locus-tag	class	description
FOC88_RS00095	COG5484	DNA packaging
FOC88_RS00115	COG5518	Phage portal protein
FOC88_RS00120	COG2369	cell adhesion
FOC88_RS00125	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FOC88_RS00130	COG4653	Phage capsid family
FOC88_RS00230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC88_RS00255	COG2329	Antibiotic biosynthesis monooxygenase
FOC88_RS00275	COG1192	Involved in chromosome partitioning
FOC88_RS00355	COG1396	sequence-specific DNA binding
FOC88_RS00405	COG1484	DNA-dependent DNA replication
FOC88_RS00460	COG1215	transferase activity, transferring glycosyl groups
FOC88_RS00470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC88_RS00475	COG1388	LysM domain
FOC88_RS00475	COG0791	NLP P60 protein
FOC88_RS00485	COG1368	sulfuric ester hydrolase activity
FOC88_RS00495	COG2389	metal-binding protein
FOC88_RS00505	COG1620	l-lactate permease
FOC88_RS00515	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC88_RS00520	COG1294	oxidase, subunit
FOC88_RS00525	COG1271	oxidase subunit
FOC88_RS00535	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC88_RS00540	COG0583	DNA-binding transcription factor activity
FOC88_RS00545	COG1511	domain protein
FOC88_RS00550	COG0346	lactoylglutathione lyase activity
FOC88_RS00560	COG1301	dicarboxylic acid transport
FOC88_RS00565	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC88_RS00575	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC88_RS00580	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC88_RS00585	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC88_RS00595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC88_RS00600	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC88_RS00605	COG1486	melibiose metabolic process
FOC88_RS00625	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FOC88_RS00625	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC88_RS00635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC88_RS00640	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC88_RS00645	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC88_RS00650	COG1316	TRANSCRIPTIONal
FOC88_RS00655	COG1739	Uncharacterized protein family UPF0029
FOC88_RS00660	COG1307	EDD domain protein, DegV family
FOC88_RS00665	COG1733	regulation of RNA biosynthetic process
FOC88_RS00670	COG0791	NLP P60 protein
FOC88_RS00670	COG1388	LysM domain
FOC88_RS00675	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOC88_RS00680	COG1040	competence protein
FOC88_RS00685	COG1278	Cold shock
FOC88_RS00690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC88_RS00710	COG2884	Cell division ATP-binding protein ftsE
FOC88_RS00715	COG2177	Part of the ABC transporter FtsEX involved in
FOC88_RS00720	COG0793	Belongs to the peptidase S41A family
FOC88_RS00720	COG3409	Peptidoglycan-binding domain 1 protein
FOC88_RS00725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC88_RS00730	COG1132	(ABC) transporter
FOC88_RS00745	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC88_RS00755	COG0583	DNA-binding transcription factor activity
FOC88_RS00760	COG2855	membrane
FOC88_RS00790	COG0789	Transcriptional regulator
FOC88_RS00810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC88_RS00820	COG1950	PFAM Membrane protein of
FOC88_RS00840	COG0110	maltose O-acetyltransferase activity
FOC88_RS00845	COG0457	Tetratricopeptide repeat
FOC88_RS00850	COG0492	ferredoxin-NADP+ reductase activity
FOC88_RS00860	COG1051	belongs to the nudix hydrolase family
FOC88_RS00870	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC88_RS00880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC88_RS00890	COG2323	membrane
FOC88_RS00905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC88_RS00930	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC88_RS00945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC88_RS00980	COG1346	cytolysis
FOC88_RS00985	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC88_RS00990	COG1647	Serine aminopeptidase, S33
FOC88_RS00995	COG0557	exoribonuclease II activity
FOC88_RS01055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC88_RS01085	COG0840	transmembrane signaling receptor activity
FOC88_RS01085	COG3290	protein histidine kinase activity
FOC88_RS01110	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC88_RS01115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC88_RS01120	COG1252	NADH dehydrogenase
FOC88_RS01130	COG1733	regulation of RNA biosynthetic process
FOC88_RS01135	COG2814	Major facilitator Superfamily
FOC88_RS01140	COG0656	L-ascorbic acid biosynthetic process
FOC88_RS01160	COG2910	NAD(P)H-binding
FOC88_RS01165	COG1115	amino acid carrier protein
FOC88_RS01170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC88_RS01175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC88_RS01195	COG1611	Belongs to the LOG family
FOC88_RS01210	COG0783	Belongs to the Dps family
FOC88_RS01215	COG1115	amino acid carrier protein
FOC88_RS01220	COG0490	domain, Protein
FOC88_RS01225	COG0475	glutathione-regulated potassium exporter activity
FOC88_RS01240	COG1741	Belongs to the pirin family
FOC88_RS01245	COG3227	Zinc metalloprotease (Elastase)
FOC88_RS01250	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC88_RS01255	COG0840	transmembrane signaling receptor activity
FOC88_RS01280	COG5002	protein histidine kinase activity
FOC88_RS01285	COG0745	RESPONSE REGULATOR receiver
FOC88_RS01290	COG1376	ErfK ybiS ycfS ynhG family protein
FOC88_RS01300	COG0586	Pfam SNARE associated Golgi protein
FOC88_RS01335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC88_RS01345	COG0706	membrane insertase activity
FOC88_RS01355	COG0531	amino acid
FOC88_RS01360	COG2814	Major facilitator Superfamily
FOC88_RS01380	COG0840	transmembrane signaling receptor activity
FOC88_RS01385	COG0011	TIGRFAM Protein of
FOC88_RS01400	COG1686	Belongs to the peptidase S11 family
FOC88_RS01410	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC88_RS01410	COG1024	Enoyl-CoA hydratase
FOC88_RS01415	COG0183	Belongs to the thiolase family
FOC88_RS01425	COG1960	acyl-CoA dehydrogenase activity
FOC88_RS01430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC88_RS01435	COG1309	transcriptional regulator
FOC88_RS01440	COG1396	sequence-specific DNA binding
FOC88_RS01510	COG1393	Belongs to the ArsC family
FOC88_RS01520	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC88_RS01525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC88_RS01540	COG2011	ABC-type metal ion transport system permease component
FOC88_RS01545	COG1464	Belongs to the NlpA lipoprotein family
FOC88_RS01550	COG1464	Belongs to the NlpA lipoprotein family
FOC88_RS01555	COG0396	ATPase activity
FOC88_RS01560	COG0719	Fe-S assembly protein
FOC88_RS01565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC88_RS01570	COG0822	iron-sulfur transferase activity
FOC88_RS01575	COG0719	Fe-S assembly protein
FOC88_RS01580	COG0737	Belongs to the 5'-nucleotidase family
FOC88_RS01585	COG3377	Domain of unknown function (DUF1805)
FOC88_RS01595	COG0739	heme binding
FOC88_RS01620	COG4377	Putative membrane peptidase family (DUF2324)
FOC88_RS01625	COG0789	Transcriptional regulator
FOC88_RS01635	COG4470	Protein conserved in bacteria
FOC88_RS01650	COG1494	fructose-1,6-bisphosphatase
FOC88_RS01655	COG2445	Protein of unknown function DUF86
FOC88_RS01665	COG0647	UMP catabolic process
FOC88_RS01675	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC88_RS01685	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC88_RS01690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC88_RS01700	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC88_RS01705	COG4837	Protein of unknown function (DUF1462)
FOC88_RS01725	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC88_RS01730	COG0390	transport system, permease component
FOC88_RS01745	COG1252	NADH dehydrogenase
FOC88_RS01760	COG0316	Belongs to the HesB IscA family
FOC88_RS01770	COG1683	Conserved Protein
FOC88_RS01800	COG1252	NADH dehydrogenase
FOC88_RS01820	COG3584	3D domain protein
FOC88_RS01835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC88_RS01840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC88_RS01850	COG1268	BioY protein
FOC88_RS01860	COG2050	protein possibly involved in aromatic compounds catabolism
FOC88_RS01880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC88_RS01885	COG5018	Exonuclease
FOC88_RS01905	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC88_RS01915	COG2267	carboxylic ester hydrolase activity
FOC88_RS01920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC88_RS01925	COG1522	sequence-specific DNA binding
FOC88_RS01930	COG0436	Aminotransferase
FOC88_RS01935	COG1098	S1 RNA binding domain
FOC88_RS01940	COG2155	Conserved Protein
FOC88_RS01955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC88_RS01960	COG1285	pathogenesis
FOC88_RS01995	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC88_RS02090	COG1595	DNA-templated transcription, initiation
FOC88_RS02125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC88_RS02135	COG0058	SHG alpha-glucan phosphorylase activity
FOC88_RS02155	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC88_RS02160	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC88_RS02165	COG1169	isochorismate synthase
FOC88_RS02170	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC88_RS02175	COG0596	Alpha beta hydrolase
FOC88_RS02180	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC88_RS02190	COG4948	Mandelate Racemase Muconate Lactonizing
FOC88_RS02220	COG3964	amidohydrolase
FOC88_RS02240	COG2188	Transcriptional regulator
FOC88_RS02255	COG0577	efflux transmembrane transporter activity
FOC88_RS02260	COG1136	(ABC) transporter
FOC88_RS02265	COG0577	efflux transmembrane transporter activity
FOC88_RS02270	COG0577	efflux transmembrane transporter activity
FOC88_RS02275	COG2205	protein histidine kinase activity
FOC88_RS02280	COG0745	RESPONSE REGULATOR receiver
FOC88_RS02285	COG2207	Transcriptional regulator
FOC88_RS02285	COG3708	Transcriptional regulator
FOC88_RS02290	COG1136	(ABC) transporter
FOC88_RS02295	COG0577	efflux transmembrane transporter activity
FOC88_RS02305	COG0586	Pfam SNARE associated Golgi protein
FOC88_RS02330	COG1597	lipid kinase activity
FOC88_RS02360	COG0745	RESPONSE REGULATOR receiver
FOC88_RS02365	COG5002	protein histidine kinase activity
FOC88_RS02395	COG1842	Phage shock protein A
FOC88_RS02420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC88_RS02440	COG1294	oxidase, subunit
FOC88_RS02445	COG1271	oxidase subunit
FOC88_RS02450	COG0288	reversible hydration of carbon dioxide
FOC88_RS02485	COG0494	nUDIX hydrolase
FOC88_RS02510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC88_RS02515	COG1116	anion transmembrane transporter activity
FOC88_RS02520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC88_RS02535	COG1368	sulfuric ester hydrolase activity
FOC88_RS02540	COG2267	carboxylic ester hydrolase activity
FOC88_RS02545	COG4191	Histidine kinase
FOC88_RS02550	COG5002	protein histidine kinase activity
FOC88_RS02555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC88_RS02610	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC88_RS02620	COG0438	transferase activity, transferring glycosyl groups
FOC88_RS02625	COG0671	phosphoesterase, PA-phosphatase related
FOC88_RS02630	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC88_RS02635	COG2267	carboxylic ester hydrolase activity
FOC88_RS02655	COG1794	racemase activity, acting on amino acids and derivatives
FOC88_RS02670	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC88_RS02675	COG1242	4 iron, 4 sulfur cluster binding
FOC88_RS02695	COG1136	(ABC) transporter
FOC88_RS02705	COG0582	viral genome integration into host DNA
FOC88_RS02710	COG0490	domain, Protein
FOC88_RS02715	COG0475	glutathione-regulated potassium exporter activity
FOC88_RS02720	COG2814	Major facilitator Superfamily
FOC88_RS02760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC88_RS02770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC88_RS02790	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC88_RS02795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC88_RS02805	COG0303	'Molybdopterin
FOC88_RS02810	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC88_RS02815	COG0314	molybdopterin synthase activity
FOC88_RS02840	COG1329	Transcriptional regulator
FOC88_RS02860	COG3832	glyoxalase III activity
FOC88_RS02870	COG2814	Major facilitator Superfamily
FOC88_RS02875	COG2081	HI0933 family
FOC88_RS02880	COG2244	polysaccharide biosynthetic process
FOC88_RS02885	COG1187	pseudouridine synthase activity
FOC88_RS02890	COG1349	DNA-binding transcription factor activity
FOC88_RS02895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC88_RS02905	COG1523	belongs to the glycosyl hydrolase 13 family
FOC88_RS02910	COG0510	thiamine kinase activity
FOC88_RS02925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC88_RS02935	COG1363	Peptidase, m42
FOC88_RS02940	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC88_RS02945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC88_RS02955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC88_RS02965	COG1674	ftsk spoiiie
FOC88_RS02985	COG1695	Transcriptional regulator
FOC88_RS02990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC88_RS03015	COG2309	aminopeptidase activity
FOC88_RS03025	COG3118	belongs to the thioredoxin family
FOC88_RS03030	COG4851	CamS sex pheromone cAM373 precursor
FOC88_RS03035	COG1609	Transcriptional regulator
FOC88_RS03070	COG0666	response to abiotic stimulus
FOC88_RS03080	COG0745	RESPONSE REGULATOR receiver
FOC88_RS03090	COG2267	carboxylic ester hydrolase activity
FOC88_RS03095	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOC88_RS03100	COG0517	IMP dehydrogenase activity
FOC88_RS03105	COG0454	-acetyltransferase
FOC88_RS03110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC88_RS03120	COG1595	DNA-templated transcription, initiation
FOC88_RS03155	COG1956	GAF domain-containing protein
FOC88_RS03160	COG1309	transcriptional regulator
FOC88_RS03165	COG0697	spore germination
FOC88_RS03170	COG0583	DNA-binding transcription factor activity
FOC88_RS03180	COG1104	cysteine desulfurase activity
FOC88_RS03195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC88_RS03205	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC88_RS03220	COG3874	Sporulation protein YtfJ
FOC88_RS03225	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC88_RS03230	COG0827	DNA restriction-modification system
FOC88_RS03255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC88_RS03295	COG0589	response to stress
FOC88_RS03300	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS03315	COG1476	TRANSCRIPTIONal
FOC88_RS03325	COG0662	Cupin 2, conserved barrel domain protein
FOC88_RS03370	COG0006	proline dipeptidase activity
FOC88_RS03385	COG4109	DRTGG domain
FOC88_RS03395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC88_RS03410	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC88_RS03425	COG0587	DNA-directed DNA polymerase activity
FOC88_RS03430	COG0281	malic enzyme
FOC88_RS03435	COG1725	Transcriptional regulator
FOC88_RS03460	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOC88_RS03465	COG0628	permease
FOC88_RS03475	COG0372	Belongs to the citrate synthase family
FOC88_RS03480	COG0538	isocitrate dehydrogenase activity
FOC88_RS03500	COG0745	RESPONSE REGULATOR receiver
FOC88_RS03505	COG5002	protein histidine kinase activity
FOC88_RS03510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC88_RS03510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC88_RS03520	COG1971	Probably functions as a manganese efflux pump
FOC88_RS03525	COG0237	dephospho-CoA kinase activity
FOC88_RS03530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC88_RS03535	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC88_RS03545	COG3611	Membrane attachment protein
FOC88_RS03550	COG1484	DNA-dependent DNA replication
