locus-tag	class	description
K8Z39_RS00015	COG3331	DNA recombination
K8Z39_RS00160	COG0582	viral genome integration into host DNA
K8Z39_RS00180	COG1266	CAAX protease self-immunity
K8Z39_RS00195	COG0488	(ABC) transporter
K8Z39_RS00205	COG0456	acetyltransferase
K8Z39_RS00210	COG1214	PFAM Peptidase M22, glycoprotease
K8Z39_RS00215	COG0802	atpase or kinase
K8Z39_RS00315	COG2183	response to ionizing radiation
K8Z39_RS00320	COG2337	Toxic component of a toxin-antitoxin (TA) module
K8Z39_RS00325	COG0864	Transcriptional regulator
K8Z39_RS00330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z39_RS00335	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K8Z39_RS00345	COG0705	Rhomboid family
K8Z39_RS00350	COG4294	response to UV
K8Z39_RS00360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K8Z39_RS00370	COG2814	Major facilitator Superfamily
K8Z39_RS00375	COG0531	amino acid
K8Z39_RS00385	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z39_RS00390	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K8Z39_RS00410	COG0561	phosphatase activity
K8Z39_RS00420	COG4608	Belongs to the ABC transporter superfamily
K8Z39_RS00425	COG0444	Belongs to the ABC transporter superfamily
K8Z39_RS00430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z39_RS00435	COG0601	transmembrane transport
K8Z39_RS00440	COG0747	negative chemotaxis
K8Z39_RS00450	COG0488	(ABC) transporter
K8Z39_RS00475	COG5298	Protein conserved in bacteria
K8Z39_RS00495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_RS00505	COG1609	Transcriptional regulator
K8Z39_RS00515	COG0204	Acyl-transferase
K8Z39_RS00530	COG0697	spore germination
K8Z39_RS00545	COG1910	domain protein
K8Z39_RS00550	COG0725	ABC transporter, periplasmic molybdate-binding protein
K8Z39_RS00555	COG4149	molybdate abc transporter
K8Z39_RS00570	COG0656	L-ascorbic acid biosynthetic process
K8Z39_RS00575	COG4166	transmembrane transport
K8Z39_RS00580	COG4166	transmembrane transport
K8Z39_RS00595	COG2207	Transcriptional regulator
K8Z39_RS00615	COG2814	Major facilitator Superfamily
K8Z39_RS00625	COG2271	Major facilitator Superfamily
K8Z39_RS00630	COG0277	FAD linked oxidase domain protein
K8Z39_RS00640	COG0604	alcohol dehydrogenase
K8Z39_RS00645	COG1464	Belongs to the NlpA lipoprotein family
K8Z39_RS00650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K8Z39_RS00655	COG2011	ABC-type metal ion transport system permease component
K8Z39_RS00660	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS00695	COG4856	YbbR-like protein
K8Z39_RS00700	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
K8Z39_RS00780	COG0726	polysaccharide deacetylase
K8Z39_RS00785	COG2194	sulfuric ester hydrolase activity
K8Z39_RS00795	COG0489	protein tyrosine kinase activity
K8Z39_RS00800	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K8Z39_RS00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K8Z39_RS00870	COG0024	Methionine aminopeptidase
K8Z39_RS00880	COG0201	protein transport
K8Z39_RS00940	COG0255	Belongs to the universal ribosomal protein uL29 family
K8Z39_RS01005	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K8Z39_RS01010	COG1358	cellular component organization or biogenesis
K8Z39_RS01025	COG2813	Specifically methylates the guanine in position
K8Z39_RS01045	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K8Z39_RS01050	COG0250	Participates in transcription elongation, termination and antitermination
K8Z39_RS01055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z39_RS01070	COG3688	RNA-binding protein containing a PIN domain
K8Z39_RS01075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z39_RS01090	COG1045	serine acetyltransferase
K8Z39_RS01110	COG4956	integral membrane protein (PIN domain superfamily)
K8Z39_RS01120	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K8Z39_RS01125	COG0542	response to heat
K8Z39_RS01135	COG3880	PFAM UvrB UvrC protein
K8Z39_RS01225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z39_RS01230	COG1396	sequence-specific DNA binding
K8Z39_RS01235	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K8Z39_RS01240	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K8Z39_RS01245	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K8Z39_RS01250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z39_RS01255	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z39_RS01260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K8Z39_RS01265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z39_RS01280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K8Z39_RS01285	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z39_RS01295	COG2208	phosphoserine phosphatase activity
K8Z39_RS01310	COG1098	S1 RNA binding domain
K8Z39_RS01330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K8Z39_RS01335	COG3956	TIGRFAM MazG family protein
K8Z39_RS01340	COG2244	polysaccharide biosynthetic process
K8Z39_RS01345	COG2002	toxin-antitoxin pair type II binding
K8Z39_RS01350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K8Z39_RS01380	COG0251	oxidation-reduction process
K8Z39_RS01385	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K8Z39_RS01400	COG4466	Protein conserved in bacteria
K8Z39_RS01420	COG0084	hydrolase, TatD family'
K8Z39_RS01430	COG2002	toxin-antitoxin pair type II binding
K8Z39_RS01435	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K8Z39_RS01445	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K8Z39_RS01455	COG1774	PSP1 C-terminal conserved region
K8Z39_RS01460	COG0470	DNA polymerase III
K8Z39_RS01470	COG1982	Orn Lys Arg decarboxylase major
K8Z39_RS01525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K8Z39_RS01535	COG0590	tRNA wobble adenosine to inosine editing
K8Z39_RS01540	COG1335	isochorismatase
K8Z39_RS01545	COG1428	Deoxynucleoside kinase
K8Z39_RS01550	COG1428	Deoxynucleoside kinase
K8Z39_RS01580	COG1686	Belongs to the peptidase S11 family
K8Z39_RS01585	COG0516	GMP reductase activity
K8Z39_RS01585	COG0517	IMP dehydrogenase activity
K8Z39_RS01620	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z39_RS01625	COG0187	DNA topoisomerase II activity
K8Z39_RS01635	COG2501	S4 domain
K8Z39_RS01640	COG0592	DNA-directed DNA polymerase activity
K8Z39_RS01650	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K8Z39_RS01665	COG1847	R3H domain protein
K8Z39_RS01690	COG1192	Involved in chromosome partitioning
K8Z39_RS01695	COG1475	DNA binding
K8Z39_RS01705	COG0668	transmembrane transport
K8Z39_RS01710	COG4481	Protein conserved in bacteria
K8Z39_RS01715	COG0012	GTP binding
K8Z39_RS01735	COG4241	membrane
K8Z39_RS01740	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
K8Z39_RS01750	COG0305	Participates in initiation and elongation during chromosome replication
K8Z39_RS01780	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS01785	COG5002	protein histidine kinase activity
K8Z39_RS01795	COG4853	Protein conserved in bacteria
K8Z39_RS01800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K8Z39_RS01805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z39_RS01820	COG5002	protein histidine kinase activity
K8Z39_RS01855	COG1272	protein, Hemolysin III
K8Z39_RS01860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z39_RS01895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z39_RS01900	COG2814	Major facilitator Superfamily
K8Z39_RS01905	COG3275	phosphorelay sensor kinase activity
K8Z39_RS01925	COG0628	permease
K8Z39_RS01935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z39_RS01940	COG1309	transcriptional regulator
K8Z39_RS01945	COG0488	(ABC) transporter
K8Z39_RS01950	COG0463	Glycosyl transferase, family 2
K8Z39_RS01955	COG4485	Bacterial membrane protein, YfhO
K8Z39_RS01965	COG1216	Glycosyl transferase, family 2
K8Z39_RS01980	COG1216	Glycosyl transferase, family 2
K8Z39_RS01985	COG1607	acyl-coa hydrolase
K8Z39_RS01995	COG0840	transmembrane signaling receptor activity
K8Z39_RS02010	COG0438	transferase activity, transferring glycosyl groups
K8Z39_RS02020	COG0477	Major facilitator Superfamily
K8Z39_RS02025	COG3279	Response regulator of the LytR AlgR family
K8Z39_RS02030	COG1966	Carbon starvation protein
K8Z39_RS02035	COG2879	small protein
K8Z39_RS02040	COG3706	GGDEF domain
K8Z39_RS02045	COG0351	phosphomethylpyrimidine kinase
K8Z39_RS02050	COG4585	Histidine kinase
K8Z39_RS02050	COG2203	Gaf domain
K8Z39_RS02055	COG2197	response regulator
K8Z39_RS02065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z39_RS02070	COG1011	Hydrolase
K8Z39_RS02080	COG2873	o-acetylhomoserine
K8Z39_RS02090	COG0460	homoserine dehydrogenase
K8Z39_RS02100	COG1609	Transcriptional regulator
K8Z39_RS02105	COG2755	lipolytic protein G-D-S-L family
K8Z39_RS02110	COG1131	(ABC) transporter
K8Z39_RS02125	COG2814	Major facilitator Superfamily
K8Z39_RS02130	COG0561	phosphatase activity
K8Z39_RS02135	COG2233	PERMEase
K8Z39_RS02140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z39_RS02150	COG2363	Small membrane protein
K8Z39_RS02160	COG3773	Cell wall hydrolase
K8Z39_RS02175	COG0280	phosphate acetyltransferase
K8Z39_RS02195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_RS02200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_RS02205	COG1120	ATPase activity
K8Z39_RS02210	COG2801	Transposase and inactivated derivatives
K8Z39_RS02220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_RS02225	COG1078	dGTPase activity
K8Z39_RS02235	COG1994	Peptidase M50
K8Z39_RS02245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z39_RS02250	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z39_RS02255	COG0789	Transcriptional regulator
K8Z39_RS02260	COG2814	Major facilitator Superfamily
K8Z39_RS02290	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z39_RS02295	COG4506	Protein conserved in bacteria
K8Z39_RS02305	COG1595	DNA-templated transcription, initiation
K8Z39_RS02325	COG2234	aminopeptidase activity
K8Z39_RS02345	COG0024	Methionine aminopeptidase
K8Z39_RS02350	COG1131	(ABC) transporter
K8Z39_RS02355	COG0842	Transport permease protein
K8Z39_RS02360	COG4585	Histidine kinase
K8Z39_RS02365	COG2197	response regulator
K8Z39_RS02370	COG3227	Zinc metalloprotease (Elastase)
K8Z39_RS02385	COG3300	MHYT domain
K8Z39_RS02385	COG5001	Diguanylate cyclase
K8Z39_RS02395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z39_RS02400	COG0247	lactate metabolic process
K8Z39_RS02400	COG2181	nitrate reductase activity
K8Z39_RS02405	COG0183	Belongs to the thiolase family
K8Z39_RS02410	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z39_RS02415	COG1960	acyl-CoA dehydrogenase activity
K8Z39_RS02420	COG1960	acyl-CoA dehydrogenase activity
K8Z39_RS02430	COG3343	RNA polymerase activity
K8Z39_RS02440	COG4821	SIS domain
K8Z39_RS02460	COG1494	fructose-1,6-bisphosphatase
K8Z39_RS02465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K8Z39_RS02500	COG0009	L-threonylcarbamoyladenylate synthase
K8Z39_RS02515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z39_RS02520	COG2259	Doxx family
K8Z39_RS02535	COG0698	ribose 5-phosphate isomerase
K8Z39_RS02570	COG0356	it plays a direct role in the translocation of protons across the membrane
K8Z39_RS02620	COG5001	Diguanylate cyclase
K8Z39_RS02620	COG3300	MHYT domain
K8Z39_RS02635	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z39_RS02655	COG0839	Belongs to the complex I subunit 6 family
K8Z39_RS02665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z39_RS02670	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z39_RS02675	COG1007	ATP synthesis coupled electron transport
K8Z39_RS02680	COG4836	Membrane
K8Z39_RS02695	COG2385	sporulation resulting in formation of a cellular spore
K8Z39_RS02700	COG3279	Response regulator of the LytR AlgR family
K8Z39_RS02715	COG0739	heme binding
K8Z39_RS02725	COG1609	Transcriptional regulator
K8Z39_RS02740	COG0489	protein tyrosine kinase activity
K8Z39_RS02745	COG3944	biosynthesis protein
K8Z39_RS02750	COG0489	protein tyrosine kinase activity
K8Z39_RS02755	COG4464	protein tyrosine phosphatase activity
K8Z39_RS02760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z39_RS02775	COG1216	Glycosyl transferase, family 2
K8Z39_RS02785	COG0438	transferase activity, transferring glycosyl groups
K8Z39_RS02790	COG0463	Glycosyl transferase, family 2
K8Z39_RS02795	COG1215	transferase activity, transferring glycosyl groups
K8Z39_RS02800	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z39_RS02805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z39_RS02810	COG1316	TRANSCRIPTIONal
K8Z39_RS02820	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS02825	COG5002	protein histidine kinase activity
K8Z39_RS02850	COG1136	(ABC) transporter
K8Z39_RS02855	COG0577	efflux transmembrane transporter activity
K8Z39_RS02895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z39_RS02900	COG4715	Zinc finger, swim domain protein
K8Z39_RS02925	COG1388	LysM domain
K8Z39_RS02925	COG3584	3D domain protein
K8Z39_RS02930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z39_RS02945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_RS02950	COG1388	LysM domain
K8Z39_RS02950	COG0791	NLP P60 protein
K8Z39_RS02965	COG1368	sulfuric ester hydrolase activity
K8Z39_RS02975	COG2389	metal-binding protein
K8Z39_RS02990	COG1620	l-lactate permease
K8Z39_RS03000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z39_RS03005	COG1294	oxidase, subunit
K8Z39_RS03010	COG1271	oxidase subunit
K8Z39_RS03020	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
K8Z39_RS03025	COG0583	DNA-binding transcription factor activity
K8Z39_RS03030	COG1511	domain protein
K8Z39_RS03045	COG1301	dicarboxylic acid transport
K8Z39_RS03050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z39_RS03060	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z39_RS03070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z39_RS03075	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z39_RS03080	COG1486	melibiose metabolic process
K8Z39_RS03100	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K8Z39_RS03100	COG3933	PFAM sigma-54 factor interaction domain-containing protein
K8Z39_RS03110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K8Z39_RS03115	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z39_RS03120	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K8Z39_RS03125	COG1316	TRANSCRIPTIONal
K8Z39_RS03130	COG1739	Uncharacterized protein family UPF0029
K8Z39_RS03135	COG1307	EDD domain protein, DegV family
K8Z39_RS03140	COG1733	regulation of RNA biosynthetic process
K8Z39_RS03145	COG0791	NLP P60 protein
K8Z39_RS03145	COG1388	LysM domain
K8Z39_RS03150	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
K8Z39_RS03155	COG1040	competence protein
K8Z39_RS03160	COG1278	Cold shock
K8Z39_RS03165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K8Z39_RS03195	COG1131	(ABC) transporter
K8Z39_RS03220	COG2884	Cell division ATP-binding protein ftsE
K8Z39_RS03225	COG2177	Part of the ABC transporter FtsEX involved in
K8Z39_RS03230	COG0793	Belongs to the peptidase S41A family
K8Z39_RS03230	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_RS03235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z39_RS03260	COG0488	(ABC) transporter
K8Z39_RS03265	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z39_RS03275	COG0583	DNA-binding transcription factor activity
K8Z39_RS03295	COG0789	Transcriptional regulator
K8Z39_RS03310	COG0556	nucleotide-excision repair
K8Z39_RS03315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K8Z39_RS03325	COG1950	PFAM Membrane protein of
K8Z39_RS03345	COG0110	maltose O-acetyltransferase activity
K8Z39_RS03350	COG0457	Tetratricopeptide repeat
K8Z39_RS03355	COG0492	ferredoxin-NADP+ reductase activity
K8Z39_RS03365	COG1051	belongs to the nudix hydrolase family
K8Z39_RS03375	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K8Z39_RS03385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z39_RS03395	COG2323	membrane
K8Z39_RS03410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z39_RS03435	COG0582	viral genome integration into host DNA
K8Z39_RS03465	COG3646	Phage regulatory protein
K8Z39_RS03555	COG3331	DNA recombination
K8Z39_RS03690	COG4824	toxin secretion phage lysis holin
K8Z39_RS03695	COG1388	LysM domain
K8Z39_RS03695	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS03695	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_RS03720	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K8Z39_RS03735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z39_RS03770	COG1346	cytolysis
K8Z39_RS03775	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z39_RS03780	COG1647	Serine aminopeptidase, S33
K8Z39_RS03785	COG0557	exoribonuclease II activity
K8Z39_RS03830	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS03875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS03880	COG0488	(ABC) transporter
K8Z39_RS03935	COG1252	NADH dehydrogenase
K8Z39_RS03945	COG1733	regulation of RNA biosynthetic process
K8Z39_RS03950	COG2814	Major facilitator Superfamily
K8Z39_RS03955	COG0656	L-ascorbic acid biosynthetic process
K8Z39_RS03970	COG2910	NAD(P)H-binding
K8Z39_RS03975	COG1115	amino acid carrier protein
K8Z39_RS03980	COG1115	amino acid carrier protein
K8Z39_RS03985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_RS03990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_RS03995	COG2311	Membrane
K8Z39_RS04000	COG1528	Iron-storage protein
K8Z39_RS04010	COG1611	Belongs to the LOG family
K8Z39_RS04025	COG0783	Belongs to the Dps family
K8Z39_RS04030	COG1115	amino acid carrier protein
K8Z39_RS04035	COG0490	domain, Protein
K8Z39_RS04040	COG0475	glutathione-regulated potassium exporter activity
K8Z39_RS04045	COG0586	Pfam SNARE associated Golgi protein
K8Z39_RS04065	COG3227	Zinc metalloprotease (Elastase)
K8Z39_RS04090	COG4974	Belongs to the 'phage' integrase family
K8Z39_RS04110	COG2151	metal-sulfur cluster biosynthetic enzyme
K8Z39_RS04115	COG0840	transmembrane signaling receptor activity
K8Z39_RS04145	COG5002	protein histidine kinase activity
K8Z39_RS04150	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS04155	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z39_RS04165	COG0586	Pfam SNARE associated Golgi protein
K8Z39_RS04200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_RS04220	COG0531	amino acid
K8Z39_RS04225	COG2814	Major facilitator Superfamily
K8Z39_RS04240	COG0840	transmembrane signaling receptor activity
K8Z39_RS04245	COG0011	TIGRFAM Protein of
K8Z39_RS04260	COG1686	Belongs to the peptidase S11 family
K8Z39_RS04270	COG1024	Enoyl-CoA hydratase
K8Z39_RS04270	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z39_RS04275	COG0183	Belongs to the thiolase family
K8Z39_RS04280	COG1960	acyl-CoA dehydrogenase activity
K8Z39_RS04285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_RS04290	COG1309	transcriptional regulator
K8Z39_RS04305	COG0039	L-malate dehydrogenase activity
K8Z39_RS04325	COG1393	Belongs to the ArsC family
K8Z39_RS04335	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K8Z39_RS04340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z39_RS04355	COG2011	ABC-type metal ion transport system permease component
K8Z39_RS04360	COG1464	Belongs to the NlpA lipoprotein family
K8Z39_RS04365	COG1464	Belongs to the NlpA lipoprotein family
K8Z39_RS04370	COG0396	ATPase activity
K8Z39_RS04375	COG0719	Fe-S assembly protein
K8Z39_RS04380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K8Z39_RS04385	COG0822	iron-sulfur transferase activity
K8Z39_RS04390	COG0719	Fe-S assembly protein
K8Z39_RS04395	COG0582	viral genome integration into host DNA
K8Z39_RS04400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K8Z39_RS04480	COG1396	sequence-specific DNA binding
K8Z39_RS04620	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS04645	COG2801	Transposase and inactivated derivatives
K8Z39_RS04650	COG0737	Belongs to the 5'-nucleotidase family
K8Z39_RS04655	COG3377	Domain of unknown function (DUF1805)
K8Z39_RS04665	COG0739	heme binding
K8Z39_RS04690	COG4377	Putative membrane peptidase family (DUF2324)
K8Z39_RS04695	COG0789	Transcriptional regulator
K8Z39_RS04705	COG4470	Protein conserved in bacteria
K8Z39_RS04725	COG1494	fructose-1,6-bisphosphatase
K8Z39_RS04730	COG2445	Protein of unknown function DUF86
K8Z39_RS04740	COG0647	UMP catabolic process
K8Z39_RS04745	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z39_RS04755	COG1358	cellular component organization or biogenesis
K8Z39_RS04775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K8Z39_RS04780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z39_RS04790	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K8Z39_RS04795	COG4837	Protein of unknown function (DUF1462)
K8Z39_RS04840	COG2824	Alkylphosphonate utilization operon protein PhnA
K8Z39_RS04845	COG0390	transport system, permease component
K8Z39_RS04860	COG1252	NADH dehydrogenase
K8Z39_RS04875	COG0316	Belongs to the HesB IscA family
K8Z39_RS04915	COG3620	sequence-specific DNA binding
K8Z39_RS04925	COG3645	SOS response
K8Z39_RS04925	COG3646	Phage regulatory protein
K8Z39_RS04950	COG1191	sigma factor activity
K8Z39_RS05085	COG4824	toxin secretion phage lysis holin
K8Z39_RS05090	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_RS05090	COG1388	LysM domain
K8Z39_RS05090	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS05145	COG1683	Conserved Protein
K8Z39_RS05175	COG1252	NADH dehydrogenase
K8Z39_RS05190	COG3584	3D domain protein
K8Z39_RS05205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K8Z39_RS05210	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z39_RS05215	COG1268	BioY protein
K8Z39_RS05225	COG2050	protein possibly involved in aromatic compounds catabolism
K8Z39_RS05250	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z39_RS05255	COG5018	Exonuclease
K8Z39_RS05275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K8Z39_RS05285	COG2267	carboxylic ester hydrolase activity
K8Z39_RS05290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z39_RS05300	COG0436	Aminotransferase
K8Z39_RS05305	COG1098	S1 RNA binding domain
K8Z39_RS05310	COG2155	Conserved Protein
K8Z39_RS05325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z39_RS05330	COG1285	pathogenesis
K8Z39_RS05365	COG0544	peptidyl-prolyl cis-trans isomerase activity
K8Z39_RS05480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K8Z39_RS05490	COG0058	SHG alpha-glucan phosphorylase activity
K8Z39_RS05515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K8Z39_RS05520	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z39_RS05525	COG1169	isochorismate synthase
K8Z39_RS05535	COG0596	Alpha beta hydrolase
K8Z39_RS05540	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K8Z39_RS05560	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z39_RS05580	COG3964	amidohydrolase
K8Z39_RS05600	COG2188	Transcriptional regulator
K8Z39_RS05630	COG0577	efflux transmembrane transporter activity
K8Z39_RS05635	COG1136	(ABC) transporter
K8Z39_RS05640	COG0577	efflux transmembrane transporter activity
K8Z39_RS05645	COG0577	efflux transmembrane transporter activity
K8Z39_RS05650	COG2205	protein histidine kinase activity
K8Z39_RS05655	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS05660	COG0640	Transcriptional regulator
K8Z39_RS05665	COG5658	integral membrane protein
K8Z39_RS05675	COG3708	Transcriptional regulator
K8Z39_RS05675	COG2207	Transcriptional regulator
K8Z39_RS05680	COG1136	(ABC) transporter
K8Z39_RS05685	COG0577	efflux transmembrane transporter activity
K8Z39_RS05695	COG0586	Pfam SNARE associated Golgi protein
K8Z39_RS05725	COG1597	lipid kinase activity
K8Z39_RS05730	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z39_RS05755	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS05760	COG5002	protein histidine kinase activity
K8Z39_RS05800	COG1842	Phage shock protein A
K8Z39_RS05820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_RS05835	COG2801	Transposase and inactivated derivatives
K8Z39_RS05845	COG1294	oxidase, subunit
K8Z39_RS05850	COG1271	oxidase subunit
K8Z39_RS05865	COG1854	S-ribosylhomocysteine lyase activity
K8Z39_RS05895	COG0494	nUDIX hydrolase
K8Z39_RS05920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z39_RS05925	COG1116	anion transmembrane transporter activity
K8Z39_RS05930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z39_RS05955	COG1368	sulfuric ester hydrolase activity
K8Z39_RS05960	COG2267	carboxylic ester hydrolase activity
K8Z39_RS05965	COG3852	Histidine kinase
K8Z39_RS05970	COG5002	protein histidine kinase activity
K8Z39_RS05985	COG1349	DNA-binding transcription factor activity
K8Z39_RS06030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS06055	COG0438	transferase activity, transferring glycosyl groups
K8Z39_RS06060	COG0671	phosphoesterase, PA-phosphatase related
K8Z39_RS06065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K8Z39_RS06070	COG2267	carboxylic ester hydrolase activity
K8Z39_RS06090	COG1794	racemase activity, acting on amino acids and derivatives
K8Z39_RS06095	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
K8Z39_RS06100	COG1242	4 iron, 4 sulfur cluster binding
K8Z39_RS06120	COG1136	(ABC) transporter
K8Z39_RS06130	COG0582	viral genome integration into host DNA
K8Z39_RS06135	COG0490	domain, Protein
K8Z39_RS06140	COG0475	glutathione-regulated potassium exporter activity
K8Z39_RS06145	COG2814	Major facilitator Superfamily
K8Z39_RS06190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K8Z39_RS06200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z39_RS06220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z39_RS06225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z39_RS06235	COG0303	'Molybdopterin
K8Z39_RS06240	COG1763	Mo-molybdopterin cofactor biosynthetic process
K8Z39_RS06245	COG0314	molybdopterin synthase activity
K8Z39_RS06270	COG1329	Transcriptional regulator
K8Z39_RS06290	COG3832	glyoxalase III activity
K8Z39_RS06300	COG2814	Major facilitator Superfamily
K8Z39_RS06305	COG2081	HI0933 family
K8Z39_RS06310	COG2244	polysaccharide biosynthetic process
K8Z39_RS06315	COG1187	pseudouridine synthase activity
K8Z39_RS06320	COG1349	DNA-binding transcription factor activity
K8Z39_RS06325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z39_RS06335	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z39_RS06340	COG0510	thiamine kinase activity
K8Z39_RS06355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_RS06365	COG1363	Peptidase, m42
K8Z39_RS06370	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
K8Z39_RS06375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z39_RS06385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z39_RS06400	COG1674	ftsk spoiiie
K8Z39_RS06415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS06430	COG2309	aminopeptidase activity
K8Z39_RS06440	COG3118	belongs to the thioredoxin family
K8Z39_RS06445	COG4851	CamS sex pheromone cAM373 precursor
K8Z39_RS06450	COG1605	Chorismate mutase
K8Z39_RS06450	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z39_RS06455	COG1609	Transcriptional regulator
K8Z39_RS06490	COG3279	Response regulator of the LytR AlgR family
K8Z39_RS06510	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS06510	COG2972	Histidine kinase
K8Z39_RS06515	COG0666	response to abiotic stimulus
K8Z39_RS06525	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS06540	COG0123	including yeast histone deacetylase and acetoin utilization protein
K8Z39_RS06545	COG0517	IMP dehydrogenase activity
K8Z39_RS06550	COG0454	-acetyltransferase
K8Z39_RS06555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z39_RS06560	COG0110	maltose O-acetyltransferase activity
K8Z39_RS06570	COG1595	DNA-templated transcription, initiation
K8Z39_RS06625	COG0626	cystathionine gamma-synthase activity
K8Z39_RS06630	COG1956	GAF domain-containing protein
K8Z39_RS06635	COG1309	transcriptional regulator
K8Z39_RS06640	COG0697	spore germination
K8Z39_RS06645	COG0583	DNA-binding transcription factor activity
K8Z39_RS06655	COG1104	cysteine desulfurase activity
K8Z39_RS06670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z39_RS06680	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K8Z39_RS06695	COG3874	Sporulation protein YtfJ
K8Z39_RS06700	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K8Z39_RS06705	COG0827	DNA restriction-modification system
K8Z39_RS06730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_RS06770	COG0589	response to stress
K8Z39_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS06790	COG0662	Cupin 2, conserved barrel domain protein
K8Z39_RS06830	COG0006	proline dipeptidase activity
K8Z39_RS06845	COG4109	DRTGG domain
K8Z39_RS06860	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K8Z39_RS06875	COG0587	DNA-directed DNA polymerase activity
K8Z39_RS06880	COG0281	malic enzyme
K8Z39_RS06885	COG1725	Transcriptional regulator
K8Z39_RS06910	COG3030	protein affecting phage T7 exclusion by the F plasmid
K8Z39_RS06915	COG0628	permease
K8Z39_RS06925	COG0372	Belongs to the citrate synthase family
K8Z39_RS06930	COG0538	isocitrate dehydrogenase activity
K8Z39_RS06950	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS06955	COG5002	protein histidine kinase activity
K8Z39_RS06960	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z39_RS06960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z39_RS06970	COG1971	Probably functions as a manganese efflux pump
K8Z39_RS06980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z39_RS06985	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K8Z39_RS06995	COG3611	Membrane attachment protein
K8Z39_RS07000	COG1484	DNA-dependent DNA replication
K8Z39_RS07015	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z39_RS07040	COG1363	Peptidase, m42
K8Z39_RS07045	COG1309	transcriptional regulator
K8Z39_RS07050	COG1566	PFAM secretion protein HlyD family protein
K8Z39_RS07055	COG2814	Major facilitator Superfamily
K8Z39_RS07075	COG1418	mRNA catabolic process
K8Z39_RS07085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z39_RS07130	COG1286	toxin biosynthetic process
K8Z39_RS07135	COG1796	DNA polymerase
K8Z39_RS07135	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z39_RS07145	COG1187	pseudouridine synthase activity
K8Z39_RS07150	COG1114	Component of the transport system for branched-chain amino acids
K8Z39_RS07155	COG5386	Cell surface protein
K8Z39_RS07165	COG5386	Cell surface protein
K8Z39_RS07180	COG1120	ATPase activity
K8Z39_RS07185	COG4509	Sortase family
K8Z39_RS07195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K8Z39_RS07200	COG4895	conserved protein (DUF2196)
K8Z39_RS07210	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS07215	COG2205	protein histidine kinase activity
K8Z39_RS07220	COG1131	(ABC) transporter
K8Z39_RS07250	COG2318	DinB family
K8Z39_RS07280	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_RS07285	COG1309	transcriptional regulator
K8Z39_RS07290	COG1024	Enoyl-CoA hydratase
K8Z39_RS07295	COG2086	electron transfer activity
K8Z39_RS07300	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K8Z39_RS07305	COG3118	belongs to the thioredoxin family
K8Z39_RS07315	COG1719	4-vinyl reductase, 4VR
K8Z39_RS07320	COG2009	succinate dehydrogenase
K8Z39_RS07325	COG1053	succinate dehydrogenase
K8Z39_RS07330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K8Z39_RS07335	COG0824	Thioesterase
K8Z39_RS07340	COG1876	peptidase activity
K8Z39_RS07345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z39_RS07350	COG1360	Flagellar Motor Protein
K8Z39_RS07355	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
K8Z39_RS07360	COG4152	abc transporter atp-binding protein
K8Z39_RS07365	COG1668	transmembrane transport
K8Z39_RS07370	COG1959	2 iron, 2 sulfur cluster binding
K8Z39_RS07380	COG0697	spore germination
K8Z39_RS07385	COG1396	sequence-specific DNA binding
K8Z39_RS07390	COG1983	PspC domain protein
K8Z39_RS07395	COG0402	S-adenosylhomocysteine deaminase activity
K8Z39_RS07400	COG2233	PERMEase
K8Z39_RS07405	COG2197	response regulator
K8Z39_RS07420	COG5401	PFAM Sporulation and spore germination
K8Z39_RS07435	COG0622	Phosphoesterase
K8Z39_RS07575	COG1067	ATP-dependent peptidase activity
K8Z39_RS07575	COG0470	DNA polymerase III
K8Z39_RS07590	COG1764	response to oxidative stress
K8Z39_RS07595	COG1846	Transcriptional regulator
K8Z39_RS07605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z39_RS07615	COG1587	Uroporphyrinogen-III synthase
K8Z39_RS07620	COG0113	porphobilinogen synthase activity
K8Z39_RS07630	COG1388	LysM domain
K8Z39_RS07645	COG0285	dihydrofolate synthase activity
K8Z39_RS07665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z39_RS07685	COG3646	Phage regulatory protein
K8Z39_RS07765	COG3331	DNA recombination
K8Z39_RS07775	COG1595	DNA-templated transcription, initiation
K8Z39_RS07890	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS07945	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K8Z39_RS07970	COG1077	Cell shape determining protein MreB Mrl
K8Z39_RS07990	COG2894	cell division
K8Z39_RS07995	COG0739	heme binding
K8Z39_RS08000	COG1994	Peptidase M50
K8Z39_RS08005	COG1530	ribonuclease E activity
K8Z39_RS08015	COG2868	ribosomal protein
K8Z39_RS08025	COG3290	protein histidine kinase activity
K8Z39_RS08035	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS08040	COG5002	protein histidine kinase activity
K8Z39_RS08045	COG1136	(ABC) transporter
K8Z39_RS08050	COG0577	efflux transmembrane transporter activity
K8Z39_RS08055	COG0577	efflux transmembrane transporter activity
K8Z39_RS08060	COG0077	Prephenate dehydratase
K8Z39_RS08065	COG2258	MOSC domain
K8Z39_RS08070	COG1827	regulation of RNA biosynthetic process
K8Z39_RS08075	COG1104	cysteine desulfurase activity
K8Z39_RS08080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K8Z39_RS08085	COG0157	Belongs to the NadC ModD family
K8Z39_RS08115	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K8Z39_RS08145	COG1862	Preprotein translocase
K8Z39_RS08155	COG2323	membrane
K8Z39_RS08160	COG2244	polysaccharide biosynthetic process
K8Z39_RS08170	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z39_RS08170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z39_RS08175	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z39_RS08180	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K8Z39_RS08180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K8Z39_RS08190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K8Z39_RS08215	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K8Z39_RS08225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K8Z39_RS08230	COG1959	2 iron, 2 sulfur cluster binding
K8Z39_RS08235	COG1104	cysteine desulfurase activity
K8Z39_RS08250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K8Z39_RS08270	COG0628	permease
K8Z39_RS08300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K8Z39_RS08305	COG4122	O-methyltransferase activity
K8Z39_RS08310	COG0826	peptidase U32
K8Z39_RS08315	COG0826	peptidase U32
K8Z39_RS08325	COG0582	viral genome integration into host DNA
K8Z39_RS08335	COG1396	sequence-specific DNA binding
K8Z39_RS08445	COG3331	DNA recombination
K8Z39_RS08505	COG3728	DNA packaging
K8Z39_RS08505	COG5484	DNA packaging
K8Z39_RS08600	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z39_RS08610	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS08610	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_RS08610	COG1388	LysM domain
K8Z39_RS08690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z39_RS08695	COG0626	cystathionine gamma-synthase activity
K8Z39_RS08700	COG1454	alcohol dehydrogenase
K8Z39_RS08700	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_RS08710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_RS08750	COG2259	Doxx family
K8Z39_RS08755	COG2514	catechol 2,3-dioxygenase activity
K8Z39_RS08765	COG3186	Phenylalanine-4-hydroxylase
K8Z39_RS08810	COG2267	carboxylic ester hydrolase activity
K8Z39_RS08820	COG1785	Belongs to the alkaline phosphatase family
K8Z39_RS08830	COG2357	RelA SpoT domain protein
K8Z39_RS08835	COG0778	Nitroreductase
K8Z39_RS08870	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
K8Z39_RS08875	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K8Z39_RS08885	COG1534	Rna-binding protein
K8Z39_RS08895	COG1713	HD superfamily hydrolase involved in NAD metabolism
K8Z39_RS08900	COG0799	negative regulation of ribosome biogenesis
K8Z39_RS08905	COG2226	methyltransferase
K8Z39_RS08910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z39_RS08915	COG1555	photosystem II stabilization
K8Z39_RS08915	COG1596	polysaccharide export
K8Z39_RS08920	COG2131	deaminase
K8Z39_RS08925	COG0658	competence protein
K8Z39_RS08925	COG2333	competence protein COMEC
K8Z39_RS08935	COG1466	dna polymerase III delta subunit
K8Z39_RS08960	COG1733	regulation of RNA biosynthetic process
K8Z39_RS08965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z39_RS08995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K8Z39_RS09000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K8Z39_RS09005	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K8Z39_RS09010	COG1610	YqeY-like protein
K8Z39_RS09025	COG1702	phosphate starvation-inducible protein PhoH
K8Z39_RS09030	COG1480	7TM receptor with intracellular HD hydrolase
K8Z39_RS09040	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K8Z39_RS09045	COG0295	cytidine deaminase activity
K8Z39_RS09050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K8Z39_RS09065	COG0517	IMP dehydrogenase activity
K8Z39_RS09080	COG0358	DNA primase activity
K8Z39_RS09085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K8Z39_RS09095	COG2384	SAM-dependent methyltransferase
K8Z39_RS09100	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K8Z39_RS09130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_RS09135	COG1121	(ABC) transporter
K8Z39_RS09140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K8Z39_RS09145	COG0735	belongs to the Fur family
K8Z39_RS09160	COG5521	maltodextrose utilization protein MalA
K8Z39_RS09170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z39_RS09175	COG0477	Major facilitator Superfamily
K8Z39_RS09180	COG0768	penicillin binding
K8Z39_RS09190	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z39_RS09195	COG0573	inorganic phosphate transmembrane transporter activity
K8Z39_RS09200	COG0573	inorganic phosphate transmembrane transporter activity
K8Z39_RS09210	COG0704	Plays a role in the regulation of phosphate uptake
K8Z39_RS09215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z39_RS09220	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K8Z39_RS09225	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K8Z39_RS09230	COG4483	Protein conserved in bacteria
K8Z39_RS09235	COG1940	carbohydrate kinase activity
K8Z39_RS09245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_RS09265	COG0626	cystathionine gamma-synthase activity
K8Z39_RS09270	COG0626	cystathionine gamma-synthase activity
K8Z39_RS09275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K8Z39_RS09275	COG0646	methionine synthase
K8Z39_RS09280	COG1410	methionine synthase
K8Z39_RS09280	COG0646	methionine synthase
K8Z39_RS09335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K8Z39_RS09340	COG1459	type II secretion system
K8Z39_RS09385	COG1396	sequence-specific DNA binding
K8Z39_RS09395	COG3646	Phage regulatory protein
K8Z39_RS09420	COG1484	DNA-dependent DNA replication
K8Z39_RS09430	COG2002	toxin-antitoxin pair type II binding
K8Z39_RS09490	COG0582	viral genome integration into host DNA
K8Z39_RS09545	COG0740	serine-type endopeptidase activity
K8Z39_RS09620	COG4824	toxin secretion phage lysis holin
K8Z39_RS09705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z39_RS09735	COG1725	Transcriptional regulator
K8Z39_RS09740	COG1131	(ABC) transporter
K8Z39_RS09770	COG2076	Multidrug Resistance protein
K8Z39_RS09775	COG2076	Multidrug Resistance protein
K8Z39_RS09785	COG1609	Transcriptional regulator
K8Z39_RS09795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z39_RS09835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K8Z39_RS09845	COG3872	metal-dependent enzyme
K8Z39_RS09860	COG0006	proline dipeptidase activity
K8Z39_RS09885	COG3854	ATPases associated with a variety of cellular activities
K8Z39_RS09930	COG0511	ligase activity, forming carbon-carbon bonds
K8Z39_RS09935	COG0439	Biotin carboxylase
K8Z39_RS09940	COG1302	Protein conserved in bacteria
K8Z39_RS09965	COG0142	geranyltranstransferase activity
K8Z39_RS09975	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
K8Z39_RS09985	COG0497	DNA recombination
K8Z39_RS09990	COG0750	zinc metalloprotease
K8Z39_RS10005	COG3093	addiction module antidote protein HigA
K8Z39_RS10010	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z39_RS10020	COG3829	transcription factor binding
K8Z39_RS10020	COG3290	protein histidine kinase activity
K8Z39_RS10025	COG0280	phosphate acetyltransferase
K8Z39_RS10040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z39_RS10045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z39_RS10050	COG0022	dehydrogenase e1 component
K8Z39_RS10055	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z39_RS10065	COG0772	Belongs to the SEDS family
K8Z39_RS10070	COG2323	membrane
K8Z39_RS10090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z39_RS10095	COG0765	amino acid transport
K8Z39_RS10100	COG1126	abc transporter atp-binding protein
K8Z39_RS10105	COG4129	membrane
K8Z39_RS10110	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z39_RS10125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS10130	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z39_RS10140	COG1285	pathogenesis
K8Z39_RS10170	COG1760	l-serine dehydratase
K8Z39_RS10175	COG1760	l-serine dehydratase
K8Z39_RS10180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z39_RS10185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_RS10190	COG0300	oxidoreductase activity
K8Z39_RS10235	COG1522	sequence-specific DNA binding
K8Z39_RS10245	COG0737	Belongs to the 5'-nucleotidase family
K8Z39_RS10250	COG1757	Na H antiporter
K8Z39_RS10260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z39_RS10275	COG2226	methyltransferase
K8Z39_RS10275	COG1073	alpha beta
K8Z39_RS10305	COG0307	riboflavin synthase, alpha
K8Z39_RS10310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z39_RS10310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z39_RS10325	COG1073	alpha beta
K8Z39_RS10330	COG0456	acetyltransferase
K8Z39_RS10335	COG1609	Transcriptional regulator
K8Z39_RS10340	COG2056	Na+-H+ antiporter family
K8Z39_RS10345	COG0596	Alpha beta hydrolase
K8Z39_RS10375	COG0456	acetyltransferase
K8Z39_RS10375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z39_RS10380	COG0656	L-ascorbic acid biosynthetic process
K8Z39_RS10385	COG0667	Aldo Keto reductase
K8Z39_RS10405	COG1300	Membrane
K8Z39_RS10410	COG0735	belongs to the Fur family
K8Z39_RS10420	COG4974	Belongs to the 'phage' integrase family
K8Z39_RS10445	COG0598	Magnesium transport protein CorA
K8Z39_RS10460	COG1846	Transcriptional regulator
K8Z39_RS10475	COG1131	(ABC) transporter
K8Z39_RS10480	COG1725	Transcriptional regulator
K8Z39_RS10485	COG1686	Belongs to the peptidase S11 family
K8Z39_RS10530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z39_RS10545	COG0697	spore germination
K8Z39_RS10550	COG0561	phosphatase activity
K8Z39_RS10555	COG4086	secreted protein
K8Z39_RS10560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K8Z39_RS10565	COG0456	acetyltransferase
K8Z39_RS10570	COG1547	Domain of unknown function (DUF309)
K8Z39_RS10595	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K8Z39_RS10605	COG2188	Transcriptional regulator
K8Z39_RS10615	COG3711	transcriptional antiterminator
K8Z39_RS10620	COG1263	PTS System
K8Z39_RS10620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z39_RS10620	COG2190	(PTS) system
K8Z39_RS10645	COG0778	Nitroreductase
K8Z39_RS10650	COG2199	diguanylate cyclase activity
K8Z39_RS10660	COG2084	Dehydrogenase
K8Z39_RS10695	COG0436	Aminotransferase
K8Z39_RS10700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K8Z39_RS10720	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS10725	COG1695	Transcriptional regulator
K8Z39_RS10760	COG0183	Belongs to the thiolase family
K8Z39_RS10795	COG3842	ATPase activity
K8Z39_RS10800	COG0366	Alpha amylase catalytic
K8Z39_RS10810	COG2182	Extracellular solute-binding protein
K8Z39_RS10815	COG1175	transmembrane transport
K8Z39_RS10820	COG3833	ABC-type maltose transport systems, permease component
K8Z39_RS10825	COG1609	Transcriptional regulator
K8Z39_RS10830	COG0436	Aminotransferase
K8Z39_RS10840	COG2205	protein histidine kinase activity
K8Z39_RS10850	COG3209	COG3209 Rhs family protein
K8Z39_RS10870	COG2814	Major facilitator Superfamily
K8Z39_RS10915	COG1408	metallophosphoesterase
K8Z39_RS10920	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS10925	COG2200	EAL domain
K8Z39_RS10940	COG4703	Protein of unknown function (DUF1797)
K8Z39_RS10950	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
K8Z39_RS10960	COG0517	IMP dehydrogenase activity
K8Z39_RS10965	COG0583	DNA-binding transcription factor activity
K8Z39_RS10985	COG0569	domain protein
K8Z39_RS10990	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z39_RS11000	COG0561	phosphatase activity
K8Z39_RS11015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z39_RS11020	COG0022	dehydrogenase e1 component
K8Z39_RS11070	COG1982	Orn Lys Arg decarboxylase major
K8Z39_RS11090	COG0483	inositol monophosphate 1-phosphatase activity
K8Z39_RS11100	COG1217	gtp-binding protein TYPA
K8Z39_RS11115	COG4896	Protein conserved in bacteria
K8Z39_RS11125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K8Z39_RS11130	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K8Z39_RS11140	COG0772	Belongs to the SEDS family
K8Z39_RS11145	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K8Z39_RS11180	COG3336	cytochrome c oxidase
K8Z39_RS11195	COG2340	Cysteine-rich secretory protein family
K8Z39_RS11210	COG0406	alpha-ribazole phosphatase activity
K8Z39_RS11215	COG3679	Belongs to the UPF0342 family
K8Z39_RS11230	COG0742	ribosomal rna small subunit methyltransferase
K8Z39_RS11240	COG3314	Sporulation integral membrane protein YlbJ
K8Z39_RS11245	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z39_RS11250	COG3480	Lon protease (S16) C-terminal proteolytic domain
K8Z39_RS11260	COG0582	viral genome integration into host DNA
K8Z39_RS11300	COG1396	sequence-specific DNA binding
K8Z39_RS11340	COG2002	toxin-antitoxin pair type II binding
K8Z39_RS11395	COG0582	viral genome integration into host DNA
K8Z39_RS11450	COG0740	serine-type endopeptidase activity
K8Z39_RS11525	COG4824	toxin secretion phage lysis holin
K8Z39_RS11560	COG1399	metal-binding, possibly nucleic acid-binding protein
K8Z39_RS11565	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K8Z39_RS11585	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z39_RS11605	COG0768	penicillin binding
K8Z39_RS11610	COG0768	penicillin binding
K8Z39_RS11630	COG0772	Belongs to the SEDS family
K8Z39_RS11650	COG0849	cell division
K8Z39_RS11655	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K8Z39_RS11665	COG1191	sigma factor activity
K8Z39_RS11670	COG1191	sigma factor activity
K8Z39_RS11675	COG1873	PFAM PRC-barrel domain
K8Z39_RS11685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K8Z39_RS11695	COG0762	integral membrane protein
K8Z39_RS11700	COG2302	S4 RNA-binding domain
K8Z39_RS11705	COG3599	regulation of cell shape
K8Z39_RS11725	COG0564	pseudouridine synthase activity
K8Z39_RS11785	COG3069	C4-dicarboxylate transmembrane transporter activity
K8Z39_RS11800	COG0006	proline dipeptidase activity
K8Z39_RS11810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z39_RS11815	COG1561	YicC-like family, N-terminal region
K8Z39_RS11835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z39_RS11840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K8Z39_RS11855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K8Z39_RS11855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K8Z39_RS11865	COG0631	protein serine/threonine phosphatase activity
K8Z39_RS11870	COG0515	serine threonine protein kinase
K8Z39_RS11870	COG2815	serine threonine protein kinase
K8Z39_RS11880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K8Z39_RS11885	COG1564	THIamine pyrophosphokinase
K8Z39_RS11900	COG1302	Protein conserved in bacteria
K8Z39_RS11905	COG1461	Dihydroxyacetone kinase
K8Z39_RS11910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K8Z39_RS11925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K8Z39_RS11930	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS11935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z39_RS11945	COG1196	nuclear chromosome segregation
K8Z39_RS11950	COG0552	protein localization to endoplasmic reticulum
K8Z39_RS11960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K8Z39_RS11970	COG1837	Belongs to the UPF0109 family
K8Z39_RS12010	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K8Z39_RS12015	COG0758	DNA mediated transformation
K8Z39_RS12020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z39_RS12030	COG4974	Belongs to the 'phage' integrase family
K8Z39_RS12080	COG4589	Belongs to the CDS family
K8Z39_RS12090	COG0750	zinc metalloprotease
K8Z39_RS12110	COG0195	Participates in both transcription termination and antitermination
K8Z39_RS12115	COG2740	Nucleic-acid-binding protein implicated in transcription termination
K8Z39_RS12120	COG1358	cellular component organization or biogenesis
K8Z39_RS12130	COG1550	Protein conserved in bacteria
K8Z39_RS12135	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K8Z39_RS12145	COG0196	riboflavin kinase activity
K8Z39_RS12160	COG0726	polysaccharide deacetylase
K8Z39_RS12165	COG0612	Peptidase, M16
K8Z39_RS12170	COG1873	PFAM PRC-barrel domain
K8Z39_RS12175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z39_RS12180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z39_RS12185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z39_RS12190	COG0527	aspartate kinase activity
K8Z39_RS12200	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z39_RS12210	COG0740	serine-type endopeptidase activity
K8Z39_RS12225	COG2188	Transcriptional regulator
K8Z39_RS12230	COG1744	ABC transporter substrate-binding protein PnrA-like
K8Z39_RS12235	COG3845	ABC transporter
K8Z39_RS12240	COG4603	Belongs to the binding-protein-dependent transport system permease family
K8Z39_RS12245	COG1079	Belongs to the binding-protein-dependent transport system permease family
K8Z39_RS12250	COG0612	Peptidase, M16
K8Z39_RS12255	COG0612	Peptidase, M16
K8Z39_RS12260	COG0300	oxidoreductase activity
K8Z39_RS12275	COG1426	Protein conserved in bacteria
K8Z39_RS12280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K8Z39_RS12300	COG1692	metallophosphoesterase
K8Z39_RS12305	COG2359	stage V sporulation protein S
K8Z39_RS12315	COG0674	pyruvate-flavodoxin oxidoreductase activity
K8Z39_RS12315	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K8Z39_RS12320	COG1013	pyruvate-flavodoxin oxidoreductase activity
K8Z39_RS12330	COG4550	Control of competence regulator ComK, YlbF/YmcA
K8Z39_RS12355	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z39_RS12360	COG1368	sulfuric ester hydrolase activity
K8Z39_RS12370	COG3773	Cell wall hydrolase
K8Z39_RS12375	COG1404	Belongs to the peptidase S8 family
K8Z39_RS12380	COG0823	Involved in the tonB-independent uptake of proteins
K8Z39_RS12385	COG2723	6-phospho-beta-galactosidase activity
K8Z39_RS12390	COG2188	Transcriptional regulator
K8Z39_RS12400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_RS12410	COG1346	cytolysis
K8Z39_RS12430	COG1086	Polysaccharide biosynthesis protein
K8Z39_RS12450	COG3300	MHYT domain
K8Z39_RS12450	COG5001	Diguanylate cyclase
K8Z39_RS12455	COG2267	carboxylic ester hydrolase activity
K8Z39_RS12475	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z39_RS12480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z39_RS12485	COG2169	Transcriptional regulator
K8Z39_RS12495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_RS12500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_RS12505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_RS12510	COG1120	ATPase activity
K8Z39_RS12515	COG2819	hydrolase of the alpha beta superfamily
K8Z39_RS12525	COG1937	Protein conserved in bacteria
K8Z39_RS12530	COG2608	mercury ion transmembrane transporter activity
K8Z39_RS12535	COG2217	Heavy metal translocating P-type atpase
K8Z39_RS12550	COG2116	formate transmembrane transporter activity
K8Z39_RS12565	COG1113	amino acid transport
K8Z39_RS12575	COG2322	membrane
K8Z39_RS12580	COG1979	alcohol dehydrogenase
K8Z39_RS12585	COG1349	DNA-binding transcription factor activity
K8Z39_RS12590	COG1105	Belongs to the carbohydrate kinase PfkB family
K8Z39_RS12595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z39_RS12595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z39_RS12595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z39_RS12605	COG1388	LysM domain
K8Z39_RS12605	COG3584	3D domain protein
K8Z39_RS12635	COG0464	growth
K8Z39_RS12645	COG2860	membrane
K8Z39_RS12650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z39_RS12655	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
K8Z39_RS12660	COG0789	Transcriptional regulator
K8Z39_RS12665	COG0174	glutamine synthetase
K8Z39_RS12675	COG1695	Transcriptional regulator
K8Z39_RS12695	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z39_RS12720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z39_RS12755	COG1132	(ABC) transporter
K8Z39_RS12760	COG1132	(ABC) transporter
K8Z39_RS12785	COG0730	response to heat
K8Z39_RS12800	COG1346	cytolysis
K8Z39_RS12810	COG0583	DNA-binding transcription factor activity
K8Z39_RS12825	COG1131	(ABC) transporter
K8Z39_RS12840	COG1473	amidohydrolase
K8Z39_RS12850	COG0785	Cytochrome C biogenesis protein
K8Z39_RS12855	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z39_RS12880	COG2226	methyltransferase
K8Z39_RS12905	COG0010	Belongs to the arginase family
K8Z39_RS12910	COG1329	Transcriptional regulator
K8Z39_RS12915	COG1902	pentaerythritol trinitrate reductase activity
K8Z39_RS12920	COG0069	glutamate synthase activity
K8Z39_RS12930	COG0346	lactoylglutathione lyase activity
K8Z39_RS12935	COG0400	carboxylic ester hydrolase activity
K8Z39_RS12940	COG5002	protein histidine kinase activity
K8Z39_RS12950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_RS12990	COG0830	nickel cation binding
K8Z39_RS13010	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
K8Z39_RS13035	COG1396	sequence-specific DNA binding
K8Z39_RS13040	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_RS13045	COG1268	BioY protein
K8Z39_RS13050	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_RS13055	COG0183	Belongs to the thiolase family
K8Z39_RS13070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z39_RS13080	COG2211	Major facilitator Superfamily
K8Z39_RS13110	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K8Z39_RS13120	COG1132	(ABC) transporter
K8Z39_RS13135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z39_RS13170	COG0824	Thioesterase
K8Z39_RS13175	COG4841	protein insertion into membrane
K8Z39_RS13185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K8Z39_RS13185	COG1328	CTP reductase activity
K8Z39_RS13195	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS13200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z39_RS13205	COG1832	CoA-binding protein
K8Z39_RS13210	COG0187	DNA topoisomerase II activity
K8Z39_RS13215	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z39_RS13220	COG0673	inositol 2-dehydrogenase activity
K8Z39_RS13240	COG1131	(ABC) transporter
K8Z39_RS13250	COG1595	DNA-templated transcription, initiation
K8Z39_RS13260	COG1316	TRANSCRIPTIONal
K8Z39_RS13265	COG4166	transmembrane transport
K8Z39_RS13270	COG4166	transmembrane transport
K8Z39_RS13275	COG4166	transmembrane transport
K8Z39_RS13280	COG2226	methyltransferase
K8Z39_RS13315	COG0531	amino acid
K8Z39_RS13330	COG0697	spore germination
K8Z39_RS13335	COG3383	formate dehydrogenase (NAD+) activity
K8Z39_RS13340	COG2427	Protein of unknown function (DUF1641)
K8Z39_RS13345	COG5609	conserved protein (DUF2294)
K8Z39_RS13350	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z39_RS13360	COG2116	formate transmembrane transporter activity
K8Z39_RS13365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z39_RS13370	COG0303	'Molybdopterin
K8Z39_RS13375	COG0314	molybdopterin synthase activity
K8Z39_RS13385	COG0489	protein tyrosine kinase activity
K8Z39_RS13400	COG3326	Membrane
K8Z39_RS13405	COG2962	Rard protein
K8Z39_RS13410	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
K8Z39_RS13415	COG1657	PFAM Prenyltransferase squalene oxidase
K8Z39_RS13425	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS13430	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_RS13440	COG4145	pantothenate transmembrane transporter activity
K8Z39_RS13455	COG0165	Argininosuccinate lyase
K8Z39_RS13465	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS13500	COG0716	FMN binding
K8Z39_RS13535	COG2720	vancomycin resistance protein
K8Z39_RS13540	COG2514	catechol 2,3-dioxygenase activity
K8Z39_RS13550	COG1285	pathogenesis
K8Z39_RS13560	COG3852	Histidine kinase
K8Z39_RS13585	COG0488	(ABC) transporter
K8Z39_RS13615	COG1404	Belongs to the peptidase S8 family
K8Z39_RS13650	COG0457	Tetratricopeptide repeat
K8Z39_RS13660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z39_RS13670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z39_RS13700	COG0697	spore germination
K8Z39_RS13710	COG3397	chitin binding
K8Z39_RS13715	COG0823	Involved in the tonB-independent uptake of proteins
K8Z39_RS13725	COG1252	NADH dehydrogenase
K8Z39_RS13730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_RS13730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z39_RS13735	COG1183	phosphatidylcholine synthase activity
K8Z39_RS13760	COG0277	FAD linked oxidase domain protein
K8Z39_RS13765	COG0385	Bile acid
K8Z39_RS13775	COG0457	Tetratricopeptide repeat
K8Z39_RS13785	COG0604	alcohol dehydrogenase
K8Z39_RS13790	COG0640	Transcriptional regulator
K8Z39_RS13800	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z39_RS13830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z39_RS13855	COG1164	Oligoendopeptidase f
K8Z39_RS13860	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z39_RS13870	COG1193	negative regulation of DNA recombination
K8Z39_RS13885	COG2890	protein-(glutamine-N5) methyltransferase activity
K8Z39_RS13895	COG0583	DNA-binding transcription factor activity
K8Z39_RS13910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS13935	COG3739	integral membrane protein
K8Z39_RS13940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_RS13945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_RS13950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_RS13955	COG1247	-acetyltransferase
K8Z39_RS13965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z39_RS13970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K8Z39_RS14005	COG2814	Major facilitator Superfamily
K8Z39_RS14010	COG1113	amino acid transport
K8Z39_RS14075	COG1151	hydroxylamine reductase activity
K8Z39_RS14130	COG1191	sigma factor activity
K8Z39_RS14155	COG1733	regulation of RNA biosynthetic process
K8Z39_RS14160	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z39_RS14165	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_RS14185	COG0384	phenazine biosynthesis protein PhzF
K8Z39_RS14205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_RS14225	COG0673	inositol 2-dehydrogenase activity
K8Z39_RS14230	COG2188	Transcriptional regulator
K8Z39_RS14260	COG0814	amino acid
K8Z39_RS14275	COG1733	regulation of RNA biosynthetic process
K8Z39_RS14280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8Z39_RS14280	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8Z39_RS14285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z39_RS14285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z39_RS14295	COG0840	transmembrane signaling receptor activity
K8Z39_RS14320	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K8Z39_RS14325	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K8Z39_RS14330	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z39_RS14335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K8Z39_RS14345	COG1070	Carbohydrate kinase
K8Z39_RS14350	COG2706	6-phosphogluconolactonase activity
K8Z39_RS14355	COG3813	Protein conserved in bacteria
K8Z39_RS14360	COG1357	PFAM Pentapeptide repeats (8 copies)
K8Z39_RS14370	COG0697	spore germination
K8Z39_RS14400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z39_RS14410	COG0789	Transcriptional regulator
K8Z39_RS14415	COG1253	flavin adenine dinucleotide binding
K8Z39_RS14445	COG0477	Major facilitator Superfamily
K8Z39_RS14455	COG0500	methyltransferase
K8Z39_RS14515	COG2365	Tyrosine phosphatase family
K8Z39_RS14525	COG1011	Hydrolase
K8Z39_RS14550	COG1131	(ABC) transporter
K8Z39_RS14560	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS14580	COG0469	pyruvate kinase activity
K8Z39_RS14590	COG0778	Nitroreductase
K8Z39_RS14595	COG1733	regulation of RNA biosynthetic process
K8Z39_RS14605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K8Z39_RS14625	COG1288	antiporter activity
K8Z39_RS14680	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z39_RS14690	COG2031	fatty acid transporter
K8Z39_RS14705	COG2814	Major facilitator Superfamily
K8Z39_RS14710	COG1846	Transcriptional regulator
K8Z39_RS14725	COG0477	Major facilitator Superfamily
K8Z39_RS14735	COG2843	Capsule synthesis protein
K8Z39_RS14740	COG1876	peptidase activity
K8Z39_RS14765	COG5444	nuclease activity
K8Z39_RS14855	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_RS14855	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS14870	COG3831	ATPase activity
K8Z39_RS14900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K8Z39_RS14930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_RS14940	COG3850	Histidine kinase
K8Z39_RS14940	COG5002	protein histidine kinase activity
K8Z39_RS14945	COG0577	efflux transmembrane transporter activity
K8Z39_RS14965	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K8Z39_RS14975	COG1690	Belongs to the RtcB family
K8Z39_RS14985	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K8Z39_RS15000	COG2814	Major facilitator Superfamily
K8Z39_RS15095	COG0346	lactoylglutathione lyase activity
K8Z39_RS15115	COG1522	sequence-specific DNA binding
K8Z39_RS15120	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS15125	COG1309	transcriptional regulator
K8Z39_RS15130	COG2814	Major facilitator Superfamily
K8Z39_RS15135	COG0640	Transcriptional regulator
K8Z39_RS15140	COG0346	lactoylglutathione lyase activity
K8Z39_RS15145	COG0798	PFAM Bile acid sodium symporter
K8Z39_RS15155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS15165	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z39_RS15170	COG0456	acetyltransferase
K8Z39_RS15180	COG5609	conserved protein (DUF2294)
K8Z39_RS15185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z39_RS15195	COG0288	reversible hydration of carbon dioxide
K8Z39_RS15200	COG0657	acetylesterase activity
K8Z39_RS15275	COG0598	Magnesium transport protein CorA
K8Z39_RS15320	COG0583	DNA-binding transcription factor activity
K8Z39_RS15325	COG2801	Transposase and inactivated derivatives
K8Z39_RS15350	COG1335	isochorismatase
K8Z39_RS15355	COG2267	carboxylic ester hydrolase activity
K8Z39_RS15360	COG0737	Belongs to the 5'-nucleotidase family
K8Z39_RS15380	COG2207	Transcriptional regulator
K8Z39_RS15410	COG5002	protein histidine kinase activity
K8Z39_RS15420	COG1063	alcohol dehydrogenase
K8Z39_RS15440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_RS15450	COG1522	sequence-specific DNA binding
K8Z39_RS15470	COG3848	Pyruvate phosphate dikinase
K8Z39_RS15470	COG0574	Belongs to the PEP-utilizing enzyme family
K8Z39_RS15495	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
K8Z39_RS15505	COG0454	-acetyltransferase
K8Z39_RS15515	COG3314	Sporulation integral membrane protein YlbJ
K8Z39_RS15530	COG1960	acyl-CoA dehydrogenase activity
K8Z39_RS15540	COG0640	Transcriptional regulator
K8Z39_RS15545	COG3142	Participates in the control of copper homeostasis
K8Z39_RS15555	COG1414	Transcriptional regulator
K8Z39_RS15560	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K8Z39_RS15565	COG1984	allophanate hydrolase subunit 2
K8Z39_RS15600	COG0768	penicillin binding
K8Z39_RS15645	COG0833	amino acid
K8Z39_RS15655	COG0730	response to heat
K8Z39_RS15695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_RS15700	COG0697	spore germination
K8Z39_RS15715	COG0456	acetyltransferase
K8Z39_RS15725	COG0590	tRNA wobble adenosine to inosine editing
K8Z39_RS15725	COG0037	tRNA processing
K8Z39_RS15750	COG4884	unkown
K8Z39_RS15750	COG3831	ATPase activity
K8Z39_RS15770	COG1846	Transcriptional regulator
K8Z39_RS15775	COG0778	Nitroreductase
K8Z39_RS15860	COG0714	Associated with various cellular activities
K8Z39_RS15900	COG0753	catalase activity
K8Z39_RS15905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K8Z39_RS15925	COG0463	Glycosyl transferase, family 2
K8Z39_RS15970	COG0714	Associated with various cellular activities
K8Z39_RS15995	COG0346	lactoylglutathione lyase activity
K8Z39_RS16000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS16020	COG3655	Transcriptional regulator
K8Z39_RS16030	COG1785	Belongs to the alkaline phosphatase family
K8Z39_RS16035	COG2720	vancomycin resistance protein
K8Z39_RS16055	COG0833	amino acid
K8Z39_RS16060	COG1414	Transcriptional regulator
K8Z39_RS16065	COG4187	Peptidase family M20/M25/M40
K8Z39_RS16070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z39_RS16090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_RS16110	COG2329	Antibiotic biosynthesis monooxygenase
K8Z39_RS16135	COG1070	Carbohydrate kinase
K8Z39_RS16140	COG2390	Transcriptional regulator
K8Z39_RS16150	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z39_RS16160	COG1879	ABC-type sugar transport system periplasmic component
K8Z39_RS16180	COG0277	FAD linked oxidase domain protein
K8Z39_RS16195	COG1388	LysM domain
K8Z39_RS16195	COG3584	3D domain protein
K8Z39_RS16240	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z39_RS16240	COG1605	Chorismate mutase
K8Z39_RS16255	COG0287	Prephenate dehydrogenase
K8Z39_RS16270	COG1309	transcriptional regulator
K8Z39_RS16290	COG0488	(ABC) transporter
K8Z39_RS16295	COG1368	sulfuric ester hydrolase activity
K8Z39_RS16305	COG0861	Integral membrane protein TerC family
K8Z39_RS16315	COG0346	lactoylglutathione lyase activity
K8Z39_RS16320	COG4912	Dna alkylation repair
K8Z39_RS16350	COG0697	spore germination
K8Z39_RS16370	COG2746	aminoglycoside 3-N-acetyltransferase activity
K8Z39_RS16400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z39_RS16405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z39_RS16410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z39_RS16425	COG0628	permease
K8Z39_RS16475	COG1131	(ABC) transporter
K8Z39_RS16490	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
K8Z39_RS16500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K8Z39_RS16505	COG0436	Aminotransferase
K8Z39_RS16540	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K8Z39_RS16555	COG2261	transglycosylase associated protein
K8Z39_RS16580	COG0477	Major facilitator Superfamily
K8Z39_RS16580	COG2814	Major facilitator Superfamily
K8Z39_RS16585	COG4533	DNA binding
K8Z39_RS16590	COG0789	Transcriptional regulator
K8Z39_RS16595	COG1664	Polymer-forming cytoskeletal
K8Z39_RS16605	COG2814	Major facilitator Superfamily
K8Z39_RS16650	COG1307	EDD domain protein, DegV family
K8Z39_RS16655	COG1164	Oligoendopeptidase f
K8Z39_RS16665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z39_RS16685	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS16690	COG3850	Histidine kinase
K8Z39_RS16690	COG5002	protein histidine kinase activity
K8Z39_RS16735	COG0667	Aldo Keto reductase
K8Z39_RS16750	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z39_RS16760	COG4166	transmembrane transport
K8Z39_RS16770	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z39_RS16780	COG0586	Pfam SNARE associated Golgi protein
K8Z39_RS16820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z39_RS16825	COG3938	Belongs to the proline racemase family
K8Z39_RS16835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K8Z39_RS16840	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_RS16845	COG1115	amino acid carrier protein
K8Z39_RS16850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K8Z39_RS16855	COG1162	GTPase activity
K8Z39_RS16870	COG3397	chitin binding
K8Z39_RS16885	COG4637	Psort location Cytoplasmic, score
K8Z39_RS16925	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z39_RS16930	COG2105	PFAM AIG2 family protein
K8Z39_RS16940	COG3973	AAA domain
K8Z39_RS16945	COG0456	acetyltransferase
K8Z39_RS16990	COG2315	Protein conserved in bacteria
K8Z39_RS16995	COG2226	methyltransferase
K8Z39_RS17000	COG2205	protein histidine kinase activity
K8Z39_RS17020	COG1819	glycosyl
K8Z39_RS17025	COG3397	chitin binding
K8Z39_RS17030	COG2153	protein acetylation
K8Z39_RS17060	COG0517	IMP dehydrogenase activity
K8Z39_RS17060	COG4175	Glycine betaine
K8Z39_RS17065	COG4176	ABC-type proline glycine betaine transport system permease component
K8Z39_RS17105	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z39_RS17105	COG0456	acetyltransferase
K8Z39_RS17110	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS17120	COG2814	Major facilitator Superfamily
K8Z39_RS17130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z39_RS17135	COG0022	dehydrogenase e1 component
K8Z39_RS17140	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z39_RS17145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z39_RS17160	COG1959	2 iron, 2 sulfur cluster binding
K8Z39_RS17195	COG3284	Transcriptional regulator
K8Z39_RS17225	COG1309	transcriptional regulator
K8Z39_RS17265	COG2959	enzyme of heme biosynthesis
K8Z39_RS17280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS17315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_RS17320	COG0697	spore germination
K8Z39_RS17325	COG0201	protein transport
K8Z39_RS17340	COG0737	Belongs to the 5'-nucleotidase family
K8Z39_RS17345	COG3227	Zinc metalloprotease (Elastase)
K8Z39_RS17350	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z39_RS17365	COG0076	glutamate decarboxylase activity
K8Z39_RS17370	COG0657	acetylesterase activity
K8Z39_RS17375	COG1073	alpha beta
K8Z39_RS17380	COG0577	efflux transmembrane transporter activity
K8Z39_RS17385	COG1136	(ABC) transporter
K8Z39_RS17400	COG5002	protein histidine kinase activity
K8Z39_RS17405	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS17410	COG1011	Hydrolase
K8Z39_RS17440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z39_RS17460	COG0322	excinuclease ABC activity
K8Z39_RS17500	COG4667	esterase of the alpha-beta hydrolase superfamily
K8Z39_RS17525	COG3878	Protein conserved in bacteria
K8Z39_RS17560	COG0592	DNA-directed DNA polymerase activity
K8Z39_RS17575	COG2223	nitrite transmembrane transporter activity
K8Z39_RS17585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z39_RS17620	COG0697	spore germination
K8Z39_RS17625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_RS17640	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z39_RS17655	COG2814	Major facilitator Superfamily
K8Z39_RS17660	COG2814	Major facilitator Superfamily
K8Z39_RS17715	COG0768	penicillin binding
K8Z39_RS17720	COG0671	phosphoesterase, PA-phosphatase related
K8Z39_RS17725	COG0604	alcohol dehydrogenase
K8Z39_RS17730	COG5002	protein histidine kinase activity
K8Z39_RS17735	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS17745	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z39_RS17760	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z39_RS17810	COG2205	protein histidine kinase activity
K8Z39_RS17835	COG1794	racemase activity, acting on amino acids and derivatives
K8Z39_RS17840	COG1819	glycosyl
K8Z39_RS17850	COG0768	penicillin binding
K8Z39_RS17855	COG5002	protein histidine kinase activity
K8Z39_RS17860	COG0561	phosphatase activity
K8Z39_RS17895	COG2124	cytochrome p450
K8Z39_RS17965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z39_RS17975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_RS17980	COG0460	homoserine dehydrogenase
K8Z39_RS18000	COG0577	efflux transmembrane transporter activity
K8Z39_RS18005	COG1136	(ABC) transporter
K8Z39_RS18015	COG0488	(ABC) transporter
K8Z39_RS18020	COG2205	protein histidine kinase activity
K8Z39_RS18025	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS18035	COG3773	Cell wall hydrolase
K8Z39_RS18040	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
K8Z39_RS18050	COG3386	PFAM SMP-30 Gluconolaconase
K8Z39_RS18060	COG0693	protein deglycase activity
K8Z39_RS18065	COG2323	membrane
K8Z39_RS18090	COG2368	4-hydroxyphenylacetate
K8Z39_RS18095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_RS18125	COG1131	(ABC) transporter
K8Z39_RS18135	COG0583	DNA-binding transcription factor activity
K8Z39_RS18140	COG1942	4-Oxalocrotonate Tautomerase
K8Z39_RS18185	COG2207	Transcriptional regulator
K8Z39_RS18190	COG3227	Zinc metalloprotease (Elastase)
K8Z39_RS18205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z39_RS18230	COG1686	Belongs to the peptidase S11 family
K8Z39_RS18250	COG0572	uridine kinase
K8Z39_RS18290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z39_RS18295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K8Z39_RS18300	COG1024	Enoyl-CoA hydratase
K8Z39_RS18305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K8Z39_RS18310	COG0511	ligase activity, forming carbon-carbon bonds
K8Z39_RS18315	COG0439	Biotin carboxylase
K8Z39_RS18320	COG1960	acyl-CoA dehydrogenase activity
K8Z39_RS18335	COG1309	transcriptional regulator
K8Z39_RS18375	COG4824	toxin secretion phage lysis holin
K8Z39_RS18450	COG0740	serine-type endopeptidase activity
K8Z39_RS18505	COG0582	viral genome integration into host DNA
K8Z39_RS18560	COG2002	toxin-antitoxin pair type II binding
K8Z39_RS18575	COG1484	DNA-dependent DNA replication
K8Z39_RS18605	COG3620	sequence-specific DNA binding
K8Z39_RS18615	COG0582	viral genome integration into host DNA
K8Z39_RS18625	COG1131	(ABC) transporter
K8Z39_RS18640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_RS18655	COG0768	penicillin binding
K8Z39_RS18660	COG0768	penicillin binding
K8Z39_RS18670	COG1595	DNA-templated transcription, initiation
K8Z39_RS18675	COG0768	penicillin binding
K8Z39_RS18685	COG2239	Acts as a magnesium transporter
K8Z39_RS18690	COG0772	Belongs to the SEDS family
K8Z39_RS18720	COG0076	glutamate decarboxylase activity
K8Z39_RS18730	COG1533	DNA photolyase activity
K8Z39_RS18750	COG0814	amino acid
K8Z39_RS18755	COG1760	l-serine dehydratase
K8Z39_RS18760	COG1760	l-serine dehydratase
K8Z39_RS18780	COG0367	asparagine synthase
K8Z39_RS18785	COG1309	transcriptional regulator
K8Z39_RS18805	COG1396	sequence-specific DNA binding
K8Z39_RS18915	COG2239	Acts as a magnesium transporter
K8Z39_RS18920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS18925	COG0741	lytic transglycosylase activity
K8Z39_RS18995	COG2814	Major facilitator Superfamily
K8Z39_RS19010	COG1686	Belongs to the peptidase S11 family
K8Z39_RS19015	COG0110	maltose O-acetyltransferase activity
K8Z39_RS19020	COG0730	response to heat
K8Z39_RS19030	COG2002	toxin-antitoxin pair type II binding
K8Z39_RS19055	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z39_RS19085	COG1846	Transcriptional regulator
K8Z39_RS19090	COG3961	Belongs to the TPP enzyme family
K8Z39_RS19095	COG2226	methyltransferase
K8Z39_RS19105	COG3615	Tellurite resistance protein tehB
K8Z39_RS19105	COG0500	methyltransferase
K8Z39_RS19130	COG1309	transcriptional regulator
K8Z39_RS19150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_RS19170	COG1846	Transcriptional regulator
K8Z39_RS19190	COG2971	BadF BadG BcrA BcrD
K8Z39_RS19215	COG1649	PFAM Uncharacterised BCR, COG1649
K8Z39_RS19240	COG1595	DNA-templated transcription, initiation
K8Z39_RS19245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z39_RS19315	COG1396	sequence-specific DNA binding
K8Z39_RS19340	COG1132	(ABC) transporter
K8Z39_RS19345	COG1132	(ABC) transporter
K8Z39_RS19360	COG2258	MOSC domain
K8Z39_RS19365	COG0583	DNA-binding transcription factor activity
K8Z39_RS19385	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z39_RS19390	COG0583	DNA-binding transcription factor activity
K8Z39_RS19425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS19435	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z39_RS19460	COG1247	-acetyltransferase
K8Z39_RS19495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_RS19520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z39_RS19560	COG0028	Belongs to the TPP enzyme family
K8Z39_RS19575	COG1136	(ABC) transporter
K8Z39_RS19580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z39_RS19585	COG1187	pseudouridine synthase activity
K8Z39_RS19590	COG2329	Antibiotic biosynthesis monooxygenase
K8Z39_RS19605	COG1115	amino acid carrier protein
K8Z39_RS19615	COG2318	DinB family
K8Z39_RS19625	COG0776	regulation of translation
K8Z39_RS19640	COG2814	Major facilitator Superfamily
K8Z39_RS19645	COG3251	PFAM MbtH domain protein
K8Z39_RS19650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z39_RS19655	COG3433	isochorismatase activity
K8Z39_RS19655	COG1535	isochorismatase
K8Z39_RS19660	COG1021	2,3-dihydroxybenzoate-AMP ligase
K8Z39_RS19665	COG1169	isochorismate synthase
K8Z39_RS19670	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS19675	COG2223	nitrite transmembrane transporter activity
K8Z39_RS19695	COG0419	ATPase involved in DNA repair
K8Z39_RS19700	COG0420	3'-5' exonuclease activity
K8Z39_RS19715	COG1024	Enoyl-CoA hydratase
K8Z39_RS19720	COG1280	lysine exporter protein (LysE YggA)
K8Z39_RS19730	COG2084	Dehydrogenase
K8Z39_RS19735	COG1960	acyl-CoA dehydrogenase activity
K8Z39_RS19740	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K8Z39_RS19745	COG2079	MmgE PrpD family protein
K8Z39_RS19750	COG0372	Belongs to the citrate synthase family
K8Z39_RS19755	COG4841	protein insertion into membrane
K8Z39_RS19760	COG2814	Major facilitator Superfamily
K8Z39_RS19770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z39_RS19770	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z39_RS19790	COG0300	oxidoreductase activity
K8Z39_RS19870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z39_RS19875	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z39_RS19880	COG0671	phosphoesterase, PA-phosphatase related
K8Z39_RS19890	COG3064	Membrane
K8Z39_RS19890	COG4991	sh3 domain protein
K8Z39_RS19890	COG0515	serine threonine protein kinase
K8Z39_RS19925	COG1509	lysine 2,3-aminomutase activity
K8Z39_RS19930	COG3829	transcription factor binding
K8Z39_RS19935	COG0456	acetyltransferase
K8Z39_RS19940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z39_RS19945	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K8Z39_RS19950	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K8Z39_RS19955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z39_RS19970	COG5506	Protein of unknown function (DUF1694)
K8Z39_RS19975	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_RS19980	COG1253	flavin adenine dinucleotide binding
K8Z39_RS20015	COG1174	glycine betaine transport
K8Z39_RS20020	COG0517	IMP dehydrogenase activity
K8Z39_RS20020	COG1125	glycine betaine transport
K8Z39_RS20055	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z39_RS20080	COG1064	alcohol dehydrogenase
K8Z39_RS20085	COG0384	phenazine biosynthesis protein PhzF
K8Z39_RS20090	COG1737	Transcriptional regulator
K8Z39_RS20095	COG2197	response regulator
K8Z39_RS20100	COG4585	Histidine kinase
K8Z39_RS20100	COG2203	Gaf domain
K8Z39_RS20105	COG0668	transmembrane transport
K8Z39_RS20120	COG1335	isochorismatase
K8Z39_RS20140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z39_RS20145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_RS20150	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS20165	COG0367	asparagine synthase
K8Z39_RS20170	COG0071	Belongs to the small heat shock protein (HSP20) family
K8Z39_RS20175	COG1999	signal sequence binding
K8Z39_RS20185	COG1307	EDD domain protein, DegV family
K8Z39_RS20195	COG0805	protein transport
K8Z39_RS20205	COG1272	protein, Hemolysin III
K8Z39_RS20215	COG0204	Acyl-transferase
K8Z39_RS20225	COG0768	penicillin binding
K8Z39_RS20240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z39_RS20255	COG0546	phosphoglycolate phosphatase activity
K8Z39_RS20265	COG4473	ABC transporter
K8Z39_RS20270	COG1131	(ABC) transporter
K8Z39_RS20280	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K8Z39_RS20285	COG3655	Transcriptional regulator
K8Z39_RS20295	COG0456	acetyltransferase
K8Z39_RS20305	COG1794	racemase activity, acting on amino acids and derivatives
K8Z39_RS20315	COG2610	gluconate transmembrane transporter activity
K8Z39_RS20345	COG0017	Asparaginyl-tRNA synthetase
K8Z39_RS20400	COG0018	arginyl-trna synthetase
K8Z39_RS20405	COG2521	methyltransferase
K8Z39_RS20405	COG2136	Putative SAM-dependent methyltransferase
K8Z39_RS20420	COG1413	lyase activity
K8Z39_RS20430	COG0629	single-stranded DNA binding
K8Z39_RS20450	COG1476	TRANSCRIPTIONal
K8Z39_RS20495	COG0488	(ABC) transporter
K8Z39_RS20500	COG1418	mRNA catabolic process
K8Z39_RS20515	COG0457	Tetratricopeptide repeat
K8Z39_RS20580	COG2359	stage V sporulation protein S
K8Z39_RS20615	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
K8Z39_RS20620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z39_RS20625	COG2146	nitrite reductase [NAD(P)H] activity
K8Z39_RS20630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K8Z39_RS20630	COG1587	Uroporphyrinogen-III synthase
K8Z39_RS20640	COG1648	precorrin-2 dehydrogenase activity
K8Z39_RS20650	COG2223	nitrite transmembrane transporter activity
K8Z39_RS20655	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
K8Z39_RS20660	COG0314	molybdopterin synthase activity
K8Z39_RS20665	COG0303	'Molybdopterin
K8Z39_RS20670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z39_RS20675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z39_RS20680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z39_RS20685	COG2181	nitrate reductase activity
K8Z39_RS20690	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
K8Z39_RS20695	COG1140	nitrate reductase beta subunit
K8Z39_RS20700	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
K8Z39_RS20705	COG0714	Associated with various cellular activities
K8Z39_RS20710	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
K8Z39_RS20720	COG0386	Belongs to the glutathione peroxidase family
K8Z39_RS20730	COG0426	domain, Protein
K8Z39_RS20730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z39_RS20745	COG1595	DNA-templated transcription, initiation
K8Z39_RS20760	COG0346	lactoylglutathione lyase activity
K8Z39_RS20765	COG1082	Xylose isomerase domain protein TIM barrel
K8Z39_RS20790	COG2226	methyltransferase
K8Z39_RS20815	COG3874	Sporulation protein YtfJ
K8Z39_RS20880	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z39_RS20915	COG0456	acetyltransferase
K8Z39_RS20945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_RS20950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_RS20955	COG1819	glycosyl
K8Z39_RS20975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z39_RS20990	COG0561	phosphatase activity
K8Z39_RS21000	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS21015	COG2211	Major facilitator Superfamily
K8Z39_RS21030	COG1876	peptidase activity
K8Z39_RS21040	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS21060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z39_RS21065	COG1114	Component of the transport system for branched-chain amino acids
K8Z39_RS21085	COG1253	flavin adenine dinucleotide binding
K8Z39_RS21090	COG2839	Protein conserved in bacteria
K8Z39_RS21095	COG0702	epimerase
K8Z39_RS21110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z39_RS21120	COG1607	acyl-coa hydrolase
K8Z39_RS21125	COG3689	TIGRFAM TIGR03943 family protein
K8Z39_RS21130	COG0701	Predicted permease
K8Z39_RS21145	COG0586	Pfam SNARE associated Golgi protein
K8Z39_RS21150	COG1051	belongs to the nudix hydrolase family
K8Z39_RS21155	COG5337	Spore coat protein CotH
K8Z39_RS21180	COG4166	transmembrane transport
K8Z39_RS21190	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z39_RS21200	COG0702	epimerase
K8Z39_RS21210	COG0803	Belongs to the bacterial solute-binding protein 9 family
K8Z39_RS21215	COG0456	acetyltransferase
K8Z39_RS21220	COG0523	cobalamin synthesis protein
K8Z39_RS21230	COG4989	oxidoreductase activity
K8Z39_RS21235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS21240	COG1231	oxidoreductase activity
K8Z39_RS21250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z39_RS21265	COG0783	Belongs to the Dps family
K8Z39_RS21270	COG3949	Membrane
K8Z39_RS21285	COG0840	transmembrane signaling receptor activity
K8Z39_RS21310	COG3152	Membrane
K8Z39_RS21315	COG2814	Major facilitator Superfamily
K8Z39_RS21320	COG0667	Aldo Keto reductase
K8Z39_RS21325	COG0640	Transcriptional regulator
K8Z39_RS21330	COG1404	Belongs to the peptidase S8 family
K8Z39_RS21335	COG2002	toxin-antitoxin pair type II binding
K8Z39_RS21340	COG0577	efflux transmembrane transporter activity
K8Z39_RS21375	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z39_RS21385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_RS21390	COG1279	arginine transmembrane transporter activity
K8Z39_RS21395	COG2814	Major facilitator Superfamily
K8Z39_RS21405	COG1082	Xylose isomerase domain protein TIM barrel
K8Z39_RS21415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z39_RS21440	COG1247	-acetyltransferase
K8Z39_RS21445	COG1285	pathogenesis
K8Z39_RS21460	COG5002	protein histidine kinase activity
K8Z39_RS21465	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS21480	COG1316	TRANSCRIPTIONal
K8Z39_RS21505	COG0460	homoserine dehydrogenase
K8Z39_RS21535	COG0300	oxidoreductase activity
K8Z39_RS21540	COG5002	protein histidine kinase activity
K8Z39_RS21545	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS21550	COG1132	(ABC) transporter
K8Z39_RS21560	COG0791	NLP P60 protein
K8Z39_RS21560	COG1388	LysM domain
K8Z39_RS21575	COG1686	Belongs to the peptidase S11 family
K8Z39_RS21615	COG1216	Glycosyl transferase, family 2
K8Z39_RS21625	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K8Z39_RS21630	COG4988	ABC transporter
K8Z39_RS21635	COG1294	oxidase, subunit
K8Z39_RS21640	COG1271	oxidase subunit
K8Z39_RS21680	COG0583	DNA-binding transcription factor activity
K8Z39_RS21700	COG0411	ABC transporter
K8Z39_RS21710	COG0523	cobalamin synthesis protein
K8Z39_RS21715	COG1231	oxidoreductase activity
K8Z39_RS21725	COG0628	permease
K8Z39_RS21735	COG0778	Nitroreductase
K8Z39_RS21740	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z39_RS21745	COG1959	2 iron, 2 sulfur cluster binding
K8Z39_RS21750	COG0583	DNA-binding transcription factor activity
K8Z39_RS21755	COG0697	spore germination
K8Z39_RS21765	COG4549	nuclear export factor GLE1
K8Z39_RS21770	COG1276	copper resistance
K8Z39_RS21770	COG2372	response to copper ion
K8Z39_RS21785	COG1114	Component of the transport system for branched-chain amino acids
K8Z39_RS21805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z39_RS21815	COG2132	Multicopper oxidase
K8Z39_RS21825	COG0006	proline dipeptidase activity
K8Z39_RS21835	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z39_RS21850	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K8Z39_RS21855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_RS21865	COG2390	Transcriptional regulator
K8Z39_RS21870	COG1309	transcriptional regulator
K8Z39_RS21905	COG0531	amino acid
K8Z39_RS21910	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z39_RS21925	COG1914	H( )-stimulated, divalent metal cation uptake system
K8Z39_RS21930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS21935	COG4166	transmembrane transport
K8Z39_RS21955	COG0427	acetyl-CoA hydrolase
K8Z39_RS21960	COG3279	Response regulator of the LytR AlgR family
K8Z39_RS21970	COG3384	dioxygenase
K8Z39_RS21975	COG2814	Major facilitator Superfamily
K8Z39_RS22000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K8Z39_RS22020	COG0028	Belongs to the TPP enzyme family
K8Z39_RS22025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z39_RS22035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z39_RS22055	COG2323	membrane
K8Z39_RS22060	COG5566	PFAM Mor transcription activator
K8Z39_RS22065	COG0733	neurotransmitter:sodium symporter activity
K8Z39_RS22085	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z39_RS22090	COG2223	nitrite transmembrane transporter activity
K8Z39_RS22095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z39_RS22105	COG0477	Major facilitator Superfamily
K8Z39_RS22115	COG1695	Transcriptional regulator
K8Z39_RS22165	COG3620	sequence-specific DNA binding
K8Z39_RS22180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z39_RS22185	COG0784	Response regulator, receiver
K8Z39_RS22190	COG4191	Histidine kinase
K8Z39_RS22195	COG0281	malic enzyme
K8Z39_RS22200	COG1027	Aspartate ammonia-lyase
K8Z39_RS22210	COG0528	UMP kinase activity
K8Z39_RS22215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z39_RS22235	COG1131	(ABC) transporter
K8Z39_RS22270	COG2733	membrane
K8Z39_RS22290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z39_RS22315	COG3340	Belongs to the peptidase S51 family
K8Z39_RS22320	COG0534	Mate efflux family protein
K8Z39_RS22350	COG0789	Transcriptional regulator
K8Z39_RS22355	COG1757	Na H antiporter
K8Z39_RS22370	COG0701	Predicted permease
K8Z39_RS22375	COG0523	cobalamin synthesis protein
K8Z39_RS22385	COG0697	spore germination
K8Z39_RS22390	COG1802	Transcriptional regulator
K8Z39_RS22420	COG0367	asparagine synthase
K8Z39_RS22450	COG0406	alpha-ribazole phosphatase activity
K8Z39_RS22455	COG1686	Belongs to the peptidase S11 family
K8Z39_RS22495	COG3842	ATPase activity
K8Z39_RS22500	COG0583	DNA-binding transcription factor activity
K8Z39_RS22525	COG2329	Antibiotic biosynthesis monooxygenase
K8Z39_RS22560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z39_RS22565	COG4786	Flagellar basal body rod
K8Z39_RS22570	COG1419	protein localization to endoplasmic reticulum
K8Z39_RS22575	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z39_RS22580	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z39_RS22590	COG1987	bacterial-type flagellum assembly
K8Z39_RS22595	COG1338	Plays a role in the flagellum-specific transport system
K8Z39_RS22605	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z39_RS22605	COG1776	CheC inhibitor of MCP methylation
K8Z39_RS22610	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z39_RS22620	COG0741	lytic transglycosylase activity
K8Z39_RS22625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z39_RS22640	COG0784	Response regulator, receiver
K8Z39_RS22640	COG0835	chemotaxis
K8Z39_RS22675	COG1157	protein secretion by the type III secretion system
K8Z39_RS22685	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z39_RS22690	COG1766	The M ring may be actively involved in energy transduction
K8Z39_RS22700	COG1558	bacterial-type flagellum-dependent cell motility
K8Z39_RS22705	COG1815	bacterial-type flagellum-dependent cell motility
K8Z39_RS22725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z39_RS22730	COG1256	bacterial-type flagellum assembly
K8Z39_RS22750	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z39_RS22765	COG1776	CheC inhibitor of MCP methylation
K8Z39_RS22765	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z39_RS22770	COG2198	Histidine kinase
K8Z39_RS22770	COG0643	Histidine kinase
K8Z39_RS22775	COG2201	protein-glutamate methylesterase activity
K8Z39_RS22780	COG1360	Flagellar Motor Protein
K8Z39_RS22785	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z39_RS22795	COG1923	regulation of RNA biosynthetic process
K8Z39_RS22835	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K8Z39_RS22840	COG2323	membrane
K8Z39_RS22850	COG4978	Transcriptional regulator
K8Z39_RS22850	COG0789	Transcriptional regulator
K8Z39_RS22855	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z39_RS22860	COG0475	glutathione-regulated potassium exporter activity
K8Z39_RS22870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z39_RS22875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z39_RS22895	COG1280	lysine exporter protein (LysE YggA)
K8Z39_RS22900	COG3403	YqcI/YcgG family
K8Z39_RS22935	COG0328	RNA-DNA hybrid ribonuclease activity
K8Z39_RS22955	COG0454	-acetyltransferase
K8Z39_RS22970	COG0438	transferase activity, transferring glycosyl groups
K8Z39_RS22975	COG1215	transferase activity, transferring glycosyl groups
K8Z39_RS22990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K8Z39_RS23000	COG3944	biosynthesis protein
K8Z39_RS23015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z39_RS23045	COG0456	acetyltransferase
K8Z39_RS23055	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z39_RS23065	COG2311	Membrane
K8Z39_RS23070	COG2233	PERMEase
K8Z39_RS23080	COG0024	Methionine aminopeptidase
K8Z39_RS23090	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K8Z39_RS23095	COG1199	ATP-dependent helicase activity
K8Z39_RS23105	COG0116	Belongs to the methyltransferase superfamily
K8Z39_RS23160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z39_RS23160	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z39_RS23170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K8Z39_RS23175	COG3935	DnaD domain protein
K8Z39_RS23195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K8Z39_RS23195	COG1199	ATP-dependent helicase activity
K8Z39_RS23230	COG0438	transferase activity, transferring glycosyl groups
K8Z39_RS23250	COG1694	Mazg nucleotide pyrophosphohydrolase
K8Z39_RS23255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_RS23265	COG2738	Putative neutral zinc metallopeptidase
K8Z39_RS23280	COG4347	Protein of unknown function (DUF1405)
K8Z39_RS23285	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z39_RS23285	COG2010	Cytochrome c
K8Z39_RS23290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z39_RS23310	COG0457	Tetratricopeptide repeat
K8Z39_RS23340	COG0142	geranyltranstransferase activity
K8Z39_RS23350	COG0142	geranyltranstransferase activity
K8Z39_RS23365	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z39_RS23435	COG0252	asparaginase activity
K8Z39_RS23440	COG0492	ferredoxin-NADP+ reductase activity
K8Z39_RS23460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K8Z39_RS23470	COG0789	Transcriptional regulator
K8Z39_RS23475	COG1408	metallophosphoesterase
K8Z39_RS23485	COG1266	CAAX protease self-immunity
K8Z39_RS23490	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z39_RS23500	COG1141	Ferredoxin
K8Z39_RS23505	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
K8Z39_RS23520	COG2096	Adenosyltransferase
K8Z39_RS23525	COG5002	protein histidine kinase activity
K8Z39_RS23530	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS23535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z39_RS23540	COG1333	cytochrome c biogenesis protein
K8Z39_RS23550	COG1187	pseudouridine synthase activity
K8Z39_RS23555	COG0700	Nucleoside recognition
K8Z39_RS23560	COG2715	membrane protein required for spore maturation
K8Z39_RS23565	COG1686	Belongs to the peptidase S11 family
K8Z39_RS23570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z39_RS23585	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K8Z39_RS23585	COG0392	lysyltransferase activity
K8Z39_RS23600	COG5002	protein histidine kinase activity
K8Z39_RS23605	COG0582	viral genome integration into host DNA
K8Z39_RS23615	COG1801	Protein of unknown function DUF72
K8Z39_RS23620	COG3852	Histidine kinase
K8Z39_RS23635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z39_RS23640	COG1392	Phosphate transport regulator
K8Z39_RS23645	COG0306	phosphate transporter
K8Z39_RS23650	COG0730	response to heat
K8Z39_RS23700	COG1114	Component of the transport system for branched-chain amino acids
K8Z39_RS23710	COG2197	response regulator
K8Z39_RS23715	COG4585	Histidine kinase
K8Z39_RS23720	COG4758	membrane
K8Z39_RS23735	COG1757	Na H antiporter
K8Z39_RS23760	COG0733	neurotransmitter:sodium symporter activity
K8Z39_RS23765	COG1648	precorrin-2 dehydrogenase activity
K8Z39_RS23785	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z39_RS23790	COG0529	Catalyzes the synthesis of activated sulfate
K8Z39_RS23810	COG0019	diaminopimelate decarboxylase activity
K8Z39_RS23820	COG1368	sulfuric ester hydrolase activity
K8Z39_RS23825	COG1183	phosphatidylcholine synthase activity
K8Z39_RS23840	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z39_RS23915	COG0440	acetolactate synthase activity
K8Z39_RS23920	COG0028	Belongs to the TPP enzyme family
K8Z39_RS23925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z39_RS23945	COG3874	Sporulation protein YtfJ
K8Z39_RS23950	COG4709	membrane
K8Z39_RS23955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z39_RS23960	COG1301	dicarboxylic acid transport
K8Z39_RS23970	COG1846	Transcriptional regulator
K8Z39_RS24020	COG0716	FMN binding
K8Z39_RS24045	COG1696	Membrane protein involved in D-alanine export
K8Z39_RS24055	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z39_RS24060	COG2070	2-Nitropropane dioxygenase
K8Z39_RS24065	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z39_RS24075	COG1335	isochorismatase
K8Z39_RS24085	COG1522	sequence-specific DNA binding
K8Z39_RS24105	COG1131	(ABC) transporter
K8Z39_RS24115	COG1131	(ABC) transporter
K8Z39_RS24120	COG1725	Transcriptional regulator
K8Z39_RS24135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z39_RS24140	COG1780	Probably involved in ribonucleotide reductase function
K8Z39_RS24170	COG4873	Protein conserved in bacteria
K8Z39_RS24185	COG0720	synthase
K8Z39_RS24195	COG5002	protein histidine kinase activity
K8Z39_RS24205	COG2318	DinB family
K8Z39_RS24215	COG1846	Transcriptional regulator
K8Z39_RS24220	COG3852	Histidine kinase
K8Z39_RS24230	COG2861	carbohydrate metabolic process
K8Z39_RS24240	COG0235	Class ii aldolase
K8Z39_RS24255	COG1349	DNA-binding transcription factor activity
K8Z39_RS24280	COG3842	ATPase activity
K8Z39_RS24285	COG1840	ABC-type Fe3 transport system, periplasmic component
K8Z39_RS24300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z39_RS24310	COG3243	poly(R)-hydroxyalkanoic acid synthase
K8Z39_RS24315	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS24335	COG2030	dehydratase
K8Z39_RS24345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z39_RS24350	COG0861	Integral membrane protein TerC family
K8Z39_RS24355	COG2116	formate transmembrane transporter activity
K8Z39_RS24365	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K8Z39_RS24385	COG2186	Transcriptional regulator
K8Z39_RS24390	COG5002	protein histidine kinase activity
K8Z39_RS24395	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS24405	COG3835	regulator
K8Z39_RS24410	COG0277	FAD linked oxidase domain protein
K8Z39_RS24415	COG0247	lactate metabolic process
K8Z39_RS24420	COG2340	Cysteine-rich secretory protein family
K8Z39_RS24430	COG0564	pseudouridine synthase activity
K8Z39_RS24440	COG2409	Drug exporters of the RND superfamily
K8Z39_RS24455	COG1177	transmembrane transport
K8Z39_RS24460	COG1176	ABC-type spermidine putrescine transport system, permease component I
K8Z39_RS24470	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_RS24505	COG0681	Belongs to the peptidase S26 family
K8Z39_RS24510	COG1686	Belongs to the peptidase S11 family
K8Z39_RS24520	COG2226	methyltransferase
K8Z39_RS24540	COG1668	transmembrane transport
K8Z39_RS24545	COG4152	abc transporter atp-binding protein
K8Z39_RS24590	COG1476	TRANSCRIPTIONal
K8Z39_RS24600	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z39_RS24620	COG2226	methyltransferase
K8Z39_RS24660	COG5634	Uncharacterized conserved protein (DUF2278)
K8Z39_RS24665	COG1620	l-lactate permease
K8Z39_RS24700	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z39_RS24700	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K8Z39_RS24710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z39_RS24735	COG2382	esterase
K8Z39_RS24745	COG2153	protein acetylation
K8Z39_RS24790	COG1091	dTDP-4-dehydrorhamnose reductase activity
K8Z39_RS24805	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K8Z39_RS24825	COG0457	Tetratricopeptide repeat
K8Z39_RS24825	COG0463	Glycosyl transferase, family 2
K8Z39_RS24845	COG1216	Glycosyl transferase, family 2
K8Z39_RS24850	COG0772	Belongs to the SEDS family
K8Z39_RS24865	COG0564	pseudouridine synthase activity
K8Z39_RS24875	COG2357	RelA SpoT domain protein
K8Z39_RS24885	COG4116	CYTH
K8Z39_RS24890	COG2346	COG2346, Truncated hemoglobins
K8Z39_RS24905	COG1164	Oligoendopeptidase f
K8Z39_RS24915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z39_RS24925	COG0861	Integral membrane protein TerC family
K8Z39_RS24940	COG4166	transmembrane transport
K8Z39_RS24945	COG0534	Mate efflux family protein
K8Z39_RS24950	COG4608	Belongs to the ABC transporter superfamily
K8Z39_RS24955	COG0444	Belongs to the ABC transporter superfamily
K8Z39_RS24960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z39_RS24965	COG0601	transmembrane transport
K8Z39_RS24970	COG4166	transmembrane transport
K8Z39_RS24980	COG0180	Tryptophanyl-tRNA synthetase
K8Z39_RS24990	COG5504	Zn-dependent protease
K8Z39_RS24995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z39_RS25000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z39_RS25015	COG2267	carboxylic ester hydrolase activity
K8Z39_RS25035	COG0561	phosphatase activity
K8Z39_RS25050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_RS25075	COG2996	Protein conserved in bacteria
K8Z39_RS25095	COG0004	ammonium transporteR
K8Z39_RS25100	COG3339	Conserved Protein
K8Z39_RS25125	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z39_RS25135	COG0753	catalase activity
K8Z39_RS25145	COG0367	asparagine synthase
K8Z39_RS25170	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z39_RS25230	COG0398	Pfam SNARE associated Golgi protein
K8Z39_RS25250	COG1278	Cold shock
K8Z39_RS25265	COG2224	Isocitrate lyase
K8Z39_RS25270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K8Z39_RS25280	COG3693	PFAM glycoside hydrolase, family 10
K8Z39_RS25285	COG0840	transmembrane signaling receptor activity
K8Z39_RS25290	COG0501	Belongs to the peptidase M48B family
K8Z39_RS25310	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS25315	COG2205	protein histidine kinase activity
K8Z39_RS25325	COG3708	Transcriptional regulator
K8Z39_RS25325	COG2207	Transcriptional regulator
K8Z39_RS25330	COG1595	DNA-templated transcription, initiation
K8Z39_RS25340	COG1078	dGTPase activity
K8Z39_RS25345	COG1408	metallophosphoesterase
K8Z39_RS25350	COG1073	alpha beta
K8Z39_RS25440	COG4208	sulfate ABC transporter
K8Z39_RS25450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
K8Z39_RS25460	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_RS25470	COG0095	Lipoate-protein ligase
K8Z39_RS25475	COG1234	tRNA 3'-trailer cleavage
K8Z39_RS25485	COG1609	Transcriptional regulator
K8Z39_RS25490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS25520	COG1511	domain protein
K8Z39_RS25520	COG1511	domain protein
K8Z39_RS25525	COG1309	transcriptional regulator
K8Z39_RS25540	COG1484	DNA-dependent DNA replication
K8Z39_RS25575	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z39_RS25590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z39_RS25595	COG2329	Antibiotic biosynthesis monooxygenase
K8Z39_RS25600	COG3428	Bacterial PH domain
K8Z39_RS25605	COG3402	PFAM membrane-flanked domain
K8Z39_RS25610	COG0697	spore germination
K8Z39_RS25645	COG3428	Bacterial PH domain
K8Z39_RS25650	COG3402	PFAM membrane-flanked domain
K8Z39_RS25660	COG1309	transcriptional regulator
K8Z39_RS25675	COG4473	ABC transporter
K8Z39_RS25680	COG1131	(ABC) transporter
K8Z39_RS25685	COG0537	adenosine 5'-monophosphoramidase activity
K8Z39_RS25690	COG4980	gas vesicle protein
K8Z39_RS25715	COG3973	AAA domain
K8Z39_RS25720	COG0772	Belongs to the SEDS family
K8Z39_RS25730	COG1595	DNA-templated transcription, initiation
K8Z39_RS25745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K8Z39_RS25755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K8Z39_RS25760	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z39_RS25765	COG3620	sequence-specific DNA binding
K8Z39_RS25775	COG2140	Oxalate decarboxylase
K8Z39_RS25795	COG2267	carboxylic ester hydrolase activity
K8Z39_RS25805	COG0457	Tetratricopeptide repeat
K8Z39_RS25810	COG0346	lactoylglutathione lyase activity
K8Z39_RS25815	COG0346	lactoylglutathione lyase activity
K8Z39_RS25830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z39_RS25840	COG4717	serine-type aminopeptidase activity
K8Z39_RS25845	COG0420	3'-5' exonuclease activity
K8Z39_RS25865	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8Z39_RS25875	COG2186	Transcriptional regulator
K8Z39_RS25880	COG2807	transmembrane transport
K8Z39_RS25920	COG5002	protein histidine kinase activity
K8Z39_RS25920	COG2205	protein histidine kinase activity
K8Z39_RS25920	COG0784	Response regulator, receiver
K8Z39_RS25925	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z39_RS25930	COG2208	phosphoserine phosphatase activity
K8Z39_RS25940	COG1191	sigma factor activity
K8Z39_RS26020	COG2373	Large extracellular alpha-helical protein
K8Z39_RS26050	COG2376	Dihydroxyacetone kinase
K8Z39_RS26060	COG2376	Dihydroxyacetone kinase
K8Z39_RS26085	COG0640	Transcriptional regulator
K8Z39_RS26090	COG2814	Major facilitator Superfamily
K8Z39_RS26105	COG1183	phosphatidylcholine synthase activity
K8Z39_RS26155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z39_RS26170	COG1522	sequence-specific DNA binding
K8Z39_RS26175	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K8Z39_RS26200	COG0577	efflux transmembrane transporter activity
K8Z39_RS26240	COG2801	Transposase and inactivated derivatives
K8Z39_RS26250	COG1073	alpha beta
K8Z39_RS26280	COG2020	methyltransferase activity
K8Z39_RS26330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_RS26350	COG0477	Major facilitator Superfamily
K8Z39_RS26365	COG1842	Phage shock protein A
K8Z39_RS26375	COG1288	antiporter activity
K8Z39_RS26380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K8Z39_RS26425	COG0305	Participates in initiation and elongation during chromosome replication
K8Z39_RS26440	COG0494	nUDIX hydrolase
K8Z39_RS26445	COG3181	Tripartite tricarboxylate transporter family receptor
K8Z39_RS26450	COG4565	transcriptional regulatory protein
K8Z39_RS26455	COG3290	protein histidine kinase activity
K8Z39_RS26460	COG0477	Major facilitator Superfamily
K8Z39_RS26565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_RS26585	COG4608	Belongs to the ABC transporter superfamily
K8Z39_RS26590	COG0444	Belongs to the ABC transporter superfamily
K8Z39_RS26595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z39_RS26600	COG0601	transmembrane transport
K8Z39_RS26640	COG1363	Peptidase, m42
K8Z39_RS26660	COG1024	Enoyl-CoA hydratase
K8Z39_RS26680	COG2244	polysaccharide biosynthetic process
K8Z39_RS26685	COG0659	secondary active sulfate transmembrane transporter activity
K8Z39_RS26700	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_RS26705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z39_RS26710	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_RS26710	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS26720	COG0561	phosphatase activity
K8Z39_RS26735	COG3527	Alpha-acetolactate decarboxylase
K8Z39_RS26740	COG0028	Belongs to the TPP enzyme family
K8Z39_RS26770	COG0189	ligase activity
K8Z39_RS26785	COG1126	abc transporter atp-binding protein
K8Z39_RS26790	COG0765	amino acid transport
K8Z39_RS26795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z39_RS26800	COG1132	(ABC) transporter
K8Z39_RS26805	COG1132	(ABC) transporter
K8Z39_RS26810	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_RS26825	COG0531	amino acid
K8Z39_RS26835	COG0753	catalase activity
K8Z39_RS26840	COG0693	protein deglycase activity
K8Z39_RS26855	COG2211	Major facilitator Superfamily
K8Z39_RS26860	COG4533	DNA binding
K8Z39_RS26875	COG1733	regulation of RNA biosynthetic process
K8Z39_RS26880	COG2814	Major facilitator Superfamily
K8Z39_RS26885	COG1309	transcriptional regulator
K8Z39_RS26905	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS26910	COG0165	Argininosuccinate lyase
K8Z39_RS26910	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K8Z39_RS26915	COG1522	sequence-specific DNA binding
K8Z39_RS26935	COG2259	Doxx family
K8Z39_RS26945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z39_RS26945	COG1263	PTS System
K8Z39_RS26955	COG1737	Transcriptional regulator
K8Z39_RS26965	COG0475	glutathione-regulated potassium exporter activity
K8Z39_RS26970	COG0531	amino acid
K8Z39_RS27005	COG0586	Pfam SNARE associated Golgi protein
K8Z39_RS27040	COG3546	catalase activity
K8Z39_RS27045	COG1114	Component of the transport system for branched-chain amino acids
K8Z39_RS27060	COG5522	Integral membrane protein (intg_mem_TP0381)
K8Z39_RS27070	COG1136	(ABC) transporter
K8Z39_RS27075	COG0577	efflux transmembrane transporter activity
K8Z39_RS27080	COG3584	3D domain protein
K8Z39_RS27080	COG1388	LysM domain
K8Z39_RS27105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z39_RS27110	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z39_RS27115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z39_RS27115	COG3711	transcriptional antiterminator
K8Z39_RS27130	COG1283	sodium-dependent phosphate transmembrane transporter activity
K8Z39_RS27135	COG0604	alcohol dehydrogenase
K8Z39_RS27140	COG1316	TRANSCRIPTIONal
K8Z39_RS27150	COG0730	response to heat
K8Z39_RS27155	COG2210	Belongs to the sulfur carrier protein TusA family
K8Z39_RS27170	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z39_RS27175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z39_RS27175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_RS27180	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z39_RS27180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z39_RS27185	COG1937	Protein conserved in bacteria
K8Z39_RS27190	COG0446	pyridine nucleotide-disulphide oxidoreductase
K8Z39_RS27200	COG3591	Belongs to the peptidase S1B family
K8Z39_RS27210	COG2719	SpoVR family
K8Z39_RS27215	COG0778	Nitroreductase
K8Z39_RS27275	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS27280	COG2252	PERMEase
K8Z39_RS27290	COG1136	(ABC) transporter
K8Z39_RS27315	COG1846	Transcriptional regulator
K8Z39_RS27320	COG2814	Major facilitator Superfamily
K8Z39_RS27325	COG2205	protein histidine kinase activity
K8Z39_RS27365	COG0351	phosphomethylpyrimidine kinase
K8Z39_RS27370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z39_RS27380	COG2104	thiamine diphosphate biosynthetic process
K8Z39_RS27385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z39_RS27390	COG0352	thiamine-phosphate diphosphorylase activity
K8Z39_RS27395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z39_RS27400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z39_RS27405	COG1116	anion transmembrane transporter activity
K8Z39_RS27410	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z39_RS27430	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
K8Z39_RS27550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z39_RS27555	COG0581	inorganic phosphate transmembrane transporter activity
K8Z39_RS27560	COG0573	inorganic phosphate transmembrane transporter activity
K8Z39_RS27565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z39_RS27570	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z39_RS27570	COG1918	ferrous iron import across plasma membrane
K8Z39_RS27575	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z39_RS27580	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z39_RS27595	COG0531	amino acid
K8Z39_RS27600	COG0697	spore germination
K8Z39_RS27605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z39_RS27620	COG4990	cell redox homeostasis
K8Z39_RS27625	COG0833	amino acid
K8Z39_RS27635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K8Z39_RS27640	COG1845	cytochrome c oxidase, subunit III
K8Z39_RS27650	COG0475	glutathione-regulated potassium exporter activity
K8Z39_RS27650	COG0569	domain protein
K8Z39_RS27660	COG2153	protein acetylation
K8Z39_RS27675	COG2252	PERMEase
K8Z39_RS27680	COG1113	amino acid transport
K8Z39_RS27695	COG1114	Component of the transport system for branched-chain amino acids
K8Z39_RS27700	COG3104	oligopeptide transport
K8Z39_RS27720	COG1476	TRANSCRIPTIONal
K8Z39_RS27725	COG3583	domain protein
K8Z39_RS27725	COG3584	3D domain protein
K8Z39_RS27730	COG0840	transmembrane signaling receptor activity
K8Z39_RS27785	COG1063	alcohol dehydrogenase
K8Z39_RS27815	COG1879	ABC-type sugar transport system periplasmic component
K8Z39_RS27820	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z39_RS27835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K8Z39_RS27840	COG1609	Transcriptional regulator
K8Z39_RS27845	COG0477	Major facilitator Superfamily
K8Z39_RS27850	COG1846	Transcriptional regulator
K8Z39_RS27895	COG5002	protein histidine kinase activity
K8Z39_RS27900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K8Z39_RS27905	COG2378	regulation of single-species biofilm formation
K8Z39_RS27915	COG1595	DNA-templated transcription, initiation
K8Z39_RS27930	COG0833	amino acid
K8Z39_RS27935	COG0765	amino acid transport
K8Z39_RS27940	COG0765	amino acid transport
K8Z39_RS27945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z39_RS27950	COG1126	abc transporter atp-binding protein
K8Z39_RS27955	COG1115	amino acid carrier protein
K8Z39_RS27960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z39_RS27965	COG0697	spore germination
K8Z39_RS27980	COG0366	Alpha amylase catalytic
K8Z39_RS27985	COG1263	PTS System
K8Z39_RS27985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z39_RS27990	COG2188	Transcriptional regulator
K8Z39_RS27995	COG0531	amino acid
K8Z39_RS28015	COG0714	Associated with various cellular activities
K8Z39_RS28020	COG4548	von Willebrand factor, type A
K8Z39_RS28030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z39_RS28040	COG2226	methyltransferase
K8Z39_RS28050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_RS28055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_RS28060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_RS28065	COG3104	oligopeptide transport
K8Z39_RS28080	COG1620	l-lactate permease
K8Z39_RS28085	COG1027	Aspartate ammonia-lyase
K8Z39_RS28090	COG1253	flavin adenine dinucleotide binding
K8Z39_RS28095	COG0346	lactoylglutathione lyase activity
K8Z39_RS28100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_RS28105	COG1316	TRANSCRIPTIONal
K8Z39_RS28110	COG2720	vancomycin resistance protein
K8Z39_RS28130	COG3227	Zinc metalloprotease (Elastase)
K8Z39_RS28145	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K8Z39_RS28150	COG2217	Heavy metal translocating P-type atpase
K8Z39_RS28155	COG0640	Transcriptional regulator
K8Z39_RS28180	COG2427	Protein of unknown function (DUF1641)
K8Z39_RS28185	COG3383	formate dehydrogenase (NAD+) activity
K8Z39_RS28190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z39_RS28195	COG0456	acetyltransferase
K8Z39_RS28195	COG0454	-acetyltransferase
K8Z39_RS28205	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS28210	COG5002	protein histidine kinase activity
K8Z39_RS28220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_RS28225	COG0697	spore germination
K8Z39_RS28235	COG0281	malic enzyme
K8Z39_RS28240	COG3493	citrate carrier protein
K8Z39_RS28245	COG4565	transcriptional regulatory protein
K8Z39_RS28250	COG3290	protein histidine kinase activity
K8Z39_RS28260	COG4990	cell redox homeostasis
K8Z39_RS28270	COG5002	protein histidine kinase activity
K8Z39_RS28270	COG3850	Histidine kinase
K8Z39_RS28275	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS28280	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K8Z39_RS28290	COG0395	ABC-type sugar transport system, permease component
K8Z39_RS28295	COG1175	transmembrane transport
K8Z39_RS28300	COG3842	ATPase activity
K8Z39_RS28305	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z39_RS28330	COG2851	Citrate transporter
K8Z39_RS28335	COG4565	transcriptional regulatory protein
K8Z39_RS28340	COG3290	protein histidine kinase activity
K8Z39_RS28350	COG2268	Band 7 protein
K8Z39_RS28355	COG1585	Membrane protein implicated in regulation of membrane protease activity
K8Z39_RS28365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z39_RS28385	COG2766	serine protein kinase
K8Z39_RS28390	COG1716	ATPase activity
K8Z39_RS28390	COG5001	Diguanylate cyclase
K8Z39_RS28395	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K8Z39_RS28420	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K8Z39_RS28485	COG0582	viral genome integration into host DNA
K8Z39_RS28510	COG4974	Belongs to the 'phage' integrase family
K8Z39_RS28615	COG0735	belongs to the Fur family
K8Z39_RS28620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K8Z39_RS28640	COG4555	ABC transporter
K8Z39_RS28655	COG0069	glutamate synthase activity
K8Z39_RS28655	COG0070	glutamate synthase
K8Z39_RS28655	COG0067	glutamate synthase
K8Z39_RS28660	COG4129	membrane
K8Z39_RS28665	COG1132	(ABC) transporter
K8Z39_RS28690	COG1194	a g-specific adenine glycosylase
K8Z39_RS28695	COG1988	membrane-bound metal-dependent
K8Z39_RS28725	COG1090	epimerase
K8Z39_RS28730	COG1228	amidohydrolase
K8Z39_RS28750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K8Z39_RS28770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z39_RS28770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K8Z39_RS28780	COG0463	Glycosyl transferase, family 2
K8Z39_RS28795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z39_RS28800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z39_RS28800	COG1263	PTS System
K8Z39_RS28830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z39_RS28835	COG0833	amino acid
K8Z39_RS28845	COG3829	transcription factor binding
K8Z39_RS28860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K8Z39_RS28865	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z39_RS28885	COG0535	radical SAM domain protein
K8Z39_RS28895	COG0387	Pfam Sodium calcium exchanger
K8Z39_RS28900	COG3871	stress protein (general stress protein 26)
K8Z39_RS28915	COG0586	Pfam SNARE associated Golgi protein
K8Z39_RS28935	COG0697	spore germination
K8Z39_RS28940	COG2217	Heavy metal translocating P-type atpase
K8Z39_RS28945	COG1295	ribonuclease BN
K8Z39_RS28955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K8Z39_RS28970	COG3853	Toxic anion resistance protein (TelA)
K8Z39_RS28980	COG0861	Integral membrane protein TerC family
K8Z39_RS28985	COG2310	stress, protein
K8Z39_RS28990	COG2310	stress, protein
K8Z39_RS28995	COG2310	stress, protein
K8Z39_RS29025	COG2270	Major facilitator Superfamily
K8Z39_RS29075	COG1116	anion transmembrane transporter activity
K8Z39_RS29085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z39_RS29105	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K8Z39_RS29135	COG1263	PTS System
K8Z39_RS29135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z39_RS29135	COG2190	(PTS) system
K8Z39_RS29140	COG0366	Alpha amylase catalytic
K8Z39_RS29155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z39_RS29160	COG0549	Belongs to the carbamate kinase family
K8Z39_RS29185	COG0840	transmembrane signaling receptor activity
K8Z39_RS29195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z39_RS29200	COG0765	amino acid transport
K8Z39_RS29210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z39_RS29210	COG0723	plastoquinol--plastocyanin reductase activity
K8Z39_RS29215	COG2814	Major facilitator Superfamily
K8Z39_RS29220	COG3541	Predicted nucleotidyltransferase
K8Z39_RS29240	COG5002	protein histidine kinase activity
K8Z39_RS29265	COG0166	Belongs to the GPI family
K8Z39_RS29275	COG0492	ferredoxin-NADP+ reductase activity
K8Z39_RS29280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_RS29285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_RS29290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_RS29310	COG0450	alkyl hydroperoxide reductase
K8Z39_RS29325	COG1473	amidohydrolase
K8Z39_RS29355	COG4807	Protein conserved in bacteria
K8Z39_RS29360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z39_RS29370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_RS29390	COG2309	aminopeptidase activity
K8Z39_RS29400	COG2076	Multidrug Resistance protein
K8Z39_RS29405	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_RS29415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K8Z39_RS29425	COG1597	lipid kinase activity
K8Z39_RS29445	COG4682	membrane
K8Z39_RS29450	COG1846	Transcriptional regulator
K8Z39_RS29455	COG0003	Pfam Anion-transporting ATPase
K8Z39_RS29470	COG1464	Belongs to the NlpA lipoprotein family
K8Z39_RS29475	COG2011	ABC-type metal ion transport system permease component
K8Z39_RS29485	COG1335	isochorismatase
K8Z39_RS29500	COG4851	CamS sex pheromone cAM373 precursor
K8Z39_RS29510	COG0210	DNA helicase
K8Z39_RS29535	COG0151	Belongs to the GarS family
K8Z39_RS29545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K8Z39_RS29555	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K8Z39_RS29570	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K8Z39_RS29580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K8Z39_RS29585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K8Z39_RS29590	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K8Z39_RS29625	COG0697	spore germination
K8Z39_RS29645	COG0463	Glycosyl transferase, family 2
K8Z39_RS29645	COG1216	Glycosyl transferase, family 2
K8Z39_RS29655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z39_RS29695	COG0745	RESPONSE REGULATOR receiver
K8Z39_RS29700	COG2205	protein histidine kinase activity
K8Z39_RS29740	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z39_RS29765	COG5002	protein histidine kinase activity
K8Z39_RS29775	COG2252	PERMEase
K8Z39_RS29795	COG4824	toxin secretion phage lysis holin
K8Z39_RS29885	COG3728	DNA packaging
K8Z39_RS29885	COG5484	DNA packaging
K8Z39_RS29935	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K8Z39_RS29940	COG1687	branched-chain amino acid
K8Z39_RS29965	COG2233	PERMEase
K8Z39_RS29970	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
K8Z39_RS29975	COG0288	reversible hydration of carbon dioxide
K8Z39_RS29980	COG1522	sequence-specific DNA binding
K8Z39_RS30010	COG0542	response to heat
K8Z39_RS30015	COG0494	nUDIX hydrolase
K8Z39_RS30020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K8Z39_RS30035	COG0457	Tetratricopeptide repeat
K8Z39_RS30175	COG3344	reverse transcriptase
K8Z39_RS30190	COG3344	reverse transcriptase
K8Z39_RS30375	COG3344	reverse transcriptase
K8Z39_RS30395	COG2814	Major facilitator Superfamily
K8Z39_RS30430	COG3344	reverse transcriptase
K8Z39_RS30450	COG3344	reverse transcriptase
K8Z39_RS30510	COG2311	Membrane
K8Z39_RS30575	COG2801	Transposase and inactivated derivatives
K8Z39_RS30580	COG0457	Tetratricopeptide repeat
K8Z39_RS30600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z39_RS30630	COG2002	toxin-antitoxin pair type II binding
K8Z39_RS30635	COG4166	transmembrane transport
K8Z39_RS30655	COG4974	Belongs to the 'phage' integrase family
K8Z39_RS30725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K8Z39_RS30740	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z39_RS30755	COG4824	toxin secretion phage lysis holin
K8Z39_RS30780	COG5444	nuclease activity
K8Z39_RS30825	COG4974	Belongs to the 'phage' integrase family
K8Z39_RS30855	COG1073	alpha beta
K8Z39_RS30870	COG3104	oligopeptide transport
K8Z39_RS30905	COG0457	Tetratricopeptide repeat
K8Z39_RS30925	COG4974	Belongs to the 'phage' integrase family
K8Z39_RS31005	COG1132	(ABC) transporter
K8Z39_RS31010	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z39_RS31020	COG1131	(ABC) transporter
K8Z39_RS31040	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K8Z39_RS31080	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_RS31080	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS31090	COG3227	Zinc metalloprotease (Elastase)
K8Z39_RS31100	COG1132	(ABC) transporter
K8Z39_RS31110	COG3011	Protein conserved in bacteria
K8Z39_RS31125	COG0457	Tetratricopeptide repeat
K8Z39_RS31160	COG1132	(ABC) transporter
K8Z39_RS31180	COG1475	DNA binding
K8Z39_RS31235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z39_RS31240	COG3321	synthase
K8Z39_RS31240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z39_RS31240	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_RS31240	COG0300	oxidoreductase activity
K8Z39_RS31240	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS31255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z39_RS31260	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z39_RS31275	COG1960	acyl-CoA dehydrogenase activity
K8Z39_RS31295	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS31295	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_RS31295	COG0300	oxidoreductase activity
K8Z39_RS31295	COG3321	synthase
K8Z39_RS31295	COG3321	synthase
K8Z39_RS31295	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_RS31295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z39_RS31295	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_RS31295	COG0300	oxidoreductase activity
K8Z39_RS31295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z39_RS31350	COG0667	Aldo Keto reductase
K8Z39_RS31375	COG1396	sequence-specific DNA binding
K8Z39_RS31390	COG1216	Glycosyl transferase, family 2
K8Z39_RS31395	COG1024	Enoyl-CoA hydratase
K8Z39_RS31415	COG1484	DNA-dependent DNA replication
K8Z39_RS31585	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS31605	COG0739	heme binding
K8Z39_RS31610	COG0741	lytic transglycosylase activity
K8Z39_RS31640	COG1361	Conserved repeat domain
K8Z39_RS31645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_RS31670	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z39_RS31690	COG4974	Belongs to the 'phage' integrase family
K8Z39_RS31705	COG0457	Tetratricopeptide repeat
K8Z39_RS31725	COG3344	reverse transcriptase
K8Z39_RS31810	COG1136	(ABC) transporter
K8Z39_RS32065	COG0592	DNA-directed DNA polymerase activity
K8Z39_RS32070	COG4712	double-strand break repair protein
K8Z39_RS32105	COG3344	reverse transcriptase
K8Z39_RS32115	COG3344	reverse transcriptase
K8Z39_RS32345	COG3344	reverse transcriptase
K8Z39_RS32390	COG2311	Membrane
K8Z39_RS32410	COG0457	Tetratricopeptide repeat
K8Z39_RS32435	COG0583	DNA-binding transcription factor activity
K8Z39_RS32440	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z39_RS32485	COG0730	response to heat
K8Z39_RS32510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z39_RS32535	COG2002	toxin-antitoxin pair type II binding
K8Z39_RS32540	COG4166	transmembrane transport
K8Z39_RS32560	COG4974	Belongs to the 'phage' integrase family
K8Z39_RS32590	COG0583	DNA-binding transcription factor activity
K8Z39_RS32595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_RS32600	COG0402	S-adenosylhomocysteine deaminase activity
K8Z39_RS32675	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z39_RS32695	COG4824	toxin secretion phage lysis holin
K8Z39_RS32735	COG0840	transmembrane signaling receptor activity
K8Z39_RS32780	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS32780	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_RS32785	COG0475	glutathione-regulated potassium exporter activity
K8Z39_RS32790	COG0490	domain, Protein
K8Z39_RS32800	COG0840	transmembrane signaling receptor activity
K8Z39_RS32855	COG0583	DNA-binding transcription factor activity
K8Z39_RS32895	COG0640	Transcriptional regulator
K8Z39_RS32935	COG0675	Transposase, IS605 OrfB family
K8Z39_RS32950	COG2828	Protein conserved in bacteria
K8Z39_RS33025	COG0741	lytic transglycosylase activity
K8Z39_RS33025	COG0791	NLP P60 protein
K8Z39_RS33275	COG0457	Tetratricopeptide repeat
K8Z39_RS33320	COG0739	heme binding
K8Z39_RS33495	COG3344	reverse transcriptase
K8Z39_RS33635	COG3344	reverse transcriptase
K8Z39_RS33725	COG0551	DNA topoisomerase type I activity
K8Z39_RS33725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z39_RS33775	COG0457	Tetratricopeptide repeat
K8Z39_RS33780	COG4166	transmembrane transport
K8Z39_RS33810	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
K8Z39_RS33850	COG0791	NLP P60 protein
K8Z39_RS33850	COG0741	lytic transglycosylase activity
K8Z39_RS34055	COG1923	regulation of RNA biosynthetic process
K8Z39_RS34065	COG0457	Tetratricopeptide repeat
K8Z39_RS34305	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_RS34305	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS34390	COG1073	alpha beta
K8Z39_RS34400	COG2197	response regulator
K8Z39_RS34405	COG1476	TRANSCRIPTIONal
K8Z39_RS34470	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z39_RS34610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z39_RS34680	COG3331	DNA recombination
K8Z39_RS34800	COG1396	sequence-specific DNA binding
K8Z39_RS34855	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_RS34855	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_RS34855	COG1388	LysM domain
K8Z39_RS34990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K8Z39_RS35185	COG0457	Tetratricopeptide repeat
K8Z39_RS35295	COG3344	reverse transcriptase
K8Z39_RS35300	COG3654	unkown
K8Z39_RS35310	COG0582	viral genome integration into host DNA
K8Z39_RS35360	COG0457	Tetratricopeptide repeat
K8Z39_RS35380	COG0501	Belongs to the peptidase M48B family