locus-tag	class	description
BTI247_RS00010	COG0592	DNA-directed DNA polymerase activity
BTI247_RS00015	COG2501	S4 domain
BTI247_RS00025	COG0187	DNA topoisomerase II activity
BTI247_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTI247_RS00065	COG0516	GMP reductase activity
BTI247_RS00065	COG0517	IMP dehydrogenase activity
BTI247_RS00070	COG1686	Belongs to the peptidase S11 family
BTI247_RS00100	COG1428	Deoxynucleoside kinase
BTI247_RS00105	COG1428	Deoxynucleoside kinase
BTI247_RS00110	COG1335	isochorismatase
BTI247_RS00115	COG0590	tRNA wobble adenosine to inosine editing
BTI247_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTI247_RS00180	COG1982	Orn Lys Arg decarboxylase major
BTI247_RS00190	COG0470	DNA polymerase III
BTI247_RS00195	COG1774	PSP1 C-terminal conserved region
BTI247_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BTI247_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BTI247_RS00220	COG2002	toxin-antitoxin pair type II binding
BTI247_RS00230	COG0084	hydrolase, TatD family'
BTI247_RS00250	COG4466	Protein conserved in bacteria
BTI247_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BTI247_RS00270	COG0251	oxidation-reduction process
BTI247_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTI247_RS00305	COG2002	toxin-antitoxin pair type II binding
BTI247_RS00310	COG2244	polysaccharide biosynthetic process
BTI247_RS00315	COG3956	TIGRFAM MazG family protein
BTI247_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BTI247_RS00340	COG1098	S1 RNA binding domain
BTI247_RS00355	COG2208	phosphoserine phosphatase activity
BTI247_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTI247_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTI247_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTI247_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BTI247_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
BTI247_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTI247_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BTI247_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BTI247_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BTI247_RS00420	COG1396	sequence-specific DNA binding
BTI247_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTI247_RS00515	COG3880	PFAM UvrB UvrC protein
BTI247_RS00525	COG0542	response to heat
BTI247_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BTI247_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
BTI247_RS00560	COG1045	serine acetyltransferase
BTI247_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTI247_RS00580	COG3688	RNA-binding protein containing a PIN domain
BTI247_RS00590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTI247_RS00595	COG0250	Participates in transcription elongation, termination and antitermination
BTI247_RS00600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BTI247_RS00615	COG0222	ribosome binding
BTI247_RS00620	COG2813	Specifically methylates the guanine in position
BTI247_RS00630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BTI247_RS00635	COG1358	cellular component organization or biogenesis
BTI247_RS00640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BTI247_RS00660	COG0051	transcription antitermination factor activity, RNA binding
BTI247_RS00665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BTI247_RS00705	COG0255	Belongs to the universal ribosomal protein uL29 family
BTI247_RS00765	COG0201	protein transport
BTI247_RS00775	COG0024	Methionine aminopeptidase
BTI247_RS00785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BTI247_RS00820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BTI247_RS00845	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTI247_RS00850	COG0489	protein tyrosine kinase activity
BTI247_RS00860	COG2194	sulfuric ester hydrolase activity
BTI247_RS00865	COG0726	polysaccharide deacetylase
BTI247_RS00945	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BTI247_RS00950	COG4856	YbbR-like protein
BTI247_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS00995	COG2011	ABC-type metal ion transport system permease component
BTI247_RS01000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BTI247_RS01005	COG1464	Belongs to the NlpA lipoprotein family
BTI247_RS01010	COG0604	alcohol dehydrogenase
BTI247_RS01020	COG0277	FAD linked oxidase domain protein
BTI247_RS01025	COG2271	Major facilitator Superfamily
BTI247_RS01035	COG2814	Major facilitator Superfamily
BTI247_RS01055	COG0601	transmembrane transport
BTI247_RS01060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTI247_RS01065	COG0444	Belongs to the ABC transporter superfamily
BTI247_RS01070	COG4608	Belongs to the ABC transporter superfamily
BTI247_RS01075	COG4166	transmembrane transport
BTI247_RS01090	COG4166	transmembrane transport
BTI247_RS01095	COG4166	transmembrane transport
BTI247_RS01100	COG0656	L-ascorbic acid biosynthetic process
BTI247_RS01120	COG4149	molybdate abc transporter
BTI247_RS01125	COG0725	ABC transporter, periplasmic molybdate-binding protein
BTI247_RS01130	COG1910	domain protein
BTI247_RS01145	COG0697	spore germination
BTI247_RS01155	COG0204	Acyl-transferase
BTI247_RS01165	COG1609	Transcriptional regulator
BTI247_RS01175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTI247_RS01195	COG5298	Protein conserved in bacteria
BTI247_RS01215	COG0488	(ABC) transporter
BTI247_RS01225	COG0747	negative chemotaxis
BTI247_RS01230	COG0601	transmembrane transport
BTI247_RS01235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTI247_RS01240	COG0444	Belongs to the ABC transporter superfamily
BTI247_RS01245	COG4608	Belongs to the ABC transporter superfamily
BTI247_RS01250	COG0561	phosphatase activity
BTI247_RS01280	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BTI247_RS01285	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTI247_RS01295	COG0531	amino acid
BTI247_RS01300	COG2814	Major facilitator Superfamily
BTI247_RS01310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BTI247_RS01320	COG4294	response to UV
BTI247_RS01325	COG0705	Rhomboid family
BTI247_RS01335	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BTI247_RS01340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTI247_RS01345	COG0864	Transcriptional regulator
BTI247_RS01350	COG2337	Toxic component of a toxin-antitoxin (TA) module
BTI247_RS01355	COG2183	response to ionizing radiation
BTI247_RS01450	COG0802	atpase or kinase
BTI247_RS01455	COG1214	PFAM Peptidase M22, glycoprotease
BTI247_RS01460	COG0456	acetyltransferase
BTI247_RS01470	COG0488	(ABC) transporter
BTI247_RS01485	COG1266	CAAX protease self-immunity
BTI247_RS01500	COG5444	nuclease activity
BTI247_RS01515	COG2252	PERMEase
BTI247_RS01525	COG5002	protein histidine kinase activity
BTI247_RS01550	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BTI247_RS01570	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS01590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTI247_RS01595	COG0506	proline dehydrogenase activity
BTI247_RS01635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTI247_RS01670	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS01675	COG0297	glycogen (starch) synthase activity
BTI247_RS01675	COG0438	transferase activity, transferring glycosyl groups
BTI247_RS01695	COG0697	spore germination
BTI247_RS01720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTI247_RS01725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BTI247_RS01730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTI247_RS01740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTI247_RS01755	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BTI247_RS01765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BTI247_RS01775	COG0151	Belongs to the GarS family
BTI247_RS01800	COG0210	DNA helicase
BTI247_RS01810	COG4851	CamS sex pheromone cAM373 precursor
BTI247_RS01830	COG1335	isochorismatase
BTI247_RS01840	COG2011	ABC-type metal ion transport system permease component
BTI247_RS01845	COG1464	Belongs to the NlpA lipoprotein family
BTI247_RS01855	COG0003	Pfam Anion-transporting ATPase
BTI247_RS01860	COG1846	Transcriptional regulator
BTI247_RS01865	COG4682	membrane
BTI247_RS01885	COG1597	lipid kinase activity
BTI247_RS01895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTI247_RS01905	COG1012	belongs to the aldehyde dehydrogenase family
BTI247_RS01910	COG2076	Multidrug Resistance protein
BTI247_RS01920	COG2309	aminopeptidase activity
BTI247_RS01930	COG0582	viral genome integration into host DNA
BTI247_RS01940	COG1396	sequence-specific DNA binding
BTI247_RS01985	COG3617	BRO family, N-terminal domain
BTI247_RS02000	COG0582	viral genome integration into host DNA
BTI247_RS02165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTI247_RS02175	COG0582	viral genome integration into host DNA
BTI247_RS02195	COG3620	sequence-specific DNA binding
BTI247_RS02245	COG2002	toxin-antitoxin pair type II binding
BTI247_RS02305	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS02320	COG0582	viral genome integration into host DNA
BTI247_RS02325	COG1674	ftsk spoiiie
BTI247_RS02325	COG4980	gas vesicle protein
BTI247_RS02345	COG5484	DNA packaging
BTI247_RS02420	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS02435	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS02445	COG4824	toxin secretion phage lysis holin
BTI247_RS02455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTI247_RS02470	COG4807	Protein conserved in bacteria
BTI247_RS02495	COG1757	Na H antiporter
BTI247_RS02500	COG1473	amidohydrolase
BTI247_RS02515	COG0450	alkyl hydroperoxide reductase
BTI247_RS02535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTI247_RS02540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTI247_RS02545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTI247_RS02550	COG0492	ferredoxin-NADP+ reductase activity
BTI247_RS02560	COG0166	Belongs to the GPI family
BTI247_RS02585	COG4191	Histidine kinase
BTI247_RS02590	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS02595	COG5002	protein histidine kinase activity
BTI247_RS02615	COG3541	Predicted nucleotidyltransferase
BTI247_RS02620	COG2814	Major facilitator Superfamily
BTI247_RS02625	COG0723	plastoquinol--plastocyanin reductase activity
BTI247_RS02625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTI247_RS02630	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS02640	COG0765	amino acid transport
BTI247_RS02645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTI247_RS02650	COG1126	abc transporter atp-binding protein
BTI247_RS02655	COG0840	transmembrane signaling receptor activity
BTI247_RS02680	COG0549	Belongs to the carbamate kinase family
BTI247_RS02685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTI247_RS02695	COG0277	FAD linked oxidase domain protein
BTI247_RS02700	COG0366	Alpha amylase catalytic
BTI247_RS02705	COG2190	(PTS) system
BTI247_RS02705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTI247_RS02705	COG1263	PTS System
BTI247_RS02735	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BTI247_RS02755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTI247_RS02760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTI247_RS02765	COG1116	anion transmembrane transporter activity
BTI247_RS02770	COG0488	(ABC) transporter
BTI247_RS02815	COG2270	Major facilitator Superfamily
BTI247_RS02840	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS02850	COG2310	stress, protein
BTI247_RS02855	COG2310	stress, protein
BTI247_RS02860	COG2310	stress, protein
BTI247_RS02865	COG0861	Integral membrane protein TerC family
BTI247_RS02875	COG3853	Toxic anion resistance protein (TelA)
BTI247_RS02890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BTI247_RS02900	COG1295	ribonuclease BN
BTI247_RS02905	COG2217	Heavy metal translocating P-type atpase
BTI247_RS02910	COG0697	spore germination
BTI247_RS02930	COG0586	Pfam SNARE associated Golgi protein
BTI247_RS02945	COG3871	stress protein (general stress protein 26)
BTI247_RS02950	COG0387	Pfam Sodium calcium exchanger
BTI247_RS02960	COG0535	radical SAM domain protein
BTI247_RS02980	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BTI247_RS02985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BTI247_RS03000	COG3829	transcription factor binding
BTI247_RS03010	COG0833	amino acid
BTI247_RS03015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTI247_RS03040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTI247_RS03040	COG1263	PTS System
BTI247_RS03045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTI247_RS03060	COG1216	Glycosyl transferase, family 2
BTI247_RS03070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTI247_RS03070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTI247_RS03075	COG0463	Glycosyl transferase, family 2
BTI247_RS03085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BTI247_RS03105	COG1228	amidohydrolase
BTI247_RS03110	COG1090	epimerase
BTI247_RS03140	COG1988	membrane-bound metal-dependent
BTI247_RS03145	COG1194	a g-specific adenine glycosylase
BTI247_RS03165	COG3557	Belongs to the UPF0374 family
BTI247_RS03170	COG1132	(ABC) transporter
BTI247_RS03175	COG4129	membrane
BTI247_RS03180	COG0067	glutamate synthase
BTI247_RS03180	COG0069	glutamate synthase activity
BTI247_RS03180	COG0070	glutamate synthase
BTI247_RS03190	COG4555	ABC transporter
BTI247_RS03210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTI247_RS03215	COG0735	belongs to the Fur family
BTI247_RS03335	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BTI247_RS03360	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BTI247_RS03370	COG2766	serine protein kinase
BTI247_RS03390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTI247_RS03400	COG1585	Membrane protein implicated in regulation of membrane protease activity
BTI247_RS03405	COG2268	Band 7 protein
BTI247_RS03415	COG3290	protein histidine kinase activity
BTI247_RS03420	COG4565	transcriptional regulatory protein
BTI247_RS03425	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS03430	COG2851	Citrate transporter
BTI247_RS03450	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS03460	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BTI247_RS03465	COG3842	ATPase activity
BTI247_RS03470	COG1175	transmembrane transport
BTI247_RS03475	COG0395	ABC-type sugar transport system, permease component
BTI247_RS03485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BTI247_RS03490	COG0745	RESPONSE REGULATOR receiver
BTI247_RS03495	COG5002	protein histidine kinase activity
BTI247_RS03505	COG4990	cell redox homeostasis
BTI247_RS03515	COG3290	protein histidine kinase activity
BTI247_RS03520	COG4565	transcriptional regulatory protein
BTI247_RS03525	COG3493	citrate carrier protein
BTI247_RS03530	COG0281	malic enzyme
BTI247_RS03540	COG0697	spore germination
BTI247_RS03545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTI247_RS03550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTI247_RS03560	COG5002	protein histidine kinase activity
BTI247_RS03565	COG0745	RESPONSE REGULATOR receiver
BTI247_RS03580	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTI247_RS03585	COG3383	formate dehydrogenase (NAD+) activity
BTI247_RS03590	COG2427	Protein of unknown function (DUF1641)
BTI247_RS03605	COG0531	amino acid
BTI247_RS03615	COG0640	Transcriptional regulator
BTI247_RS03620	COG2217	Heavy metal translocating P-type atpase
BTI247_RS03625	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BTI247_RS03635	COG3227	Zinc metalloprotease (Elastase)
BTI247_RS03655	COG2720	vancomycin resistance protein
BTI247_RS03660	COG1316	TRANSCRIPTIONal
BTI247_RS03665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTI247_RS03670	COG0346	lactoylglutathione lyase activity
BTI247_RS03675	COG1253	flavin adenine dinucleotide binding
BTI247_RS03680	COG1027	Aspartate ammonia-lyase
BTI247_RS03685	COG1620	l-lactate permease
BTI247_RS03700	COG3104	oligopeptide transport
BTI247_RS03705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTI247_RS03710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTI247_RS03715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTI247_RS03730	COG0156	8-amino-7-oxononanoate synthase activity
BTI247_RS03735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTI247_RS03745	COG4548	von Willebrand factor, type A
BTI247_RS03750	COG0714	Associated with various cellular activities