FOC88_RS03560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC88_RS03585	COG1363	Peptidase, m42
FOC88_RS03590	COG1309	transcriptional regulator
FOC88_RS03595	COG1566	PFAM secretion protein HlyD family protein
FOC88_RS03600	COG2814	Major facilitator Superfamily
FOC88_RS03625	COG1418	mRNA catabolic process
FOC88_RS03635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC88_RS03680	COG1286	toxin biosynthetic process
FOC88_RS03685	COG1796	DNA polymerase
FOC88_RS03685	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC88_RS03695	COG1187	pseudouridine synthase activity
FOC88_RS03700	COG1114	Component of the transport system for branched-chain amino acids
FOC88_RS03705	COG5386	Cell surface protein
FOC88_RS03710	COG5386	Cell surface protein
FOC88_RS03725	COG1120	ATPase activity
FOC88_RS03730	COG4509	Sortase family
FOC88_RS03745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC88_RS03750	COG4895	conserved protein (DUF2196)
FOC88_RS03760	COG0745	RESPONSE REGULATOR receiver
FOC88_RS03765	COG2205	protein histidine kinase activity
FOC88_RS03770	COG1131	(ABC) transporter
FOC88_RS03795	COG2318	DinB family
FOC88_RS03815	COG0318	PFAM AMP-dependent synthetase and ligase
FOC88_RS03820	COG1309	transcriptional regulator
FOC88_RS03825	COG1024	Enoyl-CoA hydratase
FOC88_RS03830	COG2086	electron transfer activity
FOC88_RS03835	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC88_RS03840	COG3118	belongs to the thioredoxin family
FOC88_RS03850	COG1719	4-vinyl reductase, 4VR
FOC88_RS03855	COG2009	succinate dehydrogenase
FOC88_RS03860	COG1053	succinate dehydrogenase
FOC88_RS03865	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC88_RS03870	COG0824	Thioesterase
FOC88_RS03875	COG1876	peptidase activity
FOC88_RS03880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC88_RS03885	COG1360	Flagellar Motor Protein
FOC88_RS03890	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOC88_RS03895	COG4152	abc transporter atp-binding protein
FOC88_RS03900	COG1668	transmembrane transport
FOC88_RS03905	COG1959	2 iron, 2 sulfur cluster binding
FOC88_RS03915	COG0697	spore germination
FOC88_RS03920	COG1396	sequence-specific DNA binding
FOC88_RS03925	COG1983	PspC domain protein
FOC88_RS03945	COG3279	Response regulator of the LytR AlgR family
FOC88_RS03950	COG3275	phosphorelay sensor kinase activity
FOC88_RS03955	COG4608	Belongs to the ABC transporter superfamily
FOC88_RS03960	COG0444	Belongs to the ABC transporter superfamily
FOC88_RS03980	COG0402	S-adenosylhomocysteine deaminase activity
FOC88_RS03985	COG0402	S-adenosylhomocysteine deaminase activity
FOC88_RS03995	COG2233	PERMEase
FOC88_RS04000	COG2197	response regulator
FOC88_RS04015	COG1309	transcriptional regulator
FOC88_RS04035	COG5401	PFAM Sporulation and spore germination
FOC88_RS04050	COG0622	Phosphoesterase
FOC88_RS04100	COG0470	DNA polymerase III
FOC88_RS04100	COG1067	ATP-dependent peptidase activity
FOC88_RS04115	COG1764	response to oxidative stress
FOC88_RS04120	COG1846	Transcriptional regulator
FOC88_RS04130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC88_RS04140	COG1587	Uroporphyrinogen-III synthase
FOC88_RS04145	COG0113	porphobilinogen synthase activity
FOC88_RS04155	COG1388	LysM domain
FOC88_RS04165	COG0525	valine-tRNA ligase activity
FOC88_RS04170	COG0285	dihydrofolate synthase activity
FOC88_RS04190	COG1077	Cell shape determining protein MreB Mrl
FOC88_RS04210	COG2894	cell division
FOC88_RS04215	COG0739	heme binding
FOC88_RS04220	COG1994	Peptidase M50
FOC88_RS04225	COG1530	ribonuclease E activity
FOC88_RS04235	COG2868	ribosomal protein
FOC88_RS04245	COG3290	protein histidine kinase activity
FOC88_RS04255	COG0745	RESPONSE REGULATOR receiver
FOC88_RS04260	COG5002	protein histidine kinase activity
FOC88_RS04265	COG1136	(ABC) transporter
FOC88_RS04270	COG0577	efflux transmembrane transporter activity
FOC88_RS04275	COG0577	efflux transmembrane transporter activity
FOC88_RS04280	COG0077	Prephenate dehydratase
FOC88_RS04285	COG2258	MOSC domain
FOC88_RS04290	COG1827	regulation of RNA biosynthetic process
FOC88_RS04295	COG1104	cysteine desulfurase activity
FOC88_RS04300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC88_RS04305	COG0157	Belongs to the NadC ModD family
FOC88_RS04330	COG0640	Transcriptional regulator
FOC88_RS04335	COG0697	spore germination
FOC88_RS04345	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOC88_RS04375	COG1862	Preprotein translocase
FOC88_RS04385	COG2323	membrane
FOC88_RS04390	COG2244	polysaccharide biosynthetic process
FOC88_RS04400	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC88_RS04400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC88_RS04405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC88_RS04410	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC88_RS04410	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC88_RS04420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC88_RS04445	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC88_RS04455	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC88_RS04460	COG1959	2 iron, 2 sulfur cluster binding
FOC88_RS04465	COG1104	cysteine desulfurase activity
FOC88_RS04480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC88_RS04500	COG0628	permease
FOC88_RS04530	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC88_RS04535	COG4122	O-methyltransferase activity
FOC88_RS04560	COG0768	penicillin binding
FOC88_RS04585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC88_RS04590	COG0626	cystathionine gamma-synthase activity
FOC88_RS04595	COG1454	alcohol dehydrogenase
FOC88_RS04595	COG1012	belongs to the aldehyde dehydrogenase family
FOC88_RS04605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC88_RS04645	COG2259	Doxx family
FOC88_RS04650	COG2514	catechol 2,3-dioxygenase activity
FOC88_RS04660	COG3186	Phenylalanine-4-hydroxylase
FOC88_RS04665	COG1404	Belongs to the peptidase S8 family
FOC88_RS04700	COG2267	carboxylic ester hydrolase activity
FOC88_RS04710	COG1785	Belongs to the alkaline phosphatase family
FOC88_RS04720	COG2357	RelA SpoT domain protein
FOC88_RS04725	COG0778	Nitroreductase
FOC88_RS04735	COG1595	DNA-templated transcription, initiation
FOC88_RS04760	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOC88_RS04765	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC88_RS04775	COG1534	Rna-binding protein
FOC88_RS04785	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOC88_RS04790	COG0799	negative regulation of ribosome biogenesis
FOC88_RS04795	COG2226	methyltransferase
FOC88_RS04800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC88_RS04805	COG1596	polysaccharide export
FOC88_RS04805	COG1555	photosystem II stabilization
FOC88_RS04810	COG2131	deaminase
FOC88_RS04815	COG2333	competence protein COMEC
FOC88_RS04815	COG0658	competence protein
FOC88_RS04825	COG1466	dna polymerase III delta subunit
FOC88_RS04850	COG1733	regulation of RNA biosynthetic process
FOC88_RS04855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC88_RS04885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC88_RS04890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC88_RS04895	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOC88_RS04900	COG1610	YqeY-like protein
FOC88_RS04915	COG1702	phosphate starvation-inducible protein PhoH
FOC88_RS04920	COG1480	7TM receptor with intracellular HD hydrolase
FOC88_RS04930	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC88_RS04935	COG0295	cytidine deaminase activity
FOC88_RS04940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC88_RS04955	COG0517	IMP dehydrogenase activity
FOC88_RS04970	COG0358	DNA primase activity
FOC88_RS04975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC88_RS04980	COG2010	Cytochrome c
FOC88_RS04985	COG2384	SAM-dependent methyltransferase
FOC88_RS04990	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC88_RS05020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC88_RS05025	COG1121	(ABC) transporter
FOC88_RS05030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC88_RS05035	COG0735	belongs to the Fur family
FOC88_RS05060	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC88_RS05065	COG0477	Major facilitator Superfamily
FOC88_RS05075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC88_RS05080	COG0573	inorganic phosphate transmembrane transporter activity
FOC88_RS05085	COG0581	inorganic phosphate transmembrane transporter activity
FOC88_RS05095	COG0704	Plays a role in the regulation of phosphate uptake
FOC88_RS05100	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC88_RS05105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC88_RS05110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC88_RS05115	COG4483	Protein conserved in bacteria
FOC88_RS05120	COG1940	carbohydrate kinase activity
FOC88_RS05130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC88_RS05150	COG0626	cystathionine gamma-synthase activity
FOC88_RS05155	COG0626	cystathionine gamma-synthase activity
FOC88_RS05160	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC88_RS05160	COG0646	methionine synthase
FOC88_RS05165	COG1410	methionine synthase
FOC88_RS05165	COG0646	methionine synthase
FOC88_RS05170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC88_RS05215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC88_RS05220	COG1459	type II secretion system
FOC88_RS05230	COG4970	Tfp pilus assembly protein FimT
FOC88_RS05285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC88_RS05315	COG1725	Transcriptional regulator
FOC88_RS05355	COG2076	Multidrug Resistance protein
FOC88_RS05360	COG2076	Multidrug Resistance protein
FOC88_RS05370	COG1609	Transcriptional regulator
FOC88_RS05375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC88_RS05380	COG0095	Lipoate-protein ligase
FOC88_RS05415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC88_RS05425	COG3872	metal-dependent enzyme
FOC88_RS05440	COG0006	proline dipeptidase activity
FOC88_RS05465	COG3854	ATPases associated with a variety of cellular activities
FOC88_RS05510	COG0511	ligase activity, forming carbon-carbon bonds
FOC88_RS05515	COG0439	Biotin carboxylase
FOC88_RS05520	COG1302	Protein conserved in bacteria
FOC88_RS05545	COG0142	geranyltranstransferase activity
FOC88_RS05555	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOC88_RS05565	COG0497	DNA recombination
FOC88_RS05570	COG0750	zinc metalloprotease
FOC88_RS05575	COG0745	RESPONSE REGULATOR receiver
FOC88_RS05585	COG3093	addiction module antidote protein HigA
FOC88_RS05590	COG0584	glycerophosphoryl diester phosphodiesterase
FOC88_RS05600	COG3290	protein histidine kinase activity
FOC88_RS05600	COG3829	transcription factor binding
FOC88_RS05605	COG0280	phosphate acetyltransferase
FOC88_RS05620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC88_RS05625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC88_RS05630	COG0022	dehydrogenase e1 component
FOC88_RS05635	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC88_RS05640	COG0772	Belongs to the SEDS family
FOC88_RS05645	COG2816	NAD+ diphosphatase activity
FOC88_RS05660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC88_RS05665	COG0765	amino acid transport
FOC88_RS05670	COG1126	abc transporter atp-binding protein
FOC88_RS05675	COG4129	membrane
FOC88_RS05680	COG1376	ErfK ybiS ycfS ynhG family protein
FOC88_RS05695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC88_RS05700	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC88_RS05710	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC88_RS05730	COG1760	l-serine dehydratase
FOC88_RS05735	COG1760	l-serine dehydratase
FOC88_RS05740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC88_RS05745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC88_RS05750	COG0300	oxidoreductase activity
FOC88_RS05765	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOC88_RS05775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC88_RS05795	COG1522	sequence-specific DNA binding
FOC88_RS05805	COG0737	Belongs to the 5'-nucleotidase family
FOC88_RS05820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC88_RS05835	COG1073	alpha beta
FOC88_RS05835	COG2226	methyltransferase
FOC88_RS05840	COG4106	trans-aconitate 2-methyltransferase activity
FOC88_RS05865	COG0307	riboflavin synthase, alpha
FOC88_RS05870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC88_RS05870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC88_RS05885	COG1073	alpha beta
FOC88_RS05890	COG0456	acetyltransferase
FOC88_RS05895	COG1609	Transcriptional regulator
FOC88_RS05900	COG2056	Na+-H+ antiporter family
FOC88_RS05905	COG0596	Alpha beta hydrolase
FOC88_RS05915	COG1525	nuclease
FOC88_RS05915	COG4085	toxin activity
FOC88_RS05915	COG0737	Belongs to the 5'-nucleotidase family
FOC88_RS05925	COG0456	acetyltransferase
FOC88_RS05925	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC88_RS05930	COG0656	L-ascorbic acid biosynthetic process
FOC88_RS05935	COG0667	Aldo Keto reductase
FOC88_RS05955	COG1300	Membrane
FOC88_RS05960	COG0735	belongs to the Fur family
FOC88_RS05970	COG4974	Belongs to the 'phage' integrase family
FOC88_RS05995	COG0598	Magnesium transport protein CorA
FOC88_RS06010	COG1846	Transcriptional regulator
FOC88_RS06030	COG1131	(ABC) transporter
FOC88_RS06035	COG1725	Transcriptional regulator
FOC88_RS06040	COG1686	Belongs to the peptidase S11 family
FOC88_RS06060	COG0733	neurotransmitter:sodium symporter activity
FOC88_RS06085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC88_RS06100	COG0697	spore germination
FOC88_RS06105	COG0561	phosphatase activity
FOC88_RS06110	COG4086	secreted protein
FOC88_RS06115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC88_RS06120	COG0456	acetyltransferase
FOC88_RS06125	COG1547	Domain of unknown function (DUF309)
FOC88_RS06150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC88_RS06160	COG2188	Transcriptional regulator
FOC88_RS06170	COG3711	transcriptional antiterminator
FOC88_RS06175	COG2190	(PTS) system
FOC88_RS06175	COG1263	PTS System
FOC88_RS06175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC88_RS06200	COG0778	Nitroreductase
FOC88_RS06205	COG3706	GGDEF domain
FOC88_RS06210	COG2084	Dehydrogenase
FOC88_RS06245	COG0436	Aminotransferase
FOC88_RS06250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC88_RS06260	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FOC88_RS06270	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS06275	COG1695	Transcriptional regulator
FOC88_RS06310	COG0183	Belongs to the thiolase family
FOC88_RS06350	COG3842	ATPase activity
FOC88_RS06355	COG0366	Alpha amylase catalytic
FOC88_RS06365	COG2182	Extracellular solute-binding protein
FOC88_RS06370	COG1175	transmembrane transport
FOC88_RS06375	COG3833	ABC-type maltose transport systems, permease component
FOC88_RS06380	COG1609	Transcriptional regulator
FOC88_RS06385	COG0436	Aminotransferase
FOC88_RS06395	COG2205	protein histidine kinase activity
FOC88_RS06405	COG3209	COG3209 Rhs family protein
FOC88_RS06425	COG2814	Major facilitator Superfamily
FOC88_RS06460	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC88_RS06470	COG1408	metallophosphoesterase
FOC88_RS06475	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS06480	COG2200	EAL domain
FOC88_RS06495	COG4703	Protein of unknown function (DUF1797)
FOC88_RS06505	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOC88_RS06515	COG0517	IMP dehydrogenase activity
FOC88_RS06520	COG0583	DNA-binding transcription factor activity
FOC88_RS06540	COG0569	domain protein
FOC88_RS06545	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC88_RS06555	COG0561	phosphatase activity
FOC88_RS06560	COG0242	peptide deformylase activity
FOC88_RS06570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC88_RS06575	COG0022	dehydrogenase e1 component
FOC88_RS06625	COG1982	Orn Lys Arg decarboxylase major
FOC88_RS06645	COG0483	inositol monophosphate 1-phosphatase activity
FOC88_RS06670	COG4896	Protein conserved in bacteria
