locus-tag	class	description
KP952_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KP952_RS00010	COG0592	DNA-directed DNA polymerase activity
KP952_RS00015	COG2501	S4 domain
KP952_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KP952_RS00030	COG0187	DNA topoisomerase II activity
KP952_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KP952_RS00070	COG0516	GMP reductase activity
KP952_RS00070	COG0517	IMP dehydrogenase activity
KP952_RS00075	COG1686	Belongs to the peptidase S11 family
KP952_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KP952_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KP952_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KP952_RS00100	COG1428	Deoxynucleoside kinase
KP952_RS00105	COG1428	Deoxynucleoside kinase
KP952_RS00110	COG1388	LysM domain
KP952_RS00110	COG3858	chitin binding
KP952_RS00115	COG1335	isochorismatase
KP952_RS00120	COG0590	tRNA wobble adenosine to inosine editing
KP952_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KP952_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KP952_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KP952_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KP952_RS00190	COG3853	Toxic anion resistance protein (TelA)
KP952_RS00195	COG1982	Orn Lys Arg decarboxylase major
KP952_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KP952_RS00205	COG3870	Protein conserved in bacteria
KP952_RS00210	COG1728	Protein conserved in bacteria
KP952_RS00215	COG0470	DNA polymerase III
KP952_RS00220	COG1774	PSP1 C-terminal conserved region
KP952_RS00225	COG4467	Involved in initiation control of chromosome replication
KP952_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KP952_RS00235	COG2827	Endonuclease containing a URI domain
KP952_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KP952_RS00245	COG2002	toxin-antitoxin pair type II binding
KP952_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KP952_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KP952_RS00255	COG0084	hydrolase, TatD family'
KP952_RS00260	COG3583	domain protein
KP952_RS00260	COG3584	3D domain protein
KP952_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KP952_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KP952_RS00280	COG4466	Protein conserved in bacteria
KP952_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KP952_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KP952_RS00300	COG0251	oxidation-reduction process
KP952_RS00305	COG2088	sporulation resulting in formation of a cellular spore
KP952_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KP952_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KP952_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KP952_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
KP952_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KP952_RS00340	COG2002	toxin-antitoxin pair type II binding
KP952_RS00345	COG2244	polysaccharide biosynthetic process
KP952_RS00350	COG3956	TIGRFAM MazG family protein
KP952_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KP952_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KP952_RS00375	COG1098	S1 RNA binding domain
KP952_RS00390	COG2208	phosphoserine phosphatase activity
KP952_RS00395	COG2304	oxidoreductase activity
KP952_RS00400	COG0515	serine threonine protein kinase
KP952_RS00405	COG0037	tRNA processing
KP952_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KP952_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KP952_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KP952_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KP952_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KP952_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KP952_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KP952_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
KP952_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KP952_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KP952_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KP952_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KP952_RS00470	COG1396	sequence-specific DNA binding
KP952_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KP952_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KP952_RS00560	COG4463	regulation of RNA biosynthetic process
KP952_RS00565	COG3880	PFAM UvrB UvrC protein
KP952_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KP952_RS00575	COG0542	response to heat
KP952_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KP952_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KP952_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
KP952_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KP952_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KP952_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KP952_RS00610	COG1045	serine acetyltransferase
KP952_RS00615	COG0215	cysteine-tRNA ligase activity
KP952_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KP952_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KP952_RS00630	COG3688	RNA-binding protein containing a PIN domain
KP952_RS00635	COG1595	DNA-templated transcription, initiation
KP952_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KP952_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
KP952_RS00660	COG0081	regulation of translation
KP952_RS00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KP952_RS00675	COG2813	Specifically methylates the guanine in position
KP952_RS00680	COG0085	RNA polymerase activity
KP952_RS00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KP952_RS00690	COG1358	cellular component organization or biogenesis
KP952_RS00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KP952_RS00700	COG0049	tRNA binding
KP952_RS00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KP952_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KP952_RS00715	COG0596	Alpha beta hydrolase
KP952_RS00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KP952_RS00730	COG0088	Forms part of the polypeptide exit tunnel
KP952_RS00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KP952_RS00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KP952_RS00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KP952_RS00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KP952_RS00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KP952_RS00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KP952_RS00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KP952_RS00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KP952_RS00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KP952_RS00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KP952_RS00820	COG0200	Binds to the 23S rRNA
KP952_RS00825	COG0201	protein transport
KP952_RS00830	COG0563	adenylate kinase activity
KP952_RS00835	COG0024	Methionine aminopeptidase
KP952_RS00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
KP952_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KP952_RS00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KP952_RS00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KP952_RS00865	COG0202	RNA polymerase activity
KP952_RS00870	COG0203	ribosomal protein L17
KP952_RS00875	COG1122	ATPase activity
KP952_RS00880	COG1122	ATPase activity
KP952_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KP952_RS00890	COG0101	tRNA pseudouridine synthase activity
KP952_RS00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KP952_RS00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KP952_RS00905	COG2226	methyltransferase
KP952_RS00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
KP952_RS00920	COG0489	protein tyrosine kinase activity
KP952_RS00930	COG2194	sulfuric ester hydrolase activity
KP952_RS00935	COG0726	polysaccharide deacetylase
KP952_RS01015	COG0659	secondary active sulfate transmembrane transporter activity
KP952_RS01020	COG0385	Bile acid
KP952_RS01025	COG2819	hydrolase of the alpha beta superfamily
KP952_RS01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KP952_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KP952_RS01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KP952_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KP952_RS01045	COG2207	Transcriptional regulator
KP952_RS01055	COG1472	Belongs to the glycosyl hydrolase 3 family
KP952_RS01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KP952_RS01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KP952_RS01065	COG1263	PTS System
KP952_RS01070	COG1737	Transcriptional regulator
KP952_RS01075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KP952_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KP952_RS01085	COG1683	Conserved Protein
KP952_RS01115	COG1595	DNA-templated transcription, initiation
KP952_RS01120	COG5662	AntiSigma factor
KP952_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KP952_RS01130	COG4856	YbbR-like protein
KP952_RS01135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KP952_RS01140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KP952_RS01155	COG2169	Transcriptional regulator
KP952_RS01160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KP952_RS01165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KP952_RS01170	COG3002	Belongs to the UPF0753 family
KP952_RS01175	COG0288	reversible hydration of carbon dioxide
KP952_RS01185	COG5609	conserved protein (DUF2294)
KP952_RS01205	COG0515	serine threonine protein kinase
KP952_RS01220	COG1113	amino acid transport
KP952_RS01235	COG2602	Beta-lactamase
KP952_RS01240	COG2124	cytochrome p450
KP952_RS01250	COG0531	amino acid
KP952_RS01255	COG0584	glycerophosphoryl diester phosphodiesterase
KP952_RS01260	COG2271	Major facilitator Superfamily
KP952_RS01270	COG0456	acetyltransferase
KP952_RS01270	COG1846	Transcriptional regulator
KP952_RS01285	COG3409	Peptidoglycan-binding domain 1 protein
KP952_RS01295	COG1917	Cupin 2, conserved barrel domain protein
KP952_RS01295	COG2207	Transcriptional regulator
KP952_RS01320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KP952_RS01325	COG3591	Belongs to the peptidase S1B family
KP952_RS01335	COG0596	Alpha beta hydrolase
KP952_RS01340	COG1183	phosphatidylcholine synthase activity
KP952_RS01345	COG0586	Pfam SNARE associated Golgi protein
KP952_RS01350	COG0688	phosphatidylethanolamine metabolic process
KP952_RS01360	COG2312	Erythromycin esterase
KP952_RS01365	COG2207	Transcriptional regulator
KP952_RS01370	COG1054	Belongs to the UPF0176 family
KP952_RS01375	COG1301	dicarboxylic acid transport
KP952_RS01380	COG1263	PTS System
KP952_RS01380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KP952_RS01380	COG2190	(PTS) system
KP952_RS01385	COG0363	glucosamine-6-phosphate deaminase activity
KP952_RS01390	COG2188	Transcriptional regulator
KP952_RS01400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KP952_RS01405	COG0833	amino acid
KP952_RS01410	COG2040	homocysteine
KP952_RS01420	COG2066	Belongs to the glutaminase family
KP952_RS01425	COG4191	Histidine kinase
KP952_RS01430	COG0784	Response regulator, receiver
KP952_RS01435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KP952_RS01440	COG1012	belongs to the aldehyde dehydrogenase family
KP952_RS01445	COG2271	Major facilitator Superfamily
KP952_RS01450	COG4948	Mandelate Racemase Muconate Lactonizing
KP952_RS01455	COG2186	Transcriptional regulator
KP952_RS01460	COG2721	sulfolactate sulfo-lyase activity
KP952_RS01465	COG3173	Aminoglycoside phosphotransferase
KP952_RS01475	COG0697	spore germination
KP952_RS01480	COG0745	RESPONSE REGULATOR receiver
KP952_RS01485	COG2205	protein histidine kinase activity
KP952_RS01490	COG1131	(ABC) transporter
KP952_RS01510	COG3773	Cell wall hydrolase
KP952_RS01515	COG2304	oxidoreductase activity
KP952_RS01525	COG3540	Alkaline phosphatase
KP952_RS01530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KP952_RS01535	COG0805	protein transport
KP952_RS01540	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KP952_RS01545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KP952_RS01550	COG0477	Major facilitator Superfamily
KP952_RS01555	COG1309	transcriptional regulator
KP952_RS01560	COG0252	asparaginase activity
KP952_RS01565	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KP952_RS01570	COG1714	RDD family
KP952_RS01575	COG1405	negative regulation of cell septum assembly
KP952_RS01575	COG3012	SEC-C Motif Domain Protein
KP952_RS01585	COG3279	Response regulator of the LytR AlgR family
KP952_RS01590	COG4555	ABC transporter
KP952_RS01595	COG1668	transmembrane transport
KP952_RS01615	COG1595	DNA-templated transcription, initiation
KP952_RS01620	COG1595	DNA-templated transcription, initiation
KP952_RS01625	COG1876	peptidase activity
KP952_RS01635	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS01640	COG0366	Alpha amylase catalytic
KP952_RS01645	COG0803	Belongs to the bacterial solute-binding protein 9 family
KP952_RS01650	COG1121	(ABC) transporter
KP952_RS01655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KP952_RS01665	COG2310	stress, protein
KP952_RS01670	COG2310	stress, protein
KP952_RS01675	COG2310	stress, protein
KP952_RS01680	COG0861	Integral membrane protein TerC family
KP952_RS01690	COG3853	Toxic anion resistance protein (TelA)
KP952_RS01700	COG0477	Major facilitator Superfamily
KP952_RS01705	COG2814	Major facilitator Superfamily
KP952_RS01710	COG0640	Transcriptional regulator
KP952_RS01715	COG0517	IMP dehydrogenase activity
KP952_RS01715	COG4175	Glycine betaine
KP952_RS01720	COG4176	ABC-type proline glycine betaine transport system permease component
KP952_RS01725	COG2113	Glycine betaine
KP952_RS01730	COG1473	amidohydrolase
KP952_RS01735	COG1288	antiporter activity
KP952_RS01750	COG0039	L-malate dehydrogenase activity
KP952_RS01755	COG1620	l-lactate permease
KP952_RS01765	COG3403	YqcI/YcgG family
KP952_RS01780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KP952_RS01785	COG1660	Displays ATPase and GTPase activities
KP952_RS01790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KP952_RS01800	COG2226	methyltransferase
KP952_RS01805	COG0583	DNA-binding transcription factor activity
KP952_RS01810	COG3458	cephalosporin-C deacetylase activity
KP952_RS01815	COG3541	Predicted nucleotidyltransferase
KP952_RS01820	COG0506	proline dehydrogenase activity
KP952_RS01825	COG1012	belongs to the aldehyde dehydrogenase family
KP952_RS01830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KP952_RS01835	COG2508	Transcriptional regulator
KP952_RS01840	COG3689	TIGRFAM TIGR03943 family protein
KP952_RS01845	COG0701	Predicted permease
KP952_RS01850	COG2267	carboxylic ester hydrolase activity
KP952_RS01855	COG0492	ferredoxin-NADP+ reductase activity
KP952_RS01860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KP952_RS01860	COG1587	Uroporphyrinogen-III synthase
KP952_RS01865	COG2146	nitrite reductase [NAD(P)H] activity
KP952_RS01870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KP952_RS01875	COG0243	molybdopterin cofactor binding
KP952_RS01880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KP952_RS01885	COG2223	nitrite transmembrane transporter activity
KP952_RS01895	COG1376	ErfK ybiS ycfS ynhG family protein
KP952_RS01910	COG0765	amino acid transport
KP952_RS01915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KP952_RS01925	COG1714	RDD family
KP952_RS01935	COG1846	Transcriptional regulator
KP952_RS01950	COG2723	6-phospho-beta-galactosidase activity
KP952_RS01960	COG3209	COG3209 Rhs family protein
KP952_RS01970	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KP952_RS01975	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KP952_RS01980	COG1733	regulation of RNA biosynthetic process
KP952_RS01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KP952_RS01995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KP952_RS02000	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KP952_RS02005	COG2814	Major facilitator Superfamily
KP952_RS02015	COG0697	spore germination
KP952_RS02020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KP952_RS02030	COG2364	Membrane
KP952_RS02035	COG1126	abc transporter atp-binding protein
KP952_RS02040	COG0765	amino acid transport
KP952_RS02045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KP952_RS02050	COG0583	DNA-binding transcription factor activity
KP952_RS02055	COG0163	prenyltransferase activity
KP952_RS02060	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KP952_RS02075	COG0596	Alpha beta hydrolase
KP952_RS02080	COG3104	oligopeptide transport
KP952_RS02085	COG5434	Belongs to the glycosyl hydrolase 28 family
KP952_RS02095	COG0697	spore germination
KP952_RS02105	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KP952_RS02110	COG1136	(ABC) transporter
KP952_RS02115	COG0577	efflux transmembrane transporter activity
KP952_RS02120	COG0745	RESPONSE REGULATOR receiver
KP952_RS02125	COG3850	Histidine kinase
KP952_RS02125	COG5002	protein histidine kinase activity
KP952_RS02130	COG0457	Tetratricopeptide repeat
KP952_RS02150	COG0527	aspartate kinase activity
KP952_RS02155	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KP952_RS02160	COG4605	iron ion homeostasis
KP952_RS02165	COG4604	ABC transporter, ATP-binding protein
KP952_RS02170	COG4607	ABC-type enterochelin transport system periplasmic component
KP952_RS02180	COG2814	Major facilitator Superfamily
KP952_RS02185	COG1309	transcriptional regulator
KP952_RS02190	COG0778	Nitroreductase
KP952_RS02195	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KP952_RS02200	COG0640	Transcriptional regulator
KP952_RS02205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KP952_RS02210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KP952_RS02215	COG1012	belongs to the aldehyde dehydrogenase family
KP952_RS02220	COG4975	Glucose uptake
KP952_RS02225	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS02230	COG4549	nuclear export factor GLE1
KP952_RS02235	COG1276	copper resistance
KP952_RS02235	COG2372	response to copper ion
KP952_RS02240	COG1349	DNA-binding transcription factor activity
KP952_RS02250	COG2213	PTS system mannitol-specific
KP952_RS02255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KP952_RS02260	COG0246	Mannitol dehydrogenase
KP952_RS02265	COG0473	3-isopropylmalate dehydrogenase activity
KP952_RS02270	COG0681	Belongs to the peptidase S26 family
KP952_RS02280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KP952_RS02290	COG0561	phosphatase activity
KP952_RS02295	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KP952_RS02300	COG1914	H( )-stimulated, divalent metal cation uptake system
KP952_RS02305	COG4336	lyase activity
KP952_RS02310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KP952_RS02315	COG1984	allophanate hydrolase subunit 2
KP952_RS02320	COG1414	Transcriptional regulator
KP952_RS02325	COG2755	lipolytic protein G-D-S-L family
KP952_RS02335	COG2329	Antibiotic biosynthesis monooxygenase
KP952_RS02340	COG0768	penicillin binding
KP952_RS02345	COG4989	oxidoreductase activity
KP952_RS02350	COG3711	transcriptional antiterminator
KP952_RS02355	COG0318	PFAM AMP-dependent synthetase and ligase
KP952_RS02360	COG2226	methyltransferase
KP952_RS02365	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS02370	COG1917	Cupin 2, conserved barrel domain protein
KP952_RS02375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KP952_RS02380	COG3871	stress protein (general stress protein 26)
KP952_RS02390	COG2814	Major facilitator Superfamily
KP952_RS02395	COG1522	sequence-specific DNA binding
KP952_RS02400	COG0551	DNA topoisomerase type I activity
KP952_RS02400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KP952_RS02405	COG0494	nUDIX hydrolase
KP952_RS02410	COG0028	Belongs to the TPP enzyme family
KP952_RS02435	COG1914	H( )-stimulated, divalent metal cation uptake system
KP952_RS02440	COG2261	transglycosylase associated protein
KP952_RS02445	COG4876	unkown
KP952_RS02450	COG2217	Heavy metal translocating P-type atpase
KP952_RS02455	COG3729	General stress protein
KP952_RS02460	COG0662	Cupin 2, conserved barrel domain protein
KP952_RS02465	COG2329	Antibiotic biosynthesis monooxygenase
KP952_RS02470	COG3546	catalase activity
KP952_RS02475	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KP952_RS02480	COG3290	protein histidine kinase activity
KP952_RS02485	COG4565	transcriptional regulatory protein
KP952_RS02490	COG1301	dicarboxylic acid transport
KP952_RS02495	COG0628	permease
KP952_RS02500	COG1131	(ABC) transporter
KP952_RS02505	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KP952_RS02515	COG1960	acyl-CoA dehydrogenase activity
KP952_RS02530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KP952_RS02535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KP952_RS02540	COG1181	Belongs to the D-alanine--D-alanine ligase family
KP952_RS02545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KP952_RS02550	COG0513	Belongs to the DEAD box helicase family
KP952_RS02555	COG3402	PFAM membrane-flanked domain
KP952_RS02560	COG3428	Bacterial PH domain
KP952_RS02565	COG0705	Rhomboid family
KP952_RS02570	COG0736	holo-[acyl-carrier-protein] synthase activity
KP952_RS02575	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KP952_RS02580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KP952_RS02585	COG0864	Transcriptional regulator
KP952_RS02590	COG2337	Toxic component of a toxin-antitoxin (TA) module
KP952_RS02595	COG1366	Belongs to the anti-sigma-factor antagonist family
KP952_RS02600	COG1366	Belongs to the anti-sigma-factor antagonist family
KP952_RS02605	COG2172	sigma factor antagonist activity
KP952_RS02610	COG2208	phosphoserine phosphatase activity
KP952_RS02615	COG1366	Belongs to the anti-sigma-factor antagonist family
KP952_RS02620	COG2172	sigma factor antagonist activity
KP952_RS02625	COG1191	sigma factor activity
KP952_RS02630	COG2208	phosphoserine phosphatase activity
KP952_RS02645	COG1673	EVE domain
KP952_RS02650	COG1846	Transcriptional regulator
KP952_RS02655	COG2183	response to ionizing radiation
KP952_RS02665	COG3091	SprT-like family
KP952_RS02705	COG0582	viral genome integration into host DNA
KP952_RS02710	COG2856	Zn peptidase
KP952_RS02715	COG1396	sequence-specific DNA binding
KP952_RS02745	COG1674	ftsk spoiiie
KP952_RS02750	COG2946	Replication initiation factor
KP952_RS02790	COG0433	COG0433 Predicted ATPase
KP952_RS02800	COG5644	endopeptidase inhibitor activity
KP952_RS02810	COG0741	lytic transglycosylase activity
KP952_RS02810	COG0791	NLP P60 protein
KP952_RS02825	COG0457	Tetratricopeptide repeat
KP952_RS02855	COG0583	DNA-binding transcription factor activity
KP952_RS02860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KP952_RS02870	COG5444	nuclease activity
KP952_RS02875	COG1476	TRANSCRIPTIONal
KP952_RS02895	COG0693	protein deglycase activity
KP952_RS02900	COG1278	Cold shock
KP952_RS02905	COG1329	Transcriptional regulator
KP952_RS02910	COG0697	spore germination
KP952_RS02915	COG1917	Cupin 2, conserved barrel domain protein
KP952_RS02915	COG2207	Transcriptional regulator
KP952_RS02920	COG0697	spore germination
KP952_RS02925	COG3708	Transcriptional regulator
KP952_RS02925	COG2207	Transcriptional regulator
KP952_RS02930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KP952_RS02945	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
KP952_RS02955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KP952_RS02960	COG1309	transcriptional regulator
KP952_RS02965	COG0697	spore germination
KP952_RS02970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KP952_RS02975	COG2030	dehydratase
KP952_RS02980	COG3545	Serine hydrolase
KP952_RS02985	COG1733	regulation of RNA biosynthetic process
KP952_RS02990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KP952_RS02995	COG0640	Transcriptional regulator
KP952_RS03000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KP952_RS03010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KP952_RS03015	COG0697	spore germination
KP952_RS03020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KP952_RS03025	COG0076	glutamate decarboxylase activity
KP952_RS03030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KP952_RS03035	COG0640	Transcriptional regulator
KP952_RS03055	COG4585	Histidine kinase
KP952_RS03060	COG2197	response regulator
KP952_RS03065	COG2409	Drug exporters of the RND superfamily
KP952_RS03070	COG0596	Alpha beta hydrolase
KP952_RS03075	COG1811	Na channel or pump
KP952_RS03080	COG0789	Transcriptional regulator
KP952_RS03080	COG4978	Transcriptional regulator
KP952_RS03085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KP952_RS03090	COG0778	Nitroreductase
KP952_RS03095	COG0346	lactoylglutathione lyase activity
KP952_RS03100	COG2259	Doxx family
KP952_RS03105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KP952_RS03125	COG2323	membrane
KP952_RS03130	COG2323	membrane
KP952_RS03135	COG0071	Belongs to the small heat shock protein (HSP20) family
KP952_RS03150	COG1309	transcriptional regulator
KP952_RS03160	COG0456	acetyltransferase
KP952_RS03170	COG1113	amino acid transport
KP952_RS03175	COG2318	DinB family
KP952_RS03180	COG1846	Transcriptional regulator
KP952_RS03185	COG1033	growth of symbiont in host cell
KP952_RS03185	COG2409	Drug exporters of the RND superfamily
KP952_RS03190	COG0778	Nitroreductase
KP952_RS03195	COG1846	Transcriptional regulator
KP952_RS03200	COG2814	Major facilitator Superfamily
KP952_RS03205	COG0730	response to heat
KP952_RS03210	COG1802	Transcriptional regulator
KP952_RS03215	COG3858	chitin binding
KP952_RS03215	COG1388	LysM domain
KP952_RS03220	COG1819	glycosyl
KP952_RS03230	COG1785	Belongs to the alkaline phosphatase family
KP952_RS03235	COG5646	InterPro IPR014922
KP952_RS03245	COG0454	-acetyltransferase
KP952_RS03250	COG1078	dGTPase activity
KP952_RS03255	COG1388	LysM domain
KP952_RS03260	COG2814	Major facilitator Superfamily
KP952_RS03265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KP952_RS03280	COG2723	6-phospho-beta-galactosidase activity
KP952_RS03285	COG2188	Transcriptional regulator
KP952_RS03290	COG1940	carbohydrate kinase activity
KP952_RS03300	COG4124	Belongs to the glycosyl hydrolase 26 family
KP952_RS03345	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KP952_RS03350	COG0802	atpase or kinase
KP952_RS03355	COG1214	PFAM Peptidase M22, glycoprotease
KP952_RS03360	COG0456	acetyltransferase
KP952_RS03365	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KP952_RS03370	COG0488	(ABC) transporter
KP952_RS03375	COG0315	cyclic pyranopterin monophosphate synthase activity
KP952_RS03380	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KP952_RS03385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KP952_RS03390	COG0805	protein transport
KP952_RS03400	COG1266	CAAX protease self-immunity
KP952_RS03410	COG0459	protein refolding
KP952_RS03425	COG0457	Tetratricopeptide repeat
KP952_RS03430	COG1063	alcohol dehydrogenase
KP952_RS03435	COG2211	Major facilitator Superfamily
KP952_RS03440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KP952_RS03445	COG1842	Phage shock protein A
KP952_RS03450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KP952_RS03455	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KP952_RS03460	COG4260	virion core protein, lumpy skin disease virus
KP952_RS03470	COG2814	Major facilitator Superfamily
KP952_RS03475	COG1063	alcohol dehydrogenase
KP952_RS03480	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KP952_RS03485	COG0823	Involved in the tonB-independent uptake of proteins
KP952_RS03505	COG2267	carboxylic ester hydrolase activity
KP952_RS03515	COG2132	Multicopper oxidase
KP952_RS03520	COG1113	amino acid transport
KP952_RS03530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KP952_RS03535	COG0714	Associated with various cellular activities
KP952_RS03540	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KP952_RS03545	COG1305	Transglutaminase-like
KP952_RS03550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KP952_RS03550	COG0519	Catalyzes the synthesis of GMP from XMP
KP952_RS03560	COG2252	PERMEase
KP952_RS03565	COG3064	Membrane
KP952_RS03575	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
KP952_RS03585	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KP952_RS03590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KP952_RS03595	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KP952_RS03600	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KP952_RS03605	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KP952_RS03610	COG0047	phosphoribosylformylglycinamidine synthase activity
KP952_RS03615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KP952_RS03620	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KP952_RS03625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KP952_RS03630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KP952_RS03635	COG0138	bifunctional purine biosynthesis protein purh
KP952_RS03640	COG0151	Belongs to the GarS family
KP952_RS03645	COG1522	sequence-specific DNA binding
KP952_RS03660	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KP952_RS03665	COG1470	cell adhesion involved in biofilm formation
KP952_RS03670	COG4496	protein, YerC YecD
KP952_RS03675	COG0069	glutamate synthase activity
KP952_RS03680	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KP952_RS03685	COG0210	DNA helicase
KP952_RS03690	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KP952_RS03695	COG4851	CamS sex pheromone cAM373 precursor
KP952_RS03705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KP952_RS03710	COG1285	pathogenesis
KP952_RS03715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KP952_RS03720	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KP952_RS03725	COG0154	amidase activity
KP952_RS03730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KP952_RS03740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KP952_RS03745	COG1597	lipid kinase activity
KP952_RS03750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KP952_RS03755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KP952_RS03780	COG5444	nuclease activity
KP952_RS03790	COG0457	Tetratricopeptide repeat
KP952_RS03800	COG0217	transcriptional regulatory protein
KP952_RS03810	COG1309	transcriptional regulator
KP952_RS03825	COG3546	catalase activity
KP952_RS03830	COG0454	-acetyltransferase
KP952_RS03840	COG5578	integral membrane protein
KP952_RS03845	COG2972	Histidine kinase
KP952_RS03855	COG1653	transport
KP952_RS03860	COG1175	transmembrane transport
KP952_RS03865	COG0395	ABC-type sugar transport system, permease component
KP952_RS03870	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KP952_RS03875	COG2207	Transcriptional regulator
KP952_RS03880	COG2755	lipolytic protein G-D-S-L family
KP952_RS03890	COG5578	integral membrane protein
KP952_RS03895	COG3401	FG-GAP repeat protein
KP952_RS03900	COG3401	FG-GAP repeat protein
KP952_RS03905	COG2755	lipolytic protein G-D-S-L family
KP952_RS03920	COG1653	transport
KP952_RS03925	COG4209	transmembrane transport
KP952_RS03930	COG0395	ABC-type sugar transport system, permease component
KP952_RS03935	COG1486	melibiose metabolic process
KP952_RS03940	COG2323	membrane
KP952_RS03945	COG2329	Antibiotic biosynthesis monooxygenase
KP952_RS03950	COG0346	lactoylglutathione lyase activity
KP952_RS03965	COG5583	Uncharacterized small protein (DUF2292)
KP952_RS03970	COG0670	Belongs to the BI1 family
KP952_RS03985	COG3328	transposase activity
KP952_RS03995	COG2124	cytochrome p450
KP952_RS03995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KP952_RS04000	COG1368	sulfuric ester hydrolase activity
KP952_RS04005	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KP952_RS04010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KP952_RS04015	COG1442	glycosyl transferase family 8
KP952_RS04020	COG1216	Glycosyl transferase, family 2
KP952_RS04025	COG1442	glycosyl transferase family 8
KP952_RS04030	COG2223	nitrite transmembrane transporter activity
KP952_RS04035	COG1011	Hydrolase
KP952_RS04040	COG0531	amino acid
KP952_RS04045	COG1012	belongs to the aldehyde dehydrogenase family
KP952_RS04050	COG0840	transmembrane signaling receptor activity
KP952_RS04055	COG0488	(ABC) transporter
KP952_RS04065	COG0789	Transcriptional regulator
KP952_RS04070	COG2814	Major facilitator Superfamily
KP952_RS04085	COG0488	(ABC) transporter
KP952_RS04090	COG0513	Belongs to the DEAD box helicase family
KP952_RS04100	COG3866	Pectate lyase
KP952_RS04105	COG0471	metal ion transport
KP952_RS04110	COG3290	protein histidine kinase activity
KP952_RS04115	COG4565	transcriptional regulatory protein
KP952_RS04120	COG3181	Tripartite tricarboxylate transporter family receptor
KP952_RS04125	COG2851	Citrate transporter
KP952_RS04130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KP952_RS04135	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KP952_RS04140	COG1254	Belongs to the acylphosphatase family
KP952_RS04145	COG2258	MOSC domain
KP952_RS04165	COG0024	Methionine aminopeptidase
KP952_RS04170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KP952_RS04170	COG1263	PTS System
KP952_RS04175	COG1368	sulfuric ester hydrolase activity
KP952_RS04190	COG1115	amino acid carrier protein
KP952_RS04210	COG1263	PTS System
KP952_RS04210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KP952_RS04215	COG0366	Alpha amylase catalytic
KP952_RS04220	COG2188	Transcriptional regulator
KP952_RS04225	COG0778	Nitroreductase
KP952_RS04230	COG0737	Belongs to the 5'-nucleotidase family
KP952_RS04235	COG0693	protein deglycase activity
KP952_RS04245	COG2814	Major facilitator Superfamily
KP952_RS04250	COG4840	Belongs to the UPF0435 family
KP952_RS04255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KP952_RS04260	COG4980	gas vesicle protein
KP952_RS04265	COG1295	ribonuclease BN
KP952_RS04270	COG0477	Major facilitator Superfamily
KP952_RS04275	COG0387	Pfam Sodium calcium exchanger
KP952_RS04285	COG0668	transmembrane transport
KP952_RS04290	COG0535	radical SAM domain protein
KP952_RS04300	COG0726	polysaccharide deacetylase
KP952_RS04305	COG2084	Dehydrogenase
KP952_RS04310	COG0598	Magnesium transport protein CorA
KP952_RS04315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KP952_RS04320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KP952_RS04330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KP952_RS04335	COG4637	Psort location Cytoplasmic, score
KP952_RS04345	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KP952_RS04350	COG0022	dehydrogenase e1 component
KP952_RS04355	COG0508	dehydrogenase complex catalyzes the overall conversion of
KP952_RS04360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KP952_RS04365	COG3284	Transcriptional regulator
KP952_RS04375	COG1742	UPF0060 membrane protein
KP952_RS04400	COG4842	Belongs to the WXG100 family
KP952_RS04405	COG1486	melibiose metabolic process
KP952_RS04410	COG1737	Transcriptional regulator
KP952_RS04415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KP952_RS04415	COG1263	PTS System
KP952_RS04420	COG5434	Belongs to the glycosyl hydrolase 28 family
KP952_RS04425	COG1132	(ABC) transporter
KP952_RS04430	COG1132	(ABC) transporter
KP952_RS04435	COG2259	Doxx family
KP952_RS04440	COG2514	catechol 2,3-dioxygenase activity
KP952_RS04445	COG1917	Cupin 2, conserved barrel domain protein
KP952_RS04445	COG4977	sequence-specific DNA binding
KP952_RS04450	COG2814	Major facilitator Superfamily
KP952_RS04455	COG1082	Xylose isomerase domain protein TIM barrel
KP952_RS04465	COG4585	Histidine kinase
KP952_RS04470	COG2197	response regulator
KP952_RS04475	COG1131	(ABC) transporter
KP952_RS04480	COG0842	Transport permease protein
KP952_RS04480	COG1511	domain protein
KP952_RS04485	COG0842	Transport permease protein
KP952_RS04490	COG1695	Transcriptional regulator
KP952_RS04495	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KP952_RS04505	COG1309	transcriptional regulator
KP952_RS04510	COG2814	Major facilitator Superfamily
KP952_RS04515	COG2318	DinB family
KP952_RS04520	COG2814	Major facilitator Superfamily
KP952_RS04525	COG1846	Transcriptional regulator
KP952_RS04530	COG0392	lysyltransferase activity
KP952_RS04530	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KP952_RS04535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KP952_RS04540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KP952_RS04545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KP952_RS04550	COG0384	phenazine biosynthesis protein PhzF
KP952_RS04555	COG0778	Nitroreductase
KP952_RS04570	COG1090	epimerase
KP952_RS04575	COG2137	regulation of response to DNA damage stimulus
KP952_RS04585	COG2814	Major facilitator Superfamily
KP952_RS04600	COG3103	Sh3 type 3 domain protein
KP952_RS04605	COG5658	integral membrane protein
KP952_RS04610	COG0596	Alpha beta hydrolase
KP952_RS04615	COG0463	Glycosyl transferase, family 2
KP952_RS04620	COG4485	Bacterial membrane protein, YfhO
KP952_RS04625	COG1988	membrane-bound metal-dependent
KP952_RS04630	COG1194	a g-specific adenine glycosylase
KP952_RS04640	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS04655	COG3557	Belongs to the UPF0374 family
KP952_RS04660	COG1132	(ABC) transporter
KP952_RS04665	COG4129	membrane
KP952_RS04670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KP952_RS04675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KP952_RS04680	COG0735	belongs to the Fur family
KP952_RS04790	COG4326	sporulation control protein
KP952_RS04800	COG5577	PFAM Coat F domain
KP952_RS04805	COG3340	Belongs to the peptidase S51 family
KP952_RS04810	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KP952_RS04825	COG0753	catalase activity
KP952_RS04830	COG1116	anion transmembrane transporter activity
KP952_RS04835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KP952_RS04840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KP952_RS04845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KP952_RS04855	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KP952_RS04865	COG1476	TRANSCRIPTIONal
KP952_RS04875	COG3382	B3 4 domain protein
KP952_RS04880	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KP952_RS04890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KP952_RS04895	COG0789	Transcriptional regulator
KP952_RS04900	COG1664	Polymer-forming cytoskeletal
KP952_RS04905	COG1664	Polymer-forming cytoskeletal
KP952_RS04910	COG2766	serine protein kinase
KP952_RS04915	COG2718	Belongs to the UPF0229 family
KP952_RS04920	COG1846	Transcriptional regulator
KP952_RS04925	COG1566	PFAM secretion protein HlyD family protein
KP952_RS04930	COG2814	Major facilitator Superfamily
KP952_RS04935	COG0655	NAD(P)H dehydrogenase (quinone) activity
KP952_RS04955	COG1725	Transcriptional regulator
KP952_RS04960	COG1131	(ABC) transporter
KP952_RS04965	COG1131	(ABC) transporter
KP952_RS04970	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KP952_RS04975	COG1278	Cold shock
KP952_RS04980	COG1464	Belongs to the NlpA lipoprotein family
KP952_RS04985	COG3706	GGDEF domain
KP952_RS04990	COG1823	symporter activity
KP952_RS04995	COG5444	nuclease activity
KP952_RS05020	COG0582	viral genome integration into host DNA
KP952_RS05080	COG5644	endopeptidase inhibitor activity
KP952_RS05085	COG0741	lytic transglycosylase activity
KP952_RS05085	COG0791	NLP P60 protein
KP952_RS05105	COG0457	Tetratricopeptide repeat
KP952_RS05135	COG0737	Belongs to the 5'-nucleotidase family
KP952_RS05135	COG4085	toxin activity
KP952_RS05135	COG1525	nuclease
KP952_RS05140	COG3764	Sortase (surface protein transpeptidase)
KP952_RS05145	COG0564	pseudouridine synthase activity
KP952_RS05155	COG0517	IMP dehydrogenase activity
KP952_RS05160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KP952_RS05165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KP952_RS05165	COG3153	acetyltransferase
KP952_RS05170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KP952_RS05175	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KP952_RS05180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KP952_RS05185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KP952_RS05190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KP952_RS05195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KP952_RS05200	COG2203	Gaf domain
KP952_RS05200	COG4585	Histidine kinase
KP952_RS05205	COG2197	response regulator
KP952_RS05210	COG0431	NADPH-dependent FMN reductase
KP952_RS05225	COG0791	NLP P60 protein
KP952_RS05225	COG1388	LysM domain
KP952_RS05230	COG1959	2 iron, 2 sulfur cluster binding
KP952_RS05235	COG0668	transmembrane transport
KP952_RS05240	COG2719	SpoVR family
KP952_RS05245	COG1785	Belongs to the alkaline phosphatase family
KP952_RS05250	COG0791	NLP P60 protein
KP952_RS05250	COG1388	LysM domain
KP952_RS05255	COG0583	DNA-binding transcription factor activity
KP952_RS05260	COG0372	Belongs to the citrate synthase family
KP952_RS05265	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS05270	COG0531	amino acid
KP952_RS05275	COG0733	neurotransmitter:sodium symporter activity
KP952_RS05280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KP952_RS05285	COG0456	acetyltransferase
KP952_RS05300	COG1595	DNA-templated transcription, initiation
KP952_RS05305	COG0667	Aldo Keto reductase
KP952_RS05310	COG0204	Acyl-transferase
KP952_RS05315	COG1253	flavin adenine dinucleotide binding
KP952_RS05320	COG0789	Transcriptional regulator
KP952_RS05330	COG1253	flavin adenine dinucleotide binding
KP952_RS05335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KP952_RS05340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KP952_RS05345	COG0584	glycerophosphoryl diester phosphodiesterase
KP952_RS05355	COG0668	transmembrane transport
KP952_RS05360	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KP952_RS05365	COG0726	polysaccharide deacetylase
KP952_RS05370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KP952_RS05375	COG1757	Na H antiporter
KP952_RS05380	COG0589	response to stress
KP952_RS05390	COG1132	(ABC) transporter
KP952_RS05395	COG1132	(ABC) transporter
KP952_RS05400	COG0702	epimerase
KP952_RS05425	COG0189	ligase activity
KP952_RS05430	COG0189	ligase activity
KP952_RS05435	COG4399	Belongs to the UPF0754 family
KP952_RS05440	COG3679	Belongs to the UPF0342 family
KP952_RS05450	COG0561	phosphatase activity
KP952_RS05455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KP952_RS05460	COG0475	glutathione-regulated potassium exporter activity