BTI247_RS03770	COG0531	amino acid
BTI247_RS03775	COG2188	Transcriptional regulator
BTI247_RS03780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTI247_RS03780	COG1263	PTS System
BTI247_RS03785	COG0366	Alpha amylase catalytic
BTI247_RS03800	COG0697	spore germination
BTI247_RS03805	COG4585	Histidine kinase
BTI247_RS03810	COG2197	response regulator
BTI247_RS03815	COG1404	Belongs to the peptidase S8 family
BTI247_RS03825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTI247_RS03830	COG1115	amino acid carrier protein
BTI247_RS03835	COG1126	abc transporter atp-binding protein
BTI247_RS03840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTI247_RS03845	COG0765	amino acid transport
BTI247_RS03850	COG0765	amino acid transport
BTI247_RS03855	COG0833	amino acid
BTI247_RS03870	COG2378	regulation of single-species biofilm formation
BTI247_RS03875	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BTI247_RS03880	COG5002	protein histidine kinase activity
BTI247_RS03895	COG0659	secondary active sulfate transmembrane transporter activity
BTI247_RS03910	COG0747	negative chemotaxis
BTI247_RS03920	COG0601	transmembrane transport
BTI247_RS03925	COG4608	Belongs to the ABC transporter superfamily
BTI247_RS03935	COG2271	Major facilitator Superfamily
BTI247_RS03940	COG1846	Transcriptional regulator
BTI247_RS03945	COG0477	Major facilitator Superfamily
BTI247_RS03950	COG1609	Transcriptional regulator
BTI247_RS03955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTI247_RS03970	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTI247_RS03975	COG1879	ABC-type sugar transport system periplasmic component
BTI247_RS03990	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS04015	COG1063	alcohol dehydrogenase
BTI247_RS04140	COG0582	viral genome integration into host DNA
BTI247_RS04170	COG1802	Transcriptional regulator
BTI247_RS04170	COG4626	Terminase
BTI247_RS04180	COG0740	serine-type endopeptidase activity
BTI247_RS04225	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS04250	COG4824	toxin secretion phage lysis holin
BTI247_RS04275	COG1674	ftsk spoiiie
BTI247_RS04320	COG0840	transmembrane signaling receptor activity
BTI247_RS04325	COG1388	LysM domain
BTI247_RS04325	COG3584	3D domain protein
BTI247_RS04330	COG1476	TRANSCRIPTIONal
BTI247_RS04350	COG3104	oligopeptide transport
BTI247_RS04355	COG1114	Component of the transport system for branched-chain amino acids
BTI247_RS04370	COG1113	amino acid transport
BTI247_RS04375	COG2252	PERMEase
BTI247_RS04400	COG2153	protein acetylation
BTI247_RS04410	COG0569	domain protein
BTI247_RS04410	COG0475	glutathione-regulated potassium exporter activity
BTI247_RS04425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTI247_RS04435	COG0833	amino acid
BTI247_RS04440	COG4990	cell redox homeostasis
BTI247_RS04455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTI247_RS04460	COG0697	spore germination
BTI247_RS04465	COG0531	amino acid
BTI247_RS04475	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTI247_RS04480	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTI247_RS04485	COG1918	ferrous iron import across plasma membrane
BTI247_RS04485	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTI247_RS04490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BTI247_RS04495	COG0573	inorganic phosphate transmembrane transporter activity
BTI247_RS04500	COG0581	inorganic phosphate transmembrane transporter activity
BTI247_RS04510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTI247_RS04630	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BTI247_RS04650	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BTI247_RS04655	COG1116	anion transmembrane transporter activity
BTI247_RS04665	COG2801	Transposase and inactivated derivatives
BTI247_RS04680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTI247_RS04685	COG0352	thiamine-phosphate diphosphorylase activity
BTI247_RS04690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTI247_RS04695	COG2104	thiamine diphosphate biosynthetic process
BTI247_RS04705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTI247_RS04710	COG0351	phosphomethylpyrimidine kinase
BTI247_RS04750	COG2205	protein histidine kinase activity
BTI247_RS04755	COG2814	Major facilitator Superfamily
BTI247_RS04760	COG1846	Transcriptional regulator
BTI247_RS04775	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTI247_RS04780	COG1129	ABC transporter
BTI247_RS04785	COG1879	ABC-type sugar transport system periplasmic component
BTI247_RS04790	COG2252	PERMEase
BTI247_RS04795	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS04855	COG0778	Nitroreductase
BTI247_RS04860	COG2719	SpoVR family
BTI247_RS04865	COG1401	restriction endodeoxyribonuclease activity
BTI247_RS04875	COG0446	pyridine nucleotide-disulphide oxidoreductase
BTI247_RS04880	COG1937	Protein conserved in bacteria
BTI247_RS04885	COG0425	Belongs to the sulfur carrier protein TusA family
BTI247_RS04885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTI247_RS04890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTI247_RS04890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTI247_RS04895	COG0425	Belongs to the sulfur carrier protein TusA family
BTI247_RS04910	COG2210	Belongs to the sulfur carrier protein TusA family
BTI247_RS04915	COG0730	response to heat
BTI247_RS04925	COG1316	TRANSCRIPTIONal
BTI247_RS04930	COG0604	alcohol dehydrogenase
BTI247_RS04950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTI247_RS04950	COG3711	transcriptional antiterminator
BTI247_RS04955	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTI247_RS04960	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTI247_RS04980	COG3584	3D domain protein
BTI247_RS04980	COG1388	LysM domain
BTI247_RS04985	COG0577	efflux transmembrane transporter activity
BTI247_RS04990	COG1136	(ABC) transporter
BTI247_RS05000	COG5522	Integral membrane protein (intg_mem_TP0381)
BTI247_RS05015	COG1114	Component of the transport system for branched-chain amino acids
BTI247_RS05020	COG3546	catalase activity
BTI247_RS05055	COG0586	Pfam SNARE associated Golgi protein
BTI247_RS05085	COG0531	amino acid
BTI247_RS05090	COG0475	glutathione-regulated potassium exporter activity
BTI247_RS05100	COG1737	Transcriptional regulator
BTI247_RS05120	COG2259	Doxx family
BTI247_RS05140	COG1522	sequence-specific DNA binding
BTI247_RS05145	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS05155	COG0300	oxidoreductase activity
BTI247_RS05175	COG1309	transcriptional regulator
BTI247_RS05180	COG2814	Major facilitator Superfamily
BTI247_RS05185	COG1733	regulation of RNA biosynthetic process
BTI247_RS05195	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTI247_RS05205	COG4533	DNA binding
BTI247_RS05210	COG2211	Major facilitator Superfamily
BTI247_RS05220	COG0693	protein deglycase activity
BTI247_RS05230	COG0531	amino acid
BTI247_RS05245	COG1012	belongs to the aldehyde dehydrogenase family
BTI247_RS05250	COG1132	(ABC) transporter
BTI247_RS05255	COG1132	(ABC) transporter
BTI247_RS05260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTI247_RS05265	COG0765	amino acid transport
BTI247_RS05270	COG1126	abc transporter atp-binding protein
BTI247_RS05285	COG0189	ligase activity
BTI247_RS05320	COG0028	Belongs to the TPP enzyme family
BTI247_RS05325	COG3527	Alpha-acetolactate decarboxylase
BTI247_RS05335	COG0561	phosphatase activity
BTI247_RS05350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTI247_RS05355	COG0318	PFAM AMP-dependent synthetase and ligase
BTI247_RS05370	COG0659	secondary active sulfate transmembrane transporter activity
BTI247_RS05375	COG2244	polysaccharide biosynthetic process
BTI247_RS05395	COG1024	Enoyl-CoA hydratase
BTI247_RS05415	COG1363	Peptidase, m42
BTI247_RS05455	COG0601	transmembrane transport
BTI247_RS05460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTI247_RS05465	COG0444	Belongs to the ABC transporter superfamily
BTI247_RS05470	COG4608	Belongs to the ABC transporter superfamily
BTI247_RS05480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTI247_RS05495	COG0477	Major facilitator Superfamily
BTI247_RS05500	COG3290	protein histidine kinase activity
BTI247_RS05505	COG4565	transcriptional regulatory protein
BTI247_RS05510	COG3181	Tripartite tricarboxylate transporter family receptor
BTI247_RS05540	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BTI247_RS05550	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BTI247_RS05625	COG0305	Participates in initiation and elongation during chromosome replication
BTI247_RS05650	COG0477	Major facilitator Superfamily
BTI247_RS05665	COG1073	alpha beta
BTI247_RS05700	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS05710	COG1183	phosphatidylcholine synthase activity
BTI247_RS05720	COG2814	Major facilitator Superfamily
BTI247_RS05725	COG0640	Transcriptional regulator
BTI247_RS05735	COG2376	Dihydroxyacetone kinase
BTI247_RS05745	COG2376	Dihydroxyacetone kinase
BTI247_RS05775	COG2373	Large extracellular alpha-helical protein
BTI247_RS05825	COG3237	CsbD-like
BTI247_RS05850	COG1191	sigma factor activity
BTI247_RS05860	COG2208	phosphoserine phosphatase activity
BTI247_RS05865	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTI247_RS05875	COG2801	Transposase and inactivated derivatives
BTI247_RS05915	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BTI247_RS05935	COG0420	3'-5' exonuclease activity
BTI247_RS05940	COG4717	serine-type aminopeptidase activity
BTI247_RS05950	COG4974	Belongs to the 'phage' integrase family
BTI247_RS06060	COG0582	viral genome integration into host DNA
BTI247_RS06165	COG4824	toxin secretion phage lysis holin
BTI247_RS06170	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTI247_RS06170	COG1388	LysM domain
BTI247_RS06170	COG3409	Peptidoglycan-binding domain 1 protein
BTI247_RS06210	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS06215	COG1280	lysine exporter protein (LysE YggA)
BTI247_RS06220	COG0346	lactoylglutathione lyase activity
BTI247_RS06225	COG0346	lactoylglutathione lyase activity
BTI247_RS06230	COG0457	Tetratricopeptide repeat
BTI247_RS06240	COG2267	carboxylic ester hydrolase activity
BTI247_RS06255	COG2140	Oxalate decarboxylase
BTI247_RS06260	COG3620	sequence-specific DNA binding
BTI247_RS06265	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BTI247_RS06270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BTI247_RS06280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BTI247_RS06305	COG1595	DNA-templated transcription, initiation
BTI247_RS06320	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS06330	COG3973	AAA domain
BTI247_RS06360	COG4980	gas vesicle protein
BTI247_RS06365	COG0537	adenosine 5'-monophosphoramidase activity
BTI247_RS06370	COG1131	(ABC) transporter
BTI247_RS06375	COG4473	ABC transporter
BTI247_RS06405	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS06415	COG1309	transcriptional regulator
BTI247_RS06425	COG3402	PFAM membrane-flanked domain
BTI247_RS06430	COG3428	Bacterial PH domain
BTI247_RS06480	COG0697	spore germination
BTI247_RS06485	COG3402	PFAM membrane-flanked domain
BTI247_RS06490	COG3428	Bacterial PH domain
BTI247_RS06495	COG2329	Antibiotic biosynthesis monooxygenase
BTI247_RS06500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTI247_RS06515	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BTI247_RS06550	COG1309	transcriptional regulator
BTI247_RS06555	COG1511	domain protein
BTI247_RS06580	COG1609	Transcriptional regulator
BTI247_RS06590	COG1234	tRNA 3'-trailer cleavage
BTI247_RS06595	COG0095	Lipoate-protein ligase
BTI247_RS06605	COG0318	PFAM AMP-dependent synthetase and ligase
BTI247_RS06615	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BTI247_RS06625	COG4208	sulfate ABC transporter
BTI247_RS06650	COG3209	COG3209 Rhs family protein
BTI247_RS06705	COG1408	metallophosphoesterase
BTI247_RS06715	COG1078	dGTPase activity
BTI247_RS06725	COG1595	DNA-templated transcription, initiation
BTI247_RS06730	COG3708	Transcriptional regulator
BTI247_RS06730	COG2207	Transcriptional regulator
BTI247_RS06745	COG0745	RESPONSE REGULATOR receiver
BTI247_RS06765	COG0501	Belongs to the peptidase M48B family
BTI247_RS06770	COG0840	transmembrane signaling receptor activity
BTI247_RS06775	COG3693	PFAM glycoside hydrolase, family 10
BTI247_RS06785	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BTI247_RS06790	COG2224	Isocitrate lyase
BTI247_RS06830	COG4903	ComK protein
BTI247_RS06835	COG0398	Pfam SNARE associated Golgi protein
BTI247_RS06855	COG0202	RNA polymerase activity
BTI247_RS06895	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTI247_RS06920	COG0367	asparagine synthase
BTI247_RS06930	COG0753	catalase activity
BTI247_RS06935	COG0004	ammonium transporteR
BTI247_RS06955	COG2996	Protein conserved in bacteria
BTI247_RS06990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTI247_RS07005	COG0561	phosphatase activity
BTI247_RS07025	COG2267	carboxylic ester hydrolase activity
BTI247_RS07040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTI247_RS07045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTI247_RS07050	COG5504	Zn-dependent protease
BTI247_RS07060	COG0180	Tryptophanyl-tRNA synthetase
BTI247_RS07070	COG4166	transmembrane transport
BTI247_RS07075	COG0601	transmembrane transport
BTI247_RS07080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTI247_RS07085	COG0444	Belongs to the ABC transporter superfamily
BTI247_RS07090	COG4608	Belongs to the ABC transporter superfamily
BTI247_RS07100	COG4166	transmembrane transport
BTI247_RS07115	COG0861	Integral membrane protein TerC family
BTI247_RS07125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTI247_RS07135	COG1164	Oligoendopeptidase f
BTI247_RS07145	COG2346	COG2346, Truncated hemoglobins
BTI247_RS07150	COG4116	CYTH
BTI247_RS07160	COG2357	RelA SpoT domain protein
BTI247_RS07170	COG0564	pseudouridine synthase activity
BTI247_RS07185	COG0772	Belongs to the SEDS family
BTI247_RS07190	COG1216	Glycosyl transferase, family 2
BTI247_RS07210	COG0463	Glycosyl transferase, family 2
BTI247_RS07210	COG0457	Tetratricopeptide repeat
BTI247_RS07230	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BTI247_RS07245	COG1091	dTDP-4-dehydrorhamnose reductase activity
BTI247_RS07290	COG2153	protein acetylation
BTI247_RS07300	COG2382	esterase
BTI247_RS07320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTI247_RS07330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTI247_RS07330	COG0512	Glutamine amidotransferase of anthranilate synthase
BTI247_RS07365	COG1620	l-lactate permease
BTI247_RS07370	COG5634	Uncharacterized conserved protein (DUF2278)
BTI247_RS07430	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTI247_RS07440	COG1476	TRANSCRIPTIONal
BTI247_RS07475	COG4152	abc transporter atp-binding protein
BTI247_RS07480	COG1668	transmembrane transport
BTI247_RS07535	COG2801	Transposase and inactivated derivatives
BTI247_RS07560	COG2801	Transposase and inactivated derivatives
BTI247_RS07570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTI247_RS07575	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS07610	COG4974	Belongs to the 'phage' integrase family
BTI247_RS07640	COG1686	Belongs to the peptidase S11 family
BTI247_RS07645	COG0681	Belongs to the peptidase S26 family
BTI247_RS07680	COG1012	belongs to the aldehyde dehydrogenase family
BTI247_RS07690	COG1176	ABC-type spermidine putrescine transport system, permease component I
BTI247_RS07695	COG1177	transmembrane transport
BTI247_RS07710	COG2409	Drug exporters of the RND superfamily
BTI247_RS07720	COG0564	pseudouridine synthase activity
BTI247_RS07730	COG2340	Cysteine-rich secretory protein family
BTI247_RS07735	COG0247	lactate metabolic process
BTI247_RS07740	COG2801	Transposase and inactivated derivatives
BTI247_RS07750	COG0247	lactate metabolic process
BTI247_RS07760	COG3835	regulator
BTI247_RS07770	COG0745	RESPONSE REGULATOR receiver
BTI247_RS07775	COG5002	protein histidine kinase activity
BTI247_RS07780	COG2186	Transcriptional regulator
BTI247_RS07800	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BTI247_RS07810	COG2116	formate transmembrane transporter activity
BTI247_RS07815	COG0861	Integral membrane protein TerC family
BTI247_RS07820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTI247_RS07830	COG2030	dehydratase
BTI247_RS07850	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS07855	COG3243	poly(R)-hydroxyalkanoic acid synthase
BTI247_RS07865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTI247_RS07880	COG1840	ABC-type Fe3 transport system, periplasmic component
BTI247_RS07885	COG3842	ATPase activity
BTI247_RS07905	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS07920	COG1349	DNA-binding transcription factor activity
BTI247_RS07935	COG0235	Class ii aldolase
BTI247_RS07945	COG2861	carbohydrate metabolic process
BTI247_RS07955	COG3852	Histidine kinase
BTI247_RS07960	COG1846	Transcriptional regulator
BTI247_RS07970	COG2318	DinB family
BTI247_RS07980	COG5002	protein histidine kinase activity
BTI247_RS07990	COG0720	synthase
BTI247_RS08005	COG4873	Protein conserved in bacteria
BTI247_RS08035	COG1780	Probably involved in ribonucleotide reductase function
BTI247_RS08040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTI247_RS08045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTI247_RS08050	COG1725	Transcriptional regulator
BTI247_RS08055	COG1131	(ABC) transporter
BTI247_RS08065	COG1131	(ABC) transporter
BTI247_RS08085	COG1522	sequence-specific DNA binding
BTI247_RS08095	COG1335	isochorismatase
BTI247_RS08105	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTI247_RS08110	COG2070	2-Nitropropane dioxygenase
BTI247_RS08115	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BTI247_RS08125	COG1696	Membrane protein involved in D-alanine export
BTI247_RS08150	COG0716	FMN binding
BTI247_RS08190	COG1846	Transcriptional regulator
BTI247_RS08200	COG1301	dicarboxylic acid transport
BTI247_RS08205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTI247_RS08210	COG4709	membrane
BTI247_RS08215	COG3874	Sporulation protein YtfJ
BTI247_RS08235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTI247_RS08240	COG0028	Belongs to the TPP enzyme family
BTI247_RS08245	COG0440	acetolactate synthase activity
BTI247_RS08285	COG2801	Transposase and inactivated derivatives
BTI247_RS08330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTI247_RS08345	COG1183	phosphatidylcholine synthase activity
BTI247_RS08350	COG1368	sulfuric ester hydrolase activity
BTI247_RS08360	COG0019	diaminopimelate decarboxylase activity
BTI247_RS08380	COG0529	Catalyzes the synthesis of activated sulfate
BTI247_RS08385	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTI247_RS08405	COG1648	precorrin-2 dehydrogenase activity
BTI247_RS08410	COG0733	neurotransmitter:sodium symporter activity
BTI247_RS08430	COG1757	Na H antiporter
BTI247_RS08445	COG4758	membrane
BTI247_RS08450	COG4585	Histidine kinase
BTI247_RS08455	COG2197	response regulator
BTI247_RS08465	COG1114	Component of the transport system for branched-chain amino acids
BTI247_RS08515	COG0730	response to heat
BTI247_RS08520	COG0306	phosphate transporter
BTI247_RS08525	COG1392	Phosphate transport regulator
BTI247_RS08530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTI247_RS08545	COG3852	Histidine kinase
BTI247_RS08550	COG1801	Protein of unknown function DUF72
BTI247_RS08560	COG0582	viral genome integration into host DNA
BTI247_RS08565	COG5002	protein histidine kinase activity
BTI247_RS08580	COG0392	lysyltransferase activity
BTI247_RS08580	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BTI247_RS08595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTI247_RS08600	COG1686	Belongs to the peptidase S11 family
BTI247_RS08605	COG2715	membrane protein required for spore maturation
BTI247_RS08610	COG0700	Nucleoside recognition
BTI247_RS08615	COG1187	pseudouridine synthase activity
BTI247_RS08625	COG1333	cytochrome c biogenesis protein
BTI247_RS08630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTI247_RS08635	COG0745	RESPONSE REGULATOR receiver
BTI247_RS08640	COG5002	protein histidine kinase activity
BTI247_RS08645	COG2096	Adenosyltransferase
BTI247_RS08660	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BTI247_RS08665	COG1141	Ferredoxin
BTI247_RS08675	COG0514	ATP-dependent DNA helicase (RecQ)
BTI247_RS08680	COG1266	CAAX protease self-immunity
BTI247_RS08690	COG1408	metallophosphoesterase
BTI247_RS08695	COG0789	Transcriptional regulator
BTI247_RS08705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTI247_RS08725	COG0492	ferredoxin-NADP+ reductase activity
BTI247_RS08730	COG0252	asparaginase activity
BTI247_RS08795	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTI247_RS08810	COG0142	geranyltranstransferase activity
BTI247_RS08820	COG0142	geranyltranstransferase activity
BTI247_RS08845	COG0457	Tetratricopeptide repeat
BTI247_RS08865	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTI247_RS08870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTI247_RS08870	COG2010	Cytochrome c
BTI247_RS08875	COG4347	Protein of unknown function (DUF1405)
BTI247_RS08890	COG2738	Putative neutral zinc metallopeptidase
BTI247_RS08900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTI247_RS08905	COG1694	Mazg nucleotide pyrophosphohydrolase
BTI247_RS08925	COG0438	transferase activity, transferring glycosyl groups
BTI247_RS08960	COG1199	ATP-dependent helicase activity
BTI247_RS08960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BTI247_RS08980	COG3935	DnaD domain protein
BTI247_RS08985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTI247_RS08995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTI247_RS08995	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTI247_RS09050	COG0116	Belongs to the methyltransferase superfamily
BTI247_RS09060	COG1199	ATP-dependent helicase activity
BTI247_RS09065	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BTI247_RS09075	COG0024	Methionine aminopeptidase
BTI247_RS09085	COG2233	PERMEase
BTI247_RS09095	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS09100	COG2311	Membrane
BTI247_RS09105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTI247_RS09115	COG0456	acetyltransferase
BTI247_RS09165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTI247_RS09180	COG3944	biosynthesis protein
BTI247_RS09190	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTI247_RS09205	COG1215	transferase activity, transferring glycosyl groups
BTI247_RS09210	COG0438	transferase activity, transferring glycosyl groups
BTI247_RS09230	COG0454	-acetyltransferase
BTI247_RS09250	COG0328	RNA-DNA hybrid ribonuclease activity
BTI247_RS09285	COG3403	YqcI/YcgG family
BTI247_RS09290	COG1280	lysine exporter protein (LysE YggA)
BTI247_RS09310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTI247_RS09315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTI247_RS09325	COG0475	glutathione-regulated potassium exporter activity
BTI247_RS09330	COG0789	Transcriptional regulator
BTI247_RS09330	COG4978	Transcriptional regulator
BTI247_RS09340	COG2323	membrane
BTI247_RS09345	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BTI247_RS09395	COG1923	regulation of RNA biosynthetic process
BTI247_RS09410	COG1360	Flagellar Motor Protein
BTI247_RS09415	COG2201	protein-glutamate methylesterase activity
BTI247_RS09420	COG0643	Histidine kinase
BTI247_RS09420	COG2198	Histidine kinase
BTI247_RS09425	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTI247_RS09425	COG1776	CheC inhibitor of MCP methylation
BTI247_RS09440	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTI247_RS09445	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS09450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTI247_RS09470	COG1256	bacterial-type flagellum assembly
BTI247_RS09475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTI247_RS09495	COG1815	bacterial-type flagellum-dependent cell motility
BTI247_RS09500	COG1558	bacterial-type flagellum-dependent cell motility
BTI247_RS09510	COG1766	The M ring may be actively involved in energy transduction
BTI247_RS09515	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTI247_RS09525	COG1157	protein secretion by the type III secretion system
BTI247_RS09545	COG1749	Flagellar hook protein flgE
BTI247_RS09560	COG0784	Response regulator, receiver
BTI247_RS09560	COG0835	chemotaxis
BTI247_RS09570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTI247_RS09575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTI247_RS09580	COG0741	lytic transglycosylase activity
BTI247_RS09590	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTI247_RS09595	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTI247_RS09595	COG1776	CheC inhibitor of MCP methylation
BTI247_RS09605	COG1338	Plays a role in the flagellum-specific transport system
BTI247_RS09610	COG1987	bacterial-type flagellum assembly
BTI247_RS09620	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTI247_RS09625	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTI247_RS09630	COG1419	protein localization to endoplasmic reticulum
BTI247_RS09645	COG4786	Flagellar basal body rod
BTI247_RS09650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTI247_RS09655	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTI247_RS09685	COG2329	Antibiotic biosynthesis monooxygenase
BTI247_RS09715	COG0583	DNA-binding transcription factor activity
BTI247_RS09720	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS09725	COG3842	ATPase activity
BTI247_RS09775	COG0406	alpha-ribazole phosphatase activity
BTI247_RS09805	COG0367	asparagine synthase
BTI247_RS09835	COG1802	Transcriptional regulator
BTI247_RS09840	COG0697	spore germination
BTI247_RS09850	COG0523	cobalamin synthesis protein
BTI247_RS09855	COG0701	Predicted permease
BTI247_RS09870	COG1757	Na H antiporter
BTI247_RS09875	COG0789	Transcriptional regulator
BTI247_RS09900	COG0534	Mate efflux family protein
BTI247_RS09905	COG3340	Belongs to the peptidase S51 family
BTI247_RS09925	COG0785	Cytochrome C biogenesis protein
BTI247_RS09930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTI247_RS09940	COG0457	Tetratricopeptide repeat
BTI247_RS09960	COG2733	membrane
BTI247_RS09985	COG2197	response regulator
BTI247_RS09995	COG1131	(ABC) transporter
BTI247_RS10015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTI247_RS10020	COG0528	UMP kinase activity
BTI247_RS10030	COG1027	Aspartate ammonia-lyase
BTI247_RS10035	COG0281	malic enzyme
BTI247_RS10040	COG4191	Histidine kinase
BTI247_RS10045	COG0784	Response regulator, receiver
BTI247_RS10050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTI247_RS10105	COG2814	Major facilitator Superfamily
BTI247_RS10125	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS10130	COG1695	Transcriptional regulator
BTI247_RS10140	COG0477	Major facilitator Superfamily
BTI247_RS10155	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTI247_RS10160	COG2223	nitrite transmembrane transporter activity
BTI247_RS10165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTI247_RS10185	COG0733	neurotransmitter:sodium symporter activity
BTI247_RS10195	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS10200	COG5566	PFAM Mor transcription activator
BTI247_RS10205	COG2323	membrane
BTI247_RS10225	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTI247_RS10235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTI247_RS10240	COG0028	Belongs to the TPP enzyme family
BTI247_RS10260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTI247_RS10280	COG2814	Major facilitator Superfamily
BTI247_RS10285	COG3384	dioxygenase
BTI247_RS10295	COG3279	Response regulator of the LytR AlgR family
BTI247_RS10300	COG0427	acetyl-CoA hydrolase
BTI247_RS10320	COG4166	transmembrane transport
BTI247_RS10325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTI247_RS10345	COG1914	H( )-stimulated, divalent metal cation uptake system
BTI247_RS10360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTI247_RS10370	COG0531	amino acid
BTI247_RS10400	COG2309	aminopeptidase activity
BTI247_RS10415	COG0456	acetyltransferase
BTI247_RS10425	COG1266	CAAX protease self-immunity
BTI247_RS10430	COG1309	transcriptional regulator
BTI247_RS10435	COG2390	Transcriptional regulator
BTI247_RS10445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTI247_RS10450	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BTI247_RS10455	COG0295	cytidine deaminase activity
BTI247_RS10460	COG4846	Membrane protein involved in cytochrome C biogenesis
BTI247_RS10480	COG0583	DNA-binding transcription factor activity
BTI247_RS10495	COG0006	proline dipeptidase activity
BTI247_RS10515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTI247_RS10525	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS10540	COG1114	Component of the transport system for branched-chain amino acids
BTI247_RS10550	COG2372	response to copper ion
BTI247_RS10550	COG1276	copper resistance
BTI247_RS10555	COG4549	nuclear export factor GLE1
BTI247_RS10560	COG0697	spore germination
BTI247_RS10565	COG0583	DNA-binding transcription factor activity
BTI247_RS10570	COG1959	2 iron, 2 sulfur cluster binding
BTI247_RS10575	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BTI247_RS10580	COG0778	Nitroreductase
BTI247_RS10600	COG0154	amidase activity
BTI247_RS10605	COG0628	permease
BTI247_RS10615	COG1231	oxidoreductase activity
BTI247_RS10620	COG0523	cobalamin synthesis protein
BTI247_RS10630	COG0411	ABC transporter
BTI247_RS10650	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS10655	COG0583	DNA-binding transcription factor activity
BTI247_RS10665	COG1942	4-Oxalocrotonate Tautomerase
BTI247_RS10685	COG1271	oxidase subunit
BTI247_RS10690	COG1294	oxidase, subunit
BTI247_RS10695	COG4988	ABC transporter
BTI247_RS10700	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BTI247_RS10710	COG1216	Glycosyl transferase, family 2
BTI247_RS10745	COG1686	Belongs to the peptidase S11 family
BTI247_RS10760	COG1388	LysM domain
BTI247_RS10760	COG0791	NLP P60 protein
BTI247_RS10785	COG2801	Transposase and inactivated derivatives
BTI247_RS10800	COG1132	(ABC) transporter
BTI247_RS10805	COG0745	RESPONSE REGULATOR receiver
BTI247_RS10820	COG0300	oxidoreductase activity
BTI247_RS10825	COG4122	O-methyltransferase activity
BTI247_RS10855	COG0460	homoserine dehydrogenase
BTI247_RS10880	COG1316	TRANSCRIPTIONal
BTI247_RS10890	COG0745	RESPONSE REGULATOR receiver
BTI247_RS10895	COG5002	protein histidine kinase activity
BTI247_RS10910	COG1285	pathogenesis
BTI247_RS10935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTI247_RS10945	COG1082	Xylose isomerase domain protein TIM barrel
BTI247_RS10955	COG2814	Major facilitator Superfamily
BTI247_RS10960	COG1279	arginine transmembrane transporter activity
BTI247_RS10965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTI247_RS10975	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTI247_RS11010	COG0577	efflux transmembrane transporter activity
BTI247_RS11015	COG2002	toxin-antitoxin pair type II binding
BTI247_RS11020	COG1404	Belongs to the peptidase S8 family
BTI247_RS11025	COG0640	Transcriptional regulator
BTI247_RS11030	COG0667	Aldo Keto reductase
BTI247_RS11060	COG0840	transmembrane signaling receptor activity
BTI247_RS11075	COG3949	Membrane
BTI247_RS11080	COG0783	Belongs to the Dps family
BTI247_RS11095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTI247_RS11105	COG1231	oxidoreductase activity
BTI247_RS11110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTI247_RS11115	COG4989	oxidoreductase activity
BTI247_RS11125	COG0523	cobalamin synthesis protein
BTI247_RS11130	COG0456	acetyltransferase
BTI247_RS11135	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTI247_RS11140	COG0702	epimerase
BTI247_RS11150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTI247_RS11160	COG4166	transmembrane transport
BTI247_RS11180	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS11190	COG5337	Spore coat protein CotH
BTI247_RS11195	COG1051	belongs to the nudix hydrolase family
BTI247_RS11200	COG0586	Pfam SNARE associated Golgi protein
BTI247_RS11205	COG2244	polysaccharide biosynthetic process
BTI247_RS11215	COG0701	Predicted permease
BTI247_RS11220	COG3689	TIGRFAM TIGR03943 family protein
BTI247_RS11225	COG1607	acyl-coa hydrolase
BTI247_RS11230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTI247_RS11245	COG0702	epimerase
BTI247_RS11250	COG2839	Protein conserved in bacteria
BTI247_RS11255	COG1253	flavin adenine dinucleotide binding
BTI247_RS11280	COG1114	Component of the transport system for branched-chain amino acids
BTI247_RS11285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTI247_RS11300	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTI247_RS11310	COG1876	peptidase activity
BTI247_RS11325	COG2211	Major facilitator Superfamily
BTI247_RS11340	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTI247_RS11350	COG0561	phosphatase activity
BTI247_RS11355	COG1846	Transcriptional regulator
BTI247_RS11360	COG2814	Major facilitator Superfamily
BTI247_RS11370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTI247_RS11375	COG4106	trans-aconitate 2-methyltransferase activity
BTI247_RS11390	COG1819	glycosyl
BTI247_RS11395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTI247_RS11400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTI247_RS11430	COG0456	acetyltransferase
BTI247_RS11455	COG3874	Sporulation protein YtfJ
BTI247_RS11480	COG2226	methyltransferase
BTI247_RS11500	COG1082	Xylose isomerase domain protein TIM barrel
BTI247_RS11505	COG0346	lactoylglutathione lyase activity
BTI247_RS11515	COG0604	alcohol dehydrogenase
BTI247_RS11520	COG1595	DNA-templated transcription, initiation
BTI247_RS11535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTI247_RS11535	COG0426	domain, Protein
BTI247_RS11545	COG0386	Belongs to the glutathione peroxidase family
BTI247_RS11550	COG1305	Transglutaminase-like
BTI247_RS11555	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BTI247_RS11560	COG0714	Associated with various cellular activities
BTI247_RS11565	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BTI247_RS11570	COG1140	nitrate reductase beta subunit
BTI247_RS11575	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BTI247_RS11580	COG2181	nitrate reductase activity
BTI247_RS11585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTI247_RS11590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTI247_RS11600	COG0303	'Molybdopterin
BTI247_RS11605	COG0314	molybdopterin synthase activity
BTI247_RS11615	COG2223	nitrite transmembrane transporter activity
BTI247_RS11630	COG1648	precorrin-2 dehydrogenase activity
BTI247_RS11640	COG1587	Uroporphyrinogen-III synthase
BTI247_RS11640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BTI247_RS11645	COG2146	nitrite reductase [NAD(P)H] activity
BTI247_RS11650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTI247_RS11655	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BTI247_RS11690	COG2359	stage V sporulation protein S
BTI247_RS11710	COG1418	mRNA catabolic process
BTI247_RS11715	COG0488	(ABC) transporter
BTI247_RS11730	COG0629	single-stranded DNA binding
BTI247_RS11740	COG1413	lyase activity
BTI247_RS11755	COG2521	methyltransferase
BTI247_RS11755	COG2136	Putative SAM-dependent methyltransferase
BTI247_RS11760	COG0018	arginyl-trna synthetase
BTI247_RS11800	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BTI247_RS11805	COG0017	Asparaginyl-tRNA synthetase
BTI247_RS11835	COG1674	ftsk spoiiie
BTI247_RS11875	COG0733	neurotransmitter:sodium symporter activity
BTI247_RS11900	COG2610	gluconate transmembrane transporter activity
BTI247_RS11910	COG1794	racemase activity, acting on amino acids and derivatives
BTI247_RS11920	COG0456	acetyltransferase
BTI247_RS11930	COG3655	Transcriptional regulator
BTI247_RS11935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTI247_RS11945	COG1131	(ABC) transporter
BTI247_RS11950	COG4473	ABC transporter
BTI247_RS11960	COG0546	phosphoglycolate phosphatase activity
BTI247_RS11975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTI247_RS11990	COG0768	penicillin binding
BTI247_RS12000	COG0204	Acyl-transferase
BTI247_RS12005	COG1272	protein, Hemolysin III
BTI247_RS12015	COG0805	protein transport
BTI247_RS12025	COG1307	EDD domain protein, DegV family
BTI247_RS12035	COG1999	signal sequence binding
BTI247_RS12040	COG0071	Belongs to the small heat shock protein (HSP20) family
BTI247_RS12045	COG0367	asparagine synthase
BTI247_RS12060	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTI247_RS12065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTI247_RS12070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTI247_RS12075	COG0778	Nitroreductase
BTI247_RS12090	COG1335	isochorismatase
BTI247_RS12100	COG0668	transmembrane transport
BTI247_RS12105	COG4585	Histidine kinase
BTI247_RS12105	COG2203	Gaf domain
BTI247_RS12110	COG2197	response regulator
BTI247_RS12115	COG1737	Transcriptional regulator
BTI247_RS12120	COG0384	phenazine biosynthesis protein PhzF
BTI247_RS12125	COG1064	alcohol dehydrogenase
BTI247_RS12150	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BTI247_RS12185	COG1125	glycine betaine transport
BTI247_RS12185	COG0517	IMP dehydrogenase activity
BTI247_RS12190	COG1174	glycine betaine transport
BTI247_RS12225	COG1253	flavin adenine dinucleotide binding
BTI247_RS12230	COG1012	belongs to the aldehyde dehydrogenase family
BTI247_RS12235	COG5506	Protein of unknown function (DUF1694)
BTI247_RS12250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTI247_RS12255	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BTI247_RS12260	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BTI247_RS12265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTI247_RS12270	COG0456	acetyltransferase
BTI247_RS12275	COG3829	transcription factor binding
BTI247_RS12280	COG1509	lysine 2,3-aminomutase activity
BTI247_RS12315	COG4991	sh3 domain protein
BTI247_RS12315	COG0515	serine threonine protein kinase
BTI247_RS12315	COG3064	Membrane
BTI247_RS12325	COG0671	phosphoesterase, PA-phosphatase related
BTI247_RS12330	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTI247_RS12335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTI247_RS12420	COG0300	oxidoreductase activity
BTI247_RS12450	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTI247_RS12450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTI247_RS12460	COG2814	Major facilitator Superfamily
BTI247_RS12465	COG4841	protein insertion into membrane
BTI247_RS12470	COG0372	Belongs to the citrate synthase family
BTI247_RS12475	COG2079	MmgE PrpD family protein
BTI247_RS12480	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BTI247_RS12485	COG1960	acyl-CoA dehydrogenase activity
BTI247_RS12490	COG2084	Dehydrogenase
BTI247_RS12500	COG1280	lysine exporter protein (LysE YggA)
BTI247_RS12505	COG1024	Enoyl-CoA hydratase
BTI247_RS12515	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS12525	COG0420	3'-5' exonuclease activity
BTI247_RS12530	COG0419	ATPase involved in DNA repair
BTI247_RS12535	COG2801	Transposase and inactivated derivatives
BTI247_RS12560	COG2223	nitrite transmembrane transporter activity
BTI247_RS12565	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS12570	COG1169	isochorismate synthase
BTI247_RS12575	COG1021	2,3-dihydroxybenzoate-AMP ligase
BTI247_RS12580	COG3433	isochorismatase activity
BTI247_RS12580	COG1535	isochorismatase
BTI247_RS12585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BTI247_RS12590	COG3251	PFAM MbtH domain protein
BTI247_RS12595	COG2814	Major facilitator Superfamily
BTI247_RS12610	COG0776	regulation of translation
BTI247_RS12620	COG2318	DinB family
BTI247_RS12630	COG1115	amino acid carrier protein
BTI247_RS12640	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS12655	COG1187	pseudouridine synthase activity
BTI247_RS12660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTI247_RS12665	COG1136	(ABC) transporter
BTI247_RS12675	COG0596	Alpha beta hydrolase
BTI247_RS12685	COG2814	Major facilitator Superfamily
BTI247_RS12685	COG2814	Major facilitator Superfamily
BTI247_RS12700	COG0028	Belongs to the TPP enzyme family
BTI247_RS12735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTI247_RS12750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTI247_RS12785	COG1247	-acetyltransferase
BTI247_RS12810	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BTI247_RS12820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTI247_RS12850	COG0583	DNA-binding transcription factor activity
BTI247_RS12855	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTI247_RS12870	COG0583	DNA-binding transcription factor activity
BTI247_RS12875	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS12880	COG2258	MOSC domain
BTI247_RS12895	COG1132	(ABC) transporter
BTI247_RS12900	COG1132	(ABC) transporter
BTI247_RS12940	COG1396	sequence-specific DNA binding
BTI247_RS12975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTI247_RS12980	COG1595	DNA-templated transcription, initiation
BTI247_RS13005	COG1649	PFAM Uncharacterised BCR, COG1649
BTI247_RS13030	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS13050	COG2801	Transposase and inactivated derivatives
BTI247_RS13065	COG5002	protein histidine kinase activity
BTI247_RS13075	COG2267	carboxylic ester hydrolase activity
BTI247_RS13125	COG2801	Transposase and inactivated derivatives
BTI247_RS13145	COG0768	penicillin binding
BTI247_RS13150	COG1595	DNA-templated transcription, initiation
BTI247_RS13160	COG0768	penicillin binding
BTI247_RS13165	COG0768	penicillin binding
BTI247_RS13175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTI247_RS13180	COG1408	metallophosphoesterase
BTI247_RS13190	COG1131	(ABC) transporter
BTI247_RS13200	COG1309	transcriptional regulator
BTI247_RS13215	COG1960	acyl-CoA dehydrogenase activity
BTI247_RS13220	COG0439	Biotin carboxylase
BTI247_RS13225	COG0511	ligase activity, forming carbon-carbon bonds
BTI247_RS13230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTI247_RS13235	COG1024	Enoyl-CoA hydratase
BTI247_RS13240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BTI247_RS13245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTI247_RS13265	COG0572	uridine kinase
BTI247_RS13285	COG1686	Belongs to the peptidase S11 family
BTI247_RS13315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTI247_RS13330	COG3227	Zinc metalloprotease (Elastase)
BTI247_RS13335	COG2207	Transcriptional regulator
BTI247_RS13355	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS13365	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS13410	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS13415	COG1733	regulation of RNA biosynthetic process
BTI247_RS13420	COG2226	methyltransferase
BTI247_RS13430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTI247_RS13475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTI247_RS13490	COG1063	alcohol dehydrogenase
BTI247_RS13500	COG2323	membrane
BTI247_RS13515	COG3386	PFAM SMP-30 Gluconolaconase
BTI247_RS13525	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BTI247_RS13530	COG3773	Cell wall hydrolase
BTI247_RS13540	COG0745	RESPONSE REGULATOR receiver
BTI247_RS13545	COG2205	protein histidine kinase activity
BTI247_RS13555	COG0488	(ABC) transporter
BTI247_RS13570	COG1136	(ABC) transporter
BTI247_RS13575	COG0577	efflux transmembrane transporter activity
BTI247_RS13600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTI247_RS13610	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BTI247_RS13635	COG0582	viral genome integration into host DNA
BTI247_RS13720	COG0582	viral genome integration into host DNA
BTI247_RS13755	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS13850	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS13895	COG2124	cytochrome p450
BTI247_RS13930	COG0561	phosphatase activity
BTI247_RS13935	COG5002	protein histidine kinase activity
BTI247_RS13940	COG0768	penicillin binding
BTI247_RS13950	COG1819	glycosyl
BTI247_RS13975	COG2205	protein histidine kinase activity
BTI247_RS14015	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS14030	COG0076	glutamate decarboxylase activity
BTI247_RS14035	COG0657	acetylesterase activity
BTI247_RS14040	COG1073	alpha beta
BTI247_RS14045	COG0577	efflux transmembrane transporter activity
BTI247_RS14050	COG1136	(ABC) transporter
BTI247_RS14065	COG5002	protein histidine kinase activity
BTI247_RS14070	COG0745	RESPONSE REGULATOR receiver
BTI247_RS14075	COG1011	Hydrolase
BTI247_RS14105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTI247_RS14115	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS14150	COG0322	excinuclease ABC activity
BTI247_RS14185	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS14220	COG3878	Protein conserved in bacteria
BTI247_RS14245	COG2816	NAD+ diphosphatase activity
BTI247_RS14265	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS14270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTI247_RS14305	COG0697	spore germination
BTI247_RS14310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTI247_RS14330	COG0584	glycerophosphoryl diester phosphodiesterase
BTI247_RS14350	COG0789	Transcriptional regulator
BTI247_RS14350	COG4978	Transcriptional regulator
BTI247_RS14355	COG2814	Major facilitator Superfamily
BTI247_RS14375	COG2801	Transposase and inactivated derivatives
BTI247_RS14430	COG0768	penicillin binding
BTI247_RS14435	COG0671	phosphoesterase, PA-phosphatase related
BTI247_RS14440	COG0604	alcohol dehydrogenase
BTI247_RS14445	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTI247_RS14470	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS14480	COG1523	belongs to the glycosyl hydrolase 13 family
BTI247_RS14485	COG3227	Zinc metalloprotease (Elastase)
BTI247_RS14490	COG0737	Belongs to the 5'-nucleotidase family
BTI247_RS14505	COG0201	protein transport
BTI247_RS14510	COG0697	spore germination
BTI247_RS14515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTI247_RS14540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTI247_RS14570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTI247_RS14585	COG2959	enzyme of heme biosynthesis
BTI247_RS14625	COG1309	transcriptional regulator
BTI247_RS14650	COG3284	Transcriptional regulator
BTI247_RS14665	COG1349	DNA-binding transcription factor activity
BTI247_RS14680	COG1959	2 iron, 2 sulfur cluster binding
BTI247_RS14695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTI247_RS14700	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTI247_RS14705	COG0022	dehydrogenase e1 component
BTI247_RS14710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTI247_RS14720	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS14725	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTI247_RS14725	COG0456	acetyltransferase
BTI247_RS14765	COG4176	ABC-type proline glycine betaine transport system permease component
BTI247_RS14770	COG0517	IMP dehydrogenase activity
BTI247_RS14770	COG4175	Glycine betaine
BTI247_RS14800	COG2153	protein acetylation
BTI247_RS14810	COG1819	glycosyl
BTI247_RS14835	COG2315	Protein conserved in bacteria
BTI247_RS14845	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS14890	COG2801	Transposase and inactivated derivatives
BTI247_RS14895	COG3973	AAA domain
BTI247_RS14915	COG0514	ATP-dependent DNA helicase (RecQ)
BTI247_RS14945	COG4637	Psort location Cytoplasmic, score
BTI247_RS14965	COG3397	chitin binding
BTI247_RS14980	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTI247_RS14985	COG1115	amino acid carrier protein
BTI247_RS14990	COG1012	belongs to the aldehyde dehydrogenase family
BTI247_RS14995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTI247_RS15005	COG3938	Belongs to the proline racemase family
BTI247_RS15010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTI247_RS15055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTI247_RS15060	COG1078	dGTPase activity
BTI247_RS15065	COG0586	Pfam SNARE associated Golgi protein
BTI247_RS15075	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BTI247_RS15085	COG4166	transmembrane transport
BTI247_RS15095	COG4948	Mandelate Racemase Muconate Lactonizing
BTI247_RS15110	COG0667	Aldo Keto reductase
BTI247_RS15150	COG5002	protein histidine kinase activity
BTI247_RS15150	COG3850	Histidine kinase
BTI247_RS15155	COG0745	RESPONSE REGULATOR receiver
BTI247_RS15190	COG1164	Oligoendopeptidase f
BTI247_RS15195	COG1307	EDD domain protein, DegV family
BTI247_RS15235	COG2814	Major facilitator Superfamily
BTI247_RS15245	COG1664	Polymer-forming cytoskeletal
BTI247_RS15250	COG0789	Transcriptional regulator
BTI247_RS15255	COG4533	DNA binding
BTI247_RS15260	COG2814	Major facilitator Superfamily
BTI247_RS15260	COG0477	Major facilitator Superfamily
BTI247_RS15285	COG2261	transglycosylase associated protein
BTI247_RS15300	COG2226	methyltransferase
BTI247_RS15335	COG0436	Aminotransferase
BTI247_RS15340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTI247_RS15350	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BTI247_RS15385	COG0628	permease
BTI247_RS15395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTI247_RS15400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTI247_RS15405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTI247_RS15445	COG2746	aminoglycoside 3-N-acetyltransferase activity
BTI247_RS15455	COG0697	spore germination
BTI247_RS15465	COG2318	DinB family
BTI247_RS15485	COG4912	Dna alkylation repair
BTI247_RS15495	COG0346	lactoylglutathione lyase activity
BTI247_RS15500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTI247_RS15515	COG0861	Integral membrane protein TerC family
BTI247_RS15520	COG1368	sulfuric ester hydrolase activity
BTI247_RS15525	COG0488	(ABC) transporter
BTI247_RS15530	COG2409	Drug exporters of the RND superfamily
BTI247_RS15530	COG1033	growth of symbiont in host cell
BTI247_RS15535	COG1309	transcriptional regulator
BTI247_RS15540	COG1051	belongs to the nudix hydrolase family
BTI247_RS15555	COG0287	Prephenate dehydrogenase
BTI247_RS15570	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTI247_RS15570	COG1605	Chorismate mutase
BTI247_RS15625	COG0277	FAD linked oxidase domain protein
BTI247_RS15635	COG1595	DNA-templated transcription, initiation
BTI247_RS15655	COG1879	ABC-type sugar transport system periplasmic component
BTI247_RS15660	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTI247_RS15665	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTI247_RS15675	COG2390	Transcriptional regulator
BTI247_RS15680	COG1070	Carbohydrate kinase
BTI247_RS15705	COG2329	Antibiotic biosynthesis monooxygenase
BTI247_RS15710	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS15720	COG0640	Transcriptional regulator
BTI247_RS15725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTI247_RS15740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTI247_RS15745	COG4187	Peptidase family M20/M25/M40
BTI247_RS15750	COG1414	Transcriptional regulator
BTI247_RS15755	COG0833	amino acid
BTI247_RS15770	COG3239	Fatty acid desaturase
BTI247_RS15780	COG2720	vancomycin resistance protein
BTI247_RS15785	COG1785	Belongs to the alkaline phosphatase family
BTI247_RS15795	COG3655	Transcriptional regulator
BTI247_RS15820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTI247_RS15825	COG0346	lactoylglutathione lyase activity
BTI247_RS15850	COG0714	Associated with various cellular activities
BTI247_RS15870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTI247_RS15875	COG0753	catalase activity
BTI247_RS15910	COG0778	Nitroreductase
BTI247_RS15915	COG1846	Transcriptional regulator
BTI247_RS15960	COG1725	Transcriptional regulator
BTI247_RS15980	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS15995	COG0456	acetyltransferase
BTI247_RS16010	COG0697	spore germination
BTI247_RS16015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTI247_RS16030	COG0642	Histidine kinase
BTI247_RS16035	COG0745	RESPONSE REGULATOR receiver
BTI247_RS16040	COG0596	Alpha beta hydrolase
BTI247_RS16075	COG0730	response to heat
BTI247_RS16085	COG0833	amino acid
BTI247_RS16095	COG4335	DNA alkylation repair
BTI247_RS16105	COG5002	protein histidine kinase activity
BTI247_RS16110	COG0745	RESPONSE REGULATOR receiver
BTI247_RS16120	COG0577	efflux transmembrane transporter activity
BTI247_RS16120	COG1136	(ABC) transporter
BTI247_RS16155	COG0768	penicillin binding
BTI247_RS16185	COG1984	allophanate hydrolase subunit 2
BTI247_RS16190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BTI247_RS16195	COG1414	Transcriptional regulator
BTI247_RS16210	COG3142	Participates in the control of copper homeostasis
BTI247_RS16215	COG0640	Transcriptional regulator
BTI247_RS16225	COG1960	acyl-CoA dehydrogenase activity
BTI247_RS16235	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS16245	COG3314	Sporulation integral membrane protein YlbJ
BTI247_RS16265	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BTI247_RS16290	COG3848	Pyruvate phosphate dikinase
BTI247_RS16290	COG0574	Belongs to the PEP-utilizing enzyme family
BTI247_RS16295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTI247_RS16315	COG1063	alcohol dehydrogenase
BTI247_RS16325	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTI247_RS16335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BTI247_RS16350	COG0737	Belongs to the 5'-nucleotidase family
BTI247_RS16355	COG2267	carboxylic ester hydrolase activity
BTI247_RS16360	COG1335	isochorismatase
BTI247_RS16380	COG0583	DNA-binding transcription factor activity
BTI247_RS16385	COG1846	Transcriptional regulator
BTI247_RS16390	COG0598	Magnesium transport protein CorA
BTI247_RS16425	COG0814	amino acid
BTI247_RS16430	COG0697	spore germination
BTI247_RS16450	COG0415	Belongs to the DNA photolyase family
BTI247_RS16455	COG0288	reversible hydration of carbon dioxide
BTI247_RS16465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTI247_RS16470	COG5609	conserved protein (DUF2294)
BTI247_RS16480	COG0456	acetyltransferase
BTI247_RS16485	COG1575	Belongs to the MenA family. Type 1 subfamily
BTI247_RS16495	COG0798	PFAM Bile acid sodium symporter
BTI247_RS16500	COG0346	lactoylglutathione lyase activity
BTI247_RS16505	COG0640	Transcriptional regulator
BTI247_RS16520	COG2801	Transposase and inactivated derivatives
BTI247_RS16525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTI247_RS16525	COG3320	Male sterility
BTI247_RS16530	COG1309	transcriptional regulator
BTI247_RS16540	COG1309	transcriptional regulator
BTI247_RS16575	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS16580	COG1522	sequence-specific DNA binding
BTI247_RS16595	COG0346	lactoylglutathione lyase activity
BTI247_RS16640	COG1253	flavin adenine dinucleotide binding
BTI247_RS16670	COG0814	amino acid
BTI247_RS16675	COG0583	DNA-binding transcription factor activity
BTI247_RS16715	COG0745	RESPONSE REGULATOR receiver
BTI247_RS16720	COG5002	protein histidine kinase activity
BTI247_RS16720	COG3850	Histidine kinase
BTI247_RS16770	COG1136	(ABC) transporter
BTI247_RS16805	COG2814	Major facilitator Superfamily
BTI247_RS16825	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS16835	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BTI247_RS16845	COG1690	Belongs to the RtcB family
BTI247_RS16855	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BTI247_RS16875	COG0577	efflux transmembrane transporter activity
BTI247_RS16895	COG3850	Histidine kinase
BTI247_RS16895	COG5002	protein histidine kinase activity
BTI247_RS16905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTI247_RS16925	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTI247_RS16945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTI247_RS16965	COG0662	Cupin 2, conserved barrel domain protein
BTI247_RS16970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTI247_RS16970	COG2207	Transcriptional regulator
BTI247_RS16990	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTI247_RS16990	COG3409	Peptidoglycan-binding domain 1 protein
BTI247_RS17010	COG1876	peptidase activity
BTI247_RS17015	COG2843	Capsule synthesis protein
BTI247_RS17025	COG0477	Major facilitator Superfamily
BTI247_RS17040	COG1846	Transcriptional regulator
BTI247_RS17045	COG2814	Major facilitator Superfamily
BTI247_RS17055	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BTI247_RS17060	COG1131	(ABC) transporter
BTI247_RS17090	COG2031	fatty acid transporter
BTI247_RS17100	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTI247_RS17155	COG1288	antiporter activity
BTI247_RS17160	COG2356	endonuclease I
BTI247_RS17170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTI247_RS17195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BTI247_RS17215	COG1733	regulation of RNA biosynthetic process
BTI247_RS17220	COG0778	Nitroreductase
BTI247_RS17230	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS17255	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS17265	COG1131	(ABC) transporter
BTI247_RS17290	COG1011	Hydrolase
BTI247_RS17300	COG2365	Tyrosine phosphatase family
BTI247_RS17325	COG0346	lactoylglutathione lyase activity
BTI247_RS17330	COG1940	carbohydrate kinase activity
BTI247_RS17340	COG0110	maltose O-acetyltransferase activity
BTI247_RS17355	COG0628	permease
BTI247_RS17390	COG0477	Major facilitator Superfamily
BTI247_RS17415	COG1253	flavin adenine dinucleotide binding
BTI247_RS17420	COG0789	Transcriptional regulator
BTI247_RS17430	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTI247_RS17455	COG0697	spore germination
BTI247_RS17465	COG1357	PFAM Pentapeptide repeats (8 copies)
BTI247_RS17470	COG3813	Protein conserved in bacteria
BTI247_RS17475	COG2706	6-phosphogluconolactonase activity
BTI247_RS17480	COG1070	Carbohydrate kinase
BTI247_RS17495	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BTI247_RS17500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BTI247_RS17505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTI247_RS17510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTI247_RS17515	COG0604	alcohol dehydrogenase
BTI247_RS17520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTI247_RS17530	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS17545	COG0840	transmembrane signaling receptor activity
BTI247_RS17555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTI247_RS17555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTI247_RS17560	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTI247_RS17565	COG1733	regulation of RNA biosynthetic process
BTI247_RS17580	COG0656	L-ascorbic acid biosynthetic process
BTI247_RS17585	COG2814	Major facilitator Superfamily
BTI247_RS17605	COG0814	amino acid
BTI247_RS17640	COG1733	regulation of RNA biosynthetic process
BTI247_RS17645	COG2188	Transcriptional regulator
BTI247_RS17650	COG0673	inositol 2-dehydrogenase activity
BTI247_RS17655	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BTI247_RS17660	COG1733	regulation of RNA biosynthetic process
BTI247_RS17665	COG1733	regulation of RNA biosynthetic process
BTI247_RS17690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTI247_RS17695	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS17715	COG0384	phenazine biosynthesis protein PhzF
BTI247_RS17720	COG0318	PFAM AMP-dependent synthetase and ligase
BTI247_RS17725	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTI247_RS17730	COG1733	regulation of RNA biosynthetic process
BTI247_RS17740	COG0726	polysaccharide deacetylase
BTI247_RS17760	COG1280	lysine exporter protein (LysE YggA)
BTI247_RS17815	COG1151	hydroxylamine reductase activity
BTI247_RS17855	COG2072	flavoprotein involved in K transport
BTI247_RS17890	COG1113	amino acid transport
BTI247_RS17895	COG2814	Major facilitator Superfamily
BTI247_RS17925	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BTI247_RS17930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTI247_RS17945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTI247_RS17950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTI247_RS17955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTI247_RS17960	COG3739	integral membrane protein
BTI247_RS17975	COG3739	integral membrane protein
BTI247_RS18005	COG0583	DNA-binding transcription factor activity
BTI247_RS18035	COG2801	Transposase and inactivated derivatives
BTI247_RS18040	COG1193	negative regulation of DNA recombination
BTI247_RS18055	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BTI247_RS18060	COG1164	Oligoendopeptidase f
BTI247_RS18080	COG3781	membrane
BTI247_RS18095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTI247_RS18120	COG0584	glycerophosphoryl diester phosphodiesterase
BTI247_RS18130	COG3973	AAA domain
BTI247_RS18165	COG0640	Transcriptional regulator
BTI247_RS18170	COG0604	alcohol dehydrogenase
BTI247_RS18180	COG0457	Tetratricopeptide repeat
BTI247_RS18190	COG2808	Putative FMN-binding domain
BTI247_RS18205	COG0277	FAD linked oxidase domain protein
BTI247_RS18230	COG0823	Involved in the tonB-independent uptake of proteins
BTI247_RS18235	COG3397	chitin binding
BTI247_RS18255	COG0697	spore germination
BTI247_RS18295	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS18315	COG5001	Diguanylate cyclase
BTI247_RS18315	COG3300	MHYT domain
BTI247_RS18320	COG2801	Transposase and inactivated derivatives
BTI247_RS18340	COG1309	transcriptional regulator
BTI247_RS18365	COG1876	peptidase activity
BTI247_RS18390	COG3852	Histidine kinase
BTI247_RS18400	COG1285	pathogenesis
BTI247_RS18410	COG2514	catechol 2,3-dioxygenase activity
BTI247_RS18415	COG2720	vancomycin resistance protein
BTI247_RS18435	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS18455	COG0716	FMN binding
BTI247_RS18465	COG1051	belongs to the nudix hydrolase family
BTI247_RS18485	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS18495	COG0165	Argininosuccinate lyase
BTI247_RS18510	COG4145	pantothenate transmembrane transporter activity
BTI247_RS18520	COG1012	belongs to the aldehyde dehydrogenase family
BTI247_RS18525	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS18535	COG1657	PFAM Prenyltransferase squalene oxidase
BTI247_RS18540	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BTI247_RS18545	COG2962	Rard protein
BTI247_RS18550	COG3326	Membrane
BTI247_RS18565	COG0489	protein tyrosine kinase activity
BTI247_RS18575	COG0314	molybdopterin synthase activity
BTI247_RS18580	COG0303	'Molybdopterin
BTI247_RS18585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTI247_RS18590	COG2116	formate transmembrane transporter activity
BTI247_RS18600	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTI247_RS18605	COG5609	conserved protein (DUF2294)
BTI247_RS18610	COG2427	Protein of unknown function (DUF1641)
BTI247_RS18615	COG3383	formate dehydrogenase (NAD+) activity
BTI247_RS18620	COG0697	spore germination
BTI247_RS18670	COG2226	methyltransferase
BTI247_RS18675	COG4166	transmembrane transport
BTI247_RS18680	COG4166	transmembrane transport
BTI247_RS18685	COG4166	transmembrane transport
BTI247_RS18690	COG1316	TRANSCRIPTIONal
BTI247_RS18700	COG1595	DNA-templated transcription, initiation
BTI247_RS18710	COG1131	(ABC) transporter
BTI247_RS18740	COG0673	inositol 2-dehydrogenase activity
BTI247_RS18745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTI247_RS18750	COG0187	DNA topoisomerase II activity
BTI247_RS18755	COG1832	CoA-binding protein
BTI247_RS18760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTI247_RS18765	COG0745	RESPONSE REGULATOR receiver
BTI247_RS18775	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BTI247_RS18775	COG1328	CTP reductase activity
BTI247_RS18785	COG4841	protein insertion into membrane
BTI247_RS18790	COG0824	Thioesterase
BTI247_RS18815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTI247_RS18825	COG2274	protein secretion by the type I secretion system
BTI247_RS18830	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTI247_RS18860	COG2211	Major facilitator Superfamily
BTI247_RS18870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTI247_RS18885	COG0183	Belongs to the thiolase family
BTI247_RS18890	COG0318	PFAM AMP-dependent synthetase and ligase
BTI247_RS18895	COG1268	BioY protein
BTI247_RS18900	COG0318	PFAM AMP-dependent synthetase and ligase
BTI247_RS18905	COG1396	sequence-specific DNA binding
BTI247_RS18940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTI247_RS18950	COG5002	protein histidine kinase activity
BTI247_RS18955	COG0400	carboxylic ester hydrolase activity
BTI247_RS18960	COG0346	lactoylglutathione lyase activity
BTI247_RS18965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTI247_RS18975	COG0069	glutamate synthase activity
BTI247_RS18980	COG1902	pentaerythritol trinitrate reductase activity
BTI247_RS18985	COG1329	Transcriptional regulator
BTI247_RS18990	COG0010	Belongs to the arginase family
BTI247_RS19015	COG2226	methyltransferase
BTI247_RS19040	COG4846	Membrane protein involved in cytochrome C biogenesis
BTI247_RS19045	COG0785	Cytochrome C biogenesis protein
BTI247_RS19055	COG1473	amidohydrolase
BTI247_RS19080	COG0583	DNA-binding transcription factor activity
BTI247_RS19090	COG1346	cytolysis
BTI247_RS19105	COG0730	response to heat
BTI247_RS19115	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS19135	COG1132	(ABC) transporter
BTI247_RS19140	COG1132	(ABC) transporter
BTI247_RS19175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTI247_RS19180	COG0737	Belongs to the 5'-nucleotidase family
BTI247_RS19190	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTI247_RS19210	COG1695	Transcriptional regulator
BTI247_RS19215	COG0174	glutamine synthetase
BTI247_RS19220	COG0789	Transcriptional regulator
BTI247_RS19225	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BTI247_RS19230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTI247_RS19235	COG2860	membrane
BTI247_RS19245	COG0464	growth
BTI247_RS19275	COG3584	3D domain protein
BTI247_RS19275	COG1388	LysM domain
BTI247_RS19280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTI247_RS19280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTI247_RS19280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTI247_RS19285	COG1105	Belongs to the carbohydrate kinase PfkB family
BTI247_RS19290	COG1349	DNA-binding transcription factor activity
BTI247_RS19295	COG1979	alcohol dehydrogenase
BTI247_RS19300	COG2322	membrane
BTI247_RS19315	COG1113	amino acid transport
BTI247_RS19325	COG1408	metallophosphoesterase
BTI247_RS19330	COG2116	formate transmembrane transporter activity
BTI247_RS19345	COG2217	Heavy metal translocating P-type atpase
BTI247_RS19350	COG2608	mercury ion transmembrane transporter activity
BTI247_RS19355	COG1937	Protein conserved in bacteria
BTI247_RS19375	COG2819	hydrolase of the alpha beta superfamily
BTI247_RS19380	COG1120	ATPase activity
BTI247_RS19385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTI247_RS19390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTI247_RS19395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTI247_RS19400	COG0708	Exodeoxyribonuclease III
BTI247_RS19405	COG2169	Transcriptional regulator
BTI247_RS19410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTI247_RS19415	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BTI247_RS19425	COG2364	Membrane
BTI247_RS19440	COG2267	carboxylic ester hydrolase activity
BTI247_RS19445	COG3300	MHYT domain
BTI247_RS19445	COG5001	Diguanylate cyclase
BTI247_RS19465	COG1086	Polysaccharide biosynthesis protein
BTI247_RS19480	COG1346	cytolysis
BTI247_RS19495	COG2801	Transposase and inactivated derivatives
BTI247_RS19500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTI247_RS19510	COG2188	Transcriptional regulator
BTI247_RS19515	COG2723	6-phospho-beta-galactosidase activity
BTI247_RS19525	COG1404	Belongs to the peptidase S8 family
BTI247_RS19530	COG3773	Cell wall hydrolase
BTI247_RS19540	COG1368	sulfuric ester hydrolase activity
BTI247_RS19545	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTI247_RS19580	COG4550	Control of competence regulator ComK, YlbF/YmcA
BTI247_RS19590	COG1013	pyruvate-flavodoxin oxidoreductase activity
BTI247_RS19595	COG0674	pyruvate-flavodoxin oxidoreductase activity
BTI247_RS19595	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BTI247_RS19605	COG2359	stage V sporulation protein S
BTI247_RS19610	COG1692	metallophosphoesterase
BTI247_RS19640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTI247_RS19645	COG1426	Protein conserved in bacteria
BTI247_RS19660	COG0300	oxidoreductase activity
BTI247_RS19665	COG0612	Peptidase, M16
BTI247_RS19670	COG0612	Peptidase, M16
BTI247_RS19675	COG1079	Belongs to the binding-protein-dependent transport system permease family
BTI247_RS19680	COG4603	Belongs to the binding-protein-dependent transport system permease family
BTI247_RS19685	COG3845	ABC transporter
BTI247_RS19690	COG1744	ABC transporter substrate-binding protein PnrA-like
BTI247_RS19695	COG2188	Transcriptional regulator
BTI247_RS19715	COG0740	serine-type endopeptidase activity
BTI247_RS19720	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTI247_RS19730	COG0527	aspartate kinase activity
BTI247_RS19735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTI247_RS19740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTI247_RS19745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTI247_RS19750	COG1873	PFAM PRC-barrel domain
BTI247_RS19755	COG0612	Peptidase, M16
BTI247_RS19760	COG0726	polysaccharide deacetylase
BTI247_RS19775	COG0196	riboflavin kinase activity
BTI247_RS19785	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BTI247_RS19790	COG1550	Protein conserved in bacteria
BTI247_RS19800	COG1358	cellular component organization or biogenesis
BTI247_RS19805	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BTI247_RS19810	COG0195	Participates in both transcription termination and antitermination
BTI247_RS19830	COG0750	zinc metalloprotease
BTI247_RS19840	COG4589	Belongs to the CDS family
BTI247_RS19885	COG4974	Belongs to the 'phage' integrase family
BTI247_RS19895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTI247_RS19900	COG0758	DNA mediated transformation
BTI247_RS19905	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BTI247_RS19945	COG1837	Belongs to the UPF0109 family
BTI247_RS19955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTI247_RS19965	COG0552	protein localization to endoplasmic reticulum
BTI247_RS19970	COG1196	nuclear chromosome segregation
BTI247_RS19980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTI247_RS19985	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS19990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BTI247_RS20005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BTI247_RS20010	COG1461	Dihydroxyacetone kinase
BTI247_RS20015	COG1302	Protein conserved in bacteria
BTI247_RS20030	COG1564	THIamine pyrophosphokinase
BTI247_RS20035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BTI247_RS20045	COG2815	serine threonine protein kinase
BTI247_RS20045	COG0515	serine threonine protein kinase
BTI247_RS20050	COG0631	protein serine/threonine phosphatase activity
BTI247_RS20060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTI247_RS20060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTI247_RS20075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BTI247_RS20080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTI247_RS20100	COG1561	YicC-like family, N-terminal region
BTI247_RS20105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BTI247_RS20120	COG0006	proline dipeptidase activity
BTI247_RS20140	COG3069	C4-dicarboxylate transmembrane transporter activity
BTI247_RS20200	COG0564	pseudouridine synthase activity
BTI247_RS20220	COG3599	regulation of cell shape
BTI247_RS20225	COG2302	S4 RNA-binding domain
BTI247_RS20230	COG0762	integral membrane protein
BTI247_RS20240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BTI247_RS20250	COG1873	PFAM PRC-barrel domain
BTI247_RS20255	COG1191	sigma factor activity
BTI247_RS20260	COG1191	sigma factor activity
BTI247_RS20270	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BTI247_RS20275	COG0849	cell division
BTI247_RS20295	COG0772	Belongs to the SEDS family
BTI247_RS20315	COG0768	penicillin binding
BTI247_RS20320	COG0768	penicillin binding
BTI247_RS20340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTI247_RS20355	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BTI247_RS20360	COG1399	metal-binding, possibly nucleic acid-binding protein
BTI247_RS20370	COG3480	Lon protease (S16) C-terminal proteolytic domain
BTI247_RS20375	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTI247_RS20380	COG3314	Sporulation integral membrane protein YlbJ
BTI247_RS20390	COG0742	ribosomal rna small subunit methyltransferase
BTI247_RS20405	COG3679	Belongs to the UPF0342 family
BTI247_RS20410	COG0406	alpha-ribazole phosphatase activity
BTI247_RS20425	COG2340	Cysteine-rich secretory protein family
BTI247_RS20440	COG3336	cytochrome c oxidase
BTI247_RS20475	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BTI247_RS20480	COG0772	Belongs to the SEDS family
BTI247_RS20490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BTI247_RS20495	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BTI247_RS20505	COG4896	Protein conserved in bacteria
BTI247_RS20520	COG1217	gtp-binding protein TYPA
BTI247_RS20530	COG0483	inositol monophosphate 1-phosphatase activity
BTI247_RS20550	COG1982	Orn Lys Arg decarboxylase major
BTI247_RS20600	COG0022	dehydrogenase e1 component
BTI247_RS20605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTI247_RS20620	COG0561	phosphatase activity
BTI247_RS20630	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTI247_RS20635	COG0569	domain protein
BTI247_RS20655	COG0583	DNA-binding transcription factor activity
BTI247_RS20660	COG0517	IMP dehydrogenase activity
BTI247_RS20670	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BTI247_RS20680	COG4703	Protein of unknown function (DUF1797)
BTI247_RS20695	COG2200	EAL domain
BTI247_RS20700	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS20705	COG1408	metallophosphoesterase
BTI247_RS20750	COG2814	Major facilitator Superfamily
BTI247_RS20770	COG3209	COG3209 Rhs family protein
BTI247_RS20780	COG2205	protein histidine kinase activity
BTI247_RS20790	COG0436	Aminotransferase
BTI247_RS20795	COG1609	Transcriptional regulator
BTI247_RS20800	COG3833	ABC-type maltose transport systems, permease component
BTI247_RS20805	COG1175	transmembrane transport
BTI247_RS20810	COG2182	Extracellular solute-binding protein
BTI247_RS20820	COG0366	Alpha amylase catalytic
BTI247_RS20825	COG3842	ATPase activity
BTI247_RS20865	COG0183	Belongs to the thiolase family
BTI247_RS20895	COG1695	Transcriptional regulator
BTI247_RS20900	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS20920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTI247_RS20925	COG0436	Aminotransferase
BTI247_RS20960	COG2084	Dehydrogenase
BTI247_RS20970	COG2199	diguanylate cyclase activity
BTI247_RS20975	COG0778	Nitroreductase
BTI247_RS21000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTI247_RS21000	COG1263	PTS System
BTI247_RS21000	COG2190	(PTS) system
BTI247_RS21005	COG3711	transcriptional antiterminator
BTI247_RS21015	COG2188	Transcriptional regulator
BTI247_RS21025	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BTI247_RS21050	COG1547	Domain of unknown function (DUF309)
BTI247_RS21055	COG0456	acetyltransferase
BTI247_RS21060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTI247_RS21065	COG4086	secreted protein
BTI247_RS21070	COG0561	phosphatase activity
BTI247_RS21075	COG0697	spore germination
BTI247_RS21090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTI247_RS21115	COG0733	neurotransmitter:sodium symporter activity
BTI247_RS21135	COG1686	Belongs to the peptidase S11 family
BTI247_RS21140	COG1725	Transcriptional regulator
BTI247_RS21145	COG1131	(ABC) transporter
BTI247_RS21165	COG1846	Transcriptional regulator
BTI247_RS21180	COG0598	Magnesium transport protein CorA
BTI247_RS21215	COG4974	Belongs to the 'phage' integrase family
BTI247_RS21225	COG0735	belongs to the Fur family
BTI247_RS21230	COG1300	Membrane
BTI247_RS21250	COG0667	Aldo Keto reductase
BTI247_RS21255	COG0656	L-ascorbic acid biosynthetic process
BTI247_RS21260	COG0456	acetyltransferase
BTI247_RS21260	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTI247_RS21270	COG0737	Belongs to the 5'-nucleotidase family
BTI247_RS21270	COG1525	nuclease
BTI247_RS21270	COG4085	toxin activity
BTI247_RS21280	COG0596	Alpha beta hydrolase
BTI247_RS21285	COG2056	Na+-H+ antiporter family
BTI247_RS21290	COG1609	Transcriptional regulator
BTI247_RS21295	COG0456	acetyltransferase
BTI247_RS21300	COG1073	alpha beta
BTI247_RS21315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTI247_RS21315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTI247_RS21320	COG0307	riboflavin synthase, alpha
BTI247_RS21350	COG1073	alpha beta
BTI247_RS21350	COG2226	methyltransferase
BTI247_RS21365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTI247_RS21375	COG1757	Na H antiporter
BTI247_RS21380	COG0737	Belongs to the 5'-nucleotidase family
BTI247_RS21390	COG1522	sequence-specific DNA binding
BTI247_RS21435	COG0300	oxidoreductase activity
BTI247_RS21440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTI247_RS21445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTI247_RS21450	COG1760	l-serine dehydratase
BTI247_RS21455	COG1760	l-serine dehydratase
BTI247_RS21480	COG1285	pathogenesis
BTI247_RS21490	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTI247_RS21495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTI247_RS21505	COG1376	ErfK ybiS ycfS ynhG family protein
BTI247_RS21510	COG4129	membrane
BTI247_RS21515	COG1126	abc transporter atp-binding protein
BTI247_RS21520	COG0765	amino acid transport
BTI247_RS21525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTI247_RS21545	COG2323	membrane
BTI247_RS21550	COG0772	Belongs to the SEDS family
BTI247_RS21555	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTI247_RS21560	COG0022	dehydrogenase e1 component
BTI247_RS21565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTI247_RS21570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTI247_RS21585	COG0280	phosphate acetyltransferase
BTI247_RS21590	COG3290	protein histidine kinase activity
BTI247_RS21590	COG3829	transcription factor binding
BTI247_RS21600	COG0584	glycerophosphoryl diester phosphodiesterase
BTI247_RS21605	COG3093	addiction module antidote protein HigA
BTI247_RS21620	COG0750	zinc metalloprotease
BTI247_RS21625	COG0497	DNA recombination
BTI247_RS21635	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BTI247_RS21645	COG0142	geranyltranstransferase activity
BTI247_RS21670	COG1302	Protein conserved in bacteria
BTI247_RS21675	COG0439	Biotin carboxylase
BTI247_RS21680	COG0511	ligase activity, forming carbon-carbon bonds
BTI247_RS21720	COG3854	ATPases associated with a variety of cellular activities
BTI247_RS21745	COG0006	proline dipeptidase activity
BTI247_RS21760	COG3872	metal-dependent enzyme
BTI247_RS21770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTI247_RS21805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTI247_RS21815	COG1609	Transcriptional regulator
BTI247_RS21825	COG2076	Multidrug Resistance protein
BTI247_RS21830	COG2076	Multidrug Resistance protein
BTI247_RS21860	COG1131	(ABC) transporter
BTI247_RS21865	COG1725	Transcriptional regulator
BTI247_RS21895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTI247_RS21960	COG1459	type II secretion system
BTI247_RS21965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BTI247_RS22020	COG1410	methionine synthase
BTI247_RS22020	COG0646	methionine synthase
BTI247_RS22025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BTI247_RS22025	COG0646	methionine synthase
BTI247_RS22030	COG0626	cystathionine gamma-synthase activity
BTI247_RS22035	COG0626	cystathionine gamma-synthase activity
BTI247_RS22055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTI247_RS22065	COG1940	carbohydrate kinase activity
BTI247_RS22070	COG4483	Protein conserved in bacteria
BTI247_RS22075	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTI247_RS22080	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BTI247_RS22085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTI247_RS22090	COG0704	Plays a role in the regulation of phosphate uptake
BTI247_RS22110	COG0573	inorganic phosphate transmembrane transporter activity
BTI247_RS22115	COG0573	inorganic phosphate transmembrane transporter activity
BTI247_RS22120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BTI247_RS22125	COG0768	penicillin binding
BTI247_RS22130	COG0477	Major facilitator Superfamily
BTI247_RS22135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTI247_RS22145	COG5521	maltodextrose utilization protein MalA
BTI247_RS22160	COG0735	belongs to the Fur family
BTI247_RS22165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTI247_RS22170	COG1121	(ABC) transporter
BTI247_RS22175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTI247_RS22205	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BTI247_RS22210	COG2384	SAM-dependent methyltransferase
BTI247_RS22220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTI247_RS22225	COG0358	DNA primase activity
BTI247_RS22235	COG0517	IMP dehydrogenase activity
BTI247_RS22250	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BTI247_RS22255	COG0295	cytidine deaminase activity
BTI247_RS22260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BTI247_RS22270	COG1480	7TM receptor with intracellular HD hydrolase
BTI247_RS22275	COG1702	phosphate starvation-inducible protein PhoH
BTI247_RS22295	COG1610	YqeY-like protein
BTI247_RS22300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BTI247_RS22305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTI247_RS22310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BTI247_RS22340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTI247_RS22345	COG1733	regulation of RNA biosynthetic process
BTI247_RS22370	COG1466	dna polymerase III delta subunit
BTI247_RS22380	COG2333	competence protein COMEC
BTI247_RS22380	COG0658	competence protein
BTI247_RS22385	COG2131	deaminase
BTI247_RS22390	COG1555	photosystem II stabilization
BTI247_RS22390	COG1596	polysaccharide export
BTI247_RS22395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTI247_RS22400	COG2226	methyltransferase
BTI247_RS22405	COG0799	negative regulation of ribosome biogenesis
BTI247_RS22410	COG1713	HD superfamily hydrolase involved in NAD metabolism
BTI247_RS22420	COG1534	Rna-binding protein
BTI247_RS22430	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BTI247_RS22435	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BTI247_RS22460	COG1595	DNA-templated transcription, initiation
BTI247_RS22470	COG0778	Nitroreductase
BTI247_RS22475	COG2357	RelA SpoT domain protein
BTI247_RS22485	COG1785	Belongs to the alkaline phosphatase family
BTI247_RS22495	COG2267	carboxylic ester hydrolase activity
BTI247_RS22530	COG1404	Belongs to the peptidase S8 family
BTI247_RS22535	COG3186	Phenylalanine-4-hydroxylase
BTI247_RS22545	COG2514	catechol 2,3-dioxygenase activity
BTI247_RS22550	COG2259	Doxx family
BTI247_RS22590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTI247_RS22600	COG1454	alcohol dehydrogenase
BTI247_RS22600	COG1012	belongs to the aldehyde dehydrogenase family
BTI247_RS22605	COG0626	cystathionine gamma-synthase activity
BTI247_RS22610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTI247_RS22635	COG0768	penicillin binding
BTI247_RS22650	COG0826	peptidase U32
BTI247_RS22655	COG0826	peptidase U32
BTI247_RS22660	COG4122	O-methyltransferase activity
BTI247_RS22665	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BTI247_RS22680	COG4472	Bacterial protein of unknown function (DUF965)
BTI247_RS22695	COG0628	permease
BTI247_RS22715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BTI247_RS22730	COG1104	cysteine desulfurase activity
BTI247_RS22735	COG1959	2 iron, 2 sulfur cluster binding
BTI247_RS22740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BTI247_RS22750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BTI247_RS22780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTI247_RS22790	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BTI247_RS22790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BTI247_RS22795	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTI247_RS22800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTI247_RS22800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTI247_RS22810	COG2244	polysaccharide biosynthetic process
BTI247_RS22815	COG2323	membrane
BTI247_RS22825	COG1862	Preprotein translocase
BTI247_RS22855	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BTI247_RS22885	COG0157	Belongs to the NadC ModD family
BTI247_RS22890	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BTI247_RS22895	COG1104	cysteine desulfurase activity
BTI247_RS22900	COG1827	regulation of RNA biosynthetic process
BTI247_RS22905	COG2258	MOSC domain
BTI247_RS22910	COG0077	Prephenate dehydratase
BTI247_RS22915	COG0577	efflux transmembrane transporter activity
BTI247_RS22920	COG0577	efflux transmembrane transporter activity
BTI247_RS22925	COG1136	(ABC) transporter
BTI247_RS22930	COG5002	protein histidine kinase activity
BTI247_RS22935	COG0745	RESPONSE REGULATOR receiver
BTI247_RS22945	COG3290	protein histidine kinase activity
BTI247_RS22955	COG2868	ribosomal protein
BTI247_RS22965	COG1530	ribonuclease E activity
BTI247_RS22970	COG1994	Peptidase M50
BTI247_RS22975	COG0739	heme binding
BTI247_RS22980	COG2894	cell division
BTI247_RS23000	COG1077	Cell shape determining protein MreB Mrl
BTI247_RS23045	COG2801	Transposase and inactivated derivatives
BTI247_RS23100	COG2824	Alkylphosphonate utilization operon protein PhnA
BTI247_RS23115	COG0659	secondary active sulfate transmembrane transporter activity
BTI247_RS23130	COG4990	cell redox homeostasis
BTI247_RS23150	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS23175	COG0285	dihydrofolate synthase activity
BTI247_RS23190	COG1388	LysM domain
BTI247_RS23200	COG0113	porphobilinogen synthase activity
BTI247_RS23205	COG1587	Uroporphyrinogen-III synthase
BTI247_RS23215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTI247_RS23225	COG1846	Transcriptional regulator
BTI247_RS23230	COG1764	response to oxidative stress
BTI247_RS23245	COG0470	DNA polymerase III
BTI247_RS23245	COG1067	ATP-dependent peptidase activity
BTI247_RS23300	COG0622	Phosphoesterase
BTI247_RS23315	COG5401	PFAM Sporulation and spore germination
BTI247_RS23335	COG2197	response regulator
BTI247_RS23340	COG2233	PERMEase
BTI247_RS23345	COG0402	S-adenosylhomocysteine deaminase activity
BTI247_RS23350	COG1983	PspC domain protein
BTI247_RS23355	COG1396	sequence-specific DNA binding
BTI247_RS23360	COG0697	spore germination
BTI247_RS23370	COG1959	2 iron, 2 sulfur cluster binding
BTI247_RS23375	COG1668	transmembrane transport
BTI247_RS23380	COG4152	abc transporter atp-binding protein
BTI247_RS23385	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BTI247_RS23390	COG1360	Flagellar Motor Protein
BTI247_RS23395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BTI247_RS23400	COG1876	peptidase activity
BTI247_RS23405	COG0824	Thioesterase
BTI247_RS23410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BTI247_RS23415	COG1053	succinate dehydrogenase
BTI247_RS23420	COG2009	succinate dehydrogenase
BTI247_RS23425	COG1719	4-vinyl reductase, 4VR
BTI247_RS23435	COG3118	belongs to the thioredoxin family
BTI247_RS23440	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BTI247_RS23445	COG2086	electron transfer activity
BTI247_RS23450	COG1024	Enoyl-CoA hydratase
BTI247_RS23455	COG1309	transcriptional regulator
BTI247_RS23460	COG0318	PFAM AMP-dependent synthetase and ligase
BTI247_RS23475	COG2801	Transposase and inactivated derivatives
BTI247_RS23500	COG2318	DinB family
BTI247_RS23525	COG1131	(ABC) transporter
BTI247_RS23530	COG2205	protein histidine kinase activity
BTI247_RS23535	COG0745	RESPONSE REGULATOR receiver
BTI247_RS23545	COG4895	conserved protein (DUF2196)
BTI247_RS23550	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BTI247_RS23560	COG4509	Sortase family
BTI247_RS23565	COG1120	ATPase activity
BTI247_RS23580	COG5386	Cell surface protein
BTI247_RS23590	COG5386	Cell surface protein
BTI247_RS23595	COG1114	Component of the transport system for branched-chain amino acids
BTI247_RS23600	COG1187	pseudouridine synthase activity
BTI247_RS23610	COG1796	DNA polymerase
BTI247_RS23610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTI247_RS23615	COG1286	toxin biosynthetic process
BTI247_RS23655	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BTI247_RS23660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTI247_RS23670	COG1418	mRNA catabolic process
BTI247_RS23690	COG2814	Major facilitator Superfamily
BTI247_RS23695	COG1566	PFAM secretion protein HlyD family protein
BTI247_RS23700	COG1309	transcriptional regulator
BTI247_RS23705	COG1363	Peptidase, m42
BTI247_RS23730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTI247_RS23745	COG1484	DNA-dependent DNA replication
BTI247_RS23750	COG3611	Membrane attachment protein
BTI247_RS23760	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BTI247_RS23765	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTI247_RS23770	COG0237	dephospho-CoA kinase activity
BTI247_RS23775	COG1971	Probably functions as a manganese efflux pump
BTI247_RS23785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTI247_RS23785	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTI247_RS23790	COG5002	protein histidine kinase activity
BTI247_RS23795	COG0745	RESPONSE REGULATOR receiver
BTI247_RS23815	COG0538	isocitrate dehydrogenase activity
BTI247_RS23820	COG0372	Belongs to the citrate synthase family
BTI247_RS23830	COG0628	permease
BTI247_RS23835	COG3030	protein affecting phage T7 exclusion by the F plasmid
BTI247_RS23860	COG1725	Transcriptional regulator
BTI247_RS23865	COG0281	malic enzyme
BTI247_RS23870	COG0587	DNA-directed DNA polymerase activity
BTI247_RS23885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BTI247_RS23900	COG4109	DRTGG domain
BTI247_RS23915	COG0006	proline dipeptidase activity
BTI247_RS23955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTI247_RS23960	COG0662	Cupin 2, conserved barrel domain protein
BTI247_RS23975	COG1028	Short-chain dehydrogenase reductase Sdr
BTI247_RS23980	COG0589	response to stress
BTI247_RS24020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTI247_RS24045	COG0827	DNA restriction-modification system
BTI247_RS24050	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BTI247_RS24055	COG0464	growth
BTI247_RS24060	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS24070	COG3874	Sporulation protein YtfJ
BTI247_RS24085	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BTI247_RS24095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTI247_RS24110	COG1104	cysteine desulfurase activity
BTI247_RS24120	COG0583	DNA-binding transcription factor activity
BTI247_RS24125	COG0697	spore germination
BTI247_RS24130	COG1309	transcriptional regulator
BTI247_RS24135	COG1956	GAF domain-containing protein
BTI247_RS24140	COG0626	cystathionine gamma-synthase activity
BTI247_RS24175	COG1595	DNA-templated transcription, initiation
BTI247_RS24185	COG0110	maltose O-acetyltransferase activity
BTI247_RS24190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTI247_RS24195	COG0454	-acetyltransferase
BTI247_RS24200	COG0517	IMP dehydrogenase activity
BTI247_RS24205	COG0123	including yeast histone deacetylase and acetoin utilization protein
BTI247_RS24215	COG0745	RESPONSE REGULATOR receiver
BTI247_RS24220	COG5002	protein histidine kinase activity
BTI247_RS24225	COG0666	response to abiotic stimulus
BTI247_RS24255	COG1609	Transcriptional regulator
BTI247_RS24260	COG1605	Chorismate mutase
BTI247_RS24260	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTI247_RS24265	COG1605	Chorismate mutase
BTI247_RS24265	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTI247_RS24270	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTI247_RS24270	COG1605	Chorismate mutase
BTI247_RS24275	COG4851	CamS sex pheromone cAM373 precursor
BTI247_RS24280	COG3118	belongs to the thioredoxin family
BTI247_RS24290	COG2309	aminopeptidase activity
BTI247_RS24305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTI247_RS24320	COG1674	ftsk spoiiie
BTI247_RS24335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTI247_RS24345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTI247_RS24350	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BTI247_RS24355	COG1363	Peptidase, m42
BTI247_RS24365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTI247_RS24380	COG0510	thiamine kinase activity
BTI247_RS24385	COG1523	belongs to the glycosyl hydrolase 13 family
BTI247_RS24395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTI247_RS24400	COG1349	DNA-binding transcription factor activity
BTI247_RS24405	COG1187	pseudouridine synthase activity
BTI247_RS24410	COG2244	polysaccharide biosynthetic process
BTI247_RS24415	COG2081	HI0933 family
BTI247_RS24420	COG2814	Major facilitator Superfamily
BTI247_RS24430	COG3832	glyoxalase III activity
BTI247_RS24460	COG1329	Transcriptional regulator
BTI247_RS24485	COG0314	molybdopterin synthase activity
BTI247_RS24490	COG1763	Mo-molybdopterin cofactor biosynthetic process
BTI247_RS24495	COG0303	'Molybdopterin
BTI247_RS24505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTI247_RS24510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTI247_RS24530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTI247_RS24540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTI247_RS24580	COG2814	Major facilitator Superfamily
BTI247_RS24585	COG0475	glutathione-regulated potassium exporter activity
BTI247_RS24590	COG0490	domain, Protein
BTI247_RS24595	COG0582	viral genome integration into host DNA
BTI247_RS24605	COG1136	(ABC) transporter
BTI247_RS24625	COG1242	4 iron, 4 sulfur cluster binding
BTI247_RS24630	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BTI247_RS24635	COG1794	racemase activity, acting on amino acids and derivatives
BTI247_RS24655	COG2267	carboxylic ester hydrolase activity
BTI247_RS24660	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTI247_RS24665	COG0671	phosphoesterase, PA-phosphatase related
BTI247_RS24670	COG0438	transferase activity, transferring glycosyl groups
BTI247_RS24750	COG5002	protein histidine kinase activity
BTI247_RS24755	COG3852	Histidine kinase
BTI247_RS24760	COG0753	catalase activity
BTI247_RS24765	COG2267	carboxylic ester hydrolase activity
BTI247_RS24770	COG1368	sulfuric ester hydrolase activity
BTI247_RS24785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTI247_RS24790	COG1116	anion transmembrane transporter activity
BTI247_RS24795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTI247_RS24820	COG0494	nUDIX hydrolase
BTI247_RS24850	COG1854	S-ribosylhomocysteine lyase activity
BTI247_RS24860	COG0288	reversible hydration of carbon dioxide
BTI247_RS24865	COG1271	oxidase subunit
BTI247_RS24870	COG1294	oxidase, subunit
BTI247_RS24890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTI247_RS24910	COG1842	Phage shock protein A
BTI247_RS24950	COG3859	Proton-coupled thiamine transporter YuaJ
BTI247_RS24955	COG5002	protein histidine kinase activity
BTI247_RS24960	COG0745	RESPONSE REGULATOR receiver
BTI247_RS24985	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTI247_RS24990	COG1597	lipid kinase activity
BTI247_RS25030	COG0577	efflux transmembrane transporter activity
BTI247_RS25035	COG1136	(ABC) transporter
BTI247_RS25050	COG0586	Pfam SNARE associated Golgi protein
BTI247_RS25060	COG0577	efflux transmembrane transporter activity
BTI247_RS25065	COG1136	(ABC) transporter
BTI247_RS25070	COG2207	Transcriptional regulator
BTI247_RS25070	COG3708	Transcriptional regulator
BTI247_RS25075	COG5658	integral membrane protein
BTI247_RS25080	COG0640	Transcriptional regulator
BTI247_RS25085	COG0745	RESPONSE REGULATOR receiver
BTI247_RS25090	COG2205	protein histidine kinase activity
BTI247_RS25095	COG0577	efflux transmembrane transporter activity
BTI247_RS25100	COG0577	efflux transmembrane transporter activity
BTI247_RS25105	COG1136	(ABC) transporter
BTI247_RS25110	COG0577	efflux transmembrane transporter activity
BTI247_RS25135	COG2188	Transcriptional regulator
BTI247_RS25155	COG3964	amidohydrolase
BTI247_RS25175	COG4948	Mandelate Racemase Muconate Lactonizing
BTI247_RS25185	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BTI247_RS25190	COG0596	Alpha beta hydrolase
BTI247_RS25200	COG1169	isochorismate synthase
BTI247_RS25205	COG1575	Belongs to the MenA family. Type 1 subfamily
BTI247_RS25210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BTI247_RS25215	COG1278	Cold shock
BTI247_RS25240	COG0058	SHG alpha-glucan phosphorylase activity
BTI247_RS25250	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BTI247_RS25270	COG1404	Belongs to the peptidase S8 family
BTI247_RS25415	COG1285	pathogenesis
BTI247_RS25420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTI247_RS25435	COG2155	Conserved Protein
BTI247_RS25440	COG1098	S1 RNA binding domain
BTI247_RS25445	COG0436	Aminotransferase
BTI247_RS25450	COG1522	sequence-specific DNA binding
BTI247_RS25455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTI247_RS25460	COG2267	carboxylic ester hydrolase activity
BTI247_RS25470	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BTI247_RS25490	COG5018	Exonuclease
BTI247_RS25495	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTI247_RS25515	COG2050	protein possibly involved in aromatic compounds catabolism
BTI247_RS25525	COG1268	BioY protein
BTI247_RS25530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTI247_RS25535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTI247_RS25550	COG3584	3D domain protein
BTI247_RS25565	COG1252	NADH dehydrogenase
BTI247_RS25580	COG3708	Transcriptional regulator
BTI247_RS25595	COG1683	Conserved Protein
BTI247_RS25605	COG4122	O-methyltransferase activity
BTI247_RS25620	COG0316	Belongs to the HesB IscA family
BTI247_RS25635	COG1252	NADH dehydrogenase
BTI247_RS25650	COG0390	transport system, permease component
BTI247_RS25655	COG2824	Alkylphosphonate utilization operon protein PhnA
BTI247_RS25705	COG4837	Protein of unknown function (DUF1462)
BTI247_RS25710	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BTI247_RS25720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTI247_RS25725	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BTI247_RS25745	COG1358	cellular component organization or biogenesis
BTI247_RS25755	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTI247_RS25760	COG0647	UMP catabolic process
BTI247_RS25770	COG2445	Protein of unknown function DUF86
BTI247_RS25775	COG1494	fructose-1,6-bisphosphatase
BTI247_RS25790	COG4470	Protein conserved in bacteria
BTI247_RS25800	COG0789	Transcriptional regulator
BTI247_RS25805	COG4377	Putative membrane peptidase family (DUF2324)
BTI247_RS25830	COG0739	heme binding
BTI247_RS25840	COG3377	Domain of unknown function (DUF1805)
BTI247_RS25845	COG0737	Belongs to the 5'-nucleotidase family
BTI247_RS25850	COG0719	Fe-S assembly protein
BTI247_RS25855	COG0822	iron-sulfur transferase activity
BTI247_RS25860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BTI247_RS25865	COG0719	Fe-S assembly protein
BTI247_RS25870	COG0396	ATPase activity
BTI247_RS25875	COG1464	Belongs to the NlpA lipoprotein family
BTI247_RS25880	COG1464	Belongs to the NlpA lipoprotein family
BTI247_RS25885	COG2011	ABC-type metal ion transport system permease component
BTI247_RS25900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTI247_RS25905	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BTI247_RS25910	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS25920	COG1393	Belongs to the ArsC family
BTI247_RS25940	COG0039	L-malate dehydrogenase activity
BTI247_RS25960	COG2801	Transposase and inactivated derivatives
BTI247_RS25970	COG1309	transcriptional regulator
BTI247_RS25975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTI247_RS25980	COG1960	acyl-CoA dehydrogenase activity
BTI247_RS25985	COG0183	Belongs to the thiolase family
BTI247_RS25990	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTI247_RS25990	COG1024	Enoyl-CoA hydratase
BTI247_RS26000	COG1686	Belongs to the peptidase S11 family
BTI247_RS26015	COG0011	TIGRFAM Protein of
BTI247_RS26020	COG0840	transmembrane signaling receptor activity
BTI247_RS26035	COG2814	Major facilitator Superfamily
BTI247_RS26040	COG0531	amino acid
BTI247_RS26065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTI247_RS26100	COG0586	Pfam SNARE associated Golgi protein
BTI247_RS26110	COG1376	ErfK ybiS ycfS ynhG family protein
BTI247_RS26115	COG0745	RESPONSE REGULATOR receiver
BTI247_RS26120	COG5002	protein histidine kinase activity
BTI247_RS26140	COG0840	transmembrane signaling receptor activity
BTI247_RS26145	COG2151	metal-sulfur cluster biosynthetic enzyme
BTI247_RS26150	COG3227	Zinc metalloprotease (Elastase)
BTI247_RS26155	COG1741	Belongs to the pirin family
BTI247_RS26170	COG0586	Pfam SNARE associated Golgi protein
BTI247_RS26175	COG0475	glutathione-regulated potassium exporter activity
BTI247_RS26180	COG0490	domain, Protein
BTI247_RS26185	COG1115	amino acid carrier protein
BTI247_RS26195	COG2801	Transposase and inactivated derivatives
BTI247_RS26200	COG1115	amino acid carrier protein
BTI247_RS26205	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS26210	COG0783	Belongs to the Dps family
BTI247_RS26230	COG1611	Belongs to the LOG family
BTI247_RS26240	COG1528	Iron-storage protein
BTI247_RS26245	COG2311	Membrane
BTI247_RS26250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTI247_RS26260	COG1115	amino acid carrier protein
BTI247_RS26265	COG1115	amino acid carrier protein
BTI247_RS26270	COG2910	NAD(P)H-binding
BTI247_RS26285	COG0656	L-ascorbic acid biosynthetic process
BTI247_RS26290	COG2814	Major facilitator Superfamily
BTI247_RS26295	COG1733	regulation of RNA biosynthetic process
BTI247_RS26305	COG1252	NADH dehydrogenase
BTI247_RS26360	COG0488	(ABC) transporter
BTI247_RS26365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTI247_RS26450	COG0557	exoribonuclease II activity
BTI247_RS26455	COG1647	Serine aminopeptidase, S33
BTI247_RS26460	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTI247_RS26465	COG1346	cytolysis
BTI247_RS26500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTI247_RS26515	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BTI247_RS26540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTI247_RS26555	COG2323	membrane
BTI247_RS26565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTI247_RS26575	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BTI247_RS26585	COG1051	belongs to the nudix hydrolase family
BTI247_RS26715	COG4733	cellulase activity
BTI247_RS26715	COG5297	Belongs to the glycosyl hydrolase family 6
BTI247_RS26725	COG0740	serine-type endopeptidase activity
BTI247_RS26735	COG1802	Transcriptional regulator
BTI247_RS26735	COG4626	Terminase
BTI247_RS26740	COG5484	DNA packaging
BTI247_RS26775	COG0582	viral genome integration into host DNA
BTI247_RS26790	COG3617	BRO family, N-terminal domain
BTI247_RS26845	COG1396	sequence-specific DNA binding
BTI247_RS26860	COG0492	ferredoxin-NADP+ reductase activity
BTI247_RS26865	COG0457	Tetratricopeptide repeat
BTI247_RS26870	COG0110	maltose O-acetyltransferase activity
BTI247_RS26890	COG1950	PFAM Membrane protein of
BTI247_RS26895	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BTI247_RS26915	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS26920	COG0789	Transcriptional regulator
BTI247_RS26950	COG0583	DNA-binding transcription factor activity
BTI247_RS26960	COG0655	NAD(P)H dehydrogenase (quinone) activity
BTI247_RS26965	COG0488	(ABC) transporter
BTI247_RS26975	COG1132	(ABC) transporter
BTI247_RS26980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTI247_RS26985	COG3409	Peptidoglycan-binding domain 1 protein
BTI247_RS26985	COG0793	Belongs to the peptidase S41A family
BTI247_RS26990	COG2177	Part of the ABC transporter FtsEX involved in
BTI247_RS26995	COG2884	Cell division ATP-binding protein ftsE
BTI247_RS27005	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BTI247_RS27015	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BTI247_RS27020	COG1278	Cold shock
BTI247_RS27025	COG1040	competence protein
BTI247_RS27030	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BTI247_RS27035	COG1388	LysM domain
BTI247_RS27035	COG0791	NLP P60 protein
BTI247_RS27040	COG1733	regulation of RNA biosynthetic process
BTI247_RS27045	COG1307	EDD domain protein, DegV family
BTI247_RS27050	COG1739	Uncharacterized protein family UPF0029
BTI247_RS27055	COG1316	TRANSCRIPTIONal
BTI247_RS27060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BTI247_RS27065	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BTI247_RS27075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTI247_RS27085	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BTI247_RS27085	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BTI247_RS27105	COG1486	melibiose metabolic process
BTI247_RS27110	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTI247_RS27115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTI247_RS27135	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTI247_RS27145	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS27155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTI247_RS27160	COG1301	dicarboxylic acid transport
BTI247_RS27175	COG1511	domain protein
BTI247_RS27180	COG0583	DNA-binding transcription factor activity
BTI247_RS27185	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BTI247_RS27195	COG1271	oxidase subunit
BTI247_RS27200	COG1294	oxidase, subunit
BTI247_RS27210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTI247_RS27235	COG1620	l-lactate permease
BTI247_RS27245	COG2389	metal-binding protein
BTI247_RS27255	COG1368	sulfuric ester hydrolase activity
BTI247_RS27265	COG0791	NLP P60 protein
BTI247_RS27265	COG1388	LysM domain
BTI247_RS27270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTI247_RS27280	COG1215	transferase activity, transferring glycosyl groups
BTI247_RS27290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTI247_RS27295	COG1388	LysM domain
BTI247_RS27295	COG3584	3D domain protein
BTI247_RS27320	COG4715	Zinc finger, swim domain protein
BTI247_RS27325	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTI247_RS27365	COG0577	efflux transmembrane transporter activity
BTI247_RS27370	COG1136	(ABC) transporter
BTI247_RS27410	COG0745	RESPONSE REGULATOR receiver
BTI247_RS27415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTI247_RS27425	COG1316	TRANSCRIPTIONal
BTI247_RS27435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BTI247_RS27450	COG0438	transferase activity, transferring glycosyl groups
BTI247_RS27460	COG0438	transferase activity, transferring glycosyl groups
BTI247_RS27465	COG0438	transferase activity, transferring glycosyl groups
BTI247_RS27475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTI247_RS27480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BTI247_RS27485	COG1086	Polysaccharide biosynthesis protein
BTI247_RS27490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTI247_RS27495	COG4464	protein tyrosine phosphatase activity
BTI247_RS27500	COG0489	protein tyrosine kinase activity
BTI247_RS27505	COG3944	biosynthesis protein
BTI247_RS27510	COG0489	protein tyrosine kinase activity
BTI247_RS27525	COG1609	Transcriptional regulator
BTI247_RS27535	COG0739	heme binding
BTI247_RS27550	COG4555	ABC transporter
BTI247_RS27555	COG2385	sporulation resulting in formation of a cellular spore
BTI247_RS27570	COG4836	Membrane
BTI247_RS27575	COG1007	ATP synthesis coupled electron transport
BTI247_RS27580	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTI247_RS27585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTI247_RS27595	COG0839	Belongs to the complex I subunit 6 family
BTI247_RS27615	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTI247_RS27630	COG3300	MHYT domain
BTI247_RS27630	COG5001	Diguanylate cyclase
BTI247_RS27680	COG0356	it plays a direct role in the translocation of protons across the membrane
BTI247_RS27715	COG0698	ribose 5-phosphate isomerase
BTI247_RS27725	COG2190	(PTS) system
BTI247_RS27730	COG2259	Doxx family
BTI247_RS27735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTI247_RS27750	COG0009	L-threonylcarbamoyladenylate synthase
BTI247_RS27785	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BTI247_RS27790	COG1494	fructose-1,6-bisphosphatase
BTI247_RS27810	COG4821	SIS domain
BTI247_RS27820	COG3343	RNA polymerase activity
BTI247_RS27830	COG1960	acyl-CoA dehydrogenase activity
BTI247_RS27835	COG1960	acyl-CoA dehydrogenase activity
BTI247_RS27840	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTI247_RS27845	COG0183	Belongs to the thiolase family
BTI247_RS27850	COG0247	lactate metabolic process
BTI247_RS27850	COG2181	nitrate reductase activity
BTI247_RS27855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTI247_RS27865	COG5001	Diguanylate cyclase
BTI247_RS27865	COG3300	MHYT domain
BTI247_RS27880	COG3227	Zinc metalloprotease (Elastase)
BTI247_RS27885	COG2197	response regulator
BTI247_RS27890	COG4585	Histidine kinase
BTI247_RS27895	COG0842	Transport permease protein
BTI247_RS27900	COG1131	(ABC) transporter
BTI247_RS27905	COG0024	Methionine aminopeptidase
BTI247_RS27915	COG2234	aminopeptidase activity
BTI247_RS27935	COG1595	DNA-templated transcription, initiation
BTI247_RS27945	COG4506	Protein conserved in bacteria
BTI247_RS27950	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTI247_RS27975	COG2814	Major facilitator Superfamily
BTI247_RS27980	COG0789	Transcriptional regulator
BTI247_RS27985	COG0584	glycerophosphoryl diester phosphodiesterase
BTI247_RS27990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTI247_RS28000	COG1994	Peptidase M50
BTI247_RS28010	COG1078	dGTPase activity
BTI247_RS28015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTI247_RS28020	COG1120	ATPase activity
BTI247_RS28025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTI247_RS28030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTI247_RS28050	COG0280	phosphate acetyltransferase
BTI247_RS28065	COG3773	Cell wall hydrolase
BTI247_RS28075	COG2363	Small membrane protein
BTI247_RS28085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTI247_RS28090	COG2233	PERMEase
BTI247_RS28095	COG0561	phosphatase activity
BTI247_RS28100	COG2814	Major facilitator Superfamily
BTI247_RS28110	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BTI247_RS28115	COG1131	(ABC) transporter
BTI247_RS28120	COG2755	lipolytic protein G-D-S-L family
BTI247_RS28125	COG1609	Transcriptional regulator
BTI247_RS28135	COG0460	homoserine dehydrogenase
BTI247_RS28145	COG2873	o-acetylhomoserine
BTI247_RS28155	COG1011	Hydrolase
BTI247_RS28160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTI247_RS28170	COG2197	response regulator
BTI247_RS28175	COG2203	Gaf domain
BTI247_RS28175	COG4585	Histidine kinase
BTI247_RS28180	COG0351	phosphomethylpyrimidine kinase
BTI247_RS28185	COG3706	GGDEF domain
BTI247_RS28190	COG2879	small protein
BTI247_RS28195	COG1966	Carbon starvation protein
BTI247_RS28200	COG3279	Response regulator of the LytR AlgR family
BTI247_RS28205	COG0477	Major facilitator Superfamily
BTI247_RS28215	COG0438	transferase activity, transferring glycosyl groups
BTI247_RS28230	COG0840	transmembrane signaling receptor activity
BTI247_RS28240	COG1607	acyl-coa hydrolase
BTI247_RS28250	COG1216	Glycosyl transferase, family 2
BTI247_RS28260	COG0488	(ABC) transporter
BTI247_RS28275	COG0463	Glycosyl transferase, family 2
BTI247_RS28280	COG1309	transcriptional regulator
BTI247_RS28285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTI247_RS28290	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTI247_RS28290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTI247_RS28295	COG0628	permease
BTI247_RS28320	COG3547	Transposase (IS116 IS110 IS902 family)
BTI247_RS28325	COG3275	phosphorelay sensor kinase activity
BTI247_RS28330	COG2814	Major facilitator Superfamily
BTI247_RS28335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTI247_RS28340	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BTI247_RS28365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTI247_RS28370	COG1272	protein, Hemolysin III
BTI247_RS28395	COG1164	Oligoendopeptidase f
BTI247_RS28405	COG5002	protein histidine kinase activity
BTI247_RS28420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTI247_RS28425	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BTI247_RS28430	COG4853	Protein conserved in bacteria
BTI247_RS28440	COG5002	protein histidine kinase activity
BTI247_RS28445	COG0745	RESPONSE REGULATOR receiver
BTI247_RS28475	COG0305	Participates in initiation and elongation during chromosome replication
BTI247_RS28485	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BTI247_RS28490	COG4241	membrane
BTI247_RS28500	COG0629	single-stranded DNA binding
BTI247_RS28510	COG0012	GTP binding
BTI247_RS28515	COG4481	Protein conserved in bacteria
BTI247_RS28520	COG0668	transmembrane transport
BTI247_RS28530	COG1475	DNA binding
BTI247_RS28535	COG1192	Involved in chromosome partitioning
BTI247_RS28560	COG1847	R3H domain protein
BTI247_RS28575	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BTI247_RS28590	COG0592	DNA-directed DNA polymerase activity
BTI247_RS28880	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTI247_RS28990	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BTI247_RS29510	COG0187	DNA topoisomerase II activity
BTI247_RS29775	COG2208	phosphoserine phosphatase activity
BTI247_RS29960	COG0542	response to heat
BTI247_RS30360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BTI247_RS30405	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTI247_RS30465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTI247_RS30730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTI247_RS31005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTI247_RS31110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTI247_RS31165	COG0592	DNA-directed DNA polymerase activity
BTI247_RS31200	COG0592	DNA-directed DNA polymerase activity
BTI247_RS31220	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner