locus-tag	class	description
AXW78_RS00010	COG0592	DNA-directed DNA polymerase activity
AXW78_RS00015	COG2501	S4 domain
AXW78_RS00025	COG0187	DNA topoisomerase II activity
AXW78_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXW78_RS00065	COG0516	GMP reductase activity
AXW78_RS00065	COG0517	IMP dehydrogenase activity
AXW78_RS00070	COG1686	Belongs to the peptidase S11 family
AXW78_RS00100	COG1428	Deoxynucleoside kinase
AXW78_RS00105	COG1428	Deoxynucleoside kinase
AXW78_RS00110	COG1335	isochorismatase
AXW78_RS00115	COG0590	tRNA wobble adenosine to inosine editing
AXW78_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AXW78_RS00180	COG1982	Orn Lys Arg decarboxylase major
AXW78_RS00190	COG0470	DNA polymerase III
AXW78_RS00195	COG1774	PSP1 C-terminal conserved region
AXW78_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AXW78_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AXW78_RS00220	COG2002	toxin-antitoxin pair type II binding
AXW78_RS00230	COG0084	hydrolase, TatD family'
AXW78_RS00250	COG4466	Protein conserved in bacteria
AXW78_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AXW78_RS00270	COG0251	oxidation-reduction process
AXW78_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXW78_RS00305	COG2002	toxin-antitoxin pair type II binding
AXW78_RS00310	COG2244	polysaccharide biosynthetic process
AXW78_RS00315	COG3956	TIGRFAM MazG family protein
AXW78_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AXW78_RS00340	COG1098	S1 RNA binding domain
AXW78_RS00355	COG2208	phosphoserine phosphatase activity
AXW78_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AXW78_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXW78_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AXW78_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXW78_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
AXW78_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXW78_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AXW78_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AXW78_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AXW78_RS00420	COG1396	sequence-specific DNA binding
AXW78_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXW78_RS00515	COG3880	PFAM UvrB UvrC protein
AXW78_RS00525	COG0542	response to heat
AXW78_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AXW78_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
AXW78_RS00560	COG1045	serine acetyltransferase
AXW78_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXW78_RS00580	COG3688	RNA-binding protein containing a PIN domain
AXW78_RS00590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AXW78_RS00595	COG0250	Participates in transcription elongation, termination and antitermination
AXW78_RS00600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AXW78_RS00620	COG2813	Specifically methylates the guanine in position
AXW78_RS00635	COG1358	cellular component organization or biogenesis
AXW78_RS00640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AXW78_RS00705	COG0255	Belongs to the universal ribosomal protein uL29 family
AXW78_RS00765	COG0201	protein transport
AXW78_RS00775	COG0024	Methionine aminopeptidase
AXW78_RS00785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AXW78_RS00820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AXW78_RS00845	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXW78_RS00850	COG0489	protein tyrosine kinase activity
AXW78_RS00860	COG2194	sulfuric ester hydrolase activity
AXW78_RS00865	COG0726	polysaccharide deacetylase
AXW78_RS00945	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AXW78_RS00950	COG4856	YbbR-like protein
AXW78_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS00995	COG2011	ABC-type metal ion transport system permease component
AXW78_RS01000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXW78_RS01005	COG1464	Belongs to the NlpA lipoprotein family
AXW78_RS01010	COG0604	alcohol dehydrogenase
AXW78_RS01025	COG2271	Major facilitator Superfamily
AXW78_RS01035	COG2814	Major facilitator Superfamily
AXW78_RS01050	COG2207	Transcriptional regulator
AXW78_RS01070	COG4166	transmembrane transport
AXW78_RS01075	COG0656	L-ascorbic acid biosynthetic process
AXW78_RS01090	COG4149	molybdate abc transporter
AXW78_RS01095	COG0725	ABC transporter, periplasmic molybdate-binding protein
AXW78_RS01100	COG1910	domain protein
AXW78_RS01110	COG0697	spore germination
AXW78_RS01120	COG0204	Acyl-transferase
AXW78_RS01125	COG1609	Transcriptional regulator
AXW78_RS01135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXW78_RS01155	COG5298	Protein conserved in bacteria
AXW78_RS01175	COG0488	(ABC) transporter
AXW78_RS01185	COG0747	negative chemotaxis
AXW78_RS01190	COG0601	transmembrane transport
AXW78_RS01195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW78_RS01200	COG0444	Belongs to the ABC transporter superfamily
AXW78_RS01205	COG4608	Belongs to the ABC transporter superfamily
AXW78_RS01210	COG0561	phosphatase activity
AXW78_RS01235	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AXW78_RS01240	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXW78_RS01250	COG0531	amino acid
AXW78_RS01255	COG2814	Major facilitator Superfamily
AXW78_RS01265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AXW78_RS01275	COG4294	response to UV
AXW78_RS01280	COG0705	Rhomboid family
AXW78_RS01290	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AXW78_RS01295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AXW78_RS01300	COG0864	Transcriptional regulator
AXW78_RS01305	COG2337	Toxic component of a toxin-antitoxin (TA) module
AXW78_RS01310	COG2183	response to ionizing radiation
AXW78_RS01400	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AXW78_RS01430	COG0802	atpase or kinase
AXW78_RS01435	COG1214	PFAM Peptidase M22, glycoprotease
AXW78_RS01440	COG0456	acetyltransferase
AXW78_RS01450	COG0488	(ABC) transporter
AXW78_RS01465	COG1266	CAAX protease self-immunity
AXW78_RS01485	COG2252	PERMEase
AXW78_RS01495	COG5002	protein histidine kinase activity
AXW78_RS01525	COG2226	methyltransferase
AXW78_RS01545	COG1215	transferase activity, transferring glycosyl groups
AXW78_RS01585	COG2205	protein histidine kinase activity
AXW78_RS01590	COG0745	RESPONSE REGULATOR receiver
AXW78_RS01610	COG0697	spore germination
AXW78_RS01635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AXW78_RS01640	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AXW78_RS01645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AXW78_RS01655	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AXW78_RS01670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AXW78_RS01680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AXW78_RS01690	COG0151	Belongs to the GarS family
AXW78_RS01715	COG0210	DNA helicase
AXW78_RS01725	COG4851	CamS sex pheromone cAM373 precursor
AXW78_RS01740	COG1335	isochorismatase
AXW78_RS01750	COG2011	ABC-type metal ion transport system permease component
AXW78_RS01755	COG1464	Belongs to the NlpA lipoprotein family
AXW78_RS01760	COG1846	Transcriptional regulator
AXW78_RS01765	COG4682	membrane
AXW78_RS01785	COG1597	lipid kinase activity
AXW78_RS01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXW78_RS01805	COG1012	belongs to the aldehyde dehydrogenase family
AXW78_RS01810	COG2076	Multidrug Resistance protein
AXW78_RS01820	COG2309	aminopeptidase activity
AXW78_RS01835	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXW78_RS01845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXW78_RS01850	COG4807	Protein conserved in bacteria
AXW78_RS01875	COG1757	Na H antiporter
AXW78_RS01880	COG1473	amidohydrolase
AXW78_RS01895	COG0450	alkyl hydroperoxide reductase
AXW78_RS01905	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AXW78_RS01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW78_RS01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW78_RS01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXW78_RS01930	COG0492	ferredoxin-NADP+ reductase activity
AXW78_RS01940	COG0166	Belongs to the GPI family
AXW78_RS01965	COG5002	protein histidine kinase activity
AXW78_RS01985	COG3541	Predicted nucleotidyltransferase
AXW78_RS01990	COG2814	Major facilitator Superfamily
AXW78_RS01995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW78_RS01995	COG0723	plastoquinol--plastocyanin reductase activity
AXW78_RS02005	COG0765	amino acid transport
AXW78_RS02010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW78_RS02020	COG0840	transmembrane signaling receptor activity
AXW78_RS02045	COG0549	Belongs to the carbamate kinase family
AXW78_RS02050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW78_RS02060	COG0366	Alpha amylase catalytic
AXW78_RS02065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXW78_RS02065	COG1263	PTS System
AXW78_RS02065	COG2190	(PTS) system
AXW78_RS02095	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AXW78_RS02115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW78_RS02120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW78_RS02125	COG1116	anion transmembrane transporter activity
AXW78_RS02170	COG2270	Major facilitator Superfamily
AXW78_RS02200	COG2310	stress, protein
AXW78_RS02205	COG2310	stress, protein
AXW78_RS02210	COG2310	stress, protein
AXW78_RS02215	COG0861	Integral membrane protein TerC family
AXW78_RS02225	COG3853	Toxic anion resistance protein (TelA)
AXW78_RS02240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AXW78_RS02250	COG1295	ribonuclease BN
AXW78_RS02255	COG2217	Heavy metal translocating P-type atpase
AXW78_RS02260	COG0697	spore germination
AXW78_RS02280	COG0586	Pfam SNARE associated Golgi protein
AXW78_RS02295	COG3871	stress protein (general stress protein 26)
AXW78_RS02300	COG0387	Pfam Sodium calcium exchanger
AXW78_RS02310	COG0535	radical SAM domain protein
AXW78_RS02330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AXW78_RS02350	COG3829	transcription factor binding
AXW78_RS02360	COG0833	amino acid
AXW78_RS02365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXW78_RS02390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXW78_RS02390	COG1263	PTS System
AXW78_RS02395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXW78_RS02410	COG0463	Glycosyl transferase, family 2
AXW78_RS02420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW78_RS02420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AXW78_RS02435	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AXW78_RS02455	COG1228	amidohydrolase
AXW78_RS02460	COG1090	epimerase
AXW78_RS02490	COG1988	membrane-bound metal-dependent
AXW78_RS02495	COG1194	a g-specific adenine glycosylase
AXW78_RS02520	COG1132	(ABC) transporter
AXW78_RS02525	COG4129	membrane
AXW78_RS02530	COG0067	glutamate synthase
AXW78_RS02530	COG0069	glutamate synthase activity
AXW78_RS02530	COG0070	glutamate synthase
AXW78_RS02540	COG4555	ABC transporter
AXW78_RS02560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AXW78_RS02565	COG0735	belongs to the Fur family
AXW78_RS02685	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AXW78_RS02710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AXW78_RS02715	COG5001	Diguanylate cyclase
AXW78_RS02715	COG1716	ATPase activity
AXW78_RS02720	COG2766	serine protein kinase
AXW78_RS02735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXW78_RS02745	COG1585	Membrane protein implicated in regulation of membrane protease activity
AXW78_RS02750	COG2268	Band 7 protein
AXW78_RS02760	COG3290	protein histidine kinase activity
AXW78_RS02765	COG4565	transcriptional regulatory protein
AXW78_RS02770	COG2851	Citrate transporter
AXW78_RS02795	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AXW78_RS02800	COG3842	ATPase activity
AXW78_RS02805	COG1175	transmembrane transport
AXW78_RS02810	COG0395	ABC-type sugar transport system, permease component
AXW78_RS02820	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AXW78_RS02825	COG0745	RESPONSE REGULATOR receiver
AXW78_RS02830	COG5002	protein histidine kinase activity
AXW78_RS02840	COG4990	cell redox homeostasis
AXW78_RS02850	COG3290	protein histidine kinase activity
AXW78_RS02855	COG4565	transcriptional regulatory protein
AXW78_RS02860	COG3493	citrate carrier protein
AXW78_RS02865	COG0281	malic enzyme
AXW78_RS02875	COG0697	spore germination
AXW78_RS02880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW78_RS02890	COG5002	protein histidine kinase activity
AXW78_RS02910	COG0456	acetyltransferase
AXW78_RS02910	COG0454	-acetyltransferase
AXW78_RS02915	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AXW78_RS02920	COG3383	formate dehydrogenase (NAD+) activity
AXW78_RS02925	COG2427	Protein of unknown function (DUF1641)
AXW78_RS02940	COG0531	amino acid
AXW78_RS02945	COG0640	Transcriptional regulator
AXW78_RS02950	COG2217	Heavy metal translocating P-type atpase
AXW78_RS02955	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AXW78_RS02965	COG3227	Zinc metalloprotease (Elastase)
AXW78_RS02985	COG2720	vancomycin resistance protein
AXW78_RS02990	COG1316	TRANSCRIPTIONal
AXW78_RS02995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXW78_RS03000	COG0346	lactoylglutathione lyase activity
AXW78_RS03005	COG1253	flavin adenine dinucleotide binding
AXW78_RS03010	COG1027	Aspartate ammonia-lyase
AXW78_RS03015	COG1620	l-lactate permease
AXW78_RS03030	COG3104	oligopeptide transport
AXW78_RS03035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXW78_RS03040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW78_RS03045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW78_RS03060	COG0156	8-amino-7-oxononanoate synthase activity
AXW78_RS03065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXW78_RS03075	COG4548	von Willebrand factor, type A
AXW78_RS03080	COG0714	Associated with various cellular activities
AXW78_RS03100	COG0531	amino acid
AXW78_RS03105	COG2188	Transcriptional regulator
AXW78_RS03110	COG1263	PTS System
AXW78_RS03110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXW78_RS03115	COG0366	Alpha amylase catalytic
AXW78_RS03130	COG0697	spore germination
AXW78_RS03135	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AXW78_RS03140	COG1115	amino acid carrier protein
AXW78_RS03150	COG1126	abc transporter atp-binding protein
AXW78_RS03155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW78_RS03160	COG0765	amino acid transport
AXW78_RS03165	COG0765	amino acid transport
AXW78_RS03170	COG0833	amino acid
AXW78_RS03185	COG1595	DNA-templated transcription, initiation
AXW78_RS03195	COG2378	regulation of single-species biofilm formation
AXW78_RS03200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AXW78_RS03205	COG5002	protein histidine kinase activity
AXW78_RS03220	COG0659	secondary active sulfate transmembrane transporter activity
AXW78_RS03235	COG2271	Major facilitator Superfamily
AXW78_RS03240	COG1846	Transcriptional regulator
AXW78_RS03245	COG0477	Major facilitator Superfamily
AXW78_RS03250	COG1609	Transcriptional regulator
AXW78_RS03255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW78_RS03270	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW78_RS03275	COG1879	ABC-type sugar transport system periplasmic component
AXW78_RS03300	COG1063	alcohol dehydrogenase
AXW78_RS03350	COG0840	transmembrane signaling receptor activity
