locus-tag	class	description
KMZ16_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KMZ16_RS00010	COG0592	DNA-directed DNA polymerase activity
KMZ16_RS00015	COG2501	S4 domain
KMZ16_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KMZ16_RS00030	COG0187	DNA topoisomerase II activity
KMZ16_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMZ16_RS00070	COG0516	GMP reductase activity
KMZ16_RS00070	COG0517	IMP dehydrogenase activity
KMZ16_RS00075	COG1686	Belongs to the peptidase S11 family
KMZ16_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KMZ16_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KMZ16_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KMZ16_RS00100	COG1428	Deoxynucleoside kinase
KMZ16_RS00105	COG1428	Deoxynucleoside kinase
KMZ16_RS00110	COG1388	LysM domain
KMZ16_RS00110	COG3858	chitin binding
KMZ16_RS00115	COG1335	isochorismatase
KMZ16_RS00120	COG0590	tRNA wobble adenosine to inosine editing
KMZ16_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KMZ16_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KMZ16_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KMZ16_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KMZ16_RS00190	COG3853	Toxic anion resistance protein (TelA)
KMZ16_RS00195	COG1982	Orn Lys Arg decarboxylase major
KMZ16_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KMZ16_RS00205	COG3870	Protein conserved in bacteria
KMZ16_RS00210	COG1728	Protein conserved in bacteria
KMZ16_RS00215	COG0470	DNA polymerase III
KMZ16_RS00220	COG1774	PSP1 C-terminal conserved region
KMZ16_RS00225	COG4467	Involved in initiation control of chromosome replication
KMZ16_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KMZ16_RS00235	COG2827	Endonuclease containing a URI domain
KMZ16_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KMZ16_RS00245	COG2002	toxin-antitoxin pair type II binding
KMZ16_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KMZ16_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KMZ16_RS00255	COG0084	hydrolase, TatD family'
KMZ16_RS00260	COG3583	domain protein
KMZ16_RS00260	COG3584	3D domain protein
KMZ16_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KMZ16_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KMZ16_RS00280	COG4466	Protein conserved in bacteria
KMZ16_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KMZ16_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KMZ16_RS00300	COG0251	oxidation-reduction process
KMZ16_RS00305	COG2088	sporulation resulting in formation of a cellular spore
KMZ16_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KMZ16_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KMZ16_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KMZ16_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
KMZ16_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KMZ16_RS00340	COG2002	toxin-antitoxin pair type II binding
KMZ16_RS00345	COG2244	polysaccharide biosynthetic process
KMZ16_RS00350	COG3956	TIGRFAM MazG family protein
KMZ16_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KMZ16_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KMZ16_RS00375	COG1098	S1 RNA binding domain
KMZ16_RS00390	COG2208	phosphoserine phosphatase activity
KMZ16_RS00395	COG2304	oxidoreductase activity
KMZ16_RS00400	COG0515	serine threonine protein kinase
KMZ16_RS00405	COG0037	tRNA processing
KMZ16_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KMZ16_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KMZ16_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KMZ16_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KMZ16_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KMZ16_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KMZ16_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KMZ16_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
KMZ16_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KMZ16_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KMZ16_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KMZ16_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KMZ16_RS00470	COG1396	sequence-specific DNA binding
KMZ16_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KMZ16_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KMZ16_RS00560	COG4463	regulation of RNA biosynthetic process
KMZ16_RS00565	COG3880	PFAM UvrB UvrC protein
KMZ16_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KMZ16_RS00575	COG0542	response to heat
KMZ16_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KMZ16_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KMZ16_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
KMZ16_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KMZ16_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KMZ16_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KMZ16_RS00610	COG1045	serine acetyltransferase
KMZ16_RS00615	COG0215	cysteine-tRNA ligase activity
KMZ16_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KMZ16_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KMZ16_RS00630	COG3688	RNA-binding protein containing a PIN domain
KMZ16_RS00635	COG1595	DNA-templated transcription, initiation
KMZ16_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KMZ16_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
KMZ16_RS00660	COG0081	regulation of translation
KMZ16_RS00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KMZ16_RS00675	COG2813	Specifically methylates the guanine in position
KMZ16_RS00680	COG0085	RNA polymerase activity
KMZ16_RS00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMZ16_RS00690	COG1358	cellular component organization or biogenesis
KMZ16_RS00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KMZ16_RS00700	COG0049	tRNA binding
KMZ16_RS00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KMZ16_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KMZ16_RS00715	COG0596	Alpha beta hydrolase
KMZ16_RS00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KMZ16_RS00730	COG0088	Forms part of the polypeptide exit tunnel
KMZ16_RS00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KMZ16_RS00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KMZ16_RS00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KMZ16_RS00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KMZ16_RS00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KMZ16_RS00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KMZ16_RS00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KMZ16_RS00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KMZ16_RS00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KMZ16_RS00825	COG0201	protein transport
KMZ16_RS00830	COG0563	adenylate kinase activity
KMZ16_RS00835	COG0024	Methionine aminopeptidase
KMZ16_RS00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
KMZ16_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KMZ16_RS00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KMZ16_RS00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KMZ16_RS00865	COG0202	RNA polymerase activity
KMZ16_RS00870	COG0203	ribosomal protein L17
KMZ16_RS00875	COG1122	ATPase activity
KMZ16_RS00880	COG1122	ATPase activity
KMZ16_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMZ16_RS00890	COG0101	tRNA pseudouridine synthase activity
KMZ16_RS00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KMZ16_RS00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KMZ16_RS00905	COG2226	methyltransferase
KMZ16_RS00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
KMZ16_RS00920	COG0489	protein tyrosine kinase activity
KMZ16_RS00930	COG2194	sulfuric ester hydrolase activity
KMZ16_RS00935	COG0726	polysaccharide deacetylase
KMZ16_RS01015	COG0659	secondary active sulfate transmembrane transporter activity
KMZ16_RS01020	COG0385	Bile acid
KMZ16_RS01025	COG2819	hydrolase of the alpha beta superfamily
KMZ16_RS01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMZ16_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMZ16_RS01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KMZ16_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KMZ16_RS01045	COG2207	Transcriptional regulator
KMZ16_RS01050	COG3876	Protein conserved in bacteria
KMZ16_RS01055	COG1472	Belongs to the glycosyl hydrolase 3 family
KMZ16_RS01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KMZ16_RS01065	COG1263	PTS System
KMZ16_RS01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KMZ16_RS01070	COG1737	Transcriptional regulator
KMZ16_RS01075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KMZ16_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KMZ16_RS01085	COG1683	Conserved Protein
KMZ16_RS01115	COG1595	DNA-templated transcription, initiation
KMZ16_RS01120	COG5662	AntiSigma factor
KMZ16_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KMZ16_RS01130	COG4856	YbbR-like protein
KMZ16_RS01135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KMZ16_RS01140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KMZ16_RS01150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KMZ16_RS01155	COG2169	Transcriptional regulator
KMZ16_RS01160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KMZ16_RS01165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KMZ16_RS01170	COG3002	Belongs to the UPF0753 family
KMZ16_RS01175	COG0288	reversible hydration of carbon dioxide
KMZ16_RS01185	COG5609	conserved protein (DUF2294)
KMZ16_RS01190	COG0640	Transcriptional regulator
KMZ16_RS01195	COG2814	Major facilitator Superfamily
KMZ16_RS01210	COG1404	Belongs to the peptidase S8 family
KMZ16_RS01230	COG1132	(ABC) transporter
KMZ16_RS01235	COG1132	(ABC) transporter
KMZ16_RS01240	COG0596	Alpha beta hydrolase
KMZ16_RS01245	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS01250	COG0642	Histidine kinase
KMZ16_RS01260	COG0515	serine threonine protein kinase
KMZ16_RS01275	COG1113	amino acid transport
KMZ16_RS01290	COG2602	Beta-lactamase
KMZ16_RS01295	COG2124	cytochrome p450
KMZ16_RS01305	COG0531	amino acid
KMZ16_RS01310	COG0584	glycerophosphoryl diester phosphodiesterase
KMZ16_RS01315	COG2271	Major facilitator Superfamily
KMZ16_RS01325	COG0456	acetyltransferase
KMZ16_RS01325	COG1846	Transcriptional regulator
KMZ16_RS01330	COG2271	Major facilitator Superfamily
KMZ16_RS01340	COG3409	Peptidoglycan-binding domain 1 protein
KMZ16_RS01345	COG0697	spore germination
KMZ16_RS01350	COG1917	Cupin 2, conserved barrel domain protein
KMZ16_RS01350	COG2207	Transcriptional regulator
KMZ16_RS01355	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KMZ16_RS01360	COG3591	Belongs to the peptidase S1B family
KMZ16_RS01370	COG0596	Alpha beta hydrolase
KMZ16_RS01375	COG1183	phosphatidylcholine synthase activity
KMZ16_RS01380	COG0586	Pfam SNARE associated Golgi protein
KMZ16_RS01385	COG0688	phosphatidylethanolamine metabolic process
KMZ16_RS01400	COG1054	Belongs to the UPF0176 family
KMZ16_RS01405	COG1301	dicarboxylic acid transport
KMZ16_RS01410	COG1263	PTS System
KMZ16_RS01410	COG2190	(PTS) system
KMZ16_RS01410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KMZ16_RS01415	COG0363	glucosamine-6-phosphate deaminase activity
KMZ16_RS01420	COG2188	Transcriptional regulator
KMZ16_RS01430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KMZ16_RS01435	COG0833	amino acid
KMZ16_RS01440	COG2040	homocysteine
KMZ16_RS01445	COG1115	amino acid carrier protein
KMZ16_RS01450	COG2066	Belongs to the glutaminase family
KMZ16_RS01455	COG4191	Histidine kinase
KMZ16_RS01460	COG0784	Response regulator, receiver
KMZ16_RS01465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KMZ16_RS01470	COG1012	belongs to the aldehyde dehydrogenase family
KMZ16_RS01475	COG2271	Major facilitator Superfamily
KMZ16_RS01480	COG4948	Mandelate Racemase Muconate Lactonizing
KMZ16_RS01485	COG2186	Transcriptional regulator
KMZ16_RS01490	COG2721	sulfolactate sulfo-lyase activity
KMZ16_RS01495	COG3173	Aminoglycoside phosphotransferase
KMZ16_RS01505	COG0697	spore germination
KMZ16_RS01510	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS01515	COG2205	protein histidine kinase activity
KMZ16_RS01520	COG1131	(ABC) transporter
KMZ16_RS01540	COG3773	Cell wall hydrolase
KMZ16_RS01545	COG2304	oxidoreductase activity
KMZ16_RS01555	COG3540	Alkaline phosphatase
KMZ16_RS01560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KMZ16_RS01565	COG0805	protein transport
KMZ16_RS01570	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KMZ16_RS01575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KMZ16_RS01580	COG0477	Major facilitator Superfamily
KMZ16_RS01585	COG1309	transcriptional regulator
KMZ16_RS01590	COG0252	asparaginase activity
KMZ16_RS01595	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KMZ16_RS01600	COG1714	RDD family
KMZ16_RS01605	COG3012	SEC-C Motif Domain Protein
KMZ16_RS01605	COG1405	negative regulation of cell septum assembly
KMZ16_RS01610	COG3290	protein histidine kinase activity
KMZ16_RS01615	COG3279	Response regulator of the LytR AlgR family
KMZ16_RS01620	COG4555	ABC transporter
KMZ16_RS01625	COG1668	transmembrane transport
KMZ16_RS01630	COG0667	Aldo Keto reductase
KMZ16_RS01645	COG1595	DNA-templated transcription, initiation
KMZ16_RS01650	COG1595	DNA-templated transcription, initiation
KMZ16_RS01655	COG1876	peptidase activity
KMZ16_RS01660	COG0457	Tetratricopeptide repeat
KMZ16_RS01665	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS01670	COG0366	Alpha amylase catalytic
KMZ16_RS01675	COG0803	Belongs to the bacterial solute-binding protein 9 family
KMZ16_RS01680	COG1121	(ABC) transporter
KMZ16_RS01685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KMZ16_RS01690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMZ16_RS01695	COG2310	stress, protein
KMZ16_RS01700	COG2310	stress, protein
KMZ16_RS01705	COG2310	stress, protein
KMZ16_RS01710	COG0861	Integral membrane protein TerC family
KMZ16_RS01720	COG3853	Toxic anion resistance protein (TelA)
KMZ16_RS01725	COG0477	Major facilitator Superfamily
KMZ16_RS01730	COG2814	Major facilitator Superfamily
KMZ16_RS01735	COG0640	Transcriptional regulator
KMZ16_RS01740	COG4175	Glycine betaine
KMZ16_RS01740	COG0517	IMP dehydrogenase activity
KMZ16_RS01745	COG4176	ABC-type proline glycine betaine transport system permease component
KMZ16_RS01750	COG2113	Glycine betaine
KMZ16_RS01755	COG1473	amidohydrolase
KMZ16_RS01760	COG1288	antiporter activity
KMZ16_RS01770	COG0366	Alpha amylase catalytic
KMZ16_RS01775	COG0039	L-malate dehydrogenase activity
KMZ16_RS01780	COG1620	l-lactate permease
KMZ16_RS01785	COG2814	Major facilitator Superfamily
KMZ16_RS01790	COG1846	Transcriptional regulator
KMZ16_RS01795	COG1280	lysine exporter protein (LysE YggA)
KMZ16_RS01800	COG3403	YqcI/YcgG family
KMZ16_RS01805	COG1113	amino acid transport
KMZ16_RS01810	COG3665	Urea carboxylase-associated protein
KMZ16_RS01815	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KMZ16_RS01820	COG1660	Displays ATPase and GTPase activities
KMZ16_RS01825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KMZ16_RS01830	COG2226	methyltransferase
KMZ16_RS01835	COG0583	DNA-binding transcription factor activity
KMZ16_RS01840	COG3458	cephalosporin-C deacetylase activity
KMZ16_RS01845	COG3541	Predicted nucleotidyltransferase
KMZ16_RS01850	COG0506	proline dehydrogenase activity
KMZ16_RS01855	COG1012	belongs to the aldehyde dehydrogenase family
KMZ16_RS01860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMZ16_RS01865	COG2508	Transcriptional regulator
KMZ16_RS01870	COG3689	TIGRFAM TIGR03943 family protein
KMZ16_RS01875	COG0701	Predicted permease
KMZ16_RS01880	COG2267	carboxylic ester hydrolase activity
KMZ16_RS01885	COG0492	ferredoxin-NADP+ reductase activity
KMZ16_RS01890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KMZ16_RS01890	COG1587	Uroporphyrinogen-III synthase
KMZ16_RS01895	COG2146	nitrite reductase [NAD(P)H] activity
KMZ16_RS01900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KMZ16_RS01905	COG0243	molybdopterin cofactor binding
KMZ16_RS01910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KMZ16_RS01915	COG2223	nitrite transmembrane transporter activity
KMZ16_RS01920	COG1469	GTP cyclohydrolase I activity
KMZ16_RS01925	COG1376	ErfK ybiS ycfS ynhG family protein
KMZ16_RS01935	COG0523	cobalamin synthesis protein
KMZ16_RS01940	COG0765	amino acid transport
KMZ16_RS01945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KMZ16_RS01955	COG1714	RDD family
KMZ16_RS01965	COG2723	6-phospho-beta-galactosidase activity
KMZ16_RS01975	COG3209	COG3209 Rhs family protein
KMZ16_RS01980	COG0840	transmembrane signaling receptor activity
KMZ16_RS01980	COG3290	protein histidine kinase activity
KMZ16_RS01985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KMZ16_RS01990	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KMZ16_RS01995	COG1733	regulation of RNA biosynthetic process
KMZ16_RS02000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KMZ16_RS02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KMZ16_RS02025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KMZ16_RS02030	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KMZ16_RS02035	COG2814	Major facilitator Superfamily
KMZ16_RS02045	COG0697	spore germination
KMZ16_RS02060	COG2364	Membrane
KMZ16_RS02065	COG1126	abc transporter atp-binding protein
KMZ16_RS02070	COG0765	amino acid transport
KMZ16_RS02075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KMZ16_RS02080	COG0583	DNA-binding transcription factor activity
KMZ16_RS02085	COG0163	prenyltransferase activity
KMZ16_RS02090	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KMZ16_RS02105	COG0596	Alpha beta hydrolase
KMZ16_RS02110	COG3104	oligopeptide transport
KMZ16_RS02115	COG5434	Belongs to the glycosyl hydrolase 28 family
KMZ16_RS02125	COG0697	spore germination
KMZ16_RS02135	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KMZ16_RS02140	COG1136	(ABC) transporter
KMZ16_RS02145	COG0577	efflux transmembrane transporter activity
KMZ16_RS02150	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS02155	COG3850	Histidine kinase
KMZ16_RS02155	COG5002	protein histidine kinase activity
KMZ16_RS02160	COG0457	Tetratricopeptide repeat
KMZ16_RS02180	COG0527	aspartate kinase activity
KMZ16_RS02185	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMZ16_RS02190	COG4605	iron ion homeostasis
KMZ16_RS02195	COG4604	ABC transporter, ATP-binding protein
KMZ16_RS02200	COG4607	ABC-type enterochelin transport system periplasmic component
KMZ16_RS02205	COG2814	Major facilitator Superfamily
KMZ16_RS02210	COG1309	transcriptional regulator
KMZ16_RS02215	COG0778	Nitroreductase
KMZ16_RS02220	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KMZ16_RS02225	COG0640	Transcriptional regulator
KMZ16_RS02230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KMZ16_RS02235	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMZ16_RS02240	COG1012	belongs to the aldehyde dehydrogenase family
KMZ16_RS02245	COG4975	Glucose uptake
KMZ16_RS02250	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS02255	COG4549	nuclear export factor GLE1
KMZ16_RS02260	COG2372	response to copper ion
KMZ16_RS02260	COG1276	copper resistance
KMZ16_RS02265	COG1349	DNA-binding transcription factor activity
KMZ16_RS02275	COG2213	PTS system mannitol-specific
KMZ16_RS02280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KMZ16_RS02285	COG0246	Mannitol dehydrogenase
KMZ16_RS02290	COG0473	3-isopropylmalate dehydrogenase activity
KMZ16_RS02295	COG0681	Belongs to the peptidase S26 family
KMZ16_RS02300	COG0412	Dienelactone hydrolase
KMZ16_RS02305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KMZ16_RS02315	COG0561	phosphatase activity
KMZ16_RS02320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KMZ16_RS02325	COG1914	H( )-stimulated, divalent metal cation uptake system
KMZ16_RS02330	COG4336	lyase activity
KMZ16_RS02335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KMZ16_RS02340	COG1984	allophanate hydrolase subunit 2
KMZ16_RS02345	COG1414	Transcriptional regulator
KMZ16_RS02350	COG2755	lipolytic protein G-D-S-L family
KMZ16_RS02360	COG2329	Antibiotic biosynthesis monooxygenase
KMZ16_RS02365	COG0768	penicillin binding
KMZ16_RS02370	COG4989	oxidoreductase activity
KMZ16_RS02375	COG3711	transcriptional antiterminator
KMZ16_RS02380	COG0318	PFAM AMP-dependent synthetase and ligase
KMZ16_RS02385	COG2226	methyltransferase
KMZ16_RS02390	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS02395	COG1917	Cupin 2, conserved barrel domain protein
KMZ16_RS02400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KMZ16_RS02405	COG3871	stress protein (general stress protein 26)
KMZ16_RS02415	COG2814	Major facilitator Superfamily
KMZ16_RS02420	COG1522	sequence-specific DNA binding
KMZ16_RS02425	COG0551	DNA topoisomerase type I activity
KMZ16_RS02425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KMZ16_RS02430	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KMZ16_RS02435	COG3706	GGDEF domain
KMZ16_RS02440	COG5298	Protein conserved in bacteria
KMZ16_RS02445	COG1215	transferase activity, transferring glycosyl groups
KMZ16_RS02455	COG0531	amino acid
KMZ16_RS02460	COG0494	nUDIX hydrolase
KMZ16_RS02465	COG0028	Belongs to the TPP enzyme family
KMZ16_RS02480	COG1914	H( )-stimulated, divalent metal cation uptake system
KMZ16_RS02485	COG2261	transglycosylase associated protein
KMZ16_RS02490	COG4876	unkown
KMZ16_RS02495	COG2217	Heavy metal translocating P-type atpase
KMZ16_RS02500	COG3729	General stress protein
KMZ16_RS02505	COG0662	Cupin 2, conserved barrel domain protein
KMZ16_RS02510	COG2329	Antibiotic biosynthesis monooxygenase
KMZ16_RS02515	COG3546	catalase activity
KMZ16_RS02520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KMZ16_RS02525	COG3290	protein histidine kinase activity
KMZ16_RS02530	COG4565	transcriptional regulatory protein
KMZ16_RS02535	COG1301	dicarboxylic acid transport
KMZ16_RS02540	COG0628	permease
KMZ16_RS02545	COG1131	(ABC) transporter
KMZ16_RS02550	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KMZ16_RS02560	COG1960	acyl-CoA dehydrogenase activity
KMZ16_RS02575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMZ16_RS02580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KMZ16_RS02585	COG1181	Belongs to the D-alanine--D-alanine ligase family
KMZ16_RS02590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KMZ16_RS02595	COG0513	Belongs to the DEAD box helicase family
KMZ16_RS02600	COG3402	PFAM membrane-flanked domain
KMZ16_RS02605	COG3428	Bacterial PH domain
KMZ16_RS02610	COG0705	Rhomboid family
KMZ16_RS02615	COG0736	holo-[acyl-carrier-protein] synthase activity
