locus-tag class description FOC86_RS00165 ENOG4105K4H Nlp p60 protein FOC86_RS00240 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC86_RS00270 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC86_RS00295 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC86_RS00320 ENOG4105DVF Cytosine-specific methyltransferase FOC86_RS00325 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC86_RS00360 ENOG4107QJE Chromosome Partitioning Protein FOC86_RS00390 ENOG4105EWC Purine nucleoside phosphorylase FOC86_RS00435 ENOG4105EMD TRANSCRIPTIONal FOC86_RS00440 ENOG4105VCP PTS System FOC86_RS00445 ENOG4105VZJ PTS System FOC86_RS00465 ENOG41069ER domain protein FOC86_RS00470 ENOG4107RBB ABC transporter, permease FOC86_RS00475 ENOG4105C19 ABC transporter FOC86_RS00505 ENOG4105WEF catalase FOC86_RS00540 ENOG4107T5V SNARE associated Golgi FOC86_RS00575 ENOG4105CUB amino acid FOC86_RS00580 ENOG4107RWR Sodium hydrogen exchanger FOC86_RS00590 ENOG4106KNT transcriptional regulator FOC86_RS00630 ENOG4108YXU transcriptional regulator AsnC family FOC86_RS00645 ENOG4105KPY Small multidrug resistance protein FOC86_RS00670 ENOG4105NF4 modulator of drug activity FOC86_RS00675 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FOC86_RS00680 ENOG4105E5W Transporter FOC86_RS00690 ENOG4107RKG DJ-1/PfpI family FOC86_RS00695 ENOG4105CH6 catalase FOC86_RS00705 ENOG4105D5Q Arginine ornithine antiporter FOC86_RS00710 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FOC86_RS00720 ENOG4105C26 Dehydrogenase FOC86_RS00725 ENOG4105BZ1 (ABC) transporter FOC86_RS00730 ENOG4105BZ1 (ABC) transporter FOC86_RS00740 ENOG4105DRP amino acid AbC transporter FOC86_RS00745 ENOG4105CDA abc transporter atp-binding protein FOC86_RS00760 ENOG410839P FOC86_RS00795 ENOG4107FQX Alpha-acetolactate decarboxylase FOC86_RS00815 ENOG4105D4P Coproporphyrinogen iii oxidase FOC86_RS00830 ENOG4105CHH sulfate transporter FOC86_RS00870 ENOG4105IEH endo-beta-N-acetylglucosaminidase FOC86_RS00885 ENOG4105CGU Enoyl-CoA hydratase FOC86_RS00905 ENOG4105DER m42 family FOC86_RS00950 ENOG4108IBT Inherit from COG: transposase FOC86_RS01030 ENOG4105F32 YngK protein FOC86_RS01070 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC86_RS01080 ENOG4108JQ7 (ABC) transporter FOC86_RS01110 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FOC86_RS01135 ENOG4105CSH Transporter FOC86_RS01145 ENOG4108MRH transcriptional regulatory protein FOC86_RS01200 ENOG4105CDU Replicative dna helicase FOC86_RS01340 ENOG4105CID antiterminator FOC86_RS01345 ENOG4105C5Y PTS System FOC86_RS01350 ENOG4105CS2 ec 3.2.1.21 FOC86_RS01360 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC86_RS01390 ENOG4105CMT Dihydroxyacetone kinase FOC86_RS01400 ENOG4105CMT Dihydroxyacetone kinase FOC86_RS01435 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FOC86_RS01505 ENOG4105WN5 stage II sporulation protein FOC86_RS01515 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_RS01525 ENOG4108MJI response regulator FOC86_RS01530 ENOG4105BZU Histidine kinase FOC86_RS01535 ENOG4105BZU Histidine kinase FOC86_RS01570 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_RS01615 ENOG4107VRP DNA repair exonuclease FOC86_RS01620 ENOG4106D4I domain protein FOC86_RS01655 ENOG4108MUZ hydrolase FOC86_RS01685 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FOC86_RS01700 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FOC86_RS01720 ENOG4105EMN RNA polymerase sigma factor FOC86_RS01730 ENOG4105CNI cell division protein FtsW FOC86_RS01745 ENOG4105C57 major facilitator superfamily FOC86_RS01750 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC86_RS01760 ENOG4105EEM helicase FOC86_RS01765 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC86_RS01790 ENOG4105K59 histidine triad (HIT) protein FOC86_RS01825 ENOG410905X membrane-flanked domain protein FOC86_RS01830 ENOG4105CKV Membrane FOC86_RS01860 ENOG410905X membrane-flanked domain protein FOC86_RS01865 ENOG4105CKV Membrane FOC86_RS01870 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation FOC86_RS01875 ENOG4105BZ4 penicillin-binding protein FOC86_RS01890 ENOG4105C1Q protoporphyrinogen oxidase FOC86_RS01920 ENOG4105ECB domain protein FOC86_RS01940 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) FOC86_RS01950 ENOG4105D29 Helix-turn-helix type 11 domain protein FOC86_RS01960 ENOG4106AXD FOC86_RS01965 ENOG4108RQ5 Beta-lactamase domain-containing protein FOC86_RS01970 ENOG4105DF9 Lipoate-protein, ligase FOC86_RS01980 ENOG4105CEY Amp-dependent synthetase and ligase FOC86_RS02000 ENOG4107RN3 metallophosphoesterase FOC86_RS02005 ENOG4107TVP HD domain protein FOC86_RS02015 ENOG4108AEY RNA polymerase sigma factor FOC86_RS02020 ENOG41086D8 Transcriptional regulator FOC86_RS02040 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_RS02065 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 FOC86_RS02090 ENOG4107QP3 malate synthase g FOC86_RS02120 ENOG4105XVF Competence transcription factor FOC86_RS02125 ENOG4105BZU Histidine kinase FOC86_RS02200 ENOG4105ERH Fumarylacetoacetate hydrolase FOC86_RS02225 ENOG4105CAQ asparagine synthetase FOC86_RS02235 ENOG4105CH6 catalase FOC86_RS02240 ENOG4105BZU Histidine kinase FOC86_RS02265 ENOG4105QNR S1 RNA binding domain protein FOC86_RS02270 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC86_RS02280 ENOG4107AYK membrAne FOC86_RS02285 ENOG41073B9 FOC86_RS02295 ENOG4108KP7 hydrolase FOC86_RS02305 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FOC86_RS02330 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC86_RS02335 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FOC86_RS02350 ENOG4105C31 Tryptophanyl-tRNA synthetase FOC86_RS02365 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC86_RS02370 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC86_RS02380 ENOG4108JQ7 (ABC) transporter FOC86_RS02385 ENOG4105UQX Mate efflux family protein FOC86_RS02405 ENOG4108ZCF integral membrane protein FOC86_RS02415 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC86_RS02425 ENOG4105DPN Oligoendopeptidase f FOC86_RS02440 ENOG4108Z18 K06886 hemoglobin FOC86_RS02445 ENOG4105MIX Adenylate cyclase FOC86_RS02465 ENOG4105EMS pseudouridine synthase FOC86_RS02485 ENOG4105K64 Glycosyl transferase, family 2 FOC86_RS02505 ENOG4107TVC Glycosyl transferase, family 2 FOC86_RS02525 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FOC86_RS02530 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase FOC86_RS02540 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase FOC86_RS02615 ENOG4105CK7 Sodium proline symporter FOC86_RS02625 ENOG4105DDQ anthranilate synthase FOC86_RS02705 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FOC86_RS02725 ENOG4105C7S Dehydrogenase FOC86_RS02735 ENOG4105VZ8 Transcriptional regulator FOC86_RS02780 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) FOC86_RS02790 ENOG4105DZ1 carboxypeptidase FOC86_RS02795 ENOG4105VFR signal peptidase FOC86_RS02830 ENOG4105C26 Dehydrogenase FOC86_RS02840 ENOG4105F38 ABC transporter, permease FOC86_RS02845 ENOG4105D38 putrescine abc transporter FOC86_RS02850 ENOG4107RUE extracellular solute-binding protein family 1 FOC86_RS02860 ENOG4105EYF MMPL domain protein FOC86_RS02870 ENOG4108YBP pseudouridine synthase FOC86_RS02880 ENOG4105K4I Scp-like extracellular FOC86_RS02885 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FOC86_RS02890 ENOG4105CQB FAD linked oxidase domain protein FOC86_RS02905 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_RS02910 ENOG4105BZU Histidine kinase FOC86_RS02915 ENOG4105JXH GntR family transcriptional regulator FOC86_RS02935 ENOG4106A3R peptidase FOC86_RS02945 ENOG4108QTI )-transporter FOC86_RS02950 ENOG4107TS3 membrane protein, TerC FOC86_RS02955 ENOG4105CZN Potassium uptake protein FOC86_RS02960 ENOG410681C small acid-soluble spore protein FOC86_RS02965 ENOG4108Z7G MaoC domain protein dehydratase FOC86_RS02985 ENOG4105CHR reductase FOC86_RS02995 ENOG4105MWK D-amino acid dehydrogenase, small subunit FOC86_RS03015 ENOG4105C4Y ABC transporter FOC86_RS03020 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC86_RS03025 ENOG4107RCV ABC transporter, permease FOC86_RS03045 ENOG4105E98 transcriptional regulator DeoR family FOC86_RS03055 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) FOC86_RS03065 ENOG4105PXI polysaccharide deacetylase FOC86_RS03075 ENOG4105BZU Histidine kinase FOC86_RS03080 ENOG41090MY MarR family Transcriptional regulator FOC86_RS03090 ENOG4106DF1 FOC86_RS03095 ENOG4105BZU Histidine kinase FOC86_RS03105 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase FOC86_RS03110 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FOC86_RS03150 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) FOC86_RS03170 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FOC86_RS03175 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC86_RS03180 ENOG4105CZV ABC transporter FOC86_RS03190 ENOG4105CJ1 ABC, transporter FOC86_RS03230 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC86_RS03235 ENOG4105EA8 2-Nitropropane dioxygenase FOC86_RS03240 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC86_RS03250 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FOC86_RS03275 ENOG4105NQC Flavodoxin FOC86_RS03345 ENOG4105CZN Potassium uptake protein FOC86_RS03350 ENOG41063Y9 FOC86_RS03355 ENOG4105KBJ sporulation protein ytfj FOC86_RS03375 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC86_RS03380 ENOG4105C7K acetolactate synthase FOC86_RS03385 ENOG4108ZP8 Acetolactate synthase small subunit FOC86_RS03460 ENOG4107RVV histidinol phosphate phosphatase, hisj family FOC86_RS03475 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC86_RS03480 ENOG4105E0M Sulfatase FOC86_RS03490 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FOC86_RS03510 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) FOC86_RS03515 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FOC86_RS03525 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC86_RS03530 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC86_RS03535 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC86_RS03540 ENOG4105C8J )-transporter FOC86_RS03570 ENOG4105DFD Na H antiporter FOC86_RS03590 ENOG4105ENE Histidine kinase FOC86_RS03595 ENOG4105WH1 Two component transcriptional regulator luxr family FOC86_RS03615 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) FOC86_RS03660 ENOG4105CJ3 phosphate transporter FOC86_RS03665 ENOG4107GRR phosphate transport regulator FOC86_RS03670 ENOG4105BZ4 penicillin-binding protein FOC86_RS03685 ENOG4105BZU Histidine kinase FOC86_RS03690 ENOG4105I3N Conserved Protein FOC86_RS03705 ENOG4105BZU Histidine kinase FOC86_RS03740 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC86_RS03745 ENOG4105DZ1 carboxypeptidase FOC86_RS03750 ENOG4108JIC nucleoside recognition domain protein FOC86_RS03760 ENOG4105FE9 pseudouridine synthase FOC86_RS03770 ENOG4107TWT Cytochrome c biogenesis protein FOC86_RS03775 ENOG4105CRE cytochrome C FOC86_RS03780 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_RS03785 ENOG4105BZU Histidine kinase FOC86_RS03790 ENOG4108WBT adenosyltransferase FOC86_RS03795 ENOG41063SB peptidase FOC86_RS03805 ENOG4108SAX Membrane FOC86_RS03820 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC86_RS03825 ENOG4105I7S Abortive infection protein FOC86_RS03835 ENOG4107RGJ metallophosphoesterase FOC86_RS03840 ENOG4107X2D transcriptional regulator, merr family FOC86_RS03845 ENOG4108S6Z Negative regulator of genetic competence FOC86_RS03870 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase FOC86_RS03875 ENOG4105HDK L-asparaginase FOC86_RS03910 ENOG4105S2F FOC86_RS03915 ENOG41065D1 FOC86_RS03945 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) FOC86_RS03960 ENOG4105XXQ heptaprenyl diphosphate synthase component I FOC86_RS03970 ENOG4105EAH synthase FOC86_RS03995 ENOG41068YB TPR repeat-containing protein FOC86_RS04010 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) FOC86_RS04015 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FOC86_RS04020 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit FOC86_RS04050 ENOG4108JYZ YitT family FOC86_RS04055 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase FOC86_RS04070 ENOG4105FJR Lmbe family FOC86_RS04075 ENOG4105CPK Glycosyl transferase (Group 1 FOC86_RS04110 ENOG4105DVT helicase FOC86_RS04115 ENOG4105YAC FOC86_RS04135 ENOG4105CSM endonuclease III FOC86_RS04145 ENOG4105BZ4 penicillin-binding protein FOC86_RS04205 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FOC86_RS04215 ENOG4105DVT helicase FOC86_RS04220 ENOG4105CTD carboxy-peptidase FOC86_RS04235 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC86_RS04245 ENOG4105C2W permease FOC86_RS04250 ENOG4105DHF Membrane FOC86_RS04255 ENOG410890F Dynamin family FOC86_RS04265 ENOG4108W0I acetyltransferase FOC86_RS04275 ENOG4105KHC sulfurtransferase FOC86_RS04305 ENOG4106032 Glutathionylspermidine synthase FOC86_RS04365 ENOG4105CPK Glycosyl transferase (Group 1 FOC86_RS04380 ENOG4108SZE gCN5-related N-acetyltransferase FOC86_RS04400 ENOG41081VK Ribonuclease FOC86_RS04465 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC86_RS04475 ENOG4107RWR Sodium hydrogen exchanger FOC86_RS04480 ENOG4105CN5 Metallo-Beta-Lactamase FOC86_RS04485 ENOG4108Z5V transcriptional regulator, merr family FOC86_RS04495 ENOG4105H67 Protein of unknown function (DUF421) FOC86_RS04500 ENOG41080C8 DUF218 domain FOC86_RS04565 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FOC86_RS04580 ENOG4107R0U MotA TolQ exbB proton channel FOC86_RS04585 ENOG4105ER2 Ompa motb domain protein FOC86_RS04590 ENOG4107YTP response regulator receiver protein FOC86_RS04595 ENOG4105CBS Chea signal transduction histidine kinase FOC86_RS04600 ENOG4105DD5 Flagellar motor switch protein FOC86_RS04615 ENOG4105BZU Histidine kinase FOC86_RS04635 ENOG4105E1Q flagellar hook-associated protein FOC86_RS04640 ENOG4105DTJ flagellar hook-associated protein FOC86_RS04645 ENOG4107TPX flagellar hook-associated FOC86_RS04660 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FOC86_RS04665 ENOG4108ZC9 flagellar basal-body rod protein flgc FOC86_RS04675 ENOG4107U2N Flagellar M-ring protein FOC86_RS04680 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOC86_RS04710 ENOG4105BZE flagellar hook protein, FlgE FOC86_RS04725 ENOG4107R88 Chemotaxis protein (CheV) FOC86_RS04735 ENOG4105I03 Flagellin FOC86_RS04740 ENOG4105I03 Flagellin FOC86_RS04745 ENOG4105E4C Lytic transglycosylase catalytic FOC86_RS04755 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOC86_RS04760 ENOG4105DD5 Flagellar motor switch protein FOC86_RS04770 ENOG4105CN7 Flagellar biosynthetic protein FliP FOC86_RS04775 ENOG4105VS8 Flagellar biosynthetic protein fliq FOC86_RS04785 ENOG4105D00 flagellar biosynthetic protein flhB FOC86_RS04790 ENOG4105D7B Flagellar biosynthesis protein flha FOC86_RS04795 ENOG4105FZW flagellar biosynthesis regulator FlhF FOC86_RS04800 ENOG4105KTQ flagellar basal-body rod protein FOC86_RS04805 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC86_RS04840 ENOG4105KAC Antibiotic biosynthesis monooxygenase FOC86_RS04870 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC86_RS04875 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FOC86_RS04880 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component FOC86_RS04885 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FOC86_RS04925 ENOG4105CVJ phosphoglycerate mutase FOC86_RS04945 ENOG4105K56 Transcriptional regulator FOC86_RS04955 ENOG4105CAQ asparagine synthetase FOC86_RS04985 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FOC86_RS05000 ENOG4105DQ6 Transposase FOC86_RS05045 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC86_RS05065 ENOG4105PGM cation diffusion facilitator family transporter FOC86_RS05075 ENOG4105DRR Transcriptional regulator, GntR family FOC86_RS05080 ENOG4108UZ3 Transporter FOC86_RS05085 ENOG4105CKI cobalamin synthesis protein FOC86_RS05090 ENOG4108PJD permease FOC86_RS05105 ENOG4105DFD Na H antiporter FOC86_RS05110 ENOG4105VUF Transcriptional regulator FOC86_RS05120 ENOG4105C9Q fumarate hydratase class II FOC86_RS05135 ENOG4105C5X domain protein FOC86_RS05145 ENOG4107QJQ Mate efflux family protein FOC86_RS05150 ENOG4105EC3 peptidase S51, dipeptidase E FOC86_RS05170 ENOG4107QIV Cytochrome c biogenesis protein FOC86_RS05200 ENOG4106BRA Membrane FOC86_RS05235 ENOG4105CJ1 ABC, transporter FOC86_RS05265 ENOG4108IBT Inherit from COG: transposase FOC86_RS05275 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FOC86_RS05285 ENOG4108IJ0 Aspartate ammonia-lyase FOC86_RS05290 ENOG4105C6K Malic enzyme FOC86_RS05350 ENOG4105FVX FOC86_RS05380 ENOG4105CSR polyphosphate kinase 2 FOC86_RS05385 ENOG4105U3E Transcriptional regulator FOC86_RS05395 ENOG4105DXI Major Facilitator superfamily FOC86_RS05410 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOC86_RS05420 ENOG4105EU0 Major facilitator Superfamily FOC86_RS05425 ENOG4105C6T cysteine synthase FOC86_RS05445 ENOG4105C8J )-transporter FOC86_RS05455 ENOG4105X5K response regulator receiver protein FOC86_RS05460 ENOG4105H67 Protein of unknown function (DUF421) FOC86_RS05475 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FOC86_RS05480 ENOG4105CHR reductase FOC86_RS05485 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC86_RS05490 ENOG4105C7K acetolactate synthase FOC86_RS05495 ENOG4108ZP8 Acetolactate synthase small subunit FOC86_RS05510 ENOG4105C7B Threonine dehydratase FOC86_RS05535 ENOG4105C6X Major Facilitator FOC86_RS05540 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FOC86_RS05550 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FOC86_RS05555 ENOG4105DY9 regulatoR FOC86_RS05560 ENOG4105CYC Transferase FOC86_RS05580 ENOG4105F6J Alpha beta hydrolase fold FOC86_RS05615 ENOG41068WN FOC86_RS05635 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) FOC86_RS05685 ENOG4107RHR regulatoR FOC86_RS05695 ENOG4105D9N nucleoside FOC86_RS05700 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) FOC86_RS05730 ENOG4107RAQ aminopeptidase FOC86_RS05735 ENOG4107R16 Multicopper oxidase FOC86_RS05790 ENOG4108T5E Copper resistance protein FOC86_RS05795 ENOG4105KTB nuclear export factor GLE1 FOC86_RS05805 ENOG4107RT3 EamA-like transporter family FOC86_RS05810 ENOG4105GZI Transcriptional regulator FOC86_RS05815 ENOG4108Z40 Transcriptional regulator FOC86_RS05820 ENOG4107ZXU DSBA oxidoreductase FOC86_RS05825 ENOG4108TVJ Nitroreductase FOC86_RS05830 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FOC86_RS05835 ENOG4106F5Q Membrane FOC86_RS05850 ENOG4105CKI cobalamin synthesis protein FOC86_RS05860 ENOG4105C0Z ABC transporter FOC86_RS05865 ENOG4108IV0 ABC, transporter FOC86_RS05870 ENOG4105C32 Amino acid ABC transporter (Permease) FOC86_RS05880 ENOG4105SKE transcriptional Regulator LysR family FOC86_RS05910 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC86_RS05915 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC86_RS05920 ENOG4108JJ9 ABC, transporter FOC86_RS05925 ENOG4108JJ8 (ABC) transporter FOC86_RS05940 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC86_RS05970 ENOG4105BZ1 (ABC) transporter FOC86_RS05975 ENOG4105EFI regulatoR FOC86_RS05980 ENOG4105BZU Histidine kinase FOC86_RS06000 ENOG41075D4 Aminoglycoside 6-adenylyltransferase FOC86_RS06010 ENOG4106AKJ FOC86_RS06025 ENOG4105D6E homoserine dehydrogenase FOC86_RS06050 ENOG4108KGH TRANSCRIPTIONal FOC86_RS06060 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_RS06065 ENOG4105BZU Histidine kinase FOC86_RS06080 ENOG4105KT7 mgtC SapB transporter FOC86_RS06085 ENOG4105VRR gCN5-related N-acetyltransferase FOC86_RS06095 ENOG4105DUU IucA IucC family protein FOC86_RS06100 ENOG4105CEY Amp-dependent synthetase and ligase FOC86_RS06115 ENOG4108WBH protein TIM barrel FOC86_RS06120 ENOG4105YWU small acid-soluble spore protein FOC86_RS06130 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FOC86_RS06180 ENOG4105KRN Transcriptional regulator, abrb family FOC86_RS06190 ENOG4105YVS arsR family transcriptional regulator FOC86_RS06195 ENOG4107SET aldo keto reductase FOC86_RS06200 ENOG4107XZQ multidrug resistance protein FOC86_RS06225 ENOG4105C8Q Methyl-accepting chemotaxis FOC86_RS06240 ENOG4108K88 Membrane FOC86_RS06245 ENOG4108WPJ Ferritin-like domain FOC86_RS06260 ENOG4105DEN Luciferase family FOC86_RS06275 ENOG4105VMI -acetyltransferase FOC86_RS06280 ENOG4107QM2 Aldo Keto reductase FOC86_RS06285 ENOG4105CKI cobalamin synthesis protein FOC86_RS06295 ENOG4105DSE periplasmic solute binding protein FOC86_RS06305 ENOG4105K4T epimerase FOC86_RS06315 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC86_RS06340 ENOG4107TB6 phosphoglycerate mutase FOC86_RS06360 ENOG4107T5V SNARE associated Golgi FOC86_RS06375 ENOG4108PJD permease FOC86_RS06385 ENOG4108S4H thioesterase Superfamily protein FOC86_RS06395 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC86_RS06415 ENOG4105SXS Protein of unknown function (DUF456) FOC86_RS06420 ENOG4105C37 (CBS) domain FOC86_RS06440 ENOG4108Z7R Chaperone CsaA FOC86_RS06460 ENOG4108ZRV stage ii sporulation protein p FOC86_RS06470 ENOG4108VXD carboxy-peptidase FOC86_RS06475 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FOC86_RS06480 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FOC86_RS06505 ENOG4108X4Q Hydrolase FOC86_RS06515 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC86_RS06535 ENOG41087PP glycosyltransferase MGT family FOC86_RS06540 ENOG4108JYZ YitT family FOC86_RS06545 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC86_RS06575 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC86_RS06615 ENOG4108MGT Required for secretion of EsxA and EsxB FOC86_RS06695 ENOG4105KBJ sporulation protein ytfj FOC86_RS06720 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FOC86_RS06745 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FOC86_RS06755 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FOC86_RS06760 ENOG4105EMN RNA polymerase sigma factor FOC86_RS06775 ENOG4105CNW domain protein FOC86_RS06785 ENOG4108V06 Glutathione peroxidase FOC86_RS06800 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC86_RS06810 ENOG4108IUE nitrate reductase beta subunit FOC86_RS06815 ENOG4105R3A Nitrate reductase FOC86_RS06825 ENOG4107V6Q Cyclic nucleotide-binding domain FOC86_RS06830 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC86_RS06835 ENOG4105D06 uba thif-type nad fad binding protein FOC86_RS06840 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC86_RS06845 ENOG4108ZAF Molybdopterin FOC86_RS06865 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC86_RS06870 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC86_RS06875 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC86_RS06880 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit FOC86_RS06885 ENOG4108IFG nitrite reductase, (NAD(P)H) FOC86_RS06890 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) FOC86_RS06930 ENOG4105MCT stage V sporulation protein S FOC86_RS06955 ENOG4105C5H ABC transporter FOC86_RS06970 ENOG4108UUM single-stranded DNA-binding protein FOC86_RS07000 ENOG4107YX5 Pfam:DUF548 FOC86_RS07035 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FOC86_RS07040 ENOG4105C5S asparaginyl-tRNA synthetase FOC86_RS07045 ENOG4105C8J )-transporter FOC86_RS07065 ENOG4107XGZ Hydrolase FOC86_RS07070 ENOG4105CY2 Citrate transporter FOC86_RS07075 ENOG4105C0A alcohol dehydrogenase FOC86_RS07090 ENOG4105KD7 acetyltransferase FOC86_RS07095 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FOC86_RS07120 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 FOC86_RS07140 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) FOC86_RS07160 ENOG4107RVG penicillin-binding protein FOC86_RS07180 ENOG4105E9Q Acyl-transferase FOC86_RS07185 ENOG4108UT2 hemolysin iii FOC86_RS07195 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FOC86_RS07205 ENOG4108RCR degv family FOC86_RS07210 ENOG4105E8R UPF0173 metal-dependent hydrolase FOC86_RS07215 ENOG4108KF3 Electron transport protein SCO1 SenC FOC86_RS07220 ENOG4107Y70 Heat shock protein FOC86_RS07225 ENOG4105CAQ asparagine synthetase FOC86_RS07240 ENOG4108MES Periplasmic binding protein FOC86_RS07245 ENOG4105F0I Aminotransferase FOC86_RS07275 ENOG4107Y70 Heat shock protein FOC86_RS07280 ENOG4105D8X mechanosensitive ion channel FOC86_RS07285 ENOG4105BZU Histidine kinase FOC86_RS07290 ENOG4105WH1 Two component transcriptional regulator luxr family FOC86_RS07325 ENOG4105CMG Carbohydrate kinase FOC86_RS07330 ENOG4105CMG Carbohydrate kinase FOC86_RS07360 ENOG4108IJ8 ABC transporter FOC86_RS07365 ENOG4105E90 ABC transporter FOC86_RS07400 ENOG4105C37 (CBS) domain FOC86_RS07425 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC86_RS07440 ENOG4107S4Y M20 DapE family protein YgeY FOC86_RS07445 ENOG4108TSC N-acetyltransferase FOC86_RS07450 ENOG4108JUB Transcriptional regulator FOC86_RS07455 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FOC86_RS07495 ENOG4108N23 SpoOM-related protein FOC86_RS07500 ENOG410841Q phosphoesterase PA-phosphatase related protein FOC86_RS07510 ENOG4105SZ6 Thioredoxin FOC86_RS07525 ENOG4108IBT Inherit from COG: transposase FOC86_RS07630 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC86_RS07670 ENOG4105BZ4 penicillin-binding protein FOC86_RS07675 ENOG4105CZM Major Facilitator FOC86_RS07680 ENOG4105W8X HesB YadR YfhF-family protein FOC86_RS07690 ENOG4105DXD 2-methylcitrate dehydratase FOC86_RS07695 ENOG4105CR4 methylisocitrate lyase FOC86_RS07700 ENOG4105C1G acyl-Coa dehydrogenase FOC86_RS07705 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOC86_RS07715 ENOG4105N14 lysine exporter protein LysE YggA FOC86_RS07720 ENOG4105E39 Enoyl-CoA hydratase FOC86_RS07735 ENOG4107RFY SbcCD D subunit FOC86_RS07740 ENOG4105EYH Exonuclease FOC86_RS07765 ENOG4105FCD Major Facilitator FOC86_RS07770 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FOC86_RS07775 ENOG4105E4F Isochorismate synthase FOC86_RS07780 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FOC86_RS07785 ENOG4105WQI isochorismatase FOC86_RS07790 ENOG4105CEY Amp-dependent synthetase and ligase FOC86_RS07795 ENOG4105WQT MbtH domain protein FOC86_RS07800 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC86_RS07815 ENOG4105K70 DNA-binding protein FOC86_RS07835 ENOG4105BZG amino acid carrier protein FOC86_RS07855 ENOG4105FE9 pseudouridine synthase FOC86_RS07860 ENOG4105C22 threonyL-tRNA synthetase FOC86_RS07865 ENOG4105C19 ABC transporter FOC86_RS07875 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FOC86_RS07895 ENOG4108D32 Methyltransferase FOC86_RS07915 ENOG41081I9 integral membrane protein FOC86_RS07930 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FOC86_RS07940 ENOG4105EYF MMPL domain protein FOC86_RS07965 ENOG4105WCN acetyltransferase FOC86_RS07985 ENOG4107TSN permease FOC86_RS08000 ENOG4108QY0 Membrane FOC86_RS08005 ENOG410900G Protein of unknown function (DUF421) FOC86_RS08010 ENOG4108QY0 Membrane FOC86_RS08020 ENOG4107UGY Proline imino-peptidase FOC86_RS08035 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOC86_RS08045 ENOG4108MEK Metal-binding protein YodA FOC86_RS08050 ENOG4105CN5 Metallo-Beta-Lactamase FOC86_RS08055 ENOG4107YZX Universal stress protein FOC86_RS08060 ENOG4105CHH sulfate transporter FOC86_RS08070 ENOG4105VUN Transcriptional regulator FOC86_RS08125 ENOG4105C1Q protoporphyrinogen oxidase FOC86_RS08135 ENOG41068WN FOC86_RS08145 ENOG4105VEQ Cold shock protein FOC86_RS08215 ENOG4107V2S Transcriptional regulator FOC86_RS08220 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC86_RS08235 ENOG4105DND Transcriptional regulator FOC86_RS08240 ENOG4108RPX mosc domain containing protein FOC86_RS08255 ENOG4105BZ1 (ABC) transporter FOC86_RS08260 ENOG4105BZ1 (ABC) transporter FOC86_RS08280 ENOG4108JCI Transcriptional regulator FOC86_RS08315 ENOG4108KJ0 anaerobic glycerol-3-phosphate dehydrogenase, subunit B FOC86_RS08320 ENOG4108KPJ rna polymerase sigma factor FOC86_RS08345 ENOG4105F32 YngK protein FOC86_RS08370 ENOG4105RD7 BadF BadG BcrA BcrD FOC86_RS08380 ENOG4107STF Involved in phosphonate degradation (By similarity) FOC86_RS08415 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FOC86_RS08425 ENOG4105C1J atp-dependent rna helicase FOC86_RS08440 ENOG4108RZE Tetr family transcriptional regulator FOC86_RS08460 ENOG41088CC tellurite resistance protein tehB FOC86_RS08470 ENOG4108I0C methyltransferase FOC86_RS08475 ENOG4107RA9 decarboxylase FOC86_RS08480 ENOG41090HR transcriptional regulator FOC86_RS08505 ENOG4105CIN aminoacyl-histidine dipeptidase FOC86_RS08530 ENOG4107RF6 penicillin-binding protein FOC86_RS08535 ENOG4107RF6 penicillin-binding protein FOC86_RS08545 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOC86_RS08550 ENOG4105ETE Transcriptional regulator (LacI family FOC86_RS08555 ENOG4105IE8 Alpha-ketoglutarate permease FOC86_RS08560 ENOG4105CK5 oxidoreductase FOC86_RS08585 ENOG4105D2N Aldolase FOC86_RS08590 ENOG4105DH8 myo-inositol catabolism FOC86_RS08605 ENOG4105CGH 5'-nucleotidase FOC86_RS08620 ENOG4105VZ8 Transcriptional regulator FOC86_RS08650 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity FOC86_RS08655 ENOG41067SE Tetr family transcriptional regulator FOC86_RS08660 ENOG4105C5H ABC transporter FOC86_RS08665 ENOG4105BZU Histidine kinase FOC86_RS08690 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) FOC86_RS08705 ENOG4105CJ1 ABC, transporter FOC86_RS08715 ENOG4107Z3H Transcriptional regulator, TetR family FOC86_RS08730 ENOG4105C1G acyl-Coa dehydrogenase FOC86_RS08735 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC86_RS08740 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit FOC86_RS08745 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FOC86_RS08750 ENOG4105E39 Enoyl-CoA hydratase FOC86_RS08755 ENOG4107QX3 carboxylase FOC86_RS08760 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC86_RS08770 ENOG4105WCN acetyltransferase FOC86_RS08775 ENOG4105DBI uridine monophosphokinase FOC86_RS08790 ENOG4105DZ1 carboxypeptidase FOC86_RS08805 ENOG4105T9C HD domain FOC86_RS08815 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FOC86_RS08860 ENOG4105FQP Beta-lactamase FOC86_RS08870 ENOG4107Y80 Major Facilitator superfamily FOC86_RS08890 ENOG4105CUV Homoserine Kinase FOC86_RS08950 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FOC86_RS08960 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein FOC86_RS08970 ENOG4105DK7 lysyl-tRNA synthetase FOC86_RS09035 ENOG4105D6E homoserine dehydrogenase FOC86_RS09050 ENOG4105ETU transcriptional activator (TenA FOC86_RS09120 ENOG4105CNU cell division protein FtsK FOC86_RS09130 ENOG4108TFU terminase (Small subunit) FOC86_RS09215 ENOG410667J hydrolase FOC86_RS09220 ENOG4105BZU Histidine kinase FOC86_RS09225 ENOG4107RF6 penicillin-binding protein FOC86_RS09260 ENOG4108HGU Histidine kinase FOC86_RS09270 ENOG4105RHY Pfam:UPF0157 FOC86_RS09275 ENOG4105CB2 alcohol dehydrogenase FOC86_RS09280 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOC86_RS09285 ENOG4105CJN penicillin-binding protein FOC86_RS09295 ENOG4105FQP Beta-lactamase FOC86_RS09350 ENOG4107Y80 Major Facilitator superfamily FOC86_RS09365 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC86_RS09385 ENOG4107Y9U Membrane FOC86_RS09420 ENOG4105FCD Major Facilitator FOC86_RS09435 ENOG4105E09 nadh pyrophosphatase FOC86_RS09440 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC86_RS09445 ENOG4108Z4K mutator MutT protein FOC86_RS09475 ENOG4108XI2 Domain of unknown function (DUF1963) FOC86_RS09500 ENOG4108NRW Phospholipase, patatin family FOC86_RS09505 ENOG4105KWG Pfam:DUF1696 FOC86_RS09540 ENOG4105PKS Excinuclease abc c subunit domain protein FOC86_RS09580 ENOG4107VFR oxidoreductase FOC86_RS09625 ENOG4108IUM Glycogen debranching enzyme FOC86_RS09650 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOC86_RS09660 ENOG4105FDR Membrane FOC86_RS09720 ENOG4105MSI germination protein ypeb FOC86_RS09755 ENOG4107Z3H Transcriptional regulator, TetR family FOC86_RS09785 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FOC86_RS09805 ENOG4105E98 transcriptional regulator DeoR family FOC86_RS09820 ENOG4107QKR Dehydrogenase FOC86_RS09830 ENOG4107RUY (E1 component), alpha subunit FOC86_RS09840 ENOG4105E1F short-chain dehydrogenase reductase FOC86_RS09845 ENOG4105RHY Pfam:UPF0157 FOC86_RS09850 ENOG4105DBI uridine monophosphokinase FOC86_RS09860 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FOC86_RS09885 ENOG4108IJ7 Glycine betaine FOC86_RS09915 ENOG41082BV acetyltransferase FOC86_RS09920 ENOG4108M1A Chitin-binding protein FOC86_RS09935 ENOG4105MSB protein, conserved in bacteria FOC86_RS09975 ENOG4108Z7F N-acetyltransferase FOC86_RS09995 ENOG4105EEM helicase FOC86_RS10015 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC86_RS10060 ENOG4108M1A Chitin-binding protein FOC86_RS10080 ENOG4105BZG amino acid carrier protein FOC86_RS10085 ENOG4105C26 Dehydrogenase FOC86_RS10090 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC86_RS10095 ENOG4105CTU Proline racemase FOC86_RS10100 ENOG4105CTU Proline racemase FOC86_RS10105 ENOG41080HI glycine oxidase FOC86_RS10115 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein FOC86_RS10145 ENOG4107T5V SNARE associated Golgi FOC86_RS10160 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC86_RS10165 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FOC86_RS10180 ENOG4105DTQ mandelate racemase muconate lactonizing FOC86_RS10220 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) FOC86_RS10225 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC86_RS10230 ENOG4105BZU Histidine kinase FOC86_RS10235 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_RS10255 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 FOC86_RS10270 ENOG4105DPN Oligoendopeptidase f FOC86_RS10280 ENOG4105EPR degv family FOC86_RS10320 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FOC86_RS10325 ENOG4106K7D Major facilitator family transporter FOC86_RS10345 ENOG4107BMA Transglycosylase associated protein FOC86_RS10360 ENOG41089UC methyltransferase, type 11 FOC86_RS10395 ENOG4105CHM Aminotransferase FOC86_RS10410 ENOG4108ZMI UPF0477 protein FOC86_RS10425 ENOG4105DVE abc transporter atp-binding protein FOC86_RS10475 ENOG4105C02 permease FOC86_RS10485 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FOC86_RS10490 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FOC86_RS10495 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein FOC86_RS10520 ENOG4105E09 nadh pyrophosphatase FOC86_RS10540 ENOG4108AQF aminoglycoside N(3)-acetyltransferase FOC86_RS10590 ENOG4107VC0 DNA alkylation repair enzyme FOC86_RS10610 ENOG4108ZCF integral membrane protein FOC86_RS10615 ENOG4105E0M Sulfatase FOC86_RS10620 ENOG4105C5H ABC transporter FOC86_RS10630 ENOG4105EYF MMPL domain protein FOC86_RS10635 ENOG41082JN Transcriptional regulator FOC86_RS10665 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase FOC86_RS10685 ENOG4105FFM Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein (By similarity) FOC86_RS10700 ENOG41069ER domain protein FOC86_RS10710 ENOG4105CY2 Citrate transporter FOC86_RS10715 ENOG4105E39 Enoyl-CoA hydratase FOC86_RS10720 ENOG4105J5T Amp-dependent synthetase and ligase FOC86_RS10725 ENOG4108JUB Transcriptional regulator FOC86_RS10740 ENOG4105D4B ABC, transporter FOC86_RS10750 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane FOC86_RS10760 ENOG4105DKT Transcriptional regulator FOC86_RS10765 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) FOC86_RS10775 ENOG41061GT Aldolase FOC86_RS10800 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) FOC86_RS10835 ENOG4105II7 pyrroline-5-carboxylate reductase FOC86_RS10845 ENOG4107258 Transcriptional regulator FOC86_RS10855 ENOG4105E0Y RtcB Protein FOC86_RS10860 ENOG4105ECK Fatty Acid Desaturase FOC86_RS10865 ENOG4105G6Z alkaline phosphatase FOC86_RS10875 ENOG4105VMP Transcriptional regulator FOC86_RS10890 ENOG41090T1 Membrane FOC86_RS10900 ENOG4108WCX response regulator FOC86_RS10920 ENOG4105KNA -acetyltransferase FOC86_RS10945 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC86_RS10960 ENOG4105CSH Transporter FOC86_RS10970 ENOG4105CKK Glycosyl transferase, family 2 FOC86_RS10985 ENOG4105CKK Glycosyl transferase, family 2 FOC86_RS10995 ENOG4105C8Y Acetylornithine aminotransferase FOC86_RS11045 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC86_RS11100 ENOG41090AA FOC86_RS11160 ENOG4108IBT Inherit from COG: transposase FOC86_RS11180 ENOG4108TVJ Nitroreductase FOC86_RS11185 ENOG4105FS7 Transcriptional regulator FOC86_RS11200 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FOC86_RS11220 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC86_RS11240 ENOG4105C19 ABC transporter FOC86_RS11270 ENOG4108XET gCN5-related N-acetyltransferase FOC86_RS11350 ENOG410635A Membrane FOC86_RS11355 ENOG4105KNA -acetyltransferase FOC86_RS11360 ENOG4108IQI permease FOC86_RS11370 ENOG4105F1N DNA alkylation repair FOC86_RS11400 ENOG4107RF6 penicillin-binding protein FOC86_RS11435 ENOG4105P4J Allophanate hydrolase, subunit 1 FOC86_RS11440 ENOG4107258 Transcriptional regulator FOC86_RS11450 ENOG4106N3A copper homeostasis protein cutc FOC86_RS11460 ENOG4108ZRV stage ii sporulation protein p FOC86_RS11465 ENOG4108ZHR arsR family transcriptional regulator FOC86_RS11475 ENOG4105FDT acyl-CoA dehydrogenase FOC86_RS11490 ENOG4105DWD nucleoside recognition domain protein FOC86_RS11530 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FOC86_RS11595 ENOG4105E2A Dehydrogenase FOC86_RS11605 ENOG4108IJ0 Aspartate ammonia-lyase FOC86_RS11610 ENOG4105HDK L-asparaginase FOC86_RS11615 ENOG4108IMY Transcriptional regulator FOC86_RS11635 ENOG4108B31 Spore germination protein FOC86_RS11645 ENOG4105BZU Histidine kinase FOC86_RS11670 ENOG41075H3 AraC family transcriptional regulator FOC86_RS11680 ENOG4105YWU small acid-soluble spore protein FOC86_RS11685 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FOC86_RS11690 ENOG4105CUB amino acid FOC86_RS11700 ENOG4105II7 pyrroline-5-carboxylate reductase FOC86_RS11715 ENOG4108NHD germination protein FOC86_RS11720 ENOG4108Q8B Spore germination protein FOC86_RS11740 ENOG4105CSV Glutaminase FOC86_RS11775 ENOG4105CGH 5'-nucleotidase FOC86_RS11780 ENOG4105CH6 catalase FOC86_RS11790 ENOG4105CHJ isochorismatase hydrolase FOC86_RS11855 ENOG4105DWP Membrane FOC86_RS11880 ENOG4108606 TspO/MBR family FOC86_RS11885 ENOG4105CVP deoxyribo-dipyrimidine photolyase FOC86_RS11900 ENOG4108TWJ NADH dehydrogenase subunit 5 FOC86_RS11905 ENOG4105GPN Uncharacterized conserved protein (DUF2294) FOC86_RS11920 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC86_RS11960 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC86_RS11975 ENOG4105E5W Transporter FOC86_RS12000 ENOG4105C19 ABC transporter FOC86_RS12015 ENOG4108NEV two component transcriptional regulator, LytTR family FOC86_RS12040 ENOG4105D6J arsenicaL-resistance protein FOC86_RS12045 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC86_RS12050 ENOG41085FC arsR family transcriptional regulator FOC86_RS12070 ENOG4107P5I polyketide synthase FOC86_RS12075 ENOG4108IG5 Transcriptional regulator FOC86_RS12080 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FOC86_RS12085 ENOG4108YXU transcriptional regulator AsnC family FOC86_RS12125 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FOC86_RS12130 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC86_RS12150 ENOG4105IIP Membrane FOC86_RS12190 ENOG4105K6H D-cysteine desulfhydrase FOC86_RS12235 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase FOC86_RS12245 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC86_RS12250 ENOG4105JQZ Methyltransferase FOC86_RS12265 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FOC86_RS12270 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) FOC86_RS12285 ENOG4105BZU Histidine kinase FOC86_RS12295 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC86_RS12315 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC86_RS12340 ENOG4108JQ1 Dehydrogenase FOC86_RS12360 ENOG4108AEY RNA polymerase sigma factor FOC86_RS12375 ENOG41082W1 Cupin 2, conserved barrel domain protein FOC86_RS12380 ENOG410874W AraC family transcriptional regulator FOC86_RS12395 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC86_RS12565 ENOG4106YAD MORN repeat variant FOC86_RS12670 ENOG4108ISG Major Facilitator FOC86_RS12680 ENOG4107MII Sugar-specific transcriptional regulator TrmB FOC86_RS12685 ENOG4105CZM Major Facilitator FOC86_RS12700 ENOG4105DA5 (ABC) transporter FOC86_RS12705 ENOG41069JR FOC86_RS12715 ENOG4105RXJ FOC86_RS12720 ENOG4105KPY Small multidrug resistance protein FOC86_RS12725 ENOG4105KBX Transcriptional regulator, TetR family FOC86_RS12730 ENOG4107AUC FOC86_RS12740 ENOG4105CRW Short chain fatty acid transporter FOC86_RS12750 ENOG4105DYS nad(p)h dehydrogenase (quinone) FOC86_RS12785 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FOC86_RS12810 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC86_RS12835 ENOG4108Z66 YbaK ebsC protein FOC86_RS12855 ENOG4105KVH Transcriptional regulator FOC86_RS12860 ENOG4108RCM Nitroreductase FOC86_RS12880 ENOG4108PSK reductase FOC86_RS12890 ENOG4105CJ1 ABC, transporter FOC86_RS12945 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase FOC86_RS12950 ENOG4105DKQ ROK family FOC86_RS12960 ENOG4108UW5 maltose o-acetyltransferase FOC86_RS12970 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FOC86_RS13010 ENOG4105DMQ Methyltransferase FOC86_RS13020 ENOG4105EV4 Multidrug resistance protein mdtH FOC86_RS13050 ENOG4105C37 (CBS) domain FOC86_RS13065 ENOG4105DDN Pentapeptide repeat-containing protein FOC86_RS13070 ENOG4105XDF Protein of unknown function (DUF1272) FOC86_RS13075 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) FOC86_RS13080 ENOG4105CMG Carbohydrate kinase FOC86_RS13085 ENOG4105C6Z Gluconate FOC86_RS13090 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FOC86_RS13105 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FOC86_RS13120 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone FOC86_RS13135 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FOC86_RS13140 ENOG4105D4Y metalloprotease FOC86_RS13175 ENOG4105C44 Serine transporter FOC86_RS13215 ENOG4108TZY GntR Family Transcriptional Regulator FOC86_RS13220 ENOG4105D9R oxidoreductase FOC86_RS13225 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FOC86_RS13230 ENOG4105KVH Transcriptional regulator FOC86_RS13235 ENOG4105KVH Transcriptional regulator FOC86_RS13270 ENOG4105JAB phenazine biosynthesis protein, phzf family FOC86_RS13280 ENOG4105CHR reductase FOC86_RS13295 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein FOC86_RS13300 ENOG4105KVH Transcriptional regulator FOC86_RS13360 ENOG4105KAF membrAne FOC86_RS13385 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) FOC86_RS13400 ENOG4107YXZ hydrolase, family 25 FOC86_RS13435 ENOG4105H3G oxidoreductase FOC86_RS13470 ENOG4105CIS alcohol dehydrogenase FOC86_RS13480 ENOG4105CBK multidrug resistance protein FOC86_RS13505 ENOG4108TN2 lmbE family FOC86_RS13515 ENOG4107R3E Citrate transporter FOC86_RS13530 ENOG4108MES Periplasmic binding protein FOC86_RS13535 ENOG4105EHG Permease protein FOC86_RS13540 ENOG4105DQ5 transport system permease protein FOC86_RS13545 ENOG4105NX3 Membrane FOC86_RS13550 ENOG4107ZY0 Phenazine biosynthesis-like protein FOC86_RS13570 ENOG4107CUJ Protein of unknown function (DUF2690) FOC86_RS13580 ENOG4107V2S Transcriptional regulator FOC86_RS13600 ENOG4105C98 muts2 protein FOC86_RS13610 ENOG4105E5K Alpha-amylase FOC86_RS13615 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FOC86_RS13620 ENOG4105DPN Oligoendopeptidase f FOC86_RS13625 ENOG4108A04 Beta-lactamase FOC86_RS13650 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC86_RS13660 ENOG41082BM Transcriptional regulator, arsr family FOC86_RS13665 ENOG4105CIS alcohol dehydrogenase FOC86_RS13685 ENOG4105C09 Bile acid FOC86_RS13690 ENOG4105CQB FAD linked oxidase domain protein FOC86_RS13715 ENOG4108UT6 Transferase hexapeptide repeat containing protein FOC86_RS13725 ENOG4105K64 Glycosyl transferase, family 2 FOC86_RS13730 ENOG4105E39 Enoyl-CoA hydratase FOC86_RS13740 ENOG4105KT7 mgtC SapB transporter FOC86_RS13755 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FOC86_RS13760 ENOG41073R8 VanW family FOC86_RS13770 ENOG4108R1P FOC86_RS13790 ENOG4105VEQ Cold shock protein FOC86_RS13810 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FOC86_RS13830 ENOG410904N short-chain dehydrogenase reductase FOC86_RS13840 ENOG4106IQC argininosuccinate lyase FOC86_RS13855 ENOG4108IA2 Sodium pantothenate symporter FOC86_RS13865 ENOG4105C26 Dehydrogenase FOC86_RS13870 ENOG4105CHR reductase FOC86_RS13880 ENOG4105EWU Squalene--hopene cyclase FOC86_RS13890 ENOG4105FR1 rard protein FOC86_RS13895 ENOG410696E Membrane FOC86_RS13910 ENOG4105D1F ATP-binding protein FOC86_RS13920 ENOG4108ZAF Molybdopterin FOC86_RS13925 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC86_RS13930 ENOG4105D06 uba thif-type nad fad binding protein FOC86_RS13935 ENOG4105TMB Formate nitrite transporter FOC86_RS13945 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC86_RS13950 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) FOC86_RS13960 ENOG4108JB9 formate dehydrogenase FOC86_RS13965 ENOG4105E1K spore germination protein FOC86_RS14030 ENOG4107QJT sodium dicarboxylate symporter FOC86_RS14035 ENOG4108KGH TRANSCRIPTIONal FOC86_RS14045 ENOG4105EMN RNA polymerase sigma factor FOC86_RS14055 ENOG4105CIG ABC transporter FOC86_RS14065 ENOG4105D9R oxidoreductase FOC86_RS14075 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC86_RS14080 ENOG4105K4P CoA-binding domain protein FOC86_RS14085 ENOG4105C0H protease FOC86_RS14090 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_RS14100 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase FOC86_RS14110 ENOG4105W8X HesB YadR YfhF-family protein FOC86_RS14140 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC86_RS14145 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC86_RS14155 ENOG4108JJA ABC, transporter FOC86_RS14160 ENOG4108I0Z Aconitate hydratase FOC86_RS14200 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC86_RS14220 ENOG4107F3J Amp-dependent synthetase and ligase FOC86_RS14225 ENOG4107ZYJ bioY protein FOC86_RS14230 ENOG4105CEY Amp-dependent synthetase and ligase FOC86_RS14280 ENOG4107AYK membrAne FOC86_RS14290 ENOG4105BZU Histidine kinase FOC86_RS14295 ENOG4105FBA Phospholipase Carboxylesterase FOC86_RS14300 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase FOC86_RS14305 ENOG4105CK7 Sodium proline symporter FOC86_RS14310 ENOG4105CBC glutamate synthase FOC86_RS14315 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FOC86_RS14325 ENOG4108VJ1 Transcriptional regulator (CarD family FOC86_RS14330 ENOG4108903 Formimidoylglutamase FOC86_RS14355 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) FOC86_RS14400 ENOG4107QIV Cytochrome c biogenesis protein FOC86_RS14420 ENOG4105CJ1 ABC, transporter FOC86_RS14430 ENOG4107RSM transcriptional regulator FOC86_RS14440 ENOG41067MG lrgb family FOC86_RS14485 ENOG4105BZ1 (ABC) transporter FOC86_RS14490 ENOG4105BZ1 (ABC) transporter FOC86_RS14510 ENOG4105D7V transposase FOC86_RS14535 ENOG4105CGH 5'-nucleotidase FOC86_RS14545 ENOG4108SVB resolvase FOC86_RS14565 ENOG4105K7K Transcriptional regulator FOC86_RS14570 ENOG4105C5F glutamine synthetase FOC86_RS14575 ENOG4105KV4 Transcriptional regulator FOC86_RS14580 ENOG4105CXI aluminum resistance protein FOC86_RS14585 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOC86_RS14590 ENOG4105EN6 Membrane FOC86_RS14595 ENOG4106F1P AAA ATPase, central domain protein FOC86_RS14625 ENOG41069ER domain protein FOC86_RS14630 ENOG4105DM4 PTS System FOC86_RS14635 ENOG4105DE4 1-phosphofructokinase FOC86_RS14640 ENOG4105E98 transcriptional regulator DeoR family FOC86_RS14645 ENOG4107QW4 alcohol dehydrogenase FOC86_RS14650 ENOG4108SJC Membrane FOC86_RS14660 ENOG4105C85 amino acid FOC86_RS14680 ENOG4105TMB Formate nitrite transporter FOC86_RS14685 ENOG4105K70 DNA-binding protein FOC86_RS14695 ENOG4105C59 p-type ATPase FOC86_RS14700 ENOG410681U heavy metal transport detoxification protein FOC86_RS14705 ENOG4105VPX protein, conserved in bacteria FOC86_RS14715 ENOG4105NIV Esterase FOC86_RS14720 ENOG4105E0A ABC, transporter FOC86_RS14740 ENOG4105CGK Exodeoxyribonuclease III FOC86_RS14750 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC86_RS14755 ENOG4105D03 DNA-3-methyladenine glycosylase II FOC86_RS14785 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC86_RS14790 ENOG4105BZU Histidine kinase FOC86_RS14835 ENOG4105F0V Cell wall hydrolase FOC86_RS14840 ENOG4107R6R udp-galactopyranose mutase FOC86_RS14845 ENOG4105E0M Sulfatase FOC86_RS14850 ENOG410890F Dynamin family FOC86_RS14860 ENOG4107QHE Choloylglycine hydrolase FOC86_RS14890 ENOG4105DQU oxidoreductase, subunit beta FOC86_RS14895 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein FOC86_RS14900 ENOG4108IGT Dipeptidase FOC86_RS14905 ENOG4105MCT stage V sporulation protein S FOC86_RS14910 ENOG4105D48 metallophosphoesterase FOC86_RS14935 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FOC86_RS14950 ENOG4105XZV Protein of unknown function (DUF3243) FOC86_RS14955 ENOG4108RKS Short-chain dehydrogenase reductase Sdr FOC86_RS14975 ENOG4105UIB (ABC) transporter FOC86_RS14980 ENOG4108JQ9 ABC transporter FOC86_RS14985 ENOG4105DIH basic membrane FOC86_RS14990 ENOG4105FDP GntR family transcriptional regulator FOC86_RS14995 ENOG4107QZI cell division protein FtsK FOC86_RS15005 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit FOC86_RS15015 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC86_RS15025 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC86_RS15030 ENOG4108S0H Dipicolinic acid synthetase, b subunit FOC86_RS15035 ENOG4105E35 Dipicolinate synthase subunit A FOC86_RS15045 ENOG4105C1V Peptidase, M16 FOC86_RS15065 ENOG4105DTN riboflavin biosynthesis protein ribF FOC86_RS15080 ENOG4105W7A Protein of unknown function (DUF503) FOC86_RS15090 ENOG4105VHM ribosomal protein FOC86_RS15095 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination FOC86_RS15100 ENOG4105CHV Transcription elongation factor NusA FOC86_RS15110 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC86_RS15120 ENOG4105DZP Membrane-associated zinc metalloprotease FOC86_RS15130 ENOG4105KNE Phosphatidate cytidylyltransferase FOC86_RS15175 ENOG4108HE4 integrase family FOC86_RS15185 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FOC86_RS15190 ENOG4105C79 DNA protecting protein DprA FOC86_RS15195 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FOC86_RS15210 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) FOC86_RS15235 ENOG4105VB6 UPF0109 protein FOC86_RS15255 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FOC86_RS15260 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FOC86_RS15275 ENOG4105CHR reductase FOC86_RS15280 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FOC86_RS15295 ENOG4105CB5 ATP-dependent DNA helicase recG FOC86_RS15300 ENOG4105DP4 dak2 domain fusion protein ylov FOC86_RS15305 ENOG4108ZAA Alkaline-shock protein FOC86_RS15320 ENOG4105FJ0 thiamine FOC86_RS15325 ENOG4105DJV ribulose-phosphate 3-epimerase FOC86_RS15330 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FOC86_RS15335 ENOG4105D9P serine threonine protein kinase FOC86_RS15340 ENOG4108ZF3 Phosphatase FOC86_RS15350 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FOC86_RS15360 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FOC86_RS15365 ENOG4105C25 Primosomal protein n' FOC86_RS15370 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FOC86_RS15390 ENOG4105DSJ YicC domain protein FOC86_RS15405 ENOG4105DC7 peptidase M24 FOC86_RS15490 ENOG4105C34 Pseudouridine synthase FOC86_RS15515 ENOG4105DBK s4 domain protein FOC86_RS15520 ENOG41067XK integral membrane protein FOC86_RS15530 ENOG4105DFA alanine racemase domain protein FOC86_RS15535 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FOC86_RS15540 ENOG4105WR5 sporulation protein, YlmC YmxH family FOC86_RS15550 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_RS15560 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FOC86_RS15565 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FOC86_RS15570 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) FOC86_RS15585 ENOG4105CNI cell division protein FtsW FOC86_RS15600 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FOC86_RS15605 ENOG4105CJN penicillin-binding protein FOC86_RS15610 ENOG4105CJN penicillin-binding protein FOC86_RS15615 ENOG41068DC Essential cell division protein (By similarity) FOC86_RS15650 ENOG4105KNH Nucleic acid-binding protein FOC86_RS15660 ENOG41063PX domain protein FOC86_RS15665 ENOG4105D78 K07001 NTE family protein FOC86_RS15670 ENOG4105H20 Sporulation integral membrane protein YlbJ FOC86_RS15680 ENOG4106H78 methyltransferase FOC86_RS15700 ENOG4107TB6 phosphoglycerate mutase FOC86_RS15715 ENOG4106UY4 Inherit from COG: Scp-like extracellular FOC86_RS15765 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) FOC86_RS15770 ENOG4105CNI cell division protein FtsW FOC86_RS15790 ENOG4108IAB Phoh family FOC86_RS15810 ENOG4105QA2 FOC86_RS15815 ENOG4105CI3 gtp-binding protein typa FOC86_RS15825 ENOG4105ECY inositol monophosphatase FOC86_RS15845 ENOG4105CXN decarboxylase FOC86_RS15895 ENOG4105CPP Dehydrogenase, E1 component FOC86_RS15910 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FOC86_RS15915 ENOG4108X4Q Hydrolase FOC86_RS15925 ENOG4105CN5 Metallo-Beta-Lactamase FOC86_RS15930 ENOG4107ZYR domain protein FOC86_RS15965 ENOG4108XRC Protein of unknown function (DUF458) FOC86_RS15975 ENOG4107IN1 Protein of unknown function (DUF1797) FOC86_RS15990 ENOG4105EPM Diguanylate phosphodiesterase FOC86_RS15995 ENOG4105K6S Short-chain dehydrogenase reductase Sdr FOC86_RS16010 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FOC86_RS16020 ENOG4105UIN FOC86_RS16075 ENOG4108HGU Histidine kinase FOC86_RS16085 ENOG4105CHM Aminotransferase FOC86_RS16090 ENOG4105FKQ transcriptional regulator FOC86_RS16095 ENOG4105EG2 ABC transporter, permease FOC86_RS16105 ENOG4107FKK extracellular solute-binding protein family 1 FOC86_RS16115 ENOG4105CG3 alpha amylase, catalytic region FOC86_RS16165 ENOG4105CHU acetyl-coa acetyltransferase FOC86_RS16200 ENOG4105K7K Transcriptional regulator FOC86_RS16205 ENOG4105DTD Dehydrogenase FOC86_RS16225 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FOC86_RS16265 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOC86_RS16270 ENOG4106TD9 Diguanylate cyclase FOC86_RS16290 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FOC86_RS16305 ENOG4105CID antiterminator FOC86_RS16325 ENOG4105CE4 GlcNAc 6-P deacetylase FOC86_RS16360 ENOG4107ZE5 PPIases accelerate the folding of proteins FOC86_RS16365 ENOG4105PTM secreted protein FOC86_RS16370 ENOG4105J7I hydrolase FOC86_RS16380 ENOG4105G6R Stage v sporulation protein ae FOC86_RS16390 ENOG4105CZ3 stage V sporulation protein ad FOC86_RS16395 ENOG41090VF Stage v sporulation protein ac FOC86_RS16415 ENOG4105C8J )-transporter FOC86_RS16420 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_RS16430 ENOG41082AN stage II sporulation protein FOC86_RS16435 ENOG4105DZ1 carboxypeptidase FOC86_RS16440 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC86_RS16445 ENOG4105DVE abc transporter atp-binding protein FOC86_RS16480 ENOG4105D7N magnesium and cobalt transport protein CorA FOC86_RS16505 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC86_RS16515 ENOG4105I3K Ferric uptake regulator, Fur family FOC86_RS16520 ENOG4105MZ9 stage II sporulation protein m FOC86_RS16545 ENOG4105CPC Aldo Keto reductase FOC86_RS16555 ENOG4105RHY Pfam:UPF0157 FOC86_RS16575 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FOC86_RS16585 ENOG4105ETE Transcriptional regulator (LacI family FOC86_RS16590 ENOG4108YM7 Gcn5-related n-acetyltransferase FOC86_RS16610 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FOC86_RS16615 ENOG4108R6K riboflavin synthase, subunit alpha FOC86_RS16640 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC86_RS16645 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC86_RS16660 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC86_RS16670 ENOG4105DFD Na H antiporter FOC86_RS16675 ENOG4105CGH 5'-nucleotidase FOC86_RS16765 ENOG4108IXY short-chain dehydrogenase reductase FOC86_RS16770 ENOG41069FQ Metallo-beta-lactamase superfamily FOC86_RS16775 ENOG4105II7 pyrroline-5-carboxylate reductase FOC86_RS16780 ENOG4105EJQ L-serine dehydratase FOC86_RS16805 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC86_RS16815 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FOC86_RS16820 ENOG4105D9U N-acetyltransferase FOC86_RS16835 ENOG4108VZI ErfK ybiS ycfS ynhG family protein FOC86_RS16840 ENOG4108QEG Membrane FOC86_RS16845 ENOG4105CDA abc transporter atp-binding protein FOC86_RS16850 ENOG4105E5Q amino acid AbC transporter FOC86_RS16855 ENOG4108HW3 (ABC) transporter FOC86_RS16865 ENOG4105G7B Protein of unknown function (DUF2992) FOC86_RS16870 ENOG4105E09 nadh pyrophosphatase FOC86_RS16880 ENOG4105C7S Dehydrogenase FOC86_RS16885 ENOG4105CPP Dehydrogenase, E1 component FOC86_RS16905 ENOG4107RDP Dehydrogenase FOC86_RS16915 ENOG4108JUB Transcriptional regulator FOC86_RS16925 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC86_RS16940 ENOG4107QQR Sporulation FOC86_RS16945 ENOG4105S1Z Stage IV sporulation protein B FOC86_RS16950 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FOC86_RS16960 ENOG4105DX0 Hemolysin A FOC86_RS16970 ENOG4105CTB Polyprenyl synthetase FOC86_RS16995 ENOG4108ZSR alkaline shock protein FOC86_RS17000 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC86_RS17025 ENOG410644B Stage III sporulation protein af FOC86_RS17035 ENOG4105KQ4 Stage iii sporulation protein ad FOC86_RS17040 ENOG4108CQH stage III sporulation protein AC FOC86_RS17045 ENOG4105KR5 Stage iii sporulation protein FOC86_RS17050 ENOG4105CD2 stage iii sporulation protein aa FOC86_RS17075 ENOG4105DC7 peptidase M24 FOC86_RS17090 ENOG4105CBJ Metal-dependent enzyme FOC86_RS17100 ENOG4107YBY Hydrolase FOC86_RS17135 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) FOC86_RS17140 ENOG4105WZW rhodanese family FOC86_RS17160 ENOG41080TC multidrug resistance protein FOC86_RS17200 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC86_RS17230 ENOG4105C0D helicase FOC86_RS17350 ENOG4105C3R Methionine synthase FOC86_RS17360 ENOG4105C28 cystathionine FOC86_RS17365 ENOG4105C28 cystathionine FOC86_RS17385 ENOG4105C5X domain protein FOC86_RS17395 ENOG4105DKQ ROK family FOC86_RS17405 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FOC86_RS17420 ENOG4108UTW Plays a role in the regulation of phosphate uptake FOC86_RS17430 ENOG4105E2Z phosphate ABC transporter (Permease FOC86_RS17435 ENOG4105C8U phosphate abc transporter FOC86_RS17440 ENOG4105PWN phosphate abc transporter FOC86_RS17450 ENOG4107RF6 penicillin-binding protein FOC86_RS17460 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC86_RS17485 ENOG4105N80 Ferric uptake regulator, Fur family FOC86_RS17495 ENOG4105FDK ABC transporter FOC86_RS17500 ENOG4108JYZ YitT family FOC86_RS17505 ENOG41069ZM Protein of unknown function (DUF2624) FOC86_RS17530 ENOG4105EGD dinuclear metal center protein, YbgI family FOC86_RS17545 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_RS17550 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FOC86_RS17580 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FOC86_RS17585 ENOG4105KG3 cytidine deaminase FOC86_RS17590 ENOG4107YR5 Diacylglycerol kinase FOC86_RS17600 ENOG4105CTJ Metal Dependent Phosphohydrolase FOC86_RS17605 ENOG4105C9A Phoh family FOC86_RS17615 ENOG41068P3 sporulation protein YqfC FOC86_RS17620 ENOG4105KTH gatB Yqey FOC86_RS17630 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FOC86_RS17635 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FOC86_RS17665 ENOG4105CSA Coproporphyrinogen iii oxidase FOC86_RS17670 ENOG4105KVH Transcriptional regulator FOC86_RS17695 ENOG4105TQK DNA polymerase iii, delta' subunit FOC86_RS17705 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FOC86_RS17710 ENOG4108UK2 deaminase FOC86_RS17715 ENOG4105KQC Competence protein FOC86_RS17725 ENOG4105DXX methyltransferase FOC86_RS17735 ENOG4108WF2 Metal Dependent Phosphohydrolase FOC86_RS17745 ENOG410812S Rna-binding protein FOC86_RS17755 ENOG4105CQW ribosome biogenesis GTPase YqeH FOC86_RS17760 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase FOC86_RS17775 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_RS17805 ENOG4108TVJ Nitroreductase FOC86_RS17820 ENOG4105G6Z alkaline phosphatase FOC86_RS17830 ENOG4108MUZ hydrolase FOC86_RS17865 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FOC86_RS17870 ENOG4105MIR Phenylalanine 4-monooxygenase FOC86_RS17880 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FOC86_RS17920 ENOG4105S6R Iron-hydroxamate transporter permease subunit FOC86_RS17925 ENOG4108V5C ABC transporter FOC86_RS17935 ENOG4105C0A alcohol dehydrogenase FOC86_RS17940 ENOG4105C28 cystathionine FOC86_RS17970 ENOG4107XRG penicillin-binding protein FOC86_RS17985 ENOG4105CFP Peptidase U32 FOC86_RS17990 ENOG4105XYU peptidase (U32 family) FOC86_RS18000 ENOG4105HHA aminodeoxychorismate lyase FOC86_RS18030 ENOG4105C02 permease FOC86_RS18045 ENOG41060CR FOC86_RS18050 ENOG4105C7H Helicase, RecD TraA family FOC86_RS18065 ENOG4105C3J Cysteine desulfurase FOC86_RS18075 ENOG4105D1H recombination factor protein RarA FOC86_RS18080 ENOG4108VCI transcription factor, rsfa family FOC86_RS18085 ENOG4105CUZ uba thif-type nad fad binding protein FOC86_RS18110 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FOC86_RS18120 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FOC86_RS18125 ENOG41076HS cation diffusion facilitator family transporter FOC86_RS18130 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FOC86_RS18140 ENOG4105CKP Polysaccharide Biosynthesis Protein FOC86_RS18145 ENOG4108QG2 Membrane FOC86_RS18155 ENOG4105VIE preprotein translocase, subunit YajC FOC86_RS18170 ENOG41061AI Protein of unknown function (DUF2905) FOC86_RS18185 ENOG4108HUF Transporter FOC86_RS18195 ENOG4108IPJ Membrane FOC86_RS18200 ENOG41082BM Transcriptional regulator, arsr family FOC86_RS18225 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FOC86_RS18230 ENOG4108IYU L-aspartate oxidase FOC86_RS18245 ENOG4108RPX mosc domain containing protein FOC86_RS18250 ENOG4105CQC Prephenate dehydratase FOC86_RS18270 ENOG4105EWM Histidine kinase FOC86_RS18295 ENOG4105X36 (ribosomal) protein FOC86_RS18305 ENOG4105C03 ribonuclease FOC86_RS18320 ENOG4107QMS site-determining protein FOC86_RS18340 ENOG4105DFF Rod shape-determining protein mreb FOC86_RS18360 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FOC86_RS18375 ENOG41068KH stage VI sporulation protein D FOC86_RS18385 ENOG4105D52 delta-aminolevulinic acid dehydratase FOC86_RS18410 ENOG4105K56 Transcriptional regulator FOC86_RS18430 ENOG4108IUQ atp-dependent protease FOC86_RS18460 ENOG4108QCI YvbH-like oligomerisation region FOC86_RS18490 ENOG4105M59 Phosphodiesterase, mj0936 family FOC86_RS18505 ENOG4108XJQ germination protein FOC86_RS18515 ENOG4108PCX Major Facilitator FOC86_RS18525 ENOG4105KBX Transcriptional regulator, TetR family FOC86_RS18540 ENOG4105PFC Transcriptional regulator FOC86_RS18555 ENOG4105DZC cytosine deaminase FOC86_RS18560 ENOG4105DZC cytosine deaminase FOC86_RS18565 ENOG4105DEF Extracellular solute-binding protein, family 5 FOC86_RS18570 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC86_RS18585 ENOG4108JQ7 (ABC) transporter FOC86_RS18590 ENOG4108HRK Histidine kinase FOC86_RS18595 ENOG4105DY9 regulatoR FOC86_RS18605 ENOG41067S9 phage shock protein C, PspC FOC86_RS18610 ENOG4108JCI Transcriptional regulator FOC86_RS18620 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FOC86_RS18625 ENOG4108Z40 Transcriptional regulator FOC86_RS18630 ENOG4105RHA ABC transporter, permease FOC86_RS18635 ENOG4108IUX (ABC) transporter FOC86_RS18640 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family FOC86_RS18645 ENOG4105ER2 Ompa motb domain protein FOC86_RS18650 ENOG4105E14 MotA TolQ exbB proton channel FOC86_RS18655 ENOG4108VXD carboxy-peptidase FOC86_RS18665 ENOG4105E33 succinate dehydrogenase FOC86_RS18675 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit FOC86_RS18690 ENOG4105K63 Thioredoxin FOC86_RS18695 ENOG4105C10 Electron transfer flavoprotein FOC86_RS18700 ENOG4105BZJ Electron transfer flavoprotein FOC86_RS18705 ENOG41060WC Enoyl-CoA hydratase FOC86_RS18710 ENOG4107Z3H Transcriptional regulator, TetR family FOC86_RS18715 ENOG4105CEY Amp-dependent synthetase and ligase FOC86_RS18725 ENOG4105J76 Periplasmic binding protein FOC86_RS18730 ENOG4105S6R Iron-hydroxamate transporter permease subunit FOC86_RS18770 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_RS18785 ENOG4105DR4 Methyltransferase FOC86_RS18800 ENOG4105KFN sortase, SrtB family FOC86_RS18805 ENOG4105E0A ABC, transporter FOC86_RS18820 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) FOC86_RS18825 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) FOC86_RS18835 ENOG4105FE9 pseudouridine synthase FOC86_RS18845 ENOG4105DCG PHP domain protein FOC86_RS18895 ENOG4108RWN rrna methyltransferase FOC86_RS18915 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC86_RS18920 ENOG4105CW7 secretion protein, HlyD family FOC86_RS18925 ENOG4108JGH Tetr family transcriptional regulator FOC86_RS18930 ENOG4105CN9 Peptidase m42 family protein FOC86_RS18955 ENOG4105C22 threonyL-tRNA synthetase FOC86_RS18960 ENOG4108TDW sporulation protein YtxC FOC86_RS18985 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FOC86_RS19005 ENOG4105C2M dna polymerase I FOC86_RS19010 ENOG4105BZU Histidine kinase FOC86_RS19015 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_RS19030 ENOG4108HMX isocitrate dehydrogenase (NADP) FOC86_RS19035 ENOG4105BZN citrate synthase FOC86_RS19045 ENOG4108REF Sporulation integral membrane protein ytvi FOC86_RS19050 ENOG4105FS0 cytoplasmic membrane protein FOC86_RS19075 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC86_RS19080 ENOG4105C6K Malic enzyme FOC86_RS19085 ENOG4105C0B DNA polymerase III (alpha subunit) FOC86_RS19090 ENOG4105VV2 FOC86_RS19100 ENOG4105SFS phosphoesterase RecJ domain protein FOC86_RS19140 ENOG4105DC7 peptidase M24 FOC86_RS19185 ENOG4105Z7P Acetyltransferase (GNAT) family FOC86_RS19190 ENOG41082W1 Cupin 2, conserved barrel domain protein FOC86_RS19210 ENOG4107YZX Universal stress protein FOC86_RS19250 ENOG4108JYZ YitT family FOC86_RS19280 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FOC86_RS19285 ENOG4105KBJ sporulation protein ytfj FOC86_RS19300 ENOG4105EFZ amidohydrolase FOC86_RS19310 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC86_RS19335 ENOG4106KR7 LysR family Transcriptional regulator FOC86_RS19345 ENOG4105U5Y Transcriptional regulator FOC86_RS19355 ENOG4105C28 cystathionine FOC86_RS19395 ENOG4105F1V Acetoin utilization protein FOC86_RS19400 ENOG4105W87 Cbs domain FOC86_RS19405 ENOG4105DGU Histone deacetylase FOC86_RS19420 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_RS19430 ENOG4107SNB ankyrin repeat protein YahD FOC86_RS19435 ENOG4105EP9 oxidoreductase FOC86_RS19465 ENOG4105ETE Transcriptional regulator (LacI family FOC86_RS19485 ENOG4105C88 aminopeptidase FOC86_RS19510 ENOG4105K7K Transcriptional regulator FOC86_RS19540 ENOG4108VDD TRNA binding domain protein FOC86_RS19570 ENOG4105C8F Beta-lactamase domain protein FOC86_RS19585 ENOG4108V15 phosphotransferase enzyme family FOC86_RS19590 ENOG4108IUM Glycogen debranching enzyme FOC86_RS19600 ENOG4107QSE Dipeptidase FOC86_RS19605 ENOG4105YW5 deoR family transcriptional regulator FOC86_RS19620 ENOG4105CBX hi0933 family FOC86_RS19655 ENOG4108VJ1 Transcriptional regulator (CarD family FOC86_RS19660 ENOG4107EXU Short-chain dehydrogenase reductase Sdr FOC86_RS19680 ENOG4108ZAF Molybdopterin FOC86_RS19685 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein FOC86_RS19690 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC86_RS19700 ENOG4105D06 uba thif-type nad fad binding protein FOC86_RS19705 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC86_RS19725 ENOG41085GJ domain protein FOC86_RS19735 ENOG4105DWV Homoserine O-trans-acetylase FOC86_RS19745 ENOG4108B31 Spore germination protein FOC86_RS19775 ENOG410605W Major Facilitator FOC86_RS19780 ENOG4107S91 Sodium hydrogen exchanger FOC86_RS19785 ENOG4105NCW Trka-c domain protein FOC86_RS19800 ENOG4105C19 ABC transporter FOC86_RS19820 ENOG4105N5T Radical SAM Protein FOC86_RS19830 ENOG4105CIG ABC transporter FOC86_RS19875 ENOG4105E8V Alpha Beta Hydrolase Fold protein FOC86_RS19880 ENOG4108Z0R Transferase FOC86_RS19885 ENOG4105YVM Phosphoesterase, PA-phosphatase related FOC86_RS19890 ENOG4105BZF Glycosyl transferase (Group 1 FOC86_RS19900 ENOG4108RIR Molybdenum cofactor biosynthesis protein FOC86_RS19915 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC86_RS19960 ENOG4105EGD dinuclear metal center protein, YbgI family FOC86_RS19965 ENOG4105BZU Histidine kinase FOC86_RS19970 ENOG4105BZU Histidine kinase FOC86_RS19975 ENOG4107S9D Alpha beta hydrolase FOC86_RS19980 ENOG4107T7U Sulfatase FOC86_RS19995 ENOG4105D2X ABC transporter substrate-binding protein FOC86_RS20005 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component FOC86_RS20065 ENOG4108V2W Carbonate dehydratase FOC86_RS20070 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC86_RS20075 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC86_RS20125 ENOG41087YS Phage shock protein A FOC86_RS20155 ENOG4105BZU Histidine kinase FOC86_RS20160 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_RS20185 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC86_RS20190 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) FOC86_RS20210 ENOG4105C19 ABC transporter FOC86_RS20225 ENOG4107ZTW SNARE associated Golgi FOC86_RS20235 ENOG41063TF transcriptional regulator (AraC FOC86_RS20250 ENOG4105C19 ABC transporter FOC86_RS20255 ENOG41086D8 Transcriptional regulator FOC86_RS20325 ENOG41069H0 dihydroorotase EC 3.5.2.3 FOC86_RS20345 ENOG4105DTQ mandelate racemase muconate lactonizing FOC86_RS20355 ENOG4108IPT Naphthoate synthase FOC86_RS20360 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) FOC86_RS20370 ENOG4105E4F Isochorismate synthase FOC86_RS20375 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC86_RS20385 ENOG4105VEQ Cold shock protein FOC86_RS20445 ENOG4105JVQ RNA Polymerase FOC86_RS20540 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FOC86_RS20575 ENOG4105KT7 mgtC SapB transporter FOC86_RS20580 ENOG4107PBV potassium channel FOC86_RS20595 ENOG4105WG9 Conserved Protein FOC86_RS20605 ENOG4105CHM Aminotransferase FOC86_RS20610 ENOG4108ZB6 transcriptional regulator AsnC family FOC86_RS20615 ENOG4105C5I Dehydrogenase FOC86_RS20620 ENOG4108MUZ hydrolase FOC86_RS20630 ENOG4105C87 Aminotransferase class I and II FOC86_RS20645 ENOG4105Y38 Kinase-associated protein B FOC86_RS20655 ENOG4107R3E Citrate transporter FOC86_RS20675 ENOG4105KA0 thioesterase Superfamily protein FOC86_RS20695 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOC86_RS20715 ENOG41069ER domain protein FOC86_RS20735 ENOG4105CEP NADH dehydrogenase FOC86_RS20765 ENOG4105EWC Purine nucleoside phosphorylase FOC86_RS20775 ENOG4108YX9 iron--sulfur cluster insertion protein erpA FOC86_RS20800 ENOG4108JJA ABC, transporter FOC86_RS20805 ENOG4105C4B ABC transporter, permease FOC86_RS20810 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FOC86_RS20835 ENOG41083MR nifu domain-containing protein FOC86_RS20850 ENOG4108W5N phosphatidylglycerophosphatase a FOC86_RS20865 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC86_RS20870 ENOG4105DYS nad(p)h dehydrogenase (quinone) FOC86_RS20880 ENOG4105D4U had-superfamily hydrolase, subfamily iia FOC86_RS20895 ENOG4105CBT Fructose-1,6-bisphosphatase FOC86_RS20915 ENOG4105MMD transcriptional regulator FOC86_RS20920 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FOC86_RS20925 ENOG4107TXC Transcriptional regulator FOC86_RS20930 ENOG41090T1 Membrane FOC86_RS20955 ENOG4105FAA peptidase M23 FOC86_RS20965 ENOG4105KZD Domain of unknown function (DUF1805) FOC86_RS20970 ENOG4107R8B 5'-nucleotidase FOC86_RS20975 ENOG4105DIW FeS assembly protein SUFB FOC86_RS20980 ENOG4108UNV SUF system FeS assembly protein, NifU family FOC86_RS20985 ENOG4105C9B Cysteine desulfurase FOC86_RS20990 ENOG4105JRK feS assembly protein SufD FOC86_RS20995 ENOG4105C3K feS assembly ATPase SufC FOC86_RS21000 ENOG4105D01 (LipO)protein FOC86_RS21005 ENOG4105D01 (LipO)protein FOC86_RS21010 ENOG4108UMI ABC transporter, permease FOC86_RS21040 ENOG41080E8 Transcriptional regulator, Spx MgsR family FOC86_RS21100 ENOG4108IMY Transcriptional regulator FOC86_RS21115 ENOG4108W8B Beta-lactamase domain protein FOC86_RS21120 ENOG4105C1G acyl-Coa dehydrogenase FOC86_RS21125 ENOG4105CHU acetyl-coa acetyltransferase FOC86_RS21140 ENOG4105DZ1 carboxypeptidase FOC86_RS21160 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC86_RS21180 ENOG4108SUT Major Facilitator Superfamily FOC86_RS21185 ENOG4107R7I amino acid FOC86_RS21195 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC86_RS21205 ENOG4107AYK membrAne FOC86_RS21245 ENOG4107ZTW SNARE associated Golgi FOC86_RS21255 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FOC86_RS21260 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_RS21265 ENOG4105BZU Histidine kinase FOC86_RS21285 ENOG4105C8Q Methyl-accepting chemotaxis FOC86_RS21290 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC86_RS21295 ENOG4105VG1 fes assembly suf system protein FOC86_RS21300 ENOG4105D4Y metalloprotease FOC86_RS21320 ENOG4107S91 Sodium hydrogen exchanger FOC86_RS21325 ENOG4105NCW Trka-c domain protein FOC86_RS21335 ENOG4108RMU ferritin dps family protein FOC86_RS21350 ENOG4108URH decarboxylase FOC86_RS21370 ENOG4105D9N nucleoside FOC86_RS21375 ENOG4105D9N nucleoside FOC86_RS21385 ENOG4108RYK Nad-dependent epimerase dehydratase FOC86_RS21400 ENOG4105CV8 reductase FOC86_RS21405 ENOG4105F27 Major Facilitator FOC86_RS21410 ENOG4105KVH Transcriptional regulator FOC86_RS21445 ENOG4105C8Q Methyl-accepting chemotaxis FOC86_RS21475 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC86_RS21495 ENOG4108IPW abc transporter atp-binding protein FOC86_RS21500 ENOG4105CM4 permease protein FOC86_RS21515 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_RS21525 ENOG4105C19 ABC transporter FOC86_RS21545 ENOG4107ZTW SNARE associated Golgi FOC86_RS21555 ENOG4105DHF Membrane FOC86_RS21575 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FOC86_RS21585 ENOG4105XZU Preprotein translocase, subunit SecG FOC86_RS21590 ENOG41067MG lrgb family FOC86_RS21640 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_RS21660 ENOG41090VF Stage v sporulation protein ac FOC86_RS21665 ENOG4105CZ3 stage V sporulation protein ad FOC86_RS21680 ENOG4105H67 Protein of unknown function (DUF421) FOC86_RS21690 ENOG4105KRI phosphocarrier protein (HPr FOC86_RS21700 ENOG4105CHW UPF0052 protein FOC86_RS21710 ENOG4108Z4K mutator MutT protein FOC86_RS21720 ENOG4105C3M thioredoxin reductase FOC86_RS21730 ENOG4108S4C acetyltransferase FOC86_RS21750 ENOG41086DT Membrane protein of unknown function FOC86_RS21760 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOC86_RS21780 ENOG4107TXC Transcriptional regulator FOC86_RS21810 ENOG4105HMI Membrane FOC86_RS21815 ENOG4105DUM transcriptional regulator, lysR family FOC86_RS21825 ENOG4108WS4 fmn reductase FOC86_RS21840 ENOG4105BZ1 (ABC) transporter FOC86_RS21850 ENOG4105CN1 protease FOC86_RS21855 ENOG4105CRP Part of the ABC transporter FtsEX involved in FOC86_RS21860 ENOG4105CAK Cell division ATP-binding protein ftsE FOC86_RS21880 ENOG4105MS2 ribosomal subunit Interface protein FOC86_RS21885 ENOG4105VEQ Cold shock protein FOC86_RS21890 ENOG41081UC Inherit from COG: Competence protein FOC86_RS21900 ENOG4105K4H Nlp p60 protein FOC86_RS21905 ENOG4105KVH Transcriptional regulator FOC86_RS21915 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FOC86_RS21920 ENOG4108KGH TRANSCRIPTIONal FOC86_RS21925 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FOC86_RS21930 ENOG4105C6Y Udp-glucose 6-dehydrogenase FOC86_RS21935 ENOG4105ESV Glycosyl transferase, family 4 FOC86_RS21945 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FOC86_RS21965 ENOG4105F8D glycoside hydrolase family 4 FOC86_RS21970 ENOG4105VCP PTS System FOC86_RS21975 ENOG4105CK1 PTS System FOC86_RS21985 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) FOC86_RS22005 ENOG4105VCP PTS System FOC86_RS22015 ENOG4105VZJ PTS System FOC86_RS22030 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FOC86_RS22035 ENOG4105ECB domain protein FOC86_RS22040 ENOG4107RSM transcriptional regulator FOC86_RS22080 ENOG4105DAA L-lactate FOC86_RS22090 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) FOC86_RS22100 ENOG4105E0M Sulfatase FOC86_RS22125 ENOG4107R8N Glycosyl transferase, family 2 FOC86_RS22130 ENOG4105C94 Transporter FOC86_RS22135 ENOG41069ER domain protein FOC86_RS22160 ENOG4105KBK Zinc finger, swim domain protein FOC86_RS22165 ENOG4105C0D helicase FOC86_RS22195 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_RS22210 ENOG4107RBB ABC transporter, permease FOC86_RS22215 ENOG4105C19 ABC transporter FOC86_RS22235 ENOG4105CXY transporter FOC86_RS22250 ENOG4105BZU Histidine kinase FOC86_RS22255 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_RS22260 ENOG4105CMR udp-glucose 4-epimerase FOC86_RS22275 ENOG4105D7W serine acetyltransferase FOC86_RS22280 ENOG4107QQG Dehydrogenase FOC86_RS22290 ENOG4105CJR Integral membrane protein (MviN FOC86_RS22310 ENOG4105D3Q Sugar transferase FOC86_RS22315 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOC86_RS22320 ENOG4108RB3 Capsular polysaccharide biosynthesis protein FOC86_RS22325 ENOG4107YJ4 chain length determinant protein FOC86_RS22330 ENOG4105HTX biosynthesis protein FOC86_RS22335 ENOG4107YJ4 chain length determinant protein FOC86_RS22350 ENOG4105MT0 Sporulation transcriptional regulator spoiiid FOC86_RS22360 ENOG4105FRN stage II sporulation protein FOC86_RS22375 ENOG4105DY9 regulatoR FOC86_RS22395 ENOG4106778 Protein of unknown function (DUF1146) FOC86_RS22400 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOC86_RS22405 ENOG4105C8S subunit m FOC86_RS22410 ENOG4105D65 subunit l FOC86_RS22440 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FOC86_RS22455 ENOG4105BZU Histidine kinase FOC86_RS22505 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) FOC86_RS22510 ENOG41062M3 atp synthase FOC86_RS22540 ENOG4108YZG isomerase FOC86_RS22555 ENOG4108VGI doxx family FOC86_RS22560 ENOG4107XC4 flavin reductase domain protein, FMN-binding FOC86_RS22580 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FOC86_RS22590 ENOG4108ZXQ stage ii sporulation protein r FOC86_RS22595 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FOC86_RS22615 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FOC86_RS22620 ENOG4105CBT Fructose-1,6-bisphosphatase FOC86_RS22660 ENOG4105C1G acyl-Coa dehydrogenase FOC86_RS22665 ENOG4105C1G acyl-Coa dehydrogenase FOC86_RS22670 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FOC86_RS22680 ENOG4105DF6 Fe-S oxidoreductase FOC86_RS22695 ENOG4105BZU Histidine kinase FOC86_RS22720 ENOG4105BZU Histidine kinase FOC86_RS22725 ENOG4105KCT ABC transporter FOC86_RS22730 ENOG4108M15 ABC transporter FOC86_RS22735 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) FOC86_RS22745 ENOG4105IIU Aminopeptidase FOC86_RS22765 ENOG4105DU6 RNA polymerase FOC86_RS22775 ENOG410684U Domain of unknown function (DUF1934) FOC86_RS22795 ENOG4105CYW agmatinase FOC86_RS22805 ENOG4105DXB Major Facilitator superfamily FOC86_RS22810 ENOG4107SWG transcriptional regulator MERR family FOC86_RS22815 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC86_RS22820 ENOG4105BZ4 penicillin-binding protein FOC86_RS22825 ENOG4108XFG YwhD family FOC86_RS22830 ENOG4108Z4T Peptidase M50 FOC86_RS22835 ENOG41069HH 4-oxalocrotonate tautomerase FOC86_RS22840 ENOG4105DCI Phosphohydrolase FOC86_RS22845 ENOG4108MES Periplasmic binding protein FOC86_RS22850 ENOG4105E0A ABC, transporter FOC86_RS22855 ENOG4105EHG Permease protein FOC86_RS22860 ENOG4105DQ5 transport system permease protein FOC86_RS22870 ENOG4108VCI transcription factor, rsfa family FOC86_RS22885 ENOG4108IJ2 phosphate acetyltransferase FOC86_RS22900 ENOG4108VKI Cell wall hydrolase FOC86_RS22920 ENOG4107SVH Potassium channel protein FOC86_RS22930 ENOG410667J hydrolase FOC86_RS22935 ENOG4105VCH membrane FOC86_RS22945 ENOG4108TU7 Inherit from COG: (ABC) transporter FOC86_RS22950 ENOG4105CJ1 ABC, transporter FOC86_RS22955 ENOG41090WU lipolytic protein G-D-S-L family FOC86_RS22970 ENOG4105D6E homoserine dehydrogenase FOC86_RS22990 ENOG4108Y4K DNA-binding transcriptional activator FOC86_RS23000 ENOG4105WH1 Two component transcriptional regulator luxr family FOC86_RS23005 ENOG4105BZU Histidine kinase FOC86_RS23010 ENOG4105DWF phosphomethylpyrimidine kinase FOC86_RS23015 ENOG4105BZU Histidine kinase FOC86_RS23020 ENOG4105VCD cytoplasmic protein FOC86_RS23025 ENOG4105D22 carbon starvation protein FOC86_RS23030 ENOG4105DY9 regulatoR FOC86_RS23035 ENOG41079KZ Major Facilitator Superfamily FOC86_RS23055 ENOG4105EN6 Membrane FOC86_RS23060 ENOG4106YBV Methyl-accepting chemotaxis FOC86_RS23070 ENOG4108S4H thioesterase Superfamily protein FOC86_RS23075 ENOG4105K64 Glycosyl transferase, family 2 FOC86_RS23085 ENOG4105C5H ABC transporter FOC86_RS23105 ENOG4105CKK Glycosyl transferase, family 2 FOC86_RS23110 ENOG41067SE Tetr family transcriptional regulator FOC86_RS23120 ENOG4105E0X reductase FOC86_RS23130 ENOG4106F5Q Membrane FOC86_RS23145 ENOG4105DY9 regulatoR FOC86_RS23150 ENOG4108HRK Histidine kinase FOC86_RS23155 ENOG4107RGD Major Facilitator superfamily FOC86_RS23170 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC86_RS23180 ENOG4105IW1 AmiS UreI transporter FOC86_RS23190 ENOG4105CMR udp-glucose 4-epimerase FOC86_RS23195 ENOG4108UT2 hemolysin iii FOC86_RS23210 ENOG4105C1J atp-dependent rna helicase FOC86_RS23225 ENOG4105DPN Oligoendopeptidase f FOC86_RS23245 ENOG4105C0H protease FOC86_RS23250 ENOG4105Q2H domain protein FOC86_RS23265 ENOG4105BZU Histidine kinase FOC86_RS23270 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_RS23300 ENOG4105CDU Replicative dna helicase FOC86_RS23310 ENOG4105BZR domain protein FOC86_RS23315 ENOG4108XMW Membrane FOC86_RS23325 ENOG4108UUM single-stranded DNA-binding protein FOC86_RS23335 ENOG4105C3G gtp-binding protein FOC86_RS23340 ENOG4105VDK protein, conserved in bacteria FOC86_RS23345 ENOG4105D8X mechanosensitive ion channel FOC86_RS23350 ENOG4108ZDA Sporulation protein YyaC FOC86_RS23355 ENOG4105FA0 parb-like partition protein FOC86_RS23360 ENOG4107QJE Chromosome Partitioning Protein FOC86_RS23390 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC86_RS23410 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC86_RS23415 ENOG410848D S4 domain protein YaaA FOC86_RS23430 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC86_RS23465 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FOC86_RS23500 ENOG4105ZMH deoxynucleoside kinase FOC86_RS23510 ENOG4105GTG Isochorismatase FOC86_RS23515 ENOG4108Z6B deaminase FOC86_RS23525 ENOG4105C6E dna polymerase iii FOC86_RS23545 ENOG41067KS pro-sigma K processing FOC86_RS23580 ENOG4105CXN decarboxylase FOC86_RS23590 ENOG4105FA2 dna polymerase iii FOC86_RS23595 ENOG4105MA4 psp1 domain protein FOC86_RS23605 ENOG41060K3 Methyltransferase FOC86_RS23615 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FOC86_RS23620 ENOG4105KRN Transcriptional regulator, abrb family FOC86_RS23630 ENOG4105F8V Hydrolase, tatD family FOC86_RS23635 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) FOC86_RS23645 ENOG4105XFA sporulation peptidase YabG FOC86_RS23650 ENOG4105W42 Veg protein FOC86_RS23665 ENOG4105DFT pur operon repressor FOC86_RS23670 ENOG4105KME endoribonuclease L-psp FOC86_RS23700 ENOG4108JA2 transcriptioN-repair coupling factor FOC86_RS23705 ENOG4108M14 stage v sporulation protein t FOC86_RS23715 ENOG4108IY2 MazG family FOC86_RS23720 ENOG41082I2 s4 domain protein FOC86_RS23725 ENOG4105VYY sporulation protein yabp FOC86_RS23740 ENOG41060GV RNA binding s1 domain protein FOC86_RS23765 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC86_RS23770 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FOC86_RS23785 ENOG4105C6T cysteine synthase FOC86_RS23790 ENOG4105CRQ synthase (Component I) FOC86_RS23795 ENOG4105DDQ anthranilate synthase FOC86_RS23800 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 FOC86_RS23805 ENOG4105EEI dihydropteroate synthase FOC86_RS23810 ENOG4105KRF dihydroneopterin aldolase FOC86_RS23815 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FOC86_RS23825 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FOC86_RS23915 ENOG4108Z0C Uvrb UvrC protein FOC86_RS23930 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FOC86_RS23940 ENOG4105CTP PilT protein domain protein FOC86_RS23960 ENOG4105D7W serine acetyltransferase FOC86_RS23975 ENOG4105C2N RNA methyltransferase TrmH family group 3 FOC86_RS23980 ENOG4105M0M Tetracycline resistance protein FOC86_RS23985 ENOG4105QIV RNA polymerase FOC86_RS24000 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FOC86_RS24025 ENOG4107Y49 methyltransferase FOC86_RS24040 ENOG4105XPM ribosomal protein FOC86_RS24170 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOC86_RS24180 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC86_RS24225 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FOC86_RS24255 ENOG4105D1F ATP-binding protein FOC86_RS24270 ENOG4108NMV polysaccharide deacetylase FOC86_RS24350 ENOG4105C8B TIGR00159 family FOC86_RS24355 ENOG4107U5W ybbr family FOC86_RS24380 ENOG4108VQT Alpha beta hydrolase fold protein FOC86_RS24390 ENOG4105CMG Carbohydrate kinase FOC86_RS24400 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FOC86_RS24405 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein FOC86_RS24425 ENOG4108PSK reductase FOC86_RS24440 ENOG4105IQ5 FAD linked oxidase domain protein FOC86_RS24455 ENOG4105C2C drug resistance transporter, Bcr CflA FOC86_RS24470 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC86_RS24475 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC86_RS24480 ENOG4105C3U ABC transporter FOC86_RS24485 ENOG4108JQ7 (ABC) transporter FOC86_RS24510 ENOG4105U5Y Transcriptional regulator FOC86_RS24520 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC86_RS24525 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC86_RS24535 ENOG4105II7 pyrroline-5-carboxylate reductase FOC86_RS24540 ENOG4107XDY Nicotinamide Mononucleotide Transporter FOC86_RS24550 ENOG4105E0C molybdate abc transporter FOC86_RS24555 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FOC86_RS24560 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family FOC86_RS24590 ENOG4105F6E Acyl-transferase FOC86_RS24610 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC86_RS24620 ENOG4108RE7 deoxyribonuclease FOC86_RS24630 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) FOC86_RS24655 ENOG4105C5H ABC transporter FOC86_RS24670 ENOG4105DEF Extracellular solute-binding protein, family 5 FOC86_RS24680 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC86_RS24685 ENOG4105C3U ABC transporter FOC86_RS24690 ENOG4108JQ7 (ABC) transporter FOC86_RS24695 ENOG410667J hydrolase FOC86_RS24725 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase FOC86_RS24730 ENOG4105ERH Fumarylacetoacetate hydrolase FOC86_RS24740 ENOG4108SC4 )-transporter FOC86_RS24745 ENOG4105CPF Cell wall formation (By similarity) FOC86_RS24750 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FOC86_RS24765 ENOG4107ZXI Rhomboid family FOC86_RS24775 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein FOC86_RS24780 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC86_RS24790 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) FOC86_RS24890 ENOG4105K8N protein family UPF0079, ATPase FOC86_RS24895 ENOG41072GX Peptidase M22 Glycoprotease FOC86_RS24900 ENOG410801F ribosomal-protein-alanine acetyltransferase FOC86_RS24910 ENOG4105C5H ABC transporter FOC86_RS24925 ENOG4108TYN CAAX amino terminal protease family protein FOC86_RS24945 ENOG4105C7N Xanthine uracil vitamin C permease FOC86_RS24955 ENOG4105BZU Histidine kinase FOC86_RS24980 ENOG4107ZXU DSBA oxidoreductase FOC86_RS25050 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_RS25070 ENOG4105SX7 Transporter FOC86_RS25095 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FOC86_RS25100 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FOC86_RS25105 ENOG4105C83 adenylosuccinate lyase FOC86_RS25115 ENOG4105VR9 phosphoribosylformylglycinamidine synthase FOC86_RS25140 ENOG4108V3E phosphoribosylglycinamide formyltransferase FOC86_RS25150 ENOG4105C12 Phosphoribosylglycinamide synthetase FOC86_RS25175 ENOG4105C4R Atp-dependent dna helicase FOC86_RS25205 ENOG4108W2Y isochorismatase FOC86_RS25215 ENOG4108UMI ABC transporter, permease FOC86_RS25220 ENOG4105D01 (LipO)protein FOC86_RS25240 ENOG410834F Transcriptional regulator FOC86_RS25245 ENOG4107I77 yiaA/B two helix domain FOC86_RS25265 ENOG4105CBD Diacylglycerol kinase FOC86_RS25270 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FOC86_RS25275 ENOG4108JPW Aminotransferase FOC86_RS25285 ENOG4105C26 Dehydrogenase FOC86_RS25290 ENOG4105KPY Small multidrug resistance protein FOC86_RS25310 ENOG4105D9N nucleoside FOC86_RS25315 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FOC86_RS25325 ENOG4105BZU Histidine kinase FOC86_RS25330 ENOG4108W15 Protein of unknown function (DUF1456) FOC86_RS25350 ENOG4105DTQ mandelate racemase muconate lactonizing FOC86_RS25360 ENOG4105DFD Na H antiporter FOC86_RS25380 ENOG4105D3R alkyl hydroperoxide reductase FOC86_RS25400 ENOG4105EHG Permease protein FOC86_RS25405 ENOG4105DQ5 transport system permease protein FOC86_RS25410 ENOG4108V5C ABC transporter FOC86_RS25430 ENOG4106UIA FOC86_RS25435 ENOG4106UIA FOC86_RS25470 ENOG410756H nucleotidyltransferase FOC86_RS25490 ENOG4105E5Q amino acid AbC transporter FOC86_RS25495 ENOG4105EAB amino acid AbC transporter FOC86_RS25505 ENOG4105C8Q Methyl-accepting chemotaxis FOC86_RS25510 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC86_RS25535 ENOG4105C5B carbamate kinase FOC86_RS25555 ENOG4105CI1 PTS System FOC86_RS25585 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FOC86_RS25600 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC86_RS25620 ENOG4105C5H ABC transporter FOC86_RS25650 ENOG41062JF Transcriptional regulator FOC86_RS25670 ENOG4105DEU major facilitator superfamily FOC86_RS25700 ENOG4108N0M stress protein FOC86_RS25705 ENOG4106FN3 tellurium resistance protein FOC86_RS25710 ENOG4106FN3 tellurium resistance protein FOC86_RS25715 ENOG4107TS3 membrane protein, TerC FOC86_RS25720 ENOG4108TTB tellurium resistance protein FOC86_RS25740 ENOG4105KJF protein tyrosine phosphatase FOC86_RS25750 ENOG4107U9T Pfam:Ribonuclease_BN FOC86_RS25755 ENOG4105C59 p-type ATPase FOC86_RS25760 ENOG4108IPJ Membrane FOC86_RS25785 ENOG4107ZTW SNARE associated Golgi FOC86_RS25800 ENOG410606W general stress protein FOC86_RS25805 ENOG4105UPD Calcium Proton FOC86_RS25840 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FOC86_RS25855 ENOG4108JUB Transcriptional regulator FOC86_RS25865 ENOG4108IQI permease FOC86_RS25905 ENOG4108A04 Beta-lactamase FOC86_RS25925 ENOG4105CKK Glycosyl transferase, family 2 FOC86_RS25930 ENOG4107QQG Dehydrogenase FOC86_RS25935 ENOG4105C3I Nad-dependent epimerase dehydratase FOC86_RS25955 ENOG4105F1A Pyruvate formate-lyase FOC86_RS25975 ENOG4105CI2 imidazolone-5-propionate hydrolase FOC86_RS25980 ENOG4105ECP epimerase FOC86_RS26010 ENOG41067AE Membrane-bound metal-dependent hydrolase FOC86_RS26015 ENOG4105CEN a g-specific adenine glycosylase FOC86_RS26020 ENOG4106BXE FOC86_RS26040 ENOG4105BZ1 (ABC) transporter FOC86_RS26045 ENOG4107NBY Membrane FOC86_RS26050 ENOG4105CBC glutamate synthase FOC86_RS26060 ENOG4108IUW ABC transporter FOC86_RS26080 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC86_RS26085 ENOG4105G5W regulator Fur family FOC86_RS26200 ENOG4108JQC penicillin-binding protein 1A FOC86_RS26205 ENOG4107ZQN disulfide bond FOC86_RS26215 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FOC86_RS26225 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FOC86_RS26230 ENOG4105BZU Histidine kinase FOC86_RS26235 ENOG4105CYN Serine protein kinase FOC86_RS26255 ENOG4105C94 Transporter FOC86_RS26270 ENOG4105DZ6 Band 7 protein FOC86_RS26280 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FOC86_RS26285 ENOG4108V9W transcriptional regulatory protein FOC86_RS26290 ENOG4105D4T Citrate transporter FOC86_RS26310 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FOC86_RS26315 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC86_RS26320 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FOC86_RS26325 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FOC86_RS26330 ENOG4105BZ7 extracellular solute-binding protein family 1 FOC86_RS26335 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) FOC86_RS26340 ENOG4108STX response regulator FOC86_RS26345 ENOG4105US7 Histidine kinase FOC86_RS26370 ENOG4108MRH transcriptional regulatory protein FOC86_RS26380 ENOG4105C6K Malic enzyme FOC86_RS26390 ENOG4108UZ3 Transporter FOC86_RS26395 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC86_RS26405 ENOG4105BZU Histidine kinase FOC86_RS26410 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_RS26415 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC86_RS26420 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC86_RS26425 ENOG4108JB9 formate dehydrogenase FOC86_RS26445 ENOG4105CUB amino acid FOC86_RS26455 ENOG4105C59 p-type ATPase FOC86_RS26460 ENOG4105DAP Nicotinate phosphoribosyltransferase FOC86_RS26495 ENOG41073R8 VanW family FOC86_RS26510 ENOG4108KGH TRANSCRIPTIONal FOC86_RS26515 ENOG4105D9N nucleoside FOC86_RS26520 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FOC86_RS26525 ENOG4105C37 (CBS) domain FOC86_RS26530 ENOG4108IJ0 Aspartate ammonia-lyase FOC86_RS26535 ENOG4105DAA L-lactate FOC86_RS26550 ENOG4105DUX Transporter FOC86_RS26555 ENOG4108MES Periplasmic binding protein FOC86_RS26560 ENOG4105DQ5 transport system permease protein FOC86_RS26565 ENOG4108IHU transport system permease protein FOC86_RS26570 ENOG4105E0A ABC, transporter FOC86_RS26575 ENOG4105DMQ Methyltransferase FOC86_RS26585 ENOG4105EXW epimerase dehydratase FOC86_RS26590 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) FOC86_RS26600 ENOG4107T89 von Willebrand factor, type A FOC86_RS26605 ENOG4105GMT ATPase associated with various cellular activities aaa_5 FOC86_RS26610 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC86_RS26625 ENOG4105BZU Histidine kinase FOC86_RS26630 ENOG4105D5Q Arginine ornithine antiporter FOC86_RS26635 ENOG4107414 GntR family transcriptional regulator FOC86_RS26640 ENOG4105C5Y PTS System FOC86_RS26645 ENOG4105CG3 alpha amylase, catalytic region FOC86_RS26660 ENOG4105E1K spore germination protein FOC86_RS26670 ENOG4105CRN Aminoglycoside phosphotransferase FOC86_RS26675 ENOG4105BZG amino acid carrier protein FOC86_RS26680 ENOG4105CDA abc transporter atp-binding protein FOC86_RS26685 ENOG4105CT1 (ABC) transporter FOC86_RS26690 ENOG4105EAD ABC transporter FOC86_RS26695 ENOG4105DRP amino acid AbC transporter FOC86_RS26700 ENOG4108IQI permease FOC86_RS26725 ENOG4105D29 Helix-turn-helix type 11 domain protein FOC86_RS26730 ENOG4105NAE bifunctional deaminase-reductase domain protein FOC86_RS26735 ENOG4105BZU Histidine kinase FOC86_RS26740 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_RS26750 ENOG4105CHH sulfate transporter FOC86_RS26755 ENOG41068KF Universal stress protein FOC86_RS26765 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC86_RS26775 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC86_RS26780 ENOG4108JQ7 (ABC) transporter FOC86_RS26790 ENOG4105CXY transporter FOC86_RS26795 ENOG41067TZ transcriptional regulator, MarR family FOC86_RS26800 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC86_RS26805 ENOG4105ETE Transcriptional regulator (LacI family FOC86_RS26810 ENOG4108RVA ribokinase FOC86_RS26825 ENOG4105CNN ABC, transporter FOC86_RS26830 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FOC86_RS26900 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC86_RS26905 ENOG41069ER domain protein FOC86_RS26910 ENOG4105VZ8 Transcriptional regulator FOC86_RS26925 ENOG4105DUX Transporter FOC86_RS26945 ENOG4105C85 amino acid FOC86_RS26950 ENOG4105C7N Xanthine uracil vitamin C permease FOC86_RS26965 ENOG4105MA6 gCN5-related N-acetyltransferase FOC86_RS26990 ENOG4105BZ9 Cytochrome C oxidase, subunit I FOC86_RS26995 ENOG4105E2S oxidase) subunit II FOC86_RS27000 ENOG4108IQI permease FOC86_RS27015 ENOG4106CAD Protein of unknown function (DUF3311) FOC86_RS27020 ENOG4105E1V na solute symporter FOC86_RS27035 ENOG4108NHD germination protein FOC86_RS27040 ENOG4105CE1 Ferrous iron transport protein b FOC86_RS27045 ENOG4105CE1 Ferrous iron transport protein b FOC86_RS27050 ENOG4105CE1 Ferrous iron transport protein b FOC86_RS27055 ENOG4105CVA phosphate FOC86_RS27060 ENOG4105C8U phosphate abc transporter FOC86_RS27065 ENOG4105E2Z phosphate ABC transporter (Permease FOC86_RS27195 ENOG41080XQ Signal transduction protein with cbs domains FOC86_RS27215 ENOG4105ETU transcriptional activator (TenA FOC86_RS27225 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC86_RS27235 ENOG4108VEU Thiamine monophosphate synthase FOC86_RS27240 ENOG41080HI glycine oxidase FOC86_RS27255 ENOG4105D06 uba thif-type nad fad binding protein FOC86_RS27260 ENOG4105DWF phosphomethylpyrimidine kinase FOC86_RS27310 ENOG4108INS Transcriptional regulator FOC86_RS27335 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC86_RS27345 ENOG4105CNN ABC, transporter FOC86_RS27350 ENOG4105C2J ABC transporter FOC86_RS27360 ENOG4105C7N Xanthine uracil vitamin C permease FOC86_RS27370 ENOG4108PXI ErfK YbiS YcfS YnhG FOC86_RS27390 ENOG4105C5Y PTS System FOC86_RS27425 ENOG4108B31 Spore germination protein FOC86_RS27445 ENOG4107Y03 Nitroreductase FOC86_RS27450 ENOG4105ED1 spovr family FOC86_RS27470 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase FOC86_RS27475 ENOG4105XTG Pfam:DUF156 FOC86_RS27480 ENOG4105VFE sira family FOC86_RS27485 ENOG4107TPS domain protein FOC86_RS27490 ENOG4105VFE sira family FOC86_RS27495 ENOG41085GJ domain protein FOC86_RS27505 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase FOC86_RS27510 ENOG41087NI Sulfite exporter TauE/SafE FOC86_RS27520 ENOG4108KGH TRANSCRIPTIONal FOC86_RS27525 ENOG4105CZN Potassium uptake protein FOC86_RS27545 ENOG4105EMD TRANSCRIPTIONal FOC86_RS27550 ENOG4105VCP PTS System FOC86_RS27555 ENOG4105VZJ PTS System FOC86_RS27575 ENOG41069ER domain protein