AXW78_RS03355	COG3584	3D domain protein
AXW78_RS03355	COG3583	domain protein
AXW78_RS03360	COG1476	TRANSCRIPTIONal
AXW78_RS03380	COG3104	oligopeptide transport
AXW78_RS03385	COG1114	Component of the transport system for branched-chain amino acids
AXW78_RS03400	COG1113	amino acid transport
AXW78_RS03405	COG2252	PERMEase
AXW78_RS03420	COG2153	protein acetylation
AXW78_RS03430	COG0475	glutathione-regulated potassium exporter activity
AXW78_RS03430	COG0569	domain protein
AXW78_RS03445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXW78_RS03450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AXW78_RS03455	COG0833	amino acid
AXW78_RS03460	COG4990	cell redox homeostasis
AXW78_RS03475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXW78_RS03480	COG0697	spore germination
AXW78_RS03485	COG0531	amino acid
AXW78_RS03495	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AXW78_RS03500	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AXW78_RS03505	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AXW78_RS03505	COG1918	ferrous iron import across plasma membrane
AXW78_RS03510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXW78_RS03515	COG0573	inorganic phosphate transmembrane transporter activity
AXW78_RS03520	COG0581	inorganic phosphate transmembrane transporter activity
AXW78_RS03530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXW78_RS03650	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AXW78_RS03670	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXW78_RS03675	COG1116	anion transmembrane transporter activity
AXW78_RS03680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW78_RS03685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW78_RS03690	COG0352	thiamine-phosphate diphosphorylase activity
AXW78_RS03695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW78_RS03700	COG2104	thiamine diphosphate biosynthetic process
AXW78_RS03710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXW78_RS03715	COG0351	phosphomethylpyrimidine kinase
AXW78_RS03735	COG1136	(ABC) transporter
AXW78_RS03780	COG2205	protein histidine kinase activity
AXW78_RS03785	COG2814	Major facilitator Superfamily
AXW78_RS03790	COG1846	Transcriptional regulator
AXW78_RS03805	COG2252	PERMEase
AXW78_RS03810	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS03825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXW78_RS03830	COG1621	beta-fructofuranosidase activity
AXW78_RS03835	COG1263	PTS System
AXW78_RS03835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXW78_RS03840	COG1609	Transcriptional regulator
AXW78_RS03890	COG0778	Nitroreductase
AXW78_RS03895	COG2719	SpoVR family
AXW78_RS03905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXW78_RS03910	COG1937	Protein conserved in bacteria
AXW78_RS03915	COG0425	Belongs to the sulfur carrier protein TusA family
AXW78_RS03915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXW78_RS03920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXW78_RS03920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW78_RS03925	COG0425	Belongs to the sulfur carrier protein TusA family
AXW78_RS03930	COG0425	Belongs to the sulfur carrier protein TusA family
AXW78_RS03930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXW78_RS03935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXW78_RS03940	COG2210	Belongs to the sulfur carrier protein TusA family
AXW78_RS03945	COG0730	response to heat
AXW78_RS03955	COG1316	TRANSCRIPTIONal
AXW78_RS03960	COG0604	alcohol dehydrogenase
AXW78_RS03965	COG1283	sodium-dependent phosphate transmembrane transporter activity
AXW78_RS03980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXW78_RS03980	COG3711	transcriptional antiterminator
AXW78_RS03985	COG1447	Phosphotransferase system cellobiose-specific component IIA
AXW78_RS03990	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXW78_RS04015	COG3584	3D domain protein
AXW78_RS04015	COG1388	LysM domain
AXW78_RS04020	COG0577	efflux transmembrane transporter activity
AXW78_RS04025	COG1136	(ABC) transporter
AXW78_RS04035	COG5522	Integral membrane protein (intg_mem_TP0381)
AXW78_RS04050	COG1114	Component of the transport system for branched-chain amino acids
AXW78_RS04055	COG3546	catalase activity
AXW78_RS04090	COG0586	Pfam SNARE associated Golgi protein
AXW78_RS04120	COG0531	amino acid
AXW78_RS04125	COG0475	glutathione-regulated potassium exporter activity
AXW78_RS04135	COG1737	Transcriptional regulator
AXW78_RS04145	COG1263	PTS System
AXW78_RS04145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXW78_RS04155	COG2259	Doxx family
AXW78_RS04175	COG1522	sequence-specific DNA binding
AXW78_RS04190	COG2076	Multidrug Resistance protein
AXW78_RS04195	COG1309	transcriptional regulator
AXW78_RS04200	COG2814	Major facilitator Superfamily
AXW78_RS04205	COG4533	DNA binding
AXW78_RS04210	COG2814	Major facilitator Superfamily
AXW78_RS04220	COG0693	protein deglycase activity
AXW78_RS04225	COG0753	catalase activity
AXW78_RS04235	COG0531	amino acid
AXW78_RS04250	COG1012	belongs to the aldehyde dehydrogenase family
AXW78_RS04255	COG1132	(ABC) transporter
AXW78_RS04260	COG1132	(ABC) transporter
AXW78_RS04265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW78_RS04270	COG0765	amino acid transport
AXW78_RS04275	COG1126	abc transporter atp-binding protein
AXW78_RS04290	COG0189	ligase activity
AXW78_RS04320	COG0028	Belongs to the TPP enzyme family
AXW78_RS04325	COG3527	Alpha-acetolactate decarboxylase
AXW78_RS04335	COG0561	phosphatase activity
AXW78_RS04350	COG5632	N-Acetylmuramoyl-L-alanine amidase
AXW78_RS04350	COG3409	Peptidoglycan-binding domain 1 protein
AXW78_RS04355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXW78_RS04360	COG0318	PFAM AMP-dependent synthetase and ligase
AXW78_RS04375	COG0659	secondary active sulfate transmembrane transporter activity
AXW78_RS04380	COG2244	polysaccharide biosynthetic process
AXW78_RS04400	COG1024	Enoyl-CoA hydratase
AXW78_RS04420	COG1363	Peptidase, m42
AXW78_RS04460	COG0601	transmembrane transport
AXW78_RS04465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW78_RS04470	COG0444	Belongs to the ABC transporter superfamily
AXW78_RS04475	COG4608	Belongs to the ABC transporter superfamily
AXW78_RS04485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW78_RS04585	COG0582	viral genome integration into host DNA
AXW78_RS04590	COG0477	Major facilitator Superfamily
AXW78_RS04595	COG3290	protein histidine kinase activity
AXW78_RS04600	COG4565	transcriptional regulatory protein
AXW78_RS04605	COG3181	Tripartite tricarboxylate transporter family receptor
AXW78_RS04640	COG0789	Transcriptional regulator
AXW78_RS04640	COG4978	Transcriptional regulator
AXW78_RS04655	COG0305	Participates in initiation and elongation during chromosome replication
AXW78_RS04675	COG0477	Major facilitator Superfamily
AXW78_RS04690	COG2801	Transposase and inactivated derivatives
AXW78_RS04715	COG1073	alpha beta
AXW78_RS04760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXW78_RS04760	COG3320	Male sterility
AXW78_RS04765	COG1309	transcriptional regulator
AXW78_RS04780	COG1183	phosphatidylcholine synthase activity
AXW78_RS04795	COG2376	Dihydroxyacetone kinase
AXW78_RS04805	COG2376	Dihydroxyacetone kinase
AXW78_RS04850	COG2373	Large extracellular alpha-helical protein
AXW78_RS04870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXW78_RS04965	COG1191	sigma factor activity
AXW78_RS04975	COG2208	phosphoserine phosphatase activity
AXW78_RS04980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AXW78_RS04985	COG2205	protein histidine kinase activity
AXW78_RS04985	COG0784	Response regulator, receiver
AXW78_RS04985	COG5002	protein histidine kinase activity
AXW78_RS05030	COG4585	Histidine kinase
AXW78_RS05035	COG2197	response regulator
AXW78_RS05060	COG0420	3'-5' exonuclease activity
AXW78_RS05065	COG4717	serine-type aminopeptidase activity
AXW78_RS05075	COG0346	lactoylglutathione lyase activity
AXW78_RS05080	COG0346	lactoylglutathione lyase activity
AXW78_RS05085	COG0457	Tetratricopeptide repeat
AXW78_RS05095	COG2267	carboxylic ester hydrolase activity
AXW78_RS05115	COG2140	Oxalate decarboxylase
AXW78_RS05120	COG3620	sequence-specific DNA binding
AXW78_RS05125	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AXW78_RS05130	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AXW78_RS05140	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AXW78_RS05150	COG1595	DNA-templated transcription, initiation
AXW78_RS05165	COG3973	AAA domain
AXW78_RS05195	COG4980	gas vesicle protein
AXW78_RS05200	COG0537	adenosine 5'-monophosphoramidase activity
AXW78_RS05205	COG1131	(ABC) transporter
AXW78_RS05210	COG4473	ABC transporter
AXW78_RS05220	COG1309	transcriptional regulator
AXW78_RS05230	COG3402	PFAM membrane-flanked domain
AXW78_RS05235	COG3428	Bacterial PH domain
AXW78_RS05270	COG0697	spore germination
AXW78_RS05275	COG3402	PFAM membrane-flanked domain
AXW78_RS05280	COG3428	Bacterial PH domain
AXW78_RS05285	COG2329	Antibiotic biosynthesis monooxygenase
AXW78_RS05290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXW78_RS05305	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AXW78_RS05340	COG1309	transcriptional regulator
AXW78_RS05345	COG1511	domain protein
AXW78_RS05365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW78_RS05370	COG1609	Transcriptional regulator
AXW78_RS05380	COG1234	tRNA 3'-trailer cleavage
AXW78_RS05385	COG0095	Lipoate-protein ligase
AXW78_RS05395	COG0318	PFAM AMP-dependent synthetase and ligase
AXW78_RS05415	COG1408	metallophosphoesterase
AXW78_RS05420	COG1078	dGTPase activity
AXW78_RS05430	COG1595	DNA-templated transcription, initiation
AXW78_RS05435	COG3708	Transcriptional regulator
AXW78_RS05435	COG2207	Transcriptional regulator
AXW78_RS05440	COG2205	protein histidine kinase activity
AXW78_RS05445	COG0745	RESPONSE REGULATOR receiver
AXW78_RS05465	COG0501	Belongs to the peptidase M48B family
AXW78_RS05470	COG0840	transmembrane signaling receptor activity
AXW78_RS05475	COG3693	PFAM glycoside hydrolase, family 10
AXW78_RS05485	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AXW78_RS05490	COG2224	Isocitrate lyase
AXW78_RS05505	COG1278	Cold shock
AXW78_RS05525	COG0398	Pfam SNARE associated Golgi protein
AXW78_RS05545	COG0202	RNA polymerase activity
AXW78_RS05585	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXW78_RS05610	COG0367	asparagine synthase
AXW78_RS05620	COG0753	catalase activity
AXW78_RS05625	COG0004	ammonium transporteR
AXW78_RS05645	COG2996	Protein conserved in bacteria
AXW78_RS05655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXW78_RS05670	COG0561	phosphatase activity
AXW78_RS05690	COG2267	carboxylic ester hydrolase activity
AXW78_RS05710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXW78_RS05715	COG5504	Zn-dependent protease
AXW78_RS05725	COG0180	Tryptophanyl-tRNA synthetase
AXW78_RS05735	COG4166	transmembrane transport
AXW78_RS05740	COG0601	transmembrane transport
AXW78_RS05745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXW78_RS05750	COG0444	Belongs to the ABC transporter superfamily
AXW78_RS05755	COG4608	Belongs to the ABC transporter superfamily
AXW78_RS05760	COG0534	Mate efflux family protein
AXW78_RS05765	COG4166	transmembrane transport
AXW78_RS05780	COG0861	Integral membrane protein TerC family
AXW78_RS05790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXW78_RS05800	COG1164	Oligoendopeptidase f
AXW78_RS05810	COG2346	COG2346, Truncated hemoglobins
AXW78_RS05815	COG4116	CYTH
AXW78_RS05825	COG2357	RelA SpoT domain protein
AXW78_RS05835	COG0564	pseudouridine synthase activity
AXW78_RS05855	COG1216	Glycosyl transferase, family 2
AXW78_RS05885	COG0457	Tetratricopeptide repeat
AXW78_RS05885	COG0463	Glycosyl transferase, family 2
AXW78_RS05905	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AXW78_RS05920	COG1091	dTDP-4-dehydrorhamnose reductase activity
AXW78_RS05965	COG2153	protein acetylation
AXW78_RS05975	COG2382	esterase
AXW78_RS05995	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXW78_RS06010	COG0512	Glutamine amidotransferase of anthranilate synthase
AXW78_RS06010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AXW78_RS06045	COG1620	l-lactate permease
AXW78_RS06055	COG5634	Uncharacterized conserved protein (DUF2278)
AXW78_RS06105	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXW78_RS06115	COG1476	TRANSCRIPTIONal
AXW78_RS06165	COG1686	Belongs to the peptidase S11 family
AXW78_RS06170	COG0681	Belongs to the peptidase S26 family
AXW78_RS06205	COG1012	belongs to the aldehyde dehydrogenase family
AXW78_RS06215	COG1176	ABC-type spermidine putrescine transport system, permease component I
AXW78_RS06220	COG1177	transmembrane transport
AXW78_RS06235	COG2409	Drug exporters of the RND superfamily
AXW78_RS06245	COG0564	pseudouridine synthase activity
AXW78_RS06255	COG2340	Cysteine-rich secretory protein family
AXW78_RS06260	COG0247	lactate metabolic process
AXW78_RS06265	COG0277	FAD linked oxidase domain protein
AXW78_RS06270	COG3835	regulator
AXW78_RS06280	COG0745	RESPONSE REGULATOR receiver
AXW78_RS06285	COG5002	protein histidine kinase activity
AXW78_RS06290	COG2186	Transcriptional regulator
AXW78_RS06310	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AXW78_RS06320	COG2116	formate transmembrane transporter activity
AXW78_RS06325	COG0861	Integral membrane protein TerC family
AXW78_RS06330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXW78_RS06340	COG2030	dehydratase
AXW78_RS06360	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS06365	COG3243	poly(R)-hydroxyalkanoic acid synthase
AXW78_RS06375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXW78_RS06390	COG1840	ABC-type Fe3 transport system, periplasmic component
AXW78_RS06395	COG3842	ATPase activity
AXW78_RS06420	COG1349	DNA-binding transcription factor activity
AXW78_RS06435	COG0235	Class ii aldolase
AXW78_RS06445	COG2861	carbohydrate metabolic process
AXW78_RS06455	COG3852	Histidine kinase
AXW78_RS06460	COG1846	Transcriptional regulator
AXW78_RS06470	COG2318	DinB family
AXW78_RS06480	COG5002	protein histidine kinase activity
AXW78_RS06490	COG0720	synthase
AXW78_RS06505	COG4873	Protein conserved in bacteria
AXW78_RS06535	COG1780	Probably involved in ribonucleotide reductase function
AXW78_RS06540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXW78_RS06545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXW78_RS06550	COG1725	Transcriptional regulator
AXW78_RS06555	COG1131	(ABC) transporter
AXW78_RS06565	COG1131	(ABC) transporter
AXW78_RS06570	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AXW78_RS06585	COG1522	sequence-specific DNA binding
AXW78_RS06595	COG1335	isochorismatase
AXW78_RS06605	COG1619	proteins homologs of microcin C7 resistance protein MccF
AXW78_RS06610	COG2070	2-Nitropropane dioxygenase
AXW78_RS06615	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AXW78_RS06625	COG1696	Membrane protein involved in D-alanine export
AXW78_RS06650	COG0716	FMN binding
AXW78_RS06710	COG1846	Transcriptional regulator
AXW78_RS06720	COG1301	dicarboxylic acid transport
AXW78_RS06725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXW78_RS06730	COG4709	membrane
AXW78_RS06735	COG3874	Sporulation protein YtfJ
AXW78_RS06755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXW78_RS06760	COG0028	Belongs to the TPP enzyme family
AXW78_RS06765	COG0440	acetolactate synthase activity
AXW78_RS06840	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AXW78_RS06855	COG1183	phosphatidylcholine synthase activity
AXW78_RS06860	COG1368	sulfuric ester hydrolase activity
AXW78_RS06870	COG0019	diaminopimelate decarboxylase activity
AXW78_RS06890	COG0529	Catalyzes the synthesis of activated sulfate
AXW78_RS06895	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXW78_RS06915	COG1648	precorrin-2 dehydrogenase activity
AXW78_RS06920	COG0733	neurotransmitter:sodium symporter activity
AXW78_RS06940	COG1757	Na H antiporter
AXW78_RS06955	COG4758	membrane
AXW78_RS06960	COG4585	Histidine kinase
AXW78_RS06965	COG2197	response regulator
AXW78_RS06975	COG1114	Component of the transport system for branched-chain amino acids
AXW78_RS06985	COG2226	methyltransferase
AXW78_RS07025	COG0730	response to heat
AXW78_RS07030	COG0306	phosphate transporter
AXW78_RS07035	COG1392	Phosphate transport regulator
AXW78_RS07040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXW78_RS07055	COG3852	Histidine kinase
AXW78_RS07060	COG1801	Protein of unknown function DUF72
AXW78_RS07070	COG0582	viral genome integration into host DNA
AXW78_RS07075	COG5002	protein histidine kinase activity
AXW78_RS07090	COG0392	lysyltransferase activity
AXW78_RS07090	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AXW78_RS07105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXW78_RS07110	COG1686	Belongs to the peptidase S11 family
AXW78_RS07115	COG2715	membrane protein required for spore maturation
AXW78_RS07120	COG0700	Nucleoside recognition
AXW78_RS07125	COG1187	pseudouridine synthase activity
AXW78_RS07135	COG1333	cytochrome c biogenesis protein
AXW78_RS07140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXW78_RS07145	COG0745	RESPONSE REGULATOR receiver
AXW78_RS07150	COG5002	protein histidine kinase activity
AXW78_RS07170	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AXW78_RS07175	COG1141	Ferredoxin
AXW78_RS07185	COG0514	ATP-dependent DNA helicase (RecQ)
AXW78_RS07190	COG1266	CAAX protease self-immunity
AXW78_RS07200	COG1408	metallophosphoesterase
AXW78_RS07205	COG0789	Transcriptional regulator
AXW78_RS07215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXW78_RS07235	COG0492	ferredoxin-NADP+ reductase activity
AXW78_RS07240	COG0252	asparaginase activity
AXW78_RS07305	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AXW78_RS07320	COG0142	geranyltranstransferase activity
AXW78_RS07330	COG0142	geranyltranstransferase activity
AXW78_RS07355	COG0457	Tetratricopeptide repeat
AXW78_RS07375	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AXW78_RS07380	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AXW78_RS07380	COG2010	Cytochrome c
AXW78_RS07385	COG4347	Protein of unknown function (DUF1405)
AXW78_RS07400	COG2738	Putative neutral zinc metallopeptidase
AXW78_RS07410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXW78_RS07415	COG1694	Mazg nucleotide pyrophosphohydrolase
AXW78_RS07435	COG0438	transferase activity, transferring glycosyl groups
AXW78_RS07465	COG1199	ATP-dependent helicase activity
AXW78_RS07465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXW78_RS07485	COG3935	DnaD domain protein
AXW78_RS07490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AXW78_RS07500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXW78_RS07500	COG4499	WXG100 protein secretion system (Wss), protein YukC
AXW78_RS07555	COG0116	Belongs to the methyltransferase superfamily
AXW78_RS07565	COG1199	ATP-dependent helicase activity
AXW78_RS07570	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AXW78_RS07580	COG0024	Methionine aminopeptidase
AXW78_RS07590	COG2233	PERMEase
AXW78_RS07595	COG2311	Membrane
AXW78_RS07600	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AXW78_RS07610	COG0456	acetyltransferase
AXW78_RS07620	COG2897	thiosulfate sulfurtransferase activity
AXW78_RS07645	COG0754	glutathionylspermidine amidase activity
AXW78_RS07660	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXW78_RS07675	COG3944	biosynthesis protein
AXW78_RS07685	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AXW78_RS07700	COG1215	transferase activity, transferring glycosyl groups
AXW78_RS07705	COG0438	transferase activity, transferring glycosyl groups
AXW78_RS07740	COG0328	RNA-DNA hybrid ribonuclease activity
AXW78_RS07775	COG3403	YqcI/YcgG family
AXW78_RS07780	COG1280	lysine exporter protein (LysE YggA)
AXW78_RS07795	COG3162	membrane
AXW78_RS07800	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXW78_RS07805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXW78_RS07815	COG0475	glutathione-regulated potassium exporter activity
AXW78_RS07820	COG0789	Transcriptional regulator
AXW78_RS07820	COG4978	Transcriptional regulator
AXW78_RS07830	COG2323	membrane
AXW78_RS07835	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AXW78_RS07865	COG1923	regulation of RNA biosynthetic process
AXW78_RS07875	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AXW78_RS07880	COG1360	Flagellar Motor Protein
AXW78_RS07885	COG2201	protein-glutamate methylesterase activity
AXW78_RS07890	COG2198	Histidine kinase
AXW78_RS07890	COG0643	Histidine kinase
AXW78_RS07895	COG1776	CheC inhibitor of MCP methylation
AXW78_RS07895	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW78_RS07910	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AXW78_RS07930	COG1256	bacterial-type flagellum assembly
AXW78_RS07935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXW78_RS07955	COG1815	bacterial-type flagellum-dependent cell motility
AXW78_RS07960	COG1558	bacterial-type flagellum-dependent cell motility
AXW78_RS07970	COG1766	The M ring may be actively involved in energy transduction
AXW78_RS07975	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW78_RS07985	COG1157	protein secretion by the type III secretion system
AXW78_RS08020	COG0835	chemotaxis
AXW78_RS08020	COG0784	Response regulator, receiver
AXW78_RS08035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXW78_RS08040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXW78_RS08045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AXW78_RS08050	COG0741	lytic transglycosylase activity
AXW78_RS08060	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW78_RS08065	COG1776	CheC inhibitor of MCP methylation
AXW78_RS08065	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AXW78_RS08075	COG1338	Plays a role in the flagellum-specific transport system
AXW78_RS08080	COG1987	bacterial-type flagellum assembly
AXW78_RS08090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXW78_RS08095	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AXW78_RS08100	COG1419	protein localization to endoplasmic reticulum
AXW78_RS08110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AXW78_RS08140	COG2329	Antibiotic biosynthesis monooxygenase
AXW78_RS08145	COG1215	transferase activity, transferring glycosyl groups
AXW78_RS08170	COG0583	DNA-binding transcription factor activity
AXW78_RS08215	COG0406	alpha-ribazole phosphatase activity
AXW78_RS08245	COG0367	asparagine synthase
AXW78_RS08275	COG1802	Transcriptional regulator
AXW78_RS08280	COG0697	spore germination
AXW78_RS08285	COG0523	cobalamin synthesis protein
AXW78_RS08290	COG0701	Predicted permease
AXW78_RS08305	COG1757	Na H antiporter
AXW78_RS08310	COG0789	Transcriptional regulator
AXW78_RS08335	COG0534	Mate efflux family protein
AXW78_RS08340	COG3340	Belongs to the peptidase S51 family
AXW78_RS08380	COG2733	membrane
AXW78_RS08415	COG1131	(ABC) transporter
AXW78_RS08430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXW78_RS08435	COG0528	UMP kinase activity
AXW78_RS08445	COG1027	Aspartate ammonia-lyase
AXW78_RS08450	COG0281	malic enzyme
AXW78_RS08455	COG4191	Histidine kinase
AXW78_RS08460	COG0784	Response regulator, receiver
AXW78_RS08465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AXW78_RS08515	COG2814	Major facilitator Superfamily
AXW78_RS08535	COG1695	Transcriptional regulator
AXW78_RS08550	COG0477	Major facilitator Superfamily
AXW78_RS08560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXW78_RS08565	COG2223	nitrite transmembrane transporter activity
AXW78_RS08570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AXW78_RS08590	COG0733	neurotransmitter:sodium symporter activity
AXW78_RS08600	COG5566	PFAM Mor transcription activator
AXW78_RS08605	COG2323	membrane
AXW78_RS08630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW78_RS08640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXW78_RS08645	COG0028	Belongs to the TPP enzyme family
AXW78_RS08665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXW78_RS08690	COG2814	Major facilitator Superfamily
AXW78_RS08695	COG3384	dioxygenase
AXW78_RS08705	COG3279	Response regulator of the LytR AlgR family
AXW78_RS08710	COG0427	acetyl-CoA hydrolase
AXW78_RS08730	COG4166	transmembrane transport
AXW78_RS08735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW78_RS08755	COG1914	H( )-stimulated, divalent metal cation uptake system
AXW78_RS08770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXW78_RS08780	COG0531	amino acid
AXW78_RS08815	COG1309	transcriptional regulator
AXW78_RS08820	COG2390	Transcriptional regulator
AXW78_RS08830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXW78_RS08835	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AXW78_RS08855	COG0006	proline dipeptidase activity
AXW78_RS08865	COG2132	Multicopper oxidase
AXW78_RS08875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXW78_RS08895	COG1114	Component of the transport system for branched-chain amino acids
AXW78_RS08905	COG2372	response to copper ion
AXW78_RS08905	COG1276	copper resistance
AXW78_RS08910	COG4549	nuclear export factor GLE1
AXW78_RS08915	COG0697	spore germination
AXW78_RS08920	COG0583	DNA-binding transcription factor activity
AXW78_RS08925	COG1959	2 iron, 2 sulfur cluster binding
AXW78_RS08930	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AXW78_RS08935	COG0778	Nitroreductase
AXW78_RS08945	COG0154	amidase activity
AXW78_RS08950	COG1396	sequence-specific DNA binding
AXW78_RS09035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXW78_RS09035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXW78_RS09115	COG2002	toxin-antitoxin pair type II binding
AXW78_RS09130	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXW78_RS09130	COG0515	serine threonine protein kinase
AXW78_RS09150	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW78_RS09260	COG3409	Peptidoglycan-binding domain 1 protein
AXW78_RS09260	COG1388	LysM domain
AXW78_RS09260	COG5632	N-Acetylmuramoyl-L-alanine amidase
AXW78_RS09270	COG2801	Transposase and inactivated derivatives
AXW78_RS09285	COG0717	Belongs to the dCTP deaminase family
AXW78_RS09340	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXW78_RS09350	COG0628	permease
AXW78_RS09360	COG1231	oxidoreductase activity
AXW78_RS09365	COG0523	cobalamin synthesis protein
AXW78_RS09375	COG0411	ABC transporter
AXW78_RS09395	COG0583	DNA-binding transcription factor activity
AXW78_RS09415	COG1846	Transcriptional regulator
AXW78_RS09425	COG1271	oxidase subunit
AXW78_RS09430	COG1294	oxidase, subunit
AXW78_RS09435	COG4988	ABC transporter
AXW78_RS09440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AXW78_RS09450	COG1216	Glycosyl transferase, family 2
AXW78_RS09490	COG1686	Belongs to the peptidase S11 family
AXW78_RS09505	COG1388	LysM domain
AXW78_RS09505	COG0791	NLP P60 protein
AXW78_RS09515	COG1132	(ABC) transporter
AXW78_RS09520	COG0745	RESPONSE REGULATOR receiver
AXW78_RS09525	COG5002	protein histidine kinase activity
AXW78_RS09530	COG0300	oxidoreductase activity
AXW78_RS09550	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AXW78_RS09560	COG0460	homoserine dehydrogenase
AXW78_RS09585	COG1316	TRANSCRIPTIONal
AXW78_RS09595	COG0745	RESPONSE REGULATOR receiver
AXW78_RS09600	COG5002	protein histidine kinase activity
AXW78_RS09615	COG1285	pathogenesis
AXW78_RS09620	COG1247	-acetyltransferase
AXW78_RS09640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXW78_RS09650	COG1082	Xylose isomerase domain protein TIM barrel
AXW78_RS09660	COG2814	Major facilitator Superfamily
AXW78_RS09665	COG1279	arginine transmembrane transporter activity
AXW78_RS09670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW78_RS09680	COG1752	Esterase of the alpha-beta hydrolase superfamily
AXW78_RS09715	COG0577	efflux transmembrane transporter activity
AXW78_RS09720	COG2002	toxin-antitoxin pair type II binding
AXW78_RS09725	COG1404	Belongs to the peptidase S8 family
AXW78_RS09730	COG0640	Transcriptional regulator
AXW78_RS09735	COG0667	Aldo Keto reductase
AXW78_RS09740	COG2814	Major facilitator Superfamily
AXW78_RS09750	COG3152	Membrane
AXW78_RS09775	COG0840	transmembrane signaling receptor activity
AXW78_RS09790	COG3949	Membrane
AXW78_RS09795	COG0783	Belongs to the Dps family
AXW78_RS09810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXW78_RS09820	COG1231	oxidoreductase activity
AXW78_RS09825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW78_RS09830	COG4989	oxidoreductase activity
AXW78_RS09835	COG0523	cobalamin synthesis protein
AXW78_RS09840	COG0456	acetyltransferase
AXW78_RS09845	COG0803	Belongs to the bacterial solute-binding protein 9 family
AXW78_RS09850	COG0702	epimerase
AXW78_RS09860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXW78_RS09895	COG5337	Spore coat protein CotH
AXW78_RS09900	COG1051	belongs to the nudix hydrolase family
AXW78_RS09905	COG0586	Pfam SNARE associated Golgi protein
AXW78_RS09910	COG2244	polysaccharide biosynthetic process
AXW78_RS09920	COG0701	Predicted permease
AXW78_RS09925	COG3689	TIGRFAM TIGR03943 family protein
AXW78_RS09930	COG1607	acyl-coa hydrolase
AXW78_RS09935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXW78_RS09950	COG0702	epimerase
AXW78_RS09955	COG2839	Protein conserved in bacteria
AXW78_RS09960	COG1253	flavin adenine dinucleotide binding
AXW78_RS09990	COG1114	Component of the transport system for branched-chain amino acids
AXW78_RS09995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXW78_RS10010	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXW78_RS10020	COG1876	peptidase activity
AXW78_RS10035	COG2211	Major facilitator Superfamily
AXW78_RS10050	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXW78_RS10060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AXW78_RS10070	COG1819	glycosyl
AXW78_RS10075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXW78_RS10080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW78_RS10110	COG0456	acetyltransferase
AXW78_RS10155	COG4499	WXG100 protein secretion system (Wss), protein YukC
AXW78_RS10250	COG3874	Sporulation protein YtfJ
AXW78_RS10275	COG2226	methyltransferase
AXW78_RS10295	COG1082	Xylose isomerase domain protein TIM barrel
AXW78_RS10300	COG0346	lactoylglutathione lyase activity
AXW78_RS10310	COG0604	alcohol dehydrogenase
AXW78_RS10315	COG1595	DNA-templated transcription, initiation
AXW78_RS10330	COG0426	domain, Protein
AXW78_RS10330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXW78_RS10340	COG0386	Belongs to the glutathione peroxidase family
AXW78_RS10345	COG1305	Transglutaminase-like
AXW78_RS10350	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AXW78_RS10355	COG0714	Associated with various cellular activities
AXW78_RS10360	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AXW78_RS10365	COG1140	nitrate reductase beta subunit
AXW78_RS10370	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AXW78_RS10375	COG2181	nitrate reductase activity
AXW78_RS10380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW78_RS10385	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AXW78_RS10390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXW78_RS10395	COG0303	'Molybdopterin
AXW78_RS10400	COG0314	molybdopterin synthase activity
AXW78_RS10410	COG2223	nitrite transmembrane transporter activity
AXW78_RS10425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AXW78_RS10425	COG1648	precorrin-2 dehydrogenase activity
AXW78_RS10435	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AXW78_RS10435	COG1587	Uroporphyrinogen-III synthase
AXW78_RS10440	COG2146	nitrite reductase [NAD(P)H] activity
AXW78_RS10445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXW78_RS10450	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AXW78_RS10470	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AXW78_RS10485	COG2359	stage V sporulation protein S
AXW78_RS10500	COG0457	Tetratricopeptide repeat
AXW78_RS10515	COG1418	mRNA catabolic process
AXW78_RS10520	COG0488	(ABC) transporter
AXW78_RS10535	COG0629	single-stranded DNA binding
AXW78_RS10545	COG1413	lyase activity
AXW78_RS10560	COG2521	methyltransferase
AXW78_RS10560	COG2136	Putative SAM-dependent methyltransferase
AXW78_RS10565	COG0018	arginyl-trna synthetase
AXW78_RS10610	COG0017	Asparaginyl-tRNA synthetase
AXW78_RS10615	COG0733	neurotransmitter:sodium symporter activity
AXW78_RS10640	COG2610	gluconate transmembrane transporter activity
AXW78_RS10660	COG0456	acetyltransferase
AXW78_RS10665	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AXW78_RS10680	COG0546	phosphoglycolate phosphatase activity
AXW78_RS10695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXW78_RS10710	COG0768	penicillin binding
AXW78_RS10720	COG0204	Acyl-transferase
AXW78_RS10725	COG1272	protein, Hemolysin III
AXW78_RS10735	COG0805	protein transport
AXW78_RS10745	COG1307	EDD domain protein, DegV family
AXW78_RS10755	COG1999	signal sequence binding
AXW78_RS10760	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW78_RS10765	COG0367	asparagine synthase
AXW78_RS10780	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXW78_RS10785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXW78_RS10790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXW78_RS10805	COG1335	isochorismatase
AXW78_RS10810	COG0071	Belongs to the small heat shock protein (HSP20) family
AXW78_RS10815	COG0668	transmembrane transport
AXW78_RS10820	COG2203	Gaf domain
AXW78_RS10820	COG4585	Histidine kinase
AXW78_RS10825	COG2197	response regulator
AXW78_RS10830	COG1737	Transcriptional regulator
AXW78_RS10835	COG0384	phenazine biosynthesis protein PhzF
AXW78_RS10840	COG1064	alcohol dehydrogenase
AXW78_RS10865	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AXW78_RS10900	COG1125	glycine betaine transport
AXW78_RS10900	COG0517	IMP dehydrogenase activity
AXW78_RS10905	COG1174	glycine betaine transport
AXW78_RS10940	COG1253	flavin adenine dinucleotide binding
AXW78_RS10945	COG1012	belongs to the aldehyde dehydrogenase family
AXW78_RS10950	COG5506	Protein of unknown function (DUF1694)
AXW78_RS10965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXW78_RS10970	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AXW78_RS10975	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXW78_RS10980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXW78_RS10985	COG0456	acetyltransferase
AXW78_RS10990	COG3829	transcription factor binding
AXW78_RS10995	COG1509	lysine 2,3-aminomutase activity
AXW78_RS11025	COG0515	serine threonine protein kinase
AXW78_RS11025	COG3064	Membrane
AXW78_RS11025	COG4991	sh3 domain protein
AXW78_RS11035	COG0671	phosphoesterase, PA-phosphatase related
AXW78_RS11040	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AXW78_RS11045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXW78_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS11155	COG4499	WXG100 protein secretion system (Wss), protein YukC
AXW78_RS11155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXW78_RS11165	COG2814	Major facilitator Superfamily
AXW78_RS11170	COG4841	protein insertion into membrane
AXW78_RS11175	COG0372	Belongs to the citrate synthase family
AXW78_RS11180	COG2079	MmgE PrpD family protein
AXW78_RS11185	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AXW78_RS11190	COG1960	acyl-CoA dehydrogenase activity
AXW78_RS11195	COG2084	Dehydrogenase
AXW78_RS11205	COG1280	lysine exporter protein (LysE YggA)
AXW78_RS11210	COG1024	Enoyl-CoA hydratase
AXW78_RS11225	COG0420	3'-5' exonuclease activity
AXW78_RS11230	COG0419	ATPase involved in DNA repair
AXW78_RS11250	COG2223	nitrite transmembrane transporter activity
AXW78_RS11255	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS11260	COG1169	isochorismate synthase
AXW78_RS11265	COG1021	2,3-dihydroxybenzoate-AMP ligase
AXW78_RS11270	COG3433	isochorismatase activity
AXW78_RS11270	COG1535	isochorismatase
AXW78_RS11275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXW78_RS11280	COG3251	PFAM MbtH domain protein
AXW78_RS11285	COG2814	Major facilitator Superfamily
AXW78_RS11300	COG0776	regulation of translation
AXW78_RS11310	COG2318	DinB family
AXW78_RS11320	COG1115	amino acid carrier protein
AXW78_RS11340	COG1187	pseudouridine synthase activity
AXW78_RS11345	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AXW78_RS11350	COG1136	(ABC) transporter
AXW78_RS11390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW78_RS11415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW78_RS11450	COG1247	-acetyltransferase
AXW78_RS11475	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AXW78_RS11485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW78_RS11515	COG0583	DNA-binding transcription factor activity
AXW78_RS11520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXW78_RS11540	COG0583	DNA-binding transcription factor activity
AXW78_RS11545	COG2258	MOSC domain
AXW78_RS11560	COG1132	(ABC) transporter
AXW78_RS11565	COG1132	(ABC) transporter
AXW78_RS11585	COG1396	sequence-specific DNA binding
AXW78_RS11625	COG1595	DNA-templated transcription, initiation
AXW78_RS11655	COG1649	PFAM Uncharacterised BCR, COG1649
AXW78_RS11680	COG2971	BadF BadG BcrA BcrD
AXW78_RS11690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AXW78_RS11700	COG1846	Transcriptional regulator
AXW78_RS11715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW78_RS11730	COG1309	transcriptional regulator
AXW78_RS11750	COG0500	methyltransferase
AXW78_RS11750	COG3615	Tellurite resistance protein tehB
AXW78_RS11760	COG2226	methyltransferase
AXW78_RS11800	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXW78_RS11825	COG2002	toxin-antitoxin pair type II binding
AXW78_RS11835	COG0730	response to heat
AXW78_RS11840	COG0110	maltose O-acetyltransferase activity
AXW78_RS11855	COG2814	Major facilitator Superfamily
AXW78_RS11890	COG1115	amino acid carrier protein
AXW78_RS11895	COG2066	Belongs to the glutaminase family
AXW78_RS11900	COG4191	Histidine kinase
AXW78_RS11905	COG0784	Response regulator, receiver
AXW78_RS11910	COG0697	spore germination
AXW78_RS11915	COG0531	amino acid
AXW78_RS11930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AXW78_RS11935	COG1114	Component of the transport system for branched-chain amino acids
AXW78_RS11940	COG0531	amino acid
AXW78_RS11945	COG0322	excinuclease ABC activity
AXW78_RS11955	COG2207	Transcriptional regulator
AXW78_RS11980	COG5002	protein histidine kinase activity
AXW78_RS12010	COG0741	lytic transglycosylase activity
AXW78_RS12015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW78_RS12045	COG1396	sequence-specific DNA binding
AXW78_RS12075	COG0768	penicillin binding
AXW78_RS12080	COG1595	DNA-templated transcription, initiation
AXW78_RS12090	COG0768	penicillin binding
AXW78_RS12095	COG0768	penicillin binding
AXW78_RS12105	COG1408	metallophosphoesterase
AXW78_RS12115	COG1131	(ABC) transporter
AXW78_RS12125	COG1309	transcriptional regulator
AXW78_RS12140	COG1960	acyl-CoA dehydrogenase activity
AXW78_RS12145	COG0439	Biotin carboxylase
AXW78_RS12150	COG0511	ligase activity, forming carbon-carbon bonds
AXW78_RS12155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXW78_RS12160	COG1024	Enoyl-CoA hydratase
AXW78_RS12165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXW78_RS12170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXW78_RS12195	COG1686	Belongs to the peptidase S11 family
AXW78_RS12220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXW78_RS12235	COG3227	Zinc metalloprotease (Elastase)
AXW78_RS12240	COG2207	Transcriptional regulator
AXW78_RS12280	COG1733	regulation of RNA biosynthetic process
AXW78_RS12285	COG2226	methyltransferase
AXW78_RS12300	COG1942	4-Oxalocrotonate Tautomerase
AXW78_RS12305	COG0583	DNA-binding transcription factor activity
AXW78_RS12330	COG0697	spore germination
AXW78_RS12335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW78_RS12360	COG2323	membrane
AXW78_RS12365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AXW78_RS12375	COG3386	PFAM SMP-30 Gluconolaconase
AXW78_RS12385	COG3773	Cell wall hydrolase
AXW78_RS12395	COG0745	RESPONSE REGULATOR receiver
AXW78_RS12400	COG2205	protein histidine kinase activity
AXW78_RS12405	COG0488	(ABC) transporter
AXW78_RS12415	COG1136	(ABC) transporter
AXW78_RS12420	COG0577	efflux transmembrane transporter activity
AXW78_RS12440	COG0460	homoserine dehydrogenase
AXW78_RS12445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW78_RS12455	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXW78_RS12475	COG0582	viral genome integration into host DNA
AXW78_RS12510	COG2002	toxin-antitoxin pair type II binding
AXW78_RS12575	COG0582	viral genome integration into host DNA
AXW78_RS12580	COG4980	gas vesicle protein
AXW78_RS12580	COG1674	ftsk spoiiie
AXW78_RS12630	COG0740	serine-type endopeptidase activity
AXW78_RS12750	COG2124	cytochrome p450
AXW78_RS12785	COG0561	phosphatase activity
AXW78_RS12790	COG5002	protein histidine kinase activity
AXW78_RS12795	COG0768	penicillin binding
AXW78_RS12800	COG1819	glycosyl
AXW78_RS12805	COG1794	racemase activity, acting on amino acids and derivatives
AXW78_RS12825	COG2205	protein histidine kinase activity
AXW78_RS12860	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AXW78_RS12865	COG0604	alcohol dehydrogenase
AXW78_RS12870	COG0671	phosphoesterase, PA-phosphatase related
AXW78_RS12875	COG0768	penicillin binding
AXW78_RS12885	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS12930	COG0584	glycerophosphoryl diester phosphodiesterase
AXW78_RS12950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW78_RS12955	COG0697	spore germination
AXW78_RS12990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXW78_RS13000	COG2223	nitrite transmembrane transporter activity
AXW78_RS13020	COG0592	DNA-directed DNA polymerase activity
AXW78_RS13040	COG3878	Protein conserved in bacteria
AXW78_RS13065	COG4667	esterase of the alpha-beta hydrolase superfamily
AXW78_RS13105	COG0322	excinuclease ABC activity
AXW78_RS13145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW78_RS13170	COG1011	Hydrolase
AXW78_RS13175	COG0745	RESPONSE REGULATOR receiver
AXW78_RS13180	COG5002	protein histidine kinase activity
AXW78_RS13195	COG1136	(ABC) transporter
AXW78_RS13200	COG0577	efflux transmembrane transporter activity
AXW78_RS13205	COG1073	alpha beta
AXW78_RS13210	COG0657	acetylesterase activity
AXW78_RS13215	COG0076	glutamate decarboxylase activity
AXW78_RS13230	COG1523	belongs to the glycosyl hydrolase 13 family
AXW78_RS13235	COG3227	Zinc metalloprotease (Elastase)
AXW78_RS13240	COG0737	Belongs to the 5'-nucleotidase family
AXW78_RS13255	COG0201	protein transport
AXW78_RS13260	COG0697	spore germination
AXW78_RS13265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW78_RS13300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW78_RS13315	COG2959	enzyme of heme biosynthesis
AXW78_RS13355	COG1309	transcriptional regulator
AXW78_RS13370	COG3284	Transcriptional regulator
AXW78_RS13385	COG1349	DNA-binding transcription factor activity
AXW78_RS13400	COG1959	2 iron, 2 sulfur cluster binding
AXW78_RS13415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXW78_RS13420	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXW78_RS13425	COG0022	dehydrogenase e1 component
AXW78_RS13430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXW78_RS13440	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS13470	COG4176	ABC-type proline glycine betaine transport system permease component
AXW78_RS13475	COG0517	IMP dehydrogenase activity
AXW78_RS13475	COG4175	Glycine betaine
AXW78_RS13505	COG2153	protein acetylation
AXW78_RS13510	COG3397	chitin binding
AXW78_RS13530	COG2205	protein histidine kinase activity
AXW78_RS13535	COG2226	methyltransferase
AXW78_RS13540	COG2315	Protein conserved in bacteria
AXW78_RS13590	COG0456	acetyltransferase
AXW78_RS13610	COG0514	ATP-dependent DNA helicase (RecQ)
AXW78_RS13640	COG4637	Psort location Cytoplasmic, score
AXW78_RS13655	COG3397	chitin binding
AXW78_RS13670	COG1162	GTPase activity
AXW78_RS13675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXW78_RS13680	COG1115	amino acid carrier protein
AXW78_RS13685	COG1012	belongs to the aldehyde dehydrogenase family
AXW78_RS13690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXW78_RS13700	COG3938	Belongs to the proline racemase family
AXW78_RS13705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXW78_RS13750	COG1078	dGTPase activity
AXW78_RS13755	COG0586	Pfam SNARE associated Golgi protein
AXW78_RS13765	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AXW78_RS13770	COG4166	transmembrane transport
AXW78_RS13780	COG4948	Mandelate Racemase Muconate Lactonizing
AXW78_RS13795	COG0667	Aldo Keto reductase
AXW78_RS13840	COG5002	protein histidine kinase activity
AXW78_RS13840	COG3850	Histidine kinase
AXW78_RS13845	COG0745	RESPONSE REGULATOR receiver
AXW78_RS13870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXW78_RS13880	COG1164	Oligoendopeptidase f
AXW78_RS13885	COG1307	EDD domain protein, DegV family
AXW78_RS13925	COG2814	Major facilitator Superfamily
AXW78_RS13935	COG1664	Polymer-forming cytoskeletal
AXW78_RS13940	COG0789	Transcriptional regulator
AXW78_RS13945	COG4533	DNA binding
AXW78_RS13950	COG0477	Major facilitator Superfamily
AXW78_RS13950	COG2814	Major facilitator Superfamily
AXW78_RS13970	COG2261	transglycosylase associated protein
AXW78_RS13985	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXW78_RS14010	COG0436	Aminotransferase
AXW78_RS14015	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AXW78_RS14065	COG0628	permease
AXW78_RS14080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW78_RS14085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW78_RS14115	COG2746	aminoglycoside 3-N-acetyltransferase activity
AXW78_RS14135	COG0697	spore germination
AXW78_RS14155	COG4912	Dna alkylation repair
AXW78_RS14160	COG0346	lactoylglutathione lyase activity
AXW78_RS14175	COG0861	Integral membrane protein TerC family
AXW78_RS14180	COG1368	sulfuric ester hydrolase activity
AXW78_RS14185	COG0488	(ABC) transporter
AXW78_RS14190	COG1033	growth of symbiont in host cell
AXW78_RS14190	COG2409	Drug exporters of the RND superfamily
AXW78_RS14195	COG1309	transcriptional regulator
AXW78_RS14210	COG0287	Prephenate dehydrogenase
AXW78_RS14225	COG1605	Chorismate mutase
AXW78_RS14225	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AXW78_RS14270	COG0346	lactoylglutathione lyase activity
AXW78_RS14285	COG1595	DNA-templated transcription, initiation
AXW78_RS14320	COG1172	Belongs to the binding-protein-dependent transport system permease family
AXW78_RS14330	COG2390	Transcriptional regulator
AXW78_RS14335	COG1070	Carbohydrate kinase
AXW78_RS14355	COG2329	Antibiotic biosynthesis monooxygenase
AXW78_RS14375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXW78_RS14390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AXW78_RS14395	COG4187	Peptidase family M20/M25/M40
AXW78_RS14400	COG1414	Transcriptional regulator
AXW78_RS14405	COG0833	amino acid
AXW78_RS14415	COG3239	Fatty acid desaturase
AXW78_RS14425	COG2720	vancomycin resistance protein
AXW78_RS14430	COG1785	Belongs to the alkaline phosphatase family
AXW78_RS14440	COG3655	Transcriptional regulator
AXW78_RS14470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW78_RS14475	COG0346	lactoylglutathione lyase activity
AXW78_RS14495	COG0714	Associated with various cellular activities
AXW78_RS14520	COG0463	Glycosyl transferase, family 2
AXW78_RS14545	COG0463	Glycosyl transferase, family 2
AXW78_RS14555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXW78_RS14560	COG0753	catalase activity
AXW78_RS14595	COG0714	Associated with various cellular activities
AXW78_RS14665	COG0778	Nitroreductase
AXW78_RS14670	COG1846	Transcriptional regulator
AXW78_RS14690	COG4884	unkown
AXW78_RS14690	COG3831	ATPase activity
AXW78_RS14715	COG0456	acetyltransferase
AXW78_RS14730	COG0697	spore germination
AXW78_RS14735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW78_RS14775	COG0730	response to heat
AXW78_RS14785	COG0833	amino acid
AXW78_RS14795	COG4335	DNA alkylation repair
AXW78_RS14805	COG5002	protein histidine kinase activity
AXW78_RS14810	COG0745	RESPONSE REGULATOR receiver
AXW78_RS14820	COG1136	(ABC) transporter
AXW78_RS14820	COG0577	efflux transmembrane transporter activity
AXW78_RS14855	COG0768	penicillin binding
AXW78_RS14890	COG1984	allophanate hydrolase subunit 2
AXW78_RS14895	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AXW78_RS14900	COG1414	Transcriptional regulator
AXW78_RS14915	COG0640	Transcriptional regulator
AXW78_RS14925	COG1960	acyl-CoA dehydrogenase activity
AXW78_RS14940	COG3314	Sporulation integral membrane protein YlbJ
AXW78_RS14970	COG0574	Belongs to the PEP-utilizing enzyme family
AXW78_RS14970	COG3848	Pyruvate phosphate dikinase
AXW78_RS14980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW78_RS14995	COG5577	PFAM Coat F domain
AXW78_RS15000	COG3403	YqcI/YcgG family
AXW78_RS15005	COG1280	lysine exporter protein (LysE YggA)
AXW78_RS15010	COG1113	amino acid transport
AXW78_RS15035	COG1063	alcohol dehydrogenase
AXW78_RS15045	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AXW78_RS15055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXW78_RS15070	COG0737	Belongs to the 5'-nucleotidase family
AXW78_RS15075	COG2267	carboxylic ester hydrolase activity
AXW78_RS15080	COG1335	isochorismatase
AXW78_RS15090	COG0583	DNA-binding transcription factor activity
AXW78_RS15095	COG0598	Magnesium transport protein CorA
AXW78_RS15115	COG1073	alpha beta
AXW78_RS15135	COG0415	Belongs to the DNA photolyase family
AXW78_RS15160	COG0288	reversible hydration of carbon dioxide
AXW78_RS15170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AXW78_RS15175	COG5609	conserved protein (DUF2294)
AXW78_RS15190	COG0697	spore germination
AXW78_RS15200	COG0456	acetyltransferase
AXW78_RS15205	COG1575	Belongs to the MenA family. Type 1 subfamily
AXW78_RS15210	COG0803	Belongs to the bacterial solute-binding protein 9 family
AXW78_RS15215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AXW78_RS15220	COG1121	(ABC) transporter
AXW78_RS15245	COG0798	PFAM Bile acid sodium symporter
AXW78_RS15250	COG0346	lactoylglutathione lyase activity
AXW78_RS15255	COG0640	Transcriptional regulator
AXW78_RS15275	COG0346	lactoylglutathione lyase activity
AXW78_RS15300	COG0745	RESPONSE REGULATOR receiver
AXW78_RS15305	COG5002	protein histidine kinase activity
AXW78_RS15305	COG3850	Histidine kinase
AXW78_RS15335	COG2197	response regulator
AXW78_RS15360	COG2814	Major facilitator Superfamily
AXW78_RS15375	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AXW78_RS15385	COG1690	Belongs to the RtcB family
AXW78_RS15395	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AXW78_RS15410	COG1136	(ABC) transporter
AXW78_RS15415	COG0577	efflux transmembrane transporter activity
AXW78_RS15420	COG5002	protein histidine kinase activity
AXW78_RS15420	COG3850	Histidine kinase
AXW78_RS15430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXW78_RS15455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXW78_RS15475	COG0662	Cupin 2, conserved barrel domain protein
AXW78_RS15480	COG2207	Transcriptional regulator
AXW78_RS15480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXW78_RS15500	COG3409	Peptidoglycan-binding domain 1 protein
AXW78_RS15500	COG5632	N-Acetylmuramoyl-L-alanine amidase
AXW78_RS15575	COG1876	peptidase activity
AXW78_RS15580	COG2843	Capsule synthesis protein
AXW78_RS15590	COG0477	Major facilitator Superfamily
AXW78_RS15605	COG1846	Transcriptional regulator
AXW78_RS15610	COG2814	Major facilitator Superfamily
AXW78_RS15620	COG2031	fatty acid transporter
AXW78_RS15630	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXW78_RS15685	COG1288	antiporter activity
AXW78_RS15690	COG2356	endonuclease I
AXW78_RS15695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AXW78_RS15715	COG1733	regulation of RNA biosynthetic process
AXW78_RS15720	COG0778	Nitroreductase
AXW78_RS15750	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS15760	COG1131	(ABC) transporter
AXW78_RS15785	COG1011	Hydrolase
AXW78_RS15790	COG2365	Tyrosine phosphatase family
AXW78_RS15825	COG0628	permease
AXW78_RS15885	COG1253	flavin adenine dinucleotide binding
AXW78_RS15890	COG0789	Transcriptional regulator
AXW78_RS15900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AXW78_RS15925	COG0697	spore germination
AXW78_RS15935	COG1357	PFAM Pentapeptide repeats (8 copies)
AXW78_RS15940	COG3813	Protein conserved in bacteria
AXW78_RS15945	COG2706	6-phosphogluconolactonase activity
AXW78_RS15950	COG1070	Carbohydrate kinase
AXW78_RS15960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AXW78_RS15965	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AXW78_RS15975	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AXW78_RS15980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AXW78_RS16000	COG0840	transmembrane signaling receptor activity
AXW78_RS16010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXW78_RS16010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXW78_RS16015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AXW78_RS16015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AXW78_RS16020	COG1733	regulation of RNA biosynthetic process
AXW78_RS16040	COG0814	amino acid
AXW78_RS16065	COG2188	Transcriptional regulator
AXW78_RS16070	COG0673	inositol 2-dehydrogenase activity
AXW78_RS16090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW78_RS16110	COG0384	phenazine biosynthesis protein PhzF
AXW78_RS16130	COG0318	PFAM AMP-dependent synthetase and ligase
AXW78_RS16135	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXW78_RS16140	COG1733	regulation of RNA biosynthetic process
AXW78_RS16145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXW78_RS16175	COG1191	sigma factor activity
AXW78_RS16225	COG1151	hydroxylamine reductase activity
AXW78_RS16255	COG2072	flavoprotein involved in K transport
AXW78_RS16290	COG0604	alcohol dehydrogenase
AXW78_RS16295	COG1113	amino acid transport
AXW78_RS16300	COG2814	Major facilitator Superfamily
AXW78_RS16330	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AXW78_RS16335	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AXW78_RS16350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXW78_RS16355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW78_RS16360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW78_RS16365	COG3739	integral membrane protein
AXW78_RS16395	COG0583	DNA-binding transcription factor activity
AXW78_RS16420	COG1193	negative regulation of DNA recombination
AXW78_RS16435	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AXW78_RS16440	COG1164	Oligoendopeptidase f
AXW78_RS16445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXW78_RS16470	COG0584	glycerophosphoryl diester phosphodiesterase
AXW78_RS16480	COG0640	Transcriptional regulator
AXW78_RS16485	COG0604	alcohol dehydrogenase
AXW78_RS16495	COG0457	Tetratricopeptide repeat
AXW78_RS16505	COG2808	Putative FMN-binding domain
AXW78_RS16510	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AXW78_RS16520	COG0385	Bile acid
AXW78_RS16525	COG0277	FAD linked oxidase domain protein
AXW78_RS16550	COG0457	Tetratricopeptide repeat
AXW78_RS16580	COG2205	protein histidine kinase activity
AXW78_RS16585	COG0745	RESPONSE REGULATOR receiver
AXW78_RS16605	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AXW78_RS16615	COG2814	Major facilitator Superfamily
AXW78_RS16660	COG0488	(ABC) transporter
AXW78_RS16690	COG3852	Histidine kinase
AXW78_RS16700	COG1285	pathogenesis
AXW78_RS16710	COG2514	catechol 2,3-dioxygenase activity
AXW78_RS16715	COG2720	vancomycin resistance protein
AXW78_RS16750	COG0716	FMN binding
AXW78_RS16760	COG1051	belongs to the nudix hydrolase family
AXW78_RS16780	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS16790	COG0165	Argininosuccinate lyase
AXW78_RS16805	COG4145	pantothenate transmembrane transporter activity
AXW78_RS16815	COG1012	belongs to the aldehyde dehydrogenase family
AXW78_RS16820	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS16830	COG1657	PFAM Prenyltransferase squalene oxidase
AXW78_RS16835	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AXW78_RS16840	COG2962	Rard protein
AXW78_RS16845	COG3326	Membrane
AXW78_RS16860	COG0489	protein tyrosine kinase activity
AXW78_RS16870	COG0314	molybdopterin synthase activity
AXW78_RS16875	COG0303	'Molybdopterin
AXW78_RS16880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXW78_RS16885	COG2116	formate transmembrane transporter activity
AXW78_RS16895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AXW78_RS16900	COG5609	conserved protein (DUF2294)
AXW78_RS16905	COG2427	Protein of unknown function (DUF1641)
AXW78_RS16910	COG3383	formate dehydrogenase (NAD+) activity
AXW78_RS16915	COG0697	spore germination
AXW78_RS16960	COG2226	methyltransferase
AXW78_RS16965	COG4166	transmembrane transport
AXW78_RS16975	COG4166	transmembrane transport
AXW78_RS16980	COG1301	dicarboxylic acid transport
AXW78_RS16985	COG1316	TRANSCRIPTIONal
AXW78_RS16995	COG1595	DNA-templated transcription, initiation
AXW78_RS17005	COG1131	(ABC) transporter
AXW78_RS17015	COG0673	inositol 2-dehydrogenase activity
AXW78_RS17020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXW78_RS17025	COG0187	DNA topoisomerase II activity
AXW78_RS17030	COG1832	CoA-binding protein
AXW78_RS17035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXW78_RS17040	COG0745	RESPONSE REGULATOR receiver
AXW78_RS17050	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AXW78_RS17050	COG1328	CTP reductase activity
AXW78_RS17060	COG4841	protein insertion into membrane
AXW78_RS17065	COG0824	Thioesterase
AXW78_RS17095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXW78_RS17110	COG1132	(ABC) transporter
AXW78_RS17115	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AXW78_RS17145	COG2211	Major facilitator Superfamily
AXW78_RS17155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AXW78_RS17170	COG0183	Belongs to the thiolase family
AXW78_RS17175	COG0318	PFAM AMP-dependent synthetase and ligase
AXW78_RS17180	COG1268	BioY protein
AXW78_RS17185	COG0318	PFAM AMP-dependent synthetase and ligase
AXW78_RS17200	COG1396	sequence-specific DNA binding
AXW78_RS17245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXW78_RS17255	COG5002	protein histidine kinase activity
AXW78_RS17260	COG0400	carboxylic ester hydrolase activity
AXW78_RS17265	COG0346	lactoylglutathione lyase activity
AXW78_RS17270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXW78_RS17280	COG0069	glutamate synthase activity
AXW78_RS17285	COG1902	pentaerythritol trinitrate reductase activity
AXW78_RS17290	COG1329	Transcriptional regulator
AXW78_RS17295	COG0010	Belongs to the arginase family
AXW78_RS17320	COG2226	methyltransferase
AXW78_RS17345	COG4846	Membrane protein involved in cytochrome C biogenesis
AXW78_RS17350	COG0785	Cytochrome C biogenesis protein
AXW78_RS17360	COG1473	amidohydrolase
AXW78_RS17370	COG1131	(ABC) transporter
AXW78_RS17385	COG0583	DNA-binding transcription factor activity
AXW78_RS17395	COG1346	cytolysis
AXW78_RS17410	COG0730	response to heat
AXW78_RS17435	COG1132	(ABC) transporter
AXW78_RS17440	COG1132	(ABC) transporter
AXW78_RS17465	COG3639	organic phosphonate transmembrane transporter activity
AXW78_RS17475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW78_RS17480	COG0737	Belongs to the 5'-nucleotidase family
AXW78_RS17510	COG1695	Transcriptional regulator
AXW78_RS17525	COG4974	Belongs to the 'phage' integrase family
AXW78_RS17530	COG0174	glutamine synthetase
AXW78_RS17535	COG0789	Transcriptional regulator
AXW78_RS17540	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AXW78_RS17545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXW78_RS17550	COG2860	membrane
AXW78_RS17560	COG0464	growth
AXW78_RS17590	COG3584	3D domain protein
AXW78_RS17590	COG1388	LysM domain
AXW78_RS17595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXW78_RS17595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXW78_RS17595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXW78_RS17600	COG1105	Belongs to the carbohydrate kinase PfkB family
AXW78_RS17605	COG1349	DNA-binding transcription factor activity
AXW78_RS17610	COG1979	alcohol dehydrogenase
AXW78_RS17615	COG2322	membrane
AXW78_RS17630	COG1113	amino acid transport
AXW78_RS17640	COG1473	amidohydrolase
AXW78_RS17645	COG1408	metallophosphoesterase
AXW78_RS17650	COG2116	formate transmembrane transporter activity
AXW78_RS17665	COG2217	Heavy metal translocating P-type atpase
AXW78_RS17670	COG2608	mercury ion transmembrane transporter activity
AXW78_RS17675	COG1937	Protein conserved in bacteria
AXW78_RS17685	COG2819	hydrolase of the alpha beta superfamily
AXW78_RS17690	COG1120	ATPase activity
AXW78_RS17695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW78_RS17700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW78_RS17705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXW78_RS17710	COG0708	Exodeoxyribonuclease III
AXW78_RS17715	COG2169	Transcriptional regulator
AXW78_RS17720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXW78_RS17725	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AXW78_RS17735	COG2364	Membrane
AXW78_RS17750	COG2267	carboxylic ester hydrolase activity
AXW78_RS17755	COG3300	MHYT domain
AXW78_RS17755	COG5001	Diguanylate cyclase
AXW78_RS17775	COG1086	Polysaccharide biosynthesis protein
AXW78_RS17790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXW78_RS17805	COG0840	transmembrane signaling receptor activity
AXW78_RS17815	COG1404	Belongs to the peptidase S8 family
AXW78_RS17820	COG3773	Cell wall hydrolase
AXW78_RS17830	COG1368	sulfuric ester hydrolase activity
AXW78_RS17835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AXW78_RS17860	COG4550	Control of competence regulator ComK, YlbF/YmcA
AXW78_RS17870	COG1013	pyruvate-flavodoxin oxidoreductase activity
AXW78_RS17875	COG0674	pyruvate-flavodoxin oxidoreductase activity
AXW78_RS17875	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AXW78_RS17885	COG2359	stage V sporulation protein S
AXW78_RS17890	COG1692	metallophosphoesterase
AXW78_RS17910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXW78_RS17930	COG0300	oxidoreductase activity
AXW78_RS17935	COG0612	Peptidase, M16
AXW78_RS17940	COG0612	Peptidase, M16
AXW78_RS17945	COG1079	Belongs to the binding-protein-dependent transport system permease family
AXW78_RS17950	COG4603	Belongs to the binding-protein-dependent transport system permease family
AXW78_RS17955	COG3845	ABC transporter
AXW78_RS17960	COG1744	ABC transporter substrate-binding protein PnrA-like
AXW78_RS17965	COG2188	Transcriptional regulator
AXW78_RS17980	COG0740	serine-type endopeptidase activity
AXW78_RS17985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AXW78_RS17995	COG0527	aspartate kinase activity
AXW78_RS18000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXW78_RS18005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXW78_RS18010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXW78_RS18015	COG1873	PFAM PRC-barrel domain
AXW78_RS18020	COG0612	Peptidase, M16
AXW78_RS18025	COG0726	polysaccharide deacetylase
AXW78_RS18040	COG0196	riboflavin kinase activity
AXW78_RS18050	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AXW78_RS18055	COG1550	Protein conserved in bacteria
AXW78_RS18065	COG1358	cellular component organization or biogenesis
AXW78_RS18070	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AXW78_RS18075	COG0195	Participates in both transcription termination and antitermination
AXW78_RS18095	COG0750	zinc metalloprotease
AXW78_RS18105	COG4589	Belongs to the CDS family
AXW78_RS18150	COG4974	Belongs to the 'phage' integrase family
AXW78_RS18160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXW78_RS18165	COG0758	DNA mediated transformation
AXW78_RS18170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AXW78_RS18210	COG1837	Belongs to the UPF0109 family
AXW78_RS18220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AXW78_RS18230	COG0552	protein localization to endoplasmic reticulum
AXW78_RS18235	COG1196	nuclear chromosome segregation
AXW78_RS18245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXW78_RS18250	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS18255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AXW78_RS18270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AXW78_RS18275	COG1461	Dihydroxyacetone kinase
AXW78_RS18280	COG1302	Protein conserved in bacteria
AXW78_RS18295	COG1564	THIamine pyrophosphokinase
AXW78_RS18300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AXW78_RS18310	COG2815	serine threonine protein kinase
AXW78_RS18310	COG0515	serine threonine protein kinase
AXW78_RS18315	COG0631	protein serine/threonine phosphatase activity
AXW78_RS18325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AXW78_RS18325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AXW78_RS18340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AXW78_RS18345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXW78_RS18365	COG1561	YicC-like family, N-terminal region
AXW78_RS18370	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AXW78_RS18385	COG0006	proline dipeptidase activity
AXW78_RS18400	COG3069	C4-dicarboxylate transmembrane transporter activity
AXW78_RS18460	COG0564	pseudouridine synthase activity
AXW78_RS18480	COG3599	regulation of cell shape
AXW78_RS18485	COG2302	S4 RNA-binding domain
AXW78_RS18490	COG0762	integral membrane protein
AXW78_RS18500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AXW78_RS18510	COG1873	PFAM PRC-barrel domain
AXW78_RS18515	COG1191	sigma factor activity
AXW78_RS18520	COG1191	sigma factor activity
AXW78_RS18530	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AXW78_RS18535	COG0849	cell division
AXW78_RS18555	COG0772	Belongs to the SEDS family
AXW78_RS18575	COG0768	penicillin binding
AXW78_RS18580	COG0768	penicillin binding
AXW78_RS18600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AXW78_RS18615	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AXW78_RS18620	COG1399	metal-binding, possibly nucleic acid-binding protein
AXW78_RS18630	COG3480	Lon protease (S16) C-terminal proteolytic domain
AXW78_RS18635	COG1752	Esterase of the alpha-beta hydrolase superfamily
AXW78_RS18640	COG3314	Sporulation integral membrane protein YlbJ
AXW78_RS18650	COG0742	ribosomal rna small subunit methyltransferase
AXW78_RS18665	COG3679	Belongs to the UPF0342 family
AXW78_RS18670	COG0406	alpha-ribazole phosphatase activity
AXW78_RS18685	COG2340	Cysteine-rich secretory protein family
AXW78_RS18700	COG3336	cytochrome c oxidase
AXW78_RS18735	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AXW78_RS18740	COG0772	Belongs to the SEDS family
AXW78_RS18750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AXW78_RS18755	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AXW78_RS18765	COG4896	Protein conserved in bacteria
AXW78_RS18780	COG1217	gtp-binding protein TYPA
AXW78_RS18790	COG0483	inositol monophosphate 1-phosphatase activity
AXW78_RS18810	COG1982	Orn Lys Arg decarboxylase major
AXW78_RS18860	COG0022	dehydrogenase e1 component
AXW78_RS18865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXW78_RS18880	COG0561	phosphatase activity
AXW78_RS18890	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AXW78_RS18895	COG0569	domain protein
AXW78_RS18915	COG0583	DNA-binding transcription factor activity
AXW78_RS18920	COG0517	IMP dehydrogenase activity
AXW78_RS18930	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AXW78_RS18940	COG4703	Protein of unknown function (DUF1797)
AXW78_RS18955	COG2200	EAL domain
AXW78_RS18960	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS18965	COG1408	metallophosphoesterase
AXW78_RS19010	COG2814	Major facilitator Superfamily
AXW78_RS19030	COG3209	COG3209 Rhs family protein
AXW78_RS19040	COG2205	protein histidine kinase activity
AXW78_RS19050	COG0436	Aminotransferase
AXW78_RS19055	COG1609	Transcriptional regulator
AXW78_RS19060	COG3833	ABC-type maltose transport systems, permease component
AXW78_RS19065	COG1175	transmembrane transport
AXW78_RS19070	COG2182	Extracellular solute-binding protein
AXW78_RS19080	COG0366	Alpha amylase catalytic
AXW78_RS19085	COG3842	ATPase activity
AXW78_RS19125	COG0183	Belongs to the thiolase family
AXW78_RS19155	COG1695	Transcriptional regulator
AXW78_RS19160	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS19180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXW78_RS19185	COG0436	Aminotransferase
AXW78_RS19220	COG2084	Dehydrogenase
AXW78_RS19230	COG2199	diguanylate cyclase activity
AXW78_RS19235	COG0778	Nitroreductase
AXW78_RS19260	COG2190	(PTS) system
AXW78_RS19260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXW78_RS19260	COG1263	PTS System
AXW78_RS19265	COG3711	transcriptional antiterminator
AXW78_RS19275	COG2188	Transcriptional regulator
AXW78_RS19285	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AXW78_RS19310	COG1547	Domain of unknown function (DUF309)
AXW78_RS19320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AXW78_RS19325	COG4086	secreted protein
AXW78_RS19330	COG0561	phosphatase activity
AXW78_RS19335	COG0697	spore germination
AXW78_RS19350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AXW78_RS19375	COG0733	neurotransmitter:sodium symporter activity
AXW78_RS19395	COG1686	Belongs to the peptidase S11 family
AXW78_RS19400	COG1725	Transcriptional regulator
AXW78_RS19405	COG1131	(ABC) transporter
AXW78_RS19425	COG1846	Transcriptional regulator
AXW78_RS19440	COG0598	Magnesium transport protein CorA
AXW78_RS19465	COG4974	Belongs to the 'phage' integrase family
AXW78_RS19475	COG0735	belongs to the Fur family
AXW78_RS19480	COG1300	Membrane
AXW78_RS19500	COG0667	Aldo Keto reductase
AXW78_RS19505	COG0656	L-ascorbic acid biosynthetic process
AXW78_RS19510	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AXW78_RS19510	COG0456	acetyltransferase
AXW78_RS19520	COG1525	nuclease
AXW78_RS19520	COG4085	toxin activity
AXW78_RS19520	COG0737	Belongs to the 5'-nucleotidase family
AXW78_RS19530	COG0596	Alpha beta hydrolase
AXW78_RS19535	COG2056	Na+-H+ antiporter family
AXW78_RS19540	COG1609	Transcriptional regulator
AXW78_RS19545	COG0456	acetyltransferase
AXW78_RS19550	COG1073	alpha beta
AXW78_RS19565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXW78_RS19565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXW78_RS19570	COG0307	riboflavin synthase, alpha
AXW78_RS19600	COG2226	methyltransferase
AXW78_RS19600	COG1073	alpha beta
AXW78_RS19615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AXW78_RS19625	COG1757	Na H antiporter
AXW78_RS19630	COG0737	Belongs to the 5'-nucleotidase family
AXW78_RS19640	COG1522	sequence-specific DNA binding
AXW78_RS19685	COG0300	oxidoreductase activity
AXW78_RS19690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW78_RS19695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AXW78_RS19700	COG1760	l-serine dehydratase
AXW78_RS19705	COG1760	l-serine dehydratase
AXW78_RS19740	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXW78_RS19745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW78_RS19755	COG1376	ErfK ybiS ycfS ynhG family protein
AXW78_RS19760	COG4129	membrane
AXW78_RS19765	COG1126	abc transporter atp-binding protein
AXW78_RS19770	COG0765	amino acid transport
AXW78_RS19775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW78_RS19795	COG2323	membrane
AXW78_RS19800	COG0772	Belongs to the SEDS family
AXW78_RS19810	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXW78_RS19815	COG0022	dehydrogenase e1 component
AXW78_RS19820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXW78_RS19825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXW78_RS19840	COG0280	phosphate acetyltransferase
AXW78_RS19850	COG3290	protein histidine kinase activity
AXW78_RS19850	COG3829	transcription factor binding
AXW78_RS19860	COG0584	glycerophosphoryl diester phosphodiesterase
AXW78_RS19865	COG3093	addiction module antidote protein HigA
AXW78_RS19880	COG0750	zinc metalloprotease
AXW78_RS19885	COG0497	DNA recombination
AXW78_RS19895	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AXW78_RS19905	COG0142	geranyltranstransferase activity
AXW78_RS19930	COG1302	Protein conserved in bacteria
AXW78_RS19935	COG0439	Biotin carboxylase
AXW78_RS19940	COG0511	ligase activity, forming carbon-carbon bonds
AXW78_RS19985	COG3854	ATPases associated with a variety of cellular activities
AXW78_RS20010	COG0006	proline dipeptidase activity
AXW78_RS20025	COG3872	metal-dependent enzyme
AXW78_RS20035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXW78_RS20050	COG1695	Transcriptional regulator
AXW78_RS20070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXW78_RS20075	COG1609	Transcriptional regulator
AXW78_RS20085	COG2076	Multidrug Resistance protein
AXW78_RS20090	COG2076	Multidrug Resistance protein
AXW78_RS20125	COG1725	Transcriptional regulator
AXW78_RS20155	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AXW78_RS20220	COG1459	type II secretion system
AXW78_RS20225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AXW78_RS20280	COG0646	methionine synthase
AXW78_RS20280	COG1410	methionine synthase
AXW78_RS20285	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AXW78_RS20285	COG0646	methionine synthase
AXW78_RS20290	COG0626	cystathionine gamma-synthase activity
AXW78_RS20295	COG0626	cystathionine gamma-synthase activity
AXW78_RS20315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW78_RS20320	COG1940	carbohydrate kinase activity
AXW78_RS20325	COG4483	Protein conserved in bacteria
AXW78_RS20330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AXW78_RS20335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AXW78_RS20340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AXW78_RS20345	COG0704	Plays a role in the regulation of phosphate uptake
AXW78_RS20355	COG0573	inorganic phosphate transmembrane transporter activity
AXW78_RS20360	COG0573	inorganic phosphate transmembrane transporter activity
AXW78_RS20365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXW78_RS20370	COG0768	penicillin binding
AXW78_RS20375	COG0477	Major facilitator Superfamily
AXW78_RS20380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXW78_RS20390	COG5521	maltodextrose utilization protein MalA
AXW78_RS20405	COG0735	belongs to the Fur family
AXW78_RS20410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AXW78_RS20415	COG1121	(ABC) transporter
AXW78_RS20420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXW78_RS20450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AXW78_RS20455	COG2384	SAM-dependent methyltransferase
AXW78_RS20465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXW78_RS20470	COG0358	DNA primase activity
AXW78_RS20480	COG0517	IMP dehydrogenase activity
AXW78_RS20495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AXW78_RS20500	COG0295	cytidine deaminase activity
AXW78_RS20505	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AXW78_RS20520	COG1702	phosphate starvation-inducible protein PhoH
AXW78_RS20540	COG1610	YqeY-like protein
AXW78_RS20545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AXW78_RS20550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AXW78_RS20555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AXW78_RS20585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXW78_RS20590	COG1733	regulation of RNA biosynthetic process
AXW78_RS20615	COG1466	dna polymerase III delta subunit
AXW78_RS20625	COG0658	competence protein
AXW78_RS20625	COG2333	competence protein COMEC
AXW78_RS20630	COG2131	deaminase
AXW78_RS20635	COG1555	photosystem II stabilization
AXW78_RS20635	COG1596	polysaccharide export
AXW78_RS20640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AXW78_RS20645	COG2226	methyltransferase
AXW78_RS20650	COG0799	negative regulation of ribosome biogenesis
AXW78_RS20655	COG1713	HD superfamily hydrolase involved in NAD metabolism
AXW78_RS20665	COG1534	Rna-binding protein
AXW78_RS20675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AXW78_RS20680	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AXW78_RS20705	COG1595	DNA-templated transcription, initiation
AXW78_RS20715	COG0778	Nitroreductase
AXW78_RS20720	COG2357	RelA SpoT domain protein
AXW78_RS20730	COG1785	Belongs to the alkaline phosphatase family
AXW78_RS20740	COG2267	carboxylic ester hydrolase activity
AXW78_RS20775	COG1404	Belongs to the peptidase S8 family
AXW78_RS20780	COG3186	Phenylalanine-4-hydroxylase
AXW78_RS20790	COG2514	catechol 2,3-dioxygenase activity
AXW78_RS20795	COG2259	Doxx family
AXW78_RS20835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXW78_RS20845	COG1012	belongs to the aldehyde dehydrogenase family
AXW78_RS20845	COG1454	alcohol dehydrogenase
AXW78_RS20850	COG0626	cystathionine gamma-synthase activity
AXW78_RS20855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AXW78_RS20880	COG0768	penicillin binding
AXW78_RS20900	COG0826	peptidase U32
AXW78_RS20905	COG0826	peptidase U32
AXW78_RS20910	COG4122	O-methyltransferase activity
AXW78_RS20915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AXW78_RS20945	COG0628	permease
AXW78_RS20965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXW78_RS20980	COG1104	cysteine desulfurase activity
AXW78_RS20985	COG1959	2 iron, 2 sulfur cluster binding
AXW78_RS20990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AXW78_RS21000	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AXW78_RS21030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXW78_RS21040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AXW78_RS21040	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AXW78_RS21045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AXW78_RS21050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXW78_RS21050	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXW78_RS21060	COG2244	polysaccharide biosynthetic process
AXW78_RS21065	COG2323	membrane
AXW78_RS21075	COG1862	Preprotein translocase
AXW78_RS21105	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AXW78_RS21135	COG0157	Belongs to the NadC ModD family
AXW78_RS21140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AXW78_RS21145	COG1104	cysteine desulfurase activity
AXW78_RS21150	COG1827	regulation of RNA biosynthetic process
AXW78_RS21155	COG2258	MOSC domain
AXW78_RS21165	COG0077	Prephenate dehydratase
AXW78_RS21170	COG0577	efflux transmembrane transporter activity
AXW78_RS21175	COG0577	efflux transmembrane transporter activity
AXW78_RS21180	COG1136	(ABC) transporter
AXW78_RS21185	COG5002	protein histidine kinase activity
AXW78_RS21190	COG0745	RESPONSE REGULATOR receiver
AXW78_RS21200	COG3290	protein histidine kinase activity
AXW78_RS21210	COG2868	ribosomal protein
AXW78_RS21220	COG1530	ribonuclease E activity
AXW78_RS21225	COG1994	Peptidase M50
AXW78_RS21230	COG0739	heme binding
AXW78_RS21235	COG2894	cell division
AXW78_RS21255	COG1077	Cell shape determining protein MreB Mrl
AXW78_RS21290	COG5632	N-Acetylmuramoyl-L-alanine amidase
AXW78_RS21500	COG0285	dihydrofolate synthase activity
AXW78_RS21515	COG1388	LysM domain
AXW78_RS21525	COG0113	porphobilinogen synthase activity
AXW78_RS21530	COG1587	Uroporphyrinogen-III synthase
AXW78_RS21540	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AXW78_RS21550	COG1846	Transcriptional regulator
AXW78_RS21555	COG1764	response to oxidative stress
AXW78_RS21570	COG0470	DNA polymerase III
AXW78_RS21570	COG1067	ATP-dependent peptidase activity
AXW78_RS21615	COG0622	Phosphoesterase
AXW78_RS21630	COG5401	PFAM Sporulation and spore germination
AXW78_RS21650	COG1309	transcriptional regulator
AXW78_RS21665	COG2197	response regulator
AXW78_RS21670	COG2233	PERMEase
AXW78_RS21675	COG0402	S-adenosylhomocysteine deaminase activity
AXW78_RS21680	COG1983	PspC domain protein
AXW78_RS21685	COG1396	sequence-specific DNA binding
AXW78_RS21690	COG0697	spore germination
AXW78_RS21700	COG1959	2 iron, 2 sulfur cluster binding
AXW78_RS21705	COG1668	transmembrane transport
AXW78_RS21710	COG4152	abc transporter atp-binding protein
AXW78_RS21715	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AXW78_RS21720	COG1360	Flagellar Motor Protein
AXW78_RS21725	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AXW78_RS21730	COG1876	peptidase activity
AXW78_RS21735	COG0824	Thioesterase
AXW78_RS21740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AXW78_RS21745	COG1053	succinate dehydrogenase
AXW78_RS21750	COG2009	succinate dehydrogenase
AXW78_RS21755	COG1719	4-vinyl reductase, 4VR
AXW78_RS21765	COG3118	belongs to the thioredoxin family
AXW78_RS21770	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AXW78_RS21775	COG2086	electron transfer activity
AXW78_RS21780	COG1024	Enoyl-CoA hydratase
AXW78_RS21785	COG1309	transcriptional regulator
AXW78_RS21790	COG0318	PFAM AMP-dependent synthetase and ligase
AXW78_RS21810	COG2318	DinB family
AXW78_RS21835	COG1131	(ABC) transporter
AXW78_RS21840	COG2205	protein histidine kinase activity
AXW78_RS21845	COG0745	RESPONSE REGULATOR receiver
AXW78_RS21855	COG4895	conserved protein (DUF2196)
AXW78_RS21860	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AXW78_RS21875	COG4509	Sortase family
AXW78_RS21880	COG1120	ATPase activity
AXW78_RS21895	COG5386	Cell surface protein
AXW78_RS21905	COG5386	Cell surface protein
AXW78_RS21910	COG1114	Component of the transport system for branched-chain amino acids
AXW78_RS21915	COG1187	pseudouridine synthase activity
AXW78_RS21925	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AXW78_RS21925	COG1796	DNA polymerase
AXW78_RS21930	COG1286	toxin biosynthetic process
AXW78_RS21970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXW78_RS21980	COG1418	mRNA catabolic process
AXW78_RS21995	COG2814	Major facilitator Superfamily
AXW78_RS22000	COG1566	PFAM secretion protein HlyD family protein
AXW78_RS22005	COG1309	transcriptional regulator
AXW78_RS22010	COG1363	Peptidase, m42
AXW78_RS22035	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AXW78_RS22045	COG1484	DNA-dependent DNA replication
AXW78_RS22050	COG3611	Membrane attachment protein
AXW78_RS22060	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AXW78_RS22065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AXW78_RS22075	COG1971	Probably functions as a manganese efflux pump
AXW78_RS22085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXW78_RS22085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXW78_RS22090	COG5002	protein histidine kinase activity
AXW78_RS22095	COG0745	RESPONSE REGULATOR receiver
AXW78_RS22115	COG0538	isocitrate dehydrogenase activity
AXW78_RS22120	COG0372	Belongs to the citrate synthase family
AXW78_RS22130	COG0628	permease
AXW78_RS22135	COG3030	protein affecting phage T7 exclusion by the F plasmid
AXW78_RS22160	COG1725	Transcriptional regulator
AXW78_RS22165	COG0281	malic enzyme
AXW78_RS22170	COG0587	DNA-directed DNA polymerase activity
AXW78_RS22185	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AXW78_RS22200	COG4109	DRTGG domain
AXW78_RS22215	COG0006	proline dipeptidase activity
AXW78_RS22255	COG0662	Cupin 2, conserved barrel domain protein
AXW78_RS22270	COG1028	Short-chain dehydrogenase reductase Sdr
AXW78_RS22275	COG0589	response to stress
AXW78_RS22310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXW78_RS22335	COG0827	DNA restriction-modification system
AXW78_RS22340	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AXW78_RS22345	COG3874	Sporulation protein YtfJ
AXW78_RS22360	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AXW78_RS22370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXW78_RS22385	COG1104	cysteine desulfurase activity
AXW78_RS22395	COG0583	DNA-binding transcription factor activity
AXW78_RS22400	COG0697	spore germination
AXW78_RS22405	COG1309	transcriptional regulator
AXW78_RS22410	COG1956	GAF domain-containing protein
AXW78_RS22470	COG1595	DNA-templated transcription, initiation
AXW78_RS22480	COG0110	maltose O-acetyltransferase activity
AXW78_RS22485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXW78_RS22490	COG0454	-acetyltransferase
AXW78_RS22495	COG0517	IMP dehydrogenase activity
AXW78_RS22500	COG0123	including yeast histone deacetylase and acetoin utilization protein
AXW78_RS22505	COG2267	carboxylic ester hydrolase activity
AXW78_RS22515	COG0745	RESPONSE REGULATOR receiver
AXW78_RS22525	COG0666	response to abiotic stimulus
AXW78_RS22535	COG1970	mechanosensitive ion channel activity
AXW78_RS22560	COG1609	Transcriptional regulator
AXW78_RS22565	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AXW78_RS22565	COG1605	Chorismate mutase
AXW78_RS22570	COG4851	CamS sex pheromone cAM373 precursor
AXW78_RS22575	COG3118	belongs to the thioredoxin family
AXW78_RS22585	COG2309	aminopeptidase activity
AXW78_RS22600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW78_RS22615	COG1674	ftsk spoiiie
AXW78_RS22620	COG1388	LysM domain
AXW78_RS22620	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXW78_RS22630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXW78_RS22640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXW78_RS22645	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AXW78_RS22650	COG1363	Peptidase, m42
AXW78_RS22660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW78_RS22675	COG0510	thiamine kinase activity
AXW78_RS22680	COG1523	belongs to the glycosyl hydrolase 13 family
AXW78_RS22690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXW78_RS22695	COG1349	DNA-binding transcription factor activity
AXW78_RS22700	COG1187	pseudouridine synthase activity
AXW78_RS22705	COG2244	polysaccharide biosynthetic process
AXW78_RS22710	COG2081	HI0933 family
AXW78_RS22715	COG2814	Major facilitator Superfamily
AXW78_RS22725	COG3832	glyoxalase III activity
AXW78_RS22745	COG1329	Transcriptional regulator
AXW78_RS22770	COG0314	molybdopterin synthase activity
AXW78_RS22775	COG1763	Mo-molybdopterin cofactor biosynthetic process
AXW78_RS22780	COG0303	'Molybdopterin
AXW78_RS22790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AXW78_RS22795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AXW78_RS22820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXW78_RS22830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXW78_RS22875	COG2814	Major facilitator Superfamily
AXW78_RS22880	COG0475	glutathione-regulated potassium exporter activity
AXW78_RS22885	COG0490	domain, Protein
AXW78_RS22890	COG0582	viral genome integration into host DNA
AXW78_RS22905	COG1136	(ABC) transporter
AXW78_RS22925	COG1242	4 iron, 4 sulfur cluster binding
AXW78_RS22930	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AXW78_RS22935	COG1794	racemase activity, acting on amino acids and derivatives
AXW78_RS22955	COG2267	carboxylic ester hydrolase activity
AXW78_RS22960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AXW78_RS22965	COG0671	phosphoesterase, PA-phosphatase related
AXW78_RS22970	COG0438	transferase activity, transferring glycosyl groups
AXW78_RS22990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW78_RS23035	COG5002	protein histidine kinase activity
AXW78_RS23040	COG3852	Histidine kinase
AXW78_RS23045	COG2267	carboxylic ester hydrolase activity
AXW78_RS23050	COG1368	sulfuric ester hydrolase activity
AXW78_RS23060	COG4895	conserved protein (DUF2196)
AXW78_RS23075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXW78_RS23080	COG1116	anion transmembrane transporter activity
AXW78_RS23085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXW78_RS23110	COG0494	nUDIX hydrolase
AXW78_RS23140	COG2076	Multidrug Resistance protein
AXW78_RS23145	COG2076	Multidrug Resistance protein
AXW78_RS23155	COG1854	S-ribosylhomocysteine lyase activity
AXW78_RS23165	COG0288	reversible hydration of carbon dioxide
AXW78_RS23175	COG1271	oxidase subunit
AXW78_RS23180	COG1294	oxidase, subunit
AXW78_RS23195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXW78_RS23215	COG1842	Phage shock protein A
AXW78_RS23245	COG5002	protein histidine kinase activity
AXW78_RS23250	COG0745	RESPONSE REGULATOR receiver
AXW78_RS23275	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AXW78_RS23280	COG1597	lipid kinase activity
AXW78_RS23295	COG0586	Pfam SNARE associated Golgi protein
AXW78_RS23305	COG0577	efflux transmembrane transporter activity
AXW78_RS23310	COG1136	(ABC) transporter
AXW78_RS23315	COG2207	Transcriptional regulator
AXW78_RS23315	COG3708	Transcriptional regulator
AXW78_RS23325	COG1131	(ABC) transporter
AXW78_RS23330	COG5658	integral membrane protein
AXW78_RS23335	COG0640	Transcriptional regulator
AXW78_RS23345	COG0745	RESPONSE REGULATOR receiver
AXW78_RS23350	COG2205	protein histidine kinase activity
AXW78_RS23355	COG0577	efflux transmembrane transporter activity
AXW78_RS23360	COG0577	efflux transmembrane transporter activity
AXW78_RS23365	COG1136	(ABC) transporter
AXW78_RS23370	COG0577	efflux transmembrane transporter activity
AXW78_RS23385	COG2188	Transcriptional regulator
AXW78_RS23405	COG3964	amidohydrolase
AXW78_RS23425	COG4948	Mandelate Racemase Muconate Lactonizing
AXW78_RS23435	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AXW78_RS23440	COG0596	Alpha beta hydrolase
AXW78_RS23450	COG1169	isochorismate synthase
AXW78_RS23455	COG1575	Belongs to the MenA family. Type 1 subfamily
AXW78_RS23460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AXW78_RS23485	COG0058	SHG alpha-glucan phosphorylase activity
AXW78_RS23495	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AXW78_RS23610	COG0544	peptidyl-prolyl cis-trans isomerase activity
AXW78_RS23645	COG1285	pathogenesis
AXW78_RS23650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXW78_RS23665	COG2155	Conserved Protein
AXW78_RS23670	COG1098	S1 RNA binding domain
AXW78_RS23675	COG0436	Aminotransferase
AXW78_RS23680	COG1522	sequence-specific DNA binding
AXW78_RS23685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AXW78_RS23690	COG2267	carboxylic ester hydrolase activity
AXW78_RS23700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AXW78_RS23720	COG5018	Exonuclease
AXW78_RS23725	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AXW78_RS23745	COG2050	protein possibly involved in aromatic compounds catabolism
AXW78_RS23755	COG1268	BioY protein
AXW78_RS23760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AXW78_RS23765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXW78_RS23780	COG3584	3D domain protein
AXW78_RS23795	COG1252	NADH dehydrogenase
AXW78_RS23810	COG3708	Transcriptional regulator
AXW78_RS23825	COG1683	Conserved Protein
AXW78_RS23840	COG0316	Belongs to the HesB IscA family
AXW78_RS23855	COG1252	NADH dehydrogenase
AXW78_RS23865	COG2274	protein secretion by the type I secretion system
AXW78_RS23870	COG0390	transport system, permease component
AXW78_RS23875	COG2824	Alkylphosphonate utilization operon protein PhnA
AXW78_RS23900	COG4837	Protein of unknown function (DUF1462)
AXW78_RS23905	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AXW78_RS23915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AXW78_RS23920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AXW78_RS23930	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXW78_RS23935	COG0647	UMP catabolic process
AXW78_RS23945	COG2445	Protein of unknown function DUF86
AXW78_RS23950	COG1494	fructose-1,6-bisphosphatase
AXW78_RS23965	COG4470	Protein conserved in bacteria
AXW78_RS23975	COG0789	Transcriptional regulator
AXW78_RS23980	COG4377	Putative membrane peptidase family (DUF2324)
AXW78_RS24005	COG0739	heme binding
AXW78_RS24015	COG3377	Domain of unknown function (DUF1805)
AXW78_RS24020	COG0737	Belongs to the 5'-nucleotidase family
AXW78_RS24030	COG0719	Fe-S assembly protein
AXW78_RS24035	COG0822	iron-sulfur transferase activity
AXW78_RS24040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AXW78_RS24045	COG0719	Fe-S assembly protein
AXW78_RS24050	COG0396	ATPase activity
AXW78_RS24055	COG1464	Belongs to the NlpA lipoprotein family
AXW78_RS24060	COG1464	Belongs to the NlpA lipoprotein family
AXW78_RS24065	COG2011	ABC-type metal ion transport system permease component
AXW78_RS24080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXW78_RS24085	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AXW78_RS24095	COG1393	Belongs to the ArsC family
AXW78_RS24115	COG0039	L-malate dehydrogenase activity
AXW78_RS24130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXW78_RS24135	COG1960	acyl-CoA dehydrogenase activity
AXW78_RS24140	COG0183	Belongs to the thiolase family
AXW78_RS24145	COG1024	Enoyl-CoA hydratase
AXW78_RS24145	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXW78_RS24155	COG1686	Belongs to the peptidase S11 family
AXW78_RS24170	COG0011	TIGRFAM Protein of
AXW78_RS24175	COG0840	transmembrane signaling receptor activity
AXW78_RS24190	COG2814	Major facilitator Superfamily
AXW78_RS24195	COG0531	amino acid
AXW78_RS24220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXW78_RS24255	COG0586	Pfam SNARE associated Golgi protein
AXW78_RS24265	COG1376	ErfK ybiS ycfS ynhG family protein
AXW78_RS24270	COG0745	RESPONSE REGULATOR receiver
AXW78_RS24275	COG5002	protein histidine kinase activity
AXW78_RS24305	COG0840	transmembrane signaling receptor activity
AXW78_RS24310	COG2151	metal-sulfur cluster biosynthetic enzyme
AXW78_RS24315	COG3227	Zinc metalloprotease (Elastase)
AXW78_RS24335	COG0475	glutathione-regulated potassium exporter activity
AXW78_RS24340	COG0490	domain, Protein
AXW78_RS24345	COG1115	amino acid carrier protein
AXW78_RS24350	COG0783	Belongs to the Dps family
AXW78_RS24365	COG1611	Belongs to the LOG family
AXW78_RS24375	COG1528	Iron-storage protein
AXW78_RS24380	COG2311	Membrane
AXW78_RS24385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXW78_RS24390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXW78_RS24395	COG1115	amino acid carrier protein
AXW78_RS24400	COG1115	amino acid carrier protein
AXW78_RS24405	COG2910	NAD(P)H-binding
AXW78_RS24420	COG0656	L-ascorbic acid biosynthetic process
AXW78_RS24425	COG2814	Major facilitator Superfamily
AXW78_RS24430	COG1733	regulation of RNA biosynthetic process
AXW78_RS24440	COG1252	NADH dehydrogenase
AXW78_RS24495	COG0488	(ABC) transporter
AXW78_RS24500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXW78_RS24520	COG1335	isochorismatase
AXW78_RS24525	COG1522	sequence-specific DNA binding
AXW78_RS24580	COG0557	exoribonuclease II activity
AXW78_RS24585	COG1647	Serine aminopeptidase, S33
AXW78_RS24590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AXW78_RS24595	COG1346	cytolysis
AXW78_RS24630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AXW78_RS24645	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AXW78_RS24670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AXW78_RS24685	COG2323	membrane
AXW78_RS24695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXW78_RS24705	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AXW78_RS24715	COG1051	belongs to the nudix hydrolase family
AXW78_RS24725	COG0492	ferredoxin-NADP+ reductase activity
AXW78_RS24730	COG0457	Tetratricopeptide repeat
AXW78_RS24735	COG0110	maltose O-acetyltransferase activity
AXW78_RS24755	COG1950	PFAM Membrane protein of
AXW78_RS24765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AXW78_RS24785	COG0789	Transcriptional regulator
AXW78_RS24805	COG0583	DNA-binding transcription factor activity
AXW78_RS24815	COG0655	NAD(P)H dehydrogenase (quinone) activity
AXW78_RS24820	COG0488	(ABC) transporter
AXW78_RS24830	COG1132	(ABC) transporter
AXW78_RS24835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXW78_RS24840	COG3409	Peptidoglycan-binding domain 1 protein
AXW78_RS24840	COG0793	Belongs to the peptidase S41A family
AXW78_RS24845	COG2177	Part of the ABC transporter FtsEX involved in
AXW78_RS24850	COG2884	Cell division ATP-binding protein ftsE
AXW78_RS24860	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AXW78_RS24870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AXW78_RS24875	COG1278	Cold shock
AXW78_RS24880	COG1040	competence protein
AXW78_RS24885	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AXW78_RS24890	COG0791	NLP P60 protein
AXW78_RS24890	COG1388	LysM domain
AXW78_RS24895	COG1733	regulation of RNA biosynthetic process
AXW78_RS24900	COG1307	EDD domain protein, DegV family
AXW78_RS24905	COG1739	Uncharacterized protein family UPF0029
AXW78_RS24910	COG1316	TRANSCRIPTIONal
AXW78_RS24915	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AXW78_RS24920	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AXW78_RS24925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AXW78_RS24935	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AXW78_RS24935	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AXW78_RS24955	COG1486	melibiose metabolic process
AXW78_RS24960	COG1447	Phosphotransferase system cellobiose-specific component IIA
AXW78_RS24965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXW78_RS24975	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AXW78_RS24985	COG1447	Phosphotransferase system cellobiose-specific component IIA
AXW78_RS24995	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AXW78_RS25000	COG1301	dicarboxylic acid transport
AXW78_RS25010	COG0346	lactoylglutathione lyase activity
AXW78_RS25015	COG1511	domain protein
AXW78_RS25020	COG0583	DNA-binding transcription factor activity
AXW78_RS25025	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AXW78_RS25035	COG1271	oxidase subunit
AXW78_RS25040	COG1294	oxidase, subunit
AXW78_RS25045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AXW78_RS25065	COG1620	l-lactate permease
AXW78_RS25075	COG2389	metal-binding protein
AXW78_RS25085	COG1368	sulfuric ester hydrolase activity
AXW78_RS25095	COG0791	NLP P60 protein
AXW78_RS25095	COG1388	LysM domain
AXW78_RS25100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXW78_RS25110	COG1215	transferase activity, transferring glycosyl groups
AXW78_RS25120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXW78_RS25125	COG1388	LysM domain
AXW78_RS25125	COG3584	3D domain protein
AXW78_RS25150	COG4715	Zinc finger, swim domain protein
AXW78_RS25155	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AXW78_RS25195	COG0577	efflux transmembrane transporter activity
AXW78_RS25200	COG1136	(ABC) transporter
AXW78_RS25230	COG0745	RESPONSE REGULATOR receiver
AXW78_RS25235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXW78_RS25255	COG1216	Glycosyl transferase, family 2
AXW78_RS25270	COG0438	transferase activity, transferring glycosyl groups
AXW78_RS25275	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AXW78_RS25285	COG1181	Belongs to the D-alanine--D-alanine ligase family
AXW78_RS25290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AXW78_RS25295	COG1086	Polysaccharide biosynthesis protein
AXW78_RS25300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AXW78_RS25305	COG4464	protein tyrosine phosphatase activity
AXW78_RS25310	COG0489	protein tyrosine kinase activity
AXW78_RS25315	COG3944	biosynthesis protein
AXW78_RS25320	COG0489	protein tyrosine kinase activity
AXW78_RS25335	COG1609	Transcriptional regulator
AXW78_RS25345	COG0739	heme binding
AXW78_RS25360	COG3279	Response regulator of the LytR AlgR family
AXW78_RS25365	COG2385	sporulation resulting in formation of a cellular spore
AXW78_RS25380	COG4836	Membrane
AXW78_RS25385	COG1007	ATP synthesis coupled electron transport
AXW78_RS25390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXW78_RS25395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AXW78_RS25405	COG0839	Belongs to the complex I subunit 6 family
AXW78_RS25425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXW78_RS25445	COG5001	Diguanylate cyclase
AXW78_RS25445	COG3300	MHYT domain
AXW78_RS25495	COG0356	it plays a direct role in the translocation of protons across the membrane
AXW78_RS25530	COG0698	ribose 5-phosphate isomerase
AXW78_RS25545	COG2259	Doxx family
AXW78_RS25550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXW78_RS25570	COG0009	L-threonylcarbamoyladenylate synthase
AXW78_RS25605	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AXW78_RS25610	COG1494	fructose-1,6-bisphosphatase
AXW78_RS25630	COG4821	SIS domain
AXW78_RS25640	COG3343	RNA polymerase activity
AXW78_RS25650	COG1960	acyl-CoA dehydrogenase activity
AXW78_RS25655	COG1960	acyl-CoA dehydrogenase activity
AXW78_RS25660	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXW78_RS25665	COG0183	Belongs to the thiolase family
AXW78_RS25670	COG2181	nitrate reductase activity
AXW78_RS25670	COG0247	lactate metabolic process
AXW78_RS25675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXW78_RS25685	COG3300	MHYT domain
AXW78_RS25685	COG5001	Diguanylate cyclase
AXW78_RS25700	COG3227	Zinc metalloprotease (Elastase)
AXW78_RS25705	COG2197	response regulator
AXW78_RS25710	COG4585	Histidine kinase
AXW78_RS25715	COG0842	Transport permease protein
AXW78_RS25720	COG1131	(ABC) transporter
AXW78_RS25725	COG0024	Methionine aminopeptidase
AXW78_RS25735	COG2234	aminopeptidase activity
AXW78_RS25755	COG1595	DNA-templated transcription, initiation
AXW78_RS25765	COG4506	Protein conserved in bacteria
AXW78_RS25770	COG1619	proteins homologs of microcin C7 resistance protein MccF
AXW78_RS25785	COG0010	Belongs to the arginase family
AXW78_RS25795	COG2814	Major facilitator Superfamily
AXW78_RS25800	COG0789	Transcriptional regulator
AXW78_RS25805	COG0584	glycerophosphoryl diester phosphodiesterase
AXW78_RS25810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXW78_RS25820	COG1994	Peptidase M50
AXW78_RS25830	COG1078	dGTPase activity
AXW78_RS25835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AXW78_RS25840	COG1120	ATPase activity
AXW78_RS25845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW78_RS25850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXW78_RS25870	COG0280	phosphate acetyltransferase
AXW78_RS25885	COG3773	Cell wall hydrolase
AXW78_RS25895	COG2363	Small membrane protein
AXW78_RS25905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXW78_RS25910	COG2233	PERMEase
AXW78_RS25915	COG0561	phosphatase activity
AXW78_RS25920	COG2814	Major facilitator Superfamily
AXW78_RS25930	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AXW78_RS25935	COG1131	(ABC) transporter
AXW78_RS25940	COG2755	lipolytic protein G-D-S-L family
AXW78_RS25945	COG1609	Transcriptional regulator
AXW78_RS25955	COG0460	homoserine dehydrogenase
AXW78_RS25965	COG2873	o-acetylhomoserine
AXW78_RS25970	COG1011	Hydrolase
AXW78_RS25975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXW78_RS25985	COG2197	response regulator
AXW78_RS25990	COG4585	Histidine kinase
AXW78_RS25990	COG2203	Gaf domain
AXW78_RS25995	COG0351	phosphomethylpyrimidine kinase
AXW78_RS26000	COG3706	GGDEF domain
AXW78_RS26005	COG2879	small protein
AXW78_RS26010	COG1966	Carbon starvation protein
AXW78_RS26015	COG3279	Response regulator of the LytR AlgR family
AXW78_RS26020	COG0477	Major facilitator Superfamily
AXW78_RS26030	COG0438	transferase activity, transferring glycosyl groups
AXW78_RS26045	COG0840	transmembrane signaling receptor activity
AXW78_RS26055	COG1607	acyl-coa hydrolase
AXW78_RS26060	COG1216	Glycosyl transferase, family 2
AXW78_RS26075	COG1216	Glycosyl transferase, family 2
AXW78_RS26085	COG4485	Bacterial membrane protein, YfhO
AXW78_RS26090	COG0463	Glycosyl transferase, family 2
AXW78_RS26095	COG0488	(ABC) transporter
AXW78_RS26100	COG1309	transcriptional regulator
AXW78_RS26105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXW78_RS26110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW78_RS26110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXW78_RS26115	COG0628	permease
AXW78_RS26135	COG3275	phosphorelay sensor kinase activity
AXW78_RS26140	COG2814	Major facilitator Superfamily
AXW78_RS26145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXW78_RS26150	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AXW78_RS26170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXW78_RS26175	COG1272	protein, Hemolysin III
AXW78_RS26225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXW78_RS26230	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AXW78_RS26235	COG4853	Protein conserved in bacteria
AXW78_RS26245	COG5002	protein histidine kinase activity
AXW78_RS26250	COG0745	RESPONSE REGULATOR receiver
AXW78_RS26280	COG0305	Participates in initiation and elongation during chromosome replication
AXW78_RS26290	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AXW78_RS26295	COG4241	membrane
AXW78_RS26315	COG0012	GTP binding
AXW78_RS26320	COG4481	Protein conserved in bacteria
AXW78_RS26325	COG0668	transmembrane transport
AXW78_RS26335	COG1475	DNA binding
AXW78_RS26340	COG1192	Involved in chromosome partitioning
AXW78_RS26365	COG1847	R3H domain protein
AXW78_RS26380	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AXW78_RS26955	COG4166	transmembrane transport
AXW78_RS27300	COG0488	(ABC) transporter
AXW78_RS27410	COG1215	transferase activity, transferring glycosyl groups
AXW78_RS27615	COG1012	belongs to the aldehyde dehydrogenase family
AXW78_RS27640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AXW78_RS27710	COG1473	amidohydrolase
AXW78_RS27845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXW78_RS27905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXW78_RS27905	COG2190	(PTS) system
AXW78_RS27905	COG1263	PTS System
AXW78_RS28065	COG2310	stress, protein
AXW78_RS28100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AXW78_RS28315	COG1194	a g-specific adenine glycosylase
AXW78_RS28345	COG1132	(ABC) transporter
AXW78_RS28535	COG3290	protein histidine kinase activity
AXW78_RS28610	COG0840	transmembrane signaling receptor activity
AXW78_RS29755	COG0488	(ABC) transporter
AXW78_RS29835	COG0531	amino acid
AXW78_RS29860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AXW78_RS30025	COG0488	(ABC) transporter
AXW78_RS30055	COG2252	PERMEase
AXW78_RS30225	COG0187	DNA topoisomerase II activity
AXW78_RS30240	COG0187	DNA topoisomerase II activity
AXW78_RS30255	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXW78_RS30485	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AXW78_RS30520	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AXW78_RS30585	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXW78_RS30710	COG1428	Deoxynucleoside kinase
AXW78_RS30975	COG0187	DNA topoisomerase II activity
AXW78_RS31070	COG1686	Belongs to the peptidase S11 family
AXW78_RS31095	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AXW78_RS31350	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AXW78_RS31385	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner