locus-tag	class	description
B4918_RS00010	COG0592	DNA-directed DNA polymerase activity
B4918_RS00015	COG2501	S4 domain
B4918_RS00025	COG0187	DNA topoisomerase II activity
B4918_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B4918_RS00065	COG0516	GMP reductase activity
B4918_RS00065	COG0517	IMP dehydrogenase activity
B4918_RS00070	COG1686	Belongs to the peptidase S11 family
B4918_RS00100	COG1428	Deoxynucleoside kinase
B4918_RS00105	COG1428	Deoxynucleoside kinase
B4918_RS00110	COG1335	isochorismatase
B4918_RS00120	COG0590	tRNA wobble adenosine to inosine editing
B4918_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B4918_RS00185	COG1982	Orn Lys Arg decarboxylase major
B4918_RS00195	COG0470	DNA polymerase III
B4918_RS00200	COG1774	PSP1 C-terminal conserved region
B4918_RS00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B4918_RS00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B4918_RS00225	COG2002	toxin-antitoxin pair type II binding
B4918_RS00235	COG0084	hydrolase, TatD family'
B4918_RS00255	COG4466	Protein conserved in bacteria
B4918_RS00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B4918_RS00280	COG0251	oxidation-reduction process
B4918_RS00295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B4918_RS00310	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B4918_RS00315	COG2002	toxin-antitoxin pair type II binding
B4918_RS00320	COG2244	polysaccharide biosynthetic process
B4918_RS00325	COG3956	TIGRFAM MazG family protein
B4918_RS00330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B4918_RS00350	COG1098	S1 RNA binding domain
B4918_RS00365	COG2208	phosphoserine phosphatase activity
B4918_RS00380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B4918_RS00395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B4918_RS00400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B4918_RS00405	COG0512	Glutamine amidotransferase of anthranilate synthase
B4918_RS00410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B4918_RS00415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B4918_RS00420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B4918_RS00425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B4918_RS00430	COG1396	sequence-specific DNA binding
B4918_RS00435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B4918_RS00525	COG3880	PFAM UvrB UvrC protein
B4918_RS00535	COG0542	response to heat
B4918_RS00540	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B4918_RS00550	COG4956	integral membrane protein (PIN domain superfamily)
B4918_RS00570	COG1045	serine acetyltransferase
B4918_RS00585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B4918_RS00590	COG3688	RNA-binding protein containing a PIN domain
B4918_RS00600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B4918_RS00605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B4918_RS00610	COG0250	Participates in transcription elongation, termination and antitermination
B4918_RS00635	COG2813	Specifically methylates the guanine in position
B4918_RS00650	COG1358	cellular component organization or biogenesis
B4918_RS00760	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B4918_RS00785	COG0201	protein transport
B4918_RS00795	COG0024	Methionine aminopeptidase
B4918_RS00805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B4918_RS00840	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B4918_RS00865	COG0860	N-Acetylmuramoyl-L-alanine amidase
B4918_RS00870	COG0489	protein tyrosine kinase activity
B4918_RS00880	COG2194	sulfuric ester hydrolase activity
B4918_RS00885	COG0726	polysaccharide deacetylase
B4918_RS00975	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B4918_RS00980	COG4856	YbbR-like protein
B4918_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS01020	COG2011	ABC-type metal ion transport system permease component
B4918_RS01025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B4918_RS01030	COG1464	Belongs to the NlpA lipoprotein family
B4918_RS01035	COG0604	alcohol dehydrogenase
B4918_RS01045	COG0277	FAD linked oxidase domain protein
B4918_RS01050	COG2271	Major facilitator Superfamily
B4918_RS01060	COG2814	Major facilitator Superfamily
B4918_RS01080	COG0601	transmembrane transport
B4918_RS01085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B4918_RS01090	COG0444	Belongs to the ABC transporter superfamily
B4918_RS01095	COG4608	Belongs to the ABC transporter superfamily
B4918_RS01100	COG4166	transmembrane transport
B4918_RS01120	COG4166	transmembrane transport
B4918_RS01125	COG0656	L-ascorbic acid biosynthetic process
B4918_RS01140	COG4149	molybdate abc transporter
B4918_RS01145	COG0725	ABC transporter, periplasmic molybdate-binding protein
B4918_RS01150	COG1910	domain protein
B4918_RS01170	COG0697	spore germination
B4918_RS01185	COG0204	Acyl-transferase
B4918_RS01200	COG1609	Transcriptional regulator
B4918_RS01240	COG5298	Protein conserved in bacteria
B4918_RS01265	COG0488	(ABC) transporter
B4918_RS01280	COG0747	negative chemotaxis
B4918_RS01285	COG0601	transmembrane transport
B4918_RS01295	COG0444	Belongs to the ABC transporter superfamily
B4918_RS01300	COG4608	Belongs to the ABC transporter superfamily
B4918_RS01305	COG0561	phosphatase activity
B4918_RS01335	COG3185	4-Hydroxyphenylpyruvate dioxygenase
B4918_RS01340	COG0179	Fumarylacetoacetate (FAA) hydrolase
B4918_RS01350	COG0531	amino acid
B4918_RS01355	COG2814	Major facilitator Superfamily
B4918_RS01365	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B4918_RS01375	COG4294	response to UV
B4918_RS01380	COG0705	Rhomboid family
B4918_RS01390	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B4918_RS01395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B4918_RS01400	COG0864	Transcriptional regulator
B4918_RS01405	COG2337	Toxic component of a toxin-antitoxin (TA) module
B4918_RS01410	COG2183	response to ionizing radiation
B4918_RS01510	COG0802	atpase or kinase
B4918_RS01515	COG1214	PFAM Peptidase M22, glycoprotease
B4918_RS01520	COG0456	acetyltransferase
B4918_RS01535	COG0488	(ABC) transporter
B4918_RS01550	COG1266	CAAX protease self-immunity
B4918_RS01570	COG2252	PERMEase
B4918_RS01580	COG5002	protein histidine kinase activity
B4918_RS01610	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B4918_RS01630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4918_RS01655	COG0697	spore germination
B4918_RS01685	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B4918_RS01690	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B4918_RS01695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B4918_RS01705	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B4918_RS01720	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B4918_RS01730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B4918_RS01740	COG0151	Belongs to the GarS family
B4918_RS01765	COG0210	DNA helicase
B4918_RS01775	COG4851	CamS sex pheromone cAM373 precursor
B4918_RS01790	COG1335	isochorismatase
B4918_RS01800	COG2011	ABC-type metal ion transport system permease component
B4918_RS01805	COG1464	Belongs to the NlpA lipoprotein family
B4918_RS01810	COG4682	membrane
B4918_RS01830	COG1597	lipid kinase activity
B4918_RS01840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B4918_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
B4918_RS01855	COG2076	Multidrug Resistance protein
B4918_RS01865	COG2309	aminopeptidase activity
B4918_RS01880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B4918_RS01890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B4918_RS01895	COG4807	Protein conserved in bacteria
B4918_RS01930	COG1473	amidohydrolase
B4918_RS01945	COG0450	alkyl hydroperoxide reductase
B4918_RS01950	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
B4918_RS01960	COG0235	Class ii aldolase
B4918_RS01965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4918_RS01970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4918_RS01975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4918_RS02000	COG0166	Belongs to the GPI family
B4918_RS02030	COG5002	protein histidine kinase activity
B4918_RS02050	COG3541	Predicted nucleotidyltransferase
B4918_RS02055	COG2814	Major facilitator Superfamily
B4918_RS02060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B4918_RS02060	COG0723	plastoquinol--plastocyanin reductase activity
B4918_RS02070	COG0765	amino acid transport
B4918_RS02075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B4918_RS02080	COG1126	abc transporter atp-binding protein
B4918_RS02085	COG0840	transmembrane signaling receptor activity
B4918_RS02110	COG0549	Belongs to the carbamate kinase family
B4918_RS02115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B4918_RS02125	COG0277	FAD linked oxidase domain protein
B4918_RS02130	COG0366	Alpha amylase catalytic
B4918_RS02135	COG1263	PTS System
B4918_RS02135	COG2190	(PTS) system
B4918_RS02135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4918_RS02165	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B4918_RS02185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B4918_RS02190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B4918_RS02195	COG1116	anion transmembrane transporter activity
B4918_RS02200	COG0488	(ABC) transporter
B4918_RS02250	COG2270	Major facilitator Superfamily
B4918_RS02280	COG2310	stress, protein
B4918_RS02285	COG2310	stress, protein
B4918_RS02290	COG2310	stress, protein
B4918_RS02295	COG0861	Integral membrane protein TerC family
B4918_RS02305	COG3853	Toxic anion resistance protein (TelA)
B4918_RS02320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B4918_RS02330	COG1295	ribonuclease BN
B4918_RS02340	COG2217	Heavy metal translocating P-type atpase
B4918_RS02345	COG0697	spore germination
B4918_RS02365	COG0586	Pfam SNARE associated Golgi protein
B4918_RS02385	COG0387	Pfam Sodium calcium exchanger
B4918_RS02395	COG0535	radical SAM domain protein
B4918_RS02415	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B4918_RS02420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B4918_RS02445	COG3829	transcription factor binding
B4918_RS02455	COG0833	amino acid
B4918_RS02460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B4918_RS02490	COG2066	Belongs to the glutaminase family
B4918_RS02500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4918_RS02500	COG1263	PTS System
B4918_RS02510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B4918_RS02525	COG1216	Glycosyl transferase, family 2
B4918_RS02535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B4918_RS02535	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B4918_RS02540	COG0463	Glycosyl transferase, family 2
B4918_RS02555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B4918_RS02575	COG1228	amidohydrolase
B4918_RS02580	COG1090	epimerase
B4918_RS02610	COG1988	membrane-bound metal-dependent
B4918_RS02615	COG1194	a g-specific adenine glycosylase
B4918_RS02640	COG1132	(ABC) transporter
B4918_RS02645	COG4129	membrane
B4918_RS02650	COG0070	glutamate synthase
B4918_RS02650	COG0067	glutamate synthase
B4918_RS02650	COG0069	glutamate synthase activity
B4918_RS02660	COG4555	ABC transporter
B4918_RS02680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B4918_RS02685	COG0735	belongs to the Fur family
B4918_RS02840	COG4974	Belongs to the 'phage' integrase family
B4918_RS02875	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B4918_RS02900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B4918_RS02915	COG2766	serine protein kinase
B4918_RS02935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B4918_RS02945	COG1585	Membrane protein implicated in regulation of membrane protease activity
B4918_RS02950	COG2268	Band 7 protein
B4918_RS02960	COG3290	protein histidine kinase activity
B4918_RS02965	COG4565	transcriptional regulatory protein
B4918_RS02970	COG2851	Citrate transporter
B4918_RS02995	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
B4918_RS03000	COG3842	ATPase activity
B4918_RS03005	COG1175	transmembrane transport
B4918_RS03010	COG0395	ABC-type sugar transport system, permease component
B4918_RS03020	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B4918_RS03025	COG0745	RESPONSE REGULATOR receiver
B4918_RS03030	COG5002	protein histidine kinase activity
B4918_RS03040	COG4990	cell redox homeostasis
B4918_RS03050	COG3290	protein histidine kinase activity
B4918_RS03055	COG4565	transcriptional regulatory protein
B4918_RS03060	COG3493	citrate carrier protein
B4918_RS03065	COG0281	malic enzyme
B4918_RS03080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4918_RS03090	COG5002	protein histidine kinase activity
B4918_RS03120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B4918_RS03125	COG3383	formate dehydrogenase (NAD+) activity
B4918_RS03130	COG2427	Protein of unknown function (DUF1641)
B4918_RS03145	COG0531	amino acid
B4918_RS03150	COG0640	Transcriptional regulator
B4918_RS03155	COG2217	Heavy metal translocating P-type atpase
B4918_RS03160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B4918_RS03175	COG3227	Zinc metalloprotease (Elastase)
B4918_RS03195	COG2720	vancomycin resistance protein
B4918_RS03200	COG1316	TRANSCRIPTIONal
B4918_RS03205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B4918_RS03210	COG0346	lactoylglutathione lyase activity
B4918_RS03215	COG3547	Transposase (IS116 IS110 IS902 family)
B4918_RS03225	COG1253	flavin adenine dinucleotide binding
B4918_RS03230	COG1027	Aspartate ammonia-lyase
B4918_RS03235	COG1620	l-lactate permease
B4918_RS03250	COG3104	oligopeptide transport
B4918_RS03255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4918_RS03260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4918_RS03265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4918_RS03280	COG0156	8-amino-7-oxononanoate synthase activity
B4918_RS03285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B4918_RS03295	COG4548	von Willebrand factor, type A
B4918_RS03300	COG0714	Associated with various cellular activities
B4918_RS03320	COG0531	amino acid
B4918_RS03325	COG2188	Transcriptional regulator
B4918_RS03330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4918_RS03330	COG1263	PTS System
B4918_RS03335	COG0366	Alpha amylase catalytic
B4918_RS03350	COG0697	spore germination
B4918_RS03355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B4918_RS03360	COG1115	amino acid carrier protein
B4918_RS03370	COG1126	abc transporter atp-binding protein
B4918_RS03375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B4918_RS03380	COG0765	amino acid transport
B4918_RS03385	COG0765	amino acid transport
B4918_RS03390	COG0833	amino acid
B4918_RS03405	COG1595	DNA-templated transcription, initiation
B4918_RS03415	COG2378	regulation of single-species biofilm formation
B4918_RS03420	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B4918_RS03425	COG5002	protein histidine kinase activity
B4918_RS03440	COG0659	secondary active sulfate transmembrane transporter activity
B4918_RS03455	COG2271	Major facilitator Superfamily
B4918_RS03460	COG1846	Transcriptional regulator
B4918_RS03465	COG0477	Major facilitator Superfamily
B4918_RS03470	COG1609	Transcriptional regulator
B4918_RS03475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B4918_RS03490	COG1172	Belongs to the binding-protein-dependent transport system permease family
B4918_RS03495	COG1879	ABC-type sugar transport system periplasmic component
B4918_RS03500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B4918_RS03525	COG1063	alcohol dehydrogenase
B4918_RS03575	COG0840	transmembrane signaling receptor activity
B4918_RS03580	COG3584	3D domain protein
B4918_RS03580	COG3583	domain protein
B4918_RS03585	COG1476	TRANSCRIPTIONal
B4918_RS03605	COG3104	oligopeptide transport
B4918_RS03610	COG1114	Component of the transport system for branched-chain amino acids
B4918_RS03625	COG1113	amino acid transport
B4918_RS03630	COG2252	PERMEase
B4918_RS03645	COG2153	protein acetylation
B4918_RS03655	COG0475	glutathione-regulated potassium exporter activity
B4918_RS03655	COG0569	domain protein
B4918_RS03670	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B4918_RS03675	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B4918_RS03680	COG0833	amino acid
B4918_RS03685	COG4990	cell redox homeostasis
