locus-tag	class	description
Q433_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Q433_RS00010	COG0592	DNA-directed DNA polymerase activity
Q433_RS00015	COG2501	S4 domain
Q433_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Q433_RS00030	COG0187	DNA topoisomerase II activity
Q433_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Q433_RS00075	COG1686	Belongs to the peptidase S11 family
Q433_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Q433_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Q433_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Q433_RS00100	COG1428	Deoxynucleoside kinase
Q433_RS00105	COG1428	Deoxynucleoside kinase
Q433_RS00110	COG1388	LysM domain
Q433_RS00110	COG3858	chitin binding
Q433_RS00115	COG1335	isochorismatase
Q433_RS00120	COG0590	tRNA wobble adenosine to inosine editing
Q433_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Q433_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Q433_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Q433_RS00180	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
Q433_RS00185	COG3853	Toxic anion resistance protein (TelA)
Q433_RS00190	COG1982	Orn Lys Arg decarboxylase major
Q433_RS00195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Q433_RS00200	COG3870	Protein conserved in bacteria
Q433_RS00205	COG1728	Protein conserved in bacteria
Q433_RS00210	COG0470	DNA polymerase III
Q433_RS00215	COG1774	PSP1 C-terminal conserved region
Q433_RS00220	COG4467	Involved in initiation control of chromosome replication
Q433_RS00225	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Q433_RS00230	COG2827	Endonuclease containing a URI domain
Q433_RS00235	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Q433_RS00240	COG2002	toxin-antitoxin pair type II binding
Q433_RS00245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q433_RS00245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q433_RS00250	COG0084	hydrolase, TatD family'
Q433_RS00255	COG3584	3D domain protein
Q433_RS00255	COG3583	domain protein
Q433_RS00260	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
Q433_RS00265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Q433_RS00275	COG4466	Protein conserved in bacteria
Q433_RS00285	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Q433_RS00290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Q433_RS00295	COG0251	oxidation-reduction process
Q433_RS00300	COG2088	sporulation resulting in formation of a cellular spore
Q433_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Q433_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Q433_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Q433_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
Q433_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Q433_RS00340	COG2002	toxin-antitoxin pair type II binding
Q433_RS00345	COG2244	polysaccharide biosynthetic process
Q433_RS00350	COG3956	TIGRFAM MazG family protein
Q433_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Q433_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Q433_RS00375	COG1098	S1 RNA binding domain
Q433_RS00390	COG2208	phosphoserine phosphatase activity
Q433_RS00395	COG2304	oxidoreductase activity
Q433_RS00400	COG0515	serine threonine protein kinase
Q433_RS00405	COG0037	tRNA processing
Q433_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q433_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Q433_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Q433_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Q433_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Q433_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Q433_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
Q433_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Q433_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Q433_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Q433_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Q433_RS00470	COG1396	sequence-specific DNA binding
Q433_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Q433_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Q433_RS00565	COG4463	regulation of RNA biosynthetic process
Q433_RS00570	COG3880	PFAM UvrB UvrC protein
Q433_RS00575	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Q433_RS00580	COG0542	response to heat
Q433_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Q433_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Q433_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
Q433_RS00600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Q433_RS00605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Q433_RS00610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Q433_RS00620	COG1045	serine acetyltransferase
Q433_RS00625	COG0215	cysteine-tRNA ligase activity
Q433_RS00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
Q433_RS00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Q433_RS00640	COG3688	RNA-binding protein containing a PIN domain
Q433_RS00645	COG1595	DNA-templated transcription, initiation
Q433_RS00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Q433_RS00660	COG0250	Participates in transcription elongation, termination and antitermination
Q433_RS00670	COG0081	regulation of translation
Q433_RS00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Q433_RS00685	COG2813	Specifically methylates the guanine in position
Q433_RS00690	COG0085	RNA polymerase activity
Q433_RS00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Q433_RS00700	COG1358	cellular component organization or biogenesis
Q433_RS00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Q433_RS00710	COG0049	tRNA binding
Q433_RS00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Q433_RS00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Q433_RS00725	COG0596	Alpha beta hydrolase
Q433_RS00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Q433_RS00740	COG0088	Forms part of the polypeptide exit tunnel
Q433_RS00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Q433_RS00770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Q433_RS00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Q433_RS00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Q433_RS00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Q433_RS00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Q433_RS00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Q433_RS00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Q433_RS00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Q433_RS00830	COG0200	Binds to the 23S rRNA
Q433_RS00835	COG0201	protein transport
Q433_RS00840	COG0563	adenylate kinase activity
Q433_RS00845	COG0024	Methionine aminopeptidase
Q433_RS00850	COG2163	COG2163 Ribosomal protein L14E L6E L27E
Q433_RS00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Q433_RS00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Q433_RS00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Q433_RS00875	COG0202	RNA polymerase activity
Q433_RS00880	COG0203	ribosomal protein L17
Q433_RS00885	COG1122	ATPase activity
Q433_RS00890	COG1122	ATPase activity
Q433_RS00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Q433_RS00900	COG0101	tRNA pseudouridine synthase activity
Q433_RS00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Q433_RS00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q433_RS00915	COG2226	methyltransferase
Q433_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
Q433_RS00940	COG2194	sulfuric ester hydrolase activity
Q433_RS00945	COG0726	polysaccharide deacetylase
Q433_RS00970	COG0659	secondary active sulfate transmembrane transporter activity
Q433_RS00975	COG0385	Bile acid
Q433_RS00980	COG2819	hydrolase of the alpha beta superfamily
Q433_RS00985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_RS00990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_RS00995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Q433_RS01000	COG2207	Transcriptional regulator
Q433_RS01000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Q433_RS01005	COG3876	Protein conserved in bacteria
Q433_RS01010	COG1472	Belongs to the glycosyl hydrolase 3 family
Q433_RS01015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Q433_RS01020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_RS01020	COG1263	PTS System
Q433_RS01025	COG1737	Transcriptional regulator
Q433_RS01030	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Q433_RS01035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_RS01040	COG1683	Conserved Protein
Q433_RS01070	COG1595	DNA-templated transcription, initiation
Q433_RS01075	COG5662	AntiSigma factor
Q433_RS01080	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Q433_RS01085	COG4856	YbbR-like protein
Q433_RS01090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Q433_RS01095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Q433_RS01100	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Q433_RS01105	COG2169	Transcriptional regulator
Q433_RS01110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Q433_RS01115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Q433_RS01120	COG3002	Belongs to the UPF0753 family
Q433_RS01125	COG0288	reversible hydration of carbon dioxide
Q433_RS01135	COG5609	conserved protein (DUF2294)
Q433_RS01145	COG0640	Transcriptional regulator
Q433_RS01150	COG2814	Major facilitator Superfamily
Q433_RS01165	COG1404	Belongs to the peptidase S8 family
Q433_RS01185	COG1132	(ABC) transporter
Q433_RS01190	COG0596	Alpha beta hydrolase
Q433_RS01195	COG0745	RESPONSE REGULATOR receiver
Q433_RS01200	COG0642	Histidine kinase
Q433_RS01210	COG0515	serine threonine protein kinase
Q433_RS01225	COG1113	amino acid transport
Q433_RS01240	COG2602	Beta-lactamase
Q433_RS01245	COG2124	cytochrome p450
Q433_RS01255	COG0531	amino acid
Q433_RS01260	COG0584	glycerophosphoryl diester phosphodiesterase
Q433_RS01265	COG2271	Major facilitator Superfamily
Q433_RS01275	COG0456	acetyltransferase
Q433_RS01275	COG1846	Transcriptional regulator
Q433_RS01280	COG2271	Major facilitator Superfamily
Q433_RS01290	COG3409	Peptidoglycan-binding domain 1 protein
Q433_RS01295	COG0697	spore germination
Q433_RS01300	COG2207	Transcriptional regulator
Q433_RS01300	COG1917	Cupin 2, conserved barrel domain protein
Q433_RS01305	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Q433_RS01310	COG3591	Belongs to the peptidase S1B family
Q433_RS01320	COG0596	Alpha beta hydrolase
Q433_RS01325	COG1183	phosphatidylcholine synthase activity
Q433_RS01330	COG0586	Pfam SNARE associated Golgi protein
Q433_RS01335	COG0688	phosphatidylethanolamine metabolic process
Q433_RS01350	COG1301	dicarboxylic acid transport
Q433_RS01355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_RS01355	COG2190	(PTS) system
Q433_RS01355	COG1263	PTS System
Q433_RS01360	COG0363	glucosamine-6-phosphate deaminase activity
Q433_RS01375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Q433_RS01380	COG0833	amino acid
Q433_RS01385	COG2040	homocysteine
Q433_RS01395	COG1115	amino acid carrier protein
Q433_RS01400	COG2066	Belongs to the glutaminase family
Q433_RS01405	COG4191	Histidine kinase
Q433_RS01410	COG0784	Response regulator, receiver
Q433_RS01415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q433_RS01420	COG1012	belongs to the aldehyde dehydrogenase family
Q433_RS01425	COG2271	Major facilitator Superfamily
Q433_RS01430	COG4948	Mandelate Racemase Muconate Lactonizing
Q433_RS01435	COG2186	Transcriptional regulator
Q433_RS01440	COG2721	sulfolactate sulfo-lyase activity
Q433_RS01445	COG3173	Aminoglycoside phosphotransferase
Q433_RS01455	COG0697	spore germination
Q433_RS01460	COG0745	RESPONSE REGULATOR receiver
Q433_RS01465	COG2205	protein histidine kinase activity
Q433_RS01470	COG1131	(ABC) transporter
Q433_RS01490	COG3773	Cell wall hydrolase
Q433_RS01495	COG2304	oxidoreductase activity
Q433_RS01505	COG3540	Alkaline phosphatase
Q433_RS01510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Q433_RS01515	COG0805	protein transport
Q433_RS01520	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Q433_RS01525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Q433_RS01530	COG0477	Major facilitator Superfamily
Q433_RS01535	COG1309	transcriptional regulator
Q433_RS01540	COG0252	asparaginase activity
Q433_RS01545	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
Q433_RS01550	COG1714	RDD family
Q433_RS01555	COG1405	negative regulation of cell septum assembly
Q433_RS01555	COG3012	SEC-C Motif Domain Protein
Q433_RS01560	COG3290	protein histidine kinase activity
Q433_RS01565	COG3279	Response regulator of the LytR AlgR family
Q433_RS01570	COG4555	ABC transporter
Q433_RS01575	COG1668	transmembrane transport
Q433_RS01580	COG0667	Aldo Keto reductase
Q433_RS01590	COG1595	DNA-templated transcription, initiation
Q433_RS01595	COG1595	DNA-templated transcription, initiation
Q433_RS01600	COG1876	peptidase activity
Q433_RS01605	COG0457	Tetratricopeptide repeat
Q433_RS01610	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS01615	COG0366	Alpha amylase catalytic
Q433_RS01620	COG0803	Belongs to the bacterial solute-binding protein 9 family
Q433_RS01625	COG1121	(ABC) transporter
Q433_RS01630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Q433_RS01635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Q433_RS01640	COG2310	stress, protein
Q433_RS01645	COG2310	stress, protein
Q433_RS01650	COG2310	stress, protein
Q433_RS01655	COG0861	Integral membrane protein TerC family
Q433_RS01665	COG3853	Toxic anion resistance protein (TelA)
Q433_RS01670	COG0477	Major facilitator Superfamily
Q433_RS01675	COG2814	Major facilitator Superfamily
Q433_RS01680	COG0640	Transcriptional regulator
Q433_RS01685	COG0517	IMP dehydrogenase activity
Q433_RS01685	COG4175	Glycine betaine
Q433_RS01690	COG4176	ABC-type proline glycine betaine transport system permease component
Q433_RS01695	COG2113	Glycine betaine
Q433_RS01700	COG1473	amidohydrolase
Q433_RS01705	COG1288	antiporter activity
Q433_RS01720	COG0366	Alpha amylase catalytic
Q433_RS01725	COG0039	L-malate dehydrogenase activity
Q433_RS01730	COG1620	l-lactate permease
Q433_RS01735	COG2814	Major facilitator Superfamily
Q433_RS01740	COG1846	Transcriptional regulator
Q433_RS01745	COG1280	lysine exporter protein (LysE YggA)
Q433_RS01750	COG3403	YqcI/YcgG family
Q433_RS01755	COG1113	amino acid transport
Q433_RS01760	COG3665	Urea carboxylase-associated protein
Q433_RS01765	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Q433_RS01770	COG1660	Displays ATPase and GTPase activities
Q433_RS01775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Q433_RS01780	COG2226	methyltransferase
Q433_RS01785	COG0583	DNA-binding transcription factor activity
Q433_RS01790	COG3458	cephalosporin-C deacetylase activity
Q433_RS01795	COG3541	Predicted nucleotidyltransferase
Q433_RS01800	COG0506	proline dehydrogenase activity
Q433_RS01805	COG1012	belongs to the aldehyde dehydrogenase family
Q433_RS01810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q433_RS01815	COG2508	Transcriptional regulator
Q433_RS01825	COG0701	Predicted permease
Q433_RS01830	COG2267	carboxylic ester hydrolase activity
Q433_RS01835	COG0492	ferredoxin-NADP+ reductase activity
Q433_RS01840	COG1587	Uroporphyrinogen-III synthase
Q433_RS01840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Q433_RS01845	COG2146	nitrite reductase [NAD(P)H] activity
Q433_RS01850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Q433_RS01855	COG0243	molybdopterin cofactor binding
Q433_RS01860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Q433_RS01865	COG2223	nitrite transmembrane transporter activity
Q433_RS01870	COG1469	GTP cyclohydrolase I activity
Q433_RS01875	COG1376	ErfK ybiS ycfS ynhG family protein
Q433_RS01885	COG0523	cobalamin synthesis protein
Q433_RS01890	COG0765	amino acid transport
Q433_RS01895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_RS01905	COG1714	RDD family
Q433_RS01915	COG2723	6-phospho-beta-galactosidase activity
Q433_RS01925	COG3209	COG3209 Rhs family protein
Q433_RS01930	COG3290	protein histidine kinase activity
Q433_RS01930	COG0840	transmembrane signaling receptor activity
Q433_RS01935	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Q433_RS01940	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Q433_RS01945	COG1733	regulation of RNA biosynthetic process
Q433_RS01955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_RS01960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_RS01965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_RS01970	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
Q433_RS01975	COG2814	Major facilitator Superfamily
Q433_RS01985	COG0697	spore germination
Q433_RS02000	COG2364	Membrane
Q433_RS02005	COG1126	abc transporter atp-binding protein
Q433_RS02010	COG0765	amino acid transport
Q433_RS02015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_RS02020	COG0583	DNA-binding transcription factor activity
Q433_RS02025	COG0163	prenyltransferase activity
Q433_RS02030	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Q433_RS02045	COG0596	Alpha beta hydrolase
Q433_RS02050	COG3104	oligopeptide transport
Q433_RS02055	COG5434	Belongs to the glycosyl hydrolase 28 family
Q433_RS02065	COG0697	spore germination
Q433_RS02075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Q433_RS02080	COG1136	(ABC) transporter
Q433_RS02085	COG0577	efflux transmembrane transporter activity
Q433_RS02090	COG0745	RESPONSE REGULATOR receiver
Q433_RS02095	COG3850	Histidine kinase
Q433_RS02095	COG5002	protein histidine kinase activity
Q433_RS02100	COG0457	Tetratricopeptide repeat
Q433_RS02120	COG0527	aspartate kinase activity
Q433_RS02125	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_RS02130	COG4605	iron ion homeostasis
Q433_RS02135	COG4604	ABC transporter, ATP-binding protein
Q433_RS02140	COG4607	ABC-type enterochelin transport system periplasmic component
Q433_RS02145	COG2814	Major facilitator Superfamily
Q433_RS02150	COG1309	transcriptional regulator
Q433_RS02155	COG0778	Nitroreductase
Q433_RS02160	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Q433_RS02165	COG0640	Transcriptional regulator
Q433_RS02170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q433_RS02175	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Q433_RS02180	COG1012	belongs to the aldehyde dehydrogenase family
Q433_RS02185	COG4975	Glucose uptake
Q433_RS02190	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS02195	COG4549	nuclear export factor GLE1
Q433_RS02200	COG2372	response to copper ion
Q433_RS02200	COG1276	copper resistance
Q433_RS02205	COG1349	DNA-binding transcription factor activity
Q433_RS02215	COG2213	PTS system mannitol-specific
Q433_RS02220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_RS02225	COG0246	Mannitol dehydrogenase
Q433_RS02230	COG0473	3-isopropylmalate dehydrogenase activity
Q433_RS02235	COG0681	Belongs to the peptidase S26 family
Q433_RS02245	COG0412	Dienelactone hydrolase
Q433_RS02250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Q433_RS02260	COG0561	phosphatase activity
Q433_RS02265	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Q433_RS02270	COG1914	H( )-stimulated, divalent metal cation uptake system
Q433_RS02280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Q433_RS02285	COG1984	allophanate hydrolase subunit 2
Q433_RS02290	COG1414	Transcriptional regulator
Q433_RS02295	COG2755	lipolytic protein G-D-S-L family
Q433_RS02305	COG2329	Antibiotic biosynthesis monooxygenase
Q433_RS02310	COG0768	penicillin binding
Q433_RS02315	COG4989	oxidoreductase activity
Q433_RS02320	COG3711	transcriptional antiterminator
Q433_RS02325	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_RS02330	COG2226	methyltransferase
Q433_RS02335	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS02340	COG1917	Cupin 2, conserved barrel domain protein
Q433_RS02345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_RS02350	COG3871	stress protein (general stress protein 26)
Q433_RS02360	COG2814	Major facilitator Superfamily
Q433_RS02365	COG1522	sequence-specific DNA binding
Q433_RS02370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Q433_RS02370	COG0551	DNA topoisomerase type I activity
Q433_RS02375	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Q433_RS02380	COG3706	GGDEF domain
Q433_RS02385	COG5298	Protein conserved in bacteria
Q433_RS02390	COG1215	transferase activity, transferring glycosyl groups
Q433_RS02400	COG0531	amino acid
Q433_RS02405	COG0494	nUDIX hydrolase
Q433_RS02410	COG0028	Belongs to the TPP enzyme family
Q433_RS02425	COG1914	H( )-stimulated, divalent metal cation uptake system
Q433_RS02430	COG2261	transglycosylase associated protein
Q433_RS02435	COG4876	unkown
Q433_RS02440	COG2217	Heavy metal translocating P-type atpase
Q433_RS02445	COG3729	General stress protein
Q433_RS02450	COG0662	Cupin 2, conserved barrel domain protein
Q433_RS02455	COG2329	Antibiotic biosynthesis monooxygenase
Q433_RS02460	COG3546	catalase activity
Q433_RS02465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Q433_RS02470	COG3290	protein histidine kinase activity
Q433_RS02475	COG4565	transcriptional regulatory protein
Q433_RS02480	COG1301	dicarboxylic acid transport
Q433_RS02485	COG0628	permease
Q433_RS02495	COG1131	(ABC) transporter
Q433_RS02500	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Q433_RS02510	COG1960	acyl-CoA dehydrogenase activity
Q433_RS02525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Q433_RS02530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_RS02535	COG1181	Belongs to the D-alanine--D-alanine ligase family
Q433_RS02540	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Q433_RS02545	COG0513	Belongs to the DEAD box helicase family
Q433_RS02550	COG3402	PFAM membrane-flanked domain
Q433_RS02555	COG3428	Bacterial PH domain
Q433_RS02560	COG0705	Rhomboid family
