locus-tag	class	description
BTB_RS00010	COG0592	DNA-directed DNA polymerase activity
BTB_RS00015	COG2501	S4 domain
BTB_RS00025	COG0187	DNA topoisomerase II activity
BTB_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTB_RS00065	COG0517	IMP dehydrogenase activity
BTB_RS00065	COG0516	GMP reductase activity
BTB_RS00070	COG1686	Belongs to the peptidase S11 family
BTB_RS00100	COG1428	Deoxynucleoside kinase
BTB_RS00105	COG1428	Deoxynucleoside kinase
BTB_RS00110	COG1335	isochorismatase
BTB_RS00115	COG0590	tRNA wobble adenosine to inosine editing
BTB_RS00120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTB_RS00175	COG1982	Orn Lys Arg decarboxylase major
BTB_RS00185	COG0470	DNA polymerase III
BTB_RS00190	COG1774	PSP1 C-terminal conserved region
BTB_RS00200	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BTB_RS00210	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BTB_RS00215	COG2002	toxin-antitoxin pair type II binding
BTB_RS00225	COG0084	hydrolase, TatD family'
BTB_RS00245	COG4466	Protein conserved in bacteria
BTB_RS00260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BTB_RS00265	COG0251	oxidation-reduction process
BTB_RS00295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTB_RS00300	COG2002	toxin-antitoxin pair type II binding
BTB_RS00305	COG2244	polysaccharide biosynthetic process
BTB_RS00310	COG3956	TIGRFAM MazG family protein
BTB_RS00315	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BTB_RS00335	COG1098	S1 RNA binding domain
BTB_RS00350	COG2208	phosphoserine phosphatase activity
BTB_RS00360	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTB_RS00365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTB_RS00380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTB_RS00385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BTB_RS00390	COG0512	Glutamine amidotransferase of anthranilate synthase
BTB_RS00395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTB_RS00400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BTB_RS00405	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BTB_RS00410	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BTB_RS00415	COG1396	sequence-specific DNA binding
BTB_RS00420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTB_RS00510	COG3880	PFAM UvrB UvrC protein
BTB_RS00520	COG0542	response to heat
BTB_RS00525	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BTB_RS00535	COG4956	integral membrane protein (PIN domain superfamily)
BTB_RS00555	COG1045	serine acetyltransferase
BTB_RS00570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTB_RS00575	COG3688	RNA-binding protein containing a PIN domain
BTB_RS00585	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTB_RS00590	COG0250	Participates in transcription elongation, termination and antitermination
BTB_RS00595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BTB_RS00610	COG0222	ribosome binding
BTB_RS00615	COG2813	Specifically methylates the guanine in position
BTB_RS00625	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BTB_RS00630	COG1358	cellular component organization or biogenesis
BTB_RS00635	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BTB_RS00655	COG0051	transcription antitermination factor activity, RNA binding
BTB_RS00660	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BTB_RS00700	COG0255	Belongs to the universal ribosomal protein uL29 family
BTB_RS00760	COG0201	protein transport
BTB_RS00770	COG0024	Methionine aminopeptidase
BTB_RS00780	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BTB_RS00815	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BTB_RS00840	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTB_RS00845	COG0489	protein tyrosine kinase activity
BTB_RS00855	COG2194	sulfuric ester hydrolase activity
BTB_RS00860	COG0726	polysaccharide deacetylase
BTB_RS00940	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BTB_RS00945	COG4856	YbbR-like protein
BTB_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS00995	COG2011	ABC-type metal ion transport system permease component
BTB_RS01000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BTB_RS01005	COG1464	Belongs to the NlpA lipoprotein family
BTB_RS01010	COG0604	alcohol dehydrogenase
BTB_RS01020	COG0277	FAD linked oxidase domain protein
BTB_RS01025	COG2271	Major facilitator Superfamily
BTB_RS01035	COG2814	Major facilitator Superfamily
BTB_RS01055	COG0601	transmembrane transport
BTB_RS01060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTB_RS01065	COG0444	Belongs to the ABC transporter superfamily
BTB_RS01070	COG4608	Belongs to the ABC transporter superfamily
BTB_RS01075	COG4166	transmembrane transport
BTB_RS01090	COG4166	transmembrane transport
BTB_RS01095	COG4166	transmembrane transport
BTB_RS01100	COG0656	L-ascorbic acid biosynthetic process
BTB_RS01120	COG4149	molybdate abc transporter
BTB_RS01125	COG0725	ABC transporter, periplasmic molybdate-binding protein
BTB_RS01130	COG1910	domain protein
BTB_RS01140	COG0697	spore germination
BTB_RS01150	COG0204	Acyl-transferase
BTB_RS01155	COG1609	Transcriptional regulator
BTB_RS01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTB_RS01185	COG5298	Protein conserved in bacteria
BTB_RS01205	COG0488	(ABC) transporter
BTB_RS01215	COG0747	negative chemotaxis
BTB_RS01220	COG0601	transmembrane transport
BTB_RS01225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTB_RS01230	COG0444	Belongs to the ABC transporter superfamily
BTB_RS01235	COG4608	Belongs to the ABC transporter superfamily
BTB_RS01240	COG0561	phosphatase activity
BTB_RS01260	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BTB_RS01265	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTB_RS01275	COG0531	amino acid
BTB_RS01285	COG2814	Major facilitator Superfamily
BTB_RS01295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BTB_RS01305	COG4294	response to UV
BTB_RS01310	COG0705	Rhomboid family
BTB_RS01320	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BTB_RS01325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTB_RS01330	COG0864	Transcriptional regulator
BTB_RS01335	COG2337	Toxic component of a toxin-antitoxin (TA) module
BTB_RS01340	COG2183	response to ionizing radiation
BTB_RS01435	COG0802	atpase or kinase
BTB_RS01440	COG1214	PFAM Peptidase M22, glycoprotease
BTB_RS01445	COG0456	acetyltransferase
BTB_RS01455	COG0488	(ABC) transporter
BTB_RS01470	COG1266	CAAX protease self-immunity
BTB_RS01490	COG5444	nuclease activity
BTB_RS01505	COG2252	PERMEase
BTB_RS01515	COG5002	protein histidine kinase activity
BTB_RS01540	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BTB_RS01560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTB_RS01565	COG0506	proline dehydrogenase activity
BTB_RS01620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTB_RS01630	COG1215	transferase activity, transferring glycosyl groups
BTB_RS01650	COG0697	spore germination
BTB_RS01675	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTB_RS01680	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BTB_RS01685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTB_RS01695	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTB_RS01710	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BTB_RS01720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BTB_RS01730	COG0151	Belongs to the GarS family
BTB_RS01740	COG0583	DNA-binding transcription factor activity
BTB_RS01765	COG0210	DNA helicase
BTB_RS01775	COG4851	CamS sex pheromone cAM373 precursor
BTB_RS01790	COG1335	isochorismatase
BTB_RS01805	COG2011	ABC-type metal ion transport system permease component
BTB_RS01810	COG1464	Belongs to the NlpA lipoprotein family
BTB_RS01820	COG0003	Pfam Anion-transporting ATPase
BTB_RS01825	COG1846	Transcriptional regulator
BTB_RS01830	COG4682	membrane
BTB_RS01850	COG1597	lipid kinase activity
BTB_RS01855	COG0546	phosphoglycolate phosphatase activity
BTB_RS01860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTB_RS01870	COG1012	belongs to the aldehyde dehydrogenase family
BTB_RS01875	COG2076	Multidrug Resistance protein
BTB_RS01885	COG2309	aminopeptidase activity
BTB_RS01900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTB_RS01910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTB_RS01915	COG4807	Protein conserved in bacteria
BTB_RS01940	COG1757	Na H antiporter
BTB_RS01945	COG1473	amidohydrolase
BTB_RS01965	COG0450	alkyl hydroperoxide reductase
BTB_RS01985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTB_RS01990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTB_RS01995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTB_RS02000	COG0492	ferredoxin-NADP+ reductase activity
BTB_RS02010	COG0166	Belongs to the GPI family
BTB_RS02035	COG5002	protein histidine kinase activity
BTB_RS02055	COG3541	Predicted nucleotidyltransferase
BTB_RS02060	COG2814	Major facilitator Superfamily
BTB_RS02065	COG0723	plastoquinol--plastocyanin reductase activity
BTB_RS02065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTB_RS02075	COG0765	amino acid transport
BTB_RS02080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTB_RS02090	COG0840	transmembrane signaling receptor activity
BTB_RS02115	COG0549	Belongs to the carbamate kinase family
BTB_RS02120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTB_RS02130	COG0277	FAD linked oxidase domain protein
BTB_RS02135	COG0366	Alpha amylase catalytic
BTB_RS02140	COG1263	PTS System
BTB_RS02140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTB_RS02140	COG2190	(PTS) system
BTB_RS02170	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BTB_RS02190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTB_RS02195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTB_RS02200	COG1116	anion transmembrane transporter activity
BTB_RS02205	COG0488	(ABC) transporter
BTB_RS02250	COG2270	Major facilitator Superfamily
BTB_RS02280	COG2310	stress, protein
BTB_RS02285	COG2310	stress, protein
BTB_RS02290	COG2310	stress, protein
BTB_RS02295	COG0861	Integral membrane protein TerC family
BTB_RS02305	COG3853	Toxic anion resistance protein (TelA)
BTB_RS02320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BTB_RS02330	COG1295	ribonuclease BN
BTB_RS02335	COG2217	Heavy metal translocating P-type atpase
BTB_RS02340	COG0697	spore germination
BTB_RS02360	COG0586	Pfam SNARE associated Golgi protein
BTB_RS02375	COG3871	stress protein (general stress protein 26)
BTB_RS02380	COG0387	Pfam Sodium calcium exchanger
BTB_RS02390	COG0535	radical SAM domain protein
BTB_RS02410	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BTB_RS02415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BTB_RS02430	COG3829	transcription factor binding
BTB_RS02440	COG0833	amino acid
BTB_RS02445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTB_RS02470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTB_RS02470	COG1263	PTS System
BTB_RS02475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTB_RS02490	COG1216	Glycosyl transferase, family 2
BTB_RS02500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTB_RS02500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTB_RS02505	COG0463	Glycosyl transferase, family 2
BTB_RS02515	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BTB_RS02535	COG1228	amidohydrolase
BTB_RS02540	COG1090	epimerase
BTB_RS02570	COG1988	membrane-bound metal-dependent
BTB_RS02575	COG1194	a g-specific adenine glycosylase
BTB_RS02595	COG3557	Belongs to the UPF0374 family
BTB_RS02600	COG1132	(ABC) transporter
BTB_RS02605	COG4129	membrane
BTB_RS02610	COG0070	glutamate synthase
BTB_RS02610	COG0067	glutamate synthase
BTB_RS02610	COG0069	glutamate synthase activity
BTB_RS02620	COG4555	ABC transporter
BTB_RS02640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTB_RS02645	COG0735	belongs to the Fur family
BTB_RS02765	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BTB_RS02790	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BTB_RS02800	COG2766	serine protein kinase
BTB_RS02820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTB_RS02830	COG1585	Membrane protein implicated in regulation of membrane protease activity
BTB_RS02835	COG2268	Band 7 protein
BTB_RS02845	COG3290	protein histidine kinase activity
BTB_RS02850	COG4565	transcriptional regulatory protein
BTB_RS02855	COG2851	Citrate transporter
BTB_RS02880	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BTB_RS02885	COG3842	ATPase activity
BTB_RS02890	COG1175	transmembrane transport
BTB_RS02895	COG0395	ABC-type sugar transport system, permease component
BTB_RS02905	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BTB_RS02910	COG0745	RESPONSE REGULATOR receiver
BTB_RS02915	COG5002	protein histidine kinase activity
BTB_RS02925	COG4990	cell redox homeostasis
BTB_RS02935	COG3290	protein histidine kinase activity
BTB_RS02940	COG4565	transcriptional regulatory protein
BTB_RS02945	COG3493	citrate carrier protein
BTB_RS02950	COG0281	malic enzyme
BTB_RS02960	COG0697	spore germination
BTB_RS02965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTB_RS02975	COG5002	protein histidine kinase activity
BTB_RS02980	COG0745	RESPONSE REGULATOR receiver
BTB_RS02990	COG0456	acetyltransferase
BTB_RS02990	COG0454	-acetyltransferase
BTB_RS02995	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTB_RS03000	COG3383	formate dehydrogenase (NAD+) activity
BTB_RS03005	COG2427	Protein of unknown function (DUF1641)
BTB_RS03020	COG0531	amino acid
BTB_RS03025	COG0640	Transcriptional regulator
BTB_RS03030	COG2217	Heavy metal translocating P-type atpase
BTB_RS03035	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BTB_RS03045	COG3227	Zinc metalloprotease (Elastase)
BTB_RS03065	COG2720	vancomycin resistance protein
BTB_RS03070	COG1316	TRANSCRIPTIONal
BTB_RS03075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTB_RS03080	COG0346	lactoylglutathione lyase activity
BTB_RS03085	COG1253	flavin adenine dinucleotide binding
BTB_RS03090	COG1027	Aspartate ammonia-lyase
BTB_RS03095	COG1620	l-lactate permease
BTB_RS03110	COG3104	oligopeptide transport
BTB_RS03115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTB_RS03120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTB_RS03125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTB_RS03145	COG3344	reverse transcriptase
BTB_RS03150	COG0156	8-amino-7-oxononanoate synthase activity
BTB_RS03155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTB_RS03165	COG4548	von Willebrand factor, type A
BTB_RS03170	COG0714	Associated with various cellular activities
BTB_RS03190	COG0531	amino acid
BTB_RS03195	COG2188	Transcriptional regulator
BTB_RS03200	COG1263	PTS System
BTB_RS03200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTB_RS03205	COG0366	Alpha amylase catalytic
BTB_RS03220	COG0697	spore germination
BTB_RS03230	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTB_RS03235	COG1115	amino acid carrier protein
BTB_RS03240	COG1126	abc transporter atp-binding protein
BTB_RS03245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTB_RS03250	COG0765	amino acid transport
BTB_RS03255	COG0765	amino acid transport
BTB_RS03260	COG0833	amino acid
BTB_RS03275	COG1595	DNA-templated transcription, initiation
BTB_RS03285	COG2378	regulation of single-species biofilm formation
BTB_RS03295	COG5002	protein histidine kinase activity
BTB_RS03320	COG0659	secondary active sulfate transmembrane transporter activity
BTB_RS03335	COG0747	negative chemotaxis
BTB_RS03345	COG0601	transmembrane transport
BTB_RS03350	COG4608	Belongs to the ABC transporter superfamily
BTB_RS03360	COG2271	Major facilitator Superfamily
BTB_RS03365	COG1846	Transcriptional regulator
BTB_RS03370	COG0477	Major facilitator Superfamily
BTB_RS03375	COG1609	Transcriptional regulator
BTB_RS03380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTB_RS03395	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTB_RS03400	COG1879	ABC-type sugar transport system periplasmic component
BTB_RS03420	COG1063	alcohol dehydrogenase
BTB_RS03450	COG1396	sequence-specific DNA binding
BTB_RS03490	COG5377	YqaJ viral recombinase family
BTB_RS03495	COG3723	Recombinational DNA repair protein, rece pathway
BTB_RS03510	COG1484	DNA-dependent DNA replication
BTB_RS03555	COG3617	BRO family, N-terminal domain
BTB_RS03580	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTB_RS03675	COG3409	Peptidoglycan-binding domain 1 protein
BTB_RS03675	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTB_RS03675	COG1388	LysM domain
BTB_RS03695	COG1674	ftsk spoiiie
BTB_RS03740	COG0840	transmembrane signaling receptor activity
BTB_RS03745	COG1388	LysM domain
BTB_RS03745	COG3584	3D domain protein
BTB_RS03750	COG1476	TRANSCRIPTIONal
BTB_RS03770	COG3104	oligopeptide transport
BTB_RS03775	COG1114	Component of the transport system for branched-chain amino acids
BTB_RS03790	COG1113	amino acid transport
BTB_RS03795	COG2252	PERMEase
BTB_RS03810	COG2153	protein acetylation
BTB_RS03820	COG0569	domain protein
BTB_RS03820	COG0475	glutathione-regulated potassium exporter activity
BTB_RS03830	COG1845	cytochrome c oxidase, subunit III
BTB_RS03835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTB_RS03845	COG0833	amino acid
BTB_RS03850	COG4990	cell redox homeostasis
BTB_RS03865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTB_RS03870	COG0697	spore germination
BTB_RS03875	COG0531	amino acid
BTB_RS03885	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTB_RS03890	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTB_RS03895	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTB_RS03895	COG1918	ferrous iron import across plasma membrane
BTB_RS03900	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BTB_RS03905	COG0573	inorganic phosphate transmembrane transporter activity
BTB_RS03910	COG0581	inorganic phosphate transmembrane transporter activity
BTB_RS03920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTB_RS04040	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BTB_RS04060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BTB_RS04065	COG1116	anion transmembrane transporter activity
BTB_RS04070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTB_RS04075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTB_RS04080	COG0352	thiamine-phosphate diphosphorylase activity
BTB_RS04085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTB_RS04090	COG2104	thiamine diphosphate biosynthetic process
BTB_RS04100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTB_RS04105	COG0351	phosphomethylpyrimidine kinase
BTB_RS04145	COG2205	protein histidine kinase activity
BTB_RS04150	COG2814	Major facilitator Superfamily
BTB_RS04155	COG1846	Transcriptional regulator
BTB_RS04170	COG2252	PERMEase
BTB_RS04175	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS04190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTB_RS04195	COG1621	beta-fructofuranosidase activity
BTB_RS04200	COG1263	PTS System
BTB_RS04200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTB_RS04205	COG1609	Transcriptional regulator
BTB_RS04260	COG0778	Nitroreductase
BTB_RS04265	COG2719	SpoVR family
BTB_RS04270	COG1414	Transcriptional regulator
BTB_RS04285	COG0446	pyridine nucleotide-disulphide oxidoreductase
BTB_RS04290	COG1937	Protein conserved in bacteria
BTB_RS04295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTB_RS04295	COG0425	Belongs to the sulfur carrier protein TusA family
BTB_RS04300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTB_RS04300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTB_RS04305	COG0425	Belongs to the sulfur carrier protein TusA family
BTB_RS04310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTB_RS04320	COG2210	Belongs to the sulfur carrier protein TusA family
BTB_RS04325	COG0730	response to heat
BTB_RS04335	COG1316	TRANSCRIPTIONal
BTB_RS04340	COG0604	alcohol dehydrogenase
BTB_RS04345	COG1283	sodium-dependent phosphate transmembrane transporter activity
BTB_RS04360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTB_RS04360	COG3711	transcriptional antiterminator
BTB_RS04365	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTB_RS04370	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTB_RS04390	COG3584	3D domain protein
BTB_RS04390	COG1388	LysM domain
BTB_RS04395	COG0577	efflux transmembrane transporter activity
BTB_RS04400	COG1136	(ABC) transporter
BTB_RS04410	COG5522	Integral membrane protein (intg_mem_TP0381)
BTB_RS04425	COG1114	Component of the transport system for branched-chain amino acids
BTB_RS04430	COG3546	catalase activity
BTB_RS04465	COG0586	Pfam SNARE associated Golgi protein
BTB_RS04500	COG0531	amino acid
BTB_RS04505	COG0475	glutathione-regulated potassium exporter activity
BTB_RS04515	COG1737	Transcriptional regulator
BTB_RS04525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTB_RS04525	COG1263	PTS System
BTB_RS04535	COG2259	Doxx family
BTB_RS04555	COG1522	sequence-specific DNA binding
BTB_RS04560	COG0165	Argininosuccinate lyase
BTB_RS04560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BTB_RS04565	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS04585	COG1309	transcriptional regulator
BTB_RS04590	COG2814	Major facilitator Superfamily
BTB_RS04595	COG1733	regulation of RNA biosynthetic process
BTB_RS04610	COG4533	DNA binding
BTB_RS04615	COG2211	Major facilitator Superfamily
BTB_RS04625	COG0693	protein deglycase activity
BTB_RS04630	COG0753	catalase activity
BTB_RS04630	COG0693	protein deglycase activity
BTB_RS04640	COG0531	amino acid
BTB_RS04655	COG1012	belongs to the aldehyde dehydrogenase family
BTB_RS04660	COG1132	(ABC) transporter
BTB_RS04665	COG1132	(ABC) transporter
BTB_RS04670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTB_RS04675	COG0765	amino acid transport
BTB_RS04680	COG1126	abc transporter atp-binding protein
BTB_RS04695	COG0189	ligase activity
BTB_RS04730	COG0028	Belongs to the TPP enzyme family
BTB_RS04750	COG0561	phosphatase activity
BTB_RS04760	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTB_RS04760	COG3409	Peptidoglycan-binding domain 1 protein
BTB_RS04765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTB_RS04770	COG0318	PFAM AMP-dependent synthetase and ligase
BTB_RS04785	COG0659	secondary active sulfate transmembrane transporter activity
BTB_RS04790	COG2244	polysaccharide biosynthetic process
BTB_RS04810	COG1024	Enoyl-CoA hydratase
BTB_RS04830	COG1363	Peptidase, m42
BTB_RS04870	COG0601	transmembrane transport
BTB_RS04875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTB_RS04880	COG0444	Belongs to the ABC transporter superfamily
BTB_RS04885	COG4608	Belongs to the ABC transporter superfamily
BTB_RS04910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTB_RS04925	COG0477	Major facilitator Superfamily
BTB_RS04930	COG3290	protein histidine kinase activity
BTB_RS04935	COG4565	transcriptional regulatory protein
BTB_RS04940	COG3181	Tripartite tricarboxylate transporter family receptor
BTB_RS04945	COG0494	nUDIX hydrolase
BTB_RS04960	COG0305	Participates in initiation and elongation during chromosome replication
BTB_RS04990	COG0477	Major facilitator Superfamily
BTB_RS05015	COG1073	alpha beta
BTB_RS05055	COG1183	phosphatidylcholine synthase activity
BTB_RS05065	COG2814	Major facilitator Superfamily
BTB_RS05070	COG0640	Transcriptional regulator
BTB_RS05080	COG2376	Dihydroxyacetone kinase
BTB_RS05135	COG0457	Tetratricopeptide repeat
BTB_RS05140	COG2373	Large extracellular alpha-helical protein
BTB_RS05170	COG0596	Alpha beta hydrolase
BTB_RS05195	COG3237	CsbD-like
BTB_RS05220	COG1191	sigma factor activity
BTB_RS05230	COG2208	phosphoserine phosphatase activity
BTB_RS05235	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTB_RS05240	COG2205	protein histidine kinase activity
BTB_RS05240	COG0784	Response regulator, receiver
BTB_RS05240	COG2198	Histidine kinase
BTB_RS05270	COG2801	Transposase and inactivated derivatives
BTB_RS05280	COG3344	reverse transcriptase
BTB_RS05290	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BTB_RS05310	COG0420	3'-5' exonuclease activity
BTB_RS05315	COG4717	serine-type aminopeptidase activity
BTB_RS05330	COG1280	lysine exporter protein (LysE YggA)
BTB_RS05335	COG0346	lactoylglutathione lyase activity
BTB_RS05340	COG0346	lactoylglutathione lyase activity
BTB_RS05350	COG0457	Tetratricopeptide repeat
BTB_RS05360	COG2267	carboxylic ester hydrolase activity
BTB_RS05385	COG2140	Oxalate decarboxylase
BTB_RS05390	COG3620	sequence-specific DNA binding
BTB_RS05395	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BTB_RS05400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BTB_RS05410	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BTB_RS05415	COG1695	Transcriptional regulator
BTB_RS05425	COG1595	DNA-templated transcription, initiation
BTB_RS05440	COG3973	AAA domain
BTB_RS05470	COG4980	gas vesicle protein
BTB_RS05475	COG0537	adenosine 5'-monophosphoramidase activity
BTB_RS05480	COG1131	(ABC) transporter
BTB_RS05485	COG4473	ABC transporter
BTB_RS05530	COG1309	transcriptional regulator
BTB_RS05540	COG3402	PFAM membrane-flanked domain
BTB_RS05545	COG3428	Bacterial PH domain
BTB_RS05590	COG0697	spore germination
BTB_RS05595	COG3402	PFAM membrane-flanked domain
BTB_RS05600	COG3428	Bacterial PH domain
BTB_RS05605	COG2329	Antibiotic biosynthesis monooxygenase
BTB_RS05610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTB_RS05625	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BTB_RS05660	COG1309	transcriptional regulator
BTB_RS05665	COG1511	domain protein
BTB_RS05685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTB_RS05690	COG1609	Transcriptional regulator
BTB_RS05700	COG1234	tRNA 3'-trailer cleavage
BTB_RS05705	COG0095	Lipoate-protein ligase
BTB_RS05715	COG0318	PFAM AMP-dependent synthetase and ligase
BTB_RS05725	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BTB_RS05735	COG4208	sulfate ABC transporter
BTB_RS05750	COG1408	metallophosphoesterase
BTB_RS05755	COG1078	dGTPase activity
BTB_RS05765	COG1595	DNA-templated transcription, initiation
BTB_RS05770	COG3708	Transcriptional regulator
BTB_RS05770	COG2207	Transcriptional regulator
BTB_RS05775	COG3547	Transposase (IS116 IS110 IS902 family)
BTB_RS05780	COG2205	protein histidine kinase activity
BTB_RS05785	COG0745	RESPONSE REGULATOR receiver
BTB_RS05805	COG0501	Belongs to the peptidase M48B family
BTB_RS05810	COG0840	transmembrane signaling receptor activity
BTB_RS05815	COG3693	PFAM glycoside hydrolase, family 10
BTB_RS05825	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BTB_RS05830	COG2224	Isocitrate lyase
BTB_RS05845	COG1278	Cold shock
BTB_RS05865	COG0398	Pfam SNARE associated Golgi protein
BTB_RS05885	COG0202	RNA polymerase activity
BTB_RS05925	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTB_RS05950	COG0367	asparagine synthase
BTB_RS05960	COG0753	catalase activity
BTB_RS05965	COG0004	ammonium transporteR
BTB_RS05985	COG2996	Protein conserved in bacteria
BTB_RS05995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTB_RS06010	COG0561	phosphatase activity
BTB_RS06030	COG2267	carboxylic ester hydrolase activity
BTB_RS06045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTB_RS06050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTB_RS06055	COG5504	Zn-dependent protease
BTB_RS06065	COG0180	Tryptophanyl-tRNA synthetase
BTB_RS06075	COG4166	transmembrane transport
BTB_RS06080	COG0601	transmembrane transport
BTB_RS06085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTB_RS06090	COG0444	Belongs to the ABC transporter superfamily
BTB_RS06095	COG4608	Belongs to the ABC transporter superfamily
BTB_RS06100	COG0534	Mate efflux family protein
BTB_RS06105	COG4166	transmembrane transport
BTB_RS06120	COG0861	Integral membrane protein TerC family
BTB_RS06130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTB_RS06140	COG1164	Oligoendopeptidase f
BTB_RS06150	COG2346	COG2346, Truncated hemoglobins
BTB_RS06155	COG4116	CYTH
BTB_RS06165	COG2357	RelA SpoT domain protein
BTB_RS06175	COG0564	pseudouridine synthase activity
BTB_RS06190	COG0772	Belongs to the SEDS family
BTB_RS06195	COG1216	Glycosyl transferase, family 2
BTB_RS06215	COG0463	Glycosyl transferase, family 2
BTB_RS06215	COG0457	Tetratricopeptide repeat
BTB_RS06235	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BTB_RS06250	COG1091	dTDP-4-dehydrorhamnose reductase activity
BTB_RS06295	COG2153	protein acetylation
BTB_RS06305	COG2382	esterase
BTB_RS06325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTB_RS06335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTB_RS06335	COG0512	Glutamine amidotransferase of anthranilate synthase
BTB_RS06370	COG1620	l-lactate permease
BTB_RS06375	COG5634	Uncharacterized conserved protein (DUF2278)
BTB_RS06390	COG4640	response to antibiotic
BTB_RS06415	COG2226	methyltransferase
BTB_RS06435	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTB_RS06445	COG1476	TRANSCRIPTIONal
BTB_RS06515	COG1686	Belongs to the peptidase S11 family
BTB_RS06520	COG0681	Belongs to the peptidase S26 family
BTB_RS06555	COG1012	belongs to the aldehyde dehydrogenase family
BTB_RS06565	COG1176	ABC-type spermidine putrescine transport system, permease component I
BTB_RS06570	COG1177	transmembrane transport
BTB_RS06585	COG2409	Drug exporters of the RND superfamily
BTB_RS06595	COG0564	pseudouridine synthase activity
BTB_RS06605	COG2340	Cysteine-rich secretory protein family
BTB_RS06610	COG0247	lactate metabolic process
BTB_RS06615	COG0277	FAD linked oxidase domain protein
BTB_RS06620	COG3835	regulator
BTB_RS06630	COG0745	RESPONSE REGULATOR receiver
BTB_RS06635	COG5002	protein histidine kinase activity
BTB_RS06640	COG2186	Transcriptional regulator
BTB_RS06660	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BTB_RS06670	COG2116	formate transmembrane transporter activity
BTB_RS06675	COG0861	Integral membrane protein TerC family
BTB_RS06680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTB_RS06690	COG2030	dehydratase
BTB_RS06710	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS06715	COG3243	poly(R)-hydroxyalkanoic acid synthase
BTB_RS06725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTB_RS06740	COG1840	ABC-type Fe3 transport system, periplasmic component
BTB_RS06745	COG3842	ATPase activity
BTB_RS06770	COG1349	DNA-binding transcription factor activity
BTB_RS06785	COG0235	Class ii aldolase
BTB_RS06795	COG2861	carbohydrate metabolic process
BTB_RS06805	COG3852	Histidine kinase
BTB_RS06810	COG1846	Transcriptional regulator
BTB_RS06820	COG2318	DinB family
BTB_RS06830	COG5002	protein histidine kinase activity
BTB_RS06840	COG0720	synthase
BTB_RS06855	COG4873	Protein conserved in bacteria
BTB_RS06885	COG1780	Probably involved in ribonucleotide reductase function
BTB_RS06890	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTB_RS06895	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTB_RS06900	COG1725	Transcriptional regulator
BTB_RS06905	COG1131	(ABC) transporter
BTB_RS06915	COG1131	(ABC) transporter
BTB_RS06935	COG1522	sequence-specific DNA binding
BTB_RS06945	COG1335	isochorismatase
BTB_RS06955	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTB_RS06960	COG2070	2-Nitropropane dioxygenase
BTB_RS06965	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BTB_RS06975	COG1696	Membrane protein involved in D-alanine export
BTB_RS07000	COG0716	FMN binding
BTB_RS07055	COG1846	Transcriptional regulator
BTB_RS07070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTB_RS07075	COG4709	membrane
BTB_RS07080	COG3874	Sporulation protein YtfJ
BTB_RS07100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTB_RS07105	COG0028	Belongs to the TPP enzyme family
BTB_RS07110	COG0440	acetolactate synthase activity
BTB_RS07185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTB_RS07200	COG1183	phosphatidylcholine synthase activity
BTB_RS07205	COG1368	sulfuric ester hydrolase activity
BTB_RS07215	COG0019	diaminopimelate decarboxylase activity
BTB_RS07235	COG0529	Catalyzes the synthesis of activated sulfate
BTB_RS07240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTB_RS07260	COG1648	precorrin-2 dehydrogenase activity
BTB_RS07265	COG0733	neurotransmitter:sodium symporter activity
BTB_RS07285	COG1757	Na H antiporter
BTB_RS07300	COG4758	membrane
BTB_RS07305	COG4585	Histidine kinase
BTB_RS07310	COG2197	response regulator
BTB_RS07320	COG1114	Component of the transport system for branched-chain amino acids
BTB_RS07330	COG2226	methyltransferase
BTB_RS07370	COG0730	response to heat
BTB_RS07375	COG0306	phosphate transporter
BTB_RS07380	COG1392	Phosphate transport regulator
BTB_RS07385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTB_RS07400	COG3852	Histidine kinase
BTB_RS07405	COG1801	Protein of unknown function DUF72
BTB_RS07415	COG0582	viral genome integration into host DNA
BTB_RS07420	COG5002	protein histidine kinase activity
BTB_RS07435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BTB_RS07435	COG0392	lysyltransferase activity
BTB_RS07450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTB_RS07455	COG1686	Belongs to the peptidase S11 family
BTB_RS07460	COG2715	membrane protein required for spore maturation
BTB_RS07465	COG0700	Nucleoside recognition
BTB_RS07470	COG1187	pseudouridine synthase activity
BTB_RS07480	COG1333	cytochrome c biogenesis protein
BTB_RS07485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTB_RS07490	COG0745	RESPONSE REGULATOR receiver
BTB_RS07495	COG5002	protein histidine kinase activity
BTB_RS07500	COG2096	Adenosyltransferase
BTB_RS07515	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BTB_RS07520	COG1141	Ferredoxin
BTB_RS07530	COG0514	ATP-dependent DNA helicase (RecQ)
BTB_RS07535	COG1266	CAAX protease self-immunity
BTB_RS07545	COG1408	metallophosphoesterase
BTB_RS07550	COG0789	Transcriptional regulator
BTB_RS07560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTB_RS07580	COG0492	ferredoxin-NADP+ reductase activity
BTB_RS07585	COG0252	asparaginase activity
BTB_RS07650	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTB_RS07665	COG0142	geranyltranstransferase activity
BTB_RS07675	COG0142	geranyltranstransferase activity
BTB_RS07700	COG0457	Tetratricopeptide repeat
BTB_RS07720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTB_RS07725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTB_RS07725	COG2010	Cytochrome c
BTB_RS07730	COG4347	Protein of unknown function (DUF1405)
BTB_RS07745	COG2738	Putative neutral zinc metallopeptidase
BTB_RS07755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTB_RS07760	COG1694	Mazg nucleotide pyrophosphohydrolase
BTB_RS07780	COG0438	transferase activity, transferring glycosyl groups
BTB_RS07815	COG1199	ATP-dependent helicase activity
BTB_RS07815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BTB_RS07835	COG3935	DnaD domain protein
BTB_RS07840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTB_RS07850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTB_RS07850	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTB_RS07900	COG0116	Belongs to the methyltransferase superfamily
BTB_RS07910	COG1199	ATP-dependent helicase activity
BTB_RS07915	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BTB_RS07925	COG0024	Methionine aminopeptidase
BTB_RS07935	COG2233	PERMEase
BTB_RS07940	COG2311	Membrane
BTB_RS07945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTB_RS07955	COG0456	acetyltransferase
BTB_RS07995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTB_RS08010	COG3944	biosynthesis protein
BTB_RS08020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTB_RS08035	COG1215	transferase activity, transferring glycosyl groups
BTB_RS08040	COG0438	transferase activity, transferring glycosyl groups
BTB_RS08055	COG0454	-acetyltransferase
BTB_RS08075	COG0328	RNA-DNA hybrid ribonuclease activity
BTB_RS08110	COG3403	YqcI/YcgG family
BTB_RS08115	COG1280	lysine exporter protein (LysE YggA)
BTB_RS08135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTB_RS08140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTB_RS08150	COG0475	glutathione-regulated potassium exporter activity
BTB_RS08155	COG0789	Transcriptional regulator
BTB_RS08155	COG4978	Transcriptional regulator
BTB_RS08165	COG2323	membrane
BTB_RS08170	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BTB_RS08230	COG1923	regulation of RNA biosynthetic process
BTB_RS08240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BTB_RS08245	COG1360	Flagellar Motor Protein
BTB_RS08250	COG2201	protein-glutamate methylesterase activity
BTB_RS08255	COG2198	Histidine kinase
BTB_RS08255	COG0643	Histidine kinase
BTB_RS08260	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTB_RS08260	COG1776	CheC inhibitor of MCP methylation
BTB_RS08275	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTB_RS08295	COG1256	bacterial-type flagellum assembly
BTB_RS08300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTB_RS08320	COG1815	bacterial-type flagellum-dependent cell motility
BTB_RS08325	COG1558	bacterial-type flagellum-dependent cell motility
BTB_RS08335	COG1766	The M ring may be actively involved in energy transduction
BTB_RS08340	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTB_RS08350	COG1157	protein secretion by the type III secretion system
BTB_RS08370	COG1749	Flagellar hook protein flgE
BTB_RS08385	COG0835	chemotaxis
BTB_RS08385	COG0784	Response regulator, receiver
BTB_RS08395	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTB_RS08400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTB_RS08405	COG0741	lytic transglycosylase activity
BTB_RS08415	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTB_RS08420	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTB_RS08420	COG1776	CheC inhibitor of MCP methylation
BTB_RS08430	COG1338	Plays a role in the flagellum-specific transport system
BTB_RS08435	COG1987	bacterial-type flagellum assembly
BTB_RS08445	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTB_RS08450	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTB_RS08455	COG1419	protein localization to endoplasmic reticulum
BTB_RS08460	COG4786	Flagellar basal body rod
BTB_RS08465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTB_RS08470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTB_RS08500	COG2329	Antibiotic biosynthesis monooxygenase
BTB_RS08530	COG0583	DNA-binding transcription factor activity
BTB_RS08535	COG3842	ATPase activity
BTB_RS08545	COG1177	transmembrane transport
BTB_RS08585	COG0406	alpha-ribazole phosphatase activity
BTB_RS08615	COG0367	asparagine synthase
BTB_RS08645	COG1802	Transcriptional regulator
BTB_RS08650	COG0697	spore germination
BTB_RS08660	COG0523	cobalamin synthesis protein
BTB_RS08665	COG0701	Predicted permease
BTB_RS08680	COG1757	Na H antiporter
BTB_RS08685	COG0789	Transcriptional regulator
BTB_RS08710	COG0534	Mate efflux family protein
BTB_RS08715	COG3340	Belongs to the peptidase S51 family
BTB_RS08735	COG0785	Cytochrome C biogenesis protein
BTB_RS08740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTB_RS08750	COG0457	Tetratricopeptide repeat
BTB_RS08770	COG2733	membrane
BTB_RS08805	COG1131	(ABC) transporter
BTB_RS08820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTB_RS08825	COG0528	UMP kinase activity
BTB_RS08835	COG1027	Aspartate ammonia-lyase
BTB_RS08840	COG0281	malic enzyme
BTB_RS08845	COG4191	Histidine kinase
BTB_RS08850	COG0784	Response regulator, receiver
BTB_RS08855	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTB_RS08915	COG1695	Transcriptional regulator
BTB_RS08925	COG0477	Major facilitator Superfamily
BTB_RS08940	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTB_RS08945	COG2223	nitrite transmembrane transporter activity
BTB_RS08950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTB_RS08970	COG0733	neurotransmitter:sodium symporter activity
BTB_RS08980	COG5566	PFAM Mor transcription activator
BTB_RS08985	COG2323	membrane
BTB_RS09005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTB_RS09015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTB_RS09020	COG0028	Belongs to the TPP enzyme family
BTB_RS09040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTB_RS09065	COG2814	Major facilitator Superfamily
BTB_RS09070	COG3384	dioxygenase
BTB_RS09080	COG3279	Response regulator of the LytR AlgR family
BTB_RS09085	COG0427	acetyl-CoA hydrolase
BTB_RS09105	COG2814	Major facilitator Superfamily
BTB_RS09110	COG1309	transcriptional regulator
BTB_RS09115	COG4166	transmembrane transport
BTB_RS09120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTB_RS09145	COG1914	H( )-stimulated, divalent metal cation uptake system
BTB_RS09160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTB_RS09170	COG0531	amino acid
BTB_RS09195	COG2309	aminopeptidase activity
BTB_RS09210	COG0456	acetyltransferase
BTB_RS09220	COG1266	CAAX protease self-immunity
BTB_RS09225	COG1309	transcriptional regulator
BTB_RS09230	COG2390	Transcriptional regulator
BTB_RS09240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTB_RS09245	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BTB_RS09255	COG4846	Membrane protein involved in cytochrome C biogenesis
BTB_RS09275	COG0583	DNA-binding transcription factor activity
BTB_RS09290	COG0006	proline dipeptidase activity
BTB_RS09300	COG2132	Multicopper oxidase
BTB_RS09310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTB_RS09330	COG1114	Component of the transport system for branched-chain amino acids
BTB_RS09340	COG1276	copper resistance
BTB_RS09340	COG2372	response to copper ion
BTB_RS09345	COG4549	nuclear export factor GLE1
BTB_RS09350	COG0697	spore germination
BTB_RS09355	COG0583	DNA-binding transcription factor activity
BTB_RS09360	COG1959	2 iron, 2 sulfur cluster binding
BTB_RS09365	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BTB_RS09370	COG0778	Nitroreductase
BTB_RS09380	COG0154	amidase activity
BTB_RS09385	COG1396	sequence-specific DNA binding
BTB_RS09405	COG3547	Transposase (IS116 IS110 IS902 family)
BTB_RS09475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTB_RS09475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTB_RS09560	COG2002	toxin-antitoxin pair type II binding
BTB_RS09595	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTB_RS09705	COG4824	toxin secretion phage lysis holin
BTB_RS09795	COG0628	permease
BTB_RS09805	COG1231	oxidoreductase activity
BTB_RS09810	COG0523	cobalamin synthesis protein
BTB_RS09820	COG0411	ABC transporter
BTB_RS09840	COG0583	DNA-binding transcription factor activity
BTB_RS09850	COG1942	4-Oxalocrotonate Tautomerase
BTB_RS09870	COG1271	oxidase subunit
BTB_RS09875	COG1294	oxidase, subunit
BTB_RS09880	COG4988	ABC transporter
BTB_RS09885	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BTB_RS09895	COG1216	Glycosyl transferase, family 2
BTB_RS09935	COG1686	Belongs to the peptidase S11 family
BTB_RS09950	COG0791	NLP P60 protein
BTB_RS09950	COG1388	LysM domain
BTB_RS09960	COG1132	(ABC) transporter
BTB_RS09965	COG0745	RESPONSE REGULATOR receiver
BTB_RS09970	COG5002	protein histidine kinase activity
BTB_RS09980	COG0300	oxidoreductase activity
BTB_RS09985	COG4122	O-methyltransferase activity
BTB_RS10015	COG0460	homoserine dehydrogenase
BTB_RS10040	COG1316	TRANSCRIPTIONal
BTB_RS10050	COG0745	RESPONSE REGULATOR receiver
BTB_RS10055	COG5002	protein histidine kinase activity
BTB_RS10070	COG1285	pathogenesis
BTB_RS10075	COG1247	-acetyltransferase
BTB_RS10095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTB_RS10105	COG1082	Xylose isomerase domain protein TIM barrel
BTB_RS10115	COG2814	Major facilitator Superfamily
BTB_RS10120	COG1279	arginine transmembrane transporter activity
BTB_RS10125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTB_RS10135	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTB_RS10170	COG0577	efflux transmembrane transporter activity
BTB_RS10175	COG2002	toxin-antitoxin pair type II binding
BTB_RS10180	COG1404	Belongs to the peptidase S8 family
BTB_RS10185	COG0640	Transcriptional regulator
BTB_RS10190	COG0667	Aldo Keto reductase
BTB_RS10195	COG2814	Major facilitator Superfamily
BTB_RS10220	COG0840	transmembrane signaling receptor activity
BTB_RS10235	COG3949	Membrane
BTB_RS10240	COG0783	Belongs to the Dps family
BTB_RS10255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTB_RS10265	COG1231	oxidoreductase activity
BTB_RS10270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTB_RS10275	COG4989	oxidoreductase activity
BTB_RS10280	COG0523	cobalamin synthesis protein
BTB_RS10285	COG0456	acetyltransferase
BTB_RS10290	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTB_RS10295	COG0702	epimerase
BTB_RS10315	COG4166	transmembrane transport
BTB_RS10340	COG5337	Spore coat protein CotH
BTB_RS10345	COG1051	belongs to the nudix hydrolase family
BTB_RS10350	COG0586	Pfam SNARE associated Golgi protein
BTB_RS10355	COG2244	polysaccharide biosynthetic process
BTB_RS10365	COG0701	Predicted permease
BTB_RS10370	COG3689	TIGRFAM TIGR03943 family protein
BTB_RS10375	COG1607	acyl-coa hydrolase
BTB_RS10380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTB_RS10395	COG0702	epimerase
BTB_RS10400	COG2839	Protein conserved in bacteria
BTB_RS10405	COG1253	flavin adenine dinucleotide binding
BTB_RS10430	COG1114	Component of the transport system for branched-chain amino acids
BTB_RS10435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTB_RS10450	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTB_RS10460	COG1876	peptidase activity
BTB_RS10475	COG2211	Major facilitator Superfamily
BTB_RS10500	COG0561	phosphatase activity
BTB_RS10505	COG1846	Transcriptional regulator
BTB_RS10510	COG2814	Major facilitator Superfamily
BTB_RS10520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTB_RS10525	COG4106	trans-aconitate 2-methyltransferase activity
BTB_RS10540	COG1819	glycosyl
BTB_RS10545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTB_RS10550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTB_RS10580	COG0456	acetyltransferase
BTB_RS10630	COG3874	Sporulation protein YtfJ
BTB_RS10655	COG2226	methyltransferase
BTB_RS10675	COG1082	Xylose isomerase domain protein TIM barrel
BTB_RS10680	COG0346	lactoylglutathione lyase activity
BTB_RS10690	COG0604	alcohol dehydrogenase
BTB_RS10695	COG1595	DNA-templated transcription, initiation
BTB_RS10710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTB_RS10710	COG0426	domain, Protein
BTB_RS10720	COG0386	Belongs to the glutathione peroxidase family
BTB_RS10725	COG1305	Transglutaminase-like
BTB_RS10730	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BTB_RS10735	COG0714	Associated with various cellular activities
BTB_RS10740	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BTB_RS10745	COG1140	nitrate reductase beta subunit
BTB_RS10750	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BTB_RS10755	COG2181	nitrate reductase activity
BTB_RS10760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTB_RS10765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTB_RS10770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTB_RS10775	COG0303	'Molybdopterin
BTB_RS10780	COG0314	molybdopterin synthase activity
BTB_RS10790	COG2223	nitrite transmembrane transporter activity
BTB_RS10805	COG1648	precorrin-2 dehydrogenase activity
BTB_RS10815	COG1587	Uroporphyrinogen-III synthase
BTB_RS10815	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BTB_RS10820	COG2146	nitrite reductase [NAD(P)H] activity
BTB_RS10825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTB_RS10830	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BTB_RS10865	COG2359	stage V sporulation protein S
BTB_RS10885	COG1418	mRNA catabolic process
BTB_RS10890	COG0488	(ABC) transporter
BTB_RS10905	COG0629	single-stranded DNA binding
BTB_RS10915	COG1413	lyase activity
BTB_RS10930	COG2136	Putative SAM-dependent methyltransferase
BTB_RS10930	COG2521	methyltransferase
BTB_RS10935	COG0018	arginyl-trna synthetase
BTB_RS10975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BTB_RS10980	COG0017	Asparaginyl-tRNA synthetase
BTB_RS11000	COG1674	ftsk spoiiie
BTB_RS11075	COG0733	neurotransmitter:sodium symporter activity
BTB_RS11100	COG2610	gluconate transmembrane transporter activity
BTB_RS11110	COG1794	racemase activity, acting on amino acids and derivatives
BTB_RS11120	COG0456	acetyltransferase
BTB_RS11130	COG3655	Transcriptional regulator
BTB_RS11135	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTB_RS11145	COG1131	(ABC) transporter
BTB_RS11150	COG4473	ABC transporter
BTB_RS11160	COG0546	phosphoglycolate phosphatase activity
BTB_RS11170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTB_RS11185	COG0768	penicillin binding
BTB_RS11195	COG0204	Acyl-transferase
BTB_RS11200	COG1272	protein, Hemolysin III
BTB_RS11210	COG0805	protein transport
BTB_RS11220	COG1307	EDD domain protein, DegV family
BTB_RS11230	COG1999	signal sequence binding
BTB_RS11235	COG0071	Belongs to the small heat shock protein (HSP20) family
BTB_RS11240	COG0367	asparagine synthase
BTB_RS11255	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTB_RS11260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTB_RS11265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTB_RS11285	COG1335	isochorismatase
BTB_RS11290	COG1051	belongs to the nudix hydrolase family
BTB_RS11295	COG0668	transmembrane transport
BTB_RS11300	COG4585	Histidine kinase
BTB_RS11300	COG2203	Gaf domain
BTB_RS11305	COG2197	response regulator
BTB_RS11310	COG1737	Transcriptional regulator
BTB_RS11315	COG0384	phenazine biosynthesis protein PhzF
BTB_RS11320	COG1064	alcohol dehydrogenase
BTB_RS11345	COG1070	Carbohydrate kinase
BTB_RS11355	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BTB_RS11390	COG1125	glycine betaine transport
BTB_RS11390	COG0517	IMP dehydrogenase activity
BTB_RS11395	COG1174	glycine betaine transport
BTB_RS11430	COG1253	flavin adenine dinucleotide binding
BTB_RS11435	COG1012	belongs to the aldehyde dehydrogenase family
BTB_RS11440	COG5506	Protein of unknown function (DUF1694)
BTB_RS11455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTB_RS11460	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BTB_RS11465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BTB_RS11470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTB_RS11475	COG0456	acetyltransferase
BTB_RS11480	COG3829	transcription factor binding
BTB_RS11485	COG1509	lysine 2,3-aminomutase activity
BTB_RS11515	COG3064	Membrane
BTB_RS11515	COG4991	sh3 domain protein
BTB_RS11515	COG0515	serine threonine protein kinase
BTB_RS11525	COG0671	phosphoesterase, PA-phosphatase related
BTB_RS11530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTB_RS11535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTB_RS11605	COG0300	oxidoreductase activity
BTB_RS11625	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTB_RS11625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTB_RS11635	COG2814	Major facilitator Superfamily
BTB_RS11640	COG4841	protein insertion into membrane
BTB_RS11645	COG0372	Belongs to the citrate synthase family
BTB_RS11650	COG2079	MmgE PrpD family protein
BTB_RS11655	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BTB_RS11660	COG1960	acyl-CoA dehydrogenase activity
BTB_RS11665	COG2084	Dehydrogenase
BTB_RS11675	COG1280	lysine exporter protein (LysE YggA)
BTB_RS11680	COG1024	Enoyl-CoA hydratase
BTB_RS11695	COG0420	3'-5' exonuclease activity
BTB_RS11700	COG0419	ATPase involved in DNA repair
BTB_RS11720	COG2223	nitrite transmembrane transporter activity
BTB_RS11725	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS11730	COG1169	isochorismate synthase
BTB_RS11735	COG1021	2,3-dihydroxybenzoate-AMP ligase
BTB_RS11740	COG3433	isochorismatase activity
BTB_RS11740	COG1535	isochorismatase
BTB_RS11745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BTB_RS11750	COG3251	PFAM MbtH domain protein
BTB_RS11755	COG2814	Major facilitator Superfamily
BTB_RS11770	COG0776	regulation of translation
BTB_RS11780	COG2318	DinB family
BTB_RS11790	COG1115	amino acid carrier protein
BTB_RS11810	COG1187	pseudouridine synthase activity
BTB_RS11815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTB_RS11820	COG1136	(ABC) transporter
BTB_RS11830	COG2814	Major facilitator Superfamily
BTB_RS11845	COG0028	Belongs to the TPP enzyme family
BTB_RS11855	COG1234	tRNA 3'-trailer cleavage
BTB_RS11880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTB_RS11895	COG1846	Transcriptional regulator
BTB_RS11905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTB_RS11940	COG1247	-acetyltransferase
BTB_RS11965	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BTB_RS11975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTB_RS12005	COG0583	DNA-binding transcription factor activity
BTB_RS12010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTB_RS12030	COG0583	DNA-binding transcription factor activity
BTB_RS12035	COG2258	MOSC domain
BTB_RS12050	COG1132	(ABC) transporter
BTB_RS12055	COG1132	(ABC) transporter
BTB_RS12095	COG0582	viral genome integration into host DNA
BTB_RS12125	COG5484	DNA packaging
BTB_RS12140	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTB_RS12170	COG1396	sequence-specific DNA binding
BTB_RS12200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTB_RS12205	COG1595	DNA-templated transcription, initiation
BTB_RS12230	COG1649	PFAM Uncharacterised BCR, COG1649
BTB_RS12255	COG2971	BadF BadG BcrA BcrD
BTB_RS12275	COG1846	Transcriptional regulator
BTB_RS12290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTB_RS12325	COG3615	Tellurite resistance protein tehB
BTB_RS12325	COG0500	methyltransferase
BTB_RS12335	COG2226	methyltransferase
BTB_RS12340	COG3961	Belongs to the TPP enzyme family
BTB_RS12345	COG1846	Transcriptional regulator
BTB_RS12380	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTB_RS12410	COG2002	toxin-antitoxin pair type II binding
BTB_RS12420	COG0730	response to heat
BTB_RS12425	COG0110	maltose O-acetyltransferase activity
BTB_RS12430	COG1686	Belongs to the peptidase S11 family
BTB_RS12445	COG2814	Major facilitator Superfamily
BTB_RS12480	COG1115	amino acid carrier protein
BTB_RS12485	COG2066	Belongs to the glutaminase family
BTB_RS12490	COG4191	Histidine kinase
BTB_RS12495	COG0784	Response regulator, receiver
BTB_RS12500	COG0697	spore germination
BTB_RS12505	COG0531	amino acid
BTB_RS12515	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTB_RS12520	COG0531	amino acid
BTB_RS12525	COG0322	excinuclease ABC activity
BTB_RS12530	COG2207	Transcriptional regulator
BTB_RS12555	COG5002	protein histidine kinase activity
BTB_RS12565	COG2267	carboxylic ester hydrolase activity
BTB_RS12620	COG3547	Transposase (IS116 IS110 IS902 family)
BTB_RS12630	COG0768	penicillin binding
BTB_RS12635	COG1595	DNA-templated transcription, initiation
BTB_RS12645	COG0768	penicillin binding
BTB_RS12650	COG0768	penicillin binding
BTB_RS12665	COG1408	metallophosphoesterase
BTB_RS12675	COG1131	(ABC) transporter
BTB_RS12685	COG1309	transcriptional regulator
BTB_RS12700	COG1960	acyl-CoA dehydrogenase activity
BTB_RS12705	COG0439	Biotin carboxylase
BTB_RS12710	COG0511	ligase activity, forming carbon-carbon bonds
BTB_RS12715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTB_RS12720	COG1024	Enoyl-CoA hydratase
BTB_RS12725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BTB_RS12730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTB_RS12740	COG3547	Transposase (IS116 IS110 IS902 family)
BTB_RS12765	COG1686	Belongs to the peptidase S11 family
BTB_RS12790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTB_RS12805	COG3227	Zinc metalloprotease (Elastase)
BTB_RS12850	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS12870	COG1733	regulation of RNA biosynthetic process
BTB_RS12910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTB_RS12920	COG2368	4-hydroxyphenylacetate
BTB_RS12935	COG1063	alcohol dehydrogenase
BTB_RS12945	COG2323	membrane
BTB_RS12955	COG0693	protein deglycase activity
BTB_RS12965	COG3386	PFAM SMP-30 Gluconolaconase
BTB_RS12970	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BTB_RS12975	COG3773	Cell wall hydrolase
BTB_RS12985	COG0745	RESPONSE REGULATOR receiver
BTB_RS12990	COG2205	protein histidine kinase activity
BTB_RS13005	COG0488	(ABC) transporter
BTB_RS13020	COG1136	(ABC) transporter
BTB_RS13025	COG0577	efflux transmembrane transporter activity
BTB_RS13045	COG0460	homoserine dehydrogenase
BTB_RS13050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTB_RS13060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BTB_RS13085	COG0582	viral genome integration into host DNA
BTB_RS13140	COG1484	DNA-dependent DNA replication
BTB_RS13160	COG2002	toxin-antitoxin pair type II binding
BTB_RS13170	COG2002	toxin-antitoxin pair type II binding
BTB_RS13230	COG0582	viral genome integration into host DNA
BTB_RS13265	COG5484	DNA packaging
BTB_RS13280	COG0740	serine-type endopeptidase activity
BTB_RS13340	COG3547	Transposase (IS116 IS110 IS902 family)
BTB_RS13405	COG2124	cytochrome p450
BTB_RS13440	COG0561	phosphatase activity
BTB_RS13445	COG5002	protein histidine kinase activity
BTB_RS13450	COG0768	penicillin binding
BTB_RS13460	COG1819	glycosyl
BTB_RS13465	COG1794	racemase activity, acting on amino acids and derivatives
BTB_RS13485	COG2205	protein histidine kinase activity
BTB_RS13545	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTB_RS13550	COG0604	alcohol dehydrogenase
BTB_RS13555	COG0671	phosphoesterase, PA-phosphatase related
BTB_RS13560	COG0768	penicillin binding
BTB_RS13610	COG0789	Transcriptional regulator
BTB_RS13615	COG2814	Major facilitator Superfamily
BTB_RS13630	COG0584	glycerophosphoryl diester phosphodiesterase
BTB_RS13650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTB_RS13655	COG0697	spore germination
BTB_RS13690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTB_RS13700	COG2223	nitrite transmembrane transporter activity
BTB_RS13715	COG0592	DNA-directed DNA polymerase activity
BTB_RS13750	COG3878	Protein conserved in bacteria
BTB_RS13775	COG4667	esterase of the alpha-beta hydrolase superfamily
BTB_RS13815	COG0322	excinuclease ABC activity
BTB_RS13855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTB_RS13885	COG1011	Hydrolase
BTB_RS13890	COG0745	RESPONSE REGULATOR receiver
BTB_RS13895	COG5002	protein histidine kinase activity
BTB_RS13910	COG1522	sequence-specific DNA binding
BTB_RS13925	COG1136	(ABC) transporter
BTB_RS13930	COG0577	efflux transmembrane transporter activity
BTB_RS13935	COG1073	alpha beta
BTB_RS13940	COG0657	acetylesterase activity
BTB_RS13945	COG0076	glutamate decarboxylase activity
BTB_RS13960	COG1523	belongs to the glycosyl hydrolase 13 family
BTB_RS13965	COG3227	Zinc metalloprotease (Elastase)
BTB_RS13970	COG0737	Belongs to the 5'-nucleotidase family
BTB_RS13985	COG0201	protein transport
BTB_RS14000	COG0697	spore germination
BTB_RS14005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTB_RS14015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTB_RS14045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTB_RS14060	COG2959	enzyme of heme biosynthesis
BTB_RS14100	COG1309	transcriptional regulator
BTB_RS14125	COG3284	Transcriptional regulator
BTB_RS14145	COG1349	DNA-binding transcription factor activity
BTB_RS14160	COG1959	2 iron, 2 sulfur cluster binding
BTB_RS14175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTB_RS14180	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTB_RS14185	COG0022	dehydrogenase e1 component
BTB_RS14190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTB_RS14200	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS14205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTB_RS14205	COG0456	acetyltransferase
BTB_RS14240	COG4176	ABC-type proline glycine betaine transport system permease component
BTB_RS14245	COG0517	IMP dehydrogenase activity
BTB_RS14245	COG4175	Glycine betaine
BTB_RS14275	COG2153	protein acetylation
BTB_RS14280	COG3397	chitin binding
BTB_RS14285	COG1819	glycosyl
BTB_RS14300	COG2205	protein histidine kinase activity
BTB_RS14310	COG2315	Protein conserved in bacteria
BTB_RS14360	COG0456	acetyltransferase
BTB_RS14365	COG3973	AAA domain
BTB_RS14375	COG2801	Transposase and inactivated derivatives
BTB_RS14395	COG0514	ATP-dependent DNA helicase (RecQ)
BTB_RS14425	COG4637	Psort location Cytoplasmic, score
BTB_RS14445	COG3397	chitin binding
BTB_RS14460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTB_RS14465	COG1115	amino acid carrier protein
BTB_RS14470	COG1012	belongs to the aldehyde dehydrogenase family
BTB_RS14475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTB_RS14485	COG3938	Belongs to the proline racemase family
BTB_RS14490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTB_RS14535	COG1078	dGTPase activity
BTB_RS14540	COG0586	Pfam SNARE associated Golgi protein
BTB_RS14550	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BTB_RS14560	COG4166	transmembrane transport
BTB_RS14570	COG4948	Mandelate Racemase Muconate Lactonizing
BTB_RS14585	COG0667	Aldo Keto reductase
BTB_RS14625	COG3850	Histidine kinase
BTB_RS14625	COG5002	protein histidine kinase activity
BTB_RS14630	COG0745	RESPONSE REGULATOR receiver
BTB_RS14665	COG1164	Oligoendopeptidase f
BTB_RS14670	COG1307	EDD domain protein, DegV family
BTB_RS14695	COG2814	Major facilitator Superfamily
BTB_RS14705	COG1664	Polymer-forming cytoskeletal
BTB_RS14710	COG0789	Transcriptional regulator
BTB_RS14715	COG4533	DNA binding
BTB_RS14720	COG0477	Major facilitator Superfamily
BTB_RS14720	COG2814	Major facilitator Superfamily
BTB_RS14745	COG2261	transglycosylase associated protein
BTB_RS14765	COG2226	methyltransferase
BTB_RS14800	COG0436	Aminotransferase
BTB_RS14805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTB_RS14815	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BTB_RS14830	COG1131	(ABC) transporter
BTB_RS14875	COG0628	permease
BTB_RS14890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTB_RS14895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTB_RS14935	COG2746	aminoglycoside 3-N-acetyltransferase activity
BTB_RS14945	COG0697	spore germination
BTB_RS14955	COG2318	DinB family
BTB_RS14980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTB_RS14985	COG0346	lactoylglutathione lyase activity
BTB_RS14990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTB_RS15010	COG0861	Integral membrane protein TerC family
BTB_RS15015	COG1368	sulfuric ester hydrolase activity
BTB_RS15020	COG0488	(ABC) transporter
BTB_RS15030	COG1309	transcriptional regulator
BTB_RS15045	COG0287	Prephenate dehydrogenase
BTB_RS15060	COG1605	Chorismate mutase
BTB_RS15060	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTB_RS15105	COG3584	3D domain protein
BTB_RS15105	COG1388	LysM domain
BTB_RS15115	COG0277	FAD linked oxidase domain protein
BTB_RS15140	COG1879	ABC-type sugar transport system periplasmic component
BTB_RS15145	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTB_RS15150	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTB_RS15160	COG1129	ABC transporter
BTB_RS15165	COG2390	Transcriptional regulator
BTB_RS15170	COG1070	Carbohydrate kinase
BTB_RS15190	COG2329	Antibiotic biosynthesis monooxygenase
BTB_RS15200	COG0640	Transcriptional regulator
BTB_RS15205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTB_RS15220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTB_RS15225	COG4187	Peptidase family M20/M25/M40
BTB_RS15230	COG1414	Transcriptional regulator
BTB_RS15235	COG0833	amino acid
BTB_RS15255	COG0825	malonyl-CoA metabolic process
BTB_RS15265	COG3239	Fatty acid desaturase
BTB_RS15275	COG2720	vancomycin resistance protein
BTB_RS15280	COG1785	Belongs to the alkaline phosphatase family
BTB_RS15290	COG3655	Transcriptional regulator
BTB_RS15310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTB_RS15315	COG0346	lactoylglutathione lyase activity
BTB_RS15340	COG0714	Associated with various cellular activities
BTB_RS15360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTB_RS15365	COG0753	catalase activity
BTB_RS15400	COG0778	Nitroreductase
BTB_RS15405	COG1846	Transcriptional regulator
BTB_RS15425	COG4884	unkown
BTB_RS15425	COG3831	ATPase activity
BTB_RS15460	COG0456	acetyltransferase
BTB_RS15475	COG0697	spore germination
BTB_RS15480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTB_RS15525	COG0730	response to heat
BTB_RS15535	COG0833	amino acid
BTB_RS15545	COG4335	DNA alkylation repair
BTB_RS15555	COG5002	protein histidine kinase activity
BTB_RS15560	COG0745	RESPONSE REGULATOR receiver
BTB_RS15570	COG1136	(ABC) transporter
BTB_RS15570	COG0577	efflux transmembrane transporter activity
BTB_RS15605	COG0768	penicillin binding
BTB_RS15635	COG1984	allophanate hydrolase subunit 2
BTB_RS15640	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BTB_RS15645	COG1414	Transcriptional regulator
BTB_RS15660	COG3142	Participates in the control of copper homeostasis
BTB_RS15665	COG0640	Transcriptional regulator
BTB_RS15675	COG1960	acyl-CoA dehydrogenase activity
BTB_RS15690	COG3314	Sporulation integral membrane protein YlbJ
BTB_RS15710	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BTB_RS15750	COG2267	carboxylic ester hydrolase activity
BTB_RS15755	COG1335	isochorismatase
BTB_RS15775	COG0583	DNA-binding transcription factor activity
BTB_RS15780	COG1846	Transcriptional regulator
BTB_RS15785	COG0598	Magnesium transport protein CorA
BTB_RS15830	COG0814	amino acid
BTB_RS15855	COG0415	Belongs to the DNA photolyase family
BTB_RS15860	COG0288	reversible hydration of carbon dioxide
BTB_RS15870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTB_RS15875	COG5609	conserved protein (DUF2294)
BTB_RS15890	COG0456	acetyltransferase
BTB_RS15895	COG1575	Belongs to the MenA family. Type 1 subfamily
BTB_RS15905	COG0798	PFAM Bile acid sodium symporter
BTB_RS15910	COG0346	lactoylglutathione lyase activity
BTB_RS15915	COG0640	Transcriptional regulator
BTB_RS15925	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BTB_RS15935	COG3320	Male sterility
BTB_RS15935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTB_RS15940	COG1309	transcriptional regulator
BTB_RS15990	COG2814	Major facilitator Superfamily
BTB_RS15995	COG1309	transcriptional regulator
BTB_RS16000	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS16005	COG1522	sequence-specific DNA binding
BTB_RS16020	COG0346	lactoylglutathione lyase activity
BTB_RS16085	COG3547	Transposase (IS116 IS110 IS902 family)
BTB_RS16100	COG0745	RESPONSE REGULATOR receiver
BTB_RS16105	COG5002	protein histidine kinase activity
BTB_RS16105	COG3850	Histidine kinase
BTB_RS16145	COG1136	(ABC) transporter
BTB_RS16185	COG2814	Major facilitator Superfamily
BTB_RS16205	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BTB_RS16230	COG1690	Belongs to the RtcB family
BTB_RS16240	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BTB_RS16255	COG0277	FAD linked oxidase domain protein
BTB_RS16265	COG0577	efflux transmembrane transporter activity
BTB_RS16285	COG3850	Histidine kinase
BTB_RS16285	COG5002	protein histidine kinase activity
BTB_RS16295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTB_RS16310	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTB_RS16330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTB_RS16350	COG0662	Cupin 2, conserved barrel domain protein
BTB_RS16355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTB_RS16355	COG2207	Transcriptional regulator
BTB_RS16370	COG3409	Peptidoglycan-binding domain 1 protein
BTB_RS16370	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTB_RS16390	COG1876	peptidase activity
BTB_RS16395	COG2843	Capsule synthesis protein
BTB_RS16405	COG0477	Major facilitator Superfamily
BTB_RS16420	COG1846	Transcriptional regulator
BTB_RS16425	COG2814	Major facilitator Superfamily
BTB_RS16450	COG2031	fatty acid transporter
BTB_RS16460	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTB_RS16515	COG1288	antiporter activity
BTB_RS16520	COG2356	endonuclease I
BTB_RS16530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTB_RS16540	COG3620	sequence-specific DNA binding
BTB_RS16555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BTB_RS16575	COG1733	regulation of RNA biosynthetic process
BTB_RS16580	COG0778	Nitroreductase
BTB_RS16610	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS16620	COG1131	(ABC) transporter
BTB_RS16645	COG1011	Hydrolase
BTB_RS16655	COG2365	Tyrosine phosphatase family
BTB_RS16680	COG0346	lactoylglutathione lyase activity
BTB_RS16685	COG1940	carbohydrate kinase activity
BTB_RS16695	COG0110	maltose O-acetyltransferase activity
BTB_RS16710	COG0628	permease
BTB_RS16735	COG0500	methyltransferase
BTB_RS16745	COG0477	Major facilitator Superfamily
BTB_RS16770	COG1253	flavin adenine dinucleotide binding
BTB_RS16775	COG0789	Transcriptional regulator
BTB_RS16785	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTB_RS16810	COG0697	spore germination
BTB_RS16820	COG1357	PFAM Pentapeptide repeats (8 copies)
BTB_RS16825	COG3813	Protein conserved in bacteria
BTB_RS16830	COG2706	6-phosphogluconolactonase activity
BTB_RS16835	COG1070	Carbohydrate kinase
BTB_RS16850	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BTB_RS16855	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BTB_RS16860	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTB_RS16865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTB_RS16870	COG0604	alcohol dehydrogenase
BTB_RS16875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTB_RS16885	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS16900	COG0840	transmembrane signaling receptor activity
BTB_RS16910	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTB_RS16910	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTB_RS16915	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTB_RS16915	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTB_RS16920	COG1733	regulation of RNA biosynthetic process
BTB_RS16935	COG0656	L-ascorbic acid biosynthetic process
BTB_RS16940	COG2814	Major facilitator Superfamily
BTB_RS16960	COG2824	Alkylphosphonate utilization operon protein PhnA
BTB_RS16965	COG0659	secondary active sulfate transmembrane transporter activity
BTB_RS16980	COG0814	amino acid
BTB_RS17015	COG1733	regulation of RNA biosynthetic process
BTB_RS17020	COG2188	Transcriptional regulator
BTB_RS17030	COG0673	inositol 2-dehydrogenase activity
BTB_RS17035	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BTB_RS17040	COG1733	regulation of RNA biosynthetic process
BTB_RS17045	COG1733	regulation of RNA biosynthetic process
BTB_RS17070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTB_RS17095	COG0384	phenazine biosynthesis protein PhzF
BTB_RS17105	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS17115	COG0318	PFAM AMP-dependent synthetase and ligase
BTB_RS17120	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTB_RS17125	COG1733	regulation of RNA biosynthetic process
BTB_RS17135	COG0726	polysaccharide deacetylase
BTB_RS17145	COG1191	sigma factor activity
BTB_RS17155	COG1280	lysine exporter protein (LysE YggA)
BTB_RS17205	COG1151	hydroxylamine reductase activity
BTB_RS17215	COG3409	Peptidoglycan-binding domain 1 protein
BTB_RS17215	COG3757	hydrolase, family 25
BTB_RS17250	COG2072	flavoprotein involved in K transport
BTB_RS17285	COG1113	amino acid transport
BTB_RS17290	COG2814	Major facilitator Superfamily
BTB_RS17320	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BTB_RS17325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTB_RS17340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTB_RS17345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTB_RS17350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTB_RS17355	COG3739	integral membrane protein
BTB_RS17385	COG0583	DNA-binding transcription factor activity
BTB_RS17405	COG1193	negative regulation of DNA recombination
BTB_RS17420	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BTB_RS17425	COG1164	Oligoendopeptidase f
BTB_RS17445	COG3781	membrane
BTB_RS17460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTB_RS17485	COG0584	glycerophosphoryl diester phosphodiesterase
BTB_RS17500	COG0640	Transcriptional regulator
BTB_RS17505	COG0604	alcohol dehydrogenase
BTB_RS17515	COG0457	Tetratricopeptide repeat
BTB_RS17525	COG2808	Putative FMN-binding domain
BTB_RS17530	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTB_RS17540	COG0277	FAD linked oxidase domain protein
BTB_RS17565	COG0823	Involved in the tonB-independent uptake of proteins
BTB_RS17570	COG3397	chitin binding
BTB_RS17580	COG0697	spore germination
BTB_RS17625	COG0488	(ABC) transporter
BTB_RS17630	COG1309	transcriptional regulator
BTB_RS17645	COG1876	peptidase activity
BTB_RS17670	COG3852	Histidine kinase
BTB_RS17680	COG1285	pathogenesis
BTB_RS17695	COG2514	catechol 2,3-dioxygenase activity
BTB_RS17700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTB_RS17705	COG1126	abc transporter atp-binding protein
BTB_RS17710	COG0765	amino acid transport
BTB_RS17715	COG2720	vancomycin resistance protein
BTB_RS17750	COG0716	FMN binding
BTB_RS17760	COG1051	belongs to the nudix hydrolase family
BTB_RS17780	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS17790	COG0165	Argininosuccinate lyase
BTB_RS17805	COG4145	pantothenate transmembrane transporter activity
BTB_RS17815	COG1012	belongs to the aldehyde dehydrogenase family
BTB_RS17820	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS17830	COG1657	PFAM Prenyltransferase squalene oxidase
BTB_RS17835	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BTB_RS17840	COG2962	Rard protein
BTB_RS17845	COG3326	Membrane
BTB_RS17860	COG0489	protein tyrosine kinase activity
BTB_RS17870	COG0314	molybdopterin synthase activity
BTB_RS17875	COG0303	'Molybdopterin
BTB_RS17880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTB_RS17885	COG2116	formate transmembrane transporter activity
BTB_RS17895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTB_RS17900	COG5609	conserved protein (DUF2294)
BTB_RS17905	COG2427	Protein of unknown function (DUF1641)
BTB_RS17910	COG3383	formate dehydrogenase (NAD+) activity
BTB_RS17920	COG0697	spore germination
BTB_RS17935	COG0531	amino acid
BTB_RS17970	COG2226	methyltransferase
BTB_RS17975	COG4166	transmembrane transport
BTB_RS17980	COG2801	Transposase and inactivated derivatives
BTB_RS17990	COG4166	transmembrane transport
BTB_RS17995	COG4166	transmembrane transport
BTB_RS18000	COG1316	TRANSCRIPTIONal
BTB_RS18020	COG1131	(ABC) transporter
BTB_RS18040	COG0673	inositol 2-dehydrogenase activity
BTB_RS18045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTB_RS18050	COG0187	DNA topoisomerase II activity
BTB_RS18055	COG1832	CoA-binding protein
BTB_RS18060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTB_RS18065	COG0745	RESPONSE REGULATOR receiver
BTB_RS18075	COG1328	CTP reductase activity
BTB_RS18075	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BTB_RS18085	COG4841	protein insertion into membrane
BTB_RS18090	COG0824	Thioesterase
BTB_RS18120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTB_RS18130	COG2274	protein secretion by the type I secretion system
BTB_RS18135	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTB_RS18165	COG2211	Major facilitator Superfamily
BTB_RS18175	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTB_RS18190	COG0183	Belongs to the thiolase family
BTB_RS18195	COG0318	PFAM AMP-dependent synthetase and ligase
BTB_RS18200	COG1268	BioY protein
BTB_RS18205	COG0318	PFAM AMP-dependent synthetase and ligase
BTB_RS18210	COG1396	sequence-specific DNA binding
BTB_RS18245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTB_RS18255	COG5002	protein histidine kinase activity
BTB_RS18260	COG0400	carboxylic ester hydrolase activity
BTB_RS18265	COG0346	lactoylglutathione lyase activity
BTB_RS18270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTB_RS18275	COG0069	glutamate synthase activity
BTB_RS18280	COG1902	pentaerythritol trinitrate reductase activity
BTB_RS18285	COG1329	Transcriptional regulator
BTB_RS18290	COG0010	Belongs to the arginase family
BTB_RS18315	COG2226	methyltransferase
BTB_RS18340	COG4846	Membrane protein involved in cytochrome C biogenesis
BTB_RS18345	COG0785	Cytochrome C biogenesis protein
BTB_RS18355	COG1473	amidohydrolase
BTB_RS18365	COG1131	(ABC) transporter
BTB_RS18380	COG0583	DNA-binding transcription factor activity
BTB_RS18390	COG1346	cytolysis
BTB_RS18405	COG0730	response to heat
BTB_RS18435	COG1132	(ABC) transporter
BTB_RS18440	COG1132	(ABC) transporter
BTB_RS18475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTB_RS18490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTB_RS18510	COG1695	Transcriptional regulator
BTB_RS18515	COG0174	glutamine synthetase
BTB_RS18520	COG0789	Transcriptional regulator
BTB_RS18525	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BTB_RS18530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTB_RS18535	COG2860	membrane
BTB_RS18545	COG0464	growth
BTB_RS18560	COG2801	Transposase and inactivated derivatives
BTB_RS18585	COG1388	LysM domain
BTB_RS18585	COG3584	3D domain protein
BTB_RS18590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTB_RS18590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTB_RS18590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTB_RS18595	COG1105	Belongs to the carbohydrate kinase PfkB family
BTB_RS18600	COG1349	DNA-binding transcription factor activity
BTB_RS18605	COG1979	alcohol dehydrogenase
BTB_RS18610	COG2322	membrane
BTB_RS18625	COG1113	amino acid transport
BTB_RS18635	COG1408	metallophosphoesterase
BTB_RS18640	COG2116	formate transmembrane transporter activity
BTB_RS18655	COG2217	Heavy metal translocating P-type atpase
BTB_RS18660	COG2608	mercury ion transmembrane transporter activity
BTB_RS18665	COG1937	Protein conserved in bacteria
BTB_RS18685	COG2819	hydrolase of the alpha beta superfamily
BTB_RS18690	COG1120	ATPase activity
BTB_RS18695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTB_RS18700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTB_RS18705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTB_RS18710	COG0708	Exodeoxyribonuclease III
BTB_RS18715	COG2169	Transcriptional regulator
BTB_RS18720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTB_RS18725	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BTB_RS18735	COG2364	Membrane
BTB_RS18750	COG2267	carboxylic ester hydrolase activity
BTB_RS18755	COG5001	Diguanylate cyclase
BTB_RS18755	COG3300	MHYT domain
BTB_RS18775	COG1086	Polysaccharide biosynthesis protein
BTB_RS18790	COG1346	cytolysis
BTB_RS18800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTB_RS18810	COG2188	Transcriptional regulator
BTB_RS18815	COG2723	6-phospho-beta-galactosidase activity
BTB_RS18825	COG1404	Belongs to the peptidase S8 family
BTB_RS18830	COG3773	Cell wall hydrolase
BTB_RS18840	COG1368	sulfuric ester hydrolase activity
BTB_RS18845	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTB_RS18870	COG4550	Control of competence regulator ComK, YlbF/YmcA
BTB_RS18880	COG1013	pyruvate-flavodoxin oxidoreductase activity
BTB_RS18885	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BTB_RS18885	COG0674	pyruvate-flavodoxin oxidoreductase activity
BTB_RS18895	COG2359	stage V sporulation protein S
BTB_RS18900	COG1692	metallophosphoesterase
BTB_RS18925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTB_RS18930	COG1426	Protein conserved in bacteria
BTB_RS18945	COG0300	oxidoreductase activity
BTB_RS18950	COG0612	Peptidase, M16
BTB_RS18955	COG0612	Peptidase, M16
BTB_RS18960	COG1079	Belongs to the binding-protein-dependent transport system permease family
BTB_RS18965	COG4603	Belongs to the binding-protein-dependent transport system permease family
BTB_RS18970	COG3845	ABC transporter
BTB_RS18975	COG1744	ABC transporter substrate-binding protein PnrA-like
BTB_RS18980	COG2188	Transcriptional regulator
BTB_RS19000	COG0740	serine-type endopeptidase activity
BTB_RS19005	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTB_RS19015	COG0527	aspartate kinase activity
BTB_RS19020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTB_RS19025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTB_RS19035	COG5444	nuclease activity
BTB_RS19060	COG3547	Transposase (IS116 IS110 IS902 family)
BTB_RS19170	COG0582	viral genome integration into host DNA
BTB_RS19215	COG0305	Participates in initiation and elongation during chromosome replication
BTB_RS19250	COG1396	sequence-specific DNA binding
BTB_RS19275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTB_RS19280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTB_RS19285	COG1873	PFAM PRC-barrel domain
BTB_RS19290	COG0612	Peptidase, M16
BTB_RS19295	COG0726	polysaccharide deacetylase
BTB_RS19310	COG0196	riboflavin kinase activity
BTB_RS19320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BTB_RS19325	COG1550	Protein conserved in bacteria
BTB_RS19335	COG1358	cellular component organization or biogenesis
BTB_RS19340	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BTB_RS19345	COG0195	Participates in both transcription termination and antitermination
BTB_RS19365	COG0750	zinc metalloprotease
BTB_RS19375	COG4589	Belongs to the CDS family
BTB_RS19420	COG4974	Belongs to the 'phage' integrase family
BTB_RS19430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTB_RS19435	COG0758	DNA mediated transformation
BTB_RS19440	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BTB_RS19480	COG1837	Belongs to the UPF0109 family
BTB_RS19490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTB_RS19500	COG0552	protein localization to endoplasmic reticulum
BTB_RS19505	COG1196	nuclear chromosome segregation
BTB_RS19515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTB_RS19520	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS19525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BTB_RS19540	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BTB_RS19545	COG1461	Dihydroxyacetone kinase
BTB_RS19550	COG1302	Protein conserved in bacteria
BTB_RS19565	COG1564	THIamine pyrophosphokinase
BTB_RS19570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BTB_RS19580	COG0515	serine threonine protein kinase
BTB_RS19580	COG2815	serine threonine protein kinase
BTB_RS19585	COG0631	protein serine/threonine phosphatase activity
BTB_RS19595	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTB_RS19595	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTB_RS19610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BTB_RS19615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTB_RS19635	COG1561	YicC-like family, N-terminal region
BTB_RS19640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BTB_RS19655	COG0006	proline dipeptidase activity
BTB_RS19675	COG3069	C4-dicarboxylate transmembrane transporter activity
BTB_RS19740	COG0564	pseudouridine synthase activity
BTB_RS19760	COG3599	regulation of cell shape
BTB_RS19765	COG2302	S4 RNA-binding domain
BTB_RS19770	COG0762	integral membrane protein
BTB_RS19780	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BTB_RS19790	COG1873	PFAM PRC-barrel domain
BTB_RS19795	COG1191	sigma factor activity
BTB_RS19800	COG1191	sigma factor activity
BTB_RS19810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BTB_RS19815	COG0849	cell division
BTB_RS19835	COG0772	Belongs to the SEDS family
BTB_RS19855	COG0768	penicillin binding
BTB_RS19860	COG0768	penicillin binding
BTB_RS19880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTB_RS19895	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BTB_RS19900	COG1399	metal-binding, possibly nucleic acid-binding protein
BTB_RS19910	COG3480	Lon protease (S16) C-terminal proteolytic domain
BTB_RS19915	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTB_RS19920	COG3314	Sporulation integral membrane protein YlbJ
BTB_RS19930	COG0742	ribosomal rna small subunit methyltransferase
BTB_RS19945	COG3679	Belongs to the UPF0342 family
BTB_RS19950	COG0406	alpha-ribazole phosphatase activity
BTB_RS19965	COG2340	Cysteine-rich secretory protein family
BTB_RS19980	COG2801	Transposase and inactivated derivatives
BTB_RS19990	COG3344	reverse transcriptase
BTB_RS20000	COG3336	cytochrome c oxidase
BTB_RS20035	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BTB_RS20040	COG0772	Belongs to the SEDS family
BTB_RS20050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BTB_RS20055	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BTB_RS20065	COG4896	Protein conserved in bacteria
BTB_RS20080	COG1217	gtp-binding protein TYPA
BTB_RS20090	COG0483	inositol monophosphate 1-phosphatase activity
BTB_RS20110	COG1982	Orn Lys Arg decarboxylase major
BTB_RS20160	COG0022	dehydrogenase e1 component
BTB_RS20165	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTB_RS20180	COG0561	phosphatase activity
BTB_RS20190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTB_RS20195	COG0569	domain protein
BTB_RS20215	COG0583	DNA-binding transcription factor activity
BTB_RS20220	COG0517	IMP dehydrogenase activity
BTB_RS20230	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BTB_RS20240	COG4703	Protein of unknown function (DUF1797)
BTB_RS20255	COG2200	EAL domain
BTB_RS20260	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS20265	COG1408	metallophosphoesterase
BTB_RS20310	COG2814	Major facilitator Superfamily
BTB_RS20330	COG3209	COG3209 Rhs family protein
BTB_RS20340	COG2205	protein histidine kinase activity
BTB_RS20350	COG0436	Aminotransferase
BTB_RS20355	COG1609	Transcriptional regulator
BTB_RS20360	COG3833	ABC-type maltose transport systems, permease component
BTB_RS20365	COG1175	transmembrane transport
BTB_RS20370	COG2182	Extracellular solute-binding protein
BTB_RS20380	COG0366	Alpha amylase catalytic
BTB_RS20385	COG3842	ATPase activity
BTB_RS20425	COG0183	Belongs to the thiolase family
BTB_RS20455	COG1695	Transcriptional regulator
BTB_RS20460	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS20480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTB_RS20485	COG0436	Aminotransferase
BTB_RS20520	COG2084	Dehydrogenase
BTB_RS20530	COG2199	diguanylate cyclase activity
BTB_RS20535	COG0778	Nitroreductase
BTB_RS20560	COG1263	PTS System
BTB_RS20560	COG2190	(PTS) system
BTB_RS20560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTB_RS20565	COG3711	transcriptional antiterminator
BTB_RS20575	COG2188	Transcriptional regulator
BTB_RS20585	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BTB_RS20605	COG1547	Domain of unknown function (DUF309)
BTB_RS20610	COG0456	acetyltransferase
BTB_RS20615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTB_RS20620	COG4086	secreted protein
BTB_RS20625	COG0561	phosphatase activity
BTB_RS20630	COG0697	spore germination
BTB_RS20645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTB_RS20670	COG0733	neurotransmitter:sodium symporter activity
BTB_RS20690	COG1686	Belongs to the peptidase S11 family
BTB_RS20695	COG1725	Transcriptional regulator
BTB_RS20700	COG1131	(ABC) transporter
BTB_RS20720	COG1846	Transcriptional regulator
BTB_RS20735	COG0598	Magnesium transport protein CorA
BTB_RS20760	COG4974	Belongs to the 'phage' integrase family
BTB_RS20770	COG0735	belongs to the Fur family
BTB_RS20775	COG1300	Membrane
BTB_RS20795	COG0667	Aldo Keto reductase
BTB_RS20800	COG0656	L-ascorbic acid biosynthetic process
BTB_RS20805	COG0456	acetyltransferase
BTB_RS20805	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTB_RS20815	COG0737	Belongs to the 5'-nucleotidase family
BTB_RS20815	COG4085	toxin activity
BTB_RS20815	COG1525	nuclease
BTB_RS20825	COG0596	Alpha beta hydrolase
BTB_RS20830	COG2056	Na+-H+ antiporter family
BTB_RS20835	COG1609	Transcriptional regulator
BTB_RS20840	COG0456	acetyltransferase
BTB_RS20845	COG1073	alpha beta
BTB_RS20860	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTB_RS20860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTB_RS20865	COG0307	riboflavin synthase, alpha
BTB_RS20895	COG2226	methyltransferase
BTB_RS20895	COG1073	alpha beta
BTB_RS20910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTB_RS20920	COG1757	Na H antiporter
BTB_RS20925	COG0737	Belongs to the 5'-nucleotidase family
BTB_RS20935	COG1522	sequence-specific DNA binding
BTB_RS20975	COG5444	nuclease activity
BTB_RS21010	COG0300	oxidoreductase activity
BTB_RS21015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTB_RS21020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTB_RS21025	COG1760	l-serine dehydratase
BTB_RS21030	COG1760	l-serine dehydratase
BTB_RS21060	COG1285	pathogenesis
BTB_RS21070	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTB_RS21075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTB_RS21085	COG1376	ErfK ybiS ycfS ynhG family protein
BTB_RS21090	COG4129	membrane
BTB_RS21095	COG1126	abc transporter atp-binding protein
BTB_RS21100	COG0765	amino acid transport
BTB_RS21105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTB_RS21125	COG2323	membrane
BTB_RS21130	COG0772	Belongs to the SEDS family
BTB_RS21135	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTB_RS21140	COG0022	dehydrogenase e1 component
BTB_RS21145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTB_RS21150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTB_RS21165	COG0280	phosphate acetyltransferase
BTB_RS21175	COG3290	protein histidine kinase activity
BTB_RS21175	COG3829	transcription factor binding
BTB_RS21185	COG0584	glycerophosphoryl diester phosphodiesterase
BTB_RS21190	COG3093	addiction module antidote protein HigA
BTB_RS21205	COG0750	zinc metalloprotease
BTB_RS21210	COG0497	DNA recombination
BTB_RS21220	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BTB_RS21230	COG0142	geranyltranstransferase activity
BTB_RS21255	COG1302	Protein conserved in bacteria
BTB_RS21260	COG0439	Biotin carboxylase
BTB_RS21265	COG0511	ligase activity, forming carbon-carbon bonds
BTB_RS21305	COG3854	ATPases associated with a variety of cellular activities
BTB_RS21330	COG0006	proline dipeptidase activity
BTB_RS21345	COG3872	metal-dependent enzyme
BTB_RS21355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTB_RS21390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTB_RS21400	COG1609	Transcriptional regulator
BTB_RS21410	COG2076	Multidrug Resistance protein
BTB_RS21415	COG2076	Multidrug Resistance protein
BTB_RS21450	COG1725	Transcriptional regulator
BTB_RS21480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTB_RS21545	COG1459	type II secretion system
BTB_RS21550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BTB_RS21615	COG1410	methionine synthase
BTB_RS21615	COG0646	methionine synthase
BTB_RS21620	COG0646	methionine synthase
BTB_RS21620	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BTB_RS21625	COG0626	cystathionine gamma-synthase activity
BTB_RS21630	COG0626	cystathionine gamma-synthase activity
BTB_RS21650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTB_RS21660	COG1940	carbohydrate kinase activity
BTB_RS21665	COG4483	Protein conserved in bacteria
BTB_RS21670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTB_RS21675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BTB_RS21680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTB_RS21685	COG0704	Plays a role in the regulation of phosphate uptake
BTB_RS21695	COG0573	inorganic phosphate transmembrane transporter activity
BTB_RS21700	COG0573	inorganic phosphate transmembrane transporter activity
BTB_RS21705	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BTB_RS21710	COG0768	penicillin binding
BTB_RS21715	COG0477	Major facilitator Superfamily
BTB_RS21720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTB_RS21730	COG5521	maltodextrose utilization protein MalA
BTB_RS21745	COG0735	belongs to the Fur family
BTB_RS21750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTB_RS21755	COG1121	(ABC) transporter
BTB_RS21760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTB_RS21790	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BTB_RS21795	COG2384	SAM-dependent methyltransferase
BTB_RS21805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTB_RS21810	COG0358	DNA primase activity
BTB_RS21820	COG0517	IMP dehydrogenase activity
BTB_RS21835	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BTB_RS21840	COG0295	cytidine deaminase activity
BTB_RS21845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BTB_RS21855	COG1480	7TM receptor with intracellular HD hydrolase
BTB_RS21860	COG1702	phosphate starvation-inducible protein PhoH
BTB_RS21880	COG1610	YqeY-like protein
BTB_RS21885	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BTB_RS21890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTB_RS21895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BTB_RS21925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTB_RS21930	COG1733	regulation of RNA biosynthetic process
BTB_RS21955	COG1466	dna polymerase III delta subunit
BTB_RS21965	COG0658	competence protein
BTB_RS21965	COG2333	competence protein COMEC
BTB_RS21970	COG2131	deaminase
BTB_RS21975	COG1555	photosystem II stabilization
BTB_RS21975	COG1596	polysaccharide export
BTB_RS21980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTB_RS21985	COG2226	methyltransferase
BTB_RS21990	COG0799	negative regulation of ribosome biogenesis
BTB_RS21995	COG1713	HD superfamily hydrolase involved in NAD metabolism
BTB_RS22005	COG1534	Rna-binding protein
BTB_RS22015	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BTB_RS22020	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BTB_RS22045	COG1595	DNA-templated transcription, initiation
BTB_RS22055	COG0778	Nitroreductase
BTB_RS22060	COG2357	RelA SpoT domain protein
BTB_RS22070	COG1785	Belongs to the alkaline phosphatase family
BTB_RS22080	COG2267	carboxylic ester hydrolase activity
BTB_RS22115	COG1404	Belongs to the peptidase S8 family
BTB_RS22120	COG3186	Phenylalanine-4-hydroxylase
BTB_RS22130	COG2514	catechol 2,3-dioxygenase activity
BTB_RS22135	COG2259	Doxx family
BTB_RS22175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTB_RS22185	COG1454	alcohol dehydrogenase
BTB_RS22185	COG1012	belongs to the aldehyde dehydrogenase family
BTB_RS22190	COG0626	cystathionine gamma-synthase activity
BTB_RS22195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTB_RS22220	COG0768	penicillin binding
BTB_RS22235	COG0826	peptidase U32
BTB_RS22240	COG0826	peptidase U32
BTB_RS22245	COG4122	O-methyltransferase activity
BTB_RS22250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BTB_RS22265	COG4472	Bacterial protein of unknown function (DUF965)
BTB_RS22280	COG0628	permease
BTB_RS22300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BTB_RS22315	COG1104	cysteine desulfurase activity
BTB_RS22320	COG1959	2 iron, 2 sulfur cluster binding
BTB_RS22325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BTB_RS22335	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BTB_RS22360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTB_RS22370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BTB_RS22370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BTB_RS22375	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTB_RS22380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTB_RS22380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTB_RS22390	COG2244	polysaccharide biosynthetic process
BTB_RS22395	COG2323	membrane
BTB_RS22405	COG1862	Preprotein translocase
BTB_RS22435	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BTB_RS22465	COG0157	Belongs to the NadC ModD family
BTB_RS22470	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BTB_RS22475	COG1104	cysteine desulfurase activity
BTB_RS22480	COG1827	regulation of RNA biosynthetic process
BTB_RS22485	COG2258	MOSC domain
BTB_RS22490	COG0077	Prephenate dehydratase
BTB_RS22495	COG0577	efflux transmembrane transporter activity
BTB_RS22500	COG0577	efflux transmembrane transporter activity
BTB_RS22505	COG1136	(ABC) transporter
BTB_RS22510	COG5002	protein histidine kinase activity
BTB_RS22515	COG0745	RESPONSE REGULATOR receiver
BTB_RS22525	COG3290	protein histidine kinase activity
BTB_RS22535	COG2868	ribosomal protein
BTB_RS22545	COG1530	ribonuclease E activity
BTB_RS22550	COG1994	Peptidase M50
BTB_RS22555	COG0739	heme binding
BTB_RS22560	COG2894	cell division
BTB_RS22580	COG1077	Cell shape determining protein MreB Mrl
BTB_RS22600	COG0285	dihydrofolate synthase activity
BTB_RS22615	COG1388	LysM domain
BTB_RS22625	COG0113	porphobilinogen synthase activity
BTB_RS22630	COG1587	Uroporphyrinogen-III synthase
BTB_RS22640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTB_RS22650	COG1846	Transcriptional regulator
BTB_RS22655	COG1764	response to oxidative stress
BTB_RS22670	COG0470	DNA polymerase III
BTB_RS22670	COG1067	ATP-dependent peptidase activity
BTB_RS22765	COG3611	Membrane attachment protein
BTB_RS22805	COG0622	Phosphoesterase
BTB_RS22820	COG5401	PFAM Sporulation and spore germination
BTB_RS22840	COG1309	transcriptional regulator
BTB_RS22850	COG2197	response regulator
BTB_RS22855	COG2233	PERMEase
BTB_RS22860	COG0402	S-adenosylhomocysteine deaminase activity
BTB_RS22865	COG1983	PspC domain protein
BTB_RS22870	COG1396	sequence-specific DNA binding
BTB_RS22875	COG0697	spore germination
BTB_RS22885	COG1959	2 iron, 2 sulfur cluster binding
BTB_RS22890	COG1668	transmembrane transport
BTB_RS22895	COG4152	abc transporter atp-binding protein
BTB_RS22900	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BTB_RS22905	COG1360	Flagellar Motor Protein
BTB_RS22910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BTB_RS22915	COG1876	peptidase activity
BTB_RS22920	COG0824	Thioesterase
BTB_RS22925	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BTB_RS22930	COG1053	succinate dehydrogenase
BTB_RS22935	COG2009	succinate dehydrogenase
BTB_RS22940	COG1719	4-vinyl reductase, 4VR
BTB_RS22950	COG3118	belongs to the thioredoxin family
BTB_RS22955	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BTB_RS22960	COG2086	electron transfer activity
BTB_RS22965	COG1024	Enoyl-CoA hydratase
BTB_RS22970	COG1309	transcriptional regulator
BTB_RS22975	COG0318	PFAM AMP-dependent synthetase and ligase
BTB_RS23000	COG2318	DinB family
BTB_RS23025	COG1131	(ABC) transporter
BTB_RS23030	COG2205	protein histidine kinase activity
BTB_RS23035	COG0745	RESPONSE REGULATOR receiver
BTB_RS23045	COG4895	conserved protein (DUF2196)
BTB_RS23050	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BTB_RS23060	COG4509	Sortase family
BTB_RS23065	COG1120	ATPase activity
BTB_RS23090	COG5386	Cell surface protein
BTB_RS23095	COG1114	Component of the transport system for branched-chain amino acids
BTB_RS23100	COG1187	pseudouridine synthase activity
BTB_RS23110	COG1796	DNA polymerase
BTB_RS23110	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTB_RS23115	COG1286	toxin biosynthetic process
BTB_RS23150	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BTB_RS23155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTB_RS23165	COG1418	mRNA catabolic process
BTB_RS23185	COG2814	Major facilitator Superfamily
BTB_RS23190	COG1566	PFAM secretion protein HlyD family protein
BTB_RS23195	COG1309	transcriptional regulator
BTB_RS23200	COG1363	Peptidase, m42
BTB_RS23225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTB_RS23240	COG1484	DNA-dependent DNA replication
BTB_RS23245	COG3611	Membrane attachment protein
BTB_RS23255	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BTB_RS23260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTB_RS23265	COG0237	dephospho-CoA kinase activity
BTB_RS23270	COG1971	Probably functions as a manganese efflux pump
BTB_RS23280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTB_RS23280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTB_RS23285	COG5002	protein histidine kinase activity
BTB_RS23290	COG0745	RESPONSE REGULATOR receiver
BTB_RS23310	COG0538	isocitrate dehydrogenase activity
BTB_RS23315	COG0372	Belongs to the citrate synthase family
BTB_RS23325	COG0628	permease
BTB_RS23330	COG3030	protein affecting phage T7 exclusion by the F plasmid
BTB_RS23355	COG1725	Transcriptional regulator
BTB_RS23360	COG0281	malic enzyme
BTB_RS23365	COG0587	DNA-directed DNA polymerase activity
BTB_RS23380	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BTB_RS23395	COG4109	DRTGG domain
BTB_RS23410	COG0006	proline dipeptidase activity
BTB_RS23445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTB_RS23450	COG0662	Cupin 2, conserved barrel domain protein
BTB_RS23465	COG1028	Short-chain dehydrogenase reductase Sdr
BTB_RS23470	COG0589	response to stress
BTB_RS23510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTB_RS23535	COG0827	DNA restriction-modification system
BTB_RS23540	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BTB_RS23545	COG3874	Sporulation protein YtfJ
BTB_RS23560	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BTB_RS23570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTB_RS23585	COG1104	cysteine desulfurase activity
BTB_RS23595	COG0583	DNA-binding transcription factor activity
BTB_RS23600	COG0697	spore germination
BTB_RS23605	COG1309	transcriptional regulator
BTB_RS23610	COG1956	GAF domain-containing protein
BTB_RS23615	COG0626	cystathionine gamma-synthase activity
BTB_RS23645	COG1595	DNA-templated transcription, initiation
BTB_RS23655	COG0110	maltose O-acetyltransferase activity
BTB_RS23660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTB_RS23665	COG0454	-acetyltransferase
BTB_RS23670	COG0517	IMP dehydrogenase activity
BTB_RS23675	COG0123	including yeast histone deacetylase and acetoin utilization protein
BTB_RS23680	COG2267	carboxylic ester hydrolase activity
BTB_RS23690	COG0745	RESPONSE REGULATOR receiver
BTB_RS23695	COG5002	protein histidine kinase activity
BTB_RS23700	COG0666	response to abiotic stimulus
BTB_RS23730	COG1609	Transcriptional regulator
BTB_RS23735	COG1605	Chorismate mutase
BTB_RS23735	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTB_RS23740	COG1605	Chorismate mutase
BTB_RS23740	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTB_RS23745	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTB_RS23745	COG1605	Chorismate mutase
BTB_RS23750	COG4851	CamS sex pheromone cAM373 precursor
BTB_RS23755	COG3118	belongs to the thioredoxin family
BTB_RS23765	COG2309	aminopeptidase activity
BTB_RS23780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTB_RS23785	COG0697	spore germination
BTB_RS23790	COG0789	Transcriptional regulator
BTB_RS23805	COG1674	ftsk spoiiie
BTB_RS23820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTB_RS23830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTB_RS23835	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BTB_RS23840	COG1363	Peptidase, m42
BTB_RS23850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTB_RS23865	COG0510	thiamine kinase activity
BTB_RS23870	COG1523	belongs to the glycosyl hydrolase 13 family
BTB_RS23880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTB_RS23885	COG1349	DNA-binding transcription factor activity
BTB_RS23890	COG1187	pseudouridine synthase activity
BTB_RS23895	COG2244	polysaccharide biosynthetic process
BTB_RS23900	COG2081	HI0933 family
BTB_RS23905	COG2814	Major facilitator Superfamily
BTB_RS23915	COG3832	glyoxalase III activity
BTB_RS23935	COG1329	Transcriptional regulator
BTB_RS23960	COG0314	molybdopterin synthase activity
BTB_RS23965	COG1763	Mo-molybdopterin cofactor biosynthetic process
BTB_RS23970	COG0303	'Molybdopterin
BTB_RS23980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTB_RS23985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTB_RS24005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTB_RS24015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTB_RS24055	COG2814	Major facilitator Superfamily
BTB_RS24060	COG0475	glutathione-regulated potassium exporter activity
BTB_RS24065	COG0490	domain, Protein
BTB_RS24070	COG0582	viral genome integration into host DNA
BTB_RS24080	COG1136	(ABC) transporter
BTB_RS24110	COG1242	4 iron, 4 sulfur cluster binding
BTB_RS24115	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BTB_RS24120	COG1131	(ABC) transporter
BTB_RS24130	COG1794	racemase activity, acting on amino acids and derivatives
BTB_RS24150	COG2267	carboxylic ester hydrolase activity
BTB_RS24155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTB_RS24160	COG0671	phosphoesterase, PA-phosphatase related
BTB_RS24165	COG0438	transferase activity, transferring glycosyl groups
BTB_RS24245	COG5002	protein histidine kinase activity
BTB_RS24250	COG3852	Histidine kinase
BTB_RS24255	COG0753	catalase activity
BTB_RS24260	COG2267	carboxylic ester hydrolase activity
BTB_RS24265	COG1368	sulfuric ester hydrolase activity
BTB_RS24285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTB_RS24290	COG1116	anion transmembrane transporter activity
BTB_RS24295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTB_RS24320	COG0494	nUDIX hydrolase
BTB_RS24350	COG2076	Multidrug Resistance protein
BTB_RS24355	COG2076	Multidrug Resistance protein
BTB_RS24360	COG0789	Transcriptional regulator
BTB_RS24365	COG1854	S-ribosylhomocysteine lyase activity
BTB_RS24375	COG0288	reversible hydration of carbon dioxide
BTB_RS24380	COG1271	oxidase subunit
BTB_RS24385	COG1294	oxidase, subunit
BTB_RS24400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTB_RS24420	COG1842	Phage shock protein A
BTB_RS24445	COG3859	Proton-coupled thiamine transporter YuaJ
BTB_RS24450	COG5002	protein histidine kinase activity
BTB_RS24455	COG0745	RESPONSE REGULATOR receiver
BTB_RS24480	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTB_RS24485	COG1597	lipid kinase activity
BTB_RS24495	COG0577	efflux transmembrane transporter activity
BTB_RS24500	COG1136	(ABC) transporter
BTB_RS24515	COG0586	Pfam SNARE associated Golgi protein
BTB_RS24525	COG0577	efflux transmembrane transporter activity
BTB_RS24530	COG1136	(ABC) transporter
BTB_RS24535	COG3708	Transcriptional regulator
BTB_RS24535	COG2207	Transcriptional regulator
BTB_RS24545	COG5658	integral membrane protein
BTB_RS24550	COG0640	Transcriptional regulator
BTB_RS24555	COG0745	RESPONSE REGULATOR receiver
BTB_RS24560	COG2205	protein histidine kinase activity
BTB_RS24565	COG0577	efflux transmembrane transporter activity
BTB_RS24570	COG0577	efflux transmembrane transporter activity
BTB_RS24575	COG1136	(ABC) transporter
BTB_RS24580	COG0577	efflux transmembrane transporter activity
BTB_RS24605	COG2188	Transcriptional regulator
BTB_RS24625	COG3964	amidohydrolase
BTB_RS24645	COG4948	Mandelate Racemase Muconate Lactonizing
BTB_RS24655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BTB_RS24660	COG0596	Alpha beta hydrolase
BTB_RS24670	COG1169	isochorismate synthase
BTB_RS24675	COG1575	Belongs to the MenA family. Type 1 subfamily
BTB_RS24680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BTB_RS24685	COG1278	Cold shock
BTB_RS24710	COG0058	SHG alpha-glucan phosphorylase activity
BTB_RS24720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BTB_RS24740	COG1404	Belongs to the peptidase S8 family
BTB_RS24875	COG1285	pathogenesis
BTB_RS24880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTB_RS24895	COG2155	Conserved Protein
BTB_RS24900	COG1098	S1 RNA binding domain
BTB_RS24905	COG0436	Aminotransferase
BTB_RS24910	COG1522	sequence-specific DNA binding
BTB_RS24915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTB_RS24920	COG2267	carboxylic ester hydrolase activity
BTB_RS24930	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BTB_RS24950	COG5018	Exonuclease
BTB_RS24955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTB_RS24975	COG2050	protein possibly involved in aromatic compounds catabolism
BTB_RS24985	COG1268	BioY protein
BTB_RS24990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTB_RS24995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTB_RS25015	COG2076	Multidrug Resistance protein
BTB_RS25020	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BTB_RS25030	COG3584	3D domain protein
BTB_RS25045	COG1252	NADH dehydrogenase
BTB_RS25060	COG3708	Transcriptional regulator
BTB_RS25075	COG1683	Conserved Protein
BTB_RS25125	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTB_RS25125	COG3409	Peptidoglycan-binding domain 1 protein
BTB_RS25125	COG1388	LysM domain
BTB_RS25130	COG4824	toxin secretion phage lysis holin
BTB_RS25265	COG1191	sigma factor activity
BTB_RS25290	COG3645	SOS response
BTB_RS25290	COG3646	Phage regulatory protein
BTB_RS25310	COG1396	sequence-specific DNA binding
BTB_RS25345	COG4122	O-methyltransferase activity
BTB_RS25360	COG0316	Belongs to the HesB IscA family
BTB_RS25375	COG1252	NADH dehydrogenase
BTB_RS25385	COG0390	transport system, permease component
BTB_RS25390	COG2824	Alkylphosphonate utilization operon protein PhnA
BTB_RS25415	COG4837	Protein of unknown function (DUF1462)
BTB_RS25420	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BTB_RS25430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTB_RS25435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BTB_RS25455	COG1358	cellular component organization or biogenesis
BTB_RS25465	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTB_RS25470	COG0647	UMP catabolic process
BTB_RS25480	COG2445	Protein of unknown function DUF86
BTB_RS25485	COG1494	fructose-1,6-bisphosphatase
BTB_RS25505	COG4470	Protein conserved in bacteria
BTB_RS25515	COG0789	Transcriptional regulator
BTB_RS25520	COG4377	Putative membrane peptidase family (DUF2324)
BTB_RS25545	COG0739	heme binding
BTB_RS25555	COG3377	Domain of unknown function (DUF1805)
BTB_RS25560	COG0737	Belongs to the 5'-nucleotidase family
BTB_RS25565	COG0719	Fe-S assembly protein
BTB_RS25570	COG0822	iron-sulfur transferase activity
BTB_RS25575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BTB_RS25580	COG0719	Fe-S assembly protein
BTB_RS25585	COG0396	ATPase activity
BTB_RS25590	COG1464	Belongs to the NlpA lipoprotein family
BTB_RS25595	COG1464	Belongs to the NlpA lipoprotein family
BTB_RS25600	COG2011	ABC-type metal ion transport system permease component
BTB_RS25615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTB_RS25620	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BTB_RS25630	COG1393	Belongs to the ArsC family
BTB_RS25665	COG0039	L-malate dehydrogenase activity
BTB_RS25685	COG1309	transcriptional regulator
BTB_RS25690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTB_RS25695	COG1960	acyl-CoA dehydrogenase activity
BTB_RS25700	COG0183	Belongs to the thiolase family
BTB_RS25705	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTB_RS25705	COG1024	Enoyl-CoA hydratase
BTB_RS25715	COG1686	Belongs to the peptidase S11 family
BTB_RS25730	COG0011	TIGRFAM Protein of
BTB_RS25735	COG0840	transmembrane signaling receptor activity
BTB_RS25750	COG2814	Major facilitator Superfamily
BTB_RS25755	COG0531	amino acid
BTB_RS25780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTB_RS25810	COG0586	Pfam SNARE associated Golgi protein
BTB_RS25820	COG1376	ErfK ybiS ycfS ynhG family protein
BTB_RS25825	COG0745	RESPONSE REGULATOR receiver
BTB_RS25830	COG5002	protein histidine kinase activity
BTB_RS25860	COG0840	transmembrane signaling receptor activity
BTB_RS25865	COG2151	metal-sulfur cluster biosynthetic enzyme
BTB_RS25870	COG3227	Zinc metalloprotease (Elastase)
BTB_RS25890	COG0586	Pfam SNARE associated Golgi protein
BTB_RS25895	COG0475	glutathione-regulated potassium exporter activity
BTB_RS25900	COG0490	domain, Protein
BTB_RS25905	COG1115	amino acid carrier protein
BTB_RS25910	COG0783	Belongs to the Dps family
BTB_RS25920	COG2318	DinB family
BTB_RS25930	COG1611	Belongs to the LOG family
BTB_RS25940	COG1528	Iron-storage protein
BTB_RS25950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTB_RS25955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTB_RS25960	COG1115	amino acid carrier protein
BTB_RS25965	COG1115	amino acid carrier protein
BTB_RS25970	COG2910	NAD(P)H-binding
BTB_RS25985	COG0656	L-ascorbic acid biosynthetic process
BTB_RS25990	COG2814	Major facilitator Superfamily
BTB_RS25995	COG1733	regulation of RNA biosynthetic process
BTB_RS26005	COG1252	NADH dehydrogenase
BTB_RS26010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BTB_RS26060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTB_RS26075	COG1335	isochorismatase
BTB_RS26080	COG1522	sequence-specific DNA binding
BTB_RS26145	COG0557	exoribonuclease II activity
BTB_RS26150	COG1647	Serine aminopeptidase, S33
BTB_RS26155	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTB_RS26160	COG1346	cytolysis
BTB_RS26195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTB_RS26210	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BTB_RS26220	COG4585	Histidine kinase
BTB_RS26250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTB_RS26265	COG2323	membrane
BTB_RS26275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTB_RS26285	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BTB_RS26295	COG1051	belongs to the nudix hydrolase family
BTB_RS26305	COG0492	ferredoxin-NADP+ reductase activity
BTB_RS26310	COG0457	Tetratricopeptide repeat
BTB_RS26315	COG0110	maltose O-acetyltransferase activity
BTB_RS26335	COG1950	PFAM Membrane protein of
BTB_RS26345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BTB_RS26365	COG0789	Transcriptional regulator
BTB_RS26385	COG0583	DNA-binding transcription factor activity
BTB_RS26395	COG0655	NAD(P)H dehydrogenase (quinone) activity
BTB_RS26400	COG0488	(ABC) transporter
BTB_RS26410	COG1132	(ABC) transporter
BTB_RS26415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTB_RS26420	COG3409	Peptidoglycan-binding domain 1 protein
BTB_RS26420	COG0793	Belongs to the peptidase S41A family
BTB_RS26425	COG2177	Part of the ABC transporter FtsEX involved in
BTB_RS26430	COG2884	Cell division ATP-binding protein ftsE
BTB_RS26440	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BTB_RS26450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BTB_RS26455	COG1278	Cold shock
BTB_RS26460	COG1040	competence protein
BTB_RS26465	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BTB_RS26470	COG0791	NLP P60 protein
BTB_RS26470	COG1388	LysM domain
BTB_RS26475	COG1733	regulation of RNA biosynthetic process
BTB_RS26480	COG1307	EDD domain protein, DegV family
BTB_RS26490	COG1316	TRANSCRIPTIONal
BTB_RS26495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BTB_RS26500	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BTB_RS26505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTB_RS26515	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BTB_RS26515	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BTB_RS26535	COG1486	melibiose metabolic process
BTB_RS26540	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTB_RS26545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTB_RS26565	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTB_RS26575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTB_RS26580	COG1301	dicarboxylic acid transport
BTB_RS26595	COG1511	domain protein
BTB_RS26600	COG0583	DNA-binding transcription factor activity
BTB_RS26605	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BTB_RS26615	COG1271	oxidase subunit
BTB_RS26620	COG1294	oxidase, subunit
BTB_RS26625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTB_RS26650	COG1620	l-lactate permease
BTB_RS26660	COG2389	metal-binding protein
BTB_RS26670	COG1368	sulfuric ester hydrolase activity
BTB_RS26680	COG0791	NLP P60 protein
BTB_RS26680	COG1388	LysM domain
BTB_RS26685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTB_RS26695	COG1215	transferase activity, transferring glycosyl groups
BTB_RS26705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTB_RS26710	COG1388	LysM domain
BTB_RS26710	COG3584	3D domain protein
BTB_RS26735	COG4715	Zinc finger, swim domain protein
BTB_RS26740	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTB_RS26750	COG3547	Transposase (IS116 IS110 IS902 family)
BTB_RS26785	COG0577	efflux transmembrane transporter activity
BTB_RS26790	COG1136	(ABC) transporter
BTB_RS26825	COG5002	protein histidine kinase activity
BTB_RS26830	COG0745	RESPONSE REGULATOR receiver
BTB_RS26835	COG1482	cell wall glycoprotein biosynthetic process
BTB_RS26840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTB_RS26840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTB_RS26840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTB_RS26845	COG3711	transcriptional antiterminator
BTB_RS26845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTB_RS26850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTB_RS26865	COG1482	cell wall glycoprotein biosynthetic process
BTB_RS26870	COG0662	Cupin 2, conserved barrel domain protein
BTB_RS26870	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BTB_RS26885	COG0438	transferase activity, transferring glycosyl groups
BTB_RS26895	COG0297	glycogen (starch) synthase activity
BTB_RS26895	COG0438	transferase activity, transferring glycosyl groups
BTB_RS26900	COG0110	maltose O-acetyltransferase activity
BTB_RS26920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTB_RS26925	COG4464	protein tyrosine phosphatase activity
BTB_RS26930	COG0489	protein tyrosine kinase activity
BTB_RS26935	COG3944	biosynthesis protein
BTB_RS26940	COG0489	protein tyrosine kinase activity
BTB_RS26955	COG1609	Transcriptional regulator
BTB_RS26965	COG0739	heme binding
BTB_RS26980	COG3279	Response regulator of the LytR AlgR family
BTB_RS26985	COG2385	sporulation resulting in formation of a cellular spore
BTB_RS27000	COG4836	Membrane
BTB_RS27005	COG1007	ATP synthesis coupled electron transport
BTB_RS27010	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTB_RS27015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTB_RS27025	COG0839	Belongs to the complex I subunit 6 family
BTB_RS27045	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTB_RS27060	COG3300	MHYT domain
BTB_RS27060	COG5001	Diguanylate cyclase
BTB_RS27110	COG0356	it plays a direct role in the translocation of protons across the membrane
BTB_RS27145	COG0698	ribose 5-phosphate isomerase
BTB_RS27155	COG2190	(PTS) system
BTB_RS27160	COG2259	Doxx family
BTB_RS27165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTB_RS27180	COG0009	L-threonylcarbamoyladenylate synthase
BTB_RS27215	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BTB_RS27220	COG1494	fructose-1,6-bisphosphatase
BTB_RS27240	COG4821	SIS domain
BTB_RS27260	COG1960	acyl-CoA dehydrogenase activity
BTB_RS27265	COG1960	acyl-CoA dehydrogenase activity
BTB_RS27270	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTB_RS27275	COG0183	Belongs to the thiolase family
BTB_RS27280	COG2181	nitrate reductase activity
BTB_RS27280	COG0247	lactate metabolic process
BTB_RS27285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTB_RS27295	COG5001	Diguanylate cyclase
BTB_RS27295	COG3300	MHYT domain
BTB_RS27310	COG3227	Zinc metalloprotease (Elastase)
BTB_RS27315	COG2197	response regulator
BTB_RS27320	COG4585	Histidine kinase
BTB_RS27325	COG0842	Transport permease protein
BTB_RS27330	COG1131	(ABC) transporter
BTB_RS27335	COG0024	Methionine aminopeptidase
BTB_RS27345	COG2234	aminopeptidase activity
BTB_RS27365	COG1595	DNA-templated transcription, initiation
BTB_RS27375	COG4506	Protein conserved in bacteria
BTB_RS27380	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTB_RS27410	COG2814	Major facilitator Superfamily
BTB_RS27415	COG0789	Transcriptional regulator
BTB_RS27420	COG0584	glycerophosphoryl diester phosphodiesterase
BTB_RS27425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTB_RS27435	COG1994	Peptidase M50
BTB_RS27445	COG1078	dGTPase activity
BTB_RS27450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTB_RS27455	COG1120	ATPase activity
BTB_RS27460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTB_RS27465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTB_RS27485	COG0280	phosphate acetyltransferase
BTB_RS27500	COG3773	Cell wall hydrolase
BTB_RS27510	COG2363	Small membrane protein
BTB_RS27520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTB_RS27525	COG2233	PERMEase
BTB_RS27530	COG0561	phosphatase activity
BTB_RS27535	COG2814	Major facilitator Superfamily
BTB_RS27545	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BTB_RS27550	COG1131	(ABC) transporter
BTB_RS27555	COG2755	lipolytic protein G-D-S-L family
BTB_RS27560	COG1609	Transcriptional regulator
BTB_RS27570	COG0460	homoserine dehydrogenase
BTB_RS27580	COG2873	o-acetylhomoserine
BTB_RS27590	COG1011	Hydrolase
BTB_RS27595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTB_RS27605	COG2197	response regulator
BTB_RS27610	COG4585	Histidine kinase
BTB_RS27610	COG2203	Gaf domain
BTB_RS27615	COG0351	phosphomethylpyrimidine kinase
BTB_RS27620	COG3706	GGDEF domain
BTB_RS27625	COG2879	small protein
BTB_RS27630	COG1966	Carbon starvation protein
BTB_RS27635	COG3279	Response regulator of the LytR AlgR family
BTB_RS27640	COG0477	Major facilitator Superfamily
BTB_RS27650	COG0438	transferase activity, transferring glycosyl groups
BTB_RS27665	COG0840	transmembrane signaling receptor activity
BTB_RS27675	COG1607	acyl-coa hydrolase
BTB_RS27680	COG1216	Glycosyl transferase, family 2
BTB_RS27690	COG1216	Glycosyl transferase, family 2
BTB_RS27700	COG4485	Bacterial membrane protein, YfhO
BTB_RS27705	COG0463	Glycosyl transferase, family 2
BTB_RS27715	COG1309	transcriptional regulator
BTB_RS27720	COG0488	(ABC) transporter
BTB_RS27725	COG1309	transcriptional regulator
BTB_RS27730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTB_RS27735	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTB_RS27735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTB_RS27740	COG0628	permease
BTB_RS27760	COG3275	phosphorelay sensor kinase activity
BTB_RS27765	COG2814	Major facilitator Superfamily
BTB_RS27770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTB_RS27775	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BTB_RS27800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTB_RS27805	COG1272	protein, Hemolysin III
BTB_RS27825	COG1164	Oligoendopeptidase f
BTB_RS27835	COG5002	protein histidine kinase activity
BTB_RS27850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTB_RS27855	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BTB_RS27860	COG4853	Protein conserved in bacteria
BTB_RS27870	COG5002	protein histidine kinase activity
BTB_RS27875	COG0745	RESPONSE REGULATOR receiver
BTB_RS27905	COG0305	Participates in initiation and elongation during chromosome replication
BTB_RS27915	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BTB_RS27920	COG4241	membrane
BTB_RS27930	COG0629	single-stranded DNA binding
BTB_RS27940	COG0012	GTP binding
BTB_RS27945	COG4481	Protein conserved in bacteria
BTB_RS27950	COG0668	transmembrane transport
BTB_RS27960	COG1475	DNA binding
BTB_RS27965	COG1192	Involved in chromosome partitioning
BTB_RS27990	COG1847	R3H domain protein
BTB_RS27995	COG0706	membrane insertase activity
BTB_RS28005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BTB_RS28225	COG1982	Orn Lys Arg decarboxylase major
BTB_RS28380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTB_RS28555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTB_RS28570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BTB_RS29050	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BTB_RS29090	COG0489	protein tyrosine kinase activity
BTB_RS29225	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BTB_RS29390	COG0277	FAD linked oxidase domain protein
BTB_RS29435	COG0601	transmembrane transport
BTB_RS29495	COG0747	negative chemotaxis
BTB_RS29570	COG0697	spore germination
BTB_RS29585	COG0204	Acyl-transferase
BTB_RS29625	COG5298	Protein conserved in bacteria
BTB_RS29945	COG0488	(ABC) transporter
BTB_RS30030	COG2252	PERMEase
BTB_RS30780	COG2309	aminopeptidase activity
BTB_RS30845	COG1473	amidohydrolase
BTB_RS31015	COG1126	abc transporter atp-binding protein
BTB_RS31205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTB_RS31340	COG1295	ribonuclease BN
BTB_RS31410	COG3871	stress protein (general stress protein 26)
BTB_RS31445	COG3829	transcription factor binding
BTB_RS31530	COG1882	Formate acetyltransferase
BTB_RS31750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTB_RS32085	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTB_RS32115	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTB_RS32145	COG0187	DNA topoisomerase II activity
BTB_RS32190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTB_RS32195	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTB_RS32240	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTB_RS32260	COG0187	DNA topoisomerase II activity
BTB_RS32270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTB_RS32280	COG2376	Dihydroxyacetone kinase
BTB_RS32305	COG0187	DNA topoisomerase II activity