FOC88_RS06680	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC88_RS06685	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC88_RS06695	COG0772	Belongs to the SEDS family
FOC88_RS06700	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOC88_RS06735	COG3336	cytochrome c oxidase
FOC88_RS06750	COG2340	Cysteine-rich secretory protein family
FOC88_RS06765	COG0406	alpha-ribazole phosphatase activity
FOC88_RS06770	COG3679	Belongs to the UPF0342 family
FOC88_RS06785	COG0742	ribosomal rna small subunit methyltransferase
FOC88_RS06795	COG3314	Sporulation integral membrane protein YlbJ
FOC88_RS06800	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC88_RS06805	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOC88_RS06815	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC88_RS06820	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOC88_RS06835	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC88_RS06850	COG4839	cell division protein FtsL
FOC88_RS06860	COG0768	penicillin binding
FOC88_RS06865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC88_RS06880	COG0772	Belongs to the SEDS family
FOC88_RS06890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC88_RS06895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC88_RS06900	COG0849	cell division
FOC88_RS06905	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC88_RS06915	COG1191	sigma factor activity
FOC88_RS06920	COG1191	sigma factor activity
FOC88_RS06925	COG1873	PFAM PRC-barrel domain
FOC88_RS06935	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC88_RS06945	COG0762	integral membrane protein
FOC88_RS06950	COG2302	S4 RNA-binding domain
FOC88_RS06955	COG3599	regulation of cell shape
FOC88_RS06975	COG0564	pseudouridine synthase activity
FOC88_RS07035	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC88_RS07055	COG0006	proline dipeptidase activity
FOC88_RS07065	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC88_RS07070	COG1561	YicC-like family, N-terminal region
FOC88_RS07090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC88_RS07095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC88_RS07100	COG0242	peptide deformylase activity
FOC88_RS07110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC88_RS07110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC88_RS07120	COG0631	protein serine/threonine phosphatase activity
FOC88_RS07125	COG2815	serine threonine protein kinase
FOC88_RS07125	COG0515	serine threonine protein kinase
FOC88_RS07130	COG1162	GTPase activity
FOC88_RS07135	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC88_RS07140	COG1564	THIamine pyrophosphokinase
FOC88_RS07155	COG1302	Protein conserved in bacteria
FOC88_RS07160	COG1461	Dihydroxyacetone kinase
FOC88_RS07165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC88_RS07180	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC88_RS07185	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS07190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC88_RS07200	COG1196	nuclear chromosome segregation
FOC88_RS07205	COG0552	protein localization to endoplasmic reticulum
FOC88_RS07215	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC88_RS07225	COG1837	Belongs to the UPF0109 family
FOC88_RS07265	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC88_RS07270	COG0758	DNA mediated transformation
FOC88_RS07275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC88_RS07285	COG4974	Belongs to the 'phage' integrase family
FOC88_RS07315	COG0528	UMP kinase activity
FOC88_RS07330	COG4589	Belongs to the CDS family
FOC88_RS07340	COG0750	zinc metalloprotease
FOC88_RS07360	COG0195	Participates in both transcription termination and antitermination
FOC88_RS07365	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOC88_RS07370	COG1358	cellular component organization or biogenesis
FOC88_RS07380	COG1550	Protein conserved in bacteria
FOC88_RS07390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC88_RS07395	COG0196	riboflavin kinase activity
FOC88_RS07410	COG0726	polysaccharide deacetylase
FOC88_RS07415	COG0612	Peptidase, M16
FOC88_RS07420	COG1873	PFAM PRC-barrel domain
FOC88_RS07425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC88_RS07430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC88_RS07435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC88_RS07440	COG0527	aspartate kinase activity
FOC88_RS07450	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC88_RS07455	COG0740	serine-type endopeptidase activity
FOC88_RS07465	COG1674	ftsk spoiiie
FOC88_RS07470	COG2188	Transcriptional regulator
FOC88_RS07495	COG0612	Peptidase, M16
FOC88_RS07500	COG0612	Peptidase, M16
FOC88_RS07505	COG0300	oxidoreductase activity
FOC88_RS07520	COG1426	Protein conserved in bacteria
FOC88_RS07525	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC88_RS07550	COG1692	metallophosphoesterase
FOC88_RS07555	COG2359	stage V sporulation protein S
FOC88_RS07565	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC88_RS07565	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC88_RS07570	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC88_RS07580	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOC88_RS07600	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOC88_RS07610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC88_RS07615	COG1368	sulfuric ester hydrolase activity
FOC88_RS07620	COG0562	UDP-galactopyranose mutase
FOC88_RS07625	COG3773	Cell wall hydrolase
FOC88_RS07630	COG1404	Belongs to the peptidase S8 family
FOC88_RS07650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC88_RS07655	COG0596	Alpha beta hydrolase
FOC88_RS07655	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC88_RS07660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC88_RS07665	COG1380	Effector of murein hydrolase LrgA
FOC88_RS07670	COG1346	cytolysis
FOC88_RS07685	COG5001	Diguanylate cyclase
FOC88_RS07685	COG3300	MHYT domain
FOC88_RS07690	COG0346	lactoylglutathione lyase activity
FOC88_RS07695	COG2267	carboxylic ester hydrolase activity
FOC88_RS07710	COG2364	Membrane
FOC88_RS07720	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC88_RS07725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC88_RS07730	COG2169	Transcriptional regulator
FOC88_RS07735	COG0708	Exodeoxyribonuclease III
FOC88_RS07740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC88_RS07745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC88_RS07750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC88_RS07755	COG1120	ATPase activity
FOC88_RS07760	COG2819	hydrolase of the alpha beta superfamily
FOC88_RS07770	COG1937	Protein conserved in bacteria
FOC88_RS07775	COG2608	mercury ion transmembrane transporter activity
FOC88_RS07780	COG2217	Heavy metal translocating P-type atpase
FOC88_RS07795	COG2116	formate transmembrane transporter activity
FOC88_RS07800	COG1408	metallophosphoesterase
FOC88_RS07815	COG1113	amino acid transport
FOC88_RS07825	COG2322	membrane
FOC88_RS07830	COG1979	alcohol dehydrogenase
FOC88_RS07835	COG1349	DNA-binding transcription factor activity
FOC88_RS07840	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC88_RS07845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC88_RS07845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC88_RS07845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC88_RS07850	COG1388	LysM domain
FOC88_RS07850	COG3584	3D domain protein
FOC88_RS07880	COG0464	growth
FOC88_RS07885	COG2860	membrane
FOC88_RS07890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC88_RS07895	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOC88_RS07900	COG0789	Transcriptional regulator
FOC88_RS07905	COG0174	glutamine synthetase
FOC88_RS07925	COG1396	sequence-specific DNA binding
FOC88_RS08015	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FOC88_RS08050	COG1595	DNA-templated transcription, initiation
FOC88_RS08205	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC88_RS08245	COG1695	Transcriptional regulator
FOC88_RS08265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC88_RS08275	COG0737	Belongs to the 5'-nucleotidase family
FOC88_RS08285	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC88_RS08290	COG3639	organic phosphonate transmembrane transporter activity
FOC88_RS08320	COG1132	(ABC) transporter
FOC88_RS08325	COG1132	(ABC) transporter
FOC88_RS08340	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC88_RS08340	COG3409	Peptidoglycan-binding domain 1 protein
FOC88_RS08350	COG0730	response to heat
FOC88_RS08365	COG1346	cytolysis
FOC88_RS08375	COG0583	DNA-binding transcription factor activity
FOC88_RS08385	COG1131	(ABC) transporter
FOC88_RS08395	COG1473	amidohydrolase
FOC88_RS08405	COG0785	Cytochrome C biogenesis protein
FOC88_RS08410	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC88_RS08470	COG0010	Belongs to the arginase family
FOC88_RS08475	COG1329	Transcriptional regulator
FOC88_RS08480	COG1902	pentaerythritol trinitrate reductase activity
FOC88_RS08485	COG0069	glutamate synthase activity
FOC88_RS08490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC88_RS08495	COG0346	lactoylglutathione lyase activity
FOC88_RS08500	COG0400	carboxylic ester hydrolase activity
FOC88_RS08505	COG5002	protein histidine kinase activity
FOC88_RS08515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC88_RS08565	COG0318	PFAM AMP-dependent synthetase and ligase
FOC88_RS08570	COG1268	BioY protein
FOC88_RS08575	COG0318	PFAM AMP-dependent synthetase and ligase
FOC88_RS08580	COG0183	Belongs to the thiolase family
FOC88_RS08595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC88_RS08635	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC88_RS08640	COG2274	protein secretion by the type I secretion system
FOC88_RS08650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC88_RS08680	COG0824	Thioesterase
FOC88_RS08685	COG4841	protein insertion into membrane
FOC88_RS08705	COG0745	RESPONSE REGULATOR receiver
FOC88_RS08710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC88_RS08715	COG1832	CoA-binding protein
FOC88_RS08720	COG0187	DNA topoisomerase II activity
FOC88_RS08725	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC88_RS08730	COG0673	inositol 2-dehydrogenase activity
FOC88_RS08740	COG1131	(ABC) transporter
FOC88_RS08760	COG1595	DNA-templated transcription, initiation
FOC88_RS08770	COG1316	TRANSCRIPTIONal
FOC88_RS08775	COG1301	dicarboxylic acid transport
FOC88_RS08780	COG4166	transmembrane transport
FOC88_RS08785	COG4166	transmembrane transport
FOC88_RS08795	COG4166	transmembrane transport
FOC88_RS08800	COG2226	methyltransferase
FOC88_RS08840	COG0697	spore germination
FOC88_RS08845	COG3383	formate dehydrogenase (NAD+) activity
FOC88_RS08850	COG2427	Protein of unknown function (DUF1641)
FOC88_RS08855	COG5609	conserved protein (DUF2294)
FOC88_RS08860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC88_RS08870	COG2116	formate transmembrane transporter activity
FOC88_RS08875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC88_RS08880	COG0303	'Molybdopterin
FOC88_RS08885	COG0314	molybdopterin synthase activity
FOC88_RS08895	COG0489	protein tyrosine kinase activity
FOC88_RS08910	COG3326	Membrane
FOC88_RS08915	COG2962	Rard protein
FOC88_RS08920	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOC88_RS08925	COG1657	PFAM Prenyltransferase squalene oxidase
FOC88_RS08935	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS08940	COG1012	belongs to the aldehyde dehydrogenase family
FOC88_RS08950	COG4145	pantothenate transmembrane transporter activity
FOC88_RS08965	COG0165	Argininosuccinate lyase
FOC88_RS08975	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS08995	COG1051	belongs to the nudix hydrolase family
FOC88_RS09005	COG0716	FMN binding
FOC88_RS09045	COG2720	vancomycin resistance protein
FOC88_RS09050	COG2514	catechol 2,3-dioxygenase activity
FOC88_RS09060	COG1285	pathogenesis
FOC88_RS09070	COG1024	Enoyl-CoA hydratase
FOC88_RS09075	COG1216	Glycosyl transferase, family 2
FOC88_RS09110	COG0277	FAD linked oxidase domain protein
FOC88_RS09115	COG0385	Bile acid
FOC88_RS09130	COG2808	Putative FMN-binding domain
FOC88_RS09140	COG0457	Tetratricopeptide repeat
FOC88_RS09150	COG0604	alcohol dehydrogenase
FOC88_RS09155	COG0640	Transcriptional regulator
FOC88_RS09180	COG0584	glycerophosphoryl diester phosphodiesterase
FOC88_RS09210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC88_RS09215	COG1164	Oligoendopeptidase f
FOC88_RS09220	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FOC88_RS09235	COG1193	negative regulation of DNA recombination
FOC88_RS09255	COG0583	DNA-binding transcription factor activity
FOC88_RS09290	COG0384	phenazine biosynthesis protein PhzF
FOC88_RS09295	COG3739	integral membrane protein
FOC88_RS09300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC88_RS09305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC88_RS09310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC88_RS09325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC88_RS09330	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC88_RS09360	COG2814	Major facilitator Superfamily
FOC88_RS09365	COG1113	amino acid transport
FOC88_RS09370	COG0604	alcohol dehydrogenase
FOC88_RS09405	COG2072	flavoprotein involved in K transport
FOC88_RS09445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC88_RS09455	COG1151	hydroxylamine reductase activity
FOC88_RS09480	COG3152	Membrane
FOC88_RS09500	COG1309	transcriptional regulator
FOC88_RS09515	COG1191	sigma factor activity
FOC88_RS09535	COG1733	regulation of RNA biosynthetic process
FOC88_RS09540	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC88_RS09545	COG0318	PFAM AMP-dependent synthetase and ligase
FOC88_RS09555	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS09565	COG0384	phenazine biosynthesis protein PhzF
FOC88_RS09585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC88_RS09605	COG1733	regulation of RNA biosynthetic process
FOC88_RS09610	COG1733	regulation of RNA biosynthetic process
FOC88_RS09615	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC88_RS09620	COG0673	inositol 2-dehydrogenase activity
FOC88_RS09625	COG2188	Transcriptional regulator
FOC88_RS09635	COG1393	Belongs to the ArsC family
FOC88_RS09665	COG0814	amino acid
FOC88_RS09705	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS09720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC88_RS09735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC88_RS09745	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOC88_RS09750	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC88_RS09760	COG1070	Carbohydrate kinase
FOC88_RS09765	COG2706	6-phosphogluconolactonase activity
FOC88_RS09770	COG3813	Protein conserved in bacteria
FOC88_RS09775	COG1357	PFAM Pentapeptide repeats (8 copies)
FOC88_RS09780	COG0697	spore germination
FOC88_RS09785	COG0789	Transcriptional regulator
FOC88_RS09790	COG1253	flavin adenine dinucleotide binding
FOC88_RS09820	COG0477	Major facilitator Superfamily
FOC88_RS09830	COG2226	methyltransferase
FOC88_RS09850	COG0628	permease
FOC88_RS09870	COG0577	efflux transmembrane transporter activity
FOC88_RS09870	COG1136	(ABC) transporter
FOC88_RS09880	COG0110	maltose O-acetyltransferase activity
FOC88_RS09885	COG0738	Major facilitator superfamily
FOC88_RS09890	COG1940	carbohydrate kinase activity
FOC88_RS09895	COG0346	lactoylglutathione lyase activity
FOC88_RS09930	COG1011	Hydrolase
FOC88_RS09955	COG1131	(ABC) transporter
FOC88_RS09965	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS09985	COG0778	Nitroreductase
FOC88_RS09990	COG1733	regulation of RNA biosynthetic process
FOC88_RS10005	COG0124	histidyl-tRNA synthetase
FOC88_RS10010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC88_RS10020	COG3620	sequence-specific DNA binding
FOC88_RS10030	COG1309	transcriptional regulator
FOC88_RS10035	COG2814	Major facilitator Superfamily
