locus-tag	class	description
D9C14_RS00010	COG1942	4-Oxalocrotonate Tautomerase
D9C14_RS00015	COG0583	DNA-binding transcription factor activity
D9C14_RS00025	COG1114	Component of the transport system for branched-chain amino acids
D9C14_RS00030	COG1687	branched-chain amino acid
D9C14_RS00035	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D9C14_RS00040	COG1522	sequence-specific DNA binding
D9C14_RS00050	COG2124	cytochrome p450
D9C14_RS00060	COG1335	isochorismatase
D9C14_RS00075	COG2318	DinB family
D9C14_RS00085	COG2070	2-Nitropropane dioxygenase
D9C14_RS00095	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9C14_RS00105	COG2186	Transcriptional regulator
D9C14_RS00120	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS00125	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9C14_RS00130	COG3959	Transketolase, thiamine diphosphate binding domain
D9C14_RS00145	COG0789	Transcriptional regulator
D9C14_RS00145	COG4978	Transcriptional regulator
D9C14_RS00150	COG2315	Protein conserved in bacteria
D9C14_RS00160	COG3443	Belongs to the bacterial solute-binding protein 9 family
D9C14_RS00165	COG1595	DNA-templated transcription, initiation
D9C14_RS00170	COG0667	Aldo Keto reductase
D9C14_RS00175	COG2851	Citrate transporter
D9C14_RS00180	COG0583	DNA-binding transcription factor activity
D9C14_RS00185	COG2828	Protein conserved in bacteria
D9C14_RS00190	COG3409	Peptidoglycan-binding domain 1 protein
D9C14_RS00195	COG5566	PFAM Mor transcription activator
D9C14_RS00200	COG0596	Alpha beta hydrolase
D9C14_RS00205	COG4991	sh3 domain protein
D9C14_RS00210	COG4991	sh3 domain protein
D9C14_RS00220	COG0346	lactoylglutathione lyase activity
D9C14_RS00230	COG5577	PFAM Coat F domain
D9C14_RS00235	COG1063	alcohol dehydrogenase
D9C14_RS00245	COG5577	PFAM Coat F domain
D9C14_RS00250	COG0789	Transcriptional regulator
D9C14_RS00260	COG1064	alcohol dehydrogenase
D9C14_RS00265	COG0693	protein deglycase activity
D9C14_RS00270	COG1621	beta-fructofuranosidase activity
D9C14_RS00275	COG3716	PTS system mannose fructose sorbose family IID component
D9C14_RS00280	COG3715	PTS system
D9C14_RS00285	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C14_RS00290	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C14_RS00295	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9C14_RS00295	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D9C14_RS00305	COG1113	amino acid transport
D9C14_RS00310	COG1280	lysine exporter protein (LysE YggA)
D9C14_RS00315	COG1378	Sugar-specific transcriptional regulator TrmB
D9C14_RS00320	COG1595	DNA-templated transcription, initiation
D9C14_RS00340	COG2124	cytochrome p450
D9C14_RS00340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C14_RS00345	COG1309	transcriptional regulator
D9C14_RS00350	COG2226	methyltransferase
D9C14_RS00365	COG2116	formate transmembrane transporter activity
D9C14_RS00370	COG5609	conserved protein (DUF2294)
D9C14_RS00375	COG3383	formate dehydrogenase (NAD+) activity
D9C14_RS00380	COG2427	Protein of unknown function (DUF1641)
D9C14_RS00390	COG0626	cystathionine gamma-synthase activity
D9C14_RS00395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C14_RS00400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D9C14_RS00405	COG2226	methyltransferase
D9C14_RS00420	COG0768	penicillin binding
D9C14_RS00425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D9C14_RS00430	COG0572	uridine kinase
D9C14_RS00435	COG0826	peptidase U32
D9C14_RS00440	COG0826	peptidase U32
D9C14_RS00445	COG4122	O-methyltransferase activity
D9C14_RS00450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9C14_RS00455	COG3906	Belongs to the UPF0473 family
D9C14_RS00460	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D9C14_RS00465	COG4472	Bacterial protein of unknown function (DUF965)
D9C14_RS00470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9C14_RS00475	COG0628	permease
D9C14_RS00480	COG1126	abc transporter atp-binding protein
D9C14_RS00485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C14_RS00490	COG0765	amino acid transport
D9C14_RS00495	COG0765	amino acid transport
D9C14_RS00510	COG3881	PFAM PRC-barrel domain
D9C14_RS00515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9C14_RS00520	COG0457	Tetratricopeptide repeat
D9C14_RS00525	COG0482	sulfurtransferase activity
D9C14_RS00530	COG1104	cysteine desulfurase activity
D9C14_RS00535	COG1959	2 iron, 2 sulfur cluster binding
D9C14_RS00540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D9C14_RS00545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D9C14_RS00555	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D9C14_RS00560	COG0124	histidyl-tRNA synthetase
D9C14_RS00570	COG4991	sh3 domain protein
D9C14_RS00570	COG3103	Sh3 type 3 domain protein
D9C14_RS00570	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C14_RS00575	COG1490	D-aminoacyl-tRNA deacylase activity
D9C14_RS00580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D9C14_RS00585	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C14_RS00590	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D9C14_RS00590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9C14_RS00595	COG5416	Lipopolysaccharide assembly protein A domain
D9C14_RS00600	COG0490	domain, Protein
D9C14_RS00605	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9C14_RS00605	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9C14_RS00615	COG2244	polysaccharide biosynthetic process
D9C14_RS00620	COG2323	membrane
D9C14_RS00630	COG1862	Preprotein translocase
D9C14_RS00635	COG0343	queuine tRNA-ribosyltransferase activity
D9C14_RS00640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D9C14_RS00650	COG2255	four-way junction helicase activity
D9C14_RS00655	COG0632	four-way junction helicase activity
D9C14_RS00665	COG2814	Major facilitator Superfamily
D9C14_RS00670	COG0673	inositol 2-dehydrogenase activity
D9C14_RS00675	COG2112	serine threonine protein kinase
D9C14_RS00695	COG1115	amino acid carrier protein
D9C14_RS00700	COG0217	transcriptional regulatory protein
D9C14_RS00710	COG1388	LysM domain
D9C14_RS00715	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D9C14_RS00720	COG0157	Belongs to the NadC ModD family
D9C14_RS00725	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D9C14_RS00730	COG1104	cysteine desulfurase activity
D9C14_RS00735	COG1827	regulation of RNA biosynthetic process
D9C14_RS00740	COG0077	Prephenate dehydratase
D9C14_RS00745	COG4492	Belongs to the UPF0735 family
D9C14_RS00750	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D9C14_RS00755	COG3290	protein histidine kinase activity
D9C14_RS00765	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D9C14_RS00770	COG2868	ribosomal protein
D9C14_RS00775	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D9C14_RS00780	COG1994	Peptidase M50
D9C14_RS00785	COG0739	heme binding
D9C14_RS00790	COG2894	cell division
D9C14_RS00795	COG0850	regulation of cytokinetic process
D9C14_RS00800	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D9C14_RS00810	COG1077	Cell shape determining protein MreB Mrl
D9C14_RS00815	COG2003	Belongs to the UPF0758 family
D9C14_RS00820	COG0424	maF-like protein
D9C14_RS00830	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D9C14_RS00835	COG0285	dihydrofolate synthase activity
D9C14_RS00840	COG0525	valine-tRNA ligase activity
D9C14_RS00850	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C14_RS00855	COG1388	LysM domain
D9C14_RS00860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9C14_RS00865	COG0113	porphobilinogen synthase activity
D9C14_RS00870	COG1587	Uroporphyrinogen-III synthase
D9C14_RS00875	COG0181	hydroxymethylbilane synthase activity
D9C14_RS00880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9C14_RS00885	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D9C14_RS00895	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D9C14_RS00900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D9C14_RS00905	COG0470	DNA polymerase III
D9C14_RS00905	COG1067	ATP-dependent peptidase activity
D9C14_RS00910	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D9C14_RS00915	COG0544	peptidyl-prolyl cis-trans isomerase activity
D9C14_RS00920	COG0457	Tetratricopeptide repeat
D9C14_RS00920	COG1477	protein flavinylation
D9C14_RS00925	COG0066	3-isopropylmalate dehydratase activity
D9C14_RS00930	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D9C14_RS00935	COG0473	3-isopropylmalate dehydrogenase activity
D9C14_RS00940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9C14_RS00945	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D9C14_RS00950	COG0440	acetolactate synthase activity
D9C14_RS00955	COG0028	Belongs to the TPP enzyme family
D9C14_RS00965	COG0454	-acetyltransferase
D9C14_RS00970	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
D9C14_RS00980	COG0622	Phosphoesterase
D9C14_RS00985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D9C14_RS00990	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D9C14_RS00995	COG5401	PFAM Sporulation and spore germination
D9C14_RS01000	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9C14_RS01005	COG1846	Transcriptional regulator
D9C14_RS01015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9C14_RS01035	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C14_RS01035	COG3409	Peptidoglycan-binding domain 1 protein
D9C14_RS01035	COG1388	LysM domain
D9C14_RS01095	COG0791	NLP P60 protein
D9C14_RS01095	COG1388	LysM domain
D9C14_RS01100	COG3953	SLT domain
D9C14_RS01100	COG5280	Phage tail tape measure protein TP901
D9C14_RS01165	COG5484	DNA packaging
D9C14_RS01190	COG1595	DNA-templated transcription, initiation
D9C14_RS01250	COG1484	DNA-dependent DNA replication
D9C14_RS01255	COG3935	DnaD domain protein
D9C14_RS01260	COG3723	Recombinational DNA repair protein, rece pathway
D9C14_RS01265	COG5377	YqaJ viral recombinase family
D9C14_RS01295	COG3646	Phage regulatory protein
D9C14_RS01295	COG3645	SOS response
D9C14_RS01305	COG3620	sequence-specific DNA binding
D9C14_RS01315	COG2856	Zn peptidase
D9C14_RS01320	COG2197	response regulator
D9C14_RS01325	COG0824	Thioesterase
D9C14_RS01330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D9C14_RS01335	COG1053	succinate dehydrogenase
D9C14_RS01340	COG2009	succinate dehydrogenase
D9C14_RS01345	COG1719	4-vinyl reductase, 4VR
D9C14_RS01350	COG0527	aspartate kinase activity
D9C14_RS01360	COG0322	excinuclease ABC activity
D9C14_RS01365	COG3118	belongs to the thioredoxin family
D9C14_RS01375	COG3534	alpha-L-arabinofuranosidase
D9C14_RS01380	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D9C14_RS01385	COG2086	electron transfer activity
D9C14_RS01390	COG1024	Enoyl-CoA hydratase
D9C14_RS01395	COG1309	transcriptional regulator
D9C14_RS01400	COG0318	PFAM AMP-dependent synthetase and ligase
D9C14_RS01405	COG3766	membrane
D9C14_RS01410	COG1193	negative regulation of DNA recombination
D9C14_RS01415	COG1796	DNA polymerase
D9C14_RS01415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9C14_RS01420	COG1286	toxin biosynthetic process
D9C14_RS01425	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D9C14_RS01430	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9C14_RS01435	COG0072	phenylalanine-tRNA ligase activity
D9C14_RS01435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C14_RS01440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D9C14_RS01450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9C14_RS01460	COG3835	regulator
D9C14_RS01465	COG0277	FAD linked oxidase domain protein
D9C14_RS01470	COG0247	lactate metabolic process
D9C14_RS01475	COG0346	lactoylglutathione lyase activity
D9C14_RS01485	COG1966	Carbon starvation protein
D9C14_RS01490	COG3534	alpha-L-arabinofuranosidase
D9C14_RS01495	COG0395	ABC-type sugar transport system, permease component
D9C14_RS01500	COG1175	transmembrane transport
D9C14_RS01505	COG1653	transport
D9C14_RS01510	COG0371	Dehydrogenase
D9C14_RS01515	COG0647	UMP catabolic process
D9C14_RS01520	COG0235	Class ii aldolase
D9C14_RS01525	COG1069	ribulokinase activity
D9C14_RS01530	COG2160	L-arabinose isomerase activity
D9C14_RS01535	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C14_RS01540	COG1363	Peptidase, m42
D9C14_RS01550	COG3326	Membrane
D9C14_RS01555	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D9C14_RS01560	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D9C14_RS01565	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D9C14_RS01575	COG1346	cytolysis
D9C14_RS01580	COG1380	Effector of murein hydrolase LrgA
D9C14_RS01585	COG3279	Response regulator of the LytR AlgR family
D9C14_RS01590	COG3275	phosphorelay sensor kinase activity
D9C14_RS01595	COG1011	Hydrolase
D9C14_RS01600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9C14_RS01610	COG0398	Pfam SNARE associated Golgi protein
D9C14_RS01615	COG1484	DNA-dependent DNA replication
D9C14_RS01620	COG3611	Membrane attachment protein
D9C14_RS01625	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D9C14_RS01630	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D9C14_RS01635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9C14_RS01640	COG1733	regulation of RNA biosynthetic process
D9C14_RS01645	COG2814	Major facilitator Superfamily
D9C14_RS01650	COG0656	L-ascorbic acid biosynthetic process
D9C14_RS01655	COG0237	dephospho-CoA kinase activity
D9C14_RS01660	COG1971	Probably functions as a manganese efflux pump
D9C14_RS01665	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9C14_RS01670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C14_RS01670	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C14_RS01675	COG5002	protein histidine kinase activity
D9C14_RS01680	COG0745	RESPONSE REGULATOR receiver
D9C14_RS01685	COG0039	L-malate dehydrogenase activity
D9C14_RS01690	COG0538	isocitrate dehydrogenase activity
D9C14_RS01695	COG0372	Belongs to the citrate synthase family
D9C14_RS01700	COG2707	UPF0756 membrane protein
D9C14_RS01705	COG0628	permease
D9C14_RS01710	COG3030	protein affecting phage T7 exclusion by the F plasmid
D9C14_RS01715	COG0469	pyruvate kinase activity
D9C14_RS01720	COG0205	6-phosphofructokinase activity
D9C14_RS01725	COG0825	malonyl-CoA metabolic process
D9C14_RS01730	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D9C14_RS01735	COG0281	malic enzyme
D9C14_RS01740	COG0587	DNA-directed DNA polymerase activity
D9C14_RS01760	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D9C14_RS01770	COG4109	DRTGG domain
D9C14_RS01775	COG0730	response to heat
D9C14_RS01780	COG1473	amidohydrolase
D9C14_RS01785	COG0196	riboflavin kinase activity
D9C14_RS01790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C14_RS01795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D9C14_RS01800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C14_RS01805	COG1126	abc transporter atp-binding protein
D9C14_RS01810	COG0765	amino acid transport
D9C14_RS01815	COG0765	amino acid transport
D9C14_RS01820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C14_RS01825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C14_RS01830	COG0454	-acetyltransferase
D9C14_RS01835	COG0583	DNA-binding transcription factor activity
D9C14_RS01840	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9C14_RS01845	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS01855	COG0165	Argininosuccinate lyase
D9C14_RS01860	COG0137	argininosuccinate synthase activity
D9C14_RS01865	COG0521	Mo-molybdopterin cofactor biosynthetic process
D9C14_RS01870	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D9C14_RS01880	COG0827	DNA restriction-modification system
D9C14_RS01885	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D9C14_RS01890	COG3874	Sporulation protein YtfJ
D9C14_RS01900	COG1714	RDD family
D9C14_RS01905	COG0616	signal peptide processing
D9C14_RS01910	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9C14_RS01915	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D9C14_RS01920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9C14_RS01930	COG0301	tRNA thio-modification
D9C14_RS01935	COG1104	cysteine desulfurase activity
D9C14_RS01940	COG1114	Component of the transport system for branched-chain amino acids
D9C14_RS01945	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D9C14_RS01950	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9C14_RS01955	COG1309	transcriptional regulator
D9C14_RS01960	COG1956	GAF domain-containing protein
D9C14_RS01965	COG2203	Gaf domain
D9C14_RS01965	COG2199	diguanylate cyclase activity
D9C14_RS01975	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D9C14_RS01980	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9C14_RS01985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9C14_RS01990	COG0454	-acetyltransferase
D9C14_RS01995	COG0517	IMP dehydrogenase activity
D9C14_RS02000	COG0123	including yeast histone deacetylase and acetoin utilization protein
D9C14_RS02005	COG1360	Flagellar Motor Protein
D9C14_RS02010	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9C14_RS02015	COG1609	Transcriptional regulator
D9C14_RS02020	COG1605	Chorismate mutase
D9C14_RS02020	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D9C14_RS02025	COG3118	belongs to the thioredoxin family
D9C14_RS02030	COG4980	gas vesicle protein
D9C14_RS02035	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9C14_RS02040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D9C14_RS02045	COG1674	ftsk spoiiie
D9C14_RS02050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C14_RS02055	COG4848	Belongs to the UPF0354 family
D9C14_RS02060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C14_RS02075	COG1363	Peptidase, m42
D9C14_RS02080	COG5584	Small secreted protein
D9C14_RS02085	COG0281	malic enzyme
D9C14_RS02090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C14_RS02095	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D9C14_RS02105	COG0510	thiamine kinase activity
D9C14_RS02110	COG1523	belongs to the glycosyl hydrolase 13 family
D9C14_RS02115	COG1597	lipid kinase activity
D9C14_RS02125	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9C14_RS02130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C14_RS02135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C14_RS02140	COG2252	PERMEase
D9C14_RS02145	COG4473	ABC transporter
D9C14_RS02150	COG1131	(ABC) transporter
D9C14_RS02155	COG1349	DNA-binding transcription factor activity
D9C14_RS02160	COG1187	pseudouridine synthase activity
D9C14_RS02165	COG2244	polysaccharide biosynthetic process
D9C14_RS02170	COG2081	HI0933 family
D9C14_RS02175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9C14_RS02185	COG5578	integral membrane protein
D9C14_RS02190	COG0673	inositol 2-dehydrogenase activity
D9C14_RS02195	COG1653	transport
D9C14_RS02200	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9C14_RS02205	COG4209	transmembrane transport
D9C14_RS02210	COG2207	Transcriptional regulator
D9C14_RS02215	COG1653	transport
D9C14_RS02220	COG0395	ABC-type sugar transport system, permease component
D9C14_RS02225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C14_RS02230	COG2124	cytochrome p450
D9C14_RS02235	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D9C14_RS02245	COG0156	8-amino-7-oxononanoate synthase activity
D9C14_RS02250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C14_RS02260	COG1073	alpha beta
D9C14_RS02265	COG1609	Transcriptional regulator
D9C14_RS02270	COG1653	transport
D9C14_RS02275	COG1175	transmembrane transport
D9C14_RS02280	COG0395	ABC-type sugar transport system, permease component
D9C14_RS02285	COG1486	melibiose metabolic process
D9C14_RS02290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C14_RS02295	COG0495	leucyl-tRNA aminoacylation
D9C14_RS02305	COG2202	Pas domain
D9C14_RS02305	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C14_RS02310	COG2814	Major facilitator Superfamily
D9C14_RS02315	COG2433	Pfam Transposase IS66
D9C14_RS02320	COG0577	efflux transmembrane transporter activity
D9C14_RS02325	COG1136	(ABC) transporter
D9C14_RS02330	COG2205	protein histidine kinase activity
D9C14_RS02335	COG0745	RESPONSE REGULATOR receiver
D9C14_RS02340	COG0577	efflux transmembrane transporter activity
D9C14_RS02345	COG1136	(ABC) transporter
D9C14_RS02360	COG1131	(ABC) transporter
D9C14_RS02365	COG1725	Transcriptional regulator
D9C14_RS02380	COG1242	4 iron, 4 sulfur cluster binding
D9C14_RS02385	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D9C14_RS02395	COG2267	carboxylic ester hydrolase activity
D9C14_RS02400	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D9C14_RS02405	COG1113	amino acid transport
D9C14_RS02410	COG0367	asparagine synthase
D9C14_RS02415	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D9C14_RS02420	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D9C14_RS02430	COG1506	peptidase
D9C14_RS02435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9C14_RS02440	COG1116	anion transmembrane transporter activity
D9C14_RS02445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9C14_RS02450	COG0494	nUDIX hydrolase
D9C14_RS02455	COG4824	toxin secretion phage lysis holin
D9C14_RS02460	COG0783	Belongs to the Dps family
D9C14_RS02475	COG1854	S-ribosylhomocysteine lyase activity
D9C14_RS02480	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D9C14_RS02485	COG0288	reversible hydration of carbon dioxide
D9C14_RS02490	COG0254	rRNA binding
D9C14_RS02495	COG1271	oxidase subunit
D9C14_RS02500	COG1294	oxidase, subunit
D9C14_RS02510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C14_RS02515	COG1321	iron dependent repressor
D9C14_RS02515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C14_RS02520	COG1121	(ABC) transporter
D9C14_RS02525	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9C14_RS02530	COG4948	Mandelate Racemase Muconate Lactonizing
D9C14_RS02535	COG0318	PFAM AMP-dependent synthetase and ligase
D9C14_RS02540	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D9C14_RS02545	COG0596	Alpha beta hydrolase
D9C14_RS02550	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D9C14_RS02555	COG1169	isochorismate synthase
D9C14_RS02565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C14_RS02570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C14_RS02575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C14_RS02580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C14_RS02585	COG0438	transferase activity, transferring glycosyl groups
D9C14_RS02595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C14_RS02600	COG0438	transferase activity, transferring glycosyl groups
D9C14_RS02605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C14_RS02610	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D9C14_RS02615	COG0058	SHG alpha-glucan phosphorylase activity
D9C14_RS02620	COG0297	glycogen (starch) synthase activity
D9C14_RS02625	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9C14_RS02630	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9C14_RS02635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D9C14_RS02760	COG3859	Proton-coupled thiamine transporter YuaJ
D9C14_RS02765	COG1247	-acetyltransferase
D9C14_RS02770	COG2268	Band 7 protein
D9C14_RS02775	COG1585	Membrane protein implicated in regulation of membrane protease activity
D9C14_RS02780	COG2318	DinB family
D9C14_RS02790	COG1454	alcohol dehydrogenase
D9C14_RS02795	COG1012	belongs to the aldehyde dehydrogenase family
D9C14_RS02800	COG1510	regulation of RNA biosynthetic process
D9C14_RS02810	COG0569	domain protein
D9C14_RS02815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9C14_RS02820	COG4682	membrane
D9C14_RS02825	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9C14_RS02830	COG0477	Major facilitator Superfamily
D9C14_RS02835	COG5553	Cysteine dioxygenase type I
D9C14_RS02845	COG1968	undecaprenyl-diphosphatase activity
D9C14_RS02850	COG0628	permease
D9C14_RS02855	COG0673	inositol 2-dehydrogenase activity
D9C14_RS02860	COG4806	L-rhamnose isomerase
D9C14_RS02865	COG3254	rhamnose metabolic process
D9C14_RS02870	COG1070	Carbohydrate kinase
D9C14_RS02875	COG1349	DNA-binding transcription factor activity
D9C14_RS02880	COG3347	Dehydrogenase
D9C14_RS02880	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS02890	COG0840	transmembrane signaling receptor activity
D9C14_RS02895	COG0840	transmembrane signaling receptor activity
D9C14_RS02900	COG0840	transmembrane signaling receptor activity
D9C14_RS02905	COG0840	transmembrane signaling receptor activity
D9C14_RS02920	COG0432	Pfam Uncharacterised protein family UPF0047
D9C14_RS02930	COG0366	Alpha amylase catalytic
D9C14_RS02935	COG1253	flavin adenine dinucleotide binding
D9C14_RS02940	COG2738	Putative neutral zinc metallopeptidase
D9C14_RS02955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9C14_RS02970	COG0166	Belongs to the GPI family
D9C14_RS02975	COG1979	alcohol dehydrogenase
D9C14_RS02980	COG1979	alcohol dehydrogenase
D9C14_RS02985	COG2155	Conserved Protein
D9C14_RS02990	COG1098	S1 RNA binding domain
D9C14_RS02995	COG0436	Aminotransferase
D9C14_RS03000	COG1522	sequence-specific DNA binding
D9C14_RS03015	COG1522	sequence-specific DNA binding
D9C14_RS03020	COG2267	carboxylic ester hydrolase activity
D9C14_RS03030	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D9C14_RS03035	COG2205	protein histidine kinase activity
D9C14_RS03045	COG5018	Exonuclease
D9C14_RS03055	COG2814	Major facilitator Superfamily
D9C14_RS03060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C14_RS03065	COG3011	Protein conserved in bacteria
D9C14_RS03075	COG3290	protein histidine kinase activity
D9C14_RS03080	COG4565	transcriptional regulatory protein
D9C14_RS03085	COG1744	ABC transporter substrate-binding protein PnrA-like
D9C14_RS03090	COG3845	ABC transporter
D9C14_RS03095	COG4603	Belongs to the binding-protein-dependent transport system permease family
D9C14_RS03100	COG1079	Belongs to the binding-protein-dependent transport system permease family
D9C14_RS03105	COG3493	citrate carrier protein
D9C14_RS03115	COG2111	Na H antiporter
D9C14_RS03115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9C14_RS03120	COG2111	Na H antiporter
D9C14_RS03125	COG1006	Multisubunit Na H antiporter MnhC subunit
D9C14_RS03130	COG0651	ATP synthesis coupled electron transport
D9C14_RS03135	COG1863	multisubunit Na H antiporter MnhE subunit
D9C14_RS03140	COG2212	antiporter activity
D9C14_RS03145	COG1320	monovalent cation:proton antiporter activity
D9C14_RS03150	COG2050	protein possibly involved in aromatic compounds catabolism
D9C14_RS03155	COG2197	response regulator
D9C14_RS03160	COG4585	Histidine kinase
D9C14_RS03170	COG0142	geranyltranstransferase activity
D9C14_RS03190	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D9C14_RS03195	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D9C14_RS03200	COG1335	isochorismatase
D9C14_RS03205	COG5506	Protein of unknown function (DUF1694)
D9C14_RS03220	COG0628	permease
D9C14_RS03235	COG1418	mRNA catabolic process
D9C14_RS03240	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS03250	COG1511	domain protein
D9C14_RS03255	COG0433	COG0433 Predicted ATPase
D9C14_RS03255	COG1674	ftsk spoiiie
D9C14_RS03260	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9C14_RS03265	COG5417	Belongs to the EsaB family
D9C14_RS03270	COG4842	Belongs to the WXG100 family
D9C14_RS03275	COG2508	Transcriptional regulator
D9C14_RS03275	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9C14_RS03280	COG0686	Belongs to the AlaDH PNT family
D9C14_RS03285	COG5634	Uncharacterized conserved protein (DUF2278)
D9C14_RS03290	COG3251	PFAM MbtH domain protein
D9C14_RS03295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C14_RS03300	COG3433	isochorismatase activity
D9C14_RS03300	COG1535	isochorismatase
D9C14_RS03305	COG1021	2,3-dihydroxybenzoate-AMP ligase
D9C14_RS03310	COG1169	isochorismate synthase
D9C14_RS03315	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS03320	COG2819	hydrolase of the alpha beta superfamily
D9C14_RS03325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9C14_RS03330	COG1268	BioY protein
D9C14_RS03335	COG2056	Na+-H+ antiporter family
D9C14_RS03340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D9C14_RS03345	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D9C14_RS03350	COG3584	3D domain protein
D9C14_RS03365	COG1252	NADH dehydrogenase
D9C14_RS03370	COG0492	ferredoxin-NADP+ reductase activity
D9C14_RS03380	COG0516	GMP reductase activity
D9C14_RS03385	COG2808	Putative FMN-binding domain
D9C14_RS03390	COG0456	acetyltransferase
D9C14_RS03395	COG0316	Belongs to the HesB IscA family
D9C14_RS03400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D9C14_RS03405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C14_RS03410	COG4844	belongs to the
D9C14_RS03415	COG1252	NADH dehydrogenase
D9C14_RS03420	COG4837	Protein of unknown function (DUF1462)
D9C14_RS03425	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D9C14_RS03430	COG4946	Tricorn protease homolog
D9C14_RS03430	COG0823	Involved in the tonB-independent uptake of proteins
D9C14_RS03430	COG1506	peptidase
D9C14_RS03435	COG0083	homoserine kinase activity
D9C14_RS03440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9C14_RS03445	COG0460	homoserine dehydrogenase
D9C14_RS03450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C14_RS03455	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9C14_RS03460	COG0647	UMP catabolic process
D9C14_RS03465	COG2445	Protein of unknown function DUF86
D9C14_RS03470	COG4470	Protein conserved in bacteria
D9C14_RS03480	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D9C14_RS03485	COG0739	heme binding
D9C14_RS03495	COG3377	Domain of unknown function (DUF1805)
D9C14_RS03500	COG0737	Belongs to the 5'-nucleotidase family
D9C14_RS03505	COG0730	response to heat
D9C14_RS03510	COG1801	Protein of unknown function DUF72
D9C14_RS03520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9C14_RS03525	COG2508	Transcriptional regulator
D9C14_RS03530	COG2233	PERMEase
D9C14_RS03535	COG2233	PERMEase
D9C14_RS03540	COG3648	Uricase
D9C14_RS03540	COG3195	allantoin biosynthetic process
D9C14_RS03545	COG2351	hydroxyisourate hydrolase activity
D9C14_RS03555	COG2080	2 iron, 2 sulfur cluster binding
D9C14_RS03560	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D9C14_RS03565	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D9C14_RS03570	COG2068	MobA-Related Protein
D9C14_RS03575	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D9C14_RS03580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D9C14_RS03585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C14_RS03595	COG2356	endonuclease I
D9C14_RS03600	COG3842	ATPase activity
D9C14_RS03605	COG2188	Transcriptional regulator
D9C14_RS03610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C14_RS03615	COG0395	ABC-type sugar transport system, permease component
D9C14_RS03620	COG1175	transmembrane transport
D9C14_RS03625	COG1653	transport
D9C14_RS03630	COG2222	sugar isomerase
D9C14_RS03635	COG0322	excinuclease ABC activity
D9C14_RS03640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C14_RS03655	COG0346	lactoylglutathione lyase activity
D9C14_RS03660	COG0640	Transcriptional regulator
D9C14_RS03665	COG0719	Fe-S assembly protein
D9C14_RS03670	COG0822	iron-sulfur transferase activity
D9C14_RS03675	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9C14_RS03680	COG0719	Fe-S assembly protein
D9C14_RS03685	COG0396	ATPase activity
D9C14_RS03700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9C14_RS03705	COG1464	Belongs to the NlpA lipoprotein family
D9C14_RS03710	COG2011	ABC-type metal ion transport system permease component
D9C14_RS03715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9C14_RS03725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C14_RS03730	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9C14_RS03740	COG0509	glycine decarboxylation via glycine cleavage system
D9C14_RS03745	COG1393	Belongs to the ArsC family
D9C14_RS03750	COG1960	acyl-CoA dehydrogenase activity
D9C14_RS03755	COG0183	Belongs to the thiolase family
D9C14_RS03760	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9C14_RS03760	COG1024	Enoyl-CoA hydratase
D9C14_RS03770	COG0506	proline dehydrogenase activity
D9C14_RS03780	COG5577	PFAM Coat F domain
D9C14_RS03785	COG1846	Transcriptional regulator
D9C14_RS03790	COG0477	Major facilitator Superfamily
D9C14_RS03795	COG1942	4-Oxalocrotonate Tautomerase
D9C14_RS03800	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS03805	COG0583	DNA-binding transcription factor activity
D9C14_RS03815	COG1120	ATPase activity
D9C14_RS03830	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS03835	COG0783	Belongs to the Dps family
D9C14_RS03840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C14_RS03845	COG0745	RESPONSE REGULATOR receiver
D9C14_RS03850	COG2770	Histidine kinase
D9C14_RS03850	COG2205	protein histidine kinase activity
D9C14_RS03860	COG1309	transcriptional regulator
D9C14_RS03865	COG0114	fumarate hydratase activity
D9C14_RS03875	COG0697	spore germination
D9C14_RS03880	COG0814	amino acid
D9C14_RS03890	COG2197	response regulator
D9C14_RS03895	COG4585	Histidine kinase
D9C14_RS03900	COG4758	membrane
D9C14_RS03905	COG3595	metallopeptidase activity
D9C14_RS03910	COG1842	Phage shock protein A
D9C14_RS03915	COG4758	membrane
D9C14_RS03920	COG2814	Major facilitator Superfamily
D9C14_RS03925	COG2096	Adenosyltransferase
D9C14_RS03930	COG1120	ATPase activity
D9C14_RS03935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C14_RS03940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C14_RS03945	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS03950	COG3386	PFAM SMP-30 Gluconolaconase
D9C14_RS03955	COG2205	protein histidine kinase activity
D9C14_RS03960	COG0745	RESPONSE REGULATOR receiver
D9C14_RS03970	COG1191	sigma factor activity
D9C14_RS03980	COG2140	Oxalate decarboxylase
D9C14_RS03990	COG0577	efflux transmembrane transporter activity
D9C14_RS03995	COG1136	(ABC) transporter
D9C14_RS04000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9C14_RS04005	COG1120	ATPase activity
D9C14_RS04010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C14_RS04015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C14_RS04020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C14_RS04030	COG0531	amino acid
D9C14_RS04045	COG1988	membrane-bound metal-dependent
D9C14_RS04050	COG1368	sulfuric ester hydrolase activity
D9C14_RS04055	COG1910	domain protein
D9C14_RS04060	COG0725	ABC transporter, periplasmic molybdate-binding protein
D9C14_RS04065	COG4149	molybdate abc transporter
D9C14_RS04070	COG0656	L-ascorbic acid biosynthetic process
D9C14_RS04080	COG0025	NhaP-type Na H and K H
D9C14_RS04085	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C14_RS04090	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C14_RS04095	COG3973	AAA domain
D9C14_RS04105	COG2860	membrane
D9C14_RS04110	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D9C14_RS04115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D9C14_RS04120	COG2217	Heavy metal translocating P-type atpase
D9C14_RS04125	COG2217	Heavy metal translocating P-type atpase
D9C14_RS04130	COG2608	mercury ion transmembrane transporter activity
D9C14_RS04135	COG1937	Protein conserved in bacteria
D9C14_RS04140	COG0673	inositol 2-dehydrogenase activity
D9C14_RS04145	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9C14_RS04150	COG1289	transmembrane transporter activity
D9C14_RS04160	COG2076	Multidrug Resistance protein
D9C14_RS04165	COG1309	transcriptional regulator
D9C14_RS04170	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS04180	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D9C14_RS04185	COG0557	exoribonuclease II activity
D9C14_RS04190	COG1647	Serine aminopeptidase, S33
D9C14_RS04195	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9C14_RS04200	COG0596	Alpha beta hydrolase
D9C14_RS04205	COG1476	TRANSCRIPTIONal
D9C14_RS04210	COG1396	sequence-specific DNA binding
D9C14_RS04215	COG1396	sequence-specific DNA binding
D9C14_RS04220	COG1733	regulation of RNA biosynthetic process
D9C14_RS04225	COG0840	transmembrane signaling receptor activity
D9C14_RS04230	COG1174	glycine betaine transport
D9C14_RS04235	COG1732	Glycine betaine
D9C14_RS04240	COG1174	glycine betaine transport
D9C14_RS04245	COG0517	IMP dehydrogenase activity
D9C14_RS04245	COG1125	glycine betaine transport
D9C14_RS04250	COG1510	regulation of RNA biosynthetic process
D9C14_RS04255	COG1174	glycine betaine transport
D9C14_RS04260	COG1732	Glycine betaine
D9C14_RS04265	COG1174	glycine betaine transport
D9C14_RS04270	COG1125	glycine betaine transport
D9C14_RS04270	COG0517	IMP dehydrogenase activity
D9C14_RS04275	COG1510	regulation of RNA biosynthetic process
D9C14_RS04280	COG2095	MarC family integral membrane protein
D9C14_RS04290	COG3064	Membrane
D9C14_RS04295	COG4640	response to antibiotic
D9C14_RS04300	COG0456	acetyltransferase
D9C14_RS04305	COG0148	phosphopyruvate hydratase activity
D9C14_RS04310	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D9C14_RS04315	COG0149	triose-phosphate isomerase activity
D9C14_RS04320	COG0126	phosphoglycerate kinase activity
D9C14_RS04325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9C14_RS04330	COG2390	Transcriptional regulator
D9C14_RS04335	COG2814	Major facilitator Superfamily
D9C14_RS04340	COG1609	Transcriptional regulator
D9C14_RS04345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C14_RS04355	COG0583	DNA-binding transcription factor activity
D9C14_RS04360	COG0697	spore germination
D9C14_RS04365	COG1113	amino acid transport
D9C14_RS04370	COG3858	chitin binding
D9C14_RS04375	COG1556	Lactate utilization protein
D9C14_RS04380	COG1139	Iron-sulfur cluster binding protein
D9C14_RS04385	COG0247	lactate metabolic process
D9C14_RS04390	COG2197	response regulator
D9C14_RS04395	COG4585	Histidine kinase
D9C14_RS04400	COG0842	Transport permease protein
D9C14_RS04405	COG1131	(ABC) transporter
D9C14_RS04410	COG0596	Alpha beta hydrolase
D9C14_RS04415	COG2208	phosphoserine phosphatase activity
D9C14_RS04420	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D9C14_RS04425	COG1874	Beta-galactosidase
D9C14_RS04430	COG3833	ABC-type maltose transport systems, permease component
D9C14_RS04435	COG1175	transmembrane transport
D9C14_RS04440	COG2182	Extracellular solute-binding protein
D9C14_RS04445	COG1609	Transcriptional regulator
D9C14_RS04450	COG2186	Transcriptional regulator
D9C14_RS04455	COG1620	l-lactate permease
D9C14_RS04460	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D9C14_RS04470	COG5039	Polysaccharide pyruvyl transferase
D9C14_RS04475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C14_RS04480	COG0110	maltose O-acetyltransferase activity
D9C14_RS04485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D9C14_RS04490	COG2244	polysaccharide biosynthetic process
D9C14_RS04495	COG1216	Glycosyl transferase, family 2
D9C14_RS04500	COG5039	Polysaccharide pyruvyl transferase
D9C14_RS04505	COG1216	Glycosyl transferase, family 2
D9C14_RS04515	COG0438	transferase activity, transferring glycosyl groups
D9C14_RS04520	COG1215	transferase activity, transferring glycosyl groups
D9C14_RS04525	COG0438	transferase activity, transferring glycosyl groups
D9C14_RS04530	COG1086	Polysaccharide biosynthesis protein
D9C14_RS04535	COG0489	protein tyrosine kinase activity
D9C14_RS04540	COG3944	biosynthesis protein
D9C14_RS04545	COG1396	sequence-specific DNA binding
D9C14_RS04550	COG2272	Belongs to the type-B carboxylesterase lipase family
D9C14_RS04560	COG3479	Phenolic acid decarboxylase
D9C14_RS04570	COG1794	racemase activity, acting on amino acids and derivatives
D9C14_RS04575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C14_RS04580	COG1621	beta-fructofuranosidase activity
D9C14_RS04585	COG1621	beta-fructofuranosidase activity
D9C14_RS04590	COG0531	amino acid
D9C14_RS04595	COG1309	transcriptional regulator
D9C14_RS04600	COG2076	Multidrug Resistance protein
D9C14_RS04605	COG2076	Multidrug Resistance protein
D9C14_RS04615	COG0277	FAD linked oxidase domain protein
D9C14_RS04620	COG3621	Patatin-like phospholipase
D9C14_RS04630	COG0740	serine-type endopeptidase activity
D9C14_RS04635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9C14_RS04640	COG0366	Alpha amylase catalytic
D9C14_RS04645	COG1554	hydrolase, family 65, central catalytic
D9C14_RS04650	COG5521	maltodextrose utilization protein MalA
D9C14_RS04655	COG3833	ABC-type maltose transport systems, permease component
D9C14_RS04660	COG1175	transmembrane transport
D9C14_RS04665	COG2182	Extracellular solute-binding protein
D9C14_RS04670	COG0366	Alpha amylase catalytic
D9C14_RS04675	COG1609	Transcriptional regulator
D9C14_RS04680	COG1611	Belongs to the LOG family
D9C14_RS04685	COG1694	Mazg nucleotide pyrophosphohydrolase
D9C14_RS04690	COG0659	secondary active sulfate transmembrane transporter activity
D9C14_RS04695	COG0288	reversible hydration of carbon dioxide
D9C14_RS04705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9C14_RS04710	COG0577	efflux transmembrane transporter activity
D9C14_RS04715	COG1136	(ABC) transporter
D9C14_RS04720	COG5002	protein histidine kinase activity
D9C14_RS04725	COG0745	RESPONSE REGULATOR receiver
D9C14_RS04735	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D9C14_RS04740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C14_RS04745	COG1481	regulation of sporulation
D9C14_RS04750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D9C14_RS04755	COG1660	Displays ATPase and GTPase activities
D9C14_RS04760	COG1051	belongs to the nudix hydrolase family
D9C14_RS04765	COG0492	ferredoxin-NADP+ reductase activity
D9C14_RS04770	COG0791	NLP P60 protein
D9C14_RS04770	COG3883	PFAM NLP P60 protein
D9C14_RS04775	COG0457	Tetratricopeptide repeat
D9C14_RS04780	COG1132	(ABC) transporter
D9C14_RS04800	COG0140	phosphoribosyl-ATP diphosphatase activity
D9C14_RS04800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D9C14_RS04805	COG0107	imidazoleglycerol-phosphate synthase activity
D9C14_RS04810	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D9C14_RS04815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D9C14_RS04820	COG0131	Imidazoleglycerol-phosphate dehydratase
D9C14_RS04825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D9C14_RS04830	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D9C14_RS04835	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D9C14_RS04840	COG4990	cell redox homeostasis
D9C14_RS04845	COG5297	Belongs to the glycosyl hydrolase family 6
D9C14_RS04850	COG0110	maltose O-acetyltransferase activity
D9C14_RS04855	COG0546	phosphoglycolate phosphatase activity
D9C14_RS04860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D9C14_RS04865	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D9C14_RS04870	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D9C14_RS04875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D9C14_RS04880	COG0363	glucosamine-6-phosphate deaminase activity
D9C14_RS04885	COG2188	Transcriptional regulator
D9C14_RS04890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D9C14_RS04895	COG1846	Transcriptional regulator
D9C14_RS04910	COG1846	Transcriptional regulator
D9C14_RS04915	COG2814	Major facilitator Superfamily
D9C14_RS04920	COG1950	PFAM Membrane protein of
D9C14_RS04925	COG1983	PspC domain protein
D9C14_RS04930	COG3595	metallopeptidase activity
D9C14_RS04945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C14_RS04950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D9C14_RS04955	COG0556	nucleotide-excision repair
D9C14_RS04960	COG4897	Protein conserved in bacteria
D9C14_RS04965	COG3848	Pyruvate phosphate dikinase
D9C14_RS04965	COG0574	Belongs to the PEP-utilizing enzyme family
D9C14_RS04970	COG1309	transcriptional regulator
D9C14_RS04975	COG2814	Major facilitator Superfamily
D9C14_RS04980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C14_RS04990	COG3409	Peptidoglycan-binding domain 1 protein
D9C14_RS04990	COG0793	Belongs to the peptidase S41A family
D9C14_RS04995	COG2177	Part of the ABC transporter FtsEX involved in
D9C14_RS05000	COG2884	Cell division ATP-binding protein ftsE
D9C14_RS05005	COG2010	Cytochrome c
D9C14_RS05010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C14_RS05020	COG0653	protein targeting
D9C14_RS05025	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D9C14_RS05040	COG1516	flagellar protein fliS
D9C14_RS05045	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D9C14_RS05050	COG1334	flagellar protein FlaG
D9C14_RS05055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C14_RS05060	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D9C14_RS05065	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D9C14_RS05075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C14_RS05080	COG4786	Flagellar basal body rod
D9C14_RS05080	COG1256	bacterial-type flagellum assembly
D9C14_RS05085	COG3418	PFAM FlgN family protein
D9C14_RS05090	COG2747	anti-sigma28 factor FlgM
D9C14_RS05100	COG1040	competence protein
D9C14_RS05110	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D9C14_RS05115	COG1307	EDD domain protein, DegV family
D9C14_RS05120	COG2197	response regulator
D9C14_RS05125	COG4585	Histidine kinase
D9C14_RS05130	COG1739	Uncharacterized protein family UPF0029
D9C14_RS05135	COG1316	TRANSCRIPTIONal
D9C14_RS05140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9C14_RS05145	COG0438	transferase activity, transferring glycosyl groups
D9C14_RS05150	COG1215	transferase activity, transferring glycosyl groups
D9C14_RS05155	COG3206	protein involved in exopolysaccharide biosynthesis
D9C14_RS05160	COG3307	-O-antigen
D9C14_RS05165	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C14_RS05170	COG0438	transferase activity, transferring glycosyl groups
D9C14_RS05170	COG0297	glycogen (starch) synthase activity
D9C14_RS05175	COG2244	polysaccharide biosynthetic process
D9C14_RS05190	COG2247	cell wall binding repeat
D9C14_RS05190	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C14_RS05195	COG2385	sporulation resulting in formation of a cellular spore
D9C14_RS05195	COG2247	cell wall binding repeat
D9C14_RS05205	COG1316	TRANSCRIPTIONal
D9C14_RS05210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D9C14_RS05230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C14_RS05235	COG1134	teichoic acid transport
D9C14_RS05240	COG1682	transport, permease protein
D9C14_RS05255	COG1215	transferase activity, transferring glycosyl groups
D9C14_RS05255	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C14_RS05260	COG0463	Glycosyl transferase, family 2
D9C14_RS05305	COG4193	domain, Protein
D9C14_RS05310	COG1482	cell wall glycoprotein biosynthetic process
D9C14_RS05315	COG0697	spore germination
D9C14_RS05320	COG0814	amino acid
D9C14_RS05330	COG2814	Major facilitator Superfamily
D9C14_RS05335	COG1316	TRANSCRIPTIONal
D9C14_RS05340	COG0561	phosphatase activity
D9C14_RS05345	COG0791	NLP P60 protein
D9C14_RS05355	COG2843	Capsule synthesis protein
D9C14_RS05365	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9C14_RS05370	COG1609	Transcriptional regulator
D9C14_RS05375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C14_RS05380	COG1869	D-ribose catabolic process
D9C14_RS05385	COG1129	ABC transporter
D9C14_RS05390	COG1172	Belongs to the binding-protein-dependent transport system permease family
D9C14_RS05395	COG1879	ABC-type sugar transport system periplasmic component
D9C14_RS05400	COG3103	Sh3 type 3 domain protein
D9C14_RS05410	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9C14_RS05415	COG3527	Alpha-acetolactate decarboxylase
D9C14_RS05420	COG0028	Belongs to the TPP enzyme family
D9C14_RS05425	COG0583	DNA-binding transcription factor activity
D9C14_RS05430	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9C14_RS05445	COG5337	Spore coat protein CotH
D9C14_RS05455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9C14_RS05465	COG0405	Gamma-glutamyltransferase
D9C14_RS05470	COG1522	sequence-specific DNA binding
D9C14_RS05475	COG2059	Chromate
D9C14_RS05480	COG2059	Chromate
D9C14_RS05490	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9C14_RS05495	COG0583	DNA-binding transcription factor activity
D9C14_RS05525	COG5444	nuclease activity
D9C14_RS05545	COG3878	Protein conserved in bacteria
D9C14_RS05550	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C14_RS05555	COG4464	protein tyrosine phosphatase activity
D9C14_RS05560	COG0489	protein tyrosine kinase activity
D9C14_RS05565	COG3944	biosynthesis protein
D9C14_RS05575	COG4715	Zinc finger, swim domain protein
D9C14_RS05580	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9C14_RS05585	COG0561	phosphatase activity
D9C14_RS05590	COG1349	DNA-binding transcription factor activity
D9C14_RS05595	COG0629	single-stranded DNA binding
D9C14_RS05610	COG3764	Sortase (surface protein transpeptidase)
D9C14_RS05615	COG0745	RESPONSE REGULATOR receiver
D9C14_RS05615	COG2972	Histidine kinase
D9C14_RS05620	COG1970	mechanosensitive ion channel activity
D9C14_RS05625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9C14_RS05630	COG0457	Tetratricopeptide repeat
D9C14_RS05635	COG4786	Flagellar basal body rod
D9C14_RS05640	COG4786	Flagellar basal body rod
D9C14_RS05645	COG1077	Cell shape determining protein MreB Mrl
D9C14_RS05650	COG1609	Transcriptional regulator
D9C14_RS05660	COG1846	Transcriptional regulator
D9C14_RS05665	COG2814	Major facilitator Superfamily
D9C14_RS05670	COG3420	alginic acid biosynthetic process
D9C14_RS05675	COG1953	Uracil, thiamine, allantoin
D9C14_RS05680	COG0477	Major facilitator Superfamily
D9C14_RS05685	COG1335	isochorismatase
D9C14_RS05695	COG0004	ammonium transporteR
D9C14_RS05700	COG0347	Belongs to the P(II) protein family
D9C14_RS05705	COG0671	phosphoesterase, PA-phosphatase related
D9C14_RS05715	COG0739	heme binding
D9C14_RS05720	COG1247	-acetyltransferase
D9C14_RS05740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C14_RS05745	COG0789	Transcriptional regulator
D9C14_RS05755	COG2910	NAD(P)H-binding
D9C14_RS05760	COG1959	2 iron, 2 sulfur cluster binding
D9C14_RS05765	COG0804	urea catabolic process
D9C14_RS05770	COG0832	Belongs to the urease beta subunit family
D9C14_RS05775	COG0831	urea catabolic process
D9C14_RS05790	COG3237	CsbD-like
D9C14_RS05795	COG1994	Peptidase M50
D9C14_RS05800	COG0457	Tetratricopeptide repeat
D9C14_RS05810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D9C14_RS05815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D9C14_RS05825	COG2304	oxidoreductase activity
D9C14_RS05835	COG2304	oxidoreductase activity
D9C14_RS05840	COG2385	sporulation resulting in formation of a cellular spore
D9C14_RS05845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9C14_RS05855	COG4836	Membrane
D9C14_RS05865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D9C14_RS05870	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D9C14_RS05875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D9C14_RS05880	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D9C14_RS05885	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9C14_RS05890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D9C14_RS05900	COG0356	it plays a direct role in the translocation of protons across the membrane
D9C14_RS05910	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D9C14_RS05915	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D9C14_RS05920	COG4475	Protein of unknown function (DUF436)
D9C14_RS05925	COG0698	ribose 5-phosphate isomerase
D9C14_RS05930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C14_RS05935	COG1971	Probably functions as a manganese efflux pump
D9C14_RS05940	COG0009	L-threonylcarbamoyladenylate synthase
D9C14_RS05945	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D9C14_RS05965	COG2890	protein-(glutamine-N5) methyltransferase activity
D9C14_RS05970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D9C14_RS05975	COG0346	lactoylglutathione lyase activity
D9C14_RS05980	COG0789	Transcriptional regulator
D9C14_RS05985	COG0679	Auxin Efflux Carrier
D9C14_RS05990	COG0281	malic enzyme
D9C14_RS05995	COG1435	thymidine kinase activity
D9C14_RS06005	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D9C14_RS06015	COG1494	fructose-1,6-bisphosphatase
D9C14_RS06020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9C14_RS06025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D9C14_RS06030	COG0191	fructose-bisphosphate aldolase activity
D9C14_RS06035	COG2204	response regulator
D9C14_RS06040	COG4821	SIS domain
D9C14_RS06045	COG0504	CTP synthase activity
D9C14_RS06050	COG3343	RNA polymerase activity
D9C14_RS06055	COG1960	acyl-CoA dehydrogenase activity
D9C14_RS06060	COG2181	nitrate reductase activity
D9C14_RS06060	COG0247	lactate metabolic process
D9C14_RS06065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C14_RS06070	COG4294	response to UV
D9C14_RS06080	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C14_RS06085	COG1132	(ABC) transporter
D9C14_RS06090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C14_RS06100	COG2181	nitrate reductase activity
D9C14_RS06105	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D9C14_RS06110	COG1140	nitrate reductase beta subunit
D9C14_RS06115	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D9C14_RS06120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9C14_RS06130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9C14_RS06135	COG2223	nitrite transmembrane transporter activity
D9C14_RS06140	COG0018	arginyl-trna synthetase
D9C14_RS06145	COG4506	Protein conserved in bacteria
D9C14_RS06160	COG0535	radical SAM domain protein
D9C14_RS06170	COG1131	(ABC) transporter
D9C14_RS06175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9C14_RS06180	COG0612	Peptidase, M16
D9C14_RS06185	COG0612	Peptidase, M16
D9C14_RS06195	COG3391	amine dehydrogenase activity
D9C14_RS06200	COG3391	amine dehydrogenase activity
D9C14_RS06210	COG0457	Tetratricopeptide repeat
D9C14_RS06240	COG1131	(ABC) transporter
D9C14_RS06250	COG0010	Belongs to the arginase family
D9C14_RS06255	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9C14_RS06260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C14_RS06275	COG1994	Peptidase M50
D9C14_RS06280	COG1942	4-Oxalocrotonate Tautomerase
D9C14_RS06285	COG1846	Transcriptional regulator
D9C14_RS06290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9C14_RS06300	COG0477	Major facilitator Superfamily
D9C14_RS06305	COG1959	2 iron, 2 sulfur cluster binding
D9C14_RS06310	COG3465	dGTPase activity
D9C14_RS06315	COG1078	dGTPase activity
D9C14_RS06320	COG4844	belongs to the
D9C14_RS06330	COG0697	spore germination
D9C14_RS06335	COG0095	Lipoate-protein ligase
D9C14_RS06340	COG0583	DNA-binding transcription factor activity
D9C14_RS06345	COG0280	phosphate acetyltransferase
D9C14_RS06350	COG3253	May function as heme-dependent peroxidase
D9C14_RS06355	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS06360	COG0436	Aminotransferase
D9C14_RS06365	COG2814	Major facilitator Superfamily
D9C14_RS06370	COG0151	Belongs to the GarS family
D9C14_RS06375	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS06380	COG1917	Cupin 2, conserved barrel domain protein
D9C14_RS06385	COG0077	Prephenate dehydratase
D9C14_RS06390	COG2814	Major facilitator Superfamily
D9C14_RS06395	COG0833	amino acid
D9C14_RS06400	COG4187	Peptidase family M20/M25/M40
D9C14_RS06405	COG1012	belongs to the aldehyde dehydrogenase family
D9C14_RS06410	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C14_RS06420	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D9C14_RS06425	COG1091	dTDP-4-dehydrorhamnose reductase activity
D9C14_RS06430	COG1088	dTDP-glucose 4,6-dehydratase activity
D9C14_RS06435	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D9C14_RS06440	COG3980	spore coat polysaccharide biosynthesis protein
D9C14_RS06445	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D9C14_RS06450	COG2089	acid synthase
D9C14_RS06455	COG0456	acetyltransferase
D9C14_RS06460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C14_RS06465	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C14_RS06470	COG0463	Glycosyl transferase, family 2
D9C14_RS06485	COG2363	Small membrane protein
D9C14_RS06490	COG2233	PERMEase
D9C14_RS06500	COG1012	belongs to the aldehyde dehydrogenase family
D9C14_RS06505	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D9C14_RS06510	COG1216	Glycosyl transferase, family 2
D9C14_RS06515	COG0351	phosphomethylpyrimidine kinase
D9C14_RS06525	COG1621	beta-fructofuranosidase activity
D9C14_RS06530	COG1263	PTS System
D9C14_RS06530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C14_RS06535	COG2116	formate transmembrane transporter activity
D9C14_RS06540	COG3711	transcriptional antiterminator
D9C14_RS06550	COG1404	Belongs to the peptidase S8 family
D9C14_RS06555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C14_RS06560	COG0778	Nitroreductase
D9C14_RS06565	COG0772	Belongs to the SEDS family
D9C14_RS06575	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9C14_RS06580	COG1845	cytochrome c oxidase, subunit III
D9C14_RS06585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9C14_RS06590	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9C14_RS06595	COG2261	transglycosylase associated protein
D9C14_RS06600	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D9C14_RS06605	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D9C14_RS06610	COG2246	polysaccharide biosynthetic process
D9C14_RS06615	COG1309	transcriptional regulator
D9C14_RS06625	COG3162	membrane
D9C14_RS06630	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C14_RS06635	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9C14_RS06640	COG2837	iron assimilation
D9C14_RS06645	COG2822	iron ion transport
D9C14_RS06650	COG0672	)-iron permease
D9C14_RS06655	COG0352	thiamine-phosphate diphosphorylase activity
D9C14_RS06660	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D9C14_RS06665	COG0583	DNA-binding transcription factor activity
D9C14_RS06670	COG1380	Effector of murein hydrolase LrgA
D9C14_RS06675	COG1346	cytolysis
D9C14_RS06680	COG2814	Major facilitator Superfamily
D9C14_RS06685	COG4895	conserved protein (DUF2196)
D9C14_RS06690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D9C14_RS06695	COG0346	lactoylglutathione lyase activity
D9C14_RS06700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C14_RS06705	COG1404	Belongs to the peptidase S8 family
D9C14_RS06710	COG1263	PTS System
D9C14_RS06710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C14_RS06715	COG3711	transcriptional antiterminator
D9C14_RS06720	COG1442	glycosyl transferase family 8
D9C14_RS06725	COG5522	Integral membrane protein (intg_mem_TP0381)
D9C14_RS06730	COG1846	Transcriptional regulator
D9C14_RS06735	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9C14_RS06740	COG2234	aminopeptidase activity
D9C14_RS06755	COG2814	Major facilitator Superfamily
D9C14_RS06760	COG2357	RelA SpoT domain protein
D9C14_RS06765	COG1575	Belongs to the MenA family. Type 1 subfamily
D9C14_RS06785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C14_RS06790	COG1696	Membrane protein involved in D-alanine export
D9C14_RS06795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C14_RS06800	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D9C14_RS06805	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D9C14_RS06810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C14_RS06815	COG1486	melibiose metabolic process
D9C14_RS06820	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9C14_RS06825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C14_RS06830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C14_RS06835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C14_RS06835	COG3711	transcriptional antiterminator
D9C14_RS06845	COG2094	Belongs to the DNA glycosylase MPG family
D9C14_RS06850	COG0753	catalase activity
D9C14_RS06860	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C14_RS06865	COG1131	(ABC) transporter
D9C14_RS06885	COG1595	DNA-templated transcription, initiation
D9C14_RS06890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9C14_RS06895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D9C14_RS06900	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D9C14_RS06905	COG4988	ABC transporter
D9C14_RS06910	COG1294	oxidase, subunit
D9C14_RS06915	COG1271	oxidase subunit
D9C14_RS06920	COG3493	citrate carrier protein
D9C14_RS06925	COG0501	Belongs to the peptidase M48B family
D9C14_RS06935	COG0726	polysaccharide deacetylase
D9C14_RS06940	COG3842	ATPase activity
D9C14_RS06945	COG2508	Transcriptional regulator
D9C14_RS06950	COG1012	belongs to the aldehyde dehydrogenase family
D9C14_RS06955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C14_RS06970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9C14_RS06975	COG1881	PFAM PEBP family protein
D9C14_RS06980	COG0583	DNA-binding transcription factor activity
D9C14_RS06990	COG4585	Histidine kinase
D9C14_RS06995	COG2197	response regulator
D9C14_RS07000	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9C14_RS07010	COG4894	glucomannan catabolic process
D9C14_RS07015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C14_RS07020	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C14_RS07025	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS07030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9C14_RS07035	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9C14_RS07040	COG2610	gluconate transmembrane transporter activity
D9C14_RS07045	COG0500	methyltransferase
D9C14_RS07050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C14_RS07065	COG0753	catalase activity
D9C14_RS07065	COG0693	protein deglycase activity
D9C14_RS07070	COG2851	Citrate transporter
D9C14_RS07075	COG2273	Hydrolase Family 16
D9C14_RS07080	COG3711	transcriptional antiterminator
D9C14_RS07090	COG2270	Major facilitator Superfamily
D9C14_RS07095	COG0513	Belongs to the DEAD box helicase family
D9C14_RS07100	COG3401	FG-GAP repeat protein
D9C14_RS07100	COG2755	lipolytic protein G-D-S-L family
D9C14_RS07150	COG3209	COG3209 Rhs family protein
D9C14_RS07155	COG0697	spore germination
D9C14_RS07165	COG0789	Transcriptional regulator
D9C14_RS07185	COG0589	response to stress
D9C14_RS07190	COG2723	6-phospho-beta-galactosidase activity
D9C14_RS07195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C14_RS07195	COG1263	PTS System
D9C14_RS07195	COG2190	(PTS) system
D9C14_RS07245	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C14_RS07260	COG2986	histidine ammonia-lyase
D9C14_RS07265	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D9C14_RS07270	COG1228	amidohydrolase
D9C14_RS07275	COG0010	Belongs to the arginase family
D9C14_RS07280	COG0833	amino acid
D9C14_RS07285	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D9C14_RS07290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C14_RS07295	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D9C14_RS07300	COG2390	Transcriptional regulator
D9C14_RS07310	COG3192	ethanolamine utilization protein
D9C14_RS07315	COG2079	MmgE PrpD family protein
D9C14_RS07320	COG1473	amidohydrolase
D9C14_RS07325	COG1126	abc transporter atp-binding protein
D9C14_RS07330	COG0765	amino acid transport
D9C14_RS07335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C14_RS07340	COG0456	acetyltransferase
D9C14_RS07345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C14_RS07355	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D9C14_RS07360	COG0561	phosphatase activity
D9C14_RS07390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C14_RS07395	COG5294	Protein conserved in bacteria
D9C14_RS07400	COG0577	efflux transmembrane transporter activity
D9C14_RS07405	COG1136	(ABC) transporter
D9C14_RS07410	COG2205	protein histidine kinase activity
D9C14_RS07415	COG0745	RESPONSE REGULATOR receiver
D9C14_RS07420	COG0191	fructose-bisphosphate aldolase activity
D9C14_RS07425	COG1082	Xylose isomerase domain protein TIM barrel
D9C14_RS07430	COG1082	Xylose isomerase domain protein TIM barrel
D9C14_RS07435	COG0673	inositol 2-dehydrogenase activity
D9C14_RS07440	COG2814	Major facilitator Superfamily
D9C14_RS07445	COG1082	Xylose isomerase domain protein TIM barrel
D9C14_RS07450	COG3962	Belongs to the TPP enzyme family
D9C14_RS07455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C14_RS07465	COG1012	belongs to the aldehyde dehydrogenase family
D9C14_RS07470	COG1349	DNA-binding transcription factor activity
D9C14_RS07475	COG0667	Aldo Keto reductase
D9C14_RS07490	COG2814	Major facilitator Superfamily
D9C14_RS07495	COG0326	Molecular chaperone. Has ATPase activity
D9C14_RS07505	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS07510	COG1309	transcriptional regulator
D9C14_RS07515	COG1012	belongs to the aldehyde dehydrogenase family
D9C14_RS07525	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D9C14_RS07535	COG1714	RDD family
D9C14_RS07540	COG2311	Membrane
D9C14_RS07545	COG1917	Cupin 2, conserved barrel domain protein
D9C14_RS07550	COG1309	transcriptional regulator
D9C14_RS07555	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS07560	COG1846	Transcriptional regulator
D9C14_RS07565	COG1380	Effector of murein hydrolase LrgA
D9C14_RS07570	COG1346	cytolysis
D9C14_RS07575	COG5039	Polysaccharide pyruvyl transferase
D9C14_RS07580	COG1929	Belongs to the glycerate kinase type-1 family
D9C14_RS07585	COG1802	Transcriptional regulator
D9C14_RS07590	COG1070	Carbohydrate kinase
D9C14_RS07595	COG2610	gluconate transmembrane transporter activity
D9C14_RS07600	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9C14_RS07605	COG0450	alkyl hydroperoxide reductase
D9C14_RS07610	COG3634	alkyl hydroperoxide reductase activity
D9C14_RS07620	COG2723	6-phospho-beta-galactosidase activity
D9C14_RS07625	COG2190	(PTS) system
D9C14_RS07630	COG2190	(PTS) system
D9C14_RS07630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C14_RS07630	COG1263	PTS System
D9C14_RS07635	COG2188	Transcriptional regulator
D9C14_RS07645	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
D9C14_RS07680	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D9C14_RS07695	COG1063	alcohol dehydrogenase
D9C14_RS07715	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D9C14_RS07720	COG0456	acetyltransferase
D9C14_RS07725	COG0457	Tetratricopeptide repeat
D9C14_RS07735	COG0010	Belongs to the arginase family
D9C14_RS07740	COG0833	amino acid
D9C14_RS07745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9C14_RS07750	COG3829	transcription factor binding
D9C14_RS07755	COG5002	protein histidine kinase activity
D9C14_RS07760	COG0745	RESPONSE REGULATOR receiver
D9C14_RS07780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C14_RS07785	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D9C14_RS07790	COG4853	Protein conserved in bacteria
D9C14_RS07795	COG4863	YycH protein
D9C14_RS07800	COG5002	protein histidine kinase activity
D9C14_RS07805	COG0745	RESPONSE REGULATOR receiver
D9C14_RS07835	COG0346	lactoylglutathione lyase activity
D9C14_RS07840	COG0305	Participates in initiation and elongation during chromosome replication
D9C14_RS07855	COG3093	addiction module antidote protein HigA
D9C14_RS07860	COG2807	transmembrane transport
D9C14_RS07865	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9C14_RS07870	COG0359	binds to the 23S rRNA
D9C14_RS07875	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D9C14_RS07880	COG4241	membrane
D9C14_RS07890	COG5577	PFAM Coat F domain
D9C14_RS07895	COG1733	regulation of RNA biosynthetic process
D9C14_RS07900	COG1227	inorganic diphosphatase activity
D9C14_RS07910	COG2271	Major facilitator Superfamily
D9C14_RS07915	COG4978	Transcriptional regulator
D9C14_RS07915	COG0789	Transcriptional regulator
D9C14_RS07925	COG4319	ketosteroid isomerase
D9C14_RS07930	COG1357	PFAM Pentapeptide repeats (8 copies)
D9C14_RS07935	COG2814	Major facilitator Superfamily
D9C14_RS07940	COG0583	DNA-binding transcription factor activity
D9C14_RS07945	COG2153	protein acetylation
D9C14_RS07960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C14_RS07965	COG1846	Transcriptional regulator
D9C14_RS07970	COG2153	protein acetylation
D9C14_RS07975	COG2364	Membrane
D9C14_RS07980	COG0456	acetyltransferase
D9C14_RS07985	COG2315	Protein conserved in bacteria
D9C14_RS07990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C14_RS08000	COG2814	Major facilitator Superfamily
D9C14_RS08010	COG1331	Highly conserved protein containing a thioredoxin domain
D9C14_RS08015	COG1266	CAAX protease self-immunity
D9C14_RS08020	COG0477	Major facilitator Superfamily
D9C14_RS08020	COG2814	Major facilitator Superfamily
D9C14_RS08025	COG0110	maltose O-acetyltransferase activity
D9C14_RS08030	COG0346	lactoylglutathione lyase activity
D9C14_RS08035	COG1609	Transcriptional regulator
D9C14_RS08040	COG0708	Exodeoxyribonuclease III
D9C14_RS08045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D9C14_RS08050	COG0629	single-stranded DNA binding
D9C14_RS08055	COG0360	Binds together with S18 to 16S ribosomal RNA
D9C14_RS08060	COG0012	GTP binding
D9C14_RS08065	COG0243	molybdopterin cofactor binding
D9C14_RS08070	COG4481	Protein conserved in bacteria
D9C14_RS08075	COG3949	Membrane
D9C14_RS08085	COG1475	DNA binding
D9C14_RS08090	COG1192	Involved in chromosome partitioning
D9C14_RS08100	COG1475	DNA binding
D9C14_RS08105	COG0357	Ribosomal RNA small subunit methyltransferase G
D9C14_RS08110	COG0445	tRNA wobble uridine modification
D9C14_RS08115	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D9C14_RS08120	COG1847	R3H domain protein
D9C14_RS08125	COG0706	membrane insertase activity
D9C14_RS08130	COG0594	ribonuclease P activity
D9C14_RS08140	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D9C14_RS08145	COG0592	DNA-directed DNA polymerase activity
D9C14_RS08150	COG2501	S4 domain
D9C14_RS08155	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D9C14_RS08165	COG0187	DNA topoisomerase II activity
D9C14_RS08170	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9C14_RS08205	COG0517	IMP dehydrogenase activity
D9C14_RS08205	COG0516	GMP reductase activity
D9C14_RS08210	COG1686	Belongs to the peptidase S11 family
D9C14_RS08215	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D9C14_RS08220	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D9C14_RS08230	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D9C14_RS08240	COG1428	Deoxynucleoside kinase
D9C14_RS08245	COG1428	Deoxynucleoside kinase
D9C14_RS08250	COG3858	chitin binding
D9C14_RS08250	COG1388	LysM domain
D9C14_RS08255	COG1335	isochorismatase
D9C14_RS08260	COG0590	tRNA wobble adenosine to inosine editing
D9C14_RS08270	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D9C14_RS08275	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D9C14_RS08280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D9C14_RS08325	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D9C14_RS08330	COG3853	Toxic anion resistance protein (TelA)
D9C14_RS08335	COG1982	Orn Lys Arg decarboxylase major
D9C14_RS08340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9C14_RS08345	COG3870	Protein conserved in bacteria
D9C14_RS08350	COG1728	Protein conserved in bacteria
D9C14_RS08355	COG0470	DNA polymerase III
D9C14_RS08360	COG1774	PSP1 C-terminal conserved region
D9C14_RS08365	COG4467	Involved in initiation control of chromosome replication
D9C14_RS08370	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D9C14_RS08375	COG2827	Endonuclease containing a URI domain
D9C14_RS08380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D9C14_RS08385	COG2002	toxin-antitoxin pair type II binding
D9C14_RS08390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C14_RS08390	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C14_RS08395	COG0084	hydrolase, TatD family'
D9C14_RS08400	COG3584	3D domain protein
D9C14_RS08400	COG3583	domain protein
D9C14_RS08405	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9C14_RS08410	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D9C14_RS08420	COG4466	Protein conserved in bacteria
D9C14_RS08430	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D9C14_RS08435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C14_RS08440	COG0251	oxidation-reduction process
D9C14_RS08445	COG2088	sporulation resulting in formation of a cellular spore
D9C14_RS08450	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D9C14_RS08455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D9C14_RS08460	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D9C14_RS08465	COG0193	aminoacyl-tRNA hydrolase activity
D9C14_RS08475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D9C14_RS08480	COG2002	toxin-antitoxin pair type II binding
D9C14_RS08485	COG2244	polysaccharide biosynthetic process
D9C14_RS08490	COG3956	TIGRFAM MazG family protein
D9C14_RS08495	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D9C14_RS08510	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D9C14_RS08515	COG1098	S1 RNA binding domain
D9C14_RS08530	COG2208	phosphoserine phosphatase activity
D9C14_RS08535	COG2304	oxidoreductase activity
D9C14_RS08540	COG0515	serine threonine protein kinase
D9C14_RS08545	COG0037	tRNA processing
D9C14_RS08550	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D9C14_RS08555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9C14_RS08560	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D9C14_RS08565	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D9C14_RS08570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9C14_RS08575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C14_RS08580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9C14_RS08585	COG0512	Glutamine amidotransferase of anthranilate synthase
D9C14_RS08590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C14_RS08595	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D9C14_RS08600	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D9C14_RS08605	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D9C14_RS08610	COG1396	sequence-specific DNA binding
D9C14_RS08615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9C14_RS08620	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D9C14_RS08700	COG4463	regulation of RNA biosynthetic process
D9C14_RS08705	COG3880	PFAM UvrB UvrC protein
D9C14_RS08710	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D9C14_RS08715	COG0542	response to heat
D9C14_RS08720	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D9C14_RS08725	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D9C14_RS08730	COG4956	integral membrane protein (PIN domain superfamily)
D9C14_RS08735	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D9C14_RS08740	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D9C14_RS08745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D9C14_RS08755	COG1045	serine acetyltransferase
D9C14_RS08760	COG0215	cysteine-tRNA ligase activity
D9C14_RS08765	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D9C14_RS08770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9C14_RS08775	COG3688	RNA-binding protein containing a PIN domain
D9C14_RS08780	COG1595	DNA-templated transcription, initiation
D9C14_RS08790	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9C14_RS08795	COG0250	Participates in transcription elongation, termination and antitermination
D9C14_RS08805	COG0081	regulation of translation
D9C14_RS08810	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D9C14_RS08820	COG2813	Specifically methylates the guanine in position
D9C14_RS08825	COG0085	RNA polymerase activity
D9C14_RS08830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D9C14_RS08835	COG1358	cellular component organization or biogenesis
D9C14_RS08840	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D9C14_RS08845	COG0049	tRNA binding
D9C14_RS08850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D9C14_RS08855	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D9C14_RS08860	COG0596	Alpha beta hydrolase
D9C14_RS08870	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D9C14_RS08875	COG0088	Forms part of the polypeptide exit tunnel
D9C14_RS08885	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D9C14_RS08905	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D9C14_RS08915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D9C14_RS08920	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D9C14_RS08930	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D9C14_RS08940	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D9C14_RS08945	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D9C14_RS08950	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D9C14_RS08955	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D9C14_RS08965	COG0200	Binds to the 23S rRNA
D9C14_RS08970	COG0201	protein transport
D9C14_RS08975	COG0563	adenylate kinase activity
D9C14_RS08980	COG0024	Methionine aminopeptidase
D9C14_RS08985	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D9C14_RS08995	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9C14_RS09000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D9C14_RS09005	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D9C14_RS09010	COG0202	RNA polymerase activity
D9C14_RS09015	COG0203	ribosomal protein L17
D9C14_RS09020	COG1122	ATPase activity
D9C14_RS09025	COG1122	ATPase activity
D9C14_RS09030	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9C14_RS09035	COG0101	tRNA pseudouridine synthase activity
D9C14_RS09040	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D9C14_RS09045	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D9C14_RS09050	COG2226	methyltransferase
D9C14_RS09060	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C14_RS09065	COG0489	protein tyrosine kinase activity
D9C14_RS09075	COG2194	sulfuric ester hydrolase activity
D9C14_RS09080	COG0726	polysaccharide deacetylase
D9C14_RS09165	COG0659	secondary active sulfate transmembrane transporter activity
D9C14_RS09170	COG0385	Bile acid
D9C14_RS09175	COG2819	hydrolase of the alpha beta superfamily
D9C14_RS09180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C14_RS09185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C14_RS09190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C14_RS09195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C14_RS09195	COG2207	Transcriptional regulator
D9C14_RS09200	COG3876	Protein conserved in bacteria
D9C14_RS09205	COG1472	Belongs to the glycosyl hydrolase 3 family
D9C14_RS09210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C14_RS09215	COG1263	PTS System
D9C14_RS09215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C14_RS09220	COG1737	Transcriptional regulator
D9C14_RS09225	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D9C14_RS09230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C14_RS09235	COG1683	Conserved Protein
D9C14_RS09265	COG1595	DNA-templated transcription, initiation
D9C14_RS09270	COG5662	AntiSigma factor
D9C14_RS09275	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9C14_RS09280	COG4856	YbbR-like protein
D9C14_RS09285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9C14_RS09290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9C14_RS09300	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9C14_RS09305	COG2169	Transcriptional regulator
D9C14_RS09310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9C14_RS09315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9C14_RS09320	COG3002	Belongs to the UPF0753 family
D9C14_RS09325	COG0288	reversible hydration of carbon dioxide
D9C14_RS09335	COG5609	conserved protein (DUF2294)
D9C14_RS09340	COG0640	Transcriptional regulator
D9C14_RS09345	COG2814	Major facilitator Superfamily
D9C14_RS09360	COG1404	Belongs to the peptidase S8 family
D9C14_RS09380	COG1132	(ABC) transporter
D9C14_RS09385	COG0596	Alpha beta hydrolase
D9C14_RS09390	COG0745	RESPONSE REGULATOR receiver
D9C14_RS09395	COG0642	Histidine kinase
D9C14_RS09405	COG0515	serine threonine protein kinase
D9C14_RS09420	COG1113	amino acid transport
D9C14_RS09435	COG2602	Beta-lactamase
D9C14_RS09440	COG2124	cytochrome p450
D9C14_RS09450	COG0531	amino acid
D9C14_RS09455	COG0584	glycerophosphoryl diester phosphodiesterase
D9C14_RS09460	COG2271	Major facilitator Superfamily
D9C14_RS09475	COG0456	acetyltransferase
D9C14_RS09475	COG1846	Transcriptional regulator
D9C14_RS09480	COG2271	Major facilitator Superfamily
D9C14_RS09490	COG3409	Peptidoglycan-binding domain 1 protein
D9C14_RS09495	COG0697	spore germination
D9C14_RS09500	COG1917	Cupin 2, conserved barrel domain protein
D9C14_RS09500	COG2207	Transcriptional regulator
D9C14_RS09505	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D9C14_RS09510	COG3591	Belongs to the peptidase S1B family
D9C14_RS09520	COG0596	Alpha beta hydrolase
D9C14_RS09525	COG1183	phosphatidylcholine synthase activity
D9C14_RS09530	COG0586	Pfam SNARE associated Golgi protein
D9C14_RS09535	COG0688	phosphatidylethanolamine metabolic process
D9C14_RS09545	COG1054	Belongs to the UPF0176 family
D9C14_RS09550	COG1301	dicarboxylic acid transport
D9C14_RS09555	COG1263	PTS System
D9C14_RS09555	COG2190	(PTS) system
D9C14_RS09555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C14_RS09560	COG0363	glucosamine-6-phosphate deaminase activity
D9C14_RS09565	COG2188	Transcriptional regulator
D9C14_RS09575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C14_RS09580	COG0833	amino acid
D9C14_RS09585	COG2040	homocysteine
D9C14_RS09595	COG1115	amino acid carrier protein
D9C14_RS09600	COG2066	Belongs to the glutaminase family
D9C14_RS09605	COG4191	Histidine kinase
D9C14_RS09610	COG0784	Response regulator, receiver
D9C14_RS09620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9C14_RS09625	COG1012	belongs to the aldehyde dehydrogenase family
D9C14_RS09630	COG2271	Major facilitator Superfamily
D9C14_RS09635	COG4948	Mandelate Racemase Muconate Lactonizing
D9C14_RS09640	COG2186	Transcriptional regulator
D9C14_RS09645	COG2721	sulfolactate sulfo-lyase activity
D9C14_RS09650	COG3173	Aminoglycoside phosphotransferase
D9C14_RS09660	COG0697	spore germination
D9C14_RS09665	COG0745	RESPONSE REGULATOR receiver
D9C14_RS09670	COG2205	protein histidine kinase activity
D9C14_RS09675	COG1131	(ABC) transporter
D9C14_RS09695	COG3773	Cell wall hydrolase
D9C14_RS09700	COG2304	oxidoreductase activity
D9C14_RS09710	COG3540	Alkaline phosphatase
D9C14_RS09715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C14_RS09720	COG0805	protein transport
D9C14_RS09725	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D9C14_RS09730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9C14_RS09735	COG0477	Major facilitator Superfamily
D9C14_RS09740	COG1309	transcriptional regulator
D9C14_RS09745	COG0252	asparaginase activity
D9C14_RS09750	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9C14_RS09755	COG1714	RDD family
D9C14_RS09760	COG3012	SEC-C Motif Domain Protein
D9C14_RS09760	COG1405	negative regulation of cell septum assembly
D9C14_RS09765	COG3290	protein histidine kinase activity
D9C14_RS09770	COG3279	Response regulator of the LytR AlgR family
D9C14_RS09775	COG4555	ABC transporter
D9C14_RS09780	COG1668	transmembrane transport
D9C14_RS09785	COG0667	Aldo Keto reductase
D9C14_RS09800	COG1595	DNA-templated transcription, initiation
D9C14_RS09805	COG1595	DNA-templated transcription, initiation
D9C14_RS09810	COG1876	peptidase activity
D9C14_RS09815	COG0457	Tetratricopeptide repeat
D9C14_RS09820	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS09825	COG0366	Alpha amylase catalytic
D9C14_RS09830	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9C14_RS09835	COG1121	(ABC) transporter
D9C14_RS09840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C14_RS09845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C14_RS09850	COG2310	stress, protein
D9C14_RS09855	COG2310	stress, protein
D9C14_RS09860	COG2310	stress, protein
D9C14_RS09865	COG0861	Integral membrane protein TerC family
D9C14_RS09875	COG3853	Toxic anion resistance protein (TelA)
D9C14_RS09880	COG0477	Major facilitator Superfamily
D9C14_RS09890	COG2814	Major facilitator Superfamily
D9C14_RS09895	COG0640	Transcriptional regulator
D9C14_RS09900	COG0517	IMP dehydrogenase activity
D9C14_RS09900	COG4175	Glycine betaine
D9C14_RS09905	COG4176	ABC-type proline glycine betaine transport system permease component
D9C14_RS09910	COG2113	Glycine betaine
D9C14_RS09915	COG1473	amidohydrolase
D9C14_RS09920	COG1288	antiporter activity
D9C14_RS09930	COG0366	Alpha amylase catalytic
D9C14_RS09935	COG0039	L-malate dehydrogenase activity
D9C14_RS09940	COG1620	l-lactate permease
D9C14_RS09945	COG2814	Major facilitator Superfamily
D9C14_RS09950	COG1846	Transcriptional regulator
D9C14_RS09955	COG1280	lysine exporter protein (LysE YggA)
D9C14_RS09960	COG3403	YqcI/YcgG family
D9C14_RS09965	COG1113	amino acid transport
D9C14_RS09970	COG3665	Urea carboxylase-associated protein
D9C14_RS09975	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D9C14_RS09980	COG1660	Displays ATPase and GTPase activities
D9C14_RS09985	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9C14_RS09990	COG2226	methyltransferase
D9C14_RS09995	COG0583	DNA-binding transcription factor activity
D9C14_RS10000	COG3458	cephalosporin-C deacetylase activity
D9C14_RS10005	COG3541	Predicted nucleotidyltransferase
D9C14_RS10010	COG0506	proline dehydrogenase activity
D9C14_RS10015	COG1012	belongs to the aldehyde dehydrogenase family
D9C14_RS10020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C14_RS10025	COG2508	Transcriptional regulator
D9C14_RS10030	COG3689	TIGRFAM TIGR03943 family protein
D9C14_RS10035	COG0701	Predicted permease
D9C14_RS10040	COG2267	carboxylic ester hydrolase activity
D9C14_RS10045	COG0492	ferredoxin-NADP+ reductase activity
D9C14_RS10050	COG1587	Uroporphyrinogen-III synthase
D9C14_RS10050	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9C14_RS10055	COG2146	nitrite reductase [NAD(P)H] activity
D9C14_RS10060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C14_RS10065	COG0243	molybdopterin cofactor binding
D9C14_RS10070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C14_RS10075	COG2223	nitrite transmembrane transporter activity
D9C14_RS10080	COG1469	GTP cyclohydrolase I activity
D9C14_RS10085	COG1376	ErfK ybiS ycfS ynhG family protein
D9C14_RS10095	COG0523	cobalamin synthesis protein
D9C14_RS10100	COG0765	amino acid transport
D9C14_RS10105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C14_RS10115	COG1714	RDD family
D9C14_RS10125	COG2723	6-phospho-beta-galactosidase activity
D9C14_RS10135	COG3209	COG3209 Rhs family protein
D9C14_RS10140	COG3290	protein histidine kinase activity
D9C14_RS10140	COG0840	transmembrane signaling receptor activity
D9C14_RS10145	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D9C14_RS10150	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D9C14_RS10155	COG1733	regulation of RNA biosynthetic process
D9C14_RS10160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C14_RS10165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C14_RS10170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C14_RS10175	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D9C14_RS10180	COG2814	Major facilitator Superfamily
D9C14_RS10190	COG0697	spore germination
D9C14_RS10205	COG2364	Membrane
D9C14_RS10210	COG1126	abc transporter atp-binding protein
D9C14_RS10215	COG0765	amino acid transport
D9C14_RS10220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C14_RS10225	COG0583	DNA-binding transcription factor activity
D9C14_RS10230	COG0163	prenyltransferase activity
D9C14_RS10235	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D9C14_RS10250	COG0596	Alpha beta hydrolase
D9C14_RS10255	COG3104	oligopeptide transport
D9C14_RS10260	COG5434	Belongs to the glycosyl hydrolase 28 family
D9C14_RS10270	COG0697	spore germination
D9C14_RS10280	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9C14_RS10285	COG1136	(ABC) transporter
D9C14_RS10295	COG0745	RESPONSE REGULATOR receiver
D9C14_RS10300	COG3850	Histidine kinase
D9C14_RS10300	COG5002	protein histidine kinase activity
D9C14_RS10305	COG0457	Tetratricopeptide repeat
D9C14_RS10325	COG0527	aspartate kinase activity
D9C14_RS10330	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C14_RS10335	COG4605	iron ion homeostasis
D9C14_RS10340	COG4604	ABC transporter, ATP-binding protein
D9C14_RS10345	COG4607	ABC-type enterochelin transport system periplasmic component
D9C14_RS10350	COG2814	Major facilitator Superfamily
D9C14_RS10355	COG1309	transcriptional regulator
D9C14_RS10360	COG0778	Nitroreductase
D9C14_RS10365	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9C14_RS10370	COG0640	Transcriptional regulator
D9C14_RS10375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C14_RS10380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D9C14_RS10385	COG1012	belongs to the aldehyde dehydrogenase family
D9C14_RS10390	COG4975	Glucose uptake
D9C14_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS10400	COG4549	nuclear export factor GLE1
D9C14_RS10405	COG1276	copper resistance
D9C14_RS10405	COG2372	response to copper ion
D9C14_RS10410	COG1349	DNA-binding transcription factor activity
D9C14_RS10420	COG2213	PTS system mannitol-specific
D9C14_RS10425	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C14_RS10430	COG0246	Mannitol dehydrogenase
D9C14_RS10435	COG0473	3-isopropylmalate dehydrogenase activity
D9C14_RS10440	COG0681	Belongs to the peptidase S26 family
D9C14_RS10445	COG0412	Dienelactone hydrolase
D9C14_RS10450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9C14_RS10460	COG0561	phosphatase activity
D9C14_RS10465	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D9C14_RS10470	COG1914	H( )-stimulated, divalent metal cation uptake system
D9C14_RS10475	COG4336	lyase activity
D9C14_RS10480	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D9C14_RS10485	COG1984	allophanate hydrolase subunit 2
D9C14_RS10490	COG1414	Transcriptional regulator
D9C14_RS10495	COG2755	lipolytic protein G-D-S-L family
D9C14_RS10505	COG2329	Antibiotic biosynthesis monooxygenase
D9C14_RS10510	COG0768	penicillin binding
D9C14_RS10515	COG4989	oxidoreductase activity
D9C14_RS10520	COG3711	transcriptional antiterminator
D9C14_RS10525	COG0318	PFAM AMP-dependent synthetase and ligase
D9C14_RS10530	COG2226	methyltransferase
D9C14_RS10535	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS10540	COG1917	Cupin 2, conserved barrel domain protein
D9C14_RS10545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C14_RS10550	COG3871	stress protein (general stress protein 26)
D9C14_RS10560	COG2814	Major facilitator Superfamily
D9C14_RS10565	COG1522	sequence-specific DNA binding
D9C14_RS10570	COG0551	DNA topoisomerase type I activity
D9C14_RS10570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9C14_RS10575	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D9C14_RS10580	COG3706	GGDEF domain
D9C14_RS10585	COG5298	Protein conserved in bacteria
D9C14_RS10590	COG1215	transferase activity, transferring glycosyl groups
D9C14_RS10600	COG0531	amino acid
D9C14_RS10605	COG0494	nUDIX hydrolase
D9C14_RS10610	COG0028	Belongs to the TPP enzyme family
D9C14_RS10625	COG1914	H( )-stimulated, divalent metal cation uptake system
D9C14_RS10630	COG2261	transglycosylase associated protein
D9C14_RS10635	COG4876	unkown
D9C14_RS10640	COG2217	Heavy metal translocating P-type atpase
D9C14_RS10645	COG3729	General stress protein
D9C14_RS10650	COG0662	Cupin 2, conserved barrel domain protein
D9C14_RS10655	COG2329	Antibiotic biosynthesis monooxygenase
D9C14_RS10660	COG3546	catalase activity
D9C14_RS10665	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D9C14_RS10670	COG3290	protein histidine kinase activity
D9C14_RS10675	COG4565	transcriptional regulatory protein
D9C14_RS10680	COG1301	dicarboxylic acid transport
D9C14_RS10685	COG0628	permease
D9C14_RS10690	COG1131	(ABC) transporter
D9C14_RS10695	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C14_RS10705	COG1960	acyl-CoA dehydrogenase activity
D9C14_RS10720	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C14_RS10725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C14_RS10730	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9C14_RS10735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D9C14_RS10745	COG0513	Belongs to the DEAD box helicase family
D9C14_RS10750	COG3402	PFAM membrane-flanked domain
D9C14_RS10755	COG3428	Bacterial PH domain
D9C14_RS10760	COG0705	Rhomboid family
D9C14_RS10765	COG0736	holo-[acyl-carrier-protein] synthase activity
D9C14_RS10770	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D9C14_RS10775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9C14_RS10780	COG0864	Transcriptional regulator
D9C14_RS10785	COG2337	Toxic component of a toxin-antitoxin (TA) module
D9C14_RS10790	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C14_RS10795	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C14_RS10800	COG2172	sigma factor antagonist activity
D9C14_RS10805	COG2208	phosphoserine phosphatase activity
D9C14_RS10810	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C14_RS10815	COG2172	sigma factor antagonist activity
D9C14_RS10820	COG1191	sigma factor activity
D9C14_RS10825	COG2208	phosphoserine phosphatase activity
D9C14_RS10830	COG2183	response to ionizing radiation
D9C14_RS10840	COG3091	SprT-like family
D9C14_RS10885	COG1476	TRANSCRIPTIONal
D9C14_RS10910	COG0693	protein deglycase activity
D9C14_RS10915	COG1278	Cold shock
D9C14_RS10920	COG1329	Transcriptional regulator
D9C14_RS10930	COG0697	spore germination
D9C14_RS10935	COG1917	Cupin 2, conserved barrel domain protein
D9C14_RS10935	COG2207	Transcriptional regulator
D9C14_RS10940	COG0697	spore germination
D9C14_RS10945	COG2207	Transcriptional regulator
D9C14_RS10945	COG3708	Transcriptional regulator
D9C14_RS10950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C14_RS10955	COG0477	Major facilitator Superfamily
D9C14_RS10965	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D9C14_RS10980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C14_RS10985	COG1309	transcriptional regulator
D9C14_RS10990	COG0697	spore germination
D9C14_RS10995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C14_RS11000	COG2030	dehydratase
D9C14_RS11005	COG3545	Serine hydrolase
D9C14_RS11010	COG1733	regulation of RNA biosynthetic process
D9C14_RS11015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C14_RS11020	COG2814	Major facilitator Superfamily
D9C14_RS11025	COG1309	transcriptional regulator
D9C14_RS11035	COG0640	Transcriptional regulator
D9C14_RS11040	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9C14_RS11050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C14_RS11055	COG0697	spore germination
D9C14_RS11060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C14_RS11065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9C14_RS11070	COG0640	Transcriptional regulator
D9C14_RS11075	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9C14_RS11090	COG4585	Histidine kinase
D9C14_RS11095	COG2197	response regulator
D9C14_RS11100	COG2409	Drug exporters of the RND superfamily
D9C14_RS11105	COG0596	Alpha beta hydrolase
D9C14_RS11110	COG1811	Na channel or pump
D9C14_RS11115	COG0789	Transcriptional regulator
D9C14_RS11115	COG4978	Transcriptional regulator
D9C14_RS11120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C14_RS11125	COG0778	Nitroreductase
D9C14_RS11130	COG0346	lactoylglutathione lyase activity
D9C14_RS11135	COG2259	Doxx family
D9C14_RS11140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C14_RS11155	COG2323	membrane
D9C14_RS11160	COG2323	membrane
D9C14_RS11165	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C14_RS11180	COG1309	transcriptional regulator
D9C14_RS11190	COG0456	acetyltransferase
D9C14_RS11195	COG0488	(ABC) transporter
D9C14_RS11200	COG1113	amino acid transport
D9C14_RS11205	COG2318	DinB family
D9C14_RS11210	COG1846	Transcriptional regulator
D9C14_RS11215	COG2409	Drug exporters of the RND superfamily
D9C14_RS11215	COG1033	growth of symbiont in host cell
D9C14_RS11220	COG0778	Nitroreductase
D9C14_RS11225	COG1846	Transcriptional regulator
D9C14_RS11230	COG2814	Major facilitator Superfamily
D9C14_RS11235	COG0730	response to heat
D9C14_RS11240	COG1802	Transcriptional regulator
D9C14_RS11245	COG3858	chitin binding
D9C14_RS11245	COG1388	LysM domain
D9C14_RS11250	COG1819	glycosyl
D9C14_RS11260	COG1785	Belongs to the alkaline phosphatase family
D9C14_RS11265	COG5646	InterPro IPR014922
D9C14_RS11275	COG0454	-acetyltransferase
D9C14_RS11280	COG1078	dGTPase activity
D9C14_RS11285	COG1388	LysM domain
D9C14_RS11290	COG2814	Major facilitator Superfamily
D9C14_RS11295	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C14_RS11300	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9C14_RS11305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C14_RS11310	COG2723	6-phospho-beta-galactosidase activity
D9C14_RS11315	COG2188	Transcriptional regulator
D9C14_RS11320	COG1940	carbohydrate kinase activity
D9C14_RS11325	COG1482	cell wall glycoprotein biosynthetic process
D9C14_RS11330	COG4124	Belongs to the glycosyl hydrolase 26 family
D9C14_RS11375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D9C14_RS11380	COG0802	atpase or kinase
D9C14_RS11385	COG1214	PFAM Peptidase M22, glycoprotease
D9C14_RS11390	COG0456	acetyltransferase
D9C14_RS11395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D9C14_RS11400	COG0488	(ABC) transporter
D9C14_RS11405	COG0315	cyclic pyranopterin monophosphate synthase activity
D9C14_RS11410	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D9C14_RS11415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C14_RS11420	COG0805	protein transport
D9C14_RS11435	COG1266	CAAX protease self-immunity
D9C14_RS11445	COG0459	protein refolding
D9C14_RS11455	COG1073	alpha beta
D9C14_RS11460	COG0457	Tetratricopeptide repeat
D9C14_RS11465	COG1063	alcohol dehydrogenase
D9C14_RS11470	COG2211	Major facilitator Superfamily
D9C14_RS11475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C14_RS11480	COG1842	Phage shock protein A
D9C14_RS11485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9C14_RS11490	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D9C14_RS11495	COG4260	virion core protein, lumpy skin disease virus
D9C14_RS11505	COG2814	Major facilitator Superfamily
D9C14_RS11510	COG1063	alcohol dehydrogenase
D9C14_RS11515	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D9C14_RS11520	COG0823	Involved in the tonB-independent uptake of proteins
D9C14_RS11535	COG2267	carboxylic ester hydrolase activity
D9C14_RS11545	COG2132	Multicopper oxidase
D9C14_RS11550	COG1113	amino acid transport
D9C14_RS11560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C14_RS11565	COG0714	Associated with various cellular activities
D9C14_RS11570	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D9C14_RS11575	COG1305	Transglutaminase-like
D9C14_RS11580	COG0519	Catalyzes the synthesis of GMP from XMP
D9C14_RS11580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D9C14_RS11585	COG2252	PERMEase
D9C14_RS11590	COG3064	Membrane
D9C14_RS11600	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D9C14_RS11610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D9C14_RS11615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D9C14_RS11620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D9C14_RS11625	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D9C14_RS11630	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9C14_RS11635	COG0047	phosphoribosylformylglycinamidine synthase activity
D9C14_RS11640	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9C14_RS11645	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D9C14_RS11650	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D9C14_RS11655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D9C14_RS11660	COG0138	bifunctional purine biosynthesis protein purh
D9C14_RS11665	COG0151	Belongs to the GarS family
D9C14_RS11670	COG1522	sequence-specific DNA binding
D9C14_RS11675	COG0531	amino acid
D9C14_RS11685	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9C14_RS11690	COG1470	cell adhesion involved in biofilm formation
D9C14_RS11695	COG4496	protein, YerC YecD
D9C14_RS11700	COG0069	glutamate synthase activity
D9C14_RS11705	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D9C14_RS11710	COG0210	DNA helicase
D9C14_RS11715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D9C14_RS11720	COG4851	CamS sex pheromone cAM373 precursor
D9C14_RS11725	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C14_RS11730	COG1285	pathogenesis
D9C14_RS11735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C14_RS11740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9C14_RS11745	COG0154	amidase activity
D9C14_RS11750	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9C14_RS11755	COG1309	transcriptional regulator
D9C14_RS11760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9C14_RS11765	COG1597	lipid kinase activity
D9C14_RS11770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9C14_RS11780	COG0457	Tetratricopeptide repeat
D9C14_RS11795	COG5444	nuclease activity
D9C14_RS11800	COG3391	amine dehydrogenase activity
D9C14_RS11805	COG0457	Tetratricopeptide repeat
D9C14_RS11815	COG0217	transcriptional regulatory protein
D9C14_RS11825	COG1309	transcriptional regulator
D9C14_RS11830	COG3631	Ketosteroid isomerase-related protein
D9C14_RS11835	COG0702	epimerase
D9C14_RS11850	COG3546	catalase activity
D9C14_RS11855	COG0454	-acetyltransferase
D9C14_RS11865	COG5578	integral membrane protein
D9C14_RS11870	COG2972	Histidine kinase
D9C14_RS11875	COG2207	Transcriptional regulator
D9C14_RS11875	COG4753	response regulator
D9C14_RS11880	COG1653	transport
D9C14_RS11885	COG1175	transmembrane transport
D9C14_RS11890	COG0395	ABC-type sugar transport system, permease component
D9C14_RS11895	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9C14_RS11900	COG2207	Transcriptional regulator
D9C14_RS11905	COG2755	lipolytic protein G-D-S-L family
D9C14_RS11915	COG5578	integral membrane protein
D9C14_RS11920	COG3401	FG-GAP repeat protein
D9C14_RS11925	COG3401	FG-GAP repeat protein
D9C14_RS11930	COG2755	lipolytic protein G-D-S-L family
D9C14_RS11935	COG1874	Beta-galactosidase
D9C14_RS11945	COG1653	transport
D9C14_RS11950	COG4209	transmembrane transport
D9C14_RS11955	COG0395	ABC-type sugar transport system, permease component
D9C14_RS11960	COG1486	melibiose metabolic process
D9C14_RS11965	COG2323	membrane
D9C14_RS11970	COG2329	Antibiotic biosynthesis monooxygenase
D9C14_RS11975	COG0346	lactoylglutathione lyase activity
D9C14_RS11990	COG5583	Uncharacterized small protein (DUF2292)
D9C14_RS11995	COG0670	Belongs to the BI1 family
D9C14_RS12000	COG0697	spore germination
D9C14_RS12005	COG1846	Transcriptional regulator
D9C14_RS12010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9C14_RS12025	COG2124	cytochrome p450
D9C14_RS12025	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C14_RS12040	COG1368	sulfuric ester hydrolase activity
D9C14_RS12045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D9C14_RS12050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C14_RS12055	COG1442	glycosyl transferase family 8
D9C14_RS12060	COG1216	Glycosyl transferase, family 2
D9C14_RS12065	COG1442	glycosyl transferase family 8
D9C14_RS12070	COG2223	nitrite transmembrane transporter activity
D9C14_RS12075	COG1011	Hydrolase
D9C14_RS12080	COG0531	amino acid
D9C14_RS12085	COG1012	belongs to the aldehyde dehydrogenase family
D9C14_RS12090	COG0840	transmembrane signaling receptor activity
D9C14_RS12095	COG0488	(ABC) transporter
D9C14_RS12105	COG0789	Transcriptional regulator
D9C14_RS12110	COG2814	Major facilitator Superfamily
D9C14_RS12120	COG0488	(ABC) transporter
D9C14_RS12125	COG0513	Belongs to the DEAD box helicase family
D9C14_RS12130	COG0456	acetyltransferase
D9C14_RS12135	COG2130	NADP-dependent
D9C14_RS12145	COG2211	Major facilitator Superfamily
D9C14_RS12150	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D9C14_RS12155	COG1120	ATPase activity
D9C14_RS12160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C14_RS12165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C14_RS12170	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D9C14_RS12185	COG3866	Pectate lyase
D9C14_RS12190	COG0471	metal ion transport
D9C14_RS12195	COG3290	protein histidine kinase activity
D9C14_RS12200	COG4565	transcriptional regulatory protein
D9C14_RS12205	COG3181	Tripartite tricarboxylate transporter family receptor
D9C14_RS12210	COG2851	Citrate transporter
D9C14_RS12215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C14_RS12220	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D9C14_RS12225	COG1254	Belongs to the acylphosphatase family
D9C14_RS12230	COG2258	MOSC domain
D9C14_RS12250	COG0024	Methionine aminopeptidase
D9C14_RS12255	COG1263	PTS System
D9C14_RS12255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C14_RS12260	COG1368	sulfuric ester hydrolase activity
D9C14_RS12275	COG1115	amino acid carrier protein
D9C14_RS12280	COG0531	amino acid
D9C14_RS12300	COG1263	PTS System
D9C14_RS12300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C14_RS12305	COG0366	Alpha amylase catalytic
D9C14_RS12310	COG2188	Transcriptional regulator
D9C14_RS12315	COG0778	Nitroreductase
D9C14_RS12320	COG0737	Belongs to the 5'-nucleotidase family
D9C14_RS12325	COG0693	protein deglycase activity
D9C14_RS12330	COG2814	Major facilitator Superfamily
D9C14_RS12335	COG4840	Belongs to the UPF0435 family
D9C14_RS12340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C14_RS12345	COG4980	gas vesicle protein
D9C14_RS12350	COG1295	ribonuclease BN
D9C14_RS12355	COG0477	Major facilitator Superfamily
D9C14_RS12360	COG0387	Pfam Sodium calcium exchanger
D9C14_RS12370	COG0668	transmembrane transport
D9C14_RS12375	COG0535	radical SAM domain protein
D9C14_RS12385	COG0726	polysaccharide deacetylase
D9C14_RS12390	COG2084	Dehydrogenase
D9C14_RS12395	COG0598	Magnesium transport protein CorA
D9C14_RS12400	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9C14_RS12405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9C14_RS12415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9C14_RS12420	COG4637	Psort location Cytoplasmic, score
D9C14_RS12425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C14_RS12430	COG0022	dehydrogenase e1 component
D9C14_RS12435	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C14_RS12440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C14_RS12445	COG3284	Transcriptional regulator
D9C14_RS12455	COG1742	UPF0060 membrane protein
D9C14_RS12475	COG4842	Belongs to the WXG100 family
D9C14_RS12480	COG1486	melibiose metabolic process
D9C14_RS12485	COG1737	Transcriptional regulator
D9C14_RS12490	COG1263	PTS System
D9C14_RS12490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C14_RS12495	COG5434	Belongs to the glycosyl hydrolase 28 family
D9C14_RS12500	COG1132	(ABC) transporter
D9C14_RS12505	COG1132	(ABC) transporter
D9C14_RS12510	COG2259	Doxx family
D9C14_RS12515	COG2514	catechol 2,3-dioxygenase activity
D9C14_RS12520	COG4585	Histidine kinase
D9C14_RS12525	COG2197	response regulator
D9C14_RS12530	COG1131	(ABC) transporter
D9C14_RS12535	COG1511	domain protein
D9C14_RS12535	COG0842	Transport permease protein
D9C14_RS12540	COG0842	Transport permease protein
D9C14_RS12545	COG1695	Transcriptional regulator
D9C14_RS12550	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9C14_RS12555	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D9C14_RS12560	COG2318	DinB family
D9C14_RS12565	COG2814	Major facilitator Superfamily
D9C14_RS12570	COG1846	Transcriptional regulator
D9C14_RS12575	COG0392	lysyltransferase activity
D9C14_RS12575	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D9C14_RS12580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C14_RS12585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C14_RS12590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C14_RS12595	COG0384	phenazine biosynthesis protein PhzF
D9C14_RS12600	COG0778	Nitroreductase
D9C14_RS12615	COG1090	epimerase
D9C14_RS12620	COG2137	regulation of response to DNA damage stimulus
D9C14_RS12630	COG2814	Major facilitator Superfamily
D9C14_RS12645	COG3103	Sh3 type 3 domain protein
D9C14_RS12650	COG5658	integral membrane protein
D9C14_RS12655	COG0596	Alpha beta hydrolase
D9C14_RS12660	COG0463	Glycosyl transferase, family 2
D9C14_RS12665	COG4485	Bacterial membrane protein, YfhO
D9C14_RS12670	COG1988	membrane-bound metal-dependent
D9C14_RS12675	COG1194	a g-specific adenine glycosylase
D9C14_RS12685	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS12700	COG3557	Belongs to the UPF0374 family
D9C14_RS12705	COG1132	(ABC) transporter
D9C14_RS12710	COG4129	membrane
D9C14_RS12715	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9C14_RS12720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D9C14_RS12725	COG0735	belongs to the Fur family
D9C14_RS12835	COG4326	sporulation control protein
D9C14_RS12845	COG5577	PFAM Coat F domain
D9C14_RS12850	COG3340	Belongs to the peptidase S51 family
D9C14_RS12855	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D9C14_RS12860	COG0277	FAD linked oxidase domain protein
D9C14_RS12870	COG0753	catalase activity
D9C14_RS12875	COG1116	anion transmembrane transporter activity
D9C14_RS12880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9C14_RS12885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9C14_RS12890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C14_RS12900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9C14_RS12910	COG1476	TRANSCRIPTIONal
D9C14_RS12920	COG3382	B3 4 domain protein
D9C14_RS12925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D9C14_RS12935	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D9C14_RS12940	COG0789	Transcriptional regulator
D9C14_RS12945	COG1664	Polymer-forming cytoskeletal
D9C14_RS12950	COG1664	Polymer-forming cytoskeletal
D9C14_RS12955	COG2766	serine protein kinase
D9C14_RS12960	COG2718	Belongs to the UPF0229 family
D9C14_RS12965	COG1846	Transcriptional regulator
D9C14_RS12970	COG1566	PFAM secretion protein HlyD family protein
D9C14_RS12975	COG2814	Major facilitator Superfamily
D9C14_RS12980	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9C14_RS13000	COG1725	Transcriptional regulator
D9C14_RS13005	COG1131	(ABC) transporter
D9C14_RS13010	COG1131	(ABC) transporter
D9C14_RS13015	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C14_RS13020	COG1278	Cold shock
D9C14_RS13030	COG1464	Belongs to the NlpA lipoprotein family
D9C14_RS13035	COG3706	GGDEF domain
D9C14_RS13040	COG1823	symporter activity
D9C14_RS13060	COG5577	PFAM Coat F domain
D9C14_RS13065	COG0737	Belongs to the 5'-nucleotidase family
D9C14_RS13065	COG4085	toxin activity
D9C14_RS13065	COG1525	nuclease
D9C14_RS13070	COG3764	Sortase (surface protein transpeptidase)
D9C14_RS13075	COG0564	pseudouridine synthase activity
D9C14_RS13085	COG0517	IMP dehydrogenase activity
D9C14_RS13090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9C14_RS13095	COG3153	acetyltransferase
D9C14_RS13095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9C14_RS13100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C14_RS13105	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D9C14_RS13110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9C14_RS13115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D9C14_RS13120	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9C14_RS13125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9C14_RS13130	COG4585	Histidine kinase
D9C14_RS13130	COG2203	Gaf domain
D9C14_RS13135	COG2197	response regulator
D9C14_RS13140	COG0431	NADPH-dependent FMN reductase
D9C14_RS13155	COG0791	NLP P60 protein
D9C14_RS13155	COG1388	LysM domain
D9C14_RS13160	COG1959	2 iron, 2 sulfur cluster binding
D9C14_RS13165	COG0668	transmembrane transport
D9C14_RS13170	COG2719	SpoVR family
D9C14_RS13175	COG1785	Belongs to the alkaline phosphatase family
D9C14_RS13180	COG0791	NLP P60 protein
D9C14_RS13180	COG1388	LysM domain
D9C14_RS13185	COG0583	DNA-binding transcription factor activity
D9C14_RS13190	COG0372	Belongs to the citrate synthase family
D9C14_RS13195	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS13200	COG0531	amino acid
D9C14_RS13205	COG0733	neurotransmitter:sodium symporter activity
D9C14_RS13210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C14_RS13230	COG1595	DNA-templated transcription, initiation
D9C14_RS13235	COG0667	Aldo Keto reductase
D9C14_RS13240	COG0204	Acyl-transferase
D9C14_RS13245	COG1253	flavin adenine dinucleotide binding
D9C14_RS13250	COG0789	Transcriptional regulator
D9C14_RS13255	COG0436	Aminotransferase
D9C14_RS13260	COG1253	flavin adenine dinucleotide binding
D9C14_RS13265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9C14_RS13270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9C14_RS13275	COG0584	glycerophosphoryl diester phosphodiesterase
D9C14_RS13285	COG0668	transmembrane transport
D9C14_RS13290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D9C14_RS13295	COG0726	polysaccharide deacetylase
D9C14_RS13300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C14_RS13305	COG1757	Na H antiporter
D9C14_RS13310	COG0589	response to stress
D9C14_RS13320	COG1132	(ABC) transporter
D9C14_RS13325	COG1132	(ABC) transporter
D9C14_RS13330	COG0702	epimerase
D9C14_RS13350	COG0189	ligase activity
D9C14_RS13355	COG0189	ligase activity
D9C14_RS13360	COG4399	Belongs to the UPF0754 family
D9C14_RS13365	COG3679	Belongs to the UPF0342 family
D9C14_RS13370	COG4335	DNA alkylation repair
D9C14_RS13375	COG0561	phosphatase activity
D9C14_RS13380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9C14_RS13385	COG0475	glutathione-regulated potassium exporter activity
D9C14_RS13390	COG0490	domain, Protein
D9C14_RS13400	COG1024	Enoyl-CoA hydratase
D9C14_RS13410	COG4152	abc transporter atp-binding protein
D9C14_RS13415	COG1668	transmembrane transport
D9C14_RS13420	COG0420	3'-5' exonuclease activity
D9C14_RS13425	COG4717	serine-type aminopeptidase activity
D9C14_RS13430	COG3481	metal-dependent phosphohydrolase, HD sub domain
D9C14_RS13440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9C14_RS13470	COG1846	Transcriptional regulator
D9C14_RS13475	COG4980	gas vesicle protein
D9C14_RS13490	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D9C14_RS13495	COG0537	adenosine 5'-monophosphoramidase activity
D9C14_RS13500	COG1131	(ABC) transporter
D9C14_RS13505	COG4473	ABC transporter
D9C14_RS13515	COG1473	amidohydrolase
D9C14_RS13520	COG3069	C4-dicarboxylate transmembrane transporter activity
D9C14_RS13530	COG2329	Antibiotic biosynthesis monooxygenase
D9C14_RS13535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C14_RS13540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D9C14_RS13545	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D9C14_RS13550	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D9C14_RS13555	COG1309	transcriptional regulator
D9C14_RS13560	COG1511	domain protein
D9C14_RS13565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C14_RS13570	COG4377	Putative membrane peptidase family (DUF2324)
D9C14_RS13580	COG1363	Peptidase, m42
D9C14_RS13585	COG4405	Protein conserved in bacteria
D9C14_RS13590	COG1301	dicarboxylic acid transport
D9C14_RS13600	COG1234	tRNA 3'-trailer cleavage
D9C14_RS13605	COG0095	Lipoate-protein ligase
D9C14_RS13610	COG0702	epimerase
D9C14_RS13615	COG0318	PFAM AMP-dependent synthetase and ligase
D9C14_RS13625	COG0501	Belongs to the peptidase M48B family
D9C14_RS13630	COG1404	Belongs to the peptidase S8 family
D9C14_RS13640	COG0604	alcohol dehydrogenase
D9C14_RS13645	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D9C14_RS13650	COG0406	alpha-ribazole phosphatase activity
D9C14_RS13655	COG0183	Belongs to the thiolase family
D9C14_RS13660	COG0318	PFAM AMP-dependent synthetase and ligase
D9C14_RS13665	COG1268	BioY protein
D9C14_RS13670	COG0840	transmembrane signaling receptor activity
D9C14_RS13675	COG0723	plastoquinol--plastocyanin reductase activity
D9C14_RS13675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C14_RS13680	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS13690	COG4903	ComK protein
D9C14_RS13695	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS13705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C14_RS13720	COG0398	Pfam SNARE associated Golgi protein
D9C14_RS13725	COG0681	Belongs to the peptidase S26 family
D9C14_RS13730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9C14_RS13735	COG1846	Transcriptional regulator
D9C14_RS13740	COG0738	Major facilitator superfamily
D9C14_RS13745	COG0673	inositol 2-dehydrogenase activity
D9C14_RS13750	COG0561	phosphatase activity
D9C14_RS13755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C14_RS13760	COG1609	Transcriptional regulator
D9C14_RS13765	COG3180	Ammonia monooxygenase
D9C14_RS13770	COG0477	Major facilitator Superfamily
D9C14_RS13770	COG2814	Major facilitator Superfamily
D9C14_RS13775	COG4533	DNA binding
D9C14_RS13785	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D9C14_RS13790	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D9C14_RS13795	COG1074	ATP-dependent DNA helicase activity
D9C14_RS13800	COG0420	3'-5' exonuclease activity
D9C14_RS13805	COG0419	ATPase involved in DNA repair
D9C14_RS13810	COG1403	HNH endonuclease
D9C14_RS13850	COG5337	Spore coat protein CotH
D9C14_RS13855	COG0179	Fumarylacetoacetate (FAA) hydrolase
D9C14_RS13865	COG1404	Belongs to the peptidase S8 family
D9C14_RS13875	COG0367	asparagine synthase
D9C14_RS13880	COG2318	DinB family
D9C14_RS13885	COG1562	ergosterol biosynthetic process
D9C14_RS13890	COG0534	Mate efflux family protein
D9C14_RS13895	COG2207	Transcriptional regulator
D9C14_RS13895	COG1917	Cupin 2, conserved barrel domain protein
D9C14_RS13900	COG1609	Transcriptional regulator
D9C14_RS13905	COG0673	inositol 2-dehydrogenase activity
D9C14_RS13910	COG2318	DinB family
D9C14_RS13915	COG1279	arginine transmembrane transporter activity
D9C14_RS13920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C14_RS13925	COG1357	PFAM Pentapeptide repeats (8 copies)
D9C14_RS13930	COG2267	carboxylic ester hydrolase activity
D9C14_RS13935	COG0529	Catalyzes the synthesis of activated sulfate
D9C14_RS13940	COG2046	Belongs to the sulfate adenylyltransferase family
D9C14_RS13945	COG0175	sulfate reduction
D9C14_RS13950	COG2045	Belongs to the ComB family
D9C14_RS13955	COG1809	phosphosulfolactate synthase activity
D9C14_RS13960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C14_RS13965	COG4948	Mandelate Racemase Muconate Lactonizing
D9C14_RS13970	COG2814	Major facilitator Superfamily
D9C14_RS13975	COG0454	-acetyltransferase
D9C14_RS13980	COG2153	protein acetylation
D9C14_RS13985	COG0646	methionine synthase
D9C14_RS13985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D9C14_RS13990	COG1666	GTP binding
D9C14_RS13995	COG2996	Protein conserved in bacteria
D9C14_RS14015	COG1695	Transcriptional regulator
D9C14_RS14030	COG3227	Zinc metalloprotease (Elastase)
D9C14_RS14035	COG1307	EDD domain protein, DegV family
D9C14_RS14040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C14_RS14055	COG0561	phosphatase activity
D9C14_RS14060	COG1073	alpha beta
D9C14_RS14065	COG2151	metal-sulfur cluster biosynthetic enzyme
D9C14_RS14075	COG0277	FAD linked oxidase domain protein
D9C14_RS14080	COG2271	Major facilitator Superfamily
D9C14_RS14085	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D9C14_RS14090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D9C14_RS14100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9C14_RS14105	COG0505	Belongs to the CarA family
D9C14_RS14110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9C14_RS14115	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9C14_RS14130	COG2267	carboxylic ester hydrolase activity
D9C14_RS14140	COG1744	ABC transporter substrate-binding protein PnrA-like
D9C14_RS14155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C14_RS14160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9C14_RS14165	COG5504	Zn-dependent protease
D9C14_RS14170	COG0444	Belongs to the ABC transporter superfamily
D9C14_RS14175	COG4608	Belongs to the ABC transporter superfamily
D9C14_RS14185	COG0601	transmembrane transport
D9C14_RS14190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C14_RS14200	COG0180	Tryptophanyl-tRNA synthetase
D9C14_RS14205	COG4166	transmembrane transport
D9C14_RS14210	COG0601	transmembrane transport
D9C14_RS14220	COG0444	Belongs to the ABC transporter superfamily
D9C14_RS14225	COG4608	Belongs to the ABC transporter superfamily
D9C14_RS14230	COG2814	Major facilitator Superfamily
D9C14_RS14235	COG0456	acetyltransferase
D9C14_RS14240	COG1393	Belongs to the ArsC family
D9C14_RS14245	COG0861	Integral membrane protein TerC family
D9C14_RS14255	COG4862	establishment of competence for transformation
D9C14_RS14265	COG4469	Competence protein
D9C14_RS14270	COG1164	Oligoendopeptidase f
D9C14_RS14285	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9C14_RS14290	COG2346	COG2346, Truncated hemoglobins
D9C14_RS14295	COG0741	lytic transglycosylase activity
D9C14_RS14300	COG4116	CYTH
D9C14_RS14310	COG2357	RelA SpoT domain protein
D9C14_RS14315	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9C14_RS14320	COG0564	pseudouridine synthase activity
D9C14_RS14325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D9C14_RS14330	COG0569	domain protein
D9C14_RS14330	COG0475	glutathione-regulated potassium exporter activity
D9C14_RS14335	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D9C14_RS14340	COG0352	thiamine-phosphate diphosphorylase activity
D9C14_RS14345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C14_RS14350	COG2104	thiamine diphosphate biosynthetic process
D9C14_RS14355	COG2022	thiamine diphosphate biosynthetic process
D9C14_RS14360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C14_RS14365	COG0351	phosphomethylpyrimidine kinase
D9C14_RS14370	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D9C14_RS14425	COG0210	DNA helicase
D9C14_RS14435	COG2153	protein acetylation
D9C14_RS14440	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9C14_RS14445	COG2382	esterase
D9C14_RS14450	COG0626	cystathionine gamma-synthase activity
D9C14_RS14455	COG0626	cystathionine gamma-synthase activity
D9C14_RS14465	COG5505	Protein of unknown function (DUF819)
D9C14_RS14490	COG5444	nuclease activity
D9C14_RS14535	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9C14_RS14540	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS14550	COG3711	transcriptional antiterminator
D9C14_RS14550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C14_RS14555	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C14_RS14555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C14_RS14555	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C14_RS14560	COG1482	cell wall glycoprotein biosynthetic process
D9C14_RS14570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C14_RS14580	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D9C14_RS14600	COG0109	protoheme IX farnesyltransferase activity
D9C14_RS14610	COG0726	polysaccharide deacetylase
D9C14_RS14625	COG5504	Zn-dependent protease
D9C14_RS14630	COG2205	protein histidine kinase activity
D9C14_RS14640	COG3383	formate dehydrogenase (NAD+) activity
D9C14_RS14645	COG2427	Protein of unknown function (DUF1641)
D9C14_RS14655	COG1051	belongs to the nudix hydrolase family
D9C14_RS14665	COG2124	cytochrome p450
D9C14_RS14670	COG1819	glycosyl
D9C14_RS14680	COG1587	Uroporphyrinogen-III synthase
D9C14_RS14685	COG0390	transport system, permease component
D9C14_RS14690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C14_RS14695	COG0697	spore germination
D9C14_RS14700	COG4297	protein containing double-stranded beta helix domain
D9C14_RS14710	COG1252	NADH dehydrogenase
D9C14_RS14715	COG1904	glucuronate isomerase
D9C14_RS14720	COG2211	Major facilitator Superfamily
D9C14_RS14725	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D9C14_RS14730	COG1063	alcohol dehydrogenase
D9C14_RS14735	COG1312	Catalyzes the dehydration of D-mannonate
D9C14_RS14740	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS14745	COG2271	Major facilitator Superfamily
D9C14_RS14750	COG1609	Transcriptional regulator
D9C14_RS14755	COG0246	Mannitol dehydrogenase
D9C14_RS14760	COG2721	sulfolactate sulfo-lyase activity
D9C14_RS14765	COG0730	response to heat
D9C14_RS14770	COG2318	DinB family
D9C14_RS14775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9C14_RS14780	COG0457	Tetratricopeptide repeat
D9C14_RS14790	COG2350	Protein conserved in bacteria
D9C14_RS14795	COG1388	LysM domain
D9C14_RS14795	COG3409	Peptidoglycan-binding domain 1 protein
D9C14_RS14795	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C14_RS14805	COG4195	phage-related replication protein
D9C14_RS14810	COG3546	catalase activity
D9C14_RS14815	COG2856	Zn peptidase
D9C14_RS14820	COG1396	sequence-specific DNA binding
D9C14_RS14830	COG1522	sequence-specific DNA binding
D9C14_RS14835	COG1484	DNA-dependent DNA replication
D9C14_RS14855	COG1595	DNA-templated transcription, initiation
D9C14_RS14860	COG3728	DNA packaging
D9C14_RS14860	COG5484	DNA packaging
D9C14_RS14865	COG1783	phage Terminase large subunit
D9C14_RS14870	COG5518	Phage portal protein
D9C14_RS14875	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D9C14_RS14880	COG4653	Phage capsid family
D9C14_RS14930	COG5412	phage tail tape measure protein
D9C14_RS14930	COG3953	SLT domain
D9C14_RS14930	COG5412	phage tail tape measure protein
D9C14_RS14930	COG3953	SLT domain
D9C14_RS14935	COG1652	LysM domain
D9C14_RS14940	COG4193	domain, Protein
D9C14_RS14950	COG3628	GPW Gp25 family protein
D9C14_RS14955	COG3299	homolog of phage Mu protein gp47
D9C14_RS14960	COG3778	Protein conserved in bacteria
D9C14_RS15000	COG3409	Peptidoglycan-binding domain 1 protein
D9C14_RS15000	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C14_RS15020	COG0306	phosphate transporter
D9C14_RS15025	COG1392	Phosphate transport regulator
D9C14_RS15030	COG0531	amino acid
D9C14_RS15035	COG0346	lactoylglutathione lyase activity
D9C14_RS15040	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9C14_RS15045	COG0463	Glycosyl transferase, family 2
D9C14_RS15050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C14_RS15055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C14_RS15060	COG2362	D-Aminopeptidase
D9C14_RS15065	COG0601	transmembrane transport
D9C14_RS15070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C14_RS15075	COG0444	Belongs to the ABC transporter superfamily
D9C14_RS15080	COG4166	transmembrane transport
D9C14_RS15085	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9C14_RS15090	COG4948	Mandelate Racemase Muconate Lactonizing
D9C14_RS15095	COG0791	NLP P60 protein
D9C14_RS15100	COG4608	Belongs to the ABC transporter superfamily
D9C14_RS15105	COG2706	6-phosphogluconolactonase activity
D9C14_RS15110	COG1834	amidinotransferase
D9C14_RS15115	COG1607	acyl-coa hydrolase
D9C14_RS15120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9C14_RS15120	COG1017	nitric oxide dioxygenase activity
D9C14_RS15130	COG2323	membrane
D9C14_RS15135	COG2318	DinB family
D9C14_RS15140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C14_RS15145	COG2076	Multidrug Resistance protein
D9C14_RS15150	COG2076	Multidrug Resistance protein
D9C14_RS15155	COG0788	formyltetrahydrofolate deformylase activity
D9C14_RS15160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9C14_RS15165	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D9C14_RS15170	COG1764	response to oxidative stress
D9C14_RS15175	COG1846	Transcriptional regulator
D9C14_RS15180	COG1764	response to oxidative stress
D9C14_RS15190	COG0590	tRNA wobble adenosine to inosine editing
D9C14_RS15195	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C14_RS15200	COG1404	Belongs to the peptidase S8 family
D9C14_RS15205	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C14_RS15210	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9C14_RS15215	COG1122	ATPase activity
D9C14_RS15220	COG4721	ABC-type cobalt transport system, permease component
D9C14_RS15230	COG0745	RESPONSE REGULATOR receiver
D9C14_RS15235	COG3850	Histidine kinase
D9C14_RS15235	COG5002	protein histidine kinase activity
D9C14_RS15240	COG3212	peptidase
D9C14_RS15245	COG3212	peptidase
D9C14_RS15260	COG2239	Acts as a magnesium transporter
D9C14_RS15265	COG0789	Transcriptional regulator
D9C14_RS15280	COG1846	Transcriptional regulator
D9C14_RS15285	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C14_RS15290	COG0726	polysaccharide deacetylase
D9C14_RS15295	COG1408	metallophosphoesterase
D9C14_RS15305	COG0463	Glycosyl transferase, family 2
D9C14_RS15310	COG3285	dna ligase
D9C14_RS15310	COG1793	dna ligase
D9C14_RS15315	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D9C14_RS15320	COG5001	Diguanylate cyclase
D9C14_RS15320	COG3300	MHYT domain
D9C14_RS15325	COG0586	Pfam SNARE associated Golgi protein
D9C14_RS15330	COG0861	Integral membrane protein TerC family
D9C14_RS15335	COG1191	sigma factor activity
D9C14_RS15355	COG0501	Belongs to the peptidase M48B family
D9C14_RS15360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9C14_RS15375	COG3594	Acyltransferase
D9C14_RS15380	COG5002	protein histidine kinase activity
D9C14_RS15385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9C14_RS15395	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D9C14_RS15400	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D9C14_RS15405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9C14_RS15410	COG0436	Aminotransferase
D9C14_RS15415	COG1850	ribulose-bisphosphate carboxylase activity
D9C14_RS15420	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
D9C14_RS15425	COG0235	Class ii aldolase
D9C14_RS15430	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D9C14_RS15435	COG3339	Conserved Protein
D9C14_RS15450	COG3852	Histidine kinase
D9C14_RS15460	COG1846	Transcriptional regulator
D9C14_RS15465	COG1360	Flagellar Motor Protein
D9C14_RS15470	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9C14_RS15475	COG0542	response to heat
D9C14_RS15480	COG3949	Membrane
D9C14_RS15485	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D9C14_RS15490	COG0720	synthase
D9C14_RS15495	COG0602	queuosine metabolic process
D9C14_RS15500	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D9C14_RS15505	COG1733	regulation of RNA biosynthetic process
D9C14_RS15510	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS15515	COG4641	Protein conserved in bacteria
D9C14_RS15515	COG1388	LysM domain
D9C14_RS15520	COG1388	LysM domain
D9C14_RS15525	COG3858	chitin binding
D9C14_RS15535	COG4873	Protein conserved in bacteria
D9C14_RS15550	COG3773	Cell wall hydrolase
D9C14_RS15555	COG2244	polysaccharide biosynthetic process
D9C14_RS15560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C14_RS15565	COG2217	Heavy metal translocating P-type atpase
D9C14_RS15575	COG0006	proline dipeptidase activity
D9C14_RS15580	COG1609	Transcriptional regulator
D9C14_RS15585	COG3711	transcriptional antiterminator
D9C14_RS15590	COG1263	PTS System
D9C14_RS15590	COG2190	(PTS) system
D9C14_RS15590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C14_RS15595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C14_RS15600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D9C14_RS15610	COG1533	DNA photolyase activity
D9C14_RS15615	COG0456	acetyltransferase
D9C14_RS15620	COG0840	transmembrane signaling receptor activity
D9C14_RS15625	COG2084	Dehydrogenase
D9C14_RS15630	COG2340	Cysteine-rich secretory protein family
D9C14_RS15635	COG0768	penicillin binding
D9C14_RS15640	COG4191	Histidine kinase
D9C14_RS15645	COG0436	Aminotransferase
D9C14_RS15655	COG0784	Response regulator, receiver
D9C14_RS15655	COG0835	chemotaxis
D9C14_RS15665	COG2814	Major facilitator Superfamily
D9C14_RS15670	COG1376	ErfK ybiS ycfS ynhG family protein
D9C14_RS15675	COG1408	metallophosphoesterase
D9C14_RS15680	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS15685	COG2200	EAL domain
D9C14_RS15690	COG4703	Protein of unknown function (DUF1797)
D9C14_RS15695	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D9C14_RS15705	COG0517	IMP dehydrogenase activity
D9C14_RS15710	COG0583	DNA-binding transcription factor activity
D9C14_RS15715	COG0716	FMN binding
D9C14_RS15725	COG0716	FMN binding
D9C14_RS15730	COG2171	N-acyltransferase activity
D9C14_RS15735	COG1473	amidohydrolase
D9C14_RS15745	COG0668	transmembrane transport
D9C14_RS15750	COG0450	alkyl hydroperoxide reductase
D9C14_RS15755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C14_RS15770	COG0746	molybdenum cofactor guanylyltransferase activity
D9C14_RS15775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C14_RS15780	COG0303	'Molybdopterin
D9C14_RS15785	COG1763	Mo-molybdopterin cofactor biosynthetic process
D9C14_RS15790	COG0314	molybdopterin synthase activity
D9C14_RS15795	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D9C14_RS15800	COG1132	(ABC) transporter
D9C14_RS15805	COG1132	(ABC) transporter
D9C14_RS15815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9C14_RS15820	COG1136	(ABC) transporter
D9C14_RS15825	COG0577	efflux transmembrane transporter activity
D9C14_RS15830	COG1349	DNA-binding transcription factor activity
D9C14_RS15835	COG1105	Belongs to the carbohydrate kinase PfkB family
D9C14_RS15840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C14_RS15840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C14_RS15840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C14_RS15845	COG0681	Belongs to the peptidase S26 family
D9C14_RS15855	COG0488	(ABC) transporter
D9C14_RS15860	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9C14_RS15865	COG2309	aminopeptidase activity
D9C14_RS15875	COG1077	Cell shape determining protein MreB Mrl
D9C14_RS15880	COG2002	toxin-antitoxin pair type II binding
D9C14_RS15885	COG3852	Histidine kinase
D9C14_RS15890	COG2105	PFAM AIG2 family protein
D9C14_RS15890	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D9C14_RS15895	COG0569	domain protein
D9C14_RS15900	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9C14_RS15905	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9C14_RS15910	COG5503	Protein of unknown function (DUF1447)
D9C14_RS15915	COG0561	phosphatase activity
D9C14_RS15920	COG0242	peptide deformylase activity
D9C14_RS15930	COG0497	DNA recombination
D9C14_RS15935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C14_RS15940	COG0022	dehydrogenase e1 component
D9C14_RS15945	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C14_RS15950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C14_RS15955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C14_RS15965	COG1982	Orn Lys Arg decarboxylase major
D9C14_RS15970	COG4476	Belongs to the UPF0223 family
D9C14_RS15975	COG4493	Belongs to the UPF0637 family
D9C14_RS15985	COG0483	inositol monophosphate 1-phosphatase activity
D9C14_RS15995	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D9C14_RS16015	COG1595	DNA-templated transcription, initiation
D9C14_RS16035	COG1217	gtp-binding protein TYPA
D9C14_RS16045	COG4896	Protein conserved in bacteria
D9C14_RS16055	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D9C14_RS16060	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9C14_RS16065	COG2066	Belongs to the glutaminase family
D9C14_RS16070	COG4838	Belongs to the UPF0358 family
D9C14_RS16075	COG0772	Belongs to the SEDS family
D9C14_RS16080	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D9C14_RS16085	COG1612	heme a metabolic process
D9C14_RS16090	COG0109	protoheme IX farnesyltransferase activity
D9C14_RS16095	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9C14_RS16095	COG2010	Cytochrome c
D9C14_RS16100	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9C14_RS16105	COG1845	cytochrome c oxidase, subunit III
D9C14_RS16110	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9C14_RS16115	COG3336	cytochrome c oxidase
D9C14_RS16125	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D9C14_RS16130	COG2340	Cysteine-rich secretory protein family
D9C14_RS16145	COG3679	Belongs to the UPF0342 family
D9C14_RS16150	COG4471	UPF0298 protein
D9C14_RS16155	COG0742	ribosomal rna small subunit methyltransferase
D9C14_RS16160	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D9C14_RS16165	COG3314	Sporulation integral membrane protein YlbJ
D9C14_RS16170	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9C14_RS16175	COG3480	Lon protease (S16) C-terminal proteolytic domain
D9C14_RS16180	COG1323	Belongs to the UPF0348 family
D9C14_RS16190	COG1399	metal-binding, possibly nucleic acid-binding protein
D9C14_RS16205	COG0454	-acetyltransferase
D9C14_RS16210	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9C14_RS16215	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D9C14_RS16220	COG2001	Belongs to the MraZ family
D9C14_RS16225	COG0275	rRNA processing
D9C14_RS16230	COG4839	cell division protein FtsL
D9C14_RS16235	COG0768	penicillin binding
D9C14_RS16240	COG0768	penicillin binding
D9C14_RS16245	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D9C14_RS16250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9C14_RS16255	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9C14_RS16260	COG0772	Belongs to the SEDS family
D9C14_RS16265	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C14_RS16270	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D9C14_RS16275	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D9C14_RS16280	COG3879	Bacterial protein of unknown function (DUF881)
D9C14_RS16285	COG3879	Bacterial protein of unknown function (DUF881)
D9C14_RS16290	COG3856	small basic protein
D9C14_RS16295	COG0849	cell division
D9C14_RS16300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9C14_RS16305	COG4412	M6 family metalloprotease domain protein
D9C14_RS16305	COG1404	Belongs to the peptidase S8 family
D9C14_RS16315	COG1191	sigma factor activity
D9C14_RS16320	COG1191	sigma factor activity
D9C14_RS16325	COG1119	ATPase activity
D9C14_RS16330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C14_RS16335	COG1873	PFAM PRC-barrel domain
D9C14_RS16340	COG1496	oxidoreductase activity
D9C14_RS16345	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D9C14_RS16350	COG1799	cell septum assembly
D9C14_RS16355	COG0762	integral membrane protein
D9C14_RS16360	COG2302	S4 RNA-binding domain
D9C14_RS16365	COG3599	regulation of cell shape
D9C14_RS16370	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D9C14_RS16375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C14_RS16380	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D9C14_RS16385	COG0564	pseudouridine synthase activity
D9C14_RS16390	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D9C14_RS16395	COG2233	PERMEase
D9C14_RS16400	COG0540	Belongs to the ATCase OTCase family
D9C14_RS16405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9C14_RS16410	COG0505	Belongs to the CarA family
D9C14_RS16415	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9C14_RS16420	COG0543	2 iron, 2 sulfur cluster binding
D9C14_RS16425	COG0167	dihydroorotate dehydrogenase activity
D9C14_RS16430	COG0284	orotidine-5'-phosphate decarboxylase activity
D9C14_RS16435	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D9C14_RS16440	COG0175	sulfate reduction
D9C14_RS16445	COG0306	phosphate transporter
D9C14_RS16450	COG2046	Belongs to the sulfate adenylyltransferase family
D9C14_RS16455	COG0529	Catalyzes the synthesis of activated sulfate
D9C14_RS16460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9C14_RS16465	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D9C14_RS16470	COG1648	precorrin-2 dehydrogenase activity
D9C14_RS16475	COG1293	RNA-binding protein homologous to eukaryotic snRNP
D9C14_RS16480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9C14_RS16485	COG1561	YicC-like family, N-terminal region
D9C14_RS16495	COG0194	GDP metabolic process
D9C14_RS16500	COG1758	RNA polymerase activity
D9C14_RS16505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9C14_RS16510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9C14_RS16515	COG0242	peptide deformylase activity
D9C14_RS16520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D9C14_RS16525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D9C14_RS16525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9C14_RS16530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D9C14_RS16535	COG0631	protein serine/threonine phosphatase activity
D9C14_RS16540	COG0515	serine threonine protein kinase
D9C14_RS16540	COG2815	serine threonine protein kinase
D9C14_RS16545	COG1162	GTPase activity
D9C14_RS16550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9C14_RS16555	COG1564	THIamine pyrophosphokinase
D9C14_RS16565	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D9C14_RS16570	COG1302	Protein conserved in bacteria
D9C14_RS16575	COG1461	Dihydroxyacetone kinase
D9C14_RS16580	COG1760	l-serine dehydratase
D9C14_RS16585	COG1760	l-serine dehydratase
D9C14_RS16590	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D9C14_RS16595	COG1349	DNA-binding transcription factor activity
D9C14_RS16595	COG2050	protein possibly involved in aromatic compounds catabolism
D9C14_RS16600	COG0416	fatty acid biosynthetic process
D9C14_RS16605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9C14_RS16610	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS16620	COG0571	ribonuclease III activity
D9C14_RS16625	COG1196	nuclear chromosome segregation
D9C14_RS16630	COG0552	protein localization to endoplasmic reticulum
D9C14_RS16640	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D9C14_RS16645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D9C14_RS16650	COG0228	four-way junction DNA binding
D9C14_RS16655	COG1837	Belongs to the UPF0109 family
D9C14_RS16665	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D9C14_RS16670	COG0336	Belongs to the RNA methyltransferase TrmD family
D9C14_RS16675	COG0335	large ribosomal subunit rRNA binding
D9C14_RS16680	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9C14_RS16685	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9C14_RS16695	COG2257	FlhB HrpN YscU SpaS Family
D9C14_RS16700	COG0045	succinate-CoA ligase (ADP-forming) activity
D9C14_RS16705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D9C14_RS16710	COG0758	DNA mediated transformation
D9C14_RS16715	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9C14_RS16720	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D9C14_RS16725	COG4974	Belongs to the 'phage' integrase family
D9C14_RS16730	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D9C14_RS16735	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D9C14_RS16740	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9C14_RS16745	COG1815	bacterial-type flagellum-dependent cell motility
D9C14_RS16750	COG1558	bacterial-type flagellum-dependent cell motility
D9C14_RS16755	COG1677	Flagellar hook-basal body complex protein FliE
D9C14_RS16760	COG1766	The M ring may be actively involved in energy transduction
D9C14_RS16765	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C14_RS16770	COG1317	bacterial-type flagellum organization
D9C14_RS16775	COG1157	protein secretion by the type III secretion system
D9C14_RS16780	COG2882	bacterial-type flagellum organization
D9C14_RS16785	COG3334	PFAM MgtE intracellular
D9C14_RS16790	COG3144	bacterial-type flagellum assembly
D9C14_RS16795	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D9C14_RS16800	COG4786	Flagellar basal body rod
D9C14_RS16805	COG1582	Flagellar protein (FlbD)
D9C14_RS16810	COG1580	Controls the rotational direction of flagella during chemotaxis
D9C14_RS16815	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C14_RS16820	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C14_RS16820	COG1776	CheC inhibitor of MCP methylation
D9C14_RS16825	COG2201	protein-glutamate methylesterase activity
D9C14_RS16830	COG3190	flagellar
D9C14_RS16835	COG1338	Plays a role in the flagellum-specific transport system
D9C14_RS16840	COG1987	bacterial-type flagellum assembly
D9C14_RS16845	COG1684	flagellar biosynthetic protein fliR
D9C14_RS16850	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9C14_RS16855	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9C14_RS16860	COG1419	protein localization to endoplasmic reticulum
D9C14_RS16865	COG0455	bacterial-type flagellum organization
D9C14_RS16870	COG2201	protein-glutamate methylesterase activity
D9C14_RS16875	COG2198	Histidine kinase
D9C14_RS16875	COG0643	Histidine kinase
D9C14_RS16880	COG0835	chemotaxis
D9C14_RS16885	COG1776	CheC inhibitor of MCP methylation
D9C14_RS16890	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D9C14_RS16895	COG1191	sigma factor activity
D9C14_RS16905	COG0052	Belongs to the universal ribosomal protein uS2 family
D9C14_RS16910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D9C14_RS16915	COG0528	UMP kinase activity
D9C14_RS16920	COG0233	cytoplasmic translational termination
D9C14_RS16925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9C14_RS16930	COG4589	Belongs to the CDS family
D9C14_RS16935	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D9C14_RS16940	COG0750	zinc metalloprotease
D9C14_RS16945	COG0442	prolyl-tRNA aminoacylation
D9C14_RS16950	COG2176	DNA-directed DNA polymerase activity
D9C14_RS16955	COG0779	Required for maturation of 30S ribosomal subunits
D9C14_RS16960	COG0195	Participates in both transcription termination and antitermination
D9C14_RS16965	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D9C14_RS16970	COG1358	cellular component organization or biogenesis
D9C14_RS16975	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D9C14_RS16980	COG1550	Protein conserved in bacteria
D9C14_RS16985	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D9C14_RS16990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D9C14_RS16995	COG0196	riboflavin kinase activity
D9C14_RS17000	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D9C14_RS17005	COG1185	polyribonucleotide nucleotidyltransferase activity
D9C14_RS17010	COG0726	polysaccharide deacetylase
D9C14_RS17015	COG0612	Peptidase, M16
D9C14_RS17020	COG1873	PFAM PRC-barrel domain
D9C14_RS17025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9C14_RS17030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9C14_RS17035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D9C14_RS17040	COG0527	aspartate kinase activity
D9C14_RS17045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9C14_RS17050	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9C14_RS17055	COG0740	serine-type endopeptidase activity
D9C14_RS17065	COG1674	ftsk spoiiie
D9C14_RS17065	COG4980	gas vesicle protein
D9C14_RS17070	COG2188	Transcriptional regulator
D9C14_RS17075	COG2814	Major facilitator Superfamily
D9C14_RS17080	COG0612	Peptidase, M16
D9C14_RS17085	COG0612	Peptidase, M16
D9C14_RS17090	COG0300	oxidoreductase activity
D9C14_RS17105	COG1426	Protein conserved in bacteria
D9C14_RS17110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D9C14_RS17115	COG1058	Belongs to the CinA family
D9C14_RS17115	COG1546	Belongs to the CinA family
D9C14_RS17120	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D9C14_RS17125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C14_RS17130	COG1418	mRNA catabolic process
D9C14_RS17135	COG1692	metallophosphoesterase
D9C14_RS17140	COG2359	stage V sporulation protein S
D9C14_RS17145	COG1063	alcohol dehydrogenase
D9C14_RS17150	COG0156	8-amino-7-oxononanoate synthase activity
D9C14_RS17160	COG4550	Control of competence regulator ComK, YlbF/YmcA
D9C14_RS17170	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D9C14_RS17175	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D9C14_RS17190	COG3226	Transcriptional regulator
D9C14_RS17195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C14_RS17205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9C14_RS17210	COG3321	synthase
D9C14_RS17215	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9C14_RS17215	COG2070	2-Nitropropane dioxygenase
D9C14_RS17220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C14_RS17225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9C14_RS17230	COG3425	synthase
D9C14_RS17235	COG1024	Enoyl-CoA hydratase
D9C14_RS17240	COG1024	Enoyl-CoA hydratase
D9C14_RS17245	COG0318	PFAM AMP-dependent synthetase and ligase
D9C14_RS17245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C14_RS17245	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS17245	COG3321	synthase
D9C14_RS17245	COG0300	oxidoreductase activity
D9C14_RS17250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C14_RS17250	COG0300	oxidoreductase activity
D9C14_RS17250	COG3321	synthase
D9C14_RS17250	COG4221	oxidoreductase activity
D9C14_RS17255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C14_RS17255	COG3321	synthase
D9C14_RS17255	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS17255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C14_RS17255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C14_RS17260	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS17260	COG4221	oxidoreductase activity
D9C14_RS17260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C14_RS17260	COG3321	synthase
D9C14_RS17265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C14_RS17265	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D9C14_RS17265	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D9C14_RS17265	COG3321	synthase
D9C14_RS17270	COG2124	cytochrome p450
D9C14_RS17280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C14_RS17285	COG1404	Belongs to the peptidase S8 family
D9C14_RS17295	COG4195	phage-related replication protein
D9C14_RS17300	COG1764	response to oxidative stress
D9C14_RS17305	COG2076	Multidrug Resistance protein
D9C14_RS17310	COG2076	Multidrug Resistance protein
D9C14_RS17325	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D9C14_RS17330	COG1923	regulation of RNA biosynthetic process
D9C14_RS17345	COG1780	Probably involved in ribonucleotide reductase function
D9C14_RS17350	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C14_RS17355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C14_RS17360	COG4112	unkown
D9C14_RS17365	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C14_RS17375	COG0464	growth
D9C14_RS17390	COG1525	nuclease
D9C14_RS17400	COG4282	regulation of fungal-type cell wall biogenesis
D9C14_RS17405	COG5444	nuclease activity
D9C14_RS17435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C14_RS17440	COG2211	Major facilitator Superfamily
D9C14_RS17445	COG2226	methyltransferase
D9C14_RS17450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C14_RS17460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C14_RS17465	COG0457	Tetratricopeptide repeat
D9C14_RS17480	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C14_RS17480	COG3409	Peptidoglycan-binding domain 1 protein
D9C14_RS17495	COG2433	Pfam Transposase IS66
D9C14_RS17505	COG0741	lytic transglycosylase activity
D9C14_RS17505	COG1196	nuclear chromosome segregation
D9C14_RS17505	COG0739	heme binding
D9C14_RS17530	COG0582	viral genome integration into host DNA
D9C14_RS17630	COG4373	Mu-like prophage FluMu protein gp28
D9C14_RS17670	COG0776	regulation of translation
D9C14_RS17735	COG3655	Transcriptional regulator
D9C14_RS17815	COG3655	Transcriptional regulator
D9C14_RS17870	COG3646	Phage regulatory protein
D9C14_RS17870	COG3645	SOS response
D9C14_RS17935	COG1793	dna ligase
D9C14_RS17940	COG2135	peptidase activity
D9C14_RS17955	COG4195	phage-related replication protein
D9C14_RS17960	COG3420	alginic acid biosynthetic process
D9C14_RS17960	COG5434	Belongs to the glycosyl hydrolase 28 family
D9C14_RS18020	COG3584	3D domain protein
D9C14_RS18035	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9C14_RS18145	COG1780	Probably involved in ribonucleotide reductase function
D9C14_RS18150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C14_RS18150	COG1372	Participates in initiation and elongation during chromosome replication
D9C14_RS18185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C14_RS18190	COG0756	dUTP diphosphatase activity
D9C14_RS18195	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D9C14_RS18255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D9C14_RS18305	COG3331	DNA recombination
D9C14_RS18320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D9C14_RS18325	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D9C14_RS18330	COG0789	Transcriptional regulator
D9C14_RS18335	COG0174	glutamine synthetase
D9C14_RS18375	COG1598	PFAM Uncharacterised protein family UPF0150
D9C14_RS18465	COG0463	Glycosyl transferase, family 2
D9C14_RS18485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C14_RS18500	COG3655	Transcriptional regulator
D9C14_RS18515	COG0135	phosphoribosylanthranilate isomerase activity
D9C14_RS18535	COG2211	Major facilitator Superfamily
D9C14_RS18540	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C14_RS18545	COG1940	carbohydrate kinase activity
D9C14_RS18550	COG2115	Belongs to the xylose isomerase family
D9C14_RS18555	COG1070	Carbohydrate kinase
D9C14_RS18565	COG1525	nuclease
D9C14_RS18570	COG2814	Major facilitator Superfamily
D9C14_RS18575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9C14_RS18585	COG0756	dUTP diphosphatase activity
D9C14_RS18620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C14_RS18630	COG3832	glyoxalase III activity
D9C14_RS18675	COG4195	phage-related replication protein
D9C14_RS18685	COG0346	lactoylglutathione lyase activity
D9C14_RS18695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D9C14_RS18700	COG1388	LysM domain
D9C14_RS18705	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9C14_RS18710	COG4224	UPF0291 protein
D9C14_RS18715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D9C14_RS18725	COG3763	UPF0154 protein
D9C14_RS18735	COG0785	Cytochrome C biogenesis protein
D9C14_RS18740	COG2201	protein-glutamate methylesterase activity
D9C14_RS18745	COG4846	Membrane protein involved in cytochrome C biogenesis
D9C14_RS18755	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C14_RS18770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D9C14_RS18775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C14_RS18795	COG0824	Thioesterase
D9C14_RS18805	COG4841	protein insertion into membrane
D9C14_RS18810	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D9C14_RS18815	COG1832	CoA-binding protein
D9C14_RS18820	COG0187	DNA topoisomerase II activity
D9C14_RS18825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9C14_RS18835	COG1115	amino acid carrier protein
D9C14_RS18840	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D9C14_RS18850	COG5520	Belongs to the glycosyl hydrolase 30 family
D9C14_RS18855	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C14_RS18865	COG2246	polysaccharide biosynthetic process
D9C14_RS18870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C14_RS18875	COG0586	Pfam SNARE associated Golgi protein
D9C14_RS18880	COG2404	hydrolase activity, acting on ester bonds
D9C14_RS18885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9C14_RS18890	COG1024	Enoyl-CoA hydratase
D9C14_RS18895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9C14_RS18900	COG0511	ligase activity, forming carbon-carbon bonds
D9C14_RS18905	COG0439	Biotin carboxylase
D9C14_RS18910	COG0318	PFAM AMP-dependent synthetase and ligase
D9C14_RS18915	COG1960	acyl-CoA dehydrogenase activity
D9C14_RS18930	COG1649	PFAM Uncharacterised BCR, COG1649
D9C14_RS18940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C14_RS18940	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D9C14_RS18945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C14_RS18950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C14_RS18955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C14_RS18960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C14_RS18965	COG2027	D-alanyl-D-alanine carboxypeptidase
D9C14_RS18970	COG2017	converts alpha-aldose to the beta-anomer
D9C14_RS18975	COG0534	Mate efflux family protein
D9C14_RS18990	COG0582	viral genome integration into host DNA
D9C14_RS18995	COG0166	Belongs to the GPI family
D9C14_RS19000	COG0405	Gamma-glutamyltransferase
D9C14_RS19005	COG0583	DNA-binding transcription factor activity
D9C14_RS19010	COG0604	alcohol dehydrogenase
D9C14_RS19015	COG0493	'glutamate synthase
D9C14_RS19020	COG0067	glutamate synthase
D9C14_RS19020	COG0070	glutamate synthase
D9C14_RS19020	COG0069	glutamate synthase activity
D9C14_RS19025	COG0583	DNA-binding transcription factor activity
D9C14_RS19030	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9C14_RS19035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C14_RS19045	COG0300	oxidoreductase activity
D9C14_RS19050	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9C14_RS19060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C14_RS19075	COG2814	Major facilitator Superfamily
D9C14_RS19080	COG1070	Carbohydrate kinase
D9C14_RS19085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9C14_RS19090	COG0243	molybdopterin cofactor binding
D9C14_RS19120	COG5278	phosphoserine phosphatase activity
D9C14_RS19120	COG0840	transmembrane signaling receptor activity
D9C14_RS19125	COG2368	4-hydroxyphenylacetate
D9C14_RS19130	COG4305	rare lipoprotein A
D9C14_RS19135	COG3619	membrane
D9C14_RS19140	COG3866	Pectate lyase
D9C14_RS19145	COG2135	peptidase activity
D9C14_RS19155	COG2140	Oxalate decarboxylase
D9C14_RS19165	COG0456	acetyltransferase
D9C14_RS19185	COG2720	vancomycin resistance protein
D9C14_RS19195	COG3655	Transcriptional regulator
D9C14_RS19200	COG3739	integral membrane protein
D9C14_RS19205	COG0583	DNA-binding transcription factor activity
D9C14_RS19210	COG0697	spore germination
D9C14_RS19220	COG0693	protein deglycase activity
D9C14_RS19225	COG2367	Beta-lactamase
D9C14_RS19250	COG3848	Pyruvate phosphate dikinase
D9C14_RS19250	COG0574	Belongs to the PEP-utilizing enzyme family
D9C14_RS19255	COG0726	polysaccharide deacetylase
D9C14_RS19265	COG2314	TM2 domain
D9C14_RS19270	COG1396	sequence-specific DNA binding
D9C14_RS19390	COG0457	Tetratricopeptide repeat
D9C14_RS19425	COG4282	regulation of fungal-type cell wall biogenesis
D9C14_RS19430	COG1231	oxidoreductase activity
D9C14_RS19435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C14_RS19440	COG0662	Cupin 2, conserved barrel domain protein
D9C14_RS19440	COG2207	Transcriptional regulator
D9C14_RS19445	COG0456	acetyltransferase
D9C14_RS19450	COG1309	transcriptional regulator
D9C14_RS19455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C14_RS19460	COG3708	Transcriptional regulator
D9C14_RS19465	COG2378	regulation of single-species biofilm formation
D9C14_RS19475	COG0640	Transcriptional regulator
D9C14_RS19480	COG0741	lytic transglycosylase activity
D9C14_RS19485	COG2322	membrane
D9C14_RS19500	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9C14_RS19505	COG3239	Fatty acid desaturase
D9C14_RS19510	COG4585	Histidine kinase
D9C14_RS19515	COG2197	response regulator
D9C14_RS19525	COG1388	LysM domain
D9C14_RS19525	COG3584	3D domain protein
D9C14_RS19530	COG0514	ATP-dependent DNA helicase (RecQ)
D9C14_RS19545	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9C14_RS19550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C14_RS19565	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C14_RS19590	COG1012	belongs to the aldehyde dehydrogenase family
D9C14_RS19595	COG1657	PFAM Prenyltransferase squalene oxidase
D9C14_RS19600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9C14_RS19605	COG0733	neurotransmitter:sodium symporter activity
D9C14_RS19610	COG0385	Bile acid
D9C14_RS19615	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C14_RS19620	COG0567	Dehydrogenase, E1 component
D9C14_RS19625	COG4548	von Willebrand factor, type A
D9C14_RS19630	COG0714	Associated with various cellular activities
D9C14_RS19635	COG2032	superoxide dismutase activity
D9C14_RS19640	COG0791	NLP P60 protein
D9C14_RS19640	COG1388	LysM domain
D9C14_RS19645	COG1819	glycosyl
D9C14_RS19650	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9C14_RS19655	COG0534	Mate efflux family protein
D9C14_RS19660	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C14_RS19665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C14_RS19670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C14_RS19680	COG2962	Rard protein
D9C14_RS19695	COG2610	gluconate transmembrane transporter activity
D9C14_RS19700	COG1942	4-Oxalocrotonate Tautomerase
D9C14_RS19705	COG1733	regulation of RNA biosynthetic process
D9C14_RS19710	COG0778	Nitroreductase
D9C14_RS19715	COG0400	carboxylic ester hydrolase activity
D9C14_RS19720	COG0346	lactoylglutathione lyase activity
D9C14_RS19730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C14_RS19735	COG3409	Peptidoglycan-binding domain 1 protein
D9C14_RS19735	COG0793	Belongs to the peptidase S41A family
D9C14_RS19740	COG2226	methyltransferase
D9C14_RS19750	COG1876	peptidase activity
D9C14_RS19755	COG0813	purine-nucleoside phosphorylase activity
D9C14_RS19770	COG0671	phosphoesterase, PA-phosphatase related
D9C14_RS19795	COG4479	Belongs to the UPF0346 family
D9C14_RS19805	COG1509	lysine 2,3-aminomutase activity
D9C14_RS19810	COG0456	acetyltransferase
D9C14_RS19815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C14_RS19820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9C14_RS19825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9C14_RS19830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C14_RS19845	COG0456	acetyltransferase
D9C14_RS19850	COG0463	Glycosyl transferase, family 2
D9C14_RS19865	COG4641	Protein conserved in bacteria
D9C14_RS19870	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
D9C14_RS19875	COG1086	Polysaccharide biosynthesis protein
D9C14_RS19880	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9C14_RS19885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9C14_RS19890	COG1846	Transcriptional regulator
D9C14_RS19895	COG0534	Mate efflux family protein
D9C14_RS19905	COG4698	Protein conserved in bacteria
D9C14_RS19910	COG2755	lipolytic protein G-D-S-L family
D9C14_RS19915	COG1999	signal sequence binding
D9C14_RS19925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9C14_RS19930	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9C14_RS19935	COG1272	protein, Hemolysin III
D9C14_RS19940	COG0204	Acyl-transferase
D9C14_RS19945	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C14_RS19950	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D9C14_RS19955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9C14_RS19965	COG2136	Putative SAM-dependent methyltransferase
D9C14_RS19965	COG2521	methyltransferase
D9C14_RS19975	COG0129	dihydroxy-acid dehydratase activity
D9C14_RS19980	COG1413	lyase activity
D9C14_RS19985	COG1418	mRNA catabolic process
D9C14_RS19990	COG0386	Belongs to the glutathione peroxidase family
D9C14_RS19995	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D9C14_RS20000	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C14_RS20010	COG1278	Cold shock
D9C14_RS20030	COG0328	RNA-DNA hybrid ribonuclease activity
D9C14_RS20035	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D9C14_RS20040	COG0328	RNA-DNA hybrid ribonuclease activity
D9C14_RS20050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C14_RS20065	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9C14_RS20075	COG1755	Isoprenylcysteine carboxyl methyltransferase
D9C14_RS20080	COG3424	synthase
D9C14_RS20085	COG2233	PERMEase
D9C14_RS20090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C14_RS20095	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D9C14_RS20105	COG0800	Aldolase
D9C14_RS20110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C14_RS20115	COG1609	Transcriptional regulator
D9C14_RS20120	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D9C14_RS20125	COG1028	Short-chain dehydrogenase reductase Sdr
D9C14_RS20130	COG1199	ATP-dependent helicase activity
D9C14_RS20145	COG0116	Belongs to the methyltransferase superfamily
D9C14_RS20160	COG4474	Belongs to the UPF0398 family
D9C14_RS20175	COG3359	exonuclease
D9C14_RS20180	COG1205	dead DEAH box helicase
D9C14_RS20180	COG1111	helicase
D9C14_RS20185	COG2190	(PTS) system
D9C14_RS20190	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C14_RS20225	COG3331	DNA recombination
D9C14_RS20230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C14_RS20230	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9C14_RS20240	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D9C14_RS20245	COG3935	DnaD domain protein
D9C14_RS20250	COG0017	Asparaginyl-tRNA synthetase
D9C14_RS20255	COG0436	Aminotransferase
D9C14_RS20260	COG5353	protein conserved in bacteria
D9C14_RS20270	COG1199	ATP-dependent helicase activity
D9C14_RS20270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9C14_RS20275	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D9C14_RS20280	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D9C14_RS20285	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D9C14_RS20290	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D9C14_RS20290	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D9C14_RS20295	COG0617	tRNA 3'-terminal CCA addition
D9C14_RS20300	COG0438	transferase activity, transferring glycosyl groups
D9C14_RS20305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C14_RS20310	COG1803	Methylglyoxal synthase
D9C14_RS20315	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D9C14_RS20320	COG1694	Mazg nucleotide pyrophosphohydrolase
D9C14_RS20325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C14_RS20335	COG4347	Protein of unknown function (DUF1405)
D9C14_RS20340	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9C14_RS20340	COG2010	Cytochrome c
D9C14_RS20345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9C14_RS20350	COG0723	plastoquinol--plastocyanin reductase activity
D9C14_RS20360	COG5582	Belongs to the UPF0302 family
D9C14_RS20365	COG0457	Tetratricopeptide repeat
D9C14_RS20370	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D9C14_RS20375	COG0287	Prephenate dehydrogenase
D9C14_RS20380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D9C14_RS20385	COG0159	tryptophan synthase activity
D9C14_RS20390	COG0133	tryptophan synthase activity
D9C14_RS20395	COG0135	phosphoribosylanthranilate isomerase activity
D9C14_RS20405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9C14_RS20410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9C14_RS20415	COG4401	Chorismate mutase type I
D9C14_RS20420	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D9C14_RS20425	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D9C14_RS20430	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9C14_RS20435	COG0105	UTP biosynthetic process
D9C14_RS20440	COG0142	geranyltranstransferase activity
D9C14_RS20445	COG2226	methyltransferase
D9C14_RS20450	COG0142	geranyltranstransferase activity
D9C14_RS20460	COG0302	gtp cyclohydrolase
D9C14_RS20465	COG0776	regulation of translation
D9C14_RS20470	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9C14_RS20485	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D9C14_RS20490	COG1160	GTP binding
D9C14_RS20515	COG1304	FMN binding
D9C14_RS20520	COG0539	negative regulation of cytoplasmic translation
D9C14_RS20525	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D9C14_RS20535	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D9C14_RS20540	COG2959	enzyme of heme biosynthesis
D9C14_RS20545	COG3409	Peptidoglycan-binding domain 1 protein
D9C14_RS20545	COG3773	Cell wall hydrolase
D9C14_RS20550	COG2339	peptidase activity
D9C14_RS20555	COG0492	ferredoxin-NADP+ reductase activity
D9C14_RS20560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C14_RS20565	COG4862	establishment of competence for transformation
D9C14_RS20570	COG1408	metallophosphoesterase
D9C14_RS20580	COG1388	LysM domain
D9C14_RS20585	COG1266	CAAX protease self-immunity
D9C14_RS20590	COG0514	ATP-dependent DNA helicase (RecQ)
D9C14_RS20595	COG4955	Helix-turn-helix domain
D9C14_RS20600	COG1141	Ferredoxin
D9C14_RS20605	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D9C14_RS20610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9C14_RS20615	COG0710	3-dehydroquinate dehydratase activity
D9C14_RS20625	COG1595	DNA-templated transcription, initiation
D9C14_RS20630	COG5002	protein histidine kinase activity
D9C14_RS20635	COG0745	RESPONSE REGULATOR receiver
D9C14_RS20640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9C14_RS20645	COG1333	cytochrome c biogenesis protein
D9C14_RS20650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C14_RS20655	COG1187	pseudouridine synthase activity
D9C14_RS20660	COG0700	Nucleoside recognition
D9C14_RS20665	COG2715	membrane protein required for spore maturation
D9C14_RS20670	COG1686	Belongs to the peptidase S11 family
D9C14_RS20680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D9C14_RS20685	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D9C14_RS20690	COG1547	Domain of unknown function (DUF309)
D9C14_RS20695	COG0456	acetyltransferase
D9C14_RS20700	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D9C14_RS20705	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9C14_RS20705	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9C14_RS20710	COG0307	riboflavin synthase, alpha
D9C14_RS20715	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9C14_RS20715	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9C14_RS20725	COG0681	Belongs to the peptidase S26 family
D9C14_RS20735	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
D9C14_RS20755	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9C14_RS20765	COG4086	secreted protein
D9C14_RS20770	COG0019	diaminopimelate decarboxylase activity
D9C14_RS20775	COG0697	spore germination
D9C14_RS20790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C14_RS20810	COG1191	sigma factor activity
D9C14_RS20815	COG2172	sigma factor antagonist activity
D9C14_RS20820	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C14_RS20825	COG1686	Belongs to the peptidase S11 family
D9C14_RS20830	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D9C14_RS20835	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D9C14_RS20840	COG4974	Belongs to the 'phage' integrase family
D9C14_RS20850	COG0735	belongs to the Fur family
D9C14_RS20855	COG1300	Membrane
D9C14_RS20865	COG0281	malic enzyme
D9C14_RS20870	COG1757	Na H antiporter
D9C14_RS20875	COG1027	Aspartate ammonia-lyase
D9C14_RS20880	COG0252	asparaginase activity
D9C14_RS20885	COG1396	sequence-specific DNA binding
D9C14_RS20890	COG1379	DNA repair
D9C14_RS20895	COG0494	nUDIX hydrolase
D9C14_RS20905	COG0667	Aldo Keto reductase
D9C14_RS20915	COG1073	alpha beta
D9C14_RS20925	COG4918	Iron-sulphur cluster biosynthesis
D9C14_RS20930	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9C14_RS20930	COG0456	acetyltransferase
D9C14_RS20935	COG2329	Antibiotic biosynthesis monooxygenase
D9C14_RS20940	COG0456	acetyltransferase
D9C14_RS20950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C14_RS20960	COG2211	Major facilitator Superfamily
D9C14_RS20965	COG0346	lactoylglutathione lyase activity
D9C14_RS20970	COG1072	(Pantothenic acid kinase))
D9C14_RS20975	COG3048	D-serine ammonia-lyase activity
D9C14_RS20980	COG0300	oxidoreductase activity
D9C14_RS20985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C14_RS20990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C14_RS20995	COG4187	Peptidase family M20/M25/M40
D9C14_RS21000	COG1902	pentaerythritol trinitrate reductase activity
D9C14_RS21005	COG0596	Alpha beta hydrolase
D9C14_RS21015	COG1234	tRNA 3'-trailer cleavage
D9C14_RS21020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D9C14_RS21025	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9C14_RS21030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C14_RS21040	COG0706	membrane insertase activity
D9C14_RS21045	COG3361	conserved protein (COG2071)
D9C14_RS21050	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9C14_RS21055	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9C14_RS21060	COG0346	lactoylglutathione lyase activity
D9C14_RS21065	COG1376	ErfK ybiS ycfS ynhG family protein
D9C14_RS21070	COG4129	membrane
D9C14_RS21075	COG1126	abc transporter atp-binding protein
D9C14_RS21080	COG0765	amino acid transport
D9C14_RS21085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C14_RS21095	COG1597	lipid kinase activity
D9C14_RS21100	COG2814	Major facilitator Superfamily
D9C14_RS21105	COG4978	Transcriptional regulator
D9C14_RS21105	COG0789	Transcriptional regulator
D9C14_RS21110	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C14_RS21115	COG0022	dehydrogenase e1 component
D9C14_RS21120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C14_RS21125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C14_RS21130	COG3426	butyrate kinase activity
D9C14_RS21135	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C14_RS21140	COG0280	phosphate acetyltransferase
D9C14_RS21145	COG3290	protein histidine kinase activity
D9C14_RS21145	COG3829	transcription factor binding
D9C14_RS21155	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D9C14_RS21160	COG2079	MmgE PrpD family protein
D9C14_RS21165	COG0372	Belongs to the citrate synthase family
D9C14_RS21170	COG1960	acyl-CoA dehydrogenase activity
D9C14_RS21175	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9C14_RS21180	COG0183	Belongs to the thiolase family
D9C14_RS21185	COG0584	glycerophosphoryl diester phosphodiesterase
D9C14_RS21190	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C14_RS21205	COG1902	pentaerythritol trinitrate reductase activity
D9C14_RS21210	COG0745	RESPONSE REGULATOR receiver
D9C14_RS21215	COG0750	zinc metalloprotease
D9C14_RS21220	COG0497	DNA recombination
D9C14_RS21225	COG1438	arginine binding
D9C14_RS21230	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D9C14_RS21235	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9C14_RS21240	COG0142	geranyltranstransferase activity
D9C14_RS21245	COG1722	exodeoxyribonuclease VII activity
D9C14_RS21250	COG1570	exodeoxyribonuclease VII activity
D9C14_RS21255	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D9C14_RS21260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9C14_RS21265	COG1302	Protein conserved in bacteria
D9C14_RS21270	COG0439	Biotin carboxylase
D9C14_RS21275	COG0511	ligase activity, forming carbon-carbon bonds
D9C14_RS21315	COG3854	ATPases associated with a variety of cellular activities
D9C14_RS21325	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D9C14_RS21330	COG0006	proline dipeptidase activity
D9C14_RS21335	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D9C14_RS21345	COG3872	metal-dependent enzyme
D9C14_RS21355	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9C14_RS21360	COG1321	iron dependent repressor
D9C14_RS21365	COG0095	Lipoate-protein ligase
D9C14_RS21370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C14_RS21375	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9C14_RS21380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9C14_RS21385	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D9C14_RS21390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9C14_RS21405	COG1396	sequence-specific DNA binding
D9C14_RS21415	COG0681	Belongs to the peptidase S26 family
D9C14_RS21440	COG4940	Competence protein ComGF
D9C14_RS21450	COG4970	Tfp pilus assembly protein FimT
D9C14_RS21455	COG4537	Required for transformation and DNA binding
D9C14_RS21460	COG1459	type II secretion system
D9C14_RS21465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D9C14_RS21470	COG0517	IMP dehydrogenase activity
D9C14_RS21475	COG0598	Magnesium transport protein CorA
D9C14_RS21480	COG1253	flavin adenine dinucleotide binding
D9C14_RS21485	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C14_RS21495	COG1393	Belongs to the ArsC family
D9C14_RS21505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C14_RS21515	COG0011	TIGRFAM Protein of
D9C14_RS21525	COG2866	Carboxypeptidase
D9C14_RS21530	COG1368	sulfuric ester hydrolase activity
D9C14_RS21535	COG1940	carbohydrate kinase activity
D9C14_RS21540	COG4483	Protein conserved in bacteria
D9C14_RS21545	COG0457	Tetratricopeptide repeat
D9C14_RS21545	COG0705	Rhomboid family
D9C14_RS21555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D9C14_RS21565	COG0438	transferase activity, transferring glycosyl groups
D9C14_RS21580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9C14_RS21585	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C14_RS21590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C14_RS21595	COG0581	inorganic phosphate transmembrane transporter activity
D9C14_RS21600	COG0573	inorganic phosphate transmembrane transporter activity
D9C14_RS21605	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D9C14_RS21610	COG0768	penicillin binding
D9C14_RS21615	COG0477	Major facilitator Superfamily
D9C14_RS21620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9C14_RS21625	COG2839	Protein conserved in bacteria
D9C14_RS21630	COG5521	maltodextrose utilization protein MalA
D9C14_RS21635	COG1388	LysM domain
D9C14_RS21640	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D9C14_RS21645	COG4709	membrane
D9C14_RS21650	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D9C14_RS21655	COG0735	belongs to the Fur family
D9C14_RS21660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C14_RS21670	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D9C14_RS21675	COG0513	Belongs to the DEAD box helicase family
D9C14_RS21685	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D9C14_RS21690	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D9C14_RS21695	COG2384	SAM-dependent methyltransferase
D9C14_RS21700	COG2010	Cytochrome c
D9C14_RS21710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9C14_RS21715	COG0358	DNA primase activity
D9C14_RS21720	COG1671	Belongs to the UPF0178 family
D9C14_RS21725	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D9C14_RS21730	COG0517	IMP dehydrogenase activity
D9C14_RS21735	COG0751	glycine-tRNA ligase activity
D9C14_RS21740	COG0752	glycyl-tRNA synthetase alpha subunit
D9C14_RS21745	COG1381	Involved in DNA repair and RecF pathway recombination
D9C14_RS21755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D9C14_RS21760	COG0295	cytidine deaminase activity
D9C14_RS21765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D9C14_RS21770	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D9C14_RS21775	COG1480	7TM receptor with intracellular HD hydrolase
D9C14_RS21780	COG1702	phosphate starvation-inducible protein PhoH
D9C14_RS21785	COG0561	phosphatase activity
D9C14_RS21800	COG4864	UPF0365 protein
D9C14_RS21805	COG1030	water channel activity
D9C14_RS21810	COG1610	YqeY-like protein
D9C14_RS21820	COG1283	sodium-dependent phosphate transmembrane transporter activity
D9C14_RS21825	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9C14_RS21830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D9C14_RS21835	COG2264	protein methyltransferase activity
D9C14_RS21840	COG0484	heat shock protein binding
D9C14_RS21845	COG0443	Heat shock 70 kDa protein
D9C14_RS21850	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D9C14_RS21855	COG1420	regulation of RNA biosynthetic process
D9C14_RS21860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9C14_RS21865	COG0481	GTPase activity
D9C14_RS21875	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C14_RS21880	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D9C14_RS21885	COG0268	Binds directly to 16S ribosomal RNA
D9C14_RS21890	COG1466	dna polymerase III delta subunit
D9C14_RS21905	COG0658	competence protein
D9C14_RS21905	COG2333	competence protein COMEC
D9C14_RS21910	COG2131	deaminase
D9C14_RS21915	COG1555	photosystem II stabilization
D9C14_RS21915	COG1596	polysaccharide export
D9C14_RS21920	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C14_RS21925	COG2226	methyltransferase
D9C14_RS21930	COG0799	negative regulation of ribosome biogenesis
D9C14_RS21935	COG1713	HD superfamily hydrolase involved in NAD metabolism
D9C14_RS21940	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D9C14_RS21945	COG1534	Rna-binding protein
D9C14_RS21950	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D9C14_RS21955	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9C14_RS21960	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D9C14_RS21970	COG2755	lipolytic protein G-D-S-L family
D9C14_RS21975	COG3409	Peptidoglycan-binding domain 1 protein
D9C14_RS21975	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C14_RS21980	COG0398	Pfam SNARE associated Golgi protein
D9C14_RS21995	COG3209	COG3209 Rhs family protein
D9C14_RS22020	COG3223	Belongs to the PsiE family
D9C14_RS22025	COG0642	Histidine kinase
D9C14_RS22025	COG5002	protein histidine kinase activity
D9C14_RS22030	COG0745	RESPONSE REGULATOR receiver
D9C14_RS22035	COG2311	Membrane
D9C14_RS22045	COG0454	-acetyltransferase
D9C14_RS22050	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9C14_RS22060	COG0730	response to heat
D9C14_RS22065	COG0425	Belongs to the sulfur carrier protein TusA family
D9C14_RS22070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C14_RS22070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C14_RS22080	COG0425	Belongs to the sulfur carrier protein TusA family
D9C14_RS22080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C14_RS22090	COG2210	Belongs to the sulfur carrier protein TusA family
D9C14_RS22095	COG1937	Protein conserved in bacteria
D9C14_RS22110	COG0662	Cupin 2, conserved barrel domain protein
D9C14_RS22130	COG4978	Transcriptional regulator
D9C14_RS22130	COG0789	Transcriptional regulator
D9C14_RS22135	COG2814	Major facilitator Superfamily
D9C14_RS22140	COG0456	acetyltransferase
D9C14_RS22145	COG1253	flavin adenine dinucleotide binding
D9C14_RS22155	COG0697	spore germination
D9C14_RS22160	COG0583	DNA-binding transcription factor activity
D9C14_RS22165	COG2072	flavoprotein involved in K transport