KMZ16_RS02620	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KMZ16_RS02625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KMZ16_RS02630	COG0864	Transcriptional regulator
KMZ16_RS02635	COG2337	Toxic component of a toxin-antitoxin (TA) module
KMZ16_RS02640	COG1366	Belongs to the anti-sigma-factor antagonist family
KMZ16_RS02645	COG1366	Belongs to the anti-sigma-factor antagonist family
KMZ16_RS02650	COG2172	sigma factor antagonist activity
KMZ16_RS02655	COG2208	phosphoserine phosphatase activity
KMZ16_RS02660	COG1366	Belongs to the anti-sigma-factor antagonist family
KMZ16_RS02665	COG2172	sigma factor antagonist activity
KMZ16_RS02670	COG1191	sigma factor activity
KMZ16_RS02675	COG2208	phosphoserine phosphatase activity
KMZ16_RS02695	COG1673	EVE domain
KMZ16_RS02700	COG1846	Transcriptional regulator
KMZ16_RS02705	COG2183	response to ionizing radiation
KMZ16_RS02715	COG3091	SprT-like family
KMZ16_RS02755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KMZ16_RS02800	COG1476	TRANSCRIPTIONal
KMZ16_RS02825	COG0693	protein deglycase activity
KMZ16_RS02830	COG1278	Cold shock
KMZ16_RS02835	COG1329	Transcriptional regulator
KMZ16_RS02840	COG0697	spore germination
KMZ16_RS02845	COG1917	Cupin 2, conserved barrel domain protein
KMZ16_RS02845	COG2207	Transcriptional regulator
KMZ16_RS02850	COG0697	spore germination
KMZ16_RS02855	COG2207	Transcriptional regulator
KMZ16_RS02855	COG3708	Transcriptional regulator
KMZ16_RS02860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KMZ16_RS02865	COG0477	Major facilitator Superfamily
KMZ16_RS02875	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
KMZ16_RS02905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KMZ16_RS02910	COG1309	transcriptional regulator
KMZ16_RS02920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KMZ16_RS02925	COG2030	dehydratase
KMZ16_RS02930	COG3545	Serine hydrolase
KMZ16_RS02935	COG1733	regulation of RNA biosynthetic process
KMZ16_RS02940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMZ16_RS02945	COG1733	regulation of RNA biosynthetic process
KMZ16_RS02950	COG2249	NAD(P)H dehydrogenase (quinone) activity
KMZ16_RS02955	COG2814	Major facilitator Superfamily
KMZ16_RS02960	COG1309	transcriptional regulator
KMZ16_RS02965	COG0640	Transcriptional regulator
KMZ16_RS02970	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KMZ16_RS02980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KMZ16_RS02985	COG0697	spore germination
KMZ16_RS02990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KMZ16_RS02995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KMZ16_RS03000	COG0640	Transcriptional regulator
KMZ16_RS03005	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KMZ16_RS03020	COG4585	Histidine kinase
KMZ16_RS03025	COG2197	response regulator
KMZ16_RS03030	COG2409	Drug exporters of the RND superfamily
KMZ16_RS03035	COG0596	Alpha beta hydrolase
KMZ16_RS03040	COG1811	Na channel or pump
KMZ16_RS03045	COG4978	Transcriptional regulator
KMZ16_RS03045	COG0789	Transcriptional regulator
KMZ16_RS03050	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMZ16_RS03055	COG0778	Nitroreductase
KMZ16_RS03060	COG0346	lactoylglutathione lyase activity
KMZ16_RS03065	COG2259	Doxx family
KMZ16_RS03070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KMZ16_RS03090	COG2323	membrane
KMZ16_RS03095	COG2323	membrane
KMZ16_RS03100	COG0071	Belongs to the small heat shock protein (HSP20) family
KMZ16_RS03115	COG1309	transcriptional regulator
KMZ16_RS03130	COG0488	(ABC) transporter
KMZ16_RS03135	COG1113	amino acid transport
KMZ16_RS03140	COG2318	DinB family
KMZ16_RS03145	COG1846	Transcriptional regulator
KMZ16_RS03150	COG2409	Drug exporters of the RND superfamily
KMZ16_RS03150	COG1033	growth of symbiont in host cell
KMZ16_RS03155	COG0778	Nitroreductase
KMZ16_RS03160	COG1846	Transcriptional regulator
KMZ16_RS03165	COG2814	Major facilitator Superfamily
KMZ16_RS03170	COG0730	response to heat
KMZ16_RS03175	COG1802	Transcriptional regulator
KMZ16_RS03180	COG3858	chitin binding
KMZ16_RS03180	COG1388	LysM domain
KMZ16_RS03185	COG1819	glycosyl
KMZ16_RS03195	COG1785	Belongs to the alkaline phosphatase family
KMZ16_RS03200	COG5646	InterPro IPR014922
KMZ16_RS03210	COG0454	-acetyltransferase
KMZ16_RS03215	COG1078	dGTPase activity
KMZ16_RS03220	COG1388	LysM domain
KMZ16_RS03225	COG2814	Major facilitator Superfamily
KMZ16_RS03230	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KMZ16_RS03235	COG1447	Phosphotransferase system cellobiose-specific component IIA
KMZ16_RS03240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KMZ16_RS03245	COG2723	6-phospho-beta-galactosidase activity
KMZ16_RS03250	COG2188	Transcriptional regulator
KMZ16_RS03255	COG1940	carbohydrate kinase activity
KMZ16_RS03260	COG1482	cell wall glycoprotein biosynthetic process
KMZ16_RS03265	COG4124	Belongs to the glycosyl hydrolase 26 family
KMZ16_RS03310	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KMZ16_RS03315	COG0802	atpase or kinase
KMZ16_RS03320	COG1214	PFAM Peptidase M22, glycoprotease
KMZ16_RS03325	COG0456	acetyltransferase
KMZ16_RS03330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KMZ16_RS03335	COG0488	(ABC) transporter
KMZ16_RS03340	COG0315	cyclic pyranopterin monophosphate synthase activity
KMZ16_RS03345	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KMZ16_RS03350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KMZ16_RS03355	COG0805	protein transport
KMZ16_RS03365	COG1266	CAAX protease self-immunity
KMZ16_RS03375	COG0459	protein refolding
KMZ16_RS03385	COG5444	nuclease activity
KMZ16_RS03395	COG2322	membrane
KMZ16_RS03410	COG0457	Tetratricopeptide repeat
KMZ16_RS03415	COG1063	alcohol dehydrogenase
KMZ16_RS03420	COG2211	Major facilitator Superfamily
KMZ16_RS03425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KMZ16_RS03430	COG1842	Phage shock protein A
KMZ16_RS03435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KMZ16_RS03440	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KMZ16_RS03445	COG4260	virion core protein, lumpy skin disease virus
KMZ16_RS03455	COG2814	Major facilitator Superfamily
KMZ16_RS03460	COG1063	alcohol dehydrogenase
KMZ16_RS03465	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KMZ16_RS03470	COG0823	Involved in the tonB-independent uptake of proteins
KMZ16_RS03485	COG2267	carboxylic ester hydrolase activity
KMZ16_RS03495	COG2132	Multicopper oxidase
KMZ16_RS03500	COG1113	amino acid transport
KMZ16_RS03510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMZ16_RS03515	COG0714	Associated with various cellular activities
KMZ16_RS03520	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KMZ16_RS03525	COG1305	Transglutaminase-like
KMZ16_RS03530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KMZ16_RS03530	COG0519	Catalyzes the synthesis of GMP from XMP
KMZ16_RS03535	COG2252	PERMEase
KMZ16_RS03540	COG3064	Membrane
KMZ16_RS03550	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
KMZ16_RS03560	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KMZ16_RS03565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KMZ16_RS03570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KMZ16_RS03575	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KMZ16_RS03580	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMZ16_RS03585	COG0047	phosphoribosylformylglycinamidine synthase activity
KMZ16_RS03590	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMZ16_RS03595	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KMZ16_RS03600	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KMZ16_RS03605	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KMZ16_RS03610	COG0138	bifunctional purine biosynthesis protein purh
KMZ16_RS03615	COG0151	Belongs to the GarS family
KMZ16_RS03620	COG1522	sequence-specific DNA binding
KMZ16_RS03625	COG0531	amino acid
KMZ16_RS03635	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KMZ16_RS03640	COG1470	cell adhesion involved in biofilm formation
KMZ16_RS03645	COG4496	protein, YerC YecD
KMZ16_RS03650	COG0069	glutamate synthase activity
KMZ16_RS03655	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KMZ16_RS03660	COG0210	DNA helicase
KMZ16_RS03665	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KMZ16_RS03670	COG4851	CamS sex pheromone cAM373 precursor
KMZ16_RS03675	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KMZ16_RS03680	COG1285	pathogenesis
KMZ16_RS03685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMZ16_RS03690	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KMZ16_RS03695	COG0154	amidase activity
KMZ16_RS03700	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KMZ16_RS03710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KMZ16_RS03715	COG1597	lipid kinase activity
KMZ16_RS03720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KMZ16_RS03740	COG0457	Tetratricopeptide repeat
KMZ16_RS03765	COG5444	nuclease activity
KMZ16_RS03770	COG3391	amine dehydrogenase activity
KMZ16_RS03775	COG0457	Tetratricopeptide repeat
KMZ16_RS03785	COG0217	transcriptional regulatory protein
KMZ16_RS03795	COG1309	transcriptional regulator
KMZ16_RS03800	COG3631	Ketosteroid isomerase-related protein
KMZ16_RS03820	COG3546	catalase activity
KMZ16_RS03825	COG0454	-acetyltransferase
KMZ16_RS03835	COG5578	integral membrane protein
KMZ16_RS03840	COG2972	Histidine kinase
KMZ16_RS03845	COG4753	response regulator
KMZ16_RS03845	COG2207	Transcriptional regulator
KMZ16_RS03850	COG1653	transport
KMZ16_RS03855	COG1175	transmembrane transport
KMZ16_RS03860	COG0395	ABC-type sugar transport system, permease component
KMZ16_RS03865	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KMZ16_RS03870	COG2207	Transcriptional regulator
KMZ16_RS03875	COG2755	lipolytic protein G-D-S-L family
KMZ16_RS03885	COG5578	integral membrane protein
KMZ16_RS03890	COG3401	FG-GAP repeat protein
KMZ16_RS03895	COG3401	FG-GAP repeat protein
KMZ16_RS03900	COG2755	lipolytic protein G-D-S-L family
KMZ16_RS03905	COG1874	Beta-galactosidase
KMZ16_RS03915	COG1653	transport
KMZ16_RS03920	COG4209	transmembrane transport
KMZ16_RS03925	COG0395	ABC-type sugar transport system, permease component
KMZ16_RS03930	COG1486	melibiose metabolic process
KMZ16_RS03935	COG2323	membrane
KMZ16_RS03940	COG2329	Antibiotic biosynthesis monooxygenase
KMZ16_RS03945	COG0346	lactoylglutathione lyase activity
KMZ16_RS03960	COG5583	Uncharacterized small protein (DUF2292)
KMZ16_RS03965	COG0670	Belongs to the BI1 family
KMZ16_RS03970	COG0697	spore germination
KMZ16_RS03975	COG1846	Transcriptional regulator
KMZ16_RS03980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KMZ16_RS03995	COG2124	cytochrome p450
KMZ16_RS03995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KMZ16_RS04000	COG1368	sulfuric ester hydrolase activity
KMZ16_RS04005	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KMZ16_RS04010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KMZ16_RS04020	COG1216	Glycosyl transferase, family 2
KMZ16_RS04025	COG1442	glycosyl transferase family 8
KMZ16_RS04030	COG2223	nitrite transmembrane transporter activity
KMZ16_RS04035	COG1011	Hydrolase
KMZ16_RS04040	COG0531	amino acid
KMZ16_RS04045	COG1012	belongs to the aldehyde dehydrogenase family
KMZ16_RS04050	COG0840	transmembrane signaling receptor activity
KMZ16_RS04055	COG0488	(ABC) transporter
KMZ16_RS04065	COG0789	Transcriptional regulator
KMZ16_RS04070	COG2814	Major facilitator Superfamily
KMZ16_RS04080	COG0488	(ABC) transporter
KMZ16_RS04085	COG0513	Belongs to the DEAD box helicase family
KMZ16_RS04090	COG0456	acetyltransferase
KMZ16_RS04095	COG2130	NADP-dependent
KMZ16_RS04100	COG2211	Major facilitator Superfamily
KMZ16_RS04105	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KMZ16_RS04110	COG1120	ATPase activity
KMZ16_RS04115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMZ16_RS04120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMZ16_RS04125	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KMZ16_RS04140	COG3866	Pectate lyase
KMZ16_RS04145	COG0471	metal ion transport
KMZ16_RS04150	COG3290	protein histidine kinase activity
KMZ16_RS04155	COG4565	transcriptional regulatory protein
KMZ16_RS04160	COG3181	Tripartite tricarboxylate transporter family receptor
KMZ16_RS04170	COG2851	Citrate transporter
KMZ16_RS04175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KMZ16_RS04180	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KMZ16_RS04185	COG1254	Belongs to the acylphosphatase family
KMZ16_RS04190	COG2258	MOSC domain
KMZ16_RS04210	COG0024	Methionine aminopeptidase
KMZ16_RS04215	COG1263	PTS System
KMZ16_RS04215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KMZ16_RS04220	COG1368	sulfuric ester hydrolase activity
KMZ16_RS04235	COG1115	amino acid carrier protein
KMZ16_RS04240	COG0531	amino acid
KMZ16_RS04255	COG0697	spore germination
KMZ16_RS04260	COG1263	PTS System
KMZ16_RS04260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KMZ16_RS04265	COG0366	Alpha amylase catalytic
KMZ16_RS04270	COG2188	Transcriptional regulator
KMZ16_RS04275	COG0778	Nitroreductase
KMZ16_RS04280	COG0737	Belongs to the 5'-nucleotidase family
KMZ16_RS04285	COG0693	protein deglycase activity
KMZ16_RS04290	COG2814	Major facilitator Superfamily
KMZ16_RS04295	COG4840	Belongs to the UPF0435 family
KMZ16_RS04300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KMZ16_RS04305	COG4980	gas vesicle protein
KMZ16_RS04310	COG1295	ribonuclease BN
KMZ16_RS04315	COG0477	Major facilitator Superfamily
KMZ16_RS04320	COG0387	Pfam Sodium calcium exchanger
KMZ16_RS04330	COG0668	transmembrane transport
KMZ16_RS04335	COG0535	radical SAM domain protein
KMZ16_RS04345	COG0726	polysaccharide deacetylase
KMZ16_RS04350	COG2084	Dehydrogenase
KMZ16_RS04355	COG0598	Magnesium transport protein CorA
KMZ16_RS04360	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KMZ16_RS04365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KMZ16_RS04375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KMZ16_RS04380	COG4637	Psort location Cytoplasmic, score
KMZ16_RS04390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KMZ16_RS04395	COG0022	dehydrogenase e1 component
KMZ16_RS04400	COG0508	dehydrogenase complex catalyzes the overall conversion of
KMZ16_RS04405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KMZ16_RS04410	COG3284	Transcriptional regulator
KMZ16_RS04420	COG1742	UPF0060 membrane protein
KMZ16_RS04440	COG4842	Belongs to the WXG100 family
KMZ16_RS04445	COG1486	melibiose metabolic process
KMZ16_RS04450	COG1737	Transcriptional regulator
KMZ16_RS04455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KMZ16_RS04455	COG1263	PTS System
KMZ16_RS04460	COG5434	Belongs to the glycosyl hydrolase 28 family
KMZ16_RS04465	COG1132	(ABC) transporter
KMZ16_RS04470	COG1132	(ABC) transporter
KMZ16_RS04475	COG2259	Doxx family
KMZ16_RS04480	COG2514	catechol 2,3-dioxygenase activity
KMZ16_RS04485	COG4585	Histidine kinase
KMZ16_RS04490	COG2197	response regulator
KMZ16_RS04495	COG1131	(ABC) transporter
KMZ16_RS04500	COG1511	domain protein
KMZ16_RS04500	COG0842	Transport permease protein
KMZ16_RS04505	COG0842	Transport permease protein
KMZ16_RS04510	COG1695	Transcriptional regulator
KMZ16_RS04515	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KMZ16_RS04520	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KMZ16_RS04525	COG2318	DinB family
KMZ16_RS04535	COG1846	Transcriptional regulator
KMZ16_RS04540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KMZ16_RS04540	COG0392	lysyltransferase activity
KMZ16_RS04545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KMZ16_RS04550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMZ16_RS04555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMZ16_RS04560	COG0384	phenazine biosynthesis protein PhzF
KMZ16_RS04565	COG0778	Nitroreductase
KMZ16_RS04580	COG1090	epimerase
KMZ16_RS04585	COG2137	regulation of response to DNA damage stimulus
KMZ16_RS04595	COG2814	Major facilitator Superfamily
KMZ16_RS04610	COG3103	Sh3 type 3 domain protein
KMZ16_RS04615	COG5658	integral membrane protein
KMZ16_RS04620	COG0596	Alpha beta hydrolase
KMZ16_RS04625	COG0463	Glycosyl transferase, family 2
KMZ16_RS04630	COG4485	Bacterial membrane protein, YfhO
KMZ16_RS04635	COG1988	membrane-bound metal-dependent
KMZ16_RS04640	COG1194	a g-specific adenine glycosylase
KMZ16_RS04650	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS04665	COG3557	Belongs to the UPF0374 family
KMZ16_RS04670	COG1132	(ABC) transporter
KMZ16_RS04675	COG4129	membrane
KMZ16_RS04680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KMZ16_RS04685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KMZ16_RS04690	COG0735	belongs to the Fur family
KMZ16_RS04800	COG4326	sporulation control protein
KMZ16_RS04810	COG5577	PFAM Coat F domain
KMZ16_RS04815	COG3340	Belongs to the peptidase S51 family
KMZ16_RS04820	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KMZ16_RS04825	COG0277	FAD linked oxidase domain protein
KMZ16_RS04835	COG0753	catalase activity
KMZ16_RS04840	COG1116	anion transmembrane transporter activity
KMZ16_RS04845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KMZ16_RS04850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KMZ16_RS04855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMZ16_RS04865	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KMZ16_RS04875	COG1476	TRANSCRIPTIONal
KMZ16_RS04885	COG3382	B3 4 domain protein
KMZ16_RS04890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KMZ16_RS04900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KMZ16_RS04905	COG0789	Transcriptional regulator
KMZ16_RS04910	COG1664	Polymer-forming cytoskeletal
KMZ16_RS04915	COG1664	Polymer-forming cytoskeletal
KMZ16_RS04920	COG2766	serine protein kinase
KMZ16_RS04925	COG2718	Belongs to the UPF0229 family
KMZ16_RS04930	COG1846	Transcriptional regulator
KMZ16_RS04935	COG1566	PFAM secretion protein HlyD family protein
KMZ16_RS04940	COG2814	Major facilitator Superfamily
KMZ16_RS04945	COG0655	NAD(P)H dehydrogenase (quinone) activity
KMZ16_RS04965	COG1725	Transcriptional regulator
KMZ16_RS04970	COG1131	(ABC) transporter
KMZ16_RS04975	COG1131	(ABC) transporter
KMZ16_RS04980	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KMZ16_RS04985	COG1278	Cold shock
KMZ16_RS04990	COG1464	Belongs to the NlpA lipoprotein family
KMZ16_RS04995	COG3706	GGDEF domain
KMZ16_RS05000	COG1823	symporter activity
KMZ16_RS05020	COG5577	PFAM Coat F domain
KMZ16_RS05025	COG0737	Belongs to the 5'-nucleotidase family
KMZ16_RS05025	COG1525	nuclease
KMZ16_RS05025	COG4085	toxin activity
KMZ16_RS05030	COG3764	Sortase (surface protein transpeptidase)
KMZ16_RS05035	COG0564	pseudouridine synthase activity
KMZ16_RS05045	COG0517	IMP dehydrogenase activity
KMZ16_RS05050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KMZ16_RS05055	COG3153	acetyltransferase
KMZ16_RS05055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KMZ16_RS05060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KMZ16_RS05065	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KMZ16_RS05070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KMZ16_RS05075	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KMZ16_RS05080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KMZ16_RS05085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KMZ16_RS05090	COG4585	Histidine kinase
KMZ16_RS05090	COG2203	Gaf domain
KMZ16_RS05095	COG2197	response regulator
KMZ16_RS05100	COG0431	NADPH-dependent FMN reductase
KMZ16_RS05115	COG1388	LysM domain
KMZ16_RS05115	COG0791	NLP P60 protein
KMZ16_RS05120	COG1959	2 iron, 2 sulfur cluster binding
KMZ16_RS05125	COG0668	transmembrane transport
KMZ16_RS05130	COG2719	SpoVR family
KMZ16_RS05135	COG1785	Belongs to the alkaline phosphatase family
KMZ16_RS05140	COG1388	LysM domain
KMZ16_RS05140	COG0791	NLP P60 protein
KMZ16_RS05145	COG0583	DNA-binding transcription factor activity
KMZ16_RS05150	COG0372	Belongs to the citrate synthase family
KMZ16_RS05155	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS05160	COG0531	amino acid
KMZ16_RS05165	COG0733	neurotransmitter:sodium symporter activity
KMZ16_RS05170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KMZ16_RS05175	COG0456	acetyltransferase
KMZ16_RS05190	COG1595	DNA-templated transcription, initiation
KMZ16_RS05195	COG0667	Aldo Keto reductase
KMZ16_RS05200	COG0204	Acyl-transferase
KMZ16_RS05205	COG1253	flavin adenine dinucleotide binding
KMZ16_RS05210	COG0789	Transcriptional regulator
KMZ16_RS05215	COG0436	Aminotransferase
KMZ16_RS05220	COG1253	flavin adenine dinucleotide binding
KMZ16_RS05225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KMZ16_RS05230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KMZ16_RS05235	COG0584	glycerophosphoryl diester phosphodiesterase
KMZ16_RS05245	COG0668	transmembrane transport
KMZ16_RS05250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KMZ16_RS05255	COG0726	polysaccharide deacetylase
KMZ16_RS05260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KMZ16_RS05265	COG1757	Na H antiporter
KMZ16_RS05270	COG0589	response to stress
KMZ16_RS05280	COG1132	(ABC) transporter
KMZ16_RS05285	COG1132	(ABC) transporter
KMZ16_RS05290	COG0702	epimerase
KMZ16_RS05310	COG0189	ligase activity
KMZ16_RS05315	COG0189	ligase activity
KMZ16_RS05320	COG4399	Belongs to the UPF0754 family
KMZ16_RS05325	COG3679	Belongs to the UPF0342 family
KMZ16_RS05330	COG4335	DNA alkylation repair
KMZ16_RS05335	COG0561	phosphatase activity
KMZ16_RS05340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KMZ16_RS05345	COG0475	glutathione-regulated potassium exporter activity
KMZ16_RS05350	COG0490	domain, Protein
KMZ16_RS05360	COG1024	Enoyl-CoA hydratase
KMZ16_RS05370	COG4152	abc transporter atp-binding protein
KMZ16_RS05375	COG1668	transmembrane transport
KMZ16_RS05380	COG0420	3'-5' exonuclease activity
KMZ16_RS05385	COG4717	serine-type aminopeptidase activity
KMZ16_RS05390	COG3481	metal-dependent phosphohydrolase, HD sub domain
KMZ16_RS05400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KMZ16_RS05430	COG1846	Transcriptional regulator
KMZ16_RS05435	COG4980	gas vesicle protein
KMZ16_RS05450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KMZ16_RS05455	COG0537	adenosine 5'-monophosphoramidase activity
KMZ16_RS05460	COG1131	(ABC) transporter
KMZ16_RS05465	COG4473	ABC transporter
KMZ16_RS05475	COG1473	amidohydrolase
KMZ16_RS05480	COG3069	C4-dicarboxylate transmembrane transporter activity
KMZ16_RS05490	COG2329	Antibiotic biosynthesis monooxygenase
KMZ16_RS05495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KMZ16_RS05500	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KMZ16_RS05505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KMZ16_RS05510	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KMZ16_RS05515	COG1309	transcriptional regulator
KMZ16_RS05520	COG1511	domain protein
KMZ16_RS05525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KMZ16_RS05530	COG4377	Putative membrane peptidase family (DUF2324)
KMZ16_RS05540	COG1363	Peptidase, m42
KMZ16_RS05545	COG4405	Protein conserved in bacteria
KMZ16_RS05550	COG1301	dicarboxylic acid transport
KMZ16_RS05560	COG1234	tRNA 3'-trailer cleavage
KMZ16_RS05565	COG0095	Lipoate-protein ligase
KMZ16_RS05570	COG0702	epimerase
KMZ16_RS05575	COG0318	PFAM AMP-dependent synthetase and ligase
KMZ16_RS05585	COG0501	Belongs to the peptidase M48B family
KMZ16_RS05595	COG0456	acetyltransferase
KMZ16_RS05600	COG0604	alcohol dehydrogenase
KMZ16_RS05605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KMZ16_RS05610	COG0406	alpha-ribazole phosphatase activity
KMZ16_RS05615	COG0183	Belongs to the thiolase family
KMZ16_RS05620	COG0318	PFAM AMP-dependent synthetase and ligase
KMZ16_RS05625	COG1268	BioY protein
KMZ16_RS05630	COG0840	transmembrane signaling receptor activity
KMZ16_RS05635	COG0723	plastoquinol--plastocyanin reductase activity
KMZ16_RS05635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KMZ16_RS05640	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS05650	COG4903	ComK protein
KMZ16_RS05655	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS05665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMZ16_RS05680	COG0398	Pfam SNARE associated Golgi protein
KMZ16_RS05685	COG0681	Belongs to the peptidase S26 family
KMZ16_RS05690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KMZ16_RS05695	COG1846	Transcriptional regulator
KMZ16_RS05700	COG0738	Major facilitator superfamily
KMZ16_RS05705	COG0673	inositol 2-dehydrogenase activity
KMZ16_RS05710	COG0561	phosphatase activity
KMZ16_RS05715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KMZ16_RS05720	COG1609	Transcriptional regulator
KMZ16_RS05730	COG0477	Major facilitator Superfamily
KMZ16_RS05730	COG2814	Major facilitator Superfamily
KMZ16_RS05735	COG4533	DNA binding
KMZ16_RS05745	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KMZ16_RS05750	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KMZ16_RS05755	COG1074	ATP-dependent DNA helicase activity
KMZ16_RS05760	COG0420	3'-5' exonuclease activity
KMZ16_RS05765	COG0419	ATPase involved in DNA repair
KMZ16_RS05770	COG1403	HNH endonuclease
KMZ16_RS05810	COG5337	Spore coat protein CotH
KMZ16_RS05815	COG0179	Fumarylacetoacetate (FAA) hydrolase
KMZ16_RS05825	COG1404	Belongs to the peptidase S8 family
KMZ16_RS05835	COG0367	asparagine synthase
KMZ16_RS05840	COG2318	DinB family
KMZ16_RS05845	COG1562	ergosterol biosynthetic process
KMZ16_RS05850	COG0534	Mate efflux family protein
KMZ16_RS05855	COG2207	Transcriptional regulator
KMZ16_RS05855	COG1917	Cupin 2, conserved barrel domain protein
KMZ16_RS05860	COG1609	Transcriptional regulator
KMZ16_RS05865	COG0673	inositol 2-dehydrogenase activity
KMZ16_RS05870	COG2318	DinB family
KMZ16_RS05880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KMZ16_RS05885	COG1357	PFAM Pentapeptide repeats (8 copies)
KMZ16_RS05890	COG2267	carboxylic ester hydrolase activity
KMZ16_RS05895	COG0529	Catalyzes the synthesis of activated sulfate
KMZ16_RS05900	COG2046	Belongs to the sulfate adenylyltransferase family
KMZ16_RS05905	COG0175	sulfate reduction
KMZ16_RS05910	COG2045	Belongs to the ComB family
KMZ16_RS05915	COG1809	phosphosulfolactate synthase activity
KMZ16_RS05920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMZ16_RS05925	COG4948	Mandelate Racemase Muconate Lactonizing
KMZ16_RS05930	COG2814	Major facilitator Superfamily
KMZ16_RS05935	COG0454	-acetyltransferase
KMZ16_RS05940	COG2153	protein acetylation
KMZ16_RS05945	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KMZ16_RS05945	COG0646	methionine synthase
KMZ16_RS05950	COG1666	GTP binding
KMZ16_RS05955	COG2996	Protein conserved in bacteria
KMZ16_RS05975	COG1695	Transcriptional regulator
KMZ16_RS05990	COG3227	Zinc metalloprotease (Elastase)
KMZ16_RS05995	COG1307	EDD domain protein, DegV family
KMZ16_RS06000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMZ16_RS06020	COG0561	phosphatase activity
KMZ16_RS06025	COG1073	alpha beta
KMZ16_RS06030	COG2151	metal-sulfur cluster biosynthetic enzyme
KMZ16_RS06040	COG0277	FAD linked oxidase domain protein
KMZ16_RS06045	COG2271	Major facilitator Superfamily
KMZ16_RS06050	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KMZ16_RS06055	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KMZ16_RS06065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KMZ16_RS06070	COG0505	Belongs to the CarA family
KMZ16_RS06075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KMZ16_RS06080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KMZ16_RS06095	COG2267	carboxylic ester hydrolase activity
KMZ16_RS06105	COG1744	ABC transporter substrate-binding protein PnrA-like
KMZ16_RS06120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KMZ16_RS06125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KMZ16_RS06130	COG5504	Zn-dependent protease
KMZ16_RS06135	COG0444	Belongs to the ABC transporter superfamily
KMZ16_RS06140	COG4608	Belongs to the ABC transporter superfamily
KMZ16_RS06150	COG0601	transmembrane transport
KMZ16_RS06155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMZ16_RS06165	COG0180	Tryptophanyl-tRNA synthetase
KMZ16_RS06170	COG4166	transmembrane transport
KMZ16_RS06175	COG0601	transmembrane transport
KMZ16_RS06180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMZ16_RS06185	COG0444	Belongs to the ABC transporter superfamily
KMZ16_RS06190	COG4608	Belongs to the ABC transporter superfamily
KMZ16_RS06195	COG2814	Major facilitator Superfamily
KMZ16_RS06200	COG0456	acetyltransferase
KMZ16_RS06205	COG1393	Belongs to the ArsC family
KMZ16_RS06210	COG0861	Integral membrane protein TerC family
KMZ16_RS06220	COG4862	establishment of competence for transformation
KMZ16_RS06230	COG4469	Competence protein
KMZ16_RS06235	COG1164	Oligoendopeptidase f
KMZ16_RS06245	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KMZ16_RS06250	COG2346	COG2346, Truncated hemoglobins
KMZ16_RS06255	COG0741	lytic transglycosylase activity
KMZ16_RS06260	COG4116	CYTH
KMZ16_RS06270	COG2357	RelA SpoT domain protein
KMZ16_RS06275	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KMZ16_RS06280	COG0564	pseudouridine synthase activity
KMZ16_RS06285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KMZ16_RS06290	COG0475	glutathione-regulated potassium exporter activity
KMZ16_RS06290	COG0569	domain protein
KMZ16_RS06295	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KMZ16_RS06300	COG0352	thiamine-phosphate diphosphorylase activity
KMZ16_RS06305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KMZ16_RS06310	COG2104	thiamine diphosphate biosynthetic process
KMZ16_RS06315	COG2022	thiamine diphosphate biosynthetic process
KMZ16_RS06320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KMZ16_RS06325	COG0351	phosphomethylpyrimidine kinase
KMZ16_RS06330	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KMZ16_RS06395	COG2153	protein acetylation
KMZ16_RS06400	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KMZ16_RS06405	COG2382	esterase
KMZ16_RS06410	COG0626	cystathionine gamma-synthase activity
KMZ16_RS06415	COG0626	cystathionine gamma-synthase activity
KMZ16_RS06420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KMZ16_RS06425	COG5505	Protein of unknown function (DUF819)
KMZ16_RS06450	COG5444	nuclease activity
KMZ16_RS06495	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KMZ16_RS06500	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS06510	COG3711	transcriptional antiterminator
KMZ16_RS06510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KMZ16_RS06515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KMZ16_RS06515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KMZ16_RS06515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KMZ16_RS06520	COG1482	cell wall glycoprotein biosynthetic process
KMZ16_RS06530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KMZ16_RS06540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KMZ16_RS06555	COG0109	protoheme IX farnesyltransferase activity
KMZ16_RS06565	COG0726	polysaccharide deacetylase
KMZ16_RS06580	COG5504	Zn-dependent protease
KMZ16_RS06585	COG2205	protein histidine kinase activity
KMZ16_RS06595	COG3383	formate dehydrogenase (NAD+) activity
KMZ16_RS06600	COG2427	Protein of unknown function (DUF1641)
KMZ16_RS06610	COG1051	belongs to the nudix hydrolase family
KMZ16_RS06620	COG2124	cytochrome p450
KMZ16_RS06625	COG1819	glycosyl
KMZ16_RS06635	COG1587	Uroporphyrinogen-III synthase
KMZ16_RS06640	COG0390	transport system, permease component
KMZ16_RS06645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KMZ16_RS06650	COG0697	spore germination
KMZ16_RS06655	COG4297	protein containing double-stranded beta helix domain
KMZ16_RS06665	COG1252	NADH dehydrogenase
KMZ16_RS06670	COG1904	glucuronate isomerase
KMZ16_RS06675	COG2211	Major facilitator Superfamily
KMZ16_RS06685	COG1063	alcohol dehydrogenase
KMZ16_RS06690	COG1312	Catalyzes the dehydration of D-mannonate
KMZ16_RS06695	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS06700	COG2271	Major facilitator Superfamily
KMZ16_RS06705	COG1609	Transcriptional regulator
KMZ16_RS06710	COG0246	Mannitol dehydrogenase
KMZ16_RS06715	COG2721	sulfolactate sulfo-lyase activity
KMZ16_RS06720	COG0730	response to heat
KMZ16_RS06725	COG2318	DinB family
KMZ16_RS06730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KMZ16_RS06735	COG0457	Tetratricopeptide repeat
KMZ16_RS06745	COG2350	Protein conserved in bacteria
KMZ16_RS06750	COG5632	N-Acetylmuramoyl-L-alanine amidase
KMZ16_RS06750	COG3409	Peptidoglycan-binding domain 1 protein
KMZ16_RS06750	COG1388	LysM domain
KMZ16_RS06760	COG4195	phage-related replication protein
KMZ16_RS06770	COG2856	Zn peptidase
KMZ16_RS06775	COG1396	sequence-specific DNA binding
KMZ16_RS06785	COG1522	sequence-specific DNA binding
KMZ16_RS06790	COG1484	DNA-dependent DNA replication
KMZ16_RS06810	COG1595	DNA-templated transcription, initiation
KMZ16_RS06815	COG5484	DNA packaging
KMZ16_RS06815	COG3728	DNA packaging
KMZ16_RS06820	COG1783	phage Terminase large subunit
KMZ16_RS06825	COG5518	Phage portal protein
KMZ16_RS06830	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KMZ16_RS06835	COG4653	Phage capsid family
KMZ16_RS06885	COG3953	SLT domain
KMZ16_RS06885	COG5412	phage tail tape measure protein
KMZ16_RS06885	COG5412	phage tail tape measure protein
KMZ16_RS06885	COG3953	SLT domain
KMZ16_RS06890	COG1652	LysM domain
KMZ16_RS06895	COG4193	domain, Protein
KMZ16_RS06905	COG3628	GPW Gp25 family protein
KMZ16_RS06910	COG3299	homolog of phage Mu protein gp47
KMZ16_RS06915	COG3778	Protein conserved in bacteria
KMZ16_RS06955	COG5632	N-Acetylmuramoyl-L-alanine amidase
KMZ16_RS06955	COG3409	Peptidoglycan-binding domain 1 protein
KMZ16_RS06975	COG0306	phosphate transporter
KMZ16_RS06980	COG1392	Phosphate transport regulator
KMZ16_RS06985	COG0531	amino acid
KMZ16_RS06990	COG0346	lactoylglutathione lyase activity
KMZ16_RS07000	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KMZ16_RS07005	COG0463	Glycosyl transferase, family 2
KMZ16_RS07010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMZ16_RS07015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMZ16_RS07020	COG2362	D-Aminopeptidase
KMZ16_RS07025	COG0601	transmembrane transport
KMZ16_RS07030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMZ16_RS07035	COG0444	Belongs to the ABC transporter superfamily
KMZ16_RS07040	COG4166	transmembrane transport
KMZ16_RS07045	COG1619	proteins homologs of microcin C7 resistance protein MccF
KMZ16_RS07050	COG4948	Mandelate Racemase Muconate Lactonizing
KMZ16_RS07055	COG0791	NLP P60 protein
KMZ16_RS07060	COG4608	Belongs to the ABC transporter superfamily
KMZ16_RS07065	COG2706	6-phosphogluconolactonase activity
KMZ16_RS07070	COG1834	amidinotransferase
KMZ16_RS07075	COG1607	acyl-coa hydrolase
KMZ16_RS07080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KMZ16_RS07080	COG1017	nitric oxide dioxygenase activity
KMZ16_RS07090	COG2323	membrane
KMZ16_RS07095	COG2318	DinB family
KMZ16_RS07100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KMZ16_RS07105	COG2076	Multidrug Resistance protein
KMZ16_RS07110	COG2076	Multidrug Resistance protein
KMZ16_RS07115	COG0788	formyltetrahydrofolate deformylase activity
KMZ16_RS07120	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KMZ16_RS07130	COG1764	response to oxidative stress
KMZ16_RS07135	COG1846	Transcriptional regulator
KMZ16_RS07140	COG1764	response to oxidative stress
KMZ16_RS07150	COG0590	tRNA wobble adenosine to inosine editing
KMZ16_RS07155	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KMZ16_RS07160	COG1404	Belongs to the peptidase S8 family
KMZ16_RS07165	COG1366	Belongs to the anti-sigma-factor antagonist family
KMZ16_RS07170	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMZ16_RS07175	COG1122	ATPase activity
KMZ16_RS07180	COG4721	ABC-type cobalt transport system, permease component
KMZ16_RS07190	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS07195	COG3850	Histidine kinase
KMZ16_RS07195	COG5002	protein histidine kinase activity
KMZ16_RS07200	COG3212	peptidase
KMZ16_RS07205	COG3212	peptidase
KMZ16_RS07220	COG2239	Acts as a magnesium transporter
KMZ16_RS07225	COG0789	Transcriptional regulator
KMZ16_RS07240	COG1846	Transcriptional regulator
KMZ16_RS07245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KMZ16_RS07250	COG0726	polysaccharide deacetylase
KMZ16_RS07255	COG1408	metallophosphoesterase
KMZ16_RS07265	COG0463	Glycosyl transferase, family 2
KMZ16_RS07270	COG3285	dna ligase
KMZ16_RS07270	COG1793	dna ligase
KMZ16_RS07275	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KMZ16_RS07280	COG3300	MHYT domain
KMZ16_RS07280	COG5001	Diguanylate cyclase
KMZ16_RS07285	COG0586	Pfam SNARE associated Golgi protein
KMZ16_RS07290	COG0861	Integral membrane protein TerC family
KMZ16_RS07295	COG1191	sigma factor activity
KMZ16_RS07315	COG0501	Belongs to the peptidase M48B family
KMZ16_RS07320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KMZ16_RS07335	COG3594	Acyltransferase
KMZ16_RS07340	COG5002	protein histidine kinase activity
KMZ16_RS07345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KMZ16_RS07355	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KMZ16_RS07360	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KMZ16_RS07365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KMZ16_RS07370	COG0436	Aminotransferase
KMZ16_RS07375	COG1850	ribulose-bisphosphate carboxylase activity
KMZ16_RS07380	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KMZ16_RS07385	COG0235	Class ii aldolase
KMZ16_RS07390	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KMZ16_RS07395	COG3339	Conserved Protein
KMZ16_RS07410	COG3852	Histidine kinase
KMZ16_RS07415	COG1846	Transcriptional regulator
KMZ16_RS07420	COG1360	Flagellar Motor Protein
KMZ16_RS07425	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KMZ16_RS07430	COG0542	response to heat
KMZ16_RS07435	COG3949	Membrane
KMZ16_RS07440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KMZ16_RS07445	COG0720	synthase
KMZ16_RS07450	COG0602	queuosine metabolic process
KMZ16_RS07455	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KMZ16_RS07460	COG1733	regulation of RNA biosynthetic process
KMZ16_RS07465	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS07470	COG4641	Protein conserved in bacteria
KMZ16_RS07470	COG1388	LysM domain
KMZ16_RS07475	COG1388	LysM domain
KMZ16_RS07480	COG3858	chitin binding
KMZ16_RS07490	COG4873	Protein conserved in bacteria
KMZ16_RS07500	COG3773	Cell wall hydrolase
KMZ16_RS07505	COG2244	polysaccharide biosynthetic process
KMZ16_RS07510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KMZ16_RS07515	COG2217	Heavy metal translocating P-type atpase
KMZ16_RS07525	COG0006	proline dipeptidase activity
KMZ16_RS07530	COG1609	Transcriptional regulator
KMZ16_RS07535	COG3711	transcriptional antiterminator
KMZ16_RS07540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KMZ16_RS07540	COG2190	(PTS) system
KMZ16_RS07540	COG1263	PTS System
KMZ16_RS07545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KMZ16_RS07550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KMZ16_RS07560	COG1533	DNA photolyase activity
KMZ16_RS07565	COG0456	acetyltransferase
KMZ16_RS07570	COG0840	transmembrane signaling receptor activity
KMZ16_RS07575	COG2084	Dehydrogenase
KMZ16_RS07580	COG2340	Cysteine-rich secretory protein family
KMZ16_RS07585	COG0768	penicillin binding
KMZ16_RS07590	COG4191	Histidine kinase
KMZ16_RS07595	COG0436	Aminotransferase
KMZ16_RS07605	COG0835	chemotaxis
KMZ16_RS07605	COG0784	Response regulator, receiver
KMZ16_RS07615	COG2814	Major facilitator Superfamily
KMZ16_RS07620	COG1376	ErfK ybiS ycfS ynhG family protein
KMZ16_RS07625	COG1408	metallophosphoesterase
KMZ16_RS07630	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS07635	COG2200	EAL domain
KMZ16_RS07640	COG4703	Protein of unknown function (DUF1797)
KMZ16_RS07645	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KMZ16_RS07655	COG0517	IMP dehydrogenase activity
KMZ16_RS07660	COG0583	DNA-binding transcription factor activity
KMZ16_RS07665	COG0716	FMN binding
KMZ16_RS07675	COG0716	FMN binding
KMZ16_RS07680	COG2171	N-acyltransferase activity
KMZ16_RS07685	COG1473	amidohydrolase
KMZ16_RS07695	COG0668	transmembrane transport
KMZ16_RS07700	COG0450	alkyl hydroperoxide reductase
KMZ16_RS07705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KMZ16_RS07720	COG0746	molybdenum cofactor guanylyltransferase activity
KMZ16_RS07725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KMZ16_RS07730	COG0303	'Molybdopterin
KMZ16_RS07735	COG1763	Mo-molybdopterin cofactor biosynthetic process
KMZ16_RS07740	COG0314	molybdopterin synthase activity
KMZ16_RS07745	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KMZ16_RS07750	COG1132	(ABC) transporter
KMZ16_RS07755	COG1132	(ABC) transporter
KMZ16_RS07765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KMZ16_RS07770	COG1136	(ABC) transporter
KMZ16_RS07775	COG0577	efflux transmembrane transporter activity
KMZ16_RS07780	COG1349	DNA-binding transcription factor activity
KMZ16_RS07785	COG1105	Belongs to the carbohydrate kinase PfkB family
KMZ16_RS07790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KMZ16_RS07790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KMZ16_RS07790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KMZ16_RS07795	COG0681	Belongs to the peptidase S26 family
KMZ16_RS07805	COG0488	(ABC) transporter
KMZ16_RS07810	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMZ16_RS07815	COG2309	aminopeptidase activity
KMZ16_RS07825	COG1077	Cell shape determining protein MreB Mrl
KMZ16_RS07830	COG2002	toxin-antitoxin pair type II binding
KMZ16_RS07835	COG3852	Histidine kinase
KMZ16_RS07840	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KMZ16_RS07840	COG2105	PFAM AIG2 family protein
KMZ16_RS07845	COG0569	domain protein
KMZ16_RS07850	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KMZ16_RS07855	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KMZ16_RS07860	COG5503	Protein of unknown function (DUF1447)
KMZ16_RS07865	COG0561	phosphatase activity
KMZ16_RS07870	COG0242	peptide deformylase activity
KMZ16_RS07880	COG0497	DNA recombination
KMZ16_RS07885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KMZ16_RS07890	COG0022	dehydrogenase e1 component
KMZ16_RS07895	COG0508	dehydrogenase complex catalyzes the overall conversion of
KMZ16_RS07900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KMZ16_RS07905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KMZ16_RS07915	COG1982	Orn Lys Arg decarboxylase major
KMZ16_RS07920	COG4476	Belongs to the UPF0223 family
KMZ16_RS07925	COG4493	Belongs to the UPF0637 family
KMZ16_RS07935	COG0483	inositol monophosphate 1-phosphatase activity
KMZ16_RS07945	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KMZ16_RS07965	COG1595	DNA-templated transcription, initiation
KMZ16_RS07985	COG1217	gtp-binding protein TYPA
KMZ16_RS07995	COG4896	Protein conserved in bacteria
KMZ16_RS08005	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KMZ16_RS08010	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KMZ16_RS08015	COG2066	Belongs to the glutaminase family
KMZ16_RS08020	COG4838	Belongs to the UPF0358 family
KMZ16_RS08025	COG0772	Belongs to the SEDS family
KMZ16_RS08030	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KMZ16_RS08035	COG1612	heme a metabolic process
KMZ16_RS08040	COG0109	protoheme IX farnesyltransferase activity
KMZ16_RS08045	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KMZ16_RS08045	COG2010	Cytochrome c
KMZ16_RS08050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KMZ16_RS08055	COG1845	cytochrome c oxidase, subunit III
KMZ16_RS08060	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KMZ16_RS08065	COG3336	cytochrome c oxidase
KMZ16_RS08075	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KMZ16_RS08080	COG2340	Cysteine-rich secretory protein family
KMZ16_RS08095	COG3679	Belongs to the UPF0342 family
KMZ16_RS08100	COG4471	UPF0298 protein
KMZ16_RS08105	COG0742	ribosomal rna small subunit methyltransferase
KMZ16_RS08110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KMZ16_RS08115	COG3314	Sporulation integral membrane protein YlbJ
KMZ16_RS08120	COG1752	Esterase of the alpha-beta hydrolase superfamily
KMZ16_RS08125	COG3480	Lon protease (S16) C-terminal proteolytic domain
KMZ16_RS08130	COG1323	Belongs to the UPF0348 family
KMZ16_RS08140	COG1399	metal-binding, possibly nucleic acid-binding protein
KMZ16_RS08155	COG0454	-acetyltransferase
KMZ16_RS08160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMZ16_RS08165	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KMZ16_RS08170	COG2001	Belongs to the MraZ family
KMZ16_RS08175	COG0275	rRNA processing
KMZ16_RS08180	COG4839	cell division protein FtsL
KMZ16_RS08185	COG0768	penicillin binding
KMZ16_RS08190	COG0768	penicillin binding
KMZ16_RS08195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KMZ16_RS08200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KMZ16_RS08205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KMZ16_RS08210	COG0772	Belongs to the SEDS family