Q433_RS02565	COG0736	holo-[acyl-carrier-protein] synthase activity
Q433_RS02570	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Q433_RS02575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Q433_RS02580	COG0864	Transcriptional regulator
Q433_RS02585	COG2337	Toxic component of a toxin-antitoxin (TA) module
Q433_RS02590	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_RS02595	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_RS02600	COG2172	sigma factor antagonist activity
Q433_RS02605	COG2208	phosphoserine phosphatase activity
Q433_RS02610	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_RS02615	COG2172	sigma factor antagonist activity
Q433_RS02620	COG1191	sigma factor activity
Q433_RS02625	COG2208	phosphoserine phosphatase activity
Q433_RS02630	COG2183	response to ionizing radiation
Q433_RS02640	COG3091	SprT-like family
Q433_RS02690	COG1476	TRANSCRIPTIONal
Q433_RS02715	COG0693	protein deglycase activity
Q433_RS02720	COG1278	Cold shock
Q433_RS02730	COG0697	spore germination
Q433_RS02735	COG1917	Cupin 2, conserved barrel domain protein
Q433_RS02735	COG2207	Transcriptional regulator
Q433_RS02740	COG0697	spore germination
Q433_RS02750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q433_RS02755	COG0477	Major facilitator Superfamily
Q433_RS02765	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
Q433_RS02775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_RS02780	COG1309	transcriptional regulator
Q433_RS02785	COG0697	spore germination
Q433_RS02790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q433_RS02795	COG2030	dehydratase
Q433_RS02800	COG3545	Serine hydrolase
Q433_RS02805	COG1733	regulation of RNA biosynthetic process
Q433_RS02810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_RS02815	COG2814	Major facilitator Superfamily
Q433_RS02820	COG1309	transcriptional regulator
Q433_RS02830	COG0640	Transcriptional regulator
Q433_RS02835	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Q433_RS02845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_RS02850	COG0697	spore germination
Q433_RS02855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q433_RS02860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Q433_RS02865	COG0640	Transcriptional regulator
Q433_RS02870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Q433_RS02885	COG4585	Histidine kinase
Q433_RS02890	COG2197	response regulator
Q433_RS02895	COG2409	Drug exporters of the RND superfamily
Q433_RS02900	COG0596	Alpha beta hydrolase
Q433_RS02905	COG1811	Na channel or pump
Q433_RS02910	COG4978	Transcriptional regulator
Q433_RS02910	COG0789	Transcriptional regulator
Q433_RS02915	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Q433_RS02920	COG0778	Nitroreductase
Q433_RS02925	COG0346	lactoylglutathione lyase activity
Q433_RS02930	COG2259	Doxx family
Q433_RS02935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_RS02955	COG2323	membrane
Q433_RS02960	COG2323	membrane
Q433_RS02965	COG0071	Belongs to the small heat shock protein (HSP20) family
Q433_RS02980	COG1309	transcriptional regulator
Q433_RS02990	COG0456	acetyltransferase
Q433_RS03000	COG1113	amino acid transport
Q433_RS03005	COG2318	DinB family
Q433_RS03010	COG1846	Transcriptional regulator
Q433_RS03015	COG1033	growth of symbiont in host cell
Q433_RS03015	COG2409	Drug exporters of the RND superfamily
Q433_RS03020	COG0778	Nitroreductase
Q433_RS03025	COG1846	Transcriptional regulator
Q433_RS03030	COG2814	Major facilitator Superfamily
Q433_RS03035	COG0730	response to heat
Q433_RS03040	COG1802	Transcriptional regulator
Q433_RS03045	COG3858	chitin binding
Q433_RS03045	COG1388	LysM domain
Q433_RS03050	COG1819	glycosyl
Q433_RS03060	COG1785	Belongs to the alkaline phosphatase family
Q433_RS03065	COG5646	InterPro IPR014922
Q433_RS03075	COG0454	-acetyltransferase
Q433_RS03080	COG1078	dGTPase activity
Q433_RS03085	COG1388	LysM domain
Q433_RS03090	COG2814	Major facilitator Superfamily
Q433_RS03095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Q433_RS03100	COG1447	Phosphotransferase system cellobiose-specific component IIA
Q433_RS03105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Q433_RS03110	COG2723	6-phospho-beta-galactosidase activity
Q433_RS03115	COG2188	Transcriptional regulator
Q433_RS03120	COG1940	carbohydrate kinase activity
Q433_RS03125	COG1482	cell wall glycoprotein biosynthetic process
Q433_RS03130	COG4124	Belongs to the glycosyl hydrolase 26 family
Q433_RS03175	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Q433_RS03180	COG0802	atpase or kinase
Q433_RS03185	COG1214	PFAM Peptidase M22, glycoprotease
Q433_RS03190	COG0456	acetyltransferase
Q433_RS03195	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Q433_RS03200	COG0488	(ABC) transporter
Q433_RS03205	COG0315	cyclic pyranopterin monophosphate synthase activity
Q433_RS03210	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Q433_RS03215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Q433_RS03220	COG0805	protein transport
Q433_RS03230	COG1266	CAAX protease self-immunity
Q433_RS03240	COG0459	protein refolding
Q433_RS03250	COG0457	Tetratricopeptide repeat
Q433_RS03255	COG1063	alcohol dehydrogenase
Q433_RS03260	COG2211	Major facilitator Superfamily
Q433_RS03265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q433_RS03270	COG1842	Phage shock protein A
Q433_RS03275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Q433_RS03280	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Q433_RS03285	COG4260	virion core protein, lumpy skin disease virus
Q433_RS03295	COG2814	Major facilitator Superfamily
Q433_RS03300	COG1063	alcohol dehydrogenase
Q433_RS03305	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Q433_RS03310	COG0823	Involved in the tonB-independent uptake of proteins
Q433_RS03325	COG2267	carboxylic ester hydrolase activity
Q433_RS03335	COG2132	Multicopper oxidase
Q433_RS03340	COG1113	amino acid transport
Q433_RS03350	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Q433_RS03355	COG0714	Associated with various cellular activities
Q433_RS03360	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
Q433_RS03365	COG1305	Transglutaminase-like
Q433_RS03370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Q433_RS03370	COG0519	Catalyzes the synthesis of GMP from XMP
Q433_RS03375	COG2252	PERMEase
Q433_RS03380	COG3064	Membrane
Q433_RS03390	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Q433_RS03400	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Q433_RS03405	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Q433_RS03410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Q433_RS03415	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Q433_RS03420	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Q433_RS03425	COG0047	phosphoribosylformylglycinamidine synthase activity
Q433_RS03430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Q433_RS03435	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Q433_RS03440	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Q433_RS03445	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Q433_RS03450	COG0138	bifunctional purine biosynthesis protein purh
Q433_RS03455	COG0151	Belongs to the GarS family
Q433_RS03460	COG1522	sequence-specific DNA binding
Q433_RS03465	COG0531	amino acid
Q433_RS03475	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Q433_RS03480	COG1470	cell adhesion involved in biofilm formation
Q433_RS03485	COG4496	protein, YerC YecD
Q433_RS03490	COG0069	glutamate synthase activity
Q433_RS03495	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
Q433_RS03500	COG0210	DNA helicase
Q433_RS03505	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Q433_RS03510	COG4851	CamS sex pheromone cAM373 precursor
Q433_RS03515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Q433_RS03520	COG1285	pathogenesis
Q433_RS03525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q433_RS03530	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Q433_RS03535	COG0154	amidase activity
Q433_RS03540	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Q433_RS03545	COG1309	transcriptional regulator
Q433_RS03550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Q433_RS03555	COG1597	lipid kinase activity
Q433_RS03560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Q433_RS03570	COG0457	Tetratricopeptide repeat
Q433_RS03585	COG5444	nuclease activity
Q433_RS03590	COG3391	amine dehydrogenase activity
Q433_RS03595	COG0457	Tetratricopeptide repeat
Q433_RS03605	COG0217	transcriptional regulatory protein
Q433_RS03615	COG1309	transcriptional regulator
Q433_RS03620	COG3631	Ketosteroid isomerase-related protein
Q433_RS03625	COG0702	epimerase
Q433_RS03640	COG3546	catalase activity
Q433_RS03645	COG0454	-acetyltransferase
Q433_RS03655	COG5578	integral membrane protein
Q433_RS03660	COG2972	Histidine kinase
Q433_RS03665	COG2207	Transcriptional regulator
Q433_RS03665	COG4753	response regulator
Q433_RS03670	COG1653	transport
Q433_RS03675	COG1175	transmembrane transport
Q433_RS03680	COG0395	ABC-type sugar transport system, permease component
Q433_RS03685	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Q433_RS03690	COG2207	Transcriptional regulator
Q433_RS03695	COG2755	lipolytic protein G-D-S-L family
Q433_RS03705	COG5578	integral membrane protein
Q433_RS03710	COG3401	FG-GAP repeat protein
Q433_RS03715	COG3401	FG-GAP repeat protein
Q433_RS03720	COG2755	lipolytic protein G-D-S-L family
Q433_RS03725	COG1874	Beta-galactosidase
Q433_RS03735	COG1653	transport
Q433_RS03740	COG4209	transmembrane transport
Q433_RS03745	COG0395	ABC-type sugar transport system, permease component
Q433_RS03750	COG1486	melibiose metabolic process
Q433_RS03755	COG2323	membrane
Q433_RS03760	COG2329	Antibiotic biosynthesis monooxygenase
Q433_RS03765	COG0346	lactoylglutathione lyase activity
Q433_RS03780	COG5583	Uncharacterized small protein (DUF2292)
Q433_RS03785	COG0670	Belongs to the BI1 family
Q433_RS03790	COG0697	spore germination
Q433_RS03795	COG1846	Transcriptional regulator
Q433_RS03800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Q433_RS03815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Q433_RS03815	COG2124	cytochrome p450
Q433_RS03820	COG1368	sulfuric ester hydrolase activity
Q433_RS03825	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Q433_RS03830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q433_RS03835	COG1442	glycosyl transferase family 8
Q433_RS03840	COG1216	Glycosyl transferase, family 2
Q433_RS03845	COG1442	glycosyl transferase family 8
Q433_RS03850	COG2223	nitrite transmembrane transporter activity
Q433_RS03855	COG1011	Hydrolase
Q433_RS03860	COG0531	amino acid
Q433_RS03865	COG1012	belongs to the aldehyde dehydrogenase family
Q433_RS03870	COG0840	transmembrane signaling receptor activity
Q433_RS03875	COG0488	(ABC) transporter
Q433_RS03885	COG0789	Transcriptional regulator
Q433_RS03890	COG2814	Major facilitator Superfamily
Q433_RS03910	COG0488	(ABC) transporter
Q433_RS03915	COG0513	Belongs to the DEAD box helicase family
Q433_RS03920	COG0456	acetyltransferase
Q433_RS03925	COG2130	NADP-dependent
Q433_RS03940	COG2211	Major facilitator Superfamily
Q433_RS03945	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Q433_RS03950	COG1120	ATPase activity
Q433_RS03955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_RS03960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_RS03965	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Q433_RS03980	COG3866	Pectate lyase
Q433_RS03985	COG0471	metal ion transport
Q433_RS03990	COG3290	protein histidine kinase activity
Q433_RS03995	COG4565	transcriptional regulatory protein
Q433_RS04000	COG3181	Tripartite tricarboxylate transporter family receptor
Q433_RS04010	COG2851	Citrate transporter
Q433_RS04015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_RS04020	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
Q433_RS04025	COG1254	Belongs to the acylphosphatase family
Q433_RS04030	COG2258	MOSC domain
Q433_RS04050	COG0024	Methionine aminopeptidase
Q433_RS04055	COG1263	PTS System
Q433_RS04055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_RS04060	COG1368	sulfuric ester hydrolase activity
Q433_RS04070	COG1115	amino acid carrier protein
Q433_RS04075	COG0531	amino acid
Q433_RS04090	COG0697	spore germination
Q433_RS04095	COG1263	PTS System
Q433_RS04095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_RS04100	COG0366	Alpha amylase catalytic
Q433_RS04105	COG2188	Transcriptional regulator
Q433_RS04110	COG0778	Nitroreductase
Q433_RS04115	COG0737	Belongs to the 5'-nucleotidase family
Q433_RS04120	COG0693	protein deglycase activity
Q433_RS04125	COG2814	Major facilitator Superfamily
Q433_RS04130	COG4840	Belongs to the UPF0435 family
Q433_RS04135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Q433_RS04140	COG4980	gas vesicle protein
Q433_RS04145	COG1295	ribonuclease BN
Q433_RS04155	COG0477	Major facilitator Superfamily
Q433_RS04165	COG0387	Pfam Sodium calcium exchanger
Q433_RS04175	COG0668	transmembrane transport
Q433_RS04180	COG0535	radical SAM domain protein
Q433_RS04190	COG0726	polysaccharide deacetylase
Q433_RS04195	COG2084	Dehydrogenase
Q433_RS04200	COG0598	Magnesium transport protein CorA
Q433_RS04205	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Q433_RS04210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Q433_RS04220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Q433_RS04225	COG4637	Psort location Cytoplasmic, score
Q433_RS04230	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Q433_RS04235	COG0022	dehydrogenase e1 component
Q433_RS04240	COG0508	dehydrogenase complex catalyzes the overall conversion of
Q433_RS04245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q433_RS04250	COG3284	Transcriptional regulator
Q433_RS04260	COG1742	UPF0060 membrane protein
Q433_RS04280	COG4842	Belongs to the WXG100 family
Q433_RS04285	COG1486	melibiose metabolic process
Q433_RS04290	COG1737	Transcriptional regulator
Q433_RS04295	COG1263	PTS System
Q433_RS04295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_RS04300	COG5434	Belongs to the glycosyl hydrolase 28 family
Q433_RS04305	COG1132	(ABC) transporter
Q433_RS04310	COG1132	(ABC) transporter
Q433_RS04315	COG2259	Doxx family
Q433_RS04320	COG2514	catechol 2,3-dioxygenase activity
Q433_RS04325	COG4585	Histidine kinase
Q433_RS04330	COG2197	response regulator
Q433_RS04335	COG1131	(ABC) transporter
Q433_RS04340	COG1511	domain protein
Q433_RS04340	COG0842	Transport permease protein
Q433_RS04345	COG0842	Transport permease protein
Q433_RS04350	COG1695	Transcriptional regulator
Q433_RS04355	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
Q433_RS04360	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
Q433_RS04365	COG2318	DinB family
Q433_RS04370	COG2814	Major facilitator Superfamily
Q433_RS04375	COG1846	Transcriptional regulator
Q433_RS04380	COG0392	lysyltransferase activity
Q433_RS04380	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Q433_RS04385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Q433_RS04390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_RS04395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_RS04400	COG0384	phenazine biosynthesis protein PhzF
Q433_RS04405	COG0778	Nitroreductase
Q433_RS04420	COG1090	epimerase
Q433_RS04425	COG2137	regulation of response to DNA damage stimulus
Q433_RS04440	COG2814	Major facilitator Superfamily
Q433_RS04455	COG3103	Sh3 type 3 domain protein
Q433_RS04460	COG5658	integral membrane protein
Q433_RS04465	COG0596	Alpha beta hydrolase
Q433_RS04475	COG4485	Bacterial membrane protein, YfhO
Q433_RS04480	COG1988	membrane-bound metal-dependent
Q433_RS04485	COG1194	a g-specific adenine glycosylase
Q433_RS04495	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS04510	COG3557	Belongs to the UPF0374 family
Q433_RS04515	COG1132	(ABC) transporter
Q433_RS04520	COG4129	membrane
Q433_RS04525	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Q433_RS04530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Q433_RS04535	COG0735	belongs to the Fur family
Q433_RS04650	COG4326	sporulation control protein
Q433_RS04665	COG3340	Belongs to the peptidase S51 family
Q433_RS04670	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Q433_RS04675	COG0277	FAD linked oxidase domain protein
Q433_RS04685	COG0753	catalase activity
Q433_RS04690	COG1116	anion transmembrane transporter activity
Q433_RS04695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Q433_RS04700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q433_RS04705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Q433_RS04715	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Q433_RS04725	COG1476	TRANSCRIPTIONal
Q433_RS04735	COG3382	B3 4 domain protein
Q433_RS04740	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Q433_RS04750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Q433_RS04755	COG0789	Transcriptional regulator
Q433_RS04760	COG1664	Polymer-forming cytoskeletal
Q433_RS04765	COG1664	Polymer-forming cytoskeletal
Q433_RS04770	COG2766	serine protein kinase
Q433_RS04775	COG2718	Belongs to the UPF0229 family
Q433_RS04785	COG1846	Transcriptional regulator
Q433_RS04790	COG1566	PFAM secretion protein HlyD family protein
Q433_RS04795	COG2814	Major facilitator Superfamily
Q433_RS04800	COG0655	NAD(P)H dehydrogenase (quinone) activity
Q433_RS04815	COG1725	Transcriptional regulator
Q433_RS04820	COG1131	(ABC) transporter
Q433_RS04825	COG1131	(ABC) transporter
Q433_RS04830	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Q433_RS04835	COG1278	Cold shock
Q433_RS04845	COG1464	Belongs to the NlpA lipoprotein family
Q433_RS04850	COG3706	GGDEF domain
Q433_RS04855	COG1823	symporter activity
Q433_RS04875	COG5577	PFAM Coat F domain
Q433_RS04880	COG1525	nuclease
Q433_RS04880	COG0737	Belongs to the 5'-nucleotidase family
Q433_RS04880	COG4085	toxin activity
Q433_RS04885	COG3764	Sortase (surface protein transpeptidase)
Q433_RS04890	COG0564	pseudouridine synthase activity
Q433_RS04900	COG0517	IMP dehydrogenase activity
Q433_RS04905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Q433_RS04910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Q433_RS04910	COG3153	acetyltransferase
Q433_RS04915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Q433_RS04920	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
Q433_RS04925	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Q433_RS04930	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Q433_RS04935	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Q433_RS04940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Q433_RS04945	COG2203	Gaf domain
Q433_RS04945	COG4585	Histidine kinase
Q433_RS04950	COG2197	response regulator
Q433_RS04955	COG0431	NADPH-dependent FMN reductase
Q433_RS04970	COG1388	LysM domain
Q433_RS04970	COG0791	NLP P60 protein
Q433_RS04975	COG1959	2 iron, 2 sulfur cluster binding
Q433_RS04980	COG0668	transmembrane transport
Q433_RS04985	COG2719	SpoVR family
Q433_RS04990	COG1785	Belongs to the alkaline phosphatase family
Q433_RS04995	COG0791	NLP P60 protein
Q433_RS04995	COG1388	LysM domain
Q433_RS05000	COG0583	DNA-binding transcription factor activity
Q433_RS05005	COG0372	Belongs to the citrate synthase family
Q433_RS05010	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS05015	COG0531	amino acid
Q433_RS05020	COG0733	neurotransmitter:sodium symporter activity
Q433_RS05025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q433_RS05045	COG1595	DNA-templated transcription, initiation
Q433_RS05050	COG0667	Aldo Keto reductase
Q433_RS05055	COG0204	Acyl-transferase
Q433_RS05060	COG1253	flavin adenine dinucleotide binding
Q433_RS05065	COG0789	Transcriptional regulator
Q433_RS05070	COG0436	Aminotransferase
Q433_RS05075	COG1253	flavin adenine dinucleotide binding
Q433_RS05080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Q433_RS05085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Q433_RS05090	COG0584	glycerophosphoryl diester phosphodiesterase
Q433_RS05100	COG0668	transmembrane transport
Q433_RS05105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Q433_RS05110	COG0726	polysaccharide deacetylase
Q433_RS05115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Q433_RS05120	COG1757	Na H antiporter
Q433_RS05125	COG0589	response to stress
Q433_RS05135	COG1132	(ABC) transporter
Q433_RS05140	COG1132	(ABC) transporter
Q433_RS05145	COG0702	epimerase
Q433_RS05160	COG0189	ligase activity
Q433_RS05165	COG0189	ligase activity
Q433_RS05170	COG4399	Belongs to the UPF0754 family
Q433_RS05175	COG3679	Belongs to the UPF0342 family
Q433_RS05180	COG4335	DNA alkylation repair
Q433_RS05185	COG0561	phosphatase activity
Q433_RS05190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Q433_RS05195	COG0475	glutathione-regulated potassium exporter activity
Q433_RS05200	COG0490	domain, Protein
Q433_RS05210	COG1024	Enoyl-CoA hydratase
Q433_RS05220	COG4152	abc transporter atp-binding protein
Q433_RS05225	COG1668	transmembrane transport
Q433_RS05230	COG0420	3'-5' exonuclease activity
Q433_RS05235	COG4717	serine-type aminopeptidase activity
Q433_RS05240	COG3481	metal-dependent phosphohydrolase, HD sub domain
Q433_RS05250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Q433_RS05275	COG1846	Transcriptional regulator
Q433_RS05280	COG4980	gas vesicle protein
Q433_RS05295	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Q433_RS05300	COG0537	adenosine 5'-monophosphoramidase activity
Q433_RS05305	COG1131	(ABC) transporter
Q433_RS05310	COG4473	ABC transporter
Q433_RS05320	COG1473	amidohydrolase
Q433_RS05325	COG3069	C4-dicarboxylate transmembrane transporter activity
Q433_RS05335	COG2329	Antibiotic biosynthesis monooxygenase
Q433_RS05340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Q433_RS05345	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Q433_RS05360	COG1309	transcriptional regulator
Q433_RS05365	COG1511	domain protein
