locus-tag	class	description
BtBc_RS00010	COG0592	DNA-directed DNA polymerase activity
BtBc_RS00015	COG2501	S4 domain
BtBc_RS00025	COG0187	DNA topoisomerase II activity
BtBc_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BtBc_RS00065	COG0516	GMP reductase activity
BtBc_RS00065	COG0517	IMP dehydrogenase activity
BtBc_RS00070	COG1686	Belongs to the peptidase S11 family
BtBc_RS00100	COG1428	Deoxynucleoside kinase
BtBc_RS00105	COG1428	Deoxynucleoside kinase
BtBc_RS00110	COG1335	isochorismatase
BtBc_RS00115	COG0590	tRNA wobble adenosine to inosine editing
BtBc_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BtBc_RS00180	COG1982	Orn Lys Arg decarboxylase major
BtBc_RS00190	COG0470	DNA polymerase III
BtBc_RS00195	COG1774	PSP1 C-terminal conserved region
BtBc_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BtBc_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BtBc_RS00220	COG2002	toxin-antitoxin pair type II binding
BtBc_RS00230	COG0084	hydrolase, TatD family'
BtBc_RS00250	COG4466	Protein conserved in bacteria
BtBc_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BtBc_RS00270	COG0251	oxidation-reduction process
BtBc_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BtBc_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BtBc_RS00305	COG2002	toxin-antitoxin pair type II binding
BtBc_RS00310	COG2244	polysaccharide biosynthetic process
BtBc_RS00315	COG3956	TIGRFAM MazG family protein
BtBc_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BtBc_RS00340	COG1098	S1 RNA binding domain
BtBc_RS00355	COG2208	phosphoserine phosphatase activity
BtBc_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BtBc_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BtBc_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BtBc_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BtBc_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
BtBc_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BtBc_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BtBc_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BtBc_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BtBc_RS00420	COG1396	sequence-specific DNA binding
BtBc_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BtBc_RS00515	COG3880	PFAM UvrB UvrC protein
BtBc_RS00525	COG0542	response to heat
BtBc_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BtBc_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
BtBc_RS00560	COG1045	serine acetyltransferase
BtBc_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BtBc_RS00580	COG3688	RNA-binding protein containing a PIN domain
BtBc_RS00590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BtBc_RS00595	COG0250	Participates in transcription elongation, termination and antitermination
BtBc_RS00600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BtBc_RS00620	COG2813	Specifically methylates the guanine in position
BtBc_RS00635	COG1358	cellular component organization or biogenesis
BtBc_RS00640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BtBc_RS00705	COG0255	Belongs to the universal ribosomal protein uL29 family
BtBc_RS00765	COG0201	protein transport
BtBc_RS00775	COG0024	Methionine aminopeptidase
BtBc_RS00785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BtBc_RS00820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BtBc_RS00845	COG0860	N-Acetylmuramoyl-L-alanine amidase
BtBc_RS00850	COG0489	protein tyrosine kinase activity
BtBc_RS00860	COG2194	sulfuric ester hydrolase activity
BtBc_RS00865	COG0726	polysaccharide deacetylase
BtBc_RS00945	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BtBc_RS00950	COG4856	YbbR-like protein
BtBc_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS00990	COG2011	ABC-type metal ion transport system permease component
BtBc_RS00995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BtBc_RS01000	COG1464	Belongs to the NlpA lipoprotein family
BtBc_RS01005	COG0604	alcohol dehydrogenase
BtBc_RS01015	COG0277	FAD linked oxidase domain protein
BtBc_RS01020	COG2271	Major facilitator Superfamily
BtBc_RS01030	COG2814	Major facilitator Superfamily
BtBc_RS01045	COG2207	Transcriptional regulator
BtBc_RS01060	COG4166	transmembrane transport
BtBc_RS01065	COG4166	transmembrane transport
BtBc_RS01075	COG0656	L-ascorbic acid biosynthetic process
BtBc_RS01090	COG4149	molybdate abc transporter
BtBc_RS01095	COG0725	ABC transporter, periplasmic molybdate-binding protein
BtBc_RS01100	COG1910	domain protein
BtBc_RS01110	COG0697	spore germination
BtBc_RS01120	COG0204	Acyl-transferase
BtBc_RS01125	COG1609	Transcriptional regulator
BtBc_RS01135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BtBc_RS01155	COG5298	Protein conserved in bacteria
BtBc_RS01175	COG0488	(ABC) transporter
BtBc_RS01185	COG0747	negative chemotaxis
BtBc_RS01205	COG3344	reverse transcriptase
BtBc_RS01215	COG0601	transmembrane transport
BtBc_RS01220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BtBc_RS01225	COG0444	Belongs to the ABC transporter superfamily
BtBc_RS01230	COG4608	Belongs to the ABC transporter superfamily
BtBc_RS01235	COG2801	Transposase and inactivated derivatives
BtBc_RS01245	COG0561	phosphatase activity
BtBc_RS01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BtBc_RS01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
BtBc_RS01290	COG0531	amino acid
BtBc_RS01295	COG2814	Major facilitator Superfamily
BtBc_RS01305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BtBc_RS01315	COG4294	response to UV
BtBc_RS01320	COG0705	Rhomboid family
BtBc_RS01330	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BtBc_RS01335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BtBc_RS01340	COG0864	Transcriptional regulator
BtBc_RS01345	COG2337	Toxic component of a toxin-antitoxin (TA) module
BtBc_RS01350	COG2183	response to ionizing radiation
BtBc_RS01445	COG0802	atpase or kinase
BtBc_RS01450	COG1214	PFAM Peptidase M22, glycoprotease
BtBc_RS01455	COG0456	acetyltransferase
BtBc_RS01465	COG0488	(ABC) transporter
BtBc_RS01480	COG1266	CAAX protease self-immunity
BtBc_RS01495	COG0582	viral genome integration into host DNA
BtBc_RS01515	COG3378	Phage plasmid primase P4 family
BtBc_RS01575	COG0582	viral genome integration into host DNA
BtBc_RS01690	COG0582	viral genome integration into host DNA
BtBc_RS01790	COG4824	toxin secretion phage lysis holin
BtBc_RS01825	COG2252	PERMEase
BtBc_RS01835	COG5002	protein histidine kinase activity
BtBc_RS01860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BtBc_RS01900	COG2205	protein histidine kinase activity
BtBc_RS01905	COG0745	RESPONSE REGULATOR receiver
BtBc_RS01955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BtBc_RS01965	COG0463	Glycosyl transferase, family 2
BtBc_RS01965	COG1216	Glycosyl transferase, family 2
BtBc_RS01990	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BtBc_RS01995	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BtBc_RS02000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BtBc_RS02010	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BtBc_RS02025	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BtBc_RS02035	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BtBc_RS02045	COG0151	Belongs to the GarS family
BtBc_RS02070	COG0210	DNA helicase
BtBc_RS02080	COG4851	CamS sex pheromone cAM373 precursor
BtBc_RS02095	COG1335	isochorismatase
BtBc_RS02105	COG2011	ABC-type metal ion transport system permease component
BtBc_RS02110	COG1464	Belongs to the NlpA lipoprotein family
BtBc_RS02120	COG0003	Pfam Anion-transporting ATPase
BtBc_RS02125	COG1846	Transcriptional regulator
BtBc_RS02130	COG4682	membrane
BtBc_RS02150	COG1597	lipid kinase activity
BtBc_RS02160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BtBc_RS02170	COG1012	belongs to the aldehyde dehydrogenase family
BtBc_RS02175	COG2076	Multidrug Resistance protein
BtBc_RS02185	COG2309	aminopeptidase activity
BtBc_RS02200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BtBc_RS02210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BtBc_RS02215	COG4807	Protein conserved in bacteria
BtBc_RS02245	COG1473	amidohydrolase
BtBc_RS02260	COG0450	alkyl hydroperoxide reductase
BtBc_RS02280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BtBc_RS02285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BtBc_RS02290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BtBc_RS02295	COG0492	ferredoxin-NADP+ reductase activity
BtBc_RS02305	COG0166	Belongs to the GPI family
BtBc_RS02330	COG5002	protein histidine kinase activity
BtBc_RS02350	COG3541	Predicted nucleotidyltransferase
BtBc_RS02355	COG2814	Major facilitator Superfamily
BtBc_RS02360	COG0723	plastoquinol--plastocyanin reductase activity
BtBc_RS02360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BtBc_RS02370	COG0723	plastoquinol--plastocyanin reductase activity
BtBc_RS02370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BtBc_RS02380	COG0765	amino acid transport
BtBc_RS02385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BtBc_RS02395	COG0840	transmembrane signaling receptor activity
BtBc_RS02420	COG0549	Belongs to the carbamate kinase family
BtBc_RS02425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BtBc_RS02450	COG0366	Alpha amylase catalytic
BtBc_RS02455	COG1263	PTS System
BtBc_RS02455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BtBc_RS02455	COG2190	(PTS) system
BtBc_RS02485	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BtBc_RS02505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BtBc_RS02515	COG1116	anion transmembrane transporter activity
BtBc_RS02560	COG2270	Major facilitator Superfamily
BtBc_RS02590	COG2310	stress, protein
BtBc_RS02595	COG2310	stress, protein
BtBc_RS02600	COG2310	stress, protein
BtBc_RS02605	COG0861	Integral membrane protein TerC family
BtBc_RS02615	COG3853	Toxic anion resistance protein (TelA)
BtBc_RS02630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BtBc_RS02640	COG1295	ribonuclease BN
BtBc_RS02645	COG2217	Heavy metal translocating P-type atpase
BtBc_RS02670	COG0586	Pfam SNARE associated Golgi protein
BtBc_RS02685	COG3871	stress protein (general stress protein 26)
BtBc_RS02690	COG0387	Pfam Sodium calcium exchanger
BtBc_RS02700	COG0535	radical SAM domain protein
BtBc_RS02720	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BtBc_RS02725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BtBc_RS02740	COG3829	transcription factor binding
BtBc_RS02750	COG0833	amino acid
BtBc_RS02755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BtBc_RS02780	COG1263	PTS System
BtBc_RS02780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BtBc_RS02785	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BtBc_RS02800	COG0463	Glycosyl transferase, family 2
BtBc_RS02810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BtBc_RS02810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BtBc_RS02825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BtBc_RS02845	COG1228	amidohydrolase
BtBc_RS02850	COG1090	epimerase
BtBc_RS02880	COG1988	membrane-bound metal-dependent
BtBc_RS02885	COG1194	a g-specific adenine glycosylase
BtBc_RS02910	COG1132	(ABC) transporter
BtBc_RS02915	COG4129	membrane
BtBc_RS02920	COG0069	glutamate synthase activity
BtBc_RS02920	COG0067	glutamate synthase
BtBc_RS02920	COG0070	glutamate synthase
BtBc_RS02930	COG4555	ABC transporter
BtBc_RS02950	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BtBc_RS02955	COG0735	belongs to the Fur family
BtBc_RS03075	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BtBc_RS03100	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BtBc_RS03105	COG1716	ATPase activity
BtBc_RS03105	COG5001	Diguanylate cyclase
BtBc_RS03110	COG2766	serine protein kinase
BtBc_RS03125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BtBc_RS03135	COG1585	Membrane protein implicated in regulation of membrane protease activity
BtBc_RS03140	COG2268	Band 7 protein
BtBc_RS03150	COG3290	protein histidine kinase activity
BtBc_RS03155	COG4565	transcriptional regulatory protein
BtBc_RS03160	COG2851	Citrate transporter
BtBc_RS03185	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BtBc_RS03190	COG3842	ATPase activity
BtBc_RS03195	COG1175	transmembrane transport
BtBc_RS03200	COG0395	ABC-type sugar transport system, permease component
BtBc_RS03210	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BtBc_RS03215	COG0745	RESPONSE REGULATOR receiver
BtBc_RS03220	COG3850	Histidine kinase
BtBc_RS03220	COG5002	protein histidine kinase activity
BtBc_RS03230	COG4990	cell redox homeostasis
BtBc_RS03240	COG3290	protein histidine kinase activity
BtBc_RS03245	COG4565	transcriptional regulatory protein
BtBc_RS03250	COG3493	citrate carrier protein
BtBc_RS03255	COG0281	malic enzyme
BtBc_RS03265	COG0697	spore germination
BtBc_RS03270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BtBc_RS03280	COG5002	protein histidine kinase activity
BtBc_RS03285	COG0745	RESPONSE REGULATOR receiver
BtBc_RS03300	COG0454	-acetyltransferase
BtBc_RS03300	COG0456	acetyltransferase
BtBc_RS03305	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BtBc_RS03310	COG3383	formate dehydrogenase (NAD+) activity
BtBc_RS03315	COG2427	Protein of unknown function (DUF1641)
BtBc_RS03330	COG0531	amino acid
BtBc_RS03340	COG0640	Transcriptional regulator
BtBc_RS03345	COG2217	Heavy metal translocating P-type atpase
BtBc_RS03350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BtBc_RS03365	COG3227	Zinc metalloprotease (Elastase)
BtBc_RS03385	COG2720	vancomycin resistance protein
BtBc_RS03390	COG1316	TRANSCRIPTIONal
BtBc_RS03395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BtBc_RS03410	COG3344	reverse transcriptase
BtBc_RS03420	COG0346	lactoylglutathione lyase activity
BtBc_RS03425	COG1253	flavin adenine dinucleotide binding
BtBc_RS03430	COG1027	Aspartate ammonia-lyase
BtBc_RS03435	COG1620	l-lactate permease
BtBc_RS03460	COG3104	oligopeptide transport
BtBc_RS03465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BtBc_RS03470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BtBc_RS03475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BtBc_RS03485	COG2226	methyltransferase
BtBc_RS03495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BtBc_RS03505	COG4548	von Willebrand factor, type A
BtBc_RS03510	COG0714	Associated with various cellular activities
BtBc_RS03530	COG0531	amino acid
BtBc_RS03535	COG2188	Transcriptional regulator
BtBc_RS03540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BtBc_RS03540	COG1263	PTS System
BtBc_RS03545	COG0366	Alpha amylase catalytic
BtBc_RS03560	COG0697	spore germination
BtBc_RS03565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BtBc_RS03570	COG1115	amino acid carrier protein
BtBc_RS03580	COG1126	abc transporter atp-binding protein
BtBc_RS03585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BtBc_RS03590	COG0765	amino acid transport
BtBc_RS03595	COG0765	amino acid transport
BtBc_RS03600	COG0833	amino acid
BtBc_RS03615	COG1595	DNA-templated transcription, initiation
BtBc_RS03625	COG2378	regulation of single-species biofilm formation
BtBc_RS03630	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BtBc_RS03635	COG5002	protein histidine kinase activity
BtBc_RS03665	COG2271	Major facilitator Superfamily
BtBc_RS03670	COG1846	Transcriptional regulator
BtBc_RS03675	COG0477	Major facilitator Superfamily
BtBc_RS03680	COG1609	Transcriptional regulator
BtBc_RS03685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BtBc_RS03700	COG1172	Belongs to the binding-protein-dependent transport system permease family
BtBc_RS03705	COG1879	ABC-type sugar transport system periplasmic component
BtBc_RS03735	COG1063	alcohol dehydrogenase
BtBc_RS03745	COG2801	Transposase and inactivated derivatives
BtBc_RS03775	COG1396	sequence-specific DNA binding
BtBc_RS03855	COG0582	viral genome integration into host DNA
BtBc_RS03905	COG4626	Terminase
BtBc_RS03905	COG1802	Transcriptional regulator
BtBc_RS03915	COG0740	serine-type endopeptidase activity
BtBc_RS04005	COG1674	ftsk spoiiie
BtBc_RS04050	COG0840	transmembrane signaling receptor activity
BtBc_RS04055	COG3583	domain protein
BtBc_RS04055	COG3584	3D domain protein
BtBc_RS04060	COG1476	TRANSCRIPTIONal
BtBc_RS04080	COG3104	oligopeptide transport
BtBc_RS04085	COG1114	Component of the transport system for branched-chain amino acids
BtBc_RS04100	COG1113	amino acid transport
BtBc_RS04105	COG2252	PERMEase
BtBc_RS04120	COG2153	protein acetylation
BtBc_RS04130	COG0475	glutathione-regulated potassium exporter activity
BtBc_RS04130	COG0569	domain protein
BtBc_RS04140	COG1845	cytochrome c oxidase, subunit III
BtBc_RS04145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BtBc_RS04155	COG0833	amino acid
BtBc_RS04160	COG4990	cell redox homeostasis
BtBc_RS04175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BtBc_RS04180	COG0697	spore germination
BtBc_RS04185	COG0531	amino acid
BtBc_RS04195	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BtBc_RS04200	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BtBc_RS04205	COG1918	ferrous iron import across plasma membrane
BtBc_RS04205	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BtBc_RS04210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BtBc_RS04215	COG0573	inorganic phosphate transmembrane transporter activity
BtBc_RS04220	COG0581	inorganic phosphate transmembrane transporter activity
BtBc_RS04225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BtBc_RS04345	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BtBc_RS04365	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BtBc_RS04370	COG1116	anion transmembrane transporter activity
BtBc_RS04375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BtBc_RS04380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BtBc_RS04385	COG0352	thiamine-phosphate diphosphorylase activity
BtBc_RS04390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BtBc_RS04395	COG2104	thiamine diphosphate biosynthetic process
BtBc_RS04405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BtBc_RS04410	COG0351	phosphomethylpyrimidine kinase
BtBc_RS04450	COG2205	protein histidine kinase activity
BtBc_RS04455	COG2814	Major facilitator Superfamily
BtBc_RS04460	COG1846	Transcriptional regulator
BtBc_RS04485	COG1136	(ABC) transporter
BtBc_RS04495	COG2252	PERMEase
BtBc_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS04555	COG2801	Transposase and inactivated derivatives
BtBc_RS04570	COG0778	Nitroreductase
BtBc_RS04575	COG2719	SpoVR family
BtBc_RS04585	COG3591	Belongs to the peptidase S1B family
BtBc_RS04595	COG0446	pyridine nucleotide-disulphide oxidoreductase
BtBc_RS04600	COG1937	Protein conserved in bacteria
BtBc_RS04605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BtBc_RS04605	COG0425	Belongs to the sulfur carrier protein TusA family
BtBc_RS04610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BtBc_RS04610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BtBc_RS04615	COG0425	Belongs to the sulfur carrier protein TusA family
BtBc_RS04630	COG2210	Belongs to the sulfur carrier protein TusA family
BtBc_RS04635	COG0730	response to heat
BtBc_RS04645	COG1316	TRANSCRIPTIONal
BtBc_RS04650	COG0604	alcohol dehydrogenase
BtBc_RS04655	COG1283	sodium-dependent phosphate transmembrane transporter activity
BtBc_RS04670	COG3711	transcriptional antiterminator
BtBc_RS04670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BtBc_RS04675	COG1447	Phosphotransferase system cellobiose-specific component IIA
BtBc_RS04680	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BtBc_RS04705	COG1388	LysM domain
BtBc_RS04705	COG3584	3D domain protein
BtBc_RS04710	COG0577	efflux transmembrane transporter activity
BtBc_RS04715	COG1136	(ABC) transporter
BtBc_RS04725	COG5522	Integral membrane protein (intg_mem_TP0381)
BtBc_RS04740	COG1114	Component of the transport system for branched-chain amino acids
BtBc_RS04745	COG3546	catalase activity
BtBc_RS04780	COG0586	Pfam SNARE associated Golgi protein
BtBc_RS04810	COG0531	amino acid
BtBc_RS04815	COG0475	glutathione-regulated potassium exporter activity
BtBc_RS04825	COG1737	Transcriptional regulator
BtBc_RS04835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BtBc_RS04835	COG1263	PTS System
BtBc_RS04845	COG2259	Doxx family
BtBc_RS04865	COG1522	sequence-specific DNA binding
BtBc_RS04870	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BtBc_RS04870	COG0165	Argininosuccinate lyase
BtBc_RS04875	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS04895	COG1309	transcriptional regulator
BtBc_RS04900	COG2814	Major facilitator Superfamily
BtBc_RS04905	COG1733	regulation of RNA biosynthetic process
BtBc_RS04920	COG4533	DNA binding
BtBc_RS04925	COG2211	Major facilitator Superfamily
BtBc_RS04935	COG0693	protein deglycase activity
BtBc_RS04940	COG0753	catalase activity
BtBc_RS04950	COG0531	amino acid
BtBc_RS04965	COG1012	belongs to the aldehyde dehydrogenase family
BtBc_RS04970	COG1132	(ABC) transporter
BtBc_RS04975	COG1132	(ABC) transporter
BtBc_RS04980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BtBc_RS04985	COG0765	amino acid transport
BtBc_RS04990	COG1126	abc transporter atp-binding protein
BtBc_RS05005	COG0189	ligase activity
BtBc_RS05035	COG0028	Belongs to the TPP enzyme family
BtBc_RS05040	COG3527	Alpha-acetolactate decarboxylase
BtBc_RS05055	COG0561	phosphatase activity
BtBc_RS05065	COG3409	Peptidoglycan-binding domain 1 protein
BtBc_RS05065	COG5632	N-Acetylmuramoyl-L-alanine amidase
BtBc_RS05070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BtBc_RS05075	COG0318	PFAM AMP-dependent synthetase and ligase
BtBc_RS05090	COG0659	secondary active sulfate transmembrane transporter activity
BtBc_RS05095	COG2244	polysaccharide biosynthetic process
BtBc_RS05115	COG1024	Enoyl-CoA hydratase
BtBc_RS05135	COG1363	Peptidase, m42
BtBc_RS05175	COG0601	transmembrane transport
BtBc_RS05180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BtBc_RS05185	COG0444	Belongs to the ABC transporter superfamily
BtBc_RS05190	COG4608	Belongs to the ABC transporter superfamily
BtBc_RS05205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BtBc_RS05225	COG2801	Transposase and inactivated derivatives
BtBc_RS05295	COG0477	Major facilitator Superfamily
BtBc_RS05300	COG3290	protein histidine kinase activity
BtBc_RS05305	COG4565	transcriptional regulatory protein
BtBc_RS05310	COG3181	Tripartite tricarboxylate transporter family receptor
BtBc_RS05315	COG0494	nUDIX hydrolase
BtBc_RS05330	COG0305	Participates in initiation and elongation during chromosome replication
BtBc_RS05345	COG0305	Participates in initiation and elongation during chromosome replication
BtBc_RS05370	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BtBc_RS05375	COG1288	antiporter activity
BtBc_RS05385	COG1842	Phage shock protein A
BtBc_RS05395	COG0477	Major facilitator Superfamily
BtBc_RS05410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS05425	COG2801	Transposase and inactivated derivatives
BtBc_RS05465	COG2020	methyltransferase activity
BtBc_RS05490	COG3344	reverse transcriptase
BtBc_RS05505	COG1073	alpha beta
BtBc_RS05540	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BtBc_RS05545	COG1522	sequence-specific DNA binding
BtBc_RS05560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BtBc_RS05610	COG1183	phosphatidylcholine synthase activity
BtBc_RS05625	COG2801	Transposase and inactivated derivatives
BtBc_RS05630	COG2814	Major facilitator Superfamily
BtBc_RS05635	COG0640	Transcriptional regulator
BtBc_RS05660	COG2376	Dihydroxyacetone kinase
BtBc_RS05670	COG2376	Dihydroxyacetone kinase
BtBc_RS05710	COG2373	Large extracellular alpha-helical protein
BtBc_RS05780	COG1191	sigma factor activity
BtBc_RS05790	COG2208	phosphoserine phosphatase activity
BtBc_RS05795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BtBc_RS05800	COG5002	protein histidine kinase activity
BtBc_RS05800	COG0784	Response regulator, receiver
BtBc_RS05800	COG2205	protein histidine kinase activity
BtBc_RS05835	COG2186	Transcriptional regulator
BtBc_RS05845	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BtBc_RS05865	COG0420	3'-5' exonuclease activity
BtBc_RS05870	COG4717	serine-type aminopeptidase activity
BtBc_RS05895	COG0346	lactoylglutathione lyase activity
BtBc_RS05900	COG0346	lactoylglutathione lyase activity
BtBc_RS05905	COG0457	Tetratricopeptide repeat
BtBc_RS05930	COG2140	Oxalate decarboxylase
BtBc_RS05935	COG3620	sequence-specific DNA binding
BtBc_RS05940	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BtBc_RS05945	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BtBc_RS05955	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BtBc_RS05970	COG1595	DNA-templated transcription, initiation
BtBc_RS05980	COG0772	Belongs to the SEDS family
BtBc_RS05985	COG3973	AAA domain
BtBc_RS06010	COG4980	gas vesicle protein
BtBc_RS06015	COG0537	adenosine 5'-monophosphoramidase activity
BtBc_RS06020	COG1131	(ABC) transporter
BtBc_RS06025	COG4473	ABC transporter
BtBc_RS06035	COG1309	transcriptional regulator
BtBc_RS06045	COG3402	PFAM membrane-flanked domain
BtBc_RS06050	COG3428	Bacterial PH domain
BtBc_RS06085	COG0697	spore germination
BtBc_RS06090	COG3402	PFAM membrane-flanked domain
BtBc_RS06095	COG3428	Bacterial PH domain
BtBc_RS06100	COG2329	Antibiotic biosynthesis monooxygenase
BtBc_RS06105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BtBc_RS06120	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BtBc_RS06155	COG1309	transcriptional regulator
BtBc_RS06160	COG1511	domain protein
BtBc_RS06160	COG1511	domain protein
BtBc_RS06190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS06195	COG1609	Transcriptional regulator
BtBc_RS06205	COG1234	tRNA 3'-trailer cleavage
BtBc_RS06210	COG0095	Lipoate-protein ligase
BtBc_RS06220	COG0318	PFAM AMP-dependent synthetase and ligase
BtBc_RS06230	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BtBc_RS06240	COG4208	sulfate ABC transporter
BtBc_RS06330	COG1073	alpha beta
BtBc_RS06335	COG1408	metallophosphoesterase
BtBc_RS06340	COG1078	dGTPase activity
BtBc_RS06350	COG1595	DNA-templated transcription, initiation
BtBc_RS06355	COG3708	Transcriptional regulator
BtBc_RS06355	COG2207	Transcriptional regulator
BtBc_RS06370	COG0745	RESPONSE REGULATOR receiver
BtBc_RS06390	COG0501	Belongs to the peptidase M48B family
BtBc_RS06395	COG0840	transmembrane signaling receptor activity
BtBc_RS06400	COG3693	PFAM glycoside hydrolase, family 10
BtBc_RS06410	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BtBc_RS06415	COG2224	Isocitrate lyase
BtBc_RS06430	COG1278	Cold shock
BtBc_RS06450	COG0398	Pfam SNARE associated Golgi protein
BtBc_RS06510	COG0179	Fumarylacetoacetate (FAA) hydrolase
BtBc_RS06535	COG0367	asparagine synthase
BtBc_RS06550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BtBc_RS06645	COG3331	DNA recombination
BtBc_RS06665	COG3547	Transposase (IS116 IS110 IS902 family)
BtBc_RS06700	COG3547	Transposase (IS116 IS110 IS902 family)
BtBc_RS06770	COG4824	toxin secretion phage lysis holin
BtBc_RS06775	COG3409	Peptidoglycan-binding domain 1 protein
BtBc_RS06775	COG1388	LysM domain
BtBc_RS06775	COG5632	N-Acetylmuramoyl-L-alanine amidase
BtBc_RS06800	COG0367	asparagine synthase
BtBc_RS06810	COG0753	catalase activity
BtBc_RS06820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BtBc_RS06840	COG3339	Conserved Protein
BtBc_RS06845	COG0004	ammonium transporteR
BtBc_RS06865	COG2996	Protein conserved in bacteria
BtBc_RS06885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BtBc_RS06900	COG0561	phosphatase activity
BtBc_RS06920	COG2267	carboxylic ester hydrolase activity
BtBc_RS06935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BtBc_RS06940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BtBc_RS06945	COG5504	Zn-dependent protease
BtBc_RS06955	COG0180	Tryptophanyl-tRNA synthetase
BtBc_RS06970	COG4166	transmembrane transport
BtBc_RS06975	COG0601	transmembrane transport
BtBc_RS06980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BtBc_RS06985	COG0444	Belongs to the ABC transporter superfamily
BtBc_RS06990	COG4608	Belongs to the ABC transporter superfamily
BtBc_RS06995	COG0534	Mate efflux family protein
BtBc_RS07000	COG4166	transmembrane transport
BtBc_RS07015	COG0861	Integral membrane protein TerC family
BtBc_RS07025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BtBc_RS07035	COG1164	Oligoendopeptidase f
BtBc_RS07045	COG2346	COG2346, Truncated hemoglobins
BtBc_RS07050	COG4116	CYTH
BtBc_RS07060	COG2357	RelA SpoT domain protein
BtBc_RS07070	COG0564	pseudouridine synthase activity
BtBc_RS07085	COG0772	Belongs to the SEDS family
BtBc_RS07090	COG1216	Glycosyl transferase, family 2
BtBc_RS07110	COG0463	Glycosyl transferase, family 2
BtBc_RS07110	COG0457	Tetratricopeptide repeat
BtBc_RS07130	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BtBc_RS07145	COG1091	dTDP-4-dehydrorhamnose reductase activity
BtBc_RS07190	COG2153	protein acetylation
BtBc_RS07200	COG2382	esterase
BtBc_RS07225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BtBc_RS07235	COG0512	Glutamine amidotransferase of anthranilate synthase
BtBc_RS07235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BtBc_RS07270	COG1620	l-lactate permease
BtBc_RS07275	COG5634	Uncharacterized conserved protein (DUF2278)
BtBc_RS07320	COG2801	Transposase and inactivated derivatives
BtBc_RS07325	COG2226	methyltransferase
BtBc_RS07345	COG0508	dehydrogenase complex catalyzes the overall conversion of
BtBc_RS07355	COG1476	TRANSCRIPTIONal
BtBc_RS07385	COG2801	Transposase and inactivated derivatives
BtBc_RS07400	COG4152	abc transporter atp-binding protein
BtBc_RS07405	COG1668	transmembrane transport
BtBc_RS07425	COG2226	methyltransferase
BtBc_RS07435	COG1686	Belongs to the peptidase S11 family
BtBc_RS07440	COG0681	Belongs to the peptidase S26 family
BtBc_RS07475	COG1012	belongs to the aldehyde dehydrogenase family
BtBc_RS07485	COG1176	ABC-type spermidine putrescine transport system, permease component I
BtBc_RS07490	COG1177	transmembrane transport
BtBc_RS07505	COG2409	Drug exporters of the RND superfamily
BtBc_RS07515	COG0564	pseudouridine synthase activity
BtBc_RS07525	COG2340	Cysteine-rich secretory protein family
BtBc_RS07530	COG0247	lactate metabolic process
BtBc_RS07535	COG0277	FAD linked oxidase domain protein
BtBc_RS07540	COG3835	regulator
BtBc_RS07550	COG0745	RESPONSE REGULATOR receiver
BtBc_RS07555	COG5002	protein histidine kinase activity
BtBc_RS07560	COG2186	Transcriptional regulator
BtBc_RS07580	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BtBc_RS07590	COG2116	formate transmembrane transporter activity
BtBc_RS07595	COG0861	Integral membrane protein TerC family
BtBc_RS07600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BtBc_RS07610	COG2030	dehydratase
BtBc_RS07630	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS07635	COG3243	poly(R)-hydroxyalkanoic acid synthase
BtBc_RS07645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BtBc_RS07660	COG1840	ABC-type Fe3 transport system, periplasmic component
BtBc_RS07665	COG3842	ATPase activity
BtBc_RS07690	COG1349	DNA-binding transcription factor activity
BtBc_RS07705	COG0235	Class ii aldolase
BtBc_RS07715	COG2861	carbohydrate metabolic process
BtBc_RS07725	COG3852	Histidine kinase
BtBc_RS07730	COG1846	Transcriptional regulator
BtBc_RS07740	COG2318	DinB family
BtBc_RS07750	COG5002	protein histidine kinase activity
BtBc_RS07760	COG0720	synthase
BtBc_RS07775	COG4873	Protein conserved in bacteria
BtBc_RS07805	COG1780	Probably involved in ribonucleotide reductase function
BtBc_RS07810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BtBc_RS07815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BtBc_RS07820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BtBc_RS07825	COG1725	Transcriptional regulator
BtBc_RS07830	COG1131	(ABC) transporter
BtBc_RS07840	COG1131	(ABC) transporter
BtBc_RS07860	COG1522	sequence-specific DNA binding
BtBc_RS07870	COG1335	isochorismatase
BtBc_RS07880	COG1619	proteins homologs of microcin C7 resistance protein MccF
BtBc_RS07885	COG2070	2-Nitropropane dioxygenase
BtBc_RS07890	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BtBc_RS07900	COG1696	Membrane protein involved in D-alanine export
BtBc_RS07925	COG0716	FMN binding
BtBc_RS07975	COG1846	Transcriptional regulator
BtBc_RS07985	COG1301	dicarboxylic acid transport
BtBc_RS07990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BtBc_RS07995	COG4709	membrane
BtBc_RS08000	COG3874	Sporulation protein YtfJ
BtBc_RS08020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BtBc_RS08025	COG0028	Belongs to the TPP enzyme family
BtBc_RS08030	COG0440	acetolactate synthase activity
BtBc_RS08105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BtBc_RS08120	COG1183	phosphatidylcholine synthase activity
BtBc_RS08125	COG1368	sulfuric ester hydrolase activity
BtBc_RS08135	COG0019	diaminopimelate decarboxylase activity
BtBc_RS08155	COG0529	Catalyzes the synthesis of activated sulfate
BtBc_RS08160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BtBc_RS08180	COG1648	precorrin-2 dehydrogenase activity
BtBc_RS08185	COG0733	neurotransmitter:sodium symporter activity
BtBc_RS08205	COG1757	Na H antiporter
BtBc_RS08220	COG4758	membrane
BtBc_RS08225	COG4585	Histidine kinase
BtBc_RS08230	COG2197	response regulator
BtBc_RS08240	COG1114	Component of the transport system for branched-chain amino acids
BtBc_RS08290	COG0730	response to heat
BtBc_RS08295	COG0306	phosphate transporter
BtBc_RS08300	COG1392	Phosphate transport regulator
BtBc_RS08305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BtBc_RS08320	COG3852	Histidine kinase
BtBc_RS08325	COG1801	Protein of unknown function DUF72
BtBc_RS08335	COG0582	viral genome integration into host DNA
BtBc_RS08340	COG5002	protein histidine kinase activity
BtBc_RS08355	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BtBc_RS08355	COG0392	lysyltransferase activity
BtBc_RS08370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BtBc_RS08375	COG1686	Belongs to the peptidase S11 family
BtBc_RS08380	COG2715	membrane protein required for spore maturation
BtBc_RS08385	COG0700	Nucleoside recognition
BtBc_RS08390	COG1187	pseudouridine synthase activity
BtBc_RS08400	COG1333	cytochrome c biogenesis protein
BtBc_RS08405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BtBc_RS08410	COG0745	RESPONSE REGULATOR receiver
BtBc_RS08415	COG5002	protein histidine kinase activity
BtBc_RS08420	COG2096	Adenosyltransferase
BtBc_RS08435	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BtBc_RS08440	COG1141	Ferredoxin
BtBc_RS08450	COG0514	ATP-dependent DNA helicase (RecQ)
BtBc_RS08455	COG1266	CAAX protease self-immunity
BtBc_RS08465	COG1408	metallophosphoesterase
BtBc_RS08470	COG0789	Transcriptional regulator
BtBc_RS08480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BtBc_RS08500	COG0492	ferredoxin-NADP+ reductase activity
BtBc_RS08505	COG0252	asparaginase activity
BtBc_RS08570	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BtBc_RS08585	COG0142	geranyltranstransferase activity
BtBc_RS08595	COG0142	geranyltranstransferase activity
BtBc_RS08625	COG0457	Tetratricopeptide repeat
BtBc_RS08645	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BtBc_RS08650	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BtBc_RS08650	COG2010	Cytochrome c
BtBc_RS08655	COG4347	Protein of unknown function (DUF1405)
BtBc_RS08670	COG2738	Putative neutral zinc metallopeptidase
BtBc_RS08680	COG2801	Transposase and inactivated derivatives
BtBc_RS08690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BtBc_RS08695	COG1694	Mazg nucleotide pyrophosphohydrolase
BtBc_RS08715	COG0438	transferase activity, transferring glycosyl groups
BtBc_RS08750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BtBc_RS08750	COG1199	ATP-dependent helicase activity
BtBc_RS08770	COG3935	DnaD domain protein
BtBc_RS08775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BtBc_RS08785	COG4499	WXG100 protein secretion system (Wss), protein YukC
BtBc_RS08785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BtBc_RS08840	COG0116	Belongs to the methyltransferase superfamily
BtBc_RS08850	COG1199	ATP-dependent helicase activity
BtBc_RS08855	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BtBc_RS08865	COG0024	Methionine aminopeptidase
BtBc_RS08875	COG2233	PERMEase
BtBc_RS08880	COG2311	Membrane
BtBc_RS08885	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BtBc_RS08895	COG0456	acetyltransferase
BtBc_RS08945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BtBc_RS08960	COG3944	biosynthesis protein
BtBc_RS08970	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BtBc_RS08985	COG1215	transferase activity, transferring glycosyl groups
BtBc_RS08990	COG0438	transferase activity, transferring glycosyl groups
BtBc_RS09005	COG0454	-acetyltransferase
BtBc_RS09025	COG0328	RNA-DNA hybrid ribonuclease activity
BtBc_RS09060	COG3403	YqcI/YcgG family
BtBc_RS09065	COG1280	lysine exporter protein (LysE YggA)
BtBc_RS09085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BtBc_RS09090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BtBc_RS09100	COG0475	glutathione-regulated potassium exporter activity
BtBc_RS09105	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BtBc_RS09110	COG4978	Transcriptional regulator
BtBc_RS09110	COG0789	Transcriptional regulator
BtBc_RS09120	COG2323	membrane
BtBc_RS09125	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BtBc_RS09165	COG1923	regulation of RNA biosynthetic process
BtBc_RS09175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BtBc_RS09180	COG1360	Flagellar Motor Protein
BtBc_RS09185	COG2201	protein-glutamate methylesterase activity
BtBc_RS09190	COG2198	Histidine kinase
BtBc_RS09190	COG0643	Histidine kinase
BtBc_RS09195	COG1776	CheC inhibitor of MCP methylation
BtBc_RS09195	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BtBc_RS09210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BtBc_RS09230	COG1256	bacterial-type flagellum assembly
BtBc_RS09235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BtBc_RS09255	COG1815	bacterial-type flagellum-dependent cell motility
BtBc_RS09260	COG1558	bacterial-type flagellum-dependent cell motility
BtBc_RS09270	COG1766	The M ring may be actively involved in energy transduction
BtBc_RS09275	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BtBc_RS09285	COG1157	protein secretion by the type III secretion system
BtBc_RS09320	COG0835	chemotaxis
BtBc_RS09320	COG0784	Response regulator, receiver
BtBc_RS09330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BtBc_RS09335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BtBc_RS09340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BtBc_RS09345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BtBc_RS09350	COG0741	lytic transglycosylase activity
BtBc_RS09360	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BtBc_RS09365	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BtBc_RS09365	COG1776	CheC inhibitor of MCP methylation
BtBc_RS09375	COG1338	Plays a role in the flagellum-specific transport system
BtBc_RS09380	COG1987	bacterial-type flagellum assembly
BtBc_RS09390	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BtBc_RS09395	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BtBc_RS09400	COG1419	protein localization to endoplasmic reticulum
BtBc_RS09405	COG4786	Flagellar basal body rod
BtBc_RS09410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BtBc_RS09470	COG0583	DNA-binding transcription factor activity
BtBc_RS09475	COG3842	ATPase activity
BtBc_RS09480	COG0725	ABC transporter, periplasmic molybdate-binding protein
BtBc_RS09515	COG0406	alpha-ribazole phosphatase activity
BtBc_RS09530	COG3547	Transposase (IS116 IS110 IS902 family)
BtBc_RS09550	COG0367	asparagine synthase
BtBc_RS09580	COG1802	Transcriptional regulator
BtBc_RS09585	COG0697	spore germination
BtBc_RS09595	COG0523	cobalamin synthesis protein
BtBc_RS09600	COG0701	Predicted permease
BtBc_RS09615	COG1757	Na H antiporter
BtBc_RS09620	COG0789	Transcriptional regulator
BtBc_RS09645	COG0534	Mate efflux family protein
BtBc_RS09650	COG3340	Belongs to the peptidase S51 family
BtBc_RS09670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BtBc_RS09690	COG2733	membrane
BtBc_RS09725	COG1131	(ABC) transporter
BtBc_RS09745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BtBc_RS09750	COG0528	UMP kinase activity
BtBc_RS09765	COG1027	Aspartate ammonia-lyase
BtBc_RS09770	COG0281	malic enzyme
BtBc_RS09775	COG4191	Histidine kinase
BtBc_RS09780	COG0784	Response regulator, receiver
BtBc_RS09785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BtBc_RS09805	COG2801	Transposase and inactivated derivatives
BtBc_RS09815	COG3620	sequence-specific DNA binding
BtBc_RS09850	COG2814	Major facilitator Superfamily
BtBc_RS09865	COG1695	Transcriptional regulator
BtBc_RS09875	COG0477	Major facilitator Superfamily
BtBc_RS09885	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BtBc_RS09890	COG2223	nitrite transmembrane transporter activity
BtBc_RS09895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BtBc_RS09915	COG0733	neurotransmitter:sodium symporter activity
BtBc_RS09920	COG5566	PFAM Mor transcription activator
BtBc_RS09925	COG2323	membrane
BtBc_RS09945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BtBc_RS09955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BtBc_RS09960	COG0028	Belongs to the TPP enzyme family
BtBc_RS09980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BtBc_RS10005	COG2814	Major facilitator Superfamily
BtBc_RS10010	COG3384	dioxygenase
BtBc_RS10020	COG3279	Response regulator of the LytR AlgR family
BtBc_RS10025	COG0427	acetyl-CoA hydrolase
BtBc_RS10045	COG4166	transmembrane transport
BtBc_RS10050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS10055	COG1914	H( )-stimulated, divalent metal cation uptake system
BtBc_RS10070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BtBc_RS10080	COG0531	amino acid
BtBc_RS10115	COG1309	transcriptional regulator
BtBc_RS10120	COG2390	Transcriptional regulator
BtBc_RS10130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BtBc_RS10135	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BtBc_RS10150	COG4846	Membrane protein involved in cytochrome C biogenesis
BtBc_RS10160	COG0006	proline dipeptidase activity
BtBc_RS10170	COG2132	Multicopper oxidase
BtBc_RS10180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BtBc_RS10200	COG1114	Component of the transport system for branched-chain amino acids
BtBc_RS10210	COG1276	copper resistance
BtBc_RS10210	COG2372	response to copper ion
BtBc_RS10215	COG4549	nuclear export factor GLE1
BtBc_RS10220	COG0697	spore germination
BtBc_RS10225	COG0583	DNA-binding transcription factor activity
BtBc_RS10230	COG1959	2 iron, 2 sulfur cluster binding
BtBc_RS10235	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BtBc_RS10240	COG0778	Nitroreductase
BtBc_RS10255	COG0628	permease
BtBc_RS10265	COG1231	oxidoreductase activity
BtBc_RS10270	COG0523	cobalamin synthesis protein
BtBc_RS10280	COG0411	ABC transporter
BtBc_RS10300	COG0583	DNA-binding transcription factor activity
BtBc_RS10310	COG1942	4-Oxalocrotonate Tautomerase
BtBc_RS10325	COG1271	oxidase subunit
BtBc_RS10330	COG1294	oxidase, subunit
BtBc_RS10335	COG4988	ABC transporter
BtBc_RS10340	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BtBc_RS10350	COG1216	Glycosyl transferase, family 2
BtBc_RS10390	COG1686	Belongs to the peptidase S11 family
BtBc_RS10405	COG1388	LysM domain
BtBc_RS10405	COG0791	NLP P60 protein
BtBc_RS10415	COG1132	(ABC) transporter
BtBc_RS10420	COG0745	RESPONSE REGULATOR receiver
BtBc_RS10425	COG5002	protein histidine kinase activity
BtBc_RS10430	COG0300	oxidoreductase activity
BtBc_RS10460	COG3547	Transposase (IS116 IS110 IS902 family)
BtBc_RS10465	COG0460	homoserine dehydrogenase
BtBc_RS10490	COG1316	TRANSCRIPTIONal
BtBc_RS10500	COG0745	RESPONSE REGULATOR receiver
BtBc_RS10505	COG5002	protein histidine kinase activity
BtBc_RS10520	COG1285	pathogenesis
BtBc_RS10525	COG1247	-acetyltransferase
BtBc_RS10570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BtBc_RS10580	COG1082	Xylose isomerase domain protein TIM barrel
BtBc_RS10590	COG2814	Major facilitator Superfamily
BtBc_RS10595	COG1279	arginine transmembrane transporter activity
BtBc_RS10600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BtBc_RS10610	COG1752	Esterase of the alpha-beta hydrolase superfamily
BtBc_RS10645	COG0577	efflux transmembrane transporter activity
BtBc_RS10650	COG2002	toxin-antitoxin pair type II binding
BtBc_RS10655	COG1404	Belongs to the peptidase S8 family
BtBc_RS10660	COG0640	Transcriptional regulator
BtBc_RS10665	COG0667	Aldo Keto reductase
BtBc_RS10670	COG2814	Major facilitator Superfamily
BtBc_RS10680	COG3152	Membrane
BtBc_RS10705	COG0840	transmembrane signaling receptor activity
BtBc_RS10720	COG3949	Membrane
BtBc_RS10725	COG0783	Belongs to the Dps family
BtBc_RS10740	COG2801	Transposase and inactivated derivatives
BtBc_RS10750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BtBc_RS10760	COG1231	oxidoreductase activity
BtBc_RS10765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS10770	COG4989	oxidoreductase activity
BtBc_RS10780	COG0523	cobalamin synthesis protein
BtBc_RS10785	COG0456	acetyltransferase
BtBc_RS10790	COG0803	Belongs to the bacterial solute-binding protein 9 family
BtBc_RS10810	COG3344	reverse transcriptase
BtBc_RS10820	COG0702	epimerase
BtBc_RS10830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BtBc_RS10840	COG4166	transmembrane transport
BtBc_RS10865	COG5337	Spore coat protein CotH
BtBc_RS10870	COG1051	belongs to the nudix hydrolase family
BtBc_RS10875	COG0586	Pfam SNARE associated Golgi protein
BtBc_RS10880	COG2244	polysaccharide biosynthetic process
BtBc_RS10890	COG0701	Predicted permease
BtBc_RS10895	COG3689	TIGRFAM TIGR03943 family protein
BtBc_RS10900	COG1607	acyl-coa hydrolase
BtBc_RS10905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BtBc_RS10920	COG0702	epimerase
BtBc_RS10925	COG2839	Protein conserved in bacteria
BtBc_RS10930	COG1253	flavin adenine dinucleotide binding
BtBc_RS10945	COG2801	Transposase and inactivated derivatives
BtBc_RS10950	COG2963	transposase activity
BtBc_RS10955	COG1114	Component of the transport system for branched-chain amino acids
BtBc_RS10960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BtBc_RS10975	COG0860	N-Acetylmuramoyl-L-alanine amidase
BtBc_RS10985	COG1876	peptidase activity
BtBc_RS11000	COG2211	Major facilitator Superfamily
BtBc_RS11015	COG0860	N-Acetylmuramoyl-L-alanine amidase
BtBc_RS11025	COG0561	phosphatase activity
BtBc_RS11055	COG3646	Phage regulatory protein
BtBc_RS11130	COG0582	viral genome integration into host DNA
BtBc_RS11180	COG1802	Transcriptional regulator
BtBc_RS11180	COG4626	Terminase
BtBc_RS11190	COG0740	serine-type endopeptidase activity
BtBc_RS11240	COG3344	reverse transcriptase
BtBc_RS11275	COG3547	Transposase (IS116 IS110 IS902 family)
BtBc_RS11325	COG0561	phosphatase activity
BtBc_RS11340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BtBc_RS11350	COG1819	glycosyl