KP952_RS05465	COG0490	domain, Protein
KP952_RS05475	COG1024	Enoyl-CoA hydratase
KP952_RS05485	COG4152	abc transporter atp-binding protein
KP952_RS05490	COG1668	transmembrane transport
KP952_RS05495	COG0420	3'-5' exonuclease activity
KP952_RS05500	COG4717	serine-type aminopeptidase activity
KP952_RS05505	COG3481	metal-dependent phosphohydrolase, HD sub domain
KP952_RS05515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KP952_RS05545	COG1846	Transcriptional regulator
KP952_RS05550	COG4980	gas vesicle protein
KP952_RS05565	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KP952_RS05570	COG0537	adenosine 5'-monophosphoramidase activity
KP952_RS05575	COG1131	(ABC) transporter
KP952_RS05580	COG4473	ABC transporter
KP952_RS05590	COG1473	amidohydrolase
KP952_RS05595	COG3069	C4-dicarboxylate transmembrane transporter activity
KP952_RS05605	COG2329	Antibiotic biosynthesis monooxygenase
KP952_RS05610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KP952_RS05615	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KP952_RS05620	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KP952_RS05625	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KP952_RS05630	COG1309	transcriptional regulator
KP952_RS05635	COG1511	domain protein
KP952_RS05640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KP952_RS05645	COG4377	Putative membrane peptidase family (DUF2324)
KP952_RS05655	COG1363	Peptidase, m42
KP952_RS05660	COG4405	Protein conserved in bacteria
KP952_RS05665	COG1301	dicarboxylic acid transport
KP952_RS05675	COG1234	tRNA 3'-trailer cleavage
KP952_RS05680	COG0095	Lipoate-protein ligase
KP952_RS05685	COG0702	epimerase
KP952_RS05690	COG0318	PFAM AMP-dependent synthetase and ligase
KP952_RS05700	COG0501	Belongs to the peptidase M48B family
KP952_RS05710	COG0456	acetyltransferase
KP952_RS05715	COG0604	alcohol dehydrogenase
KP952_RS05720	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KP952_RS05725	COG0406	alpha-ribazole phosphatase activity
KP952_RS05730	COG0183	Belongs to the thiolase family
KP952_RS05735	COG0318	PFAM AMP-dependent synthetase and ligase
KP952_RS05740	COG1268	BioY protein
KP952_RS05745	COG0840	transmembrane signaling receptor activity
KP952_RS05755	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS05765	COG4903	ComK protein
KP952_RS05770	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS05780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KP952_RS05795	COG0398	Pfam SNARE associated Golgi protein
KP952_RS05800	COG0681	Belongs to the peptidase S26 family
KP952_RS05805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KP952_RS05810	COG1846	Transcriptional regulator
KP952_RS05825	COG0738	Major facilitator superfamily
KP952_RS05830	COG0673	inositol 2-dehydrogenase activity
KP952_RS05835	COG0561	phosphatase activity
KP952_RS05840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KP952_RS05845	COG1609	Transcriptional regulator
KP952_RS05850	COG3180	Ammonia monooxygenase
KP952_RS05855	COG2814	Major facilitator Superfamily
KP952_RS05855	COG0477	Major facilitator Superfamily
KP952_RS05860	COG4533	DNA binding
KP952_RS05875	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KP952_RS05880	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KP952_RS05885	COG1074	ATP-dependent DNA helicase activity
KP952_RS05890	COG0420	3'-5' exonuclease activity
KP952_RS05895	COG0419	ATPase involved in DNA repair
KP952_RS05900	COG1403	HNH endonuclease
KP952_RS05940	COG5337	Spore coat protein CotH
KP952_RS05945	COG0179	Fumarylacetoacetate (FAA) hydrolase
KP952_RS05955	COG1404	Belongs to the peptidase S8 family
KP952_RS05965	COG0367	asparagine synthase
KP952_RS05975	COG0534	Mate efflux family protein
KP952_RS05980	COG2207	Transcriptional regulator
KP952_RS05980	COG1917	Cupin 2, conserved barrel domain protein
KP952_RS05985	COG1609	Transcriptional regulator
KP952_RS05990	COG0673	inositol 2-dehydrogenase activity
KP952_RS05995	COG2318	DinB family
KP952_RS06000	COG1279	arginine transmembrane transporter activity
KP952_RS06005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KP952_RS06010	COG1357	PFAM Pentapeptide repeats (8 copies)
KP952_RS06015	COG2267	carboxylic ester hydrolase activity
KP952_RS06025	COG2153	protein acetylation
KP952_RS06030	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KP952_RS06030	COG0646	methionine synthase
KP952_RS06035	COG1666	GTP binding
KP952_RS06040	COG2996	Protein conserved in bacteria
KP952_RS06050	COG1307	EDD domain protein, DegV family
KP952_RS06055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KP952_RS06075	COG0561	phosphatase activity
KP952_RS06080	COG1073	alpha beta
KP952_RS06085	COG2151	metal-sulfur cluster biosynthetic enzyme
KP952_RS06095	COG0277	FAD linked oxidase domain protein
KP952_RS06105	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KP952_RS06110	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KP952_RS06120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KP952_RS06125	COG0505	Belongs to the CarA family
KP952_RS06130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KP952_RS06135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KP952_RS06155	COG2267	carboxylic ester hydrolase activity
KP952_RS06165	COG1744	ABC transporter substrate-binding protein PnrA-like
KP952_RS06180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KP952_RS06185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KP952_RS06190	COG5504	Zn-dependent protease
KP952_RS06195	COG0444	Belongs to the ABC transporter superfamily
KP952_RS06200	COG4608	Belongs to the ABC transporter superfamily
KP952_RS06210	COG0601	transmembrane transport
KP952_RS06215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KP952_RS06225	COG0180	Tryptophanyl-tRNA synthetase
KP952_RS06230	COG4166	transmembrane transport
KP952_RS06235	COG0601	transmembrane transport
KP952_RS06240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KP952_RS06245	COG0444	Belongs to the ABC transporter superfamily
KP952_RS06250	COG4608	Belongs to the ABC transporter superfamily
KP952_RS06255	COG2814	Major facilitator Superfamily
KP952_RS06260	COG0456	acetyltransferase
KP952_RS06265	COG1393	Belongs to the ArsC family
KP952_RS06270	COG0861	Integral membrane protein TerC family
KP952_RS06280	COG4862	establishment of competence for transformation
KP952_RS06290	COG4469	Competence protein
KP952_RS06295	COG1164	Oligoendopeptidase f
KP952_RS06305	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KP952_RS06310	COG2346	COG2346, Truncated hemoglobins
KP952_RS06315	COG0741	lytic transglycosylase activity
KP952_RS06320	COG4116	CYTH
KP952_RS06330	COG2357	RelA SpoT domain protein
KP952_RS06335	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KP952_RS06340	COG0564	pseudouridine synthase activity
KP952_RS06345	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KP952_RS06350	COG0475	glutathione-regulated potassium exporter activity
KP952_RS06350	COG0569	domain protein
KP952_RS06355	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KP952_RS06360	COG0352	thiamine-phosphate diphosphorylase activity
KP952_RS06365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KP952_RS06370	COG2104	thiamine diphosphate biosynthetic process
KP952_RS06375	COG2022	thiamine diphosphate biosynthetic process
KP952_RS06380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KP952_RS06385	COG0351	phosphomethylpyrimidine kinase
KP952_RS06390	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KP952_RS06445	COG0210	DNA helicase
KP952_RS06455	COG2153	protein acetylation
KP952_RS06460	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KP952_RS06465	COG2382	esterase
KP952_RS06470	COG0626	cystathionine gamma-synthase activity
KP952_RS06475	COG0626	cystathionine gamma-synthase activity
KP952_RS06480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KP952_RS06485	COG5505	Protein of unknown function (DUF819)
KP952_RS06515	COG1396	sequence-specific DNA binding
KP952_RS06585	COG0457	Tetratricopeptide repeat
KP952_RS06590	COG5444	nuclease activity
KP952_RS06600	COG3328	transposase activity
KP952_RS06650	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KP952_RS06660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KP952_RS06660	COG3711	transcriptional antiterminator
KP952_RS06665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KP952_RS06665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KP952_RS06665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KP952_RS06670	COG1482	cell wall glycoprotein biosynthetic process
KP952_RS06685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KP952_RS06695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KP952_RS06710	COG0109	protoheme IX farnesyltransferase activity
KP952_RS06720	COG0726	polysaccharide deacetylase
KP952_RS06740	COG2205	protein histidine kinase activity
KP952_RS06750	COG3383	formate dehydrogenase (NAD+) activity
KP952_RS06755	COG2427	Protein of unknown function (DUF1641)
KP952_RS06765	COG1051	belongs to the nudix hydrolase family
KP952_RS06775	COG2124	cytochrome p450
KP952_RS06780	COG1819	glycosyl
KP952_RS06790	COG1587	Uroporphyrinogen-III synthase
KP952_RS06795	COG0390	transport system, permease component
KP952_RS06800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KP952_RS06805	COG0697	spore germination
KP952_RS06820	COG1252	NADH dehydrogenase
KP952_RS06825	COG1904	glucuronate isomerase
KP952_RS06835	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KP952_RS06840	COG1063	alcohol dehydrogenase
KP952_RS06845	COG1312	Catalyzes the dehydration of D-mannonate
KP952_RS06850	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS06855	COG2271	Major facilitator Superfamily
KP952_RS06860	COG1609	Transcriptional regulator
KP952_RS06865	COG0246	Mannitol dehydrogenase
KP952_RS06870	COG2721	sulfolactate sulfo-lyase activity
KP952_RS06875	COG0730	response to heat
KP952_RS06880	COG2318	DinB family
KP952_RS06900	COG0457	Tetratricopeptide repeat
KP952_RS06915	COG1388	LysM domain
KP952_RS06915	COG3409	Peptidoglycan-binding domain 1 protein
KP952_RS06915	COG5632	N-Acetylmuramoyl-L-alanine amidase
KP952_RS06925	COG4195	phage-related replication protein
KP952_RS06930	COG3546	catalase activity
KP952_RS06935	COG2856	Zn peptidase
KP952_RS06940	COG1396	sequence-specific DNA binding
KP952_RS06950	COG1522	sequence-specific DNA binding
KP952_RS06955	COG1484	DNA-dependent DNA replication
KP952_RS06975	COG1595	DNA-templated transcription, initiation
KP952_RS06980	COG5484	DNA packaging
KP952_RS06980	COG3728	DNA packaging
KP952_RS06985	COG1783	phage Terminase large subunit
KP952_RS06990	COG5518	Phage portal protein
KP952_RS06995	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KP952_RS07000	COG4653	Phage capsid family
KP952_RS07050	COG5412	phage tail tape measure protein
KP952_RS07050	COG3953	SLT domain
KP952_RS07050	COG5412	phage tail tape measure protein
KP952_RS07050	COG3953	SLT domain
KP952_RS07050	COG5412	phage tail tape measure protein
KP952_RS07050	COG3953	SLT domain
KP952_RS07055	COG1652	LysM domain
KP952_RS07060	COG4193	domain, Protein
KP952_RS07070	COG3628	GPW Gp25 family protein
KP952_RS07075	COG3299	homolog of phage Mu protein gp47
KP952_RS07080	COG3778	Protein conserved in bacteria
KP952_RS07120	COG3409	Peptidoglycan-binding domain 1 protein
KP952_RS07120	COG5632	N-Acetylmuramoyl-L-alanine amidase
KP952_RS07140	COG0306	phosphate transporter
KP952_RS07145	COG1392	Phosphate transport regulator
KP952_RS07150	COG0531	amino acid
KP952_RS07155	COG0346	lactoylglutathione lyase activity
KP952_RS07160	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KP952_RS07165	COG0463	Glycosyl transferase, family 2
KP952_RS07170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KP952_RS07175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KP952_RS07180	COG2362	D-Aminopeptidase
KP952_RS07185	COG0601	transmembrane transport
KP952_RS07190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KP952_RS07195	COG0444	Belongs to the ABC transporter superfamily
KP952_RS07200	COG4166	transmembrane transport
KP952_RS07205	COG1619	proteins homologs of microcin C7 resistance protein MccF
KP952_RS07210	COG4948	Mandelate Racemase Muconate Lactonizing
KP952_RS07215	COG0791	NLP P60 protein
KP952_RS07220	COG4608	Belongs to the ABC transporter superfamily
KP952_RS07225	COG2706	6-phosphogluconolactonase activity
KP952_RS07235	COG1607	acyl-coa hydrolase
KP952_RS07240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KP952_RS07240	COG1017	nitric oxide dioxygenase activity
KP952_RS07250	COG2323	membrane
KP952_RS07255	COG2318	DinB family
KP952_RS07260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KP952_RS07265	COG2076	Multidrug Resistance protein
KP952_RS07270	COG2076	Multidrug Resistance protein
KP952_RS07275	COG0788	formyltetrahydrofolate deformylase activity
KP952_RS07280	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KP952_RS07285	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KP952_RS07290	COG1764	response to oxidative stress
KP952_RS07295	COG1846	Transcriptional regulator
KP952_RS07300	COG1764	response to oxidative stress
KP952_RS07310	COG0590	tRNA wobble adenosine to inosine editing
KP952_RS07315	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KP952_RS07320	COG1404	Belongs to the peptidase S8 family
KP952_RS07325	COG1366	Belongs to the anti-sigma-factor antagonist family
KP952_RS07330	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KP952_RS07335	COG1122	ATPase activity
KP952_RS07350	COG0745	RESPONSE REGULATOR receiver
KP952_RS07355	COG3850	Histidine kinase
KP952_RS07355	COG5002	protein histidine kinase activity
KP952_RS07360	COG3212	peptidase
KP952_RS07365	COG3212	peptidase
KP952_RS07375	COG2239	Acts as a magnesium transporter
KP952_RS07380	COG0789	Transcriptional regulator
KP952_RS07395	COG1846	Transcriptional regulator
KP952_RS07400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KP952_RS07405	COG0726	polysaccharide deacetylase
KP952_RS07410	COG1408	metallophosphoesterase
KP952_RS07420	COG0463	Glycosyl transferase, family 2
KP952_RS07425	COG3285	dna ligase
KP952_RS07425	COG1793	dna ligase
KP952_RS07430	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KP952_RS07435	COG3300	MHYT domain
KP952_RS07435	COG5001	Diguanylate cyclase
KP952_RS07440	COG0586	Pfam SNARE associated Golgi protein
KP952_RS07445	COG0861	Integral membrane protein TerC family
KP952_RS07450	COG1191	sigma factor activity
KP952_RS07470	COG0501	Belongs to the peptidase M48B family
KP952_RS07475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KP952_RS07495	COG3594	Acyltransferase
KP952_RS07500	COG5002	protein histidine kinase activity
KP952_RS07505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KP952_RS07515	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KP952_RS07520	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KP952_RS07525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KP952_RS07530	COG0436	Aminotransferase
KP952_RS07535	COG1850	ribulose-bisphosphate carboxylase activity
KP952_RS07540	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KP952_RS07545	COG0235	Class ii aldolase
KP952_RS07550	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KP952_RS07555	COG3339	Conserved Protein
KP952_RS07570	COG3852	Histidine kinase
KP952_RS07575	COG1846	Transcriptional regulator
KP952_RS07580	COG1360	Flagellar Motor Protein
KP952_RS07585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KP952_RS07590	COG0542	response to heat
KP952_RS07595	COG3949	Membrane
KP952_RS07600	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KP952_RS07605	COG0720	synthase
KP952_RS07610	COG0602	queuosine metabolic process
KP952_RS07615	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KP952_RS07625	COG4873	Protein conserved in bacteria
KP952_RS07635	COG3773	Cell wall hydrolase
KP952_RS07640	COG2244	polysaccharide biosynthetic process
KP952_RS07645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KP952_RS07650	COG2217	Heavy metal translocating P-type atpase
KP952_RS07660	COG0006	proline dipeptidase activity
KP952_RS07665	COG1609	Transcriptional regulator
KP952_RS07670	COG3711	transcriptional antiterminator
KP952_RS07675	COG1263	PTS System
KP952_RS07675	COG2190	(PTS) system
KP952_RS07675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KP952_RS07680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KP952_RS07685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KP952_RS07695	COG1533	DNA photolyase activity
KP952_RS07700	COG0456	acetyltransferase
KP952_RS07705	COG0840	transmembrane signaling receptor activity
KP952_RS07710	COG2084	Dehydrogenase
KP952_RS07715	COG3328	transposase activity
KP952_RS07725	COG0768	penicillin binding
KP952_RS07730	COG4191	Histidine kinase
KP952_RS07735	COG0436	Aminotransferase
KP952_RS07745	COG0784	Response regulator, receiver
KP952_RS07745	COG0835	chemotaxis
KP952_RS07755	COG2814	Major facilitator Superfamily
KP952_RS07760	COG1376	ErfK ybiS ycfS ynhG family protein
KP952_RS07765	COG1408	metallophosphoesterase
KP952_RS07770	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS07775	COG2200	EAL domain
KP952_RS07780	COG4703	Protein of unknown function (DUF1797)
KP952_RS07785	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KP952_RS07795	COG0517	IMP dehydrogenase activity
KP952_RS07800	COG0583	DNA-binding transcription factor activity
KP952_RS07805	COG0716	FMN binding
KP952_RS07815	COG0716	FMN binding
KP952_RS07820	COG2171	N-acyltransferase activity
KP952_RS07825	COG1473	amidohydrolase
KP952_RS07835	COG0668	transmembrane transport
KP952_RS07840	COG0450	alkyl hydroperoxide reductase
KP952_RS07845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KP952_RS07865	COG0746	molybdenum cofactor guanylyltransferase activity
KP952_RS07870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KP952_RS07875	COG0303	'Molybdopterin
KP952_RS07880	COG1763	Mo-molybdopterin cofactor biosynthetic process
KP952_RS07885	COG0314	molybdopterin synthase activity
KP952_RS07890	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KP952_RS07895	COG1132	(ABC) transporter
KP952_RS07900	COG1132	(ABC) transporter
KP952_RS07910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KP952_RS07915	COG1136	(ABC) transporter
KP952_RS07920	COG0577	efflux transmembrane transporter activity
KP952_RS07925	COG1349	DNA-binding transcription factor activity
KP952_RS07930	COG1105	Belongs to the carbohydrate kinase PfkB family
KP952_RS07935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KP952_RS07935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KP952_RS07935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KP952_RS07940	COG0681	Belongs to the peptidase S26 family
KP952_RS07950	COG0488	(ABC) transporter
KP952_RS07955	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KP952_RS07960	COG2309	aminopeptidase activity
KP952_RS07970	COG1077	Cell shape determining protein MreB Mrl
KP952_RS07975	COG2002	toxin-antitoxin pair type II binding
KP952_RS07980	COG3852	Histidine kinase
KP952_RS07985	COG2105	PFAM AIG2 family protein
KP952_RS07985	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KP952_RS07990	COG0569	domain protein
KP952_RS07995	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KP952_RS08000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KP952_RS08005	COG5503	Protein of unknown function (DUF1447)
KP952_RS08010	COG0561	phosphatase activity
KP952_RS08015	COG0242	peptide deformylase activity
KP952_RS08025	COG0497	DNA recombination
KP952_RS08030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KP952_RS08035	COG0022	dehydrogenase e1 component
KP952_RS08040	COG0508	dehydrogenase complex catalyzes the overall conversion of
KP952_RS08045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KP952_RS08050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KP952_RS08060	COG1982	Orn Lys Arg decarboxylase major
KP952_RS08065	COG4476	Belongs to the UPF0223 family
KP952_RS08070	COG4493	Belongs to the UPF0637 family
KP952_RS08080	COG0483	inositol monophosphate 1-phosphatase activity
KP952_RS08095	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KP952_RS08135	COG1217	gtp-binding protein TYPA
KP952_RS08145	COG4896	Protein conserved in bacteria
KP952_RS08155	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KP952_RS08160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KP952_RS08165	COG2066	Belongs to the glutaminase family
KP952_RS08170	COG4838	Belongs to the UPF0358 family
KP952_RS08175	COG0772	Belongs to the SEDS family
KP952_RS08180	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KP952_RS08185	COG1612	heme a metabolic process
KP952_RS08190	COG0109	protoheme IX farnesyltransferase activity
KP952_RS08195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KP952_RS08195	COG2010	Cytochrome c
KP952_RS08200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KP952_RS08205	COG1845	cytochrome c oxidase, subunit III
KP952_RS08210	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KP952_RS08215	COG3336	cytochrome c oxidase
KP952_RS08225	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KP952_RS08230	COG2340	Cysteine-rich secretory protein family