Q433_RS05370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q433_RS05375	COG4377	Putative membrane peptidase family (DUF2324)
Q433_RS05385	COG1363	Peptidase, m42
Q433_RS05390	COG4405	Protein conserved in bacteria
Q433_RS05395	COG1301	dicarboxylic acid transport
Q433_RS05405	COG1234	tRNA 3'-trailer cleavage
Q433_RS05410	COG0095	Lipoate-protein ligase
Q433_RS05415	COG0702	epimerase
Q433_RS05420	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_RS05430	COG0501	Belongs to the peptidase M48B family
Q433_RS05435	COG1404	Belongs to the peptidase S8 family
Q433_RS05445	COG0604	alcohol dehydrogenase
Q433_RS05450	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Q433_RS05455	COG0406	alpha-ribazole phosphatase activity
Q433_RS05460	COG0183	Belongs to the thiolase family
Q433_RS05465	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_RS05470	COG1268	BioY protein
Q433_RS05475	COG0840	transmembrane signaling receptor activity
Q433_RS05480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q433_RS05480	COG0723	plastoquinol--plastocyanin reductase activity
Q433_RS05485	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS05495	COG4903	ComK protein
Q433_RS05500	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS05510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q433_RS05525	COG0398	Pfam SNARE associated Golgi protein
Q433_RS05530	COG0681	Belongs to the peptidase S26 family
Q433_RS05535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Q433_RS05540	COG1846	Transcriptional regulator
Q433_RS05545	COG0738	Major facilitator superfamily
Q433_RS05550	COG0673	inositol 2-dehydrogenase activity
Q433_RS05555	COG0561	phosphatase activity
Q433_RS05560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Q433_RS05565	COG1609	Transcriptional regulator
Q433_RS05570	COG3180	Ammonia monooxygenase
Q433_RS05575	COG2814	Major facilitator Superfamily
Q433_RS05575	COG0477	Major facilitator Superfamily
Q433_RS05580	COG4533	DNA binding
Q433_RS05590	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
Q433_RS05595	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Q433_RS05600	COG1074	ATP-dependent DNA helicase activity
Q433_RS05605	COG0420	3'-5' exonuclease activity
Q433_RS05610	COG0419	ATPase involved in DNA repair
Q433_RS05615	COG1403	HNH endonuclease
Q433_RS05660	COG5337	Spore coat protein CotH
Q433_RS05665	COG0179	Fumarylacetoacetate (FAA) hydrolase
Q433_RS05675	COG1404	Belongs to the peptidase S8 family
Q433_RS05685	COG0367	asparagine synthase
Q433_RS05690	COG2318	DinB family
Q433_RS05695	COG1562	ergosterol biosynthetic process
Q433_RS05700	COG0534	Mate efflux family protein
Q433_RS05705	COG1917	Cupin 2, conserved barrel domain protein
Q433_RS05705	COG2207	Transcriptional regulator
Q433_RS05710	COG1609	Transcriptional regulator
Q433_RS05715	COG0673	inositol 2-dehydrogenase activity
Q433_RS05720	COG2318	DinB family
Q433_RS05725	COG1279	arginine transmembrane transporter activity
Q433_RS05730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q433_RS05735	COG1357	PFAM Pentapeptide repeats (8 copies)
Q433_RS05740	COG2267	carboxylic ester hydrolase activity
Q433_RS05745	COG0529	Catalyzes the synthesis of activated sulfate
Q433_RS05750	COG2046	Belongs to the sulfate adenylyltransferase family
Q433_RS05755	COG0175	sulfate reduction
Q433_RS05760	COG2045	Belongs to the ComB family
Q433_RS05765	COG1809	phosphosulfolactate synthase activity
Q433_RS05770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_RS05775	COG4948	Mandelate Racemase Muconate Lactonizing
Q433_RS05780	COG2814	Major facilitator Superfamily
Q433_RS05785	COG0454	-acetyltransferase
Q433_RS05790	COG2153	protein acetylation
Q433_RS05795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Q433_RS05795	COG0646	methionine synthase
Q433_RS05800	COG1666	GTP binding
Q433_RS05805	COG2996	Protein conserved in bacteria
Q433_RS05825	COG1695	Transcriptional regulator
Q433_RS05840	COG3227	Zinc metalloprotease (Elastase)
Q433_RS05845	COG1307	EDD domain protein, DegV family
Q433_RS05850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_RS05870	COG0561	phosphatase activity
Q433_RS05875	COG1073	alpha beta
Q433_RS05880	COG2151	metal-sulfur cluster biosynthetic enzyme
Q433_RS05890	COG0277	FAD linked oxidase domain protein
Q433_RS05895	COG2271	Major facilitator Superfamily
Q433_RS05900	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Q433_RS05905	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Q433_RS05915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Q433_RS05920	COG0505	Belongs to the CarA family
Q433_RS05925	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Q433_RS05930	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Q433_RS05945	COG2267	carboxylic ester hydrolase activity
Q433_RS05955	COG1744	ABC transporter substrate-binding protein PnrA-like
Q433_RS05970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q433_RS05975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q433_RS05980	COG5504	Zn-dependent protease
Q433_RS05985	COG0444	Belongs to the ABC transporter superfamily
Q433_RS05990	COG4608	Belongs to the ABC transporter superfamily
Q433_RS06000	COG0601	transmembrane transport
Q433_RS06005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q433_RS06015	COG0180	Tryptophanyl-tRNA synthetase
Q433_RS06020	COG4166	transmembrane transport
Q433_RS06025	COG0601	transmembrane transport
Q433_RS06030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q433_RS06035	COG0444	Belongs to the ABC transporter superfamily
Q433_RS06040	COG4608	Belongs to the ABC transporter superfamily
Q433_RS06045	COG2814	Major facilitator Superfamily
Q433_RS06050	COG0456	acetyltransferase
Q433_RS06055	COG1393	Belongs to the ArsC family
Q433_RS06060	COG0861	Integral membrane protein TerC family
Q433_RS06065	COG4862	establishment of competence for transformation
Q433_RS06070	COG4469	Competence protein
Q433_RS06075	COG1164	Oligoendopeptidase f
Q433_RS06095	COG2346	COG2346, Truncated hemoglobins
Q433_RS06100	COG0741	lytic transglycosylase activity
Q433_RS06105	COG4116	CYTH
Q433_RS06115	COG2357	RelA SpoT domain protein
Q433_RS06120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Q433_RS06125	COG0564	pseudouridine synthase activity
Q433_RS06130	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Q433_RS06135	COG0569	domain protein
Q433_RS06135	COG0475	glutathione-regulated potassium exporter activity
Q433_RS06140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Q433_RS06145	COG0352	thiamine-phosphate diphosphorylase activity
Q433_RS06150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q433_RS06155	COG2104	thiamine diphosphate biosynthetic process
Q433_RS06160	COG2022	thiamine diphosphate biosynthetic process
Q433_RS06165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Q433_RS06170	COG0351	phosphomethylpyrimidine kinase
Q433_RS06175	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Q433_RS06235	COG0210	DNA helicase
Q433_RS06245	COG2153	protein acetylation
Q433_RS06250	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Q433_RS06255	COG2382	esterase
Q433_RS06260	COG0626	cystathionine gamma-synthase activity
Q433_RS06265	COG0626	cystathionine gamma-synthase activity
Q433_RS06275	COG5505	Protein of unknown function (DUF819)
Q433_RS06300	COG5444	nuclease activity
Q433_RS06340	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Q433_RS06345	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS06355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_RS06355	COG3711	transcriptional antiterminator
Q433_RS06360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Q433_RS06360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Q433_RS06360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_RS06365	COG1482	cell wall glycoprotein biosynthetic process
Q433_RS06375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_RS06385	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Q433_RS06400	COG0109	protoheme IX farnesyltransferase activity
Q433_RS06410	COG0726	polysaccharide deacetylase
Q433_RS06430	COG5504	Zn-dependent protease
Q433_RS06435	COG2205	protein histidine kinase activity
Q433_RS06445	COG3383	formate dehydrogenase (NAD+) activity
Q433_RS06450	COG2427	Protein of unknown function (DUF1641)
Q433_RS06460	COG1051	belongs to the nudix hydrolase family
Q433_RS06470	COG2124	cytochrome p450
Q433_RS06475	COG1819	glycosyl
Q433_RS06485	COG1587	Uroporphyrinogen-III synthase
Q433_RS06490	COG0390	transport system, permease component
Q433_RS06495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Q433_RS06500	COG0697	spore germination
Q433_RS06505	COG4297	protein containing double-stranded beta helix domain
Q433_RS06515	COG1252	NADH dehydrogenase
Q433_RS06520	COG1904	glucuronate isomerase
Q433_RS06525	COG2211	Major facilitator Superfamily
Q433_RS06530	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Q433_RS06535	COG1063	alcohol dehydrogenase
Q433_RS06540	COG1312	Catalyzes the dehydration of D-mannonate
Q433_RS06545	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS06550	COG2271	Major facilitator Superfamily
Q433_RS06555	COG1609	Transcriptional regulator
Q433_RS06560	COG0246	Mannitol dehydrogenase
Q433_RS06565	COG2721	sulfolactate sulfo-lyase activity
Q433_RS06570	COG0730	response to heat
Q433_RS06575	COG2318	DinB family
Q433_RS06580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q433_RS06585	COG0457	Tetratricopeptide repeat
Q433_RS06595	COG2350	Protein conserved in bacteria
Q433_RS06600	COG5632	N-Acetylmuramoyl-L-alanine amidase
Q433_RS06600	COG3409	Peptidoglycan-binding domain 1 protein
Q433_RS06600	COG1388	LysM domain
Q433_RS06610	COG4195	phage-related replication protein
Q433_RS06615	COG3546	catalase activity
Q433_RS06620	COG2856	Zn peptidase
Q433_RS06625	COG1396	sequence-specific DNA binding
Q433_RS06635	COG1522	sequence-specific DNA binding
Q433_RS06640	COG1484	DNA-dependent DNA replication
Q433_RS06665	COG1595	DNA-templated transcription, initiation
Q433_RS06670	COG3728	DNA packaging
Q433_RS06670	COG5484	DNA packaging
Q433_RS06675	COG1783	phage Terminase large subunit
Q433_RS06680	COG5518	Phage portal protein
Q433_RS06685	COG0338	D12 class N6 adenine-specific DNA methyltransferase
Q433_RS06690	COG4653	Phage capsid family
Q433_RS06740	COG5412	phage tail tape measure protein
Q433_RS06740	COG3953	SLT domain
Q433_RS06740	COG3953	SLT domain
Q433_RS06740	COG5412	phage tail tape measure protein
Q433_RS06745	COG1652	LysM domain
Q433_RS06750	COG4193	domain, Protein
Q433_RS06760	COG3628	GPW Gp25 family protein
Q433_RS06765	COG3299	homolog of phage Mu protein gp47
Q433_RS06770	COG3778	Protein conserved in bacteria
Q433_RS06810	COG5632	N-Acetylmuramoyl-L-alanine amidase
Q433_RS06810	COG3409	Peptidoglycan-binding domain 1 protein
Q433_RS06825	COG0306	phosphate transporter
Q433_RS06830	COG1392	Phosphate transport regulator
Q433_RS06835	COG0531	amino acid
Q433_RS06840	COG0346	lactoylglutathione lyase activity
Q433_RS06845	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Q433_RS06850	COG0463	Glycosyl transferase, family 2
Q433_RS06860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q433_RS06865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Q433_RS06870	COG2362	D-Aminopeptidase
Q433_RS06875	COG0601	transmembrane transport
Q433_RS06880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q433_RS06885	COG0444	Belongs to the ABC transporter superfamily
Q433_RS06890	COG4166	transmembrane transport
Q433_RS06895	COG1619	proteins homologs of microcin C7 resistance protein MccF
Q433_RS06900	COG4948	Mandelate Racemase Muconate Lactonizing
Q433_RS06905	COG0791	NLP P60 protein
Q433_RS06910	COG4608	Belongs to the ABC transporter superfamily
Q433_RS06915	COG2706	6-phosphogluconolactonase activity
Q433_RS06920	COG1834	amidinotransferase
Q433_RS06925	COG1607	acyl-coa hydrolase
Q433_RS06930	COG1017	nitric oxide dioxygenase activity
Q433_RS06930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Q433_RS06940	COG2323	membrane
Q433_RS06945	COG2318	DinB family
Q433_RS06950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_RS06955	COG2076	Multidrug Resistance protein
Q433_RS06960	COG2076	Multidrug Resistance protein
Q433_RS06965	COG0788	formyltetrahydrofolate deformylase activity
Q433_RS06970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Q433_RS06975	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Q433_RS06980	COG1764	response to oxidative stress
Q433_RS06985	COG1846	Transcriptional regulator
Q433_RS06990	COG1764	response to oxidative stress
Q433_RS07000	COG0590	tRNA wobble adenosine to inosine editing
Q433_RS07005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Q433_RS07010	COG1404	Belongs to the peptidase S8 family
Q433_RS07015	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_RS07020	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Q433_RS07025	COG1122	ATPase activity
Q433_RS07030	COG4721	ABC-type cobalt transport system, permease component
Q433_RS07040	COG0745	RESPONSE REGULATOR receiver
Q433_RS07045	COG5002	protein histidine kinase activity
Q433_RS07045	COG3850	Histidine kinase
Q433_RS07050	COG3212	peptidase
Q433_RS07055	COG3212	peptidase
Q433_RS07075	COG2239	Acts as a magnesium transporter
Q433_RS07080	COG0789	Transcriptional regulator
Q433_RS07095	COG1846	Transcriptional regulator
Q433_RS07100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Q433_RS07105	COG0726	polysaccharide deacetylase
Q433_RS07110	COG1408	metallophosphoesterase
Q433_RS07120	COG0463	Glycosyl transferase, family 2
Q433_RS07125	COG1793	dna ligase
Q433_RS07125	COG3285	dna ligase
Q433_RS07130	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Q433_RS07135	COG3300	MHYT domain
Q433_RS07135	COG5001	Diguanylate cyclase
Q433_RS07140	COG0586	Pfam SNARE associated Golgi protein
Q433_RS07145	COG0861	Integral membrane protein TerC family
Q433_RS07150	COG1191	sigma factor activity
Q433_RS07170	COG0501	Belongs to the peptidase M48B family
Q433_RS07175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Q433_RS07190	COG3594	Acyltransferase
Q433_RS07195	COG5002	protein histidine kinase activity
Q433_RS07200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Q433_RS07210	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Q433_RS07215	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
Q433_RS07220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Q433_RS07225	COG0436	Aminotransferase
Q433_RS07230	COG1850	ribulose-bisphosphate carboxylase activity
Q433_RS07235	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
Q433_RS07240	COG0235	Class ii aldolase
Q433_RS07245	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
Q433_RS07250	COG3339	Conserved Protein
Q433_RS07265	COG3852	Histidine kinase
Q433_RS07270	COG1846	Transcriptional regulator
Q433_RS07275	COG1360	Flagellar Motor Protein
Q433_RS07280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Q433_RS07285	COG0542	response to heat
Q433_RS07290	COG3949	Membrane
Q433_RS07295	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Q433_RS07300	COG0720	synthase
Q433_RS07305	COG0602	queuosine metabolic process
Q433_RS07310	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Q433_RS07315	COG1733	regulation of RNA biosynthetic process
Q433_RS07320	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS07325	COG1388	LysM domain
Q433_RS07325	COG4641	Protein conserved in bacteria
Q433_RS07330	COG1388	LysM domain
Q433_RS07335	COG3858	chitin binding
Q433_RS07345	COG4873	Protein conserved in bacteria
Q433_RS07360	COG3773	Cell wall hydrolase
Q433_RS07365	COG2244	polysaccharide biosynthetic process
Q433_RS07370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_RS07375	COG2217	Heavy metal translocating P-type atpase
Q433_RS07385	COG0006	proline dipeptidase activity
Q433_RS07395	COG1609	Transcriptional regulator
Q433_RS07400	COG3711	transcriptional antiterminator
Q433_RS07405	COG1263	PTS System
Q433_RS07405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_RS07405	COG2190	(PTS) system
Q433_RS07410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_RS07415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Q433_RS07425	COG1533	DNA photolyase activity
Q433_RS07430	COG0456	acetyltransferase
Q433_RS07435	COG0840	transmembrane signaling receptor activity
Q433_RS07440	COG2084	Dehydrogenase
Q433_RS07445	COG2340	Cysteine-rich secretory protein family
Q433_RS07450	COG0768	penicillin binding
Q433_RS07455	COG4191	Histidine kinase
Q433_RS07460	COG0436	Aminotransferase
Q433_RS07470	COG0784	Response regulator, receiver
Q433_RS07470	COG0835	chemotaxis
Q433_RS07480	COG2814	Major facilitator Superfamily
Q433_RS07485	COG1376	ErfK ybiS ycfS ynhG family protein
Q433_RS07490	COG1408	metallophosphoesterase
Q433_RS07495	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS07500	COG2200	EAL domain
Q433_RS07510	COG4703	Protein of unknown function (DUF1797)
Q433_RS07515	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Q433_RS07525	COG0517	IMP dehydrogenase activity
Q433_RS07530	COG0583	DNA-binding transcription factor activity
Q433_RS07535	COG0716	FMN binding
Q433_RS07545	COG0716	FMN binding
Q433_RS07550	COG2171	N-acyltransferase activity
Q433_RS07555	COG1473	amidohydrolase
Q433_RS07565	COG0668	transmembrane transport
Q433_RS07570	COG0450	alkyl hydroperoxide reductase
Q433_RS07575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_RS07590	COG0746	molybdenum cofactor guanylyltransferase activity
Q433_RS07595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Q433_RS07600	COG0303	'Molybdopterin
Q433_RS07605	COG1763	Mo-molybdopterin cofactor biosynthetic process
Q433_RS07610	COG0314	molybdopterin synthase activity
Q433_RS07615	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Q433_RS07620	COG1132	(ABC) transporter
Q433_RS07625	COG1132	(ABC) transporter
Q433_RS07635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q433_RS07640	COG1136	(ABC) transporter
Q433_RS07645	COG0577	efflux transmembrane transporter activity
Q433_RS07650	COG1349	DNA-binding transcription factor activity
Q433_RS07655	COG1105	Belongs to the carbohydrate kinase PfkB family
Q433_RS07660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Q433_RS07660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_RS07660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Q433_RS07665	COG0681	Belongs to the peptidase S26 family
Q433_RS07675	COG0488	(ABC) transporter
Q433_RS07680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Q433_RS07685	COG2309	aminopeptidase activity
Q433_RS07695	COG1077	Cell shape determining protein MreB Mrl
Q433_RS07700	COG2002	toxin-antitoxin pair type II binding
Q433_RS07705	COG3852	Histidine kinase
Q433_RS07710	COG2105	PFAM AIG2 family protein
Q433_RS07710	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
Q433_RS07715	COG0569	domain protein
Q433_RS07720	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Q433_RS07725	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Q433_RS07735	COG0561	phosphatase activity
Q433_RS07740	COG0242	peptide deformylase activity
Q433_RS07750	COG0497	DNA recombination
Q433_RS07755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Q433_RS07760	COG0022	dehydrogenase e1 component
Q433_RS07765	COG0508	dehydrogenase complex catalyzes the overall conversion of
Q433_RS07770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q433_RS07775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_RS07780	COG1982	Orn Lys Arg decarboxylase major
Q433_RS07785	COG4476	Belongs to the UPF0223 family
Q433_RS07790	COG4493	Belongs to the UPF0637 family
Q433_RS07800	COG0483	inositol monophosphate 1-phosphatase activity
Q433_RS07810	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Q433_RS07830	COG1595	DNA-templated transcription, initiation
Q433_RS07860	COG4896	Protein conserved in bacteria
Q433_RS07870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Q433_RS07875	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Q433_RS07880	COG2066	Belongs to the glutaminase family
Q433_RS07885	COG4838	Belongs to the UPF0358 family
Q433_RS07890	COG0772	Belongs to the SEDS family
Q433_RS07895	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Q433_RS07900	COG1612	heme a metabolic process
Q433_RS07905	COG0109	protoheme IX farnesyltransferase activity
Q433_RS07910	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Q433_RS07910	COG2010	Cytochrome c
Q433_RS07915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Q433_RS07920	COG1845	cytochrome c oxidase, subunit III
Q433_RS07925	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Q433_RS07930	COG3336	cytochrome c oxidase
Q433_RS07940	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Q433_RS07945	COG2340	Cysteine-rich secretory protein family
Q433_RS07960	COG3679	Belongs to the UPF0342 family
Q433_RS07965	COG4471	UPF0298 protein
Q433_RS07970	COG0742	ribosomal rna small subunit methyltransferase
Q433_RS07975	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Q433_RS07980	COG3314	Sporulation integral membrane protein YlbJ
Q433_RS07985	COG1752	Esterase of the alpha-beta hydrolase superfamily
Q433_RS07990	COG3480	Lon protease (S16) C-terminal proteolytic domain
Q433_RS07995	COG1323	Belongs to the UPF0348 family
Q433_RS08005	COG1399	metal-binding, possibly nucleic acid-binding protein
Q433_RS08020	COG0454	-acetyltransferase
Q433_RS08025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Q433_RS08030	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
Q433_RS08035	COG2001	Belongs to the MraZ family
Q433_RS08040	COG0275	rRNA processing
Q433_RS08045	COG4839	cell division protein FtsL
Q433_RS08060	COG0768	penicillin binding
Q433_RS08070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Q433_RS08080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Q433_RS08085	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Q433_RS08090	COG0772	Belongs to the SEDS family