FOC88_RS10050	COG1288	antiporter activity
FOC88_RS10055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC88_RS10070	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC88_RS10105	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC88_RS10115	COG2031	fatty acid transporter
FOC88_RS10125	COG1309	transcriptional regulator
FOC88_RS10130	COG2076	Multidrug Resistance protein
FOC88_RS10150	COG1131	(ABC) transporter
FOC88_RS10155	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC88_RS10165	COG2814	Major facilitator Superfamily
FOC88_RS10170	COG1846	Transcriptional regulator
FOC88_RS10180	COG0477	Major facilitator Superfamily
FOC88_RS10220	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC88_RS10220	COG3409	Peptidoglycan-binding domain 1 protein
FOC88_RS10240	COG2207	Transcriptional regulator
FOC88_RS10240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC88_RS10245	COG0662	Cupin 2, conserved barrel domain protein
FOC88_RS10265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC88_RS10280	COG0531	amino acid
FOC88_RS10285	COG1522	sequence-specific DNA binding
FOC88_RS10290	COG1335	isochorismatase
FOC88_RS10300	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC88_RS10305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC88_RS10315	COG1760	l-serine dehydratase
FOC88_RS10320	COG1760	l-serine dehydratase
FOC88_RS10325	COG0814	amino acid
FOC88_RS10335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC88_RS10360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC88_RS10380	COG0457	Tetratricopeptide repeat
FOC88_RS10385	COG1609	Transcriptional regulator
FOC88_RS10390	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC88_RS10395	COG0561	phosphatase activity
FOC88_RS10400	COG0673	inositol 2-dehydrogenase activity
FOC88_RS10405	COG0738	Major facilitator superfamily
FOC88_RS10430	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC88_RS10440	COG0583	DNA-binding transcription factor activity
FOC88_RS10450	COG1139	Iron-sulfur cluster binding protein
FOC88_RS10455	COG1556	Lactate utilization protein
FOC88_RS10460	COG2271	Major facilitator Superfamily
FOC88_RS10465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC88_RS10475	COG3850	Histidine kinase
FOC88_RS10475	COG5002	protein histidine kinase activity
FOC88_RS10490	COG0577	efflux transmembrane transporter activity
FOC88_RS10495	COG1136	(ABC) transporter
FOC88_RS10510	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOC88_RS10515	COG0789	Transcriptional regulator
FOC88_RS10525	COG2309	aminopeptidase activity
FOC88_RS10540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC88_RS10550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC88_RS10555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC88_RS10580	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC88_RS10605	COG5002	protein histidine kinase activity
FOC88_RS10605	COG3850	Histidine kinase
FOC88_RS10610	COG0745	RESPONSE REGULATOR receiver
FOC88_RS10635	COG2814	Major facilitator Superfamily
FOC88_RS10680	COG2169	Transcriptional regulator
FOC88_RS10700	COG0346	lactoylglutathione lyase activity
FOC88_RS10715	COG1522	sequence-specific DNA binding
FOC88_RS10720	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS10725	COG1309	transcriptional regulator
FOC88_RS10730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC88_RS10730	COG3320	Male sterility
FOC88_RS10740	COG0456	acetyltransferase
FOC88_RS10745	COG0745	RESPONSE REGULATOR receiver
FOC88_RS10750	COG5002	protein histidine kinase activity
FOC88_RS10770	COG0640	Transcriptional regulator
FOC88_RS10775	COG0346	lactoylglutathione lyase activity
FOC88_RS10780	COG0798	PFAM Bile acid sodium symporter
FOC88_RS10790	COG0572	uridine kinase
FOC88_RS10810	COG4641	Protein conserved in bacteria
FOC88_RS10815	COG2267	carboxylic ester hydrolase activity
FOC88_RS10820	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC88_RS10835	COG5609	conserved protein (DUF2294)
FOC88_RS10840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC88_RS10850	COG0288	reversible hydration of carbon dioxide
FOC88_RS10855	COG0415	Belongs to the DNA photolyase family
FOC88_RS10890	COG0598	Magnesium transport protein CorA
FOC88_RS10895	COG1846	Transcriptional regulator
FOC88_RS10900	COG0583	DNA-binding transcription factor activity
FOC88_RS10920	COG1335	isochorismatase
FOC88_RS10925	COG2267	carboxylic ester hydrolase activity
FOC88_RS10930	COG0753	catalase activity
FOC88_RS10935	COG0737	Belongs to the 5'-nucleotidase family
FOC88_RS10965	COG1115	amino acid carrier protein
FOC88_RS10970	COG2066	Belongs to the glutaminase family
FOC88_RS10975	COG4191	Histidine kinase
FOC88_RS10980	COG0784	Response regulator, receiver
FOC88_RS10985	COG0697	spore germination
FOC88_RS10990	COG0531	amino acid
FOC88_RS11005	COG0281	malic enzyme
FOC88_RS11015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC88_RS11020	COG1114	Component of the transport system for branched-chain amino acids
FOC88_RS11025	COG0531	amino acid
FOC88_RS11030	COG0322	excinuclease ABC activity
FOC88_RS11045	COG2207	Transcriptional regulator
FOC88_RS11070	COG5002	protein histidine kinase activity
FOC88_RS11100	COG1396	sequence-specific DNA binding
FOC88_RS11105	COG0252	asparaginase activity
FOC88_RS11110	COG1027	Aspartate ammonia-lyase
FOC88_RS11120	COG1063	alcohol dehydrogenase
FOC88_RS11150	COG1113	amino acid transport
FOC88_RS11155	COG1280	lysine exporter protein (LysE YggA)
FOC88_RS11160	COG3403	YqcI/YcgG family
FOC88_RS11165	COG5577	PFAM Coat F domain
FOC88_RS11180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC88_RS11185	COG3848	Pyruvate phosphate dikinase
FOC88_RS11185	COG0574	Belongs to the PEP-utilizing enzyme family
FOC88_RS11200	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOC88_RS11230	COG1960	acyl-CoA dehydrogenase activity
FOC88_RS11240	COG0640	Transcriptional regulator
FOC88_RS11245	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC88_RS11260	COG1414	Transcriptional regulator
FOC88_RS11265	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC88_RS11270	COG1984	allophanate hydrolase subunit 2
FOC88_RS11345	COG4335	DNA alkylation repair
FOC88_RS11355	COG0833	amino acid
FOC88_RS11365	COG0730	response to heat
FOC88_RS11405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC88_RS11425	COG0456	acetyltransferase
FOC88_RS11430	COG2207	Transcriptional regulator
FOC88_RS11455	COG1136	(ABC) transporter
FOC88_RS11465	COG1725	Transcriptional regulator
FOC88_RS11495	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC88_RS11500	COG2814	Major facilitator Superfamily
FOC88_RS11505	COG2508	Transcriptional regulator
FOC88_RS11515	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC88_RS11530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC88_RS11535	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC88_RS11540	COG2723	6-phospho-beta-galactosidase activity
FOC88_RS11545	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC88_RS11550	COG1024	Enoyl-CoA hydratase
FOC88_RS11555	COG0183	Belongs to the thiolase family
FOC88_RS11560	COG0318	PFAM AMP-dependent synthetase and ligase
FOC88_RS11565	COG0824	Thioesterase
FOC88_RS11580	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC88_RS11600	COG1846	Transcriptional regulator
FOC88_RS11605	COG0778	Nitroreductase
FOC88_RS11635	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC88_RS11645	COG0753	catalase activity
FOC88_RS11650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC88_RS11660	COG0463	Glycosyl transferase, family 2
FOC88_RS11675	COG0463	Glycosyl transferase, family 2
FOC88_RS11700	COG0714	Associated with various cellular activities
FOC88_RS11720	COG0346	lactoylglutathione lyase activity
FOC88_RS11725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC88_RS11735	COG3279	Response regulator of the LytR AlgR family
FOC88_RS11745	COG4377	Putative membrane peptidase family (DUF2324)
FOC88_RS11760	COG3655	Transcriptional regulator
FOC88_RS11770	COG1785	Belongs to the alkaline phosphatase family
FOC88_RS11775	COG3239	Fatty acid desaturase
FOC88_RS11780	COG1690	Belongs to the RtcB family
FOC88_RS11785	COG0833	amino acid
FOC88_RS11790	COG1414	Transcriptional regulator
FOC88_RS11795	COG4187	Peptidase family M20/M25/M40
FOC88_RS11800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC88_RS11815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC88_RS11835	COG2329	Antibiotic biosynthesis monooxygenase
FOC88_RS11865	COG1070	Carbohydrate kinase
FOC88_RS11870	COG2390	Transcriptional regulator
FOC88_RS11880	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC88_RS11885	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC88_RS11890	COG1879	ABC-type sugar transport system periplasmic component
FOC88_RS11905	COG3829	transcription factor binding
FOC88_RS11905	COG3290	protein histidine kinase activity
FOC88_RS11915	COG1024	Enoyl-CoA hydratase
FOC88_RS11920	COG2610	gluconate transmembrane transporter activity
FOC88_RS11930	COG1388	LysM domain
FOC88_RS11930	COG3584	3D domain protein
FOC88_RS11965	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC88_RS11965	COG1605	Chorismate mutase
FOC88_RS11975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC88_RS11980	COG0287	Prephenate dehydrogenase
FOC88_RS11995	COG1309	transcriptional regulator
FOC88_RS12000	COG1033	growth of symbiont in host cell
FOC88_RS12000	COG2409	Drug exporters of the RND superfamily
FOC88_RS12010	COG0488	(ABC) transporter
FOC88_RS12015	COG1368	sulfuric ester hydrolase activity
FOC88_RS12020	COG0861	Integral membrane protein TerC family
FOC88_RS12040	COG4912	Dna alkylation repair
FOC88_RS12060	COG2318	DinB family
FOC88_RS12065	COG0697	spore germination
FOC88_RS12090	COG2746	aminoglycoside 3-N-acetyltransferase activity
FOC88_RS12130	COG1116	anion transmembrane transporter activity
FOC88_RS12135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC88_RS12140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC88_RS12145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC88_RS12155	COG0628	permease
FOC88_RS12195	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC88_RS12205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC88_RS12210	COG0436	Aminotransferase
FOC88_RS12250	COG2226	methyltransferase
FOC88_RS12265	COG2261	transglycosylase associated protein
FOC88_RS12285	COG0477	Major facilitator Superfamily
FOC88_RS12285	COG2814	Major facilitator Superfamily
FOC88_RS12290	COG4533	DNA binding
FOC88_RS12295	COG0789	Transcriptional regulator
FOC88_RS12300	COG1664	Polymer-forming cytoskeletal
FOC88_RS12310	COG2814	Major facilitator Superfamily
FOC88_RS12330	COG1307	EDD domain protein, DegV family
FOC88_RS12340	COG1164	Oligoendopeptidase f
FOC88_RS12370	COG0745	RESPONSE REGULATOR receiver
FOC88_RS12375	COG5002	protein histidine kinase activity
FOC88_RS12380	COG2936	dipeptidyl-peptidase activity
FOC88_RS12425	COG4948	Mandelate Racemase Muconate Lactonizing
FOC88_RS12435	COG4166	transmembrane transport
FOC88_RS12440	COG0519	Catalyzes the synthesis of GMP from XMP
FOC88_RS12445	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC88_RS12460	COG0586	Pfam SNARE associated Golgi protein
FOC88_RS12500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC88_RS12505	COG3938	Belongs to the proline racemase family
FOC88_RS12515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC88_RS12520	COG1012	belongs to the aldehyde dehydrogenase family
FOC88_RS12525	COG1115	amino acid carrier protein
FOC88_RS12530	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC88_RS12545	COG3397	chitin binding
FOC88_RS12570	COG4637	Psort location Cytoplasmic, score
FOC88_RS12590	COG0514	ATP-dependent DNA helicase (RecQ)
FOC88_RS12595	COG2105	PFAM AIG2 family protein
FOC88_RS12610	COG3973	AAA domain
FOC88_RS12660	COG0658	competence protein
FOC88_RS12660	COG2333	competence protein COMEC
FOC88_RS12685	COG2226	methyltransferase
FOC88_RS12690	COG2205	protein histidine kinase activity
FOC88_RS12705	COG1819	glycosyl
FOC88_RS12710	COG3397	chitin binding
FOC88_RS12715	COG2153	protein acetylation
FOC88_RS12745	COG0517	IMP dehydrogenase activity
FOC88_RS12745	COG4175	Glycine betaine
FOC88_RS12750	COG4176	ABC-type proline glycine betaine transport system permease component
FOC88_RS12780	COG0572	uridine kinase
FOC88_RS12785	COG0456	acetyltransferase
FOC88_RS12785	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC88_RS12790	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS12800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC88_RS12805	COG0022	dehydrogenase e1 component
FOC88_RS12810	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC88_RS12815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC88_RS12835	COG1349	DNA-binding transcription factor activity
FOC88_RS12855	COG3284	Transcriptional regulator
FOC88_RS12875	COG1309	transcriptional regulator
FOC88_RS12910	COG2959	enzyme of heme biosynthesis
FOC88_RS12925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC88_RS12970	COG0697	spore germination
FOC88_RS12980	COG0201	protein transport
FOC88_RS13000	COG3227	Zinc metalloprotease (Elastase)
FOC88_RS13005	COG1523	belongs to the glycosyl hydrolase 13 family
FOC88_RS13020	COG0076	glutamate decarboxylase activity
FOC88_RS13060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC88_RS13100	COG0322	excinuclease ABC activity
FOC88_RS13115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC88_RS13140	COG4667	esterase of the alpha-beta hydrolase superfamily
FOC88_RS13160	COG3878	Protein conserved in bacteria
FOC88_RS13185	COG1051	belongs to the nudix hydrolase family
FOC88_RS13190	COG0592	DNA-directed DNA polymerase activity
FOC88_RS13210	COG2223	nitrite transmembrane transporter activity
FOC88_RS13245	COG0697	spore germination
FOC88_RS13250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC88_RS13265	COG0584	glycerophosphoryl diester phosphodiesterase
FOC88_RS13280	COG2814	Major facilitator Superfamily
FOC88_RS13335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC88_RS13350	COG0671	phosphoesterase, PA-phosphatase related
FOC88_RS13355	COG0604	alcohol dehydrogenase
FOC88_RS13370	COG2205	protein histidine kinase activity
FOC88_RS13385	COG1122	ATPase activity
FOC88_RS13395	COG1794	racemase activity, acting on amino acids and derivatives
FOC88_RS13400	COG1819	glycosyl
FOC88_RS13410	COG5002	protein histidine kinase activity
FOC88_RS13415	COG0561	phosphatase activity
FOC88_RS13450	COG2124	cytochrome p450
FOC88_RS13500	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC88_RS13510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC88_RS13515	COG0460	homoserine dehydrogenase
FOC88_RS13535	COG0577	efflux transmembrane transporter activity
FOC88_RS13540	COG1136	(ABC) transporter
FOC88_RS13565	COG2205	protein histidine kinase activity
FOC88_RS13570	COG0745	RESPONSE REGULATOR receiver
FOC88_RS13580	COG3773	Cell wall hydrolase
FOC88_RS13595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC88_RS13610	COG1063	alcohol dehydrogenase
FOC88_RS13635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC88_RS13655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC88_RS13670	COG2226	methyltransferase
FOC88_RS13690	COG0693	protein deglycase activity
FOC88_RS13725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC88_RS13755	COG2207	Transcriptional regulator
FOC88_RS13780	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC88_RS13805	COG1686	Belongs to the peptidase S11 family
FOC88_RS13810	COG2318	DinB family
FOC88_RS13820	COG0572	uridine kinase
FOC88_RS13825	COG1247	-acetyltransferase
FOC88_RS13835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC88_RS13840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC88_RS13845	COG1024	Enoyl-CoA hydratase
FOC88_RS13850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC88_RS13855	COG0511	ligase activity, forming carbon-carbon bonds
FOC88_RS13860	COG0439	Biotin carboxylase
FOC88_RS13865	COG1960	acyl-CoA dehydrogenase activity
FOC88_RS13880	COG1309	transcriptional regulator
FOC88_RS13890	COG1131	(ABC) transporter
FOC88_RS13905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC88_RS13910	COG1252	NADH dehydrogenase
FOC88_RS13945	COG1309	transcriptional regulator
FOC88_RS13975	COG1876	peptidase activity
FOC88_RS13990	COG1476	TRANSCRIPTIONal
FOC88_RS13995	COG0457	Tetratricopeptide repeat
FOC88_RS14005	COG0737	Belongs to the 5'-nucleotidase family
FOC88_RS14020	COG3718	enzyme involved in inositol metabolism
FOC88_RS14025	COG0191	fructose-bisphosphate aldolase activity
FOC88_RS14050	COG0673	inositol 2-dehydrogenase activity
FOC88_RS14055	COG2814	Major facilitator Superfamily
FOC88_RS14060	COG1609	Transcriptional regulator
FOC88_RS14065	COG2367	Beta-lactamase
FOC88_RS14085	COG1595	DNA-templated transcription, initiation
FOC88_RS14100	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC88_RS14140	COG1846	Transcriptional regulator
FOC88_RS14145	COG3961	Belongs to the TPP enzyme family
FOC88_RS14160	COG3615	Tellurite resistance protein tehB
FOC88_RS14160	COG0500	methyltransferase
FOC88_RS14165	COG1136	(ABC) transporter
FOC88_RS14165	COG0577	efflux transmembrane transporter activity
FOC88_RS14180	COG1309	transcriptional regulator
FOC88_RS14210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC88_RS14245	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC88_RS14255	COG2971	BadF BadG BcrA BcrD
FOC88_RS14280	COG1649	PFAM Uncharacterised BCR, COG1649
FOC88_RS14305	COG1595	DNA-templated transcription, initiation
FOC88_RS14310	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FOC88_RS14320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC88_RS14350	COG1396	sequence-specific DNA binding
FOC88_RS14370	COG1132	(ABC) transporter
FOC88_RS14375	COG1132	(ABC) transporter
FOC88_RS14390	COG2258	MOSC domain
FOC88_RS14395	COG0583	DNA-binding transcription factor activity
FOC88_RS14410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC88_RS14415	COG0583	DNA-binding transcription factor activity
FOC88_RS14455	COG0561	phosphatase activity
FOC88_RS14460	COG0010	Belongs to the arginase family
FOC88_RS14475	COG1278	Cold shock
FOC88_RS14485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC88_RS14490	COG2226	methyltransferase
FOC88_RS14530	COG1247	-acetyltransferase
FOC88_RS14565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC88_RS14580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC88_RS14630	COG2814	Major facilitator Superfamily
FOC88_RS14635	COG0596	Alpha beta hydrolase
FOC88_RS14645	COG1136	(ABC) transporter
FOC88_RS14650	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC88_RS14655	COG1187	pseudouridine synthase activity
FOC88_RS14660	COG2329	Antibiotic biosynthesis monooxygenase
FOC88_RS14675	COG1115	amino acid carrier protein
FOC88_RS14685	COG2318	DinB family
FOC88_RS14695	COG0776	regulation of translation
FOC88_RS14710	COG2814	Major facilitator Superfamily
FOC88_RS14715	COG3251	PFAM MbtH domain protein
FOC88_RS14720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC88_RS14725	COG3433	isochorismatase activity
FOC88_RS14725	COG1535	isochorismatase
FOC88_RS14730	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOC88_RS14735	COG1169	isochorismate synthase
FOC88_RS14740	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS14745	COG2223	nitrite transmembrane transporter activity
FOC88_RS14885	COG0582	viral genome integration into host DNA
FOC88_RS14890	COG0419	ATPase involved in DNA repair
FOC88_RS14895	COG0420	3'-5' exonuclease activity
FOC88_RS14910	COG1024	Enoyl-CoA hydratase
FOC88_RS14915	COG1280	lysine exporter protein (LysE YggA)
FOC88_RS14925	COG2084	Dehydrogenase
FOC88_RS14930	COG1960	acyl-CoA dehydrogenase activity
FOC88_RS14935	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC88_RS14940	COG2079	MmgE PrpD family protein
FOC88_RS14945	COG0372	Belongs to the citrate synthase family
FOC88_RS14950	COG4841	protein insertion into membrane
FOC88_RS14955	COG2814	Major facilitator Superfamily
FOC88_RS14960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC88_RS14960	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC88_RS15000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC88_RS15055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC88_RS15060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC88_RS15065	COG0671	phosphoesterase, PA-phosphatase related
FOC88_RS15070	COG4326	sporulation control protein
FOC88_RS15110	COG1509	lysine 2,3-aminomutase activity
FOC88_RS15115	COG3829	transcription factor binding
FOC88_RS15120	COG0456	acetyltransferase
FOC88_RS15125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC88_RS15130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC88_RS15135	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC88_RS15140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC88_RS15155	COG5506	Protein of unknown function (DUF1694)
FOC88_RS15160	COG1012	belongs to the aldehyde dehydrogenase family
FOC88_RS15165	COG1253	flavin adenine dinucleotide binding
FOC88_RS15200	COG1174	glycine betaine transport
FOC88_RS15205	COG0517	IMP dehydrogenase activity
FOC88_RS15205	COG1125	glycine betaine transport
FOC88_RS15265	COG1064	alcohol dehydrogenase
FOC88_RS15275	COG2197	response regulator
FOC88_RS15280	COG2203	Gaf domain
FOC88_RS15280	COG4585	Histidine kinase
FOC88_RS15285	COG0668	transmembrane transport
FOC88_RS15290	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC88_RS15295	COG1051	belongs to the nudix hydrolase family
FOC88_RS15300	COG1335	isochorismatase
FOC88_RS15320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC88_RS15325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC88_RS15340	COG0367	asparagine synthase
FOC88_RS15345	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC88_RS15350	COG1999	signal sequence binding
FOC88_RS15355	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC88_RS15360	COG1307	EDD domain protein, DegV family
FOC88_RS15370	COG0805	protein transport
FOC88_RS15380	COG1272	protein, Hemolysin III
FOC88_RS15385	COG0204	Acyl-transferase
FOC88_RS15395	COG0768	penicillin binding
FOC88_RS15410	COG3250	beta-galactosidase activity
FOC88_RS15415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC88_RS15435	COG0546	phosphoglycolate phosphatase activity
FOC88_RS15445	COG4473	ABC transporter
FOC88_RS15450	COG1131	(ABC) transporter
FOC88_RS15460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC88_RS15465	COG0456	acetyltransferase
FOC88_RS15475	COG1794	racemase activity, acting on amino acids and derivatives
FOC88_RS15480	COG1454	alcohol dehydrogenase
FOC88_RS15485	COG2610	gluconate transmembrane transporter activity
FOC88_RS15510	COG0733	neurotransmitter:sodium symporter activity
FOC88_RS15525	COG5002	protein histidine kinase activity
FOC88_RS15525	COG3850	Histidine kinase
FOC88_RS15530	COG0745	RESPONSE REGULATOR receiver
FOC88_RS15535	COG0471	metal ion transport
FOC88_RS15540	COG1929	Belongs to the glycerate kinase type-1 family
FOC88_RS15595	COG5444	nuclease activity
FOC88_RS15625	COG5444	nuclease activity
FOC88_RS15650	COG1674	ftsk spoiiie
FOC88_RS15670	COG0017	Asparaginyl-tRNA synthetase
FOC88_RS15720	COG2521	methyltransferase
FOC88_RS15720	COG2136	Putative SAM-dependent methyltransferase
FOC88_RS15735	COG1413	lyase activity
FOC88_RS15740	COG0629	single-stranded DNA binding
FOC88_RS15755	COG0488	(ABC) transporter
FOC88_RS15760	COG1418	mRNA catabolic process
FOC88_RS15775	COG2359	stage V sporulation protein S
FOC88_RS15810	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC88_RS15815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC88_RS15820	COG2146	nitrite reductase [NAD(P)H] activity
FOC88_RS15825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC88_RS15825	COG1587	Uroporphyrinogen-III synthase
FOC88_RS15835	COG1648	precorrin-2 dehydrogenase activity
FOC88_RS15845	COG2223	nitrite transmembrane transporter activity
FOC88_RS15855	COG0314	molybdopterin synthase activity
FOC88_RS15860	COG0303	'Molybdopterin
FOC88_RS15865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC88_RS15870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC88_RS15875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC88_RS15885	COG1131	(ABC) transporter
FOC88_RS15895	COG2181	nitrate reductase activity
FOC88_RS15900	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC88_RS15905	COG1140	nitrate reductase beta subunit
FOC88_RS15910	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC88_RS15915	COG0714	Associated with various cellular activities
FOC88_RS15920	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOC88_RS15925	COG1305	Transglutaminase-like
FOC88_RS15930	COG0386	Belongs to the glutathione peroxidase family
FOC88_RS15950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOC88_RS15965	COG1595	DNA-templated transcription, initiation
FOC88_RS15970	COG0604	alcohol dehydrogenase
FOC88_RS15980	COG0346	lactoylglutathione lyase activity
FOC88_RS15985	COG1082	Xylose isomerase domain protein TIM barrel
FOC88_RS16005	COG2226	methyltransferase
FOC88_RS16030	COG3874	Sporulation protein YtfJ
FOC88_RS16055	COG0456	acetyltransferase
FOC88_RS16085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC88_RS16090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC88_RS16105	COG4106	trans-aconitate 2-methyltransferase activity
FOC88_RS16110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC88_RS16120	COG0561	phosphatase activity
FOC88_RS16140	COG2211	Major facilitator Superfamily
FOC88_RS16145	COG0154	amidase activity
FOC88_RS16155	COG1876	peptidase activity
FOC88_RS16165	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC88_RS16185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC88_RS16190	COG1114	Component of the transport system for branched-chain amino acids
FOC88_RS16205	COG1253	flavin adenine dinucleotide binding
FOC88_RS16210	COG2839	Protein conserved in bacteria
FOC88_RS16215	COG0702	epimerase
FOC88_RS16230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC88_RS16240	COG1607	acyl-coa hydrolase
FOC88_RS16245	COG3689	TIGRFAM TIGR03943 family protein
FOC88_RS16250	COG0701	Predicted permease
FOC88_RS16260	COG2244	polysaccharide biosynthetic process
FOC88_RS16265	COG0586	Pfam SNARE associated Golgi protein
FOC88_RS16270	COG1051	belongs to the nudix hydrolase family
FOC88_RS16275	COG5337	Spore coat protein CotH
FOC88_RS16285	COG0406	alpha-ribazole phosphatase activity
FOC88_RS16300	COG4166	transmembrane transport
FOC88_RS16310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC88_RS16320	COG0702	epimerase
FOC88_RS16330	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC88_RS16330	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC88_RS16385	COG0456	acetyltransferase
FOC88_RS16390	COG0523	cobalamin synthesis protein
FOC88_RS16395	COG4989	oxidoreductase activity
FOC88_RS16405	COG1231	oxidoreductase activity
FOC88_RS16415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC88_RS16430	COG0783	Belongs to the Dps family
FOC88_RS16435	COG3949	Membrane
FOC88_RS16450	COG0840	transmembrane signaling receptor activity
FOC88_RS16475	COG2814	Major facilitator Superfamily
FOC88_RS16480	COG0667	Aldo Keto reductase
FOC88_RS16485	COG0640	Transcriptional regulator
FOC88_RS16490	COG1404	Belongs to the peptidase S8 family
FOC88_RS16505	COG2002	toxin-antitoxin pair type II binding
FOC88_RS16510	COG0577	efflux transmembrane transporter activity
FOC88_RS16545	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC88_RS16555	COG1279	arginine transmembrane transporter activity
FOC88_RS16560	COG2814	Major facilitator Superfamily
FOC88_RS16570	COG1082	Xylose isomerase domain protein TIM barrel
FOC88_RS16585	COG0318	PFAM AMP-dependent synthetase and ligase
FOC88_RS16590	COG4264	IucA IucC family
FOC88_RS16600	COG1247	-acetyltransferase
FOC88_RS16605	COG1285	pathogenesis
FOC88_RS16620	COG5002	protein histidine kinase activity
FOC88_RS16625	COG0745	RESPONSE REGULATOR receiver
FOC88_RS16635	COG1316	TRANSCRIPTIONal
FOC88_RS16660	COG0460	homoserine dehydrogenase
FOC88_RS16675	COG5658	integral membrane protein
FOC88_RS16695	COG0300	oxidoreductase activity
FOC88_RS16705	COG5002	protein histidine kinase activity
FOC88_RS16710	COG0745	RESPONSE REGULATOR receiver
FOC88_RS16715	COG1132	(ABC) transporter
FOC88_RS16725	COG1388	LysM domain
FOC88_RS16725	COG0791	NLP P60 protein
FOC88_RS16740	COG1686	Belongs to the peptidase S11 family
FOC88_RS16745	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC88_RS16760	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC88_RS16765	COG4988	ABC transporter
FOC88_RS16770	COG1294	oxidase, subunit
FOC88_RS16775	COG1271	oxidase subunit
FOC88_RS16805	COG0583	DNA-binding transcription factor activity
FOC88_RS16825	COG0411	ABC transporter
FOC88_RS16835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC88_RS16840	COG2030	dehydratase
FOC88_RS16845	COG0318	PFAM AMP-dependent synthetase and ligase
FOC88_RS16860	COG0523	cobalamin synthesis protein
FOC88_RS16865	COG1231	oxidoreductase activity
FOC88_RS16875	COG0628	permease
FOC88_RS16890	COG0778	Nitroreductase
FOC88_RS16895	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC88_RS16900	COG1959	2 iron, 2 sulfur cluster binding
FOC88_RS16905	COG0583	DNA-binding transcription factor activity
FOC88_RS16910	COG0697	spore germination
FOC88_RS16915	COG4549	nuclear export factor GLE1
FOC88_RS16920	COG1276	copper resistance
FOC88_RS16920	COG2372	response to copper ion
FOC88_RS16930	COG1114	Component of the transport system for branched-chain amino acids
FOC88_RS16965	COG2132	Multicopper oxidase
FOC88_RS16970	COG0006	proline dipeptidase activity
FOC88_RS16995	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC88_RS17005	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC88_RS17010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC88_RS17020	COG2390	Transcriptional regulator
FOC88_RS17045	COG0531	amino acid
FOC88_RS17050	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC88_RS17065	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC88_RS17085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC88_RS17115	COG4166	transmembrane transport
FOC88_RS17135	COG0427	acetyl-CoA hydrolase
FOC88_RS17140	COG3279	Response regulator of the LytR AlgR family
FOC88_RS17150	COG3384	dioxygenase
FOC88_RS17155	COG2814	Major facilitator Superfamily
FOC88_RS17180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC88_RS17190	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC88_RS17195	COG0440	acetolactate synthase activity
FOC88_RS17200	COG0028	Belongs to the TPP enzyme family
FOC88_RS17205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC88_RS17215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC88_RS17230	COG2323	membrane
FOC88_RS17235	COG5566	PFAM Mor transcription activator
FOC88_RS17245	COG0733	neurotransmitter:sodium symporter activity
FOC88_RS17250	COG2244	polysaccharide biosynthetic process
FOC88_RS17265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC88_RS17270	COG2223	nitrite transmembrane transporter activity
FOC88_RS17275	COG4166	transmembrane transport
FOC88_RS17280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC88_RS17290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC88_RS17295	COG0477	Major facilitator Superfamily
FOC88_RS17305	COG1695	Transcriptional regulator
FOC88_RS17315	COG1966	Carbon starvation protein
FOC88_RS17330	COG2814	Major facilitator Superfamily
FOC88_RS17340	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC88_RS17345	COG1051	belongs to the nudix hydrolase family
FOC88_RS17400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC88_RS17405	COG0784	Response regulator, receiver
FOC88_RS17410	COG4191	Histidine kinase
FOC88_RS17415	COG0281	malic enzyme
FOC88_RS17420	COG1027	Aspartate ammonia-lyase
FOC88_RS17430	COG0528	UMP kinase activity
FOC88_RS17435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC88_RS17450	COG1131	(ABC) transporter
FOC88_RS17485	COG2733	membrane
FOC88_RS17515	COG0785	Cytochrome C biogenesis protein
FOC88_RS17535	COG3340	Belongs to the peptidase S51 family
FOC88_RS17540	COG0534	Mate efflux family protein
FOC88_RS17560	COG0114	fumarate hydratase activity
FOC88_RS17570	COG0789	Transcriptional regulator
FOC88_RS17575	COG1757	Na H antiporter
FOC88_RS17580	COG0438	transferase activity, transferring glycosyl groups
FOC88_RS17580	COG1216	Glycosyl transferase, family 2
FOC88_RS17590	COG0701	Predicted permease
FOC88_RS17595	COG0523	cobalamin synthesis protein
FOC88_RS17600	COG0697	spore germination
FOC88_RS17605	COG1802	Transcriptional regulator
FOC88_RS17635	COG0367	asparagine synthase
FOC88_RS17645	COG1846	Transcriptional regulator
FOC88_RS17665	COG0406	alpha-ribazole phosphatase activity
FOC88_RS17675	COG1686	Belongs to the peptidase S11 family
FOC88_RS17705	COG1234	tRNA 3'-trailer cleavage
FOC88_RS17720	COG3842	ATPase activity
FOC88_RS17725	COG0583	DNA-binding transcription factor activity
FOC88_RS17750	COG2329	Antibiotic biosynthesis monooxygenase
FOC88_RS17785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC88_RS17790	COG4786	Flagellar basal body rod
FOC88_RS17795	COG1419	protein localization to endoplasmic reticulum
FOC88_RS17800	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC88_RS17805	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC88_RS17815	COG1987	bacterial-type flagellum assembly
FOC88_RS17820	COG1338	Plays a role in the flagellum-specific transport system
FOC88_RS17830	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC88_RS17830	COG1776	CheC inhibitor of MCP methylation
FOC88_RS17835	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC88_RS17845	COG0741	lytic transglycosylase activity
FOC88_RS17850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC88_RS17870	COG0835	chemotaxis
FOC88_RS17870	COG0784	Response regulator, receiver
FOC88_RS17905	COG1157	protein secretion by the type III secretion system
FOC88_RS17915	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC88_RS17930	COG1558	bacterial-type flagellum-dependent cell motility
FOC88_RS17935	COG1815	bacterial-type flagellum-dependent cell motility
FOC88_RS17950	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOC88_RS17955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC88_RS17960	COG1256	bacterial-type flagellum assembly
FOC88_RS17980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC88_RS17995	COG1776	CheC inhibitor of MCP methylation
FOC88_RS17995	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC88_RS18000	COG2198	Histidine kinase
FOC88_RS18000	COG0643	Histidine kinase
FOC88_RS18005	COG2201	protein-glutamate methylesterase activity
FOC88_RS18010	COG1360	Flagellar Motor Protein
FOC88_RS18015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC88_RS18025	COG1923	regulation of RNA biosynthetic process
FOC88_RS18045	COG2814	Major facilitator Superfamily
FOC88_RS18080	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC88_RS18085	COG2323	membrane
FOC88_RS18095	COG0789	Transcriptional regulator
FOC88_RS18095	COG4978	Transcriptional regulator
FOC88_RS18100	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC88_RS18105	COG0475	glutathione-regulated potassium exporter activity
FOC88_RS18115	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC88_RS18120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC88_RS18125	COG3162	membrane
FOC88_RS18140	COG1280	lysine exporter protein (LysE YggA)
FOC88_RS18145	COG3403	YqcI/YcgG family
FOC88_RS18180	COG0328	RNA-DNA hybrid ribonuclease activity
FOC88_RS18200	COG0454	-acetyltransferase
FOC88_RS18215	COG0438	transferase activity, transferring glycosyl groups
FOC88_RS18220	COG1215	transferase activity, transferring glycosyl groups
FOC88_RS18235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC88_RS18260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC88_RS18275	COG0754	glutathionylspermidine amidase activity
FOC88_RS18310	COG0456	acetyltransferase
FOC88_RS18320	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC88_RS18325	COG2311	Membrane
FOC88_RS18330	COG2233	PERMEase
FOC88_RS18340	COG0024	Methionine aminopeptidase
FOC88_RS18345	COG3173	Aminoglycoside phosphotransferase
FOC88_RS18355	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC88_RS18360	COG1199	ATP-dependent helicase activity
FOC88_RS18370	COG0116	Belongs to the methyltransferase superfamily
FOC88_RS18430	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC88_RS18430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC88_RS18440	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC88_RS18445	COG3935	DnaD domain protein
FOC88_RS18465	COG1199	ATP-dependent helicase activity
FOC88_RS18465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC88_RS18500	COG0438	transferase activity, transferring glycosyl groups
FOC88_RS18505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC88_RS18520	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC88_RS18525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC88_RS18535	COG2738	Putative neutral zinc metallopeptidase
FOC88_RS18550	COG4347	Protein of unknown function (DUF1405)
FOC88_RS18560	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOC88_RS18580	COG0457	Tetratricopeptide repeat
FOC88_RS18585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC88_RS18605	COG0142	geranyltranstransferase activity
FOC88_RS18615	COG0142	geranyltranstransferase activity
FOC88_RS18630	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC88_RS18705	COG0492	ferredoxin-NADP+ reductase activity
FOC88_RS18725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC88_RS18730	COG4862	establishment of competence for transformation
FOC88_RS18740	COG1408	metallophosphoesterase
FOC88_RS18750	COG1266	CAAX protease self-immunity
FOC88_RS18755	COG0514	ATP-dependent DNA helicase (RecQ)
FOC88_RS18765	COG1141	Ferredoxin
FOC88_RS18770	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOC88_RS18780	COG4942	peptidase
FOC88_RS18785	COG2096	Adenosyltransferase
FOC88_RS18790	COG5002	protein histidine kinase activity
FOC88_RS18795	COG0745	RESPONSE REGULATOR receiver
FOC88_RS18800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC88_RS18805	COG1333	cytochrome c biogenesis protein
FOC88_RS18815	COG1187	pseudouridine synthase activity
FOC88_RS18820	COG0700	Nucleoside recognition
FOC88_RS18825	COG2715	membrane protein required for spore maturation
FOC88_RS18830	COG1686	Belongs to the peptidase S11 family
FOC88_RS18835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC88_RS18850	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOC88_RS18850	COG0392	lysyltransferase activity
FOC88_RS18870	COG5002	protein histidine kinase activity
FOC88_RS18875	COG0582	viral genome integration into host DNA
FOC88_RS18885	COG1801	Protein of unknown function DUF72
FOC88_RS18890	COG3852	Histidine kinase
FOC88_RS18905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC88_RS18910	COG1392	Phosphate transport regulator
FOC88_RS18915	COG0306	phosphate transporter
FOC88_RS18920	COG0730	response to heat
FOC88_RS18960	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC88_RS18970	COG1114	Component of the transport system for branched-chain amino acids
FOC88_RS18980	COG2197	response regulator
FOC88_RS18985	COG4585	Histidine kinase
FOC88_RS18990	COG4758	membrane
FOC88_RS19005	COG1757	Na H antiporter
FOC88_RS19025	COG0733	neurotransmitter:sodium symporter activity
FOC88_RS19030	COG1648	precorrin-2 dehydrogenase activity
FOC88_RS19050	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC88_RS19055	COG0529	Catalyzes the synthesis of activated sulfate
FOC88_RS19075	COG0019	diaminopimelate decarboxylase activity
FOC88_RS19085	COG1368	sulfuric ester hydrolase activity
FOC88_RS19090	COG1183	phosphatidylcholine synthase activity
FOC88_RS19105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC88_RS19180	COG0440	acetolactate synthase activity
FOC88_RS19185	COG0028	Belongs to the TPP enzyme family
FOC88_RS19190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC88_RS19210	COG3874	Sporulation protein YtfJ
FOC88_RS19215	COG4709	membrane
FOC88_RS19220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC88_RS19225	COG1301	dicarboxylic acid transport
FOC88_RS19235	COG1846	Transcriptional regulator
FOC88_RS19250	COG1968	undecaprenyl-diphosphatase activity
FOC88_RS19255	COG0534	Mate efflux family protein
FOC88_RS19275	COG3173	Aminoglycoside phosphotransferase
FOC88_RS19290	COG0716	FMN binding
FOC88_RS19315	COG1696	Membrane protein involved in D-alanine export
FOC88_RS19325	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC88_RS19330	COG2070	2-Nitropropane dioxygenase
FOC88_RS19335	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC88_RS19345	COG1335	isochorismatase
FOC88_RS19355	COG1522	sequence-specific DNA binding
FOC88_RS19370	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC88_RS19375	COG1131	(ABC) transporter
FOC88_RS19385	COG1131	(ABC) transporter
FOC88_RS19390	COG1725	Transcriptional regulator
FOC88_RS19395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC88_RS19415	COG1780	Probably involved in ribonucleotide reductase function
FOC88_RS19445	COG4873	Protein conserved in bacteria
FOC88_RS19460	COG0720	synthase
FOC88_RS19470	COG5002	protein histidine kinase activity
FOC88_RS19475	COG2318	DinB family
FOC88_RS19485	COG1846	Transcriptional regulator
FOC88_RS19490	COG3852	Histidine kinase
FOC88_RS19500	COG2861	carbohydrate metabolic process
FOC88_RS19510	COG0235	Class ii aldolase
FOC88_RS19520	COG1349	DNA-binding transcription factor activity
FOC88_RS19545	COG3842	ATPase activity
FOC88_RS19550	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC88_RS19565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC88_RS19575	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOC88_RS19580	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS19600	COG2030	dehydratase
FOC88_RS19610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC88_RS19615	COG0861	Integral membrane protein TerC family
FOC88_RS19620	COG2116	formate transmembrane transporter activity
FOC88_RS19630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOC88_RS19650	COG2186	Transcriptional regulator
FOC88_RS19655	COG5002	protein histidine kinase activity
FOC88_RS19660	COG0745	RESPONSE REGULATOR receiver
FOC88_RS19670	COG3835	regulator
FOC88_RS19675	COG0277	FAD linked oxidase domain protein
FOC88_RS19680	COG0247	lactate metabolic process
FOC88_RS19685	COG2340	Cysteine-rich secretory protein family
FOC88_RS19695	COG0564	pseudouridine synthase activity
FOC88_RS19705	COG2409	Drug exporters of the RND superfamily
FOC88_RS19715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC88_RS19720	COG1177	transmembrane transport
FOC88_RS19725	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC88_RS19735	COG1012	belongs to the aldehyde dehydrogenase family
FOC88_RS19770	COG0681	Belongs to the peptidase S26 family
FOC88_RS19775	COG1686	Belongs to the peptidase S11 family
FOC88_RS19785	COG2226	methyltransferase
FOC88_RS19845	COG1476	TRANSCRIPTIONal
FOC88_RS19855	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC88_RS19905	COG5634	Uncharacterized conserved protein (DUF2278)
FOC88_RS19910	COG1620	l-lactate permease
FOC88_RS19945	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC88_RS19945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC88_RS19955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC88_RS19960	COG5492	domain, Protein
FOC88_RS19975	COG2382	esterase
FOC88_RS19985	COG2153	protein acetylation
FOC88_RS20030	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC88_RS20045	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC88_RS20065	COG0463	Glycosyl transferase, family 2
FOC88_RS20065	COG0457	Tetratricopeptide repeat
FOC88_RS20085	COG1216	Glycosyl transferase, family 2
FOC88_RS20085	COG0463	Glycosyl transferase, family 2
FOC88_RS20090	COG0772	Belongs to the SEDS family
FOC88_RS20105	COG0564	pseudouridine synthase activity
FOC88_RS20115	COG2357	RelA SpoT domain protein
FOC88_RS20125	COG4116	CYTH
FOC88_RS20130	COG2346	COG2346, Truncated hemoglobins
FOC88_RS20145	COG1164	Oligoendopeptidase f
FOC88_RS20155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC88_RS20160	COG4862	establishment of competence for transformation
FOC88_RS20165	COG0861	Integral membrane protein TerC family
FOC88_RS20180	COG4166	transmembrane transport
FOC88_RS20185	COG0534	Mate efflux family protein
FOC88_RS20190	COG4608	Belongs to the ABC transporter superfamily
FOC88_RS20195	COG0444	Belongs to the ABC transporter superfamily
FOC88_RS20200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC88_RS20205	COG0601	transmembrane transport
FOC88_RS20210	COG4166	transmembrane transport
FOC88_RS20220	COG0180	Tryptophanyl-tRNA synthetase
FOC88_RS20230	COG5504	Zn-dependent protease
FOC88_RS20235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC88_RS20240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC88_RS20255	COG2267	carboxylic ester hydrolase activity
FOC88_RS20265	COG0542	response to heat
FOC88_RS20275	COG0561	phosphatase activity
FOC88_RS20290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC88_RS20300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC88_RS20310	COG2996	Protein conserved in bacteria
FOC88_RS20330	COG0004	ammonium transporteR
FOC88_RS20335	COG0753	catalase activity
FOC88_RS20345	COG0367	asparagine synthase
FOC88_RS20370	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC88_RS20430	COG0398	Pfam SNARE associated Golgi protein
FOC88_RS20435	COG4903	ComK protein
FOC88_RS20460	COG2224	Isocitrate lyase
FOC88_RS20465	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC88_RS20485	COG0697	spore germination
FOC88_RS20490	COG0501	Belongs to the peptidase M48B family
FOC88_RS20515	COG0745	RESPONSE REGULATOR receiver
FOC88_RS20520	COG2205	protein histidine kinase activity
FOC88_RS20535	COG3708	Transcriptional regulator
FOC88_RS20535	COG2207	Transcriptional regulator
FOC88_RS20540	COG1595	DNA-templated transcription, initiation
FOC88_RS20550	COG1078	dGTPase activity
FOC88_RS20555	COG1408	metallophosphoesterase
FOC88_RS20575	COG0318	PFAM AMP-dependent synthetase and ligase
FOC88_RS20585	COG0095	Lipoate-protein ligase
FOC88_RS20590	COG1234	tRNA 3'-trailer cleavage
FOC88_RS20600	COG1609	Transcriptional regulator
FOC88_RS20605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC88_RS20625	COG1511	domain protein
FOC88_RS20630	COG1309	transcriptional regulator
FOC88_RS20675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC88_RS20680	COG2329	Antibiotic biosynthesis monooxygenase
FOC88_RS20685	COG3428	Bacterial PH domain
FOC88_RS20690	COG3402	PFAM membrane-flanked domain
FOC88_RS20730	COG3428	Bacterial PH domain
FOC88_RS20735	COG3402	PFAM membrane-flanked domain
FOC88_RS20745	COG1309	transcriptional regulator
FOC88_RS20760	COG4473	ABC transporter
FOC88_RS20765	COG1131	(ABC) transporter
FOC88_RS20770	COG0537	adenosine 5'-monophosphoramidase activity
FOC88_RS20775	COG4980	gas vesicle protein
FOC88_RS20795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC88_RS20800	COG3973	AAA domain
FOC88_RS20810	COG0477	Major facilitator Superfamily
FOC88_RS20815	COG0477	Major facilitator Superfamily
FOC88_RS20830	COG0772	Belongs to the SEDS family
FOC88_RS20855	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC88_RS20865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC88_RS20870	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC88_RS20890	COG2267	carboxylic ester hydrolase activity
FOC88_RS20900	COG0346	lactoylglutathione lyase activity
FOC88_RS20905	COG0346	lactoylglutathione lyase activity
FOC88_RS20920	COG5444	nuclease activity
FOC88_RS20940	COG4717	serine-type aminopeptidase activity
FOC88_RS20945	COG0420	3'-5' exonuclease activity
FOC88_RS21000	COG0784	Response regulator, receiver
FOC88_RS21000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC88_RS21000	COG2198	Histidine kinase
FOC88_RS21000	COG2205	protein histidine kinase activity
FOC88_RS21005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC88_RS21010	COG2208	phosphoserine phosphatase activity
FOC88_RS21020	COG1191	sigma factor activity
FOC88_RS21045	COG3237	CsbD-like
FOC88_RS21095	COG3437	response regulator, receiver
FOC88_RS21095	COG2770	Histidine kinase
FOC88_RS21110	COG1959	2 iron, 2 sulfur cluster binding
FOC88_RS21120	COG2376	Dihydroxyacetone kinase
FOC88_RS21130	COG2376	Dihydroxyacetone kinase
FOC88_RS21150	COG1183	phosphatidylcholine synthase activity
FOC88_RS21165	COG1309	transcriptional regulator
FOC88_RS21170	COG3320	Male sterility
FOC88_RS21170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC88_RS21215	COG0477	Major facilitator Superfamily
FOC88_RS21255	COG0305	Participates in initiation and elongation during chromosome replication
FOC88_RS21275	COG4978	Transcriptional regulator
FOC88_RS21275	COG0789	Transcriptional regulator
FOC88_RS21335	COG3181	Tripartite tricarboxylate transporter family receptor
FOC88_RS21340	COG4565	transcriptional regulatory protein
FOC88_RS21350	COG0477	Major facilitator Superfamily
FOC88_RS21365	COG4608	Belongs to the ABC transporter superfamily
FOC88_RS21370	COG0444	Belongs to the ABC transporter superfamily
FOC88_RS21375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC88_RS21380	COG0601	transmembrane transport
FOC88_RS21445	COG1363	Peptidase, m42
FOC88_RS21475	COG1024	Enoyl-CoA hydratase
FOC88_RS21495	COG4196	transglutaminase domain protein
FOC88_RS21500	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC88_RS21510	COG2244	polysaccharide biosynthetic process
FOC88_RS21515	COG0653	protein targeting
FOC88_RS21535	COG0659	secondary active sulfate transmembrane transporter activity
FOC88_RS21550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC88_RS21555	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC88_RS21555	COG3409	Peptidoglycan-binding domain 1 protein
FOC88_RS21565	COG0561	phosphatase activity
FOC88_RS21575	COG3527	Alpha-acetolactate decarboxylase
FOC88_RS21580	COG0028	Belongs to the TPP enzyme family
FOC88_RS21610	COG0189	ligase activity
FOC88_RS21625	COG1126	abc transporter atp-binding protein
FOC88_RS21630	COG0765	amino acid transport
FOC88_RS21635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC88_RS21640	COG1132	(ABC) transporter
FOC88_RS21645	COG1132	(ABC) transporter
FOC88_RS21650	COG1012	belongs to the aldehyde dehydrogenase family
FOC88_RS21660	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC88_RS21665	COG0531	amino acid
FOC88_RS21675	COG0693	protein deglycase activity
FOC88_RS21675	COG0753	catalase activity
FOC88_RS21680	COG0693	protein deglycase activity
FOC88_RS21690	COG2211	Major facilitator Superfamily
FOC88_RS21695	COG4533	DNA binding
FOC88_RS21705	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC88_RS21715	COG1733	regulation of RNA biosynthetic process
FOC88_RS21720	COG2814	Major facilitator Superfamily
FOC88_RS21725	COG1309	transcriptional regulator
FOC88_RS21730	COG2076	Multidrug Resistance protein
FOC88_RS21745	COG1522	sequence-specific DNA binding
FOC88_RS21765	COG2259	Doxx family
FOC88_RS21775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC88_RS21775	COG1263	PTS System
FOC88_RS21785	COG1737	Transcriptional regulator
FOC88_RS21795	COG0475	glutathione-regulated potassium exporter activity
FOC88_RS21800	COG0531	amino acid
FOC88_RS21835	COG0586	Pfam SNARE associated Golgi protein
FOC88_RS21870	COG3546	catalase activity
FOC88_RS21875	COG1114	Component of the transport system for branched-chain amino acids
FOC88_RS21890	COG5522	Integral membrane protein (intg_mem_TP0381)
FOC88_RS21900	COG1136	(ABC) transporter
FOC88_RS21905	COG0577	efflux transmembrane transporter activity
FOC88_RS21910	COG1388	LysM domain
FOC88_RS21910	COG3584	3D domain protein
FOC88_RS21930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC88_RS21935	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC88_RS21940	COG3711	transcriptional antiterminator
FOC88_RS21940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC88_RS21955	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC88_RS21960	COG0604	alcohol dehydrogenase
FOC88_RS21965	COG1316	TRANSCRIPTIONal
FOC88_RS21975	COG0730	response to heat
FOC88_RS21980	COG2210	Belongs to the sulfur carrier protein TusA family
FOC88_RS21990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC88_RS21990	COG0425	Belongs to the sulfur carrier protein TusA family
FOC88_RS21995	COG0425	Belongs to the sulfur carrier protein TusA family
FOC88_RS22000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC88_RS22000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC88_RS22005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC88_RS22005	COG0425	Belongs to the sulfur carrier protein TusA family
FOC88_RS22010	COG1937	Protein conserved in bacteria
FOC88_RS22015	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC88_RS22025	COG3591	Belongs to the peptidase S1B family
FOC88_RS22030	COG2719	SpoVR family
FOC88_RS22035	COG0778	Nitroreductase
FOC88_RS22075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC88_RS22085	COG1609	Transcriptional regulator
FOC88_RS22090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC88_RS22090	COG1263	PTS System
FOC88_RS22095	COG1621	beta-fructofuranosidase activity
FOC88_RS22100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC88_RS22110	COG1376	ErfK ybiS ycfS ynhG family protein
FOC88_RS22115	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS22120	COG2252	PERMEase
FOC88_RS22145	COG1846	Transcriptional regulator
FOC88_RS22150	COG2814	Major facilitator Superfamily
FOC88_RS22155	COG2205	protein histidine kinase activity
FOC88_RS22195	COG0351	phosphomethylpyrimidine kinase
FOC88_RS22200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC88_RS22210	COG2104	thiamine diphosphate biosynthetic process
FOC88_RS22215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC88_RS22220	COG0352	thiamine-phosphate diphosphorylase activity
FOC88_RS22225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC88_RS22230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC88_RS22235	COG1116	anion transmembrane transporter activity
FOC88_RS22240	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC88_RS22260	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOC88_RS22380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC88_RS22385	COG0581	inorganic phosphate transmembrane transporter activity
FOC88_RS22390	COG0573	inorganic phosphate transmembrane transporter activity
FOC88_RS22395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC88_RS22400	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC88_RS22400	COG1918	ferrous iron import across plasma membrane
FOC88_RS22405	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC88_RS22410	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC88_RS22420	COG0531	amino acid
FOC88_RS22425	COG0697	spore germination
FOC88_RS22430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC88_RS22445	COG4990	cell redox homeostasis
FOC88_RS22450	COG0833	amino acid
FOC88_RS22455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC88_RS22460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC88_RS22475	COG0475	glutathione-regulated potassium exporter activity
FOC88_RS22475	COG0569	domain protein
FOC88_RS22485	COG2153	protein acetylation
FOC88_RS22500	COG2252	PERMEase
FOC88_RS22505	COG1113	amino acid transport
FOC88_RS22520	COG1114	Component of the transport system for branched-chain amino acids
FOC88_RS22525	COG3104	oligopeptide transport
FOC88_RS22540	COG1476	TRANSCRIPTIONal
FOC88_RS22545	COG1388	LysM domain
FOC88_RS22545	COG3584	3D domain protein
FOC88_RS22550	COG0840	transmembrane signaling receptor activity
FOC88_RS22580	COG3568	Endonuclease Exonuclease Phosphatase
FOC88_RS22595	COG1063	alcohol dehydrogenase
FOC88_RS22615	COG1879	ABC-type sugar transport system periplasmic component
FOC88_RS22620	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC88_RS22635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC88_RS22640	COG1609	Transcriptional regulator
FOC88_RS22645	COG0477	Major facilitator Superfamily
FOC88_RS22650	COG1846	Transcriptional regulator
FOC88_RS22655	COG2271	Major facilitator Superfamily
FOC88_RS22665	COG4608	Belongs to the ABC transporter superfamily
FOC88_RS22670	COG0601	transmembrane transport
FOC88_RS22695	COG0659	secondary active sulfate transmembrane transporter activity
FOC88_RS22710	COG5002	protein histidine kinase activity
FOC88_RS22715	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC88_RS22720	COG2378	regulation of single-species biofilm formation
FOC88_RS22740	COG1595	DNA-templated transcription, initiation
FOC88_RS22755	COG0833	amino acid
FOC88_RS22760	COG0765	amino acid transport
FOC88_RS22765	COG0765	amino acid transport
FOC88_RS22770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC88_RS22775	COG1126	abc transporter atp-binding protein
FOC88_RS22780	COG1115	amino acid carrier protein
FOC88_RS22785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC88_RS22795	COG0697	spore germination
FOC88_RS22810	COG0366	Alpha amylase catalytic
FOC88_RS22815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC88_RS22815	COG1263	PTS System
FOC88_RS22820	COG2188	Transcriptional regulator
FOC88_RS22825	COG0531	amino acid
FOC88_RS22845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC88_RS22850	COG0714	Associated with various cellular activities
FOC88_RS22855	COG4548	von Willebrand factor, type A
FOC88_RS22865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC88_RS22870	COG0156	8-amino-7-oxononanoate synthase activity
FOC88_RS22875	COG2226	methyltransferase
FOC88_RS22885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC88_RS22890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC88_RS22895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC88_RS22900	COG3104	oligopeptide transport
FOC88_RS22915	COG1620	l-lactate permease
FOC88_RS22920	COG1027	Aspartate ammonia-lyase
FOC88_RS22925	COG1253	flavin adenine dinucleotide binding
FOC88_RS22930	COG0346	lactoylglutathione lyase activity
FOC88_RS22935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC88_RS22940	COG1316	TRANSCRIPTIONal
FOC88_RS22945	COG2720	vancomycin resistance protein
FOC88_RS22965	COG3227	Zinc metalloprotease (Elastase)
FOC88_RS22980	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC88_RS22985	COG2217	Heavy metal translocating P-type atpase
FOC88_RS22990	COG0640	Transcriptional regulator
FOC88_RS22995	COG0531	amino acid
FOC88_RS23010	COG2427	Protein of unknown function (DUF1641)
FOC88_RS23015	COG3383	formate dehydrogenase (NAD+) activity
FOC88_RS23020	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC88_RS23025	COG0456	acetyltransferase
FOC88_RS23025	COG0454	-acetyltransferase
FOC88_RS23030	COG0745	RESPONSE REGULATOR receiver
FOC88_RS23035	COG5002	protein histidine kinase activity
FOC88_RS23045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC88_RS23060	COG0281	malic enzyme
FOC88_RS23065	COG3493	citrate carrier protein
FOC88_RS23070	COG4565	transcriptional regulatory protein
FOC88_RS23075	COG3290	protein histidine kinase activity
FOC88_RS23085	COG4990	cell redox homeostasis
FOC88_RS23095	COG5002	protein histidine kinase activity
FOC88_RS23100	COG0745	RESPONSE REGULATOR receiver
FOC88_RS23105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC88_RS23115	COG0395	ABC-type sugar transport system, permease component
FOC88_RS23120	COG1175	transmembrane transport
FOC88_RS23125	COG3842	ATPase activity
FOC88_RS23130	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC88_RS23150	COG2851	Citrate transporter
FOC88_RS23155	COG4565	transcriptional regulatory protein
FOC88_RS23160	COG3290	protein histidine kinase activity
FOC88_RS23170	COG2268	Band 7 protein
FOC88_RS23175	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC88_RS23185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC88_RS23205	COG2766	serine protein kinase
FOC88_RS23215	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC88_RS23225	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC88_RS23235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC88_RS23240	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC88_RS23355	COG0735	belongs to the Fur family
FOC88_RS23360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC88_RS23380	COG4555	ABC transporter
FOC88_RS23390	COG0069	glutamate synthase activity
FOC88_RS23390	COG0070	glutamate synthase
FOC88_RS23390	COG0067	glutamate synthase
FOC88_RS23395	COG4129	membrane
FOC88_RS23400	COG1132	(ABC) transporter
FOC88_RS23425	COG1194	a g-specific adenine glycosylase
FOC88_RS23430	COG1988	membrane-bound metal-dependent
FOC88_RS23460	COG1090	epimerase
FOC88_RS23465	COG1228	amidohydrolase
FOC88_RS23485	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC88_RS23505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC88_RS23505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC88_RS23515	COG0463	Glycosyl transferase, family 2
FOC88_RS23530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC88_RS23535	COG1263	PTS System
FOC88_RS23535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC88_RS23565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC88_RS23580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC88_RS23585	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC88_RS23605	COG0535	radical SAM domain protein
FOC88_RS23615	COG0387	Pfam Sodium calcium exchanger
FOC88_RS23620	COG3871	stress protein (general stress protein 26)
FOC88_RS23635	COG0586	Pfam SNARE associated Golgi protein
FOC88_RS23645	COG0681	Belongs to the peptidase S26 family
FOC88_RS23660	COG0697	spore germination
FOC88_RS23665	COG2217	Heavy metal translocating P-type atpase
FOC88_RS23670	COG1295	ribonuclease BN
FOC88_RS23680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC88_RS23695	COG3853	Toxic anion resistance protein (TelA)
FOC88_RS23705	COG0861	Integral membrane protein TerC family
FOC88_RS23710	COG2310	stress, protein
FOC88_RS23715	COG2310	stress, protein
FOC88_RS23720	COG2310	stress, protein
FOC88_RS23750	COG2270	Major facilitator Superfamily
FOC88_RS23800	COG0488	(ABC) transporter
FOC88_RS23805	COG1116	anion transmembrane transporter activity
FOC88_RS23815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC88_RS23830	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC88_RS23860	COG1263	PTS System
FOC88_RS23860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC88_RS23860	COG2190	(PTS) system
FOC88_RS23865	COG0366	Alpha amylase catalytic
FOC88_RS23905	COG0840	transmembrane signaling receptor activity
FOC88_RS23915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC88_RS23920	COG0765	amino acid transport
FOC88_RS23930	COG0723	plastoquinol--plastocyanin reductase activity
FOC88_RS23930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC88_RS23935	COG2814	Major facilitator Superfamily
FOC88_RS23940	COG3541	Predicted nucleotidyltransferase
FOC88_RS23995	COG0166	Belongs to the GPI family
FOC88_RS24010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC88_RS24015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC88_RS24020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC88_RS24040	COG0450	alkyl hydroperoxide reductase
FOC88_RS24055	COG1473	amidohydrolase
FOC88_RS24085	COG4807	Protein conserved in bacteria
FOC88_RS24095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC88_RS24100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC88_RS24105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC88_RS24120	COG2309	aminopeptidase activity
FOC88_RS24125	COG2076	Multidrug Resistance protein
FOC88_RS24130	COG1012	belongs to the aldehyde dehydrogenase family
FOC88_RS24140	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC88_RS24145	COG0546	phosphoglycolate phosphatase activity
FOC88_RS24150	COG1597	lipid kinase activity
FOC88_RS24170	COG4682	membrane
FOC88_RS24175	COG1846	Transcriptional regulator
FOC88_RS24180	COG0003	Pfam Anion-transporting ATPase
FOC88_RS24195	COG1464	Belongs to the NlpA lipoprotein family
FOC88_RS24200	COG2011	ABC-type metal ion transport system permease component
FOC88_RS24205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC88_RS24210	COG1335	isochorismatase
FOC88_RS24230	COG4851	CamS sex pheromone cAM373 precursor
FOC88_RS24240	COG0210	DNA helicase
FOC88_RS24265	COG0151	Belongs to the GarS family
FOC88_RS24275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC88_RS24285	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC88_RS24300	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC88_RS24310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC88_RS24315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC88_RS24320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC88_RS24340	COG0745	RESPONSE REGULATOR receiver
FOC88_RS24345	COG2205	protein histidine kinase activity
FOC88_RS24385	COG1215	transferase activity, transferring glycosyl groups
FOC88_RS24405	COG2226	methyltransferase
FOC88_RS24435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC88_RS24460	COG5002	protein histidine kinase activity
FOC88_RS24470	COG2252	PERMEase
FOC88_RS24490	COG1266	CAAX protease self-immunity
FOC88_RS24505	COG0488	(ABC) transporter
FOC88_RS24515	COG0456	acetyltransferase
FOC88_RS24520	COG1214	PFAM Peptidase M22, glycoprotease
FOC88_RS24525	COG0802	atpase or kinase
FOC88_RS24620	COG2183	response to ionizing radiation
FOC88_RS24625	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOC88_RS24630	COG0864	Transcriptional regulator
FOC88_RS24635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC88_RS24640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC88_RS24650	COG0705	Rhomboid family
FOC88_RS24650	COG0457	Tetratricopeptide repeat
FOC88_RS24655	COG4294	response to UV
FOC88_RS24665	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC88_RS24675	COG2814	Major facilitator Superfamily
FOC88_RS24685	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC88_RS24690	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FOC88_RS24720	COG0561	phosphatase activity
FOC88_RS24725	COG4608	Belongs to the ABC transporter superfamily
FOC88_RS24730	COG0444	Belongs to the ABC transporter superfamily
FOC88_RS24735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC88_RS24740	COG0601	transmembrane transport
FOC88_RS24745	COG0747	negative chemotaxis
FOC88_RS24755	COG0842	Transport permease protein
FOC88_RS24760	COG1511	domain protein
FOC88_RS24760	COG0842	Transport permease protein
FOC88_RS24765	COG1131	(ABC) transporter
FOC88_RS24770	COG2197	response regulator
FOC88_RS24775	COG4585	Histidine kinase
FOC88_RS24780	COG0488	(ABC) transporter
FOC88_RS24805	COG5298	Protein conserved in bacteria
FOC88_RS24810	COG0084	hydrolase, TatD family'
FOC88_RS24820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC88_RS24830	COG1609	Transcriptional regulator
FOC88_RS24840	COG0204	Acyl-transferase
FOC88_RS24855	COG0697	spore germination
FOC88_RS24870	COG1910	domain protein
FOC88_RS24875	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC88_RS24880	COG4149	molybdate abc transporter
FOC88_RS24895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC88_RS24900	COG0656	L-ascorbic acid biosynthetic process
FOC88_RS24905	COG4166	transmembrane transport
FOC88_RS24910	COG4166	transmembrane transport
FOC88_RS24925	COG2207	Transcriptional regulator
FOC88_RS24935	COG4166	transmembrane transport
FOC88_RS24940	COG4608	Belongs to the ABC transporter superfamily
FOC88_RS24945	COG0444	Belongs to the ABC transporter superfamily
FOC88_RS24950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC88_RS24955	COG0601	transmembrane transport
FOC88_RS24970	COG2814	Major facilitator Superfamily
FOC88_RS24980	COG2271	Major facilitator Superfamily
FOC88_RS24985	COG0277	FAD linked oxidase domain protein
FOC88_RS24995	COG0604	alcohol dehydrogenase
FOC88_RS25000	COG1464	Belongs to the NlpA lipoprotein family
FOC88_RS25005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC88_RS25010	COG2011	ABC-type metal ion transport system permease component
FOC88_RS25015	COG1028	Short-chain dehydrogenase reductase Sdr
FOC88_RS25050	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC88_RS25070	COG0596	Alpha beta hydrolase
FOC88_RS25090	COG4856	YbbR-like protein
FOC88_RS25095	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC88_RS25175	COG0726	polysaccharide deacetylase
FOC88_RS25180	COG2194	sulfuric ester hydrolase activity
FOC88_RS25190	COG0489	protein tyrosine kinase activity
FOC88_RS25195	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC88_RS25220	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC88_RS25255	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC88_RS25265	COG0024	Methionine aminopeptidase
FOC88_RS25275	COG0201	protein transport
FOC88_RS25335	COG0255	Belongs to the universal ribosomal protein uL29 family
FOC88_RS25405	COG1358	cellular component organization or biogenesis
FOC88_RS25420	COG2813	Specifically methylates the guanine in position
FOC88_RS25440	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOC88_RS25445	COG0250	Participates in transcription elongation, termination and antitermination
FOC88_RS25450	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC88_RS25465	COG3688	RNA-binding protein containing a PIN domain
FOC88_RS25470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC88_RS25485	COG1045	serine acetyltransferase
FOC88_RS25505	COG4956	integral membrane protein (PIN domain superfamily)
FOC88_RS25515	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC88_RS25520	COG0542	response to heat
FOC88_RS25530	COG3880	PFAM UvrB UvrC protein
FOC88_RS25620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC88_RS25625	COG1396	sequence-specific DNA binding
FOC88_RS25630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC88_RS25635	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC88_RS25640	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC88_RS25645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC88_RS25650	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC88_RS25655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC88_RS25660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC88_RS25675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC88_RS25690	COG2208	phosphoserine phosphatase activity
FOC88_RS25705	COG1098	S1 RNA binding domain
FOC88_RS25725	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC88_RS25730	COG3956	TIGRFAM MazG family protein
FOC88_RS25735	COG2244	polysaccharide biosynthetic process
FOC88_RS25740	COG2002	toxin-antitoxin pair type II binding
FOC88_RS25745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC88_RS25775	COG0251	oxidation-reduction process
FOC88_RS25780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC88_RS25795	COG4466	Protein conserved in bacteria
FOC88_RS25810	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC88_RS25815	COG0084	hydrolase, TatD family'
FOC88_RS25820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC88_RS25820	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC88_RS25825	COG2002	toxin-antitoxin pair type II binding
FOC88_RS25830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC88_RS25840	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC88_RS25850	COG1774	PSP1 C-terminal conserved region
FOC88_RS25855	COG0470	DNA polymerase III
FOC88_RS25865	COG1982	Orn Lys Arg decarboxylase major
FOC88_RS25920	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC88_RS25930	COG0590	tRNA wobble adenosine to inosine editing
FOC88_RS25935	COG1335	isochorismatase
FOC88_RS25940	COG1428	Deoxynucleoside kinase
FOC88_RS25945	COG1428	Deoxynucleoside kinase
FOC88_RS25975	COG1686	Belongs to the peptidase S11 family
FOC88_RS25980	COG0516	GMP reductase activity
FOC88_RS25980	COG0517	IMP dehydrogenase activity
FOC88_RS26015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC88_RS26020	COG0187	DNA topoisomerase II activity
FOC88_RS26030	COG2501	S4 domain
FOC88_RS26035	COG0592	DNA-directed DNA polymerase activity
FOC88_RS26045	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOC88_RS26055	COG0706	membrane insertase activity
FOC88_RS26060	COG1847	R3H domain protein
FOC88_RS26085	COG1192	Involved in chromosome partitioning
FOC88_RS26090	COG1475	DNA binding
FOC88_RS26100	COG0668	transmembrane transport
FOC88_RS26105	COG4481	Protein conserved in bacteria
FOC88_RS26110	COG0012	GTP binding
FOC88_RS26120	COG0629	single-stranded DNA binding
FOC88_RS26130	COG4241	membrane
FOC88_RS26135	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOC88_RS26145	COG0305	Participates in initiation and elongation during chromosome replication
FOC88_RS26175	COG0745	RESPONSE REGULATOR receiver
FOC88_RS26180	COG5002	protein histidine kinase activity
FOC88_RS26185	COG4863	YycH protein
FOC88_RS26190	COG4853	Protein conserved in bacteria
FOC88_RS26195	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC88_RS26200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC88_RS26220	COG1164	Oligoendopeptidase f
FOC88_RS26245	COG1272	protein, Hemolysin III
FOC88_RS26250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC88_RS26270	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC88_RS26275	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOC88_RS26280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC88_RS26285	COG2814	Major facilitator Superfamily
FOC88_RS26290	COG3275	phosphorelay sensor kinase activity
FOC88_RS26295	COG3279	Response regulator of the LytR AlgR family
FOC88_RS26310	COG0628	permease
FOC88_RS26315	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC88_RS26315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC88_RS26320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC88_RS26325	COG1309	transcriptional regulator
FOC88_RS26330	COG0463	Glycosyl transferase, family 2
FOC88_RS26350	COG0488	(ABC) transporter
FOC88_RS26365	COG1607	acyl-coa hydrolase
FOC88_RS26375	COG0840	transmembrane signaling receptor activity
FOC88_RS26400	COG0477	Major facilitator Superfamily
FOC88_RS26405	COG3279	Response regulator of the LytR AlgR family
FOC88_RS26410	COG1966	Carbon starvation protein
FOC88_RS26415	COG2879	small protein
FOC88_RS26420	COG3706	GGDEF domain
FOC88_RS26425	COG0351	phosphomethylpyrimidine kinase
FOC88_RS26430	COG4585	Histidine kinase
FOC88_RS26430	COG2203	Gaf domain
FOC88_RS26435	COG2197	response regulator
FOC88_RS26445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC88_RS26450	COG1011	Hydrolase
FOC88_RS26460	COG2873	o-acetylhomoserine
FOC88_RS26470	COG0460	homoserine dehydrogenase
FOC88_RS26480	COG1609	Transcriptional regulator
FOC88_RS26485	COG2755	lipolytic protein G-D-S-L family
FOC88_RS26490	COG1131	(ABC) transporter
FOC88_RS26495	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC88_RS26505	COG2814	Major facilitator Superfamily
FOC88_RS26510	COG0561	phosphatase activity
FOC88_RS26515	COG2233	PERMEase
FOC88_RS26520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC88_RS26530	COG2363	Small membrane protein
FOC88_RS26540	COG3773	Cell wall hydrolase
FOC88_RS26555	COG0280	phosphate acetyltransferase
FOC88_RS26560	COG0095	Lipoate-protein ligase
FOC88_RS26580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC88_RS26585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC88_RS26590	COG1120	ATPase activity
FOC88_RS26595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC88_RS26600	COG1078	dGTPase activity
FOC88_RS26610	COG1994	Peptidase M50
FOC88_RS26620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC88_RS26625	COG0584	glycerophosphoryl diester phosphodiesterase
FOC88_RS26630	COG0789	Transcriptional regulator
FOC88_RS26635	COG2814	Major facilitator Superfamily
FOC88_RS26645	COG0010	Belongs to the arginase family
FOC88_RS26660	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC88_RS26665	COG4506	Protein conserved in bacteria
FOC88_RS26675	COG1595	DNA-templated transcription, initiation
FOC88_RS26695	COG2234	aminopeptidase activity
FOC88_RS26705	COG0024	Methionine aminopeptidase
FOC88_RS26710	COG1131	(ABC) transporter
FOC88_RS26715	COG0842	Transport permease protein
FOC88_RS26720	COG4585	Histidine kinase
FOC88_RS26725	COG2197	response regulator
FOC88_RS26745	COG5001	Diguanylate cyclase
FOC88_RS26745	COG3300	MHYT domain
FOC88_RS26755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC88_RS26760	COG0247	lactate metabolic process
FOC88_RS26760	COG2181	nitrate reductase activity
FOC88_RS26765	COG0183	Belongs to the thiolase family
FOC88_RS26770	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC88_RS26775	COG1960	acyl-CoA dehydrogenase activity
FOC88_RS26780	COG1960	acyl-CoA dehydrogenase activity
FOC88_RS26800	COG4821	SIS domain
FOC88_RS26820	COG1494	fructose-1,6-bisphosphatase
FOC88_RS26825	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC88_RS26845	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC88_RS26860	COG0009	L-threonylcarbamoyladenylate synthase
FOC88_RS26875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC88_RS26880	COG2259	Doxx family
FOC88_RS26885	COG2190	(PTS) system
FOC88_RS26895	COG0698	ribose 5-phosphate isomerase
FOC88_RS26930	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC88_RS26980	COG3300	MHYT domain
FOC88_RS26980	COG5001	Diguanylate cyclase
FOC88_RS26995	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC88_RS27000	COG0649	NAD binding
FOC88_RS27015	COG0839	Belongs to the complex I subunit 6 family
FOC88_RS27025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC88_RS27030	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC88_RS27035	COG1007	ATP synthesis coupled electron transport
FOC88_RS27040	COG4836	Membrane
FOC88_RS27055	COG2385	sporulation resulting in formation of a cellular spore
FOC88_RS27060	COG3279	Response regulator of the LytR AlgR family
FOC88_RS27075	COG0739	heme binding
FOC88_RS27090	COG0726	polysaccharide deacetylase
FOC88_RS27095	COG1609	Transcriptional regulator
FOC88_RS27115	COG1216	Glycosyl transferase, family 2
FOC88_RS27115	COG1442	glycosyl transferase family 8
FOC88_RS27125	COG1215	transferase activity, transferring glycosyl groups
FOC88_RS27125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOC88_RS27135	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC88_RS27140	COG1682	transport, permease protein
FOC88_RS27145	COG1134	teichoic acid transport
FOC88_RS27150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC88_RS27170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC88_RS27175	COG0745	RESPONSE REGULATOR receiver
FOC88_RS27180	COG5002	protein histidine kinase activity
FOC88_RS27205	COG1136	(ABC) transporter
FOC88_RS27210	COG0577	efflux transmembrane transporter activity
FOC88_RS27250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC88_RS27255	COG4715	Zinc finger, swim domain protein
FOC88_RS27280	COG1388	LysM domain
FOC88_RS27280	COG3584	3D domain protein
FOC88_RS27285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC88_RS27290	COG1215	transferase activity, transferring glycosyl groups
FOC88_RS27300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC88_RS27305	COG0791	NLP P60 protein
FOC88_RS27305	COG1388	LysM domain
FOC88_RS27380	COG1484	DNA-dependent DNA replication
FOC88_RS27430	COG1396	sequence-specific DNA binding
FOC88_RS27510	COG1192	Involved in chromosome partitioning
FOC88_RS27530	COG2329	Antibiotic biosynthesis monooxygenase
FOC88_RS27555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC88_RS27655	COG4653	Phage capsid family
FOC88_RS27660	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FOC88_RS27665	COG2369	cell adhesion
FOC88_RS27670	COG5518	Phage portal protein
FOC88_RS27690	COG5484	DNA packaging