KP952_RS08245	COG3679	Belongs to the UPF0342 family
KP952_RS08250	COG4471	UPF0298 protein
KP952_RS08255	COG0742	ribosomal rna small subunit methyltransferase
KP952_RS08260	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KP952_RS08265	COG3314	Sporulation integral membrane protein YlbJ
KP952_RS08270	COG1752	Esterase of the alpha-beta hydrolase superfamily
KP952_RS08275	COG3480	Lon protease (S16) C-terminal proteolytic domain
KP952_RS08280	COG1323	Belongs to the UPF0348 family
KP952_RS08290	COG1399	metal-binding, possibly nucleic acid-binding protein
KP952_RS08305	COG0454	-acetyltransferase
KP952_RS08310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KP952_RS08315	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KP952_RS08320	COG2001	Belongs to the MraZ family
KP952_RS08325	COG0275	rRNA processing
KP952_RS08330	COG4839	cell division protein FtsL
KP952_RS08335	COG0768	penicillin binding
KP952_RS08340	COG0768	penicillin binding
KP952_RS08345	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KP952_RS08350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KP952_RS08355	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KP952_RS08360	COG0772	Belongs to the SEDS family
KP952_RS08365	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KP952_RS08370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KP952_RS08375	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KP952_RS08380	COG3879	Bacterial protein of unknown function (DUF881)
KP952_RS08385	COG3879	Bacterial protein of unknown function (DUF881)
KP952_RS08390	COG3856	small basic protein
KP952_RS08395	COG0849	cell division
KP952_RS08400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KP952_RS08405	COG1404	Belongs to the peptidase S8 family
KP952_RS08405	COG4412	M6 family metalloprotease domain protein
KP952_RS08415	COG1191	sigma factor activity
KP952_RS08420	COG1191	sigma factor activity
KP952_RS08425	COG1119	ATPase activity
KP952_RS08430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KP952_RS08435	COG1873	PFAM PRC-barrel domain
KP952_RS08440	COG1496	oxidoreductase activity
KP952_RS08445	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KP952_RS08450	COG1799	cell septum assembly
KP952_RS08455	COG0762	integral membrane protein
KP952_RS08460	COG2302	S4 RNA-binding domain
KP952_RS08465	COG3599	regulation of cell shape
KP952_RS08470	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KP952_RS08475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KP952_RS08480	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KP952_RS08485	COG0564	pseudouridine synthase activity
KP952_RS08490	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KP952_RS08495	COG2233	PERMEase
KP952_RS08500	COG0540	Belongs to the ATCase OTCase family
KP952_RS08505	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KP952_RS08510	COG0505	Belongs to the CarA family
KP952_RS08515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KP952_RS08520	COG0543	2 iron, 2 sulfur cluster binding
KP952_RS08525	COG0167	dihydroorotate dehydrogenase activity
KP952_RS08530	COG0284	orotidine-5'-phosphate decarboxylase activity
KP952_RS08535	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KP952_RS08540	COG0175	sulfate reduction
KP952_RS08545	COG0306	phosphate transporter
KP952_RS08550	COG2046	Belongs to the sulfate adenylyltransferase family
KP952_RS08555	COG0529	Catalyzes the synthesis of activated sulfate
KP952_RS08560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KP952_RS08565	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KP952_RS08570	COG1648	precorrin-2 dehydrogenase activity
KP952_RS08580	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KP952_RS08585	COG1561	YicC-like family, N-terminal region
KP952_RS08595	COG0194	GDP metabolic process
KP952_RS08600	COG1758	RNA polymerase activity
KP952_RS08605	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KP952_RS08610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KP952_RS08615	COG0242	peptide deformylase activity
KP952_RS08620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KP952_RS08625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KP952_RS08625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KP952_RS08630	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KP952_RS08635	COG0631	protein serine/threonine phosphatase activity
KP952_RS08640	COG2815	serine threonine protein kinase
KP952_RS08640	COG0515	serine threonine protein kinase
KP952_RS08645	COG1162	GTPase activity
KP952_RS08650	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KP952_RS08655	COG1564	THIamine pyrophosphokinase
KP952_RS08665	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KP952_RS08670	COG1302	Protein conserved in bacteria
KP952_RS08675	COG1461	Dihydroxyacetone kinase
KP952_RS08680	COG1760	l-serine dehydratase
KP952_RS08685	COG1760	l-serine dehydratase
KP952_RS08690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KP952_RS08695	COG2050	protein possibly involved in aromatic compounds catabolism
KP952_RS08695	COG1349	DNA-binding transcription factor activity
KP952_RS08700	COG0416	fatty acid biosynthetic process
KP952_RS08705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KP952_RS08710	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS08720	COG0571	ribonuclease III activity
KP952_RS08725	COG1196	nuclear chromosome segregation
KP952_RS08730	COG0552	protein localization to endoplasmic reticulum
KP952_RS08740	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KP952_RS08745	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KP952_RS08750	COG0228	four-way junction DNA binding
KP952_RS08755	COG1837	Belongs to the UPF0109 family
KP952_RS08765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KP952_RS08770	COG0336	Belongs to the RNA methyltransferase TrmD family
KP952_RS08775	COG0335	large ribosomal subunit rRNA binding
KP952_RS08780	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KP952_RS08785	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KP952_RS08795	COG2257	FlhB HrpN YscU SpaS Family
KP952_RS08800	COG0045	succinate-CoA ligase (ADP-forming) activity
KP952_RS08805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KP952_RS08810	COG0758	DNA mediated transformation
KP952_RS08815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KP952_RS08820	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KP952_RS08825	COG4974	Belongs to the 'phage' integrase family
KP952_RS08830	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KP952_RS08835	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KP952_RS08840	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KP952_RS08845	COG1815	bacterial-type flagellum-dependent cell motility
KP952_RS08850	COG1558	bacterial-type flagellum-dependent cell motility
KP952_RS08855	COG1677	Flagellar hook-basal body complex protein FliE
KP952_RS08860	COG1766	The M ring may be actively involved in energy transduction
KP952_RS08865	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KP952_RS08870	COG1317	bacterial-type flagellum organization
KP952_RS08875	COG1157	protein secretion by the type III secretion system
KP952_RS08880	COG2882	bacterial-type flagellum organization
KP952_RS08885	COG3334	PFAM MgtE intracellular
KP952_RS08890	COG3144	bacterial-type flagellum assembly
KP952_RS08895	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KP952_RS08900	COG4786	Flagellar basal body rod
KP952_RS08905	COG1582	Flagellar protein (FlbD)
KP952_RS08910	COG1580	Controls the rotational direction of flagella during chemotaxis
KP952_RS08915	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KP952_RS08920	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KP952_RS08920	COG1776	CheC inhibitor of MCP methylation
KP952_RS08925	COG2201	protein-glutamate methylesterase activity
KP952_RS08930	COG3190	flagellar
KP952_RS08935	COG1338	Plays a role in the flagellum-specific transport system
KP952_RS08940	COG1987	bacterial-type flagellum assembly
KP952_RS08945	COG1684	flagellar biosynthetic protein fliR
KP952_RS08950	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KP952_RS08955	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KP952_RS08960	COG1419	protein localization to endoplasmic reticulum
KP952_RS08965	COG0455	bacterial-type flagellum organization
KP952_RS08970	COG2201	protein-glutamate methylesterase activity
KP952_RS08975	COG2198	Histidine kinase
KP952_RS08975	COG0643	Histidine kinase
KP952_RS08980	COG0835	chemotaxis
KP952_RS08990	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KP952_RS08995	COG1191	sigma factor activity
KP952_RS09005	COG0052	Belongs to the universal ribosomal protein uS2 family
KP952_RS09010	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KP952_RS09015	COG0528	UMP kinase activity
KP952_RS09020	COG0233	cytoplasmic translational termination
KP952_RS09025	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KP952_RS09030	COG4589	Belongs to the CDS family
KP952_RS09035	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KP952_RS09040	COG0750	zinc metalloprotease
KP952_RS09045	COG0442	prolyl-tRNA aminoacylation
KP952_RS09050	COG2176	DNA-directed DNA polymerase activity
KP952_RS09055	COG0779	Required for maturation of 30S ribosomal subunits
KP952_RS09060	COG0195	Participates in both transcription termination and antitermination
KP952_RS09065	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KP952_RS09070	COG1358	cellular component organization or biogenesis
KP952_RS09075	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KP952_RS09080	COG1550	Protein conserved in bacteria
KP952_RS09085	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KP952_RS09090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KP952_RS09095	COG0196	riboflavin kinase activity
KP952_RS09100	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KP952_RS09105	COG1185	polyribonucleotide nucleotidyltransferase activity
KP952_RS09110	COG0726	polysaccharide deacetylase
KP952_RS09115	COG0612	Peptidase, M16
KP952_RS09120	COG1873	PFAM PRC-barrel domain
KP952_RS09125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KP952_RS09130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KP952_RS09135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KP952_RS09140	COG0527	aspartate kinase activity
KP952_RS09145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KP952_RS09150	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KP952_RS09155	COG0740	serine-type endopeptidase activity
KP952_RS09165	COG1674	ftsk spoiiie
KP952_RS09165	COG4980	gas vesicle protein
KP952_RS09170	COG2188	Transcriptional regulator
KP952_RS09175	COG2814	Major facilitator Superfamily
KP952_RS09180	COG0612	Peptidase, M16
KP952_RS09185	COG0612	Peptidase, M16
KP952_RS09190	COG0300	oxidoreductase activity
KP952_RS09205	COG1426	Protein conserved in bacteria
KP952_RS09210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KP952_RS09215	COG1058	Belongs to the CinA family
KP952_RS09215	COG1546	Belongs to the CinA family
KP952_RS09220	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KP952_RS09225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KP952_RS09230	COG1418	mRNA catabolic process
KP952_RS09235	COG1692	metallophosphoesterase
KP952_RS09240	COG2359	stage V sporulation protein S
KP952_RS09245	COG1063	alcohol dehydrogenase
KP952_RS09250	COG0156	8-amino-7-oxononanoate synthase activity
KP952_RS09255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KP952_RS09260	COG4550	Control of competence regulator ComK, YlbF/YmcA
KP952_RS09270	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KP952_RS09275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KP952_RS09380	COG3226	Transcriptional regulator
KP952_RS09390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KP952_RS09395	COG1404	Belongs to the peptidase S8 family
KP952_RS09405	COG4195	phage-related replication protein
KP952_RS09410	COG1764	response to oxidative stress
KP952_RS09415	COG2076	Multidrug Resistance protein
KP952_RS09420	COG2076	Multidrug Resistance protein
KP952_RS09435	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KP952_RS09440	COG1923	regulation of RNA biosynthetic process
KP952_RS09455	COG1780	Probably involved in ribonucleotide reductase function
KP952_RS09460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KP952_RS09465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KP952_RS09470	COG4112	unkown
KP952_RS09475	COG0860	N-Acetylmuramoyl-L-alanine amidase
KP952_RS09480	COG0464	growth
KP952_RS09485	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KP952_RS09490	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KP952_RS09495	COG0789	Transcriptional regulator
KP952_RS09500	COG0174	glutamine synthetase
KP952_RS09505	COG4974	Belongs to the 'phage' integrase family
KP952_RS09525	COG3646	Phage regulatory protein
KP952_RS09525	COG3645	SOS response
KP952_RS09670	COG3953	SLT domain
KP952_RS09670	COG5412	phage tail tape measure protein
KP952_RS09715	COG1388	LysM domain
KP952_RS09715	COG5632	N-Acetylmuramoyl-L-alanine amidase
KP952_RS09715	COG3409	Peptidoglycan-binding domain 1 protein
KP952_RS09725	COG5444	nuclease activity
KP952_RS09760	COG4282	regulation of fungal-type cell wall biogenesis
KP952_RS09795	COG3655	Transcriptional regulator
KP952_RS09820	COG0135	phosphoribosylanthranilate isomerase activity
KP952_RS09825	COG2211	Major facilitator Superfamily
KP952_RS09840	COG3507	Belongs to the glycosyl hydrolase 43 family
KP952_RS09845	COG1940	carbohydrate kinase activity
KP952_RS09850	COG2115	Belongs to the xylose isomerase family
KP952_RS09855	COG1070	Carbohydrate kinase
KP952_RS09865	COG3328	transposase activity
KP952_RS09870	COG1525	nuclease
KP952_RS09875	COG2814	Major facilitator Superfamily
KP952_RS09880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KP952_RS09895	COG0756	dUTP diphosphatase activity
KP952_RS09935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KP952_RS09950	COG3832	glyoxalase III activity
KP952_RS09990	COG4195	phage-related replication protein
KP952_RS10000	COG0346	lactoylglutathione lyase activity
KP952_RS10005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KP952_RS10010	COG1388	LysM domain
KP952_RS10015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KP952_RS10020	COG4224	UPF0291 protein
KP952_RS10025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KP952_RS10035	COG3763	UPF0154 protein
KP952_RS10045	COG0785	Cytochrome C biogenesis protein
KP952_RS10050	COG2201	protein-glutamate methylesterase activity
KP952_RS10055	COG4846	Membrane protein involved in cytochrome C biogenesis
KP952_RS10065	COG0071	Belongs to the small heat shock protein (HSP20) family
KP952_RS10080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KP952_RS10085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KP952_RS10105	COG0824	Thioesterase
KP952_RS10115	COG4841	protein insertion into membrane
KP952_RS10120	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KP952_RS10125	COG1832	CoA-binding protein
KP952_RS10130	COG0187	DNA topoisomerase II activity
KP952_RS10135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KP952_RS10145	COG1115	amino acid carrier protein
KP952_RS10150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KP952_RS10160	COG5520	Belongs to the glycosyl hydrolase 30 family
KP952_RS10165	COG3507	Belongs to the glycosyl hydrolase 43 family
KP952_RS10170	COG2246	polysaccharide biosynthetic process
KP952_RS10175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KP952_RS10180	COG0586	Pfam SNARE associated Golgi protein
KP952_RS10185	COG2404	hydrolase activity, acting on ester bonds
KP952_RS10190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KP952_RS10195	COG1024	Enoyl-CoA hydratase
KP952_RS10200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KP952_RS10205	COG0511	ligase activity, forming carbon-carbon bonds
KP952_RS10210	COG0439	Biotin carboxylase
KP952_RS10215	COG0318	PFAM AMP-dependent synthetase and ligase
KP952_RS10220	COG1960	acyl-CoA dehydrogenase activity
KP952_RS10230	COG1649	PFAM Uncharacterised BCR, COG1649
KP952_RS10245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KP952_RS10250	COG2027	D-alanyl-D-alanine carboxypeptidase
KP952_RS10255	COG2017	converts alpha-aldose to the beta-anomer
KP952_RS10260	COG0534	Mate efflux family protein
KP952_RS10280	COG0582	viral genome integration into host DNA
KP952_RS10285	COG0166	Belongs to the GPI family
KP952_RS10290	COG0405	Gamma-glutamyltransferase
KP952_RS10295	COG0583	DNA-binding transcription factor activity
KP952_RS10300	COG0604	alcohol dehydrogenase
KP952_RS10305	COG0493	'glutamate synthase
KP952_RS10310	COG0067	glutamate synthase
KP952_RS10310	COG0069	glutamate synthase activity
KP952_RS10310	COG0070	glutamate synthase
KP952_RS10315	COG0583	DNA-binding transcription factor activity
KP952_RS10345	COG0300	oxidoreductase activity
KP952_RS10350	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KP952_RS10360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KP952_RS10375	COG1131	(ABC) transporter
KP952_RS10385	COG2814	Major facilitator Superfamily
KP952_RS10390	COG3328	transposase activity
KP952_RS10420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KP952_RS10440	COG5444	nuclease activity
KP952_RS10445	COG4282	regulation of fungal-type cell wall biogenesis
KP952_RS10450	COG1231	oxidoreductase activity
KP952_RS10455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KP952_RS10460	COG2207	Transcriptional regulator
KP952_RS10460	COG0662	Cupin 2, conserved barrel domain protein
KP952_RS10465	COG0456	acetyltransferase
KP952_RS10470	COG1309	transcriptional regulator
KP952_RS10475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KP952_RS10480	COG3708	Transcriptional regulator
KP952_RS10485	COG2378	regulation of single-species biofilm formation
KP952_RS10495	COG0640	Transcriptional regulator
KP952_RS10500	COG0741	lytic transglycosylase activity
KP952_RS10505	COG2322	membrane
KP952_RS10520	COG1619	proteins homologs of microcin C7 resistance protein MccF
KP952_RS10525	COG3239	Fatty acid desaturase
KP952_RS10530	COG4585	Histidine kinase
KP952_RS10535	COG2197	response regulator
KP952_RS10540	COG3584	3D domain protein
KP952_RS10540	COG1388	LysM domain
KP952_RS10545	COG0514	ATP-dependent DNA helicase (RecQ)
KP952_RS10555	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KP952_RS10560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KP952_RS10575	COG0071	Belongs to the small heat shock protein (HSP20) family
KP952_RS10600	COG1012	belongs to the aldehyde dehydrogenase family
KP952_RS10605	COG1657	PFAM Prenyltransferase squalene oxidase
KP952_RS10610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KP952_RS10615	COG0733	neurotransmitter:sodium symporter activity
KP952_RS10620	COG0385	Bile acid
KP952_RS10625	COG0508	dehydrogenase complex catalyzes the overall conversion of
KP952_RS10630	COG0567	Dehydrogenase, E1 component
KP952_RS10635	COG4548	von Willebrand factor, type A
KP952_RS10640	COG0714	Associated with various cellular activities
KP952_RS10645	COG2032	superoxide dismutase activity
KP952_RS10650	COG0791	NLP P60 protein
KP952_RS10650	COG1388	LysM domain
KP952_RS10655	COG1819	glycosyl
KP952_RS10660	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KP952_RS10665	COG0534	Mate efflux family protein
KP952_RS10670	COG1366	Belongs to the anti-sigma-factor antagonist family
KP952_RS10675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KP952_RS10680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KP952_RS10690	COG2962	Rard protein
KP952_RS10705	COG2610	gluconate transmembrane transporter activity
KP952_RS10710	COG1942	4-Oxalocrotonate Tautomerase
KP952_RS10715	COG1733	regulation of RNA biosynthetic process
KP952_RS10720	COG0778	Nitroreductase
KP952_RS10730	COG0400	carboxylic ester hydrolase activity
KP952_RS10735	COG0346	lactoylglutathione lyase activity
KP952_RS10745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KP952_RS10750	COG3409	Peptidoglycan-binding domain 1 protein
KP952_RS10750	COG0793	Belongs to the peptidase S41A family
KP952_RS10755	COG2226	methyltransferase
KP952_RS10765	COG1876	peptidase activity
KP952_RS10770	COG0813	purine-nucleoside phosphorylase activity
KP952_RS10785	COG0671	phosphoesterase, PA-phosphatase related
KP952_RS10805	COG4479	Belongs to the UPF0346 family
KP952_RS10815	COG1509	lysine 2,3-aminomutase activity
KP952_RS10820	COG0456	acetyltransferase
KP952_RS10825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KP952_RS10835	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KP952_RS10840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KP952_RS10855	COG0456	acetyltransferase
KP952_RS10860	COG0463	Glycosyl transferase, family 2
KP952_RS10875	COG4641	Protein conserved in bacteria
KP952_RS10880	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
KP952_RS10885	COG1086	Polysaccharide biosynthesis protein
KP952_RS10890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KP952_RS10895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KP952_RS10900	COG1846	Transcriptional regulator
KP952_RS10905	COG0534	Mate efflux family protein