B4918_RS03700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B4918_RS03705	COG0697	spore germination
B4918_RS03710	COG0531	amino acid
B4918_RS03725	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B4918_RS03730	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B4918_RS03735	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B4918_RS03735	COG1918	ferrous iron import across plasma membrane
B4918_RS03740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B4918_RS03745	COG0573	inorganic phosphate transmembrane transporter activity
B4918_RS03750	COG0581	inorganic phosphate transmembrane transporter activity
B4918_RS03760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B4918_RS03880	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
B4918_RS03905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B4918_RS03910	COG1116	anion transmembrane transporter activity
B4918_RS03915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B4918_RS03920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B4918_RS03925	COG0352	thiamine-phosphate diphosphorylase activity
B4918_RS03930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B4918_RS03935	COG2104	thiamine diphosphate biosynthetic process
B4918_RS03945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B4918_RS03950	COG0351	phosphomethylpyrimidine kinase
B4918_RS03990	COG2205	protein histidine kinase activity
B4918_RS03995	COG2814	Major facilitator Superfamily
B4918_RS04000	COG1846	Transcriptional regulator
B4918_RS04025	COG1136	(ABC) transporter
B4918_RS04035	COG2252	PERMEase
B4918_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS04100	COG0778	Nitroreductase
B4918_RS04105	COG2719	SpoVR family
B4918_RS04125	COG1937	Protein conserved in bacteria
B4918_RS04130	COG0425	Belongs to the sulfur carrier protein TusA family
B4918_RS04130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B4918_RS04135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4918_RS04135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B4918_RS04140	COG0425	Belongs to the sulfur carrier protein TusA family
B4918_RS04145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B4918_RS04145	COG0425	Belongs to the sulfur carrier protein TusA family
B4918_RS04150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B4918_RS04155	COG2210	Belongs to the sulfur carrier protein TusA family
B4918_RS04160	COG0730	response to heat
B4918_RS04170	COG1316	TRANSCRIPTIONal
B4918_RS04175	COG0604	alcohol dehydrogenase
B4918_RS04180	COG1283	sodium-dependent phosphate transmembrane transporter activity
B4918_RS04195	COG3711	transcriptional antiterminator
B4918_RS04195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B4918_RS04200	COG1447	Phosphotransferase system cellobiose-specific component IIA
B4918_RS04205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B4918_RS04230	COG3584	3D domain protein
B4918_RS04230	COG1388	LysM domain
B4918_RS04235	COG0577	efflux transmembrane transporter activity
B4918_RS04240	COG1136	(ABC) transporter
B4918_RS04250	COG5522	Integral membrane protein (intg_mem_TP0381)
B4918_RS04265	COG1114	Component of the transport system for branched-chain amino acids
B4918_RS04270	COG3546	catalase activity
B4918_RS04305	COG0586	Pfam SNARE associated Golgi protein
B4918_RS04340	COG0531	amino acid
B4918_RS04345	COG0475	glutathione-regulated potassium exporter activity
B4918_RS04355	COG1737	Transcriptional regulator
B4918_RS04365	COG1263	PTS System
B4918_RS04365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4918_RS04375	COG2259	Doxx family
B4918_RS04395	COG1522	sequence-specific DNA binding
B4918_RS04405	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS04410	COG0789	Transcriptional regulator
B4918_RS04415	COG2076	Multidrug Resistance protein
B4918_RS04425	COG1309	transcriptional regulator
B4918_RS04430	COG2814	Major facilitator Superfamily
B4918_RS04435	COG1733	regulation of RNA biosynthetic process
B4918_RS04455	COG0693	protein deglycase activity
B4918_RS04460	COG0693	protein deglycase activity
B4918_RS04460	COG0753	catalase activity
B4918_RS04470	COG0531	amino acid
B4918_RS04475	COG1012	belongs to the aldehyde dehydrogenase family
B4918_RS04490	COG1132	(ABC) transporter
B4918_RS04495	COG1132	(ABC) transporter
B4918_RS04505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B4918_RS04510	COG0765	amino acid transport
B4918_RS04515	COG1126	abc transporter atp-binding protein
B4918_RS04530	COG0189	ligase activity
B4918_RS04560	COG0028	Belongs to the TPP enzyme family
B4918_RS04565	COG3527	Alpha-acetolactate decarboxylase
B4918_RS04575	COG0561	phosphatase activity
B4918_RS04590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B4918_RS04595	COG0318	PFAM AMP-dependent synthetase and ligase
B4918_RS04605	COG0659	secondary active sulfate transmembrane transporter activity
B4918_RS04610	COG2244	polysaccharide biosynthetic process
B4918_RS04630	COG1024	Enoyl-CoA hydratase
B4918_RS04650	COG1363	Peptidase, m42
B4918_RS04685	COG0601	transmembrane transport
B4918_RS04690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B4918_RS04695	COG0444	Belongs to the ABC transporter superfamily
B4918_RS04700	COG4608	Belongs to the ABC transporter superfamily
B4918_RS04730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4918_RS04750	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B4918_RS04765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B4918_RS04770	COG2814	Major facilitator Superfamily
B4918_RS04810	COG0477	Major facilitator Superfamily
B4918_RS04815	COG3290	protein histidine kinase activity
B4918_RS04820	COG4565	transcriptional regulatory protein
B4918_RS04825	COG3181	Tripartite tricarboxylate transporter family receptor
B4918_RS04860	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
B4918_RS04870	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B4918_RS04880	COG0210	DNA helicase
B4918_RS04885	COG0210	DNA helicase
B4918_RS04905	COG0642	Histidine kinase
B4918_RS04920	COG0270	DNA (cytosine-5-)-methyltransferase activity
B4918_RS04930	COG0305	Participates in initiation and elongation during chromosome replication
B4918_RS04960	COG0477	Major facilitator Superfamily
B4918_RS04980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4918_RS05030	COG1073	alpha beta
B4918_RS05100	COG1183	phosphatidylcholine synthase activity
B4918_RS05110	COG2814	Major facilitator Superfamily
B4918_RS05115	COG0640	Transcriptional regulator
B4918_RS05130	COG2376	Dihydroxyacetone kinase
B4918_RS05140	COG2376	Dihydroxyacetone kinase
B4918_RS05185	COG2373	Large extracellular alpha-helical protein
B4918_RS05255	COG1191	sigma factor activity
B4918_RS05265	COG2208	phosphoserine phosphatase activity
B4918_RS05270	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B4918_RS05320	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
B4918_RS05340	COG0420	3'-5' exonuclease activity
B4918_RS05345	COG4717	serine-type aminopeptidase activity
B4918_RS05365	COG1280	lysine exporter protein (LysE YggA)
B4918_RS05370	COG0346	lactoylglutathione lyase activity
B4918_RS05375	COG0346	lactoylglutathione lyase activity
B4918_RS05380	COG0457	Tetratricopeptide repeat
B4918_RS05390	COG2267	carboxylic ester hydrolase activity
B4918_RS05405	COG2140	Oxalate decarboxylase
B4918_RS05410	COG3620	sequence-specific DNA binding
B4918_RS05415	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
B4918_RS05420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B4918_RS05430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B4918_RS05455	COG3973	AAA domain
B4918_RS05485	COG4980	gas vesicle protein
B4918_RS05490	COG0537	adenosine 5'-monophosphoramidase activity
B4918_RS05500	COG1131	(ABC) transporter
B4918_RS05505	COG4473	ABC transporter
B4918_RS05515	COG1309	transcriptional regulator
B4918_RS05525	COG3402	PFAM membrane-flanked domain
B4918_RS05530	COG3428	Bacterial PH domain
B4918_RS05565	COG0697	spore germination
B4918_RS05570	COG3402	PFAM membrane-flanked domain
B4918_RS05575	COG3428	Bacterial PH domain
B4918_RS05580	COG2329	Antibiotic biosynthesis monooxygenase
B4918_RS05585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B4918_RS05625	COG1309	transcriptional regulator
B4918_RS05630	COG1511	domain protein
B4918_RS05655	COG1609	Transcriptional regulator
B4918_RS05665	COG1234	tRNA 3'-trailer cleavage
B4918_RS05670	COG0095	Lipoate-protein ligase
B4918_RS05680	COG0318	PFAM AMP-dependent synthetase and ligase
B4918_RS05720	COG1073	alpha beta
B4918_RS05725	COG1408	metallophosphoesterase
B4918_RS05730	COG1078	dGTPase activity
B4918_RS05745	COG1595	DNA-templated transcription, initiation
B4918_RS05750	COG2207	Transcriptional regulator
B4918_RS05750	COG3708	Transcriptional regulator
B4918_RS05765	COG2205	protein histidine kinase activity
B4918_RS05770	COG0745	RESPONSE REGULATOR receiver
B4918_RS05790	COG0501	Belongs to the peptidase M48B family
B4918_RS05795	COG0840	transmembrane signaling receptor activity
B4918_RS05805	COG3693	PFAM glycoside hydrolase, family 10
B4918_RS05815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B4918_RS05820	COG2224	Isocitrate lyase
B4918_RS05835	COG1278	Cold shock
B4918_RS05850	COG4903	ComK protein
B4918_RS05855	COG0398	Pfam SNARE associated Golgi protein
B4918_RS05915	COG0179	Fumarylacetoacetate (FAA) hydrolase
B4918_RS05940	COG0367	asparagine synthase
B4918_RS06160	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4918_RS06195	COG0753	catalase activity
B4918_RS06200	COG0004	ammonium transporteR
B4918_RS06220	COG2996	Protein conserved in bacteria
B4918_RS06235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4918_RS06250	COG0561	phosphatase activity
B4918_RS06275	COG2267	carboxylic ester hydrolase activity
B4918_RS06290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B4918_RS06295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B4918_RS06300	COG5504	Zn-dependent protease
B4918_RS06315	COG0180	Tryptophanyl-tRNA synthetase
B4918_RS06330	COG4166	transmembrane transport
B4918_RS06335	COG0601	transmembrane transport
B4918_RS06340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B4918_RS06345	COG0444	Belongs to the ABC transporter superfamily
B4918_RS06350	COG4608	Belongs to the ABC transporter superfamily
B4918_RS06355	COG0534	Mate efflux family protein
B4918_RS06360	COG4166	transmembrane transport
B4918_RS06380	COG1393	Belongs to the ArsC family
B4918_RS06385	COG0861	Integral membrane protein TerC family
B4918_RS06395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B4918_RS06405	COG1164	Oligoendopeptidase f
B4918_RS06420	COG2346	COG2346, Truncated hemoglobins
B4918_RS06425	COG4116	CYTH
B4918_RS06435	COG2357	RelA SpoT domain protein
B4918_RS06445	COG0564	pseudouridine synthase activity
B4918_RS06460	COG0772	Belongs to the SEDS family
B4918_RS06465	COG1216	Glycosyl transferase, family 2
B4918_RS06485	COG0463	Glycosyl transferase, family 2
B4918_RS06485	COG0457	Tetratricopeptide repeat
B4918_RS06505	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B4918_RS06520	COG1091	dTDP-4-dehydrorhamnose reductase activity
B4918_RS06565	COG2153	protein acetylation
B4918_RS06575	COG2382	esterase
B4918_RS06590	COG5492	domain, Protein
B4918_RS06595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B4918_RS06610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B4918_RS06610	COG0512	Glutamine amidotransferase of anthranilate synthase
B4918_RS06645	COG1620	l-lactate permease
B4918_RS06655	COG5634	Uncharacterized conserved protein (DUF2278)
B4918_RS06715	COG0508	dehydrogenase complex catalyzes the overall conversion of
B4918_RS06725	COG1476	TRANSCRIPTIONal
B4918_RS06770	COG2226	methyltransferase
B4918_RS06780	COG1686	Belongs to the peptidase S11 family
B4918_RS06785	COG0681	Belongs to the peptidase S26 family
B4918_RS06815	COG1012	belongs to the aldehyde dehydrogenase family
B4918_RS06825	COG1176	ABC-type spermidine putrescine transport system, permease component I
B4918_RS06830	COG1177	transmembrane transport
B4918_RS06835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B4918_RS06840	COG0671	phosphoesterase, PA-phosphatase related
B4918_RS06845	COG2409	Drug exporters of the RND superfamily
B4918_RS06855	COG0564	pseudouridine synthase activity
B4918_RS06865	COG2340	Cysteine-rich secretory protein family
B4918_RS06870	COG0247	lactate metabolic process
B4918_RS06875	COG0277	FAD linked oxidase domain protein
B4918_RS06880	COG3835	regulator
B4918_RS06890	COG0745	RESPONSE REGULATOR receiver
B4918_RS06895	COG5002	protein histidine kinase activity
B4918_RS06900	COG2186	Transcriptional regulator
B4918_RS06920	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B4918_RS06930	COG2116	formate transmembrane transporter activity
B4918_RS06935	COG0861	Integral membrane protein TerC family
B4918_RS06940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B4918_RS06950	COG2030	dehydratase
B4918_RS06970	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS06975	COG3243	poly(R)-hydroxyalkanoic acid synthase
B4918_RS06985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B4918_RS07005	COG1840	ABC-type Fe3 transport system, periplasmic component
B4918_RS07010	COG3842	ATPase activity
B4918_RS07035	COG1349	DNA-binding transcription factor activity
B4918_RS07050	COG0235	Class ii aldolase
B4918_RS07060	COG2861	carbohydrate metabolic process
B4918_RS07070	COG3852	Histidine kinase
B4918_RS07075	COG1846	Transcriptional regulator
B4918_RS07085	COG2318	DinB family
B4918_RS07095	COG5002	protein histidine kinase activity
B4918_RS07105	COG0720	synthase
B4918_RS07120	COG4873	Protein conserved in bacteria
B4918_RS07160	COG1780	Probably involved in ribonucleotide reductase function
B4918_RS07165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B4918_RS07170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B4918_RS07175	COG1725	Transcriptional regulator
B4918_RS07180	COG1131	(ABC) transporter
B4918_RS07190	COG1131	(ABC) transporter
B4918_RS07195	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B4918_RS07210	COG1522	sequence-specific DNA binding
B4918_RS07220	COG1335	isochorismatase
B4918_RS07230	COG1619	proteins homologs of microcin C7 resistance protein MccF
B4918_RS07235	COG2070	2-Nitropropane dioxygenase
B4918_RS07240	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
B4918_RS07250	COG1696	Membrane protein involved in D-alanine export
B4918_RS07275	COG0716	FMN binding
B4918_RS07335	COG1846	Transcriptional regulator
B4918_RS07345	COG1301	dicarboxylic acid transport
B4918_RS07350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B4918_RS07355	COG4709	membrane
B4918_RS07360	COG3874	Sporulation protein YtfJ
B4918_RS07390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B4918_RS07395	COG0028	Belongs to the TPP enzyme family
B4918_RS07400	COG0440	acetolactate synthase activity
B4918_RS07475	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B4918_RS07490	COG1183	phosphatidylcholine synthase activity
B4918_RS07495	COG1368	sulfuric ester hydrolase activity
B4918_RS07500	COG0582	viral genome integration into host DNA
B4918_RS07515	COG1396	sequence-specific DNA binding
B4918_RS07525	COG3645	SOS response
B4918_RS07525	COG3646	Phage regulatory protein
B4918_RS07570	COG2002	toxin-antitoxin pair type II binding
B4918_RS07665	COG0582	viral genome integration into host DNA
B4918_RS07710	COG1802	Transcriptional regulator
B4918_RS07710	COG4626	Terminase
B4918_RS07720	COG0740	serine-type endopeptidase activity
B4918_RS07790	COG4824	toxin secretion phage lysis holin
B4918_RS07795	COG3409	Peptidoglycan-binding domain 1 protein
B4918_RS07795	COG1388	LysM domain
B4918_RS07795	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4918_RS07815	COG0019	diaminopimelate decarboxylase activity
B4918_RS07835	COG0529	Catalyzes the synthesis of activated sulfate
B4918_RS07840	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B4918_RS07860	COG1648	precorrin-2 dehydrogenase activity
B4918_RS07870	COG0733	neurotransmitter:sodium symporter activity
B4918_RS07890	COG1757	Na H antiporter
B4918_RS07905	COG4758	membrane
B4918_RS07910	COG4585	Histidine kinase
B4918_RS07915	COG2197	response regulator
B4918_RS07925	COG1114	Component of the transport system for branched-chain amino acids
B4918_RS07980	COG0730	response to heat
B4918_RS07985	COG0306	phosphate transporter
B4918_RS07990	COG1392	Phosphate transport regulator
B4918_RS07995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B4918_RS08010	COG3852	Histidine kinase
B4918_RS08015	COG1801	Protein of unknown function DUF72
B4918_RS08025	COG0582	viral genome integration into host DNA
B4918_RS08030	COG5002	protein histidine kinase activity
B4918_RS08045	COG0392	lysyltransferase activity
B4918_RS08045	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B4918_RS08060	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B4918_RS08065	COG1686	Belongs to the peptidase S11 family
B4918_RS08070	COG2715	membrane protein required for spore maturation
B4918_RS08075	COG0700	Nucleoside recognition
B4918_RS08080	COG1187	pseudouridine synthase activity
B4918_RS08090	COG1333	cytochrome c biogenesis protein
B4918_RS08095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B4918_RS08100	COG0745	RESPONSE REGULATOR receiver
B4918_RS08105	COG5002	protein histidine kinase activity
B4918_RS08110	COG2096	Adenosyltransferase
B4918_RS08125	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B4918_RS08130	COG1141	Ferredoxin
B4918_RS08140	COG0514	ATP-dependent DNA helicase (RecQ)
B4918_RS08145	COG1266	CAAX protease self-immunity
B4918_RS08155	COG1408	metallophosphoesterase
B4918_RS08160	COG0789	Transcriptional regulator
B4918_RS08170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B4918_RS08190	COG0492	ferredoxin-NADP+ reductase activity
B4918_RS08195	COG0252	asparaginase activity
B4918_RS08265	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B4918_RS08280	COG0142	geranyltranstransferase activity
B4918_RS08290	COG0142	geranyltranstransferase activity
B4918_RS08320	COG0457	Tetratricopeptide repeat
B4918_RS08340	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B4918_RS08345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B4918_RS08345	COG2010	Cytochrome c
B4918_RS08350	COG4347	Protein of unknown function (DUF1405)
B4918_RS08365	COG2738	Putative neutral zinc metallopeptidase
B4918_RS08375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4918_RS08380	COG1694	Mazg nucleotide pyrophosphohydrolase
B4918_RS08400	COG0438	transferase activity, transferring glycosyl groups
B4918_RS08440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B4918_RS08440	COG1199	ATP-dependent helicase activity
B4918_RS08460	COG3935	DnaD domain protein
B4918_RS08465	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B4918_RS08475	COG4499	WXG100 protein secretion system (Wss), protein YukC
B4918_RS08475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B4918_RS08535	COG0116	Belongs to the methyltransferase superfamily
B4918_RS08545	COG1199	ATP-dependent helicase activity
B4918_RS08550	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B4918_RS08560	COG3173	Aminoglycoside phosphotransferase
B4918_RS08565	COG0024	Methionine aminopeptidase
B4918_RS08575	COG2233	PERMEase
B4918_RS08580	COG2311	Membrane
B4918_RS08590	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B4918_RS08600	COG0456	acetyltransferase
B4918_RS08635	COG0754	glutathionylspermidine amidase activity
B4918_RS08650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B4918_RS08675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B4918_RS08690	COG1215	transferase activity, transferring glycosyl groups
B4918_RS08695	COG0438	transferase activity, transferring glycosyl groups
B4918_RS08710	COG0454	-acetyltransferase
B4918_RS08730	COG0328	RNA-DNA hybrid ribonuclease activity
B4918_RS08765	COG3403	YqcI/YcgG family
B4918_RS08770	COG1280	lysine exporter protein (LysE YggA)
B4918_RS08790	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B4918_RS08795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B4918_RS08805	COG0475	glutathione-regulated potassium exporter activity
B4918_RS08810	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B4918_RS08815	COG0789	Transcriptional regulator
B4918_RS08815	COG4978	Transcriptional regulator
B4918_RS08825	COG2323	membrane
B4918_RS08830	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B4918_RS08865	COG1923	regulation of RNA biosynthetic process
B4918_RS08875	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B4918_RS08880	COG1360	Flagellar Motor Protein
B4918_RS08885	COG2201	protein-glutamate methylesterase activity
B4918_RS08890	COG0643	Histidine kinase
B4918_RS08890	COG2198	Histidine kinase
B4918_RS08895	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B4918_RS08895	COG1776	CheC inhibitor of MCP methylation
B4918_RS08910	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B4918_RS08930	COG1256	bacterial-type flagellum assembly
B4918_RS08935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B4918_RS08960	COG1815	bacterial-type flagellum-dependent cell motility
B4918_RS08965	COG1558	bacterial-type flagellum-dependent cell motility
B4918_RS08970	COG1677	Flagellar hook-basal body complex protein FliE
B4918_RS08975	COG1766	The M ring may be actively involved in energy transduction
B4918_RS08980	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B4918_RS08990	COG1157	protein secretion by the type III secretion system
B4918_RS09010	COG1749	Flagellar hook protein flgE
B4918_RS09025	COG0784	Response regulator, receiver
B4918_RS09025	COG0835	chemotaxis
B4918_RS09035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B4918_RS09040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B4918_RS09045	COG0741	lytic transglycosylase activity
B4918_RS09055	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B4918_RS09060	COG1776	CheC inhibitor of MCP methylation
B4918_RS09060	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B4918_RS09070	COG1338	Plays a role in the flagellum-specific transport system
B4918_RS09075	COG1987	bacterial-type flagellum assembly
B4918_RS09085	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B4918_RS09090	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B4918_RS09095	COG1419	protein localization to endoplasmic reticulum
B4918_RS09100	COG4786	Flagellar basal body rod
B4918_RS09110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B4918_RS09140	COG2329	Antibiotic biosynthesis monooxygenase
B4918_RS09175	COG3842	ATPase activity
B4918_RS09185	COG1177	transmembrane transport
B4918_RS09225	COG0406	alpha-ribazole phosphatase activity
B4918_RS09240	COG1846	Transcriptional regulator
B4918_RS09250	COG0367	asparagine synthase
B4918_RS09285	COG0523	cobalamin synthesis protein
B4918_RS09295	COG0701	Predicted permease
B4918_RS09305	COG1216	Glycosyl transferase, family 2
B4918_RS09305	COG0438	transferase activity, transferring glycosyl groups
B4918_RS09310	COG1757	Na H antiporter
B4918_RS09315	COG0789	Transcriptional regulator
B4918_RS09345	COG0534	Mate efflux family protein
B4918_RS09350	COG3340	Belongs to the peptidase S51 family
B4918_RS09370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4918_RS09540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B4918_RS09600	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B4918_RS09600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B4918_RS09625	COG1484	DNA-dependent DNA replication
B4918_RS09660	COG2733	membrane
B4918_RS09700	COG1131	(ABC) transporter
B4918_RS09715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B4918_RS09720	COG0528	UMP kinase activity
B4918_RS09730	COG1027	Aspartate ammonia-lyase
B4918_RS09735	COG0281	malic enzyme
B4918_RS09740	COG4191	Histidine kinase
B4918_RS09745	COG0784	Response regulator, receiver
B4918_RS09750	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B4918_RS09810	COG2814	Major facilitator Superfamily
B4918_RS09825	COG1695	Transcriptional regulator
B4918_RS09835	COG0477	Major facilitator Superfamily
B4918_RS09845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B4918_RS09850	COG2223	nitrite transmembrane transporter activity
B4918_RS09855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B4918_RS09875	COG0733	neurotransmitter:sodium symporter activity
B4918_RS09885	COG5566	PFAM Mor transcription activator
B4918_RS09890	COG2323	membrane
B4918_RS09920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B4918_RS09930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B4918_RS09935	COG0028	Belongs to the TPP enzyme family
B4918_RS09955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B4918_RS09980	COG2814	Major facilitator Superfamily
B4918_RS09985	COG3384	dioxygenase
B4918_RS10000	COG3279	Response regulator of the LytR AlgR family
B4918_RS10005	COG0427	acetyl-CoA hydrolase
B4918_RS10025	COG4166	transmembrane transport
B4918_RS10030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4918_RS10050	COG1914	H( )-stimulated, divalent metal cation uptake system
B4918_RS10065	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B4918_RS10070	COG0531	amino acid
B4918_RS10095	COG2309	aminopeptidase activity
B4918_RS10110	COG0456	acetyltransferase
B4918_RS10130	COG1309	transcriptional regulator
B4918_RS10135	COG2390	Transcriptional regulator
B4918_RS10145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B4918_RS10150	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B4918_RS10155	COG0295	cytidine deaminase activity
B4918_RS10200	COG4846	Membrane protein involved in cytochrome C biogenesis
B4918_RS10210	COG0006	proline dipeptidase activity
B4918_RS10255	COG1595	DNA-templated transcription, initiation
B4918_RS10260	COG0726	polysaccharide deacetylase
B4918_RS10285	COG2239	Acts as a magnesium transporter
B4918_RS10290	COG0772	Belongs to the SEDS family
B4918_RS10335	COG1396	sequence-specific DNA binding
B4918_RS10345	COG1396	sequence-specific DNA binding
B4918_RS10360	COG4974	Belongs to the 'phage' integrase family
B4918_RS10380	COG0814	amino acid
B4918_RS10385	COG0697	spore germination
B4918_RS10390	COG0463	Glycosyl transferase, family 2
B4918_RS10390	COG0457	Tetratricopeptide repeat
B4918_RS10440	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B4918_RS10495	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B4918_RS10500	COG1959	2 iron, 2 sulfur cluster binding
B4918_RS10510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B4918_RS10540	COG3344	reverse transcriptase
B4918_RS10610	COG1114	Component of the transport system for branched-chain amino acids
B4918_RS10620	COG1276	copper resistance
B4918_RS10620	COG2372	response to copper ion
B4918_RS10625	COG4549	nuclear export factor GLE1
B4918_RS10630	COG0697	spore germination
B4918_RS10635	COG0583	DNA-binding transcription factor activity
B4918_RS10640	COG1959	2 iron, 2 sulfur cluster binding
B4918_RS10645	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B4918_RS10650	COG0778	Nitroreductase
B4918_RS10660	COG0154	amidase activity
B4918_RS10665	COG1396	sequence-specific DNA binding
B4918_RS10695	COG3547	Transposase (IS116 IS110 IS902 family)
B4918_RS10770	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B4918_RS10770	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B4918_RS10860	COG2002	toxin-antitoxin pair type II binding
B4918_RS11075	COG0628	permease
B4918_RS11085	COG1231	oxidoreductase activity
B4918_RS11095	COG0523	cobalamin synthesis protein
B4918_RS11105	COG0411	ABC transporter
B4918_RS11115	COG0559	Belongs to the binding-protein-dependent transport system permease family
B4918_RS11125	COG0583	DNA-binding transcription factor activity
B4918_RS11135	COG1942	4-Oxalocrotonate Tautomerase
B4918_RS11155	COG1271	oxidase subunit
B4918_RS11160	COG1294	oxidase, subunit
B4918_RS11165	COG4988	ABC transporter
B4918_RS11170	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B4918_RS11180	COG1216	Glycosyl transferase, family 2
B4918_RS11220	COG1686	Belongs to the peptidase S11 family
B4918_RS11235	COG0791	NLP P60 protein
B4918_RS11235	COG1388	LysM domain
B4918_RS11245	COG1132	(ABC) transporter
B4918_RS11250	COG0745	RESPONSE REGULATOR receiver
B4918_RS11255	COG5002	protein histidine kinase activity
B4918_RS11260	COG0300	oxidoreductase activity
B4918_RS11280	COG0726	polysaccharide deacetylase
B4918_RS11300	COG0460	homoserine dehydrogenase
B4918_RS11325	COG1316	TRANSCRIPTIONal
B4918_RS11345	COG1285	pathogenesis
B4918_RS11350	COG1247	-acetyltransferase
B4918_RS11360	COG4264	IucA IucC family
B4918_RS11365	COG0318	PFAM AMP-dependent synthetase and ligase
B4918_RS11380	COG1082	Xylose isomerase domain protein TIM barrel
B4918_RS11390	COG2814	Major facilitator Superfamily
B4918_RS11395	COG1279	arginine transmembrane transporter activity
B4918_RS11400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4918_RS11415	COG3344	reverse transcriptase
B4918_RS11460	COG0577	efflux transmembrane transporter activity
B4918_RS11465	COG2002	toxin-antitoxin pair type II binding
B4918_RS11470	COG1404	Belongs to the peptidase S8 family
B4918_RS11475	COG0640	Transcriptional regulator
B4918_RS11480	COG0667	Aldo Keto reductase
B4918_RS11485	COG2814	Major facilitator Superfamily
B4918_RS11515	COG0840	transmembrane signaling receptor activity
B4918_RS11535	COG3949	Membrane
B4918_RS11540	COG0783	Belongs to the Dps family
B4918_RS11555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B4918_RS11565	COG1231	oxidoreductase activity
B4918_RS11570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4918_RS11575	COG4989	oxidoreductase activity
B4918_RS11580	COG0523	cobalamin synthesis protein
B4918_RS11585	COG0456	acetyltransferase
B4918_RS11590	COG0803	Belongs to the bacterial solute-binding protein 9 family
B4918_RS11600	COG0702	epimerase
B4918_RS11610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B4918_RS11620	COG4166	transmembrane transport
B4918_RS11635	COG0406	alpha-ribazole phosphatase activity
B4918_RS11645	COG5337	Spore coat protein CotH
B4918_RS11650	COG1051	belongs to the nudix hydrolase family
B4918_RS11655	COG0586	Pfam SNARE associated Golgi protein
B4918_RS11660	COG2244	polysaccharide biosynthetic process
B4918_RS11670	COG0701	Predicted permease
B4918_RS11675	COG3689	TIGRFAM TIGR03943 family protein
B4918_RS11680	COG1607	acyl-coa hydrolase
B4918_RS11690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B4918_RS11705	COG0702	epimerase
B4918_RS11710	COG2839	Protein conserved in bacteria
B4918_RS11715	COG1253	flavin adenine dinucleotide binding
B4918_RS11740	COG1114	Component of the transport system for branched-chain amino acids
B4918_RS11745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B4918_RS11765	COG0860	N-Acetylmuramoyl-L-alanine amidase
B4918_RS11775	COG1876	peptidase activity
B4918_RS11790	COG2211	Major facilitator Superfamily
B4918_RS11805	COG0860	N-Acetylmuramoyl-L-alanine amidase
B4918_RS11815	COG0561	phosphatase activity
B4918_RS11820	COG1846	Transcriptional regulator
B4918_RS11825	COG2814	Major facilitator Superfamily
B4918_RS11835	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B4918_RS11855	COG1819	glycosyl
B4918_RS11860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4918_RS11865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4918_RS11895	COG0456	acetyltransferase
B4918_RS12000	COG3874	Sporulation protein YtfJ
B4918_RS12025	COG2226	methyltransferase
B4918_RS12045	COG1082	Xylose isomerase domain protein TIM barrel
B4918_RS12050	COG0346	lactoylglutathione lyase activity
B4918_RS12060	COG0604	alcohol dehydrogenase
B4918_RS12085	COG0426	domain, Protein
B4918_RS12085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B4918_RS12095	COG0386	Belongs to the glutathione peroxidase family
B4918_RS12100	COG1305	Transglutaminase-like
B4918_RS12105	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
B4918_RS12110	COG0714	Associated with various cellular activities
B4918_RS12115	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B4918_RS12120	COG1140	nitrate reductase beta subunit
B4918_RS12125	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B4918_RS12130	COG2181	nitrate reductase activity
B4918_RS12135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B4918_RS12140	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B4918_RS12145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B4918_RS12150	COG0303	'Molybdopterin
B4918_RS12155	COG0314	molybdopterin synthase activity
B4918_RS12165	COG2223	nitrite transmembrane transporter activity
B4918_RS12185	COG1648	precorrin-2 dehydrogenase activity
B4918_RS12190	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
B4918_RS12195	COG1587	Uroporphyrinogen-III synthase
B4918_RS12195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B4918_RS12200	COG2146	nitrite reductase [NAD(P)H] activity
B4918_RS12205	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B4918_RS12210	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
B4918_RS12245	COG2359	stage V sporulation protein S
B4918_RS12275	COG0457	Tetratricopeptide repeat
B4918_RS12290	COG1418	mRNA catabolic process
B4918_RS12295	COG0488	(ABC) transporter
B4918_RS12310	COG0629	single-stranded DNA binding
B4918_RS12320	COG1413	lyase activity
B4918_RS12335	COG2136	Putative SAM-dependent methyltransferase
B4918_RS12335	COG2521	methyltransferase
B4918_RS12340	COG0018	arginyl-trna synthetase
B4918_RS12385	COG0017	Asparaginyl-tRNA synthetase
B4918_RS12390	COG0733	neurotransmitter:sodium symporter activity
B4918_RS12415	COG2610	gluconate transmembrane transporter activity
B4918_RS12425	COG1794	racemase activity, acting on amino acids and derivatives
B4918_RS12435	COG0456	acetyltransferase
B4918_RS12450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B4918_RS12475	COG0546	phosphoglycolate phosphatase activity
B4918_RS12505	COG0768	penicillin binding
B4918_RS12515	COG0204	Acyl-transferase
B4918_RS12520	COG1272	protein, Hemolysin III
B4918_RS12530	COG0805	protein transport
B4918_RS12540	COG1307	EDD domain protein, DegV family
B4918_RS12550	COG1999	signal sequence binding
B4918_RS12555	COG0071	Belongs to the small heat shock protein (HSP20) family
B4918_RS12560	COG0367	asparagine synthase
B4918_RS12575	COG0860	N-Acetylmuramoyl-L-alanine amidase
B4918_RS12580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4918_RS12585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B4918_RS12605	COG1335	isochorismatase
B4918_RS12610	COG1051	belongs to the nudix hydrolase family
B4918_RS12615	COG0668	transmembrane transport
B4918_RS12620	COG2203	Gaf domain
B4918_RS12620	COG4585	Histidine kinase
B4918_RS12625	COG2197	response regulator
B4918_RS12630	COG1737	Transcriptional regulator
B4918_RS12635	COG0384	phenazine biosynthesis protein PhzF
B4918_RS12640	COG1064	alcohol dehydrogenase
B4918_RS12670	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B4918_RS12710	COG1174	glycine betaine transport
B4918_RS12745	COG1253	flavin adenine dinucleotide binding
B4918_RS12750	COG1012	belongs to the aldehyde dehydrogenase family
B4918_RS12755	COG5506	Protein of unknown function (DUF1694)
B4918_RS12775	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B4918_RS12780	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B4918_RS12785	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B4918_RS12790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B4918_RS12795	COG0456	acetyltransferase
B4918_RS12800	COG3829	transcription factor binding
B4918_RS12805	COG1509	lysine 2,3-aminomutase activity
B4918_RS12840	COG3064	Membrane
B4918_RS12840	COG4991	sh3 domain protein
B4918_RS12840	COG0515	serine threonine protein kinase
B4918_RS12850	COG0671	phosphoesterase, PA-phosphatase related
B4918_RS12855	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B4918_RS12860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4918_RS12940	COG0300	oxidoreductase activity
B4918_RS12960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B4918_RS12960	COG4499	WXG100 protein secretion system (Wss), protein YukC
B4918_RS12970	COG2814	Major facilitator Superfamily
B4918_RS12975	COG4841	protein insertion into membrane
B4918_RS12980	COG0372	Belongs to the citrate synthase family
B4918_RS12985	COG2079	MmgE PrpD family protein
B4918_RS12990	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B4918_RS12995	COG1960	acyl-CoA dehydrogenase activity
B4918_RS13000	COG2084	Dehydrogenase
B4918_RS13010	COG1280	lysine exporter protein (LysE YggA)
B4918_RS13015	COG1024	Enoyl-CoA hydratase
B4918_RS13030	COG0420	3'-5' exonuclease activity
B4918_RS13035	COG0419	ATPase involved in DNA repair
B4918_RS13060	COG2223	nitrite transmembrane transporter activity
B4918_RS13070	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS13075	COG1169	isochorismate synthase
B4918_RS13080	COG1021	2,3-dihydroxybenzoate-AMP ligase
B4918_RS13085	COG1535	isochorismatase
B4918_RS13085	COG3433	isochorismatase activity
B4918_RS13090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B4918_RS13095	COG3251	PFAM MbtH domain protein
B4918_RS13100	COG2814	Major facilitator Superfamily
B4918_RS13115	COG0776	regulation of translation
B4918_RS13125	COG2318	DinB family
B4918_RS13135	COG1115	amino acid carrier protein
B4918_RS13155	COG1187	pseudouridine synthase activity
B4918_RS13160	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B4918_RS13165	COG1136	(ABC) transporter
B4918_RS13210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B4918_RS13225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4918_RS13260	COG1247	-acetyltransferase
B4918_RS13295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4918_RS13325	COG0583	DNA-binding transcription factor activity
B4918_RS13330	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B4918_RS13340	COG0583	DNA-binding transcription factor activity
B4918_RS13345	COG2258	MOSC domain
B4918_RS13360	COG1132	(ABC) transporter
B4918_RS13365	COG1132	(ABC) transporter
B4918_RS13395	COG1396	sequence-specific DNA binding
B4918_RS13425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B4918_RS13430	COG1595	DNA-templated transcription, initiation
B4918_RS13455	COG1649	PFAM Uncharacterised BCR, COG1649
B4918_RS13480	COG2971	BadF BadG BcrA BcrD
B4918_RS13490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B4918_RS13500	COG1846	Transcriptional regulator
B4918_RS13515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4918_RS13530	COG3615	Tellurite resistance protein tehB
B4918_RS13530	COG0500	methyltransferase
B4918_RS13545	COG3961	Belongs to the TPP enzyme family
B4918_RS13590	COG2195	Cleaves the N-terminal amino acid of tripeptides
B4918_RS13615	COG2002	toxin-antitoxin pair type II binding
B4918_RS13625	COG0730	response to heat
B4918_RS13635	COG1686	Belongs to the peptidase S11 family
B4918_RS13650	COG2814	Major facilitator Superfamily
B4918_RS13680	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS13735	COG0741	lytic transglycosylase activity
B4918_RS13745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4918_RS13755	COG0456	acetyltransferase
B4918_RS13765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B4918_RS13770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B4918_RS13775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B4918_RS13790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B4918_RS13800	COG2234	aminopeptidase activity
B4918_RS13805	COG2814	Major facilitator Superfamily
B4918_RS13855	COG1396	sequence-specific DNA binding
B4918_RS13870	COG0726	polysaccharide deacetylase
B4918_RS13915	COG3547	Transposase (IS116 IS110 IS902 family)
B4918_RS13930	COG0768	penicillin binding
B4918_RS13935	COG1595	DNA-templated transcription, initiation
B4918_RS13960	COG1408	metallophosphoesterase
B4918_RS13970	COG1131	(ABC) transporter
B4918_RS13980	COG1309	transcriptional regulator
B4918_RS13995	COG1960	acyl-CoA dehydrogenase activity
B4918_RS14000	COG0439	Biotin carboxylase
B4918_RS14005	COG0511	ligase activity, forming carbon-carbon bonds
B4918_RS14010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B4918_RS14015	COG1024	Enoyl-CoA hydratase
B4918_RS14020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B4918_RS14025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B4918_RS14035	COG3547	Transposase (IS116 IS110 IS902 family)
B4918_RS14060	COG1686	Belongs to the peptidase S11 family
B4918_RS14090	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B4918_RS14105	COG3227	Zinc metalloprotease (Elastase)
B4918_RS14110	COG2207	Transcriptional regulator
B4918_RS14140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B4918_RS14150	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS14155	COG1733	regulation of RNA biosynthetic process
B4918_RS14200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4918_RS14225	COG2323	membrane
B4918_RS14235	COG0693	protein deglycase activity
B4918_RS14245	COG3386	PFAM SMP-30 Gluconolaconase
B4918_RS14255	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
B4918_RS14260	COG3773	Cell wall hydrolase
B4918_RS14270	COG0745	RESPONSE REGULATOR receiver
B4918_RS14275	COG2205	protein histidine kinase activity
B4918_RS14280	COG0583	DNA-binding transcription factor activity
B4918_RS14285	COG0667	Aldo Keto reductase
B4918_RS14305	COG1136	(ABC) transporter
B4918_RS14310	COG0577	efflux transmembrane transporter activity
B4918_RS14335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4918_RS14345	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B4918_RS14400	COG2124	cytochrome p450
B4918_RS14440	COG0561	phosphatase activity
B4918_RS14445	COG5002	protein histidine kinase activity
B4918_RS14460	COG1819	glycosyl
B4918_RS14465	COG1794	racemase activity, acting on amino acids and derivatives
B4918_RS14505	COG2076	Multidrug Resistance protein
B4918_RS14510	COG2076	Multidrug Resistance protein
B4918_RS14515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B4918_RS14515	COG0723	plastoquinol--plastocyanin reductase activity
B4918_RS14520	COG2814	Major facilitator Superfamily
B4918_RS14540	COG5002	protein histidine kinase activity
B4918_RS14560	COG0415	Belongs to the DNA photolyase family
B4918_RS14570	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B4918_RS14605	COG1522	sequence-specific DNA binding
B4918_RS14610	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B4918_RS14630	COG2155	Conserved Protein
B4918_RS14635	COG0697	spore germination
B4918_RS14690	COG1957	nucleoside hydrolase
B4918_RS14725	COG1113	amino acid transport
B4918_RS14730	COG1280	lysine exporter protein (LysE YggA)
B4918_RS14735	COG3403	YqcI/YcgG family
B4918_RS14745	COG5577	PFAM Coat F domain
B4918_RS14760	COG1533	DNA photolyase activity
B4918_RS14800	COG2205	protein histidine kinase activity
B4918_RS14865	COG2169	Transcriptional regulator
B4918_RS14895	COG0604	alcohol dehydrogenase
B4918_RS14900	COG0671	phosphoesterase, PA-phosphatase related
B4918_RS14995	COG0584	glycerophosphoryl diester phosphodiesterase
B4918_RS15015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4918_RS15020	COG0697	spore germination
B4918_RS15045	COG0494	nUDIX hydrolase
B4918_RS15080	COG0592	DNA-directed DNA polymerase activity
B4918_RS15085	COG1051	belongs to the nudix hydrolase family
B4918_RS15110	COG3878	Protein conserved in bacteria
B4918_RS15140	COG4667	esterase of the alpha-beta hydrolase superfamily
B4918_RS15180	COG0322	excinuclease ABC activity
B4918_RS15215	COG1819	glycosyl
B4918_RS15220	COG1819	glycosyl
B4918_RS15235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B4918_RS15265	COG0745	RESPONSE REGULATOR receiver
B4918_RS15270	COG5002	protein histidine kinase activity
B4918_RS15285	COG1136	(ABC) transporter
B4918_RS15290	COG0577	efflux transmembrane transporter activity
B4918_RS15295	COG1073	alpha beta
B4918_RS15305	COG0076	glutamate decarboxylase activity
B4918_RS15320	COG1523	belongs to the glycosyl hydrolase 13 family
B4918_RS15325	COG3227	Zinc metalloprotease (Elastase)
B4918_RS15330	COG0737	Belongs to the 5'-nucleotidase family
B4918_RS15350	COG0346	lactoylglutathione lyase activity
B4918_RS15355	COG0201	protein transport
B4918_RS15360	COG0697	spore germination
B4918_RS15365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4918_RS15400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4918_RS15415	COG2959	enzyme of heme biosynthesis
B4918_RS15420	COG3773	Cell wall hydrolase
B4918_RS15420	COG3409	Peptidoglycan-binding domain 1 protein
B4918_RS15455	COG1309	transcriptional regulator
B4918_RS15475	COG3284	Transcriptional regulator
B4918_RS15495	COG1349	DNA-binding transcription factor activity
B4918_RS15510	COG1959	2 iron, 2 sulfur cluster binding
B4918_RS15525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B4918_RS15530	COG0508	dehydrogenase complex catalyzes the overall conversion of
B4918_RS15535	COG0022	dehydrogenase e1 component
B4918_RS15540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B4918_RS15550	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS15580	COG4176	ABC-type proline glycine betaine transport system permease component
B4918_RS15585	COG0517	IMP dehydrogenase activity
B4918_RS15585	COG4175	Glycine betaine
B4918_RS15615	COG2153	protein acetylation
B4918_RS15635	COG3397	chitin binding
B4918_RS15640	COG1819	glycosyl
B4918_RS15650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B4918_RS15660	COG2205	protein histidine kinase activity
B4918_RS15665	COG2226	methyltransferase
B4918_RS15670	COG2315	Protein conserved in bacteria
B4918_RS15720	COG0456	acetyltransferase
B4918_RS15725	COG3973	AAA domain
B4918_RS15740	COG0514	ATP-dependent DNA helicase (RecQ)
B4918_RS15775	COG4637	Psort location Cytoplasmic, score
B4918_RS15795	COG3397	chitin binding
B4918_RS15810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B4918_RS15815	COG1115	amino acid carrier protein
B4918_RS15820	COG1012	belongs to the aldehyde dehydrogenase family
B4918_RS15825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B4918_RS15835	COG3938	Belongs to the proline racemase family
B4918_RS15840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B4918_RS15880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B4918_RS15885	COG1078	dGTPase activity
B4918_RS15890	COG0586	Pfam SNARE associated Golgi protein
B4918_RS15900	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
B4918_RS15905	COG4166	transmembrane transport
B4918_RS15915	COG4948	Mandelate Racemase Muconate Lactonizing
B4918_RS15930	COG0667	Aldo Keto reductase
B4918_RS15975	COG3850	Histidine kinase
B4918_RS15975	COG5002	protein histidine kinase activity
B4918_RS15980	COG0745	RESPONSE REGULATOR receiver
B4918_RS16005	COG1164	Oligoendopeptidase f
B4918_RS16010	COG1307	EDD domain protein, DegV family
B4918_RS16050	COG2814	Major facilitator Superfamily
B4918_RS16060	COG1664	Polymer-forming cytoskeletal
B4918_RS16065	COG0789	Transcriptional regulator
B4918_RS16070	COG4533	DNA binding
B4918_RS16125	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4918_RS16140	COG3547	Transposase (IS116 IS110 IS902 family)
B4918_RS16215	COG1802	Transcriptional regulator
B4918_RS16215	COG4626	Terminase
B4918_RS16300	COG1191	sigma factor activity
B4918_RS16325	COG3645	SOS response
B4918_RS16325	COG3646	Phage regulatory protein
B4918_RS16340	COG1396	sequence-specific DNA binding
B4918_RS16375	COG2261	transglycosylase associated protein
B4918_RS16390	COG2226	methyltransferase
B4918_RS16430	COG0436	Aminotransferase
B4918_RS16435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B4918_RS16445	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B4918_RS16460	COG1131	(ABC) transporter
B4918_RS16510	COG0628	permease
B4918_RS16530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B4918_RS16535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B4918_RS16565	COG2746	aminoglycoside 3-N-acetyltransferase activity
B4918_RS16575	COG0697	spore germination
B4918_RS16580	COG2318	DinB family
B4918_RS16600	COG4912	Dna alkylation repair
B4918_RS16605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B4918_RS16610	COG0346	lactoylglutathione lyase activity
B4918_RS16615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4918_RS16630	COG0726	polysaccharide deacetylase
B4918_RS16650	COG0861	Integral membrane protein TerC family
B4918_RS16655	COG1368	sulfuric ester hydrolase activity
B4918_RS16660	COG0488	(ABC) transporter
B4918_RS16665	COG1033	growth of symbiont in host cell
B4918_RS16665	COG2409	Drug exporters of the RND superfamily
B4918_RS16670	COG1309	transcriptional regulator
B4918_RS16685	COG0287	Prephenate dehydrogenase
B4918_RS16705	COG1605	Chorismate mutase
B4918_RS16705	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B4918_RS16740	COG3584	3D domain protein
B4918_RS16740	COG1388	LysM domain
B4918_RS16770	COG1879	ABC-type sugar transport system periplasmic component
B4918_RS16780	COG1172	Belongs to the binding-protein-dependent transport system permease family
B4918_RS16785	COG1129	ABC transporter
B4918_RS16790	COG2390	Transcriptional regulator
B4918_RS16795	COG1070	Carbohydrate kinase
B4918_RS16825	COG2329	Antibiotic biosynthesis monooxygenase
B4918_RS16840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B4918_RS16860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B4918_RS16865	COG4187	Peptidase family M20/M25/M40
B4918_RS16880	COG0833	amino acid
B4918_RS16890	COG1690	Belongs to the RtcB family
B4918_RS16895	COG3239	Fatty acid desaturase
B4918_RS16905	COG2720	vancomycin resistance protein
B4918_RS16910	COG1785	Belongs to the alkaline phosphatase family
B4918_RS16920	COG3655	Transcriptional regulator
B4918_RS16940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4918_RS16945	COG0346	lactoylglutathione lyase activity
B4918_RS16970	COG0714	Associated with various cellular activities
B4918_RS16995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B4918_RS17000	COG0753	catalase activity
B4918_RS17035	COG5444	nuclease activity
B4918_RS17065	COG0778	Nitroreductase
B4918_RS17070	COG1846	Transcriptional regulator
B4918_RS17095	COG3831	ATPase activity
B4918_RS17095	COG4884	unkown
B4918_RS17105	COG1136	(ABC) transporter
B4918_RS17125	COG2207	Transcriptional regulator
B4918_RS17130	COG0456	acetyltransferase
B4918_RS17140	COG2816	NAD+ diphosphatase activity
B4918_RS17145	COG0697	spore germination
B4918_RS17150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4918_RS17190	COG0730	response to heat
B4918_RS17200	COG0833	amino acid
B4918_RS17265	COG5002	protein histidine kinase activity
B4918_RS17325	COG1984	allophanate hydrolase subunit 2
B4918_RS17330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B4918_RS17335	COG1414	Transcriptional regulator
B4918_RS17350	COG0640	Transcriptional regulator
B4918_RS17360	COG1960	acyl-CoA dehydrogenase activity
B4918_RS17415	COG3848	Pyruvate phosphate dikinase
B4918_RS17415	COG0574	Belongs to the PEP-utilizing enzyme family
B4918_RS17425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4918_RS17445	COG1063	alcohol dehydrogenase
B4918_RS17455	COG1027	Aspartate ammonia-lyase
B4918_RS17460	COG0252	asparaginase activity
B4918_RS17465	COG1396	sequence-specific DNA binding
B4918_RS17495	COG5002	protein histidine kinase activity
B4918_RS17520	COG2207	Transcriptional regulator
B4918_RS17540	COG0322	excinuclease ABC activity
B4918_RS17545	COG0531	amino acid
B4918_RS17550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B4918_RS17560	COG0531	amino acid
B4918_RS17575	COG0784	Response regulator, receiver
B4918_RS17580	COG4191	Histidine kinase
B4918_RS17590	COG1115	amino acid carrier protein
B4918_RS17600	COG2124	cytochrome p450
B4918_RS17615	COG0737	Belongs to the 5'-nucleotidase family
B4918_RS17620	COG2267	carboxylic ester hydrolase activity
B4918_RS17625	COG1335	isochorismatase
B4918_RS17645	COG0583	DNA-binding transcription factor activity
B4918_RS17655	COG0598	Magnesium transport protein CorA
B4918_RS17680	COG1073	alpha beta
B4918_RS17700	COG0415	Belongs to the DNA photolyase family
B4918_RS17705	COG0288	reversible hydration of carbon dioxide
B4918_RS17715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B4918_RS17720	COG5609	conserved protein (DUF2294)
B4918_RS17735	COG0697	spore germination
B4918_RS17740	COG0726	polysaccharide deacetylase
B4918_RS17750	COG1575	Belongs to the MenA family. Type 1 subfamily
B4918_RS17755	COG0803	Belongs to the bacterial solute-binding protein 9 family
B4918_RS17760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B4918_RS17765	COG1121	(ABC) transporter
B4918_RS17785	COG0798	PFAM Bile acid sodium symporter
B4918_RS17790	COG0346	lactoylglutathione lyase activity
B4918_RS17795	COG0640	Transcriptional regulator
B4918_RS17810	COG0583	DNA-binding transcription factor activity
B4918_RS17840	COG3547	Transposase (IS116 IS110 IS902 family)
B4918_RS17860	COG1476	TRANSCRIPTIONal
B4918_RS17870	COG0825	malonyl-CoA metabolic process
B4918_RS17885	COG3320	Male sterility
B4918_RS17885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B4918_RS17895	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS17900	COG1522	sequence-specific DNA binding
B4918_RS17915	COG0346	lactoylglutathione lyase activity
B4918_RS17950	COG0745	RESPONSE REGULATOR receiver
B4918_RS17955	COG5002	protein histidine kinase activity
B4918_RS17955	COG3850	Histidine kinase
B4918_RS17995	COG0277	FAD linked oxidase domain protein
B4918_RS18010	COG1136	(ABC) transporter
B4918_RS18050	COG2814	Major facilitator Superfamily
B4918_RS18070	COG2515	1-aminocyclopropane-1-carboxylate deaminase
B4918_RS18090	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B4918_RS18110	COG0577	efflux transmembrane transporter activity
B4918_RS18120	COG5002	protein histidine kinase activity
B4918_RS18120	COG3850	Histidine kinase
B4918_RS18135	COG1846	Transcriptional regulator
B4918_RS18140	COG0456	acetyltransferase
B4918_RS18150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4918_RS18165	COG1619	proteins homologs of microcin C7 resistance protein MccF
B4918_RS18185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B4918_RS18205	COG0662	Cupin 2, conserved barrel domain protein
B4918_RS18215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4918_RS18215	COG2207	Transcriptional regulator
B4918_RS18240	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4918_RS18240	COG3409	Peptidoglycan-binding domain 1 protein
B4918_RS18255	COG2814	Major facilitator Superfamily
B4918_RS18450	COG1876	peptidase activity
B4918_RS18455	COG2843	Capsule synthesis protein
B4918_RS18465	COG0477	Major facilitator Superfamily
B4918_RS18480	COG1846	Transcriptional regulator
B4918_RS18485	COG2814	Major facilitator Superfamily
B4918_RS18500	COG2031	fatty acid transporter
B4918_RS18510	COG2249	NAD(P)H dehydrogenase (quinone) activity
B4918_RS18565	COG1288	antiporter activity
B4918_RS18570	COG2356	endonuclease I
B4918_RS18580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B4918_RS18585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B4918_RS18605	COG1733	regulation of RNA biosynthetic process
B4918_RS18610	COG0778	Nitroreductase
B4918_RS18645	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS18655	COG1131	(ABC) transporter
B4918_RS18680	COG1011	Hydrolase
B4918_RS18715	COG1051	belongs to the nudix hydrolase family
B4918_RS18725	COG0346	lactoylglutathione lyase activity
B4918_RS18730	COG1940	carbohydrate kinase activity
B4918_RS18735	COG0738	Major facilitator superfamily
B4918_RS18740	COG0110	maltose O-acetyltransferase activity
B4918_RS18745	COG0180	Tryptophanyl-tRNA synthetase
B4918_RS18755	COG0628	permease
B4918_RS18800	COG0477	Major facilitator Superfamily
B4918_RS18830	COG1253	flavin adenine dinucleotide binding
B4918_RS18835	COG0789	Transcriptional regulator
B4918_RS18840	COG0697	spore germination
B4918_RS18855	COG1357	PFAM Pentapeptide repeats (8 copies)
B4918_RS18860	COG3813	Protein conserved in bacteria
B4918_RS18865	COG2706	6-phosphogluconolactonase activity
B4918_RS18870	COG1070	Carbohydrate kinase
B4918_RS18875	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B4918_RS18880	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B4918_RS18885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B4918_RS18890	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B4918_RS18915	COG0814	amino acid
B4918_RS18940	COG1393	Belongs to the ArsC family
B4918_RS18945	COG1733	regulation of RNA biosynthetic process
B4918_RS18950	COG2188	Transcriptional regulator
B4918_RS18955	COG0673	inositol 2-dehydrogenase activity
B4918_RS18975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4918_RS19005	COG0318	PFAM AMP-dependent synthetase and ligase
B4918_RS19010	COG2249	NAD(P)H dehydrogenase (quinone) activity
B4918_RS19015	COG1733	regulation of RNA biosynthetic process
B4918_RS19020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B4918_RS19035	COG0726	polysaccharide deacetylase
B4918_RS19045	COG1191	sigma factor activity
B4918_RS19090	COG1151	hydroxylamine reductase activity
B4918_RS19155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4918_RS19160	COG0604	alcohol dehydrogenase
B4918_RS19165	COG1113	amino acid transport
B4918_RS19170	COG2814	Major facilitator Superfamily
B4918_RS19205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B4918_RS19210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B4918_RS19225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4918_RS19230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4918_RS19235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4918_RS19240	COG3739	integral membrane protein
B4918_RS19270	COG0583	DNA-binding transcription factor activity
B4918_RS19290	COG1193	negative regulation of DNA recombination
B4918_RS19305	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B4918_RS19310	COG1164	Oligoendopeptidase f
B4918_RS19315	COG2957	Belongs to the agmatine deiminase family
B4918_RS19345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B4918_RS19355	COG2271	Major facilitator Superfamily
B4918_RS19370	COG0584	glycerophosphoryl diester phosphodiesterase
B4918_RS19380	COG0640	Transcriptional regulator
B4918_RS19385	COG0604	alcohol dehydrogenase
B4918_RS19400	COG0457	Tetratricopeptide repeat
B4918_RS19410	COG0385	Bile acid
B4918_RS19415	COG0277	FAD linked oxidase domain protein
B4918_RS19435	COG1252	NADH dehydrogenase
B4918_RS19450	COG4641	Protein conserved in bacteria
B4918_RS19460	COG2089	acid synthase
B4918_RS19475	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B4918_RS19480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B4918_RS19485	COG1088	dTDP-glucose 4,6-dehydratase activity
B4918_RS19495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B4918_RS19500	COG0463	Glycosyl transferase, family 2
B4918_RS19505	COG0463	Glycosyl transferase, family 2
B4918_RS19515	COG0823	Involved in the tonB-independent uptake of proteins
B4918_RS19520	COG3397	chitin binding
B4918_RS19530	COG0697	spore germination
B4918_RS19550	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B4918_RS19570	COG0457	Tetratricopeptide repeat
B4918_RS19630	COG1309	transcriptional regulator
B4918_RS19645	COG1876	peptidase activity
B4918_RS19670	COG3852	Histidine kinase
B4918_RS19680	COG1285	pathogenesis
B4918_RS19690	COG2514	catechol 2,3-dioxygenase activity
B4918_RS19695	COG2720	vancomycin resistance protein
B4918_RS19725	COG1278	Cold shock
B4918_RS19735	COG0716	FMN binding
B4918_RS19745	COG0494	nUDIX hydrolase
B4918_RS19765	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS19775	COG0165	Argininosuccinate lyase
B4918_RS19790	COG4145	pantothenate transmembrane transporter activity
B4918_RS19800	COG1012	belongs to the aldehyde dehydrogenase family
B4918_RS19805	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS19815	COG1657	PFAM Prenyltransferase squalene oxidase
B4918_RS19820	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
B4918_RS19825	COG2962	Rard protein
B4918_RS19830	COG3326	Membrane
B4918_RS19845	COG0489	protein tyrosine kinase activity
B4918_RS19855	COG0314	molybdopterin synthase activity
B4918_RS19860	COG0303	'Molybdopterin
B4918_RS19865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B4918_RS19870	COG2116	formate transmembrane transporter activity
B4918_RS19885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B4918_RS19890	COG5609	conserved protein (DUF2294)
B4918_RS19895	COG2427	Protein of unknown function (DUF1641)
B4918_RS19900	COG3383	formate dehydrogenase (NAD+) activity
B4918_RS19910	COG0697	spore germination
B4918_RS19955	COG2226	methyltransferase
B4918_RS19960	COG4166	transmembrane transport
B4918_RS19975	COG4166	transmembrane transport
B4918_RS19980	COG1301	dicarboxylic acid transport
B4918_RS19985	COG1316	TRANSCRIPTIONal
B4918_RS19995	COG1595	DNA-templated transcription, initiation
B4918_RS20005	COG1131	(ABC) transporter
B4918_RS20025	COG0673	inositol 2-dehydrogenase activity
B4918_RS20030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B4918_RS20035	COG0187	DNA topoisomerase II activity
B4918_RS20045	COG1832	CoA-binding protein
B4918_RS20050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B4918_RS20055	COG0745	RESPONSE REGULATOR receiver
B4918_RS20075	COG4841	protein insertion into membrane
B4918_RS20080	COG0824	Thioesterase
B4918_RS20105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4918_RS20120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B4918_RS20130	COG0726	polysaccharide deacetylase
B4918_RS20150	COG2211	Major facilitator Superfamily
B4918_RS20160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B4918_RS20180	COG0318	PFAM AMP-dependent synthetase and ligase
B4918_RS20185	COG1268	BioY protein
B4918_RS20190	COG0318	PFAM AMP-dependent synthetase and ligase
B4918_RS20195	COG1396	sequence-specific DNA binding
B4918_RS20235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4918_RS20250	COG5002	protein histidine kinase activity
B4918_RS20255	COG0400	carboxylic ester hydrolase activity
B4918_RS20260	COG0346	lactoylglutathione lyase activity
B4918_RS20265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B4918_RS20275	COG0069	glutamate synthase activity
B4918_RS20280	COG1902	pentaerythritol trinitrate reductase activity
B4918_RS20285	COG1329	Transcriptional regulator
B4918_RS20290	COG0010	Belongs to the arginase family
B4918_RS20345	COG4846	Membrane protein involved in cytochrome C biogenesis
B4918_RS20350	COG0785	Cytochrome C biogenesis protein
B4918_RS20375	COG1131	(ABC) transporter
B4918_RS20395	COG0583	DNA-binding transcription factor activity
B4918_RS20420	COG0730	response to heat
B4918_RS20450	COG1132	(ABC) transporter
B4918_RS20455	COG1132	(ABC) transporter
B4918_RS20490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B4918_RS20495	COG0737	Belongs to the 5'-nucleotidase family
B4918_RS20505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B4918_RS20525	COG1695	Transcriptional regulator
B4918_RS20530	COG0174	glutamine synthetase
B4918_RS20535	COG0789	Transcriptional regulator
B4918_RS20540	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
B4918_RS20545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B4918_RS20550	COG2860	membrane
B4918_RS20555	COG0464	growth
B4918_RS20585	COG3584	3D domain protein
B4918_RS20585	COG1388	LysM domain
B4918_RS20595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B4918_RS20595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B4918_RS20595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B4918_RS20600	COG1105	Belongs to the carbohydrate kinase PfkB family
B4918_RS20605	COG1349	DNA-binding transcription factor activity
B4918_RS20610	COG1979	alcohol dehydrogenase
B4918_RS20615	COG2322	membrane
B4918_RS20630	COG1113	amino acid transport
B4918_RS20655	COG1408	metallophosphoesterase
B4918_RS20660	COG2116	formate transmembrane transporter activity
B4918_RS20675	COG2217	Heavy metal translocating P-type atpase
B4918_RS20680	COG2608	mercury ion transmembrane transporter activity
B4918_RS20685	COG1937	Protein conserved in bacteria
B4918_RS20705	COG2819	hydrolase of the alpha beta superfamily
B4918_RS20710	COG1120	ATPase activity
B4918_RS20715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4918_RS20720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4918_RS20725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4918_RS20735	COG0708	Exodeoxyribonuclease III
B4918_RS20740	COG2169	Transcriptional regulator
B4918_RS20745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B4918_RS20750	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B4918_RS20760	COG2364	Membrane
B4918_RS20775	COG2267	carboxylic ester hydrolase activity
B4918_RS20780	COG5001	Diguanylate cyclase
B4918_RS20780	COG3300	MHYT domain
B4918_RS20820	COG1346	cytolysis
B4918_RS20830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4918_RS20845	COG0840	transmembrane signaling receptor activity
B4918_RS20850	COG0823	Involved in the tonB-independent uptake of proteins
B4918_RS20855	COG1404	Belongs to the peptidase S8 family
B4918_RS20860	COG3773	Cell wall hydrolase
B4918_RS20875	COG1368	sulfuric ester hydrolase activity
B4918_RS20880	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B4918_RS20905	COG4550	Control of competence regulator ComK, YlbF/YmcA
B4918_RS20915	COG1013	pyruvate-flavodoxin oxidoreductase activity
B4918_RS20920	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B4918_RS20920	COG0674	pyruvate-flavodoxin oxidoreductase activity
B4918_RS20930	COG2359	stage V sporulation protein S
B4918_RS20935	COG1692	metallophosphoesterase
B4918_RS20960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B4918_RS20965	COG1426	Protein conserved in bacteria
B4918_RS20980	COG0300	oxidoreductase activity
B4918_RS20985	COG0612	Peptidase, M16
B4918_RS20990	COG0612	Peptidase, M16
B4918_RS21015	COG2188	Transcriptional regulator
B4918_RS21035	COG0740	serine-type endopeptidase activity
B4918_RS21040	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B4918_RS21050	COG0527	aspartate kinase activity
B4918_RS21055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B4918_RS21060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B4918_RS21065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B4918_RS21070	COG1873	PFAM PRC-barrel domain
B4918_RS21075	COG0612	Peptidase, M16
B4918_RS21080	COG0726	polysaccharide deacetylase
B4918_RS21095	COG0196	riboflavin kinase activity
B4918_RS21110	COG1550	Protein conserved in bacteria
B4918_RS21120	COG1358	cellular component organization or biogenesis
B4918_RS21125	COG2740	Nucleic-acid-binding protein implicated in transcription termination
B4918_RS21130	COG0195	Participates in both transcription termination and antitermination
B4918_RS21150	COG0750	zinc metalloprotease
B4918_RS21160	COG4589	Belongs to the CDS family
B4918_RS21205	COG4974	Belongs to the 'phage' integrase family
B4918_RS21215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B4918_RS21220	COG0758	DNA mediated transformation
B4918_RS21225	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B4918_RS21265	COG1837	Belongs to the UPF0109 family
B4918_RS21275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B4918_RS21285	COG0552	protein localization to endoplasmic reticulum
B4918_RS21290	COG1196	nuclear chromosome segregation
B4918_RS21305	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS21310	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B4918_RS21325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B4918_RS21330	COG1461	Dihydroxyacetone kinase
B4918_RS21335	COG1302	Protein conserved in bacteria
B4918_RS21350	COG1564	THIamine pyrophosphokinase
B4918_RS21355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B4918_RS21365	COG0515	serine threonine protein kinase
B4918_RS21365	COG2815	serine threonine protein kinase
B4918_RS21370	COG0631	protein serine/threonine phosphatase activity
B4918_RS21380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B4918_RS21380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B4918_RS21395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B4918_RS21400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B4918_RS21420	COG1561	YicC-like family, N-terminal region
B4918_RS21425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B4918_RS21460	COG3069	C4-dicarboxylate transmembrane transporter activity
B4918_RS21520	COG0564	pseudouridine synthase activity
B4918_RS21540	COG3599	regulation of cell shape
B4918_RS21545	COG2302	S4 RNA-binding domain
B4918_RS21550	COG0762	integral membrane protein
B4918_RS21560	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B4918_RS21570	COG1873	PFAM PRC-barrel domain
B4918_RS21575	COG1191	sigma factor activity
B4918_RS21580	COG1191	sigma factor activity
B4918_RS21590	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B4918_RS21595	COG0849	cell division
B4918_RS21610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B4918_RS21615	COG0772	Belongs to the SEDS family
B4918_RS21635	COG0768	penicillin binding
B4918_RS21660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B4918_RS21680	COG1399	metal-binding, possibly nucleic acid-binding protein
B4918_RS21690	COG3480	Lon protease (S16) C-terminal proteolytic domain
B4918_RS21695	COG1752	Esterase of the alpha-beta hydrolase superfamily
B4918_RS21700	COG3314	Sporulation integral membrane protein YlbJ
B4918_RS21710	COG0742	ribosomal rna small subunit methyltransferase
B4918_RS21725	COG3679	Belongs to the UPF0342 family
B4918_RS21730	COG0406	alpha-ribazole phosphatase activity
B4918_RS21745	COG2340	Cysteine-rich secretory protein family
B4918_RS21760	COG3336	cytochrome c oxidase
B4918_RS21795	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B4918_RS21805	COG0772	Belongs to the SEDS family
B4918_RS21815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B4918_RS21820	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B4918_RS21830	COG4896	Protein conserved in bacteria
B4918_RS21855	COG0483	inositol monophosphate 1-phosphatase activity
B4918_RS21875	COG1982	Orn Lys Arg decarboxylase major
B4918_RS21925	COG0022	dehydrogenase e1 component
B4918_RS21930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B4918_RS21945	COG0561	phosphatase activity
B4918_RS21960	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B4918_RS21965	COG0569	domain protein
B4918_RS21985	COG0583	DNA-binding transcription factor activity
B4918_RS21990	COG0517	IMP dehydrogenase activity
B4918_RS22000	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
B4918_RS22010	COG4703	Protein of unknown function (DUF1797)
B4918_RS22025	COG2200	EAL domain
B4918_RS22030	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS22035	COG1408	metallophosphoesterase
B4918_RS22080	COG2814	Major facilitator Superfamily
B4918_RS22100	COG3209	COG3209 Rhs family protein
B4918_RS22120	COG2205	protein histidine kinase activity
B4918_RS22130	COG0436	Aminotransferase
B4918_RS22135	COG1609	Transcriptional regulator
B4918_RS22140	COG3833	ABC-type maltose transport systems, permease component
B4918_RS22145	COG1175	transmembrane transport
B4918_RS22150	COG2182	Extracellular solute-binding protein
B4918_RS22160	COG0366	Alpha amylase catalytic
B4918_RS22165	COG3842	ATPase activity
B4918_RS22205	COG0183	Belongs to the thiolase family
B4918_RS22240	COG1695	Transcriptional regulator
B4918_RS22245	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS22265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B4918_RS22270	COG0436	Aminotransferase
B4918_RS22305	COG2084	Dehydrogenase
B4918_RS22315	COG2199	diguanylate cyclase activity
B4918_RS22315	COG2203	Gaf domain
B4918_RS22320	COG0778	Nitroreductase
B4918_RS22345	COG2190	(PTS) system
B4918_RS22345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B4918_RS22345	COG1263	PTS System
B4918_RS22350	COG3711	transcriptional antiterminator
B4918_RS22370	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B4918_RS22400	COG1547	Domain of unknown function (DUF309)
B4918_RS22405	COG0456	acetyltransferase
B4918_RS22410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B4918_RS22415	COG4086	secreted protein
B4918_RS22420	COG0561	phosphatase activity
B4918_RS22425	COG0697	spore germination
B4918_RS22440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B4918_RS22465	COG0733	neurotransmitter:sodium symporter activity
B4918_RS22485	COG1686	Belongs to the peptidase S11 family
B4918_RS22495	COG1725	Transcriptional regulator
B4918_RS22500	COG1131	(ABC) transporter
B4918_RS22520	COG1846	Transcriptional regulator
B4918_RS22535	COG0598	Magnesium transport protein CorA
B4918_RS22560	COG4974	Belongs to the 'phage' integrase family
B4918_RS22570	COG0735	belongs to the Fur family
B4918_RS22575	COG1300	Membrane
B4918_RS22595	COG0667	Aldo Keto reductase
B4918_RS22600	COG0656	L-ascorbic acid biosynthetic process
B4918_RS22605	COG0456	acetyltransferase
B4918_RS22605	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B4918_RS22615	COG0737	Belongs to the 5'-nucleotidase family
B4918_RS22615	COG1525	nuclease
B4918_RS22615	COG4085	toxin activity
B4918_RS22625	COG0596	Alpha beta hydrolase
B4918_RS22630	COG2056	Na+-H+ antiporter family
B4918_RS22635	COG1609	Transcriptional regulator
B4918_RS22640	COG0456	acetyltransferase
B4918_RS22645	COG1073	alpha beta
B4918_RS22660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B4918_RS22660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B4918_RS22665	COG0307	riboflavin synthase, alpha
B4918_RS22695	COG1073	alpha beta
B4918_RS22695	COG2226	methyltransferase
B4918_RS22710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B4918_RS22730	COG0737	Belongs to the 5'-nucleotidase family
B4918_RS22740	COG1522	sequence-specific DNA binding
B4918_RS22785	COG0300	oxidoreductase activity
B4918_RS22790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4918_RS22795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B4918_RS22800	COG1760	l-serine dehydratase
B4918_RS22805	COG1760	l-serine dehydratase
B4918_RS22835	COG1285	pathogenesis
B4918_RS22845	COG2195	Cleaves the N-terminal amino acid of tripeptides
B4918_RS22850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4918_RS22865	COG1376	ErfK ybiS ycfS ynhG family protein
B4918_RS22870	COG4129	membrane
B4918_RS22875	COG1126	abc transporter atp-binding protein
B4918_RS22880	COG0765	amino acid transport
B4918_RS22885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B4918_RS22905	COG2323	membrane
B4918_RS22910	COG0772	Belongs to the SEDS family
B4918_RS22920	COG0508	dehydrogenase complex catalyzes the overall conversion of
B4918_RS22925	COG0022	dehydrogenase e1 component
B4918_RS22930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B4918_RS22935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B4918_RS22945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B4918_RS22950	COG0280	phosphate acetyltransferase
B4918_RS22960	COG3290	protein histidine kinase activity
B4918_RS22960	COG3829	transcription factor binding
B4918_RS22970	COG0584	glycerophosphoryl diester phosphodiesterase
B4918_RS22975	COG3093	addiction module antidote protein HigA
B4918_RS22995	COG0750	zinc metalloprotease
B4918_RS23000	COG0497	DNA recombination
B4918_RS23010	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B4918_RS23020	COG0142	geranyltranstransferase activity
B4918_RS23045	COG1302	Protein conserved in bacteria
B4918_RS23050	COG0439	Biotin carboxylase
B4918_RS23055	COG0511	ligase activity, forming carbon-carbon bonds
B4918_RS23100	COG3854	ATPases associated with a variety of cellular activities
B4918_RS23125	COG0006	proline dipeptidase activity
B4918_RS23140	COG3872	metal-dependent enzyme
B4918_RS23150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B4918_RS23185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B4918_RS23195	COG1609	Transcriptional regulator
B4918_RS23205	COG2076	Multidrug Resistance protein
B4918_RS23210	COG2076	Multidrug Resistance protein
B4918_RS23260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B4918_RS23330	COG1459	type II secretion system
B4918_RS23335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B4918_RS23390	COG1410	methionine synthase
B4918_RS23390	COG0646	methionine synthase
B4918_RS23395	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B4918_RS23395	COG0646	methionine synthase
B4918_RS23400	COG0626	cystathionine gamma-synthase activity
B4918_RS23405	COG0626	cystathionine gamma-synthase activity
B4918_RS23425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4918_RS23435	COG1940	carbohydrate kinase activity
B4918_RS23440	COG4483	Protein conserved in bacteria
B4918_RS23445	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B4918_RS23455	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B4918_RS23460	COG0704	Plays a role in the regulation of phosphate uptake
B4918_RS23470	COG0573	inorganic phosphate transmembrane transporter activity
B4918_RS23475	COG0573	inorganic phosphate transmembrane transporter activity
B4918_RS23490	COG0477	Major facilitator Superfamily
B4918_RS23495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B4918_RS23505	COG5521	maltodextrose utilization protein MalA
B4918_RS23520	COG0735	belongs to the Fur family
B4918_RS23525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B4918_RS23530	COG1121	(ABC) transporter
B4918_RS23535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4918_RS23565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B4918_RS23570	COG2384	SAM-dependent methyltransferase
B4918_RS23580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B4918_RS23585	COG0358	DNA primase activity
B4918_RS23605	COG0517	IMP dehydrogenase activity
B4918_RS23620	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B4918_RS23625	COG0295	cytidine deaminase activity
B4918_RS23630	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B4918_RS23640	COG1480	7TM receptor with intracellular HD hydrolase
B4918_RS23645	COG1702	phosphate starvation-inducible protein PhoH
B4918_RS23665	COG1610	YqeY-like protein
B4918_RS23675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B4918_RS23680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B4918_RS23710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B4918_RS23715	COG1733	regulation of RNA biosynthetic process
B4918_RS23740	COG1466	dna polymerase III delta subunit
B4918_RS23750	COG2333	competence protein COMEC
B4918_RS23750	COG0658	competence protein
B4918_RS23755	COG2131	deaminase
B4918_RS23760	COG1555	photosystem II stabilization
B4918_RS23760	COG1596	polysaccharide export
B4918_RS23765	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B4918_RS23775	COG2226	methyltransferase
B4918_RS23780	COG0799	negative regulation of ribosome biogenesis
B4918_RS23785	COG1713	HD superfamily hydrolase involved in NAD metabolism
B4918_RS23795	COG1534	Rna-binding protein
B4918_RS23805	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B4918_RS23810	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
B4918_RS23825	COG1191	sigma factor activity
B4918_RS23835	COG1595	DNA-templated transcription, initiation
B4918_RS23845	COG0778	Nitroreductase
B4918_RS23850	COG2357	RelA SpoT domain protein
B4918_RS23860	COG1785	Belongs to the alkaline phosphatase family
B4918_RS23870	COG2267	carboxylic ester hydrolase activity
B4918_RS23905	COG1404	Belongs to the peptidase S8 family
B4918_RS23910	COG3186	Phenylalanine-4-hydroxylase
B4918_RS23920	COG2514	catechol 2,3-dioxygenase activity
B4918_RS23925	COG2259	Doxx family
B4918_RS23965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4918_RS23980	COG1454	alcohol dehydrogenase
B4918_RS23980	COG1012	belongs to the aldehyde dehydrogenase family
B4918_RS23985	COG0626	cystathionine gamma-synthase activity
B4918_RS23990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B4918_RS24015	COG0768	penicillin binding
B4918_RS24050	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B4918_RS24080	COG0628	permease
B4918_RS24100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B4918_RS24115	COG1104	cysteine desulfurase activity
B4918_RS24120	COG1959	2 iron, 2 sulfur cluster binding
B4918_RS24125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B4918_RS24140	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B4918_RS24175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B4918_RS24185	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B4918_RS24185	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B4918_RS24190	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B4918_RS24195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B4918_RS24195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B4918_RS24205	COG2244	polysaccharide biosynthetic process
B4918_RS24210	COG2323	membrane
B4918_RS24220	COG1862	Preprotein translocase
B4918_RS24250	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B4918_RS24280	COG0157	Belongs to the NadC ModD family
B4918_RS24285	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B4918_RS24290	COG1104	cysteine desulfurase activity
B4918_RS24295	COG1827	regulation of RNA biosynthetic process
B4918_RS24300	COG2258	MOSC domain
B4918_RS24310	COG0077	Prephenate dehydratase
B4918_RS24315	COG0577	efflux transmembrane transporter activity
B4918_RS24320	COG0577	efflux transmembrane transporter activity
B4918_RS24325	COG1136	(ABC) transporter
B4918_RS24330	COG5002	protein histidine kinase activity
B4918_RS24335	COG0745	RESPONSE REGULATOR receiver
B4918_RS24345	COG3290	protein histidine kinase activity
B4918_RS24355	COG2868	ribosomal protein
B4918_RS24365	COG1530	ribonuclease E activity
B4918_RS24370	COG1994	Peptidase M50
B4918_RS24375	COG0739	heme binding
B4918_RS24380	COG2894	cell division
B4918_RS24395	COG1792	Involved in formation and maintenance of cell shape
B4918_RS24400	COG1077	Cell shape determining protein MreB Mrl
B4918_RS24430	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4918_RS24650	COG0285	dihydrofolate synthase activity
B4918_RS24665	COG1388	LysM domain
B4918_RS24675	COG0113	porphobilinogen synthase activity
B4918_RS24680	COG1587	Uroporphyrinogen-III synthase
B4918_RS24690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B4918_RS24700	COG1846	Transcriptional regulator
B4918_RS24705	COG1764	response to oxidative stress
B4918_RS24720	COG1067	ATP-dependent peptidase activity
B4918_RS24720	COG0470	DNA polymerase III
B4918_RS24805	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B4918_RS24825	COG0622	Phosphoesterase
B4918_RS24840	COG5401	PFAM Sporulation and spore germination
B4918_RS24860	COG1309	transcriptional regulator
B4918_RS24870	COG2197	response regulator
B4918_RS24875	COG2233	PERMEase
B4918_RS24880	COG0402	S-adenosylhomocysteine deaminase activity
B4918_RS24885	COG1983	PspC domain protein
B4918_RS24890	COG1396	sequence-specific DNA binding
B4918_RS24895	COG0697	spore germination
B4918_RS24915	COG1959	2 iron, 2 sulfur cluster binding
B4918_RS24920	COG1668	transmembrane transport
B4918_RS24925	COG4152	abc transporter atp-binding protein
B4918_RS24930	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
B4918_RS24935	COG1360	Flagellar Motor Protein
B4918_RS24940	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B4918_RS24945	COG1876	peptidase activity
B4918_RS24950	COG0824	Thioesterase
B4918_RS24955	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B4918_RS24960	COG1053	succinate dehydrogenase
B4918_RS24965	COG2009	succinate dehydrogenase
B4918_RS24970	COG1719	4-vinyl reductase, 4VR
B4918_RS24980	COG3118	belongs to the thioredoxin family
B4918_RS24985	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B4918_RS24990	COG2086	electron transfer activity
B4918_RS24995	COG1024	Enoyl-CoA hydratase
B4918_RS25000	COG1309	transcriptional regulator
B4918_RS25005	COG0318	PFAM AMP-dependent synthetase and ligase
B4918_RS25030	COG2318	DinB family
B4918_RS25050	COG1131	(ABC) transporter
B4918_RS25055	COG2205	protein histidine kinase activity
B4918_RS25060	COG0745	RESPONSE REGULATOR receiver
B4918_RS25070	COG4895	conserved protein (DUF2196)
B4918_RS25075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B4918_RS25085	COG4509	Sortase family
B4918_RS25090	COG1120	ATPase activity
B4918_RS25105	COG5386	Cell surface protein
B4918_RS25115	COG5386	Cell surface protein
B4918_RS25120	COG1114	Component of the transport system for branched-chain amino acids
B4918_RS25125	COG1187	pseudouridine synthase activity
B4918_RS25140	COG1796	DNA polymerase
B4918_RS25140	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B4918_RS25145	COG1286	toxin biosynthetic process
B4918_RS25170	COG0017	Asparaginyl-tRNA synthetase
B4918_RS25185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B4918_RS25195	COG1418	mRNA catabolic process
B4918_RS25210	COG2814	Major facilitator Superfamily
B4918_RS25215	COG1566	PFAM secretion protein HlyD family protein
B4918_RS25220	COG1309	transcriptional regulator
B4918_RS25225	COG1363	Peptidase, m42
B4918_RS25250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B4918_RS25265	COG1484	DNA-dependent DNA replication
B4918_RS25270	COG3611	Membrane attachment protein
B4918_RS25280	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B4918_RS25290	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B4918_RS25295	COG0237	dephospho-CoA kinase activity
B4918_RS25300	COG1971	Probably functions as a manganese efflux pump
B4918_RS25310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B4918_RS25310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B4918_RS25315	COG5002	protein histidine kinase activity
B4918_RS25320	COG0745	RESPONSE REGULATOR receiver
B4918_RS25350	COG0538	isocitrate dehydrogenase activity
B4918_RS25355	COG0372	Belongs to the citrate synthase family
B4918_RS25370	COG0628	permease
B4918_RS25375	COG3030	protein affecting phage T7 exclusion by the F plasmid
B4918_RS25400	COG1725	Transcriptional regulator
B4918_RS25405	COG0281	malic enzyme
B4918_RS25410	COG0587	DNA-directed DNA polymerase activity
B4918_RS25425	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B4918_RS25440	COG4109	DRTGG domain
B4918_RS25455	COG0006	proline dipeptidase activity
B4918_RS25485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4918_RS25490	COG0662	Cupin 2, conserved barrel domain protein
B4918_RS25505	COG1028	Short-chain dehydrogenase reductase Sdr
B4918_RS25510	COG0589	response to stress
B4918_RS25565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4918_RS25590	COG0827	DNA restriction-modification system
B4918_RS25595	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B4918_RS25600	COG3874	Sporulation protein YtfJ
B4918_RS25615	COG1574	metal-dependent hydrolase with the TIM-barrel fold
B4918_RS25625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B4918_RS25640	COG1104	cysteine desulfurase activity
B4918_RS25650	COG0583	DNA-binding transcription factor activity
B4918_RS25655	COG0697	spore germination
B4918_RS25660	COG1309	transcriptional regulator
B4918_RS25665	COG1956	GAF domain-containing protein
B4918_RS25670	COG0626	cystathionine gamma-synthase activity
B4918_RS25790	COG0110	maltose O-acetyltransferase activity
B4918_RS25795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B4918_RS25800	COG0454	-acetyltransferase
B4918_RS25805	COG0517	IMP dehydrogenase activity
B4918_RS25810	COG0123	including yeast histone deacetylase and acetoin utilization protein
B4918_RS25825	COG0745	RESPONSE REGULATOR receiver
B4918_RS25830	COG5002	protein histidine kinase activity
B4918_RS25835	COG0666	response to abiotic stimulus
B4918_RS25870	COG1609	Transcriptional regulator
B4918_RS25890	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B4918_RS25890	COG1605	Chorismate mutase
B4918_RS25895	COG4851	CamS sex pheromone cAM373 precursor
B4918_RS25900	COG3118	belongs to the thioredoxin family
B4918_RS25910	COG2309	aminopeptidase activity
B4918_RS25925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4918_RS25930	COG0697	spore germination
B4918_RS25935	COG0789	Transcriptional regulator
B4918_RS25950	COG1674	ftsk spoiiie
B4918_RS25965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B4918_RS25975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4918_RS25980	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
B4918_RS25985	COG1363	Peptidase, m42
B4918_RS25995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4918_RS26010	COG0510	thiamine kinase activity
B4918_RS26015	COG1523	belongs to the glycosyl hydrolase 13 family
B4918_RS26030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B4918_RS26035	COG1349	DNA-binding transcription factor activity
B4918_RS26040	COG1187	pseudouridine synthase activity
B4918_RS26045	COG2244	polysaccharide biosynthetic process
B4918_RS26050	COG2081	HI0933 family
B4918_RS26060	COG2814	Major facilitator Superfamily
B4918_RS26070	COG3832	glyoxalase III activity
B4918_RS26095	COG1329	Transcriptional regulator
B4918_RS26120	COG0314	molybdopterin synthase activity
B4918_RS26125	COG1763	Mo-molybdopterin cofactor biosynthetic process
B4918_RS26130	COG0303	'Molybdopterin
B4918_RS26140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B4918_RS26145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B4918_RS26170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B4918_RS26180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B4918_RS26220	COG2814	Major facilitator Superfamily
B4918_RS26225	COG0475	glutathione-regulated potassium exporter activity
B4918_RS26230	COG0490	domain, Protein
B4918_RS26235	COG0582	viral genome integration into host DNA
B4918_RS26245	COG1136	(ABC) transporter
B4918_RS26265	COG1242	4 iron, 4 sulfur cluster binding
B4918_RS26270	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B4918_RS26275	COG1794	racemase activity, acting on amino acids and derivatives
B4918_RS26295	COG2267	carboxylic ester hydrolase activity
B4918_RS26300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B4918_RS26305	COG0671	phosphoesterase, PA-phosphatase related
B4918_RS26310	COG0438	transferase activity, transferring glycosyl groups
B4918_RS26410	COG5002	protein histidine kinase activity
B4918_RS26415	COG3852	Histidine kinase
B4918_RS26425	COG2267	carboxylic ester hydrolase activity
B4918_RS26430	COG1368	sulfuric ester hydrolase activity
B4918_RS26455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B4918_RS26460	COG1116	anion transmembrane transporter activity
B4918_RS26465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B4918_RS26490	COG0494	nUDIX hydrolase
B4918_RS26525	COG2076	Multidrug Resistance protein
B4918_RS26530	COG2076	Multidrug Resistance protein
B4918_RS26535	COG0789	Transcriptional regulator
B4918_RS26550	COG0288	reversible hydration of carbon dioxide
B4918_RS26555	COG1271	oxidase subunit
B4918_RS26560	COG1294	oxidase, subunit
B4918_RS26580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4918_RS26605	COG1842	Phage shock protein A
B4918_RS26630	COG3859	Proton-coupled thiamine transporter YuaJ
B4918_RS26635	COG5002	protein histidine kinase activity
B4918_RS26640	COG0745	RESPONSE REGULATOR receiver
B4918_RS26670	COG1597	lipid kinase activity
B4918_RS26715	COG0586	Pfam SNARE associated Golgi protein
B4918_RS26725	COG0577	efflux transmembrane transporter activity
B4918_RS26730	COG1136	(ABC) transporter
B4918_RS26745	COG1131	(ABC) transporter
B4918_RS26750	COG5658	integral membrane protein
B4918_RS26755	COG0640	Transcriptional regulator
B4918_RS26765	COG0745	RESPONSE REGULATOR receiver
B4918_RS26770	COG2205	protein histidine kinase activity
B4918_RS26775	COG0577	efflux transmembrane transporter activity
B4918_RS26780	COG0577	efflux transmembrane transporter activity
B4918_RS26785	COG1136	(ABC) transporter
B4918_RS26790	COG0577	efflux transmembrane transporter activity
B4918_RS26825	COG3964	amidohydrolase
B4918_RS26850	COG4948	Mandelate Racemase Muconate Lactonizing
B4918_RS26860	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B4918_RS26865	COG0596	Alpha beta hydrolase
B4918_RS26875	COG1169	isochorismate synthase
B4918_RS26880	COG1575	Belongs to the MenA family. Type 1 subfamily
B4918_RS26885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B4918_RS26890	COG1278	Cold shock
B4918_RS26920	COG0058	SHG alpha-glucan phosphorylase activity
B4918_RS26930	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B4918_RS26960	COG0039	L-malate dehydrogenase activity
B4918_RS26965	COG1309	transcriptional regulator
B4918_RS27105	COG1285	pathogenesis
B4918_RS27110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B4918_RS27130	COG2155	Conserved Protein
B4918_RS27135	COG1098	S1 RNA binding domain
B4918_RS27140	COG0436	Aminotransferase
B4918_RS27145	COG1522	sequence-specific DNA binding
B4918_RS27150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B4918_RS27155	COG2267	carboxylic ester hydrolase activity
B4918_RS27165	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B4918_RS27185	COG5018	Exonuclease
B4918_RS27190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B4918_RS27210	COG0423	glycine-tRNA ligase activity
B4918_RS27215	COG2050	protein possibly involved in aromatic compounds catabolism
B4918_RS27225	COG1268	BioY protein
B4918_RS27230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B4918_RS27235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B4918_RS27250	COG3584	3D domain protein
B4918_RS27265	COG1252	NADH dehydrogenase
B4918_RS27275	COG3708	Transcriptional regulator
B4918_RS27290	COG1683	Conserved Protein
B4918_RS27315	COG0316	Belongs to the HesB IscA family
B4918_RS27330	COG1252	NADH dehydrogenase
B4918_RS27340	COG2274	protein secretion by the type I secretion system
B4918_RS27345	COG0390	transport system, permease component
B4918_RS27350	COG2824	Alkylphosphonate utilization operon protein PhnA
B4918_RS27400	COG4837	Protein of unknown function (DUF1462)
B4918_RS27405	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B4918_RS27415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B4918_RS27420	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B4918_RS27440	COG1358	cellular component organization or biogenesis
B4918_RS27450	COG2249	NAD(P)H dehydrogenase (quinone) activity
B4918_RS27455	COG0647	UMP catabolic process
B4918_RS27465	COG2445	Protein of unknown function DUF86
B4918_RS27470	COG1494	fructose-1,6-bisphosphatase
B4918_RS27490	COG4470	Protein conserved in bacteria
B4918_RS27500	COG0789	Transcriptional regulator
B4918_RS27505	COG4377	Putative membrane peptidase family (DUF2324)
B4918_RS27530	COG0739	heme binding
B4918_RS27540	COG3377	Domain of unknown function (DUF1805)
B4918_RS27545	COG0737	Belongs to the 5'-nucleotidase family
B4918_RS27575	COG0457	Tetratricopeptide repeat
B4918_RS27580	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4918_RS27580	COG3409	Peptidoglycan-binding domain 1 protein
B4918_RS27580	COG1388	LysM domain
B4918_RS27585	COG4824	toxin secretion phage lysis holin
B4918_RS27725	COG3331	DNA recombination
B4918_RS27805	COG3646	Phage regulatory protein
B4918_RS27820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B4918_RS27825	COG0582	viral genome integration into host DNA
B4918_RS27830	COG0719	Fe-S assembly protein
B4918_RS27835	COG0822	iron-sulfur transferase activity
B4918_RS27840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B4918_RS27845	COG0719	Fe-S assembly protein
B4918_RS27850	COG0396	ATPase activity
B4918_RS27855	COG1464	Belongs to the NlpA lipoprotein family
B4918_RS27860	COG1464	Belongs to the NlpA lipoprotein family
B4918_RS27865	COG2011	ABC-type metal ion transport system permease component
B4918_RS27880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B4918_RS27885	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B4918_RS27895	COG1393	Belongs to the ArsC family
B4918_RS27915	COG0039	L-malate dehydrogenase activity
B4918_RS27935	COG1309	transcriptional regulator
B4918_RS27940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B4918_RS27945	COG1960	acyl-CoA dehydrogenase activity
B4918_RS27950	COG0183	Belongs to the thiolase family
B4918_RS27955	COG1024	Enoyl-CoA hydratase
B4918_RS27955	COG1250	3-hydroxyacyl-CoA dehydrogenase
B4918_RS27965	COG1686	Belongs to the peptidase S11 family
B4918_RS27980	COG0011	TIGRFAM Protein of
B4918_RS27985	COG0840	transmembrane signaling receptor activity
B4918_RS28000	COG2814	Major facilitator Superfamily
B4918_RS28005	COG0531	amino acid
B4918_RS28030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B4918_RS28070	COG0586	Pfam SNARE associated Golgi protein
B4918_RS28080	COG1376	ErfK ybiS ycfS ynhG family protein
B4918_RS28085	COG0745	RESPONSE REGULATOR receiver
B4918_RS28120	COG0840	transmembrane signaling receptor activity
B4918_RS28125	COG2151	metal-sulfur cluster biosynthetic enzyme
B4918_RS28130	COG3227	Zinc metalloprotease (Elastase)
B4918_RS28150	COG0586	Pfam SNARE associated Golgi protein
B4918_RS28155	COG0475	glutathione-regulated potassium exporter activity
B4918_RS28160	COG0490	domain, Protein
B4918_RS28170	COG1115	amino acid carrier protein
B4918_RS28175	COG0783	Belongs to the Dps family
B4918_RS28195	COG1611	Belongs to the LOG family
B4918_RS28205	COG1528	Iron-storage protein
B4918_RS28215	COG2311	Membrane
B4918_RS28220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B4918_RS28225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B4918_RS28230	COG1115	amino acid carrier protein
B4918_RS28235	COG1115	amino acid carrier protein
B4918_RS28240	COG2910	NAD(P)H-binding
B4918_RS28260	COG0656	L-ascorbic acid biosynthetic process
B4918_RS28265	COG2814	Major facilitator Superfamily
B4918_RS28270	COG1733	regulation of RNA biosynthetic process
B4918_RS28280	COG1252	NADH dehydrogenase
B4918_RS28305	COG0840	transmembrane signaling receptor activity
B4918_RS28305	COG3290	protein histidine kinase activity
B4918_RS28340	COG0488	(ABC) transporter
B4918_RS28345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B4918_RS28350	COG3223	Belongs to the PsiE family
B4918_RS28360	COG1335	isochorismatase
B4918_RS28365	COG1522	sequence-specific DNA binding
B4918_RS28375	COG1522	sequence-specific DNA binding
B4918_RS28380	COG0288	reversible hydration of carbon dioxide
B4918_RS28385	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
B4918_RS28390	COG2233	PERMEase
B4918_RS28505	COG3104	oligopeptide transport
B4918_RS28545	COG0557	exoribonuclease II activity
B4918_RS28550	COG1647	Serine aminopeptidase, S33
B4918_RS28555	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B4918_RS28560	COG1346	cytolysis
B4918_RS28595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B4918_RS28610	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B4918_RS28620	COG3611	Membrane attachment protein
B4918_RS28630	COG1388	LysM domain
B4918_RS28630	COG3409	Peptidoglycan-binding domain 1 protein
B4918_RS28630	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4918_RS28635	COG4824	toxin secretion phage lysis holin
B4918_RS28775	COG3331	DNA recombination
B4918_RS28850	COG3646	Phage regulatory protein
B4918_RS28875	COG0582	viral genome integration into host DNA
B4918_RS28900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B4918_RS28915	COG2323	membrane
B4918_RS28930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B4918_RS28940	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B4918_RS28950	COG1051	belongs to the nudix hydrolase family
B4918_RS28960	COG0492	ferredoxin-NADP+ reductase activity
B4918_RS28965	COG0457	Tetratricopeptide repeat
B4918_RS28970	COG0110	maltose O-acetyltransferase activity
B4918_RS28990	COG1950	PFAM Membrane protein of
B4918_RS29000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B4918_RS29020	COG0789	Transcriptional regulator
B4918_RS29040	COG0583	DNA-binding transcription factor activity
B4918_RS29050	COG0655	NAD(P)H dehydrogenase (quinone) activity
B4918_RS29055	COG0488	(ABC) transporter
B4918_RS29065	COG1132	(ABC) transporter
B4918_RS29070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B4918_RS29075	COG3409	Peptidoglycan-binding domain 1 protein
B4918_RS29075	COG0793	Belongs to the peptidase S41A family
B4918_RS29080	COG2177	Part of the ABC transporter FtsEX involved in
B4918_RS29085	COG2884	Cell division ATP-binding protein ftsE
B4918_RS29115	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B4918_RS29120	COG1278	Cold shock
B4918_RS29125	COG1040	competence protein
B4918_RS29130	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B4918_RS29135	COG0791	NLP P60 protein
B4918_RS29135	COG1388	LysM domain
B4918_RS29140	COG1733	regulation of RNA biosynthetic process
B4918_RS29150	COG1307	EDD domain protein, DegV family
B4918_RS29155	COG1739	Uncharacterized protein family UPF0029
B4918_RS29160	COG1316	TRANSCRIPTIONal
B4918_RS29165	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B4918_RS29170	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B4918_RS29175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B4918_RS29185	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B4918_RS29185	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B4918_RS29210	COG1486	melibiose metabolic process
B4918_RS29215	COG1447	Phosphotransferase system cellobiose-specific component IIA
B4918_RS29220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B4918_RS29230	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B4918_RS29240	COG1447	Phosphotransferase system cellobiose-specific component IIA
B4918_RS29255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B4918_RS29260	COG1301	dicarboxylic acid transport
B4918_RS29280	COG1511	domain protein
B4918_RS29285	COG0583	DNA-binding transcription factor activity
B4918_RS29300	COG1271	oxidase subunit
B4918_RS29305	COG1294	oxidase, subunit
B4918_RS29310	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B4918_RS29320	COG1620	l-lactate permease
B4918_RS29330	COG2389	metal-binding protein
B4918_RS29345	COG1368	sulfuric ester hydrolase activity
B4918_RS29365	COG0791	NLP P60 protein
B4918_RS29365	COG1388	LysM domain
B4918_RS29370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B4918_RS29380	COG1215	transferase activity, transferring glycosyl groups
B4918_RS29390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B4918_RS29400	COG1388	LysM domain
B4918_RS29400	COG3584	3D domain protein
B4918_RS29425	COG4715	Zinc finger, swim domain protein
B4918_RS29430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B4918_RS29440	COG3547	Transposase (IS116 IS110 IS902 family)
B4918_RS29470	COG1191	sigma factor activity
B4918_RS29480	COG0577	efflux transmembrane transporter activity
B4918_RS29485	COG1136	(ABC) transporter
B4918_RS29510	COG5002	protein histidine kinase activity
B4918_RS29515	COG0745	RESPONSE REGULATOR receiver
B4918_RS29520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B4918_RS29525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B4918_RS29545	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B4918_RS29560	COG0438	transferase activity, transferring glycosyl groups
B4918_RS29565	COG1215	transferase activity, transferring glycosyl groups
B4918_RS29570	COG0438	transferase activity, transferring glycosyl groups
B4918_RS29585	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B4918_RS29590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B4918_RS29595	COG1086	Polysaccharide biosynthesis protein
B4918_RS29600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B4918_RS29605	COG4464	protein tyrosine phosphatase activity
B4918_RS29610	COG0489	protein tyrosine kinase activity
B4918_RS29615	COG3944	biosynthesis protein
B4918_RS29620	COG0489	protein tyrosine kinase activity
B4918_RS29635	COG1609	Transcriptional regulator
B4918_RS29645	COG0739	heme binding
B4918_RS29660	COG3279	Response regulator of the LytR AlgR family
B4918_RS29665	COG2385	sporulation resulting in formation of a cellular spore
B4918_RS29670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B4918_RS29680	COG4836	Membrane
B4918_RS29685	COG1007	ATP synthesis coupled electron transport
B4918_RS29690	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B4918_RS29695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B4918_RS29705	COG0839	Belongs to the complex I subunit 6 family
B4918_RS29725	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B4918_RS29740	COG3300	MHYT domain
B4918_RS29740	COG5001	Diguanylate cyclase
B4918_RS29795	COG0356	it plays a direct role in the translocation of protons across the membrane
B4918_RS29830	COG0698	ribose 5-phosphate isomerase
B4918_RS29845	COG2190	(PTS) system
B4918_RS29850	COG2259	Doxx family
B4918_RS29855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B4918_RS29875	COG0009	L-threonylcarbamoyladenylate synthase
B4918_RS29895	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B4918_RS29915	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B4918_RS29920	COG1494	fructose-1,6-bisphosphatase
B4918_RS29950	COG4821	SIS domain
B4918_RS29970	COG1960	acyl-CoA dehydrogenase activity
B4918_RS29975	COG1960	acyl-CoA dehydrogenase activity
B4918_RS29980	COG1250	3-hydroxyacyl-CoA dehydrogenase
B4918_RS29985	COG0183	Belongs to the thiolase family
B4918_RS29990	COG0247	lactate metabolic process
B4918_RS29990	COG2181	nitrate reductase activity
B4918_RS29995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B4918_RS30005	COG5001	Diguanylate cyclase
B4918_RS30005	COG3300	MHYT domain
B4918_RS30025	COG2197	response regulator
B4918_RS30030	COG4585	Histidine kinase
B4918_RS30035	COG0842	Transport permease protein
B4918_RS30040	COG1131	(ABC) transporter
B4918_RS30045	COG0024	Methionine aminopeptidase
B4918_RS30055	COG2234	aminopeptidase activity
B4918_RS30080	COG4506	Protein conserved in bacteria
B4918_RS30085	COG1619	proteins homologs of microcin C7 resistance protein MccF
B4918_RS30110	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B4918_RS30115	COG2814	Major facilitator Superfamily
B4918_RS30120	COG0789	Transcriptional regulator
B4918_RS30125	COG0584	glycerophosphoryl diester phosphodiesterase
B4918_RS30130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B4918_RS30140	COG1994	Peptidase M50
B4918_RS30150	COG1078	dGTPase activity
B4918_RS30155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4918_RS30160	COG1120	ATPase activity
B4918_RS30165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4918_RS30170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B4918_RS30190	COG0280	phosphate acetyltransferase
B4918_RS30205	COG3773	Cell wall hydrolase
B4918_RS30215	COG2363	Small membrane protein
B4918_RS30225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B4918_RS30230	COG2233	PERMEase
B4918_RS30235	COG0561	phosphatase activity
B4918_RS30240	COG2814	Major facilitator Superfamily
B4918_RS30250	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B4918_RS30255	COG1131	(ABC) transporter
B4918_RS30260	COG2755	lipolytic protein G-D-S-L family
B4918_RS30265	COG1609	Transcriptional regulator
B4918_RS30275	COG0460	homoserine dehydrogenase
B4918_RS30290	COG1011	Hydrolase
B4918_RS30295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B4918_RS30305	COG2197	response regulator
B4918_RS30310	COG2203	Gaf domain
B4918_RS30310	COG4585	Histidine kinase
B4918_RS30315	COG0351	phosphomethylpyrimidine kinase
B4918_RS30320	COG3706	GGDEF domain
B4918_RS30325	COG2879	small protein
B4918_RS30330	COG1966	Carbon starvation protein
B4918_RS30335	COG3279	Response regulator of the LytR AlgR family
B4918_RS30340	COG0477	Major facilitator Superfamily
B4918_RS30355	COG0438	transferase activity, transferring glycosyl groups
B4918_RS30370	COG0840	transmembrane signaling receptor activity
B4918_RS30380	COG1607	acyl-coa hydrolase
B4918_RS30385	COG1216	Glycosyl transferase, family 2
B4918_RS30400	COG1216	Glycosyl transferase, family 2
B4918_RS30410	COG4485	Bacterial membrane protein, YfhO
B4918_RS30415	COG0463	Glycosyl transferase, family 2
B4918_RS30425	COG1309	transcriptional regulator
B4918_RS30430	COG0488	(ABC) transporter
B4918_RS30435	COG1309	transcriptional regulator
B4918_RS30440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B4918_RS30445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B4918_RS30445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B4918_RS30450	COG0628	permease
B4918_RS30470	COG3275	phosphorelay sensor kinase activity
B4918_RS30475	COG2814	Major facilitator Superfamily
B4918_RS30480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B4918_RS30485	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
B4918_RS30520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B4918_RS30525	COG1272	protein, Hemolysin III
B4918_RS30545	COG1164	Oligoendopeptidase f
B4918_RS30560	COG5002	protein histidine kinase activity
B4918_RS30575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B4918_RS30580	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B4918_RS30585	COG4853	Protein conserved in bacteria
B4918_RS30595	COG5002	protein histidine kinase activity
B4918_RS30600	COG0745	RESPONSE REGULATOR receiver
B4918_RS30630	COG0305	Participates in initiation and elongation during chromosome replication
B4918_RS30640	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
B4918_RS30645	COG4241	membrane
B4918_RS30655	COG0629	single-stranded DNA binding
B4918_RS30665	COG0012	GTP binding
B4918_RS30670	COG4481	Protein conserved in bacteria
B4918_RS30675	COG0668	transmembrane transport
B4918_RS30685	COG1475	DNA binding
B4918_RS30690	COG1192	Involved in chromosome partitioning
B4918_RS30715	COG1847	R3H domain protein
B4918_RS30750	COG3331	DNA recombination
B4918_RS30775	COG0582	viral genome integration into host DNA
B4918_RS30790	COG5484	DNA packaging
B4918_RS30795	COG1783	phage Terminase large subunit
B4918_RS30810	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B4918_RS30815	COG4653	Phage capsid family
B4918_RS30925	COG3547	Transposase (IS116 IS110 IS902 family)
B4918_RS30940	COG0457	Tetratricopeptide repeat
B4918_RS31010	COG3620	sequence-specific DNA binding
B4918_RS31145	COG2002	toxin-antitoxin pair type II binding
B4918_RS31310	COG4653	Phage capsid family
B4918_RS31315	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B4918_RS31325	COG2369	cell adhesion
B4918_RS31330	COG5518	Phage portal protein
B4918_RS31345	COG4974	Belongs to the 'phage' integrase family
B4918_RS31350	COG5484	DNA packaging
B4918_RS31415	COG3344	reverse transcriptase
B4918_RS31475	COG3800	Transcriptional regulator
B4918_RS31475	COG1396	sequence-specific DNA binding
B4918_RS31575	COG0582	viral genome integration into host DNA
B4918_RS31580	COG0582	viral genome integration into host DNA
B4918_RS31655	COG0776	regulation of translation
B4918_RS31670	COG0457	Tetratricopeptide repeat
B4918_RS31685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B4918_RS31700	COG0367	asparagine synthase
B4918_RS31705	COG1309	transcriptional regulator
B4918_RS31765	COG0457	Tetratricopeptide repeat
B4918_RS31845	COG1404	Belongs to the peptidase S8 family
B4918_RS31920	COG0592	DNA-directed DNA polymerase activity
B4918_RS31925	COG4712	double-strand break repair protein
B4918_RS31955	COG4282	regulation of fungal-type cell wall biogenesis
B4918_RS32175	COG3344	reverse transcriptase
B4918_RS32235	COG2311	Membrane
B4918_RS32295	COG3118	belongs to the thioredoxin family
B4918_RS32300	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B4918_RS32310	COG0457	Tetratricopeptide repeat
B4918_RS32335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B4918_RS32360	COG1051	belongs to the nudix hydrolase family
B4918_RS32375	COG3344	reverse transcriptase
B4918_RS32405	COG2002	toxin-antitoxin pair type II binding
B4918_RS32410	COG4166	transmembrane transport
B4918_RS32425	COG4974	Belongs to the 'phage' integrase family
B4918_RS32505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B4918_RS32515	COG0840	transmembrane signaling receptor activity
B4918_RS32520	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B4918_RS32530	COG0500	methyltransferase
B4918_RS32535	COG0747	negative chemotaxis
B4918_RS32540	COG0601	transmembrane transport
B4918_RS32550	COG0444	Belongs to the ABC transporter superfamily
B4918_RS32555	COG4608	Belongs to the ABC transporter superfamily
B4918_RS32575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B4918_RS32580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B4918_RS32610	COG1686	Belongs to the peptidase S11 family
B4918_RS32615	COG2814	Major facilitator Superfamily
B4918_RS32620	COG0697	spore germination
B4918_RS32625	COG0726	polysaccharide deacetylase
B4918_RS32650	COG1760	l-serine dehydratase
B4918_RS32655	COG1760	l-serine dehydratase
B4918_RS32660	COG0814	amino acid
B4918_RS32710	COG1533	DNA photolyase activity
B4918_RS32740	COG0745	RESPONSE REGULATOR receiver
B4918_RS32745	COG2205	protein histidine kinase activity
B4918_RS32750	COG1136	(ABC) transporter
B4918_RS32755	COG0577	efflux transmembrane transporter activity
B4918_RS32770	COG0741	lytic transglycosylase activity
B4918_RS32780	COG0772	Belongs to the SEDS family
B4918_RS32790	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
B4918_RS32795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B4918_RS32800	COG0772	Belongs to the SEDS family
B4918_RS32810	COG2239	Acts as a magnesium transporter
B4918_RS32900	COG0586	Pfam SNARE associated Golgi protein
B4918_RS32915	COG2226	methyltransferase
B4918_RS32950	COG3344	reverse transcriptase
B4918_RS32995	COG0490	domain, Protein
B4918_RS33000	COG0475	glutathione-regulated potassium exporter activity
B4918_RS33005	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4918_RS33005	COG3409	Peptidoglycan-binding domain 1 protein
B4918_RS33050	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4918_RS33050	COG3409	Peptidoglycan-binding domain 1 protein
B4918_RS33080	COG4824	toxin secretion phage lysis holin
B4918_RS33110	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B4918_RS33335	COG3344	reverse transcriptase
B4918_RS33365	COG3409	Peptidoglycan-binding domain 1 protein
B4918_RS33365	COG5632	N-Acetylmuramoyl-L-alanine amidase
B4918_RS33655	COG0384	phenazine biosynthesis protein PhzF