KMZ16_RS08215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KMZ16_RS08220	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KMZ16_RS08225	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KMZ16_RS08230	COG3879	Bacterial protein of unknown function (DUF881)
KMZ16_RS08235	COG3879	Bacterial protein of unknown function (DUF881)
KMZ16_RS08240	COG3856	small basic protein
KMZ16_RS08245	COG0849	cell division
KMZ16_RS08250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KMZ16_RS08255	COG1404	Belongs to the peptidase S8 family
KMZ16_RS08255	COG4412	M6 family metalloprotease domain protein
KMZ16_RS08265	COG1191	sigma factor activity
KMZ16_RS08270	COG1191	sigma factor activity
KMZ16_RS08275	COG1119	ATPase activity
KMZ16_RS08280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KMZ16_RS08285	COG1873	PFAM PRC-barrel domain
KMZ16_RS08290	COG1496	oxidoreductase activity
KMZ16_RS08295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KMZ16_RS08300	COG1799	cell septum assembly
KMZ16_RS08305	COG0762	integral membrane protein
KMZ16_RS08310	COG2302	S4 RNA-binding domain
KMZ16_RS08315	COG3599	regulation of cell shape
KMZ16_RS08320	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KMZ16_RS08325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KMZ16_RS08330	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KMZ16_RS08335	COG0564	pseudouridine synthase activity
KMZ16_RS08340	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KMZ16_RS08345	COG2233	PERMEase
KMZ16_RS08350	COG0540	Belongs to the ATCase OTCase family
KMZ16_RS08355	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KMZ16_RS08360	COG0505	Belongs to the CarA family
KMZ16_RS08365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KMZ16_RS08370	COG0543	2 iron, 2 sulfur cluster binding
KMZ16_RS08375	COG0167	dihydroorotate dehydrogenase activity
KMZ16_RS08380	COG0284	orotidine-5'-phosphate decarboxylase activity
KMZ16_RS08385	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KMZ16_RS08390	COG0175	sulfate reduction
KMZ16_RS08395	COG0306	phosphate transporter
KMZ16_RS08400	COG2046	Belongs to the sulfate adenylyltransferase family
KMZ16_RS08405	COG0529	Catalyzes the synthesis of activated sulfate
KMZ16_RS08410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KMZ16_RS08415	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KMZ16_RS08420	COG1648	precorrin-2 dehydrogenase activity
KMZ16_RS08425	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KMZ16_RS08430	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KMZ16_RS08435	COG1561	YicC-like family, N-terminal region
KMZ16_RS08445	COG0194	GDP metabolic process
KMZ16_RS08450	COG1758	RNA polymerase activity
KMZ16_RS08455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KMZ16_RS08460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KMZ16_RS08465	COG0242	peptide deformylase activity
KMZ16_RS08470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KMZ16_RS08475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KMZ16_RS08475	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KMZ16_RS08480	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KMZ16_RS08485	COG0631	protein serine/threonine phosphatase activity
KMZ16_RS08490	COG2815	serine threonine protein kinase
KMZ16_RS08490	COG0515	serine threonine protein kinase
KMZ16_RS08495	COG1162	GTPase activity
KMZ16_RS08500	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KMZ16_RS08505	COG1564	THIamine pyrophosphokinase
KMZ16_RS08515	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KMZ16_RS08520	COG1302	Protein conserved in bacteria
KMZ16_RS08525	COG1461	Dihydroxyacetone kinase
KMZ16_RS08530	COG1760	l-serine dehydratase
KMZ16_RS08535	COG1760	l-serine dehydratase
KMZ16_RS08540	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KMZ16_RS08545	COG1349	DNA-binding transcription factor activity
KMZ16_RS08545	COG2050	protein possibly involved in aromatic compounds catabolism
KMZ16_RS08550	COG0416	fatty acid biosynthetic process
KMZ16_RS08555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KMZ16_RS08560	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS08570	COG0571	ribonuclease III activity
KMZ16_RS08575	COG1196	nuclear chromosome segregation
KMZ16_RS08580	COG0552	protein localization to endoplasmic reticulum
KMZ16_RS08590	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KMZ16_RS08595	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KMZ16_RS08600	COG0228	four-way junction DNA binding
KMZ16_RS08605	COG1837	Belongs to the UPF0109 family
KMZ16_RS08615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KMZ16_RS08620	COG0336	Belongs to the RNA methyltransferase TrmD family
KMZ16_RS08625	COG0335	large ribosomal subunit rRNA binding
KMZ16_RS08630	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KMZ16_RS08635	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KMZ16_RS08645	COG2257	FlhB HrpN YscU SpaS Family
KMZ16_RS08650	COG0045	succinate-CoA ligase (ADP-forming) activity
KMZ16_RS08655	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KMZ16_RS08660	COG0758	DNA mediated transformation
KMZ16_RS08665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KMZ16_RS08670	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KMZ16_RS08675	COG4974	Belongs to the 'phage' integrase family
KMZ16_RS08680	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KMZ16_RS08685	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KMZ16_RS08690	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KMZ16_RS08695	COG1815	bacterial-type flagellum-dependent cell motility
KMZ16_RS08700	COG1558	bacterial-type flagellum-dependent cell motility
KMZ16_RS08705	COG1677	Flagellar hook-basal body complex protein FliE
KMZ16_RS08710	COG1766	The M ring may be actively involved in energy transduction
KMZ16_RS08715	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KMZ16_RS08720	COG1317	bacterial-type flagellum organization
KMZ16_RS08725	COG1157	protein secretion by the type III secretion system
KMZ16_RS08730	COG2882	bacterial-type flagellum organization
KMZ16_RS08735	COG3334	PFAM MgtE intracellular
KMZ16_RS08740	COG3144	bacterial-type flagellum assembly
KMZ16_RS08745	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KMZ16_RS08750	COG4786	Flagellar basal body rod
KMZ16_RS08755	COG1582	Flagellar protein (FlbD)
KMZ16_RS08760	COG1580	Controls the rotational direction of flagella during chemotaxis
KMZ16_RS08765	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KMZ16_RS08770	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KMZ16_RS08770	COG1776	CheC inhibitor of MCP methylation
KMZ16_RS08775	COG2201	protein-glutamate methylesterase activity
KMZ16_RS08780	COG3190	flagellar
KMZ16_RS08785	COG1338	Plays a role in the flagellum-specific transport system
KMZ16_RS08790	COG1987	bacterial-type flagellum assembly
KMZ16_RS08795	COG1684	flagellar biosynthetic protein fliR
KMZ16_RS08800	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KMZ16_RS08805	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KMZ16_RS08810	COG1419	protein localization to endoplasmic reticulum
KMZ16_RS08815	COG0455	bacterial-type flagellum organization
KMZ16_RS08820	COG2201	protein-glutamate methylesterase activity
KMZ16_RS08825	COG2198	Histidine kinase
KMZ16_RS08825	COG0643	Histidine kinase
KMZ16_RS08830	COG0835	chemotaxis
KMZ16_RS08835	COG1776	CheC inhibitor of MCP methylation
KMZ16_RS08840	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KMZ16_RS08845	COG1191	sigma factor activity
KMZ16_RS08855	COG0052	Belongs to the universal ribosomal protein uS2 family
KMZ16_RS08860	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KMZ16_RS08865	COG0528	UMP kinase activity
KMZ16_RS08870	COG0233	cytoplasmic translational termination
KMZ16_RS08875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KMZ16_RS08880	COG4589	Belongs to the CDS family
KMZ16_RS08885	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KMZ16_RS08890	COG0750	zinc metalloprotease
KMZ16_RS08895	COG0442	prolyl-tRNA aminoacylation
KMZ16_RS08900	COG2176	DNA-directed DNA polymerase activity
KMZ16_RS08905	COG0779	Required for maturation of 30S ribosomal subunits
KMZ16_RS08910	COG0195	Participates in both transcription termination and antitermination
KMZ16_RS08915	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KMZ16_RS08920	COG1358	cellular component organization or biogenesis
KMZ16_RS08925	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KMZ16_RS08930	COG1550	Protein conserved in bacteria
KMZ16_RS08935	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KMZ16_RS08940	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KMZ16_RS08945	COG0196	riboflavin kinase activity
KMZ16_RS08950	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KMZ16_RS08955	COG1185	polyribonucleotide nucleotidyltransferase activity
KMZ16_RS08960	COG0726	polysaccharide deacetylase
KMZ16_RS08965	COG0612	Peptidase, M16
KMZ16_RS08970	COG1873	PFAM PRC-barrel domain
KMZ16_RS08975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMZ16_RS08980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KMZ16_RS08985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KMZ16_RS08990	COG0527	aspartate kinase activity
KMZ16_RS08995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KMZ16_RS09000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KMZ16_RS09005	COG0740	serine-type endopeptidase activity
KMZ16_RS09015	COG4980	gas vesicle protein
KMZ16_RS09015	COG1674	ftsk spoiiie
KMZ16_RS09020	COG2188	Transcriptional regulator
KMZ16_RS09025	COG2814	Major facilitator Superfamily
KMZ16_RS09030	COG0612	Peptidase, M16
KMZ16_RS09035	COG0612	Peptidase, M16
KMZ16_RS09040	COG0300	oxidoreductase activity
KMZ16_RS09055	COG1426	Protein conserved in bacteria
KMZ16_RS09060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KMZ16_RS09065	COG1058	Belongs to the CinA family
KMZ16_RS09065	COG1546	Belongs to the CinA family
KMZ16_RS09070	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KMZ16_RS09075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KMZ16_RS09080	COG1418	mRNA catabolic process
KMZ16_RS09085	COG1692	metallophosphoesterase
KMZ16_RS09090	COG2359	stage V sporulation protein S
KMZ16_RS09095	COG1063	alcohol dehydrogenase
KMZ16_RS09100	COG0156	8-amino-7-oxononanoate synthase activity
KMZ16_RS09105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KMZ16_RS09110	COG4550	Control of competence regulator ComK, YlbF/YmcA
KMZ16_RS09120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KMZ16_RS09125	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KMZ16_RS09140	COG3226	Transcriptional regulator
KMZ16_RS09145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KMZ16_RS09155	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KMZ16_RS09160	COG3321	synthase
KMZ16_RS09165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KMZ16_RS09165	COG2070	2-Nitropropane dioxygenase
KMZ16_RS09170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KMZ16_RS09175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KMZ16_RS09180	COG3425	synthase
KMZ16_RS09185	COG1024	Enoyl-CoA hydratase
KMZ16_RS09190	COG1024	Enoyl-CoA hydratase
KMZ16_RS09195	COG0300	oxidoreductase activity
KMZ16_RS09195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KMZ16_RS09195	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS09195	COG0318	PFAM AMP-dependent synthetase and ligase
KMZ16_RS09195	COG3321	synthase
KMZ16_RS09200	COG4221	oxidoreductase activity
KMZ16_RS09200	COG3321	synthase
KMZ16_RS09200	COG0300	oxidoreductase activity
KMZ16_RS09200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KMZ16_RS09205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KMZ16_RS09205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KMZ16_RS09205	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS09205	COG3321	synthase
KMZ16_RS09205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KMZ16_RS09210	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS09210	COG3321	synthase
KMZ16_RS09210	COG4221	oxidoreductase activity
KMZ16_RS09210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KMZ16_RS09215	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KMZ16_RS09215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KMZ16_RS09215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KMZ16_RS09215	COG3321	synthase
KMZ16_RS09220	COG2124	cytochrome p450
KMZ16_RS09230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KMZ16_RS09235	COG1404	Belongs to the peptidase S8 family
KMZ16_RS09245	COG4195	phage-related replication protein
KMZ16_RS09250	COG1764	response to oxidative stress
KMZ16_RS09255	COG2076	Multidrug Resistance protein
KMZ16_RS09260	COG2076	Multidrug Resistance protein
KMZ16_RS09275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KMZ16_RS09280	COG1923	regulation of RNA biosynthetic process
KMZ16_RS09295	COG1780	Probably involved in ribonucleotide reductase function
KMZ16_RS09300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KMZ16_RS09305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KMZ16_RS09310	COG4112	unkown
KMZ16_RS09315	COG0860	N-Acetylmuramoyl-L-alanine amidase
KMZ16_RS09320	COG0464	growth
KMZ16_RS09325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KMZ16_RS09330	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KMZ16_RS09335	COG0789	Transcriptional regulator
KMZ16_RS09340	COG0174	glutamine synthetase
KMZ16_RS09345	COG4974	Belongs to the 'phage' integrase family
KMZ16_RS09410	COG0463	Glycosyl transferase, family 2
KMZ16_RS09430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KMZ16_RS09445	COG3655	Transcriptional regulator
KMZ16_RS09470	COG0135	phosphoribosylanthranilate isomerase activity
KMZ16_RS09475	COG2211	Major facilitator Superfamily
KMZ16_RS09480	COG3507	Belongs to the glycosyl hydrolase 43 family
KMZ16_RS09485	COG1940	carbohydrate kinase activity
KMZ16_RS09490	COG2115	Belongs to the xylose isomerase family
KMZ16_RS09495	COG1070	Carbohydrate kinase
KMZ16_RS09505	COG1525	nuclease
KMZ16_RS09510	COG2814	Major facilitator Superfamily
KMZ16_RS09515	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KMZ16_RS09525	COG0756	dUTP diphosphatase activity
KMZ16_RS09565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KMZ16_RS09580	COG3832	glyoxalase III activity
KMZ16_RS09590	COG0697	spore germination
KMZ16_RS09595	COG0531	amino acid
KMZ16_RS09625	COG4195	phage-related replication protein
KMZ16_RS09635	COG0346	lactoylglutathione lyase activity
KMZ16_RS09645	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KMZ16_RS09650	COG1388	LysM domain
KMZ16_RS09655	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KMZ16_RS09660	COG4224	UPF0291 protein
KMZ16_RS09665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KMZ16_RS09675	COG3763	UPF0154 protein
KMZ16_RS09685	COG0785	Cytochrome C biogenesis protein
KMZ16_RS09690	COG2201	protein-glutamate methylesterase activity
KMZ16_RS09695	COG4846	Membrane protein involved in cytochrome C biogenesis
KMZ16_RS09705	COG0071	Belongs to the small heat shock protein (HSP20) family
KMZ16_RS09720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KMZ16_RS09725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KMZ16_RS09745	COG0824	Thioesterase
KMZ16_RS09755	COG4841	protein insertion into membrane
KMZ16_RS09760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KMZ16_RS09765	COG1832	CoA-binding protein
KMZ16_RS09770	COG0187	DNA topoisomerase II activity
KMZ16_RS09775	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMZ16_RS09790	COG1115	amino acid carrier protein
KMZ16_RS09805	COG5520	Belongs to the glycosyl hydrolase 30 family
KMZ16_RS09810	COG3507	Belongs to the glycosyl hydrolase 43 family
KMZ16_RS09815	COG2246	polysaccharide biosynthetic process
KMZ16_RS09820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KMZ16_RS09825	COG0586	Pfam SNARE associated Golgi protein
KMZ16_RS09830	COG2404	hydrolase activity, acting on ester bonds
KMZ16_RS09835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KMZ16_RS09840	COG1024	Enoyl-CoA hydratase
KMZ16_RS09845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KMZ16_RS09850	COG0511	ligase activity, forming carbon-carbon bonds
KMZ16_RS09855	COG0439	Biotin carboxylase
KMZ16_RS09860	COG0318	PFAM AMP-dependent synthetase and ligase
KMZ16_RS09865	COG1960	acyl-CoA dehydrogenase activity
KMZ16_RS09880	COG1649	PFAM Uncharacterised BCR, COG1649
KMZ16_RS09890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KMZ16_RS09890	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KMZ16_RS09895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KMZ16_RS09900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KMZ16_RS09905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KMZ16_RS09910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KMZ16_RS09915	COG2027	D-alanyl-D-alanine carboxypeptidase
KMZ16_RS09920	COG2017	converts alpha-aldose to the beta-anomer
KMZ16_RS09925	COG0534	Mate efflux family protein
KMZ16_RS09940	COG0582	viral genome integration into host DNA
KMZ16_RS09945	COG0166	Belongs to the GPI family
KMZ16_RS09950	COG0405	Gamma-glutamyltransferase
KMZ16_RS09955	COG0583	DNA-binding transcription factor activity
KMZ16_RS09960	COG0604	alcohol dehydrogenase
KMZ16_RS09965	COG0493	'glutamate synthase
KMZ16_RS09970	COG0069	glutamate synthase activity
KMZ16_RS09970	COG0070	glutamate synthase
KMZ16_RS09970	COG0067	glutamate synthase
KMZ16_RS09975	COG0583	DNA-binding transcription factor activity
KMZ16_RS09980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KMZ16_RS09985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMZ16_RS09995	COG0300	oxidoreductase activity
KMZ16_RS10000	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KMZ16_RS10010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KMZ16_RS10030	COG2814	Major facilitator Superfamily
KMZ16_RS10035	COG1070	Carbohydrate kinase
KMZ16_RS10040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KMZ16_RS10045	COG0243	molybdopterin cofactor binding
KMZ16_RS10080	COG0840	transmembrane signaling receptor activity
KMZ16_RS10080	COG5278	phosphoserine phosphatase activity
KMZ16_RS10085	COG2368	4-hydroxyphenylacetate
KMZ16_RS10090	COG4305	rare lipoprotein A
KMZ16_RS10095	COG3619	membrane
KMZ16_RS10100	COG3866	Pectate lyase
KMZ16_RS10105	COG2135	peptidase activity
KMZ16_RS10115	COG2140	Oxalate decarboxylase
KMZ16_RS10125	COG0456	acetyltransferase
KMZ16_RS10145	COG2720	vancomycin resistance protein
KMZ16_RS10160	COG3739	integral membrane protein
KMZ16_RS10165	COG0583	DNA-binding transcription factor activity
KMZ16_RS10170	COG0697	spore germination
KMZ16_RS10180	COG0693	protein deglycase activity
KMZ16_RS10185	COG2367	Beta-lactamase
KMZ16_RS10200	COG3848	Pyruvate phosphate dikinase
KMZ16_RS10200	COG0574	Belongs to the PEP-utilizing enzyme family
KMZ16_RS10205	COG0726	polysaccharide deacetylase
KMZ16_RS10210	COG2314	TM2 domain
KMZ16_RS10215	COG1396	sequence-specific DNA binding
KMZ16_RS10340	COG0457	Tetratricopeptide repeat
KMZ16_RS10380	COG4282	regulation of fungal-type cell wall biogenesis
KMZ16_RS10385	COG1231	oxidoreductase activity
KMZ16_RS10390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KMZ16_RS10395	COG0662	Cupin 2, conserved barrel domain protein
KMZ16_RS10395	COG2207	Transcriptional regulator
KMZ16_RS10400	COG0456	acetyltransferase
KMZ16_RS10405	COG1309	transcriptional regulator
KMZ16_RS10410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KMZ16_RS10415	COG3708	Transcriptional regulator
KMZ16_RS10420	COG2378	regulation of single-species biofilm formation
KMZ16_RS10430	COG0640	Transcriptional regulator
KMZ16_RS10435	COG0741	lytic transglycosylase activity
KMZ16_RS10440	COG2322	membrane
KMZ16_RS10460	COG3239	Fatty acid desaturase
KMZ16_RS10465	COG4585	Histidine kinase
KMZ16_RS10470	COG2197	response regulator
KMZ16_RS10475	COG1388	LysM domain
KMZ16_RS10475	COG3584	3D domain protein
KMZ16_RS10480	COG0514	ATP-dependent DNA helicase (RecQ)
KMZ16_RS10490	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KMZ16_RS10495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KMZ16_RS10510	COG0071	Belongs to the small heat shock protein (HSP20) family
KMZ16_RS10535	COG1012	belongs to the aldehyde dehydrogenase family
KMZ16_RS10540	COG1657	PFAM Prenyltransferase squalene oxidase
KMZ16_RS10545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KMZ16_RS10550	COG0733	neurotransmitter:sodium symporter activity
KMZ16_RS10555	COG0385	Bile acid
KMZ16_RS10560	COG0508	dehydrogenase complex catalyzes the overall conversion of
KMZ16_RS10565	COG0567	Dehydrogenase, E1 component
KMZ16_RS10570	COG4548	von Willebrand factor, type A
KMZ16_RS10575	COG0714	Associated with various cellular activities
KMZ16_RS10580	COG2032	superoxide dismutase activity
KMZ16_RS10585	COG1388	LysM domain
KMZ16_RS10585	COG0791	NLP P60 protein
KMZ16_RS10590	COG1819	glycosyl
KMZ16_RS10595	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KMZ16_RS10600	COG0534	Mate efflux family protein
KMZ16_RS10605	COG1366	Belongs to the anti-sigma-factor antagonist family
KMZ16_RS10610	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KMZ16_RS10615	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KMZ16_RS10625	COG2962	Rard protein
KMZ16_RS10640	COG2610	gluconate transmembrane transporter activity
KMZ16_RS10645	COG1942	4-Oxalocrotonate Tautomerase
KMZ16_RS10650	COG1733	regulation of RNA biosynthetic process
KMZ16_RS10655	COG0778	Nitroreductase
KMZ16_RS10660	COG0400	carboxylic ester hydrolase activity
KMZ16_RS10665	COG0346	lactoylglutathione lyase activity
KMZ16_RS10675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMZ16_RS10680	COG3409	Peptidoglycan-binding domain 1 protein
KMZ16_RS10680	COG0793	Belongs to the peptidase S41A family
KMZ16_RS10685	COG2226	methyltransferase
KMZ16_RS10695	COG1876	peptidase activity
KMZ16_RS10700	COG0813	purine-nucleoside phosphorylase activity
KMZ16_RS10715	COG0671	phosphoesterase, PA-phosphatase related
KMZ16_RS10735	COG4479	Belongs to the UPF0346 family
KMZ16_RS10745	COG1509	lysine 2,3-aminomutase activity
KMZ16_RS10750	COG0456	acetyltransferase
KMZ16_RS10755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KMZ16_RS10760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KMZ16_RS10765	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KMZ16_RS10770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KMZ16_RS10785	COG0456	acetyltransferase
KMZ16_RS10790	COG0463	Glycosyl transferase, family 2
KMZ16_RS10805	COG4641	Protein conserved in bacteria
KMZ16_RS10810	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
KMZ16_RS10815	COG1086	Polysaccharide biosynthesis protein
KMZ16_RS10820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KMZ16_RS10825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KMZ16_RS10830	COG1846	Transcriptional regulator
KMZ16_RS10835	COG0534	Mate efflux family protein
KMZ16_RS10845	COG4698	Protein conserved in bacteria
KMZ16_RS10850	COG2755	lipolytic protein G-D-S-L family
KMZ16_RS10855	COG1999	signal sequence binding
KMZ16_RS10865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KMZ16_RS10870	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KMZ16_RS10875	COG1272	protein, Hemolysin III
KMZ16_RS10880	COG0204	Acyl-transferase
KMZ16_RS10885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KMZ16_RS10890	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KMZ16_RS10895	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KMZ16_RS10905	COG2136	Putative SAM-dependent methyltransferase
KMZ16_RS10905	COG2521	methyltransferase
KMZ16_RS10915	COG0129	dihydroxy-acid dehydratase activity
KMZ16_RS10920	COG1413	lyase activity
KMZ16_RS10925	COG1418	mRNA catabolic process
KMZ16_RS10930	COG0386	Belongs to the glutathione peroxidase family
KMZ16_RS10935	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KMZ16_RS10940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KMZ16_RS10950	COG1278	Cold shock
KMZ16_RS10970	COG0328	RNA-DNA hybrid ribonuclease activity
KMZ16_RS10975	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KMZ16_RS10980	COG0328	RNA-DNA hybrid ribonuclease activity
KMZ16_RS10990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KMZ16_RS11005	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KMZ16_RS11015	COG1755	Isoprenylcysteine carboxyl methyltransferase
KMZ16_RS11020	COG3424	synthase
KMZ16_RS11025	COG2233	PERMEase
KMZ16_RS11030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KMZ16_RS11035	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KMZ16_RS11045	COG0800	Aldolase
KMZ16_RS11050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KMZ16_RS11055	COG1609	Transcriptional regulator
KMZ16_RS11060	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KMZ16_RS11065	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS11070	COG1199	ATP-dependent helicase activity
KMZ16_RS11085	COG0116	Belongs to the methyltransferase superfamily
KMZ16_RS11100	COG4474	Belongs to the UPF0398 family
KMZ16_RS11115	COG3359	exonuclease
KMZ16_RS11120	COG1111	helicase
KMZ16_RS11120	COG1205	dead DEAH box helicase
KMZ16_RS11125	COG2190	(PTS) system
KMZ16_RS11130	COG0071	Belongs to the small heat shock protein (HSP20) family
KMZ16_RS11165	COG3331	DNA recombination
KMZ16_RS11170	COG4499	WXG100 protein secretion system (Wss), protein YukC
KMZ16_RS11170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KMZ16_RS11180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KMZ16_RS11185	COG3935	DnaD domain protein
KMZ16_RS11190	COG0017	Asparaginyl-tRNA synthetase
KMZ16_RS11195	COG0436	Aminotransferase
KMZ16_RS11200	COG5353	protein conserved in bacteria
KMZ16_RS11210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KMZ16_RS11210	COG1199	ATP-dependent helicase activity
KMZ16_RS11215	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KMZ16_RS11220	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KMZ16_RS11225	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KMZ16_RS11230	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KMZ16_RS11230	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KMZ16_RS11235	COG0617	tRNA 3'-terminal CCA addition
KMZ16_RS11240	COG0438	transferase activity, transferring glycosyl groups
KMZ16_RS11245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KMZ16_RS11250	COG1803	Methylglyoxal synthase
KMZ16_RS11255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KMZ16_RS11260	COG1694	Mazg nucleotide pyrophosphohydrolase
KMZ16_RS11265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMZ16_RS11275	COG4347	Protein of unknown function (DUF1405)
KMZ16_RS11280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KMZ16_RS11280	COG2010	Cytochrome c
KMZ16_RS11285	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KMZ16_RS11290	COG0723	plastoquinol--plastocyanin reductase activity
KMZ16_RS11300	COG5582	Belongs to the UPF0302 family
KMZ16_RS11305	COG0457	Tetratricopeptide repeat
KMZ16_RS11310	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KMZ16_RS11315	COG0287	Prephenate dehydrogenase
KMZ16_RS11325	COG0159	tryptophan synthase activity
KMZ16_RS11330	COG0133	tryptophan synthase activity
KMZ16_RS11335	COG0135	phosphoribosylanthranilate isomerase activity
KMZ16_RS11345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KMZ16_RS11350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KMZ16_RS11355	COG4401	Chorismate mutase type I
KMZ16_RS11360	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KMZ16_RS11365	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KMZ16_RS11370	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KMZ16_RS11375	COG0105	UTP biosynthetic process
KMZ16_RS11380	COG0142	geranyltranstransferase activity
KMZ16_RS11385	COG2226	methyltransferase
KMZ16_RS11390	COG0142	geranyltranstransferase activity
KMZ16_RS11400	COG0302	gtp cyclohydrolase
KMZ16_RS11405	COG0776	regulation of translation
KMZ16_RS11410	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KMZ16_RS11425	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KMZ16_RS11430	COG1160	GTP binding
KMZ16_RS11455	COG1304	FMN binding
KMZ16_RS11460	COG0539	negative regulation of cytoplasmic translation
KMZ16_RS11465	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KMZ16_RS11475	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KMZ16_RS11480	COG2959	enzyme of heme biosynthesis
KMZ16_RS11485	COG3409	Peptidoglycan-binding domain 1 protein
KMZ16_RS11485	COG3773	Cell wall hydrolase
KMZ16_RS11490	COG2339	peptidase activity
KMZ16_RS11495	COG0492	ferredoxin-NADP+ reductase activity
KMZ16_RS11500	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KMZ16_RS11505	COG4862	establishment of competence for transformation
KMZ16_RS11510	COG1408	metallophosphoesterase
KMZ16_RS11520	COG1388	LysM domain
KMZ16_RS11525	COG1266	CAAX protease self-immunity
KMZ16_RS11530	COG0514	ATP-dependent DNA helicase (RecQ)
KMZ16_RS11535	COG4955	Helix-turn-helix domain
KMZ16_RS11540	COG1141	Ferredoxin
KMZ16_RS11545	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KMZ16_RS11550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KMZ16_RS11555	COG0710	3-dehydroquinate dehydratase activity
KMZ16_RS11565	COG1595	DNA-templated transcription, initiation
KMZ16_RS11570	COG5002	protein histidine kinase activity
KMZ16_RS11575	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS11580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KMZ16_RS11585	COG1333	cytochrome c biogenesis protein
KMZ16_RS11590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KMZ16_RS11595	COG1187	pseudouridine synthase activity
KMZ16_RS11600	COG0700	Nucleoside recognition
KMZ16_RS11605	COG2715	membrane protein required for spore maturation
KMZ16_RS11610	COG1686	Belongs to the peptidase S11 family
KMZ16_RS11620	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KMZ16_RS11625	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KMZ16_RS11630	COG1547	Domain of unknown function (DUF309)
KMZ16_RS11635	COG0456	acetyltransferase
KMZ16_RS11640	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KMZ16_RS11645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KMZ16_RS11645	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KMZ16_RS11650	COG0307	riboflavin synthase, alpha
KMZ16_RS11655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KMZ16_RS11655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KMZ16_RS11665	COG0681	Belongs to the peptidase S26 family
KMZ16_RS11695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KMZ16_RS11700	COG4086	secreted protein
KMZ16_RS11705	COG0019	diaminopimelate decarboxylase activity
KMZ16_RS11710	COG0697	spore germination
KMZ16_RS11725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KMZ16_RS11745	COG1191	sigma factor activity
KMZ16_RS11750	COG2172	sigma factor antagonist activity
KMZ16_RS11755	COG1366	Belongs to the anti-sigma-factor antagonist family
KMZ16_RS11760	COG1686	Belongs to the peptidase S11 family
KMZ16_RS11765	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KMZ16_RS11770	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KMZ16_RS11775	COG4974	Belongs to the 'phage' integrase family
KMZ16_RS11785	COG0735	belongs to the Fur family
KMZ16_RS11790	COG1300	Membrane
KMZ16_RS11800	COG0281	malic enzyme
KMZ16_RS11805	COG1757	Na H antiporter
KMZ16_RS11810	COG1027	Aspartate ammonia-lyase
KMZ16_RS11815	COG0252	asparaginase activity
KMZ16_RS11820	COG1396	sequence-specific DNA binding
KMZ16_RS11825	COG1379	DNA repair
KMZ16_RS11830	COG0494	nUDIX hydrolase
KMZ16_RS11840	COG0667	Aldo Keto reductase
KMZ16_RS11850	COG1073	alpha beta
KMZ16_RS11860	COG4918	Iron-sulphur cluster biosynthesis
KMZ16_RS11865	COG0456	acetyltransferase
KMZ16_RS11865	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KMZ16_RS11870	COG2329	Antibiotic biosynthesis monooxygenase
KMZ16_RS11875	COG0456	acetyltransferase
KMZ16_RS11885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KMZ16_RS11895	COG2211	Major facilitator Superfamily
KMZ16_RS11905	COG0346	lactoylglutathione lyase activity
KMZ16_RS11910	COG1072	(Pantothenic acid kinase))
KMZ16_RS11915	COG3048	D-serine ammonia-lyase activity
KMZ16_RS11920	COG0300	oxidoreductase activity
KMZ16_RS11925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KMZ16_RS11930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMZ16_RS11935	COG4187	Peptidase family M20/M25/M40
KMZ16_RS11940	COG1902	pentaerythritol trinitrate reductase activity
KMZ16_RS11945	COG0596	Alpha beta hydrolase
KMZ16_RS11955	COG1234	tRNA 3'-trailer cleavage
KMZ16_RS11960	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KMZ16_RS11965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KMZ16_RS11970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KMZ16_RS11980	COG0706	membrane insertase activity
KMZ16_RS11985	COG3361	conserved protein (COG2071)
KMZ16_RS11990	COG2195	Cleaves the N-terminal amino acid of tripeptides
KMZ16_RS11995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KMZ16_RS12000	COG0346	lactoylglutathione lyase activity
KMZ16_RS12010	COG1376	ErfK ybiS ycfS ynhG family protein
KMZ16_RS12015	COG4129	membrane
KMZ16_RS12020	COG1126	abc transporter atp-binding protein
KMZ16_RS12025	COG0765	amino acid transport
KMZ16_RS12030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KMZ16_RS12040	COG1597	lipid kinase activity
KMZ16_RS12045	COG2814	Major facilitator Superfamily
KMZ16_RS12050	COG4978	Transcriptional regulator
KMZ16_RS12050	COG0789	Transcriptional regulator
KMZ16_RS12055	COG0508	dehydrogenase complex catalyzes the overall conversion of
KMZ16_RS12060	COG0022	dehydrogenase e1 component
KMZ16_RS12065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KMZ16_RS12070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KMZ16_RS12075	COG3426	butyrate kinase activity
KMZ16_RS12080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KMZ16_RS12085	COG0280	phosphate acetyltransferase
KMZ16_RS12090	COG3290	protein histidine kinase activity
KMZ16_RS12090	COG3829	transcription factor binding
KMZ16_RS12100	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KMZ16_RS12105	COG2079	MmgE PrpD family protein
KMZ16_RS12110	COG0372	Belongs to the citrate synthase family
KMZ16_RS12115	COG1960	acyl-CoA dehydrogenase activity
KMZ16_RS12120	COG1250	3-hydroxyacyl-CoA dehydrogenase
KMZ16_RS12125	COG0183	Belongs to the thiolase family
KMZ16_RS12130	COG0584	glycerophosphoryl diester phosphodiesterase
KMZ16_RS12135	COG0860	N-Acetylmuramoyl-L-alanine amidase
KMZ16_RS12150	COG1902	pentaerythritol trinitrate reductase activity
KMZ16_RS12155	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS12160	COG0750	zinc metalloprotease
KMZ16_RS12165	COG0497	DNA recombination
KMZ16_RS12170	COG1438	arginine binding
KMZ16_RS12175	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KMZ16_RS12180	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KMZ16_RS12185	COG0142	geranyltranstransferase activity
KMZ16_RS12190	COG1722	exodeoxyribonuclease VII activity
KMZ16_RS12195	COG1570	exodeoxyribonuclease VII activity
KMZ16_RS12200	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KMZ16_RS12205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KMZ16_RS12210	COG1302	Protein conserved in bacteria
KMZ16_RS12215	COG0439	Biotin carboxylase
KMZ16_RS12220	COG0511	ligase activity, forming carbon-carbon bonds
KMZ16_RS12260	COG3854	ATPases associated with a variety of cellular activities
KMZ16_RS12270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KMZ16_RS12275	COG0006	proline dipeptidase activity
KMZ16_RS12280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KMZ16_RS12290	COG3872	metal-dependent enzyme
KMZ16_RS12300	COG1752	Esterase of the alpha-beta hydrolase superfamily
KMZ16_RS12305	COG1321	iron dependent repressor
KMZ16_RS12310	COG0095	Lipoate-protein ligase
KMZ16_RS12315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KMZ16_RS12320	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KMZ16_RS12325	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KMZ16_RS12330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KMZ16_RS12335	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KMZ16_RS12350	COG1396	sequence-specific DNA binding
KMZ16_RS12360	COG0681	Belongs to the peptidase S26 family
KMZ16_RS12385	COG4940	Competence protein ComGF
KMZ16_RS12395	COG4970	Tfp pilus assembly protein FimT
KMZ16_RS12400	COG4537	Required for transformation and DNA binding
KMZ16_RS12405	COG1459	type II secretion system
KMZ16_RS12410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KMZ16_RS12415	COG0517	IMP dehydrogenase activity
KMZ16_RS12420	COG0598	Magnesium transport protein CorA
KMZ16_RS12425	COG1253	flavin adenine dinucleotide binding
KMZ16_RS12430	COG1366	Belongs to the anti-sigma-factor antagonist family
KMZ16_RS12440	COG1393	Belongs to the ArsC family
KMZ16_RS12450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KMZ16_RS12460	COG0011	TIGRFAM Protein of
KMZ16_RS12470	COG2866	Carboxypeptidase
KMZ16_RS12475	COG1368	sulfuric ester hydrolase activity
KMZ16_RS12480	COG1940	carbohydrate kinase activity
KMZ16_RS12485	COG4483	Protein conserved in bacteria
KMZ16_RS12490	COG0457	Tetratricopeptide repeat
KMZ16_RS12490	COG0705	Rhomboid family
KMZ16_RS12500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KMZ16_RS12510	COG0438	transferase activity, transferring glycosyl groups
KMZ16_RS12525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KMZ16_RS12530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KMZ16_RS12535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KMZ16_RS12540	COG0581	inorganic phosphate transmembrane transporter activity
KMZ16_RS12545	COG0573	inorganic phosphate transmembrane transporter activity
KMZ16_RS12550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KMZ16_RS12555	COG0768	penicillin binding
KMZ16_RS12560	COG0477	Major facilitator Superfamily
KMZ16_RS12565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KMZ16_RS12570	COG2839	Protein conserved in bacteria
KMZ16_RS12575	COG5521	maltodextrose utilization protein MalA
KMZ16_RS12580	COG1388	LysM domain
KMZ16_RS12585	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KMZ16_RS12590	COG4709	membrane
KMZ16_RS12595	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KMZ16_RS12600	COG0735	belongs to the Fur family
KMZ16_RS12605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMZ16_RS12615	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KMZ16_RS12620	COG0513	Belongs to the DEAD box helicase family
KMZ16_RS12630	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KMZ16_RS12635	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KMZ16_RS12640	COG2384	SAM-dependent methyltransferase
KMZ16_RS12645	COG2010	Cytochrome c
KMZ16_RS12650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMZ16_RS12655	COG0358	DNA primase activity
KMZ16_RS12660	COG1671	Belongs to the UPF0178 family
KMZ16_RS12665	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KMZ16_RS12670	COG0517	IMP dehydrogenase activity
KMZ16_RS12675	COG0751	glycine-tRNA ligase activity
KMZ16_RS12680	COG0752	glycyl-tRNA synthetase alpha subunit
KMZ16_RS12685	COG1381	Involved in DNA repair and RecF pathway recombination
KMZ16_RS12695	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KMZ16_RS12700	COG0295	cytidine deaminase activity
KMZ16_RS12705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KMZ16_RS12710	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KMZ16_RS12715	COG1480	7TM receptor with intracellular HD hydrolase
KMZ16_RS12720	COG1702	phosphate starvation-inducible protein PhoH
KMZ16_RS12725	COG0561	phosphatase activity
KMZ16_RS12740	COG4864	UPF0365 protein
KMZ16_RS12745	COG1030	water channel activity
KMZ16_RS12750	COG1610	YqeY-like protein
KMZ16_RS12760	COG1283	sodium-dependent phosphate transmembrane transporter activity
KMZ16_RS12765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KMZ16_RS12770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KMZ16_RS12775	COG2264	protein methyltransferase activity
KMZ16_RS12780	COG0484	heat shock protein binding
KMZ16_RS12785	COG0443	Heat shock 70 kDa protein
KMZ16_RS12790	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KMZ16_RS12795	COG1420	regulation of RNA biosynthetic process
KMZ16_RS12800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KMZ16_RS12805	COG0481	GTPase activity
KMZ16_RS12815	COG0860	N-Acetylmuramoyl-L-alanine amidase
KMZ16_RS12820	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KMZ16_RS12825	COG0268	Binds directly to 16S ribosomal RNA
KMZ16_RS12830	COG1466	dna polymerase III delta subunit
KMZ16_RS12845	COG0658	competence protein
KMZ16_RS12845	COG2333	competence protein COMEC
KMZ16_RS12850	COG2131	deaminase
KMZ16_RS12855	COG1555	photosystem II stabilization
KMZ16_RS12855	COG1596	polysaccharide export
KMZ16_RS12860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMZ16_RS12865	COG2226	methyltransferase
KMZ16_RS12870	COG0799	negative regulation of ribosome biogenesis
KMZ16_RS12875	COG1713	HD superfamily hydrolase involved in NAD metabolism
KMZ16_RS12880	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KMZ16_RS12885	COG1534	Rna-binding protein
KMZ16_RS12890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KMZ16_RS12895	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KMZ16_RS12900	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KMZ16_RS12910	COG2755	lipolytic protein G-D-S-L family
KMZ16_RS12915	COG5632	N-Acetylmuramoyl-L-alanine amidase
KMZ16_RS12915	COG3409	Peptidoglycan-binding domain 1 protein
KMZ16_RS12920	COG0398	Pfam SNARE associated Golgi protein
KMZ16_RS12935	COG3209	COG3209 Rhs family protein
KMZ16_RS12945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KMZ16_RS12955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KMZ16_RS12960	COG0798	PFAM Bile acid sodium symporter
KMZ16_RS12965	COG0346	lactoylglutathione lyase activity
KMZ16_RS12970	COG0640	Transcriptional regulator
KMZ16_RS12975	COG3403	YqcI/YcgG family
KMZ16_RS12980	COG0457	Tetratricopeptide repeat
KMZ16_RS12995	COG5444	nuclease activity
KMZ16_RS13000	COG4282	regulation of fungal-type cell wall biogenesis
KMZ16_RS13030	COG3409	Peptidoglycan-binding domain 1 protein
KMZ16_RS13030	COG5632	N-Acetylmuramoyl-L-alanine amidase
KMZ16_RS13035	COG4824	toxin secretion phage lysis holin
KMZ16_RS13065	COG3778	Protein conserved in bacteria
KMZ16_RS13070	COG3299	homolog of phage Mu protein gp47
KMZ16_RS13075	COG3628	GPW Gp25 family protein
KMZ16_RS13085	COG4193	domain, Protein
KMZ16_RS13090	COG1652	LysM domain
KMZ16_RS13095	COG5280	Phage tail tape measure protein TP901
KMZ16_RS13095	COG3953	SLT domain
KMZ16_RS13150	COG4653	Phage capsid family
KMZ16_RS13155	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KMZ16_RS13170	COG5518	Phage portal protein
KMZ16_RS13175	COG1783	phage Terminase large subunit
KMZ16_RS13180	COG5484	DNA packaging
KMZ16_RS13215	COG3677	Transposase
KMZ16_RS13235	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KMZ16_RS13245	COG1484	DNA-dependent DNA replication
KMZ16_RS13250	COG3935	DnaD domain protein
KMZ16_RS13255	COG3723	Recombinational DNA repair protein, rece pathway
KMZ16_RS13260	COG5377	YqaJ viral recombinase family
KMZ16_RS13290	COG1476	TRANSCRIPTIONal
KMZ16_RS13295	COG3620	sequence-specific DNA binding
KMZ16_RS13305	COG0563	adenylate kinase activity
KMZ16_RS13310	COG2856	Zn peptidase
KMZ16_RS13325	COG0642	Histidine kinase
KMZ16_RS13325	COG5002	protein histidine kinase activity
KMZ16_RS13330	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS13335	COG2311	Membrane
KMZ16_RS13345	COG0454	-acetyltransferase
KMZ16_RS13350	COG2249	NAD(P)H dehydrogenase (quinone) activity
KMZ16_RS13360	COG0730	response to heat
KMZ16_RS13365	COG0425	Belongs to the sulfur carrier protein TusA family
KMZ16_RS13380	COG0425	Belongs to the sulfur carrier protein TusA family
KMZ16_RS13380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KMZ16_RS13390	COG1937	Protein conserved in bacteria
KMZ16_RS13400	COG0662	Cupin 2, conserved barrel domain protein
KMZ16_RS13415	COG4978	Transcriptional regulator
KMZ16_RS13415	COG0789	Transcriptional regulator
KMZ16_RS13420	COG2814	Major facilitator Superfamily
KMZ16_RS13425	COG0456	acetyltransferase
KMZ16_RS13430	COG1253	flavin adenine dinucleotide binding
KMZ16_RS13440	COG0697	spore germination
KMZ16_RS13445	COG0583	DNA-binding transcription factor activity
KMZ16_RS13450	COG2072	flavoprotein involved in K transport
KMZ16_RS13455	COG1230	cation diffusion facilitator family transporter
KMZ16_RS13460	COG1942	4-Oxalocrotonate Tautomerase
KMZ16_RS13465	COG0583	DNA-binding transcription factor activity
KMZ16_RS13475	COG1114	Component of the transport system for branched-chain amino acids
KMZ16_RS13480	COG1687	branched-chain amino acid
KMZ16_RS13485	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KMZ16_RS13490	COG1522	sequence-specific DNA binding
KMZ16_RS13500	COG2124	cytochrome p450
KMZ16_RS13510	COG1335	isochorismatase
KMZ16_RS13525	COG2318	DinB family
KMZ16_RS13535	COG2070	2-Nitropropane dioxygenase
KMZ16_RS13540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KMZ16_RS13565	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS13570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KMZ16_RS13575	COG3959	Transketolase, thiamine diphosphate binding domain
KMZ16_RS13585	COG0789	Transcriptional regulator
KMZ16_RS13585	COG4978	Transcriptional regulator
KMZ16_RS13590	COG2315	Protein conserved in bacteria
KMZ16_RS13600	COG3443	Belongs to the bacterial solute-binding protein 9 family
KMZ16_RS13605	COG1595	DNA-templated transcription, initiation
KMZ16_RS13610	COG0667	Aldo Keto reductase
KMZ16_RS13615	COG2851	Citrate transporter
KMZ16_RS13620	COG0583	DNA-binding transcription factor activity
KMZ16_RS13625	COG2828	Protein conserved in bacteria
KMZ16_RS13630	COG3409	Peptidoglycan-binding domain 1 protein
KMZ16_RS13635	COG5566	PFAM Mor transcription activator
KMZ16_RS13640	COG0596	Alpha beta hydrolase
KMZ16_RS13645	COG4991	sh3 domain protein
KMZ16_RS13650	COG4991	sh3 domain protein
KMZ16_RS13660	COG0346	lactoylglutathione lyase activity
KMZ16_RS13670	COG5577	PFAM Coat F domain
KMZ16_RS13675	COG1063	alcohol dehydrogenase
KMZ16_RS13685	COG5577	PFAM Coat F domain
KMZ16_RS13690	COG0789	Transcriptional regulator
KMZ16_RS13700	COG1064	alcohol dehydrogenase
KMZ16_RS13705	COG0693	protein deglycase activity
KMZ16_RS13710	COG1621	beta-fructofuranosidase activity
KMZ16_RS13720	COG3716	PTS system mannose fructose sorbose family IID component
KMZ16_RS13725	COG3715	PTS system
KMZ16_RS13730	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KMZ16_RS13735	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KMZ16_RS13740	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KMZ16_RS13740	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KMZ16_RS13750	COG1113	amino acid transport
KMZ16_RS13760	COG1378	Sugar-specific transcriptional regulator TrmB
KMZ16_RS13765	COG1595	DNA-templated transcription, initiation
KMZ16_RS13775	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KMZ16_RS13775	COG2755	lipolytic protein G-D-S-L family
KMZ16_RS13785	COG2124	cytochrome p450
KMZ16_RS13785	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KMZ16_RS13790	COG1309	transcriptional regulator
KMZ16_RS13795	COG2226	methyltransferase
KMZ16_RS13810	COG2116	formate transmembrane transporter activity
KMZ16_RS13815	COG5609	conserved protein (DUF2294)
KMZ16_RS13820	COG3383	formate dehydrogenase (NAD+) activity
KMZ16_RS13825	COG2427	Protein of unknown function (DUF1641)
KMZ16_RS13835	COG0626	cystathionine gamma-synthase activity
KMZ16_RS13840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KMZ16_RS13845	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KMZ16_RS13850	COG2226	methyltransferase
KMZ16_RS13865	COG0768	penicillin binding
KMZ16_RS13870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KMZ16_RS13875	COG0572	uridine kinase
KMZ16_RS13880	COG0826	peptidase U32
KMZ16_RS13885	COG0826	peptidase U32
KMZ16_RS13890	COG4122	O-methyltransferase activity
KMZ16_RS13895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KMZ16_RS13900	COG3906	Belongs to the UPF0473 family
KMZ16_RS13905	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KMZ16_RS13910	COG4472	Bacterial protein of unknown function (DUF965)
KMZ16_RS13915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KMZ16_RS13920	COG0628	permease
KMZ16_RS13925	COG1126	abc transporter atp-binding protein
KMZ16_RS13930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KMZ16_RS13935	COG0765	amino acid transport
KMZ16_RS13940	COG0765	amino acid transport
KMZ16_RS13955	COG3881	PFAM PRC-barrel domain
KMZ16_RS13960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KMZ16_RS13965	COG0457	Tetratricopeptide repeat
KMZ16_RS13970	COG0482	sulfurtransferase activity
KMZ16_RS13975	COG1104	cysteine desulfurase activity
KMZ16_RS13980	COG1959	2 iron, 2 sulfur cluster binding
KMZ16_RS13985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KMZ16_RS13990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KMZ16_RS14000	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KMZ16_RS14005	COG0124	histidyl-tRNA synthetase
KMZ16_RS14015	COG4991	sh3 domain protein
KMZ16_RS14015	COG3103	Sh3 type 3 domain protein
KMZ16_RS14015	COG0860	N-Acetylmuramoyl-L-alanine amidase
KMZ16_RS14020	COG1490	D-aminoacyl-tRNA deacylase activity
KMZ16_RS14025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KMZ16_RS14030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KMZ16_RS14035	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KMZ16_RS14035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KMZ16_RS14040	COG5416	Lipopolysaccharide assembly protein A domain
KMZ16_RS14045	COG0490	domain, Protein
KMZ16_RS14050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KMZ16_RS14050	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KMZ16_RS14060	COG2244	polysaccharide biosynthetic process
KMZ16_RS14065	COG2323	membrane
KMZ16_RS14075	COG1862	Preprotein translocase
KMZ16_RS14080	COG0343	queuine tRNA-ribosyltransferase activity
KMZ16_RS14085	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KMZ16_RS14095	COG2255	four-way junction helicase activity
KMZ16_RS14100	COG0632	four-way junction helicase activity
KMZ16_RS14110	COG2814	Major facilitator Superfamily
KMZ16_RS14115	COG0673	inositol 2-dehydrogenase activity
KMZ16_RS14120	COG2112	serine threonine protein kinase
KMZ16_RS14145	COG1115	amino acid carrier protein
KMZ16_RS14150	COG0217	transcriptional regulatory protein
KMZ16_RS14160	COG1388	LysM domain
KMZ16_RS14165	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KMZ16_RS14170	COG0157	Belongs to the NadC ModD family
KMZ16_RS14175	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KMZ16_RS14180	COG1104	cysteine desulfurase activity
KMZ16_RS14185	COG1827	regulation of RNA biosynthetic process
KMZ16_RS14190	COG0077	Prephenate dehydratase
KMZ16_RS14195	COG4492	Belongs to the UPF0735 family
KMZ16_RS14200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KMZ16_RS14205	COG3290	protein histidine kinase activity
KMZ16_RS14215	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KMZ16_RS14220	COG2868	ribosomal protein
KMZ16_RS14225	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KMZ16_RS14230	COG1994	Peptidase M50
KMZ16_RS14235	COG0739	heme binding
KMZ16_RS14240	COG2894	cell division
KMZ16_RS14245	COG0850	regulation of cytokinetic process
KMZ16_RS14250	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KMZ16_RS14260	COG1077	Cell shape determining protein MreB Mrl
KMZ16_RS14265	COG2003	Belongs to the UPF0758 family
KMZ16_RS14270	COG0424	maF-like protein
KMZ16_RS14280	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KMZ16_RS14285	COG0285	dihydrofolate synthase activity
KMZ16_RS14290	COG0525	valine-tRNA ligase activity
KMZ16_RS14300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KMZ16_RS14305	COG1388	LysM domain
KMZ16_RS14310	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KMZ16_RS14315	COG0113	porphobilinogen synthase activity
KMZ16_RS14320	COG1587	Uroporphyrinogen-III synthase
KMZ16_RS14325	COG0181	hydroxymethylbilane synthase activity
KMZ16_RS14330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KMZ16_RS14335	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KMZ16_RS14345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KMZ16_RS14350	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KMZ16_RS14355	COG0470	DNA polymerase III
KMZ16_RS14355	COG1067	ATP-dependent peptidase activity
KMZ16_RS14360	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KMZ16_RS14365	COG0544	peptidyl-prolyl cis-trans isomerase activity
KMZ16_RS14370	COG1477	protein flavinylation
KMZ16_RS14370	COG0457	Tetratricopeptide repeat
KMZ16_RS14375	COG0066	3-isopropylmalate dehydratase activity
KMZ16_RS14380	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KMZ16_RS14385	COG0473	3-isopropylmalate dehydrogenase activity
KMZ16_RS14390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KMZ16_RS14395	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KMZ16_RS14400	COG0440	acetolactate synthase activity
KMZ16_RS14405	COG0028	Belongs to the TPP enzyme family
KMZ16_RS14415	COG0454	-acetyltransferase
KMZ16_RS14420	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
KMZ16_RS14430	COG0622	Phosphoesterase
KMZ16_RS14435	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KMZ16_RS14440	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KMZ16_RS14445	COG5401	PFAM Sporulation and spore germination
KMZ16_RS14450	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KMZ16_RS14455	COG1846	Transcriptional regulator
KMZ16_RS14460	COG2197	response regulator
KMZ16_RS14465	COG0824	Thioesterase
KMZ16_RS14470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KMZ16_RS14475	COG1053	succinate dehydrogenase
KMZ16_RS14480	COG2009	succinate dehydrogenase
KMZ16_RS14485	COG1719	4-vinyl reductase, 4VR
KMZ16_RS14490	COG0527	aspartate kinase activity
KMZ16_RS14495	COG0322	excinuclease ABC activity
KMZ16_RS14500	COG3118	belongs to the thioredoxin family
KMZ16_RS14505	COG3534	alpha-L-arabinofuranosidase
KMZ16_RS14510	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KMZ16_RS14515	COG2086	electron transfer activity
KMZ16_RS14520	COG1024	Enoyl-CoA hydratase
KMZ16_RS14525	COG1309	transcriptional regulator
KMZ16_RS14530	COG0318	PFAM AMP-dependent synthetase and ligase
KMZ16_RS14535	COG3766	membrane
KMZ16_RS14540	COG1193	negative regulation of DNA recombination
KMZ16_RS14545	COG1796	DNA polymerase
KMZ16_RS14545	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KMZ16_RS14550	COG1286	toxin biosynthetic process
KMZ16_RS14555	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KMZ16_RS14560	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KMZ16_RS14565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KMZ16_RS14565	COG0072	phenylalanine-tRNA ligase activity
KMZ16_RS14570	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KMZ16_RS14580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KMZ16_RS14590	COG3835	regulator
KMZ16_RS14595	COG0277	FAD linked oxidase domain protein
KMZ16_RS14600	COG0247	lactate metabolic process
KMZ16_RS14605	COG0346	lactoylglutathione lyase activity
KMZ16_RS14615	COG1966	Carbon starvation protein
KMZ16_RS14620	COG3534	alpha-L-arabinofuranosidase
KMZ16_RS14625	COG0395	ABC-type sugar transport system, permease component
KMZ16_RS14630	COG1175	transmembrane transport
KMZ16_RS14635	COG1653	transport
KMZ16_RS14640	COG0371	Dehydrogenase
KMZ16_RS14645	COG0647	UMP catabolic process
KMZ16_RS14650	COG0235	Class ii aldolase
KMZ16_RS14655	COG1069	ribulokinase activity
KMZ16_RS14660	COG2160	L-arabinose isomerase activity
KMZ16_RS14665	COG3507	Belongs to the glycosyl hydrolase 43 family
KMZ16_RS14670	COG1363	Peptidase, m42
KMZ16_RS14680	COG3326	Membrane
KMZ16_RS14685	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KMZ16_RS14690	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KMZ16_RS14695	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KMZ16_RS14705	COG1346	cytolysis
KMZ16_RS14710	COG1380	Effector of murein hydrolase LrgA
KMZ16_RS14715	COG3279	Response regulator of the LytR AlgR family
KMZ16_RS14720	COG3275	phosphorelay sensor kinase activity
KMZ16_RS14725	COG1011	Hydrolase
KMZ16_RS14730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KMZ16_RS14740	COG0398	Pfam SNARE associated Golgi protein
KMZ16_RS14745	COG1484	DNA-dependent DNA replication
KMZ16_RS14750	COG3611	Membrane attachment protein
KMZ16_RS14755	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KMZ16_RS14760	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KMZ16_RS14765	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KMZ16_RS14770	COG1733	regulation of RNA biosynthetic process
KMZ16_RS14775	COG2814	Major facilitator Superfamily
KMZ16_RS14780	COG0656	L-ascorbic acid biosynthetic process
KMZ16_RS14785	COG0237	dephospho-CoA kinase activity
KMZ16_RS14795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KMZ16_RS14800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KMZ16_RS14800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KMZ16_RS14805	COG5002	protein histidine kinase activity
KMZ16_RS14810	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS14815	COG0039	L-malate dehydrogenase activity
KMZ16_RS14820	COG0538	isocitrate dehydrogenase activity
KMZ16_RS14825	COG0372	Belongs to the citrate synthase family
KMZ16_RS14830	COG2707	UPF0756 membrane protein
KMZ16_RS14835	COG0628	permease
KMZ16_RS14840	COG3030	protein affecting phage T7 exclusion by the F plasmid
KMZ16_RS14845	COG0469	pyruvate kinase activity
KMZ16_RS14850	COG0205	6-phosphofructokinase activity
KMZ16_RS14855	COG0825	malonyl-CoA metabolic process
KMZ16_RS14860	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KMZ16_RS14865	COG0281	malic enzyme
KMZ16_RS14870	COG0587	DNA-directed DNA polymerase activity
KMZ16_RS14890	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KMZ16_RS14900	COG4109	DRTGG domain
KMZ16_RS14905	COG0730	response to heat
KMZ16_RS14910	COG1473	amidohydrolase
KMZ16_RS14915	COG0196	riboflavin kinase activity
KMZ16_RS14920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMZ16_RS14925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KMZ16_RS14930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMZ16_RS14935	COG1126	abc transporter atp-binding protein
KMZ16_RS14940	COG0765	amino acid transport
KMZ16_RS14945	COG0765	amino acid transport
KMZ16_RS14950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KMZ16_RS14955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KMZ16_RS14960	COG0454	-acetyltransferase
KMZ16_RS14965	COG0583	DNA-binding transcription factor activity
KMZ16_RS14970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KMZ16_RS14975	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS14985	COG0165	Argininosuccinate lyase
KMZ16_RS14990	COG0137	argininosuccinate synthase activity
KMZ16_RS14995	COG0521	Mo-molybdopterin cofactor biosynthetic process
KMZ16_RS15000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KMZ16_RS15010	COG0827	DNA restriction-modification system
KMZ16_RS15015	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KMZ16_RS15020	COG3874	Sporulation protein YtfJ
KMZ16_RS15030	COG1714	RDD family
KMZ16_RS15035	COG0616	signal peptide processing
KMZ16_RS15040	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KMZ16_RS15045	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KMZ16_RS15050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KMZ16_RS15060	COG0301	tRNA thio-modification
KMZ16_RS15065	COG1104	cysteine desulfurase activity
KMZ16_RS15070	COG1114	Component of the transport system for branched-chain amino acids
KMZ16_RS15075	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KMZ16_RS15080	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KMZ16_RS15085	COG1309	transcriptional regulator
KMZ16_RS15090	COG1956	GAF domain-containing protein
KMZ16_RS15095	COG2203	Gaf domain
KMZ16_RS15095	COG2199	diguanylate cyclase activity
KMZ16_RS15100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KMZ16_RS15110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KMZ16_RS15115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KMZ16_RS15120	COG0454	-acetyltransferase
KMZ16_RS15125	COG0517	IMP dehydrogenase activity
KMZ16_RS15130	COG0123	including yeast histone deacetylase and acetoin utilization protein
KMZ16_RS15135	COG1360	Flagellar Motor Protein
KMZ16_RS15140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KMZ16_RS15145	COG1609	Transcriptional regulator
KMZ16_RS15150	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KMZ16_RS15150	COG1605	Chorismate mutase
KMZ16_RS15155	COG3118	belongs to the thioredoxin family
KMZ16_RS15160	COG4980	gas vesicle protein
KMZ16_RS15165	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KMZ16_RS15170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KMZ16_RS15175	COG1674	ftsk spoiiie
KMZ16_RS15180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KMZ16_RS15185	COG4848	Belongs to the UPF0354 family
KMZ16_RS15190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KMZ16_RS15205	COG1363	Peptidase, m42
KMZ16_RS15210	COG5584	Small secreted protein
KMZ16_RS15215	COG0281	malic enzyme
KMZ16_RS15220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KMZ16_RS15225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KMZ16_RS15235	COG0510	thiamine kinase activity
KMZ16_RS15240	COG1523	belongs to the glycosyl hydrolase 13 family
KMZ16_RS15245	COG1597	lipid kinase activity
KMZ16_RS15255	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KMZ16_RS15260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KMZ16_RS15265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KMZ16_RS15270	COG2252	PERMEase
KMZ16_RS15275	COG4473	ABC transporter
KMZ16_RS15280	COG1131	(ABC) transporter
KMZ16_RS15285	COG1349	DNA-binding transcription factor activity
KMZ16_RS15290	COG1187	pseudouridine synthase activity
KMZ16_RS15295	COG2244	polysaccharide biosynthetic process
KMZ16_RS15300	COG2081	HI0933 family
KMZ16_RS15305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KMZ16_RS15315	COG5578	integral membrane protein
KMZ16_RS15320	COG0673	inositol 2-dehydrogenase activity
KMZ16_RS15325	COG1653	transport
KMZ16_RS15330	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KMZ16_RS15335	COG4209	transmembrane transport
KMZ16_RS15340	COG2207	Transcriptional regulator
KMZ16_RS15345	COG1653	transport
KMZ16_RS15350	COG0395	ABC-type sugar transport system, permease component
KMZ16_RS15355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KMZ16_RS15360	COG2124	cytochrome p450
KMZ16_RS15365	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KMZ16_RS15375	COG0156	8-amino-7-oxononanoate synthase activity
KMZ16_RS15380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KMZ16_RS15390	COG1073	alpha beta
KMZ16_RS15395	COG1609	Transcriptional regulator
KMZ16_RS15400	COG1653	transport
KMZ16_RS15405	COG1175	transmembrane transport
KMZ16_RS15410	COG0395	ABC-type sugar transport system, permease component
KMZ16_RS15415	COG1486	melibiose metabolic process
KMZ16_RS15420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KMZ16_RS15425	COG0495	leucyl-tRNA aminoacylation
KMZ16_RS15435	COG2202	Pas domain
KMZ16_RS15435	COG1366	Belongs to the anti-sigma-factor antagonist family
KMZ16_RS15440	COG2814	Major facilitator Superfamily
KMZ16_RS15445	COG2433	Pfam Transposase IS66
KMZ16_RS15450	COG0577	efflux transmembrane transporter activity
KMZ16_RS15455	COG1136	(ABC) transporter
KMZ16_RS15460	COG2205	protein histidine kinase activity
KMZ16_RS15465	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS15470	COG0577	efflux transmembrane transporter activity
KMZ16_RS15475	COG1136	(ABC) transporter
KMZ16_RS15490	COG1131	(ABC) transporter
KMZ16_RS15495	COG1725	Transcriptional regulator
KMZ16_RS15510	COG1242	4 iron, 4 sulfur cluster binding
KMZ16_RS15515	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KMZ16_RS15525	COG2267	carboxylic ester hydrolase activity
KMZ16_RS15530	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KMZ16_RS15535	COG1113	amino acid transport
KMZ16_RS15540	COG0367	asparagine synthase
KMZ16_RS15545	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KMZ16_RS15550	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KMZ16_RS15560	COG1506	peptidase
KMZ16_RS15565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KMZ16_RS15570	COG1116	anion transmembrane transporter activity
KMZ16_RS15575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KMZ16_RS15580	COG0494	nUDIX hydrolase
KMZ16_RS15585	COG4824	toxin secretion phage lysis holin
KMZ16_RS15590	COG0783	Belongs to the Dps family
KMZ16_RS15605	COG1854	S-ribosylhomocysteine lyase activity
KMZ16_RS15610	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KMZ16_RS15615	COG0288	reversible hydration of carbon dioxide
KMZ16_RS15620	COG0254	rRNA binding
KMZ16_RS15625	COG1271	oxidase subunit
KMZ16_RS15630	COG1294	oxidase, subunit
KMZ16_RS15640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KMZ16_RS15645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KMZ16_RS15645	COG1321	iron dependent repressor
KMZ16_RS15650	COG1121	(ABC) transporter
KMZ16_RS15655	COG0803	Belongs to the bacterial solute-binding protein 9 family
KMZ16_RS15660	COG4948	Mandelate Racemase Muconate Lactonizing
KMZ16_RS15665	COG0318	PFAM AMP-dependent synthetase and ligase
KMZ16_RS15670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KMZ16_RS15675	COG0596	Alpha beta hydrolase
KMZ16_RS15680	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KMZ16_RS15685	COG1169	isochorismate synthase
KMZ16_RS15690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KMZ16_RS15695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KMZ16_RS15700	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMZ16_RS15705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KMZ16_RS15710	COG0438	transferase activity, transferring glycosyl groups
KMZ16_RS15720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KMZ16_RS15725	COG0438	transferase activity, transferring glycosyl groups
KMZ16_RS15730	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KMZ16_RS15735	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KMZ16_RS15740	COG0058	SHG alpha-glucan phosphorylase activity
KMZ16_RS15745	COG0297	glycogen (starch) synthase activity
KMZ16_RS15750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KMZ16_RS15755	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KMZ16_RS15760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KMZ16_RS15885	COG3859	Proton-coupled thiamine transporter YuaJ
KMZ16_RS15890	COG1247	-acetyltransferase
KMZ16_RS15895	COG2268	Band 7 protein
KMZ16_RS15900	COG1585	Membrane protein implicated in regulation of membrane protease activity
KMZ16_RS15905	COG2318	DinB family
KMZ16_RS15915	COG1454	alcohol dehydrogenase
KMZ16_RS15920	COG1012	belongs to the aldehyde dehydrogenase family
KMZ16_RS15925	COG1510	regulation of RNA biosynthetic process
KMZ16_RS15935	COG0569	domain protein
KMZ16_RS15940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KMZ16_RS15945	COG4682	membrane
KMZ16_RS15950	COG1705	Flagellar rod assembly protein muramidase FlgJ
KMZ16_RS15955	COG0477	Major facilitator Superfamily
KMZ16_RS15960	COG5553	Cysteine dioxygenase type I
KMZ16_RS15970	COG1968	undecaprenyl-diphosphatase activity
KMZ16_RS15975	COG0628	permease
KMZ16_RS15980	COG0673	inositol 2-dehydrogenase activity
KMZ16_RS15985	COG4806	L-rhamnose isomerase
KMZ16_RS15990	COG3254	rhamnose metabolic process
KMZ16_RS15995	COG1070	Carbohydrate kinase
KMZ16_RS16000	COG1349	DNA-binding transcription factor activity
KMZ16_RS16005	COG3347	Dehydrogenase
KMZ16_RS16005	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS16010	COG0840	transmembrane signaling receptor activity
KMZ16_RS16015	COG0840	transmembrane signaling receptor activity
KMZ16_RS16020	COG0840	transmembrane signaling receptor activity
KMZ16_RS16025	COG0840	transmembrane signaling receptor activity
KMZ16_RS16040	COG0432	Pfam Uncharacterised protein family UPF0047
KMZ16_RS16050	COG0366	Alpha amylase catalytic
KMZ16_RS16055	COG1253	flavin adenine dinucleotide binding
KMZ16_RS16060	COG2738	Putative neutral zinc metallopeptidase
KMZ16_RS16075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KMZ16_RS16090	COG0166	Belongs to the GPI family
KMZ16_RS16095	COG1979	alcohol dehydrogenase
KMZ16_RS16100	COG1979	alcohol dehydrogenase
KMZ16_RS16105	COG2155	Conserved Protein
KMZ16_RS16110	COG1098	S1 RNA binding domain
KMZ16_RS16115	COG0436	Aminotransferase
KMZ16_RS16120	COG1522	sequence-specific DNA binding
KMZ16_RS16125	COG2267	carboxylic ester hydrolase activity
KMZ16_RS16135	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KMZ16_RS16140	COG2205	protein histidine kinase activity
KMZ16_RS16150	COG5018	Exonuclease
KMZ16_RS16160	COG2814	Major facilitator Superfamily
KMZ16_RS16165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KMZ16_RS16170	COG3011	Protein conserved in bacteria
KMZ16_RS16180	COG3290	protein histidine kinase activity
KMZ16_RS16185	COG4565	transcriptional regulatory protein
KMZ16_RS16190	COG1744	ABC transporter substrate-binding protein PnrA-like
KMZ16_RS16195	COG3845	ABC transporter
KMZ16_RS16200	COG4603	Belongs to the binding-protein-dependent transport system permease family
KMZ16_RS16205	COG1079	Belongs to the binding-protein-dependent transport system permease family
KMZ16_RS16210	COG3493	citrate carrier protein
KMZ16_RS16220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KMZ16_RS16220	COG2111	Na H antiporter
KMZ16_RS16225	COG2111	Na H antiporter
KMZ16_RS16230	COG1006	Multisubunit Na H antiporter MnhC subunit
KMZ16_RS16235	COG0651	ATP synthesis coupled electron transport
KMZ16_RS16240	COG1863	multisubunit Na H antiporter MnhE subunit
KMZ16_RS16245	COG2212	antiporter activity
KMZ16_RS16250	COG1320	monovalent cation:proton antiporter activity
KMZ16_RS16255	COG2050	protein possibly involved in aromatic compounds catabolism
KMZ16_RS16260	COG2197	response regulator
KMZ16_RS16265	COG4585	Histidine kinase
KMZ16_RS16275	COG0142	geranyltranstransferase activity
KMZ16_RS16295	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KMZ16_RS16300	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KMZ16_RS16305	COG1335	isochorismatase
KMZ16_RS16310	COG5506	Protein of unknown function (DUF1694)
KMZ16_RS16325	COG0628	permease
KMZ16_RS16340	COG1418	mRNA catabolic process
KMZ16_RS16345	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS16355	COG1511	domain protein
KMZ16_RS16360	COG0433	COG0433 Predicted ATPase
KMZ16_RS16360	COG1674	ftsk spoiiie
KMZ16_RS16365	COG4499	WXG100 protein secretion system (Wss), protein YukC
KMZ16_RS16370	COG5417	Belongs to the EsaB family
KMZ16_RS16375	COG4842	Belongs to the WXG100 family
KMZ16_RS16380	COG2508	Transcriptional regulator
KMZ16_RS16380	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KMZ16_RS16385	COG0686	Belongs to the AlaDH PNT family
KMZ16_RS16390	COG5634	Uncharacterized conserved protein (DUF2278)
KMZ16_RS16395	COG3251	PFAM MbtH domain protein
KMZ16_RS16400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KMZ16_RS16405	COG3433	isochorismatase activity
KMZ16_RS16405	COG1535	isochorismatase
KMZ16_RS16410	COG1021	2,3-dihydroxybenzoate-AMP ligase
KMZ16_RS16415	COG1169	isochorismate synthase
KMZ16_RS16420	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS16425	COG2819	hydrolase of the alpha beta superfamily
KMZ16_RS16430	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KMZ16_RS16435	COG1268	BioY protein
KMZ16_RS16440	COG2056	Na+-H+ antiporter family
KMZ16_RS16445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KMZ16_RS16450	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KMZ16_RS16455	COG3584	3D domain protein
KMZ16_RS16470	COG1252	NADH dehydrogenase
KMZ16_RS16475	COG0492	ferredoxin-NADP+ reductase activity
KMZ16_RS16485	COG0516	GMP reductase activity
KMZ16_RS16490	COG2808	Putative FMN-binding domain
KMZ16_RS16495	COG0456	acetyltransferase
KMZ16_RS16500	COG0316	Belongs to the HesB IscA family
KMZ16_RS16505	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KMZ16_RS16510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KMZ16_RS16515	COG4844	belongs to the
KMZ16_RS16520	COG1252	NADH dehydrogenase
KMZ16_RS16525	COG4837	Protein of unknown function (DUF1462)
KMZ16_RS16530	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KMZ16_RS16535	COG0823	Involved in the tonB-independent uptake of proteins
KMZ16_RS16535	COG1506	peptidase
KMZ16_RS16535	COG4946	Tricorn protease homolog
KMZ16_RS16540	COG0083	homoserine kinase activity
KMZ16_RS16545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KMZ16_RS16550	COG0460	homoserine dehydrogenase
KMZ16_RS16560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KMZ16_RS16565	COG0647	UMP catabolic process
KMZ16_RS16570	COG2445	Protein of unknown function DUF86
KMZ16_RS16575	COG4470	Protein conserved in bacteria
KMZ16_RS16585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KMZ16_RS16590	COG0739	heme binding
KMZ16_RS16600	COG3377	Domain of unknown function (DUF1805)
KMZ16_RS16605	COG0737	Belongs to the 5'-nucleotidase family
KMZ16_RS16610	COG0730	response to heat
KMZ16_RS16615	COG1801	Protein of unknown function DUF72
KMZ16_RS16625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KMZ16_RS16630	COG2508	Transcriptional regulator
KMZ16_RS16635	COG2233	PERMEase
KMZ16_RS16640	COG2233	PERMEase
KMZ16_RS16645	COG3648	Uricase
KMZ16_RS16645	COG3195	allantoin biosynthetic process
KMZ16_RS16650	COG2351	hydroxyisourate hydrolase activity
KMZ16_RS16660	COG2080	2 iron, 2 sulfur cluster binding
KMZ16_RS16665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KMZ16_RS16670	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KMZ16_RS16675	COG2068	MobA-Related Protein
KMZ16_RS16680	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KMZ16_RS16685	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KMZ16_RS16690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KMZ16_RS16700	COG2356	endonuclease I
KMZ16_RS16705	COG3842	ATPase activity
KMZ16_RS16710	COG2188	Transcriptional regulator
KMZ16_RS16715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KMZ16_RS16720	COG0395	ABC-type sugar transport system, permease component
KMZ16_RS16725	COG1175	transmembrane transport
KMZ16_RS16730	COG1653	transport
KMZ16_RS16735	COG2222	sugar isomerase
KMZ16_RS16740	COG0322	excinuclease ABC activity
KMZ16_RS16745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KMZ16_RS16760	COG0719	Fe-S assembly protein
KMZ16_RS16765	COG0822	iron-sulfur transferase activity
KMZ16_RS16770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KMZ16_RS16775	COG0719	Fe-S assembly protein
KMZ16_RS16780	COG0396	ATPase activity
KMZ16_RS16790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KMZ16_RS16795	COG1464	Belongs to the NlpA lipoprotein family
KMZ16_RS16800	COG2011	ABC-type metal ion transport system permease component
KMZ16_RS16805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KMZ16_RS16815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KMZ16_RS16820	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KMZ16_RS16830	COG0509	glycine decarboxylation via glycine cleavage system
KMZ16_RS16835	COG1393	Belongs to the ArsC family
KMZ16_RS16840	COG1960	acyl-CoA dehydrogenase activity
KMZ16_RS16845	COG0183	Belongs to the thiolase family
KMZ16_RS16850	COG1250	3-hydroxyacyl-CoA dehydrogenase
KMZ16_RS16850	COG1024	Enoyl-CoA hydratase
KMZ16_RS16860	COG0506	proline dehydrogenase activity
KMZ16_RS16870	COG5577	PFAM Coat F domain
KMZ16_RS16875	COG1846	Transcriptional regulator
KMZ16_RS16880	COG0477	Major facilitator Superfamily
KMZ16_RS16885	COG1942	4-Oxalocrotonate Tautomerase
KMZ16_RS16890	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS16895	COG0583	DNA-binding transcription factor activity
KMZ16_RS16905	COG1120	ATPase activity
KMZ16_RS16920	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS16925	COG0783	Belongs to the Dps family
KMZ16_RS16930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMZ16_RS16935	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS16940	COG2770	Histidine kinase
KMZ16_RS16940	COG2205	protein histidine kinase activity
KMZ16_RS16950	COG1309	transcriptional regulator
KMZ16_RS16955	COG0114	fumarate hydratase activity
KMZ16_RS16965	COG0697	spore germination
KMZ16_RS16970	COG0814	amino acid
KMZ16_RS16980	COG2197	response regulator
KMZ16_RS16985	COG4585	Histidine kinase
KMZ16_RS16990	COG4758	membrane
KMZ16_RS16995	COG3595	metallopeptidase activity
KMZ16_RS17000	COG1842	Phage shock protein A
KMZ16_RS17005	COG4758	membrane
KMZ16_RS17010	COG2814	Major facilitator Superfamily
KMZ16_RS17015	COG2096	Adenosyltransferase
KMZ16_RS17020	COG1120	ATPase activity
KMZ16_RS17025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMZ16_RS17030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KMZ16_RS17035	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS17040	COG3386	PFAM SMP-30 Gluconolaconase
KMZ16_RS17045	COG2205	protein histidine kinase activity
KMZ16_RS17050	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS17060	COG1191	sigma factor activity
KMZ16_RS17070	COG2140	Oxalate decarboxylase
KMZ16_RS17080	COG0577	efflux transmembrane transporter activity
KMZ16_RS17085	COG1136	(ABC) transporter
KMZ16_RS17090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KMZ16_RS17095	COG1120	ATPase activity
KMZ16_RS17100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMZ16_RS17105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMZ16_RS17110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KMZ16_RS17115	COG0531	amino acid
KMZ16_RS17125	COG1988	membrane-bound metal-dependent
KMZ16_RS17130	COG1368	sulfuric ester hydrolase activity
KMZ16_RS17135	COG1910	domain protein
KMZ16_RS17140	COG0725	ABC transporter, periplasmic molybdate-binding protein
KMZ16_RS17145	COG4149	molybdate abc transporter
KMZ16_RS17150	COG0656	L-ascorbic acid biosynthetic process
KMZ16_RS17160	COG0025	NhaP-type Na H and K H
KMZ16_RS17165	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KMZ16_RS17170	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KMZ16_RS17175	COG3973	AAA domain
KMZ16_RS17185	COG2860	membrane
KMZ16_RS17190	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KMZ16_RS17195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KMZ16_RS17200	COG2217	Heavy metal translocating P-type atpase
KMZ16_RS17205	COG2217	Heavy metal translocating P-type atpase
KMZ16_RS17210	COG2608	mercury ion transmembrane transporter activity
KMZ16_RS17215	COG1937	Protein conserved in bacteria
KMZ16_RS17220	COG0673	inositol 2-dehydrogenase activity
KMZ16_RS17225	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KMZ16_RS17230	COG1289	transmembrane transporter activity
KMZ16_RS17240	COG2076	Multidrug Resistance protein
KMZ16_RS17245	COG1309	transcriptional regulator
KMZ16_RS17250	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS17260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KMZ16_RS17265	COG0557	exoribonuclease II activity
KMZ16_RS17270	COG1647	Serine aminopeptidase, S33
KMZ16_RS17275	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KMZ16_RS17280	COG0596	Alpha beta hydrolase
KMZ16_RS17285	COG1476	TRANSCRIPTIONal
KMZ16_RS17290	COG1396	sequence-specific DNA binding
KMZ16_RS17295	COG1396	sequence-specific DNA binding
KMZ16_RS17300	COG1733	regulation of RNA biosynthetic process
KMZ16_RS17305	COG0840	transmembrane signaling receptor activity
KMZ16_RS17310	COG1174	glycine betaine transport
KMZ16_RS17315	COG1732	Glycine betaine
KMZ16_RS17320	COG1174	glycine betaine transport
KMZ16_RS17325	COG0517	IMP dehydrogenase activity
KMZ16_RS17325	COG1125	glycine betaine transport
KMZ16_RS17335	COG1174	glycine betaine transport
KMZ16_RS17340	COG1732	Glycine betaine
KMZ16_RS17345	COG1174	glycine betaine transport
KMZ16_RS17350	COG0517	IMP dehydrogenase activity
KMZ16_RS17350	COG1125	glycine betaine transport
KMZ16_RS17355	COG1510	regulation of RNA biosynthetic process
KMZ16_RS17360	COG2095	MarC family integral membrane protein
KMZ16_RS17370	COG3064	Membrane
KMZ16_RS17375	COG4640	response to antibiotic
KMZ16_RS17380	COG0456	acetyltransferase
KMZ16_RS17385	COG0148	phosphopyruvate hydratase activity
KMZ16_RS17390	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KMZ16_RS17395	COG0149	triose-phosphate isomerase activity
KMZ16_RS17400	COG0126	phosphoglycerate kinase activity
KMZ16_RS17405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KMZ16_RS17410	COG2390	Transcriptional regulator
KMZ16_RS17420	COG1609	Transcriptional regulator
KMZ16_RS17425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMZ16_RS17435	COG0583	DNA-binding transcription factor activity
KMZ16_RS17440	COG0697	spore germination
KMZ16_RS17450	COG3858	chitin binding
KMZ16_RS17460	COG1139	Iron-sulfur cluster binding protein
KMZ16_RS17465	COG0247	lactate metabolic process
KMZ16_RS17470	COG2197	response regulator
KMZ16_RS17475	COG4585	Histidine kinase
KMZ16_RS17480	COG0842	Transport permease protein
KMZ16_RS17485	COG1131	(ABC) transporter
KMZ16_RS17490	COG0596	Alpha beta hydrolase
KMZ16_RS17495	COG2208	phosphoserine phosphatase activity
KMZ16_RS17500	COG3867	Arabinogalactan endo-beta-1,4-galactanase
KMZ16_RS17505	COG1874	Beta-galactosidase
KMZ16_RS17510	COG3833	ABC-type maltose transport systems, permease component
KMZ16_RS17515	COG1175	transmembrane transport
KMZ16_RS17525	COG1609	Transcriptional regulator
KMZ16_RS17540	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KMZ16_RS17550	COG5039	Polysaccharide pyruvyl transferase
KMZ16_RS17555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KMZ16_RS17560	COG0110	maltose O-acetyltransferase activity
KMZ16_RS17565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KMZ16_RS17570	COG2244	polysaccharide biosynthetic process
KMZ16_RS17575	COG1216	Glycosyl transferase, family 2
KMZ16_RS17580	COG5039	Polysaccharide pyruvyl transferase
KMZ16_RS17585	COG1216	Glycosyl transferase, family 2
KMZ16_RS17595	COG0438	transferase activity, transferring glycosyl groups
KMZ16_RS17600	COG1215	transferase activity, transferring glycosyl groups
KMZ16_RS17605	COG0438	transferase activity, transferring glycosyl groups
KMZ16_RS17610	COG1086	Polysaccharide biosynthesis protein
KMZ16_RS17615	COG0489	protein tyrosine kinase activity
KMZ16_RS17620	COG3944	biosynthesis protein
KMZ16_RS17625	COG1396	sequence-specific DNA binding
KMZ16_RS17630	COG2272	Belongs to the type-B carboxylesterase lipase family
KMZ16_RS17640	COG3479	Phenolic acid decarboxylase
KMZ16_RS17650	COG1794	racemase activity, acting on amino acids and derivatives
KMZ16_RS17655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KMZ16_RS17660	COG1621	beta-fructofuranosidase activity
KMZ16_RS17665	COG1621	beta-fructofuranosidase activity
KMZ16_RS17670	COG0531	amino acid
KMZ16_RS17675	COG1309	transcriptional regulator
KMZ16_RS17680	COG2076	Multidrug Resistance protein
KMZ16_RS17685	COG2076	Multidrug Resistance protein
KMZ16_RS17695	COG0277	FAD linked oxidase domain protein
KMZ16_RS17700	COG3621	Patatin-like phospholipase
KMZ16_RS17710	COG0740	serine-type endopeptidase activity
KMZ16_RS17715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KMZ16_RS17720	COG0366	Alpha amylase catalytic
KMZ16_RS17725	COG1554	hydrolase, family 65, central catalytic
KMZ16_RS17730	COG5521	maltodextrose utilization protein MalA
KMZ16_RS17735	COG3833	ABC-type maltose transport systems, permease component
KMZ16_RS17740	COG1175	transmembrane transport
KMZ16_RS17745	COG2182	Extracellular solute-binding protein
KMZ16_RS17755	COG1609	Transcriptional regulator
KMZ16_RS17760	COG1611	Belongs to the LOG family
KMZ16_RS17765	COG1694	Mazg nucleotide pyrophosphohydrolase
KMZ16_RS17770	COG0659	secondary active sulfate transmembrane transporter activity
KMZ16_RS17775	COG0288	reversible hydration of carbon dioxide
KMZ16_RS17780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMZ16_RS17785	COG0577	efflux transmembrane transporter activity
KMZ16_RS17790	COG1136	(ABC) transporter
KMZ16_RS17795	COG5002	protein histidine kinase activity
KMZ16_RS17800	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS17810	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KMZ16_RS17815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KMZ16_RS17820	COG1481	regulation of sporulation
KMZ16_RS17825	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KMZ16_RS17830	COG1660	Displays ATPase and GTPase activities
KMZ16_RS17835	COG1051	belongs to the nudix hydrolase family
KMZ16_RS17840	COG0492	ferredoxin-NADP+ reductase activity
KMZ16_RS17845	COG0791	NLP P60 protein
KMZ16_RS17845	COG3883	PFAM NLP P60 protein
KMZ16_RS17850	COG0457	Tetratricopeptide repeat
KMZ16_RS17855	COG1132	(ABC) transporter
KMZ16_RS17875	COG0140	phosphoribosyl-ATP diphosphatase activity
KMZ16_RS17875	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KMZ16_RS17880	COG0107	imidazoleglycerol-phosphate synthase activity
KMZ16_RS17885	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KMZ16_RS17890	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KMZ16_RS17895	COG0131	Imidazoleglycerol-phosphate dehydratase
KMZ16_RS17900	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KMZ16_RS17905	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KMZ16_RS17910	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KMZ16_RS17915	COG4990	cell redox homeostasis
KMZ16_RS17920	COG5297	Belongs to the glycosyl hydrolase family 6
KMZ16_RS17925	COG0110	maltose O-acetyltransferase activity
KMZ16_RS17930	COG0546	phosphoglycolate phosphatase activity
KMZ16_RS17935	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KMZ16_RS17940	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KMZ16_RS17945	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KMZ16_RS17950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KMZ16_RS17955	COG0363	glucosamine-6-phosphate deaminase activity
KMZ16_RS17960	COG2188	Transcriptional regulator
KMZ16_RS17965	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KMZ16_RS17970	COG1846	Transcriptional regulator
KMZ16_RS17975	COG2124	cytochrome p450
KMZ16_RS17985	COG1846	Transcriptional regulator
KMZ16_RS17990	COG2814	Major facilitator Superfamily
KMZ16_RS17995	COG1950	PFAM Membrane protein of
KMZ16_RS18000	COG1983	PspC domain protein
KMZ16_RS18005	COG3595	metallopeptidase activity
KMZ16_RS18020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KMZ16_RS18025	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KMZ16_RS18030	COG0556	nucleotide-excision repair
KMZ16_RS18035	COG4897	Protein conserved in bacteria
KMZ16_RS18040	COG3848	Pyruvate phosphate dikinase
KMZ16_RS18040	COG0574	Belongs to the PEP-utilizing enzyme family
KMZ16_RS18045	COG1309	transcriptional regulator
KMZ16_RS18050	COG2814	Major facilitator Superfamily
KMZ16_RS18055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMZ16_RS18065	COG0793	Belongs to the peptidase S41A family
KMZ16_RS18065	COG3409	Peptidoglycan-binding domain 1 protein
KMZ16_RS18070	COG2177	Part of the ABC transporter FtsEX involved in
KMZ16_RS18075	COG2884	Cell division ATP-binding protein ftsE
KMZ16_RS18080	COG2010	Cytochrome c
KMZ16_RS18085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMZ16_RS18095	COG0653	protein targeting
KMZ16_RS18100	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KMZ16_RS18115	COG1516	flagellar protein fliS
KMZ16_RS18120	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KMZ16_RS18125	COG1334	flagellar protein FlaG
KMZ16_RS18130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KMZ16_RS18135	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KMZ16_RS18140	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KMZ16_RS18150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KMZ16_RS18155	COG1256	bacterial-type flagellum assembly
KMZ16_RS18155	COG4786	Flagellar basal body rod
KMZ16_RS18160	COG3418	PFAM FlgN family protein
KMZ16_RS18165	COG2747	anti-sigma28 factor FlgM
KMZ16_RS18175	COG1040	competence protein
KMZ16_RS18185	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KMZ16_RS18190	COG1307	EDD domain protein, DegV family
KMZ16_RS18195	COG2197	response regulator
KMZ16_RS18200	COG4585	Histidine kinase
KMZ16_RS18205	COG1739	Uncharacterized protein family UPF0029
KMZ16_RS18210	COG1316	TRANSCRIPTIONal
KMZ16_RS18215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KMZ16_RS18220	COG0438	transferase activity, transferring glycosyl groups
KMZ16_RS18225	COG1215	transferase activity, transferring glycosyl groups
KMZ16_RS18230	COG3206	protein involved in exopolysaccharide biosynthesis
KMZ16_RS18235	COG3307	-O-antigen
KMZ16_RS18240	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMZ16_RS18245	COG0297	glycogen (starch) synthase activity
KMZ16_RS18245	COG0438	transferase activity, transferring glycosyl groups
KMZ16_RS18250	COG2244	polysaccharide biosynthetic process
KMZ16_RS18265	COG0860	N-Acetylmuramoyl-L-alanine amidase
KMZ16_RS18265	COG2247	cell wall binding repeat
KMZ16_RS18270	COG2247	cell wall binding repeat
KMZ16_RS18270	COG2385	sporulation resulting in formation of a cellular spore
KMZ16_RS18280	COG1316	TRANSCRIPTIONal
KMZ16_RS18285	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KMZ16_RS18305	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KMZ16_RS18310	COG1134	teichoic acid transport
KMZ16_RS18315	COG1682	transport, permease protein
KMZ16_RS18330	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KMZ16_RS18330	COG1215	transferase activity, transferring glycosyl groups
KMZ16_RS18335	COG0463	Glycosyl transferase, family 2
KMZ16_RS18380	COG4193	domain, Protein
KMZ16_RS18385	COG1482	cell wall glycoprotein biosynthetic process
KMZ16_RS18390	COG0697	spore germination
KMZ16_RS18395	COG0814	amino acid
KMZ16_RS18405	COG2814	Major facilitator Superfamily
KMZ16_RS18410	COG1316	TRANSCRIPTIONal
KMZ16_RS18415	COG0561	phosphatase activity
KMZ16_RS18420	COG0791	NLP P60 protein
KMZ16_RS18430	COG2843	Capsule synthesis protein
KMZ16_RS18440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KMZ16_RS18445	COG1609	Transcriptional regulator
KMZ16_RS18450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KMZ16_RS18455	COG1869	D-ribose catabolic process
KMZ16_RS18460	COG1129	ABC transporter
KMZ16_RS18465	COG1172	Belongs to the binding-protein-dependent transport system permease family
KMZ16_RS18470	COG1879	ABC-type sugar transport system periplasmic component
KMZ16_RS18475	COG3103	Sh3 type 3 domain protein
KMZ16_RS18485	COG2249	NAD(P)H dehydrogenase (quinone) activity
KMZ16_RS18490	COG3527	Alpha-acetolactate decarboxylase
KMZ16_RS18495	COG0028	Belongs to the TPP enzyme family
KMZ16_RS18500	COG0583	DNA-binding transcription factor activity
KMZ16_RS18505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KMZ16_RS18520	COG5337	Spore coat protein CotH
KMZ16_RS18530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KMZ16_RS18540	COG0405	Gamma-glutamyltransferase
KMZ16_RS18545	COG1522	sequence-specific DNA binding
KMZ16_RS18550	COG2059	Chromate
KMZ16_RS18555	COG2059	Chromate
KMZ16_RS18565	COG0655	NAD(P)H dehydrogenase (quinone) activity
KMZ16_RS18570	COG0583	DNA-binding transcription factor activity
KMZ16_RS18600	COG5444	nuclease activity
KMZ16_RS18620	COG3878	Protein conserved in bacteria
KMZ16_RS18625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMZ16_RS18630	COG4464	protein tyrosine phosphatase activity
KMZ16_RS18635	COG0489	protein tyrosine kinase activity
KMZ16_RS18640	COG3944	biosynthesis protein
KMZ16_RS18650	COG4715	Zinc finger, swim domain protein
KMZ16_RS18655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KMZ16_RS18660	COG0561	phosphatase activity
KMZ16_RS18665	COG1349	DNA-binding transcription factor activity
KMZ16_RS18670	COG0629	single-stranded DNA binding
KMZ16_RS18700	COG1970	mechanosensitive ion channel activity
KMZ16_RS18705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KMZ16_RS18710	COG0457	Tetratricopeptide repeat
KMZ16_RS18715	COG4786	Flagellar basal body rod
KMZ16_RS18720	COG4786	Flagellar basal body rod
KMZ16_RS18725	COG1077	Cell shape determining protein MreB Mrl
KMZ16_RS18730	COG1609	Transcriptional regulator
KMZ16_RS18740	COG1846	Transcriptional regulator
KMZ16_RS18745	COG2814	Major facilitator Superfamily
KMZ16_RS18750	COG3420	alginic acid biosynthetic process
KMZ16_RS18755	COG1953	Uracil, thiamine, allantoin
KMZ16_RS18760	COG0477	Major facilitator Superfamily
KMZ16_RS18765	COG1335	isochorismatase
KMZ16_RS18775	COG0004	ammonium transporteR
KMZ16_RS18780	COG0347	Belongs to the P(II) protein family
KMZ16_RS18785	COG0671	phosphoesterase, PA-phosphatase related
KMZ16_RS18795	COG0739	heme binding
KMZ16_RS18800	COG1247	-acetyltransferase
KMZ16_RS18820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KMZ16_RS18825	COG0789	Transcriptional regulator
KMZ16_RS18835	COG2910	NAD(P)H-binding
KMZ16_RS18840	COG1959	2 iron, 2 sulfur cluster binding
KMZ16_RS18845	COG0804	urea catabolic process
KMZ16_RS18850	COG0832	Belongs to the urease beta subunit family
KMZ16_RS18855	COG0831	urea catabolic process
KMZ16_RS18870	COG3237	CsbD-like
KMZ16_RS18875	COG1994	Peptidase M50
KMZ16_RS18880	COG0457	Tetratricopeptide repeat
KMZ16_RS18885	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KMZ16_RS18890	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KMZ16_RS18900	COG2304	oxidoreductase activity
KMZ16_RS18910	COG2304	oxidoreductase activity
KMZ16_RS18915	COG2385	sporulation resulting in formation of a cellular spore
KMZ16_RS18920	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KMZ16_RS18930	COG4836	Membrane
KMZ16_RS18940	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KMZ16_RS18945	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KMZ16_RS18950	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KMZ16_RS18955	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KMZ16_RS18960	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KMZ16_RS18965	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KMZ16_RS18975	COG0356	it plays a direct role in the translocation of protons across the membrane
KMZ16_RS18985	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KMZ16_RS18990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KMZ16_RS18995	COG4475	Protein of unknown function (DUF436)
KMZ16_RS19000	COG0698	ribose 5-phosphate isomerase
KMZ16_RS19005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KMZ16_RS19010	COG1971	Probably functions as a manganese efflux pump
KMZ16_RS19015	COG0009	L-threonylcarbamoyladenylate synthase
KMZ16_RS19020	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KMZ16_RS19040	COG2890	protein-(glutamine-N5) methyltransferase activity
KMZ16_RS19045	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KMZ16_RS19050	COG0346	lactoylglutathione lyase activity
KMZ16_RS19055	COG0789	Transcriptional regulator
KMZ16_RS19060	COG0679	Auxin Efflux Carrier
KMZ16_RS19065	COG0281	malic enzyme
KMZ16_RS19070	COG1435	thymidine kinase activity
KMZ16_RS19080	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KMZ16_RS19090	COG1494	fructose-1,6-bisphosphatase
KMZ16_RS19095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KMZ16_RS19100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KMZ16_RS19105	COG0191	fructose-bisphosphate aldolase activity
KMZ16_RS19110	COG2204	response regulator
KMZ16_RS19115	COG4821	SIS domain
KMZ16_RS19120	COG0504	CTP synthase activity
KMZ16_RS19125	COG3343	RNA polymerase activity
KMZ16_RS19130	COG1960	acyl-CoA dehydrogenase activity
KMZ16_RS19135	COG2181	nitrate reductase activity
KMZ16_RS19135	COG0247	lactate metabolic process
KMZ16_RS19140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KMZ16_RS19145	COG4294	response to UV
KMZ16_RS19155	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KMZ16_RS19160	COG1132	(ABC) transporter
KMZ16_RS19165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KMZ16_RS19175	COG2181	nitrate reductase activity
KMZ16_RS19180	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KMZ16_RS19185	COG1140	nitrate reductase beta subunit
KMZ16_RS19190	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMZ16_RS19195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KMZ16_RS19205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KMZ16_RS19210	COG2223	nitrite transmembrane transporter activity
KMZ16_RS19215	COG0018	arginyl-trna synthetase
KMZ16_RS19220	COG4506	Protein conserved in bacteria
KMZ16_RS19235	COG0535	radical SAM domain protein
KMZ16_RS19245	COG1131	(ABC) transporter
KMZ16_RS19250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KMZ16_RS19255	COG0612	Peptidase, M16
KMZ16_RS19260	COG0612	Peptidase, M16
KMZ16_RS19270	COG3391	amine dehydrogenase activity
KMZ16_RS19275	COG3391	amine dehydrogenase activity
KMZ16_RS19280	COG0457	Tetratricopeptide repeat
KMZ16_RS19300	COG0010	Belongs to the arginase family
KMZ16_RS19305	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KMZ16_RS19310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KMZ16_RS19320	COG1994	Peptidase M50
KMZ16_RS19325	COG1942	4-Oxalocrotonate Tautomerase
KMZ16_RS19330	COG1846	Transcriptional regulator
KMZ16_RS19335	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KMZ16_RS19345	COG0477	Major facilitator Superfamily
KMZ16_RS19350	COG1959	2 iron, 2 sulfur cluster binding
KMZ16_RS19355	COG3465	dGTPase activity
KMZ16_RS19360	COG1078	dGTPase activity
KMZ16_RS19365	COG4844	belongs to the
KMZ16_RS19375	COG0697	spore germination
KMZ16_RS19380	COG0095	Lipoate-protein ligase
KMZ16_RS19385	COG0583	DNA-binding transcription factor activity
KMZ16_RS19390	COG0280	phosphate acetyltransferase
KMZ16_RS19395	COG3253	May function as heme-dependent peroxidase
KMZ16_RS19400	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS19405	COG0436	Aminotransferase
KMZ16_RS19410	COG2814	Major facilitator Superfamily
KMZ16_RS19415	COG0151	Belongs to the GarS family
KMZ16_RS19420	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS19425	COG1917	Cupin 2, conserved barrel domain protein
KMZ16_RS19430	COG0077	Prephenate dehydratase
KMZ16_RS19435	COG2814	Major facilitator Superfamily
KMZ16_RS19440	COG0833	amino acid
KMZ16_RS19445	COG4187	Peptidase family M20/M25/M40
KMZ16_RS19450	COG1012	belongs to the aldehyde dehydrogenase family
KMZ16_RS19455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KMZ16_RS19465	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KMZ16_RS19470	COG1091	dTDP-4-dehydrorhamnose reductase activity
KMZ16_RS19475	COG1088	dTDP-glucose 4,6-dehydratase activity
KMZ16_RS19480	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KMZ16_RS19485	COG3980	spore coat polysaccharide biosynthesis protein
KMZ16_RS19490	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KMZ16_RS19495	COG2089	acid synthase
KMZ16_RS19500	COG0456	acetyltransferase
KMZ16_RS19505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KMZ16_RS19510	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KMZ16_RS19515	COG0463	Glycosyl transferase, family 2
KMZ16_RS19525	COG2363	Small membrane protein
KMZ16_RS19530	COG2233	PERMEase
KMZ16_RS19540	COG1012	belongs to the aldehyde dehydrogenase family
KMZ16_RS19545	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KMZ16_RS19550	COG1216	Glycosyl transferase, family 2
KMZ16_RS19565	COG1695	Transcriptional regulator
KMZ16_RS19570	COG0351	phosphomethylpyrimidine kinase
KMZ16_RS19580	COG1621	beta-fructofuranosidase activity
KMZ16_RS19585	COG1263	PTS System
KMZ16_RS19585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KMZ16_RS19590	COG2116	formate transmembrane transporter activity
KMZ16_RS19595	COG3711	transcriptional antiterminator
KMZ16_RS19605	COG1404	Belongs to the peptidase S8 family
KMZ16_RS19610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMZ16_RS19615	COG0778	Nitroreductase
KMZ16_RS19620	COG0772	Belongs to the SEDS family
KMZ16_RS19630	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KMZ16_RS19635	COG1845	cytochrome c oxidase, subunit III
KMZ16_RS19640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KMZ16_RS19645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KMZ16_RS19650	COG2261	transglycosylase associated protein
KMZ16_RS19655	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KMZ16_RS19660	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KMZ16_RS19665	COG2246	polysaccharide biosynthetic process
KMZ16_RS19670	COG1309	transcriptional regulator
KMZ16_RS19680	COG3162	membrane
KMZ16_RS19685	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMZ16_RS19690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KMZ16_RS19695	COG2837	iron assimilation
KMZ16_RS19700	COG2822	iron ion transport
KMZ16_RS19705	COG0672	)-iron permease
KMZ16_RS19710	COG0352	thiamine-phosphate diphosphorylase activity
KMZ16_RS19715	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KMZ16_RS19720	COG0583	DNA-binding transcription factor activity
KMZ16_RS19725	COG1380	Effector of murein hydrolase LrgA
KMZ16_RS19730	COG1346	cytolysis
KMZ16_RS19735	COG2814	Major facilitator Superfamily
KMZ16_RS19740	COG4895	conserved protein (DUF2196)
KMZ16_RS19745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KMZ16_RS19750	COG0346	lactoylglutathione lyase activity
KMZ16_RS19755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KMZ16_RS19760	COG1404	Belongs to the peptidase S8 family
KMZ16_RS19765	COG1263	PTS System
KMZ16_RS19765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KMZ16_RS19770	COG3711	transcriptional antiterminator
KMZ16_RS19775	COG1442	glycosyl transferase family 8
KMZ16_RS19780	COG5522	Integral membrane protein (intg_mem_TP0381)
KMZ16_RS19785	COG1846	Transcriptional regulator
KMZ16_RS19790	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KMZ16_RS19795	COG2234	aminopeptidase activity
KMZ16_RS19810	COG2814	Major facilitator Superfamily
KMZ16_RS19815	COG2357	RelA SpoT domain protein
KMZ16_RS19820	COG1575	Belongs to the MenA family. Type 1 subfamily
KMZ16_RS19835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KMZ16_RS19840	COG1696	Membrane protein involved in D-alanine export
KMZ16_RS19845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KMZ16_RS19850	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KMZ16_RS19855	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KMZ16_RS19860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KMZ16_RS19865	COG1486	melibiose metabolic process
KMZ16_RS19870	COG1447	Phosphotransferase system cellobiose-specific component IIA
KMZ16_RS19875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KMZ16_RS19880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KMZ16_RS19895	COG2094	Belongs to the DNA glycosylase MPG family
KMZ16_RS19900	COG0753	catalase activity
KMZ16_RS19905	COG2814	Major facilitator Superfamily
KMZ16_RS19910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KMZ16_RS19915	COG1131	(ABC) transporter
KMZ16_RS19935	COG1595	DNA-templated transcription, initiation
KMZ16_RS19940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KMZ16_RS19950	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KMZ16_RS19955	COG4988	ABC transporter
KMZ16_RS19960	COG1294	oxidase, subunit
KMZ16_RS19965	COG1271	oxidase subunit
KMZ16_RS19970	COG3493	citrate carrier protein
KMZ16_RS19975	COG0501	Belongs to the peptidase M48B family
KMZ16_RS19985	COG0726	polysaccharide deacetylase
KMZ16_RS19990	COG3842	ATPase activity
KMZ16_RS19995	COG2508	Transcriptional regulator
KMZ16_RS20000	COG1012	belongs to the aldehyde dehydrogenase family
KMZ16_RS20005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMZ16_RS20015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KMZ16_RS20025	COG4585	Histidine kinase
KMZ16_RS20030	COG2197	response regulator
KMZ16_RS20035	COG2195	Cleaves the N-terminal amino acid of tripeptides
KMZ16_RS20050	COG4894	glucomannan catabolic process
KMZ16_RS20055	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KMZ16_RS20060	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KMZ16_RS20065	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS20070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KMZ16_RS20075	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KMZ16_RS20080	COG2610	gluconate transmembrane transporter activity
KMZ16_RS20085	COG0500	methyltransferase
KMZ16_RS20090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KMZ16_RS20105	COG0753	catalase activity
KMZ16_RS20105	COG0693	protein deglycase activity
KMZ16_RS20110	COG2851	Citrate transporter
KMZ16_RS20115	COG2273	Hydrolase Family 16
KMZ16_RS20120	COG3711	transcriptional antiterminator
KMZ16_RS20130	COG2270	Major facilitator Superfamily
KMZ16_RS20135	COG0513	Belongs to the DEAD box helicase family
KMZ16_RS20140	COG3401	FG-GAP repeat protein
KMZ16_RS20140	COG2755	lipolytic protein G-D-S-L family
KMZ16_RS20165	COG0697	spore germination
KMZ16_RS20170	COG0789	Transcriptional regulator
KMZ16_RS20190	COG0589	response to stress
KMZ16_RS20195	COG2723	6-phospho-beta-galactosidase activity
KMZ16_RS20200	COG1263	PTS System
KMZ16_RS20200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KMZ16_RS20200	COG2190	(PTS) system
KMZ16_RS20250	COG3507	Belongs to the glycosyl hydrolase 43 family
KMZ16_RS20265	COG2986	histidine ammonia-lyase
KMZ16_RS20270	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KMZ16_RS20275	COG1228	amidohydrolase
KMZ16_RS20280	COG0010	Belongs to the arginase family
KMZ16_RS20285	COG0833	amino acid
KMZ16_RS20290	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KMZ16_RS20295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KMZ16_RS20300	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KMZ16_RS20305	COG2390	Transcriptional regulator
KMZ16_RS20315	COG3192	ethanolamine utilization protein
KMZ16_RS20320	COG2079	MmgE PrpD family protein
KMZ16_RS20325	COG1473	amidohydrolase
KMZ16_RS20330	COG1126	abc transporter atp-binding protein
KMZ16_RS20335	COG0765	amino acid transport
KMZ16_RS20340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KMZ16_RS20345	COG0456	acetyltransferase
KMZ16_RS20350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMZ16_RS20355	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KMZ16_RS20360	COG0561	phosphatase activity
KMZ16_RS20390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KMZ16_RS20395	COG5294	Protein conserved in bacteria
KMZ16_RS20400	COG0577	efflux transmembrane transporter activity
KMZ16_RS20405	COG1136	(ABC) transporter
KMZ16_RS20410	COG2205	protein histidine kinase activity
KMZ16_RS20415	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS20420	COG0191	fructose-bisphosphate aldolase activity
KMZ16_RS20425	COG1082	Xylose isomerase domain protein TIM barrel
KMZ16_RS20430	COG1082	Xylose isomerase domain protein TIM barrel
KMZ16_RS20435	COG0673	inositol 2-dehydrogenase activity
KMZ16_RS20440	COG2814	Major facilitator Superfamily
KMZ16_RS20445	COG1082	Xylose isomerase domain protein TIM barrel
KMZ16_RS20450	COG3962	Belongs to the TPP enzyme family
KMZ16_RS20455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KMZ16_RS20465	COG1012	belongs to the aldehyde dehydrogenase family
KMZ16_RS20470	COG1349	DNA-binding transcription factor activity
KMZ16_RS20475	COG0667	Aldo Keto reductase
KMZ16_RS20490	COG2814	Major facilitator Superfamily
KMZ16_RS20495	COG0326	Molecular chaperone. Has ATPase activity
KMZ16_RS20505	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS20510	COG1309	transcriptional regulator
KMZ16_RS20515	COG1012	belongs to the aldehyde dehydrogenase family
KMZ16_RS20525	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KMZ16_RS20535	COG1714	RDD family
KMZ16_RS20540	COG2311	Membrane
KMZ16_RS20545	COG1917	Cupin 2, conserved barrel domain protein
KMZ16_RS20550	COG1309	transcriptional regulator
KMZ16_RS20555	COG1028	Short-chain dehydrogenase reductase Sdr
KMZ16_RS20560	COG1846	Transcriptional regulator
KMZ16_RS20565	COG1380	Effector of murein hydrolase LrgA
KMZ16_RS20570	COG1346	cytolysis
KMZ16_RS20575	COG5039	Polysaccharide pyruvyl transferase
KMZ16_RS20580	COG1929	Belongs to the glycerate kinase type-1 family
KMZ16_RS20585	COG1802	Transcriptional regulator
KMZ16_RS20590	COG1070	Carbohydrate kinase
KMZ16_RS20595	COG2610	gluconate transmembrane transporter activity
KMZ16_RS20600	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KMZ16_RS20605	COG0450	alkyl hydroperoxide reductase
KMZ16_RS20610	COG3634	alkyl hydroperoxide reductase activity
KMZ16_RS20620	COG2723	6-phospho-beta-galactosidase activity
KMZ16_RS20635	COG2188	Transcriptional regulator
KMZ16_RS20650	COG1131	(ABC) transporter
KMZ16_RS20655	COG1994	Peptidase M50
KMZ16_RS20660	COG0535	radical SAM domain protein
KMZ16_RS20670	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
KMZ16_RS20680	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KMZ16_RS20695	COG1063	alcohol dehydrogenase
KMZ16_RS20715	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KMZ16_RS20720	COG0456	acetyltransferase
KMZ16_RS20725	COG0457	Tetratricopeptide repeat
KMZ16_RS20735	COG0010	Belongs to the arginase family
KMZ16_RS20740	COG0833	amino acid
KMZ16_RS20745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KMZ16_RS20750	COG3829	transcription factor binding
KMZ16_RS20755	COG5002	protein histidine kinase activity
KMZ16_RS20760	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS20780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMZ16_RS20785	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KMZ16_RS20790	COG4853	Protein conserved in bacteria
KMZ16_RS20795	COG4863	YycH protein
KMZ16_RS20800	COG5002	protein histidine kinase activity
KMZ16_RS20805	COG0745	RESPONSE REGULATOR receiver
KMZ16_RS20835	COG0346	lactoylglutathione lyase activity
KMZ16_RS20840	COG0305	Participates in initiation and elongation during chromosome replication
KMZ16_RS20855	COG3093	addiction module antidote protein HigA
KMZ16_RS20860	COG2807	transmembrane transport
KMZ16_RS20865	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KMZ16_RS20870	COG0359	binds to the 23S rRNA
KMZ16_RS20875	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KMZ16_RS20880	COG4241	membrane
KMZ16_RS20890	COG5577	PFAM Coat F domain
KMZ16_RS20895	COG1733	regulation of RNA biosynthetic process
KMZ16_RS20900	COG1227	inorganic diphosphatase activity
KMZ16_RS20910	COG2271	Major facilitator Superfamily
KMZ16_RS20915	COG0789	Transcriptional regulator
KMZ16_RS20915	COG4978	Transcriptional regulator
KMZ16_RS20925	COG4319	ketosteroid isomerase
KMZ16_RS20930	COG1357	PFAM Pentapeptide repeats (8 copies)
KMZ16_RS20935	COG2814	Major facilitator Superfamily
KMZ16_RS20940	COG0583	DNA-binding transcription factor activity
KMZ16_RS20945	COG2153	protein acetylation
KMZ16_RS20960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KMZ16_RS20965	COG1846	Transcriptional regulator
KMZ16_RS20970	COG2153	protein acetylation
KMZ16_RS20975	COG2364	Membrane
KMZ16_RS20980	COG0456	acetyltransferase
KMZ16_RS20985	COG2315	Protein conserved in bacteria
KMZ16_RS20990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KMZ16_RS21000	COG2814	Major facilitator Superfamily
KMZ16_RS21025	COG0741	lytic transglycosylase activity
KMZ16_RS21025	COG0791	NLP P60 protein
KMZ16_RS21030	COG5644	endopeptidase inhibitor activity
KMZ16_RS21040	COG0433	COG0433 Predicted ATPase
KMZ16_RS21080	COG1674	ftsk spoiiie
KMZ16_RS21115	COG1396	sequence-specific DNA binding
KMZ16_RS21120	COG2856	Zn peptidase
KMZ16_RS21125	COG0457	Tetratricopeptide repeat
KMZ16_RS21140	COG1331	Highly conserved protein containing a thioredoxin domain
KMZ16_RS21145	COG1331	Highly conserved protein containing a thioredoxin domain
KMZ16_RS21150	COG1266	CAAX protease self-immunity
KMZ16_RS21155	COG0477	Major facilitator Superfamily
KMZ16_RS21155	COG2814	Major facilitator Superfamily
KMZ16_RS21160	COG0110	maltose O-acetyltransferase activity
KMZ16_RS21165	COG0346	lactoylglutathione lyase activity
KMZ16_RS21175	COG0708	Exodeoxyribonuclease III
KMZ16_RS21180	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KMZ16_RS21185	COG0629	single-stranded DNA binding
KMZ16_RS21190	COG0360	Binds together with S18 to 16S ribosomal RNA
KMZ16_RS21195	COG0012	GTP binding
KMZ16_RS21200	COG0243	molybdopterin cofactor binding
KMZ16_RS21205	COG4481	Protein conserved in bacteria
KMZ16_RS21210	COG3949	Membrane
KMZ16_RS21220	COG1475	DNA binding
KMZ16_RS21225	COG1192	Involved in chromosome partitioning
KMZ16_RS21235	COG1475	DNA binding
KMZ16_RS21240	COG0357	Ribosomal RNA small subunit methyltransferase G
KMZ16_RS21245	COG0445	tRNA wobble uridine modification
KMZ16_RS21250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KMZ16_RS21255	COG1847	R3H domain protein
KMZ16_RS21260	COG0706	membrane insertase activity
KMZ16_RS21265	COG0594	ribonuclease P activity