Q433_RS08095	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Q433_RS08100	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Q433_RS08105	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Q433_RS08110	COG3879	Bacterial protein of unknown function (DUF881)
Q433_RS08115	COG3879	Bacterial protein of unknown function (DUF881)
Q433_RS08120	COG3856	small basic protein
Q433_RS08125	COG0849	cell division
Q433_RS08130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Q433_RS08135	COG1404	Belongs to the peptidase S8 family
Q433_RS08135	COG4412	M6 family metalloprotease domain protein
Q433_RS08145	COG1191	sigma factor activity
Q433_RS08150	COG1191	sigma factor activity
Q433_RS08155	COG1119	ATPase activity
Q433_RS08160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q433_RS08165	COG1873	PFAM PRC-barrel domain
Q433_RS08175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Q433_RS08180	COG1799	cell septum assembly
Q433_RS08185	COG0762	integral membrane protein
Q433_RS08190	COG2302	S4 RNA-binding domain
Q433_RS08195	COG3599	regulation of cell shape
Q433_RS08200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Q433_RS08205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Q433_RS08210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Q433_RS08215	COG0564	pseudouridine synthase activity
Q433_RS08220	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Q433_RS08225	COG2233	PERMEase
Q433_RS08230	COG0540	Belongs to the ATCase OTCase family
Q433_RS08235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Q433_RS08240	COG0505	Belongs to the CarA family
Q433_RS08245	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Q433_RS08250	COG0543	2 iron, 2 sulfur cluster binding
Q433_RS08255	COG0167	dihydroorotate dehydrogenase activity
Q433_RS08260	COG0284	orotidine-5'-phosphate decarboxylase activity
Q433_RS08265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Q433_RS08275	COG0175	sulfate reduction
Q433_RS08280	COG0306	phosphate transporter
Q433_RS08285	COG2046	Belongs to the sulfate adenylyltransferase family
Q433_RS08290	COG0529	Catalyzes the synthesis of activated sulfate
Q433_RS08295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Q433_RS08300	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
Q433_RS08305	COG1648	precorrin-2 dehydrogenase activity
Q433_RS08310	COG1293	RNA-binding protein homologous to eukaryotic snRNP
Q433_RS08315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Q433_RS08320	COG1561	YicC-like family, N-terminal region
Q433_RS08330	COG0194	GDP metabolic process
Q433_RS08335	COG1758	RNA polymerase activity
Q433_RS08340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Q433_RS08345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Q433_RS08350	COG0242	peptide deformylase activity
Q433_RS08355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Q433_RS08360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Q433_RS08360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Q433_RS08365	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Q433_RS08370	COG0631	protein serine/threonine phosphatase activity
Q433_RS08375	COG0515	serine threonine protein kinase
Q433_RS08375	COG2815	serine threonine protein kinase
Q433_RS08380	COG1162	GTPase activity
Q433_RS08385	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Q433_RS08390	COG1564	THIamine pyrophosphokinase
Q433_RS08400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Q433_RS08405	COG1302	Protein conserved in bacteria
Q433_RS08410	COG1461	Dihydroxyacetone kinase
Q433_RS08415	COG1760	l-serine dehydratase
Q433_RS08420	COG1760	l-serine dehydratase
Q433_RS08425	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Q433_RS08430	COG2050	protein possibly involved in aromatic compounds catabolism
Q433_RS08430	COG1349	DNA-binding transcription factor activity
Q433_RS08435	COG0416	fatty acid biosynthetic process
Q433_RS08440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Q433_RS08445	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS08455	COG0571	ribonuclease III activity
Q433_RS08460	COG1196	nuclear chromosome segregation
Q433_RS08465	COG0552	protein localization to endoplasmic reticulum
Q433_RS08475	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
Q433_RS08480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Q433_RS08485	COG0228	four-way junction DNA binding
Q433_RS08490	COG1837	Belongs to the UPF0109 family
Q433_RS08500	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Q433_RS08505	COG0336	Belongs to the RNA methyltransferase TrmD family
Q433_RS08510	COG0335	large ribosomal subunit rRNA binding
Q433_RS08515	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Q433_RS08520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Q433_RS08530	COG2257	FlhB HrpN YscU SpaS Family
Q433_RS08535	COG0045	succinate-CoA ligase (ADP-forming) activity
Q433_RS08540	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Q433_RS08545	COG0758	DNA mediated transformation
Q433_RS08550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Q433_RS08555	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Q433_RS08560	COG4974	Belongs to the 'phage' integrase family
Q433_RS08565	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Q433_RS08570	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Q433_RS08575	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Q433_RS08580	COG1815	bacterial-type flagellum-dependent cell motility
Q433_RS08585	COG1558	bacterial-type flagellum-dependent cell motility
Q433_RS08590	COG1677	Flagellar hook-basal body complex protein FliE
Q433_RS08595	COG1766	The M ring may be actively involved in energy transduction
Q433_RS08600	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Q433_RS08605	COG1317	bacterial-type flagellum organization
Q433_RS08610	COG1157	protein secretion by the type III secretion system
Q433_RS08615	COG2882	bacterial-type flagellum organization
Q433_RS08620	COG3334	PFAM MgtE intracellular
Q433_RS08625	COG3144	bacterial-type flagellum assembly
Q433_RS08630	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Q433_RS08635	COG4786	Flagellar basal body rod
Q433_RS08640	COG1582	Flagellar protein (FlbD)
Q433_RS08645	COG1580	Controls the rotational direction of flagella during chemotaxis
Q433_RS08650	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Q433_RS08655	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Q433_RS08655	COG1776	CheC inhibitor of MCP methylation
Q433_RS08660	COG2201	protein-glutamate methylesterase activity
Q433_RS08665	COG3190	flagellar
Q433_RS08670	COG1338	Plays a role in the flagellum-specific transport system
Q433_RS08675	COG1987	bacterial-type flagellum assembly
Q433_RS08680	COG1684	flagellar biosynthetic protein fliR
Q433_RS08685	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Q433_RS08690	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Q433_RS08695	COG1419	protein localization to endoplasmic reticulum
Q433_RS08700	COG0455	bacterial-type flagellum organization
Q433_RS08705	COG2201	protein-glutamate methylesterase activity
Q433_RS08710	COG2198	Histidine kinase
Q433_RS08710	COG0643	Histidine kinase
Q433_RS08715	COG0835	chemotaxis
Q433_RS08720	COG1776	CheC inhibitor of MCP methylation
Q433_RS08725	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Q433_RS08730	COG1191	sigma factor activity
Q433_RS08740	COG0052	Belongs to the universal ribosomal protein uS2 family
Q433_RS08745	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Q433_RS08750	COG0528	UMP kinase activity
Q433_RS08755	COG0233	cytoplasmic translational termination
Q433_RS08760	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Q433_RS08765	COG4589	Belongs to the CDS family
Q433_RS08770	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Q433_RS08775	COG0750	zinc metalloprotease
Q433_RS08780	COG0442	prolyl-tRNA aminoacylation
Q433_RS08785	COG2176	DNA-directed DNA polymerase activity
Q433_RS08790	COG0779	Required for maturation of 30S ribosomal subunits
Q433_RS08795	COG0195	Participates in both transcription termination and antitermination
Q433_RS08800	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Q433_RS08805	COG1358	cellular component organization or biogenesis
Q433_RS08810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Q433_RS08815	COG1550	Protein conserved in bacteria
Q433_RS08820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Q433_RS08825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Q433_RS08830	COG0196	riboflavin kinase activity
Q433_RS08835	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Q433_RS08840	COG1185	polyribonucleotide nucleotidyltransferase activity
Q433_RS08845	COG0726	polysaccharide deacetylase
Q433_RS08850	COG0612	Peptidase, M16
Q433_RS08855	COG1873	PFAM PRC-barrel domain
Q433_RS08865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Q433_RS08870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Q433_RS08875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Q433_RS08880	COG0527	aspartate kinase activity
Q433_RS08885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q433_RS08890	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Q433_RS08895	COG0740	serine-type endopeptidase activity
Q433_RS08905	COG1674	ftsk spoiiie
Q433_RS08905	COG4980	gas vesicle protein
Q433_RS08910	COG2188	Transcriptional regulator
Q433_RS08915	COG2814	Major facilitator Superfamily
Q433_RS08920	COG0612	Peptidase, M16
Q433_RS08925	COG0612	Peptidase, M16
Q433_RS08930	COG0300	oxidoreductase activity
Q433_RS08945	COG1426	Protein conserved in bacteria
Q433_RS08950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Q433_RS08955	COG1546	Belongs to the CinA family
Q433_RS08955	COG1058	Belongs to the CinA family
Q433_RS08960	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Q433_RS08965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Q433_RS08970	COG1418	mRNA catabolic process
Q433_RS08975	COG1692	metallophosphoesterase
Q433_RS08980	COG2359	stage V sporulation protein S
Q433_RS08985	COG1063	alcohol dehydrogenase
Q433_RS08990	COG0156	8-amino-7-oxononanoate synthase activity
Q433_RS08995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Q433_RS09000	COG4550	Control of competence regulator ComK, YlbF/YmcA
Q433_RS09010	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Q433_RS09015	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Q433_RS09035	COG3226	Transcriptional regulator
Q433_RS09040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_RS09050	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Q433_RS09055	COG3321	synthase
Q433_RS09060	COG2070	2-Nitropropane dioxygenase
Q433_RS09060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Q433_RS09065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q433_RS09070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q433_RS09075	COG3425	synthase
Q433_RS09080	COG1024	Enoyl-CoA hydratase
Q433_RS09085	COG1024	Enoyl-CoA hydratase
Q433_RS09090	COG0300	oxidoreductase activity
Q433_RS09090	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_RS09090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS09090	COG3321	synthase
Q433_RS09095	COG3321	synthase
Q433_RS09095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q433_RS09095	COG4221	oxidoreductase activity
Q433_RS09095	COG0300	oxidoreductase activity
Q433_RS09100	COG3321	synthase
Q433_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS09100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_RS09100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q433_RS09100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q433_RS09105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_RS09105	COG4221	oxidoreductase activity
Q433_RS09105	COG3321	synthase
Q433_RS09105	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS09110	COG3321	synthase
Q433_RS09110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Q433_RS09110	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
Q433_RS09110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q433_RS09115	COG2124	cytochrome p450
Q433_RS09125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_RS09130	COG1404	Belongs to the peptidase S8 family
Q433_RS09140	COG4195	phage-related replication protein
Q433_RS09145	COG1764	response to oxidative stress
Q433_RS09150	COG2076	Multidrug Resistance protein
Q433_RS09155	COG2076	Multidrug Resistance protein
Q433_RS09170	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Q433_RS09175	COG1923	regulation of RNA biosynthetic process
Q433_RS09190	COG1780	Probably involved in ribonucleotide reductase function
Q433_RS09195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Q433_RS09200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Q433_RS09205	COG4112	unkown
Q433_RS09210	COG0860	N-Acetylmuramoyl-L-alanine amidase
Q433_RS09215	COG0464	growth
Q433_RS09225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Q433_RS09230	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Q433_RS09235	COG0789	Transcriptional regulator
Q433_RS09240	COG0174	glutamine synthetase
Q433_RS09245	COG4974	Belongs to the 'phage' integrase family
Q433_RS09325	COG0582	viral genome integration into host DNA
Q433_RS09335	COG1598	PFAM Uncharacterised protein family UPF0150
Q433_RS09425	COG3953	SLT domain
Q433_RS09425	COG5280	Phage tail tape measure protein TP901
Q433_RS09435	COG1705	Flagellar rod assembly protein muramidase FlgJ
Q433_RS09465	COG4824	toxin secretion phage lysis holin
Q433_RS09470	COG5632	N-Acetylmuramoyl-L-alanine amidase
Q433_RS09470	COG1388	LysM domain
Q433_RS09470	COG3409	Peptidoglycan-binding domain 1 protein
Q433_RS09480	COG5444	nuclease activity
Q433_RS09525	COG0463	Glycosyl transferase, family 2
Q433_RS09545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_RS09560	COG3655	Transcriptional regulator
Q433_RS09575	COG0135	phosphoribosylanthranilate isomerase activity
Q433_RS09585	COG2211	Major facilitator Superfamily
Q433_RS09590	COG3507	Belongs to the glycosyl hydrolase 43 family
Q433_RS09595	COG1940	carbohydrate kinase activity
Q433_RS09600	COG2115	Belongs to the xylose isomerase family
Q433_RS09605	COG1070	Carbohydrate kinase
Q433_RS09610	COG1525	nuclease
Q433_RS09615	COG2814	Major facilitator Superfamily
Q433_RS09620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Q433_RS09630	COG0756	dUTP diphosphatase activity
Q433_RS09665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Q433_RS09680	COG3832	glyoxalase III activity
Q433_RS09730	COG4195	phage-related replication protein
Q433_RS09740	COG0346	lactoylglutathione lyase activity
Q433_RS09750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Q433_RS09755	COG1388	LysM domain
Q433_RS09760	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Q433_RS09765	COG4224	UPF0291 protein
Q433_RS09770	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Q433_RS09780	COG3763	UPF0154 protein
Q433_RS09790	COG0785	Cytochrome C biogenesis protein
Q433_RS09795	COG2201	protein-glutamate methylesterase activity
Q433_RS09800	COG4846	Membrane protein involved in cytochrome C biogenesis
Q433_RS09810	COG0071	Belongs to the small heat shock protein (HSP20) family
Q433_RS09825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Q433_RS09830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_RS09850	COG0824	Thioesterase
Q433_RS09860	COG4841	protein insertion into membrane
Q433_RS09865	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Q433_RS09870	COG1832	CoA-binding protein
Q433_RS09875	COG0187	DNA topoisomerase II activity
Q433_RS09880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Q433_RS09895	COG1115	amino acid carrier protein
Q433_RS09910	COG5520	Belongs to the glycosyl hydrolase 30 family
Q433_RS09915	COG3507	Belongs to the glycosyl hydrolase 43 family
Q433_RS09925	COG2246	polysaccharide biosynthetic process
Q433_RS09930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Q433_RS09935	COG0586	Pfam SNARE associated Golgi protein
Q433_RS09940	COG2404	hydrolase activity, acting on ester bonds
Q433_RS09945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Q433_RS09950	COG1024	Enoyl-CoA hydratase
Q433_RS09955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Q433_RS09960	COG0511	ligase activity, forming carbon-carbon bonds
Q433_RS09965	COG0439	Biotin carboxylase
Q433_RS09970	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_RS09975	COG1960	acyl-CoA dehydrogenase activity
Q433_RS09990	COG1649	PFAM Uncharacterised BCR, COG1649
Q433_RS10000	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
Q433_RS10000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_RS10005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_RS10015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_RS10020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_RS10025	COG2027	D-alanyl-D-alanine carboxypeptidase
Q433_RS10030	COG2017	converts alpha-aldose to the beta-anomer
Q433_RS10035	COG0534	Mate efflux family protein
Q433_RS10050	COG0582	viral genome integration into host DNA
Q433_RS10055	COG0166	Belongs to the GPI family
Q433_RS10060	COG0405	Gamma-glutamyltransferase
Q433_RS10065	COG0583	DNA-binding transcription factor activity
Q433_RS10070	COG0604	alcohol dehydrogenase
Q433_RS10075	COG0493	'glutamate synthase
Q433_RS10080	COG0070	glutamate synthase
Q433_RS10080	COG0069	glutamate synthase activity
Q433_RS10080	COG0067	glutamate synthase
Q433_RS10085	COG0583	DNA-binding transcription factor activity
Q433_RS10090	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Q433_RS10095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Q433_RS10105	COG0300	oxidoreductase activity
Q433_RS10110	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
Q433_RS10120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_RS10140	COG2814	Major facilitator Superfamily
Q433_RS10145	COG1070	Carbohydrate kinase
Q433_RS10150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Q433_RS10155	COG0243	molybdopterin cofactor binding
Q433_RS10180	COG0840	transmembrane signaling receptor activity
Q433_RS10180	COG5278	phosphoserine phosphatase activity
Q433_RS10185	COG2368	4-hydroxyphenylacetate
Q433_RS10190	COG4305	rare lipoprotein A
Q433_RS10195	COG3619	membrane
Q433_RS10200	COG3866	Pectate lyase
Q433_RS10205	COG2135	peptidase activity
Q433_RS10215	COG2140	Oxalate decarboxylase
Q433_RS10225	COG0456	acetyltransferase
Q433_RS10245	COG2720	vancomycin resistance protein
Q433_RS10255	COG3655	Transcriptional regulator
Q433_RS10260	COG3739	integral membrane protein
Q433_RS10265	COG0583	DNA-binding transcription factor activity
Q433_RS10270	COG0697	spore germination
Q433_RS10280	COG0693	protein deglycase activity
Q433_RS10285	COG2367	Beta-lactamase
Q433_RS10305	COG3848	Pyruvate phosphate dikinase
Q433_RS10305	COG0574	Belongs to the PEP-utilizing enzyme family
Q433_RS10310	COG0726	polysaccharide deacetylase
Q433_RS10320	COG2314	TM2 domain
Q433_RS10325	COG1396	sequence-specific DNA binding
Q433_RS10430	COG0457	Tetratricopeptide repeat
Q433_RS10465	COG4282	regulation of fungal-type cell wall biogenesis
Q433_RS10470	COG1231	oxidoreductase activity
Q433_RS10475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q433_RS10480	COG0662	Cupin 2, conserved barrel domain protein
Q433_RS10480	COG2207	Transcriptional regulator
Q433_RS10485	COG0456	acetyltransferase
Q433_RS10490	COG1309	transcriptional regulator
Q433_RS10495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_RS10500	COG3708	Transcriptional regulator
Q433_RS10505	COG2378	regulation of single-species biofilm formation
Q433_RS10515	COG0640	Transcriptional regulator
Q433_RS10520	COG0741	lytic transglycosylase activity
Q433_RS10525	COG2322	membrane
Q433_RS10540	COG1619	proteins homologs of microcin C7 resistance protein MccF
Q433_RS10545	COG3239	Fatty acid desaturase
Q433_RS10550	COG4585	Histidine kinase
Q433_RS10555	COG2197	response regulator
Q433_RS10565	COG3584	3D domain protein
Q433_RS10565	COG1388	LysM domain
Q433_RS10570	COG0514	ATP-dependent DNA helicase (RecQ)
Q433_RS10580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Q433_RS10585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Q433_RS10600	COG0071	Belongs to the small heat shock protein (HSP20) family
Q433_RS10625	COG1012	belongs to the aldehyde dehydrogenase family
Q433_RS10630	COG1657	PFAM Prenyltransferase squalene oxidase
Q433_RS10635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Q433_RS10640	COG0733	neurotransmitter:sodium symporter activity
Q433_RS10645	COG0385	Bile acid
Q433_RS10650	COG0508	dehydrogenase complex catalyzes the overall conversion of
Q433_RS10655	COG0567	Dehydrogenase, E1 component
Q433_RS10660	COG4548	von Willebrand factor, type A
Q433_RS10665	COG0714	Associated with various cellular activities
Q433_RS10670	COG2032	superoxide dismutase activity
Q433_RS10675	COG1388	LysM domain
Q433_RS10675	COG0791	NLP P60 protein
Q433_RS10680	COG1819	glycosyl
Q433_RS10685	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Q433_RS10690	COG0534	Mate efflux family protein
Q433_RS10695	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_RS10700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Q433_RS10705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Q433_RS10715	COG2962	Rard protein
Q433_RS10730	COG2610	gluconate transmembrane transporter activity
Q433_RS10735	COG1942	4-Oxalocrotonate Tautomerase
Q433_RS10740	COG1733	regulation of RNA biosynthetic process
Q433_RS10745	COG0778	Nitroreductase
Q433_RS10750	COG0400	carboxylic ester hydrolase activity
Q433_RS10755	COG0346	lactoylglutathione lyase activity
Q433_RS10765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q433_RS10770	COG0793	Belongs to the peptidase S41A family
Q433_RS10770	COG3409	Peptidoglycan-binding domain 1 protein
Q433_RS10775	COG2226	methyltransferase
Q433_RS10785	COG1876	peptidase activity
Q433_RS10790	COG0813	purine-nucleoside phosphorylase activity
