294	Protein conserved in bacteria
AS891_RS02855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS891_RS02885	COG0561	phosphatase activity
AS891_RS02890	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AS891_RS02900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_RS02905	COG0456	acetyltransferase
AS891_RS02910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_RS02915	COG0765	amino acid transport
AS891_RS02920	COG1126	abc transporter atp-binding protein
AS891_RS02925	COG1473	amidohydrolase
AS891_RS02930	COG2079	MmgE PrpD family protein
AS891_RS02935	COG3192	ethanolamine utilization protein
AS891_RS02945	COG2390	Transcriptional regulator
AS891_RS02950	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AS891_RS02955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS891_RS02960	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AS891_RS02965	COG0833	amino acid
AS891_RS02970	COG0010	Belongs to the arginase family
AS891_RS02975	COG1228	amidohydrolase
AS891_RS02980	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AS891_RS02985	COG2986	histidine ammonia-lyase
AS891_RS03000	COG3507	Belongs to the glycosyl hydrolase 43 family
AS891_RS03015	COG5444	nuclease activity
AS891_RS03030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_RS03030	COG1263	PTS System
AS891_RS03030	COG2190	(PTS) system
AS891_RS03035	COG2723	6-phospho-beta-galactosidase activity
AS891_RS03040	COG0589	response to stress
AS891_RS03045	COG0697	spore germination
AS891_RS03050	COG3209	COG3209 Rhs family protein
AS891_RS03105	COG2755	lipolytic protein G-D-S-L family
AS891_RS03105	COG3401	FG-GAP repeat protein
AS891_RS03110	COG0513	Belongs to the DEAD box helicase family
AS891_RS03115	COG2270	Major facilitator Superfamily
AS891_RS03125	COG3711	transcriptional antiterminator
AS891_RS03130	COG2273	Hydrolase Family 16
AS891_RS03135	COG2851	Citrate transporter
AS891_RS03140	COG0753	catalase activity
AS891_RS03140	COG0693	protein deglycase activity
AS891_RS03160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS891_RS03165	COG0500	methyltransferase
AS891_RS03175	COG2610	gluconate transmembrane transporter activity
AS891_RS03180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AS891_RS03185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AS891_RS03190	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS03195	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AS891_RS03200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AS891_RS03205	COG4894	glucomannan catabolic process
AS891_RS03220	COG2195	Cleaves the N-terminal amino acid of tripeptides
AS891_RS03225	COG2197	response regulator
AS891_RS03230	COG4585	Histidine kinase
AS891_RS03240	COG0583	DNA-binding transcription factor activity
AS891_RS03245	COG1881	PFAM PEBP family protein
AS891_RS03250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AS891_RS03260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_RS03265	COG1012	belongs to the aldehyde dehydrogenase family
AS891_RS03270	COG2508	Transcriptional regulator
AS891_RS03275	COG3842	ATPase activity
AS891_RS03280	COG0726	polysaccharide deacetylase
AS891_RS03290	COG0501	Belongs to the peptidase M48B family
AS891_RS03295	COG3493	citrate carrier protein
AS891_RS03300	COG1271	oxidase subunit
AS891_RS03305	COG1294	oxidase, subunit
AS891_RS03310	COG4988	ABC transporter
AS891_RS03315	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AS891_RS03320	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AS891_RS03325	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AS891_RS03330	COG1595	DNA-templated transcription, initiation
AS891_RS03350	COG1131	(ABC) transporter
AS891_RS03355	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AS891_RS03360	COG2814	Major facilitator Superfamily
AS891_RS03365	COG0753	catalase activity
AS891_RS03370	COG2094	Belongs to the DNA glycosylase MPG family
AS891_RS03380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_RS03380	COG3711	transcriptional antiterminator
AS891_RS03385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS891_RS03390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS891_RS03395	COG1447	Phosphotransferase system cellobiose-specific component IIA
AS891_RS03400	COG1486	melibiose metabolic process
AS891_RS03405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS891_RS03410	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AS891_RS03415	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AS891_RS03420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS891_RS03425	COG1696	Membrane protein involved in D-alanine export
AS891_RS03430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_RS03445	COG1575	Belongs to the MenA family. Type 1 subfamily
AS891_RS03450	COG2357	RelA SpoT domain protein
AS891_RS03455	COG2234	aminopeptidase activity
AS891_RS03460	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AS891_RS03465	COG1846	Transcriptional regulator
AS891_RS03470	COG5522	Integral membrane protein (intg_mem_TP0381)
AS891_RS03475	COG1442	glycosyl transferase family 8
AS891_RS03480	COG3711	transcriptional antiterminator
AS891_RS03485	COG1263	PTS System
AS891_RS03485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_RS03490	COG1404	Belongs to the peptidase S8 family
AS891_RS03495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS891_RS03505	COG0346	lactoylglutathione lyase activity
AS891_RS03510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AS891_RS03515	COG4895	conserved protein (DUF2196)
AS891_RS03520	COG2814	Major facilitator Superfamily
AS891_RS03525	COG1346	cytolysis
AS891_RS03530	COG1380	Effector of murein hydrolase LrgA
AS891_RS03535	COG0583	DNA-binding transcription factor activity
AS891_RS03540	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AS891_RS03545	COG0352	thiamine-phosphate diphosphorylase activity
AS891_RS03550	COG0672	)-iron permease
AS891_RS03555	COG2822	iron ion transport
AS891_RS03560	COG2837	iron assimilation
AS891_RS03565	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS891_RS03570	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS891_RS03575	COG3162	membrane
AS891_RS03590	COG2246	polysaccharide biosynthetic process
AS891_RS03595	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AS891_RS03600	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AS891_RS03605	COG2261	transglycosylase associated protein
AS891_RS03610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AS891_RS03615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS891_RS03620	COG1845	cytochrome c oxidase, subunit III
AS891_RS03625	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AS891_RS03635	COG0772	Belongs to the SEDS family
AS891_RS03640	COG0778	Nitroreductase
AS891_RS03645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_RS03650	COG1404	Belongs to the peptidase S8 family
AS891_RS03660	COG3711	transcriptional antiterminator
AS891_RS03665	COG2116	formate transmembrane transporter activity
AS891_RS03670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_RS03670	COG1263	PTS System
AS891_RS03675	COG1621	beta-fructofuranosidase activity
AS891_RS03685	COG0351	phosphomethylpyrimidine kinase
AS891_RS03690	COG1695	Transcriptional regulator
AS891_RS03705	COG1216	Glycosyl transferase, family 2
AS891_RS03710	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AS891_RS03715	COG1012	belongs to the aldehyde dehydrogenase family
AS891_RS03725	COG2233	PERMEase
AS891_RS03730	COG2363	Small membrane protein
AS891_RS03745	COG0463	Glycosyl transferase, family 2
AS891_RS03750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS891_RS03755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS891_RS03760	COG0456	acetyltransferase
AS891_RS03765	COG2089	acid synthase
AS891_RS03770	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AS891_RS03775	COG3980	spore coat polysaccharide biosynthesis protein
AS891_RS03780	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AS891_RS03785	COG1088	dTDP-glucose 4,6-dehydratase activity
AS891_RS03790	COG1091	dTDP-4-dehydrorhamnose reductase activity
AS891_RS03795	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AS891_RS03805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS891_RS03810	COG1012	belongs to the aldehyde dehydrogenase family
AS891_RS03815	COG4187	Peptidase family M20/M25/M40
AS891_RS03820	COG0833	amino acid
AS891_RS03825	COG2814	Major facilitator Superfamily
AS891_RS03830	COG0077	Prephenate dehydratase
AS891_RS03835	COG1917	Cupin 2, conserved barrel domain protein
AS891_RS03840	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS03845	COG0151	Belongs to the GarS family
AS891_RS03850	COG2814	Major facilitator Superfamily
AS891_RS03855	COG0436	Aminotransferase
AS891_RS03860	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS03865	COG3253	May function as heme-dependent peroxidase
AS891_RS03870	COG0280	phosphate acetyltransferase
AS891_RS03875	COG0583	DNA-binding transcription factor activity
AS891_RS03880	COG0095	Lipoate-protein ligase
AS891_RS03885	COG0697	spore germination
AS891_RS03895	COG4844	belongs to the
AS891_RS03900	COG1078	dGTPase activity
AS891_RS03905	COG3465	dGTPase activity
AS891_RS03910	COG1959	2 iron, 2 sulfur cluster binding
AS891_RS03915	COG0477	Major facilitator Superfamily
AS891_RS03925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AS891_RS03930	COG1846	Transcriptional regulator
AS891_RS03935	COG1942	4-Oxalocrotonate Tautomerase
AS891_RS03940	COG1994	Peptidase M50
AS891_RS03950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS891_RS03955	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AS891_RS03960	COG0010	Belongs to the arginase family
AS891_RS03965	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AS891_RS03975	COG0457	Tetratricopeptide repeat
AS891_RS03985	COG3391	amine dehydrogenase activity
AS891_RS03990	COG3391	amine dehydrogenase activity
AS891_RS04000	COG0612	Peptidase, M16
AS891_RS04005	COG0612	Peptidase, M16
AS891_RS04010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS891_RS04015	COG1131	(ABC) transporter
AS891_RS04025	COG0535	radical SAM domain protein
AS891_RS04035	COG4506	Protein conserved in bacteria
AS891_RS04040	COG0018	arginyl-trna synthetase
AS891_RS04045	COG2223	nitrite transmembrane transporter activity
AS891_RS04050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS891_RS04060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS891_RS04065	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AS891_RS04070	COG1140	nitrate reductase beta subunit
AS891_RS04075	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AS891_RS04080	COG2181	nitrate reductase activity
AS891_RS04085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS891_RS04090	COG1132	(ABC) transporter
AS891_RS04095	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS891_RS04105	COG4294	response to UV
AS891_RS04110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS891_RS04115	COG2181	nitrate reductase activity
AS891_RS04115	COG0247	lactate metabolic process
AS891_RS04120	COG1960	acyl-CoA dehydrogenase activity
AS891_RS04125	COG3343	RNA polymerase activity
AS891_RS04130	COG0504	CTP synthase activity
AS891_RS04135	COG4821	SIS domain
AS891_RS04140	COG2204	response regulator
AS891_RS04145	COG0191	fructose-bisphosphate aldolase activity
AS891_RS04150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS891_RS04155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS891_RS04160	COG1494	fructose-1,6-bisphosphatase
AS891_RS04170	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AS891_RS04180	COG1435	thymidine kinase activity
AS891_RS04185	COG0281	malic enzyme
AS891_RS04190	COG0679	Auxin Efflux Carrier
AS891_RS04195	COG0789	Transcriptional regulator
AS891_RS04200	COG0346	lactoylglutathione lyase activity
AS891_RS04205	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AS891_RS04210	COG2890	protein-(glutamine-N5) methyltransferase activity
AS891_RS04230	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AS891_RS04235	COG0009	L-threonylcarbamoyladenylate synthase
AS891_RS04240	COG1971	Probably functions as a manganese efflux pump
AS891_RS04245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS891_RS04250	COG0698	ribose 5-phosphate isomerase
AS891_RS04255	COG4475	Protein of unknown function (DUF436)
AS891_RS04260	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AS891_RS04265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AS891_RS04275	COG0356	it plays a direct role in the translocation of protons across the membrane
AS891_RS04290	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AS891_RS04295	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AS891_RS04300	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AS891_RS04305	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AS891_RS04310	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AS891_RS04315	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AS891_RS04325	COG4836	Membrane
AS891_RS04335	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS891_RS04340	COG2385	sporulation resulting in formation of a cellular spore
AS891_RS04345	COG2304	oxidoreductase activity
AS891_RS04355	COG2304	oxidoreductase activity
AS891_RS04365	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AS891_RS04370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AS891_RS04375	COG0457	Tetratricopeptide repeat
AS891_RS04380	COG1994	Peptidase M50
AS891_RS04385	COG3237	CsbD-like
AS891_RS04395	COG0831	urea catabolic process
AS891_RS04400	COG0832	Belongs to the urease beta subunit family
AS891_RS04405	COG0804	urea catabolic process
AS891_RS04410	COG1959	2 iron, 2 sulfur cluster binding
AS891_RS04415	COG2910	NAD(P)H-binding
AS891_RS04425	COG0789	Transcriptional regulator
AS891_RS04430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS891_RS04450	COG1247	-acetyltransferase
AS891_RS04455	COG0739	heme binding
AS891_RS04465	COG0671	phosphoesterase, PA-phosphatase related
AS891_RS04470	COG0347	Belongs to the P(II) protein family
AS891_RS04475	COG0004	ammonium transporteR
AS891_RS04485	COG1335	isochorismatase
AS891_RS04490	COG0477	Major facilitator Superfamily
AS891_RS04495	COG1953	Uracil, thiamine, allantoin
AS891_RS04500	COG3420	alginic acid biosynthetic process
AS891_RS04505	COG2814	Major facilitator Superfamily
AS891_RS04510	COG1846	Transcriptional regulator
AS891_RS04515	COG1609	Transcriptional regulator
AS891_RS04520	COG1077	Cell shape determining protein MreB Mrl
AS891_RS04525	COG4786	Flagellar basal body rod
AS891_RS04530	COG4786	Flagellar basal body rod
AS891_RS04535	COG0457	Tetratricopeptide repeat
AS891_RS04540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AS891_RS04545	COG1970	mechanosensitive ion channel activity
AS891_RS04550	COG2972	Histidine kinase
AS891_RS04550	COG0745	RESPONSE REGULATOR receiver
AS891_RS04560	COG3764	Sortase (surface protein transpeptidase)
AS891_RS04575	COG0629	single-stranded DNA binding
AS891_RS04580	COG1349	DNA-binding transcription factor activity
AS891_RS04585	COG0561	phosphatase activity
AS891_RS04590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS891_RS04595	COG4715	Zinc finger, swim domain protein
AS891_RS04605	COG3944	biosynthesis protein
AS891_RS04610	COG0489	protein tyrosine kinase activity
AS891_RS04615	COG4464	protein tyrosine phosphatase activity
AS891_RS04620	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS891_RS04625	COG3878	Protein conserved in bacteria
AS891_RS04640	COG5444	nuclease activity
AS891_RS04645	COG2849	repeat protein
AS891_RS04650	COG1515	deoxyribonuclease V activity
AS891_RS04655	COG0583	DNA-binding transcription factor activity
AS891_RS04660	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS891_RS04670	COG2059	Chromate
AS891_RS04675	COG2059	Chromate
AS891_RS04680	COG1522	sequence-specific DNA binding
AS891_RS04685	COG0405	Gamma-glutamyltransferase
AS891_RS04695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS891_RS04705	COG5337	Spore coat protein CotH
AS891_RS04720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS891_RS04725	COG0583	DNA-binding transcription factor activity
AS891_RS04730	COG0028	Belongs to the TPP enzyme family
AS891_RS04735	COG3527	Alpha-acetolactate decarboxylase
AS891_RS04740	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS891_RS04750	COG3103	Sh3 type 3 domain protein
AS891_RS04755	COG1879	ABC-type sugar transport system periplasmic component
AS891_RS04760	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS891_RS04765	COG1129	ABC transporter
AS891_RS04770	COG1869	D-ribose catabolic process
AS891_RS04775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS891_RS04780	COG1609	Transcriptional regulator
AS891_RS04785	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AS891_RS04795	COG2843	Capsule synthesis protein
AS891_RS04805	COG0791	NLP P60 protein
AS891_RS04810	COG0561	phosphatase activity
AS891_RS04815	COG1316	TRANSCRIPTIONal
AS891_RS04820	COG2814	Major facilitator Superfamily
AS891_RS04830	COG0814	amino acid
AS891_RS04835	COG0697	spore germination
AS891_RS04845	COG1482	cell wall glycoprotein biosynthetic process
AS891_RS04850	COG4193	domain, Protein
AS891_RS04860	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS891_RS04865	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AS891_RS04870	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AS891_RS04875	COG0438	transferase activity, transferring glycosyl groups
AS891_RS04880	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS891_RS04885	COG1682	transport, permease protein
AS891_RS04890	COG1134	teichoic acid transport
AS891_RS04905	COG0463	Glycosyl transferase, family 2
AS891_RS04910	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS891_RS04910	COG1215	transferase activity, transferring glycosyl groups
AS891_RS04915	COG1682	transport, permease protein
AS891_RS04920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS891_RS04925	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AS891_RS04930	COG1316	TRANSCRIPTIONal
AS891_RS04940	COG2247	cell wall binding repeat
AS891_RS04940	COG2385	sporulation resulting in formation of a cellular spore
AS891_RS04945	COG2247	cell wall binding repeat
AS891_RS04945	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS891_RS04955	COG2244	polysaccharide biosynthetic process
AS891_RS04960	COG0297	glycogen (starch) synthase activity
AS891_RS04960	COG0438	transferase activity, transferring glycosyl groups
AS891_RS04965	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS891_RS04970	COG3307	-O-antigen
AS891_RS04975	COG3206	protein involved in exopolysaccharide biosynthesis
AS891_RS04980	COG1215	transferase activity, transferring glycosyl groups
AS891_RS04985	COG0438	transferase activity, transferring glycosyl groups
AS891_RS04990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS891_RS04995	COG1316	TRANSCRIPTIONal
AS891_RS05000	COG1739	Uncharacterized protein family UPF0029
AS891_RS05005	COG4585	Histidine kinase
AS891_RS05010	COG2197	response regulator
AS891_RS05015	COG1307	EDD domain protein, DegV family
AS891_RS05020	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AS891_RS05030	COG1040	competence protein
AS891_RS05040	COG2747	anti-sigma28 factor FlgM
AS891_RS05045	COG3418	PFAM FlgN family protein
AS891_RS05050	COG1256	bacterial-type flagellum assembly
AS891_RS05050	COG4786	Flagellar basal body rod
AS891_RS05055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AS891_RS05065	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AS891_RS05070	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AS891_RS05075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AS891_RS05080	COG1334	flagellar protein FlaG
AS891_RS05085	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AS891_RS05090	COG1516	flagellar protein fliS
AS891_RS05105	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AS891_RS05110	COG0653	protein targeting
AS891_RS05115	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AS891_RS05120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_RS05125	COG2010	Cytochrome c
AS891_RS05130	COG2884	Cell division ATP-binding protein ftsE
AS891_RS05135	COG2177	Part of the ABC transporter FtsEX involved in
AS891_RS05140	COG0793	Belongs to the peptidase S41A family
AS891_RS05140	COG3409	Peptidoglycan-binding domain 1 protein
AS891_RS05150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS891_RS05155	COG2814	Major facilitator Superfamily
AS891_RS05160	COG1309	transcriptional regulator
AS891_RS05165	COG3848	Pyruvate phosphate dikinase
AS891_RS05165	COG0574	Belongs to the PEP-utilizing enzyme family
AS891_RS05170	COG4897	Protein conserved in bacteria
AS891_RS05175	COG0556	nucleotide-excision repair
AS891_RS05180	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS891_RS05185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AS891_RS05200	COG3595	metallopeptidase activity
AS891_RS05205	COG1983	PspC domain protein
AS891_RS05210	COG1950	PFAM Membrane protein of
AS891_RS05215	COG2814	Major facilitator Superfamily
AS891_RS05220	COG1846	Transcriptional regulator
AS891_RS05230	COG2124	cytochrome p450
AS891_RS05235	COG1846	Transcriptional regulator
AS891_RS05240	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS891_RS05245	COG2188	Transcriptional regulator
AS891_RS05250	COG0363	glucosamine-6-phosphate deaminase activity
AS891_RS05255	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AS891_RS05260	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AS891_RS05265	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AS891_RS05270	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AS891_RS05275	COG0546	phosphoglycolate phosphatase activity
AS891_RS05280	COG0110	maltose O-acetyltransferase activity
AS891_RS05285	COG5297	Belongs to the glycosyl hydrolase family 6
AS891_RS05290	COG4990	cell redox homeostasis
AS891_RS05295	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AS891_RS05300	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AS891_RS05305	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AS891_RS05310	COG0131	Imidazoleglycerol-phosphate dehydratase
AS891_RS05315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AS891_RS05320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AS891_RS05325	COG0107	imidazoleglycerol-phosphate synthase activity
AS891_RS05330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AS891_RS05330	COG0140	phosphoribosyl-ATP diphosphatase activity
AS891_RS05350	COG1132	(ABC) transporter
AS891_RS05355	COG0457	Tetratricopeptide repeat
AS891_RS05360	COG0791	NLP P60 protein
AS891_RS05360	COG3883	PFAM NLP P60 protein
AS891_RS05365	COG0492	ferredoxin-NADP+ reductase activity
AS891_RS05370	COG1051	belongs to the nudix hydrolase family
AS891_RS05375	COG1660	Displays ATPase and GTPase activities
AS891_RS05380	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AS891_RS05385	COG1481	regulation of sporulation
AS891_RS05390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_RS05395	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AS891_RS05405	COG0745	RESPONSE REGULATOR receiver
AS891_RS05410	COG5002	protein histidine kinase activity
AS891_RS05415	COG1136	(ABC) transporter
AS891_RS05420	COG0577	efflux transmembrane transporter activity
AS891_RS05425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS891_RS05430	COG0288	reversible hydration of carbon dioxide
AS891_RS05435	COG0659	secondary active sulfate transmembrane transporter activity
AS891_RS05440	COG1694	Mazg nucleotide pyrophosphohydrolase
AS891_RS05445	COG1611	Belongs to the LOG family
AS891_RS05450	COG1609	Transcriptional regulator
AS891_RS05455	COG0366	Alpha amylase catalytic
AS891_RS05460	COG2182	Extracellular solute-binding protein
AS891_RS05465	COG1175	transmembrane transport
AS891_RS05470	COG3833	ABC-type maltose transport systems, permease component
AS891_RS05475	COG5521	maltodextrose utilization protein MalA
AS891_RS05480	COG1554	hydrolase, family 65, central catalytic
AS891_RS05485	COG0366	Alpha amylase catalytic
AS891_RS05490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS891_RS05495	COG0740	serine-type endopeptidase activity
AS891_RS05505	COG3621	Patatin-like phospholipase
AS891_RS05510	COG0277	FAD linked oxidase domain protein
AS891_RS05520	COG2076	Multidrug Resistance protein
AS891_RS05525	COG2076	Multidrug Resistance protein
AS891_RS05530	COG1309	transcriptional regulator
AS891_RS05535	COG0531	amino acid
AS891_RS05540	COG1621	beta-fructofuranosidase activity
AS891_RS05545	COG1621	beta-fructofuranosidase activity
AS891_RS05550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS891_RS05555	COG1794	racemase activity, acting on amino acids and derivatives
AS891_RS05565	COG3479	Phenolic acid decarboxylase
AS891_RS05575	COG2272	Belongs to the type-B carboxylesterase lipase family
AS891_RS05580	COG1396	sequence-specific DNA binding
AS891_RS05585	COG3944	biosynthesis protein
AS891_RS05590	COG0489	protein tyrosine kinase activity
AS891_RS05595	COG1086	Polysaccharide biosynthesis protein
AS891_RS05600	COG0438	transferase activity, transferring glycosyl groups
AS891_RS05605	COG1215	transferase activity, transferring glycosyl groups
AS891_RS05610	COG0438	transferase activity, transferring glycosyl groups
AS891_RS05620	COG1216	Glycosyl transferase, family 2
AS891_RS05625	COG5039	Polysaccharide pyruvyl transferase
AS891_RS05630	COG1216	Glycosyl transferase, family 2
AS891_RS05635	COG2244	polysaccharide biosynthetic process
AS891_RS05640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AS891_RS05645	COG0110	maltose O-acetyltransferase activity
AS891_RS05650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS891_RS05655	COG5039	Polysaccharide pyruvyl transferase
AS891_RS05665	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AS891_RS05670	COG1620	l-lactate permease
AS891_RS05675	COG2186	Transcriptional regulator
AS891_RS05680	COG1609	Transcriptional regulator
AS891_RS05685	COG2182	Extracellular solute-binding protein
AS891_RS05690	COG1175	transmembrane transport
AS891_RS05695	COG3833	ABC-type maltose transport systems, permease component
AS891_RS05700	COG1874	Beta-galactosidase
AS891_RS05705	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AS891_RS05710	COG2208	phosphoserine phosphatase activity
AS891_RS05715	COG0596	Alpha beta hydrolase
AS891_RS05720	COG1131	(ABC) transporter
AS891_RS05725	COG0842	Transport permease protein
AS891_RS05730	COG4585	Histidine kinase
AS891_RS05735	COG2197	response regulator
AS891_RS05740	COG0247	lactate metabolic process
AS891_RS05745	COG1139	Iron-sulfur cluster binding protein
AS891_RS05750	COG1556	Lactate utilization protein
AS891_RS05755	COG3858	chitin binding
AS891_RS05760	COG1113	amino acid transport
AS891_RS05765	COG0697	spore germination
AS891_RS05770	COG0583	DNA-binding transcription factor activity
AS891_RS05775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_RS05780	COG1609	Transcriptional regulator
AS891_RS05785	COG2814	Major facilitator Superfamily
AS891_RS05790	COG2390	Transcriptional regulator
AS891_RS05795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AS891_RS05805	COG0126	phosphoglycerate kinase activity
AS891_RS05810	COG0149	triose-phosphate isomerase activity
AS891_RS05815	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AS891_RS05820	COG0148	phosphopyruvate hydratase activity
AS891_RS05825	COG0456	acetyltransferase
AS891_RS05830	COG4640	response to antibiotic
AS891_RS05835	COG3064	Membrane
AS891_RS05845	COG2095	MarC family integral membrane protein
AS891_RS05850	COG1510	regulation of RNA biosynthetic process
AS891_RS05855	COG1125	glycine betaine transport
AS891_RS05855	COG0517	IMP dehydrogenase activity
AS891_RS05860	COG1174	glycine betaine transport
AS891_RS05865	COG1732	Glycine betaine
AS891_RS05870	COG1174	glycine betaine transport
AS891_RS05875	COG0640	Transcriptional regulator
AS891_RS05880	COG5658	integral membrane protein
AS891_RS05900	COG1510	regulation of RNA biosynthetic process
AS891_RS05905	COG1125	glycine betaine transport
AS891_RS05905	COG0517	IMP dehydrogenase activity
AS891_RS05910	COG1174	glycine betaine transport
AS891_RS05915	COG1732	Glycine betaine
AS891_RS05920	COG1174	glycine betaine transport
AS891_RS05925	COG0840	transmembrane signaling receptor activity
AS891_RS05930	COG1733	regulation of RNA biosynthetic process
AS891_RS05935	COG1396	sequence-specific DNA binding
AS891_RS05940	COG1396	sequence-specific DNA binding
AS891_RS05945	COG1476	TRANSCRIPTIONal
AS891_RS05950	COG0596	Alpha beta hydrolase
AS891_RS05955	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS891_RS05960	COG1647	Serine aminopeptidase, S33
AS891_RS05965	COG0557	exoribonuclease II activity
AS891_RS05970	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AS891_RS05980	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS05985	COG1309	transcriptional regulator
AS891_RS05990	COG2076	Multidrug Resistance protein
AS891_RS06000	COG1289	transmembrane transporter activity
AS891_RS06005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AS891_RS06010	COG0673	inositol 2-dehydrogenase activity
AS891_RS06015	COG1937	Protein conserved in bacteria
AS891_RS06020	COG2608	mercury ion transmembrane transporter activity
AS891_RS06025	COG2217	Heavy metal translocating P-type atpase
AS891_RS06030	COG2217	Heavy metal translocating P-type atpase
AS891_RS06035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AS891_RS06040	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AS891_RS06045	COG2860	membrane
AS891_RS06050	COG3973	AAA domain
AS891_RS06055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AS891_RS06060	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS891_RS06065	COG0025	NhaP-type Na H and K H
AS891_RS06075	COG0656	L-ascorbic acid biosynthetic process
AS891_RS06080	COG4149	molybdate abc transporter
AS891_RS06085	COG0725	ABC transporter, periplasmic molybdate-binding protein
AS891_RS06090	COG1910	domain protein
AS891_RS06095	COG1368	sulfuric ester hydrolase activity
AS891_RS06100	COG1988	membrane-bound metal-dependent
AS891_RS06110	COG0531	amino acid
AS891_RS06120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS891_RS06125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_RS06130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_RS06135	COG1120	ATPase activity
AS891_RS06140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AS891_RS06145	COG1136	(ABC) transporter
AS891_RS06150	COG0577	efflux transmembrane transporter activity
AS891_RS06160	COG2140	Oxalate decarboxylase
AS891_RS06170	COG1191	sigma factor activity
AS891_RS06180	COG0745	RESPONSE REGULATOR receiver
AS891_RS06185	COG2205	protein histidine kinase activity
AS891_RS06190	COG3386	PFAM SMP-30 Gluconolaconase
AS891_RS06195	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS06200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS891_RS06205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_RS06210	COG1120	ATPase activity
AS891_RS06215	COG2096	Adenosyltransferase
AS891_RS06220	COG2814	Major facilitator Superfamily
AS891_RS06225	COG4758	membrane
AS891_RS06230	COG1842	Phage shock protein A
AS891_RS06235	COG3595	metallopeptidase activity
AS891_RS06240	COG4758	membrane
AS891_RS06245	COG4585	Histidine kinase
AS891_RS06250	COG2197	response regulator
AS891_RS06260	COG0814	amino acid
AS891_RS06265	COG0697	spore germination
AS891_RS06275	COG0114	fumarate hydratase activity
AS891_RS06280	COG1309	transcriptional regulator
AS891_RS06290	COG2205	protein histidine kinase activity
AS891_RS06290	COG2770	Histidine kinase
AS891_RS06295	COG0745	RESPONSE REGULATOR receiver
AS891_RS06300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS891_RS06305	COG0783	Belongs to the Dps family
AS891_RS06310	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS06330	COG1120	ATPase activity
AS891_RS06340	COG0583	DNA-binding transcription factor activity
AS891_RS06345	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS06350	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS06355	COG1942	4-Oxalocrotonate Tautomerase
AS891_RS06360	COG0477	Major facilitator Superfamily
AS891_RS06365	COG1846	Transcriptional regulator
AS891_RS06370	COG5577	PFAM Coat F domain
AS891_RS06380	COG0506	proline dehydrogenase activity
AS891_RS06390	COG1024	Enoyl-CoA hydratase
AS891_RS06390	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS891_RS06395	COG0183	Belongs to the thiolase family
AS891_RS06400	COG1960	acyl-CoA dehydrogenase activity
AS891_RS06405	COG1393	Belongs to the ArsC family
AS891_RS06410	COG0509	glycine decarboxylation via glycine cleavage system
AS891_RS06420	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AS891_RS06425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_RS06435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AS891_RS06440	COG2011	ABC-type metal ion transport system permease component
AS891_RS06445	COG1464	Belongs to the NlpA lipoprotein family
AS891_RS06450	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS891_RS06460	COG0396	ATPase activity
AS891_RS06465	COG0719	Fe-S assembly protein
AS891_RS06470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS891_RS06475	COG0822	iron-sulfur transferase activity
AS891_RS06480	COG0719	Fe-S assembly protein
AS891_RS06485	COG0640	Transcriptional regulator
AS891_RS06490	COG0346	lactoylglutathione lyase activity
AS891_RS06505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS891_RS06510	COG0322	excinuclease ABC activity
AS891_RS06515	COG2222	sugar isomerase
AS891_RS06520	COG1653	transport
AS891_RS06525	COG1175	transmembrane transport
AS891_RS06530	COG0395	ABC-type sugar transport system, permease component
AS891_RS06535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS891_RS06540	COG2188	Transcriptional regulator
AS891_RS06545	COG3842	ATPase activity
AS891_RS06550	COG2356	endonuclease I
AS891_RS06560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS891_RS06565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AS891_RS06570	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AS891_RS06575	COG2068	MobA-Related Protein
AS891_RS06580	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AS891_RS06585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AS891_RS06590	COG2080	2 iron, 2 sulfur cluster binding
AS891_RS06600	COG2351	hydroxyisourate hydrolase activity
AS891_RS06605	COG3648	Uricase
AS891_RS06605	COG3195	allantoin biosynthetic process
AS891_RS06610	COG2233	PERMEase
AS891_RS06615	COG2233	PERMEase
AS891_RS06620	COG2508	Transcriptional regulator
AS891_RS06625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AS891_RS06635	COG1801	Protein of unknown function DUF72
AS891_RS06640	COG0730	response to heat
AS891_RS06645	COG0737	Belongs to the 5'-nucleotidase family
AS891_RS06650	COG3377	Domain of unknown function (DUF1805)
AS891_RS06660	COG0739	heme binding
AS891_RS06665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AS891_RS06675	COG4470	Protein conserved in bacteria
AS891_RS06680	COG2445	Protein of unknown function DUF86
AS891_RS06685	COG0647	UMP catabolic process
AS891_RS06690	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AS891_RS06695	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS891_RS06700	COG0460	homoserine dehydrogenase
AS891_RS06705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AS891_RS06710	COG0083	homoserine kinase activity
AS891_RS06715	COG0823	Involved in the tonB-independent uptake of proteins
AS891_RS06715	COG4946	Tricorn protease homolog
AS891_RS06715	COG1506	peptidase
AS891_RS06720	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AS891_RS06725	COG4837	Protein of unknown function (DUF1462)
AS891_RS06730	COG1252	NADH dehydrogenase
AS891_RS06735	COG4844	belongs to the
AS891_RS06740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS891_RS06745	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AS891_RS06750	COG0316	Belongs to the HesB IscA family
AS891_RS06755	COG0456	acetyltransferase
AS891_RS06760	COG2808	Putative FMN-binding domain
AS891_RS06765	COG0516	GMP reductase activity
AS891_RS06775	COG0492	ferredoxin-NADP+ reductase activity
AS891_RS06780	COG1252	NADH dehydrogenase
AS891_RS06795	COG3584	3D domain protein
AS891_RS06800	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AS891_RS06805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AS891_RS06810	COG2056	Na+-H+ antiporter family
AS891_RS06815	COG1268	BioY protein
AS891_RS06820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS891_RS06825	COG2819	hydrolase of the alpha beta superfamily
AS891_RS06830	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS06835	COG1169	isochorismate synthase
AS891_RS06840	COG1021	2,3-dihydroxybenzoate-AMP ligase
AS891_RS06845	COG3433	isochorismatase activity
AS891_RS06845	COG1535	isochorismatase
AS891_RS06850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_RS06855	COG3251	PFAM MbtH domain protein
AS891_RS06860	COG5634	Uncharacterized conserved protein (DUF2278)
AS891_RS06865	COG0686	Belongs to the AlaDH PNT family
AS891_RS06870	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AS891_RS06870	COG2508	Transcriptional regulator
AS891_RS06875	COG4842	Belongs to the WXG100 family
AS891_RS06880	COG5417	Belongs to the EsaB family
AS891_RS06885	COG4499	WXG100 protein secretion system (Wss), protein YukC
AS891_RS06890	COG0433	COG0433 Predicted ATPase
AS891_RS06890	COG1674	ftsk spoiiie
AS891_RS06895	COG1511	domain protein
AS891_RS06905	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS06910	COG1418	mRNA catabolic process
AS891_RS06925	COG0628	permease
AS891_RS06940	COG5506	Protein of unknown function (DUF1694)
AS891_RS06945	COG1335	isochorismatase
AS891_RS06950	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AS891_RS06955	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AS891_RS06970	COG0142	geranyltranstransferase activity
AS891_RS06980	COG4585	Histidine kinase
AS891_RS06985	COG2197	response regulator
AS891_RS06990	COG2050	protein possibly involved in aromatic compounds catabolism
AS891_RS06995	COG1320	monovalent cation:proton antiporter activity
AS891_RS07000	COG2212	antiporter activity
AS891_RS07005	COG1863	multisubunit Na H antiporter MnhE subunit
AS891_RS07010	COG0651	ATP synthesis coupled electron transport
AS891_RS07015	COG1006	Multisubunit Na H antiporter MnhC subunit
AS891_RS07020	COG2111	Na H antiporter
AS891_RS07025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS891_RS07025	COG2111	Na H antiporter
AS891_RS07035	COG3493	citrate carrier protein
AS891_RS07040	COG1079	Belongs to the binding-protein-dependent transport system permease family
AS891_RS07045	COG4603	Belongs to the binding-protein-dependent transport system permease family
AS891_RS07050	COG3845	ABC transporter
AS891_RS07055	COG1744	ABC transporter substrate-binding protein PnrA-like
AS891_RS07060	COG4565	transcriptional regulatory protein
AS891_RS07065	COG3290	protein histidine kinase activity
AS891_RS07075	COG3011	Protein conserved in bacteria
AS891_RS07080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS891_RS07085	COG2814	Major facilitator Superfamily
AS891_RS07095	COG5018	Exonuclease
AS891_RS07105	COG2205	protein histidine kinase activity
AS891_RS07110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AS891_RS07120	COG2267	carboxylic ester hydrolase activity
AS891_RS07125	COG1522	sequence-specific DNA binding
AS891_RS07130	COG0436	Aminotransferase
AS891_RS07135	COG1098	S1 RNA binding domain
AS891_RS07140	COG2155	Conserved Protein
AS891_RS07145	COG1979	alcohol dehydrogenase
AS891_RS07150	COG1979	alcohol dehydrogenase
AS891_RS07155	COG0166	Belongs to the GPI family
AS891_RS07170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AS891_RS07185	COG2738	Putative neutral zinc metallopeptidase
AS891_RS07190	COG1253	flavin adenine dinucleotide binding
AS891_RS07195	COG0366	Alpha amylase catalytic
AS891_RS07200	COG0432	Pfam Uncharacterised protein family UPF0047
AS891_RS07215	COG0840	transmembrane signaling receptor activity
AS891_RS07220	COG0840	transmembrane signaling receptor activity
AS891_RS07225	COG0840	transmembrane signaling receptor activity
AS891_RS07230	COG0840	transmembrane signaling receptor activity
AS891_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS07235	COG3347	Dehydrogenase
AS891_RS07240	COG1349	DNA-binding transcription factor activity
AS891_RS07245	COG1070	Carbohydrate kinase
AS891_RS07250	COG3254	rhamnose metabolic process
AS891_RS07255	COG4806	L-rhamnose isomerase
AS891_RS07260	COG0673	inositol 2-dehydrogenase activity
AS891_RS07265	COG0628	permease
AS891_RS07270	COG1968	undecaprenyl-diphosphatase activity
AS891_RS07280	COG5553	Cysteine dioxygenase type I
AS891_RS07285	COG0477	Major facilitator Superfamily
AS891_RS07290	COG1705	Flagellar rod assembly protein muramidase FlgJ
AS891_RS07295	COG4682	membrane
AS891_RS07300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS891_RS07305	COG0569	domain protein
AS891_RS07315	COG1510	regulation of RNA biosynthetic process
AS891_RS07320	COG1012	belongs to the aldehyde dehydrogenase family
AS891_RS07325	COG1454	alcohol dehydrogenase
AS891_RS07335	COG2318	DinB family
AS891_RS07340	COG1585	Membrane protein implicated in regulation of membrane protease activity
AS891_RS07345	COG2268	Band 7 protein
AS891_RS07350	COG1247	-acetyltransferase
AS891_RS07355	COG3859	Proton-coupled thiamine transporter YuaJ
AS891_RS07485	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AS891_RS07490	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AS891_RS07495	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AS891_RS07500	COG0297	glycogen (starch) synthase activity
AS891_RS07505	COG0058	SHG alpha-glucan phosphorylase activity
AS891_RS07510	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AS891_RS07515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS891_RS07520	COG0438	transferase activity, transferring glycosyl groups
AS891_RS07525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS891_RS07535	COG0438	transferase activity, transferring glycosyl groups
AS891_RS07540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS891_RS07545	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS891_RS07550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS891_RS07555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS891_RS07560	COG1169	isochorismate synthase
AS891_RS07565	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AS891_RS07570	COG0596	Alpha beta hydrolase
AS891_RS07575	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AS891_RS07580	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_RS07585	COG4948	Mandelate Racemase Muconate Lactonizing
AS891_RS07590	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS891_RS07595	COG1121	(ABC) transporter
AS891_RS07600	COG1321	iron dependent repressor
AS891_RS07600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS891_RS07605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS891_RS07615	COG1294	oxidase, subunit
AS891_RS07620	COG1271	oxidase subunit
AS891_RS07625	COG0254	rRNA binding
AS891_RS07630	COG0288	reversible hydration of carbon dioxide
AS891_RS07635	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AS891_RS07640	COG1854	S-ribosylhomocysteine lyase activity
AS891_RS07655	COG0783	Belongs to the Dps family
AS891_RS07660	COG4824	toxin secretion phage lysis holin
AS891_RS07665	COG0494	nUDIX hydrolase
AS891_RS07670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS891_RS07675	COG1116	anion transmembrane transporter activity
AS891_RS07680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS891_RS07685	COG1506	peptidase
AS891_RS07695	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AS891_RS07700	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AS891_RS07705	COG0367	asparagine synthase
AS891_RS07710	COG1113	amino acid transport
AS891_RS07715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AS891_RS07720	COG2267	carboxylic ester hydrolase activity
AS891_RS07730	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AS891_RS07735	COG1242	4 iron, 4 sulfur cluster binding
AS891_RS07750	COG1725	Transcriptional regulator
AS891_RS07755	COG1131	(ABC) transporter
AS891_RS07770	COG1136	(ABC) transporter
AS891_RS07775	COG0577	efflux transmembrane transporter activity
AS891_RS07780	COG0745	RESPONSE REGULATOR receiver
AS891_RS07785	COG2205	protein histidine kinase activity
AS891_RS07790	COG1136	(ABC) transporter
AS891_RS07795	COG0577	efflux transmembrane transporter activity
AS891_RS07800	COG2433	Pfam Transposase IS66
AS891_RS07805	COG2814	Major facilitator Superfamily
AS891_RS07810	COG2202	Pas domain
AS891_RS07810	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_RS07820	COG0495	leucyl-tRNA aminoacylation
AS891_RS07825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS891_RS07830	COG1486	melibiose metabolic process
AS891_RS07835	COG0395	ABC-type sugar transport system, permease component
AS891_RS07840	COG1175	transmembrane transport
AS891_RS07845	COG1653	transport
AS891_RS07850	COG1609	Transcriptional regulator
AS891_RS07855	COG1073	alpha beta
AS891_RS07860	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
AS891_RS07865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS891_RS07870	COG0156	8-amino-7-oxononanoate synthase activity
AS891_RS07875	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AS891_RS07880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AS891_RS07885	COG2124	cytochrome p450
AS891_RS07890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS891_RS07895	COG0395	ABC-type sugar transport system, permease component
AS891_RS07900	COG1653	transport
AS891_RS07905	COG2207	Transcriptional regulator
AS891_RS07910	COG4209	transmembrane transport
AS891_RS07915	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AS891_RS07920	COG1653	transport
AS891_RS07925	COG0673	inositol 2-dehydrogenase activity
AS891_RS07930	COG5578	integral membrane protein
AS891_RS07940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS891_RS07945	COG2081	HI0933 family
AS891_RS07950	COG2244	polysaccharide biosynthetic process
AS891_RS07955	COG1187	pseudouridine synthase activity
AS891_RS07960	COG1349	DNA-binding transcription factor activity
AS891_RS07965	COG1131	(ABC) transporter
AS891_RS07970	COG4473	ABC transporter
AS891_RS07975	COG2252	PERMEase
AS891_RS07980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS891_RS07985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS891_RS07990	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AS891_RS08000	COG1597	lipid kinase activity
AS891_RS08005	COG1523	belongs to the glycosyl hydrolase 13 family
AS891_RS08010	COG0510	thiamine kinase activity
AS891_RS08020	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AS891_RS08025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_RS08030	COG0281	malic enzyme
AS891_RS08035	COG5584	Small secreted protein
AS891_RS08040	COG1363	Peptidase, m42
AS891_RS08050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_RS08055	COG4848	Belongs to the UPF0354 family
AS891_RS08060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS891_RS08065	COG1674	ftsk spoiiie
AS891_RS08070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AS891_RS08075	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AS891_RS08080	COG4980	gas vesicle protein
AS891_RS08085	COG3118	belongs to the thioredoxin family
AS891_RS08090	COG1605	Chorismate mutase
AS891_RS08090	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AS891_RS08095	COG1609	Transcriptional regulator
AS891_RS08100	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AS891_RS08105	COG1360	Flagellar Motor Protein
AS891_RS08110	COG0123	including yeast histone deacetylase and acetoin utilization protein
AS891_RS08115	COG0517	IMP dehydrogenase activity
AS891_RS08120	COG0454	-acetyltransferase
AS891_RS08125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS891_RS08130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AS891_RS08140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AS891_RS08145	COG2203	Gaf domain
AS891_RS08145	COG2199	diguanylate cyclase activity
AS891_RS08150	COG1956	GAF domain-containing protein
AS891_RS08155	COG1309	transcriptional regulator
AS891_RS08160	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS891_RS08165	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AS891_RS08170	COG1114	Component of the transport system for branched-chain amino acids
AS891_RS08175	COG1104	cysteine desulfurase activity
AS891_RS08180	COG0301	tRNA thio-modification
AS891_RS08190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS891_RS08195	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AS891_RS08200	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AS891_RS08205	COG0616	signal peptide processing
AS891_RS08210	COG1714	RDD family
AS891_RS08220	COG3874	Sporulation protein YtfJ
AS891_RS08225	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AS891_RS08230	COG0827	DNA restriction-modification system
AS891_RS08235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AS891_RS08240	COG0521	Mo-molybdopterin cofactor biosynthetic process
AS891_RS08245	COG0137	argininosuccinate synthase activity
AS891_RS08250	COG0165	Argininosuccinate lyase
AS891_RS08260	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS08265	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AS891_RS08270	COG0583	DNA-binding transcription factor activity
AS891_RS08275	COG0454	-acetyltransferase
AS891_RS08280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_RS08285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_RS08290	COG0765	amino acid transport
AS891_RS08295	COG0765	amino acid transport
AS891_RS08300	COG1126	abc transporter atp-binding protein
AS891_RS08305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_RS08310	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AS891_RS08315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_RS08320	COG0196	riboflavin kinase activity
AS891_RS08325	COG1473	amidohydrolase
AS891_RS08330	COG0730	response to heat
AS891_RS08340	COG4109	DRTGG domain
AS891_RS08350	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AS891_RS08370	COG0587	DNA-directed DNA polymerase activity
AS891_RS08375	COG0281	malic enzyme
AS891_RS08380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AS891_RS08385	COG0825	malonyl-CoA metabolic process
AS891_RS08390	COG0205	6-phosphofructokinase activity
AS891_RS08395	COG0469	pyruvate kinase activity
AS891_RS08400	COG3030	protein affecting phage T7 exclusion by the F plasmid
AS891_RS08405	COG0628	permease
AS891_RS08410	COG2707	UPF0756 membrane protein
AS891_RS08415	COG0372	Belongs to the citrate synthase family
AS891_RS08420	COG0538	isocitrate dehydrogenase activity
AS891_RS08425	COG0039	L-malate dehydrogenase activity
AS891_RS08430	COG0745	RESPONSE REGULATOR receiver
AS891_RS08435	COG5002	protein histidine kinase activity
AS891_RS08440	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS891_RS08440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS891_RS08445	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS891_RS08460	COG0237	dephospho-CoA kinase activity
AS891_RS08465	COG0656	L-ascorbic acid biosynthetic process
AS891_RS08470	COG2814	Major facilitator Superfamily
AS891_RS08475	COG1733	regulation of RNA biosynthetic process
AS891_RS08480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AS891_RS08485	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AS891_RS08490	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AS891_RS08495	COG3611	Membrane attachment protein
AS891_RS08500	COG1484	DNA-dependent DNA replication
AS891_RS08505	COG0398	Pfam SNARE associated Golgi protein
AS891_RS08515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AS891_RS08520	COG1011	Hydrolase
AS891_RS08525	COG3275	phosphorelay sensor kinase activity
AS891_RS08530	COG3279	Response regulator of the LytR AlgR family
AS891_RS08535	COG1380	Effector of murein hydrolase LrgA
AS891_RS08540	COG1346	cytolysis
AS891_RS08550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AS891_RS08555	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AS891_RS08560	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AS891_RS08565	COG3326	Membrane
AS891_RS08575	COG1363	Peptidase, m42
AS891_RS08580	COG3507	Belongs to the glycosyl hydrolase 43 family
AS891_RS08585	COG2160	L-arabinose isomerase activity
AS891_RS08590	COG1069	ribulokinase activity
AS891_RS08595	COG0235	Class ii aldolase
AS891_RS08600	COG0647	UMP catabolic process
AS891_RS08605	COG0371	Dehydrogenase
AS891_RS08610	COG1653	transport
AS891_RS08615	COG1175	transmembrane transport
AS891_RS08620	COG0395	ABC-type sugar transport system, permease component
AS891_RS08625	COG3534	alpha-L-arabinofuranosidase
AS891_RS08630	COG1966	Carbon starvation protein
AS891_RS08640	COG0346	lactoylglutathione lyase activity
AS891_RS08645	COG0247	lactate metabolic process
AS891_RS08650	COG0277	FAD linked oxidase domain protein
AS891_RS08655	COG3835	regulator
AS891_RS08665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS891_RS08675	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AS891_RS08680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS891_RS08680	COG0072	phenylalanine-tRNA ligase activity
AS891_RS08685	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AS891_RS08690	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AS891_RS08695	COG1286	toxin biosynthetic process
AS891_RS08700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS891_RS08700	COG1796	DNA polymerase
AS891_RS08705	COG1193	negative regulation of DNA recombination
AS891_RS08710	COG3766	membrane
AS891_RS08715	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_RS08720	COG1309	transcriptional regulator
AS891_RS08725	COG1024	Enoyl-CoA hydratase
AS891_RS08730	COG2086	electron transfer activity
AS891_RS08735	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AS891_RS08740	COG3534	alpha-L-arabinofuranosidase
AS891_RS08745	COG3118	belongs to the thioredoxin family
AS891_RS08750	COG0322	excinuclease ABC activity
AS891_RS08755	COG0527	aspartate kinase activity
AS891_RS08760	COG1719	4-vinyl reductase, 4VR
AS891_RS08770	COG2009	succinate dehydrogenase
AS891_RS08775	COG1053	succinate dehydrogenase
AS891_RS08780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AS891_RS08785	COG0824	Thioesterase
AS891_RS08790	COG2197	response regulator
AS891_RS08795	COG1846	Transcriptional regulator
AS891_RS08800	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AS891_RS08805	COG5401	PFAM Sporulation and spore germination
AS891_RS08810	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AS891_RS08815	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AS891_RS08820	COG0622	Phosphoesterase
AS891_RS08830	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AS891_RS08840	COG0454	-acetyltransferase
AS891_RS08850	COG0028	Belongs to the TPP enzyme family
AS891_RS08855	COG0440	acetolactate synthase activity
AS891_RS08860	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AS891_RS08865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS891_RS08870	COG0473	3-isopropylmalate dehydrogenase activity
AS891_RS08875	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AS891_RS08880	COG0066	3-isopropylmalate dehydratase activity
AS891_RS08885	COG0457	Tetratricopeptide repeat
AS891_RS08885	COG1477	protein flavinylation
AS891_RS08890	COG0544	peptidyl-prolyl cis-trans isomerase activity
AS891_RS08895	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AS891_RS08900	COG1067	ATP-dependent peptidase activity
AS891_RS08900	COG0470	DNA polymerase III
AS891_RS08905	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AS891_RS08910	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AS891_RS08920	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AS891_RS08925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS891_RS08930	COG0181	hydroxymethylbilane synthase activity
AS891_RS08935	COG1587	Uroporphyrinogen-III synthase
AS891_RS08940	COG0113	porphobilinogen synthase activity
AS891_RS08945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AS891_RS08950	COG1388	LysM domain
AS891_RS08955	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS891_RS08965	COG0525	valine-tRNA ligase activity
AS891_RS08970	COG0285	dihydrofolate synthase activity
AS891_RS08975	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AS891_RS08985	COG0424	maF-like protein
AS891_RS08990	COG2003	Belongs to the UPF0758 family
AS891_RS08995	COG1077	Cell shape determining protein MreB Mrl
AS891_RS09005	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AS891_RS09010	COG0850	regulation of cytokinetic process
AS891_RS09015	COG2894	cell division
AS891_RS09020	COG0739	heme binding
AS891_RS09025	COG1994	Peptidase M50
AS891_RS09030	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AS891_RS09035	COG2868	ribosomal protein
AS891_RS09040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AS891_RS09050	COG3290	protein histidine kinase activity
AS891_RS09055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AS891_RS09060	COG4492	Belongs to the UPF0735 family
AS891_RS09065	COG0077	Prephenate dehydratase
AS891_RS09070	COG1827	regulation of RNA biosynthetic process
AS891_RS09075	COG1104	cysteine desulfurase activity
AS891_RS09080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AS891_RS09085	COG0157	Belongs to the NadC ModD family
AS891_RS09090	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AS891_RS09095	COG1388	LysM domain
AS891_RS09105	COG0217	transcriptional regulatory protein
AS891_RS09110	COG1115	amino acid carrier protein
AS891_RS09130	COG2112	serine threonine protein kinase
AS891_RS09135	COG0673	inositol 2-dehydrogenase activity
AS891_RS09140	COG2814	Major facilitator Superfamily
AS891_RS09150	COG0632	four-way junction helicase activity
AS891_RS09155	COG2255	four-way junction helicase activity
AS891_RS09165	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AS891_RS09170	COG0343	queuine tRNA-ribosyltransferase activity
AS891_RS09175	COG1862	Preprotein translocase
AS891_RS09185	COG2323	membrane
AS891_RS09190	COG2244	polysaccharide biosynthetic process
AS891_RS09200	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS891_RS09200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS891_RS09205	COG0490	domain, Protein
AS891_RS09210	COG5416	Lipopolysaccharide assembly protein A domain
AS891_RS09215	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AS891_RS09215	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AS891_RS09220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS891_RS09225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AS891_RS09230	COG1490	D-aminoacyl-tRNA deacylase activity
AS891_RS09235	COG3103	Sh3 type 3 domain protein
AS891_RS09235	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS891_RS09235	COG4991	sh3 domain protein
AS891_RS09245	COG0124	histidyl-tRNA synthetase
AS891_RS09250	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AS891_RS09260	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AS891_RS09265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AS891_RS09270	COG1959	2 iron, 2 sulfur cluster binding
AS891_RS09275	COG1104	cysteine desulfurase activity
AS891_RS09280	COG0482	sulfurtransferase activity
AS891_RS09285	COG0457	Tetratricopeptide repeat
AS891_RS09290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AS891_RS09295	COG3881	PFAM PRC-barrel domain
AS891_RS09310	COG0765	amino acid transport
AS891_RS09315	COG0765	amino acid transport
AS891_RS09320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_RS09325	COG1126	abc transporter atp-binding protein
AS891_RS09330	COG0628	permease
AS891_RS09335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AS891_RS09340	COG4472	Bacterial protein of unknown function (DUF965)
AS891_RS09345	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AS891_RS09350	COG3906	Belongs to the UPF0473 family
AS891_RS09355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AS891_RS09360	COG4122	O-methyltransferase activity
AS891_RS09365	COG0826	peptidase U32
AS891_RS09370	COG0826	peptidase U32
AS891_RS09375	COG0572	uridine kinase
AS891_RS09380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AS891_RS09385	COG0768	penicillin binding
AS891_RS09400	COG2226	methyltransferase
AS891_RS09405	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AS891_RS09410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS891_RS09415	COG0626	cystathionine gamma-synthase activity
AS891_RS09425	COG2427	Protein of unknown function (DUF1641)
AS891_RS09430	COG3383	formate dehydrogenase (NAD+) activity
AS891_RS09435	COG5609	conserved protein (DUF2294)
AS891_RS09440	COG2116	formate transmembrane transporter activity
AS891_RS09450	COG2226	methyltransferase
AS891_RS09455	COG1309	transcriptional regulator
AS891_RS09460	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AS891_RS09460	COG2124	cytochrome p450
AS891_RS09470	COG2755	lipolytic protein G-D-S-L family
AS891_RS09470	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AS891_RS09480	COG1595	DNA-templated transcription, initiation
AS891_RS09485	COG1378	Sugar-specific transcriptional regulator TrmB
AS891_RS09490	COG1280	lysine exporter protein (LysE YggA)
AS891_RS09495	COG1113	amino acid transport
AS891_RS09500	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AS891_RS09500	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AS891_RS09505	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_RS09510	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_RS09515	COG3715	PTS system
AS891_RS09520	COG3716	PTS system mannose fructose sorbose family IID component
AS891_RS09525	COG1621	beta-fructofuranosidase activity
AS891_RS09530	COG0693	protein deglycase activity
AS891_RS09535	COG1064	alcohol dehydrogenase
AS891_RS09545	COG0789	Transcriptional regulator
AS891_RS09550	COG5577	PFAM Coat F domain
AS891_RS09560	COG1063	alcohol dehydrogenase
AS891_RS09565	COG5577	PFAM Coat F domain
AS891_RS09575	COG0346	lactoylglutathione lyase activity
AS891_RS09580	COG4991	sh3 domain protein
AS891_RS09585	COG4991	sh3 domain protein
AS891_RS09590	COG0596	Alpha beta hydrolase
AS891_RS09595	COG5566	PFAM Mor transcription activator
AS891_RS09600	COG3409	Peptidoglycan-binding domain 1 protein
AS891_RS09605	COG2828	Protein conserved in bacteria
AS891_RS09610	COG0583	DNA-binding transcription factor activity
AS891_RS09615	COG2851	Citrate transporter
AS891_RS09620	COG0667	Aldo Keto reductase
AS891_RS09625	COG1595	DNA-templated transcription, initiation
AS891_RS09630	COG3443	Belongs to the bacterial solute-binding protein 9 family
AS891_RS09645	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AS891_RS09655	COG2070	2-Nitropropane dioxygenase
AS891_RS09665	COG2318	DinB family
AS891_RS09675	COG1335	isochorismatase
AS891_RS09685	COG2124	cytochrome p450
AS891_RS09690	COG2732	(Barnase) inhibitor
AS891_RS09695	COG1522	sequence-specific DNA binding
AS891_RS09700	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AS891_RS09705	COG1687	branched-chain amino acid
AS891_RS09710	COG1114	Component of the transport system for branched-chain amino acids
AS891_RS09720	COG0583	DNA-binding transcription factor activity
AS891_RS09725	COG1942	4-Oxalocrotonate Tautomerase
AS891_RS09730	COG1230	cation diffusion facilitator family transporter
AS891_RS09735	COG2072	flavoprotein involved in K transport
AS891_RS09740	COG0583	DNA-binding transcription factor activity
AS891_RS09745	COG0697	spore germination
AS891_RS09755	COG1253	flavin adenine dinucleotide binding
AS891_RS09760	COG0456	acetyltransferase
AS891_RS09765	COG2814	Major facilitator Superfamily
AS891_RS09770	COG4978	Transcriptional regulator
AS891_RS09770	COG0789	Transcriptional regulator
AS891_RS09785	COG0662	Cupin 2, conserved barrel domain protein
AS891_RS09790	COG1937	Protein conserved in bacteria
AS891_RS09795	COG2210	Belongs to the sulfur carrier protein TusA family
AS891_RS09800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS891_RS09800	COG0425	Belongs to the sulfur carrier protein TusA family
AS891_RS09810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_RS09810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS891_RS09815	COG0425	Belongs to the sulfur carrier protein TusA family
AS891_RS09820	COG0730	response to heat
AS891_RS09830	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS891_RS09835	COG0454	-acetyltransferase
AS891_RS09845	COG2311	Membrane
AS891_RS09850	COG0745	RESPONSE REGULATOR receiver
AS891_RS09855	COG5002	protein histidine kinase activity
AS891_RS09855	COG0642	Histidine kinase
AS891_RS09860	COG3223	Belongs to the PsiE family
AS891_RS09875	COG2856	Zn peptidase
AS891_RS09880	COG0563	adenylate kinase activity
AS891_RS09890	COG3620	sequence-specific DNA binding
AS891_RS09895	COG1476	TRANSCRIPTIONal
AS891_RS09920	COG5377	YqaJ viral recombinase family
AS891_RS09925	COG3723	Recombinational DNA repair protein, rece pathway
AS891_RS09930	COG3935	DnaD domain protein
AS891_RS09935	COG1484	DNA-dependent DNA replication
AS891_RS09950	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AS891_RS09965	COG3677	Transposase
AS891_RS09975	COG5484	DNA packaging
AS891_RS09980	COG1783	phage Terminase large subunit
AS891_RS09985	COG5518	Phage portal protein
AS891_RS09990	COG2369	cell adhesion
AS891_RS10000	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AS891_RS10005	COG4653	Phage capsid family
AS891_RS10065	COG5280	Phage tail tape measure protein TP901
AS891_RS10065	COG3953	SLT domain
AS891_RS10070	COG1652	LysM domain
AS891_RS10075	COG4193	domain, Protein
AS891_RS10085	COG3628	GPW Gp25 family protein
AS891_RS10090	COG3299	homolog of phage Mu protein gp47
AS891_RS10095	COG3778	Protein conserved in bacteria
AS891_RS10125	COG4824	toxin secretion phage lysis holin
AS891_RS10130	COG3409	Peptidoglycan-binding domain 1 protein
AS891_RS10130	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS891_RS10155	COG5444	nuclease activity
AS891_RS10170	COG0457	Tetratricopeptide repeat
AS891_RS10175	COG3403	YqcI/YcgG family
AS891_RS10180	COG0640	Transcriptional regulator
AS891_RS10185	COG0346	lactoylglutathione lyase activity
AS891_RS10190	COG0798	PFAM Bile acid sodium symporter
AS891_RS10195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS891_RS10200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS891_RS10210	COG3209	COG3209 Rhs family protein
AS891_RS10220	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AS891_RS10225	COG0398	Pfam SNARE associated Golgi protein
AS891_RS10230	COG3409	Peptidoglycan-binding domain 1 protein
AS891_RS10230	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS891_RS10235	COG2755	lipolytic protein G-D-S-L family
AS891_RS10250	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AS891_RS10255	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AS891_RS10260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AS891_RS10265	COG1534	Rna-binding protein
AS891_RS10270	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AS891_RS10275	COG1713	HD superfamily hydrolase involved in NAD metabolism
AS891_RS10280	COG0799	negative regulation of ribosome biogenesis
AS891_RS10285	COG2226	methyltransferase
AS891_RS10290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS891_RS10295	COG1596	polysaccharide export
AS891_RS10295	COG1555	photosystem II stabilization
AS891_RS10300	COG2131	deaminase
AS891_RS10305	COG0658	competence protein
AS891_RS10305	COG2333	competence protein COMEC
AS891_RS10315	COG1466	dna polymerase III delta subunit
AS891_RS10320	COG0268	Binds directly to 16S ribosomal RNA
AS891_RS10325	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AS891_RS10330	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS891_RS10340	COG0481	GTPase activity
AS891_RS10345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS891_RS10350	COG1420	regulation of RNA biosynthetic process
AS891_RS10355	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AS891_RS10360	COG0443	Heat shock 70 kDa protein
AS891_RS10365	COG0484	heat shock protein binding
AS891_RS10370	COG2264	protein methyltransferase activity
AS891_RS10375	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AS891_RS10380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS891_RS10385	COG1283	sodium-dependent phosphate transmembrane transporter activity
AS891_RS10395	COG1610	YqeY-like protein
AS891_RS10400	COG1030	water channel activity
AS891_RS10405	COG4864	UPF0365 protein
AS891_RS10420	COG0561	phosphatase activity
AS891_RS10425	COG1702	phosphate starvation-inducible protein PhoH
AS891_RS10435	COG1480	7TM receptor with intracellular HD hydrolase
AS891_RS10440	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AS891_RS10445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AS891_RS10450	COG0295	cytidine deaminase activity
AS891_RS10455	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AS891_RS10465	COG1381	Involved in DNA repair and RecF pathway recombination
AS891_RS10470	COG0752	glycyl-tRNA synthetase alpha subunit
AS891_RS10475	COG0751	glycine-tRNA ligase activity
AS891_RS10480	COG0517	IMP dehydrogenase activity
AS891_RS10485	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AS891_RS10490	COG1671	Belongs to the UPF0178 family
AS891_RS10495	COG0358	DNA primase activity
AS891_RS10500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AS891_RS10505	COG2010	Cytochrome c
AS891_RS10510	COG2384	SAM-dependent methyltransferase
AS891_RS10515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AS891_RS10520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AS891_RS10530	COG0513	Belongs to the DEAD box helicase family
AS891_RS10535	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AS891_RS10545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_RS10550	COG0735	belongs to the Fur family
AS891_RS10555	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AS891_RS10560	COG4709	membrane
AS891_RS10565	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AS891_RS10570	COG1388	LysM domain
AS891_RS10580	COG5521	maltodextrose utilization protein MalA
AS891_RS10585	COG2839	Protein conserved in bacteria
AS891_RS10590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AS891_RS10595	COG0477	Major facilitator Superfamily
AS891_RS10600	COG0768	penicillin binding
AS891_RS10605	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AS891_RS10610	COG0573	inorganic phosphate transmembrane transporter activity
AS891_RS10615	COG0581	inorganic phosphate transmembrane transporter activity
AS891_RS10620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS891_RS10625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS891_RS10630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AS891_RS10645	COG0438	transferase activity, transferring glycosyl groups
AS891_RS10655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AS891_RS10665	COG0705	Rhomboid family
AS891_RS10665	COG0457	Tetratricopeptide repeat
AS891_RS10670	COG4483	Protein conserved in bacteria
AS891_RS10675	COG1940	carbohydrate kinase activity
AS891_RS10680	COG1368	sulfuric ester hydrolase activity
AS891_RS10685	COG2866	Carboxypeptidase
AS891_RS10695	COG0011	TIGRFAM Protein of
AS891_RS10705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_RS10715	COG1393	Belongs to the ArsC family
AS891_RS10725	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_RS10730	COG1253	flavin adenine dinucleotide binding
AS891_RS10735	COG0598	Magnesium transport protein CorA
AS891_RS10745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AS891_RS10750	COG1459	type II secretion system
AS891_RS10755	COG4537	Required for transformation and DNA binding
AS891_RS10760	COG4970	Tfp pilus assembly protein FimT
AS891_RS10770	COG4940	Competence protein ComGF
AS891_RS10795	COG0681	Belongs to the peptidase S26 family
AS891_RS10805	COG1396	sequence-specific DNA binding
AS891_RS10820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS891_RS10825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AS891_RS10830	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS891_RS10835	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS891_RS10840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS891_RS10845	COG0095	Lipoate-protein ligase
AS891_RS10850	COG1321	iron dependent repressor
AS891_RS10855	COG1752	Esterase of the alpha-beta hydrolase superfamily
AS891_RS10865	COG3872	metal-dependent enzyme
AS891_RS10875	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AS891_RS10880	COG0006	proline dipeptidase activity
AS891_RS10885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AS891_RS10895	COG3854	ATPases associated with a variety of cellular activities
AS891_RS10935	COG0511	ligase activity, forming carbon-carbon bonds
AS891_RS10940	COG0439	Biotin carboxylase
AS891_RS10945	COG1302	Protein conserved in bacteria
AS891_RS10950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AS891_RS10955	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AS891_RS10960	COG1570	exodeoxyribonuclease VII activity
AS891_RS10965	COG1722	exodeoxyribonuclease VII activity
AS891_RS10970	COG0142	geranyltranstransferase activity
AS891_RS10975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AS891_RS10980	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AS891_RS10985	COG1438	arginine binding
AS891_RS10990	COG0497	DNA recombination
AS891_RS10995	COG0750	zinc metalloprotease
AS891_RS11005	COG0745	RESPONSE REGULATOR receiver
AS891_RS11015	COG1902	pentaerythritol trinitrate reductase activity
AS891_RS11030	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS891_RS11035	COG0584	glycerophosphoryl diester phosphodiesterase
AS891_RS11040	COG0183	Belongs to the thiolase family
AS891_RS11045	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS891_RS11050	COG1960	acyl-CoA dehydrogenase activity
AS891_RS11055	COG0372	Belongs to the citrate synthase family
AS891_RS11060	COG2079	MmgE PrpD family protein
AS891_RS11065	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AS891_RS11075	COG3829	transcription factor binding
AS891_RS11075	COG3290	protein histidine kinase activity
AS891_RS11080	COG0280	phosphate acetyltransferase
AS891_RS11085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS891_RS11090	COG3426	butyrate kinase activity
AS891_RS11095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS891_RS11100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS891_RS11105	COG0022	dehydrogenase e1 component
AS891_RS11110	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS891_RS11115	COG4978	Transcriptional regulator
AS891_RS11115	COG0789	Transcriptional regulator
AS891_RS11120	COG2814	Major facilitator Superfamily
AS891_RS11125	COG1597	lipid kinase activity
AS891_RS11135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_RS11140	COG0765	amino acid transport
AS891_RS11145	COG1126	abc transporter atp-binding protein
AS891_RS11150	COG4129	membrane
AS891_RS11155	COG1376	ErfK ybiS ycfS ynhG family protein
AS891_RS11165	COG0346	lactoylglutathione lyase activity
AS891_RS11170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS891_RS11175	COG2195	Cleaves the N-terminal amino acid of tripeptides
AS891_RS11180	COG3361	conserved protein (COG2071)
AS891_RS11185	COG0706	membrane insertase activity
AS891_RS11195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS891_RS11200	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AS891_RS11205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AS891_RS11210	COG1234	tRNA 3'-trailer cleavage
AS891_RS11215	COG0596	Alpha beta hydrolase
AS891_RS11220	COG1902	pentaerythritol trinitrate reductase activity
AS891_RS11225	COG4187	Peptidase family M20/M25/M40
AS891_RS11230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS891_RS11235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_RS11240	COG0300	oxidoreductase activity
AS891_RS11245	COG3048	D-serine ammonia-lyase activity
AS891_RS11250	COG1072	(Pantothenic acid kinase))
AS891_RS11255	COG0346	lactoylglutathione lyase activity
AS891_RS11265	COG2211	Major facilitator Superfamily
AS891_RS11275	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS891_RS11285	COG0456	acetyltransferase
AS891_RS11290	COG2329	Antibiotic biosynthesis monooxygenase
AS891_RS11295	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AS891_RS11295	COG0456	acetyltransferase
AS891_RS11300	COG4918	Iron-sulphur cluster biosynthesis
AS891_RS11310	COG1073	alpha beta
AS891_RS11320	COG0667	Aldo Keto reductase
AS891_RS11330	COG0494	nUDIX hydrolase
AS891_RS11335	COG1379	DNA repair
AS891_RS11340	COG1396	sequence-specific DNA binding
AS891_RS11345	COG0252	asparaginase activity
AS891_RS11350	COG1027	Aspartate ammonia-lyase
AS891_RS11355	COG1757	Na H antiporter
AS891_RS11360	COG0281	malic enzyme
AS891_RS11370	COG1300	Membrane
AS891_RS11375	COG0735	belongs to the Fur family
AS891_RS11385	COG4974	Belongs to the 'phage' integrase family
AS891_RS11390	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AS891_RS11395	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AS891_RS11400	COG1686	Belongs to the peptidase S11 family
AS891_RS11405	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_RS11410	COG2172	sigma factor antagonist activity
AS891_RS11415	COG1191	sigma factor activity
AS891_RS11435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS891_RS11450	COG0697	spore germination
AS891_RS11455	COG0019	diaminopimelate decarboxylase activity
AS891_RS11460	COG4086	secreted protein
AS891_RS11465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AS891_RS11490	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AS891_RS11495	COG0681	Belongs to the peptidase S26 family
AS891_RS11505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS891_RS11505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS891_RS11510	COG0307	riboflavin synthase, alpha
AS891_RS11515	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AS891_RS11515	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AS891_RS11520	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AS891_RS11525	COG0456	acetyltransferase
AS891_RS11530	COG1547	Domain of unknown function (DUF309)
AS891_RS11535	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AS891_RS11540	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AS891_RS11550	COG1686	Belongs to the peptidase S11 family
AS891_RS11555	COG2715	membrane protein required for spore maturation
AS891_RS11560	COG0700	Nucleoside recognition
AS891_RS11565	COG1187	pseudouridine synthase activity
AS891_RS11570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_RS11575	COG1333	cytochrome c biogenesis protein
AS891_RS11580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS891_RS11585	COG0745	RESPONSE REGULATOR receiver
AS891_RS11590	COG5002	protein histidine kinase activity
AS891_RS11595	COG1595	DNA-templated transcription, initiation
AS891_RS11605	COG0710	3-dehydroquinate dehydratase activity
AS891_RS11610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS891_RS11615	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AS891_RS11620	COG1141	Ferredoxin
AS891_RS11625	COG4955	Helix-turn-helix domain
AS891_RS11630	COG0514	ATP-dependent DNA helicase (RecQ)
AS891_RS11635	COG1266	CAAX protease self-immunity
AS891_RS11640	COG1388	LysM domain
AS891_RS11650	COG1408	metallophosphoesterase
AS891_RS11655	COG4862	establishment of competence for transformation
AS891_RS11660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS891_RS11665	COG0492	ferredoxin-NADP+ reductase activity
AS891_RS11670	COG2339	peptidase activity
AS891_RS11675	COG3409	Peptidoglycan-binding domain 1 protein
AS891_RS11675	COG3773	Cell wall hydrolase
AS891_RS11680	COG2959	enzyme of heme biosynthesis
AS891_RS11685	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AS891_RS11695	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AS891_RS11700	COG0539	negative regulation of cytoplasmic translation
AS891_RS11705	COG1304	FMN binding
AS891_RS11730	COG1160	GTP binding
AS891_RS11735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AS891_RS11750	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS891_RS11755	COG0776	regulation of translation
AS891_RS11760	COG0302	gtp cyclohydrolase
AS891_RS11770	COG0142	geranyltranstransferase activity
AS891_RS11775	COG2226	methyltransferase
AS891_RS11780	COG0142	geranyltranstransferase activity
AS891_RS11785	COG0105	UTP biosynthetic process
AS891_RS11795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AS891_RS11800	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AS891_RS11805	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AS891_RS11810	COG4401	Chorismate mutase type I
AS891_RS11815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS891_RS11820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AS891_RS11830	COG0135	phosphoribosylanthranilate isomerase activity
AS891_RS11835	COG0133	tryptophan synthase activity
AS891_RS11840	COG0159	tryptophan synthase activity
AS891_RS11845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS891_RS11850	COG0287	Prephenate dehydrogenase
AS891_RS11855	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AS891_RS11860	COG0457	Tetratricopeptide repeat
AS891_RS11865	COG5582	Belongs to the UPF0302 family
AS891_RS11875	COG0723	plastoquinol--plastocyanin reductase activity
AS891_RS11880	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS891_RS11885	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS891_RS11885	COG2010	Cytochrome c
AS891_RS11890	COG4347	Protein of unknown function (DUF1405)
AS891_RS11900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_RS11905	COG1694	Mazg nucleotide pyrophosphohydrolase
AS891_RS11910	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AS891_RS11915	COG1803	Methylglyoxal synthase
AS891_RS11920	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS891_RS11925	COG0438	transferase activity, transferring glycosyl groups
AS891_RS11930	COG0617	tRNA 3'-terminal CCA addition
AS891_RS11935	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AS891_RS11935	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AS891_RS11940	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AS891_RS11945	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AS891_RS11950	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AS891_RS11955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AS891_RS11955	COG1199	ATP-dependent helicase activity
AS891_RS11965	COG5353	protein conserved in bacteria
AS891_RS11970	COG0436	Aminotransferase
AS891_RS11975	COG0017	Asparaginyl-tRNA synthetase
AS891_RS11980	COG3935	DnaD domain protein
AS891_RS11985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AS891_RS11995	COG4499	WXG100 protein secretion system (Wss), protein YukC
AS891_RS11995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS891_RS12000	COG3331	DNA recombination
AS891_RS12035	COG0071	Belongs to the small heat shock protein (HSP20) family
AS891_RS12040	COG2190	(PTS) system
AS891_RS12045	COG1111	helicase
AS891_RS12045	COG1205	dead DEAH box helicase
AS891_RS12050	COG3359	exonuclease
AS891_RS12060	COG4474	Belongs to the UPF0398 family
AS891_RS12075	COG0116	Belongs to the methyltransferase superfamily
AS891_RS12085	COG1199	ATP-dependent helicase activity
AS891_RS12090	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS12095	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AS891_RS12100	COG1609	Transcriptional regulator
AS891_RS12105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS891_RS12110	COG0800	Aldolase
AS891_RS12120	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AS891_RS12125	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS891_RS12130	COG2233	PERMEase
AS891_RS12135	COG3424	synthase
AS891_RS12140	COG1755	Isoprenylcysteine carboxyl methyltransferase
AS891_RS12145	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS891_RS12165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS891_RS12175	COG0328	RNA-DNA hybrid ribonuclease activity
AS891_RS12180	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AS891_RS12185	COG0328	RNA-DNA hybrid ribonuclease activity
AS891_RS12205	COG1278	Cold shock
AS891_RS12210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS891_RS12215	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AS891_RS12220	COG0386	Belongs to the glutathione peroxidase family
AS891_RS12225	COG1418	mRNA catabolic process
AS891_RS12230	COG1413	lyase activity
AS891_RS12235	COG0129	dihydroxy-acid dehydratase activity
AS891_RS12245	COG2521	methyltransferase
AS891_RS12245	COG2136	Putative SAM-dependent methyltransferase
AS891_RS12255	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AS891_RS12260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AS891_RS12265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS891_RS12270	COG0204	Acyl-transferase
AS891_RS12275	COG1272	protein, Hemolysin III
AS891_RS12280	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AS891_RS12285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AS891_RS12300	COG1999	signal sequence binding
AS891_RS12305	COG2755	lipolytic protein G-D-S-L family
AS891_RS12310	COG4698	Protein conserved in bacteria
AS891_RS12320	COG0534	Mate efflux family protein
AS891_RS12325	COG1846	Transcriptional regulator
AS891_RS12330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS891_RS12335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS891_RS12340	COG1086	Polysaccharide biosynthesis protein
AS891_RS12345	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS891_RS12370	COG2746	aminoglycoside 3-N-acetyltransferase activity
AS891_RS12380	COG1525	nuclease
AS891_RS12390	COG4282	regulation of fungal-type cell wall biogenesis
AS891_RS12395	COG5444	nuclease activity
AS891_RS12410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_RS12440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS891_RS12455	COG3271	cysteine-type peptidase activity
AS891_RS12455	COG2274	protein secretion by the type I secretion system
AS891_RS12460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_RS12465	COG0463	Glycosyl transferase, family 2
AS891_RS12470	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AS891_RS12485	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS891_RS12500	COG4632	Exopolysaccharide biosynthesis protein
AS891_RS12500	COG5434	Belongs to the glycosyl hydrolase 28 family
AS891_RS12510	COG2433	Pfam Transposase IS66
AS891_RS12520	COG0741	lytic transglycosylase activity
AS891_RS12520	COG1196	nuclear chromosome segregation
AS891_RS12520	COG0739	heme binding
AS891_RS12550	COG0582	viral genome integration into host DNA
AS891_RS12650	COG4373	Mu-like prophage FluMu protein gp28
AS891_RS12680	COG0776	regulation of translation
AS891_RS12695	COG1395	domain, Protein
AS891_RS12730	COG3655	Transcriptional regulator
AS891_RS12810	COG0582	viral genome integration into host DNA
AS891_RS12825	COG3655	Transcriptional regulator
AS891_RS12880	COG3646	Phage regulatory protein
AS891_RS12880	COG3645	SOS response
AS891_RS12900	COG1388	LysM domain
AS891_RS12910	COG4474	Belongs to the UPF0398 family
AS891_RS12965	COG1793	dna ligase
AS891_RS12970	COG2135	peptidase activity
AS891_RS12985	COG4195	phage-related replication protein
AS891_RS12990	COG5434	Belongs to the glycosyl hydrolase 28 family
AS891_RS12990	COG3420	alginic acid biosynthetic process
AS891_RS13020	COG2887	Belongs to the helicase family. UvrD subfamily
AS891_RS13030	COG0305	Participates in initiation and elongation during chromosome replication
AS891_RS13035	COG0358	DNA primase activity
AS891_RS13040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AS891_RS13045	COG0587	DNA-directed DNA polymerase activity
AS891_RS13050	COG3584	3D domain protein
AS891_RS13075	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AS891_RS13080	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AS891_RS13090	COG0270	DNA (cytosine-5-)-methyltransferase activity
AS891_RS13180	COG1780	Probably involved in ribonucleotide reductase function
AS891_RS13185	COG1372	Participates in initiation and elongation during chromosome replication
AS891_RS13185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS891_RS13190	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS891_RS13190	COG1372	Participates in initiation and elongation during chromosome replication
AS891_RS13200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS891_RS13215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_RS13220	COG0756	dUTP diphosphatase activity
AS891_RS13225	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AS891_RS13260	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS891_RS13310	COG3331	DNA recombination
AS891_RS13320	COG1086	Polysaccharide biosynthesis protein
AS891_RS13325	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
AS891_RS13330	COG4641	Protein conserved in bacteria
AS891_RS13345	COG0463	Glycosyl transferase, family 2
AS891_RS13350	COG0456	acetyltransferase
AS891_RS13365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS891_RS13370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AS891_RS13375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AS891_RS13380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS891_RS13385	COG0456	acetyltransferase
AS891_RS13390	COG1509	lysine 2,3-aminomutase activity
AS891_RS13400	COG4479	Belongs to the UPF0346 family
AS891_RS13425	COG0671	phosphoesterase, PA-phosphatase related
AS891_RS13440	COG0813	purine-nucleoside phosphorylase activity
AS891_RS13445	COG1876	peptidase activity
AS891_RS13455	COG2226	methyltransferase
AS891_RS13460	COG3409	Peptidoglycan-binding domain 1 protein
AS891_RS13460	COG0793	Belongs to the peptidase S41A family
AS891_RS13465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS891_RS13475	COG0346	lactoylglutathione lyase activity
AS891_RS13480	COG0400	carboxylic ester hydrolase activity
AS891_RS13485	COG0778	Nitroreductase
AS891_RS13490	COG1733	regulation of RNA biosynthetic process
AS891_RS13495	COG1942	4-Oxalocrotonate Tautomerase
AS891_RS13500	COG2610	gluconate transmembrane transporter activity
AS891_RS13515	COG2962	Rard protein
AS891_RS13525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS891_RS13530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS891_RS13535	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_RS13540	COG0534	Mate efflux family protein
AS891_RS13545	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AS891_RS13550	COG1819	glycosyl
AS891_RS13555	COG1388	LysM domain
AS891_RS13555	COG0791	NLP P60 protein
AS891_RS13560	COG2032	superoxide dismutase activity
AS891_RS13565	COG0714	Associated with various cellular activities
AS891_RS13570	COG4548	von Willebrand factor, type A
AS891_RS13575	COG0567	Dehydrogenase, E1 component
AS891_RS13580	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS891_RS13585	COG0385	Bile acid
AS891_RS13590	COG0733	neurotransmitter:sodium symporter activity
AS891_RS13595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AS891_RS13600	COG1657	PFAM Prenyltransferase squalene oxidase
AS891_RS13605	COG1012	belongs to the aldehyde dehydrogenase family
AS891_RS13630	COG0071	Belongs to the small heat shock protein (HSP20) family
AS891_RS13645	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS891_RS13650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AS891_RS13665	COG0514	ATP-dependent DNA helicase (RecQ)
AS891_RS13670	COG1388	LysM domain
AS891_RS13670	COG3584	3D domain protein
AS891_RS13675	COG2197	response regulator
AS891_RS13680	COG4585	Histidine kinase
AS891_RS13685	COG3239	Fatty acid desaturase
AS891_RS13690	COG1619	proteins homologs of microcin C7 resistance protein MccF
AS891_RS13705	COG2322	membrane
AS891_RS13710	COG0741	lytic transglycosylase activity
AS891_RS13715	COG0640	Transcriptional regulator
AS891_RS13725	COG2378	regulation of single-species biofilm formation
AS891_RS13730	COG3708	Transcriptional regulator
AS891_RS13735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_RS13740	COG1309	transcriptional regulator
AS891_RS13745	COG0456	acetyltransferase
AS891_RS13750	COG0662	Cupin 2, conserved barrel domain protein
AS891_RS13750	COG2207	Transcriptional regulator
AS891_RS13755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS891_RS13760	COG5434	Belongs to the glycosyl hydrolase 28 family
AS891_RS13765	COG1231	oxidoreductase activity
AS891_RS13770	COG4282	regulation of fungal-type cell wall biogenesis
AS891_RS13775	COG5444	nuclease activity
AS891_RS13795	COG5290	Psort location Cytoplasmic, score
AS891_RS13810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS891_RS13815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS891_RS13825	COG0457	Tetratricopeptide repeat
AS891_RS13855	COG1793	dna ligase
AS891_RS13860	COG2135	peptidase activity
AS891_RS13875	COG1396	sequence-specific DNA binding
AS891_RS13880	COG2314	TM2 domain
AS891_RS13885	COG0726	polysaccharide deacetylase
AS891_RS13890	COG3848	Pyruvate phosphate dikinase
AS891_RS13890	COG0574	Belongs to the PEP-utilizing enzyme family
AS891_RS13910	COG2367	Beta-lactamase
AS891_RS13915	COG0693	protein deglycase activity
AS891_RS13925	COG0697	spore germination
AS891_RS13930	COG0583	DNA-binding transcription factor activity
AS891_RS13935	COG3739	integral membrane protein
AS891_RS13940	COG3655	Transcriptional regulator
AS891_RS13950	COG2720	vancomycin resistance protein
AS891_RS13965	COG0456	acetyltransferase
AS891_RS13975	COG2140	Oxalate decarboxylase
AS891_RS13985	COG2135	peptidase activity
AS891_RS13990	COG3866	Pectate lyase
AS891_RS13995	COG3619	membrane
AS891_RS14000	COG4305	rare lipoprotein A
AS891_RS14005	COG2368	4-hydroxyphenylacetate
AS891_RS14010	COG5278	phosphoserine phosphatase activity
AS891_RS14010	COG0840	transmembrane signaling receptor activity
AS891_RS14035	COG0243	molybdopterin cofactor binding
AS891_RS14040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS891_RS14045	COG1070	Carbohydrate kinase
AS891_RS14050	COG2814	Major facilitator Superfamily
AS891_RS14055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_RS14065	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AS891_RS14070	COG0300	oxidoreductase activity
AS891_RS14080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS891_RS14085	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AS891_RS14090	COG0583	DNA-binding transcription factor activity
AS891_RS14095	COG0069	glutamate synthase activity
AS891_RS14095	COG0067	glutamate synthase
AS891_RS14095	COG0070	glutamate synthase
AS891_RS14100	COG0493	'glutamate synthase
AS891_RS14105	COG0604	alcohol dehydrogenase
AS891_RS14110	COG0583	DNA-binding transcription factor activity
AS891_RS14115	COG0405	Gamma-glutamyltransferase
AS891_RS14120	COG0166	Belongs to the GPI family
AS891_RS14125	COG0582	viral genome integration into host DNA
AS891_RS14140	COG0534	Mate efflux family protein
AS891_RS14145	COG2017	converts alpha-aldose to the beta-anomer
AS891_RS14150	COG2027	D-alanyl-D-alanine carboxypeptidase
AS891_RS14155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_RS14160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_RS14165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_RS14170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_RS14175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_RS14180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_RS14180	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AS891_RS14190	COG1649	PFAM Uncharacterised BCR, COG1649
AS891_RS14205	COG1960	acyl-CoA dehydrogenase activity
AS891_RS14210	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_RS14215	COG0439	Biotin carboxylase
AS891_RS14220	COG0511	ligase activity, forming carbon-carbon bonds
AS891_RS14225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS891_RS14230	COG1024	Enoyl-CoA hydratase
AS891_RS14235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS891_RS14240	COG2404	hydrolase activity, acting on ester bonds
AS891_RS14245	COG0586	Pfam SNARE associated Golgi protein
AS891_RS14250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS891_RS14255	COG2246	polysaccharide biosynthetic process
AS891_RS14260	COG3507	Belongs to the glycosyl hydrolase 43 family
AS891_RS14265	COG5520	Belongs to the glycosyl hydrolase 30 family
AS891_RS14275	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AS891_RS14280	COG1115	amino acid carrier protein
AS891_RS14295	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS891_RS14300	COG0187	DNA topoisomerase II activity
AS891_RS14305	COG1832	CoA-binding protein
AS891_RS14310	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AS891_RS14315	COG4841	protein insertion into membrane
AS891_RS14325	COG0824	Thioesterase
AS891_RS14345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_RS14350	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AS891_RS14365	COG0071	Belongs to the small heat shock protein (HSP20) family
AS891_RS14375	COG4846	Membrane protein involved in cytochrome C biogenesis
AS891_RS14380	COG2201	protein-glutamate methylesterase activity
AS891_RS14385	COG0785	Cytochrome C biogenesis protein
AS891_RS14395	COG3763	UPF0154 protein
AS891_RS14405	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AS891_RS14410	COG4224	UPF0291 protein
AS891_RS14415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS891_RS14420	COG1388	LysM domain
AS891_RS14425	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AS891_RS14435	COG0346	lactoylglutathione lyase activity
AS891_RS14445	COG4195	phage-related replication protein
AS891_RS14475	COG0531	amino acid
AS891_RS14480	COG0697	spore germination
AS891_RS14495	COG3832	glyoxalase III activity
AS891_RS14510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS891_RS14535	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AS891_RS14545	COG0756	dUTP diphosphatase activity
AS891_RS14555	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AS891_RS14560	COG2814	Major facilitator Superfamily
AS891_RS14565	COG1525	nuclease
AS891_RS14570	COG1070	Carbohydrate kinase
AS891_RS14575	COG2115	Belongs to the xylose isomerase family
AS891_RS14580	COG1940	carbohydrate kinase activity
AS891_RS14585	COG3507	Belongs to the glycosyl hydrolase 43 family
AS891_RS14590	COG2211	Major facilitator Superfamily
AS891_RS14595	COG0135	phosphoribosylanthranilate isomerase activity
AS891_RS14620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_RS14630	COG4282	regulation of fungal-type cell wall biogenesis
AS891_RS14650	COG0174	glutamine synthetase
AS891_RS14655	COG0789	Transcriptional regulator
AS891_RS14660	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AS891_RS14665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AS891_RS14675	COG0464	growth
AS891_RS14680	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS891_RS14685	COG4112	unkown
AS891_RS14690	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS891_RS14695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS891_RS14700	COG1780	Probably involved in ribonucleotide reductase function
AS891_RS14715	COG1923	regulation of RNA biosynthetic process
AS891_RS14720	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AS891_RS14735	COG2076	Multidrug Resistance protein
AS891_RS14740	COG2076	Multidrug Resistance protein
AS891_RS14745	COG1764	response to oxidative stress
AS891_RS14750	COG4195	phage-related replication protein
AS891_RS14760	COG1404	Belongs to the peptidase S8 family
AS891_RS14765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_RS14775	COG2124	cytochrome p450
AS891_RS14780	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AS891_RS14780	COG3321	synthase
AS891_RS14780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS891_RS14780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS891_RS14785	COG4221	oxidoreductase activity
AS891_RS14785	COG3321	synthase
AS891_RS14785	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS14785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_RS14790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS891_RS14790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS14790	COG3321	synthase
AS891_RS14790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS891_RS14795	COG0300	oxidoreductase activity
AS891_RS14795	COG4221	oxidoreductase activity
AS891_RS14795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS891_RS14795	COG3321	synthase
AS891_RS14800	COG3321	synthase
AS891_RS14800	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_RS14800	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS14800	COG0300	oxidoreductase activity
AS891_RS14800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_RS14805	COG1024	Enoyl-CoA hydratase
AS891_RS14810	COG1024	Enoyl-CoA hydratase
AS891_RS14815	COG3425	synthase
AS891_RS14820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS891_RS14825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS891_RS14835	COG3321	synthase
AS891_RS14840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AS891_RS14850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_RS14855	COG3226	Transcriptional regulator
AS891_RS14875	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AS891_RS14880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AS891_RS14890	COG4550	Control of competence regulator ComK, YlbF/YmcA
AS891_RS14895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS891_RS14900	COG0156	8-amino-7-oxononanoate synthase activity
AS891_RS14905	COG1063	alcohol dehydrogenase
AS891_RS14910	COG2359	stage V sporulation protein S
AS891_RS14915	COG1692	metallophosphoesterase
AS891_RS14920	COG1418	mRNA catabolic process
AS891_RS14925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS891_RS14930	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AS891_RS14935	COG1546	Belongs to the CinA family
AS891_RS14935	COG1058	Belongs to the CinA family
AS891_RS14940	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AS891_RS14945	COG1426	Protein conserved in bacteria
AS891_RS14960	COG0300	oxidoreductase activity
AS891_RS14965	COG0612	Peptidase, M16
AS891_RS14970	COG0612	Peptidase, M16
AS891_RS14975	COG2814	Major facilitator Superfamily
AS891_RS14980	COG2188	Transcriptional regulator
AS891_RS14985	COG4980	gas vesicle protein
AS891_RS14985	COG1674	ftsk spoiiie
AS891_RS14995	COG0740	serine-type endopeptidase activity
AS891_RS15000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS891_RS15005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS891_RS15010	COG0527	aspartate kinase activity
AS891_RS15015	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AS891_RS15020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AS891_RS15025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS891_RS15035	COG1873	PFAM PRC-barrel domain
AS891_RS15040	COG0612	Peptidase, M16
AS891_RS15045	COG0726	polysaccharide deacetylase
AS891_RS15050	COG1185	polyribonucleotide nucleotidyltransferase activity
AS891_RS15055	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AS891_RS15060	COG0196	riboflavin kinase activity
AS891_RS15065	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AS891_RS15070	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AS891_RS15075	COG1550	Protein conserved in bacteria
AS891_RS15080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AS891_RS15085	COG1358	cellular component organization or biogenesis
AS891_RS15090	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AS891_RS15095	COG0195	Participates in both transcription termination and antitermination
AS891_RS15100	COG0779	Required for maturation of 30S ribosomal subunits
AS891_RS15105	COG2176	DNA-directed DNA polymerase activity
AS891_RS15110	COG0442	prolyl-tRNA aminoacylation
AS891_RS15115	COG0750	zinc metalloprotease
AS891_RS15120	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AS891_RS15125	COG4589	Belongs to the CDS family
AS891_RS15130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AS891_RS15135	COG0233	cytoplasmic translational termination
AS891_RS15140	COG0528	UMP kinase activity
AS891_RS15145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AS891_RS15150	COG0052	Belongs to the universal ribosomal protein uS2 family
AS891_RS15160	COG1191	sigma factor activity
AS891_RS15165	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AS891_RS15170	COG1776	CheC inhibitor of MCP methylation
AS891_RS15175	COG0835	chemotaxis
AS891_RS15180	COG0643	Histidine kinase
AS891_RS15180	COG2198	Histidine kinase
AS891_RS15185	COG2201	protein-glutamate methylesterase activity
AS891_RS15190	COG0455	bacterial-type flagellum organization
AS891_RS15195	COG1419	protein localization to endoplasmic reticulum
AS891_RS15200	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AS891_RS15205	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AS891_RS15210	COG1684	flagellar biosynthetic protein fliR
AS891_RS15215	COG1987	bacterial-type flagellum assembly
AS891_RS15220	COG1338	Plays a role in the flagellum-specific transport system
AS891_RS15225	COG3190	flagellar
AS891_RS15230	COG2201	protein-glutamate methylesterase activity
AS891_RS15235	COG1776	CheC inhibitor of MCP methylation
AS891_RS15235	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS891_RS15240	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS891_RS15245	COG1580	Controls the rotational direction of flagella during chemotaxis
AS891_RS15250	COG1582	Flagellar protein (FlbD)
AS891_RS15255	COG4786	Flagellar basal body rod
AS891_RS15260	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AS891_RS15265	COG3144	bacterial-type flagellum assembly
AS891_RS15270	COG3334	PFAM MgtE intracellular
AS891_RS15275	COG2882	bacterial-type flagellum organization
AS891_RS15280	COG1157	protein secretion by the type III secretion system
AS891_RS15285	COG1317	bacterial-type flagellum organization
AS891_RS15290	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS891_RS15295	COG1766	The M ring may be actively involved in energy transduction
AS891_RS15300	COG1677	Flagellar hook-basal body complex protein FliE
AS891_RS15305	COG1558	bacterial-type flagellum-dependent cell motility
AS891_RS15310	COG1815	bacterial-type flagellum-dependent cell motility
AS891_RS15315	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AS891_RS15320	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AS891_RS15325	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AS891_RS15330	COG4974	Belongs to the 'phage' integrase family
AS891_RS15335	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AS891_RS15340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AS891_RS15345	COG0758	DNA mediated transformation
AS891_RS15350	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AS891_RS15355	COG0045	succinate-CoA ligase (ADP-forming) activity
AS891_RS15360	COG2257	FlhB HrpN YscU SpaS Family
AS891_RS15370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AS891_RS15375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AS891_RS15380	COG0335	large ribosomal subunit rRNA binding
AS891_RS15385	COG0336	Belongs to the RNA methyltransferase TrmD family
AS891_RS15390	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AS891_RS15400	COG1837	Belongs to the UPF0109 family
AS891_RS15405	COG0228	four-way junction DNA binding
AS891_RS15410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AS891_RS15415	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AS891_RS15425	COG0552	protein localization to endoplasmic reticulum
AS891_RS15430	COG1196	nuclear chromosome segregation
AS891_RS15435	COG0571	ribonuclease III activity
AS891_RS15445	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS15450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AS891_RS15455	COG0416	fatty acid biosynthetic process
AS891_RS15460	COG1349	DNA-binding transcription factor activity
AS891_RS15460	COG2050	protein possibly involved in aromatic compounds catabolism
AS891_RS15465	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AS891_RS15470	COG1760	l-serine dehydratase
AS891_RS15475	COG1760	l-serine dehydratase
AS891_RS15480	COG1461	Dihydroxyacetone kinase
AS891_RS15485	COG1302	Protein conserved in bacteria
AS891_RS15490	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AS891_RS15500	COG1564	THIamine pyrophosphokinase
AS891_RS15505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AS891_RS15510	COG1162	GTPase activity
AS891_RS15515	COG2815	serine threonine protein kinase
AS891_RS15515	COG0515	serine threonine protein kinase
AS891_RS15520	COG0631	protein serine/threonine phosphatase activity
AS891_RS15525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AS891_RS15530	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AS891_RS15530	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AS891_RS15535	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AS891_RS15540	COG0242	peptide deformylase activity
AS891_RS15545	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AS891_RS15550	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AS891_RS15555	COG1758	RNA polymerase activity
AS891_RS15560	COG0194	GDP metabolic process
AS891_RS15570	COG1561	YicC-like family, N-terminal region
AS891_RS15575	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS891_RS15580	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AS891_RS15585	COG1648	precorrin-2 dehydrogenase activity
AS891_RS15590	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AS891_RS15595	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS891_RS15600	COG0529	Catalyzes the synthesis of activated sulfate
AS891_RS15605	COG2046	Belongs to the sulfate adenylyltransferase family
AS891_RS15610	COG0306	phosphate transporter
AS891_RS15615	COG0175	sulfate reduction
AS891_RS15620	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AS891_RS15625	COG0284	orotidine-5'-phosphate decarboxylase activity
AS891_RS15630	COG0167	dihydroorotate dehydrogenase activity
AS891_RS15635	COG0543	2 iron, 2 sulfur cluster binding
AS891_RS15640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AS891_RS15645	COG0505	Belongs to the CarA family
AS891_RS15650	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AS891_RS15655	COG0540	Belongs to the ATCase OTCase family
AS891_RS15660	COG2233	PERMEase
AS891_RS15665	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AS891_RS15670	COG0564	pseudouridine synthase activity
AS891_RS15675	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AS891_RS15680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS891_RS15685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AS891_RS15690	COG3599	regulation of cell shape
AS891_RS15695	COG2302	S4 RNA-binding domain
AS891_RS15700	COG0762	integral membrane protein
AS891_RS15705	COG1799	cell septum assembly
AS891_RS15710	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AS891_RS15715	COG1496	oxidoreductase activity
AS891_RS15720	COG1873	PFAM PRC-barrel domain
AS891_RS15725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS891_RS15730	COG1119	ATPase activity
AS891_RS15735	COG1191	sigma factor activity
AS891_RS15740	COG1191	sigma factor activity
AS891_RS15750	COG4412	M6 family metalloprotease domain protein
AS891_RS15750	COG1404	Belongs to the peptidase S8 family
AS891_RS15755	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AS891_RS15760	COG0849	cell division
AS891_RS15765	COG3856	small basic protein
AS891_RS15770	COG3879	Bacterial protein of unknown function (DUF881)
AS891_RS15775	COG3879	Bacterial protein of unknown function (DUF881)
AS891_RS15780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AS891_RS15785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AS891_RS15790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS891_RS15795	COG0772	Belongs to the SEDS family
AS891_RS15800	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AS891_RS15805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS891_RS15815	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AS891_RS15825	COG0768	penicillin binding
AS891_RS15835	COG0768	penicillin binding
AS891_RS15840	COG4839	cell division protein FtsL
AS891_RS15845	COG0275	rRNA processing
AS891_RS15850	COG2001	Belongs to the MraZ family
AS891_RS15855	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AS891_RS15860	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS891_RS15865	COG0454	-acetyltransferase
AS891_RS15880	COG1399	metal-binding, possibly nucleic acid-binding protein
AS891_RS15890	COG1323	Belongs to the UPF0348 family
AS891_RS15895	COG3480	Lon protease (S16) C-terminal proteolytic domain
AS891_RS15900	COG1752	Esterase of the alpha-beta hydrolase superfamily
AS891_RS15905	COG3314	Sporulation integral membrane protein YlbJ
AS891_RS15910	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AS891_RS15915	COG0742	ribosomal rna small subunit methyltransferase
AS891_RS15920	COG4471	UPF0298 protein
AS891_RS15925	COG3679	Belongs to the UPF0342 family
AS891_RS15940	COG2340	Cysteine-rich secretory protein family
AS891_RS15945	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AS891_RS15955	COG3336	cytochrome c oxidase
AS891_RS15960	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AS891_RS15965	COG1845	cytochrome c oxidase, subunit III
AS891_RS15970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS891_RS15975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AS891_RS15975	COG2010	Cytochrome c
AS891_RS15980	COG0109	protoheme IX farnesyltransferase activity
AS891_RS15985	COG1612	heme a metabolic process
AS891_RS15990	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AS891_RS15995	COG0772	Belongs to the SEDS family
AS891_RS16000	COG4838	Belongs to the UPF0358 family
AS891_RS16005	COG2066	Belongs to the glutaminase family
AS891_RS16010	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS891_RS16015	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AS891_RS16025	COG4896	Protein conserved in bacteria
AS891_RS16035	COG1217	gtp-binding protein TYPA
AS891_RS16055	COG1595	DNA-templated transcription, initiation
AS891_RS16075	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AS891_RS16085	COG0483	inositol monophosphate 1-phosphatase activity
AS891_RS16095	COG4493	Belongs to the UPF0637 family
AS891_RS16100	COG4476	Belongs to the UPF0223 family
AS891_RS16105	COG1982	Orn Lys Arg decarboxylase major
AS891_RS16110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_RS16115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS891_RS16120	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS891_RS16125	COG0022	dehydrogenase e1 component
AS891_RS16130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS891_RS16135	COG0497	DNA recombination
AS891_RS16145	COG0242	peptide deformylase activity
AS891_RS16150	COG0561	phosphatase activity
AS891_RS16155	COG5503	Protein of unknown function (DUF1447)
AS891_RS16160	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS891_RS16165	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AS891_RS16170	COG0569	domain protein
AS891_RS16175	COG2105	PFAM AIG2 family protein
AS891_RS16175	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AS891_RS16180	COG3852	Histidine kinase
AS891_RS16185	COG2002	toxin-antitoxin pair type II binding
AS891_RS16190	COG1077	Cell shape determining protein MreB Mrl
AS891_RS16200	COG2309	aminopeptidase activity
AS891_RS16205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS891_RS16210	COG0488	(ABC) transporter
AS891_RS16220	COG0681	Belongs to the peptidase S26 family
AS891_RS16225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_RS16225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS891_RS16225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS891_RS16230	COG1105	Belongs to the carbohydrate kinase PfkB family
AS891_RS16235	COG1349	DNA-binding transcription factor activity
AS891_RS16240	COG0577	efflux transmembrane transporter activity
AS891_RS16245	COG1136	(ABC) transporter
AS891_RS16250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AS891_RS16260	COG1132	(ABC) transporter
AS891_RS16265	COG1132	(ABC) transporter
AS891_RS16270	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AS891_RS16275	COG0314	molybdopterin synthase activity
AS891_RS16280	COG1763	Mo-molybdopterin cofactor biosynthetic process
AS891_RS16285	COG0303	'Molybdopterin
AS891_RS16290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS891_RS16295	COG0746	molybdenum cofactor guanylyltransferase activity
AS891_RS16310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_RS16315	COG0450	alkyl hydroperoxide reductase
AS891_RS16320	COG0668	transmembrane transport
AS891_RS16330	COG1473	amidohydrolase
AS891_RS16335	COG2171	N-acyltransferase activity
AS891_RS16340	COG0716	FMN binding
AS891_RS16350	COG0716	FMN binding
AS891_RS16355	COG0583	DNA-binding transcription factor activity
AS891_RS16360	COG0517	IMP dehydrogenase activity
AS891_RS16370	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AS891_RS16375	COG4703	Protein of unknown function (DUF1797)
AS891_RS16385	COG2200	EAL domain
AS891_RS16395	COG3409	Peptidoglycan-binding domain 1 protein
AS891_RS16400	COG3409	Peptidoglycan-binding domain 1 protein
AS891_RS16405	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS16410	COG1408	metallophosphoesterase
AS891_RS16415	COG1376	ErfK ybiS ycfS ynhG family protein
AS891_RS16420	COG2814	Major facilitator Superfamily
AS891_RS16430	COG0835	chemotaxis
AS891_RS16430	COG0784	Response regulator, receiver
AS891_RS16440	COG0436	Aminotransferase
AS891_RS16445	COG4191	Histidine kinase
AS891_RS16450	COG0768	penicillin binding
AS891_RS16455	COG2340	Cysteine-rich secretory protein family
AS891_RS16460	COG2084	Dehydrogenase
AS891_RS16465	COG0840	transmembrane signaling receptor activity
AS891_RS16470	COG0456	acetyltransferase
AS891_RS16475	COG1533	DNA photolyase activity
AS891_RS16485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS891_RS16490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_RS16495	COG1263	PTS System
AS891_RS16495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_RS16495	COG2190	(PTS) system
AS891_RS16500	COG3711	transcriptional antiterminator
AS891_RS16505	COG1609	Transcriptional regulator
AS891_RS16515	COG0006	proline dipeptidase activity
AS891_RS16525	COG2217	Heavy metal translocating P-type atpase
AS891_RS16530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_RS16535	COG2244	polysaccharide biosynthetic process
AS891_RS16540	COG3773	Cell wall hydrolase
AS891_RS16555	COG4873	Protein conserved in bacteria
AS891_RS16565	COG3858	chitin binding
AS891_RS16570	COG3858	chitin binding
AS891_RS16575	COG1388	LysM domain
AS891_RS16580	COG1388	LysM domain
AS891_RS16580	COG4641	Protein conserved in bacteria
AS891_RS16585	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS16590	COG1733	regulation of RNA biosynthetic process
AS891_RS16595	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AS891_RS16600	COG0602	queuosine metabolic process
AS891_RS16605	COG0720	synthase
AS891_RS16610	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AS891_RS16615	COG3949	Membrane
AS891_RS16620	COG0542	response to heat
AS891_RS16625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AS891_RS16630	COG1360	Flagellar Motor Protein
AS891_RS16635	COG1846	Transcriptional regulator
AS891_RS16640	COG3852	Histidine kinase
AS891_RS16655	COG3339	Conserved Protein
AS891_RS16660	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AS891_RS16665	COG0235	Class ii aldolase
AS891_RS16670	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AS891_RS16675	COG1850	ribulose-bisphosphate carboxylase activity
AS891_RS16680	COG0436	Aminotransferase
AS891_RS16685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS891_RS16690	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AS891_RS16695	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AS891_RS16705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS891_RS16710	COG5002	protein histidine kinase activity
AS891_RS16715	COG3594	Acyltransferase
AS891_RS16730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS891_RS16735	COG0501	Belongs to the peptidase M48B family
AS891_RS16755	COG1191	sigma factor activity
AS891_RS16760	COG0861	Integral membrane protein TerC family
AS891_RS16765	COG0586	Pfam SNARE associated Golgi protein
AS891_RS16770	COG5001	Diguanylate cyclase
AS891_RS16770	COG3300	MHYT domain
AS891_RS16775	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AS891_RS16780	COG3285	dna ligase
AS891_RS16780	COG1793	dna ligase
AS891_RS16785	COG0463	Glycosyl transferase, family 2
AS891_RS16795	COG1408	metallophosphoesterase
AS891_RS16800	COG0726	polysaccharide deacetylase
AS891_RS16805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS891_RS16810	COG1846	Transcriptional regulator
AS891_RS16825	COG0789	Transcriptional regulator
AS891_RS16830	COG2239	Acts as a magnesium transporter
AS891_RS16850	COG3212	peptidase
AS891_RS16855	COG3212	peptidase
AS891_RS16860	COG5002	protein histidine kinase activity
AS891_RS16860	COG3850	Histidine kinase
AS891_RS16865	COG0745	RESPONSE REGULATOR receiver
AS891_RS16875	COG4721	ABC-type cobalt transport system, permease component
AS891_RS16880	COG1122	ATPase activity
AS891_RS16885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AS891_RS16890	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_RS16895	COG1404	Belongs to the peptidase S8 family
AS891_RS16900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AS891_RS16905	COG0590	tRNA wobble adenosine to inosine editing
AS891_RS16915	COG1764	response to oxidative stress
AS891_RS16920	COG1846	Transcriptional regulator
AS891_RS16925	COG1764	response to oxidative stress
AS891_RS16930	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AS891_RS16935	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AS891_RS16940	COG0788	formyltetrahydrofolate deformylase activity
AS891_RS16945	COG2076	Multidrug Resistance protein
AS891_RS16950	COG2076	Multidrug Resistance protein
AS891_RS16955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_RS16960	COG2318	DinB family
AS891_RS16965	COG2323	membrane
AS891_RS16975	COG1017	nitric oxide dioxygenase activity
AS891_RS16975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS891_RS16980	COG1607	acyl-coa hydrolase
AS891_RS16985	COG1834	amidinotransferase
AS891_RS16990	COG2706	6-phosphogluconolactonase activity
AS891_RS16995	COG4608	Belongs to the ABC transporter superfamily
AS891_RS17000	COG0791	NLP P60 protein
AS891_RS17005	COG4948	Mandelate Racemase Muconate Lactonizing
AS891_RS17010	COG1619	proteins homologs of microcin C7 resistance protein MccF
AS891_RS17015	COG4166	transmembrane transport
AS891_RS17020	COG0444	Belongs to the ABC transporter superfamily
AS891_RS17025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS891_RS17030	COG0601	transmembrane transport
AS891_RS17035	COG2362	D-Aminopeptidase
AS891_RS17040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS891_RS17045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS891_RS17055	COG0463	Glycosyl transferase, family 2
AS891_RS17060	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AS891_RS17065	COG0346	lactoylglutathione lyase activity
AS891_RS17070	COG0531	amino acid
AS891_RS17075	COG1392	Phosphate transport regulator
AS891_RS17080	COG0306	phosphate transporter
AS891_RS17095	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS891_RS17095	COG3409	Peptidoglycan-binding domain 1 protein
AS891_RS17135	COG3778	Protein conserved in bacteria
AS891_RS17140	COG3299	homolog of phage Mu protein gp47
AS891_RS17145	COG3628	GPW Gp25 family protein
AS891_RS17155	COG4193	domain, Protein
AS891_RS17160	COG1652	LysM domain
AS891_RS17165	COG3953	SLT domain
AS891_RS17165	COG5412	phage tail tape measure protein
AS891_RS17215	COG4653	Phage capsid family
AS891_RS17220	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AS891_RS17225	COG5518	Phage portal protein
AS891_RS17230	COG1783	phage Terminase large subunit
AS891_RS17235	COG3728	DNA packaging
AS891_RS17235	COG5484	DNA packaging
AS891_RS17240	COG1595	DNA-templated transcription, initiation
AS891_RS17265	COG1484	DNA-dependent DNA replication
AS891_RS17270	COG1522	sequence-specific DNA binding
AS891_RS17280	COG1396	sequence-specific DNA binding
AS891_RS17285	COG2856	Zn peptidase
AS891_RS17290	COG3546	catalase activity
AS891_RS17295	COG4195	phage-related replication protein
AS891_RS17305	COG1388	LysM domain
AS891_RS17305	COG3409	Peptidoglycan-binding domain 1 protein
AS891_RS17305	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS891_RS17310	COG2350	Protein conserved in bacteria
AS891_RS17320	COG0457	Tetratricopeptide repeat
AS891_RS17325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS891_RS17330	COG2318	DinB family
AS891_RS17335	COG0730	response to heat
AS891_RS17340	COG2721	sulfolactate sulfo-lyase activity
AS891_RS17345	COG0246	Mannitol dehydrogenase
AS891_RS17350	COG1609	Transcriptional regulator
AS891_RS17355	COG2271	Major facilitator Superfamily
AS891_RS17360	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS17365	COG1312	Catalyzes the dehydration of D-mannonate
AS891_RS17370	COG1063	alcohol dehydrogenase
AS891_RS17375	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AS891_RS17380	COG2211	Major facilitator Superfamily
AS891_RS17385	COG1904	glucuronate isomerase
AS891_RS17390	COG1252	NADH dehydrogenase
AS891_RS17400	COG4297	protein containing double-stranded beta helix domain
AS891_RS17405	COG0697	spore germination
AS891_RS17410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS891_RS17415	COG0390	transport system, permease component
AS891_RS17420	COG1587	Uroporphyrinogen-III synthase
AS891_RS17430	COG1819	glycosyl
AS891_RS17435	COG2124	cytochrome p450
AS891_RS17445	COG1051	belongs to the nudix hydrolase family
AS891_RS17455	COG2427	Protein of unknown function (DUF1641)
AS891_RS17460	COG3383	formate dehydrogenase (NAD+) activity
AS891_RS17470	COG2205	protein histidine kinase activity
AS891_RS17475	COG5504	Zn-dependent protease
AS891_RS17495	COG0726	polysaccharide deacetylase
AS891_RS17505	COG0109	protoheme IX farnesyltransferase activity
AS891_RS17520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AS891_RS17530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_RS17540	COG1482	cell wall glycoprotein biosynthetic process
AS891_RS17545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_RS17545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS891_RS17545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS891_RS17550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_RS17550	COG3711	transcriptional antiterminator
AS891_RS17560	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS17565	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AS891_RS17570	COG5484	DNA packaging
AS891_RS17585	COG3677	Transposase
AS891_RS17620	COG5505	Protein of unknown function (DUF819)
AS891_RS17625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_RS17630	COG0626	cystathionine gamma-synthase activity
AS891_RS17635	COG0626	cystathionine gamma-synthase activity
AS891_RS17640	COG2382	esterase
AS891_RS17645	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AS891_RS17650	COG2153	protein acetylation
AS891_RS17660	COG0210	DNA helicase
AS891_RS17720	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AS891_RS17725	COG0351	phosphomethylpyrimidine kinase
AS891_RS17730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS891_RS17735	COG2022	thiamine diphosphate biosynthetic process
AS891_RS17740	COG2104	thiamine diphosphate biosynthetic process
AS891_RS17745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS891_RS17750	COG0352	thiamine-phosphate diphosphorylase activity
AS891_RS17755	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AS891_RS17760	COG0569	domain protein
AS891_RS17760	COG0475	glutathione-regulated potassium exporter activity
AS891_RS17765	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AS891_RS17770	COG0564	pseudouridine synthase activity
AS891_RS17775	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AS891_RS17780	COG2357	RelA SpoT domain protein
AS891_RS17790	COG4116	CYTH
AS891_RS17795	COG0741	lytic transglycosylase activity
AS891_RS17800	COG2346	COG2346, Truncated hemoglobins
AS891_RS17805	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS891_RS17820	COG1164	Oligoendopeptidase f
AS891_RS17825	COG4469	Competence protein
AS891_RS17830	COG4862	establishment of competence for transformation
AS891_RS17835	COG0861	Integral membrane protein TerC family
AS891_RS17840	COG1393	Belongs to the ArsC family
AS891_RS17845	COG0456	acetyltransferase
AS891_RS17850	COG2814	Major facilitator Superfamily
AS891_RS17855	COG4608	Belongs to the ABC transporter superfamily
AS891_RS17860	COG0444	Belongs to the ABC transporter superfamily
AS891_RS17865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS891_RS17870	COG0601	transmembrane transport
AS891_RS17880	COG0180	Tryptophanyl-tRNA synthetase
AS891_RS17890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS891_RS17895	COG0601	transmembrane transport
AS891_RS17905	COG4608	Belongs to the ABC transporter superfamily
AS891_RS17910	COG0444	Belongs to the ABC transporter superfamily
AS891_RS17915	COG5504	Zn-dependent protease
AS891_RS17920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS891_RS17925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS891_RS17940	COG1744	ABC transporter substrate-binding protein PnrA-like
AS891_RS17950	COG2267	carboxylic ester hydrolase activity
AS891_RS17965	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AS891_RS17970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AS891_RS17975	COG0505	Belongs to the CarA family
AS891_RS17980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS891_RS17990	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AS891_RS17995	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AS891_RS18000	COG2271	Major facilitator Superfamily
AS891_RS18005	COG0277	FAD linked oxidase domain protein
AS891_RS18015	COG2151	metal-sulfur cluster biosynthetic enzyme
AS891_RS18020	COG1073	alpha beta
AS891_RS18025	COG0561	phosphatase activity
AS891_RS18045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_RS18050	COG1307	EDD domain protein, DegV family
AS891_RS18055	COG3227	Zinc metalloprotease (Elastase)
AS891_RS18070	COG1695	Transcriptional regulator
AS891_RS18090	COG2996	Protein conserved in bacteria
AS891_RS18095	COG1666	GTP binding
AS891_RS18100	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AS891_RS18100	COG0646	methionine synthase
AS891_RS18105	COG2153	protein acetylation
AS891_RS18110	COG0454	-acetyltransferase
AS891_RS18115	COG2814	Major facilitator Superfamily
AS891_RS18120	COG4948	Mandelate Racemase Muconate Lactonizing
AS891_RS18125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_RS18130	COG1809	phosphosulfolactate synthase activity
AS891_RS18135	COG2045	Belongs to the ComB family
AS891_RS18140	COG0175	sulfate reduction
AS891_RS18145	COG2046	Belongs to the sulfate adenylyltransferase family
AS891_RS18150	COG0529	Catalyzes the synthesis of activated sulfate
AS891_RS18155	COG2267	carboxylic ester hydrolase activity
AS891_RS18160	COG1357	PFAM Pentapeptide repeats (8 copies)
AS891_RS18165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_RS18170	COG1279	arginine transmembrane transporter activity
AS891_RS18175	COG2318	DinB family
AS891_RS18180	COG0673	inositol 2-dehydrogenase activity
AS891_RS18185	COG1609	Transcriptional regulator
AS891_RS18190	COG1917	Cupin 2, conserved barrel domain protein
AS891_RS18190	COG2207	Transcriptional regulator
AS891_RS18195	COG0534	Mate efflux family protein
AS891_RS18200	COG1562	ergosterol biosynthetic process
AS891_RS18205	COG2318	DinB family
AS891_RS18210	COG0367	asparagine synthase
AS891_RS18220	COG1404	Belongs to the peptidase S8 family
AS891_RS18230	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS891_RS18235	COG5337	Spore coat protein CotH
AS891_RS18280	COG1403	HNH endonuclease
AS891_RS18285	COG0419	ATPase involved in DNA repair
AS891_RS18290	COG0420	3'-5' exonuclease activity
AS891_RS18295	COG1074	ATP-dependent DNA helicase activity
AS891_RS18300	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AS891_RS18305	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AS891_RS18315	COG4533	DNA binding
AS891_RS18320	COG2814	Major facilitator Superfamily
AS891_RS18320	COG0477	Major facilitator Superfamily
AS891_RS18325	COG3180	Ammonia monooxygenase
AS891_RS18330	COG1609	Transcriptional regulator
AS891_RS18335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS891_RS18340	COG0561	phosphatase activity
AS891_RS18345	COG0673	inositol 2-dehydrogenase activity
AS891_RS18350	COG0738	Major facilitator superfamily
AS891_RS18355	COG1846	Transcriptional regulator
AS891_RS18360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS891_RS18365	COG0681	Belongs to the peptidase S26 family
AS891_RS18370	COG0398	Pfam SNARE associated Golgi protein
AS891_RS18385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS891_RS18395	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS18400	COG4903	ComK protein
AS891_RS18410	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS18415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS891_RS18415	COG0723	plastoquinol--plastocyanin reductase activity
AS891_RS18420	COG0840	transmembrane signaling receptor activity
AS891_RS18425	COG1268	BioY protein
AS891_RS18430	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_RS18435	COG0183	Belongs to the thiolase family
AS891_RS18440	COG0406	alpha-ribazole phosphatase activity
AS891_RS18445	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AS891_RS18450	COG0604	alcohol dehydrogenase
AS891_RS18455	COG0456	acetyltransferase
AS891_RS18460	COG1404	Belongs to the peptidase S8 family
AS891_RS18465	COG0501	Belongs to the peptidase M48B family
AS891_RS18475	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_RS18480	COG0702	epimerase
AS891_RS18485	COG0095	Lipoate-protein ligase
AS891_RS18490	COG1234	tRNA 3'-trailer cleavage
AS891_RS18500	COG1301	dicarboxylic acid transport
AS891_RS18505	COG4405	Protein conserved in bacteria
AS891_RS18510	COG1363	Peptidase, m42
AS891_RS18520	COG4377	Putative membrane peptidase family (DUF2324)
AS891_RS18525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS891_RS18530	COG1511	domain protein
AS891_RS18535	COG1309	transcriptional regulator
AS891_RS18540	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AS891_RS18545	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AS891_RS18550	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AS891_RS18555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS891_RS18560	COG2329	Antibiotic biosynthesis monooxygenase
AS891_RS18570	COG3069	C4-dicarboxylate transmembrane transporter activity
AS891_RS18575	COG1473	amidohydrolase
AS891_RS18585	COG4473	ABC transporter
AS891_RS18590	COG1131	(ABC) transporter
AS891_RS18595	COG0537	adenosine 5'-monophosphoramidase activity
AS891_RS18600	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AS891_RS18615	COG4980	gas vesicle protein
AS891_RS18620	COG1846	Transcriptional regulator
AS891_RS18640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AS891_RS18650	COG3481	metal-dependent phosphohydrolase, HD sub domain
AS891_RS18655	COG4717	serine-type aminopeptidase activity
AS891_RS18660	COG0420	3'-5' exonuclease activity
AS891_RS18665	COG1668	transmembrane transport
AS891_RS18670	COG4152	abc transporter atp-binding protein
AS891_RS18680	COG1024	Enoyl-CoA hydratase
AS891_RS18690	COG0490	domain, Protein
AS891_RS18695	COG0475	glutathione-regulated potassium exporter activity
AS891_RS18700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS891_RS18705	COG0561	phosphatase activity
AS891_RS18710	COG4335	DNA alkylation repair
AS891_RS18715	COG3679	Belongs to the UPF0342 family
AS891_RS18720	COG4399	Belongs to the UPF0754 family
AS891_RS18725	COG0189	ligase activity
AS891_RS18730	COG0189	ligase activity
AS891_RS18745	COG0702	epimerase
AS891_RS18750	COG1132	(ABC) transporter
AS891_RS18755	COG1132	(ABC) transporter
AS891_RS18765	COG0589	response to stress
AS891_RS18770	COG1757	Na H antiporter
AS891_RS18775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS891_RS18780	COG0726	polysaccharide deacetylase
AS891_RS18785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AS891_RS18790	COG0668	transmembrane transport
AS891_RS18800	COG0584	glycerophosphoryl diester phosphodiesterase
AS891_RS18805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS891_RS18810	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS891_RS18815	COG1253	flavin adenine dinucleotide binding
AS891_RS18820	COG0436	Aminotransferase
AS891_RS18825	COG0789	Transcriptional regulator
AS891_RS18830	COG1253	flavin adenine dinucleotide binding
AS891_RS18835	COG0204	Acyl-transferase
AS891_RS18840	COG0667	Aldo Keto reductase
AS891_RS18845	COG1595	DNA-templated transcription, initiation
AS891_RS18860	COG0456	acetyltransferase
AS891_RS18865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_RS18870	COG0733	neurotransmitter:sodium symporter activity
AS891_RS18875	COG0531	amino acid
AS891_RS18880	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS18885	COG0372	Belongs to the citrate synthase family
AS891_RS18890	COG0583	DNA-binding transcription factor activity
AS891_RS18895	COG0791	NLP P60 protein
AS891_RS18895	COG1388	LysM domain
AS891_RS18900	COG1785	Belongs to the alkaline phosphatase family
AS891_RS18905	COG2719	SpoVR family
AS891_RS18910	COG0668	transmembrane transport
AS891_RS18915	COG1959	2 iron, 2 sulfur cluster binding
AS891_RS18920	COG0791	NLP P60 protein
AS891_RS18920	COG1388	LysM domain
AS891_RS18935	COG0431	NADPH-dependent FMN reductase
AS891_RS18940	COG2197	response regulator
AS891_RS18945	COG4585	Histidine kinase
AS891_RS18945	COG2203	Gaf domain
AS891_RS18950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS891_RS18955	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AS891_RS18960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS891_RS18965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS891_RS18970	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AS891_RS18975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS891_RS18980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS891_RS18980	COG3153	acetyltransferase
AS891_RS18985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS891_RS18990	COG0517	IMP dehydrogenase activity
AS891_RS19000	COG0564	pseudouridine synthase activity
AS891_RS19005	COG3764	Sortase (surface protein transpeptidase)
AS891_RS19010	COG4085	toxin activity
AS891_RS19010	COG0737	Belongs to the 5'-nucleotidase family
AS891_RS19010	COG1525	nuclease
AS891_RS19015	COG5577	PFAM Coat F domain
AS891_RS19035	COG1823	symporter activity
AS891_RS19040	COG3706	GGDEF domain
AS891_RS19045	COG1464	Belongs to the NlpA lipoprotein family
AS891_RS19055	COG1278	Cold shock
AS891_RS19060	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AS891_RS19065	COG1131	(ABC) transporter
AS891_RS19070	COG1131	(ABC) transporter
AS891_RS19075	COG1725	Transcriptional regulator
AS891_RS19090	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS891_RS19095	COG2814	Major facilitator Superfamily
AS891_RS19100	COG1566	PFAM secretion protein HlyD family protein
AS891_RS19105	COG1846	Transcriptional regulator
AS891_RS19115	COG2718	Belongs to the UPF0229 family
AS891_RS19120	COG2766	serine protein kinase
AS891_RS19125	COG1664	Polymer-forming cytoskeletal
AS891_RS19130	COG1664	Polymer-forming cytoskeletal
AS891_RS19135	COG0789	Transcriptional regulator
AS891_RS19140	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AS891_RS19150	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AS891_RS19155	COG3382	B3 4 domain protein
AS891_RS19165	COG1476	TRANSCRIPTIONal
AS891_RS19175	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AS891_RS19185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_RS19190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS891_RS19195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS891_RS19200	COG1116	anion transmembrane transporter activity
AS891_RS19205	COG0753	catalase activity
AS891_RS19215	COG0277	FAD linked oxidase domain protein
AS891_RS19220	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AS891_RS19225	COG3340	Belongs to the peptidase S51 family
AS891_RS19230	COG5577	PFAM Coat F domain
AS891_RS19240	COG4326	sporulation control protein
AS891_RS19355	COG0735	belongs to the Fur family
AS891_RS19360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS891_RS19365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AS891_RS19370	COG4129	membrane
AS891_RS19375	COG1132	(ABC) transporter
AS891_RS19380	COG3557	Belongs to the UPF0374 family
AS891_RS19395	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS19405	COG1194	a g-specific adenine glycosylase
AS891_RS19410	COG1988	membrane-bound metal-dependent
AS891_RS19415	COG4485	Bacterial membrane protein, YfhO
AS891_RS19420	COG0463	Glycosyl transferase, family 2
AS891_RS19425	COG0596	Alpha beta hydrolase
AS891_RS19430	COG5658	integral membrane protein
AS891_RS19435	COG3103	Sh3 type 3 domain protein
AS891_RS19450	COG2814	Major facilitator Superfamily
AS891_RS19465	COG2137	regulation of response to DNA damage stimulus
AS891_RS19470	COG1090	epimerase
AS891_RS19485	COG0778	Nitroreductase
AS891_RS19490	COG0384	phenazine biosynthesis protein PhzF
AS891_RS19495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_RS19500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_RS19505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS891_RS19510	COG0392	lysyltransferase activity
AS891_RS19510	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AS891_RS19515	COG1846	Transcriptional regulator
AS891_RS19520	COG2814	Major facilitator Superfamily
AS891_RS19525	COG2318	DinB family
AS891_RS19530	COG2814	Major facilitator Superfamily
AS891_RS19535	COG1309	transcriptional regulator
AS891_RS19540	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AS891_RS19545	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AS891_RS19550	COG1695	Transcriptional regulator
AS891_RS19555	COG0842	Transport permease protein
AS891_RS19560	COG0842	Transport permease protein
AS891_RS19560	COG1511	domain protein
AS891_RS19565	COG1131	(ABC) transporter
AS891_RS19570	COG2197	response regulator
AS891_RS19575	COG4585	Histidine kinase
AS891_RS19580	COG0673	inositol 2-dehydrogenase activity
AS891_RS19585	COG1082	Xylose isomerase domain protein TIM barrel
AS891_RS19590	COG2814	Major facilitator Superfamily
AS891_RS19595	COG1917	Cupin 2, conserved barrel domain protein
AS891_RS19595	COG4977	sequence-specific DNA binding
AS891_RS19600	COG2514	catechol 2,3-dioxygenase activity
AS891_RS19605	COG2259	Doxx family
AS891_RS19610	COG1132	(ABC) transporter
AS891_RS19615	COG1132	(ABC) transporter
AS891_RS19620	COG1263	PTS System
AS891_RS19620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_RS19625	COG1737	Transcriptional regulator
AS891_RS19630	COG1486	melibiose metabolic process
AS891_RS19635	COG4842	Belongs to the WXG100 family
AS891_RS19660	COG1742	UPF0060 membrane protein
AS891_RS19670	COG3284	Transcriptional regulator
AS891_RS19675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS891_RS19680	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS891_RS19685	COG0022	dehydrogenase e1 component
AS891_RS19690	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS891_RS19700	COG4637	Psort location Cytoplasmic, score
AS891_RS19705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AS891_RS19715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AS891_RS19720	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AS891_RS19725	COG0598	Magnesium transport protein CorA
AS891_RS19730	COG2084	Dehydrogenase
AS891_RS19735	COG0726	polysaccharide deacetylase
AS891_RS19745	COG0535	radical SAM domain protein
AS891_RS19750	COG0668	transmembrane transport
AS891_RS19760	COG0387	Pfam Sodium calcium exchanger
AS891_RS19770	COG0477	Major facilitator Superfamily
AS891_RS19780	COG1295	ribonuclease BN
AS891_RS19785	COG4980	gas vesicle protein
AS891_RS19790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS891_RS19795	COG4840	Belongs to the UPF0435 family
AS891_RS19800	COG2814	Major facilitator Superfamily
AS891_RS19805	COG0693	protein deglycase activity
AS891_RS19810	COG0737	Belongs to the 5'-nucleotidase family
AS891_RS19815	COG0778	Nitroreductase
AS891_RS19820	COG2188	Transcriptional regulator
AS891_RS19825	COG0366	Alpha amylase catalytic
AS891_RS19830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_RS19830	COG1263	PTS System
AS891_RS19835	COG0697	spore germination
AS891_RS19850	COG0531	amino acid
AS891_RS19855	COG1115	amino acid carrier protein
AS891_RS19865	COG1368	sulfuric ester hydrolase activity
AS891_RS19870	COG1263	PTS System
AS891_RS19870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_RS19875	COG0024	Methionine aminopeptidase
AS891_RS19895	COG2258	MOSC domain
AS891_RS19900	COG1254	Belongs to the acylphosphatase family
AS891_RS19905	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AS891_RS19910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_RS19915	COG2851	Citrate transporter
AS891_RS19925	COG3181	Tripartite tricarboxylate transporter family receptor
AS891_RS19930	COG4565	transcriptional regulatory protein
AS891_RS19935	COG3290	protein histidine kinase activity
AS891_RS19940	COG0471	metal ion transport
AS891_RS19945	COG3866	Pectate lyase
AS891_RS19960	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AS891_RS19965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_RS19970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_RS19975	COG1120	ATPase activity
AS891_RS19980	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS891_RS19985	COG2211	Major facilitator Superfamily
AS891_RS20000	COG2130	NADP-dependent
AS891_RS20005	COG0456	acetyltransferase
AS891_RS20010	COG0513	Belongs to the DEAD box helicase family
AS891_RS20015	COG0488	(ABC) transporter
AS891_RS20030	COG2814	Major facilitator Superfamily
AS891_RS20035	COG0789	Transcriptional regulator
AS891_RS20045	COG0488	(ABC) transporter
AS891_RS20050	COG0840	transmembrane signaling receptor activity
AS891_RS20055	COG1012	belongs to the aldehyde dehydrogenase family
AS891_RS20060	COG0531	amino acid
AS891_RS20065	COG1011	Hydrolase
AS891_RS20070	COG2223	nitrite transmembrane transporter activity
AS891_RS20075	COG1442	glycosyl transferase family 8
AS891_RS20080	COG1216	Glycosyl transferase, family 2
AS891_RS20085	COG1442	glycosyl transferase family 8
AS891_RS20090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS891_RS20095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AS891_RS20100	COG1368	sulfuric ester hydrolase activity
AS891_RS20105	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AS891_RS20105	COG2124	cytochrome p450
AS891_RS20115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS891_RS20120	COG1846	Transcriptional regulator
AS891_RS20125	COG0697	spore germination
AS891_RS20130	COG0670	Belongs to the BI1 family
AS891_RS20135	COG5583	Uncharacterized small protein (DUF2292)
AS891_RS20150	COG0346	lactoylglutathione lyase activity
AS891_RS20155	COG2329	Antibiotic biosynthesis monooxygenase
AS891_RS20160	COG2323	membrane
AS891_RS20165	COG1486	melibiose metabolic process
AS891_RS20170	COG0395	ABC-type sugar transport system, permease component
AS891_RS20175	COG4209	transmembrane transport
AS891_RS20180	COG1653	transport
AS891_RS20190	COG1874	Beta-galactosidase
AS891_RS20195	COG2755	lipolytic protein G-D-S-L family
AS891_RS20200	COG3401	FG-GAP repeat protein
AS891_RS20205	COG3401	FG-GAP repeat protein
AS891_RS20210	COG5578	integral membrane protein
AS891_RS20220	COG2755	lipolytic protein G-D-S-L family
AS891_RS20225	COG2207	Transcriptional regulator
AS891_RS20230	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AS891_RS20235	COG0395	ABC-type sugar transport system, permease component
AS891_RS20240	COG1175	transmembrane transport
AS891_RS20245	COG1653	transport
AS891_RS20250	COG4753	response regulator
AS891_RS20250	COG2207	Transcriptional regulator
AS891_RS20255	COG2972	Histidine kinase
AS891_RS20260	COG5578	integral membrane protein
AS891_RS20270	COG0454	-acetyltransferase
AS891_RS20275	COG3546	catalase activity
AS891_RS20290	COG0702	epimerase
AS891_RS20295	COG3631	Ketosteroid isomerase-related protein
AS891_RS20300	COG1309	transcriptional regulator
AS891_RS20310	COG0217	transcriptional regulatory protein
AS891_RS20320	COG0457	Tetratricopeptide repeat
AS891_RS20325	COG3391	amine dehydrogenase activity
AS891_RS20330	COG5444	nuclease activity
AS891_RS20350	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AS891_RS20355	COG1061	Type III restriction enzyme res subunit
AS891_RS20360	COG1002	Type II restriction enzyme, methylase subunits
AS891_RS20365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS891_RS20370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS891_RS20375	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AS891_RS20380	COG1597	lipid kinase activity
AS891_RS20385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS891_RS20390	COG1309	transcriptional regulator
AS891_RS20395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AS891_RS20400	COG0154	amidase activity
AS891_RS20405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AS891_RS20410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS891_RS20415	COG1285	pathogenesis
AS891_RS20420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS891_RS20425	COG4851	CamS sex pheromone cAM373 precursor
AS891_RS20430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AS891_RS20435	COG0210	DNA helicase
AS891_RS20440	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AS891_RS20450	COG0069	glutamate synthase activity
AS891_RS20455	COG4496	protein, YerC YecD
AS891_RS20460	COG1470	cell adhesion involved in biofilm formation
AS891_RS20465	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AS891_RS20475	COG0531	amino acid
AS891_RS20480	COG1522	sequence-specific DNA binding
AS891_RS20485	COG0151	Belongs to the GarS family
AS891_RS20490	COG0138	bifunctional purine biosynthesis protein purh
AS891_RS20495	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AS891_RS20500	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AS891_RS20505	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AS891_RS20510	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS891_RS20515	COG0047	phosphoribosylformylglycinamidine synthase activity
AS891_RS20520	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS891_RS20525	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AS891_RS20530	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AS891_RS20535	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AS891_RS20540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AS891_RS20550	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AS891_RS20560	COG3064	Membrane
AS891_RS20565	COG2252	PERMEase
AS891_RS20570	COG0519	Catalyzes the synthesis of GMP from XMP
AS891_RS20570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AS891_RS20575	COG1305	Transglutaminase-like
AS891_RS20580	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AS891_RS20585	COG0714	Associated with various cellular activities
AS891_RS20590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS891_RS20600	COG1113	amino acid transport
AS891_RS20605	COG2132	Multicopper oxidase
AS891_RS20615	COG2267	carboxylic ester hydrolase activity
AS891_RS20630	COG0823	Involved in the tonB-independent uptake of proteins
AS891_RS20635	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AS891_RS20640	COG1063	alcohol dehydrogenase
AS891_RS20645	COG2814	Major facilitator Superfamily
AS891_RS20655	COG4260	virion core protein, lumpy skin disease virus
AS891_RS20660	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AS891_RS20665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AS891_RS20670	COG1842	Phage shock protein A
AS891_RS20675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS891_RS20680	COG2211	Major facilitator Superfamily
AS891_RS20685	COG1063	alcohol dehydrogenase
AS891_RS20690	COG0457	Tetratricopeptide repeat
AS891_RS20695	COG1073	alpha beta
AS891_RS20710	COG1401	restriction endodeoxyribonuclease activity
AS891_RS20730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS891_RS20735	COG0270	DNA (cytosine-5-)-methyltransferase activity
AS891_RS20740	COG0270	DNA (cytosine-5-)-methyltransferase activity
AS891_RS20755	COG3378	Phage plasmid primase P4 family
AS891_RS20770	COG0459	protein refolding
AS891_RS20780	COG1266	CAAX protease self-immunity
AS891_RS20790	COG0805	protein transport
AS891_RS20795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS891_RS20800	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AS891_RS20805	COG0315	cyclic pyranopterin monophosphate synthase activity
AS891_RS20810	COG0488	(ABC) transporter
AS891_RS20815	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AS891_RS20820	COG0456	acetyltransferase
AS891_RS20825	COG1214	PFAM Peptidase M22, glycoprotease
AS891_RS20830	COG0802	atpase or kinase
AS891_RS20835	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AS891_RS20880	COG4124	Belongs to the glycosyl hydrolase 26 family
AS891_RS20885	COG1482	cell wall glycoprotein biosynthetic process
AS891_RS20890	COG1940	carbohydrate kinase activity
AS891_RS20895	COG2188	Transcriptional regulator
AS891_RS20900	COG2723	6-phospho-beta-galactosidase activity
AS891_RS20905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS891_RS20910	COG1447	Phosphotransferase system cellobiose-specific component IIA
AS891_RS20915	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS891_RS20920	COG2814	Major facilitator Superfamily
AS891_RS20925	COG1388	LysM domain
AS891_RS20930	COG1078	dGTPase activity
AS891_RS20935	COG0454	-acetyltransferase
AS891_RS20945	COG5646	InterPro IPR014922
AS891_RS20950	COG1785	Belongs to the alkaline phosphatase family
AS891_RS20960	COG1819	glycosyl
AS891_RS20965	COG3858	chitin binding
AS891_RS20965	COG1388	LysM domain
AS891_RS20970	COG1802	Transcriptional regulator
AS891_RS20975	COG0730	response to heat
AS891_RS20980	COG2814	Major facilitator Superfamily
AS891_RS20985	COG1846	Transcriptional regulator
AS891_RS20990	COG0778	Nitroreductase
AS891_RS20995	COG1033	growth of symbiont in host cell
AS891_RS20995	COG2409	Drug exporters of the RND superfamily
AS891_RS21000	COG1846	Transcriptional regulator
AS891_RS21005	COG2318	DinB family
AS891_RS21010	COG1113	amino acid transport
AS891_RS21015	COG0488	(ABC) transporter
AS891_RS21020	COG0456	acetyltransferase
AS891_RS21030	COG1309	transcriptional regulator
AS891_RS21045	COG0071	Belongs to the small heat shock protein (HSP20) family
AS891_RS21050	COG2323	membrane
AS891_RS21055	COG2323	membrane
AS891_RS21075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_RS21080	COG2259	Doxx family
AS891_RS21085	COG0346	lactoylglutathione lyase activity
AS891_RS21090	COG0778	Nitroreductase
AS891_RS21095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS891_RS21100	COG4978	Transcriptional regulator
AS891_RS21100	COG0789	Transcriptional regulator
AS891_RS21105	COG1811	Na channel or pump
AS891_RS21110	COG0596	Alpha beta hydrolase
AS891_RS21115	COG2409	Drug exporters of the RND superfamily
AS891_RS21120	COG2197	response regulator
AS891_RS21125	COG4585	Histidine kinase
AS891_RS21135	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS891_RS21140	COG0640	Transcriptional regulator
AS891_RS21145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS891_RS21150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_RS21155	COG0697	spore germination
AS891_RS21160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_RS21170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS891_RS21175	COG0640	Transcriptional regulator
AS891_RS21185	COG1309	transcriptional regulator
AS891_RS21190	COG2814	Major facilitator Superfamily
AS891_RS21195	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS891_RS21200	COG1733	regulation of RNA biosynthetic process
AS891_RS21205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_RS21210	COG1733	regulation of RNA biosynthetic process
AS891_RS21215	COG3545	Serine hydrolase
AS891_RS21220	COG2030	dehydratase
AS891_RS21225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_RS21230	COG0697	spore germination
AS891_RS21240	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AS891_RS21250	COG0477	Major facilitator Superfamily
AS891_RS21255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_RS21260	COG3708	Transcriptional regulator
AS891_RS21260	COG2207	Transcriptional regulator
AS891_RS21265	COG0697	spore germination
AS891_RS21270	COG2207	Transcriptional regulator
AS891_RS21270	COG1917	Cupin 2, conserved barrel domain protein
AS891_RS21275	COG0697	spore germination
AS891_RS21280	COG1329	Transcriptional regulator
AS891_RS21285	COG1278	Cold shock
AS891_RS21290	COG0693	protein deglycase activity
AS891_RS21310	COG2814	Major facilitator Superfamily
AS891_RS21315	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AS891_RS21320	COG1335	isochorismatase
AS891_RS21325	COG1522	sequence-specific DNA binding
AS891_RS21330	COG1522	sequence-specific DNA binding
AS891_RS21335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_RS21345	COG0457	Tetratricopeptide repeat
AS891_RS21365	COG0741	lytic transglycosylase activity
AS891_RS21365	COG0791	NLP P60 protein
AS891_RS21370	COG5644	endopeptidase inhibitor activity
AS891_RS21380	COG0433	COG0433 Predicted ATPase
AS891_RS21415	COG2946	Replication initiation factor
AS891_RS21420	COG1674	ftsk spoiiie
AS891_RS21445	COG1396	sequence-specific DNA binding
AS891_RS21450	COG2856	Zn peptidase
AS891_RS21455	COG0582	viral genome integration into host DNA
AS891_RS21495	COG3091	SprT-like family
AS891_RS21505	COG2183	response to ionizing radiation
AS891_RS21510	COG1846	Transcriptional regulator
AS891_RS21515	COG1673	EVE domain
AS891_RS21530	COG2208	phosphoserine phosphatase activity
AS891_RS21535	COG1191	sigma factor activity
AS891_RS21540	COG2172	sigma factor antagonist activity
AS891_RS21545	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_RS21550	COG2208	phosphoserine phosphatase activity
AS891_RS21555	COG2172	sigma factor antagonist activity
AS891_RS21560	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_RS21565	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_RS21570	COG2337	Toxic component of a toxin-antitoxin (TA) module
AS891_RS21575	COG0864	Transcriptional regulator
AS891_RS21580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AS891_RS21585	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AS891_RS21590	COG0736	holo-[acyl-carrier-protein] synthase activity
AS891_RS21595	COG0705	Rhomboid family
AS891_RS21600	COG3428	Bacterial PH domain
AS891_RS21605	COG3402	PFAM membrane-flanked domain
AS891_RS21610	COG0513	Belongs to the DEAD box helicase family
AS891_RS21615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AS891_RS21620	COG1181	Belongs to the D-alanine--D-alanine ligase family
AS891_RS21625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_RS21630	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS891_RS21645	COG1960	acyl-CoA dehydrogenase activity
AS891_RS21655	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AS891_RS21660	COG1131	(ABC) transporter
AS891_RS21670	COG0628	permease
AS891_RS21675	COG1301	dicarboxylic acid transport
AS891_RS21680	COG4565	transcriptional regulatory protein
AS891_RS21685	COG3290	protein histidine kinase activity
AS891_RS21690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AS891_RS21695	COG3546	catalase activity
AS891_RS21700	COG2329	Antibiotic biosynthesis monooxygenase
AS891_RS21705	COG0662	Cupin 2, conserved barrel domain protein
AS891_RS21710	COG3729	General stress protein
AS891_RS21715	COG2217	Heavy metal translocating P-type atpase
AS891_RS21720	COG4876	unkown
AS891_RS21725	COG2261	transglycosylase associated protein
AS891_RS21730	COG1914	H( )-stimulated, divalent metal cation uptake system
AS891_RS21745	COG0028	Belongs to the TPP enzyme family
AS891_RS21750	COG0494	nUDIX hydrolase
AS891_RS21755	COG0531	amino acid
AS891_RS21765	COG1215	transferase activity, transferring glycosyl groups
AS891_RS21770	COG5298	Protein conserved in bacteria
AS891_RS21775	COG3706	GGDEF domain
AS891_RS21780	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AS891_RS21785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AS891_RS21785	COG0551	DNA topoisomerase type I activity
AS891_RS21790	COG1522	sequence-specific DNA binding
AS891_RS21795	COG2814	Major facilitator Superfamily
AS891_RS21805	COG3871	stress protein (general stress protein 26)
AS891_RS21810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_RS21815	COG1917	Cupin 2, conserved barrel domain protein
AS891_RS21820	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS21825	COG2226	methyltransferase
AS891_RS21830	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_RS21835	COG3711	transcriptional antiterminator
AS891_RS21840	COG4989	oxidoreductase activity
AS891_RS21845	COG0768	penicillin binding
AS891_RS21850	COG2329	Antibiotic biosynthesis monooxygenase
AS891_RS21860	COG2755	lipolytic protein G-D-S-L family
AS891_RS21865	COG1414	Transcriptional regulator
AS891_RS21870	COG1984	allophanate hydrolase subunit 2
AS891_RS21875	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AS891_RS21880	COG4336	lyase activity
AS891_RS21885	COG1914	H( )-stimulated, divalent metal cation uptake system
AS891_RS21890	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AS891_RS21895	COG0561	phosphatase activity
AS891_RS21905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AS891_RS21910	COG0412	Dienelactone hydrolase
AS891_RS21920	COG0681	Belongs to the peptidase S26 family
AS891_RS21925	COG0473	3-isopropylmalate dehydrogenase activity
AS891_RS21930	COG0246	Mannitol dehydrogenase
AS891_RS21935	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_RS21940	COG2213	PTS system mannitol-specific
AS891_RS21950	COG1349	DNA-binding transcription factor activity
AS891_RS21955	COG1276	copper resistance
AS891_RS21955	COG2372	response to copper ion
AS891_RS21960	COG4549	nuclear export factor GLE1
AS891_RS21965	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_RS21970	COG4975	Glucose uptake
AS891_RS21975	COG1012	belongs to the aldehyde dehydrogenase family
AS891_RS21980	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS891_RS21985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_RS21990	COG0640	Transcriptional regulator
AS891_RS21995	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AS891_RS22000	COG0778	Nitroreductase
AS891_RS22005	COG1309	transcriptional regulator
AS891_RS22010	COG2814	Major facilitator Superfamily
AS891_RS22015	COG4607	ABC-type enterochelin transport system periplasmic component
AS891_RS22020	COG4604	ABC transporter, ATP-binding protein
AS891_RS22025	COG4605	iron ion homeostasis
AS891_RS22030	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_RS22035	COG0527	aspartate kinase activity
AS891_RS22050	COG0457	Tetratricopeptide repeat
AS891_RS22055	COG3850	Histidine kinase
AS891_RS22055	COG5002	protein histidine kinase activity
AS891_RS22060	COG0745	RESPONSE REGULATOR receiver
AS891_RS22065	COG0577	efflux transmembrane transporter activity
AS891_RS22070	COG1136	(ABC) transporter
AS891_RS22075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AS891_RS22085	COG0697	spore germination
AS891_RS22095	COG5434	Belongs to the glycosyl hydrolase 28 family
AS891_RS22100	COG3104	oligopeptide transport
AS891_RS22105	COG0596	Alpha beta hydrolase
AS891_RS22120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AS891_RS22125	COG0163	prenyltransferase activity
AS891_RS22130	COG0583	DNA-binding transcription factor activity
AS891_RS22135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_RS22140	COG0765	amino acid transport
AS891_RS22145	COG1126	abc transporter atp-binding protein
AS891_RS22150	COG2364	Membrane
AS891_RS22160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_RS22165	COG0697	spore germination
AS891_RS22175	COG2814	Major facilitator Superfamily
AS891_RS22180	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AS891_RS22185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity