locus-tag	class	description
FBF59_RS00005	COG1196	nuclear chromosome segregation
FBF59_RS00010	COG0552	protein localization to endoplasmic reticulum
FBF59_RS00020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FBF59_RS00030	COG1837	Belongs to the UPF0109 family
FBF59_RS00070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FBF59_RS00075	COG0758	DNA mediated transformation
FBF59_RS00080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FBF59_RS00090	COG4974	Belongs to the 'phage' integrase family
FBF59_RS00135	COG4589	Belongs to the CDS family
FBF59_RS00145	COG0750	zinc metalloprotease
FBF59_RS00165	COG0195	Participates in both transcription termination and antitermination
FBF59_RS00170	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FBF59_RS00175	COG1358	cellular component organization or biogenesis
FBF59_RS00185	COG1550	Protein conserved in bacteria
FBF59_RS00190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FBF59_RS00200	COG0196	riboflavin kinase activity
FBF59_RS00215	COG0726	polysaccharide deacetylase
FBF59_RS00220	COG0612	Peptidase, M16
FBF59_RS00225	COG1873	PFAM PRC-barrel domain
FBF59_RS00230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FBF59_RS00255	COG1396	sequence-specific DNA binding
FBF59_RS00300	COG0305	Participates in initiation and elongation during chromosome replication
FBF59_RS00330	COG0582	viral genome integration into host DNA
FBF59_RS00335	COG1278	Cold shock
FBF59_RS00345	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FBF59_RS00465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FBF59_RS00470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FBF59_RS00475	COG0527	aspartate kinase activity
FBF59_RS00485	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FBF59_RS00490	COG0740	serine-type endopeptidase activity
FBF59_RS00510	COG2188	Transcriptional regulator
FBF59_RS00515	COG1744	ABC transporter substrate-binding protein PnrA-like
FBF59_RS00520	COG3845	ABC transporter
FBF59_RS00525	COG4603	Belongs to the binding-protein-dependent transport system permease family
FBF59_RS00530	COG1079	Belongs to the binding-protein-dependent transport system permease family
FBF59_RS00535	COG0612	Peptidase, M16
FBF59_RS00540	COG0612	Peptidase, M16
FBF59_RS00545	COG0300	oxidoreductase activity
FBF59_RS00560	COG1426	Protein conserved in bacteria
FBF59_RS00565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FBF59_RS00585	COG1692	metallophosphoesterase
FBF59_RS00590	COG2359	stage V sporulation protein S
FBF59_RS00600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FBF59_RS00600	COG0674	pyruvate-flavodoxin oxidoreductase activity
FBF59_RS00605	COG1013	pyruvate-flavodoxin oxidoreductase activity
FBF59_RS00615	COG4550	Control of competence regulator ComK, YlbF/YmcA
FBF59_RS00640	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FBF59_RS00645	COG1368	sulfuric ester hydrolase activity
FBF59_RS00660	COG3773	Cell wall hydrolase
FBF59_RS00665	COG1404	Belongs to the peptidase S8 family
FBF59_RS00675	COG0840	transmembrane signaling receptor activity
FBF59_RS00690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FBF59_RS00700	COG1346	cytolysis
FBF59_RS00740	COG3300	MHYT domain
FBF59_RS00740	COG5001	Diguanylate cyclase
FBF59_RS00745	COG2267	carboxylic ester hydrolase activity
FBF59_RS00760	COG2364	Membrane
FBF59_RS00770	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FBF59_RS00775	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FBF59_RS00780	COG2169	Transcriptional regulator
FBF59_RS00785	COG0708	Exodeoxyribonuclease III
FBF59_RS00790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FBF59_RS00795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FBF59_RS00800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FBF59_RS00805	COG1120	ATPase activity
FBF59_RS00810	COG2819	hydrolase of the alpha beta superfamily
FBF59_RS00830	COG1937	Protein conserved in bacteria
FBF59_RS00835	COG2608	mercury ion transmembrane transporter activity
FBF59_RS00840	COG2217	Heavy metal translocating P-type atpase
FBF59_RS00855	COG2116	formate transmembrane transporter activity
FBF59_RS00860	COG1408	metallophosphoesterase
FBF59_RS00880	COG1113	amino acid transport
FBF59_RS00890	COG2322	membrane
FBF59_RS00895	COG1979	alcohol dehydrogenase
FBF59_RS00900	COG1349	DNA-binding transcription factor activity
FBF59_RS00905	COG1105	Belongs to the carbohydrate kinase PfkB family
FBF59_RS00910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FBF59_RS00910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FBF59_RS00910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FBF59_RS00915	COG3584	3D domain protein
FBF59_RS00915	COG1388	LysM domain
FBF59_RS00945	COG0464	growth
FBF59_RS00950	COG2860	membrane
FBF59_RS00955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FBF59_RS00960	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FBF59_RS00965	COG0789	Transcriptional regulator
FBF59_RS00970	COG0174	glutamine synthetase
FBF59_RS00975	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FBF59_RS01005	COG0741	lytic transglycosylase activity
FBF59_RS01010	COG0741	lytic transglycosylase activity
FBF59_RS01010	COG0739	heme binding
FBF59_RS01010	COG1196	nuclear chromosome segregation
FBF59_RS01020	COG1695	Transcriptional regulator
FBF59_RS01040	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FBF59_RS01050	COG0737	Belongs to the 5'-nucleotidase family
FBF59_RS01055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FBF59_RS01090	COG1132	(ABC) transporter
FBF59_RS01095	COG1132	(ABC) transporter
FBF59_RS01120	COG0730	response to heat
FBF59_RS01135	COG1346	cytolysis
FBF59_RS01145	COG0583	DNA-binding transcription factor activity
FBF59_RS01165	COG1131	(ABC) transporter
FBF59_RS01175	COG1473	amidohydrolase
FBF59_RS01190	COG0785	Cytochrome C biogenesis protein
FBF59_RS01195	COG4846	Membrane protein involved in cytochrome C biogenesis
FBF59_RS01250	COG0010	Belongs to the arginase family
FBF59_RS01255	COG1329	Transcriptional regulator
FBF59_RS01260	COG1902	pentaerythritol trinitrate reductase activity
FBF59_RS01265	COG0069	glutamate synthase activity
FBF59_RS01275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FBF59_RS01280	COG0346	lactoylglutathione lyase activity
FBF59_RS01285	COG0400	carboxylic ester hydrolase activity
FBF59_RS01290	COG5002	protein histidine kinase activity
FBF59_RS01305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FBF59_RS01340	COG1396	sequence-specific DNA binding
FBF59_RS01345	COG0318	PFAM AMP-dependent synthetase and ligase
FBF59_RS01350	COG1268	BioY protein
FBF59_RS01355	COG0318	PFAM AMP-dependent synthetase and ligase
FBF59_RS01360	COG0183	Belongs to the thiolase family
FBF59_RS01375	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FBF59_RS01385	COG2211	Major facilitator Superfamily
FBF59_RS01415	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FBF59_RS01420	COG1122	ATPase activity
FBF59_RS01430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FBF59_RS01455	COG0824	Thioesterase
FBF59_RS01460	COG4841	protein insertion into membrane
FBF59_RS01480	COG0745	RESPONSE REGULATOR receiver
FBF59_RS01485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FBF59_RS01490	COG1832	CoA-binding protein
FBF59_RS01495	COG0187	DNA topoisomerase II activity
FBF59_RS01500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FBF59_RS01505	COG0673	inositol 2-dehydrogenase activity
FBF59_RS01525	COG1131	(ABC) transporter
FBF59_RS01535	COG1595	DNA-templated transcription, initiation
FBF59_RS01545	COG1316	TRANSCRIPTIONal
FBF59_RS01550	COG1301	dicarboxylic acid transport
FBF59_RS01555	COG4166	transmembrane transport
FBF59_RS01565	COG4166	transmembrane transport
FBF59_RS01570	COG4166	transmembrane transport
FBF59_RS01575	COG2226	methyltransferase
FBF59_RS01625	COG3383	formate dehydrogenase (NAD+) activity
FBF59_RS01675	COG5377	YqaJ viral recombinase family
FBF59_RS01680	COG3723	Recombinational DNA repair protein, rece pathway
FBF59_RS01690	COG1484	DNA-dependent DNA replication
FBF59_RS01730	COG3617	BRO family, N-terminal domain
FBF59_RS01755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FBF59_RS01855	COG1388	LysM domain
FBF59_RS01855	COG3409	Peptidoglycan-binding domain 1 protein
FBF59_RS01855	COG5632	N-Acetylmuramoyl-L-alanine amidase
FBF59_RS01900	COG2427	Protein of unknown function (DUF1641)
FBF59_RS01905	COG5609	conserved protein (DUF2294)
FBF59_RS01910	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FBF59_RS01920	COG2116	formate transmembrane transporter activity
FBF59_RS01925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FBF59_RS01930	COG0303	'Molybdopterin
FBF59_RS01935	COG0314	molybdopterin synthase activity
FBF59_RS01945	COG0489	protein tyrosine kinase activity
FBF59_RS01960	COG3326	Membrane
FBF59_RS01965	COG2962	Rard protein
FBF59_RS01970	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FBF59_RS01975	COG1657	PFAM Prenyltransferase squalene oxidase
FBF59_RS01985	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS01990	COG1012	belongs to the aldehyde dehydrogenase family
FBF59_RS02000	COG4145	pantothenate transmembrane transporter activity
FBF59_RS02015	COG0165	Argininosuccinate lyase
FBF59_RS02025	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS02045	COG1051	belongs to the nudix hydrolase family
FBF59_RS02055	COG0716	FMN binding
FBF59_RS02090	COG2720	vancomycin resistance protein
FBF59_RS02095	COG2514	catechol 2,3-dioxygenase activity
FBF59_RS02105	COG1285	pathogenesis
FBF59_RS02115	COG3852	Histidine kinase
FBF59_RS02140	COG1876	peptidase activity
FBF59_RS02175	COG1396	sequence-specific DNA binding
FBF59_RS02275	COG0582	viral genome integration into host DNA
FBF59_RS02320	COG1802	Transcriptional regulator
FBF59_RS02320	COG4626	Terminase
FBF59_RS02330	COG0740	serine-type endopeptidase activity
FBF59_RS02390	COG4824	toxin secretion phage lysis holin
FBF59_RS02455	COG1309	transcriptional regulator
FBF59_RS02460	COG0488	(ABC) transporter
FBF59_RS02505	COG0457	Tetratricopeptide repeat
FBF59_RS02525	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FBF59_RS02545	COG0697	spore germination
FBF59_RS02555	COG3397	chitin binding
FBF59_RS02560	COG0823	Involved in the tonB-independent uptake of proteins
FBF59_RS02570	COG0463	Glycosyl transferase, family 2
FBF59_RS02575	COG0463	Glycosyl transferase, family 2
FBF59_RS02580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FBF59_RS02590	COG1088	dTDP-glucose 4,6-dehydratase activity
FBF59_RS02595	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FBF59_RS02600	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FBF59_RS02615	COG2089	acid synthase
FBF59_RS02625	COG4641	Protein conserved in bacteria
FBF59_RS02640	COG1252	NADH dehydrogenase
FBF59_RS02660	COG0277	FAD linked oxidase domain protein
FBF59_RS02665	COG0385	Bile acid
FBF59_RS02675	COG0457	Tetratricopeptide repeat
FBF59_RS02685	COG0604	alcohol dehydrogenase
FBF59_RS02690	COG0640	Transcriptional regulator
FBF59_RS02700	COG0584	glycerophosphoryl diester phosphodiesterase
FBF59_RS02725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FBF59_RS02760	COG1164	Oligoendopeptidase f
FBF59_RS02765	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FBF59_RS02780	COG1193	negative regulation of DNA recombination
FBF59_RS02800	COG0583	DNA-binding transcription factor activity
FBF59_RS02830	COG3739	integral membrane protein
FBF59_RS02835	COG1247	-acetyltransferase
FBF59_RS02845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FBF59_RS02850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FBF59_RS02885	COG2814	Major facilitator Superfamily
FBF59_RS02890	COG1113	amino acid transport
FBF59_RS02895	COG0604	alcohol dehydrogenase
FBF59_RS02900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FBF59_RS02930	COG2072	flavoprotein involved in K transport
FBF59_RS02970	COG1151	hydroxylamine reductase activity
FBF59_RS03015	COG1191	sigma factor activity
FBF59_RS03040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FBF59_RS03045	COG1733	regulation of RNA biosynthetic process
FBF59_RS03050	COG2249	NAD(P)H dehydrogenase (quinone) activity
FBF59_RS03055	COG0318	PFAM AMP-dependent synthetase and ligase
FBF59_RS03065	COG0384	phenazine biosynthesis protein PhzF
FBF59_RS03090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FBF59_RS03110	COG0673	inositol 2-dehydrogenase activity
FBF59_RS03115	COG2188	Transcriptional regulator
FBF59_RS03120	COG1733	regulation of RNA biosynthetic process
FBF59_RS03150	COG0814	amino acid
FBF59_RS03170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FBF59_RS03175	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FBF59_RS03180	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FBF59_RS03185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FBF59_RS03190	COG1070	Carbohydrate kinase
FBF59_RS03195	COG2706	6-phosphogluconolactonase activity
FBF59_RS03200	COG3813	Protein conserved in bacteria
FBF59_RS03205	COG1357	PFAM Pentapeptide repeats (8 copies)
FBF59_RS03220	COG0697	spore germination
FBF59_RS03225	COG0789	Transcriptional regulator
FBF59_RS03230	COG1253	flavin adenine dinucleotide binding
FBF59_RS03260	COG0477	Major facilitator Superfamily
FBF59_RS03270	COG0500	methyltransferase
FBF59_RS03295	COG0628	permease
FBF59_RS03310	COG1136	(ABC) transporter
FBF59_RS03320	COG0110	maltose O-acetyltransferase activity
FBF59_RS03325	COG0738	Major facilitator superfamily
FBF59_RS03330	COG1940	carbohydrate kinase activity
FBF59_RS03335	COG0346	lactoylglutathione lyase activity
FBF59_RS03345	COG1051	belongs to the nudix hydrolase family
FBF59_RS03360	COG2365	Tyrosine phosphatase family
FBF59_RS03365	COG1011	Hydrolase
FBF59_RS03390	COG1131	(ABC) transporter
FBF59_RS03400	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS03430	COG0778	Nitroreductase
FBF59_RS03435	COG1733	regulation of RNA biosynthetic process
FBF59_RS03455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FBF59_RS03460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FBF59_RS03470	COG2356	endonuclease I
FBF59_RS03475	COG1288	antiporter activity
FBF59_RS03480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FBF59_RS03530	COG2249	NAD(P)H dehydrogenase (quinone) activity
FBF59_RS03545	COG2031	fatty acid transporter
FBF59_RS03555	COG2814	Major facilitator Superfamily
FBF59_RS03560	COG1846	Transcriptional regulator
FBF59_RS03575	COG0477	Major facilitator Superfamily
FBF59_RS03585	COG2843	Capsule synthesis protein
FBF59_RS03590	COG1876	peptidase activity
FBF59_RS03615	COG5444	nuclease activity
FBF59_RS03665	COG4282	regulation of fungal-type cell wall biogenesis
FBF59_RS03725	COG2814	Major facilitator Superfamily
FBF59_RS03740	COG5632	N-Acetylmuramoyl-L-alanine amidase
FBF59_RS03740	COG3409	Peptidoglycan-binding domain 1 protein
FBF59_RS03760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FBF59_RS03760	COG2207	Transcriptional regulator
FBF59_RS03770	COG0662	Cupin 2, conserved barrel domain protein
FBF59_RS03790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FBF59_RS03815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FBF59_RS03820	COG2808	Putative FMN-binding domain
FBF59_RS03825	COG0456	acetyltransferase
FBF59_RS03830	COG1846	Transcriptional regulator
FBF59_RS03835	COG2364	Membrane
FBF59_RS03845	COG3850	Histidine kinase
FBF59_RS03845	COG5002	protein histidine kinase activity
FBF59_RS03865	COG0577	efflux transmembrane transporter activity
FBF59_RS03885	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FBF59_RS03905	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FBF59_RS03915	COG2814	Major facilitator Superfamily
FBF59_RS03955	COG1136	(ABC) transporter
FBF59_RS03970	COG0277	FAD linked oxidase domain protein
FBF59_RS04015	COG0745	RESPONSE REGULATOR receiver
FBF59_RS04045	COG0346	lactoylglutathione lyase activity
FBF59_RS04060	COG1522	sequence-specific DNA binding
FBF59_RS04065	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS04070	COG1309	transcriptional regulator
FBF59_RS04075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FBF59_RS04075	COG3320	Male sterility
FBF59_RS04085	COG0825	malonyl-CoA metabolic process
FBF59_RS04100	COG1476	TRANSCRIPTIONal
FBF59_RS04140	COG0583	DNA-binding transcription factor activity
FBF59_RS04155	COG0640	Transcriptional regulator
FBF59_RS04160	COG0346	lactoylglutathione lyase activity
FBF59_RS04165	COG0798	PFAM Bile acid sodium symporter
FBF59_RS04185	COG1121	(ABC) transporter
FBF59_RS04190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FBF59_RS04195	COG0803	Belongs to the bacterial solute-binding protein 9 family
FBF59_RS04200	COG1575	Belongs to the MenA family. Type 1 subfamily
FBF59_RS04220	COG5609	conserved protein (DUF2294)
FBF59_RS04225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FBF59_RS04235	COG0288	reversible hydration of carbon dioxide
FBF59_RS04240	COG0415	Belongs to the DNA photolyase family
FBF59_RS04260	COG1073	alpha beta
FBF59_RS04285	COG0598	Magnesium transport protein CorA
FBF59_RS04290	COG1846	Transcriptional regulator
FBF59_RS04295	COG0583	DNA-binding transcription factor activity
FBF59_RS04315	COG1335	isochorismatase
FBF59_RS04325	COG0737	Belongs to the 5'-nucleotidase family
FBF59_RS04345	COG2124	cytochrome p450
FBF59_RS04355	COG1115	amino acid carrier protein
FBF59_RS04365	COG4191	Histidine kinase
FBF59_RS04370	COG0784	Response regulator, receiver
FBF59_RS04380	COG0531	amino acid
FBF59_RS04390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FBF59_RS04395	COG0531	amino acid
FBF59_RS04400	COG0322	excinuclease ABC activity
FBF59_RS04420	COG2207	Transcriptional regulator
FBF59_RS04445	COG5002	protein histidine kinase activity
FBF59_RS04475	COG1396	sequence-specific DNA binding
FBF59_RS04485	COG1027	Aspartate ammonia-lyase
FBF59_RS04495	COG1063	alcohol dehydrogenase
FBF59_RS04515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FBF59_RS04525	COG3848	Pyruvate phosphate dikinase
FBF59_RS04525	COG0574	Belongs to the PEP-utilizing enzyme family
FBF59_RS04565	COG3314	Sporulation integral membrane protein YlbJ
FBF59_RS04580	COG1960	acyl-CoA dehydrogenase activity
FBF59_RS04590	COG0640	Transcriptional regulator
FBF59_RS04605	COG1414	Transcriptional regulator
FBF59_RS04610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FBF59_RS04615	COG1984	allophanate hydrolase subunit 2
FBF59_RS04645	COG0768	penicillin binding
FBF59_RS04675	COG5002	protein histidine kinase activity
FBF59_RS04685	COG1329	Transcriptional regulator
FBF59_RS04740	COG0833	amino acid
FBF59_RS04750	COG0730	response to heat
FBF59_RS04795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FBF59_RS04800	COG0697	spore germination
FBF59_RS04805	COG2816	NAD+ diphosphatase activity
FBF59_RS04815	COG0456	acetyltransferase
FBF59_RS04820	COG2207	Transcriptional regulator
FBF59_RS04840	COG1136	(ABC) transporter
FBF59_RS04850	COG4884	unkown
FBF59_RS04850	COG3831	ATPase activity
FBF59_RS04875	COG1846	Transcriptional regulator
FBF59_RS04880	COG0778	Nitroreductase
FBF59_RS04935	COG0753	catalase activity
FBF59_RS04940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FBF59_RS04965	COG0714	Associated with various cellular activities
FBF59_RS04995	COG0346	lactoylglutathione lyase activity
FBF59_RS05000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FBF59_RS05020	COG3655	Transcriptional regulator
FBF59_RS05030	COG1785	Belongs to the alkaline phosphatase family
FBF59_RS05035	COG2720	vancomycin resistance protein
FBF59_RS05045	COG3239	Fatty acid desaturase
FBF59_RS05050	COG1690	Belongs to the RtcB family
FBF59_RS05060	COG0833	amino acid
FBF59_RS05070	COG1414	Transcriptional regulator
FBF59_RS05075	COG4187	Peptidase family M20/M25/M40
FBF59_RS05080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FBF59_RS05095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FBF59_RS05110	COG2329	Antibiotic biosynthesis monooxygenase
FBF59_RS05135	COG1070	Carbohydrate kinase
FBF59_RS05140	COG2390	Transcriptional regulator
FBF59_RS05150	COG1172	Belongs to the binding-protein-dependent transport system permease family
FBF59_RS05160	COG1879	ABC-type sugar transport system periplasmic component
FBF59_RS05190	COG1388	LysM domain
FBF59_RS05190	COG3584	3D domain protein
FBF59_RS05230	COG1605	Chorismate mutase
FBF59_RS05230	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FBF59_RS05245	COG0287	Prephenate dehydrogenase
FBF59_RS05260	COG1309	transcriptional regulator
FBF59_RS05265	COG2409	Drug exporters of the RND superfamily
FBF59_RS05265	COG1033	growth of symbiont in host cell
FBF59_RS05270	COG0488	(ABC) transporter
FBF59_RS05275	COG1368	sulfuric ester hydrolase activity
FBF59_RS05280	COG0861	Integral membrane protein TerC family
FBF59_RS05310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FBF59_RS05315	COG0346	lactoylglutathione lyase activity
FBF59_RS05320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FBF59_RS05325	COG4912	Dna alkylation repair
FBF59_RS05345	COG2318	DinB family
FBF59_RS05350	COG0697	spore germination
FBF59_RS05360	COG2746	aminoglycoside 3-N-acetyltransferase activity
FBF59_RS05390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FBF59_RS05395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FBF59_RS05410	COG0628	permease
FBF59_RS05455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FBF59_RS05460	COG0436	Aminotransferase
FBF59_RS05495	COG2226	methyltransferase
FBF59_RS05510	COG2261	transglycosylase associated protein
FBF59_RS05535	COG0477	Major facilitator Superfamily
FBF59_RS05535	COG2814	Major facilitator Superfamily
FBF59_RS05540	COG4533	DNA binding
FBF59_RS05545	COG0789	Transcriptional regulator
FBF59_RS05550	COG1664	Polymer-forming cytoskeletal
FBF59_RS05560	COG2814	Major facilitator Superfamily
FBF59_RS05600	COG1307	EDD domain protein, DegV family
FBF59_RS05605	COG1164	Oligoendopeptidase f
FBF59_RS05630	COG0745	RESPONSE REGULATOR receiver
FBF59_RS05635	COG3850	Histidine kinase
FBF59_RS05635	COG5002	protein histidine kinase activity
FBF59_RS05680	COG0667	Aldo Keto reductase
FBF59_RS05695	COG4948	Mandelate Racemase Muconate Lactonizing
FBF59_RS05705	COG4166	transmembrane transport
FBF59_RS05710	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FBF59_RS05720	COG0586	Pfam SNARE associated Golgi protein
FBF59_RS05765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FBF59_RS05770	COG3938	Belongs to the proline racemase family
FBF59_RS05780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FBF59_RS05785	COG1012	belongs to the aldehyde dehydrogenase family
FBF59_RS05790	COG1115	amino acid carrier protein
FBF59_RS05795	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FBF59_RS05810	COG3397	chitin binding
FBF59_RS05830	COG4637	Psort location Cytoplasmic, score
FBF59_RS05865	COG0514	ATP-dependent DNA helicase (RecQ)
FBF59_RS05880	COG3973	AAA domain
FBF59_RS05885	COG0456	acetyltransferase
FBF59_RS05935	COG2315	Protein conserved in bacteria
FBF59_RS05940	COG2267	carboxylic ester hydrolase activity
FBF59_RS05940	COG2226	methyltransferase
FBF59_RS05945	COG2205	protein histidine kinase activity
FBF59_RS05955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FBF59_RS05965	COG1819	glycosyl
FBF59_RS05970	COG3397	chitin binding
FBF59_RS05990	COG2153	protein acetylation
FBF59_RS06020	COG0517	IMP dehydrogenase activity
FBF59_RS06020	COG4175	Glycine betaine
FBF59_RS06025	COG4176	ABC-type proline glycine betaine transport system permease component
FBF59_RS06065	COG0456	acetyltransferase
FBF59_RS06065	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FBF59_RS06070	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS06080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FBF59_RS06085	COG0022	dehydrogenase e1 component
FBF59_RS06090	COG0508	dehydrogenase complex catalyzes the overall conversion of
FBF59_RS06095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FBF59_RS06110	COG1959	2 iron, 2 sulfur cluster binding
FBF59_RS06125	COG1349	DNA-binding transcription factor activity
FBF59_RS06140	COG3284	Transcriptional regulator
FBF59_RS06165	COG1309	transcriptional regulator
FBF59_RS06210	COG2959	enzyme of heme biosynthesis
FBF59_RS06225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FBF59_RS06260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FBF59_RS06265	COG0697	spore germination
FBF59_RS06270	COG0201	protein transport
FBF59_RS06275	COG0346	lactoylglutathione lyase activity
FBF59_RS06295	COG0737	Belongs to the 5'-nucleotidase family
FBF59_RS06300	COG3227	Zinc metalloprotease (Elastase)
FBF59_RS06305	COG1523	belongs to the glycosyl hydrolase 13 family
FBF59_RS06320	COG0076	glutamate decarboxylase activity
FBF59_RS06325	COG0657	acetylesterase activity
FBF59_RS06330	COG1073	alpha beta
FBF59_RS06335	COG0577	efflux transmembrane transporter activity
FBF59_RS06340	COG1136	(ABC) transporter
FBF59_RS06355	COG5002	protein histidine kinase activity
FBF59_RS06360	COG0745	RESPONSE REGULATOR receiver
FBF59_RS06365	COG1011	Hydrolase
FBF59_RS06390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FBF59_RS06405	COG1819	glycosyl
FBF59_RS06410	COG1819	glycosyl
FBF59_RS06445	COG0322	excinuclease ABC activity
FBF59_RS06485	COG4667	esterase of the alpha-beta hydrolase superfamily
FBF59_RS06505	COG3878	Protein conserved in bacteria
FBF59_RS06530	COG1051	belongs to the nudix hydrolase family
FBF59_RS06535	COG0592	DNA-directed DNA polymerase activity
FBF59_RS06550	COG2223	nitrite transmembrane transporter activity
FBF59_RS06555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FBF59_RS06565	COG0494	nUDIX hydrolase
FBF59_RS06590	COG0697	spore germination
FBF59_RS06595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FBF59_RS06615	COG0584	glycerophosphoryl diester phosphodiesterase
FBF59_RS06630	COG2814	Major facilitator Superfamily
FBF59_RS06675	COG0768	penicillin binding
FBF59_RS06680	COG0671	phosphoesterase, PA-phosphatase related
FBF59_RS06685	COG0604	alcohol dehydrogenase
FBF59_RS06690	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FBF59_RS06715	COG2169	Transcriptional regulator
FBF59_RS06775	COG2205	protein histidine kinase activity
FBF59_RS06815	COG1533	DNA photolyase activity
FBF59_RS06835	COG1090	epimerase
FBF59_RS06850	COG2155	Conserved Protein
FBF59_RS06860	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FBF59_RS06870	COG0415	Belongs to the DNA photolyase family
FBF59_RS06880	COG2814	Major facilitator Superfamily
FBF59_RS06890	COG0288	reversible hydration of carbon dioxide
FBF59_RS06905	COG0640	Transcriptional regulator
FBF59_RS06915	COG1181	Belongs to the D-alanine--D-alanine ligase family
FBF59_RS06915	COG2918	glutathione biosynthetic process
FBF59_RS06925	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FBF59_RS06935	COG1733	regulation of RNA biosynthetic process
FBF59_RS07000	COG1329	Transcriptional regulator
FBF59_RS07015	COG0662	Cupin 2, conserved barrel domain protein
FBF59_RS07070	COG1794	racemase activity, acting on amino acids and derivatives
FBF59_RS07075	COG1819	glycosyl
FBF59_RS07085	COG0768	penicillin binding
FBF59_RS07090	COG5002	protein histidine kinase activity
FBF59_RS07095	COG0561	phosphatase activity
FBF59_RS07135	COG2124	cytochrome p450
FBF59_RS07200	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FBF59_RS07210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FBF59_RS07235	COG0577	efflux transmembrane transporter activity
FBF59_RS07240	COG1136	(ABC) transporter
FBF59_RS07255	COG0488	(ABC) transporter
FBF59_RS07260	COG0667	Aldo Keto reductase
FBF59_RS07265	COG0583	DNA-binding transcription factor activity
FBF59_RS07270	COG2205	protein histidine kinase activity
FBF59_RS07275	COG0745	RESPONSE REGULATOR receiver
FBF59_RS07285	COG3773	Cell wall hydrolase
FBF59_RS07290	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FBF59_RS07300	COG3386	PFAM SMP-30 Gluconolaconase
FBF59_RS07310	COG0693	protein deglycase activity
FBF59_RS07320	COG2323	membrane
FBF59_RS07345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FBF59_RS07390	COG1733	regulation of RNA biosynthetic process
FBF59_RS07395	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS07405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FBF59_RS07440	COG3227	Zinc metalloprotease (Elastase)
FBF59_RS07455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FBF59_RS07485	COG1686	Belongs to the peptidase S11 family
FBF59_RS07525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FBF59_RS07530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FBF59_RS07535	COG1024	Enoyl-CoA hydratase
FBF59_RS07540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FBF59_RS07545	COG0511	ligase activity, forming carbon-carbon bonds
FBF59_RS07550	COG0439	Biotin carboxylase
FBF59_RS07555	COG1960	acyl-CoA dehydrogenase activity
FBF59_RS07570	COG1309	transcriptional regulator
FBF59_RS07590	COG1408	metallophosphoesterase
FBF59_RS07600	COG0768	penicillin binding
FBF59_RS07610	COG0768	penicillin binding
FBF59_RS07620	COG1595	DNA-templated transcription, initiation
FBF59_RS07625	COG0768	penicillin binding
FBF59_RS07685	COG1396	sequence-specific DNA binding
FBF59_RS07730	COG2814	Major facilitator Superfamily
FBF59_RS07735	COG2234	aminopeptidase activity
FBF59_RS07745	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FBF59_RS07760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FBF59_RS07765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FBF59_RS07770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FBF59_RS07780	COG0456	acetyltransferase
FBF59_RS07790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FBF59_RS07795	COG0741	lytic transglycosylase activity
FBF59_RS07855	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS07885	COG2814	Major facilitator Superfamily
FBF59_RS07900	COG1686	Belongs to the peptidase S11 family
FBF59_RS07910	COG0730	response to heat
FBF59_RS07920	COG2002	toxin-antitoxin pair type II binding
FBF59_RS07945	COG2195	Cleaves the N-terminal amino acid of tripeptides
FBF59_RS07985	COG3961	Belongs to the TPP enzyme family
FBF59_RS07990	COG2226	methyltransferase
FBF59_RS08000	COG0500	methyltransferase
FBF59_RS08000	COG3615	Tellurite resistance protein tehB
FBF59_RS08015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FBF59_RS08030	COG1846	Transcriptional regulator
FBF59_RS08040	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FBF59_RS08050	COG2971	BadF BadG BcrA BcrD
FBF59_RS08075	COG1649	PFAM Uncharacterised BCR, COG1649
FBF59_RS08095	COG1595	DNA-templated transcription, initiation
FBF59_RS08100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FBF59_RS08130	COG1396	sequence-specific DNA binding
FBF59_RS08160	COG1132	(ABC) transporter
FBF59_RS08165	COG1132	(ABC) transporter
FBF59_RS08180	COG2258	MOSC domain
FBF59_RS08185	COG0583	DNA-binding transcription factor activity
FBF59_RS08200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FBF59_RS08205	COG0583	DNA-binding transcription factor activity
FBF59_RS08235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FBF59_RS08245	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FBF59_RS08270	COG1247	-acetyltransferase
FBF59_RS08305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FBF59_RS08325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FBF59_RS08370	COG1136	(ABC) transporter
FBF59_RS08375	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FBF59_RS08380	COG1187	pseudouridine synthase activity
FBF59_RS08400	COG1115	amino acid carrier protein
FBF59_RS08410	COG2318	DinB family
FBF59_RS08420	COG0776	regulation of translation
FBF59_RS08435	COG2814	Major facilitator Superfamily
FBF59_RS08440	COG3251	PFAM MbtH domain protein
FBF59_RS08445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FBF59_RS08450	COG3433	isochorismatase activity
FBF59_RS08450	COG1535	isochorismatase
FBF59_RS08455	COG1021	2,3-dihydroxybenzoate-AMP ligase
FBF59_RS08460	COG1169	isochorismate synthase
FBF59_RS08465	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS08470	COG2223	nitrite transmembrane transporter activity
FBF59_RS08485	COG0419	ATPase involved in DNA repair
FBF59_RS08490	COG0420	3'-5' exonuclease activity
FBF59_RS08505	COG1024	Enoyl-CoA hydratase
FBF59_RS08510	COG1280	lysine exporter protein (LysE YggA)
FBF59_RS08520	COG2084	Dehydrogenase
FBF59_RS08525	COG1960	acyl-CoA dehydrogenase activity
FBF59_RS08530	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FBF59_RS08535	COG2079	MmgE PrpD family protein
FBF59_RS08540	COG0372	Belongs to the citrate synthase family
FBF59_RS08545	COG4841	protein insertion into membrane
FBF59_RS08550	COG2814	Major facilitator Superfamily
FBF59_RS08560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FBF59_RS08560	COG4499	WXG100 protein secretion system (Wss), protein YukC
FBF59_RS08580	COG0300	oxidoreductase activity
FBF59_RS08660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FBF59_RS08665	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FBF59_RS08670	COG0671	phosphoesterase, PA-phosphatase related
FBF59_RS08680	COG3064	Membrane
FBF59_RS08680	COG4991	sh3 domain protein
FBF59_RS08680	COG0515	serine threonine protein kinase
FBF59_RS08715	COG1509	lysine 2,3-aminomutase activity
FBF59_RS08720	COG3829	transcription factor binding
FBF59_RS08725	COG0456	acetyltransferase
FBF59_RS08730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FBF59_RS08735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FBF59_RS08740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FBF59_RS08745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FBF59_RS08760	COG5506	Protein of unknown function (DUF1694)
FBF59_RS08765	COG1012	belongs to the aldehyde dehydrogenase family
FBF59_RS08770	COG1253	flavin adenine dinucleotide binding
FBF59_RS08805	COG1174	glycine betaine transport
FBF59_RS08810	COG1125	glycine betaine transport
FBF59_RS08810	COG0517	IMP dehydrogenase activity
FBF59_RS08845	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FBF59_RS08855	COG1070	Carbohydrate kinase
FBF59_RS08870	COG1064	alcohol dehydrogenase
FBF59_RS08875	COG0384	phenazine biosynthesis protein PhzF
FBF59_RS08880	COG1737	Transcriptional regulator
FBF59_RS08885	COG2197	response regulator
FBF59_RS08890	COG2203	Gaf domain
FBF59_RS08890	COG4585	Histidine kinase
FBF59_RS08895	COG0668	transmembrane transport
FBF59_RS08900	COG1051	belongs to the nudix hydrolase family
FBF59_RS08905	COG1335	isochorismatase
FBF59_RS08925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FBF59_RS08930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FBF59_RS08935	COG0860	N-Acetylmuramoyl-L-alanine amidase
FBF59_RS08950	COG0367	asparagine synthase
FBF59_RS08955	COG0071	Belongs to the small heat shock protein (HSP20) family
FBF59_RS08960	COG1999	signal sequence binding
FBF59_RS08970	COG1307	EDD domain protein, DegV family
FBF59_RS08980	COG0805	protein transport
FBF59_RS08990	COG1272	protein, Hemolysin III
FBF59_RS08995	COG0204	Acyl-transferase
FBF59_RS09005	COG0768	penicillin binding
FBF59_RS09035	COG0546	phosphoglycolate phosphatase activity
FBF59_RS09050	COG1131	(ABC) transporter
FBF59_RS09060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FBF59_RS09065	COG3655	Transcriptional regulator
FBF59_RS09075	COG0456	acetyltransferase
FBF59_RS09085	COG1794	racemase activity, acting on amino acids and derivatives
FBF59_RS09095	COG2610	gluconate transmembrane transporter activity
FBF59_RS09125	COG0017	Asparaginyl-tRNA synthetase
FBF59_RS09170	COG0018	arginyl-trna synthetase
FBF59_RS09175	COG2136	Putative SAM-dependent methyltransferase
FBF59_RS09175	COG2521	methyltransferase
FBF59_RS09190	COG1413	lyase activity
FBF59_RS09200	COG0629	single-stranded DNA binding
FBF59_RS09215	COG0488	(ABC) transporter
FBF59_RS09220	COG1418	mRNA catabolic process
FBF59_RS09235	COG0457	Tetratricopeptide repeat
FBF59_RS09255	COG2359	stage V sporulation protein S
FBF59_RS09290	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FBF59_RS09295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FBF59_RS09300	COG2146	nitrite reductase [NAD(P)H] activity
FBF59_RS09305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FBF59_RS09305	COG1587	Uroporphyrinogen-III synthase
FBF59_RS09310	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
FBF59_RS09315	COG1648	precorrin-2 dehydrogenase activity
FBF59_RS09330	COG2223	nitrite transmembrane transporter activity
FBF59_RS09340	COG0314	molybdopterin synthase activity
FBF59_RS09345	COG0303	'Molybdopterin
FBF59_RS09350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FBF59_RS09355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FBF59_RS09360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FBF59_RS09365	COG2181	nitrate reductase activity
FBF59_RS09370	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FBF59_RS09375	COG1140	nitrate reductase beta subunit
FBF59_RS09380	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FBF59_RS09385	COG0714	Associated with various cellular activities
FBF59_RS09390	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FBF59_RS09395	COG1305	Transglutaminase-like
FBF59_RS09400	COG0386	Belongs to the glutathione peroxidase family
FBF59_RS09410	COG0426	domain, Protein
FBF59_RS09410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FBF59_RS09420	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FBF59_RS09430	COG1595	DNA-templated transcription, initiation
FBF59_RS09435	COG0604	alcohol dehydrogenase
FBF59_RS09445	COG0346	lactoylglutathione lyase activity
FBF59_RS09450	COG1082	Xylose isomerase domain protein TIM barrel
FBF59_RS09470	COG2226	methyltransferase
FBF59_RS09495	COG3874	Sporulation protein YtfJ
FBF59_RS09505	COG4974	Belongs to the 'phage' integrase family
FBF59_RS09660	COG0456	acetyltransferase
FBF59_RS09690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FBF59_RS09695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FBF59_RS09700	COG1819	glycosyl
FBF59_RS09715	COG4106	trans-aconitate 2-methyltransferase activity
FBF59_RS09720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FBF59_RS09730	COG2814	Major facilitator Superfamily
FBF59_RS09735	COG1846	Transcriptional regulator
FBF59_RS09740	COG0561	phosphatase activity
FBF59_RS09750	COG0860	N-Acetylmuramoyl-L-alanine amidase
FBF59_RS09765	COG2211	Major facilitator Superfamily
FBF59_RS09780	COG1876	peptidase activity
FBF59_RS09790	COG0860	N-Acetylmuramoyl-L-alanine amidase
FBF59_RS09810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FBF59_RS09815	COG1114	Component of the transport system for branched-chain amino acids
FBF59_RS09840	COG1253	flavin adenine dinucleotide binding
FBF59_RS09845	COG2839	Protein conserved in bacteria
FBF59_RS09850	COG0702	epimerase
FBF59_RS09865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FBF59_RS09875	COG1607	acyl-coa hydrolase
FBF59_RS09880	COG3689	TIGRFAM TIGR03943 family protein
FBF59_RS09885	COG0701	Predicted permease
FBF59_RS09895	COG2244	polysaccharide biosynthetic process
FBF59_RS09900	COG0586	Pfam SNARE associated Golgi protein
FBF59_RS09905	COG1051	belongs to the nudix hydrolase family
FBF59_RS09910	COG5337	Spore coat protein CotH
FBF59_RS09920	COG0406	alpha-ribazole phosphatase activity
FBF59_RS09935	COG4166	transmembrane transport
FBF59_RS09945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FBF59_RS09955	COG0702	epimerase
FBF59_RS09960	COG0803	Belongs to the bacterial solute-binding protein 9 family
FBF59_RS09965	COG0456	acetyltransferase
FBF59_RS09970	COG0523	cobalamin synthesis protein
FBF59_RS09975	COG4989	oxidoreductase activity
FBF59_RS09980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FBF59_RS09985	COG1231	oxidoreductase activity
FBF59_RS09995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FBF59_RS10010	COG0783	Belongs to the Dps family
FBF59_RS10015	COG3949	Membrane
FBF59_RS10035	COG0840	transmembrane signaling receptor activity
FBF59_RS10070	COG0667	Aldo Keto reductase
FBF59_RS10075	COG0640	Transcriptional regulator
FBF59_RS10080	COG1404	Belongs to the peptidase S8 family
FBF59_RS10085	COG2002	toxin-antitoxin pair type II binding
FBF59_RS10125	COG1752	Esterase of the alpha-beta hydrolase superfamily
FBF59_RS10135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FBF59_RS10140	COG1279	arginine transmembrane transporter activity
FBF59_RS10145	COG2814	Major facilitator Superfamily
FBF59_RS10155	COG1082	Xylose isomerase domain protein TIM barrel
FBF59_RS10165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FBF59_RS10185	COG1247	-acetyltransferase
FBF59_RS10190	COG1285	pathogenesis
FBF59_RS10205	COG1316	TRANSCRIPTIONal
FBF59_RS10230	COG0460	homoserine dehydrogenase
FBF59_RS10260	COG4122	O-methyltransferase activity
FBF59_RS10270	COG0300	oxidoreductase activity
FBF59_RS10275	COG5002	protein histidine kinase activity
FBF59_RS10280	COG0745	RESPONSE REGULATOR receiver
FBF59_RS10285	COG1132	(ABC) transporter
FBF59_RS10295	COG1388	LysM domain
FBF59_RS10295	COG0791	NLP P60 protein
FBF59_RS10310	COG1686	Belongs to the peptidase S11 family
FBF59_RS10350	COG1216	Glycosyl transferase, family 2
FBF59_RS10360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FBF59_RS10365	COG4988	ABC transporter
FBF59_RS10370	COG1294	oxidase, subunit
FBF59_RS10375	COG1271	oxidase subunit
FBF59_RS10405	COG0583	DNA-binding transcription factor activity
FBF59_RS10425	COG0411	ABC transporter
FBF59_RS10435	COG0523	cobalamin synthesis protein
FBF59_RS10445	COG1231	oxidoreductase activity
FBF59_RS10455	COG0628	permease
FBF59_RS10465	COG0778	Nitroreductase
FBF59_RS10470	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FBF59_RS10475	COG1959	2 iron, 2 sulfur cluster binding
FBF59_RS10480	COG0583	DNA-binding transcription factor activity
FBF59_RS10485	COG0697	spore germination
FBF59_RS10490	COG4549	nuclear export factor GLE1
FBF59_RS10495	COG2372	response to copper ion
FBF59_RS10495	COG1276	copper resistance
FBF59_RS10510	COG1114	Component of the transport system for branched-chain amino acids
FBF59_RS10530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FBF59_RS10545	COG2132	Multicopper oxidase
FBF59_RS10555	COG0006	proline dipeptidase activity
FBF59_RS10565	COG4846	Membrane protein involved in cytochrome C biogenesis
FBF59_RS10600	COG0295	cytidine deaminase activity
FBF59_RS10605	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FBF59_RS10610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FBF59_RS10620	COG2390	Transcriptional regulator
FBF59_RS10625	COG1309	transcriptional regulator
FBF59_RS10645	COG0456	acetyltransferase
FBF59_RS10660	COG2309	aminopeptidase activity
FBF59_RS10680	COG0531	amino acid
FBF59_RS10685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FBF59_RS10700	COG1914	H( )-stimulated, divalent metal cation uptake system
FBF59_RS10720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FBF59_RS10725	COG4166	transmembrane transport
FBF59_RS10745	COG0427	acetyl-CoA hydrolase
FBF59_RS10750	COG3279	Response regulator of the LytR AlgR family
FBF59_RS10765	COG3384	dioxygenase
FBF59_RS10770	COG2814	Major facilitator Superfamily
FBF59_RS10795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FBF59_RS10815	COG0028	Belongs to the TPP enzyme family
FBF59_RS10820	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FBF59_RS10830	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FBF59_RS10850	COG2323	membrane
FBF59_RS10855	COG5566	PFAM Mor transcription activator
FBF59_RS10865	COG0733	neurotransmitter:sodium symporter activity
FBF59_RS10885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FBF59_RS10890	COG2223	nitrite transmembrane transporter activity
FBF59_RS10895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FBF59_RS10905	COG0477	Major facilitator Superfamily
FBF59_RS10915	COG1695	Transcriptional regulator
FBF59_RS10930	COG2814	Major facilitator Superfamily
FBF59_RS10985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FBF59_RS10990	COG0784	Response regulator, receiver
FBF59_RS10995	COG4191	Histidine kinase
FBF59_RS11000	COG0281	malic enzyme
FBF59_RS11005	COG1027	Aspartate ammonia-lyase
FBF59_RS11015	COG0528	UMP kinase activity
FBF59_RS11020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FBF59_RS11035	COG1131	(ABC) transporter
FBF59_RS11075	COG2733	membrane
FBF59_RS11095	COG0457	Tetratricopeptide repeat
FBF59_RS11105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FBF59_RS11110	COG0785	Cytochrome C biogenesis protein
FBF59_RS11130	COG3340	Belongs to the peptidase S51 family
FBF59_RS11135	COG0534	Mate efflux family protein
FBF59_RS11165	COG0789	Transcriptional regulator
FBF59_RS11170	COG1757	Na H antiporter
FBF59_RS11175	COG1216	Glycosyl transferase, family 2
FBF59_RS11175	COG0438	transferase activity, transferring glycosyl groups
FBF59_RS11185	COG0701	Predicted permease
FBF59_RS11195	COG0523	cobalamin synthesis protein
FBF59_RS11235	COG0367	asparagine synthase
FBF59_RS11245	COG1846	Transcriptional regulator
FBF59_RS11265	COG0406	alpha-ribazole phosphatase activity
FBF59_RS11300	COG1234	tRNA 3'-trailer cleavage
FBF59_RS11320	COG0583	DNA-binding transcription factor activity
FBF59_RS11345	COG1215	transferase activity, transferring glycosyl groups
FBF59_RS11350	COG2329	Antibiotic biosynthesis monooxygenase
FBF59_RS11380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FBF59_RS11385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FBF59_RS11390	COG4786	Flagellar basal body rod
FBF59_RS11395	COG1419	protein localization to endoplasmic reticulum
FBF59_RS11400	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FBF59_RS11405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FBF59_RS11415	COG1987	bacterial-type flagellum assembly
FBF59_RS11420	COG1338	Plays a role in the flagellum-specific transport system
FBF59_RS11430	COG1776	CheC inhibitor of MCP methylation
FBF59_RS11430	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FBF59_RS11435	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FBF59_RS11445	COG0741	lytic transglycosylase activity
FBF59_RS11450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FBF59_RS11480	COG0784	Response regulator, receiver
FBF59_RS11480	COG0835	chemotaxis
FBF59_RS11495	COG1749	Flagellar hook protein flgE
FBF59_RS11515	COG1157	protein secretion by the type III secretion system
FBF59_RS11525	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FBF59_RS11530	COG1766	The M ring may be actively involved in energy transduction
FBF59_RS11540	COG1558	bacterial-type flagellum-dependent cell motility
FBF59_RS11545	COG1815	bacterial-type flagellum-dependent cell motility
FBF59_RS11565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FBF59_RS11570	COG1256	bacterial-type flagellum assembly
FBF59_RS11590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FBF59_RS11605	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FBF59_RS11605	COG1776	CheC inhibitor of MCP methylation
FBF59_RS11610	COG2198	Histidine kinase
FBF59_RS11610	COG0643	Histidine kinase
FBF59_RS11615	COG2201	protein-glutamate methylesterase activity
FBF59_RS11620	COG1360	Flagellar Motor Protein
FBF59_RS11625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FBF59_RS11635	COG1923	regulation of RNA biosynthetic process
FBF59_RS11675	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FBF59_RS11680	COG2323	membrane
FBF59_RS11690	COG0789	Transcriptional regulator
FBF59_RS11690	COG4978	Transcriptional regulator
FBF59_RS11700	COG0475	glutathione-regulated potassium exporter activity
FBF59_RS11710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FBF59_RS11715	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FBF59_RS11735	COG1280	lysine exporter protein (LysE YggA)
FBF59_RS11740	COG3403	YqcI/YcgG family
FBF59_RS11775	COG0328	RNA-DNA hybrid ribonuclease activity
FBF59_RS11795	COG0454	-acetyltransferase
FBF59_RS11810	COG0438	transferase activity, transferring glycosyl groups
FBF59_RS11815	COG1215	transferase activity, transferring glycosyl groups
FBF59_RS11830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FBF59_RS11840	COG3944	biosynthesis protein
FBF59_RS11855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FBF59_RS11875	COG0754	glutathionylspermidine amidase activity
FBF59_RS11910	COG0456	acetyltransferase
FBF59_RS11920	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FBF59_RS11925	COG2311	Membrane
FBF59_RS11930	COG2233	PERMEase
FBF59_RS11940	COG0024	Methionine aminopeptidase
FBF59_RS11945	COG3173	Aminoglycoside phosphotransferase
FBF59_RS11955	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FBF59_RS11960	COG1199	ATP-dependent helicase activity
FBF59_RS11970	COG0116	Belongs to the methyltransferase superfamily
FBF59_RS12025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FBF59_RS12025	COG4499	WXG100 protein secretion system (Wss), protein YukC
FBF59_RS12035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FBF59_RS12040	COG3935	DnaD domain protein
FBF59_RS12060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FBF59_RS12060	COG1199	ATP-dependent helicase activity
FBF59_RS12095	COG0438	transferase activity, transferring glycosyl groups
FBF59_RS12115	COG1694	Mazg nucleotide pyrophosphohydrolase
FBF59_RS12120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FBF59_RS12130	COG2738	Putative neutral zinc metallopeptidase
FBF59_RS12145	COG4347	Protein of unknown function (DUF1405)
FBF59_RS12150	COG2010	Cytochrome c
FBF59_RS12150	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FBF59_RS12155	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FBF59_RS12175	COG0457	Tetratricopeptide repeat
FBF59_RS12205	COG0142	geranyltranstransferase activity
FBF59_RS12215	COG0142	geranyltranstransferase activity
FBF59_RS12230	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FBF59_RS12295	COG0252	asparaginase activity
FBF59_RS12300	COG0492	ferredoxin-NADP+ reductase activity
FBF59_RS12320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FBF59_RS12330	COG0789	Transcriptional regulator
FBF59_RS12335	COG1408	metallophosphoesterase
FBF59_RS12345	COG1266	CAAX protease self-immunity
FBF59_RS12350	COG0514	ATP-dependent DNA helicase (RecQ)
FBF59_RS12360	COG1141	Ferredoxin
FBF59_RS12365	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FBF59_RS12375	COG4942	peptidase
FBF59_RS12380	COG2096	Adenosyltransferase
FBF59_RS12385	COG5002	protein histidine kinase activity
FBF59_RS12390	COG0745	RESPONSE REGULATOR receiver
FBF59_RS12395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FBF59_RS12400	COG1333	cytochrome c biogenesis protein
FBF59_RS12410	COG1187	pseudouridine synthase activity
FBF59_RS12415	COG0700	Nucleoside recognition
FBF59_RS12420	COG2715	membrane protein required for spore maturation
FBF59_RS12425	COG1686	Belongs to the peptidase S11 family
FBF59_RS12430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FBF59_RS12445	COG0392	lysyltransferase activity
FBF59_RS12445	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FBF59_RS12460	COG5002	protein histidine kinase activity
FBF59_RS12475	COG1801	Protein of unknown function DUF72
FBF59_RS12480	COG3852	Histidine kinase
FBF59_RS12495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FBF59_RS12500	COG1392	Phosphate transport regulator
FBF59_RS12505	COG0306	phosphate transporter
FBF59_RS12510	COG0730	response to heat
FBF59_RS12560	COG1114	Component of the transport system for branched-chain amino acids
FBF59_RS12570	COG2197	response regulator
FBF59_RS12580	COG4758	membrane
FBF59_RS12595	COG1757	Na H antiporter
FBF59_RS12615	COG0733	neurotransmitter:sodium symporter activity
FBF59_RS12620	COG1648	precorrin-2 dehydrogenase activity
FBF59_RS12640	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FBF59_RS12645	COG0529	Catalyzes the synthesis of activated sulfate
FBF59_RS12665	COG0019	diaminopimelate decarboxylase activity
FBF59_RS12675	COG1368	sulfuric ester hydrolase activity
FBF59_RS12680	COG1183	phosphatidylcholine synthase activity
FBF59_RS12695	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FBF59_RS12770	COG0440	acetolactate synthase activity
FBF59_RS12775	COG0028	Belongs to the TPP enzyme family
FBF59_RS12780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FBF59_RS12805	COG4709	membrane
FBF59_RS12810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FBF59_RS12815	COG1301	dicarboxylic acid transport
FBF59_RS12825	COG1846	Transcriptional regulator
FBF59_RS12870	COG0716	FMN binding
FBF59_RS12890	COG1696	Membrane protein involved in D-alanine export
FBF59_RS12900	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FBF59_RS12905	COG2070	2-Nitropropane dioxygenase
FBF59_RS12910	COG1619	proteins homologs of microcin C7 resistance protein MccF
FBF59_RS12920	COG1335	isochorismatase
FBF59_RS12930	COG1522	sequence-specific DNA binding
FBF59_RS12950	COG1131	(ABC) transporter
FBF59_RS12960	COG1131	(ABC) transporter
FBF59_RS12965	COG1725	Transcriptional regulator
FBF59_RS12970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FBF59_RS12975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FBF59_RS12980	COG1780	Probably involved in ribonucleotide reductase function
FBF59_RS13010	COG4873	Protein conserved in bacteria
FBF59_RS13025	COG0720	synthase
FBF59_RS13035	COG5002	protein histidine kinase activity
FBF59_RS13040	COG2318	DinB family
FBF59_RS13050	COG1846	Transcriptional regulator
FBF59_RS13055	COG3852	Histidine kinase
FBF59_RS13065	COG2861	carbohydrate metabolic process
FBF59_RS13075	COG0235	Class ii aldolase
FBF59_RS13085	COG1349	DNA-binding transcription factor activity
FBF59_RS13110	COG3842	ATPase activity
FBF59_RS13115	COG1840	ABC-type Fe3 transport system, periplasmic component
FBF59_RS13130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FBF59_RS13140	COG3243	poly(R)-hydroxyalkanoic acid synthase
FBF59_RS13145	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS13165	COG2030	dehydratase
FBF59_RS13175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FBF59_RS13180	COG0861	Integral membrane protein TerC family
FBF59_RS13185	COG2116	formate transmembrane transporter activity
FBF59_RS13195	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FBF59_RS13215	COG2186	Transcriptional regulator
FBF59_RS13220	COG5002	protein histidine kinase activity
FBF59_RS13225	COG0745	RESPONSE REGULATOR receiver
FBF59_RS13235	COG3835	regulator
FBF59_RS13240	COG0277	FAD linked oxidase domain protein
FBF59_RS13245	COG0247	lactate metabolic process
FBF59_RS13250	COG2340	Cysteine-rich secretory protein family
FBF59_RS13260	COG0564	pseudouridine synthase activity
FBF59_RS13270	COG2409	Drug exporters of the RND superfamily
FBF59_RS13275	COG0671	phosphoesterase, PA-phosphatase related
FBF59_RS13285	COG1177	transmembrane transport
FBF59_RS13290	COG1176	ABC-type spermidine putrescine transport system, permease component I
FBF59_RS13300	COG1012	belongs to the aldehyde dehydrogenase family
FBF59_RS13335	COG0681	Belongs to the peptidase S26 family
FBF59_RS13340	COG1686	Belongs to the peptidase S11 family
FBF59_RS13350	COG2226	methyltransferase
FBF59_RS13375	COG1668	transmembrane transport
FBF59_RS13380	COG4152	abc transporter atp-binding protein
FBF59_RS13415	COG1476	TRANSCRIPTIONal
FBF59_RS13425	COG0508	dehydrogenase complex catalyzes the overall conversion of
FBF59_RS13480	COG5634	Uncharacterized conserved protein (DUF2278)
FBF59_RS13485	COG1620	l-lactate permease
FBF59_RS13520	COG0512	Glutamine amidotransferase of anthranilate synthase
FBF59_RS13520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FBF59_RS13535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FBF59_RS13540	COG5492	domain, Protein
FBF59_RS13555	COG2382	esterase
FBF59_RS13565	COG2153	protein acetylation
FBF59_RS13610	COG1091	dTDP-4-dehydrorhamnose reductase activity
FBF59_RS13625	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FBF59_RS13665	COG1216	Glycosyl transferase, family 2
FBF59_RS13670	COG0772	Belongs to the SEDS family
FBF59_RS13685	COG0564	pseudouridine synthase activity
FBF59_RS13695	COG2357	RelA SpoT domain protein
FBF59_RS13705	COG4116	CYTH
FBF59_RS13710	COG2346	COG2346, Truncated hemoglobins
FBF59_RS13720	COG1164	Oligoendopeptidase f
FBF59_RS13730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FBF59_RS13740	COG0861	Integral membrane protein TerC family
FBF59_RS13760	COG4166	transmembrane transport
FBF59_RS13765	COG0534	Mate efflux family protein
FBF59_RS13770	COG4608	Belongs to the ABC transporter superfamily
FBF59_RS13775	COG0444	Belongs to the ABC transporter superfamily
FBF59_RS13780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FBF59_RS13785	COG0601	transmembrane transport
FBF59_RS13790	COG4166	transmembrane transport
FBF59_RS13810	COG0180	Tryptophanyl-tRNA synthetase
FBF59_RS13820	COG5504	Zn-dependent protease
FBF59_RS13825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FBF59_RS13830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FBF59_RS13845	COG2267	carboxylic ester hydrolase activity
FBF59_RS13865	COG0561	phosphatase activity
FBF59_RS13880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FBF59_RS13940	COG3209	COG3209 Rhs family protein
FBF59_RS13945	COG2996	Protein conserved in bacteria
FBF59_RS13970	COG0004	ammonium transporteR
FBF59_RS13975	COG0753	catalase activity
FBF59_RS13985	COG0367	asparagine synthase
FBF59_RS14015	COG0179	Fumarylacetoacetate (FAA) hydrolase
FBF59_RS14075	COG0398	Pfam SNARE associated Golgi protein
FBF59_RS14080	COG4903	ComK protein
FBF59_RS14095	COG1278	Cold shock
FBF59_RS14110	COG2224	Isocitrate lyase
FBF59_RS14115	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FBF59_RS14125	COG3693	PFAM glycoside hydrolase, family 10
FBF59_RS14135	COG0840	transmembrane signaling receptor activity
FBF59_RS14140	COG0501	Belongs to the peptidase M48B family
FBF59_RS14160	COG0745	RESPONSE REGULATOR receiver
FBF59_RS14165	COG2205	protein histidine kinase activity
FBF59_RS14180	COG2207	Transcriptional regulator
FBF59_RS14180	COG3708	Transcriptional regulator
FBF59_RS14190	COG1595	DNA-templated transcription, initiation
FBF59_RS14200	COG1078	dGTPase activity
FBF59_RS14205	COG1408	metallophosphoesterase
FBF59_RS14210	COG1073	alpha beta
FBF59_RS14270	COG0318	PFAM AMP-dependent synthetase and ligase
FBF59_RS14280	COG0095	Lipoate-protein ligase
FBF59_RS14285	COG1234	tRNA 3'-trailer cleavage
FBF59_RS14295	COG1609	Transcriptional regulator
FBF59_RS14320	COG1511	domain protein
FBF59_RS14325	COG1309	transcriptional regulator
FBF59_RS14350	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FBF59_RS14365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FBF59_RS14370	COG2329	Antibiotic biosynthesis monooxygenase
FBF59_RS14380	COG3402	PFAM membrane-flanked domain
FBF59_RS14385	COG0697	spore germination
FBF59_RS14420	COG3428	Bacterial PH domain
FBF59_RS14425	COG3402	PFAM membrane-flanked domain
FBF59_RS14430	COG1309	transcriptional regulator
FBF59_RS14445	COG4473	ABC transporter
FBF59_RS14450	COG1131	(ABC) transporter
FBF59_RS14455	COG0537	adenosine 5'-monophosphoramidase activity
FBF59_RS14460	COG4980	gas vesicle protein
FBF59_RS14490	COG3973	AAA domain
FBF59_RS14515	COG1695	Transcriptional regulator
FBF59_RS14520	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FBF59_RS14530	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FBF59_RS14535	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FBF59_RS14545	COG3620	sequence-specific DNA binding
FBF59_RS14550	COG2140	Oxalate decarboxylase
FBF59_RS14575	COG2267	carboxylic ester hydrolase activity
FBF59_RS14590	COG0346	lactoylglutathione lyase activity
FBF59_RS14595	COG0346	lactoylglutathione lyase activity
FBF59_RS14600	COG1280	lysine exporter protein (LysE YggA)
FBF59_RS14615	COG4717	serine-type aminopeptidase activity
FBF59_RS14620	COG0420	3'-5' exonuclease activity
FBF59_RS14640	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FBF59_RS14685	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FBF59_RS14690	COG2208	phosphoserine phosphatase activity
FBF59_RS14700	COG1191	sigma factor activity
FBF59_RS14770	COG2373	Large extracellular alpha-helical protein
FBF59_RS14835	COG2376	Dihydroxyacetone kinase
FBF59_RS14850	COG2376	Dihydroxyacetone kinase
FBF59_RS14865	COG0640	Transcriptional regulator
FBF59_RS14870	COG2814	Major facilitator Superfamily
FBF59_RS14880	COG1183	phosphatidylcholine synthase activity
FBF59_RS14945	COG1073	alpha beta
FBF59_RS15030	COG0477	Major facilitator Superfamily
FBF59_RS15060	COG0305	Participates in initiation and elongation during chromosome replication
FBF59_RS15080	COG0210	DNA helicase
FBF59_RS15120	COG3181	Tripartite tricarboxylate transporter family receptor
FBF59_RS15125	COG4565	transcriptional regulatory protein
FBF59_RS15130	COG3290	protein histidine kinase activity
FBF59_RS15135	COG0477	Major facilitator Superfamily
FBF59_RS15190	COG3157	Type VI secretion system effector, Hcp
FBF59_RS15250	COG2814	Major facilitator Superfamily
FBF59_RS15255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FBF59_RS15270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FBF59_RS15290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FBF59_RS15300	COG4608	Belongs to the ABC transporter superfamily
FBF59_RS15305	COG0444	Belongs to the ABC transporter superfamily
FBF59_RS15310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FBF59_RS15315	COG0601	transmembrane transport
FBF59_RS15350	COG1363	Peptidase, m42
FBF59_RS15370	COG1024	Enoyl-CoA hydratase
FBF59_RS15390	COG2244	polysaccharide biosynthetic process
FBF59_RS15395	COG0659	secondary active sulfate transmembrane transporter activity
FBF59_RS15405	COG0318	PFAM AMP-dependent synthetase and ligase
FBF59_RS15410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FBF59_RS15415	COG5632	N-Acetylmuramoyl-L-alanine amidase
FBF59_RS15415	COG3409	Peptidoglycan-binding domain 1 protein
FBF59_RS15425	COG0561	phosphatase activity
FBF59_RS15440	COG3527	Alpha-acetolactate decarboxylase
FBF59_RS15445	COG0028	Belongs to the TPP enzyme family
FBF59_RS15475	COG0189	ligase activity
FBF59_RS15490	COG1126	abc transporter atp-binding protein
FBF59_RS15495	COG0765	amino acid transport
FBF59_RS15500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FBF59_RS15510	COG1132	(ABC) transporter
FBF59_RS15515	COG1132	(ABC) transporter
FBF59_RS15525	COG1012	belongs to the aldehyde dehydrogenase family
FBF59_RS15530	COG0531	amino acid
FBF59_RS15540	COG0753	catalase activity
FBF59_RS15540	COG0693	protein deglycase activity
FBF59_RS15545	COG0693	protein deglycase activity
FBF59_RS15565	COG1733	regulation of RNA biosynthetic process
FBF59_RS15570	COG2814	Major facilitator Superfamily
FBF59_RS15575	COG1309	transcriptional regulator
FBF59_RS15590	COG0789	Transcriptional regulator
FBF59_RS15595	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS15605	COG1522	sequence-specific DNA binding
FBF59_RS15625	COG2259	Doxx family
FBF59_RS15635	COG1263	PTS System
FBF59_RS15635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FBF59_RS15645	COG1737	Transcriptional regulator
FBF59_RS15655	COG0475	glutathione-regulated potassium exporter activity
FBF59_RS15660	COG0531	amino acid
FBF59_RS15690	COG0586	Pfam SNARE associated Golgi protein
FBF59_RS15725	COG3546	catalase activity
FBF59_RS15730	COG1114	Component of the transport system for branched-chain amino acids
FBF59_RS15745	COG5522	Integral membrane protein (intg_mem_TP0381)
FBF59_RS15755	COG1136	(ABC) transporter
FBF59_RS15760	COG0577	efflux transmembrane transporter activity
FBF59_RS15765	COG1388	LysM domain
FBF59_RS15765	COG3584	3D domain protein
FBF59_RS15790	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FBF59_RS15795	COG1447	Phosphotransferase system cellobiose-specific component IIA
FBF59_RS15800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FBF59_RS15800	COG3711	transcriptional antiterminator
FBF59_RS15820	COG1283	sodium-dependent phosphate transmembrane transporter activity
FBF59_RS15825	COG0604	alcohol dehydrogenase
FBF59_RS15830	COG1316	TRANSCRIPTIONal
FBF59_RS15840	COG0730	response to heat
FBF59_RS15845	COG2210	Belongs to the sulfur carrier protein TusA family
FBF59_RS15855	COG0425	Belongs to the sulfur carrier protein TusA family
FBF59_RS15855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FBF59_RS15860	COG0425	Belongs to the sulfur carrier protein TusA family
FBF59_RS15865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FBF59_RS15865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FBF59_RS15870	COG0425	Belongs to the sulfur carrier protein TusA family
FBF59_RS15870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FBF59_RS15875	COG1937	Protein conserved in bacteria
FBF59_RS15895	COG2719	SpoVR family
FBF59_RS15900	COG0778	Nitroreductase
FBF59_RS15960	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS15965	COG2252	PERMEase
FBF59_RS15980	COG1846	Transcriptional regulator
FBF59_RS15985	COG2814	Major facilitator Superfamily
FBF59_RS15990	COG2205	protein histidine kinase activity
FBF59_RS16030	COG0351	phosphomethylpyrimidine kinase
FBF59_RS16035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FBF59_RS16045	COG2104	thiamine diphosphate biosynthetic process
FBF59_RS16050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FBF59_RS16055	COG0352	thiamine-phosphate diphosphorylase activity
FBF59_RS16060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FBF59_RS16065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FBF59_RS16070	COG1116	anion transmembrane transporter activity
FBF59_RS16075	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FBF59_RS16095	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FBF59_RS16215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FBF59_RS16225	COG0581	inorganic phosphate transmembrane transporter activity
FBF59_RS16230	COG0573	inorganic phosphate transmembrane transporter activity
FBF59_RS16235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FBF59_RS16245	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FBF59_RS16250	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FBF59_RS16260	COG0531	amino acid
FBF59_RS16265	COG0697	spore germination
FBF59_RS16270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FBF59_RS16285	COG4990	cell redox homeostasis
FBF59_RS16290	COG0833	amino acid
FBF59_RS16300	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FBF59_RS16315	COG0569	domain protein
FBF59_RS16315	COG0475	glutathione-regulated potassium exporter activity
FBF59_RS16325	COG2153	protein acetylation
FBF59_RS16340	COG2252	PERMEase
FBF59_RS16345	COG1113	amino acid transport
FBF59_RS16360	COG1114	Component of the transport system for branched-chain amino acids
FBF59_RS16365	COG3104	oligopeptide transport
FBF59_RS16385	COG1476	TRANSCRIPTIONal
FBF59_RS16390	COG3583	domain protein
FBF59_RS16390	COG3584	3D domain protein
FBF59_RS16395	COG0840	transmembrane signaling receptor activity
FBF59_RS16445	COG1063	alcohol dehydrogenase
FBF59_RS16475	COG1879	ABC-type sugar transport system periplasmic component
FBF59_RS16480	COG1172	Belongs to the binding-protein-dependent transport system permease family
FBF59_RS16495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FBF59_RS16500	COG1609	Transcriptional regulator
FBF59_RS16505	COG0477	Major facilitator Superfamily
FBF59_RS16510	COG1846	Transcriptional regulator
FBF59_RS16515	COG2271	Major facilitator Superfamily
FBF59_RS16530	COG0659	secondary active sulfate transmembrane transporter activity
FBF59_RS16555	COG5002	protein histidine kinase activity
FBF59_RS16560	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FBF59_RS16565	COG2378	regulation of single-species biofilm formation
FBF59_RS16575	COG1595	DNA-templated transcription, initiation
FBF59_RS16590	COG0833	amino acid
FBF59_RS16595	COG0765	amino acid transport
FBF59_RS16600	COG0765	amino acid transport
FBF59_RS16605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FBF59_RS16610	COG1126	abc transporter atp-binding protein
FBF59_RS16620	COG1115	amino acid carrier protein
FBF59_RS16625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FBF59_RS16630	COG0697	spore germination
FBF59_RS16645	COG0366	Alpha amylase catalytic
FBF59_RS16650	COG1263	PTS System
FBF59_RS16650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FBF59_RS16655	COG2188	Transcriptional regulator
FBF59_RS16660	COG0531	amino acid
FBF59_RS16680	COG0714	Associated with various cellular activities
FBF59_RS16685	COG4548	von Willebrand factor, type A
FBF59_RS16695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FBF59_RS16700	COG0156	8-amino-7-oxononanoate synthase activity
FBF59_RS16715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FBF59_RS16720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FBF59_RS16725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FBF59_RS16730	COG3104	oligopeptide transport
FBF59_RS16745	COG1620	l-lactate permease
FBF59_RS16750	COG1027	Aspartate ammonia-lyase
FBF59_RS16755	COG1253	flavin adenine dinucleotide binding
FBF59_RS16760	COG0346	lactoylglutathione lyase activity
FBF59_RS16765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FBF59_RS16770	COG1316	TRANSCRIPTIONal
FBF59_RS16775	COG2720	vancomycin resistance protein
FBF59_RS16795	COG3227	Zinc metalloprotease (Elastase)
FBF59_RS16810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FBF59_RS16815	COG2217	Heavy metal translocating P-type atpase
FBF59_RS16820	COG0640	Transcriptional regulator
FBF59_RS16825	COG0531	amino acid
FBF59_RS16840	COG2427	Protein of unknown function (DUF1641)
FBF59_RS16845	COG3383	formate dehydrogenase (NAD+) activity
FBF59_RS16850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FBF59_RS16875	COG5002	protein histidine kinase activity
FBF59_RS16885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FBF59_RS16890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FBF59_RS16905	COG0281	malic enzyme
FBF59_RS16910	COG3493	citrate carrier protein
FBF59_RS16915	COG4565	transcriptional regulatory protein
FBF59_RS16920	COG3290	protein histidine kinase activity
FBF59_RS16930	COG4990	cell redox homeostasis
FBF59_RS16940	COG5002	protein histidine kinase activity
FBF59_RS16945	COG0745	RESPONSE REGULATOR receiver
FBF59_RS16950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FBF59_RS16960	COG0395	ABC-type sugar transport system, permease component
FBF59_RS16965	COG1175	transmembrane transport
FBF59_RS16970	COG3842	ATPase activity
FBF59_RS16975	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FBF59_RS17000	COG2851	Citrate transporter
FBF59_RS17005	COG4565	transcriptional regulatory protein
FBF59_RS17010	COG3290	protein histidine kinase activity
FBF59_RS17020	COG2268	Band 7 protein
FBF59_RS17025	COG1585	Membrane protein implicated in regulation of membrane protease activity
FBF59_RS17035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FBF59_RS17050	COG2766	serine protein kinase
FBF59_RS17060	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FBF59_RS17085	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FBF59_RS17205	COG0735	belongs to the Fur family
FBF59_RS17210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FBF59_RS17230	COG4555	ABC transporter
FBF59_RS17240	COG0069	glutamate synthase activity
FBF59_RS17240	COG0067	glutamate synthase
FBF59_RS17240	COG0070	glutamate synthase
FBF59_RS17245	COG4129	membrane
FBF59_RS17250	COG1132	(ABC) transporter
FBF59_RS17275	COG1194	a g-specific adenine glycosylase
FBF59_RS17280	COG1988	membrane-bound metal-dependent
FBF59_RS17310	COG1090	epimerase
FBF59_RS17315	COG1228	amidohydrolase
FBF59_RS17335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FBF59_RS17350	COG0463	Glycosyl transferase, family 2
FBF59_RS17355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FBF59_RS17355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FBF59_RS17365	COG0463	Glycosyl transferase, family 2
FBF59_RS17380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FBF59_RS17390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FBF59_RS17390	COG1263	PTS System
FBF59_RS17420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FBF59_RS17425	COG0833	amino acid
FBF59_RS17435	COG3829	transcription factor binding
FBF59_RS17460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FBF59_RS17465	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FBF59_RS17485	COG0535	radical SAM domain protein
FBF59_RS17495	COG0387	Pfam Sodium calcium exchanger
FBF59_RS17500	COG3871	stress protein (general stress protein 26)
FBF59_RS17515	COG0586	Pfam SNARE associated Golgi protein
FBF59_RS17525	COG0681	Belongs to the peptidase S26 family
FBF59_RS17535	COG0697	spore germination
FBF59_RS17540	COG2217	Heavy metal translocating P-type atpase
FBF59_RS17545	COG1295	ribonuclease BN
FBF59_RS17555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FBF59_RS17570	COG3853	Toxic anion resistance protein (TelA)
FBF59_RS17580	COG0861	Integral membrane protein TerC family
FBF59_RS17585	COG2310	stress, protein
FBF59_RS17590	COG2310	stress, protein
FBF59_RS17595	COG2310	stress, protein
FBF59_RS17625	COG2270	Major facilitator Superfamily
FBF59_RS17675	COG0488	(ABC) transporter
FBF59_RS17680	COG1116	anion transmembrane transporter activity
FBF59_RS17685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FBF59_RS17690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FBF59_RS17710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FBF59_RS17740	COG1263	PTS System
FBF59_RS17740	COG2190	(PTS) system
FBF59_RS17740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FBF59_RS17745	COG0366	Alpha amylase catalytic
FBF59_RS17750	COG0277	FAD linked oxidase domain protein
FBF59_RS17760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FBF59_RS17765	COG0549	Belongs to the carbamate kinase family
FBF59_RS17790	COG0840	transmembrane signaling receptor activity
FBF59_RS17795	COG1126	abc transporter atp-binding protein
FBF59_RS17800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FBF59_RS17805	COG0765	amino acid transport
FBF59_RS17815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FBF59_RS17815	COG0723	plastoquinol--plastocyanin reductase activity
FBF59_RS17820	COG2814	Major facilitator Superfamily
FBF59_RS17825	COG3541	Predicted nucleotidyltransferase
FBF59_RS17845	COG5002	protein histidine kinase activity
FBF59_RS17870	COG0166	Belongs to the GPI family
FBF59_RS17895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FBF59_RS17900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FBF59_RS17905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FBF59_RS17920	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FBF59_RS17930	COG0450	alkyl hydroperoxide reductase
FBF59_RS17945	COG1473	amidohydrolase
FBF59_RS17950	COG1757	Na H antiporter
FBF59_RS17980	COG4807	Protein conserved in bacteria
FBF59_RS17985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FBF59_RS17995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FBF59_RS18010	COG2309	aminopeptidase activity
FBF59_RS18020	COG2076	Multidrug Resistance protein
FBF59_RS18025	COG1012	belongs to the aldehyde dehydrogenase family
FBF59_RS18035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FBF59_RS18040	COG0546	phosphoglycolate phosphatase activity
FBF59_RS18045	COG1597	lipid kinase activity
FBF59_RS18065	COG4682	membrane
FBF59_RS18070	COG1846	Transcriptional regulator
FBF59_RS18075	COG0003	Pfam Anion-transporting ATPase
FBF59_RS18090	COG1464	Belongs to the NlpA lipoprotein family
FBF59_RS18095	COG2011	ABC-type metal ion transport system permease component
FBF59_RS18110	COG1335	isochorismatase
FBF59_RS18125	COG4851	CamS sex pheromone cAM373 precursor
FBF59_RS18135	COG0210	DNA helicase
FBF59_RS18160	COG0151	Belongs to the GarS family
FBF59_RS18170	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FBF59_RS18180	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FBF59_RS18195	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FBF59_RS18205	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FBF59_RS18210	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FBF59_RS18215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FBF59_RS18240	COG0697	spore germination
FBF59_RS18260	COG0745	RESPONSE REGULATOR receiver
FBF59_RS18265	COG2205	protein histidine kinase activity
FBF59_RS18310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FBF59_RS18330	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FBF59_RS18360	COG5002	protein histidine kinase activity
FBF59_RS18370	COG2252	PERMEase
FBF59_RS18380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FBF59_RS18395	COG2946	Replication initiation factor
FBF59_RS18405	COG1674	ftsk spoiiie
FBF59_RS18510	COG0582	viral genome integration into host DNA
FBF59_RS18525	COG1266	CAAX protease self-immunity
FBF59_RS18540	COG0488	(ABC) transporter
FBF59_RS18550	COG0456	acetyltransferase
FBF59_RS18555	COG1214	PFAM Peptidase M22, glycoprotease
FBF59_RS18560	COG0802	atpase or kinase
FBF59_RS18660	COG2183	response to ionizing radiation
FBF59_RS18665	COG2337	Toxic component of a toxin-antitoxin (TA) module
FBF59_RS18670	COG0864	Transcriptional regulator
FBF59_RS18675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FBF59_RS18680	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FBF59_RS18690	COG0705	Rhomboid family
FBF59_RS18695	COG4294	response to UV
FBF59_RS18705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FBF59_RS18715	COG2814	Major facilitator Superfamily
FBF59_RS18720	COG0531	amino acid
FBF59_RS18730	COG0179	Fumarylacetoacetate (FAA) hydrolase
FBF59_RS18735	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FBF59_RS18760	COG0561	phosphatase activity
FBF59_RS18765	COG4608	Belongs to the ABC transporter superfamily
FBF59_RS18770	COG0444	Belongs to the ABC transporter superfamily
FBF59_RS18775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FBF59_RS18780	COG0601	transmembrane transport
FBF59_RS18785	COG0747	negative chemotaxis
FBF59_RS18800	COG0488	(ABC) transporter
FBF59_RS18820	COG5298	Protein conserved in bacteria
FBF59_RS18835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FBF59_RS18845	COG1609	Transcriptional regulator
FBF59_RS18855	COG0204	Acyl-transferase
FBF59_RS18870	COG0697	spore germination
FBF59_RS18885	COG1910	domain protein
FBF59_RS18890	COG0725	ABC transporter, periplasmic molybdate-binding protein
FBF59_RS18895	COG4149	molybdate abc transporter
FBF59_RS18910	COG0656	L-ascorbic acid biosynthetic process
FBF59_RS18915	COG4166	transmembrane transport
FBF59_RS18920	COG4166	transmembrane transport
FBF59_RS18935	COG4166	transmembrane transport
FBF59_RS18940	COG4608	Belongs to the ABC transporter superfamily
FBF59_RS18945	COG0444	Belongs to the ABC transporter superfamily
FBF59_RS18950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FBF59_RS18955	COG0601	transmembrane transport
FBF59_RS18975	COG2814	Major facilitator Superfamily
FBF59_RS18985	COG2271	Major facilitator Superfamily
FBF59_RS18990	COG0277	FAD linked oxidase domain protein
FBF59_RS19000	COG0604	alcohol dehydrogenase
FBF59_RS19005	COG1464	Belongs to the NlpA lipoprotein family
FBF59_RS19010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FBF59_RS19015	COG2011	ABC-type metal ion transport system permease component
FBF59_RS19020	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS19055	COG4856	YbbR-like protein
FBF59_RS19060	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FBF59_RS19140	COG0726	polysaccharide deacetylase
FBF59_RS19145	COG2194	sulfuric ester hydrolase activity
FBF59_RS19155	COG0489	protein tyrosine kinase activity
FBF59_RS19160	COG0860	N-Acetylmuramoyl-L-alanine amidase
FBF59_RS19185	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FBF59_RS19220	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FBF59_RS19230	COG0024	Methionine aminopeptidase
FBF59_RS19240	COG0201	protein transport
FBF59_RS19300	COG0255	Belongs to the universal ribosomal protein uL29 family
FBF59_RS19340	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FBF59_RS19345	COG0051	transcription antitermination factor activity, RNA binding
FBF59_RS19370	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FBF59_RS19375	COG1358	cellular component organization or biogenesis
FBF59_RS19380	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FBF59_RS19390	COG2813	Specifically methylates the guanine in position
FBF59_RS19410	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FBF59_RS19415	COG0250	Participates in transcription elongation, termination and antitermination
FBF59_RS19420	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FBF59_RS19435	COG3688	RNA-binding protein containing a PIN domain
FBF59_RS19440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FBF59_RS19455	COG1045	serine acetyltransferase
FBF59_RS19475	COG4956	integral membrane protein (PIN domain superfamily)
FBF59_RS19485	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FBF59_RS19490	COG0542	response to heat
FBF59_RS19500	COG3880	PFAM UvrB UvrC protein
FBF59_RS19590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FBF59_RS19595	COG1396	sequence-specific DNA binding
FBF59_RS19600	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FBF59_RS19605	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FBF59_RS19610	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FBF59_RS19615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FBF59_RS19620	COG0512	Glutamine amidotransferase of anthranilate synthase
FBF59_RS19625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FBF59_RS19630	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FBF59_RS19645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FBF59_RS19650	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FBF59_RS19660	COG2208	phosphoserine phosphatase activity
FBF59_RS19675	COG1098	S1 RNA binding domain
FBF59_RS19695	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FBF59_RS19700	COG3956	TIGRFAM MazG family protein
FBF59_RS19705	COG2244	polysaccharide biosynthetic process
FBF59_RS19710	COG2002	toxin-antitoxin pair type II binding
FBF59_RS19715	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FBF59_RS19745	COG0251	oxidation-reduction process
FBF59_RS19750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FBF59_RS19765	COG4466	Protein conserved in bacteria
FBF59_RS19785	COG0084	hydrolase, TatD family'
FBF59_RS19795	COG2002	toxin-antitoxin pair type II binding
FBF59_RS19800	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FBF59_RS19810	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FBF59_RS19820	COG1774	PSP1 C-terminal conserved region
FBF59_RS19825	COG0470	DNA polymerase III
FBF59_RS19835	COG1982	Orn Lys Arg decarboxylase major
FBF59_RS19890	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FBF59_RS19900	COG0590	tRNA wobble adenosine to inosine editing
FBF59_RS19910	COG1335	isochorismatase
FBF59_RS19915	COG1428	Deoxynucleoside kinase
FBF59_RS19920	COG1428	Deoxynucleoside kinase
FBF59_RS19950	COG1686	Belongs to the peptidase S11 family
FBF59_RS19955	COG0516	GMP reductase activity
FBF59_RS19955	COG0517	IMP dehydrogenase activity
FBF59_RS19990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FBF59_RS19995	COG0187	DNA topoisomerase II activity
FBF59_RS20005	COG2501	S4 domain
FBF59_RS20010	COG0592	DNA-directed DNA polymerase activity
FBF59_RS20020	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FBF59_RS20035	COG1847	R3H domain protein
FBF59_RS20060	COG1192	Involved in chromosome partitioning
FBF59_RS20065	COG1475	DNA binding
FBF59_RS20075	COG0668	transmembrane transport
FBF59_RS20080	COG4481	Protein conserved in bacteria
FBF59_RS20085	COG0012	GTP binding
FBF59_RS20095	COG0629	single-stranded DNA binding
FBF59_RS20105	COG4241	membrane
FBF59_RS20110	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FBF59_RS20120	COG0305	Participates in initiation and elongation during chromosome replication
FBF59_RS20150	COG0745	RESPONSE REGULATOR receiver
FBF59_RS20155	COG5002	protein histidine kinase activity
FBF59_RS20165	COG4853	Protein conserved in bacteria
FBF59_RS20170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FBF59_RS20175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FBF59_RS20190	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FBF59_RS20235	COG0322	excinuclease ABC activity
FBF59_RS20240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FBF59_RS20285	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FBF59_RS20305	COG1164	Oligoendopeptidase f
FBF59_RS20325	COG1272	protein, Hemolysin III
FBF59_RS20330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FBF59_RS20365	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FBF59_RS20370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FBF59_RS20375	COG2814	Major facilitator Superfamily
FBF59_RS20380	COG3275	phosphorelay sensor kinase activity
FBF59_RS20400	COG0628	permease
FBF59_RS20405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FBF59_RS20405	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FBF59_RS20410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FBF59_RS20415	COG1309	transcriptional regulator
FBF59_RS20420	COG0488	(ABC) transporter
FBF59_RS20425	COG1309	transcriptional regulator
FBF59_RS20435	COG0463	Glycosyl transferase, family 2
FBF59_RS20440	COG4485	Bacterial membrane protein, YfhO
FBF59_RS20450	COG1216	Glycosyl transferase, family 2
FBF59_RS20465	COG1216	Glycosyl transferase, family 2
FBF59_RS20470	COG1607	acyl-coa hydrolase
FBF59_RS20480	COG0840	transmembrane signaling receptor activity
FBF59_RS20495	COG0438	transferase activity, transferring glycosyl groups
FBF59_RS20510	COG0477	Major facilitator Superfamily
FBF59_RS20515	COG3279	Response regulator of the LytR AlgR family
FBF59_RS20520	COG1966	Carbon starvation protein
FBF59_RS20525	COG2879	small protein
FBF59_RS20535	COG3706	GGDEF domain
FBF59_RS20540	COG0351	phosphomethylpyrimidine kinase
FBF59_RS20545	COG4585	Histidine kinase
FBF59_RS20545	COG2203	Gaf domain
FBF59_RS20550	COG2197	response regulator
FBF59_RS20560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FBF59_RS20565	COG1011	Hydrolase
FBF59_RS20570	COG2873	o-acetylhomoserine
FBF59_RS20580	COG0460	homoserine dehydrogenase
FBF59_RS20590	COG1609	Transcriptional regulator
FBF59_RS20595	COG2755	lipolytic protein G-D-S-L family
FBF59_RS20600	COG1131	(ABC) transporter
FBF59_RS20605	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FBF59_RS20615	COG2814	Major facilitator Superfamily
FBF59_RS20620	COG0561	phosphatase activity
FBF59_RS20625	COG2233	PERMEase
FBF59_RS20630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FBF59_RS20640	COG2363	Small membrane protein
FBF59_RS20650	COG3773	Cell wall hydrolase
FBF59_RS20670	COG0280	phosphate acetyltransferase
FBF59_RS20690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FBF59_RS20695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FBF59_RS20700	COG1120	ATPase activity
FBF59_RS20705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FBF59_RS20710	COG1078	dGTPase activity
FBF59_RS20720	COG1994	Peptidase M50
FBF59_RS20730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FBF59_RS20735	COG0584	glycerophosphoryl diester phosphodiesterase
FBF59_RS20740	COG0789	Transcriptional regulator
FBF59_RS20745	COG2814	Major facilitator Superfamily
FBF59_RS20770	COG1619	proteins homologs of microcin C7 resistance protein MccF
FBF59_RS20775	COG4506	Protein conserved in bacteria
FBF59_RS20785	COG1595	DNA-templated transcription, initiation
FBF59_RS20805	COG2234	aminopeptidase activity
FBF59_RS20815	COG0024	Methionine aminopeptidase
FBF59_RS20820	COG1131	(ABC) transporter
FBF59_RS20825	COG0842	Transport permease protein
FBF59_RS20830	COG4585	Histidine kinase
FBF59_RS20835	COG2197	response regulator
FBF59_RS20840	COG3227	Zinc metalloprotease (Elastase)
FBF59_RS20855	COG5001	Diguanylate cyclase
FBF59_RS20855	COG3300	MHYT domain
FBF59_RS20865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FBF59_RS20910	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FBF59_RS20915	COG1404	Belongs to the peptidase S8 family
FBF59_RS20955	COG3620	sequence-specific DNA binding
FBF59_RS20960	COG0247	lactate metabolic process
FBF59_RS20960	COG2181	nitrate reductase activity
FBF59_RS20965	COG0183	Belongs to the thiolase family
FBF59_RS20970	COG1250	3-hydroxyacyl-CoA dehydrogenase
FBF59_RS20975	COG1960	acyl-CoA dehydrogenase activity
FBF59_RS20980	COG1960	acyl-CoA dehydrogenase activity
FBF59_RS21000	COG4821	SIS domain
FBF59_RS21025	COG1494	fructose-1,6-bisphosphatase
FBF59_RS21030	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FBF59_RS21065	COG0009	L-threonylcarbamoyladenylate synthase
FBF59_RS21090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FBF59_RS21095	COG2259	Doxx family
FBF59_RS21100	COG2190	(PTS) system
FBF59_RS21110	COG0698	ribose 5-phosphate isomerase
FBF59_RS21145	COG0356	it plays a direct role in the translocation of protons across the membrane
FBF59_RS21195	COG5001	Diguanylate cyclase
FBF59_RS21195	COG3300	MHYT domain
FBF59_RS21210	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FBF59_RS21230	COG0839	Belongs to the complex I subunit 6 family
FBF59_RS21240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FBF59_RS21245	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FBF59_RS21250	COG1007	ATP synthesis coupled electron transport
FBF59_RS21255	COG4836	Membrane
FBF59_RS21270	COG2385	sporulation resulting in formation of a cellular spore
FBF59_RS21275	COG3279	Response regulator of the LytR AlgR family
FBF59_RS21290	COG0739	heme binding
FBF59_RS21300	COG1609	Transcriptional regulator
FBF59_RS21315	COG0489	protein tyrosine kinase activity
FBF59_RS21320	COG3944	biosynthesis protein
FBF59_RS21325	COG0489	protein tyrosine kinase activity
FBF59_RS21330	COG4464	protein tyrosine phosphatase activity
FBF59_RS21335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FBF59_RS21355	COG0438	transferase activity, transferring glycosyl groups
FBF59_RS21360	COG1215	transferase activity, transferring glycosyl groups
FBF59_RS21365	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FBF59_RS21370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FBF59_RS21375	COG1316	TRANSCRIPTIONal
FBF59_RS21385	COG0745	RESPONSE REGULATOR receiver
FBF59_RS21390	COG5002	protein histidine kinase activity
FBF59_RS21425	COG1136	(ABC) transporter
FBF59_RS21430	COG0577	efflux transmembrane transporter activity
FBF59_RS21470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FBF59_RS21475	COG4715	Zinc finger, swim domain protein
FBF59_RS21500	COG3584	3D domain protein
FBF59_RS21500	COG1388	LysM domain
FBF59_RS21510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FBF59_RS21515	COG1215	transferase activity, transferring glycosyl groups
FBF59_RS21525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FBF59_RS21530	COG0791	NLP P60 protein
FBF59_RS21530	COG1388	LysM domain
FBF59_RS21540	COG1368	sulfuric ester hydrolase activity
FBF59_RS21555	COG2389	metal-binding protein
FBF59_RS21565	COG1620	l-lactate permease
FBF59_RS21575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FBF59_RS21580	COG1294	oxidase, subunit
FBF59_RS21585	COG1271	oxidase subunit
FBF59_RS21595	COG0583	DNA-binding transcription factor activity
FBF59_RS21600	COG1511	domain protein
FBF59_RS21620	COG1301	dicarboxylic acid transport
FBF59_RS21625	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FBF59_RS21635	COG1447	Phosphotransferase system cellobiose-specific component IIA
FBF59_RS21645	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FBF59_RS21655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FBF59_RS21660	COG1447	Phosphotransferase system cellobiose-specific component IIA
FBF59_RS21665	COG1486	melibiose metabolic process
FBF59_RS21690	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FBF59_RS21690	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FBF59_RS21700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FBF59_RS21705	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FBF59_RS21710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FBF59_RS21715	COG1316	TRANSCRIPTIONal
FBF59_RS21720	COG1739	Uncharacterized protein family UPF0029
FBF59_RS21725	COG1307	EDD domain protein, DegV family
FBF59_RS21730	COG1733	regulation of RNA biosynthetic process
FBF59_RS21735	COG0791	NLP P60 protein
FBF59_RS21735	COG1388	LysM domain
FBF59_RS21740	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FBF59_RS21745	COG1040	competence protein
FBF59_RS21750	COG1278	Cold shock
FBF59_RS21755	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FBF59_RS21775	COG2884	Cell division ATP-binding protein ftsE
FBF59_RS21780	COG2177	Part of the ABC transporter FtsEX involved in
FBF59_RS21785	COG3409	Peptidoglycan-binding domain 1 protein
FBF59_RS21785	COG0793	Belongs to the peptidase S41A family
FBF59_RS21790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FBF59_RS21795	COG1132	(ABC) transporter
FBF59_RS21805	COG0488	(ABC) transporter
FBF59_RS21810	COG0655	NAD(P)H dehydrogenase (quinone) activity
FBF59_RS21820	COG0583	DNA-binding transcription factor activity
FBF59_RS21840	COG0789	Transcriptional regulator
FBF59_RS21860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FBF59_RS21870	COG1950	PFAM Membrane protein of
FBF59_RS21890	COG0110	maltose O-acetyltransferase activity
FBF59_RS21895	COG0457	Tetratricopeptide repeat
FBF59_RS21900	COG0492	ferredoxin-NADP+ reductase activity
FBF59_RS21910	COG1051	belongs to the nudix hydrolase family
FBF59_RS21920	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FBF59_RS21930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FBF59_RS21940	COG2323	membrane
FBF59_RS21955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FBF59_RS21980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FBF59_RS21995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FBF59_RS22030	COG1346	cytolysis
FBF59_RS22035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FBF59_RS22040	COG1647	Serine aminopeptidase, S33
FBF59_RS22045	COG0557	exoribonuclease II activity
FBF59_RS22090	COG2233	PERMEase
FBF59_RS22095	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FBF59_RS22100	COG0288	reversible hydration of carbon dioxide
FBF59_RS22105	COG1522	sequence-specific DNA binding
FBF59_RS22115	COG1522	sequence-specific DNA binding
FBF59_RS22120	COG1335	isochorismatase
FBF59_RS22140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FBF59_RS22145	COG0488	(ABC) transporter
FBF59_RS22180	COG3290	protein histidine kinase activity
FBF59_RS22180	COG0840	transmembrane signaling receptor activity
FBF59_RS22205	COG1252	NADH dehydrogenase
FBF59_RS22215	COG1733	regulation of RNA biosynthetic process
FBF59_RS22220	COG2814	Major facilitator Superfamily
FBF59_RS22225	COG0656	L-ascorbic acid biosynthetic process
FBF59_RS22240	COG2910	NAD(P)H-binding
FBF59_RS22245	COG1115	amino acid carrier protein
FBF59_RS22250	COG1115	amino acid carrier protein
FBF59_RS22255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FBF59_RS22265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FBF59_RS22275	COG1528	Iron-storage protein
FBF59_RS22285	COG1611	Belongs to the LOG family
FBF59_RS22300	COG0783	Belongs to the Dps family
FBF59_RS22305	COG1115	amino acid carrier protein
FBF59_RS22310	COG0490	domain, Protein
FBF59_RS22315	COG0475	glutathione-regulated potassium exporter activity
FBF59_RS22320	COG0586	Pfam SNARE associated Golgi protein
FBF59_RS22340	COG3227	Zinc metalloprotease (Elastase)
FBF59_RS22350	COG2151	metal-sulfur cluster biosynthetic enzyme
FBF59_RS22355	COG0840	transmembrane signaling receptor activity
FBF59_RS22385	COG5002	protein histidine kinase activity
FBF59_RS22390	COG0745	RESPONSE REGULATOR receiver
FBF59_RS22395	COG1376	ErfK ybiS ycfS ynhG family protein
FBF59_RS22405	COG0586	Pfam SNARE associated Golgi protein
FBF59_RS22450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FBF59_RS22475	COG0531	amino acid
FBF59_RS22480	COG2814	Major facilitator Superfamily
FBF59_RS22495	COG0840	transmembrane signaling receptor activity
FBF59_RS22500	COG0011	TIGRFAM Protein of
FBF59_RS22515	COG1686	Belongs to the peptidase S11 family
FBF59_RS22525	COG1250	3-hydroxyacyl-CoA dehydrogenase
FBF59_RS22525	COG1024	Enoyl-CoA hydratase
FBF59_RS22530	COG0183	Belongs to the thiolase family
FBF59_RS22535	COG1960	acyl-CoA dehydrogenase activity
FBF59_RS22540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FBF59_RS22555	COG0039	L-malate dehydrogenase activity
FBF59_RS22575	COG1393	Belongs to the ArsC family
FBF59_RS22585	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FBF59_RS22590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FBF59_RS22605	COG2011	ABC-type metal ion transport system permease component
FBF59_RS22610	COG1464	Belongs to the NlpA lipoprotein family
FBF59_RS22615	COG1464	Belongs to the NlpA lipoprotein family
FBF59_RS22620	COG0396	ATPase activity
FBF59_RS22625	COG0719	Fe-S assembly protein
FBF59_RS22630	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FBF59_RS22635	COG0822	iron-sulfur transferase activity
FBF59_RS22640	COG0719	Fe-S assembly protein
FBF59_RS22645	COG0737	Belongs to the 5'-nucleotidase family
FBF59_RS22650	COG3377	Domain of unknown function (DUF1805)
FBF59_RS22660	COG0739	heme binding
FBF59_RS22685	COG4377	Putative membrane peptidase family (DUF2324)
FBF59_RS22690	COG0789	Transcriptional regulator
FBF59_RS22700	COG4470	Protein conserved in bacteria
FBF59_RS22720	COG1494	fructose-1,6-bisphosphatase
FBF59_RS22725	COG2445	Protein of unknown function DUF86
FBF59_RS22735	COG0647	UMP catabolic process
FBF59_RS22740	COG2249	NAD(P)H dehydrogenase (quinone) activity
FBF59_RS22750	COG1358	cellular component organization or biogenesis
FBF59_RS22770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FBF59_RS22775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FBF59_RS22785	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FBF59_RS22790	COG4837	Protein of unknown function (DUF1462)
FBF59_RS22830	COG2824	Alkylphosphonate utilization operon protein PhnA
FBF59_RS22835	COG0390	transport system, permease component
FBF59_RS22840	COG2274	protein secretion by the type I secretion system
FBF59_RS22850	COG1252	NADH dehydrogenase
FBF59_RS22865	COG0316	Belongs to the HesB IscA family
FBF59_RS22900	COG1683	Conserved Protein
FBF59_RS22915	COG3708	Transcriptional regulator
FBF59_RS22925	COG1252	NADH dehydrogenase
FBF59_RS22940	COG3584	3D domain protein
FBF59_RS22955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FBF59_RS22960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FBF59_RS22965	COG1268	BioY protein
FBF59_RS22975	COG2050	protein possibly involved in aromatic compounds catabolism
FBF59_RS22995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FBF59_RS23000	COG5018	Exonuclease
FBF59_RS23015	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FBF59_RS23025	COG2267	carboxylic ester hydrolase activity
FBF59_RS23030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FBF59_RS23035	COG1522	sequence-specific DNA binding
FBF59_RS23040	COG0436	Aminotransferase
FBF59_RS23045	COG1098	S1 RNA binding domain
FBF59_RS23050	COG2155	Conserved Protein
FBF59_RS23070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FBF59_RS23075	COG1285	pathogenesis
FBF59_RS23210	COG1309	transcriptional regulator
FBF59_RS23240	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FBF59_RS23245	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FBF59_RS23255	COG0058	SHG alpha-glucan phosphorylase activity
FBF59_RS23275	COG1278	Cold shock
FBF59_RS23280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FBF59_RS23285	COG1575	Belongs to the MenA family. Type 1 subfamily
FBF59_RS23290	COG1169	isochorismate synthase
FBF59_RS23300	COG0596	Alpha beta hydrolase
FBF59_RS23305	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FBF59_RS23315	COG4948	Mandelate Racemase Muconate Lactonizing
FBF59_RS23340	COG3964	amidohydrolase
FBF59_RS23360	COG2188	Transcriptional regulator
FBF59_RS23375	COG0577	efflux transmembrane transporter activity
FBF59_RS23380	COG1136	(ABC) transporter
FBF59_RS23385	COG0577	efflux transmembrane transporter activity
FBF59_RS23390	COG0577	efflux transmembrane transporter activity
FBF59_RS23395	COG2205	protein histidine kinase activity
FBF59_RS23400	COG0745	RESPONSE REGULATOR receiver
FBF59_RS23410	COG0640	Transcriptional regulator
FBF59_RS23415	COG5658	integral membrane protein
FBF59_RS23420	COG1131	(ABC) transporter
FBF59_RS23430	COG2207	Transcriptional regulator
FBF59_RS23430	COG3708	Transcriptional regulator
FBF59_RS23435	COG1136	(ABC) transporter
FBF59_RS23440	COG0577	efflux transmembrane transporter activity
FBF59_RS23450	COG0586	Pfam SNARE associated Golgi protein
FBF59_RS23460	COG5002	protein histidine kinase activity
FBF59_RS23515	COG1597	lipid kinase activity
FBF59_RS23520	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FBF59_RS23545	COG0745	RESPONSE REGULATOR receiver
FBF59_RS23550	COG5002	protein histidine kinase activity
FBF59_RS23555	COG3859	Proton-coupled thiamine transporter YuaJ
FBF59_RS23580	COG1842	Phage shock protein A
FBF59_RS23605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FBF59_RS23625	COG1294	oxidase, subunit
FBF59_RS23630	COG1271	oxidase subunit
FBF59_RS23635	COG0288	reversible hydration of carbon dioxide
FBF59_RS23645	COG1854	S-ribosylhomocysteine lyase activity
FBF59_RS23650	COG0789	Transcriptional regulator
FBF59_RS23655	COG2076	Multidrug Resistance protein
FBF59_RS23660	COG2076	Multidrug Resistance protein
FBF59_RS23695	COG0494	nUDIX hydrolase
FBF59_RS23720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FBF59_RS23725	COG1116	anion transmembrane transporter activity
FBF59_RS23730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FBF59_RS23755	COG1368	sulfuric ester hydrolase activity
FBF59_RS23760	COG2267	carboxylic ester hydrolase activity
FBF59_RS23765	COG0753	catalase activity
FBF59_RS23770	COG3852	Histidine kinase
FBF59_RS23775	COG5002	protein histidine kinase activity
FBF59_RS23870	COG0438	transferase activity, transferring glycosyl groups
FBF59_RS23875	COG0671	phosphoesterase, PA-phosphatase related
FBF59_RS23880	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FBF59_RS23885	COG2267	carboxylic ester hydrolase activity
FBF59_RS23905	COG1794	racemase activity, acting on amino acids and derivatives
FBF59_RS23910	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FBF59_RS23915	COG1242	4 iron, 4 sulfur cluster binding
FBF59_RS23935	COG1136	(ABC) transporter
FBF59_RS23945	COG0582	viral genome integration into host DNA
FBF59_RS23950	COG0490	domain, Protein
FBF59_RS23955	COG0475	glutathione-regulated potassium exporter activity
FBF59_RS23960	COG2814	Major facilitator Superfamily
FBF59_RS24000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FBF59_RS24010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FBF59_RS24030	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FBF59_RS24035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FBF59_RS24045	COG0303	'Molybdopterin
FBF59_RS24050	COG1763	Mo-molybdopterin cofactor biosynthetic process
FBF59_RS24055	COG0314	molybdopterin synthase activity
FBF59_RS24080	COG1329	Transcriptional regulator
FBF59_RS24100	COG3832	glyoxalase III activity
FBF59_RS24110	COG2814	Major facilitator Superfamily
FBF59_RS24115	COG2081	HI0933 family
FBF59_RS24120	COG2244	polysaccharide biosynthetic process
FBF59_RS24125	COG1187	pseudouridine synthase activity
FBF59_RS24130	COG1349	DNA-binding transcription factor activity
FBF59_RS24135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FBF59_RS24145	COG1523	belongs to the glycosyl hydrolase 13 family
FBF59_RS24150	COG0510	thiamine kinase activity
FBF59_RS24165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FBF59_RS24175	COG1363	Peptidase, m42
FBF59_RS24180	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FBF59_RS24185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FBF59_RS24195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FBF59_RS24210	COG1674	ftsk spoiiie
FBF59_RS24225	COG0789	Transcriptional regulator
FBF59_RS24230	COG0697	spore germination
FBF59_RS24235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FBF59_RS24250	COG2309	aminopeptidase activity
FBF59_RS24260	COG3118	belongs to the thioredoxin family
FBF59_RS24265	COG4851	CamS sex pheromone cAM373 precursor
FBF59_RS24270	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FBF59_RS24270	COG1605	Chorismate mutase
FBF59_RS24275	COG1605	Chorismate mutase
FBF59_RS24275	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FBF59_RS24285	COG1609	Transcriptional regulator
FBF59_RS24320	COG0666	response to abiotic stimulus
FBF59_RS24325	COG5002	protein histidine kinase activity
FBF59_RS24330	COG0745	RESPONSE REGULATOR receiver
FBF59_RS24345	COG0123	including yeast histone deacetylase and acetoin utilization protein
FBF59_RS24350	COG0517	IMP dehydrogenase activity
FBF59_RS24355	COG0454	-acetyltransferase
FBF59_RS24360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FBF59_RS24365	COG0110	maltose O-acetyltransferase activity
FBF59_RS24390	COG0626	cystathionine gamma-synthase activity
FBF59_RS24395	COG1956	GAF domain-containing protein
FBF59_RS24400	COG1309	transcriptional regulator
FBF59_RS24405	COG0697	spore germination
FBF59_RS24410	COG0583	DNA-binding transcription factor activity
FBF59_RS24420	COG1104	cysteine desulfurase activity
FBF59_RS24435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FBF59_RS24445	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FBF59_RS24460	COG3874	Sporulation protein YtfJ
FBF59_RS24465	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FBF59_RS24470	COG0827	DNA restriction-modification system
FBF59_RS24495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FBF59_RS24540	COG0589	response to stress
FBF59_RS24545	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS24560	COG0662	Cupin 2, conserved barrel domain protein
FBF59_RS24565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FBF59_RS24600	COG0006	proline dipeptidase activity
FBF59_RS24610	COG4109	DRTGG domain
FBF59_RS24625	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FBF59_RS24640	COG0587	DNA-directed DNA polymerase activity
FBF59_RS24645	COG0281	malic enzyme
FBF59_RS24650	COG1725	Transcriptional regulator
FBF59_RS24675	COG3030	protein affecting phage T7 exclusion by the F plasmid
FBF59_RS24680	COG0628	permease
FBF59_RS24695	COG0372	Belongs to the citrate synthase family
FBF59_RS24700	COG0538	isocitrate dehydrogenase activity
FBF59_RS24720	COG0745	RESPONSE REGULATOR receiver
FBF59_RS24725	COG5002	protein histidine kinase activity
FBF59_RS24730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FBF59_RS24730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FBF59_RS24740	COG1971	Probably functions as a manganese efflux pump
FBF59_RS24745	COG0237	dephospho-CoA kinase activity
FBF59_RS24750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FBF59_RS24755	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FBF59_RS24765	COG3611	Membrane attachment protein
FBF59_RS24770	COG1484	DNA-dependent DNA replication
FBF59_RS24785	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FBF59_RS24810	COG1363	Peptidase, m42
FBF59_RS24815	COG1309	transcriptional regulator
FBF59_RS24820	COG1566	PFAM secretion protein HlyD family protein
FBF59_RS24825	COG2814	Major facilitator Superfamily
FBF59_RS24840	COG1418	mRNA catabolic process
FBF59_RS24850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FBF59_RS24890	COG1286	toxin biosynthetic process
FBF59_RS24895	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FBF59_RS24895	COG1796	DNA polymerase
FBF59_RS24905	COG1187	pseudouridine synthase activity
FBF59_RS24910	COG1114	Component of the transport system for branched-chain amino acids
FBF59_RS24915	COG5386	Cell surface protein
FBF59_RS24925	COG5386	Cell surface protein
FBF59_RS24940	COG1120	ATPase activity
FBF59_RS24945	COG4509	Sortase family
FBF59_RS24955	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FBF59_RS24960	COG4895	conserved protein (DUF2196)
FBF59_RS24965	COG0745	RESPONSE REGULATOR receiver
FBF59_RS24970	COG2205	protein histidine kinase activity
FBF59_RS24975	COG1131	(ABC) transporter
FBF59_RS24990	COG2318	DinB family
FBF59_RS25015	COG0318	PFAM AMP-dependent synthetase and ligase
FBF59_RS25020	COG1309	transcriptional regulator
FBF59_RS25025	COG1024	Enoyl-CoA hydratase
FBF59_RS25030	COG2086	electron transfer activity
FBF59_RS25035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FBF59_RS25040	COG3118	belongs to the thioredoxin family
FBF59_RS25050	COG1719	4-vinyl reductase, 4VR
FBF59_RS25055	COG2009	succinate dehydrogenase
FBF59_RS25060	COG1053	succinate dehydrogenase
FBF59_RS25065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FBF59_RS25070	COG0824	Thioesterase
FBF59_RS25075	COG1876	peptidase activity
FBF59_RS25080	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FBF59_RS25085	COG1360	Flagellar Motor Protein
FBF59_RS25090	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FBF59_RS25095	COG4152	abc transporter atp-binding protein
FBF59_RS25100	COG1668	transmembrane transport
FBF59_RS25105	COG1959	2 iron, 2 sulfur cluster binding
FBF59_RS25115	COG0697	spore germination
FBF59_RS25120	COG1396	sequence-specific DNA binding
FBF59_RS25125	COG1983	PspC domain protein
FBF59_RS25130	COG0402	S-adenosylhomocysteine deaminase activity
FBF59_RS25135	COG2233	PERMEase
FBF59_RS25140	COG2197	response regulator
FBF59_RS25150	COG1309	transcriptional regulator
FBF59_RS25170	COG5401	PFAM Sporulation and spore germination
FBF59_RS25185	COG0622	Phosphoesterase
FBF59_RS25235	COG0470	DNA polymerase III
FBF59_RS25235	COG1067	ATP-dependent peptidase activity
FBF59_RS25250	COG1764	response to oxidative stress
FBF59_RS25255	COG1846	Transcriptional regulator
FBF59_RS25265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FBF59_RS25275	COG1587	Uroporphyrinogen-III synthase
FBF59_RS25280	COG0113	porphobilinogen synthase activity
FBF59_RS25290	COG1388	LysM domain
FBF59_RS25305	COG0285	dihydrofolate synthase activity
FBF59_RS25325	COG1077	Cell shape determining protein MreB Mrl
FBF59_RS25345	COG2894	cell division
FBF59_RS25350	COG0739	heme binding
FBF59_RS25355	COG1994	Peptidase M50
FBF59_RS25360	COG1530	ribonuclease E activity
FBF59_RS25370	COG2868	ribosomal protein
FBF59_RS25380	COG3290	protein histidine kinase activity
FBF59_RS25390	COG0745	RESPONSE REGULATOR receiver
FBF59_RS25395	COG5002	protein histidine kinase activity
FBF59_RS25400	COG1136	(ABC) transporter
FBF59_RS25405	COG0577	efflux transmembrane transporter activity
FBF59_RS25410	COG0577	efflux transmembrane transporter activity
FBF59_RS25415	COG0077	Prephenate dehydratase
FBF59_RS25425	COG2258	MOSC domain
FBF59_RS25430	COG1827	regulation of RNA biosynthetic process
FBF59_RS25435	COG1104	cysteine desulfurase activity
FBF59_RS25440	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FBF59_RS25445	COG0157	Belongs to the NadC ModD family
FBF59_RS25475	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FBF59_RS25505	COG1862	Preprotein translocase
FBF59_RS25515	COG2323	membrane
FBF59_RS25520	COG2244	polysaccharide biosynthetic process
FBF59_RS25530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FBF59_RS25530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FBF59_RS25535	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FBF59_RS25540	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FBF59_RS25540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FBF59_RS25550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FBF59_RS25580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FBF59_RS25595	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FBF59_RS25600	COG1959	2 iron, 2 sulfur cluster binding
FBF59_RS25605	COG1104	cysteine desulfurase activity
FBF59_RS25620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FBF59_RS25640	COG0628	permease
FBF59_RS25655	COG4472	Bacterial protein of unknown function (DUF965)
FBF59_RS25670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FBF59_RS25675	COG4122	O-methyltransferase activity
FBF59_RS25680	COG0826	peptidase U32
FBF59_RS25685	COG0826	peptidase U32
FBF59_RS25705	COG0768	penicillin binding
FBF59_RS25730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FBF59_RS25735	COG0626	cystathionine gamma-synthase activity
FBF59_RS25740	COG1454	alcohol dehydrogenase
FBF59_RS25740	COG1012	belongs to the aldehyde dehydrogenase family
FBF59_RS25755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FBF59_RS25795	COG2259	Doxx family
FBF59_RS25800	COG2514	catechol 2,3-dioxygenase activity
FBF59_RS25810	COG3186	Phenylalanine-4-hydroxylase
FBF59_RS25815	COG1404	Belongs to the peptidase S8 family
FBF59_RS25850	COG2267	carboxylic ester hydrolase activity
FBF59_RS25860	COG1785	Belongs to the alkaline phosphatase family
FBF59_RS25870	COG2357	RelA SpoT domain protein
FBF59_RS25875	COG0778	Nitroreductase
FBF59_RS25885	COG1595	DNA-templated transcription, initiation
FBF59_RS25910	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FBF59_RS25915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FBF59_RS25925	COG1534	Rna-binding protein
FBF59_RS25935	COG1713	HD superfamily hydrolase involved in NAD metabolism
FBF59_RS25940	COG0799	negative regulation of ribosome biogenesis
FBF59_RS25945	COG2226	methyltransferase
FBF59_RS25950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FBF59_RS25955	COG1555	photosystem II stabilization
FBF59_RS25955	COG1596	polysaccharide export
FBF59_RS25960	COG2131	deaminase
FBF59_RS25965	COG0658	competence protein
FBF59_RS25965	COG2333	competence protein COMEC
FBF59_RS25975	COG1466	dna polymerase III delta subunit
FBF59_RS26000	COG1733	regulation of RNA biosynthetic process
FBF59_RS26005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FBF59_RS26035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FBF59_RS26040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FBF59_RS26045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FBF59_RS26050	COG1610	YqeY-like protein
FBF59_RS26070	COG1702	phosphate starvation-inducible protein PhoH
FBF59_RS26075	COG1480	7TM receptor with intracellular HD hydrolase
FBF59_RS26085	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FBF59_RS26090	COG0295	cytidine deaminase activity
FBF59_RS26095	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FBF59_RS26110	COG0517	IMP dehydrogenase activity
FBF59_RS26120	COG0358	DNA primase activity
FBF59_RS26125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FBF59_RS26135	COG2384	SAM-dependent methyltransferase
FBF59_RS26140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FBF59_RS26170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FBF59_RS26175	COG1121	(ABC) transporter
FBF59_RS26180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FBF59_RS26185	COG0735	belongs to the Fur family
FBF59_RS26200	COG5521	maltodextrose utilization protein MalA
FBF59_RS26210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FBF59_RS26215	COG0477	Major facilitator Superfamily
FBF59_RS26220	COG0582	viral genome integration into host DNA
FBF59_RS26240	COG1396	sequence-specific DNA binding
FBF59_RS26315	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FBF59_RS26410	COG5632	N-Acetylmuramoyl-L-alanine amidase
FBF59_RS26410	COG3409	Peptidoglycan-binding domain 1 protein
FBF59_RS26410	COG1388	LysM domain
FBF59_RS26450	COG0768	penicillin binding
FBF59_RS26460	COG0573	inorganic phosphate transmembrane transporter activity
FBF59_RS26465	COG0573	inorganic phosphate transmembrane transporter activity
FBF59_RS26475	COG0704	Plays a role in the regulation of phosphate uptake
FBF59_RS26480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FBF59_RS26485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FBF59_RS26490	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FBF59_RS26495	COG4483	Protein conserved in bacteria
FBF59_RS26500	COG1940	carbohydrate kinase activity
FBF59_RS26510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FBF59_RS26530	COG0626	cystathionine gamma-synthase activity
FBF59_RS26535	COG0626	cystathionine gamma-synthase activity
FBF59_RS26540	COG0646	methionine synthase
FBF59_RS26540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FBF59_RS26545	COG0646	methionine synthase
FBF59_RS26545	COG1410	methionine synthase
FBF59_RS26600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FBF59_RS26605	COG1459	type II secretion system
FBF59_RS26640	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FBF59_RS26670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FBF59_RS26715	COG2076	Multidrug Resistance protein
FBF59_RS26720	COG2076	Multidrug Resistance protein
FBF59_RS26730	COG1609	Transcriptional regulator
FBF59_RS26740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FBF59_RS26775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FBF59_RS26785	COG3872	metal-dependent enzyme
FBF59_RS26800	COG0006	proline dipeptidase activity
FBF59_RS26825	COG3854	ATPases associated with a variety of cellular activities
FBF59_RS26870	COG0511	ligase activity, forming carbon-carbon bonds
FBF59_RS26875	COG0439	Biotin carboxylase
FBF59_RS26880	COG1302	Protein conserved in bacteria
FBF59_RS26905	COG0142	geranyltranstransferase activity
FBF59_RS26915	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FBF59_RS26925	COG0497	DNA recombination
FBF59_RS26930	COG0750	zinc metalloprotease
FBF59_RS26980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FBF59_RS27025	COG3093	addiction module antidote protein HigA
FBF59_RS27030	COG0584	glycerophosphoryl diester phosphodiesterase
FBF59_RS27040	COG3290	protein histidine kinase activity
FBF59_RS27040	COG3829	transcription factor binding
FBF59_RS27050	COG0280	phosphate acetyltransferase
FBF59_RS27065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FBF59_RS27070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FBF59_RS27075	COG0022	dehydrogenase e1 component
FBF59_RS27080	COG0508	dehydrogenase complex catalyzes the overall conversion of
FBF59_RS27090	COG0772	Belongs to the SEDS family
FBF59_RS27095	COG2323	membrane
FBF59_RS27115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FBF59_RS27120	COG0765	amino acid transport
FBF59_RS27125	COG1126	abc transporter atp-binding protein
FBF59_RS27130	COG4129	membrane
FBF59_RS27135	COG1376	ErfK ybiS ycfS ynhG family protein
FBF59_RS27145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FBF59_RS27150	COG2195	Cleaves the N-terminal amino acid of tripeptides
FBF59_RS27160	COG1285	pathogenesis
FBF59_RS27190	COG1760	l-serine dehydratase
FBF59_RS27195	COG1760	l-serine dehydratase
FBF59_RS27200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FBF59_RS27205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FBF59_RS27210	COG0300	oxidoreductase activity
FBF59_RS27255	COG1522	sequence-specific DNA binding
FBF59_RS27265	COG0737	Belongs to the 5'-nucleotidase family
FBF59_RS27270	COG1757	Na H antiporter
FBF59_RS27280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FBF59_RS27295	COG2226	methyltransferase
FBF59_RS27295	COG1073	alpha beta
FBF59_RS27325	COG0307	riboflavin synthase, alpha
FBF59_RS27330	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FBF59_RS27330	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FBF59_RS27345	COG1073	alpha beta
FBF59_RS27350	COG0456	acetyltransferase
FBF59_RS27355	COG1609	Transcriptional regulator
FBF59_RS27360	COG2056	Na+-H+ antiporter family
FBF59_RS27365	COG0596	Alpha beta hydrolase
FBF59_RS27375	COG4085	toxin activity
FBF59_RS27375	COG1525	nuclease
FBF59_RS27375	COG0737	Belongs to the 5'-nucleotidase family
FBF59_RS27385	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FBF59_RS27385	COG0456	acetyltransferase
FBF59_RS27390	COG0656	L-ascorbic acid biosynthetic process
FBF59_RS27395	COG0667	Aldo Keto reductase
FBF59_RS27415	COG1300	Membrane
FBF59_RS27420	COG0735	belongs to the Fur family
FBF59_RS27430	COG4974	Belongs to the 'phage' integrase family
FBF59_RS27455	COG0598	Magnesium transport protein CorA
FBF59_RS27470	COG1846	Transcriptional regulator
FBF59_RS27490	COG1131	(ABC) transporter
FBF59_RS27495	COG1725	Transcriptional regulator
FBF59_RS27505	COG1686	Belongs to the peptidase S11 family
FBF59_RS27525	COG0733	neurotransmitter:sodium symporter activity
FBF59_RS27550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FBF59_RS27565	COG0697	spore germination
FBF59_RS27570	COG0561	phosphatase activity
FBF59_RS27575	COG4086	secreted protein
FBF59_RS27580	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FBF59_RS27585	COG0456	acetyltransferase
FBF59_RS27590	COG1547	Domain of unknown function (DUF309)
FBF59_RS27620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FBF59_RS27630	COG2188	Transcriptional regulator
FBF59_RS27640	COG3711	transcriptional antiterminator
FBF59_RS27645	COG2190	(PTS) system
FBF59_RS27645	COG1263	PTS System
FBF59_RS27645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FBF59_RS27670	COG0778	Nitroreductase
FBF59_RS27675	COG2199	diguanylate cyclase activity
FBF59_RS27685	COG2084	Dehydrogenase
FBF59_RS27720	COG0436	Aminotransferase
FBF59_RS27725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FBF59_RS27745	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS27750	COG1695	Transcriptional regulator
FBF59_RS27785	COG0183	Belongs to the thiolase family
FBF59_RS27825	COG3842	ATPase activity
FBF59_RS27830	COG0366	Alpha amylase catalytic
FBF59_RS27840	COG2182	Extracellular solute-binding protein
FBF59_RS27845	COG1175	transmembrane transport
FBF59_RS27850	COG3833	ABC-type maltose transport systems, permease component
FBF59_RS27855	COG1609	Transcriptional regulator
FBF59_RS27860	COG0436	Aminotransferase
FBF59_RS27870	COG2205	protein histidine kinase activity
FBF59_RS27880	COG3209	COG3209 Rhs family protein
FBF59_RS27900	COG2814	Major facilitator Superfamily
FBF59_RS27945	COG1408	metallophosphoesterase
FBF59_RS27950	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS27955	COG2200	EAL domain
FBF59_RS27970	COG4703	Protein of unknown function (DUF1797)
FBF59_RS27975	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FBF59_RS27985	COG0517	IMP dehydrogenase activity
FBF59_RS27990	COG0583	DNA-binding transcription factor activity
FBF59_RS28010	COG0569	domain protein
FBF59_RS28015	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FBF59_RS28030	COG0561	phosphatase activity
FBF59_RS28045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FBF59_RS28050	COG0022	dehydrogenase e1 component
FBF59_RS28100	COG1982	Orn Lys Arg decarboxylase major
FBF59_RS28120	COG0483	inositol monophosphate 1-phosphatase activity
FBF59_RS28130	COG1217	gtp-binding protein TYPA
FBF59_RS28145	COG4896	Protein conserved in bacteria
FBF59_RS28155	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FBF59_RS28160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FBF59_RS28170	COG0772	Belongs to the SEDS family
FBF59_RS28180	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FBF59_RS28215	COG3336	cytochrome c oxidase
FBF59_RS28230	COG2340	Cysteine-rich secretory protein family
FBF59_RS28245	COG0406	alpha-ribazole phosphatase activity
FBF59_RS28250	COG3679	Belongs to the UPF0342 family
FBF59_RS28265	COG0742	ribosomal rna small subunit methyltransferase
FBF59_RS28275	COG3314	Sporulation integral membrane protein YlbJ
FBF59_RS28280	COG1752	Esterase of the alpha-beta hydrolase superfamily
FBF59_RS28285	COG3480	Lon protease (S16) C-terminal proteolytic domain
FBF59_RS28295	COG1399	metal-binding, possibly nucleic acid-binding protein
FBF59_RS28300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FBF59_RS28315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FBF59_RS28335	COG0768	penicillin binding
FBF59_RS28340	COG0768	penicillin binding
FBF59_RS28360	COG0772	Belongs to the SEDS family
FBF59_RS28380	COG0849	cell division
FBF59_RS28385	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FBF59_RS28395	COG1191	sigma factor activity
FBF59_RS28400	COG1191	sigma factor activity
FBF59_RS28405	COG1873	PFAM PRC-barrel domain
FBF59_RS28415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FBF59_RS28425	COG0762	integral membrane protein
FBF59_RS28430	COG2302	S4 RNA-binding domain
FBF59_RS28435	COG3599	regulation of cell shape
FBF59_RS28455	COG0564	pseudouridine synthase activity
FBF59_RS28515	COG3069	C4-dicarboxylate transmembrane transporter activity
FBF59_RS28535	COG0006	proline dipeptidase activity
FBF59_RS28545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FBF59_RS28550	COG1561	YicC-like family, N-terminal region
FBF59_RS28570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FBF59_RS28575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FBF59_RS28590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FBF59_RS28590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FBF59_RS28600	COG0631	protein serine/threonine phosphatase activity
FBF59_RS28605	COG2815	serine threonine protein kinase
FBF59_RS28605	COG0515	serine threonine protein kinase
FBF59_RS28615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FBF59_RS28620	COG1564	THIamine pyrophosphokinase
FBF59_RS28635	COG1302	Protein conserved in bacteria
FBF59_RS28640	COG1461	Dihydroxyacetone kinase
FBF59_RS28645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FBF59_RS28660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FBF59_RS28665	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS28670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FBF59_RS28705	COG2732	(Barnase) inhibitor
FBF59_RS28770	COG2890	protein-(glutamine-N5) methyltransferase activity
FBF59_RS28800	COG0367	asparagine synthase
FBF59_RS28805	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS28820	COG0824	Thioesterase
FBF59_RS28825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FBF59_RS28830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FBF59_RS28840	COG0318	PFAM AMP-dependent synthetase and ligase
FBF59_RS28845	COG0318	PFAM AMP-dependent synthetase and ligase
FBF59_RS28945	COG1136	(ABC) transporter
FBF59_RS28950	COG0577	efflux transmembrane transporter activity
FBF59_RS28955	COG1349	DNA-binding transcription factor activity
FBF59_RS28960	COG0546	phosphoglycolate phosphatase activity
FBF59_RS28970	COG0768	penicillin binding
FBF59_RS28980	COG1595	DNA-templated transcription, initiation
FBF59_RS29015	COG0772	Belongs to the SEDS family
FBF59_RS29020	COG0741	lytic transglycosylase activity
FBF59_RS29035	COG0577	efflux transmembrane transporter activity
FBF59_RS29040	COG1136	(ABC) transporter
FBF59_RS29050	COG1278	Cold shock
FBF59_RS29065	COG1329	Transcriptional regulator
FBF59_RS29090	COG0583	DNA-binding transcription factor activity
FBF59_RS29095	COG4122	O-methyltransferase activity
FBF59_RS29100	COG2814	Major facilitator Superfamily
FBF59_RS29105	COG1309	transcriptional regulator
FBF59_RS29140	COG1131	(ABC) transporter
FBF59_RS29145	COG1725	Transcriptional regulator
FBF59_RS29160	COG0561	phosphatase activity
FBF59_RS29190	COG1349	DNA-binding transcription factor activity
FBF59_RS29305	COG3883	PFAM NLP P60 protein
FBF59_RS29305	COG0791	NLP P60 protein
FBF59_RS29450	COG1012	belongs to the aldehyde dehydrogenase family
FBF59_RS29450	COG1454	alcohol dehydrogenase
FBF59_RS29460	COG0535	radical SAM domain protein
FBF59_RS29470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FBF59_RS29470	COG1328	CTP reductase activity
FBF59_RS29485	COG0426	domain, Protein
FBF59_RS29490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FBF59_RS29495	COG1773	rubredoxin
FBF59_RS29505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FBF59_RS29520	COG4990	cell redox homeostasis
FBF59_RS29525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FBF59_RS29530	COG2116	formate transmembrane transporter activity
FBF59_RS29545	COG0531	amino acid
FBF59_RS29560	COG0531	amino acid
FBF59_RS29565	COG0657	acetylesterase activity
FBF59_RS29585	COG1404	Belongs to the peptidase S8 family
FBF59_RS29615	COG2070	2-Nitropropane dioxygenase
FBF59_RS29625	COG5002	protein histidine kinase activity
FBF59_RS29630	COG0745	RESPONSE REGULATOR receiver
FBF59_RS29635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FBF59_RS29640	COG0577	efflux transmembrane transporter activity
FBF59_RS29645	COG1136	(ABC) transporter
FBF59_RS29670	COG0823	Involved in the tonB-independent uptake of proteins
FBF59_RS29695	COG3979	chitinase
FBF59_RS29720	COG2376	Dihydroxyacetone kinase
FBF59_RS29730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FBF59_RS29735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FBF59_RS29745	COG3715	PTS system
FBF59_RS29750	COG3716	PTS system mannose fructose sorbose family IID component
FBF59_RS29760	COG5632	N-Acetylmuramoyl-L-alanine amidase
FBF59_RS29760	COG3409	Peptidoglycan-binding domain 1 protein
FBF59_RS29765	COG2329	Antibiotic biosynthesis monooxygenase
FBF59_RS29790	COG2843	Capsule synthesis protein
FBF59_RS29795	COG1876	peptidase activity
FBF59_RS29805	COG1396	sequence-specific DNA binding
FBF59_RS29810	COG3048	D-serine ammonia-lyase activity
FBF59_RS29840	COG0756	dUTP diphosphatase activity
FBF59_RS29860	COG3011	Protein conserved in bacteria
FBF59_RS29900	COG1476	TRANSCRIPTIONal
FBF59_RS29915	COG0659	secondary active sulfate transmembrane transporter activity
FBF59_RS29940	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FBF59_RS29995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FBF59_RS29995	COG4499	WXG100 protein secretion system (Wss), protein YukC
FBF59_RS30005	COG0584	glycerophosphoryl diester phosphodiesterase
FBF59_RS30015	COG3711	transcriptional antiterminator
FBF59_RS30015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FBF59_RS30020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FBF59_RS30020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FBF59_RS30020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FBF59_RS30025	COG1482	cell wall glycoprotein biosynthetic process
FBF59_RS30030	COG5002	protein histidine kinase activity
FBF59_RS30030	COG3850	Histidine kinase
FBF59_RS30035	COG0745	RESPONSE REGULATOR receiver
FBF59_RS30045	COG1136	(ABC) transporter
FBF59_RS30050	COG0577	efflux transmembrane transporter activity
FBF59_RS30060	COG0833	amino acid
FBF59_RS30065	COG2040	homocysteine
FBF59_RS30080	COG1396	sequence-specific DNA binding
FBF59_RS30085	COG3048	D-serine ammonia-lyase activity
FBF59_RS30095	COG2801	Transposase and inactivated derivatives
FBF59_RS30115	COG0667	Aldo Keto reductase
FBF59_RS30195	COG4974	Belongs to the 'phage' integrase family
FBF59_RS30205	COG2239	Acts as a magnesium transporter
FBF59_RS30210	COG0772	Belongs to the SEDS family
FBF59_RS30215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FBF59_RS30225	COG2814	Major facilitator Superfamily
FBF59_RS30230	COG1846	Transcriptional regulator
FBF59_RS30235	COG1846	Transcriptional regulator
FBF59_RS30240	COG2124	cytochrome p450
FBF59_RS30285	COG1091	dTDP-4-dehydrorhamnose reductase activity
FBF59_RS30305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FBF59_RS30310	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FBF59_RS30325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FBF59_RS30335	COG1028	Short-chain dehydrogenase reductase Sdr
FBF59_RS30350	COG0842	Transport permease protein
FBF59_RS30355	COG1131	(ABC) transporter
FBF59_RS30360	COG3754	Rhamnan synthesis protein F
FBF59_RS30580	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FBF59_RS30580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FBF59_RS30600	COG3764	Sortase (surface protein transpeptidase)
FBF59_RS30730	COG4990	cell redox homeostasis
FBF59_RS30870	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FBF59_RS31115	COG0187	DNA topoisomerase II activity
FBF59_RS31120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FBF59_RS31190	COG0358	DNA primase activity
FBF59_RS31395	COG1876	peptidase activity
FBF59_RS31535	COG4193	domain, Protein
FBF59_RS31535	COG5263	repeat protein
FBF59_RS31660	COG3409	Peptidoglycan-binding domain 1 protein
FBF59_RS31660	COG5632	N-Acetylmuramoyl-L-alanine amidase
FBF59_RS31665	COG3409	Peptidoglycan-binding domain 1 protein
FBF59_RS31665	COG5632	N-Acetylmuramoyl-L-alanine amidase
FBF59_RS31815	COG3091	SprT-like family
FBF59_RS31895	COG3481	metal-dependent phosphohydrolase, HD sub domain
FBF59_RS31970	COG2815	serine threonine protein kinase
FBF59_RS31970	COG0515	serine threonine protein kinase
FBF59_RS32380	COG0484	heat shock protein binding
FBF59_RS32485	COG0210	DNA helicase
FBF59_RS32595	COG1393	Belongs to the ArsC family
FBF59_RS32620	COG2088	sporulation resulting in formation of a cellular spore
FBF59_RS32650	COG0617	tRNA 3'-terminal CCA addition
FBF59_RS33130	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FBF59_RS33135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FBF59_RS33140	COG1780	Probably involved in ribonucleotide reductase function
FBF59_RS33145	COG4974	Belongs to the 'phage' integrase family
FBF59_RS33165	COG1404	Belongs to the peptidase S8 family
FBF59_RS33170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FBF59_RS33180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FBF59_RS33190	COG0861	Integral membrane protein TerC family
FBF59_RS33200	COG2310	stress, protein
FBF59_RS33205	COG2310	stress, protein
FBF59_RS33230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FBF59_RS33295	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FBF59_RS33415	COG1428	Deoxynucleoside kinase
FBF59_RS33435	COG5002	protein histidine kinase activity
FBF59_RS33440	COG5002	protein histidine kinase activity
FBF59_RS33455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FBF59_RS33460	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FBF59_RS33500	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FBF59_RS33505	COG0756	dUTP diphosphatase activity
FBF59_RS33530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FBF59_RS33535	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FBF59_RS33565	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FBF59_RS33575	COG0629	single-stranded DNA binding
FBF59_RS33685	COG1388	LysM domain
FBF59_RS33685	COG5632	N-Acetylmuramoyl-L-alanine amidase
FBF59_RS33685	COG3409	Peptidoglycan-binding domain 1 protein
FBF59_RS33740	COG0457	Tetratricopeptide repeat
FBF59_RS33785	COG4474	Belongs to the UPF0398 family
FBF59_RS33955	COG0860	N-Acetylmuramoyl-L-alanine amidase
FBF59_RS34010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FBF59_RS34020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FBF59_RS34025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FBF59_RS34030	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FBF59_RS34045	COG2002	toxin-antitoxin pair type II binding
FBF59_RS34050	COG1923	regulation of RNA biosynthetic process
FBF59_RS34080	COG0697	spore germination
FBF59_RS34115	COG4644	lycopene metabolic process
FBF59_RS34315	COG0577	efflux transmembrane transporter activity
FBF59_RS34320	COG1136	(ABC) transporter
FBF59_RS34345	COG3842	ATPase activity
FBF59_RS34380	COG2002	toxin-antitoxin pair type II binding
FBF59_RS34455	COG0515	serine threonine protein kinase
FBF59_RS34460	COG1132	(ABC) transporter
FBF59_RS34465	COG1695	Transcriptional regulator
FBF59_RS34520	COG1696	Membrane protein involved in D-alanine export
FBF59_RS34525	COG3209	COG3209 Rhs family protein
FBF59_RS34555	COG2070	2-Nitropropane dioxygenase
FBF59_RS34560	COG0583	DNA-binding transcription factor activity
FBF59_RS34640	COG0823	Involved in the tonB-independent uptake of proteins