KP952_RS10915	COG4698	Protein conserved in bacteria
KP952_RS10920	COG2755	lipolytic protein G-D-S-L family
KP952_RS10925	COG1999	signal sequence binding
KP952_RS10935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KP952_RS10940	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KP952_RS10945	COG1272	protein, Hemolysin III
KP952_RS10950	COG0204	Acyl-transferase
KP952_RS10955	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KP952_RS10960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KP952_RS10970	COG2136	Putative SAM-dependent methyltransferase
KP952_RS10970	COG2521	methyltransferase
KP952_RS10980	COG0129	dihydroxy-acid dehydratase activity
KP952_RS10985	COG1413	lyase activity
KP952_RS10990	COG1418	mRNA catabolic process
KP952_RS10995	COG0386	Belongs to the glutathione peroxidase family
KP952_RS11000	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KP952_RS11005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KP952_RS11015	COG1278	Cold shock
KP952_RS11035	COG0328	RNA-DNA hybrid ribonuclease activity
KP952_RS11040	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KP952_RS11045	COG0328	RNA-DNA hybrid ribonuclease activity
KP952_RS11055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KP952_RS11070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KP952_RS11080	COG1755	Isoprenylcysteine carboxyl methyltransferase
KP952_RS11090	COG2233	PERMEase
KP952_RS11095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KP952_RS11100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KP952_RS11110	COG0800	Aldolase
KP952_RS11115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KP952_RS11120	COG1609	Transcriptional regulator
KP952_RS11125	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KP952_RS11130	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS11135	COG1199	ATP-dependent helicase activity
KP952_RS11150	COG0116	Belongs to the methyltransferase superfamily
KP952_RS11165	COG4474	Belongs to the UPF0398 family
KP952_RS11180	COG3359	exonuclease
KP952_RS11185	COG1205	dead DEAH box helicase
KP952_RS11185	COG1111	helicase
KP952_RS11190	COG2190	(PTS) system
KP952_RS11195	COG0071	Belongs to the small heat shock protein (HSP20) family
KP952_RS11230	COG3331	DNA recombination
KP952_RS11235	COG4499	WXG100 protein secretion system (Wss), protein YukC
KP952_RS11235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KP952_RS11245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KP952_RS11250	COG3935	DnaD domain protein
KP952_RS11255	COG0017	Asparaginyl-tRNA synthetase
KP952_RS11260	COG0436	Aminotransferase
KP952_RS11265	COG5353	protein conserved in bacteria
KP952_RS11275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KP952_RS11275	COG1199	ATP-dependent helicase activity
KP952_RS11280	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KP952_RS11285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KP952_RS11290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KP952_RS11295	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KP952_RS11295	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KP952_RS11300	COG0617	tRNA 3'-terminal CCA addition
KP952_RS11305	COG0438	transferase activity, transferring glycosyl groups
KP952_RS11310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KP952_RS11315	COG1803	Methylglyoxal synthase
KP952_RS11320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KP952_RS11325	COG1694	Mazg nucleotide pyrophosphohydrolase
KP952_RS11330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KP952_RS11340	COG4347	Protein of unknown function (DUF1405)
KP952_RS11345	COG2010	Cytochrome c
KP952_RS11345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KP952_RS11350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KP952_RS11355	COG0723	plastoquinol--plastocyanin reductase activity
KP952_RS11365	COG5582	Belongs to the UPF0302 family
KP952_RS11370	COG0457	Tetratricopeptide repeat
KP952_RS11375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KP952_RS11380	COG0287	Prephenate dehydrogenase
KP952_RS11395	COG0133	tryptophan synthase activity
KP952_RS11400	COG0135	phosphoribosylanthranilate isomerase activity
KP952_RS11410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KP952_RS11415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KP952_RS11420	COG4401	Chorismate mutase type I
KP952_RS11425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KP952_RS11430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KP952_RS11435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KP952_RS11440	COG0105	UTP biosynthetic process
KP952_RS11445	COG0142	geranyltranstransferase activity
KP952_RS11450	COG2226	methyltransferase
KP952_RS11455	COG0142	geranyltranstransferase activity
KP952_RS11465	COG0302	gtp cyclohydrolase
KP952_RS11470	COG0776	regulation of translation
KP952_RS11475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KP952_RS11490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KP952_RS11495	COG1160	GTP binding
KP952_RS11520	COG1304	FMN binding
KP952_RS11525	COG0539	negative regulation of cytoplasmic translation
KP952_RS11530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KP952_RS11540	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KP952_RS11545	COG2959	enzyme of heme biosynthesis
KP952_RS11550	COG3409	Peptidoglycan-binding domain 1 protein
KP952_RS11550	COG3773	Cell wall hydrolase
KP952_RS11555	COG2339	peptidase activity
KP952_RS11560	COG0492	ferredoxin-NADP+ reductase activity
KP952_RS11565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KP952_RS11570	COG4862	establishment of competence for transformation
KP952_RS11575	COG1408	metallophosphoesterase
KP952_RS11585	COG1388	LysM domain
KP952_RS11590	COG1266	CAAX protease self-immunity
KP952_RS11595	COG0514	ATP-dependent DNA helicase (RecQ)
KP952_RS11600	COG4955	Helix-turn-helix domain
KP952_RS11605	COG1141	Ferredoxin
KP952_RS11610	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KP952_RS11615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KP952_RS11620	COG0710	3-dehydroquinate dehydratase activity
KP952_RS11630	COG1595	DNA-templated transcription, initiation
KP952_RS11635	COG5002	protein histidine kinase activity
KP952_RS11640	COG0745	RESPONSE REGULATOR receiver
KP952_RS11645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KP952_RS11650	COG1333	cytochrome c biogenesis protein
KP952_RS11655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KP952_RS11660	COG1187	pseudouridine synthase activity
KP952_RS11665	COG0700	Nucleoside recognition
KP952_RS11670	COG2715	membrane protein required for spore maturation
KP952_RS11675	COG1686	Belongs to the peptidase S11 family
KP952_RS11685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KP952_RS11690	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KP952_RS11695	COG1547	Domain of unknown function (DUF309)
KP952_RS11700	COG0456	acetyltransferase
KP952_RS11705	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KP952_RS11710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KP952_RS11710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KP952_RS11715	COG0307	riboflavin synthase, alpha
KP952_RS11720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KP952_RS11720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KP952_RS11730	COG0681	Belongs to the peptidase S26 family
KP952_RS11740	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
KP952_RS11790	COG3328	transposase activity
KP952_RS11840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KP952_RS11850	COG4086	secreted protein
KP952_RS11855	COG0019	diaminopimelate decarboxylase activity
KP952_RS11860	COG0697	spore germination
KP952_RS11875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KP952_RS11895	COG1191	sigma factor activity
KP952_RS11900	COG2172	sigma factor antagonist activity
KP952_RS11905	COG1366	Belongs to the anti-sigma-factor antagonist family
KP952_RS11910	COG1686	Belongs to the peptidase S11 family
KP952_RS11915	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KP952_RS11920	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KP952_RS11925	COG4974	Belongs to the 'phage' integrase family
KP952_RS11935	COG0735	belongs to the Fur family
KP952_RS11940	COG1300	Membrane
KP952_RS11950	COG0281	malic enzyme
KP952_RS11955	COG1757	Na H antiporter
KP952_RS11960	COG1027	Aspartate ammonia-lyase
KP952_RS11965	COG0252	asparaginase activity
KP952_RS11970	COG1396	sequence-specific DNA binding
KP952_RS11975	COG1379	DNA repair
KP952_RS11980	COG0494	nUDIX hydrolase
KP952_RS11990	COG0667	Aldo Keto reductase
KP952_RS12000	COG1073	alpha beta
KP952_RS12010	COG4918	Iron-sulphur cluster biosynthesis
KP952_RS12015	COG0456	acetyltransferase
KP952_RS12015	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KP952_RS12020	COG2329	Antibiotic biosynthesis monooxygenase
KP952_RS12025	COG0456	acetyltransferase
KP952_RS12035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KP952_RS12045	COG2211	Major facilitator Superfamily
KP952_RS12055	COG0346	lactoylglutathione lyase activity
KP952_RS12060	COG1072	(Pantothenic acid kinase))
KP952_RS12065	COG3048	D-serine ammonia-lyase activity
KP952_RS12070	COG0300	oxidoreductase activity
KP952_RS12075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KP952_RS12080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KP952_RS12085	COG4187	Peptidase family M20/M25/M40
KP952_RS12090	COG1902	pentaerythritol trinitrate reductase activity
KP952_RS12100	COG0596	Alpha beta hydrolase
KP952_RS12110	COG1234	tRNA 3'-trailer cleavage
KP952_RS12115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KP952_RS12120	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KP952_RS12125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KP952_RS12135	COG0706	membrane insertase activity
KP952_RS12140	COG3361	conserved protein (COG2071)
KP952_RS12145	COG2195	Cleaves the N-terminal amino acid of tripeptides
KP952_RS12155	COG0346	lactoylglutathione lyase activity
KP952_RS12165	COG1376	ErfK ybiS ycfS ynhG family protein
KP952_RS12170	COG4129	membrane
KP952_RS12175	COG1126	abc transporter atp-binding protein
KP952_RS12180	COG0765	amino acid transport
KP952_RS12185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KP952_RS12195	COG1597	lipid kinase activity
KP952_RS12205	COG0789	Transcriptional regulator
KP952_RS12205	COG4978	Transcriptional regulator
KP952_RS12210	COG0508	dehydrogenase complex catalyzes the overall conversion of
KP952_RS12215	COG0022	dehydrogenase e1 component
KP952_RS12220	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KP952_RS12225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KP952_RS12230	COG3426	butyrate kinase activity
KP952_RS12235	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KP952_RS12240	COG0280	phosphate acetyltransferase
KP952_RS12245	COG3829	transcription factor binding
KP952_RS12245	COG3290	protein histidine kinase activity
KP952_RS12255	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KP952_RS12260	COG2079	MmgE PrpD family protein
KP952_RS12265	COG0372	Belongs to the citrate synthase family
KP952_RS12270	COG1960	acyl-CoA dehydrogenase activity
KP952_RS12275	COG1250	3-hydroxyacyl-CoA dehydrogenase
KP952_RS12280	COG0183	Belongs to the thiolase family
KP952_RS12285	COG0584	glycerophosphoryl diester phosphodiesterase
KP952_RS12290	COG0860	N-Acetylmuramoyl-L-alanine amidase
KP952_RS12305	COG1902	pentaerythritol trinitrate reductase activity
KP952_RS12310	COG0745	RESPONSE REGULATOR receiver
KP952_RS12315	COG0750	zinc metalloprotease
KP952_RS12320	COG0497	DNA recombination
KP952_RS12325	COG1438	arginine binding
KP952_RS12330	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KP952_RS12335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KP952_RS12340	COG0142	geranyltranstransferase activity
KP952_RS12345	COG1722	exodeoxyribonuclease VII activity
KP952_RS12350	COG1570	exodeoxyribonuclease VII activity
KP952_RS12355	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KP952_RS12360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KP952_RS12365	COG1302	Protein conserved in bacteria
KP952_RS12370	COG0439	Biotin carboxylase
KP952_RS12375	COG0511	ligase activity, forming carbon-carbon bonds
KP952_RS12420	COG3854	ATPases associated with a variety of cellular activities
KP952_RS12430	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KP952_RS12435	COG0006	proline dipeptidase activity
KP952_RS12440	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KP952_RS12450	COG3872	metal-dependent enzyme
KP952_RS12460	COG1752	Esterase of the alpha-beta hydrolase superfamily
KP952_RS12465	COG1321	iron dependent repressor
KP952_RS12470	COG0095	Lipoate-protein ligase
KP952_RS12475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KP952_RS12480	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KP952_RS12485	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KP952_RS12490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KP952_RS12495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KP952_RS12510	COG1396	sequence-specific DNA binding
KP952_RS12520	COG0681	Belongs to the peptidase S26 family
KP952_RS12545	COG4940	Competence protein ComGF
KP952_RS12555	COG4970	Tfp pilus assembly protein FimT
KP952_RS12560	COG4537	Required for transformation and DNA binding
KP952_RS12565	COG1459	type II secretion system
KP952_RS12570	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KP952_RS12575	COG0517	IMP dehydrogenase activity
KP952_RS12580	COG0598	Magnesium transport protein CorA
KP952_RS12585	COG1253	flavin adenine dinucleotide binding
KP952_RS12590	COG1366	Belongs to the anti-sigma-factor antagonist family
KP952_RS12600	COG1393	Belongs to the ArsC family
KP952_RS12610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KP952_RS12620	COG0011	TIGRFAM Protein of
KP952_RS12630	COG2866	Carboxypeptidase
KP952_RS12635	COG1368	sulfuric ester hydrolase activity
KP952_RS12640	COG1940	carbohydrate kinase activity
KP952_RS12645	COG4483	Protein conserved in bacteria
KP952_RS12650	COG0705	Rhomboid family
KP952_RS12650	COG0457	Tetratricopeptide repeat
KP952_RS12660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KP952_RS12670	COG0438	transferase activity, transferring glycosyl groups
KP952_RS12685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KP952_RS12690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KP952_RS12695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KP952_RS12700	COG0581	inorganic phosphate transmembrane transporter activity
KP952_RS12705	COG0573	inorganic phosphate transmembrane transporter activity
KP952_RS12710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KP952_RS12715	COG0768	penicillin binding
KP952_RS12720	COG0477	Major facilitator Superfamily
KP952_RS12725	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KP952_RS12730	COG2839	Protein conserved in bacteria
KP952_RS12735	COG5521	maltodextrose utilization protein MalA
KP952_RS12740	COG1388	LysM domain
KP952_RS12745	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KP952_RS12750	COG4709	membrane
KP952_RS12755	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KP952_RS12760	COG0735	belongs to the Fur family
KP952_RS12765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KP952_RS12775	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KP952_RS12780	COG0513	Belongs to the DEAD box helicase family
KP952_RS12790	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KP952_RS12795	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KP952_RS12800	COG2384	SAM-dependent methyltransferase
KP952_RS12805	COG2010	Cytochrome c
KP952_RS12810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KP952_RS12815	COG0358	DNA primase activity
KP952_RS12820	COG1671	Belongs to the UPF0178 family
KP952_RS12825	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KP952_RS12830	COG0517	IMP dehydrogenase activity
KP952_RS12835	COG0751	glycine-tRNA ligase activity
KP952_RS12840	COG0752	glycyl-tRNA synthetase alpha subunit
KP952_RS12845	COG1381	Involved in DNA repair and RecF pathway recombination
KP952_RS12855	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KP952_RS12860	COG0295	cytidine deaminase activity
KP952_RS12865	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KP952_RS12870	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KP952_RS12875	COG1480	7TM receptor with intracellular HD hydrolase
KP952_RS12880	COG1702	phosphate starvation-inducible protein PhoH
KP952_RS12885	COG0561	phosphatase activity
KP952_RS12900	COG4864	UPF0365 protein
KP952_RS12905	COG1030	water channel activity
KP952_RS12910	COG1610	YqeY-like protein
KP952_RS12920	COG1283	sodium-dependent phosphate transmembrane transporter activity
KP952_RS12925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KP952_RS12930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KP952_RS12935	COG2264	protein methyltransferase activity
KP952_RS12940	COG0484	heat shock protein binding
KP952_RS12945	COG0443	Heat shock 70 kDa protein
KP952_RS12950	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KP952_RS12955	COG1420	regulation of RNA biosynthetic process
KP952_RS12960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KP952_RS12965	COG0481	GTPase activity
KP952_RS12975	COG0860	N-Acetylmuramoyl-L-alanine amidase
KP952_RS12980	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KP952_RS12985	COG0268	Binds directly to 16S ribosomal RNA
KP952_RS12990	COG1466	dna polymerase III delta subunit
KP952_RS13010	COG2131	deaminase
KP952_RS13015	COG1596	polysaccharide export
KP952_RS13015	COG1555	photosystem II stabilization
KP952_RS13020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KP952_RS13025	COG2226	methyltransferase
KP952_RS13030	COG0799	negative regulation of ribosome biogenesis
KP952_RS13035	COG1713	HD superfamily hydrolase involved in NAD metabolism
KP952_RS13040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KP952_RS13045	COG1534	Rna-binding protein
KP952_RS13050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KP952_RS13055	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KP952_RS13060	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KP952_RS13070	COG2755	lipolytic protein G-D-S-L family
KP952_RS13075	COG5632	N-Acetylmuramoyl-L-alanine amidase
KP952_RS13075	COG3409	Peptidoglycan-binding domain 1 protein
KP952_RS13080	COG0398	Pfam SNARE associated Golgi protein
KP952_RS13085	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KP952_RS13095	COG3209	COG3209 Rhs family protein
KP952_RS13115	COG0114	fumarate hydratase activity
KP952_RS13120	COG0583	DNA-binding transcription factor activity
KP952_RS13130	COG0457	Tetratricopeptide repeat
KP952_RS13255	COG4978	Transcriptional regulator
KP952_RS13255	COG0789	Transcriptional regulator
KP952_RS13260	COG2814	Major facilitator Superfamily
KP952_RS13265	COG0456	acetyltransferase
KP952_RS13270	COG1253	flavin adenine dinucleotide binding
KP952_RS13280	COG0697	spore germination
KP952_RS13285	COG0583	DNA-binding transcription factor activity
KP952_RS13290	COG2072	flavoprotein involved in K transport
KP952_RS13295	COG1230	cation diffusion facilitator family transporter
KP952_RS13305	COG1114	Component of the transport system for branched-chain amino acids
KP952_RS13310	COG1687	branched-chain amino acid
KP952_RS13320	COG1522	sequence-specific DNA binding
KP952_RS13325	COG2732	(Barnase) inhibitor
KP952_RS13330	COG2124	cytochrome p450
KP952_RS13345	COG1335	isochorismatase
KP952_RS13360	COG2318	DinB family
KP952_RS13370	COG2070	2-Nitropropane dioxygenase
KP952_RS13375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KP952_RS13395	COG3443	Belongs to the bacterial solute-binding protein 9 family
KP952_RS13400	COG1595	DNA-templated transcription, initiation
KP952_RS13405	COG0667	Aldo Keto reductase
KP952_RS13410	COG3409	Peptidoglycan-binding domain 1 protein
KP952_RS13415	COG5566	PFAM Mor transcription activator
KP952_RS13420	COG0596	Alpha beta hydrolase
KP952_RS13425	COG4991	sh3 domain protein
KP952_RS13430	COG4991	sh3 domain protein
KP952_RS13440	COG0346	lactoylglutathione lyase activity
KP952_RS13450	COG5577	PFAM Coat F domain
KP952_RS13455	COG1063	alcohol dehydrogenase
KP952_RS13465	COG5577	PFAM Coat F domain
KP952_RS13470	COG0789	Transcriptional regulator
KP952_RS13480	COG1064	alcohol dehydrogenase
KP952_RS13485	COG0693	protein deglycase activity
KP952_RS13490	COG1621	beta-fructofuranosidase activity
KP952_RS13495	COG3716	PTS system mannose fructose sorbose family IID component
KP952_RS13500	COG3715	PTS system
KP952_RS13505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KP952_RS13510	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KP952_RS13515	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KP952_RS13515	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KP952_RS13525	COG1113	amino acid transport
KP952_RS13530	COG1280	lysine exporter protein (LysE YggA)
KP952_RS13535	COG1378	Sugar-specific transcriptional regulator TrmB
KP952_RS13540	COG1595	DNA-templated transcription, initiation
KP952_RS13560	COG2124	cytochrome p450
KP952_RS13560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KP952_RS13565	COG1309	transcriptional regulator
KP952_RS13570	COG2226	methyltransferase
KP952_RS13585	COG2116	formate transmembrane transporter activity
KP952_RS13590	COG5609	conserved protein (DUF2294)
KP952_RS13595	COG3383	formate dehydrogenase (NAD+) activity
KP952_RS13600	COG2427	Protein of unknown function (DUF1641)
KP952_RS13615	COG0626	cystathionine gamma-synthase activity
KP952_RS13620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KP952_RS13625	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KP952_RS13630	COG2226	methyltransferase
KP952_RS13645	COG0768	penicillin binding
KP952_RS13650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KP952_RS13655	COG0572	uridine kinase
KP952_RS13660	COG0826	peptidase U32
KP952_RS13665	COG0826	peptidase U32
KP952_RS13670	COG4122	O-methyltransferase activity
KP952_RS13675	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KP952_RS13680	COG3906	Belongs to the UPF0473 family
KP952_RS13685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KP952_RS13690	COG4472	Bacterial protein of unknown function (DUF965)
KP952_RS13695	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KP952_RS13700	COG0628	permease
KP952_RS13705	COG1126	abc transporter atp-binding protein
KP952_RS13710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KP952_RS13715	COG0765	amino acid transport
KP952_RS13720	COG0765	amino acid transport
KP952_RS13735	COG3881	PFAM PRC-barrel domain
KP952_RS13740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KP952_RS13745	COG0457	Tetratricopeptide repeat
KP952_RS13750	COG0482	sulfurtransferase activity
KP952_RS13755	COG1104	cysteine desulfurase activity
KP952_RS13760	COG1959	2 iron, 2 sulfur cluster binding
KP952_RS13765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KP952_RS13770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KP952_RS13780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KP952_RS13785	COG0124	histidyl-tRNA synthetase
KP952_RS13795	COG0860	N-Acetylmuramoyl-L-alanine amidase
KP952_RS13795	COG4991	sh3 domain protein
KP952_RS13795	COG3103	Sh3 type 3 domain protein
KP952_RS13800	COG1490	D-aminoacyl-tRNA deacylase activity
KP952_RS13805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KP952_RS13810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KP952_RS13815	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KP952_RS13815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KP952_RS13820	COG5416	Lipopolysaccharide assembly protein A domain
KP952_RS13825	COG0490	domain, Protein
KP952_RS13830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KP952_RS13830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KP952_RS13840	COG2244	polysaccharide biosynthetic process
KP952_RS13845	COG2323	membrane
KP952_RS13855	COG1862	Preprotein translocase
KP952_RS13860	COG0343	queuine tRNA-ribosyltransferase activity
KP952_RS13865	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KP952_RS13875	COG2255	four-way junction helicase activity
KP952_RS13880	COG0632	four-way junction helicase activity
KP952_RS13890	COG2814	Major facilitator Superfamily
KP952_RS13895	COG0673	inositol 2-dehydrogenase activity
KP952_RS13900	COG2112	serine threonine protein kinase
KP952_RS13920	COG1115	amino acid carrier protein
KP952_RS13925	COG0217	transcriptional regulatory protein
KP952_RS13935	COG1388	LysM domain
KP952_RS13940	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KP952_RS13945	COG0157	Belongs to the NadC ModD family
KP952_RS13950	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KP952_RS13955	COG1104	cysteine desulfurase activity
KP952_RS13960	COG1827	regulation of RNA biosynthetic process
KP952_RS13965	COG0077	Prephenate dehydratase
KP952_RS13970	COG4492	Belongs to the UPF0735 family
KP952_RS13975	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KP952_RS13980	COG3290	protein histidine kinase activity
KP952_RS13990	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KP952_RS13995	COG2868	ribosomal protein
KP952_RS14000	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KP952_RS14005	COG1994	Peptidase M50
KP952_RS14010	COG0739	heme binding
KP952_RS14015	COG2894	cell division
KP952_RS14020	COG0850	regulation of cytokinetic process
KP952_RS14025	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KP952_RS14035	COG1077	Cell shape determining protein MreB Mrl
KP952_RS14040	COG2003	Belongs to the UPF0758 family
KP952_RS14045	COG0424	maF-like protein
KP952_RS14055	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KP952_RS14060	COG0285	dihydrofolate synthase activity
KP952_RS14065	COG0525	valine-tRNA ligase activity
KP952_RS14075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KP952_RS14080	COG1388	LysM domain
KP952_RS14085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KP952_RS14090	COG0113	porphobilinogen synthase activity
KP952_RS14095	COG1587	Uroporphyrinogen-III synthase
KP952_RS14100	COG0181	hydroxymethylbilane synthase activity
KP952_RS14105	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KP952_RS14110	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KP952_RS14120	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KP952_RS14125	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KP952_RS14130	COG0470	DNA polymerase III
KP952_RS14130	COG1067	ATP-dependent peptidase activity
KP952_RS14135	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KP952_RS14140	COG0544	peptidyl-prolyl cis-trans isomerase activity
KP952_RS14145	COG1477	protein flavinylation
KP952_RS14145	COG0457	Tetratricopeptide repeat
KP952_RS14150	COG0066	3-isopropylmalate dehydratase activity
KP952_RS14155	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KP952_RS14160	COG0473	3-isopropylmalate dehydrogenase activity
KP952_RS14165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KP952_RS14170	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KP952_RS14175	COG0440	acetolactate synthase activity
KP952_RS14180	COG0028	Belongs to the TPP enzyme family
KP952_RS14195	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
KP952_RS14220	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KP952_RS14250	COG0622	Phosphoesterase
KP952_RS14255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KP952_RS14260	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KP952_RS14265	COG5401	PFAM Sporulation and spore germination
KP952_RS14270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KP952_RS14275	COG1846	Transcriptional regulator
KP952_RS14280	COG2197	response regulator
KP952_RS14285	COG0824	Thioesterase
KP952_RS14290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KP952_RS14295	COG1053	succinate dehydrogenase
KP952_RS14300	COG2009	succinate dehydrogenase
KP952_RS14305	COG1719	4-vinyl reductase, 4VR
KP952_RS14310	COG0527	aspartate kinase activity
KP952_RS14315	COG0322	excinuclease ABC activity
KP952_RS14320	COG3118	belongs to the thioredoxin family
KP952_RS14325	COG3534	alpha-L-arabinofuranosidase
KP952_RS14330	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KP952_RS14335	COG2086	electron transfer activity
KP952_RS14340	COG1024	Enoyl-CoA hydratase
KP952_RS14345	COG1309	transcriptional regulator
KP952_RS14350	COG0318	PFAM AMP-dependent synthetase and ligase
KP952_RS14355	COG3766	membrane
KP952_RS14360	COG1193	negative regulation of DNA recombination
KP952_RS14365	COG1796	DNA polymerase
KP952_RS14365	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KP952_RS14370	COG1286	toxin biosynthetic process
KP952_RS14375	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KP952_RS14380	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KP952_RS14385	COG0072	phenylalanine-tRNA ligase activity
KP952_RS14385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KP952_RS14390	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KP952_RS14400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KP952_RS14410	COG3835	regulator
KP952_RS14415	COG0277	FAD linked oxidase domain protein
KP952_RS14420	COG0247	lactate metabolic process
KP952_RS14425	COG0346	lactoylglutathione lyase activity
KP952_RS14430	COG1966	Carbon starvation protein
KP952_RS14435	COG3534	alpha-L-arabinofuranosidase
KP952_RS14440	COG0395	ABC-type sugar transport system, permease component
KP952_RS14445	COG1175	transmembrane transport
KP952_RS14450	COG1653	transport
KP952_RS14455	COG0371	Dehydrogenase
KP952_RS14460	COG0647	UMP catabolic process
KP952_RS14465	COG0235	Class ii aldolase
KP952_RS14470	COG1069	ribulokinase activity
KP952_RS14475	COG2160	L-arabinose isomerase activity
KP952_RS14480	COG3507	Belongs to the glycosyl hydrolase 43 family
KP952_RS14485	COG1363	Peptidase, m42
KP952_RS14495	COG3326	Membrane
KP952_RS14500	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KP952_RS14505	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KP952_RS14510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KP952_RS14520	COG1346	cytolysis
KP952_RS14525	COG1380	Effector of murein hydrolase LrgA
KP952_RS14530	COG3279	Response regulator of the LytR AlgR family
KP952_RS14535	COG3275	phosphorelay sensor kinase activity
KP952_RS14540	COG1011	Hydrolase
KP952_RS14545	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KP952_RS14555	COG0398	Pfam SNARE associated Golgi protein
KP952_RS14560	COG1484	DNA-dependent DNA replication
KP952_RS14565	COG3611	Membrane attachment protein
KP952_RS14570	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KP952_RS14575	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KP952_RS14580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KP952_RS14585	COG1733	regulation of RNA biosynthetic process
KP952_RS14590	COG2814	Major facilitator Superfamily
KP952_RS14595	COG0656	L-ascorbic acid biosynthetic process
KP952_RS14600	COG0237	dephospho-CoA kinase activity
KP952_RS14605	COG1971	Probably functions as a manganese efflux pump
KP952_RS14610	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KP952_RS14615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KP952_RS14615	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KP952_RS14620	COG5002	protein histidine kinase activity
KP952_RS14625	COG0745	RESPONSE REGULATOR receiver
KP952_RS14630	COG0039	L-malate dehydrogenase activity
KP952_RS14635	COG0538	isocitrate dehydrogenase activity
KP952_RS14640	COG0372	Belongs to the citrate synthase family
KP952_RS14645	COG2707	UPF0756 membrane protein
KP952_RS14650	COG0628	permease
KP952_RS14655	COG3030	protein affecting phage T7 exclusion by the F plasmid
KP952_RS14660	COG0469	pyruvate kinase activity
KP952_RS14665	COG0205	6-phosphofructokinase activity
KP952_RS14670	COG0825	malonyl-CoA metabolic process
KP952_RS14675	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KP952_RS14680	COG0281	malic enzyme
KP952_RS14685	COG0587	DNA-directed DNA polymerase activity
KP952_RS14705	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KP952_RS14715	COG4109	DRTGG domain
KP952_RS14725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KP952_RS14730	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS14735	COG0165	Argininosuccinate lyase
KP952_RS14740	COG0137	argininosuccinate synthase activity
KP952_RS14745	COG0521	Mo-molybdopterin cofactor biosynthetic process
KP952_RS14750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KP952_RS14760	COG0827	DNA restriction-modification system
KP952_RS14765	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KP952_RS14770	COG3874	Sporulation protein YtfJ
KP952_RS14780	COG1714	RDD family
KP952_RS14785	COG0616	signal peptide processing
KP952_RS14790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KP952_RS14795	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KP952_RS14800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KP952_RS14810	COG0301	tRNA thio-modification
KP952_RS14815	COG1104	cysteine desulfurase activity
KP952_RS14820	COG1114	Component of the transport system for branched-chain amino acids
KP952_RS14825	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KP952_RS14830	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KP952_RS14835	COG1309	transcriptional regulator
KP952_RS14840	COG1956	GAF domain-containing protein
KP952_RS14845	COG2203	Gaf domain
KP952_RS14845	COG2199	diguanylate cyclase activity
KP952_RS14850	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KP952_RS14855	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KP952_RS14860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KP952_RS14865	COG0454	-acetyltransferase
KP952_RS14870	COG0517	IMP dehydrogenase activity
KP952_RS14875	COG0123	including yeast histone deacetylase and acetoin utilization protein
KP952_RS14880	COG1360	Flagellar Motor Protein
KP952_RS14885	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KP952_RS14890	COG1609	Transcriptional regulator
KP952_RS14895	COG1605	Chorismate mutase
KP952_RS14895	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KP952_RS14900	COG3118	belongs to the thioredoxin family
KP952_RS14905	COG4980	gas vesicle protein
KP952_RS14910	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KP952_RS14915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KP952_RS14920	COG1674	ftsk spoiiie
KP952_RS14925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KP952_RS14930	COG4848	Belongs to the UPF0354 family
KP952_RS14935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KP952_RS14950	COG1363	Peptidase, m42
KP952_RS14955	COG5584	Small secreted protein
KP952_RS14960	COG0281	malic enzyme
KP952_RS14965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KP952_RS14970	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KP952_RS14980	COG0510	thiamine kinase activity
KP952_RS14985	COG1523	belongs to the glycosyl hydrolase 13 family
KP952_RS14990	COG1597	lipid kinase activity
KP952_RS15000	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KP952_RS15005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KP952_RS15010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KP952_RS15015	COG2252	PERMEase
KP952_RS15020	COG4473	ABC transporter
KP952_RS15025	COG1131	(ABC) transporter
KP952_RS15030	COG1349	DNA-binding transcription factor activity
KP952_RS15035	COG1187	pseudouridine synthase activity
KP952_RS15040	COG2244	polysaccharide biosynthetic process
KP952_RS15045	COG2081	HI0933 family
KP952_RS15050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KP952_RS15070	COG1653	transport
KP952_RS15075	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KP952_RS15080	COG4209	transmembrane transport
KP952_RS15090	COG1653	transport
KP952_RS15095	COG0395	ABC-type sugar transport system, permease component
KP952_RS15100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KP952_RS15105	COG2124	cytochrome p450
KP952_RS15110	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KP952_RS15125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KP952_RS15135	COG1073	alpha beta
KP952_RS15140	COG1609	Transcriptional regulator
KP952_RS15145	COG1653	transport
KP952_RS15150	COG1175	transmembrane transport
KP952_RS15155	COG0395	ABC-type sugar transport system, permease component
KP952_RS15160	COG1486	melibiose metabolic process
KP952_RS15165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KP952_RS15170	COG0495	leucyl-tRNA aminoacylation
KP952_RS15180	COG2202	Pas domain
KP952_RS15180	COG1366	Belongs to the anti-sigma-factor antagonist family
KP952_RS15185	COG2814	Major facilitator Superfamily
KP952_RS15195	COG0577	efflux transmembrane transporter activity
KP952_RS15200	COG1136	(ABC) transporter
KP952_RS15205	COG2205	protein histidine kinase activity
KP952_RS15210	COG0745	RESPONSE REGULATOR receiver
KP952_RS15215	COG0577	efflux transmembrane transporter activity
KP952_RS15220	COG1136	(ABC) transporter
KP952_RS15235	COG1131	(ABC) transporter
KP952_RS15240	COG1725	Transcriptional regulator
KP952_RS15255	COG1242	4 iron, 4 sulfur cluster binding
KP952_RS15260	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KP952_RS15270	COG2267	carboxylic ester hydrolase activity
KP952_RS15275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KP952_RS15280	COG1113	amino acid transport
KP952_RS15285	COG0367	asparagine synthase
KP952_RS15290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KP952_RS15295	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KP952_RS15305	COG1506	peptidase
KP952_RS15310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KP952_RS15315	COG1116	anion transmembrane transporter activity
KP952_RS15320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KP952_RS15325	COG0494	nUDIX hydrolase
KP952_RS15330	COG4824	toxin secretion phage lysis holin
KP952_RS15335	COG0783	Belongs to the Dps family
KP952_RS15350	COG1854	S-ribosylhomocysteine lyase activity
KP952_RS15355	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KP952_RS15360	COG0288	reversible hydration of carbon dioxide
KP952_RS15365	COG0254	rRNA binding
KP952_RS15370	COG1271	oxidase subunit
KP952_RS15375	COG1294	oxidase, subunit
KP952_RS15385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KP952_RS15390	COG1321	iron dependent repressor
KP952_RS15390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KP952_RS15395	COG1121	(ABC) transporter
KP952_RS15400	COG0803	Belongs to the bacterial solute-binding protein 9 family
KP952_RS15405	COG4948	Mandelate Racemase Muconate Lactonizing
KP952_RS15410	COG0318	PFAM AMP-dependent synthetase and ligase
KP952_RS15415	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KP952_RS15420	COG0596	Alpha beta hydrolase
KP952_RS15425	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KP952_RS15430	COG1169	isochorismate synthase
KP952_RS15435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KP952_RS15440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KP952_RS15445	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KP952_RS15450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KP952_RS15455	COG0438	transferase activity, transferring glycosyl groups
KP952_RS15465	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KP952_RS15470	COG0438	transferase activity, transferring glycosyl groups
KP952_RS15475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KP952_RS15480	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KP952_RS15485	COG0058	SHG alpha-glucan phosphorylase activity
KP952_RS15490	COG0297	glycogen (starch) synthase activity
KP952_RS15495	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KP952_RS15500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KP952_RS15505	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KP952_RS15630	COG3859	Proton-coupled thiamine transporter YuaJ
KP952_RS15635	COG1247	-acetyltransferase
KP952_RS15640	COG2268	Band 7 protein
KP952_RS15645	COG1585	Membrane protein implicated in regulation of membrane protease activity
KP952_RS15650	COG2318	DinB family
KP952_RS15660	COG1454	alcohol dehydrogenase
KP952_RS15665	COG1012	belongs to the aldehyde dehydrogenase family
KP952_RS15670	COG1510	regulation of RNA biosynthetic process
KP952_RS15680	COG0569	domain protein
KP952_RS15685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KP952_RS15690	COG4682	membrane
KP952_RS15695	COG1705	Flagellar rod assembly protein muramidase FlgJ
KP952_RS15700	COG0477	Major facilitator Superfamily
KP952_RS15705	COG5553	Cysteine dioxygenase type I
KP952_RS15715	COG1968	undecaprenyl-diphosphatase activity
KP952_RS15720	COG0628	permease
KP952_RS15725	COG0673	inositol 2-dehydrogenase activity
KP952_RS15730	COG4806	L-rhamnose isomerase
KP952_RS15735	COG3254	rhamnose metabolic process
KP952_RS15740	COG1070	Carbohydrate kinase
KP952_RS15745	COG1349	DNA-binding transcription factor activity
KP952_RS15750	COG3347	Dehydrogenase
KP952_RS15750	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS15760	COG0840	transmembrane signaling receptor activity
KP952_RS15765	COG0840	transmembrane signaling receptor activity
KP952_RS15770	COG0840	transmembrane signaling receptor activity
KP952_RS15785	COG0432	Pfam Uncharacterised protein family UPF0047
KP952_RS15795	COG0366	Alpha amylase catalytic
KP952_RS15800	COG1253	flavin adenine dinucleotide binding
KP952_RS15805	COG2738	Putative neutral zinc metallopeptidase
KP952_RS15820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KP952_RS15835	COG0166	Belongs to the GPI family
KP952_RS15840	COG1979	alcohol dehydrogenase
KP952_RS15845	COG1979	alcohol dehydrogenase
KP952_RS15850	COG2155	Conserved Protein
KP952_RS15855	COG1098	S1 RNA binding domain
KP952_RS15860	COG0436	Aminotransferase
KP952_RS15865	COG1522	sequence-specific DNA binding
KP952_RS15870	COG2267	carboxylic ester hydrolase activity
KP952_RS15880	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KP952_RS15885	COG2205	protein histidine kinase activity
KP952_RS15895	COG5018	Exonuclease
KP952_RS15900	COG2814	Major facilitator Superfamily
KP952_RS15905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KP952_RS15910	COG3011	Protein conserved in bacteria
KP952_RS15920	COG3290	protein histidine kinase activity
KP952_RS15925	COG4565	transcriptional regulatory protein
KP952_RS15930	COG1744	ABC transporter substrate-binding protein PnrA-like
KP952_RS15935	COG3845	ABC transporter
KP952_RS15940	COG4603	Belongs to the binding-protein-dependent transport system permease family
KP952_RS15945	COG1079	Belongs to the binding-protein-dependent transport system permease family
KP952_RS15950	COG3493	citrate carrier protein
KP952_RS15960	COG2111	Na H antiporter
KP952_RS15960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KP952_RS15965	COG2111	Na H antiporter
KP952_RS15970	COG1006	Multisubunit Na H antiporter MnhC subunit
KP952_RS15975	COG0651	ATP synthesis coupled electron transport
KP952_RS15980	COG1863	multisubunit Na H antiporter MnhE subunit
KP952_RS15985	COG2212	antiporter activity
KP952_RS15990	COG1320	monovalent cation:proton antiporter activity
KP952_RS15995	COG2050	protein possibly involved in aromatic compounds catabolism
KP952_RS16000	COG2197	response regulator
KP952_RS16005	COG4585	Histidine kinase
KP952_RS16015	COG0142	geranyltranstransferase activity
KP952_RS16035	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KP952_RS16040	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KP952_RS16045	COG1335	isochorismatase
KP952_RS16050	COG5506	Protein of unknown function (DUF1694)
KP952_RS16065	COG0628	permease
KP952_RS16080	COG1418	mRNA catabolic process
KP952_RS16085	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS16095	COG1511	domain protein
KP952_RS16100	COG1674	ftsk spoiiie
KP952_RS16100	COG0433	COG0433 Predicted ATPase
KP952_RS16105	COG4499	WXG100 protein secretion system (Wss), protein YukC
KP952_RS16110	COG5417	Belongs to the EsaB family
KP952_RS16115	COG4842	Belongs to the WXG100 family
KP952_RS16120	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KP952_RS16120	COG2508	Transcriptional regulator
KP952_RS16125	COG0686	Belongs to the AlaDH PNT family
KP952_RS16130	COG5634	Uncharacterized conserved protein (DUF2278)
KP952_RS16135	COG3251	PFAM MbtH domain protein
KP952_RS16140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KP952_RS16145	COG1535	isochorismatase
KP952_RS16145	COG3433	isochorismatase activity
KP952_RS16150	COG1021	2,3-dihydroxybenzoate-AMP ligase
KP952_RS16155	COG1169	isochorismate synthase
KP952_RS16160	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS16165	COG2819	hydrolase of the alpha beta superfamily
KP952_RS16170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KP952_RS16175	COG1268	BioY protein
KP952_RS16180	COG2056	Na+-H+ antiporter family
KP952_RS16185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KP952_RS16190	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KP952_RS16195	COG3584	3D domain protein
KP952_RS16210	COG1252	NADH dehydrogenase
KP952_RS16215	COG0492	ferredoxin-NADP+ reductase activity
KP952_RS16225	COG0516	GMP reductase activity
KP952_RS16230	COG2808	Putative FMN-binding domain
KP952_RS16235	COG0456	acetyltransferase
KP952_RS16345	COG0582	viral genome integration into host DNA
KP952_RS16355	COG4974	Belongs to the 'phage' integrase family
KP952_RS16360	COG0316	Belongs to the HesB IscA family
KP952_RS16365	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KP952_RS16370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KP952_RS16375	COG4844	belongs to the
KP952_RS16380	COG1252	NADH dehydrogenase
KP952_RS16385	COG4837	Protein of unknown function (DUF1462)
KP952_RS16390	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KP952_RS16395	COG4946	Tricorn protease homolog
KP952_RS16395	COG0823	Involved in the tonB-independent uptake of proteins
KP952_RS16395	COG1506	peptidase
KP952_RS16400	COG0083	homoserine kinase activity
KP952_RS16405	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KP952_RS16410	COG0460	homoserine dehydrogenase
KP952_RS16415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KP952_RS16420	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KP952_RS16425	COG0647	UMP catabolic process
KP952_RS16430	COG2445	Protein of unknown function DUF86
KP952_RS16435	COG4470	Protein conserved in bacteria
KP952_RS16445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KP952_RS16450	COG0739	heme binding
KP952_RS16460	COG3377	Domain of unknown function (DUF1805)
KP952_RS16465	COG0737	Belongs to the 5'-nucleotidase family
KP952_RS16470	COG0730	response to heat
KP952_RS16475	COG1801	Protein of unknown function DUF72
KP952_RS16485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KP952_RS16490	COG2508	Transcriptional regulator
KP952_RS16495	COG2233	PERMEase
KP952_RS16500	COG2233	PERMEase
KP952_RS16505	COG3195	allantoin biosynthetic process
KP952_RS16505	COG3648	Uricase
KP952_RS16510	COG2351	hydroxyisourate hydrolase activity
KP952_RS16520	COG2080	2 iron, 2 sulfur cluster binding
KP952_RS16525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KP952_RS16530	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KP952_RS16535	COG2068	MobA-Related Protein
KP952_RS16540	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KP952_RS16545	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KP952_RS16550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KP952_RS16560	COG2356	endonuclease I
KP952_RS16565	COG3842	ATPase activity
KP952_RS16570	COG2188	Transcriptional regulator
KP952_RS16575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KP952_RS16585	COG1175	transmembrane transport
KP952_RS16590	COG1653	transport
KP952_RS16595	COG2222	sugar isomerase
KP952_RS16600	COG0322	excinuclease ABC activity
KP952_RS16605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KP952_RS16620	COG0346	lactoylglutathione lyase activity
KP952_RS16625	COG0640	Transcriptional regulator
KP952_RS16630	COG0719	Fe-S assembly protein
KP952_RS16635	COG0822	iron-sulfur transferase activity
KP952_RS16640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KP952_RS16645	COG0719	Fe-S assembly protein
KP952_RS16650	COG0396	ATPase activity
KP952_RS16660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KP952_RS16665	COG1464	Belongs to the NlpA lipoprotein family
KP952_RS16670	COG2011	ABC-type metal ion transport system permease component
KP952_RS16675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KP952_RS16685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KP952_RS16690	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KP952_RS16700	COG0509	glycine decarboxylation via glycine cleavage system
KP952_RS16705	COG1393	Belongs to the ArsC family
KP952_RS16710	COG1960	acyl-CoA dehydrogenase activity
KP952_RS16715	COG0183	Belongs to the thiolase family
KP952_RS16720	COG1250	3-hydroxyacyl-CoA dehydrogenase
KP952_RS16720	COG1024	Enoyl-CoA hydratase
KP952_RS16730	COG0506	proline dehydrogenase activity
KP952_RS16740	COG5577	PFAM Coat F domain
KP952_RS16745	COG1846	Transcriptional regulator
KP952_RS16750	COG0477	Major facilitator Superfamily
KP952_RS16755	COG1942	4-Oxalocrotonate Tautomerase
KP952_RS16760	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS16765	COG0583	DNA-binding transcription factor activity
KP952_RS16775	COG1120	ATPase activity
KP952_RS16795	COG1131	(ABC) transporter
KP952_RS16840	COG0783	Belongs to the Dps family
KP952_RS16845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KP952_RS16850	COG0745	RESPONSE REGULATOR receiver
KP952_RS16855	COG2770	Histidine kinase
KP952_RS16855	COG2205	protein histidine kinase activity
KP952_RS16865	COG1309	transcriptional regulator
KP952_RS16870	COG0114	fumarate hydratase activity
KP952_RS16880	COG0697	spore germination
KP952_RS16885	COG0814	amino acid
KP952_RS16895	COG2197	response regulator
KP952_RS16900	COG4585	Histidine kinase
KP952_RS16905	COG4758	membrane
KP952_RS16910	COG3595	metallopeptidase activity
KP952_RS16915	COG1842	Phage shock protein A
KP952_RS16920	COG4758	membrane
KP952_RS16925	COG2814	Major facilitator Superfamily
KP952_RS16930	COG2096	Adenosyltransferase
KP952_RS16935	COG1120	ATPase activity
KP952_RS16940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KP952_RS16945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KP952_RS16950	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS16955	COG3386	PFAM SMP-30 Gluconolaconase
KP952_RS16960	COG2205	protein histidine kinase activity
KP952_RS16965	COG0745	RESPONSE REGULATOR receiver
KP952_RS16985	COG2140	Oxalate decarboxylase
KP952_RS16995	COG0577	efflux transmembrane transporter activity
KP952_RS17000	COG1136	(ABC) transporter
KP952_RS17005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KP952_RS17010	COG1120	ATPase activity
KP952_RS17015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KP952_RS17020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KP952_RS17025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KP952_RS17030	COG0531	amino acid
KP952_RS17040	COG1988	membrane-bound metal-dependent
KP952_RS17045	COG1368	sulfuric ester hydrolase activity
KP952_RS17050	COG1910	domain protein
KP952_RS17055	COG0725	ABC transporter, periplasmic molybdate-binding protein
KP952_RS17060	COG4149	molybdate abc transporter
KP952_RS17065	COG0656	L-ascorbic acid biosynthetic process
KP952_RS17075	COG0025	NhaP-type Na H and K H
KP952_RS17080	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KP952_RS17085	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KP952_RS17090	COG3973	AAA domain
KP952_RS17100	COG2860	membrane
KP952_RS17105	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KP952_RS17110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KP952_RS17115	COG2217	Heavy metal translocating P-type atpase
KP952_RS17120	COG2217	Heavy metal translocating P-type atpase
KP952_RS17125	COG2608	mercury ion transmembrane transporter activity
KP952_RS17130	COG1937	Protein conserved in bacteria
KP952_RS17135	COG0673	inositol 2-dehydrogenase activity
KP952_RS17145	COG1289	transmembrane transporter activity
KP952_RS17155	COG2076	Multidrug Resistance protein
KP952_RS17160	COG1309	transcriptional regulator
KP952_RS17165	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS17175	COG5444	nuclease activity
KP952_RS17190	COG5632	N-Acetylmuramoyl-L-alanine amidase
KP952_RS17190	COG3409	Peptidoglycan-binding domain 1 protein
KP952_RS17195	COG4824	toxin secretion phage lysis holin
KP952_RS17220	COG1705	Flagellar rod assembly protein muramidase FlgJ
KP952_RS17220	COG3942	CHAP domain
KP952_RS17460	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KP952_RS17465	COG0557	exoribonuclease II activity
KP952_RS17470	COG1647	Serine aminopeptidase, S33
KP952_RS17475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KP952_RS17480	COG0596	Alpha beta hydrolase
KP952_RS17485	COG1476	TRANSCRIPTIONal
KP952_RS17490	COG1396	sequence-specific DNA binding
KP952_RS17495	COG1396	sequence-specific DNA binding
KP952_RS17500	COG1733	regulation of RNA biosynthetic process
KP952_RS17505	COG0840	transmembrane signaling receptor activity
KP952_RS17510	COG1174	glycine betaine transport
KP952_RS17515	COG1732	Glycine betaine
KP952_RS17520	COG1174	glycine betaine transport
KP952_RS17525	COG0517	IMP dehydrogenase activity
KP952_RS17525	COG1125	glycine betaine transport
KP952_RS17530	COG1510	regulation of RNA biosynthetic process
KP952_RS17535	COG1174	glycine betaine transport
KP952_RS17540	COG1732	Glycine betaine
KP952_RS17545	COG1174	glycine betaine transport
KP952_RS17550	COG1125	glycine betaine transport
KP952_RS17550	COG0517	IMP dehydrogenase activity
KP952_RS17555	COG1510	regulation of RNA biosynthetic process
KP952_RS17560	COG2095	MarC family integral membrane protein
KP952_RS17575	COG4640	response to antibiotic
KP952_RS17580	COG0456	acetyltransferase
KP952_RS17585	COG0148	phosphopyruvate hydratase activity
KP952_RS17590	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KP952_RS17595	COG0149	triose-phosphate isomerase activity
KP952_RS17600	COG0126	phosphoglycerate kinase activity
KP952_RS17605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KP952_RS17610	COG2390	Transcriptional regulator
KP952_RS17615	COG2814	Major facilitator Superfamily
KP952_RS17620	COG1609	Transcriptional regulator
KP952_RS17625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KP952_RS17630	COG0583	DNA-binding transcription factor activity
KP952_RS17635	COG0697	spore germination
KP952_RS17640	COG1113	amino acid transport
KP952_RS17650	COG1556	Lactate utilization protein
KP952_RS17655	COG1139	Iron-sulfur cluster binding protein
KP952_RS17660	COG0247	lactate metabolic process
KP952_RS17665	COG2197	response regulator
KP952_RS17670	COG4585	Histidine kinase
KP952_RS17675	COG0842	Transport permease protein
KP952_RS17680	COG1131	(ABC) transporter
KP952_RS17700	COG0596	Alpha beta hydrolase
KP952_RS17705	COG2208	phosphoserine phosphatase activity
KP952_RS17710	COG3867	Arabinogalactan endo-beta-1,4-galactanase
KP952_RS17715	COG1874	Beta-galactosidase
KP952_RS17720	COG3833	ABC-type maltose transport systems, permease component
KP952_RS17725	COG1175	transmembrane transport
KP952_RS17730	COG2182	Extracellular solute-binding protein
KP952_RS17735	COG1609	Transcriptional regulator
KP952_RS17740	COG2186	Transcriptional regulator
KP952_RS17745	COG1620	l-lactate permease
KP952_RS17750	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KP952_RS17760	COG5039	Polysaccharide pyruvyl transferase
KP952_RS17765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KP952_RS17770	COG0110	maltose O-acetyltransferase activity
KP952_RS17775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KP952_RS17780	COG2244	polysaccharide biosynthetic process
KP952_RS17785	COG1216	Glycosyl transferase, family 2
KP952_RS17790	COG5039	Polysaccharide pyruvyl transferase
KP952_RS17795	COG1216	Glycosyl transferase, family 2
KP952_RS17805	COG0438	transferase activity, transferring glycosyl groups
KP952_RS17810	COG1215	transferase activity, transferring glycosyl groups
KP952_RS17815	COG0438	transferase activity, transferring glycosyl groups
KP952_RS17820	COG1086	Polysaccharide biosynthesis protein
KP952_RS17825	COG0489	protein tyrosine kinase activity
KP952_RS17830	COG3944	biosynthesis protein
KP952_RS17835	COG1396	sequence-specific DNA binding
KP952_RS17840	COG2272	Belongs to the type-B carboxylesterase lipase family
KP952_RS17850	COG3479	Phenolic acid decarboxylase
KP952_RS17865	COG1794	racemase activity, acting on amino acids and derivatives
KP952_RS17875	COG1621	beta-fructofuranosidase activity
KP952_RS17880	COG1621	beta-fructofuranosidase activity
KP952_RS17885	COG0531	amino acid
KP952_RS17890	COG1309	transcriptional regulator
KP952_RS17895	COG2076	Multidrug Resistance protein
KP952_RS17900	COG2076	Multidrug Resistance protein
KP952_RS17920	COG1674	ftsk spoiiie
KP952_RS17940	COG1388	LysM domain
KP952_RS17940	COG3409	Peptidoglycan-binding domain 1 protein
KP952_RS17940	COG5632	N-Acetylmuramoyl-L-alanine amidase
KP952_RS17975	COG1705	Flagellar rod assembly protein muramidase FlgJ
KP952_RS18055	COG0582	viral genome integration into host DNA
KP952_RS18165	COG4974	Belongs to the 'phage' integrase family
KP952_RS18175	COG0740	serine-type endopeptidase activity
KP952_RS18180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KP952_RS18185	COG0366	Alpha amylase catalytic
KP952_RS18190	COG1554	hydrolase, family 65, central catalytic
KP952_RS18195	COG5521	maltodextrose utilization protein MalA
KP952_RS18200	COG3833	ABC-type maltose transport systems, permease component
KP952_RS18205	COG1175	transmembrane transport
KP952_RS18210	COG2182	Extracellular solute-binding protein
KP952_RS18215	COG0366	Alpha amylase catalytic
KP952_RS18220	COG1609	Transcriptional regulator
KP952_RS18225	COG1611	Belongs to the LOG family
KP952_RS18235	COG0659	secondary active sulfate transmembrane transporter activity
KP952_RS18240	COG0288	reversible hydration of carbon dioxide
KP952_RS18245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KP952_RS18250	COG0577	efflux transmembrane transporter activity
KP952_RS18255	COG1136	(ABC) transporter
KP952_RS18260	COG5002	protein histidine kinase activity
KP952_RS18265	COG0745	RESPONSE REGULATOR receiver
KP952_RS18275	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KP952_RS18280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KP952_RS18285	COG1481	regulation of sporulation
KP952_RS18290	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KP952_RS18295	COG1660	Displays ATPase and GTPase activities
KP952_RS18300	COG1051	belongs to the nudix hydrolase family
KP952_RS18305	COG0492	ferredoxin-NADP+ reductase activity
KP952_RS18310	COG0791	NLP P60 protein
KP952_RS18310	COG3883	PFAM NLP P60 protein
KP952_RS18315	COG0457	Tetratricopeptide repeat
KP952_RS18320	COG1132	(ABC) transporter
KP952_RS18340	COG0140	phosphoribosyl-ATP diphosphatase activity
KP952_RS18340	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KP952_RS18345	COG0107	imidazoleglycerol-phosphate synthase activity
KP952_RS18350	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KP952_RS18355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KP952_RS18360	COG0131	Imidazoleglycerol-phosphate dehydratase
KP952_RS18365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KP952_RS18370	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KP952_RS18375	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KP952_RS18380	COG4990	cell redox homeostasis
KP952_RS18385	COG5297	Belongs to the glycosyl hydrolase family 6
KP952_RS18395	COG0110	maltose O-acetyltransferase activity
KP952_RS18400	COG0546	phosphoglycolate phosphatase activity
KP952_RS18405	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KP952_RS18410	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KP952_RS18415	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KP952_RS18420	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KP952_RS18425	COG0363	glucosamine-6-phosphate deaminase activity
KP952_RS18430	COG2188	Transcriptional regulator
KP952_RS18435	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KP952_RS18445	COG1950	PFAM Membrane protein of
KP952_RS18450	COG1983	PspC domain protein
KP952_RS18455	COG3595	metallopeptidase activity
KP952_RS18470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KP952_RS18475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KP952_RS18480	COG0556	nucleotide-excision repair
KP952_RS18485	COG4897	Protein conserved in bacteria
KP952_RS18490	COG3848	Pyruvate phosphate dikinase
KP952_RS18490	COG0574	Belongs to the PEP-utilizing enzyme family
KP952_RS18495	COG1309	transcriptional regulator
KP952_RS18500	COG2814	Major facilitator Superfamily
KP952_RS18505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KP952_RS18515	COG0793	Belongs to the peptidase S41A family
KP952_RS18515	COG3409	Peptidoglycan-binding domain 1 protein
KP952_RS18520	COG2177	Part of the ABC transporter FtsEX involved in
KP952_RS18525	COG2884	Cell division ATP-binding protein ftsE
KP952_RS18530	COG2010	Cytochrome c
KP952_RS18535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KP952_RS18545	COG0653	protein targeting
KP952_RS18550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KP952_RS18565	COG1516	flagellar protein fliS
KP952_RS18570	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KP952_RS18575	COG1334	flagellar protein FlaG
KP952_RS18580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KP952_RS18585	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KP952_RS18590	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KP952_RS18600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KP952_RS18605	COG4786	Flagellar basal body rod
KP952_RS18605	COG1256	bacterial-type flagellum assembly
KP952_RS18610	COG3418	PFAM FlgN family protein
KP952_RS18615	COG2747	anti-sigma28 factor FlgM
KP952_RS18625	COG1040	competence protein
KP952_RS18635	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KP952_RS18640	COG1307	EDD domain protein, DegV family
KP952_RS18645	COG2197	response regulator
KP952_RS18650	COG4585	Histidine kinase
KP952_RS18655	COG1739	Uncharacterized protein family UPF0029
KP952_RS18690	COG1131	(ABC) transporter
KP952_RS18700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KP952_RS18705	COG0438	transferase activity, transferring glycosyl groups
KP952_RS18710	COG1215	transferase activity, transferring glycosyl groups
KP952_RS18715	COG3206	protein involved in exopolysaccharide biosynthesis
KP952_RS18720	COG3307	-O-antigen
KP952_RS18725	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KP952_RS18730	COG0297	glycogen (starch) synthase activity
KP952_RS18730	COG0438	transferase activity, transferring glycosyl groups
KP952_RS18735	COG2244	polysaccharide biosynthetic process
KP952_RS18750	COG2247	cell wall binding repeat
KP952_RS18750	COG0860	N-Acetylmuramoyl-L-alanine amidase
KP952_RS18755	COG2247	cell wall binding repeat
KP952_RS18755	COG2385	sporulation resulting in formation of a cellular spore
KP952_RS18780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KP952_RS18785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KP952_RS18800	COG1682	transport, permease protein
KP952_RS18815	COG0463	Glycosyl transferase, family 2
KP952_RS18815	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KP952_RS18820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KP952_RS18825	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KP952_RS18830	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KP952_RS18835	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KP952_RS18840	COG4193	domain, Protein
KP952_RS18845	COG1482	cell wall glycoprotein biosynthetic process
KP952_RS18850	COG0697	spore germination
KP952_RS18855	COG0814	amino acid
KP952_RS18870	COG1316	TRANSCRIPTIONal
KP952_RS18875	COG0561	phosphatase activity
KP952_RS18880	COG0791	NLP P60 protein
KP952_RS18890	COG2843	Capsule synthesis protein
KP952_RS18900	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KP952_RS18905	COG1609	Transcriptional regulator
KP952_RS18910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KP952_RS18915	COG1869	D-ribose catabolic process
KP952_RS18920	COG1129	ABC transporter
KP952_RS18925	COG1172	Belongs to the binding-protein-dependent transport system permease family
KP952_RS18930	COG1879	ABC-type sugar transport system periplasmic component
KP952_RS18935	COG3103	Sh3 type 3 domain protein
KP952_RS18945	COG2249	NAD(P)H dehydrogenase (quinone) activity
KP952_RS18950	COG3527	Alpha-acetolactate decarboxylase
KP952_RS18955	COG0028	Belongs to the TPP enzyme family
KP952_RS18960	COG0583	DNA-binding transcription factor activity
KP952_RS18980	COG5337	Spore coat protein CotH
KP952_RS18990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KP952_RS19000	COG0405	Gamma-glutamyltransferase
KP952_RS19005	COG1522	sequence-specific DNA binding
KP952_RS19010	COG2059	Chromate
KP952_RS19015	COG2059	Chromate
KP952_RS19025	COG0655	NAD(P)H dehydrogenase (quinone) activity
KP952_RS19030	COG0583	DNA-binding transcription factor activity
KP952_RS19085	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KP952_RS19090	COG4464	protein tyrosine phosphatase activity
KP952_RS19095	COG0489	protein tyrosine kinase activity
KP952_RS19100	COG3944	biosynthesis protein
KP952_RS19110	COG4715	Zinc finger, swim domain protein
KP952_RS19115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KP952_RS19120	COG0561	phosphatase activity
KP952_RS19125	COG1349	DNA-binding transcription factor activity
KP952_RS19130	COG0629	single-stranded DNA binding
KP952_RS19160	COG1970	mechanosensitive ion channel activity
KP952_RS19165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KP952_RS19170	COG0457	Tetratricopeptide repeat
KP952_RS19175	COG4786	Flagellar basal body rod
KP952_RS19180	COG4786	Flagellar basal body rod
KP952_RS19185	COG1077	Cell shape determining protein MreB Mrl
KP952_RS19190	COG1609	Transcriptional regulator
KP952_RS19200	COG1846	Transcriptional regulator
KP952_RS19205	COG2814	Major facilitator Superfamily
KP952_RS19210	COG3420	alginic acid biosynthetic process
KP952_RS19215	COG1953	Uracil, thiamine, allantoin
KP952_RS19220	COG0477	Major facilitator Superfamily
KP952_RS19225	COG1335	isochorismatase
KP952_RS19235	COG0004	ammonium transporteR
KP952_RS19240	COG0347	Belongs to the P(II) protein family
KP952_RS19245	COG0671	phosphoesterase, PA-phosphatase related
KP952_RS19255	COG0739	heme binding
KP952_RS19260	COG1247	-acetyltransferase
KP952_RS19270	COG2089	acid synthase
KP952_RS19280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KP952_RS19285	COG0789	Transcriptional regulator
KP952_RS19300	COG1959	2 iron, 2 sulfur cluster binding
KP952_RS19305	COG0804	urea catabolic process
KP952_RS19310	COG0832	Belongs to the urease beta subunit family
KP952_RS19315	COG0831	urea catabolic process
KP952_RS19330	COG3237	CsbD-like
KP952_RS19335	COG1994	Peptidase M50
KP952_RS19340	COG0457	Tetratricopeptide repeat
KP952_RS19345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KP952_RS19350	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KP952_RS19360	COG2304	oxidoreductase activity
KP952_RS19370	COG2304	oxidoreductase activity
KP952_RS19375	COG2385	sporulation resulting in formation of a cellular spore
KP952_RS19380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KP952_RS19390	COG4836	Membrane
KP952_RS19400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KP952_RS19405	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KP952_RS19410	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KP952_RS19415	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KP952_RS19420	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KP952_RS19425	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KP952_RS19435	COG0356	it plays a direct role in the translocation of protons across the membrane
KP952_RS19445	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KP952_RS19450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KP952_RS19455	COG4475	Protein of unknown function (DUF436)
KP952_RS19460	COG0698	ribose 5-phosphate isomerase
KP952_RS19465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KP952_RS19470	COG1971	Probably functions as a manganese efflux pump
KP952_RS19475	COG0009	L-threonylcarbamoyladenylate synthase
KP952_RS19480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KP952_RS19500	COG2890	protein-(glutamine-N5) methyltransferase activity
KP952_RS19505	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KP952_RS19510	COG0346	lactoylglutathione lyase activity
KP952_RS19515	COG0789	Transcriptional regulator
KP952_RS19520	COG0679	Auxin Efflux Carrier
KP952_RS19525	COG0281	malic enzyme
KP952_RS19530	COG1435	thymidine kinase activity
KP952_RS19540	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KP952_RS19550	COG1494	fructose-1,6-bisphosphatase
KP952_RS19555	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KP952_RS19565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KP952_RS19570	COG0191	fructose-bisphosphate aldolase activity
KP952_RS19575	COG2204	response regulator
KP952_RS19580	COG4821	SIS domain
KP952_RS19585	COG0504	CTP synthase activity
KP952_RS19590	COG3343	RNA polymerase activity
KP952_RS19595	COG1960	acyl-CoA dehydrogenase activity
KP952_RS19600	COG0247	lactate metabolic process
KP952_RS19600	COG2181	nitrate reductase activity
KP952_RS19605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KP952_RS19610	COG4294	response to UV
KP952_RS19620	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KP952_RS19630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KP952_RS19640	COG2181	nitrate reductase activity
KP952_RS19645	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KP952_RS19650	COG1140	nitrate reductase beta subunit
KP952_RS19655	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KP952_RS19660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KP952_RS19670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KP952_RS19675	COG2223	nitrite transmembrane transporter activity
KP952_RS19680	COG0018	arginyl-trna synthetase
KP952_RS19685	COG4506	Protein conserved in bacteria
KP952_RS19700	COG0535	radical SAM domain protein
KP952_RS19710	COG1131	(ABC) transporter
KP952_RS19715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KP952_RS19720	COG0612	Peptidase, M16
KP952_RS19725	COG0612	Peptidase, M16
KP952_RS19735	COG3391	amine dehydrogenase activity
KP952_RS19745	COG0457	Tetratricopeptide repeat
KP952_RS19760	COG0010	Belongs to the arginase family
KP952_RS19765	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KP952_RS19770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KP952_RS19785	COG1994	Peptidase M50
KP952_RS19790	COG1942	4-Oxalocrotonate Tautomerase
KP952_RS19795	COG1846	Transcriptional regulator
KP952_RS19800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KP952_RS19805	COG0477	Major facilitator Superfamily
KP952_RS19810	COG1959	2 iron, 2 sulfur cluster binding
KP952_RS19815	COG3465	dGTPase activity
KP952_RS19820	COG1078	dGTPase activity
KP952_RS19825	COG4844	belongs to the
KP952_RS19835	COG0697	spore germination
KP952_RS19840	COG0095	Lipoate-protein ligase
KP952_RS19845	COG0583	DNA-binding transcription factor activity
KP952_RS19850	COG0280	phosphate acetyltransferase
KP952_RS19855	COG3253	May function as heme-dependent peroxidase
KP952_RS19860	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS19865	COG0436	Aminotransferase
KP952_RS19870	COG2814	Major facilitator Superfamily
KP952_RS19875	COG0151	Belongs to the GarS family
KP952_RS19880	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS19885	COG1917	Cupin 2, conserved barrel domain protein
KP952_RS19890	COG0077	Prephenate dehydratase
KP952_RS19895	COG2814	Major facilitator Superfamily
KP952_RS19900	COG0833	amino acid
KP952_RS19905	COG4187	Peptidase family M20/M25/M40
KP952_RS19910	COG1012	belongs to the aldehyde dehydrogenase family
KP952_RS19915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KP952_RS19925	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KP952_RS19930	COG1091	dTDP-4-dehydrorhamnose reductase activity
KP952_RS19935	COG1088	dTDP-glucose 4,6-dehydratase activity
KP952_RS19940	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KP952_RS19945	COG3980	spore coat polysaccharide biosynthesis protein
KP952_RS19950	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KP952_RS19955	COG2089	acid synthase
KP952_RS19960	COG0456	acetyltransferase
KP952_RS19965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KP952_RS19970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KP952_RS19975	COG0463	Glycosyl transferase, family 2
KP952_RS19985	COG2363	Small membrane protein
KP952_RS19990	COG2233	PERMEase
KP952_RS20000	COG1012	belongs to the aldehyde dehydrogenase family
KP952_RS20005	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KP952_RS20010	COG1216	Glycosyl transferase, family 2
KP952_RS20015	COG0351	phosphomethylpyrimidine kinase
KP952_RS20025	COG1621	beta-fructofuranosidase activity
KP952_RS20030	COG1263	PTS System
KP952_RS20030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KP952_RS20035	COG2116	formate transmembrane transporter activity
KP952_RS20040	COG3711	transcriptional antiterminator
KP952_RS20050	COG1404	Belongs to the peptidase S8 family
KP952_RS20055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KP952_RS20060	COG0778	Nitroreductase
KP952_RS20065	COG0772	Belongs to the SEDS family
KP952_RS20080	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KP952_RS20085	COG1845	cytochrome c oxidase, subunit III
KP952_RS20090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KP952_RS20095	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KP952_RS20100	COG2261	transglycosylase associated protein
KP952_RS20105	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KP952_RS20110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KP952_RS20115	COG2246	polysaccharide biosynthetic process
KP952_RS20120	COG1309	transcriptional regulator
KP952_RS20130	COG3162	membrane
KP952_RS20135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KP952_RS20140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KP952_RS20145	COG2837	iron assimilation
KP952_RS20150	COG2822	iron ion transport
KP952_RS20155	COG0672	)-iron permease
KP952_RS20160	COG0352	thiamine-phosphate diphosphorylase activity
KP952_RS20165	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KP952_RS20170	COG0583	DNA-binding transcription factor activity
KP952_RS20175	COG1380	Effector of murein hydrolase LrgA
KP952_RS20180	COG1346	cytolysis
KP952_RS20185	COG2814	Major facilitator Superfamily
KP952_RS20190	COG4895	conserved protein (DUF2196)
KP952_RS20195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KP952_RS20200	COG0346	lactoylglutathione lyase activity
KP952_RS20215	COG1404	Belongs to the peptidase S8 family
KP952_RS20220	COG1263	PTS System
KP952_RS20220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KP952_RS20225	COG3711	transcriptional antiterminator
KP952_RS20230	COG1442	glycosyl transferase family 8
KP952_RS20235	COG5522	Integral membrane protein (intg_mem_TP0381)
KP952_RS20240	COG1846	Transcriptional regulator
KP952_RS20245	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KP952_RS20250	COG2234	aminopeptidase activity
KP952_RS20255	COG2357	RelA SpoT domain protein
KP952_RS20265	COG1575	Belongs to the MenA family. Type 1 subfamily
KP952_RS20280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KP952_RS20285	COG1696	Membrane protein involved in D-alanine export
KP952_RS20290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KP952_RS20295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KP952_RS20305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KP952_RS20310	COG1486	melibiose metabolic process
KP952_RS20315	COG1447	Phosphotransferase system cellobiose-specific component IIA
KP952_RS20320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KP952_RS20325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KP952_RS20330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KP952_RS20330	COG3711	transcriptional antiterminator
KP952_RS20340	COG2094	Belongs to the DNA glycosylase MPG family
KP952_RS20345	COG0753	catalase activity
KP952_RS20350	COG2814	Major facilitator Superfamily
KP952_RS20355	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KP952_RS20360	COG1131	(ABC) transporter
KP952_RS20380	COG1595	DNA-templated transcription, initiation
KP952_RS20385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KP952_RS20390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KP952_RS20395	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KP952_RS20400	COG4988	ABC transporter
KP952_RS20405	COG1294	oxidase, subunit
KP952_RS20410	COG1271	oxidase subunit
KP952_RS20415	COG3493	citrate carrier protein
KP952_RS20430	COG0726	polysaccharide deacetylase
KP952_RS20435	COG3842	ATPase activity
KP952_RS20440	COG2508	Transcriptional regulator
KP952_RS20445	COG1012	belongs to the aldehyde dehydrogenase family
KP952_RS20450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KP952_RS20455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KP952_RS20465	COG4585	Histidine kinase
KP952_RS20470	COG2197	response regulator
KP952_RS20475	COG2195	Cleaves the N-terminal amino acid of tripeptides
KP952_RS20485	COG4894	glucomannan catabolic process
KP952_RS20490	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KP952_RS20495	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KP952_RS20500	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS20505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KP952_RS20510	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KP952_RS20515	COG2610	gluconate transmembrane transporter activity
KP952_RS20520	COG0500	methyltransferase
KP952_RS20525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KP952_RS20540	COG0693	protein deglycase activity
KP952_RS20540	COG0753	catalase activity
KP952_RS20545	COG2851	Citrate transporter
KP952_RS20550	COG2273	Hydrolase Family 16
KP952_RS20555	COG3711	transcriptional antiterminator
KP952_RS20565	COG2270	Major facilitator Superfamily
KP952_RS20570	COG0513	Belongs to the DEAD box helicase family
KP952_RS20575	COG2755	lipolytic protein G-D-S-L family
KP952_RS20575	COG3401	FG-GAP repeat protein
KP952_RS20705	COG0589	response to stress
KP952_RS20715	COG2190	(PTS) system
KP952_RS20715	COG1263	PTS System
KP952_RS20715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KP952_RS20735	COG5444	nuclease activity
KP952_RS20755	COG0494	nUDIX hydrolase
KP952_RS20760	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
KP952_RS20765	COG3507	Belongs to the glycosyl hydrolase 43 family
KP952_RS20780	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KP952_RS20785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KP952_RS20790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KP952_RS20795	COG2390	Transcriptional regulator
KP952_RS20810	COG2079	MmgE PrpD family protein
KP952_RS20815	COG1473	amidohydrolase
KP952_RS20820	COG1126	abc transporter atp-binding protein
KP952_RS20825	COG0765	amino acid transport
KP952_RS20830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KP952_RS20835	COG0456	acetyltransferase
KP952_RS20840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KP952_RS20845	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KP952_RS20850	COG0561	phosphatase activity
KP952_RS20880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KP952_RS20885	COG5294	Protein conserved in bacteria
KP952_RS20900	COG2205	protein histidine kinase activity
KP952_RS20905	COG0745	RESPONSE REGULATOR receiver
KP952_RS20910	COG0191	fructose-bisphosphate aldolase activity
KP952_RS20915	COG1082	Xylose isomerase domain protein TIM barrel
KP952_RS20920	COG1082	Xylose isomerase domain protein TIM barrel
KP952_RS20925	COG0673	inositol 2-dehydrogenase activity
KP952_RS20935	COG1082	Xylose isomerase domain protein TIM barrel
KP952_RS20940	COG3962	Belongs to the TPP enzyme family
KP952_RS20945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KP952_RS20965	COG1349	DNA-binding transcription factor activity
KP952_RS20970	COG0667	Aldo Keto reductase
KP952_RS21000	COG0326	Molecular chaperone. Has ATPase activity
KP952_RS21055	COG1917	Cupin 2, conserved barrel domain protein
KP952_RS21060	COG1309	transcriptional regulator
KP952_RS21065	COG1028	Short-chain dehydrogenase reductase Sdr
KP952_RS21070	COG1846	Transcriptional regulator
KP952_RS21075	COG1380	Effector of murein hydrolase LrgA
KP952_RS21080	COG1346	cytolysis
KP952_RS21085	COG5039	Polysaccharide pyruvyl transferase
KP952_RS21090	COG1929	Belongs to the glycerate kinase type-1 family
KP952_RS21095	COG1802	Transcriptional regulator
KP952_RS21100	COG1070	Carbohydrate kinase
KP952_RS21105	COG2610	gluconate transmembrane transporter activity
KP952_RS21110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KP952_RS21115	COG0450	alkyl hydroperoxide reductase
KP952_RS21120	COG3634	alkyl hydroperoxide reductase activity
KP952_RS21125	COG2723	6-phospho-beta-galactosidase activity
KP952_RS21135	COG2188	Transcriptional regulator
KP952_RS21145	COG1131	(ABC) transporter
KP952_RS21150	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
KP952_RS21165	COG0071	Belongs to the small heat shock protein (HSP20) family
KP952_RS21195	COG0210	DNA helicase
KP952_RS21225	COG2963	transposase activity
KP952_RS21260	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KP952_RS21275	COG1063	alcohol dehydrogenase
KP952_RS21295	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KP952_RS21305	COG0457	Tetratricopeptide repeat
KP952_RS21315	COG0010	Belongs to the arginase family
KP952_RS21320	COG0833	amino acid
KP952_RS21325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KP952_RS21345	COG5658	integral membrane protein
KP952_RS21350	COG0640	Transcriptional regulator
KP952_RS21355	COG3829	transcription factor binding
KP952_RS21370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KP952_RS21375	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KP952_RS21380	COG4853	Protein conserved in bacteria
KP952_RS21385	COG4863	YycH protein
KP952_RS21390	COG5002	protein histidine kinase activity
KP952_RS21395	COG0745	RESPONSE REGULATOR receiver
KP952_RS21425	COG0346	lactoylglutathione lyase activity
KP952_RS21430	COG0305	Participates in initiation and elongation during chromosome replication
KP952_RS21445	COG3093	addiction module antidote protein HigA
KP952_RS21450	COG2807	transmembrane transport
KP952_RS21455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KP952_RS21460	COG0359	binds to the 23S rRNA
KP952_RS21465	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KP952_RS21470	COG4241	membrane
KP952_RS21485	COG1733	regulation of RNA biosynthetic process
KP952_RS21490	COG1227	inorganic diphosphatase activity
KP952_RS21510	COG0789	Transcriptional regulator
KP952_RS21510	COG4978	Transcriptional regulator
KP952_RS21520	COG4319	ketosteroid isomerase
KP952_RS21525	COG1357	PFAM Pentapeptide repeats (8 copies)
KP952_RS21540	COG1846	Transcriptional regulator
KP952_RS21545	COG2153	protein acetylation
KP952_RS21550	COG2364	Membrane
KP952_RS21565	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KP952_RS21575	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KP952_RS21580	COG1331	Highly conserved protein containing a thioredoxin domain
KP952_RS21585	COG1266	CAAX protease self-immunity
KP952_RS21590	COG0477	Major facilitator Superfamily
KP952_RS21590	COG2814	Major facilitator Superfamily
KP952_RS21595	COG0346	lactoylglutathione lyase activity
KP952_RS21600	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KP952_RS21605	COG0542	response to heat
KP952_RS21620	COG0708	Exodeoxyribonuclease III
KP952_RS21625	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KP952_RS21630	COG0629	single-stranded DNA binding
KP952_RS21635	COG0360	Binds together with S18 to 16S ribosomal RNA
KP952_RS21640	COG0012	GTP binding
KP952_RS21645	COG0243	molybdopterin cofactor binding
KP952_RS21650	COG4481	Protein conserved in bacteria
KP952_RS21655	COG3949	Membrane
KP952_RS21665	COG1475	DNA binding
KP952_RS21670	COG1192	Involved in chromosome partitioning
KP952_RS21680	COG1475	DNA binding
KP952_RS21685	COG0357	Ribosomal RNA small subunit methyltransferase G
KP952_RS21690	COG0445	tRNA wobble uridine modification
KP952_RS21695	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KP952_RS21700	COG1847	R3H domain protein
KP952_RS21705	COG0706	membrane insertase activity
KP952_RS21710	COG0594	ribonuclease P activity
KP952_RS21770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KP952_RS22050	COG0697	spore germination
KP952_RS22060	COG2190	(PTS) system