BtBc_RS11355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BtBc_RS11360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BtBc_RS11390	COG0456	acetyltransferase
BtBc_RS11430	COG4499	WXG100 protein secretion system (Wss), protein YukC
BtBc_RS11525	COG3874	Sporulation protein YtfJ
BtBc_RS11550	COG2226	methyltransferase
BtBc_RS11570	COG1082	Xylose isomerase domain protein TIM barrel
BtBc_RS11575	COG0346	lactoylglutathione lyase activity
BtBc_RS11585	COG0604	alcohol dehydrogenase
BtBc_RS11595	COG1595	DNA-templated transcription, initiation
BtBc_RS11610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BtBc_RS11610	COG0426	domain, Protein
BtBc_RS11625	COG0386	Belongs to the glutathione peroxidase family
BtBc_RS11630	COG1305	Transglutaminase-like
BtBc_RS11635	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BtBc_RS11640	COG0714	Associated with various cellular activities
BtBc_RS11650	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BtBc_RS11655	COG1140	nitrate reductase beta subunit
BtBc_RS11660	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BtBc_RS11665	COG2181	nitrate reductase activity
BtBc_RS11670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BtBc_RS11675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BtBc_RS11680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BtBc_RS11685	COG0303	'Molybdopterin
BtBc_RS11690	COG0314	molybdopterin synthase activity
BtBc_RS11695	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BtBc_RS11700	COG2223	nitrite transmembrane transporter activity
BtBc_RS11710	COG1648	precorrin-2 dehydrogenase activity
BtBc_RS11720	COG1587	Uroporphyrinogen-III synthase
BtBc_RS11720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BtBc_RS11725	COG2146	nitrite reductase [NAD(P)H] activity
BtBc_RS11730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BtBc_RS11735	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BtBc_RS11770	COG2359	stage V sporulation protein S
BtBc_RS11795	COG0730	response to heat
BtBc_RS11820	COG0457	Tetratricopeptide repeat
BtBc_RS11835	COG1418	mRNA catabolic process
BtBc_RS11840	COG0488	(ABC) transporter
BtBc_RS11950	COG0629	single-stranded DNA binding
BtBc_RS11960	COG1413	lyase activity
BtBc_RS11975	COG2136	Putative SAM-dependent methyltransferase
BtBc_RS11975	COG2521	methyltransferase
BtBc_RS11980	COG0018	arginyl-trna synthetase
BtBc_RS12025	COG2801	Transposase and inactivated derivatives
BtBc_RS12030	COG2963	transposase activity
BtBc_RS12040	COG0017	Asparaginyl-tRNA synthetase
BtBc_RS12045	COG0733	neurotransmitter:sodium symporter activity
BtBc_RS12070	COG2610	gluconate transmembrane transporter activity
BtBc_RS12080	COG1794	racemase activity, acting on amino acids and derivatives
BtBc_RS12090	COG0456	acetyltransferase
BtBc_RS12100	COG3655	Transcriptional regulator
BtBc_RS12105	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BtBc_RS12115	COG1131	(ABC) transporter
BtBc_RS12120	COG4473	ABC transporter
BtBc_RS12130	COG0546	phosphoglycolate phosphatase activity
BtBc_RS12145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BtBc_RS12160	COG0768	penicillin binding
BtBc_RS12170	COG0204	Acyl-transferase
BtBc_RS12175	COG1272	protein, Hemolysin III
BtBc_RS12185	COG0805	protein transport
BtBc_RS12195	COG1307	EDD domain protein, DegV family
BtBc_RS12205	COG1999	signal sequence binding
BtBc_RS12210	COG0071	Belongs to the small heat shock protein (HSP20) family
BtBc_RS12215	COG0367	asparagine synthase
BtBc_RS12235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BtBc_RS12240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BtBc_RS12260	COG1335	isochorismatase
BtBc_RS12270	COG0668	transmembrane transport
BtBc_RS12275	COG4585	Histidine kinase
BtBc_RS12275	COG2203	Gaf domain
BtBc_RS12280	COG2197	response regulator
BtBc_RS12285	COG1737	Transcriptional regulator
BtBc_RS12290	COG0384	phenazine biosynthesis protein PhzF
BtBc_RS12295	COG1064	alcohol dehydrogenase
BtBc_RS12320	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BtBc_RS12355	COG1125	glycine betaine transport
BtBc_RS12355	COG0517	IMP dehydrogenase activity
BtBc_RS12360	COG1174	glycine betaine transport
BtBc_RS12395	COG1253	flavin adenine dinucleotide binding
BtBc_RS12400	COG1012	belongs to the aldehyde dehydrogenase family
BtBc_RS12405	COG5506	Protein of unknown function (DUF1694)
BtBc_RS12420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BtBc_RS12425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BtBc_RS12430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BtBc_RS12435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BtBc_RS12440	COG0456	acetyltransferase
BtBc_RS12445	COG3829	transcription factor binding
BtBc_RS12450	COG1509	lysine 2,3-aminomutase activity
BtBc_RS12480	COG0515	serine threonine protein kinase
BtBc_RS12480	COG3064	Membrane
BtBc_RS12480	COG4991	sh3 domain protein
BtBc_RS12490	COG0671	phosphoesterase, PA-phosphatase related
BtBc_RS12495	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BtBc_RS12500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BtBc_RS12580	COG0300	oxidoreductase activity
BtBc_RS12600	COG4499	WXG100 protein secretion system (Wss), protein YukC
BtBc_RS12600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BtBc_RS12610	COG2814	Major facilitator Superfamily
BtBc_RS12615	COG4841	protein insertion into membrane
BtBc_RS12620	COG0372	Belongs to the citrate synthase family
BtBc_RS12625	COG2079	MmgE PrpD family protein
BtBc_RS12630	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BtBc_RS12635	COG1960	acyl-CoA dehydrogenase activity
BtBc_RS12640	COG2084	Dehydrogenase
BtBc_RS12650	COG1280	lysine exporter protein (LysE YggA)
BtBc_RS12655	COG1024	Enoyl-CoA hydratase
BtBc_RS12670	COG0420	3'-5' exonuclease activity
BtBc_RS12675	COG0419	ATPase involved in DNA repair
BtBc_RS12695	COG2223	nitrite transmembrane transporter activity
BtBc_RS12700	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS12705	COG1169	isochorismate synthase
BtBc_RS12710	COG1021	2,3-dihydroxybenzoate-AMP ligase
BtBc_RS12715	COG3433	isochorismatase activity
BtBc_RS12715	COG1535	isochorismatase
BtBc_RS12720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BtBc_RS12725	COG3251	PFAM MbtH domain protein
BtBc_RS12730	COG2814	Major facilitator Superfamily
BtBc_RS12745	COG0776	regulation of translation
BtBc_RS12755	COG2318	DinB family
BtBc_RS12765	COG1115	amino acid carrier protein
BtBc_RS12780	COG2329	Antibiotic biosynthesis monooxygenase
BtBc_RS12785	COG1187	pseudouridine synthase activity
BtBc_RS12790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BtBc_RS12795	COG1136	(ABC) transporter
BtBc_RS12805	COG0028	Belongs to the TPP enzyme family
BtBc_RS12845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BtBc_RS12870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BtBc_RS12905	COG1247	-acetyltransferase
BtBc_RS12930	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BtBc_RS12940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS12970	COG0583	DNA-binding transcription factor activity
BtBc_RS12975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BtBc_RS12995	COG0583	DNA-binding transcription factor activity
BtBc_RS13000	COG2258	MOSC domain
BtBc_RS13015	COG1132	(ABC) transporter
BtBc_RS13020	COG1132	(ABC) transporter
BtBc_RS13045	COG1396	sequence-specific DNA binding
BtBc_RS13075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BtBc_RS13080	COG1595	DNA-templated transcription, initiation
BtBc_RS13105	COG1649	PFAM Uncharacterised BCR, COG1649
BtBc_RS13125	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BtBc_RS13130	COG2971	BadF BadG BcrA BcrD
BtBc_RS13150	COG1846	Transcriptional regulator
BtBc_RS13170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BtBc_RS13190	COG1309	transcriptional regulator
BtBc_RS13205	COG0500	methyltransferase
BtBc_RS13205	COG3615	Tellurite resistance protein tehB
BtBc_RS13215	COG2226	methyltransferase
BtBc_RS13220	COG3961	Belongs to the TPP enzyme family
BtBc_RS13225	COG1846	Transcriptional regulator
BtBc_RS13255	COG2195	Cleaves the N-terminal amino acid of tripeptides
BtBc_RS13280	COG2002	toxin-antitoxin pair type II binding
BtBc_RS13285	COG2963	transposase activity
BtBc_RS13290	COG2801	Transposase and inactivated derivatives
BtBc_RS13300	COG0730	response to heat
BtBc_RS13305	COG0110	maltose O-acetyltransferase activity
BtBc_RS13310	COG1686	Belongs to the peptidase S11 family
BtBc_RS13320	COG2814	Major facilitator Superfamily
BtBc_RS13350	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS13380	COG0741	lytic transglycosylase activity
BtBc_RS13390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS13395	COG2239	Acts as a magnesium transporter
BtBc_RS13470	COG3409	Peptidoglycan-binding domain 1 protein
BtBc_RS13470	COG5632	N-Acetylmuramoyl-L-alanine amidase
BtBc_RS13480	COG3831	ATPase activity
BtBc_RS13510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BtBc_RS13540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BtBc_RS13550	COG5002	protein histidine kinase activity
BtBc_RS13550	COG3850	Histidine kinase
BtBc_RS13555	COG0577	efflux transmembrane transporter activity
BtBc_RS13575	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BtBc_RS13585	COG1690	Belongs to the RtcB family
BtBc_RS13595	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BtBc_RS13615	COG2814	Major facilitator Superfamily
BtBc_RS13685	COG0346	lactoylglutathione lyase activity
BtBc_RS13700	COG1522	sequence-specific DNA binding
BtBc_RS13705	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS13710	COG1309	transcriptional regulator
BtBc_RS13715	COG2814	Major facilitator Superfamily
BtBc_RS13720	COG0640	Transcriptional regulator
BtBc_RS13725	COG0346	lactoylglutathione lyase activity
BtBc_RS13730	COG0798	PFAM Bile acid sodium symporter
BtBc_RS13740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS13750	COG1575	Belongs to the MenA family. Type 1 subfamily
BtBc_RS13755	COG0456	acetyltransferase
BtBc_RS13765	COG5609	conserved protein (DUF2294)
BtBc_RS13770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BtBc_RS13780	COG0288	reversible hydration of carbon dioxide
BtBc_RS13785	COG0657	acetylesterase activity
BtBc_RS13810	COG0415	Belongs to the DNA photolyase family
BtBc_RS13855	COG0598	Magnesium transport protein CorA
BtBc_RS13885	COG1846	Transcriptional regulator
BtBc_RS13890	COG0583	DNA-binding transcription factor activity
BtBc_RS13910	COG1335	isochorismatase
BtBc_RS13915	COG2267	carboxylic ester hydrolase activity
BtBc_RS13920	COG0737	Belongs to the 5'-nucleotidase family
BtBc_RS13935	COG2207	Transcriptional regulator
BtBc_RS13960	COG5002	protein histidine kinase activity
BtBc_RS13965	COG1063	alcohol dehydrogenase
BtBc_RS13985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BtBc_RS13990	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS13995	COG1522	sequence-specific DNA binding
BtBc_RS14010	COG0574	Belongs to the PEP-utilizing enzyme family
BtBc_RS14010	COG3848	Pyruvate phosphate dikinase
BtBc_RS14025	COG2963	transposase activity
BtBc_RS14030	COG2801	Transposase and inactivated derivatives
BtBc_RS14040	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BtBc_RS14050	COG0454	-acetyltransferase
BtBc_RS14060	COG3314	Sporulation integral membrane protein YlbJ
BtBc_RS14075	COG1960	acyl-CoA dehydrogenase activity
BtBc_RS14085	COG0640	Transcriptional regulator
BtBc_RS14090	COG3142	Participates in the control of copper homeostasis
BtBc_RS14100	COG1414	Transcriptional regulator
BtBc_RS14105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BtBc_RS14110	COG1984	allophanate hydrolase subunit 2
BtBc_RS14145	COG0768	penicillin binding
BtBc_RS14185	COG0833	amino acid
BtBc_RS14195	COG0730	response to heat
BtBc_RS14235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BtBc_RS14240	COG0697	spore germination
BtBc_RS14255	COG0456	acetyltransferase
BtBc_RS14260	COG0037	tRNA processing
BtBc_RS14260	COG0590	tRNA wobble adenosine to inosine editing
BtBc_RS14285	COG4884	unkown
BtBc_RS14285	COG3831	ATPase activity
BtBc_RS14305	COG1846	Transcriptional regulator
BtBc_RS14310	COG0778	Nitroreductase
BtBc_RS14395	COG0714	Associated with various cellular activities
BtBc_RS14435	COG0753	catalase activity
BtBc_RS14440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BtBc_RS14465	COG0463	Glycosyl transferase, family 2
BtBc_RS14505	COG0714	Associated with various cellular activities
BtBc_RS14535	COG0346	lactoylglutathione lyase activity
BtBc_RS14540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS14560	COG3655	Transcriptional regulator
BtBc_RS14570	COG1785	Belongs to the alkaline phosphatase family
BtBc_RS14575	COG2720	vancomycin resistance protein
BtBc_RS14585	COG3239	Fatty acid desaturase
BtBc_RS14595	COG0833	amino acid
BtBc_RS14600	COG1414	Transcriptional regulator
BtBc_RS14605	COG4187	Peptidase family M20/M25/M40
BtBc_RS14610	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BtBc_RS14625	COG2801	Transposase and inactivated derivatives
BtBc_RS14635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BtBc_RS14650	COG2329	Antibiotic biosynthesis monooxygenase
BtBc_RS14675	COG1070	Carbohydrate kinase
BtBc_RS14680	COG2390	Transcriptional regulator
BtBc_RS14690	COG1172	Belongs to the binding-protein-dependent transport system permease family
BtBc_RS14700	COG1879	ABC-type sugar transport system periplasmic component
BtBc_RS14715	COG0277	FAD linked oxidase domain protein
BtBc_RS14725	COG1388	LysM domain
BtBc_RS14725	COG3584	3D domain protein
BtBc_RS14765	COG1605	Chorismate mutase
BtBc_RS14765	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BtBc_RS14780	COG0287	Prephenate dehydrogenase
BtBc_RS14795	COG1309	transcriptional regulator
BtBc_RS14800	COG2409	Drug exporters of the RND superfamily
BtBc_RS14800	COG1033	growth of symbiont in host cell
BtBc_RS14810	COG2409	Drug exporters of the RND superfamily
BtBc_RS14810	COG1033	growth of symbiont in host cell
BtBc_RS14815	COG0488	(ABC) transporter
BtBc_RS14820	COG1368	sulfuric ester hydrolase activity
BtBc_RS14825	COG0861	Integral membrane protein TerC family
BtBc_RS14835	COG0346	lactoylglutathione lyase activity
BtBc_RS14840	COG4912	Dna alkylation repair
BtBc_RS14860	COG0697	spore germination
BtBc_RS14880	COG2746	aminoglycoside 3-N-acetyltransferase activity
BtBc_RS14910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BtBc_RS14915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BtBc_RS14920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BtBc_RS14930	COG0628	permease
BtBc_RS14980	COG1131	(ABC) transporter
BtBc_RS14995	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BtBc_RS15005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BtBc_RS15010	COG0436	Aminotransferase
BtBc_RS15045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BtBc_RS15060	COG2261	transglycosylase associated protein
BtBc_RS15080	COG0477	Major facilitator Superfamily
BtBc_RS15080	COG2814	Major facilitator Superfamily
BtBc_RS15085	COG4533	DNA binding
BtBc_RS15090	COG0789	Transcriptional regulator
BtBc_RS15095	COG1664	Polymer-forming cytoskeletal
BtBc_RS15105	COG2814	Major facilitator Superfamily
BtBc_RS15145	COG1307	EDD domain protein, DegV family
BtBc_RS15150	COG1164	Oligoendopeptidase f
BtBc_RS15160	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BtBc_RS15180	COG0745	RESPONSE REGULATOR receiver
BtBc_RS15185	COG3850	Histidine kinase
BtBc_RS15185	COG5002	protein histidine kinase activity
BtBc_RS15230	COG0667	Aldo Keto reductase
BtBc_RS15245	COG4948	Mandelate Racemase Muconate Lactonizing
BtBc_RS15255	COG4166	transmembrane transport
BtBc_RS15265	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BtBc_RS15275	COG0586	Pfam SNARE associated Golgi protein
BtBc_RS15315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BtBc_RS15320	COG3938	Belongs to the proline racemase family
BtBc_RS15330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BtBc_RS15335	COG1012	belongs to the aldehyde dehydrogenase family
BtBc_RS15340	COG1115	amino acid carrier protein
BtBc_RS15345	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BtBc_RS15350	COG1162	GTPase activity
BtBc_RS15365	COG3397	chitin binding
BtBc_RS15380	COG4637	Psort location Cytoplasmic, score
BtBc_RS15400	COG2801	Transposase and inactivated derivatives
BtBc_RS15420	COG2801	Transposase and inactivated derivatives
BtBc_RS15435	COG0514	ATP-dependent DNA helicase (RecQ)
BtBc_RS15440	COG2105	PFAM AIG2 family protein
BtBc_RS15450	COG3973	AAA domain
BtBc_RS15455	COG0456	acetyltransferase
BtBc_RS15500	COG2315	Protein conserved in bacteria
BtBc_RS15505	COG2226	methyltransferase
BtBc_RS15510	COG2205	protein histidine kinase activity
BtBc_RS15530	COG1819	glycosyl
BtBc_RS15535	COG3397	chitin binding
BtBc_RS15540	COG2153	protein acetylation
BtBc_RS15570	COG4175	Glycine betaine
BtBc_RS15570	COG0517	IMP dehydrogenase activity
BtBc_RS15575	COG4176	ABC-type proline glycine betaine transport system permease component
BtBc_RS15610	COG0456	acetyltransferase
BtBc_RS15610	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BtBc_RS15615	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS15630	COG3344	reverse transcriptase
BtBc_RS15650	COG2814	Major facilitator Superfamily
BtBc_RS15660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BtBc_RS15665	COG0022	dehydrogenase e1 component
BtBc_RS15670	COG0508	dehydrogenase complex catalyzes the overall conversion of
BtBc_RS15675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BtBc_RS15685	COG1959	2 iron, 2 sulfur cluster binding
BtBc_RS15715	COG3284	Transcriptional regulator
BtBc_RS15745	COG1309	transcriptional regulator
BtBc_RS15785	COG2959	enzyme of heme biosynthesis
BtBc_RS15800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS15835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BtBc_RS15840	COG0697	spore germination
BtBc_RS15845	COG0201	protein transport
BtBc_RS15860	COG0737	Belongs to the 5'-nucleotidase family
BtBc_RS15865	COG3227	Zinc metalloprotease (Elastase)
BtBc_RS15870	COG1523	belongs to the glycosyl hydrolase 13 family
BtBc_RS15900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BtBc_RS15915	COG0076	glutamate decarboxylase activity
BtBc_RS15920	COG0657	acetylesterase activity
BtBc_RS15925	COG1073	alpha beta
BtBc_RS15930	COG0577	efflux transmembrane transporter activity
BtBc_RS15935	COG1136	(ABC) transporter
BtBc_RS15950	COG5002	protein histidine kinase activity
BtBc_RS15955	COG0745	RESPONSE REGULATOR receiver
BtBc_RS15960	COG1011	Hydrolase
BtBc_RS15985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BtBc_RS16005	COG0322	excinuclease ABC activity
BtBc_RS16045	COG4667	esterase of the alpha-beta hydrolase superfamily
BtBc_RS16070	COG3878	Protein conserved in bacteria
BtBc_RS16095	COG0592	DNA-directed DNA polymerase activity
BtBc_RS16110	COG2223	nitrite transmembrane transporter activity
BtBc_RS16120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BtBc_RS16155	COG0697	spore germination
BtBc_RS16160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BtBc_RS16175	COG0584	glycerophosphoryl diester phosphodiesterase
BtBc_RS16195	COG2814	Major facilitator Superfamily
BtBc_RS16200	COG2814	Major facilitator Superfamily
BtBc_RS16245	COG0768	penicillin binding
BtBc_RS16250	COG0671	phosphoesterase, PA-phosphatase related
BtBc_RS16255	COG0604	alcohol dehydrogenase
BtBc_RS16260	COG5002	protein histidine kinase activity
BtBc_RS16265	COG0745	RESPONSE REGULATOR receiver
BtBc_RS16275	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BtBc_RS16290	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BtBc_RS16325	COG2205	protein histidine kinase activity
BtBc_RS16345	COG1794	racemase activity, acting on amino acids and derivatives
BtBc_RS16350	COG1819	glycosyl
BtBc_RS16360	COG0768	penicillin binding
BtBc_RS16365	COG5002	protein histidine kinase activity
BtBc_RS16370	COG0561	phosphatase activity
BtBc_RS16405	COG2124	cytochrome p450
BtBc_RS16430	COG3547	Transposase (IS116 IS110 IS902 family)
BtBc_RS16465	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BtBc_RS16475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BtBc_RS16480	COG0460	homoserine dehydrogenase
BtBc_RS16500	COG0577	efflux transmembrane transporter activity
BtBc_RS16505	COG1136	(ABC) transporter
BtBc_RS16515	COG0488	(ABC) transporter
BtBc_RS16520	COG2205	protein histidine kinase activity
BtBc_RS16525	COG3344	reverse transcriptase
BtBc_RS16535	COG0745	RESPONSE REGULATOR receiver
BtBc_RS16545	COG3773	Cell wall hydrolase
BtBc_RS16550	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BtBc_RS16555	COG3386	PFAM SMP-30 Gluconolaconase
BtBc_RS16565	COG0693	protein deglycase activity
BtBc_RS16570	COG2323	membrane
BtBc_RS16590	COG3344	reverse transcriptase
BtBc_RS16615	COG2368	4-hydroxyphenylacetate
BtBc_RS16620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BtBc_RS16650	COG1131	(ABC) transporter
BtBc_RS16660	COG0583	DNA-binding transcription factor activity
BtBc_RS16665	COG1942	4-Oxalocrotonate Tautomerase
BtBc_RS16720	COG2207	Transcriptional regulator
BtBc_RS16725	COG3227	Zinc metalloprotease (Elastase)
BtBc_RS16740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BtBc_RS16770	COG1686	Belongs to the peptidase S11 family
BtBc_RS16780	COG0572	uridine kinase
BtBc_RS16795	COG3547	Transposase (IS116 IS110 IS902 family)
BtBc_RS16820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BtBc_RS16825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BtBc_RS16830	COG1024	Enoyl-CoA hydratase
BtBc_RS16835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BtBc_RS16840	COG0511	ligase activity, forming carbon-carbon bonds
BtBc_RS16845	COG0439	Biotin carboxylase
BtBc_RS16850	COG1960	acyl-CoA dehydrogenase activity
BtBc_RS16865	COG1309	transcriptional regulator
BtBc_RS16875	COG1131	(ABC) transporter
BtBc_RS16885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BtBc_RS16900	COG0768	penicillin binding
BtBc_RS16905	COG0768	penicillin binding
BtBc_RS16915	COG1595	DNA-templated transcription, initiation
BtBc_RS16920	COG0768	penicillin binding
BtBc_RS16930	COG2239	Acts as a magnesium transporter
BtBc_RS16935	COG0772	Belongs to the SEDS family
BtBc_RS16960	COG0076	glutamate decarboxylase activity
BtBc_RS16970	COG1533	DNA photolyase activity
BtBc_RS16995	COG0814	amino acid
BtBc_RS17000	COG1760	l-serine dehydratase
BtBc_RS17005	COG1760	l-serine dehydratase
BtBc_RS17035	COG0367	asparagine synthase
BtBc_RS17040	COG1309	transcriptional regulator
BtBc_RS17060	COG1396	sequence-specific DNA binding
BtBc_RS17160	COG5444	nuclease activity
BtBc_RS17185	COG1876	peptidase activity
BtBc_RS17190	COG2843	Capsule synthesis protein
BtBc_RS17200	COG0477	Major facilitator Superfamily
BtBc_RS17215	COG1846	Transcriptional regulator
BtBc_RS17220	COG2814	Major facilitator Superfamily
BtBc_RS17235	COG2031	fatty acid transporter
BtBc_RS17245	COG2249	NAD(P)H dehydrogenase (quinone) activity
BtBc_RS17300	COG1288	antiporter activity
BtBc_RS17315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BtBc_RS17325	COG1733	regulation of RNA biosynthetic process
BtBc_RS17330	COG0778	Nitroreductase
BtBc_RS17340	COG0469	pyruvate kinase activity
BtBc_RS17360	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS17370	COG1131	(ABC) transporter
BtBc_RS17395	COG1011	Hydrolase
BtBc_RS17405	COG2365	Tyrosine phosphatase family
BtBc_RS17440	COG0628	permease
BtBc_RS17465	COG0500	methyltransferase
BtBc_RS17475	COG0477	Major facilitator Superfamily
BtBc_RS17505	COG1253	flavin adenine dinucleotide binding
BtBc_RS17510	COG0789	Transcriptional regulator
BtBc_RS17520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BtBc_RS17550	COG0697	spore germination
BtBc_RS17560	COG1357	PFAM Pentapeptide repeats (8 copies)
BtBc_RS17565	COG3813	Protein conserved in bacteria
BtBc_RS17570	COG2706	6-phosphogluconolactonase activity
BtBc_RS17575	COG1070	Carbohydrate kinase
BtBc_RS17585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BtBc_RS17590	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BtBc_RS17595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BtBc_RS17600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BtBc_RS17625	COG0840	transmembrane signaling receptor activity
BtBc_RS17635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BtBc_RS17635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BtBc_RS17640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BtBc_RS17640	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BtBc_RS17645	COG1733	regulation of RNA biosynthetic process
BtBc_RS17660	COG0814	amino acid
BtBc_RS17685	COG2188	Transcriptional regulator
BtBc_RS17690	COG0673	inositol 2-dehydrogenase activity
BtBc_RS17710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BtBc_RS17730	COG0384	phenazine biosynthesis protein PhzF
BtBc_RS17750	COG0318	PFAM AMP-dependent synthetase and ligase
BtBc_RS17755	COG2249	NAD(P)H dehydrogenase (quinone) activity
BtBc_RS17760	COG1733	regulation of RNA biosynthetic process
BtBc_RS17780	COG1191	sigma factor activity
BtBc_RS17835	COG1151	hydroxylamine reductase activity
BtBc_RS17890	COG1113	amino acid transport
BtBc_RS17895	COG2814	Major facilitator Superfamily
BtBc_RS17925	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BtBc_RS17930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BtBc_RS17940	COG1247	-acetyltransferase
BtBc_RS17945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BtBc_RS17950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BtBc_RS17955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BtBc_RS17960	COG3739	integral membrane protein
BtBc_RS17980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS17995	COG0583	DNA-binding transcription factor activity
BtBc_RS18005	COG2890	protein-(glutamine-N5) methyltransferase activity
BtBc_RS18020	COG1193	negative regulation of DNA recombination
BtBc_RS18030	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BtBc_RS18035	COG1164	Oligoendopeptidase f
BtBc_RS18065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BtBc_RS18090	COG0584	glycerophosphoryl diester phosphodiesterase
BtBc_RS18100	COG0640	Transcriptional regulator
BtBc_RS18105	COG0604	alcohol dehydrogenase
BtBc_RS18115	COG0457	Tetratricopeptide repeat
BtBc_RS18125	COG0385	Bile acid
BtBc_RS18130	COG0277	FAD linked oxidase domain protein
BtBc_RS18155	COG1183	phosphatidylcholine synthase activity
BtBc_RS18165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BtBc_RS18165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BtBc_RS18170	COG1252	NADH dehydrogenase
BtBc_RS18180	COG0823	Involved in the tonB-independent uptake of proteins
BtBc_RS18185	COG3397	chitin binding
BtBc_RS18195	COG0697	spore germination
BtBc_RS18225	COG3344	reverse transcriptase
BtBc_RS18250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BtBc_RS18260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BtBc_RS18270	COG0457	Tetratricopeptide repeat
BtBc_RS18305	COG1404	Belongs to the peptidase S8 family
BtBc_RS18345	COG0488	(ABC) transporter
BtBc_RS18365	COG3852	Histidine kinase
BtBc_RS18375	COG1285	pathogenesis
BtBc_RS18385	COG2514	catechol 2,3-dioxygenase activity
BtBc_RS18390	COG2720	vancomycin resistance protein
BtBc_RS18425	COG0716	FMN binding
BtBc_RS18460	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS18470	COG0165	Argininosuccinate lyase
BtBc_RS18485	COG4145	pantothenate transmembrane transporter activity
BtBc_RS18495	COG1012	belongs to the aldehyde dehydrogenase family
BtBc_RS18500	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS18510	COG1657	PFAM Prenyltransferase squalene oxidase
BtBc_RS18515	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BtBc_RS18520	COG2962	Rard protein
BtBc_RS18525	COG3326	Membrane
BtBc_RS18540	COG0489	protein tyrosine kinase activity
BtBc_RS18550	COG0314	molybdopterin synthase activity
BtBc_RS18555	COG0303	'Molybdopterin
BtBc_RS18560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BtBc_RS18565	COG2116	formate transmembrane transporter activity
BtBc_RS18575	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BtBc_RS18580	COG5609	conserved protein (DUF2294)
BtBc_RS18585	COG2427	Protein of unknown function (DUF1641)
BtBc_RS18590	COG3383	formate dehydrogenase (NAD+) activity
BtBc_RS18595	COG0697	spore germination
BtBc_RS18610	COG0531	amino acid
BtBc_RS18645	COG2226	methyltransferase
BtBc_RS18650	COG4166	transmembrane transport
BtBc_RS18655	COG4166	transmembrane transport
BtBc_RS18660	COG4166	transmembrane transport
BtBc_RS18665	COG1316	TRANSCRIPTIONal
BtBc_RS18675	COG1595	DNA-templated transcription, initiation
BtBc_RS18685	COG1131	(ABC) transporter
BtBc_RS18705	COG0673	inositol 2-dehydrogenase activity
BtBc_RS18710	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BtBc_RS18715	COG0187	DNA topoisomerase II activity
BtBc_RS18720	COG1832	CoA-binding protein
BtBc_RS18725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BtBc_RS18730	COG0745	RESPONSE REGULATOR receiver
BtBc_RS18740	COG1328	CTP reductase activity
BtBc_RS18740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BtBc_RS18750	COG4841	protein insertion into membrane
BtBc_RS18755	COG0824	Thioesterase
BtBc_RS18790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BtBc_RS18800	COG1132	(ABC) transporter
BtBc_RS18805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BtBc_RS18835	COG2211	Major facilitator Superfamily
BtBc_RS18845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BtBc_RS18860	COG0183	Belongs to the thiolase family
BtBc_RS18865	COG0318	PFAM AMP-dependent synthetase and ligase
BtBc_RS18870	COG1268	BioY protein
BtBc_RS18875	COG0318	PFAM AMP-dependent synthetase and ligase
BtBc_RS18880	COG1396	sequence-specific DNA binding
BtBc_RS18905	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BtBc_RS18925	COG0830	nickel cation binding
BtBc_RS18965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BtBc_RS18975	COG5002	protein histidine kinase activity
BtBc_RS18980	COG0400	carboxylic ester hydrolase activity
BtBc_RS18985	COG0346	lactoylglutathione lyase activity
BtBc_RS19000	COG0069	glutamate synthase activity
BtBc_RS19005	COG1902	pentaerythritol trinitrate reductase activity
BtBc_RS19010	COG3344	reverse transcriptase
BtBc_RS19020	COG1329	Transcriptional regulator
BtBc_RS19025	COG0010	Belongs to the arginase family
BtBc_RS19050	COG2226	methyltransferase
BtBc_RS19075	COG4846	Membrane protein involved in cytochrome C biogenesis
BtBc_RS19080	COG0785	Cytochrome C biogenesis protein
BtBc_RS19090	COG1473	amidohydrolase
BtBc_RS19095	COG2963	transposase activity
BtBc_RS19100	COG2801	Transposase and inactivated derivatives
BtBc_RS19125	COG0583	DNA-binding transcription factor activity
BtBc_RS19135	COG1346	cytolysis
BtBc_RS19150	COG0730	response to heat
BtBc_RS19175	COG1132	(ABC) transporter
BtBc_RS19180	COG1132	(ABC) transporter
BtBc_RS19215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BtBc_RS19220	COG0737	Belongs to the 5'-nucleotidase family
BtBc_RS19230	COG0737	Belongs to the 5'-nucleotidase family
BtBc_RS19240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BtBc_RS19260	COG1695	Transcriptional regulator
BtBc_RS19265	COG0174	glutamine synthetase
BtBc_RS19270	COG0789	Transcriptional regulator
BtBc_RS19275	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BtBc_RS19280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BtBc_RS19285	COG2860	membrane
BtBc_RS19295	COG0464	growth
BtBc_RS19325	COG1388	LysM domain
BtBc_RS19325	COG3584	3D domain protein
BtBc_RS19330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BtBc_RS19330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BtBc_RS19330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BtBc_RS19335	COG1105	Belongs to the carbohydrate kinase PfkB family
BtBc_RS19340	COG1349	DNA-binding transcription factor activity
BtBc_RS19345	COG1979	alcohol dehydrogenase
BtBc_RS19350	COG2322	membrane
BtBc_RS19365	COG1113	amino acid transport
BtBc_RS19375	COG1408	metallophosphoesterase
BtBc_RS19380	COG2116	formate transmembrane transporter activity
BtBc_RS19395	COG2217	Heavy metal translocating P-type atpase
BtBc_RS19400	COG2608	mercury ion transmembrane transporter activity
BtBc_RS19405	COG1937	Protein conserved in bacteria
BtBc_RS19415	COG2819	hydrolase of the alpha beta superfamily
BtBc_RS19420	COG1120	ATPase activity
BtBc_RS19425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BtBc_RS19430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BtBc_RS19435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BtBc_RS19440	COG2169	Transcriptional regulator
BtBc_RS19445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BtBc_RS19450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BtBc_RS19470	COG2267	carboxylic ester hydrolase activity
BtBc_RS19475	COG3300	MHYT domain
BtBc_RS19475	COG5001	Diguanylate cyclase
BtBc_RS19495	COG1086	Polysaccharide biosynthesis protein
BtBc_RS19510	COG1346	cytolysis
BtBc_RS19520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BtBc_RS19530	COG2188	Transcriptional regulator
BtBc_RS19535	COG2723	6-phospho-beta-galactosidase activity
BtBc_RS19540	COG0823	Involved in the tonB-independent uptake of proteins
BtBc_RS19545	COG1404	Belongs to the peptidase S8 family
BtBc_RS19550	COG3773	Cell wall hydrolase
BtBc_RS19560	COG1368	sulfuric ester hydrolase activity
BtBc_RS19565	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BtBc_RS19590	COG4550	Control of competence regulator ComK, YlbF/YmcA
BtBc_RS19600	COG1013	pyruvate-flavodoxin oxidoreductase activity
BtBc_RS19605	COG0674	pyruvate-flavodoxin oxidoreductase activity
BtBc_RS19605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BtBc_RS19615	COG2359	stage V sporulation protein S
BtBc_RS19620	COG1692	metallophosphoesterase
BtBc_RS19640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BtBc_RS19645	COG1426	Protein conserved in bacteria
BtBc_RS19660	COG0300	oxidoreductase activity
BtBc_RS19665	COG0612	Peptidase, M16
BtBc_RS19670	COG0612	Peptidase, M16
BtBc_RS19675	COG1079	Belongs to the binding-protein-dependent transport system permease family
BtBc_RS19680	COG4603	Belongs to the binding-protein-dependent transport system permease family
BtBc_RS19685	COG3845	ABC transporter
BtBc_RS19690	COG1744	ABC transporter substrate-binding protein PnrA-like
BtBc_RS19695	COG2188	Transcriptional regulator
BtBc_RS19710	COG0740	serine-type endopeptidase activity
BtBc_RS19715	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BtBc_RS19725	COG0527	aspartate kinase activity
BtBc_RS19730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BtBc_RS19735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BtBc_RS19740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BtBc_RS19745	COG1873	PFAM PRC-barrel domain
BtBc_RS19750	COG0612	Peptidase, M16
BtBc_RS19755	COG0726	polysaccharide deacetylase
BtBc_RS19770	COG0196	riboflavin kinase activity
BtBc_RS19780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BtBc_RS19785	COG1550	Protein conserved in bacteria
BtBc_RS19795	COG1358	cellular component organization or biogenesis
BtBc_RS19800	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BtBc_RS19805	COG0195	Participates in both transcription termination and antitermination
BtBc_RS19825	COG0750	zinc metalloprotease
BtBc_RS19835	COG4589	Belongs to the CDS family
BtBc_RS19880	COG4974	Belongs to the 'phage' integrase family
BtBc_RS19890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BtBc_RS19895	COG0758	DNA mediated transformation
BtBc_RS19900	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BtBc_RS19940	COG1837	Belongs to the UPF0109 family
BtBc_RS19950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BtBc_RS19960	COG0552	protein localization to endoplasmic reticulum
BtBc_RS19965	COG1196	nuclear chromosome segregation
BtBc_RS19970	COG3344	reverse transcriptase
BtBc_RS19975	COG1196	nuclear chromosome segregation
BtBc_RS19985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BtBc_RS19990	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS19995	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BtBc_RS20010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BtBc_RS20015	COG1461	Dihydroxyacetone kinase
BtBc_RS20020	COG1302	Protein conserved in bacteria
BtBc_RS20035	COG1564	THIamine pyrophosphokinase
BtBc_RS20040	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BtBc_RS20050	COG2815	serine threonine protein kinase
BtBc_RS20050	COG0515	serine threonine protein kinase
BtBc_RS20055	COG0631	protein serine/threonine phosphatase activity
BtBc_RS20065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BtBc_RS20065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BtBc_RS20080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BtBc_RS20085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BtBc_RS20105	COG1561	YicC-like family, N-terminal region
BtBc_RS20110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BtBc_RS20120	COG0006	proline dipeptidase activity
BtBc_RS20135	COG3069	C4-dicarboxylate transmembrane transporter activity
BtBc_RS20195	COG0564	pseudouridine synthase activity
BtBc_RS20215	COG3599	regulation of cell shape
BtBc_RS20220	COG2302	S4 RNA-binding domain
BtBc_RS20225	COG0762	integral membrane protein
BtBc_RS20235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BtBc_RS20245	COG1873	PFAM PRC-barrel domain
BtBc_RS20250	COG1191	sigma factor activity
BtBc_RS20255	COG1191	sigma factor activity
BtBc_RS20265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BtBc_RS20270	COG0849	cell division
BtBc_RS20290	COG0772	Belongs to the SEDS family
BtBc_RS20310	COG0768	penicillin binding
BtBc_RS20315	COG0768	penicillin binding
BtBc_RS20335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BtBc_RS20350	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BtBc_RS20355	COG1399	metal-binding, possibly nucleic acid-binding protein
BtBc_RS20365	COG3480	Lon protease (S16) C-terminal proteolytic domain
BtBc_RS20370	COG1752	Esterase of the alpha-beta hydrolase superfamily
BtBc_RS20375	COG3314	Sporulation integral membrane protein YlbJ
BtBc_RS20385	COG0742	ribosomal rna small subunit methyltransferase
BtBc_RS20400	COG3679	Belongs to the UPF0342 family
BtBc_RS20405	COG0406	alpha-ribazole phosphatase activity
BtBc_RS20420	COG2340	Cysteine-rich secretory protein family
BtBc_RS20435	COG3336	cytochrome c oxidase
BtBc_RS20470	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BtBc_RS20475	COG0772	Belongs to the SEDS family
BtBc_RS20485	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BtBc_RS20490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BtBc_RS20500	COG4896	Protein conserved in bacteria
BtBc_RS20515	COG1217	gtp-binding protein TYPA
BtBc_RS20525	COG0483	inositol monophosphate 1-phosphatase activity
BtBc_RS20545	COG1982	Orn Lys Arg decarboxylase major
BtBc_RS20590	COG0022	dehydrogenase e1 component
BtBc_RS20595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BtBc_RS20610	COG0561	phosphatase activity
BtBc_RS20620	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BtBc_RS20625	COG0569	domain protein
BtBc_RS20645	COG0583	DNA-binding transcription factor activity
BtBc_RS20650	COG0517	IMP dehydrogenase activity
BtBc_RS20660	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BtBc_RS20670	COG4703	Protein of unknown function (DUF1797)
BtBc_RS20685	COG2200	EAL domain
BtBc_RS20690	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS20695	COG1408	metallophosphoesterase
BtBc_RS20740	COG2814	Major facilitator Superfamily
BtBc_RS20760	COG3209	COG3209 Rhs family protein
BtBc_RS20770	COG2205	protein histidine kinase activity
BtBc_RS20780	COG0436	Aminotransferase
BtBc_RS20785	COG1609	Transcriptional regulator
BtBc_RS20790	COG3833	ABC-type maltose transport systems, permease component
BtBc_RS20795	COG1175	transmembrane transport
BtBc_RS20800	COG2182	Extracellular solute-binding protein
BtBc_RS20810	COG0366	Alpha amylase catalytic
BtBc_RS20815	COG3842	ATPase activity
BtBc_RS20850	COG0183	Belongs to the thiolase family
BtBc_RS20880	COG1695	Transcriptional regulator
BtBc_RS20885	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS20905	COG4974	Belongs to the 'phage' integrase family
BtBc_RS20930	COG1012	belongs to the aldehyde dehydrogenase family
BtBc_RS20935	COG0640	Transcriptional regulator
BtBc_RS20965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BtBc_RS20970	COG0436	Aminotransferase
BtBc_RS21005	COG2084	Dehydrogenase
BtBc_RS21015	COG2199	diguanylate cyclase activity
BtBc_RS21020	COG0778	Nitroreductase
BtBc_RS21045	COG1263	PTS System
BtBc_RS21045	COG2190	(PTS) system
BtBc_RS21045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BtBc_RS21050	COG3711	transcriptional antiterminator
BtBc_RS21060	COG2188	Transcriptional regulator
BtBc_RS21070	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BtBc_RS21095	COG1547	Domain of unknown function (DUF309)
BtBc_RS21100	COG0456	acetyltransferase
BtBc_RS21105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BtBc_RS21110	COG4086	secreted protein
BtBc_RS21115	COG0561	phosphatase activity
BtBc_RS21120	COG0697	spore germination
BtBc_RS21135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BtBc_RS21180	COG1686	Belongs to the peptidase S11 family
BtBc_RS21185	COG1725	Transcriptional regulator
BtBc_RS21190	COG1131	(ABC) transporter
BtBc_RS21205	COG1846	Transcriptional regulator
BtBc_RS21220	COG0598	Magnesium transport protein CorA
BtBc_RS21245	COG4974	Belongs to the 'phage' integrase family
BtBc_RS21255	COG0735	belongs to the Fur family
BtBc_RS21260	COG1300	Membrane
BtBc_RS21280	COG0667	Aldo Keto reductase
BtBc_RS21285	COG0656	L-ascorbic acid biosynthetic process
BtBc_RS21290	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BtBc_RS21290	COG0456	acetyltransferase
BtBc_RS21300	COG0737	Belongs to the 5'-nucleotidase family
BtBc_RS21300	COG4085	toxin activity
BtBc_RS21300	COG1525	nuclease
BtBc_RS21310	COG0596	Alpha beta hydrolase
BtBc_RS21315	COG2056	Na+-H+ antiporter family
BtBc_RS21320	COG1609	Transcriptional regulator
BtBc_RS21325	COG0456	acetyltransferase
BtBc_RS21330	COG1073	alpha beta
BtBc_RS21345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BtBc_RS21345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BtBc_RS21350	COG0307	riboflavin synthase, alpha
BtBc_RS21380	COG1073	alpha beta
BtBc_RS21380	COG2226	methyltransferase
BtBc_RS21395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BtBc_RS21405	COG1757	Na H antiporter
BtBc_RS21410	COG0737	Belongs to the 5'-nucleotidase family
BtBc_RS21420	COG1522	sequence-specific DNA binding
BtBc_RS21465	COG0300	oxidoreductase activity
BtBc_RS21470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BtBc_RS21475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BtBc_RS21480	COG1760	l-serine dehydratase
BtBc_RS21485	COG1760	l-serine dehydratase
BtBc_RS21515	COG1285	pathogenesis
BtBc_RS21525	COG2195	Cleaves the N-terminal amino acid of tripeptides
BtBc_RS21530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS21540	COG1376	ErfK ybiS ycfS ynhG family protein
BtBc_RS21545	COG4129	membrane
BtBc_RS21550	COG1126	abc transporter atp-binding protein
BtBc_RS21555	COG0765	amino acid transport
BtBc_RS21560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BtBc_RS21580	COG2323	membrane
BtBc_RS21585	COG0772	Belongs to the SEDS family
BtBc_RS21590	COG0508	dehydrogenase complex catalyzes the overall conversion of
BtBc_RS21595	COG0022	dehydrogenase e1 component
BtBc_RS21600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BtBc_RS21605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BtBc_RS21620	COG0280	phosphate acetyltransferase
BtBc_RS21625	COG3290	protein histidine kinase activity
BtBc_RS21625	COG3829	transcription factor binding
BtBc_RS21635	COG0584	glycerophosphoryl diester phosphodiesterase
BtBc_RS21640	COG3093	addiction module antidote protein HigA
BtBc_RS21655	COG0750	zinc metalloprotease
BtBc_RS21660	COG0497	DNA recombination
BtBc_RS21670	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BtBc_RS21680	COG0142	geranyltranstransferase activity
BtBc_RS21705	COG1302	Protein conserved in bacteria
BtBc_RS21710	COG0439	Biotin carboxylase
BtBc_RS21715	COG0511	ligase activity, forming carbon-carbon bonds
BtBc_RS21755	COG3854	ATPases associated with a variety of cellular activities
BtBc_RS21780	COG0006	proline dipeptidase activity
BtBc_RS21795	COG3872	metal-dependent enzyme
BtBc_RS21805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BtBc_RS21840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BtBc_RS21850	COG1609	Transcriptional regulator
BtBc_RS21860	COG2076	Multidrug Resistance protein
BtBc_RS21865	COG2076	Multidrug Resistance protein
BtBc_RS21895	COG1131	(ABC) transporter
BtBc_RS21900	COG1725	Transcriptional regulator
BtBc_RS21930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BtBc_RS21995	COG1459	type II secretion system
BtBc_RS22000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BtBc_RS22055	COG0646	methionine synthase
BtBc_RS22055	COG1410	methionine synthase
BtBc_RS22060	COG0646	methionine synthase
BtBc_RS22060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BtBc_RS22065	COG0626	cystathionine gamma-synthase activity
BtBc_RS22070	COG0626	cystathionine gamma-synthase activity
BtBc_RS22090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BtBc_RS22095	COG1940	carbohydrate kinase activity
BtBc_RS22100	COG4483	Protein conserved in bacteria
BtBc_RS22105	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BtBc_RS22110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BtBc_RS22115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BtBc_RS22120	COG0704	Plays a role in the regulation of phosphate uptake
BtBc_RS22130	COG0573	inorganic phosphate transmembrane transporter activity
BtBc_RS22135	COG0573	inorganic phosphate transmembrane transporter activity
BtBc_RS22140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BtBc_RS22145	COG0768	penicillin binding
BtBc_RS22150	COG0477	Major facilitator Superfamily
BtBc_RS22155	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BtBc_RS22165	COG5521	maltodextrose utilization protein MalA
BtBc_RS22180	COG0735	belongs to the Fur family
BtBc_RS22185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BtBc_RS22190	COG1121	(ABC) transporter
BtBc_RS22195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BtBc_RS22225	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BtBc_RS22230	COG2384	SAM-dependent methyltransferase
BtBc_RS22240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BtBc_RS22245	COG0358	DNA primase activity
BtBc_RS22255	COG0517	IMP dehydrogenase activity
BtBc_RS22270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BtBc_RS22275	COG0295	cytidine deaminase activity
BtBc_RS22280	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BtBc_RS22290	COG1480	7TM receptor with intracellular HD hydrolase
BtBc_RS22295	COG1702	phosphate starvation-inducible protein PhoH
BtBc_RS22310	COG1610	YqeY-like protein
BtBc_RS22315	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BtBc_RS22320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BtBc_RS22325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BtBc_RS22355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BtBc_RS22360	COG1733	regulation of RNA biosynthetic process
BtBc_RS22385	COG1466	dna polymerase III delta subunit
BtBc_RS22395	COG2333	competence protein COMEC
BtBc_RS22395	COG0658	competence protein
BtBc_RS22400	COG2131	deaminase
BtBc_RS22405	COG1596	polysaccharide export
BtBc_RS22405	COG1555	photosystem II stabilization
BtBc_RS22410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BtBc_RS22415	COG2226	methyltransferase
BtBc_RS22420	COG0799	negative regulation of ribosome biogenesis
BtBc_RS22425	COG1713	HD superfamily hydrolase involved in NAD metabolism
BtBc_RS22435	COG1534	Rna-binding protein
BtBc_RS22445	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BtBc_RS22450	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BtBc_RS22475	COG1595	DNA-templated transcription, initiation
BtBc_RS22485	COG0778	Nitroreductase
BtBc_RS22490	COG2357	RelA SpoT domain protein
BtBc_RS22500	COG1785	Belongs to the alkaline phosphatase family
BtBc_RS22510	COG2267	carboxylic ester hydrolase activity
BtBc_RS22560	COG3186	Phenylalanine-4-hydroxylase
BtBc_RS22570	COG2514	catechol 2,3-dioxygenase activity
BtBc_RS22575	COG2259	Doxx family
BtBc_RS22615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BtBc_RS22625	COG1454	alcohol dehydrogenase
BtBc_RS22625	COG1012	belongs to the aldehyde dehydrogenase family
BtBc_RS22630	COG0626	cystathionine gamma-synthase activity
BtBc_RS22635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BtBc_RS22660	COG0768	penicillin binding
BtBc_RS22680	COG0826	peptidase U32
BtBc_RS22685	COG0826	peptidase U32
BtBc_RS22690	COG4122	O-methyltransferase activity
BtBc_RS22695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BtBc_RS22725	COG0628	permease
BtBc_RS22745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BtBc_RS22760	COG1104	cysteine desulfurase activity
BtBc_RS22765	COG1959	2 iron, 2 sulfur cluster binding
BtBc_RS22770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BtBc_RS22785	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BtBc_RS22810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BtBc_RS22820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BtBc_RS22820	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BtBc_RS22825	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BtBc_RS22830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BtBc_RS22830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BtBc_RS22840	COG2244	polysaccharide biosynthetic process
BtBc_RS22845	COG2323	membrane
BtBc_RS22855	COG1862	Preprotein translocase
BtBc_RS22885	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BtBc_RS22915	COG0157	Belongs to the NadC ModD family
BtBc_RS22920	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BtBc_RS22925	COG1104	cysteine desulfurase activity
BtBc_RS22930	COG1827	regulation of RNA biosynthetic process
BtBc_RS22935	COG2258	MOSC domain
BtBc_RS22940	COG0077	Prephenate dehydratase
BtBc_RS22945	COG0577	efflux transmembrane transporter activity
BtBc_RS22950	COG0577	efflux transmembrane transporter activity
BtBc_RS22955	COG1136	(ABC) transporter
BtBc_RS22960	COG5002	protein histidine kinase activity
BtBc_RS22965	COG0745	RESPONSE REGULATOR receiver
BtBc_RS22975	COG3290	protein histidine kinase activity
BtBc_RS22985	COG2868	ribosomal protein
BtBc_RS22995	COG1530	ribonuclease E activity
BtBc_RS23000	COG1994	Peptidase M50
BtBc_RS23005	COG0739	heme binding
BtBc_RS23010	COG2894	cell division
BtBc_RS23030	COG1077	Cell shape determining protein MreB Mrl
BtBc_RS23050	COG0285	dihydrofolate synthase activity
BtBc_RS23065	COG1388	LysM domain
BtBc_RS23075	COG0113	porphobilinogen synthase activity
BtBc_RS23080	COG1587	Uroporphyrinogen-III synthase
BtBc_RS23090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BtBc_RS23100	COG1846	Transcriptional regulator
BtBc_RS23105	COG1764	response to oxidative stress
BtBc_RS23120	COG0470	DNA polymerase III
BtBc_RS23120	COG1067	ATP-dependent peptidase activity
BtBc_RS23160	COG0622	Phosphoesterase
BtBc_RS23175	COG5401	PFAM Sporulation and spore germination
BtBc_RS23195	COG2197	response regulator
BtBc_RS23200	COG2233	PERMEase
BtBc_RS23205	COG0402	S-adenosylhomocysteine deaminase activity
BtBc_RS23210	COG1983	PspC domain protein
BtBc_RS23215	COG1396	sequence-specific DNA binding
BtBc_RS23220	COG0697	spore germination
BtBc_RS23230	COG1959	2 iron, 2 sulfur cluster binding
BtBc_RS23235	COG1668	transmembrane transport
BtBc_RS23240	COG4152	abc transporter atp-binding protein
BtBc_RS23245	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BtBc_RS23250	COG1360	Flagellar Motor Protein
BtBc_RS23255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BtBc_RS23260	COG1876	peptidase activity
BtBc_RS23265	COG0824	Thioesterase
BtBc_RS23270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BtBc_RS23275	COG1053	succinate dehydrogenase
BtBc_RS23280	COG2009	succinate dehydrogenase
BtBc_RS23285	COG1719	4-vinyl reductase, 4VR
BtBc_RS23295	COG3118	belongs to the thioredoxin family
BtBc_RS23300	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BtBc_RS23305	COG2086	electron transfer activity
BtBc_RS23310	COG1024	Enoyl-CoA hydratase
BtBc_RS23315	COG1309	transcriptional regulator
BtBc_RS23320	COG0318	PFAM AMP-dependent synthetase and ligase
BtBc_RS23345	COG2318	DinB family
BtBc_RS23370	COG1131	(ABC) transporter
BtBc_RS23375	COG2205	protein histidine kinase activity
BtBc_RS23380	COG0745	RESPONSE REGULATOR receiver
BtBc_RS23390	COG4895	conserved protein (DUF2196)
BtBc_RS23395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BtBc_RS23405	COG4509	Sortase family
BtBc_RS23410	COG1120	ATPase activity
BtBc_RS23425	COG5386	Cell surface protein
BtBc_RS23435	COG5386	Cell surface protein
BtBc_RS23440	COG1114	Component of the transport system for branched-chain amino acids
BtBc_RS23445	COG1187	pseudouridine synthase activity
BtBc_RS23455	COG1796	DNA polymerase
BtBc_RS23455	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BtBc_RS23460	COG1286	toxin biosynthetic process
BtBc_RS23505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BtBc_RS23515	COG1418	mRNA catabolic process
BtBc_RS23535	COG2814	Major facilitator Superfamily
BtBc_RS23540	COG1566	PFAM secretion protein HlyD family protein
BtBc_RS23545	COG1309	transcriptional regulator
BtBc_RS23550	COG1363	Peptidase, m42
BtBc_RS23575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BtBc_RS23590	COG1484	DNA-dependent DNA replication
BtBc_RS23595	COG3611	Membrane attachment protein
BtBc_RS23605	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BtBc_RS23610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BtBc_RS23620	COG1971	Probably functions as a manganese efflux pump
BtBc_RS23630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BtBc_RS23630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BtBc_RS23635	COG5002	protein histidine kinase activity
BtBc_RS23640	COG0745	RESPONSE REGULATOR receiver
BtBc_RS23660	COG0538	isocitrate dehydrogenase activity
BtBc_RS23665	COG0372	Belongs to the citrate synthase family
BtBc_RS23675	COG0628	permease
BtBc_RS23680	COG3030	protein affecting phage T7 exclusion by the F plasmid
BtBc_RS23705	COG1725	Transcriptional regulator
BtBc_RS23710	COG0281	malic enzyme
BtBc_RS23715	COG0587	DNA-directed DNA polymerase activity
BtBc_RS23730	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BtBc_RS23745	COG4109	DRTGG domain
BtBc_RS23760	COG0006	proline dipeptidase activity
BtBc_RS23795	COG0662	Cupin 2, conserved barrel domain protein
BtBc_RS23810	COG1028	Short-chain dehydrogenase reductase Sdr
BtBc_RS23815	COG0589	response to stress
BtBc_RS23860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BtBc_RS23885	COG0827	DNA restriction-modification system
BtBc_RS23890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BtBc_RS23895	COG3874	Sporulation protein YtfJ
BtBc_RS23910	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BtBc_RS23920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BtBc_RS23935	COG1104	cysteine desulfurase activity
BtBc_RS23945	COG0583	DNA-binding transcription factor activity
BtBc_RS23950	COG0697	spore germination
BtBc_RS23955	COG1309	transcriptional regulator
BtBc_RS23960	COG1956	GAF domain-containing protein
BtBc_RS23965	COG0626	cystathionine gamma-synthase activity
BtBc_RS24005	COG1595	DNA-templated transcription, initiation
BtBc_RS24015	COG0110	maltose O-acetyltransferase activity
BtBc_RS24020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BtBc_RS24025	COG0454	-acetyltransferase
BtBc_RS24030	COG0517	IMP dehydrogenase activity
BtBc_RS24035	COG0123	including yeast histone deacetylase and acetoin utilization protein
BtBc_RS24050	COG0745	RESPONSE REGULATOR receiver
BtBc_RS24060	COG0666	response to abiotic stimulus
BtBc_RS24065	COG2972	Histidine kinase
BtBc_RS24065	COG0745	RESPONSE REGULATOR receiver
BtBc_RS24085	COG3279	Response regulator of the LytR AlgR family
BtBc_RS24120	COG1609	Transcriptional regulator
BtBc_RS24125	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BtBc_RS24125	COG1605	Chorismate mutase
BtBc_RS24130	COG4851	CamS sex pheromone cAM373 precursor
BtBc_RS24135	COG3118	belongs to the thioredoxin family
BtBc_RS24145	COG2309	aminopeptidase activity
BtBc_RS24160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS24175	COG1674	ftsk spoiiie
BtBc_RS24190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BtBc_RS24200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BtBc_RS24205	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BtBc_RS24210	COG1363	Peptidase, m42
BtBc_RS24220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BtBc_RS24235	COG0510	thiamine kinase activity
BtBc_RS24240	COG1523	belongs to the glycosyl hydrolase 13 family
BtBc_RS24250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BtBc_RS24255	COG1349	DNA-binding transcription factor activity
BtBc_RS24260	COG1187	pseudouridine synthase activity
BtBc_RS24265	COG2244	polysaccharide biosynthetic process
BtBc_RS24270	COG2081	HI0933 family
BtBc_RS24275	COG2814	Major facilitator Superfamily
BtBc_RS24285	COG3832	glyoxalase III activity
BtBc_RS24305	COG1329	Transcriptional regulator
BtBc_RS24330	COG0314	molybdopterin synthase activity
BtBc_RS24335	COG1763	Mo-molybdopterin cofactor biosynthetic process
BtBc_RS24340	COG0303	'Molybdopterin
BtBc_RS24350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BtBc_RS24355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BtBc_RS24375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BtBc_RS24385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BtBc_RS24430	COG2814	Major facilitator Superfamily
BtBc_RS24435	COG0475	glutathione-regulated potassium exporter activity
BtBc_RS24440	COG0490	domain, Protein
BtBc_RS24445	COG0582	viral genome integration into host DNA
BtBc_RS24455	COG1136	(ABC) transporter
BtBc_RS24475	COG1242	4 iron, 4 sulfur cluster binding
BtBc_RS24480	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BtBc_RS24485	COG1794	racemase activity, acting on amino acids and derivatives
BtBc_RS24505	COG2267	carboxylic ester hydrolase activity
BtBc_RS24510	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BtBc_RS24515	COG0671	phosphoesterase, PA-phosphatase related
BtBc_RS24520	COG0438	transferase activity, transferring glycosyl groups
BtBc_RS24545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS24585	COG0546	phosphoglycolate phosphatase activity
BtBc_RS24590	COG1349	DNA-binding transcription factor activity
BtBc_RS24600	COG5002	protein histidine kinase activity
BtBc_RS24605	COG3852	Histidine kinase
BtBc_RS24610	COG2267	carboxylic ester hydrolase activity
BtBc_RS24615	COG1368	sulfuric ester hydrolase activity
BtBc_RS24635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BtBc_RS24640	COG1116	anion transmembrane transporter activity
BtBc_RS24645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BtBc_RS24665	COG0494	nUDIX hydrolase
BtBc_RS24695	COG1854	S-ribosylhomocysteine lyase activity
BtBc_RS24705	COG0288	reversible hydration of carbon dioxide
BtBc_RS24710	COG1271	oxidase subunit
BtBc_RS24715	COG1294	oxidase, subunit
BtBc_RS24730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BtBc_RS24750	COG1842	Phage shock protein A
BtBc_RS24780	COG5002	protein histidine kinase activity
BtBc_RS24785	COG0745	RESPONSE REGULATOR receiver
BtBc_RS24810	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BtBc_RS24815	COG1597	lipid kinase activity
BtBc_RS24840	COG0586	Pfam SNARE associated Golgi protein
BtBc_RS24850	COG0577	efflux transmembrane transporter activity
BtBc_RS24855	COG1136	(ABC) transporter
BtBc_RS24860	COG2207	Transcriptional regulator
BtBc_RS24860	COG3708	Transcriptional regulator
BtBc_RS24870	COG5658	integral membrane protein
BtBc_RS24875	COG0640	Transcriptional regulator
BtBc_RS24880	COG0745	RESPONSE REGULATOR receiver
BtBc_RS24885	COG2205	protein histidine kinase activity
BtBc_RS24890	COG0577	efflux transmembrane transporter activity
BtBc_RS24895	COG0577	efflux transmembrane transporter activity
BtBc_RS24900	COG1136	(ABC) transporter
BtBc_RS24905	COG0577	efflux transmembrane transporter activity
BtBc_RS24935	COG2801	Transposase and inactivated derivatives
BtBc_RS24940	COG2188	Transcriptional regulator
BtBc_RS24960	COG3964	amidohydrolase
BtBc_RS24980	COG4948	Mandelate Racemase Muconate Lactonizing
BtBc_RS25000	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BtBc_RS25005	COG0596	Alpha beta hydrolase
BtBc_RS25015	COG1169	isochorismate synthase
BtBc_RS25020	COG1575	Belongs to the MenA family. Type 1 subfamily
BtBc_RS25025	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BtBc_RS25055	COG0058	SHG alpha-glucan phosphorylase activity
BtBc_RS25065	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BtBc_RS25185	COG0544	peptidyl-prolyl cis-trans isomerase activity
BtBc_RS25220	COG1285	pathogenesis
BtBc_RS25225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BtBc_RS25240	COG2155	Conserved Protein
BtBc_RS25245	COG1098	S1 RNA binding domain
BtBc_RS25250	COG0436	Aminotransferase
BtBc_RS25255	COG1522	sequence-specific DNA binding
BtBc_RS25260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BtBc_RS25265	COG2267	carboxylic ester hydrolase activity
BtBc_RS25275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BtBc_RS25295	COG5018	Exonuclease
BtBc_RS25300	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BtBc_RS25325	COG2801	Transposase and inactivated derivatives
BtBc_RS25330	COG2050	protein possibly involved in aromatic compounds catabolism
BtBc_RS25340	COG1268	BioY protein
BtBc_RS25345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BtBc_RS25350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BtBc_RS25365	COG3584	3D domain protein
BtBc_RS25380	COG1252	NADH dehydrogenase
BtBc_RS25395	COG3708	Transcriptional regulator
BtBc_RS25410	COG1683	Conserved Protein
BtBc_RS25470	COG1388	LysM domain
BtBc_RS25470	COG3409	Peptidoglycan-binding domain 1 protein
BtBc_RS25470	COG5632	N-Acetylmuramoyl-L-alanine amidase
BtBc_RS25475	COG4824	toxin secretion phage lysis holin
BtBc_RS25535	COG0740	serine-type endopeptidase activity
BtBc_RS25545	COG1802	Transcriptional regulator
BtBc_RS25545	COG4626	Terminase
BtBc_RS25660	COG1396	sequence-specific DNA binding
BtBc_RS25695	COG2963	transposase activity
BtBc_RS25700	COG2801	Transposase and inactivated derivatives
BtBc_RS25705	COG0316	Belongs to the HesB IscA family
BtBc_RS25720	COG1252	NADH dehydrogenase
BtBc_RS25735	COG0390	transport system, permease component
BtBc_RS25740	COG2824	Alkylphosphonate utilization operon protein PhnA
BtBc_RS25785	COG4837	Protein of unknown function (DUF1462)
BtBc_RS25790	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BtBc_RS25800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BtBc_RS25805	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BtBc_RS25825	COG1358	cellular component organization or biogenesis
BtBc_RS25835	COG2249	NAD(P)H dehydrogenase (quinone) activity
BtBc_RS25840	COG0647	UMP catabolic process
BtBc_RS25850	COG2445	Protein of unknown function DUF86
BtBc_RS25855	COG1494	fructose-1,6-bisphosphatase
BtBc_RS25875	COG4470	Protein conserved in bacteria
BtBc_RS25885	COG0789	Transcriptional regulator
BtBc_RS25890	COG4377	Putative membrane peptidase family (DUF2324)
BtBc_RS25915	COG0739	heme binding
BtBc_RS25925	COG3377	Domain of unknown function (DUF1805)
BtBc_RS25930	COG0737	Belongs to the 5'-nucleotidase family
BtBc_RS25935	COG0719	Fe-S assembly protein
BtBc_RS25940	COG0822	iron-sulfur transferase activity
BtBc_RS25945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BtBc_RS25950	COG0719	Fe-S assembly protein
BtBc_RS25955	COG0396	ATPase activity
BtBc_RS25960	COG1464	Belongs to the NlpA lipoprotein family
BtBc_RS25965	COG1464	Belongs to the NlpA lipoprotein family
BtBc_RS25970	COG2011	ABC-type metal ion transport system permease component
BtBc_RS25985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BtBc_RS25990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BtBc_RS26000	COG1393	Belongs to the ArsC family
BtBc_RS26020	COG0039	L-malate dehydrogenase activity
BtBc_RS26035	COG1309	transcriptional regulator
BtBc_RS26040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BtBc_RS26045	COG1960	acyl-CoA dehydrogenase activity
BtBc_RS26050	COG0183	Belongs to the thiolase family
BtBc_RS26055	COG1024	Enoyl-CoA hydratase
BtBc_RS26055	COG1250	3-hydroxyacyl-CoA dehydrogenase
BtBc_RS26065	COG1686	Belongs to the peptidase S11 family
BtBc_RS26080	COG0011	TIGRFAM Protein of
BtBc_RS26085	COG0840	transmembrane signaling receptor activity
BtBc_RS26100	COG2814	Major facilitator Superfamily
BtBc_RS26105	COG0531	amino acid
BtBc_RS26125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BtBc_RS26155	COG0586	Pfam SNARE associated Golgi protein
BtBc_RS26165	COG1376	ErfK ybiS ycfS ynhG family protein
BtBc_RS26170	COG0745	RESPONSE REGULATOR receiver
BtBc_RS26175	COG5002	protein histidine kinase activity
BtBc_RS26205	COG0840	transmembrane signaling receptor activity
BtBc_RS26210	COG2151	metal-sulfur cluster biosynthetic enzyme
BtBc_RS26215	COG3227	Zinc metalloprotease (Elastase)
BtBc_RS26235	COG0586	Pfam SNARE associated Golgi protein
BtBc_RS26240	COG0475	glutathione-regulated potassium exporter activity
BtBc_RS26245	COG0490	domain, Protein
BtBc_RS26250	COG1115	amino acid carrier protein
BtBc_RS26255	COG0783	Belongs to the Dps family
BtBc_RS26270	COG1611	Belongs to the LOG family
BtBc_RS26280	COG1528	Iron-storage protein
BtBc_RS26285	COG2311	Membrane
BtBc_RS26290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BtBc_RS26295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BtBc_RS26310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BtBc_RS26315	COG1115	amino acid carrier protein
BtBc_RS26320	COG1115	amino acid carrier protein
BtBc_RS26325	COG2910	NAD(P)H-binding
BtBc_RS26340	COG0656	L-ascorbic acid biosynthetic process
BtBc_RS26345	COG2814	Major facilitator Superfamily
BtBc_RS26350	COG1733	regulation of RNA biosynthetic process
BtBc_RS26360	COG1252	NADH dehydrogenase
BtBc_RS26415	COG0488	(ABC) transporter
BtBc_RS26420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BtBc_RS26470	COG0745	RESPONSE REGULATOR receiver
BtBc_RS26485	COG3344	reverse transcriptase
BtBc_RS26515	COG0557	exoribonuclease II activity
BtBc_RS26520	COG1647	Serine aminopeptidase, S33
BtBc_RS26525	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BtBc_RS26530	COG1346	cytolysis
BtBc_RS26565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BtBc_RS26580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BtBc_RS26610	COG0457	Tetratricopeptide repeat
BtBc_RS26615	COG1388	LysM domain
BtBc_RS26615	COG3409	Peptidoglycan-binding domain 1 protein
BtBc_RS26615	COG5632	N-Acetylmuramoyl-L-alanine amidase
BtBc_RS26620	COG3547	Transposase (IS116 IS110 IS902 family)
BtBc_RS26625	COG4824	toxin secretion phage lysis holin
BtBc_RS26630	COG3547	Transposase (IS116 IS110 IS902 family)
BtBc_RS26765	COG3331	DNA recombination
BtBc_RS26845	COG3646	Phage regulatory protein
BtBc_RS26870	COG0582	viral genome integration into host DNA
BtBc_RS26895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BtBc_RS26910	COG2323	membrane
BtBc_RS26920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BtBc_RS26930	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BtBc_RS26940	COG1051	belongs to the nudix hydrolase family
BtBc_RS26950	COG0492	ferredoxin-NADP+ reductase activity
BtBc_RS26955	COG0457	Tetratricopeptide repeat
BtBc_RS26960	COG0110	maltose O-acetyltransferase activity
BtBc_RS26980	COG1950	PFAM Membrane protein of
BtBc_RS26990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BtBc_RS26995	COG0556	nucleotide-excision repair
BtBc_RS27010	COG0789	Transcriptional regulator
BtBc_RS27030	COG0583	DNA-binding transcription factor activity
BtBc_RS27040	COG0655	NAD(P)H dehydrogenase (quinone) activity
BtBc_RS27045	COG0488	(ABC) transporter
BtBc_RS27055	COG1132	(ABC) transporter
BtBc_RS27060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BtBc_RS27065	COG3409	Peptidoglycan-binding domain 1 protein
BtBc_RS27065	COG0793	Belongs to the peptidase S41A family
BtBc_RS27070	COG2177	Part of the ABC transporter FtsEX involved in
BtBc_RS27075	COG2884	Cell division ATP-binding protein ftsE
BtBc_RS27085	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BtBc_RS27100	COG1131	(ABC) transporter
BtBc_RS27130	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BtBc_RS27135	COG1278	Cold shock
BtBc_RS27140	COG1040	competence protein
BtBc_RS27145	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BtBc_RS27150	COG1388	LysM domain
BtBc_RS27150	COG0791	NLP P60 protein
BtBc_RS27155	COG1733	regulation of RNA biosynthetic process
BtBc_RS27160	COG1307	EDD domain protein, DegV family
BtBc_RS27165	COG1739	Uncharacterized protein family UPF0029
BtBc_RS27170	COG1316	TRANSCRIPTIONal
BtBc_RS27175	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BtBc_RS27180	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BtBc_RS27185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BtBc_RS27195	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BtBc_RS27195	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BtBc_RS27215	COG1486	melibiose metabolic process
BtBc_RS27220	COG1447	Phosphotransferase system cellobiose-specific component IIA
BtBc_RS27225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BtBc_RS27235	COG1447	Phosphotransferase system cellobiose-specific component IIA
BtBc_RS27245	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BtBc_RS27250	COG1301	dicarboxylic acid transport
BtBc_RS27265	COG1511	domain protein
BtBc_RS27270	COG0583	DNA-binding transcription factor activity
BtBc_RS27275	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BtBc_RS27285	COG1271	oxidase subunit
BtBc_RS27290	COG1294	oxidase, subunit
BtBc_RS27295	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BtBc_RS27305	COG1620	l-lactate permease
BtBc_RS27320	COG2389	metal-binding protein
BtBc_RS27330	COG1368	sulfuric ester hydrolase activity
BtBc_RS27340	COG1388	LysM domain
BtBc_RS27340	COG0791	NLP P60 protein
BtBc_RS27345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BtBc_RS27355	COG1215	transferase activity, transferring glycosyl groups
BtBc_RS27365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BtBc_RS27370	COG1388	LysM domain
BtBc_RS27370	COG3584	3D domain protein
BtBc_RS27395	COG4715	Zinc finger, swim domain protein
BtBc_RS27400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BtBc_RS27440	COG0577	efflux transmembrane transporter activity
BtBc_RS27445	COG1136	(ABC) transporter
BtBc_RS27470	COG5002	protein histidine kinase activity
BtBc_RS27475	COG0745	RESPONSE REGULATOR receiver
BtBc_RS27485	COG1316	TRANSCRIPTIONal
BtBc_RS27490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BtBc_RS27495	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BtBc_RS27500	COG1215	transferase activity, transferring glycosyl groups
BtBc_RS27505	COG0463	Glycosyl transferase, family 2
BtBc_RS27510	COG0438	transferase activity, transferring glycosyl groups
BtBc_RS27520	COG1216	Glycosyl transferase, family 2
BtBc_RS27535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BtBc_RS27540	COG4464	protein tyrosine phosphatase activity
BtBc_RS27545	COG0489	protein tyrosine kinase activity
BtBc_RS27550	COG3944	biosynthesis protein
BtBc_RS27555	COG0489	protein tyrosine kinase activity
BtBc_RS27570	COG1609	Transcriptional regulator
BtBc_RS27580	COG0739	heme binding
BtBc_RS27595	COG3279	Response regulator of the LytR AlgR family
BtBc_RS27600	COG2385	sporulation resulting in formation of a cellular spore
BtBc_RS27615	COG4836	Membrane
BtBc_RS27620	COG1007	ATP synthesis coupled electron transport
BtBc_RS27625	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BtBc_RS27630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BtBc_RS27640	COG0839	Belongs to the complex I subunit 6 family
BtBc_RS27660	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BtBc_RS27725	COG0356	it plays a direct role in the translocation of protons across the membrane
BtBc_RS27760	COG0698	ribose 5-phosphate isomerase
BtBc_RS27775	COG2259	Doxx family
BtBc_RS27780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BtBc_RS27800	COG0009	L-threonylcarbamoyladenylate synthase
BtBc_RS27835	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BtBc_RS27840	COG1494	fructose-1,6-bisphosphatase
BtBc_RS27860	COG4821	SIS domain
BtBc_RS27870	COG3343	RNA polymerase activity
BtBc_RS27880	COG1960	acyl-CoA dehydrogenase activity
BtBc_RS27885	COG1960	acyl-CoA dehydrogenase activity
BtBc_RS27890	COG1250	3-hydroxyacyl-CoA dehydrogenase
BtBc_RS27895	COG0183	Belongs to the thiolase family
BtBc_RS27900	COG0247	lactate metabolic process
BtBc_RS27900	COG2181	nitrate reductase activity
BtBc_RS27905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BtBc_RS27920	COG3344	reverse transcriptase
BtBc_RS27940	COG3300	MHYT domain
BtBc_RS27940	COG5001	Diguanylate cyclase
BtBc_RS27955	COG3227	Zinc metalloprotease (Elastase)
BtBc_RS27960	COG2197	response regulator
BtBc_RS27965	COG4585	Histidine kinase
BtBc_RS27970	COG0842	Transport permease protein
BtBc_RS27975	COG1131	(ABC) transporter
BtBc_RS27980	COG0024	Methionine aminopeptidase
BtBc_RS27990	COG2234	aminopeptidase activity
BtBc_RS27995	COG2801	Transposase and inactivated derivatives
BtBc_RS28020	COG1595	DNA-templated transcription, initiation
BtBc_RS28030	COG4506	Protein conserved in bacteria
BtBc_RS28035	COG1619	proteins homologs of microcin C7 resistance protein MccF
BtBc_RS28060	COG2814	Major facilitator Superfamily
BtBc_RS28065	COG0789	Transcriptional regulator
BtBc_RS28070	COG0584	glycerophosphoryl diester phosphodiesterase
BtBc_RS28075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BtBc_RS28085	COG1994	Peptidase M50
BtBc_RS28095	COG1078	dGTPase activity
BtBc_RS28100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BtBc_RS28105	COG1120	ATPase activity
BtBc_RS28110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BtBc_RS28115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BtBc_RS28135	COG0280	phosphate acetyltransferase
BtBc_RS28150	COG3773	Cell wall hydrolase
BtBc_RS28160	COG2363	Small membrane protein
BtBc_RS28170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BtBc_RS28175	COG2233	PERMEase
BtBc_RS28180	COG0561	phosphatase activity
BtBc_RS28185	COG2814	Major facilitator Superfamily
BtBc_RS28195	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BtBc_RS28200	COG1131	(ABC) transporter
BtBc_RS28205	COG2755	lipolytic protein G-D-S-L family
BtBc_RS28210	COG1609	Transcriptional regulator
BtBc_RS28220	COG0460	homoserine dehydrogenase
BtBc_RS28230	COG2873	o-acetylhomoserine
BtBc_RS28240	COG1011	Hydrolase
BtBc_RS28245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BtBc_RS28255	COG2197	response regulator
BtBc_RS28260	COG2203	Gaf domain
BtBc_RS28260	COG4585	Histidine kinase
BtBc_RS28265	COG0351	phosphomethylpyrimidine kinase
BtBc_RS28270	COG3706	GGDEF domain
BtBc_RS28275	COG2879	small protein
BtBc_RS28280	COG1966	Carbon starvation protein
BtBc_RS28285	COG3279	Response regulator of the LytR AlgR family
BtBc_RS28290	COG0477	Major facilitator Superfamily
BtBc_RS28300	COG0438	transferase activity, transferring glycosyl groups
BtBc_RS28315	COG0840	transmembrane signaling receptor activity
BtBc_RS28325	COG1607	acyl-coa hydrolase
BtBc_RS28330	COG1216	Glycosyl transferase, family 2
BtBc_RS28345	COG1216	Glycosyl transferase, family 2
BtBc_RS28360	COG0463	Glycosyl transferase, family 2
BtBc_RS28365	COG0488	(ABC) transporter
BtBc_RS28370	COG1309	transcriptional regulator
BtBc_RS28375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BtBc_RS28380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BtBc_RS28380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BtBc_RS28385	COG0628	permease
BtBc_RS28405	COG3275	phosphorelay sensor kinase activity
BtBc_RS28410	COG2814	Major facilitator Superfamily
BtBc_RS28415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BtBc_RS28420	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BtBc_RS28440	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BtBc_RS28445	COG1272	protein, Hemolysin III
BtBc_RS28465	COG3344	reverse transcriptase
BtBc_RS28505	COG5002	protein histidine kinase activity
BtBc_RS28520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BtBc_RS28525	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BtBc_RS28530	COG4853	Protein conserved in bacteria
BtBc_RS28540	COG5002	protein histidine kinase activity
BtBc_RS28545	COG0745	RESPONSE REGULATOR receiver
BtBc_RS28575	COG0305	Participates in initiation and elongation during chromosome replication
BtBc_RS28585	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BtBc_RS28590	COG4241	membrane
BtBc_RS28610	COG0012	GTP binding
BtBc_RS28615	COG4481	Protein conserved in bacteria
BtBc_RS28620	COG0668	transmembrane transport
BtBc_RS28630	COG1475	DNA binding
BtBc_RS28635	COG1192	Involved in chromosome partitioning
BtBc_RS28660	COG1847	R3H domain protein
BtBc_RS28675	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BtBc_RS28715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BtBc_RS29010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BtBc_RS29035	COG2244	polysaccharide biosynthetic process
BtBc_RS29075	COG2208	phosphoserine phosphatase activity
BtBc_RS29435	COG0489	protein tyrosine kinase activity
BtBc_RS29615	COG0516	GMP reductase activity
BtBc_RS29615	COG0517	IMP dehydrogenase activity
BtBc_RS29625	COG1686	Belongs to the peptidase S11 family
BtBc_RS29665	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BtBc_RS29755	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BtBc_RS29800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BtBc_RS29855	COG0516	GMP reductase activity
BtBc_RS29855	COG0517	IMP dehydrogenase activity
BtBc_RS30060	COG2244	polysaccharide biosynthetic process
BtBc_RS30095	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BtBc_RS30110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BtBc_RS30150	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BtBc_RS30450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BtBc_RS30555	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BtBc_RS30715	COG0517	IMP dehydrogenase activity
BtBc_RS30715	COG0516	GMP reductase activity
BtBc_RS30945	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BtBc_RS30965	COG2244	polysaccharide biosynthetic process
BtBc_RS30975	COG3956	TIGRFAM MazG family protein