Q433_RS10805	COG0671	phosphoesterase, PA-phosphatase related
Q433_RS10830	COG4479	Belongs to the UPF0346 family
Q433_RS10840	COG1509	lysine 2,3-aminomutase activity
Q433_RS10850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q433_RS10855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Q433_RS10860	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Q433_RS10865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Q433_RS10880	COG0456	acetyltransferase
Q433_RS10885	COG0463	Glycosyl transferase, family 2
Q433_RS10900	COG4641	Protein conserved in bacteria
Q433_RS10905	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
Q433_RS10915	COG1086	Polysaccharide biosynthesis protein
Q433_RS10920	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q433_RS10925	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q433_RS10930	COG1846	Transcriptional regulator
Q433_RS10935	COG0534	Mate efflux family protein
Q433_RS10945	COG4698	Protein conserved in bacteria
Q433_RS10950	COG2755	lipolytic protein G-D-S-L family
Q433_RS10955	COG1999	signal sequence binding
Q433_RS10970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Q433_RS10975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Q433_RS10980	COG1272	protein, Hemolysin III
Q433_RS10985	COG0204	Acyl-transferase
Q433_RS10990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Q433_RS10995	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Q433_RS11000	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Q433_RS11010	COG2136	Putative SAM-dependent methyltransferase
Q433_RS11010	COG2521	methyltransferase
Q433_RS11020	COG0129	dihydroxy-acid dehydratase activity
Q433_RS11025	COG1413	lyase activity
Q433_RS11030	COG1418	mRNA catabolic process
Q433_RS11035	COG0386	Belongs to the glutathione peroxidase family
Q433_RS11040	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Q433_RS11045	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Q433_RS11050	COG1278	Cold shock
Q433_RS11070	COG0328	RNA-DNA hybrid ribonuclease activity
Q433_RS11075	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Q433_RS11080	COG0328	RNA-DNA hybrid ribonuclease activity
Q433_RS11090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q433_RS11110	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Q433_RS11115	COG1755	Isoprenylcysteine carboxyl methyltransferase
Q433_RS11120	COG3424	synthase
Q433_RS11125	COG2233	PERMEase
Q433_RS11130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Q433_RS11135	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Q433_RS11145	COG0800	Aldolase
Q433_RS11150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q433_RS11155	COG1609	Transcriptional regulator
Q433_RS11160	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
Q433_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS11170	COG1199	ATP-dependent helicase activity
Q433_RS11180	COG0116	Belongs to the methyltransferase superfamily
Q433_RS11190	COG4474	Belongs to the UPF0398 family
Q433_RS11200	COG3359	exonuclease
Q433_RS11205	COG1111	helicase
Q433_RS11205	COG1205	dead DEAH box helicase
Q433_RS11210	COG2190	(PTS) system
Q433_RS11215	COG0071	Belongs to the small heat shock protein (HSP20) family
Q433_RS11250	COG3331	DNA recombination
Q433_RS11255	COG4499	WXG100 protein secretion system (Wss), protein YukC
Q433_RS11255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Q433_RS11265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Q433_RS11270	COG3935	DnaD domain protein
Q433_RS11275	COG0017	Asparaginyl-tRNA synthetase
Q433_RS11280	COG0436	Aminotransferase
Q433_RS11285	COG5353	protein conserved in bacteria
Q433_RS11295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Q433_RS11295	COG1199	ATP-dependent helicase activity
Q433_RS11300	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Q433_RS11305	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Q433_RS11310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Q433_RS11315	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Q433_RS11315	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Q433_RS11320	COG0617	tRNA 3'-terminal CCA addition
Q433_RS11325	COG0438	transferase activity, transferring glycosyl groups
Q433_RS11330	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Q433_RS11335	COG1803	Methylglyoxal synthase
Q433_RS11340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Q433_RS11345	COG1694	Mazg nucleotide pyrophosphohydrolase
Q433_RS11350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_RS11360	COG4347	Protein of unknown function (DUF1405)
Q433_RS11365	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Q433_RS11365	COG2010	Cytochrome c
Q433_RS11370	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Q433_RS11375	COG0723	plastoquinol--plastocyanin reductase activity
Q433_RS11385	COG5582	Belongs to the UPF0302 family
Q433_RS11390	COG0457	Tetratricopeptide repeat
Q433_RS11395	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Q433_RS11400	COG0287	Prephenate dehydrogenase
Q433_RS11405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Q433_RS11410	COG0159	tryptophan synthase activity
Q433_RS11415	COG0133	tryptophan synthase activity
Q433_RS11420	COG0135	phosphoribosylanthranilate isomerase activity
Q433_RS11430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Q433_RS11435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Q433_RS11440	COG4401	Chorismate mutase type I
Q433_RS11445	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Q433_RS11450	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Q433_RS11455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Q433_RS11465	COG0105	UTP biosynthetic process
Q433_RS11470	COG0142	geranyltranstransferase activity
Q433_RS11475	COG2226	methyltransferase
Q433_RS11480	COG0142	geranyltranstransferase activity
Q433_RS11490	COG0302	gtp cyclohydrolase
Q433_RS11495	COG0776	regulation of translation
Q433_RS11500	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Q433_RS11515	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Q433_RS11520	COG1160	GTP binding
Q433_RS11545	COG1304	FMN binding
Q433_RS11550	COG0539	negative regulation of cytoplasmic translation
Q433_RS11555	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Q433_RS11565	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
Q433_RS11570	COG2959	enzyme of heme biosynthesis
Q433_RS11575	COG3409	Peptidoglycan-binding domain 1 protein
Q433_RS11575	COG3773	Cell wall hydrolase
Q433_RS11580	COG2339	peptidase activity
Q433_RS11585	COG0492	ferredoxin-NADP+ reductase activity
Q433_RS11590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Q433_RS11595	COG4862	establishment of competence for transformation
Q433_RS11600	COG1408	metallophosphoesterase
Q433_RS11610	COG1388	LysM domain
Q433_RS11615	COG1266	CAAX protease self-immunity
Q433_RS11620	COG0514	ATP-dependent DNA helicase (RecQ)
Q433_RS11625	COG4955	Helix-turn-helix domain
Q433_RS11630	COG1141	Ferredoxin
Q433_RS11635	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
Q433_RS11645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Q433_RS11650	COG0710	3-dehydroquinate dehydratase activity
Q433_RS11660	COG1595	DNA-templated transcription, initiation
Q433_RS11665	COG5002	protein histidine kinase activity
Q433_RS11670	COG0745	RESPONSE REGULATOR receiver
Q433_RS11675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Q433_RS11680	COG1333	cytochrome c biogenesis protein
Q433_RS11685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_RS11690	COG1187	pseudouridine synthase activity
Q433_RS11695	COG0700	Nucleoside recognition
Q433_RS11700	COG2715	membrane protein required for spore maturation
Q433_RS11705	COG1686	Belongs to the peptidase S11 family
Q433_RS11715	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Q433_RS11720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Q433_RS11725	COG1547	Domain of unknown function (DUF309)
Q433_RS11730	COG0456	acetyltransferase
Q433_RS11735	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Q433_RS11740	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Q433_RS11740	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Q433_RS11745	COG0307	riboflavin synthase, alpha
Q433_RS11750	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Q433_RS11750	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Q433_RS11760	COG0681	Belongs to the peptidase S26 family
Q433_RS11765	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
Q433_RS11785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Q433_RS11790	COG4086	secreted protein
Q433_RS11795	COG0019	diaminopimelate decarboxylase activity
Q433_RS11800	COG0697	spore germination
Q433_RS11815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q433_RS11835	COG1191	sigma factor activity
Q433_RS11840	COG2172	sigma factor antagonist activity
Q433_RS11845	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_RS11850	COG1686	Belongs to the peptidase S11 family
Q433_RS11855	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Q433_RS11860	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Q433_RS11865	COG4974	Belongs to the 'phage' integrase family
Q433_RS11875	COG0735	belongs to the Fur family
Q433_RS11880	COG1300	Membrane
Q433_RS11890	COG0281	malic enzyme
Q433_RS11895	COG1757	Na H antiporter
Q433_RS11900	COG1027	Aspartate ammonia-lyase
Q433_RS11905	COG0252	asparaginase activity
Q433_RS11910	COG1396	sequence-specific DNA binding
Q433_RS11915	COG1379	DNA repair
Q433_RS11920	COG0494	nUDIX hydrolase
Q433_RS11930	COG0667	Aldo Keto reductase
Q433_RS11940	COG1073	alpha beta
Q433_RS11950	COG4918	Iron-sulphur cluster biosynthesis
Q433_RS11955	COG0456	acetyltransferase
Q433_RS11955	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Q433_RS11960	COG2329	Antibiotic biosynthesis monooxygenase
Q433_RS11965	COG0456	acetyltransferase
Q433_RS11975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Q433_RS11985	COG2211	Major facilitator Superfamily
Q433_RS11995	COG0346	lactoylglutathione lyase activity
Q433_RS12000	COG1072	(Pantothenic acid kinase))
Q433_RS12005	COG3048	D-serine ammonia-lyase activity
Q433_RS12010	COG0300	oxidoreductase activity
Q433_RS12015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_RS12020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Q433_RS12025	COG4187	Peptidase family M20/M25/M40
Q433_RS12030	COG1902	pentaerythritol trinitrate reductase activity
Q433_RS12035	COG0596	Alpha beta hydrolase
Q433_RS12045	COG1234	tRNA 3'-trailer cleavage
Q433_RS12050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Q433_RS12055	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Q433_RS12060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Q433_RS12070	COG0706	membrane insertase activity
Q433_RS12075	COG3361	conserved protein (COG2071)
Q433_RS12080	COG2195	Cleaves the N-terminal amino acid of tripeptides
Q433_RS12085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Q433_RS12090	COG0346	lactoylglutathione lyase activity
Q433_RS12100	COG1376	ErfK ybiS ycfS ynhG family protein
Q433_RS12105	COG4129	membrane
Q433_RS12110	COG1126	abc transporter atp-binding protein
Q433_RS12115	COG0765	amino acid transport
Q433_RS12120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_RS12130	COG1597	lipid kinase activity
Q433_RS12135	COG2814	Major facilitator Superfamily
Q433_RS12140	COG0789	Transcriptional regulator
Q433_RS12140	COG4978	Transcriptional regulator
Q433_RS12145	COG0508	dehydrogenase complex catalyzes the overall conversion of
Q433_RS12150	COG0022	dehydrogenase e1 component
Q433_RS12165	COG3426	butyrate kinase activity
Q433_RS12170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Q433_RS12175	COG0280	phosphate acetyltransferase
Q433_RS12180	COG3290	protein histidine kinase activity
Q433_RS12180	COG3829	transcription factor binding
Q433_RS12190	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Q433_RS12195	COG2079	MmgE PrpD family protein
Q433_RS12200	COG0372	Belongs to the citrate synthase family
Q433_RS12205	COG1960	acyl-CoA dehydrogenase activity
Q433_RS12210	COG1250	3-hydroxyacyl-CoA dehydrogenase
Q433_RS12215	COG0183	Belongs to the thiolase family
Q433_RS12220	COG0584	glycerophosphoryl diester phosphodiesterase
Q433_RS12225	COG0860	N-Acetylmuramoyl-L-alanine amidase
Q433_RS12240	COG1902	pentaerythritol trinitrate reductase activity
Q433_RS12250	COG0745	RESPONSE REGULATOR receiver
Q433_RS12260	COG0750	zinc metalloprotease
Q433_RS12265	COG0497	DNA recombination
Q433_RS12270	COG1438	arginine binding
Q433_RS12275	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Q433_RS12280	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Q433_RS12285	COG0142	geranyltranstransferase activity
Q433_RS12290	COG1722	exodeoxyribonuclease VII activity
Q433_RS12295	COG1570	exodeoxyribonuclease VII activity
Q433_RS12300	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Q433_RS12305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Q433_RS12310	COG1302	Protein conserved in bacteria
Q433_RS12315	COG0439	Biotin carboxylase
Q433_RS12320	COG0511	ligase activity, forming carbon-carbon bonds
Q433_RS12360	COG3854	ATPases associated with a variety of cellular activities
Q433_RS12370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Q433_RS12375	COG0006	proline dipeptidase activity
Q433_RS12380	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Q433_RS12390	COG3872	metal-dependent enzyme
Q433_RS12400	COG1752	Esterase of the alpha-beta hydrolase superfamily
Q433_RS12405	COG1321	iron dependent repressor
Q433_RS12410	COG0095	Lipoate-protein ligase
Q433_RS12415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q433_RS12420	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Q433_RS12425	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Q433_RS12430	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Q433_RS12435	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q433_RS12450	COG1396	sequence-specific DNA binding
Q433_RS12460	COG0681	Belongs to the peptidase S26 family
Q433_RS12485	COG4940	Competence protein ComGF
Q433_RS12495	COG4970	Tfp pilus assembly protein FimT
Q433_RS12500	COG4537	Required for transformation and DNA binding
Q433_RS12505	COG1459	type II secretion system
Q433_RS12510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q433_RS12520	COG0517	IMP dehydrogenase activity
Q433_RS12525	COG0598	Magnesium transport protein CorA
Q433_RS12530	COG1253	flavin adenine dinucleotide binding
Q433_RS12535	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_RS12545	COG1393	Belongs to the ArsC family
Q433_RS12565	COG0011	TIGRFAM Protein of
Q433_RS12575	COG2866	Carboxypeptidase
Q433_RS12580	COG1368	sulfuric ester hydrolase activity
Q433_RS12585	COG1940	carbohydrate kinase activity
Q433_RS12590	COG4483	Protein conserved in bacteria
Q433_RS12595	COG0457	Tetratricopeptide repeat
Q433_RS12595	COG0705	Rhomboid family
Q433_RS12605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Q433_RS12615	COG0438	transferase activity, transferring glycosyl groups
Q433_RS12630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Q433_RS12635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Q433_RS12640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Q433_RS12645	COG0581	inorganic phosphate transmembrane transporter activity
Q433_RS12650	COG0573	inorganic phosphate transmembrane transporter activity
Q433_RS12655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Q433_RS12665	COG0477	Major facilitator Superfamily
Q433_RS12670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Q433_RS12675	COG2839	Protein conserved in bacteria
Q433_RS12680	COG5521	maltodextrose utilization protein MalA
Q433_RS12685	COG1388	LysM domain
Q433_RS12690	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Q433_RS12695	COG4709	membrane
Q433_RS12700	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
Q433_RS12705	COG0735	belongs to the Fur family
Q433_RS12710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_RS12720	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Q433_RS12725	COG0513	Belongs to the DEAD box helicase family
Q433_RS12735	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Q433_RS12740	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Q433_RS12745	COG2384	SAM-dependent methyltransferase
Q433_RS12750	COG2010	Cytochrome c
Q433_RS12755	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q433_RS12760	COG0358	DNA primase activity
Q433_RS12765	COG1671	Belongs to the UPF0178 family
Q433_RS12770	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Q433_RS12775	COG0517	IMP dehydrogenase activity
Q433_RS12780	COG0751	glycine-tRNA ligase activity
Q433_RS12785	COG0752	glycyl-tRNA synthetase alpha subunit
Q433_RS12790	COG1381	Involved in DNA repair and RecF pathway recombination
Q433_RS12800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Q433_RS12805	COG0295	cytidine deaminase activity
Q433_RS12810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Q433_RS12815	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Q433_RS12820	COG1480	7TM receptor with intracellular HD hydrolase
Q433_RS12830	COG1702	phosphate starvation-inducible protein PhoH
Q433_RS12835	COG0561	phosphatase activity
Q433_RS12850	COG4864	UPF0365 protein
Q433_RS12855	COG1030	water channel activity
Q433_RS12860	COG1610	YqeY-like protein
Q433_RS12870	COG1283	sodium-dependent phosphate transmembrane transporter activity
Q433_RS12875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Q433_RS12880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Q433_RS12885	COG2264	protein methyltransferase activity
Q433_RS12890	COG0484	heat shock protein binding
Q433_RS12895	COG0443	Heat shock 70 kDa protein
Q433_RS12900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Q433_RS12905	COG1420	regulation of RNA biosynthetic process
Q433_RS12910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Q433_RS12915	COG0481	GTPase activity
Q433_RS12925	COG0860	N-Acetylmuramoyl-L-alanine amidase
Q433_RS12930	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Q433_RS12935	COG0268	Binds directly to 16S ribosomal RNA
Q433_RS12940	COG1466	dna polymerase III delta subunit
Q433_RS12950	COG0658	competence protein
Q433_RS12950	COG2333	competence protein COMEC
Q433_RS12955	COG2131	deaminase
Q433_RS12960	COG1555	photosystem II stabilization
Q433_RS12960	COG1596	polysaccharide export
Q433_RS12965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Q433_RS12970	COG2226	methyltransferase
Q433_RS12975	COG0799	negative regulation of ribosome biogenesis
Q433_RS12980	COG1713	HD superfamily hydrolase involved in NAD metabolism
Q433_RS12985	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Q433_RS12990	COG1534	Rna-binding protein
Q433_RS12995	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Q433_RS13000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Q433_RS13005	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Q433_RS13020	COG2755	lipolytic protein G-D-S-L family
Q433_RS13025	COG3409	Peptidoglycan-binding domain 1 protein
Q433_RS13025	COG5632	N-Acetylmuramoyl-L-alanine amidase
Q433_RS13030	COG0398	Pfam SNARE associated Golgi protein
Q433_RS13045	COG3209	COG3209 Rhs family protein
Q433_RS13060	COG5002	protein histidine kinase activity
Q433_RS13060	COG0642	Histidine kinase
Q433_RS13065	COG0745	RESPONSE REGULATOR receiver
Q433_RS13070	COG2311	Membrane
Q433_RS13080	COG0454	-acetyltransferase
Q433_RS13085	COG2249	NAD(P)H dehydrogenase (quinone) activity
Q433_RS13095	COG0730	response to heat
Q433_RS13100	COG0425	Belongs to the sulfur carrier protein TusA family
Q433_RS13105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_RS13105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q433_RS13115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q433_RS13115	COG0425	Belongs to the sulfur carrier protein TusA family
Q433_RS13125	COG1937	Protein conserved in bacteria
Q433_RS13130	COG0662	Cupin 2, conserved barrel domain protein
Q433_RS13145	COG0789	Transcriptional regulator
Q433_RS13145	COG4978	Transcriptional regulator
Q433_RS13150	COG2814	Major facilitator Superfamily
Q433_RS13155	COG0456	acetyltransferase
Q433_RS13160	COG1253	flavin adenine dinucleotide binding
Q433_RS13170	COG0697	spore germination
Q433_RS13175	COG0583	DNA-binding transcription factor activity
Q433_RS13180	COG2072	flavoprotein involved in K transport
Q433_RS13185	COG1230	cation diffusion facilitator family transporter
Q433_RS13190	COG1942	4-Oxalocrotonate Tautomerase
Q433_RS13195	COG0583	DNA-binding transcription factor activity
Q433_RS13210	COG1687	branched-chain amino acid
Q433_RS13215	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Q433_RS13220	COG1522	sequence-specific DNA binding
Q433_RS13230	COG2124	cytochrome p450
Q433_RS13245	COG1335	isochorismatase
Q433_RS13255	COG2318	DinB family
Q433_RS13265	COG2070	2-Nitropropane dioxygenase
Q433_RS13270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Q433_RS13280	COG2186	Transcriptional regulator
Q433_RS13290	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS13295	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Q433_RS13300	COG3959	Transketolase, thiamine diphosphate binding domain
Q433_RS13310	COG0789	Transcriptional regulator
Q433_RS13310	COG4978	Transcriptional regulator
Q433_RS13315	COG2315	Protein conserved in bacteria
Q433_RS13325	COG3443	Belongs to the bacterial solute-binding protein 9 family
Q433_RS13330	COG1595	DNA-templated transcription, initiation
Q433_RS13335	COG0667	Aldo Keto reductase
Q433_RS13340	COG2851	Citrate transporter
Q433_RS13345	COG0583	DNA-binding transcription factor activity
Q433_RS13350	COG2828	Protein conserved in bacteria
Q433_RS13355	COG3409	Peptidoglycan-binding domain 1 protein
Q433_RS13360	COG5566	PFAM Mor transcription activator
Q433_RS13365	COG0596	Alpha beta hydrolase
Q433_RS13370	COG4991	sh3 domain protein
Q433_RS13375	COG4991	sh3 domain protein
Q433_RS13380	COG0346	lactoylglutathione lyase activity
Q433_RS13390	COG5577	PFAM Coat F domain
Q433_RS13395	COG1063	alcohol dehydrogenase
Q433_RS13405	COG5577	PFAM Coat F domain
Q433_RS13410	COG0789	Transcriptional regulator
Q433_RS13415	COG1064	alcohol dehydrogenase
Q433_RS13420	COG0693	protein deglycase activity
Q433_RS13425	COG1621	beta-fructofuranosidase activity
Q433_RS13430	COG3716	PTS system mannose fructose sorbose family IID component
Q433_RS13435	COG3715	PTS system
Q433_RS13440	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_RS13445	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_RS13450	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Q433_RS13450	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Q433_RS13455	COG1113	amino acid transport
Q433_RS13460	COG1280	lysine exporter protein (LysE YggA)
Q433_RS13465	COG1378	Sugar-specific transcriptional regulator TrmB
Q433_RS13470	COG1595	DNA-templated transcription, initiation
Q433_RS13490	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Q433_RS13490	COG2124	cytochrome p450
Q433_RS13495	COG1309	transcriptional regulator
Q433_RS13500	COG2226	methyltransferase
Q433_RS13515	COG2116	formate transmembrane transporter activity
Q433_RS13520	COG5609	conserved protein (DUF2294)
Q433_RS13525	COG3383	formate dehydrogenase (NAD+) activity
Q433_RS13530	COG2427	Protein of unknown function (DUF1641)
Q433_RS13540	COG0626	cystathionine gamma-synthase activity
Q433_RS13545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Q433_RS13550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Q433_RS13555	COG2226	methyltransferase
Q433_RS13570	COG0768	penicillin binding
Q433_RS13575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Q433_RS13580	COG0572	uridine kinase
Q433_RS13595	COG4122	O-methyltransferase activity
Q433_RS13600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Q433_RS13605	COG3906	Belongs to the UPF0473 family
Q433_RS13610	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Q433_RS13615	COG4472	Bacterial protein of unknown function (DUF965)
Q433_RS13620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Q433_RS13625	COG0628	permease
Q433_RS13630	COG1126	abc transporter atp-binding protein
Q433_RS13635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_RS13640	COG0765	amino acid transport
Q433_RS13645	COG0765	amino acid transport
Q433_RS13660	COG3881	PFAM PRC-barrel domain
Q433_RS13665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Q433_RS13670	COG0457	Tetratricopeptide repeat
Q433_RS13675	COG0482	sulfurtransferase activity
Q433_RS13680	COG1104	cysteine desulfurase activity
Q433_RS13685	COG1959	2 iron, 2 sulfur cluster binding
Q433_RS13690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Q433_RS13695	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Q433_RS13705	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Q433_RS13710	COG0124	histidyl-tRNA synthetase
Q433_RS13720	COG4991	sh3 domain protein
Q433_RS13720	COG3103	Sh3 type 3 domain protein
Q433_RS13720	COG0860	N-Acetylmuramoyl-L-alanine amidase
Q433_RS13725	COG1490	D-aminoacyl-tRNA deacylase activity
Q433_RS13730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Q433_RS13735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Q433_RS13740	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Q433_RS13740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Q433_RS13745	COG5416	Lipopolysaccharide assembly protein A domain
Q433_RS13750	COG0490	domain, Protein
Q433_RS13755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Q433_RS13755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Q433_RS13765	COG2244	polysaccharide biosynthetic process
Q433_RS13770	COG2323	membrane
Q433_RS13780	COG1862	Preprotein translocase
Q433_RS13785	COG0343	queuine tRNA-ribosyltransferase activity
Q433_RS13790	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Q433_RS13800	COG2255	four-way junction helicase activity
Q433_RS13805	COG0632	four-way junction helicase activity
Q433_RS13815	COG2814	Major facilitator Superfamily
Q433_RS13820	COG0673	inositol 2-dehydrogenase activity
Q433_RS13825	COG2112	serine threonine protein kinase
Q433_RS13845	COG1115	amino acid carrier protein
Q433_RS13850	COG0217	transcriptional regulatory protein
Q433_RS13860	COG1388	LysM domain
Q433_RS13865	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Q433_RS13870	COG0157	Belongs to the NadC ModD family
Q433_RS13875	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Q433_RS13880	COG1104	cysteine desulfurase activity
Q433_RS13885	COG1827	regulation of RNA biosynthetic process
Q433_RS13890	COG0077	Prephenate dehydratase
Q433_RS13895	COG4492	Belongs to the UPF0735 family
Q433_RS13900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Q433_RS13905	COG3290	protein histidine kinase activity
Q433_RS13915	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Q433_RS13920	COG2868	ribosomal protein
Q433_RS13925	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Q433_RS13930	COG1994	Peptidase M50
Q433_RS13935	COG0739	heme binding
Q433_RS13940	COG2894	cell division
Q433_RS13945	COG0850	regulation of cytokinetic process
Q433_RS13950	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Q433_RS13960	COG1077	Cell shape determining protein MreB Mrl
Q433_RS13965	COG2003	Belongs to the UPF0758 family
Q433_RS13970	COG0424	maF-like protein
Q433_RS13980	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Q433_RS13985	COG0285	dihydrofolate synthase activity
Q433_RS13990	COG0525	valine-tRNA ligase activity
Q433_RS14000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Q433_RS14005	COG1388	LysM domain
Q433_RS14010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Q433_RS14015	COG0113	porphobilinogen synthase activity
Q433_RS14020	COG1587	Uroporphyrinogen-III synthase
Q433_RS14025	COG0181	hydroxymethylbilane synthase activity
Q433_RS14030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Q433_RS14035	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Q433_RS14045	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Q433_RS14050	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Q433_RS14055	COG0470	DNA polymerase III
Q433_RS14055	COG1067	ATP-dependent peptidase activity
Q433_RS14060	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Q433_RS14065	COG0544	peptidyl-prolyl cis-trans isomerase activity
Q433_RS14070	COG1477	protein flavinylation
Q433_RS14070	COG0457	Tetratricopeptide repeat
Q433_RS14075	COG0066	3-isopropylmalate dehydratase activity
Q433_RS14080	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Q433_RS14085	COG0473	3-isopropylmalate dehydrogenase activity
Q433_RS14090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Q433_RS14095	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Q433_RS14100	COG0440	acetolactate synthase activity
Q433_RS14105	COG0028	Belongs to the TPP enzyme family
Q433_RS14115	COG0454	-acetyltransferase
Q433_RS14125	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
Q433_RS14135	COG0622	Phosphoesterase
Q433_RS14140	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Q433_RS14145	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Q433_RS14150	COG5401	PFAM Sporulation and spore germination
Q433_RS14155	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Q433_RS14160	COG1846	Transcriptional regulator
Q433_RS14165	COG2197	response regulator
Q433_RS14170	COG0824	Thioesterase
Q433_RS14175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Q433_RS14180	COG1053	succinate dehydrogenase
Q433_RS14185	COG2009	succinate dehydrogenase
Q433_RS14195	COG1719	4-vinyl reductase, 4VR
Q433_RS14200	COG0527	aspartate kinase activity
Q433_RS14205	COG0322	excinuclease ABC activity
Q433_RS14210	COG3118	belongs to the thioredoxin family
Q433_RS14215	COG3534	alpha-L-arabinofuranosidase
Q433_RS14220	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Q433_RS14225	COG2086	electron transfer activity
Q433_RS14230	COG1024	Enoyl-CoA hydratase
Q433_RS14235	COG1309	transcriptional regulator
Q433_RS14240	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_RS14245	COG3766	membrane
Q433_RS14250	COG1193	negative regulation of DNA recombination
Q433_RS14255	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Q433_RS14255	COG1796	DNA polymerase
Q433_RS14260	COG1286	toxin biosynthetic process
Q433_RS14265	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
Q433_RS14270	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Q433_RS14275	COG0072	phenylalanine-tRNA ligase activity
Q433_RS14275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q433_RS14280	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Q433_RS14290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Q433_RS14300	COG3835	regulator
Q433_RS14305	COG0277	FAD linked oxidase domain protein
Q433_RS14310	COG0247	lactate metabolic process
Q433_RS14315	COG0346	lactoylglutathione lyase activity
Q433_RS14325	COG1966	Carbon starvation protein
Q433_RS14330	COG3534	alpha-L-arabinofuranosidase
Q433_RS14335	COG0395	ABC-type sugar transport system, permease component
Q433_RS14340	COG1175	transmembrane transport
Q433_RS14345	COG1653	transport
Q433_RS14350	COG0371	Dehydrogenase
Q433_RS14355	COG0647	UMP catabolic process
Q433_RS14360	COG0235	Class ii aldolase
Q433_RS14365	COG1069	ribulokinase activity
Q433_RS14370	COG2160	L-arabinose isomerase activity
Q433_RS14375	COG3507	Belongs to the glycosyl hydrolase 43 family
Q433_RS14380	COG1363	Peptidase, m42
Q433_RS14390	COG3326	Membrane
Q433_RS14395	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Q433_RS14400	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Q433_RS14405	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Q433_RS14415	COG1346	cytolysis
Q433_RS14420	COG1380	Effector of murein hydrolase LrgA
Q433_RS14425	COG3279	Response regulator of the LytR AlgR family
Q433_RS14430	COG3275	phosphorelay sensor kinase activity
Q433_RS14435	COG1011	Hydrolase
Q433_RS14440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Q433_RS14450	COG0398	Pfam SNARE associated Golgi protein
Q433_RS14455	COG1484	DNA-dependent DNA replication
Q433_RS14460	COG3611	Membrane attachment protein
Q433_RS14465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Q433_RS14470	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Q433_RS14475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Q433_RS14480	COG1733	regulation of RNA biosynthetic process
Q433_RS14485	COG2814	Major facilitator Superfamily
Q433_RS14490	COG0656	L-ascorbic acid biosynthetic process
Q433_RS14495	COG0237	dephospho-CoA kinase activity
Q433_RS14510	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Q433_RS14515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q433_RS14515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q433_RS14520	COG5002	protein histidine kinase activity
Q433_RS14525	COG0745	RESPONSE REGULATOR receiver
Q433_RS14530	COG0039	L-malate dehydrogenase activity
Q433_RS14535	COG0538	isocitrate dehydrogenase activity
Q433_RS14540	COG0372	Belongs to the citrate synthase family
Q433_RS14545	COG2707	UPF0756 membrane protein
Q433_RS14550	COG0628	permease
Q433_RS14555	COG3030	protein affecting phage T7 exclusion by the F plasmid
Q433_RS14560	COG0469	pyruvate kinase activity
Q433_RS14565	COG0205	6-phosphofructokinase activity
Q433_RS14570	COG0825	malonyl-CoA metabolic process
Q433_RS14575	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Q433_RS14580	COG0281	malic enzyme
Q433_RS14585	COG0587	DNA-directed DNA polymerase activity
Q433_RS14605	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Q433_RS14615	COG4109	DRTGG domain
Q433_RS14625	COG0730	response to heat
Q433_RS14630	COG1473	amidohydrolase
Q433_RS14635	COG0196	riboflavin kinase activity
Q433_RS14640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Q433_RS14645	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Q433_RS14650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Q433_RS14655	COG1126	abc transporter atp-binding protein
Q433_RS14660	COG0765	amino acid transport
Q433_RS14665	COG0765	amino acid transport
Q433_RS14670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_RS14675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_RS14680	COG0454	-acetyltransferase
Q433_RS14685	COG0583	DNA-binding transcription factor activity
Q433_RS14690	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Q433_RS14695	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS14705	COG0165	Argininosuccinate lyase
Q433_RS14710	COG0137	argininosuccinate synthase activity
Q433_RS14715	COG0521	Mo-molybdopterin cofactor biosynthetic process
Q433_RS14720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Q433_RS14725	COG0827	DNA restriction-modification system
Q433_RS14730	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Q433_RS14735	COG3874	Sporulation protein YtfJ
Q433_RS14745	COG1714	RDD family
Q433_RS14750	COG0616	signal peptide processing
Q433_RS14755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Q433_RS14760	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Q433_RS14765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Q433_RS14775	COG0301	tRNA thio-modification
Q433_RS14780	COG1104	cysteine desulfurase activity
Q433_RS14785	COG1114	Component of the transport system for branched-chain amino acids
Q433_RS14790	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
Q433_RS14795	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Q433_RS14800	COG1309	transcriptional regulator
Q433_RS14805	COG1956	GAF domain-containing protein
Q433_RS14810	COG2199	diguanylate cyclase activity
Q433_RS14810	COG2203	Gaf domain
Q433_RS14815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Q433_RS14825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Q433_RS14830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Q433_RS14835	COG0454	-acetyltransferase
Q433_RS14840	COG0517	IMP dehydrogenase activity
Q433_RS14845	COG0123	including yeast histone deacetylase and acetoin utilization protein
Q433_RS14850	COG1360	Flagellar Motor Protein
Q433_RS14855	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Q433_RS14860	COG1609	Transcriptional regulator
Q433_RS14865	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Q433_RS14865	COG1605	Chorismate mutase
Q433_RS14870	COG3118	belongs to the thioredoxin family
Q433_RS14875	COG4980	gas vesicle protein
Q433_RS14880	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
Q433_RS14885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Q433_RS14890	COG1674	ftsk spoiiie
Q433_RS14895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q433_RS14900	COG4848	Belongs to the UPF0354 family
Q433_RS14905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_RS14915	COG1363	Peptidase, m42
Q433_RS14920	COG5584	Small secreted protein
Q433_RS14925	COG0281	malic enzyme
Q433_RS14930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_RS14935	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Q433_RS14945	COG0510	thiamine kinase activity
Q433_RS14950	COG1523	belongs to the glycosyl hydrolase 13 family
Q433_RS14955	COG1597	lipid kinase activity
Q433_RS14965	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Q433_RS14970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Q433_RS14975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q433_RS14980	COG2252	PERMEase
Q433_RS14985	COG4473	ABC transporter
Q433_RS14990	COG1131	(ABC) transporter
Q433_RS14995	COG1349	DNA-binding transcription factor activity
Q433_RS15000	COG1187	pseudouridine synthase activity
Q433_RS15005	COG2244	polysaccharide biosynthetic process
Q433_RS15010	COG2081	HI0933 family
Q433_RS15015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Q433_RS15025	COG5578	integral membrane protein
Q433_RS15030	COG0673	inositol 2-dehydrogenase activity
Q433_RS15035	COG1653	transport
Q433_RS15040	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Q433_RS15045	COG4209	transmembrane transport
Q433_RS15050	COG2207	Transcriptional regulator
Q433_RS15055	COG1653	transport
Q433_RS15060	COG0395	ABC-type sugar transport system, permease component
Q433_RS15065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q433_RS15070	COG2124	cytochrome p450
Q433_RS15075	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Q433_RS15085	COG0156	8-amino-7-oxononanoate synthase activity
Q433_RS15090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Q433_RS15100	COG1073	alpha beta
Q433_RS15105	COG1609	Transcriptional regulator
Q433_RS15110	COG1653	transport
Q433_RS15115	COG1175	transmembrane transport
Q433_RS15120	COG0395	ABC-type sugar transport system, permease component
Q433_RS15125	COG1486	melibiose metabolic process
Q433_RS15130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q433_RS15135	COG0495	leucyl-tRNA aminoacylation
Q433_RS15145	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_RS15145	COG2202	Pas domain
Q433_RS15150	COG2814	Major facilitator Superfamily
Q433_RS15155	COG2433	Pfam Transposase IS66
Q433_RS15160	COG0577	efflux transmembrane transporter activity
Q433_RS15165	COG1136	(ABC) transporter
Q433_RS15170	COG2205	protein histidine kinase activity
Q433_RS15175	COG0745	RESPONSE REGULATOR receiver
Q433_RS15180	COG0577	efflux transmembrane transporter activity
Q433_RS15185	COG1136	(ABC) transporter
Q433_RS15200	COG1131	(ABC) transporter
Q433_RS15205	COG1725	Transcriptional regulator
Q433_RS15220	COG1242	4 iron, 4 sulfur cluster binding
Q433_RS15225	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Q433_RS15235	COG2267	carboxylic ester hydrolase activity
Q433_RS15240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Q433_RS15245	COG1113	amino acid transport
Q433_RS15250	COG0367	asparagine synthase
Q433_RS15255	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Q433_RS15260	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Q433_RS15270	COG1506	peptidase
Q433_RS15275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Q433_RS15280	COG1116	anion transmembrane transporter activity
Q433_RS15285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q433_RS15290	COG0494	nUDIX hydrolase
Q433_RS15295	COG4824	toxin secretion phage lysis holin
Q433_RS15300	COG0783	Belongs to the Dps family
Q433_RS15315	COG1854	S-ribosylhomocysteine lyase activity
Q433_RS15320	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Q433_RS15325	COG0288	reversible hydration of carbon dioxide
Q433_RS15330	COG0254	rRNA binding
Q433_RS15335	COG1271	oxidase subunit
Q433_RS15340	COG1294	oxidase, subunit
Q433_RS15350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Q433_RS15355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Q433_RS15355	COG1321	iron dependent repressor
Q433_RS15360	COG1121	(ABC) transporter
Q433_RS15365	COG0803	Belongs to the bacterial solute-binding protein 9 family
Q433_RS15370	COG4948	Mandelate Racemase Muconate Lactonizing
Q433_RS15375	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_RS15380	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Q433_RS15385	COG0596	Alpha beta hydrolase
Q433_RS15390	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Q433_RS15395	COG1169	isochorismate synthase
Q433_RS15400	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Q433_RS15405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Q433_RS15410	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Q433_RS15415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q433_RS15420	COG0438	transferase activity, transferring glycosyl groups
Q433_RS15430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Q433_RS15435	COG0438	transferase activity, transferring glycosyl groups
Q433_RS15440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Q433_RS15445	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Q433_RS15450	COG0058	SHG alpha-glucan phosphorylase activity
Q433_RS15455	COG0297	glycogen (starch) synthase activity
Q433_RS15460	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Q433_RS15465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Q433_RS15470	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Q433_RS15600	COG3859	Proton-coupled thiamine transporter YuaJ
Q433_RS15605	COG1247	-acetyltransferase
Q433_RS15610	COG2268	Band 7 protein
Q433_RS15615	COG1585	Membrane protein implicated in regulation of membrane protease activity
Q433_RS15620	COG2318	DinB family
Q433_RS15630	COG1454	alcohol dehydrogenase
Q433_RS15635	COG1012	belongs to the aldehyde dehydrogenase family
Q433_RS15640	COG1510	regulation of RNA biosynthetic process
Q433_RS15650	COG0569	domain protein
Q433_RS15655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Q433_RS15660	COG4682	membrane
Q433_RS15665	COG1705	Flagellar rod assembly protein muramidase FlgJ
Q433_RS15670	COG0477	Major facilitator Superfamily
Q433_RS15675	COG5553	Cysteine dioxygenase type I
Q433_RS15685	COG1968	undecaprenyl-diphosphatase activity
Q433_RS15690	COG0628	permease
Q433_RS15695	COG0673	inositol 2-dehydrogenase activity
Q433_RS15700	COG4806	L-rhamnose isomerase
Q433_RS15705	COG3254	rhamnose metabolic process
Q433_RS15710	COG1070	Carbohydrate kinase
Q433_RS15715	COG1349	DNA-binding transcription factor activity
Q433_RS15720	COG3347	Dehydrogenase
Q433_RS15720	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS15730	COG0840	transmembrane signaling receptor activity
Q433_RS15735	COG0840	transmembrane signaling receptor activity
Q433_RS15740	COG0840	transmembrane signaling receptor activity
Q433_RS15745	COG0840	transmembrane signaling receptor activity
Q433_RS15760	COG0432	Pfam Uncharacterised protein family UPF0047
Q433_RS15765	COG0366	Alpha amylase catalytic
Q433_RS15770	COG1253	flavin adenine dinucleotide binding
Q433_RS15775	COG2738	Putative neutral zinc metallopeptidase
Q433_RS15790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Q433_RS15805	COG0166	Belongs to the GPI family
Q433_RS15810	COG1979	alcohol dehydrogenase
Q433_RS15815	COG1979	alcohol dehydrogenase
Q433_RS15820	COG2155	Conserved Protein
Q433_RS15825	COG1098	S1 RNA binding domain
Q433_RS15830	COG0436	Aminotransferase
Q433_RS15835	COG1522	sequence-specific DNA binding
Q433_RS15840	COG2267	carboxylic ester hydrolase activity
Q433_RS15850	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Q433_RS15855	COG2205	protein histidine kinase activity
Q433_RS15865	COG5018	Exonuclease
Q433_RS15875	COG2814	Major facilitator Superfamily
Q433_RS15880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Q433_RS15885	COG3011	Protein conserved in bacteria
Q433_RS15900	COG4565	transcriptional regulatory protein
Q433_RS15925	COG3493	citrate carrier protein
Q433_RS15935	COG2111	Na H antiporter
Q433_RS15935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Q433_RS15940	COG2111	Na H antiporter
Q433_RS15945	COG1006	Multisubunit Na H antiporter MnhC subunit
Q433_RS15950	COG0651	ATP synthesis coupled electron transport
Q433_RS15955	COG1863	multisubunit Na H antiporter MnhE subunit
Q433_RS15960	COG2212	antiporter activity
Q433_RS15965	COG1320	monovalent cation:proton antiporter activity
Q433_RS15970	COG2050	protein possibly involved in aromatic compounds catabolism
Q433_RS15975	COG2197	response regulator
Q433_RS15980	COG4585	Histidine kinase
Q433_RS15990	COG0142	geranyltranstransferase activity
Q433_RS16005	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Q433_RS16010	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Q433_RS16015	COG1335	isochorismatase
Q433_RS16020	COG5506	Protein of unknown function (DUF1694)
Q433_RS16035	COG0628	permease
Q433_RS16050	COG1418	mRNA catabolic process
Q433_RS16055	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS16065	COG1511	domain protein
Q433_RS16070	COG1674	ftsk spoiiie
Q433_RS16070	COG0433	COG0433 Predicted ATPase
Q433_RS16075	COG4499	WXG100 protein secretion system (Wss), protein YukC
Q433_RS16080	COG5417	Belongs to the EsaB family
Q433_RS16085	COG4842	Belongs to the WXG100 family
Q433_RS16090	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Q433_RS16090	COG2508	Transcriptional regulator
Q433_RS16095	COG0686	Belongs to the AlaDH PNT family
Q433_RS16100	COG5634	Uncharacterized conserved protein (DUF2278)
Q433_RS16105	COG3251	PFAM MbtH domain protein
Q433_RS16110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_RS16115	COG1535	isochorismatase
Q433_RS16115	COG3433	isochorismatase activity
Q433_RS16120	COG1021	2,3-dihydroxybenzoate-AMP ligase
Q433_RS16125	COG1169	isochorismate synthase
Q433_RS16130	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS16135	COG2819	hydrolase of the alpha beta superfamily
Q433_RS16140	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Q433_RS16145	COG1268	BioY protein
Q433_RS16150	COG2056	Na+-H+ antiporter family
Q433_RS16155	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Q433_RS16160	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
Q433_RS16165	COG3584	3D domain protein
Q433_RS16180	COG1252	NADH dehydrogenase
Q433_RS16185	COG0492	ferredoxin-NADP+ reductase activity
Q433_RS16195	COG0516	GMP reductase activity
Q433_RS16200	COG2808	Putative FMN-binding domain
Q433_RS16205	COG0456	acetyltransferase
Q433_RS16210	COG0316	Belongs to the HesB IscA family
Q433_RS16215	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Q433_RS16220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Q433_RS16225	COG4844	belongs to the
Q433_RS16230	COG1252	NADH dehydrogenase
Q433_RS16235	COG4837	Protein of unknown function (DUF1462)
Q433_RS16240	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Q433_RS16245	COG4946	Tricorn protease homolog
Q433_RS16245	COG1506	peptidase
Q433_RS16245	COG0823	Involved in the tonB-independent uptake of proteins
Q433_RS16250	COG0083	homoserine kinase activity
Q433_RS16255	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Q433_RS16260	COG0460	homoserine dehydrogenase
Q433_RS16265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Q433_RS16270	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Q433_RS16275	COG0647	UMP catabolic process
Q433_RS16280	COG2445	Protein of unknown function DUF86
Q433_RS16285	COG4470	Protein conserved in bacteria
Q433_RS16295	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Q433_RS16300	COG0739	heme binding
Q433_RS16310	COG3377	Domain of unknown function (DUF1805)
Q433_RS16315	COG0737	Belongs to the 5'-nucleotidase family
Q433_RS16320	COG0730	response to heat
Q433_RS16325	COG1801	Protein of unknown function DUF72
Q433_RS16335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Q433_RS16340	COG2508	Transcriptional regulator
Q433_RS16345	COG2233	PERMEase
Q433_RS16350	COG2233	PERMEase
Q433_RS16355	COG3648	Uricase
Q433_RS16355	COG3195	allantoin biosynthetic process
Q433_RS16360	COG2351	hydroxyisourate hydrolase activity
Q433_RS16370	COG2080	2 iron, 2 sulfur cluster binding
Q433_RS16375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Q433_RS16380	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Q433_RS16385	COG2068	MobA-Related Protein
Q433_RS16390	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Q433_RS16395	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Q433_RS16400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q433_RS16410	COG2356	endonuclease I
Q433_RS16415	COG3842	ATPase activity
Q433_RS16420	COG2188	Transcriptional regulator
Q433_RS16425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q433_RS16430	COG0395	ABC-type sugar transport system, permease component
Q433_RS16435	COG1175	transmembrane transport
Q433_RS16440	COG1653	transport
Q433_RS16445	COG2222	sugar isomerase
Q433_RS16450	COG0322	excinuclease ABC activity
Q433_RS16455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q433_RS16470	COG0346	lactoylglutathione lyase activity
Q433_RS16475	COG0640	Transcriptional regulator
Q433_RS16480	COG0719	Fe-S assembly protein
Q433_RS16485	COG0822	iron-sulfur transferase activity
Q433_RS16490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Q433_RS16495	COG0719	Fe-S assembly protein
Q433_RS16500	COG0396	ATPase activity
Q433_RS16510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Q433_RS16515	COG1464	Belongs to the NlpA lipoprotein family
Q433_RS16520	COG2011	ABC-type metal ion transport system permease component
Q433_RS16525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Q433_RS16535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_RS16540	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
Q433_RS16550	COG0509	glycine decarboxylation via glycine cleavage system
Q433_RS16555	COG1393	Belongs to the ArsC family
Q433_RS16560	COG1960	acyl-CoA dehydrogenase activity
Q433_RS16565	COG0183	Belongs to the thiolase family
Q433_RS16570	COG1024	Enoyl-CoA hydratase
Q433_RS16570	COG1250	3-hydroxyacyl-CoA dehydrogenase
Q433_RS16580	COG0506	proline dehydrogenase activity
Q433_RS16590	COG5577	PFAM Coat F domain
Q433_RS16595	COG1846	Transcriptional regulator
Q433_RS16600	COG0477	Major facilitator Superfamily
Q433_RS16605	COG1942	4-Oxalocrotonate Tautomerase
Q433_RS16610	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS16615	COG0583	DNA-binding transcription factor activity
Q433_RS16625	COG1120	ATPase activity
Q433_RS16640	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS16645	COG0783	Belongs to the Dps family
Q433_RS16650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q433_RS16660	COG2205	protein histidine kinase activity
Q433_RS16660	COG2770	Histidine kinase
Q433_RS16670	COG1309	transcriptional regulator
Q433_RS16675	COG0114	fumarate hydratase activity
Q433_RS16685	COG0697	spore germination
Q433_RS16690	COG0814	amino acid
Q433_RS16700	COG2197	response regulator
Q433_RS16705	COG4585	Histidine kinase
Q433_RS16710	COG4758	membrane
Q433_RS16715	COG3595	metallopeptidase activity
Q433_RS16720	COG1842	Phage shock protein A
Q433_RS16725	COG4758	membrane
Q433_RS16730	COG2814	Major facilitator Superfamily
Q433_RS16735	COG2096	Adenosyltransferase
Q433_RS16740	COG1120	ATPase activity
Q433_RS16745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_RS16750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Q433_RS16760	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS16765	COG3386	PFAM SMP-30 Gluconolaconase
Q433_RS16770	COG2205	protein histidine kinase activity
Q433_RS16775	COG0745	RESPONSE REGULATOR receiver
Q433_RS16785	COG1191	sigma factor activity
Q433_RS16795	COG2140	Oxalate decarboxylase
Q433_RS16805	COG0577	efflux transmembrane transporter activity
Q433_RS16810	COG1136	(ABC) transporter
Q433_RS16815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q433_RS16820	COG1120	ATPase activity
Q433_RS16825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_RS16830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_RS16835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Q433_RS16845	COG0531	amino acid
Q433_RS16855	COG1988	membrane-bound metal-dependent
Q433_RS16860	COG1368	sulfuric ester hydrolase activity
Q433_RS16865	COG1910	domain protein
Q433_RS16870	COG0725	ABC transporter, periplasmic molybdate-binding protein
Q433_RS16875	COG4149	molybdate abc transporter
Q433_RS16880	COG0656	L-ascorbic acid biosynthetic process
Q433_RS16890	COG0025	NhaP-type Na H and K H
Q433_RS16895	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Q433_RS16900	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Q433_RS16905	COG3973	AAA domain
Q433_RS16915	COG2860	membrane
Q433_RS16920	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Q433_RS16925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Q433_RS16930	COG2217	Heavy metal translocating P-type atpase
Q433_RS16935	COG2217	Heavy metal translocating P-type atpase
Q433_RS16940	COG2608	mercury ion transmembrane transporter activity
Q433_RS16945	COG1937	Protein conserved in bacteria
Q433_RS16950	COG0673	inositol 2-dehydrogenase activity
Q433_RS16955	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Q433_RS16960	COG1289	transmembrane transporter activity
Q433_RS16970	COG2076	Multidrug Resistance protein
Q433_RS16975	COG1309	transcriptional regulator
Q433_RS16980	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS16985	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Q433_RS16990	COG0557	exoribonuclease II activity
Q433_RS16995	COG1647	Serine aminopeptidase, S33
Q433_RS17000	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Q433_RS17005	COG0596	Alpha beta hydrolase
Q433_RS17010	COG1476	TRANSCRIPTIONal
Q433_RS17015	COG1396	sequence-specific DNA binding
Q433_RS17020	COG1396	sequence-specific DNA binding
Q433_RS17025	COG1733	regulation of RNA biosynthetic process
Q433_RS17030	COG0840	transmembrane signaling receptor activity
Q433_RS17035	COG1174	glycine betaine transport
Q433_RS17040	COG1732	Glycine betaine
Q433_RS17045	COG1174	glycine betaine transport
Q433_RS17050	COG0517	IMP dehydrogenase activity
Q433_RS17050	COG1125	glycine betaine transport
Q433_RS17055	COG1510	regulation of RNA biosynthetic process
Q433_RS17060	COG1174	glycine betaine transport
Q433_RS17065	COG1732	Glycine betaine
Q433_RS17070	COG1174	glycine betaine transport
Q433_RS17075	COG0517	IMP dehydrogenase activity
Q433_RS17075	COG1125	glycine betaine transport
Q433_RS17080	COG1510	regulation of RNA biosynthetic process
Q433_RS17085	COG2095	MarC family integral membrane protein
Q433_RS17095	COG3064	Membrane
Q433_RS17100	COG4640	response to antibiotic
Q433_RS17105	COG0456	acetyltransferase
Q433_RS17110	COG0148	phosphopyruvate hydratase activity
Q433_RS17115	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Q433_RS17120	COG0149	triose-phosphate isomerase activity
Q433_RS17125	COG0126	phosphoglycerate kinase activity
Q433_RS17135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Q433_RS17140	COG2390	Transcriptional regulator
Q433_RS17145	COG2814	Major facilitator Superfamily
Q433_RS17150	COG1609	Transcriptional regulator
Q433_RS17155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Q433_RS17165	COG0583	DNA-binding transcription factor activity
Q433_RS17170	COG0697	spore germination
Q433_RS17175	COG1113	amino acid transport
Q433_RS17180	COG3858	chitin binding
Q433_RS17185	COG1556	Lactate utilization protein
Q433_RS17190	COG1139	Iron-sulfur cluster binding protein
Q433_RS17195	COG0247	lactate metabolic process
Q433_RS17200	COG2197	response regulator
Q433_RS17205	COG4585	Histidine kinase
Q433_RS17210	COG0842	Transport permease protein
Q433_RS17215	COG1131	(ABC) transporter
Q433_RS17220	COG0596	Alpha beta hydrolase
Q433_RS17225	COG2208	phosphoserine phosphatase activity
Q433_RS17230	COG3867	Arabinogalactan endo-beta-1,4-galactanase
Q433_RS17235	COG1874	Beta-galactosidase
Q433_RS17240	COG3833	ABC-type maltose transport systems, permease component
Q433_RS17245	COG1175	transmembrane transport
Q433_RS17250	COG2182	Extracellular solute-binding protein
Q433_RS17255	COG1609	Transcriptional regulator
Q433_RS17260	COG2186	Transcriptional regulator
Q433_RS17265	COG1620	l-lactate permease
Q433_RS17270	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Q433_RS17280	COG5039	Polysaccharide pyruvyl transferase
Q433_RS17285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Q433_RS17290	COG0110	maltose O-acetyltransferase activity
Q433_RS17295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Q433_RS17300	COG2244	polysaccharide biosynthetic process
Q433_RS17305	COG1216	Glycosyl transferase, family 2
Q433_RS17310	COG5039	Polysaccharide pyruvyl transferase
Q433_RS17315	COG1216	Glycosyl transferase, family 2
Q433_RS17325	COG0438	transferase activity, transferring glycosyl groups
Q433_RS17330	COG1215	transferase activity, transferring glycosyl groups
Q433_RS17335	COG0438	transferase activity, transferring glycosyl groups
Q433_RS17340	COG1086	Polysaccharide biosynthesis protein
Q433_RS17345	COG0489	protein tyrosine kinase activity
Q433_RS17350	COG3944	biosynthesis protein
Q433_RS17355	COG1396	sequence-specific DNA binding
Q433_RS17360	COG2272	Belongs to the type-B carboxylesterase lipase family
Q433_RS17370	COG3479	Phenolic acid decarboxylase
Q433_RS17380	COG1794	racemase activity, acting on amino acids and derivatives
Q433_RS17385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Q433_RS17390	COG1621	beta-fructofuranosidase activity
Q433_RS17395	COG1621	beta-fructofuranosidase activity
Q433_RS17400	COG0531	amino acid
Q433_RS17405	COG1309	transcriptional regulator
Q433_RS17410	COG2076	Multidrug Resistance protein
Q433_RS17415	COG2076	Multidrug Resistance protein
Q433_RS17425	COG0277	FAD linked oxidase domain protein
Q433_RS17430	COG3621	Patatin-like phospholipase
Q433_RS17440	COG0740	serine-type endopeptidase activity
Q433_RS17445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Q433_RS17450	COG0366	Alpha amylase catalytic
Q433_RS17455	COG1554	hydrolase, family 65, central catalytic
Q433_RS17460	COG5521	maltodextrose utilization protein MalA
Q433_RS17465	COG3833	ABC-type maltose transport systems, permease component
Q433_RS17470	COG1175	transmembrane transport
Q433_RS17475	COG2182	Extracellular solute-binding protein
Q433_RS17480	COG0366	Alpha amylase catalytic
Q433_RS17485	COG1609	Transcriptional regulator
Q433_RS17490	COG1611	Belongs to the LOG family
Q433_RS17495	COG1694	Mazg nucleotide pyrophosphohydrolase
Q433_RS17500	COG0659	secondary active sulfate transmembrane transporter activity
Q433_RS17505	COG0288	reversible hydration of carbon dioxide
Q433_RS17510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Q433_RS17515	COG0577	efflux transmembrane transporter activity
Q433_RS17520	COG1136	(ABC) transporter
Q433_RS17525	COG5002	protein histidine kinase activity
Q433_RS17530	COG0745	RESPONSE REGULATOR receiver
Q433_RS17540	COG2162	N-hydroxyarylamine O-acetyltransferase activity
Q433_RS17545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_RS17550	COG1481	regulation of sporulation
Q433_RS17555	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Q433_RS17560	COG1660	Displays ATPase and GTPase activities
Q433_RS17565	COG1051	belongs to the nudix hydrolase family
Q433_RS17570	COG0492	ferredoxin-NADP+ reductase activity
Q433_RS17575	COG3883	PFAM NLP P60 protein
Q433_RS17575	COG0791	NLP P60 protein
Q433_RS17580	COG0457	Tetratricopeptide repeat
Q433_RS17585	COG1132	(ABC) transporter
Q433_RS17605	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Q433_RS17605	COG0140	phosphoribosyl-ATP diphosphatase activity
Q433_RS17610	COG0107	imidazoleglycerol-phosphate synthase activity
Q433_RS17615	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Q433_RS17620	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Q433_RS17625	COG0131	Imidazoleglycerol-phosphate dehydratase
Q433_RS17630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Q433_RS17635	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Q433_RS17640	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Q433_RS17645	COG4990	cell redox homeostasis
Q433_RS17650	COG5297	Belongs to the glycosyl hydrolase family 6
Q433_RS17655	COG0110	maltose O-acetyltransferase activity
Q433_RS17660	COG0546	phosphoglycolate phosphatase activity
Q433_RS17665	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Q433_RS17670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Q433_RS17675	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Q433_RS17680	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Q433_RS17685	COG0363	glucosamine-6-phosphate deaminase activity
Q433_RS17690	COG2188	Transcriptional regulator
Q433_RS17695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Q433_RS17700	COG1846	Transcriptional regulator
Q433_RS17705	COG2124	cytochrome p450
Q433_RS17715	COG1846	Transcriptional regulator
Q433_RS17720	COG2814	Major facilitator Superfamily
Q433_RS17725	COG1950	PFAM Membrane protein of
Q433_RS17730	COG1983	PspC domain protein
Q433_RS17735	COG3595	metallopeptidase activity
Q433_RS17750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Q433_RS17755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Q433_RS17760	COG0556	nucleotide-excision repair
Q433_RS17765	COG4897	Protein conserved in bacteria
Q433_RS17770	COG0574	Belongs to the PEP-utilizing enzyme family
Q433_RS17770	COG3848	Pyruvate phosphate dikinase
Q433_RS17775	COG1309	transcriptional regulator
Q433_RS17780	COG2814	Major facilitator Superfamily
Q433_RS17795	COG0793	Belongs to the peptidase S41A family
Q433_RS17795	COG3409	Peptidoglycan-binding domain 1 protein
Q433_RS17800	COG2177	Part of the ABC transporter FtsEX involved in
Q433_RS17805	COG2884	Cell division ATP-binding protein ftsE
Q433_RS17810	COG2010	Cytochrome c
Q433_RS17815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_RS17825	COG0653	protein targeting
Q433_RS17830	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Q433_RS17845	COG1516	flagellar protein fliS
Q433_RS17850	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Q433_RS17855	COG1334	flagellar protein FlaG
Q433_RS17860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Q433_RS17865	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q433_RS17870	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Q433_RS17880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Q433_RS17885	COG1256	bacterial-type flagellum assembly
Q433_RS17885	COG4786	Flagellar basal body rod
Q433_RS17890	COG3418	PFAM FlgN family protein
Q433_RS17895	COG2747	anti-sigma28 factor FlgM
Q433_RS17905	COG1040	competence protein
Q433_RS17915	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
Q433_RS17920	COG1307	EDD domain protein, DegV family
Q433_RS17925	COG2197	response regulator
Q433_RS17930	COG4585	Histidine kinase
Q433_RS17935	COG1739	Uncharacterized protein family UPF0029
Q433_RS17940	COG1316	TRANSCRIPTIONal
Q433_RS17945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Q433_RS17950	COG0438	transferase activity, transferring glycosyl groups
Q433_RS17955	COG1215	transferase activity, transferring glycosyl groups
Q433_RS17960	COG3206	protein involved in exopolysaccharide biosynthesis
Q433_RS17965	COG3307	-O-antigen
Q433_RS17970	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Q433_RS17975	COG0438	transferase activity, transferring glycosyl groups
Q433_RS17975	COG0297	glycogen (starch) synthase activity
Q433_RS17980	COG2244	polysaccharide biosynthetic process
Q433_RS17995	COG2247	cell wall binding repeat
Q433_RS17995	COG0860	N-Acetylmuramoyl-L-alanine amidase
Q433_RS18000	COG2247	cell wall binding repeat
Q433_RS18000	COG2385	sporulation resulting in formation of a cellular spore
Q433_RS18010	COG1316	TRANSCRIPTIONal
Q433_RS18015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Q433_RS18035	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Q433_RS18040	COG1134	teichoic acid transport
Q433_RS18045	COG1682	transport, permease protein
Q433_RS18060	COG1215	transferase activity, transferring glycosyl groups
Q433_RS18060	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Q433_RS18065	COG0463	Glycosyl transferase, family 2
Q433_RS18110	COG4193	domain, Protein
Q433_RS18115	COG1482	cell wall glycoprotein biosynthetic process
Q433_RS18125	COG0697	spore germination
Q433_RS18130	COG0814	amino acid
Q433_RS18140	COG2814	Major facilitator Superfamily
Q433_RS18145	COG1316	TRANSCRIPTIONal
Q433_RS18150	COG0561	phosphatase activity
Q433_RS18155	COG0791	NLP P60 protein
Q433_RS18165	COG2843	Capsule synthesis protein
Q433_RS18175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Q433_RS18180	COG1609	Transcriptional regulator
Q433_RS18185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q433_RS18190	COG1869	D-ribose catabolic process
Q433_RS18195	COG1129	ABC transporter
Q433_RS18200	COG1172	Belongs to the binding-protein-dependent transport system permease family
Q433_RS18205	COG1879	ABC-type sugar transport system periplasmic component
Q433_RS18210	COG3103	Sh3 type 3 domain protein
Q433_RS18220	COG2249	NAD(P)H dehydrogenase (quinone) activity
Q433_RS18225	COG3527	Alpha-acetolactate decarboxylase
Q433_RS18230	COG0028	Belongs to the TPP enzyme family
Q433_RS18235	COG0583	DNA-binding transcription factor activity
Q433_RS18240	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Q433_RS18255	COG5337	Spore coat protein CotH
Q433_RS18265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Q433_RS18275	COG0405	Gamma-glutamyltransferase
Q433_RS18280	COG1522	sequence-specific DNA binding
Q433_RS18285	COG2059	Chromate
Q433_RS18290	COG2059	Chromate
Q433_RS18300	COG0655	NAD(P)H dehydrogenase (quinone) activity
Q433_RS18305	COG0583	DNA-binding transcription factor activity
Q433_RS18335	COG5444	nuclease activity
Q433_RS18350	COG3878	Protein conserved in bacteria
Q433_RS18355	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Q433_RS18360	COG4464	protein tyrosine phosphatase activity
Q433_RS18365	COG0489	protein tyrosine kinase activity
Q433_RS18370	COG3944	biosynthesis protein
Q433_RS18380	COG4715	Zinc finger, swim domain protein
Q433_RS18385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q433_RS18390	COG0561	phosphatase activity
Q433_RS18395	COG1349	DNA-binding transcription factor activity
Q433_RS18400	COG0629	single-stranded DNA binding
Q433_RS18415	COG3764	Sortase (surface protein transpeptidase)
Q433_RS18420	COG0745	RESPONSE REGULATOR receiver
Q433_RS18420	COG2972	Histidine kinase
Q433_RS18425	COG1970	mechanosensitive ion channel activity
Q433_RS18430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Q433_RS18435	COG0457	Tetratricopeptide repeat
Q433_RS18440	COG4786	Flagellar basal body rod
Q433_RS18445	COG4786	Flagellar basal body rod
Q433_RS18450	COG1077	Cell shape determining protein MreB Mrl
Q433_RS18455	COG1609	Transcriptional regulator
Q433_RS18460	COG1846	Transcriptional regulator
Q433_RS18465	COG2814	Major facilitator Superfamily
Q433_RS18470	COG3420	alginic acid biosynthetic process
Q433_RS18475	COG1953	Uracil, thiamine, allantoin
Q433_RS18480	COG0477	Major facilitator Superfamily
Q433_RS18485	COG1335	isochorismatase
Q433_RS18495	COG0004	ammonium transporteR
Q433_RS18500	COG0347	Belongs to the P(II) protein family
Q433_RS18505	COG0671	phosphoesterase, PA-phosphatase related
Q433_RS18515	COG0739	heme binding
Q433_RS18520	COG1247	-acetyltransferase
Q433_RS18540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Q433_RS18545	COG0789	Transcriptional regulator
Q433_RS18555	COG2910	NAD(P)H-binding
Q433_RS18560	COG1959	2 iron, 2 sulfur cluster binding
Q433_RS18565	COG0804	urea catabolic process
Q433_RS18570	COG0832	Belongs to the urease beta subunit family
Q433_RS18575	COG0831	urea catabolic process
Q433_RS18590	COG3237	CsbD-like
Q433_RS18595	COG1994	Peptidase M50
Q433_RS18600	COG0457	Tetratricopeptide repeat
Q433_RS18605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Q433_RS18610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Q433_RS18620	COG2304	oxidoreductase activity
Q433_RS18630	COG2304	oxidoreductase activity
Q433_RS18635	COG2385	sporulation resulting in formation of a cellular spore
Q433_RS18640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Q433_RS18650	COG4836	Membrane
Q433_RS18660	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Q433_RS18665	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Q433_RS18670	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Q433_RS18675	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Q433_RS18680	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Q433_RS18685	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Q433_RS18700	COG0356	it plays a direct role in the translocation of protons across the membrane
Q433_RS18710	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Q433_RS18715	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Q433_RS18720	COG4475	Protein of unknown function (DUF436)
Q433_RS18725	COG0698	ribose 5-phosphate isomerase
Q433_RS18730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Q433_RS18735	COG1971	Probably functions as a manganese efflux pump
Q433_RS18740	COG0009	L-threonylcarbamoyladenylate synthase
Q433_RS18745	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Q433_RS18765	COG2890	protein-(glutamine-N5) methyltransferase activity
Q433_RS18770	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Q433_RS18775	COG0346	lactoylglutathione lyase activity
Q433_RS18780	COG0789	Transcriptional regulator
Q433_RS18785	COG0679	Auxin Efflux Carrier
Q433_RS18790	COG0281	malic enzyme
Q433_RS18795	COG1435	thymidine kinase activity
Q433_RS18805	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Q433_RS18815	COG1494	fructose-1,6-bisphosphatase
Q433_RS18820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Q433_RS18825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Q433_RS18830	COG0191	fructose-bisphosphate aldolase activity
Q433_RS18835	COG2204	response regulator
Q433_RS18840	COG4821	SIS domain
Q433_RS18845	COG0504	CTP synthase activity
Q433_RS18850	COG3343	RNA polymerase activity
Q433_RS18855	COG1960	acyl-CoA dehydrogenase activity
Q433_RS18860	COG0247	lactate metabolic process
Q433_RS18860	COG2181	nitrate reductase activity
Q433_RS18865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Q433_RS18870	COG4294	response to UV
Q433_RS18880	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Q433_RS18885	COG1132	(ABC) transporter
Q433_RS18890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Q433_RS18900	COG2181	nitrate reductase activity
Q433_RS18905	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Q433_RS18910	COG1140	nitrate reductase beta subunit
Q433_RS18915	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Q433_RS18920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Q433_RS18930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Q433_RS18935	COG2223	nitrite transmembrane transporter activity
Q433_RS18940	COG0018	arginyl-trna synthetase
Q433_RS18945	COG4506	Protein conserved in bacteria
Q433_RS18955	COG0535	radical SAM domain protein
Q433_RS18965	COG1131	(ABC) transporter
Q433_RS18970	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Q433_RS18975	COG0612	Peptidase, M16
Q433_RS18980	COG0612	Peptidase, M16
Q433_RS18990	COG3391	amine dehydrogenase activity
Q433_RS18995	COG3391	amine dehydrogenase activity
Q433_RS19005	COG0457	Tetratricopeptide repeat
Q433_RS19035	COG1131	(ABC) transporter
Q433_RS19045	COG0010	Belongs to the arginase family
Q433_RS19050	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Q433_RS19055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Q433_RS19065	COG1994	Peptidase M50
Q433_RS19070	COG1942	4-Oxalocrotonate Tautomerase
Q433_RS19075	COG1846	Transcriptional regulator
Q433_RS19080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Q433_RS19090	COG0477	Major facilitator Superfamily
Q433_RS19095	COG1959	2 iron, 2 sulfur cluster binding
Q433_RS19100	COG3465	dGTPase activity
Q433_RS19105	COG1078	dGTPase activity
Q433_RS19110	COG4844	belongs to the
Q433_RS19120	COG0697	spore germination
Q433_RS19125	COG0095	Lipoate-protein ligase
Q433_RS19130	COG0583	DNA-binding transcription factor activity
Q433_RS19135	COG0280	phosphate acetyltransferase
Q433_RS19145	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS19150	COG0436	Aminotransferase
Q433_RS19155	COG2814	Major facilitator Superfamily
Q433_RS19160	COG0151	Belongs to the GarS family
Q433_RS19165	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS19170	COG1917	Cupin 2, conserved barrel domain protein
Q433_RS19175	COG0077	Prephenate dehydratase
Q433_RS19180	COG2814	Major facilitator Superfamily
Q433_RS19185	COG0833	amino acid
Q433_RS19190	COG4187	Peptidase family M20/M25/M40
Q433_RS19195	COG1012	belongs to the aldehyde dehydrogenase family
Q433_RS19200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Q433_RS19210	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Q433_RS19215	COG1091	dTDP-4-dehydrorhamnose reductase activity
Q433_RS19220	COG1088	dTDP-glucose 4,6-dehydratase activity
Q433_RS19225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Q433_RS19230	COG3980	spore coat polysaccharide biosynthesis protein
Q433_RS19235	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
Q433_RS19240	COG2089	acid synthase
Q433_RS19245	COG0456	acetyltransferase
Q433_RS19250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Q433_RS19255	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Q433_RS19260	COG0463	Glycosyl transferase, family 2
Q433_RS19275	COG2363	Small membrane protein
Q433_RS19280	COG2233	PERMEase
Q433_RS19290	COG1012	belongs to the aldehyde dehydrogenase family
Q433_RS19295	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Q433_RS19300	COG1216	Glycosyl transferase, family 2
Q433_RS19305	COG0351	phosphomethylpyrimidine kinase
Q433_RS19315	COG1621	beta-fructofuranosidase activity
Q433_RS19320	COG1263	PTS System
Q433_RS19320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_RS19325	COG2116	formate transmembrane transporter activity
Q433_RS19330	COG3711	transcriptional antiterminator
Q433_RS19340	COG1404	Belongs to the peptidase S8 family
Q433_RS19345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Q433_RS19350	COG0778	Nitroreductase
Q433_RS19355	COG0772	Belongs to the SEDS family
Q433_RS19365	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Q433_RS19370	COG1845	cytochrome c oxidase, subunit III
Q433_RS19375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Q433_RS19380	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Q433_RS19385	COG2261	transglycosylase associated protein
Q433_RS19390	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
Q433_RS19395	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Q433_RS19400	COG2246	polysaccharide biosynthetic process
Q433_RS19405	COG1309	transcriptional regulator
Q433_RS19415	COG3162	membrane
Q433_RS19420	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q433_RS19425	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Q433_RS19430	COG2837	iron assimilation
Q433_RS19435	COG2822	iron ion transport
Q433_RS19440	COG0672	)-iron permease
Q433_RS19445	COG0352	thiamine-phosphate diphosphorylase activity
Q433_RS19450	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Q433_RS19455	COG0583	DNA-binding transcription factor activity
Q433_RS19460	COG1380	Effector of murein hydrolase LrgA
Q433_RS19465	COG1346	cytolysis
Q433_RS19470	COG2814	Major facilitator Superfamily
Q433_RS19475	COG4895	conserved protein (DUF2196)
Q433_RS19480	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Q433_RS19485	COG0346	lactoylglutathione lyase activity
Q433_RS19490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Q433_RS19495	COG1404	Belongs to the peptidase S8 family
Q433_RS19500	COG1263	PTS System
Q433_RS19500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_RS19505	COG3711	transcriptional antiterminator
Q433_RS19510	COG1442	glycosyl transferase family 8
Q433_RS19515	COG5522	Integral membrane protein (intg_mem_TP0381)
Q433_RS19520	COG1846	Transcriptional regulator
Q433_RS19525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Q433_RS19530	COG2234	aminopeptidase activity
Q433_RS19550	COG2357	RelA SpoT domain protein
Q433_RS19555	COG1575	Belongs to the MenA family. Type 1 subfamily
Q433_RS19570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_RS19575	COG1696	Membrane protein involved in D-alanine export
Q433_RS19580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q433_RS19585	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
Q433_RS19590	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
Q433_RS19595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Q433_RS19600	COG1486	melibiose metabolic process
Q433_RS19605	COG1447	Phosphotransferase system cellobiose-specific component IIA
Q433_RS19610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Q433_RS19615	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Q433_RS19620	COG3711	transcriptional antiterminator
Q433_RS19620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_RS19630	COG2094	Belongs to the DNA glycosylase MPG family
Q433_RS19635	COG0753	catalase activity
Q433_RS19645	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Q433_RS19650	COG1131	(ABC) transporter
Q433_RS19670	COG1595	DNA-templated transcription, initiation
Q433_RS19675	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Q433_RS19680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Q433_RS19685	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Q433_RS19690	COG4988	ABC transporter
Q433_RS19695	COG1294	oxidase, subunit
Q433_RS19700	COG1271	oxidase subunit
Q433_RS19705	COG3493	citrate carrier protein
Q433_RS19710	COG0501	Belongs to the peptidase M48B family
Q433_RS19720	COG0726	polysaccharide deacetylase
Q433_RS19725	COG3842	ATPase activity
Q433_RS19730	COG2508	Transcriptional regulator
Q433_RS19735	COG1012	belongs to the aldehyde dehydrogenase family
Q433_RS19740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_RS19750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Q433_RS19755	COG1881	PFAM PEBP family protein
Q433_RS19760	COG0583	DNA-binding transcription factor activity
Q433_RS19770	COG4585	Histidine kinase
Q433_RS19775	COG2197	response regulator
Q433_RS19780	COG2195	Cleaves the N-terminal amino acid of tripeptides
Q433_RS19795	COG4894	glucomannan catabolic process
Q433_RS19800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Q433_RS19805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Q433_RS19810	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS19815	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Q433_RS19820	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Q433_RS19825	COG2610	gluconate transmembrane transporter activity
Q433_RS19835	COG0500	methyltransferase
Q433_RS19840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Q433_RS19855	COG0693	protein deglycase activity
Q433_RS19855	COG0753	catalase activity
Q433_RS19860	COG2851	Citrate transporter
Q433_RS19865	COG2273	Hydrolase Family 16
Q433_RS19870	COG3711	transcriptional antiterminator
Q433_RS19880	COG2270	Major facilitator Superfamily
Q433_RS19885	COG0513	Belongs to the DEAD box helicase family
Q433_RS19890	COG3401	FG-GAP repeat protein
Q433_RS19890	COG2755	lipolytic protein G-D-S-L family
Q433_RS19940	COG3209	COG3209 Rhs family protein
Q433_RS19945	COG0697	spore germination
Q433_RS19975	COG0589	response to stress
Q433_RS19980	COG2723	6-phospho-beta-galactosidase activity
Q433_RS19985	COG2190	(PTS) system
Q433_RS19985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_RS19985	COG1263	PTS System
Q433_RS20000	COG5444	nuclease activity
Q433_RS20015	COG3507	Belongs to the glycosyl hydrolase 43 family
Q433_RS20030	COG2986	histidine ammonia-lyase
Q433_RS20035	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Q433_RS20040	COG1228	amidohydrolase
Q433_RS20045	COG0010	Belongs to the arginase family
Q433_RS20050	COG0833	amino acid
Q433_RS20055	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Q433_RS20060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Q433_RS20065	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Q433_RS20070	COG2390	Transcriptional regulator
Q433_RS20080	COG3192	ethanolamine utilization protein
Q433_RS20085	COG2079	MmgE PrpD family protein
Q433_RS20090	COG1473	amidohydrolase
Q433_RS20095	COG1126	abc transporter atp-binding protein
Q433_RS20100	COG0765	amino acid transport
Q433_RS20105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_RS20110	COG0456	acetyltransferase
Q433_RS20115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Q433_RS20125	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
Q433_RS20130	COG0561	phosphatase activity
Q433_RS20160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Q433_RS20165	COG5294	Protein conserved in bacteria
Q433_RS20170	COG0577	efflux transmembrane transporter activity
Q433_RS20175	COG1136	(ABC) transporter
Q433_RS20180	COG2205	protein histidine kinase activity
Q433_RS20185	COG0745	RESPONSE REGULATOR receiver
Q433_RS20190	COG0191	fructose-bisphosphate aldolase activity
Q433_RS20195	COG1082	Xylose isomerase domain protein TIM barrel
Q433_RS20200	COG1082	Xylose isomerase domain protein TIM barrel
Q433_RS20205	COG0673	inositol 2-dehydrogenase activity
Q433_RS20210	COG2814	Major facilitator Superfamily
Q433_RS20215	COG1082	Xylose isomerase domain protein TIM barrel
Q433_RS20220	COG3962	Belongs to the TPP enzyme family
Q433_RS20225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q433_RS20235	COG1012	belongs to the aldehyde dehydrogenase family
Q433_RS20240	COG1349	DNA-binding transcription factor activity
Q433_RS20245	COG0667	Aldo Keto reductase
Q433_RS20260	COG2814	Major facilitator Superfamily
Q433_RS20275	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS20280	COG1309	transcriptional regulator
Q433_RS20285	COG1012	belongs to the aldehyde dehydrogenase family
Q433_RS20295	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Q433_RS20305	COG1714	RDD family
Q433_RS20310	COG2311	Membrane
Q433_RS20315	COG1917	Cupin 2, conserved barrel domain protein
Q433_RS20320	COG1309	transcriptional regulator
Q433_RS20325	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_RS20330	COG1846	Transcriptional regulator
Q433_RS20335	COG1380	Effector of murein hydrolase LrgA
Q433_RS20340	COG1346	cytolysis
Q433_RS20345	COG5039	Polysaccharide pyruvyl transferase
Q433_RS20350	COG1929	Belongs to the glycerate kinase type-1 family
Q433_RS20355	COG1802	Transcriptional regulator
Q433_RS20360	COG1070	Carbohydrate kinase
Q433_RS20365	COG2610	gluconate transmembrane transporter activity
Q433_RS20370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Q433_RS20375	COG0450	alkyl hydroperoxide reductase
Q433_RS20380	COG3634	alkyl hydroperoxide reductase activity
Q433_RS20390	COG2723	6-phospho-beta-galactosidase activity
Q433_RS20400	COG2188	Transcriptional regulator
Q433_RS20410	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
Q433_RS20440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Q433_RS20450	COG1063	alcohol dehydrogenase
Q433_RS20470	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
Q433_RS20475	COG0456	acetyltransferase
Q433_RS20480	COG0457	Tetratricopeptide repeat
Q433_RS20490	COG0010	Belongs to the arginase family
Q433_RS20495	COG0833	amino acid
Q433_RS20500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Q433_RS20505	COG3829	transcription factor binding
Q433_RS20510	COG5002	protein histidine kinase activity
Q433_RS20535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q433_RS20540	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Q433_RS20545	COG4853	Protein conserved in bacteria
Q433_RS20550	COG4863	YycH protein
Q433_RS20555	COG5002	protein histidine kinase activity
Q433_RS20560	COG0745	RESPONSE REGULATOR receiver
Q433_RS20590	COG0346	lactoylglutathione lyase activity
Q433_RS20595	COG0305	Participates in initiation and elongation during chromosome replication
Q433_RS20615	COG3093	addiction module antidote protein HigA
Q433_RS20620	COG2807	transmembrane transport
Q433_RS20625	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Q433_RS20630	COG0359	binds to the 23S rRNA
Q433_RS20635	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Q433_RS20640	COG4241	membrane
Q433_RS20650	COG5577	PFAM Coat F domain
Q433_RS20655	COG1733	regulation of RNA biosynthetic process
Q433_RS20660	COG1227	inorganic diphosphatase activity
Q433_RS20675	COG2271	Major facilitator Superfamily
Q433_RS20680	COG0789	Transcriptional regulator
Q433_RS20680	COG4978	Transcriptional regulator
Q433_RS20690	COG4319	ketosteroid isomerase
Q433_RS20695	COG1357	PFAM Pentapeptide repeats (8 copies)
Q433_RS20700	COG2814	Major facilitator Superfamily
Q433_RS20705	COG0583	DNA-binding transcription factor activity
Q433_RS20710	COG2153	protein acetylation
Q433_RS20720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_RS20725	COG1846	Transcriptional regulator
Q433_RS20730	COG2153	protein acetylation
Q433_RS20735	COG2364	Membrane
Q433_RS20740	COG0456	acetyltransferase
Q433_RS20745	COG2315	Protein conserved in bacteria
Q433_RS20750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Q433_RS20755	COG2814	Major facilitator Superfamily
Q433_RS20760	COG1331	Highly conserved protein containing a thioredoxin domain
Q433_RS20765	COG1266	CAAX protease self-immunity
Q433_RS20770	COG0477	Major facilitator Superfamily
Q433_RS20770	COG2814	Major facilitator Superfamily
Q433_RS20775	COG0110	maltose O-acetyltransferase activity
Q433_RS20780	COG0346	lactoylglutathione lyase activity
Q433_RS20785	COG1609	Transcriptional regulator
Q433_RS20790	COG0708	Exodeoxyribonuclease III
Q433_RS20795	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Q433_RS20800	COG0629	single-stranded DNA binding
Q433_RS20805	COG0360	Binds together with S18 to 16S ribosomal RNA
Q433_RS20810	COG0012	GTP binding
Q433_RS20815	COG0243	molybdopterin cofactor binding
Q433_RS20820	COG4481	Protein conserved in bacteria
Q433_RS20825	COG3949	Membrane
Q433_RS20835	COG1475	DNA binding
Q433_RS20840	COG1192	Involved in chromosome partitioning
Q433_RS20850	COG1475	DNA binding
Q433_RS20855	COG0357	Ribosomal RNA small subunit methyltransferase G
Q433_RS20860	COG0445	tRNA wobble uridine modification
Q433_RS20865	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Q433_RS20870	COG1847	R3H domain protein
Q433_RS20875	COG0706	membrane insertase activity
Q433_RS20880	COG0594	ribonuclease P activity
Q433_RS21035	COG5577	PFAM Coat F domain
Q433_RS21310	COG1971	Probably functions as a manganese efflux pump
Q433_RS21395	COG0789	Transcriptional regulator
Q433_RS21400	COG2190	(PTS) system
Q433_RS21405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_RS21405	COG2190	(PTS) system
Q433_RS21405	COG1263	PTS System
Q433_RS21435	COG2312	Erythromycin esterase
Q433_RS21460	COG1073	alpha beta
Q433_RS21580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Q433_RS21585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family