locus-tag	class	description
FOC89_RS00065	COG1396	sequence-specific DNA binding
FOC89_RS00115	COG1484	DNA-dependent DNA replication
FOC89_RS00150	COG0756	dUTP diphosphatase activity
FOC89_RS00200	COG5484	DNA packaging
FOC89_RS00210	COG5518	Phage portal protein
FOC89_RS00215	COG2369	cell adhesion
FOC89_RS00220	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FOC89_RS00225	COG4653	Phage capsid family
FOC89_RS00300	COG4824	toxin secretion phage lysis holin
FOC89_RS00315	COG5444	nuclease activity
FOC89_RS00325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC89_RS00350	COG2329	Antibiotic biosynthesis monooxygenase
FOC89_RS00370	COG1192	Involved in chromosome partitioning
FOC89_RS00390	COG3012	SEC-C Motif Domain Protein
FOC89_RS00390	COG1405	negative regulation of cell septum assembly
FOC89_RS00405	COG3104	oligopeptide transport
FOC89_RS00450	COG0842	Transport permease protein
FOC89_RS00455	COG1131	(ABC) transporter
FOC89_RS00510	COG4974	Belongs to the 'phage' integrase family
FOC89_RS00550	COG0551	DNA topoisomerase type I activity
FOC89_RS00550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC89_RS00630	COG0791	NLP P60 protein
FOC89_RS00630	COG0741	lytic transglycosylase activity
FOC89_RS00805	COG1192	Involved in chromosome partitioning
FOC89_RS00830	COG4166	transmembrane transport
FOC89_RS00870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC89_RS00915	COG0210	DNA helicase
FOC89_RS01190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC89_RS01190	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC89_RS01210	COG3764	Sortase (surface protein transpeptidase)
FOC89_RS01340	COG4990	cell redox homeostasis
FOC89_RS01480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC89_RS01750	COG0187	DNA topoisomerase II activity
FOC89_RS01755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC89_RS01820	COG0358	DNA primase activity
FOC89_RS02030	COG1876	peptidase activity
FOC89_RS02185	COG5263	repeat protein
FOC89_RS02185	COG4193	domain, Protein
FOC89_RS02320	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC89_RS02320	COG3409	Peptidoglycan-binding domain 1 protein
FOC89_RS02325	COG3409	Peptidoglycan-binding domain 1 protein
FOC89_RS02325	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC89_RS02480	COG3091	SprT-like family
FOC89_RS02565	COG3481	metal-dependent phosphohydrolase, HD sub domain
FOC89_RS02640	COG2815	serine threonine protein kinase
FOC89_RS02640	COG0515	serine threonine protein kinase
FOC89_RS03060	COG0484	heat shock protein binding
FOC89_RS03150	COG1288	antiporter activity
FOC89_RS03165	COG2814	Major facilitator Superfamily
FOC89_RS03170	COG1309	transcriptional regulator
FOC89_RS03180	COG3620	sequence-specific DNA binding
FOC89_RS03185	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC89_RS03205	COG1733	regulation of RNA biosynthetic process
FOC89_RS03210	COG0778	Nitroreductase
FOC89_RS03230	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS03240	COG1131	(ABC) transporter
FOC89_RS03265	COG1011	Hydrolase
FOC89_RS03300	COG0346	lactoylglutathione lyase activity
FOC89_RS03305	COG1940	carbohydrate kinase activity
FOC89_RS03310	COG0738	Major facilitator superfamily
FOC89_RS03315	COG0110	maltose O-acetyltransferase activity
FOC89_RS03325	COG0577	efflux transmembrane transporter activity
FOC89_RS03325	COG1136	(ABC) transporter
FOC89_RS03345	COG0628	permease
FOC89_RS03365	COG2226	methyltransferase
FOC89_RS03375	COG0477	Major facilitator Superfamily
FOC89_RS03405	COG1253	flavin adenine dinucleotide binding
FOC89_RS03410	COG0789	Transcriptional regulator
FOC89_RS03415	COG0697	spore germination
FOC89_RS03420	COG1357	PFAM Pentapeptide repeats (8 copies)
FOC89_RS03425	COG3813	Protein conserved in bacteria
FOC89_RS03430	COG2706	6-phosphogluconolactonase activity
FOC89_RS03435	COG1070	Carbohydrate kinase
FOC89_RS03445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC89_RS03450	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOC89_RS03460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC89_RS03475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC89_RS03495	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS03535	COG0814	amino acid
FOC89_RS03560	COG1393	Belongs to the ArsC family
FOC89_RS03565	COG1733	regulation of RNA biosynthetic process
FOC89_RS03570	COG2188	Transcriptional regulator
FOC89_RS03575	COG0673	inositol 2-dehydrogenase activity
FOC89_RS03580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC89_RS03585	COG1733	regulation of RNA biosynthetic process
FOC89_RS03590	COG1733	regulation of RNA biosynthetic process
FOC89_RS03610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC89_RS03630	COG0384	phenazine biosynthesis protein PhzF
FOC89_RS03640	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS03650	COG0318	PFAM AMP-dependent synthetase and ligase
FOC89_RS03655	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC89_RS03660	COG1733	regulation of RNA biosynthetic process
FOC89_RS03680	COG1191	sigma factor activity
FOC89_RS03695	COG1309	transcriptional regulator
FOC89_RS03715	COG3152	Membrane
FOC89_RS03740	COG1151	hydroxylamine reductase activity
FOC89_RS03750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC89_RS03790	COG2072	flavoprotein involved in K transport
FOC89_RS03825	COG0604	alcohol dehydrogenase
FOC89_RS03830	COG1113	amino acid transport
FOC89_RS03835	COG2814	Major facilitator Superfamily
FOC89_RS03865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC89_RS03870	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC89_RS03885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC89_RS03890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC89_RS03895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC89_RS03900	COG3739	integral membrane protein
FOC89_RS03905	COG0384	phenazine biosynthesis protein PhzF
FOC89_RS03935	COG0583	DNA-binding transcription factor activity
FOC89_RS03955	COG1193	negative regulation of DNA recombination
FOC89_RS03970	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FOC89_RS03975	COG1164	Oligoendopeptidase f
FOC89_RS03980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC89_RS04010	COG0584	glycerophosphoryl diester phosphodiesterase
FOC89_RS04035	COG0640	Transcriptional regulator
FOC89_RS04040	COG0604	alcohol dehydrogenase
FOC89_RS04085	COG2808	Putative FMN-binding domain
FOC89_RS04090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC89_RS04100	COG0385	Bile acid
FOC89_RS04105	COG0277	FAD linked oxidase domain protein
FOC89_RS04135	COG1216	Glycosyl transferase, family 2
FOC89_RS04140	COG1024	Enoyl-CoA hydratase
FOC89_RS04150	COG1285	pathogenesis
FOC89_RS04165	COG2514	catechol 2,3-dioxygenase activity
FOC89_RS04170	COG2720	vancomycin resistance protein
FOC89_RS04210	COG0716	FMN binding
FOC89_RS04260	COG0739	heme binding
FOC89_RS04275	COG3757	hydrolase, family 25
FOC89_RS04275	COG3409	Peptidoglycan-binding domain 1 protein
FOC89_RS04280	COG0739	heme binding
FOC89_RS04335	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS04345	COG0165	Argininosuccinate lyase
FOC89_RS04360	COG4145	pantothenate transmembrane transporter activity
FOC89_RS04370	COG1012	belongs to the aldehyde dehydrogenase family
FOC89_RS04375	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS04385	COG1657	PFAM Prenyltransferase squalene oxidase
FOC89_RS04390	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOC89_RS04395	COG2962	Rard protein
FOC89_RS04400	COG3326	Membrane
FOC89_RS04415	COG0489	protein tyrosine kinase activity
FOC89_RS04425	COG0314	molybdopterin synthase activity
FOC89_RS04430	COG0303	'Molybdopterin
FOC89_RS04435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC89_RS04440	COG2116	formate transmembrane transporter activity
FOC89_RS04450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC89_RS04455	COG5609	conserved protein (DUF2294)
FOC89_RS04460	COG2427	Protein of unknown function (DUF1641)
FOC89_RS04465	COG3383	formate dehydrogenase (NAD+) activity
FOC89_RS04475	COG0697	spore germination
FOC89_RS04515	COG2226	methyltransferase
FOC89_RS04520	COG4166	transmembrane transport
FOC89_RS04530	COG4166	transmembrane transport
FOC89_RS04535	COG4166	transmembrane transport
FOC89_RS04540	COG1301	dicarboxylic acid transport
FOC89_RS04545	COG1316	TRANSCRIPTIONal
FOC89_RS04555	COG1595	DNA-templated transcription, initiation
FOC89_RS04575	COG1131	(ABC) transporter
FOC89_RS04585	COG0673	inositol 2-dehydrogenase activity
FOC89_RS04590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC89_RS04595	COG0187	DNA topoisomerase II activity
FOC89_RS04600	COG1832	CoA-binding protein
FOC89_RS04605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC89_RS04610	COG0745	RESPONSE REGULATOR receiver
FOC89_RS04630	COG4841	protein insertion into membrane
FOC89_RS04635	COG0824	Thioesterase
FOC89_RS04665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC89_RS04675	COG2274	protein secretion by the type I secretion system
FOC89_RS04680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC89_RS04720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC89_RS04735	COG0183	Belongs to the thiolase family
FOC89_RS04740	COG0318	PFAM AMP-dependent synthetase and ligase
FOC89_RS04745	COG1268	BioY protein
FOC89_RS04750	COG0318	PFAM AMP-dependent synthetase and ligase
FOC89_RS04800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC89_RS04810	COG5002	protein histidine kinase activity
FOC89_RS04815	COG0400	carboxylic ester hydrolase activity
FOC89_RS04820	COG0346	lactoylglutathione lyase activity
FOC89_RS04825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC89_RS04830	COG0069	glutamate synthase activity
FOC89_RS04835	COG1902	pentaerythritol trinitrate reductase activity
FOC89_RS04840	COG1329	Transcriptional regulator
FOC89_RS04845	COG0010	Belongs to the arginase family
FOC89_RS04905	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC89_RS04910	COG0785	Cytochrome C biogenesis protein
FOC89_RS04920	COG1473	amidohydrolase
FOC89_RS04930	COG1131	(ABC) transporter
FOC89_RS04940	COG0583	DNA-binding transcription factor activity
FOC89_RS04950	COG1346	cytolysis
FOC89_RS04965	COG0730	response to heat
FOC89_RS04975	COG3409	Peptidoglycan-binding domain 1 protein
FOC89_RS04975	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC89_RS04990	COG1132	(ABC) transporter
FOC89_RS04995	COG1132	(ABC) transporter
FOC89_RS05025	COG3639	organic phosphonate transmembrane transporter activity
FOC89_RS05030	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC89_RS05035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC89_RS05040	COG0737	Belongs to the 5'-nucleotidase family
FOC89_RS05050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC89_RS05070	COG1695	Transcriptional regulator
FOC89_RS05085	COG5444	nuclease activity
FOC89_RS05100	COG0174	glutamine synthetase
FOC89_RS05105	COG0789	Transcriptional regulator
FOC89_RS05110	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOC89_RS05115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC89_RS05120	COG2860	membrane
FOC89_RS05125	COG0464	growth
FOC89_RS05155	COG3584	3D domain protein
FOC89_RS05155	COG1388	LysM domain
FOC89_RS05160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC89_RS05160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC89_RS05160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC89_RS05165	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC89_RS05170	COG1349	DNA-binding transcription factor activity
FOC89_RS05175	COG1979	alcohol dehydrogenase
FOC89_RS05180	COG2322	membrane
FOC89_RS05190	COG1113	amino acid transport
FOC89_RS05205	COG1408	metallophosphoesterase
FOC89_RS05210	COG2116	formate transmembrane transporter activity
FOC89_RS05225	COG2217	Heavy metal translocating P-type atpase
FOC89_RS05230	COG2608	mercury ion transmembrane transporter activity
FOC89_RS05235	COG1937	Protein conserved in bacteria
FOC89_RS05245	COG2819	hydrolase of the alpha beta superfamily
FOC89_RS05250	COG1120	ATPase activity
FOC89_RS05255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC89_RS05260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC89_RS05265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC89_RS05270	COG0708	Exodeoxyribonuclease III
FOC89_RS05275	COG2169	Transcriptional regulator
FOC89_RS05280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC89_RS05285	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC89_RS05295	COG2364	Membrane
FOC89_RS05310	COG2267	carboxylic ester hydrolase activity
FOC89_RS05315	COG0346	lactoylglutathione lyase activity
FOC89_RS05320	COG5001	Diguanylate cyclase
FOC89_RS05320	COG3300	MHYT domain
FOC89_RS05335	COG1346	cytolysis
FOC89_RS05340	COG1380	Effector of murein hydrolase LrgA
FOC89_RS05345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC89_RS05355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC89_RS05375	COG1404	Belongs to the peptidase S8 family
FOC89_RS05380	COG3773	Cell wall hydrolase
FOC89_RS05385	COG0562	UDP-galactopyranose mutase
FOC89_RS05390	COG1368	sulfuric ester hydrolase activity
FOC89_RS05395	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC89_RS05405	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOC89_RS05425	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOC89_RS05435	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC89_RS05440	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC89_RS05440	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC89_RS05450	COG2359	stage V sporulation protein S
FOC89_RS05455	COG1692	metallophosphoesterase
FOC89_RS05480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC89_RS05485	COG1426	Protein conserved in bacteria
FOC89_RS05500	COG0300	oxidoreductase activity
FOC89_RS05505	COG0612	Peptidase, M16
FOC89_RS05510	COG0612	Peptidase, M16
FOC89_RS05535	COG2188	Transcriptional regulator
FOC89_RS05540	COG1674	ftsk spoiiie
FOC89_RS05550	COG0740	serine-type endopeptidase activity
FOC89_RS05555	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC89_RS05565	COG0527	aspartate kinase activity
FOC89_RS05570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC89_RS05575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC89_RS05580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC89_RS05585	COG1873	PFAM PRC-barrel domain
FOC89_RS05590	COG0612	Peptidase, M16
FOC89_RS05595	COG0726	polysaccharide deacetylase
FOC89_RS05610	COG0196	riboflavin kinase activity
FOC89_RS05615	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC89_RS05625	COG1550	Protein conserved in bacteria
FOC89_RS05635	COG1358	cellular component organization or biogenesis
FOC89_RS05640	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOC89_RS05645	COG0195	Participates in both transcription termination and antitermination
FOC89_RS05665	COG0750	zinc metalloprotease
FOC89_RS05675	COG4589	Belongs to the CDS family
FOC89_RS05690	COG0528	UMP kinase activity
FOC89_RS05720	COG4974	Belongs to the 'phage' integrase family
FOC89_RS05730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC89_RS05735	COG0758	DNA mediated transformation
FOC89_RS05740	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC89_RS05780	COG1837	Belongs to the UPF0109 family
FOC89_RS05790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC89_RS05800	COG0552	protein localization to endoplasmic reticulum
FOC89_RS05805	COG1196	nuclear chromosome segregation
FOC89_RS05815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC89_RS05820	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS05825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC89_RS05840	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC89_RS05845	COG1461	Dihydroxyacetone kinase
FOC89_RS05850	COG1302	Protein conserved in bacteria
FOC89_RS05865	COG1564	THIamine pyrophosphokinase
FOC89_RS05870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC89_RS05875	COG1162	GTPase activity
FOC89_RS05880	COG0515	serine threonine protein kinase
FOC89_RS05880	COG2815	serine threonine protein kinase
FOC89_RS05885	COG0631	protein serine/threonine phosphatase activity
FOC89_RS05895	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC89_RS05895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC89_RS05905	COG0242	peptide deformylase activity
FOC89_RS05910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC89_RS05915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC89_RS05935	COG1561	YicC-like family, N-terminal region
FOC89_RS05940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC89_RS05950	COG0006	proline dipeptidase activity
FOC89_RS05970	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC89_RS06035	COG0564	pseudouridine synthase activity
FOC89_RS06055	COG3599	regulation of cell shape
FOC89_RS06060	COG2302	S4 RNA-binding domain
FOC89_RS06065	COG0762	integral membrane protein
FOC89_RS06075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC89_RS06085	COG1873	PFAM PRC-barrel domain
FOC89_RS06090	COG1191	sigma factor activity
FOC89_RS06095	COG1191	sigma factor activity
FOC89_RS06105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC89_RS06110	COG0849	cell division
FOC89_RS06115	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC89_RS06120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC89_RS06130	COG0772	Belongs to the SEDS family
FOC89_RS06145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC89_RS06150	COG0768	penicillin binding
FOC89_RS06160	COG4839	cell division protein FtsL
FOC89_RS06175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC89_RS06190	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOC89_RS06195	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC89_RS06205	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOC89_RS06210	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC89_RS06215	COG3314	Sporulation integral membrane protein YlbJ
FOC89_RS06225	COG0742	ribosomal rna small subunit methyltransferase
FOC89_RS06240	COG3679	Belongs to the UPF0342 family
FOC89_RS06245	COG0406	alpha-ribazole phosphatase activity
FOC89_RS06260	COG2340	Cysteine-rich secretory protein family
FOC89_RS06275	COG3336	cytochrome c oxidase
FOC89_RS06310	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOC89_RS06315	COG0772	Belongs to the SEDS family
FOC89_RS06325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC89_RS06330	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC89_RS06340	COG4896	Protein conserved in bacteria
FOC89_RS06365	COG0483	inositol monophosphate 1-phosphatase activity
FOC89_RS06385	COG1982	Orn Lys Arg decarboxylase major
FOC89_RS06435	COG0022	dehydrogenase e1 component
FOC89_RS06440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC89_RS06450	COG0242	peptide deformylase activity
FOC89_RS06455	COG0561	phosphatase activity
FOC89_RS06465	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC89_RS06470	COG0569	domain protein
FOC89_RS06490	COG0583	DNA-binding transcription factor activity
FOC89_RS06495	COG0517	IMP dehydrogenase activity
FOC89_RS06505	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOC89_RS06515	COG4703	Protein of unknown function (DUF1797)
FOC89_RS06530	COG2200	EAL domain
FOC89_RS06535	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS06540	COG1408	metallophosphoesterase
FOC89_RS06550	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC89_RS06585	COG2814	Major facilitator Superfamily
FOC89_RS06605	COG3209	COG3209 Rhs family protein
FOC89_RS06615	COG2205	protein histidine kinase activity
FOC89_RS06625	COG0436	Aminotransferase
FOC89_RS06630	COG1609	Transcriptional regulator
FOC89_RS06635	COG3833	ABC-type maltose transport systems, permease component
FOC89_RS06640	COG1175	transmembrane transport
FOC89_RS06645	COG2182	Extracellular solute-binding protein
FOC89_RS06655	COG0366	Alpha amylase catalytic
FOC89_RS06660	COG3842	ATPase activity
FOC89_RS06700	COG0183	Belongs to the thiolase family
FOC89_RS06735	COG1695	Transcriptional regulator
FOC89_RS06740	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS06760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC89_RS06765	COG0436	Aminotransferase
FOC89_RS06800	COG2084	Dehydrogenase
FOC89_RS06805	COG3706	GGDEF domain
FOC89_RS06810	COG0778	Nitroreductase
FOC89_RS06835	COG1263	PTS System
FOC89_RS06835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC89_RS06835	COG2190	(PTS) system
FOC89_RS06840	COG3711	transcriptional antiterminator
FOC89_RS06850	COG2188	Transcriptional regulator
FOC89_RS06860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC89_RS06885	COG1547	Domain of unknown function (DUF309)
FOC89_RS06890	COG0456	acetyltransferase
FOC89_RS06895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC89_RS06900	COG4086	secreted protein
FOC89_RS06905	COG0561	phosphatase activity
FOC89_RS06910	COG0697	spore germination
FOC89_RS06925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC89_RS06950	COG0733	neurotransmitter:sodium symporter activity
FOC89_RS06970	COG1686	Belongs to the peptidase S11 family
FOC89_RS06975	COG1725	Transcriptional regulator
FOC89_RS06980	COG1131	(ABC) transporter
FOC89_RS07000	COG1846	Transcriptional regulator
FOC89_RS07015	COG0598	Magnesium transport protein CorA
FOC89_RS07040	COG4974	Belongs to the 'phage' integrase family
FOC89_RS07050	COG0735	belongs to the Fur family
FOC89_RS07055	COG1300	Membrane
FOC89_RS07075	COG0667	Aldo Keto reductase
FOC89_RS07080	COG0656	L-ascorbic acid biosynthetic process
FOC89_RS07085	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC89_RS07085	COG0456	acetyltransferase
FOC89_RS07095	COG1525	nuclease
FOC89_RS07095	COG0737	Belongs to the 5'-nucleotidase family
FOC89_RS07095	COG4085	toxin activity
FOC89_RS07105	COG0596	Alpha beta hydrolase
FOC89_RS07110	COG2056	Na+-H+ antiporter family
FOC89_RS07115	COG1609	Transcriptional regulator
FOC89_RS07120	COG0456	acetyltransferase
FOC89_RS07125	COG1073	alpha beta
FOC89_RS07140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC89_RS07140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC89_RS07145	COG0307	riboflavin synthase, alpha
FOC89_RS07170	COG4106	trans-aconitate 2-methyltransferase activity
FOC89_RS07175	COG1073	alpha beta
FOC89_RS07175	COG2226	methyltransferase
FOC89_RS07190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC89_RS07205	COG0737	Belongs to the 5'-nucleotidase family
FOC89_RS07215	COG1522	sequence-specific DNA binding
FOC89_RS07235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC89_RS07245	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOC89_RS07260	COG0300	oxidoreductase activity
FOC89_RS07265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC89_RS07270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC89_RS07275	COG1760	l-serine dehydratase
FOC89_RS07280	COG1760	l-serine dehydratase
FOC89_RS07300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC89_RS07310	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC89_RS07315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC89_RS07330	COG1376	ErfK ybiS ycfS ynhG family protein
FOC89_RS07335	COG4129	membrane
FOC89_RS07340	COG1126	abc transporter atp-binding protein
FOC89_RS07345	COG0765	amino acid transport
FOC89_RS07350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC89_RS07365	COG2816	NAD+ diphosphatase activity
FOC89_RS07370	COG0772	Belongs to the SEDS family
FOC89_RS07375	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC89_RS07380	COG0022	dehydrogenase e1 component
FOC89_RS07385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC89_RS07390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC89_RS07405	COG0280	phosphate acetyltransferase
FOC89_RS07410	COG3290	protein histidine kinase activity
FOC89_RS07410	COG3829	transcription factor binding
FOC89_RS07420	COG0584	glycerophosphoryl diester phosphodiesterase
FOC89_RS07425	COG3093	addiction module antidote protein HigA
FOC89_RS07435	COG0745	RESPONSE REGULATOR receiver
FOC89_RS07440	COG0750	zinc metalloprotease
FOC89_RS07445	COG0497	DNA recombination
FOC89_RS07455	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOC89_RS07465	COG0142	geranyltranstransferase activity
FOC89_RS07490	COG1302	Protein conserved in bacteria
FOC89_RS07495	COG0439	Biotin carboxylase
FOC89_RS07500	COG0511	ligase activity, forming carbon-carbon bonds
FOC89_RS07545	COG3854	ATPases associated with a variety of cellular activities
FOC89_RS07570	COG0006	proline dipeptidase activity
FOC89_RS07585	COG3872	metal-dependent enzyme
FOC89_RS07595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC89_RS07615	COG0095	Lipoate-protein ligase
FOC89_RS07620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC89_RS07625	COG1609	Transcriptional regulator
FOC89_RS07635	COG2076	Multidrug Resistance protein
FOC89_RS07640	COG2076	Multidrug Resistance protein
FOC89_RS07675	COG1131	(ABC) transporter
FOC89_RS07680	COG1725	Transcriptional regulator
FOC89_RS07710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC89_RS07765	COG4970	Tfp pilus assembly protein FimT
FOC89_RS07775	COG1459	type II secretion system
FOC89_RS07780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC89_RS07830	COG1410	methionine synthase
FOC89_RS07830	COG0646	methionine synthase
FOC89_RS07835	COG0646	methionine synthase
FOC89_RS07835	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC89_RS07840	COG0626	cystathionine gamma-synthase activity
FOC89_RS07845	COG0626	cystathionine gamma-synthase activity
FOC89_RS07865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC89_RS07875	COG1940	carbohydrate kinase activity
FOC89_RS07880	COG4483	Protein conserved in bacteria
FOC89_RS07885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC89_RS07890	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC89_RS07895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC89_RS07900	COG0704	Plays a role in the regulation of phosphate uptake
FOC89_RS07910	COG0581	inorganic phosphate transmembrane transporter activity
FOC89_RS07915	COG0573	inorganic phosphate transmembrane transporter activity
FOC89_RS07920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC89_RS07930	COG0477	Major facilitator Superfamily
FOC89_RS07935	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC89_RS07960	COG0735	belongs to the Fur family
FOC89_RS07965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC89_RS07970	COG1121	(ABC) transporter
FOC89_RS07975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC89_RS08005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC89_RS08010	COG2384	SAM-dependent methyltransferase
FOC89_RS08015	COG2010	Cytochrome c
FOC89_RS08020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC89_RS08025	COG0358	DNA primase activity
FOC89_RS08040	COG0517	IMP dehydrogenase activity
FOC89_RS08055	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC89_RS08060	COG0295	cytidine deaminase activity
FOC89_RS08065	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC89_RS08075	COG1480	7TM receptor with intracellular HD hydrolase
FOC89_RS08080	COG1702	phosphate starvation-inducible protein PhoH
FOC89_RS08095	COG1610	YqeY-like protein
FOC89_RS08100	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOC89_RS08105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC89_RS08110	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC89_RS08140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC89_RS08145	COG1733	regulation of RNA biosynthetic process
FOC89_RS08170	COG1466	dna polymerase III delta subunit
FOC89_RS08180	COG2333	competence protein COMEC
FOC89_RS08180	COG0658	competence protein
FOC89_RS08185	COG2131	deaminase
FOC89_RS08190	COG1555	photosystem II stabilization
FOC89_RS08190	COG1596	polysaccharide export
FOC89_RS08195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC89_RS08200	COG2226	methyltransferase
FOC89_RS08205	COG0799	negative regulation of ribosome biogenesis
FOC89_RS08210	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOC89_RS08220	COG1534	Rna-binding protein
FOC89_RS08230	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC89_RS08235	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOC89_RS08260	COG1595	DNA-templated transcription, initiation
FOC89_RS08270	COG0778	Nitroreductase
FOC89_RS08275	COG2357	RelA SpoT domain protein
FOC89_RS08285	COG1785	Belongs to the alkaline phosphatase family
FOC89_RS08295	COG2267	carboxylic ester hydrolase activity
FOC89_RS08330	COG1404	Belongs to the peptidase S8 family
FOC89_RS08335	COG3186	Phenylalanine-4-hydroxylase
FOC89_RS08345	COG2514	catechol 2,3-dioxygenase activity
FOC89_RS08350	COG2259	Doxx family
FOC89_RS08390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC89_RS08400	COG1454	alcohol dehydrogenase
FOC89_RS08400	COG1012	belongs to the aldehyde dehydrogenase family
FOC89_RS08405	COG0626	cystathionine gamma-synthase activity
FOC89_RS08410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC89_RS08435	COG0768	penicillin binding
FOC89_RS08460	COG4122	O-methyltransferase activity
FOC89_RS08465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC89_RS08495	COG0628	permease
FOC89_RS08515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC89_RS08530	COG1104	cysteine desulfurase activity
FOC89_RS08535	COG1959	2 iron, 2 sulfur cluster binding
FOC89_RS08540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC89_RS08550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC89_RS08580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC89_RS08590	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC89_RS08590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC89_RS08595	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC89_RS08600	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC89_RS08600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC89_RS08610	COG2244	polysaccharide biosynthetic process
FOC89_RS08615	COG2323	membrane
FOC89_RS08625	COG1862	Preprotein translocase
FOC89_RS08655	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOC89_RS08685	COG0157	Belongs to the NadC ModD family
FOC89_RS08690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC89_RS08695	COG1104	cysteine desulfurase activity
FOC89_RS08700	COG1827	regulation of RNA biosynthetic process
FOC89_RS08705	COG2258	MOSC domain
FOC89_RS08710	COG0077	Prephenate dehydratase
FOC89_RS08715	COG0577	efflux transmembrane transporter activity
FOC89_RS08720	COG0577	efflux transmembrane transporter activity
FOC89_RS08725	COG1136	(ABC) transporter
FOC89_RS08730	COG5002	protein histidine kinase activity
FOC89_RS08735	COG0745	RESPONSE REGULATOR receiver
FOC89_RS08745	COG3290	protein histidine kinase activity
FOC89_RS08755	COG2868	ribosomal protein
FOC89_RS08765	COG1530	ribonuclease E activity
FOC89_RS08770	COG1994	Peptidase M50
FOC89_RS08775	COG0739	heme binding
FOC89_RS08780	COG2894	cell division
FOC89_RS08800	COG1077	Cell shape determining protein MreB Mrl
FOC89_RS08820	COG0285	dihydrofolate synthase activity
FOC89_RS08825	COG0525	valine-tRNA ligase activity
FOC89_RS08835	COG1388	LysM domain
FOC89_RS08845	COG0113	porphobilinogen synthase activity
FOC89_RS08850	COG1587	Uroporphyrinogen-III synthase
FOC89_RS08860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC89_RS08870	COG1846	Transcriptional regulator
FOC89_RS08875	COG1764	response to oxidative stress
FOC89_RS08890	COG0470	DNA polymerase III
FOC89_RS08890	COG1067	ATP-dependent peptidase activity
FOC89_RS08940	COG0622	Phosphoesterase
FOC89_RS08955	COG5401	PFAM Sporulation and spore germination
FOC89_RS08975	COG1309	transcriptional regulator
FOC89_RS08990	COG2197	response regulator
FOC89_RS08995	COG2233	PERMEase
FOC89_RS09005	COG0402	S-adenosylhomocysteine deaminase activity
FOC89_RS09010	COG0402	S-adenosylhomocysteine deaminase activity
FOC89_RS09030	COG0444	Belongs to the ABC transporter superfamily
FOC89_RS09035	COG4608	Belongs to the ABC transporter superfamily
FOC89_RS09040	COG3275	phosphorelay sensor kinase activity
FOC89_RS09045	COG3279	Response regulator of the LytR AlgR family
FOC89_RS09055	COG1983	PspC domain protein
FOC89_RS09060	COG1396	sequence-specific DNA binding
FOC89_RS09065	COG0697	spore germination
FOC89_RS09075	COG1959	2 iron, 2 sulfur cluster binding
FOC89_RS09080	COG1668	transmembrane transport
FOC89_RS09085	COG4152	abc transporter atp-binding protein
FOC89_RS09090	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOC89_RS09095	COG1360	Flagellar Motor Protein
FOC89_RS09100	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC89_RS09105	COG1876	peptidase activity
FOC89_RS09110	COG0824	Thioesterase
FOC89_RS09115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC89_RS09120	COG1053	succinate dehydrogenase
FOC89_RS09125	COG2009	succinate dehydrogenase
FOC89_RS09130	COG1719	4-vinyl reductase, 4VR
FOC89_RS09140	COG3118	belongs to the thioredoxin family
FOC89_RS09145	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC89_RS09150	COG2086	electron transfer activity
FOC89_RS09155	COG1024	Enoyl-CoA hydratase
FOC89_RS09160	COG1309	transcriptional regulator
FOC89_RS09165	COG0318	PFAM AMP-dependent synthetase and ligase
FOC89_RS09185	COG2318	DinB family
FOC89_RS09210	COG1131	(ABC) transporter
FOC89_RS09215	COG2205	protein histidine kinase activity
FOC89_RS09220	COG0745	RESPONSE REGULATOR receiver
FOC89_RS09230	COG4895	conserved protein (DUF2196)
FOC89_RS09235	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC89_RS09250	COG4509	Sortase family
FOC89_RS09255	COG1120	ATPase activity
FOC89_RS09270	COG5386	Cell surface protein
FOC89_RS09280	COG5386	Cell surface protein
FOC89_RS09285	COG1114	Component of the transport system for branched-chain amino acids
FOC89_RS09290	COG1187	pseudouridine synthase activity
FOC89_RS09300	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC89_RS09300	COG1796	DNA polymerase
FOC89_RS09305	COG1286	toxin biosynthetic process
FOC89_RS09350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC89_RS09360	COG1418	mRNA catabolic process
FOC89_RS09385	COG2814	Major facilitator Superfamily
FOC89_RS09390	COG1566	PFAM secretion protein HlyD family protein
FOC89_RS09395	COG1309	transcriptional regulator
FOC89_RS09400	COG1363	Peptidase, m42
FOC89_RS09425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC89_RS09435	COG1484	DNA-dependent DNA replication
FOC89_RS09440	COG3611	Membrane attachment protein
FOC89_RS09450	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC89_RS09455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC89_RS09460	COG0237	dephospho-CoA kinase activity
FOC89_RS09465	COG1971	Probably functions as a manganese efflux pump
FOC89_RS09475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC89_RS09475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC89_RS09480	COG5002	protein histidine kinase activity
FOC89_RS09485	COG0745	RESPONSE REGULATOR receiver
FOC89_RS09505	COG0538	isocitrate dehydrogenase activity
FOC89_RS09510	COG0372	Belongs to the citrate synthase family
FOC89_RS09520	COG0628	permease
FOC89_RS09525	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOC89_RS09550	COG1725	Transcriptional regulator
FOC89_RS09555	COG0281	malic enzyme
FOC89_RS09560	COG0587	DNA-directed DNA polymerase activity
FOC89_RS09575	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC89_RS09595	COG4109	DRTGG domain
FOC89_RS09610	COG0006	proline dipeptidase activity
FOC89_RS09660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC89_RS09665	COG0662	Cupin 2, conserved barrel domain protein
FOC89_RS09675	COG1476	TRANSCRIPTIONal
FOC89_RS09690	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS09695	COG0589	response to stress
FOC89_RS09735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC89_RS09760	COG0827	DNA restriction-modification system
FOC89_RS09765	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC89_RS09770	COG3874	Sporulation protein YtfJ
FOC89_RS09785	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC89_RS09795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC89_RS09810	COG1104	cysteine desulfurase activity
FOC89_RS09820	COG0583	DNA-binding transcription factor activity
FOC89_RS09825	COG0697	spore germination
FOC89_RS09830	COG1309	transcriptional regulator
FOC89_RS09835	COG1956	GAF domain-containing protein
FOC89_RS09840	COG0626	cystathionine gamma-synthase activity
FOC89_RS09870	COG1595	DNA-templated transcription, initiation
FOC89_RS09880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC89_RS09885	COG0454	-acetyltransferase
FOC89_RS09890	COG0517	IMP dehydrogenase activity
FOC89_RS09895	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOC89_RS09900	COG2267	carboxylic ester hydrolase activity
FOC89_RS09910	COG0745	RESPONSE REGULATOR receiver
FOC89_RS09920	COG0666	response to abiotic stimulus
FOC89_RS09955	COG1609	Transcriptional regulator
FOC89_RS09960	COG4851	CamS sex pheromone cAM373 precursor
FOC89_RS09965	COG3118	belongs to the thioredoxin family
FOC89_RS09975	COG2309	aminopeptidase activity
FOC89_RS10000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC89_RS10005	COG0697	spore germination
FOC89_RS10010	COG0789	Transcriptional regulator
FOC89_RS10025	COG1674	ftsk spoiiie
FOC89_RS10035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC89_RS10045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC89_RS10050	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC89_RS10055	COG1363	Peptidase, m42
FOC89_RS10065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC89_RS10080	COG0510	thiamine kinase activity
FOC89_RS10085	COG1523	belongs to the glycosyl hydrolase 13 family
FOC89_RS10095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC89_RS10100	COG1349	DNA-binding transcription factor activity
FOC89_RS10105	COG1187	pseudouridine synthase activity
FOC89_RS10110	COG2244	polysaccharide biosynthetic process
FOC89_RS10115	COG2081	HI0933 family
FOC89_RS10120	COG2814	Major facilitator Superfamily
FOC89_RS10130	COG3832	glyoxalase III activity
FOC89_RS10150	COG1329	Transcriptional regulator
FOC89_RS10175	COG0314	molybdopterin synthase activity
FOC89_RS10180	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC89_RS10185	COG0303	'Molybdopterin
FOC89_RS10195	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC89_RS10200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC89_RS10220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC89_RS10230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC89_RS10270	COG2814	Major facilitator Superfamily
FOC89_RS10275	COG0475	glutathione-regulated potassium exporter activity
FOC89_RS10280	COG0490	domain, Protein
FOC89_RS10285	COG0582	viral genome integration into host DNA
FOC89_RS10295	COG1136	(ABC) transporter
FOC89_RS10315	COG1242	4 iron, 4 sulfur cluster binding
FOC89_RS10320	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC89_RS10325	COG1131	(ABC) transporter
FOC89_RS10335	COG1794	racemase activity, acting on amino acids and derivatives
FOC89_RS10355	COG2267	carboxylic ester hydrolase activity
FOC89_RS10360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC89_RS10365	COG0671	phosphoesterase, PA-phosphatase related
FOC89_RS10370	COG0438	transferase activity, transferring glycosyl groups
FOC89_RS10380	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC89_RS10435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC89_RS10440	COG5002	protein histidine kinase activity
FOC89_RS10445	COG4191	Histidine kinase
FOC89_RS10450	COG2267	carboxylic ester hydrolase activity
FOC89_RS10455	COG1368	sulfuric ester hydrolase activity
FOC89_RS10470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC89_RS10475	COG1116	anion transmembrane transporter activity
FOC89_RS10480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC89_RS10495	COG0546	phosphoglycolate phosphatase activity
FOC89_RS10505	COG0494	nUDIX hydrolase
FOC89_RS10540	COG0288	reversible hydration of carbon dioxide
FOC89_RS10545	COG1271	oxidase subunit
FOC89_RS10550	COG1294	oxidase, subunit
FOC89_RS10570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC89_RS10595	COG1842	Phage shock protein A
FOC89_RS10625	COG5002	protein histidine kinase activity
FOC89_RS10630	COG0745	RESPONSE REGULATOR receiver
FOC89_RS10660	COG1597	lipid kinase activity
FOC89_RS10685	COG0586	Pfam SNARE associated Golgi protein
FOC89_RS10695	COG0577	efflux transmembrane transporter activity
FOC89_RS10700	COG1136	(ABC) transporter
FOC89_RS10705	COG2207	Transcriptional regulator
FOC89_RS10705	COG3708	Transcriptional regulator
FOC89_RS10710	COG0745	RESPONSE REGULATOR receiver
FOC89_RS10715	COG2205	protein histidine kinase activity
FOC89_RS10720	COG0577	efflux transmembrane transporter activity
FOC89_RS10725	COG0577	efflux transmembrane transporter activity
FOC89_RS10730	COG1136	(ABC) transporter
FOC89_RS10735	COG0577	efflux transmembrane transporter activity
FOC89_RS10750	COG2188	Transcriptional regulator
FOC89_RS10770	COG3964	amidohydrolase
FOC89_RS10800	COG4948	Mandelate Racemase Muconate Lactonizing
FOC89_RS10810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC89_RS10815	COG0596	Alpha beta hydrolase
FOC89_RS10820	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC89_RS10825	COG1169	isochorismate synthase
FOC89_RS10830	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC89_RS10835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC89_RS10855	COG0058	SHG alpha-glucan phosphorylase activity
FOC89_RS10865	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC89_RS10900	COG1595	DNA-templated transcription, initiation
FOC89_RS10995	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC89_RS11030	COG1285	pathogenesis
FOC89_RS11035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC89_RS11050	COG2155	Conserved Protein
FOC89_RS11055	COG1098	S1 RNA binding domain
FOC89_RS11060	COG0436	Aminotransferase
FOC89_RS11065	COG1522	sequence-specific DNA binding
FOC89_RS11070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC89_RS11075	COG2267	carboxylic ester hydrolase activity
FOC89_RS11085	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC89_RS11105	COG5018	Exonuclease
FOC89_RS11110	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC89_RS11130	COG2050	protein possibly involved in aromatic compounds catabolism
FOC89_RS11140	COG1268	BioY protein
FOC89_RS11150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC89_RS11155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC89_RS11170	COG3584	3D domain protein
FOC89_RS11185	COG1252	NADH dehydrogenase
FOC89_RS11200	COG3708	Transcriptional regulator
FOC89_RS11215	COG1683	Conserved Protein
FOC89_RS11230	COG0316	Belongs to the HesB IscA family
FOC89_RS11245	COG1252	NADH dehydrogenase
FOC89_RS11255	COG2274	protein secretion by the type I secretion system
FOC89_RS11260	COG0390	transport system, permease component
FOC89_RS11265	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC89_RS11285	COG4837	Protein of unknown function (DUF1462)
FOC89_RS11290	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC89_RS11300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC89_RS11305	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC89_RS11315	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC89_RS11325	COG0647	UMP catabolic process
FOC89_RS11335	COG2445	Protein of unknown function DUF86
FOC89_RS11340	COG1494	fructose-1,6-bisphosphatase
FOC89_RS11355	COG4470	Protein conserved in bacteria
FOC89_RS11365	COG0789	Transcriptional regulator
FOC89_RS11370	COG4377	Putative membrane peptidase family (DUF2324)
FOC89_RS11395	COG0739	heme binding
FOC89_RS11405	COG3377	Domain of unknown function (DUF1805)
FOC89_RS11410	COG0737	Belongs to the 5'-nucleotidase family
FOC89_RS11415	COG0719	Fe-S assembly protein
FOC89_RS11420	COG0822	iron-sulfur transferase activity
FOC89_RS11425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC89_RS11430	COG0719	Fe-S assembly protein
FOC89_RS11435	COG0396	ATPase activity
FOC89_RS11440	COG1464	Belongs to the NlpA lipoprotein family
FOC89_RS11445	COG1464	Belongs to the NlpA lipoprotein family
FOC89_RS11450	COG2011	ABC-type metal ion transport system permease component
FOC89_RS11465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC89_RS11470	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC89_RS11480	COG1393	Belongs to the ArsC family
FOC89_RS11560	COG1396	sequence-specific DNA binding
FOC89_RS11565	COG1309	transcriptional regulator
FOC89_RS11570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC89_RS11575	COG1960	acyl-CoA dehydrogenase activity
FOC89_RS11580	COG0183	Belongs to the thiolase family
FOC89_RS11585	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC89_RS11585	COG1024	Enoyl-CoA hydratase
FOC89_RS11595	COG1686	Belongs to the peptidase S11 family
FOC89_RS11610	COG0011	TIGRFAM Protein of
FOC89_RS11615	COG0840	transmembrane signaling receptor activity
FOC89_RS11635	COG2814	Major facilitator Superfamily
FOC89_RS11640	COG0531	amino acid
FOC89_RS11650	COG0706	membrane insertase activity
FOC89_RS11660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC89_RS11695	COG0586	Pfam SNARE associated Golgi protein
FOC89_RS11705	COG1376	ErfK ybiS ycfS ynhG family protein
FOC89_RS11710	COG0745	RESPONSE REGULATOR receiver
FOC89_RS11715	COG5002	protein histidine kinase activity
FOC89_RS11740	COG0840	transmembrane signaling receptor activity
FOC89_RS11745	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC89_RS11750	COG3227	Zinc metalloprotease (Elastase)
FOC89_RS11755	COG1741	Belongs to the pirin family
FOC89_RS11770	COG0475	glutathione-regulated potassium exporter activity
FOC89_RS11775	COG0490	domain, Protein
FOC89_RS11780	COG1115	amino acid carrier protein
FOC89_RS11785	COG0783	Belongs to the Dps family
FOC89_RS11800	COG1611	Belongs to the LOG family
FOC89_RS11820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC89_RS11825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC89_RS11830	COG1115	amino acid carrier protein
FOC89_RS11835	COG2910	NAD(P)H-binding
FOC89_RS11855	COG0656	L-ascorbic acid biosynthetic process
FOC89_RS11860	COG2814	Major facilitator Superfamily
FOC89_RS11865	COG1733	regulation of RNA biosynthetic process
FOC89_RS11875	COG1252	NADH dehydrogenase
FOC89_RS11880	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC89_RS11885	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC89_RS11910	COG3290	protein histidine kinase activity
FOC89_RS11910	COG0840	transmembrane signaling receptor activity
FOC89_RS11940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC89_RS12040	COG0557	exoribonuclease II activity
FOC89_RS12045	COG1647	Serine aminopeptidase, S33
FOC89_RS12050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC89_RS12055	COG1346	cytolysis
FOC89_RS12090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC89_RS12105	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC89_RS12130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC89_RS12145	COG2323	membrane
FOC89_RS12155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC89_RS12165	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC89_RS12175	COG1051	belongs to the nudix hydrolase family
FOC89_RS12185	COG0492	ferredoxin-NADP+ reductase activity
FOC89_RS12190	COG0457	Tetratricopeptide repeat
FOC89_RS12195	COG0110	maltose O-acetyltransferase activity
FOC89_RS12215	COG1950	PFAM Membrane protein of
FOC89_RS12225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC89_RS12230	COG0556	nucleotide-excision repair
FOC89_RS12245	COG0789	Transcriptional regulator
FOC89_RS12270	COG2855	membrane
FOC89_RS12275	COG0583	DNA-binding transcription factor activity
FOC89_RS12285	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC89_RS12300	COG1132	(ABC) transporter
FOC89_RS12305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC89_RS12310	COG0793	Belongs to the peptidase S41A family
FOC89_RS12310	COG3409	Peptidoglycan-binding domain 1 protein
FOC89_RS12315	COG2177	Part of the ABC transporter FtsEX involved in
FOC89_RS12320	COG2884	Cell division ATP-binding protein ftsE
FOC89_RS12340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC89_RS12345	COG1278	Cold shock
FOC89_RS12350	COG1040	competence protein
FOC89_RS12355	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOC89_RS12360	COG1388	LysM domain
FOC89_RS12360	COG0791	NLP P60 protein
FOC89_RS12365	COG1733	regulation of RNA biosynthetic process
FOC89_RS12370	COG1307	EDD domain protein, DegV family
FOC89_RS12375	COG1739	Uncharacterized protein family UPF0029
FOC89_RS12380	COG1316	TRANSCRIPTIONal
FOC89_RS12385	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC89_RS12390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC89_RS12395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC89_RS12405	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FOC89_RS12405	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC89_RS12425	COG1486	melibiose metabolic process
FOC89_RS12430	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC89_RS12435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC89_RS12445	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC89_RS12455	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC89_RS12465	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC89_RS12470	COG1301	dicarboxylic acid transport
FOC89_RS12480	COG0346	lactoylglutathione lyase activity
FOC89_RS12485	COG1511	domain protein
FOC89_RS12490	COG0583	DNA-binding transcription factor activity
FOC89_RS12495	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC89_RS12505	COG1271	oxidase subunit
FOC89_RS12510	COG1294	oxidase, subunit
FOC89_RS12515	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC89_RS12525	COG1620	l-lactate permease
FOC89_RS12535	COG2389	metal-binding protein
FOC89_RS12545	COG1368	sulfuric ester hydrolase activity
FOC89_RS12555	COG0791	NLP P60 protein
FOC89_RS12555	COG1388	LysM domain
FOC89_RS12560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC89_RS12570	COG1215	transferase activity, transferring glycosyl groups
FOC89_RS12575	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC89_RS12580	COG3584	3D domain protein
FOC89_RS12580	COG1388	LysM domain
FOC89_RS12605	COG4715	Zinc finger, swim domain protein
FOC89_RS12610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC89_RS12655	COG0577	efflux transmembrane transporter activity
FOC89_RS12660	COG1136	(ABC) transporter
FOC89_RS12695	COG5002	protein histidine kinase activity
FOC89_RS12700	COG0745	RESPONSE REGULATOR receiver
FOC89_RS12705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC89_RS12715	COG1316	TRANSCRIPTIONal
FOC89_RS12720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC89_RS12725	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC89_RS12730	COG1215	transferase activity, transferring glycosyl groups
FOC89_RS12755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC89_RS12760	COG4464	protein tyrosine phosphatase activity
FOC89_RS12765	COG0489	protein tyrosine kinase activity
FOC89_RS12770	COG3944	biosynthesis protein
FOC89_RS12775	COG0489	protein tyrosine kinase activity
FOC89_RS12790	COG1609	Transcriptional regulator
FOC89_RS12800	COG0739	heme binding
FOC89_RS12815	COG3279	Response regulator of the LytR AlgR family
FOC89_RS12820	COG2385	sporulation resulting in formation of a cellular spore
FOC89_RS12835	COG4836	Membrane
FOC89_RS12840	COG1007	ATP synthesis coupled electron transport
FOC89_RS12845	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC89_RS12850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC89_RS12860	COG0839	Belongs to the complex I subunit 6 family
FOC89_RS12875	COG0649	NAD binding
FOC89_RS12880	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC89_RS12895	COG3300	MHYT domain
FOC89_RS12895	COG5001	Diguanylate cyclase
FOC89_RS12945	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC89_RS12980	COG0698	ribose 5-phosphate isomerase
FOC89_RS12990	COG2190	(PTS) system
FOC89_RS12995	COG2259	Doxx family
FOC89_RS13000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC89_RS13015	COG0009	L-threonylcarbamoyladenylate synthase
FOC89_RS13030	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC89_RS13050	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC89_RS13055	COG1494	fructose-1,6-bisphosphatase
FOC89_RS13075	COG4821	SIS domain
FOC89_RS13095	COG1960	acyl-CoA dehydrogenase activity
FOC89_RS13100	COG1960	acyl-CoA dehydrogenase activity
FOC89_RS13105	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC89_RS13110	COG0183	Belongs to the thiolase family
FOC89_RS13115	COG2181	nitrate reductase activity
FOC89_RS13115	COG0247	lactate metabolic process
FOC89_RS13120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC89_RS13130	COG5001	Diguanylate cyclase
FOC89_RS13130	COG3300	MHYT domain
FOC89_RS13160	COG0024	Methionine aminopeptidase
FOC89_RS13170	COG2234	aminopeptidase activity
FOC89_RS13190	COG1595	DNA-templated transcription, initiation
FOC89_RS13200	COG4506	Protein conserved in bacteria
FOC89_RS13205	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC89_RS13220	COG0010	Belongs to the arginase family
FOC89_RS13230	COG2814	Major facilitator Superfamily
FOC89_RS13235	COG0789	Transcriptional regulator
FOC89_RS13240	COG0584	glycerophosphoryl diester phosphodiesterase
FOC89_RS13245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC89_RS13255	COG1994	Peptidase M50
FOC89_RS13265	COG1078	dGTPase activity
FOC89_RS13270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC89_RS13275	COG1120	ATPase activity
FOC89_RS13280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC89_RS13285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC89_RS13305	COG0095	Lipoate-protein ligase
FOC89_RS13310	COG0280	phosphate acetyltransferase
FOC89_RS13325	COG3773	Cell wall hydrolase
FOC89_RS13335	COG2363	Small membrane protein
FOC89_RS13345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC89_RS13350	COG2233	PERMEase
FOC89_RS13355	COG0561	phosphatase activity
FOC89_RS13360	COG2814	Major facilitator Superfamily
FOC89_RS13370	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC89_RS13375	COG1131	(ABC) transporter
FOC89_RS13380	COG2755	lipolytic protein G-D-S-L family
FOC89_RS13385	COG1609	Transcriptional regulator
FOC89_RS13395	COG0460	homoserine dehydrogenase
FOC89_RS13405	COG2873	o-acetylhomoserine
FOC89_RS13415	COG1011	Hydrolase
FOC89_RS13420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC89_RS13430	COG2197	response regulator
FOC89_RS13435	COG2203	Gaf domain
FOC89_RS13435	COG4585	Histidine kinase
FOC89_RS13440	COG0351	phosphomethylpyrimidine kinase
FOC89_RS13445	COG3706	GGDEF domain
FOC89_RS13450	COG2879	small protein
FOC89_RS13455	COG1966	Carbon starvation protein
FOC89_RS13460	COG3279	Response regulator of the LytR AlgR family
FOC89_RS13465	COG0477	Major facilitator Superfamily
FOC89_RS13490	COG0840	transmembrane signaling receptor activity
FOC89_RS13500	COG1607	acyl-coa hydrolase
FOC89_RS13515	COG0488	(ABC) transporter
FOC89_RS13535	COG0463	Glycosyl transferase, family 2
FOC89_RS13540	COG1309	transcriptional regulator
FOC89_RS13545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC89_RS13550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC89_RS13550	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC89_RS13555	COG0628	permease
FOC89_RS13570	COG3279	Response regulator of the LytR AlgR family
FOC89_RS13575	COG3275	phosphorelay sensor kinase activity
FOC89_RS13580	COG2814	Major facilitator Superfamily
FOC89_RS13585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC89_RS13590	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOC89_RS13595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC89_RS13615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC89_RS13620	COG1272	protein, Hemolysin III
FOC89_RS13645	COG1164	Oligoendopeptidase f
FOC89_RS13665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC89_RS13670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC89_RS13675	COG4853	Protein conserved in bacteria
FOC89_RS13680	COG4863	YycH protein
FOC89_RS13685	COG5002	protein histidine kinase activity
FOC89_RS13690	COG0745	RESPONSE REGULATOR receiver
FOC89_RS13720	COG0305	Participates in initiation and elongation during chromosome replication
FOC89_RS13730	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOC89_RS13735	COG4241	membrane
FOC89_RS13745	COG0629	single-stranded DNA binding
FOC89_RS13755	COG0012	GTP binding
FOC89_RS13760	COG4481	Protein conserved in bacteria
FOC89_RS13765	COG0668	transmembrane transport
FOC89_RS13775	COG1475	DNA binding
FOC89_RS13780	COG1192	Involved in chromosome partitioning
FOC89_RS13805	COG1847	R3H domain protein
FOC89_RS13810	COG0706	membrane insertase activity
FOC89_RS13820	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOC89_RS13830	COG0592	DNA-directed DNA polymerase activity
FOC89_RS13835	COG2501	S4 domain
FOC89_RS13845	COG0187	DNA topoisomerase II activity
FOC89_RS13850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC89_RS13885	COG0516	GMP reductase activity
FOC89_RS13885	COG0517	IMP dehydrogenase activity
FOC89_RS13890	COG1686	Belongs to the peptidase S11 family
FOC89_RS13920	COG1428	Deoxynucleoside kinase
FOC89_RS13925	COG1428	Deoxynucleoside kinase
FOC89_RS13930	COG1335	isochorismatase
FOC89_RS13935	COG0590	tRNA wobble adenosine to inosine editing
FOC89_RS13945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC89_RS14000	COG1982	Orn Lys Arg decarboxylase major
FOC89_RS14010	COG0470	DNA polymerase III
FOC89_RS14015	COG1774	PSP1 C-terminal conserved region
FOC89_RS14025	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC89_RS14035	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC89_RS14040	COG2002	toxin-antitoxin pair type II binding
FOC89_RS14045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC89_RS14045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC89_RS14050	COG0084	hydrolase, TatD family'
FOC89_RS14055	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC89_RS14070	COG4466	Protein conserved in bacteria
FOC89_RS14085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC89_RS14090	COG0251	oxidation-reduction process
FOC89_RS14120	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC89_RS14125	COG2002	toxin-antitoxin pair type II binding
FOC89_RS14130	COG2244	polysaccharide biosynthetic process
FOC89_RS14135	COG3956	TIGRFAM MazG family protein
FOC89_RS14140	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC89_RS14160	COG1098	S1 RNA binding domain
FOC89_RS14175	COG2208	phosphoserine phosphatase activity
FOC89_RS14190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC89_RS14205	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC89_RS14210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC89_RS14215	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC89_RS14220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC89_RS14225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC89_RS14230	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC89_RS14235	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC89_RS14240	COG1396	sequence-specific DNA binding
FOC89_RS14245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC89_RS14335	COG3880	PFAM UvrB UvrC protein
FOC89_RS14345	COG0542	response to heat
FOC89_RS14350	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC89_RS14360	COG4956	integral membrane protein (PIN domain superfamily)
FOC89_RS14380	COG1045	serine acetyltransferase
FOC89_RS14395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC89_RS14400	COG3688	RNA-binding protein containing a PIN domain
FOC89_RS14415	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC89_RS14420	COG0250	Participates in transcription elongation, termination and antitermination
FOC89_RS14425	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOC89_RS14445	COG2813	Specifically methylates the guanine in position
FOC89_RS14460	COG1358	cellular component organization or biogenesis
FOC89_RS14530	COG0255	Belongs to the universal ribosomal protein uL29 family
FOC89_RS14590	COG0201	protein transport
FOC89_RS14600	COG0024	Methionine aminopeptidase
FOC89_RS14610	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC89_RS14645	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC89_RS14670	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC89_RS14675	COG0489	protein tyrosine kinase activity
FOC89_RS14685	COG2194	sulfuric ester hydrolase activity
FOC89_RS14690	COG0726	polysaccharide deacetylase
FOC89_RS14770	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC89_RS14775	COG4856	YbbR-like protein
FOC89_RS14790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOC89_RS14795	COG0596	Alpha beta hydrolase
FOC89_RS14815	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC89_RS14820	COG4946	Tricorn protease homolog
FOC89_RS14820	COG1506	peptidase
FOC89_RS14820	COG0823	Involved in the tonB-independent uptake of proteins
FOC89_RS14860	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS14865	COG2011	ABC-type metal ion transport system permease component
FOC89_RS14870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC89_RS14875	COG1464	Belongs to the NlpA lipoprotein family
FOC89_RS14880	COG0604	alcohol dehydrogenase
FOC89_RS14890	COG0277	FAD linked oxidase domain protein
FOC89_RS14895	COG2271	Major facilitator Superfamily
FOC89_RS14905	COG2814	Major facilitator Superfamily
FOC89_RS14920	COG0601	transmembrane transport
FOC89_RS14925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC89_RS14930	COG0444	Belongs to the ABC transporter superfamily
FOC89_RS14935	COG4608	Belongs to the ABC transporter superfamily
FOC89_RS14940	COG4166	transmembrane transport
FOC89_RS14950	COG2207	Transcriptional regulator
FOC89_RS14960	COG1309	transcriptional regulator
FOC89_RS14970	COG4166	transmembrane transport
FOC89_RS14975	COG4166	transmembrane transport
FOC89_RS14980	COG0656	L-ascorbic acid biosynthetic process
FOC89_RS14985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC89_RS15000	COG4149	molybdate abc transporter
FOC89_RS15005	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC89_RS15010	COG1910	domain protein
FOC89_RS15025	COG0697	spore germination
FOC89_RS15040	COG0204	Acyl-transferase
FOC89_RS15050	COG1609	Transcriptional regulator
FOC89_RS15060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC89_RS15070	COG0084	hydrolase, TatD family'
FOC89_RS15075	COG5298	Protein conserved in bacteria
FOC89_RS15100	COG0488	(ABC) transporter
FOC89_RS15105	COG4585	Histidine kinase
FOC89_RS15110	COG2197	response regulator
FOC89_RS15115	COG1131	(ABC) transporter
FOC89_RS15120	COG1511	domain protein
FOC89_RS15120	COG0842	Transport permease protein
FOC89_RS15125	COG0842	Transport permease protein
FOC89_RS15135	COG0747	negative chemotaxis
FOC89_RS15140	COG0601	transmembrane transport
FOC89_RS15145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC89_RS15150	COG0444	Belongs to the ABC transporter superfamily
FOC89_RS15155	COG4608	Belongs to the ABC transporter superfamily
FOC89_RS15160	COG0561	phosphatase activity
FOC89_RS15185	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FOC89_RS15190	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC89_RS15210	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC89_RS15220	COG4294	response to UV
FOC89_RS15225	COG0457	Tetratricopeptide repeat
FOC89_RS15225	COG0705	Rhomboid family
FOC89_RS15235	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC89_RS15240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC89_RS15245	COG0864	Transcriptional regulator
FOC89_RS15250	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOC89_RS15255	COG2183	response to ionizing radiation
FOC89_RS15350	COG0802	atpase or kinase
FOC89_RS15355	COG1214	PFAM Peptidase M22, glycoprotease
FOC89_RS15360	COG0456	acetyltransferase
FOC89_RS15370	COG0488	(ABC) transporter
FOC89_RS15385	COG1266	CAAX protease self-immunity
FOC89_RS15405	COG2252	PERMEase
FOC89_RS15415	COG5002	protein histidine kinase activity
FOC89_RS15440	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC89_RS15470	COG2226	methyltransferase
FOC89_RS15490	COG1215	transferase activity, transferring glycosyl groups
FOC89_RS15530	COG2205	protein histidine kinase activity
FOC89_RS15535	COG0745	RESPONSE REGULATOR receiver
FOC89_RS15555	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC89_RS15560	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC89_RS15565	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC89_RS15575	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC89_RS15590	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC89_RS15600	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC89_RS15610	COG0151	Belongs to the GarS family
FOC89_RS15635	COG0210	DNA helicase
FOC89_RS15645	COG4851	CamS sex pheromone cAM373 precursor
FOC89_RS15665	COG1335	isochorismatase
FOC89_RS15670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC89_RS15675	COG2011	ABC-type metal ion transport system permease component
FOC89_RS15680	COG1464	Belongs to the NlpA lipoprotein family
FOC89_RS15695	COG0003	Pfam Anion-transporting ATPase
FOC89_RS15700	COG1846	Transcriptional regulator
FOC89_RS15705	COG4682	membrane
FOC89_RS15725	COG1597	lipid kinase activity
FOC89_RS15730	COG0546	phosphoglycolate phosphatase activity
FOC89_RS15735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC89_RS15745	COG1012	belongs to the aldehyde dehydrogenase family
FOC89_RS15750	COG2076	Multidrug Resistance protein
FOC89_RS15755	COG2309	aminopeptidase activity
FOC89_RS15770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC89_RS15775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC89_RS15780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC89_RS15790	COG4807	Protein conserved in bacteria
FOC89_RS15820	COG1473	amidohydrolase
FOC89_RS15835	COG0450	alkyl hydroperoxide reductase
FOC89_RS15855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC89_RS15860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC89_RS15865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC89_RS15880	COG0166	Belongs to the GPI family
FOC89_RS15905	COG5002	protein histidine kinase activity
FOC89_RS15925	COG3541	Predicted nucleotidyltransferase
FOC89_RS15935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC89_RS15935	COG0723	plastoquinol--plastocyanin reductase activity
FOC89_RS15945	COG0765	amino acid transport
FOC89_RS15950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC89_RS15960	COG0840	transmembrane signaling receptor activity
FOC89_RS16000	COG0366	Alpha amylase catalytic
FOC89_RS16005	COG1263	PTS System
FOC89_RS16005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC89_RS16005	COG2190	(PTS) system
FOC89_RS16035	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC89_RS16050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC89_RS16060	COG1116	anion transmembrane transporter activity
FOC89_RS16065	COG0488	(ABC) transporter
FOC89_RS16115	COG2270	Major facilitator Superfamily
FOC89_RS16145	COG2310	stress, protein
FOC89_RS16150	COG2310	stress, protein
FOC89_RS16155	COG2310	stress, protein
FOC89_RS16160	COG0861	Integral membrane protein TerC family
FOC89_RS16170	COG3853	Toxic anion resistance protein (TelA)
FOC89_RS16185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC89_RS16195	COG1295	ribonuclease BN
FOC89_RS16200	COG2217	Heavy metal translocating P-type atpase
FOC89_RS16205	COG0697	spore germination
FOC89_RS16220	COG0681	Belongs to the peptidase S26 family
FOC89_RS16230	COG0586	Pfam SNARE associated Golgi protein
FOC89_RS16245	COG3871	stress protein (general stress protein 26)
FOC89_RS16250	COG0387	Pfam Sodium calcium exchanger
FOC89_RS16260	COG0535	radical SAM domain protein
FOC89_RS16280	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC89_RS16285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC89_RS16300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC89_RS16330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC89_RS16330	COG1263	PTS System
FOC89_RS16335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC89_RS16350	COG0463	Glycosyl transferase, family 2
FOC89_RS16360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC89_RS16360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC89_RS16380	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC89_RS16400	COG1228	amidohydrolase
FOC89_RS16405	COG1090	epimerase
FOC89_RS16435	COG1988	membrane-bound metal-dependent
FOC89_RS16440	COG1194	a g-specific adenine glycosylase
FOC89_RS16465	COG1132	(ABC) transporter
FOC89_RS16470	COG4129	membrane
FOC89_RS16475	COG0067	glutamate synthase
FOC89_RS16475	COG0069	glutamate synthase activity
FOC89_RS16475	COG0070	glutamate synthase
FOC89_RS16485	COG4555	ABC transporter
FOC89_RS16505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC89_RS16510	COG0735	belongs to the Fur family
FOC89_RS16625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC89_RS16630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC89_RS16640	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC89_RS16650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC89_RS16660	COG2766	serine protein kinase
FOC89_RS16680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC89_RS16690	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC89_RS16695	COG2268	Band 7 protein
FOC89_RS16705	COG3290	protein histidine kinase activity
FOC89_RS16710	COG4565	transcriptional regulatory protein
FOC89_RS16715	COG2851	Citrate transporter
FOC89_RS16735	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC89_RS16740	COG3842	ATPase activity
FOC89_RS16745	COG1175	transmembrane transport
FOC89_RS16750	COG0395	ABC-type sugar transport system, permease component
FOC89_RS16760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC89_RS16765	COG0745	RESPONSE REGULATOR receiver
FOC89_RS16770	COG5002	protein histidine kinase activity
FOC89_RS16780	COG4990	cell redox homeostasis
FOC89_RS16790	COG3290	protein histidine kinase activity
FOC89_RS16795	COG4565	transcriptional regulatory protein
FOC89_RS16800	COG3493	citrate carrier protein
FOC89_RS16805	COG0281	malic enzyme
FOC89_RS16820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC89_RS16830	COG5002	protein histidine kinase activity
FOC89_RS16835	COG0745	RESPONSE REGULATOR receiver
FOC89_RS16840	COG0454	-acetyltransferase
FOC89_RS16840	COG0456	acetyltransferase
FOC89_RS16845	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC89_RS16850	COG3383	formate dehydrogenase (NAD+) activity
FOC89_RS16855	COG2427	Protein of unknown function (DUF1641)
FOC89_RS16870	COG0531	amino acid
FOC89_RS16875	COG0640	Transcriptional regulator
FOC89_RS16880	COG2217	Heavy metal translocating P-type atpase
FOC89_RS16885	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC89_RS16900	COG3227	Zinc metalloprotease (Elastase)
FOC89_RS16920	COG2720	vancomycin resistance protein
FOC89_RS16925	COG1316	TRANSCRIPTIONal
FOC89_RS16930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC89_RS16935	COG0346	lactoylglutathione lyase activity
FOC89_RS16940	COG1253	flavin adenine dinucleotide binding
FOC89_RS16945	COG1027	Aspartate ammonia-lyase
FOC89_RS16950	COG1620	l-lactate permease
FOC89_RS16965	COG3104	oligopeptide transport
FOC89_RS16970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC89_RS16975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC89_RS16980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC89_RS16995	COG0156	8-amino-7-oxononanoate synthase activity
FOC89_RS17000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC89_RS17005	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOC89_RS17015	COG4548	von Willebrand factor, type A
FOC89_RS17020	COG0714	Associated with various cellular activities
FOC89_RS17025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC89_RS17045	COG0531	amino acid
FOC89_RS17050	COG2188	Transcriptional regulator
FOC89_RS17055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC89_RS17055	COG1263	PTS System
FOC89_RS17060	COG0366	Alpha amylase catalytic
FOC89_RS17075	COG0697	spore germination
FOC89_RS17085	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC89_RS17090	COG1115	amino acid carrier protein
FOC89_RS17095	COG1126	abc transporter atp-binding protein
FOC89_RS17100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC89_RS17105	COG0765	amino acid transport
FOC89_RS17110	COG0765	amino acid transport
FOC89_RS17115	COG0833	amino acid
FOC89_RS17140	COG2378	regulation of single-species biofilm formation
FOC89_RS17145	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC89_RS17150	COG5002	protein histidine kinase activity
FOC89_RS17165	COG0659	secondary active sulfate transmembrane transporter activity
FOC89_RS17180	COG0747	negative chemotaxis
FOC89_RS17190	COG0601	transmembrane transport
FOC89_RS17195	COG4608	Belongs to the ABC transporter superfamily
FOC89_RS17205	COG2271	Major facilitator Superfamily
FOC89_RS17210	COG1846	Transcriptional regulator
FOC89_RS17215	COG0477	Major facilitator Superfamily
FOC89_RS17220	COG1609	Transcriptional regulator
FOC89_RS17225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC89_RS17240	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC89_RS17245	COG1879	ABC-type sugar transport system periplasmic component
FOC89_RS17265	COG1063	alcohol dehydrogenase
FOC89_RS17280	COG3568	Endonuclease Exonuclease Phosphatase
FOC89_RS17310	COG0840	transmembrane signaling receptor activity
FOC89_RS17315	COG3584	3D domain protein
FOC89_RS17315	COG1388	LysM domain
FOC89_RS17320	COG1476	TRANSCRIPTIONal
FOC89_RS17335	COG3104	oligopeptide transport
FOC89_RS17340	COG1114	Component of the transport system for branched-chain amino acids
FOC89_RS17355	COG1113	amino acid transport
FOC89_RS17360	COG2252	PERMEase
FOC89_RS17375	COG2153	protein acetylation
FOC89_RS17385	COG0475	glutathione-regulated potassium exporter activity
FOC89_RS17385	COG0569	domain protein
FOC89_RS17400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC89_RS17405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC89_RS17410	COG0833	amino acid
FOC89_RS17415	COG4990	cell redox homeostasis
FOC89_RS17430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC89_RS17435	COG0697	spore germination
FOC89_RS17440	COG0531	amino acid
FOC89_RS17450	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC89_RS17455	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC89_RS17460	COG1918	ferrous iron import across plasma membrane
FOC89_RS17460	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC89_RS17465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC89_RS17470	COG0573	inorganic phosphate transmembrane transporter activity
FOC89_RS17475	COG0581	inorganic phosphate transmembrane transporter activity
FOC89_RS17485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC89_RS17605	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOC89_RS17625	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC89_RS17630	COG1116	anion transmembrane transporter activity
FOC89_RS17635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC89_RS17640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC89_RS17645	COG0352	thiamine-phosphate diphosphorylase activity
FOC89_RS17650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC89_RS17655	COG2104	thiamine diphosphate biosynthetic process
FOC89_RS17665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC89_RS17670	COG0351	phosphomethylpyrimidine kinase
FOC89_RS17710	COG2205	protein histidine kinase activity
FOC89_RS17715	COG2814	Major facilitator Superfamily
FOC89_RS17720	COG1846	Transcriptional regulator
FOC89_RS17735	COG2252	PERMEase
FOC89_RS17740	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS17745	COG1376	ErfK ybiS ycfS ynhG family protein
FOC89_RS17760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC89_RS17800	COG0778	Nitroreductase
FOC89_RS17805	COG2719	SpoVR family
FOC89_RS17815	COG3591	Belongs to the peptidase S1B family
FOC89_RS17825	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC89_RS17830	COG1937	Protein conserved in bacteria
FOC89_RS17835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC89_RS17835	COG0425	Belongs to the sulfur carrier protein TusA family
FOC89_RS17840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC89_RS17840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC89_RS17845	COG0425	Belongs to the sulfur carrier protein TusA family
FOC89_RS17850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC89_RS17860	COG2210	Belongs to the sulfur carrier protein TusA family
FOC89_RS17865	COG0730	response to heat
FOC89_RS17875	COG1316	TRANSCRIPTIONal
FOC89_RS17880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC89_RS17885	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC89_RS17900	COG3711	transcriptional antiterminator
FOC89_RS17900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC89_RS17905	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC89_RS17910	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC89_RS17930	COG3584	3D domain protein
FOC89_RS17930	COG1388	LysM domain
FOC89_RS17935	COG0577	efflux transmembrane transporter activity
FOC89_RS17940	COG1136	(ABC) transporter
FOC89_RS17950	COG5522	Integral membrane protein (intg_mem_TP0381)
FOC89_RS17965	COG1114	Component of the transport system for branched-chain amino acids
FOC89_RS17970	COG3546	catalase activity
FOC89_RS18005	COG0586	Pfam SNARE associated Golgi protein
FOC89_RS18040	COG0531	amino acid
FOC89_RS18045	COG0475	glutathione-regulated potassium exporter activity
FOC89_RS18055	COG1737	Transcriptional regulator
FOC89_RS18065	COG1263	PTS System
FOC89_RS18065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC89_RS18075	COG2259	Doxx family
FOC89_RS18095	COG1522	sequence-specific DNA binding
FOC89_RS18110	COG2076	Multidrug Resistance protein
FOC89_RS18115	COG1309	transcriptional regulator
FOC89_RS18120	COG2814	Major facilitator Superfamily
FOC89_RS18125	COG1733	regulation of RNA biosynthetic process
FOC89_RS18135	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC89_RS18145	COG4533	DNA binding
FOC89_RS18150	COG2211	Major facilitator Superfamily
FOC89_RS18160	COG0693	protein deglycase activity
FOC89_RS18165	COG0753	catalase activity
FOC89_RS18165	COG0693	protein deglycase activity
FOC89_RS18175	COG0531	amino acid
FOC89_RS18180	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC89_RS18190	COG1012	belongs to the aldehyde dehydrogenase family
FOC89_RS18195	COG1132	(ABC) transporter
FOC89_RS18200	COG1132	(ABC) transporter
FOC89_RS18205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC89_RS18210	COG0765	amino acid transport
FOC89_RS18215	COG1126	abc transporter atp-binding protein
FOC89_RS18230	COG0189	ligase activity
FOC89_RS18260	COG0028	Belongs to the TPP enzyme family
FOC89_RS18265	COG3527	Alpha-acetolactate decarboxylase
FOC89_RS18275	COG0561	phosphatase activity
FOC89_RS18285	COG3409	Peptidoglycan-binding domain 1 protein
FOC89_RS18285	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC89_RS18290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC89_RS18305	COG0659	secondary active sulfate transmembrane transporter activity
FOC89_RS18330	COG0653	protein targeting
FOC89_RS18335	COG2244	polysaccharide biosynthetic process
FOC89_RS18345	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC89_RS18350	COG4196	transglutaminase domain protein
FOC89_RS18365	COG1696	Membrane protein involved in D-alanine export
FOC89_RS18380	COG1024	Enoyl-CoA hydratase
FOC89_RS18400	COG1363	Peptidase, m42
FOC89_RS18460	COG0601	transmembrane transport
FOC89_RS18465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC89_RS18470	COG0444	Belongs to the ABC transporter superfamily
FOC89_RS18475	COG4608	Belongs to the ABC transporter superfamily
FOC89_RS18490	COG0477	Major facilitator Superfamily
FOC89_RS18495	COG3290	protein histidine kinase activity
FOC89_RS18500	COG4565	transcriptional regulatory protein
FOC89_RS18505	COG3181	Tripartite tricarboxylate transporter family receptor
FOC89_RS18535	COG0419	ATPase involved in DNA repair
FOC89_RS18545	COG1104	cysteine desulfurase activity
FOC89_RS18580	COG4978	Transcriptional regulator
FOC89_RS18580	COG0789	Transcriptional regulator
FOC89_RS18595	COG0305	Participates in initiation and elongation during chromosome replication
FOC89_RS18620	COG0477	Major facilitator Superfamily
FOC89_RS18695	COG1183	phosphatidylcholine synthase activity
FOC89_RS18725	COG2376	Dihydroxyacetone kinase
FOC89_RS18735	COG2376	Dihydroxyacetone kinase
FOC89_RS18750	COG3437	response regulator, receiver
FOC89_RS18750	COG2770	Histidine kinase
FOC89_RS18800	COG3237	CsbD-like
FOC89_RS18825	COG1191	sigma factor activity
FOC89_RS18835	COG2208	phosphoserine phosphatase activity
FOC89_RS18840	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC89_RS18845	COG2205	protein histidine kinase activity
FOC89_RS18845	COG2198	Histidine kinase
FOC89_RS18845	COG0784	Response regulator, receiver
FOC89_RS18845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC89_RS18905	COG0420	3'-5' exonuclease activity
FOC89_RS18910	COG4717	serine-type aminopeptidase activity
FOC89_RS18930	COG5444	nuclease activity
FOC89_RS18945	COG0346	lactoylglutathione lyase activity
FOC89_RS18950	COG0346	lactoylglutathione lyase activity
FOC89_RS18955	COG0457	Tetratricopeptide repeat
FOC89_RS18965	COG2267	carboxylic ester hydrolase activity
FOC89_RS18985	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC89_RS18990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC89_RS19000	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC89_RS19025	COG0772	Belongs to the SEDS family
FOC89_RS19040	COG0477	Major facilitator Superfamily
FOC89_RS19045	COG0477	Major facilitator Superfamily
FOC89_RS19055	COG3973	AAA domain
FOC89_RS19060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC89_RS19080	COG4980	gas vesicle protein
FOC89_RS19085	COG0537	adenosine 5'-monophosphoramidase activity
FOC89_RS19090	COG1131	(ABC) transporter
FOC89_RS19095	COG4473	ABC transporter
FOC89_RS19150	COG1309	transcriptional regulator
FOC89_RS19160	COG3402	PFAM membrane-flanked domain
FOC89_RS19165	COG3428	Bacterial PH domain
FOC89_RS19205	COG3402	PFAM membrane-flanked domain
FOC89_RS19210	COG3428	Bacterial PH domain
FOC89_RS19215	COG2329	Antibiotic biosynthesis monooxygenase
FOC89_RS19220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC89_RS19260	COG1309	transcriptional regulator
FOC89_RS19265	COG1511	domain protein
FOC89_RS19285	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FOC89_RS19295	COG2378	regulation of single-species biofilm formation
FOC89_RS19300	COG1609	Transcriptional regulator
FOC89_RS19310	COG1234	tRNA 3'-trailer cleavage
FOC89_RS19315	COG0095	Lipoate-protein ligase
FOC89_RS19325	COG0318	PFAM AMP-dependent synthetase and ligase
FOC89_RS19375	COG1408	metallophosphoesterase
FOC89_RS19385	COG1078	dGTPase activity
FOC89_RS19395	COG1595	DNA-templated transcription, initiation
FOC89_RS19400	COG2207	Transcriptional regulator
FOC89_RS19400	COG3708	Transcriptional regulator
FOC89_RS19415	COG2205	protein histidine kinase activity
FOC89_RS19420	COG0745	RESPONSE REGULATOR receiver
FOC89_RS19445	COG0501	Belongs to the peptidase M48B family
FOC89_RS19450	COG0840	transmembrane signaling receptor activity
FOC89_RS19455	COG0697	spore germination
FOC89_RS19475	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC89_RS19480	COG2224	Isocitrate lyase
FOC89_RS19505	COG4903	ComK protein
FOC89_RS19510	COG0398	Pfam SNARE associated Golgi protein
FOC89_RS19570	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC89_RS19595	COG0367	asparagine synthase
FOC89_RS19605	COG0753	catalase activity
FOC89_RS19610	COG0004	ammonium transporteR
FOC89_RS19630	COG2996	Protein conserved in bacteria
FOC89_RS19640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC89_RS19650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC89_RS19665	COG0561	phosphatase activity
FOC89_RS19675	COG0542	response to heat
FOC89_RS19685	COG2267	carboxylic ester hydrolase activity
FOC89_RS19700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC89_RS19705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC89_RS19710	COG5504	Zn-dependent protease
FOC89_RS19720	COG0180	Tryptophanyl-tRNA synthetase
FOC89_RS19730	COG4166	transmembrane transport
FOC89_RS19735	COG0601	transmembrane transport
FOC89_RS19740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC89_RS19745	COG0444	Belongs to the ABC transporter superfamily
FOC89_RS19750	COG4608	Belongs to the ABC transporter superfamily
FOC89_RS19755	COG0534	Mate efflux family protein
FOC89_RS19760	COG4166	transmembrane transport
FOC89_RS19775	COG0861	Integral membrane protein TerC family
FOC89_RS19780	COG4862	establishment of competence for transformation
FOC89_RS19785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC89_RS19795	COG1164	Oligoendopeptidase f
FOC89_RS19810	COG2346	COG2346, Truncated hemoglobins
FOC89_RS19815	COG4116	CYTH
FOC89_RS19825	COG2357	RelA SpoT domain protein
FOC89_RS19835	COG0564	pseudouridine synthase activity
FOC89_RS19850	COG0772	Belongs to the SEDS family
FOC89_RS19855	COG1216	Glycosyl transferase, family 2
FOC89_RS19855	COG0463	Glycosyl transferase, family 2
FOC89_RS19875	COG0457	Tetratricopeptide repeat
FOC89_RS19875	COG0463	Glycosyl transferase, family 2
FOC89_RS19895	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC89_RS19910	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC89_RS19955	COG2153	protein acetylation
FOC89_RS19965	COG2382	esterase
FOC89_RS19980	COG5492	domain, Protein
FOC89_RS19985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC89_RS19995	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC89_RS19995	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC89_RS20030	COG1620	l-lactate permease
FOC89_RS20035	COG5634	Uncharacterized conserved protein (DUF2278)
FOC89_RS20090	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC89_RS20100	COG1476	TRANSCRIPTIONal
FOC89_RS20155	COG2226	methyltransferase
FOC89_RS20165	COG1686	Belongs to the peptidase S11 family
FOC89_RS20170	COG0681	Belongs to the peptidase S26 family
FOC89_RS20205	COG1012	belongs to the aldehyde dehydrogenase family
FOC89_RS20215	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC89_RS20220	COG1177	transmembrane transport
FOC89_RS20225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC89_RS20235	COG2409	Drug exporters of the RND superfamily
FOC89_RS20245	COG0564	pseudouridine synthase activity
FOC89_RS20255	COG2340	Cysteine-rich secretory protein family
FOC89_RS20260	COG0247	lactate metabolic process
FOC89_RS20265	COG0277	FAD linked oxidase domain protein
FOC89_RS20270	COG3835	regulator
FOC89_RS20280	COG0745	RESPONSE REGULATOR receiver
FOC89_RS20285	COG5002	protein histidine kinase activity
FOC89_RS20290	COG2186	Transcriptional regulator
FOC89_RS20310	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOC89_RS20320	COG2116	formate transmembrane transporter activity
FOC89_RS20325	COG0861	Integral membrane protein TerC family
FOC89_RS20330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC89_RS20340	COG2030	dehydratase
FOC89_RS20360	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS20365	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOC89_RS20375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC89_RS20390	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC89_RS20395	COG3842	ATPase activity
FOC89_RS20420	COG1349	DNA-binding transcription factor activity
FOC89_RS20430	COG0235	Class ii aldolase
FOC89_RS20440	COG2861	carbohydrate metabolic process
FOC89_RS20450	COG3852	Histidine kinase
FOC89_RS20455	COG1846	Transcriptional regulator
FOC89_RS20465	COG2318	DinB family
FOC89_RS20470	COG5002	protein histidine kinase activity
FOC89_RS20480	COG0720	synthase
FOC89_RS20495	COG4873	Protein conserved in bacteria
FOC89_RS20525	COG1780	Probably involved in ribonucleotide reductase function
FOC89_RS20545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC89_RS20550	COG1725	Transcriptional regulator
FOC89_RS20555	COG1131	(ABC) transporter
FOC89_RS20565	COG1131	(ABC) transporter
FOC89_RS20570	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC89_RS20575	COG1266	CAAX protease self-immunity
FOC89_RS20585	COG1522	sequence-specific DNA binding
FOC89_RS20595	COG1335	isochorismatase
FOC89_RS20605	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC89_RS20610	COG2070	2-Nitropropane dioxygenase
FOC89_RS20615	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC89_RS20625	COG1696	Membrane protein involved in D-alanine export
FOC89_RS20650	COG0716	FMN binding
FOC89_RS20665	COG3173	Aminoglycoside phosphotransferase
FOC89_RS20685	COG0534	Mate efflux family protein
FOC89_RS20690	COG1968	undecaprenyl-diphosphatase activity
FOC89_RS20705	COG1846	Transcriptional regulator
FOC89_RS20715	COG1301	dicarboxylic acid transport
FOC89_RS20720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC89_RS20725	COG4709	membrane
FOC89_RS20730	COG3874	Sporulation protein YtfJ
FOC89_RS20750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC89_RS20755	COG0028	Belongs to the TPP enzyme family
FOC89_RS20760	COG0440	acetolactate synthase activity
FOC89_RS20765	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC89_RS20775	COG0473	3-isopropylmalate dehydrogenase activity
FOC89_RS20835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC89_RS20850	COG1183	phosphatidylcholine synthase activity
FOC89_RS20855	COG1368	sulfuric ester hydrolase activity
FOC89_RS20865	COG0019	diaminopimelate decarboxylase activity
FOC89_RS20885	COG0529	Catalyzes the synthesis of activated sulfate
FOC89_RS20890	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC89_RS20910	COG1648	precorrin-2 dehydrogenase activity
FOC89_RS20915	COG0733	neurotransmitter:sodium symporter activity
FOC89_RS20935	COG1757	Na H antiporter
FOC89_RS20950	COG4758	membrane
FOC89_RS20955	COG4585	Histidine kinase
FOC89_RS20960	COG2197	response regulator
FOC89_RS20970	COG1114	Component of the transport system for branched-chain amino acids
FOC89_RS20980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC89_RS21020	COG0730	response to heat
FOC89_RS21025	COG0306	phosphate transporter
FOC89_RS21030	COG1392	Phosphate transport regulator
FOC89_RS21035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC89_RS21050	COG3852	Histidine kinase
FOC89_RS21055	COG1801	Protein of unknown function DUF72
FOC89_RS21065	COG0582	viral genome integration into host DNA
FOC89_RS21070	COG5002	protein histidine kinase activity
FOC89_RS21090	COG0392	lysyltransferase activity
FOC89_RS21090	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOC89_RS21105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC89_RS21110	COG1686	Belongs to the peptidase S11 family
FOC89_RS21115	COG2715	membrane protein required for spore maturation
FOC89_RS21120	COG0700	Nucleoside recognition
FOC89_RS21125	COG1187	pseudouridine synthase activity
FOC89_RS21135	COG1333	cytochrome c biogenesis protein
FOC89_RS21140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC89_RS21145	COG0745	RESPONSE REGULATOR receiver
FOC89_RS21150	COG5002	protein histidine kinase activity
FOC89_RS21155	COG2096	Adenosyltransferase
FOC89_RS21160	COG4942	peptidase
FOC89_RS21170	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOC89_RS21175	COG1141	Ferredoxin
FOC89_RS21185	COG0514	ATP-dependent DNA helicase (RecQ)
FOC89_RS21190	COG1266	CAAX protease self-immunity
FOC89_RS21200	COG1408	metallophosphoesterase
FOC89_RS21210	COG4862	establishment of competence for transformation
FOC89_RS21215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC89_RS21235	COG0492	ferredoxin-NADP+ reductase activity
FOC89_RS21310	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC89_RS21325	COG0142	geranyltranstransferase activity
FOC89_RS21335	COG0142	geranyltranstransferase activity
FOC89_RS21355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC89_RS21360	COG0457	Tetratricopeptide repeat
FOC89_RS21380	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOC89_RS21390	COG4347	Protein of unknown function (DUF1405)
FOC89_RS21405	COG2738	Putative neutral zinc metallopeptidase
FOC89_RS21415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC89_RS21420	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC89_RS21435	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC89_RS21440	COG0438	transferase activity, transferring glycosyl groups
FOC89_RS21475	COG1199	ATP-dependent helicase activity
FOC89_RS21475	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC89_RS21495	COG3935	DnaD domain protein
FOC89_RS21500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC89_RS21510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC89_RS21510	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC89_RS21570	COG0116	Belongs to the methyltransferase superfamily
FOC89_RS21580	COG1199	ATP-dependent helicase activity
FOC89_RS21585	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC89_RS21595	COG3173	Aminoglycoside phosphotransferase
FOC89_RS21600	COG0024	Methionine aminopeptidase
FOC89_RS21610	COG2233	PERMEase
FOC89_RS21615	COG2311	Membrane
FOC89_RS21620	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC89_RS21630	COG0456	acetyltransferase
FOC89_RS21665	COG0754	glutathionylspermidine amidase activity
FOC89_RS21680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC89_RS21705	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC89_RS21720	COG1215	transferase activity, transferring glycosyl groups
FOC89_RS21725	COG0438	transferase activity, transferring glycosyl groups
FOC89_RS21740	COG0454	-acetyltransferase
FOC89_RS21760	COG0328	RNA-DNA hybrid ribonuclease activity
FOC89_RS21795	COG3403	YqcI/YcgG family
FOC89_RS21800	COG1280	lysine exporter protein (LysE YggA)
FOC89_RS21815	COG3162	membrane
FOC89_RS21820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC89_RS21825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC89_RS21835	COG0475	glutathione-regulated potassium exporter activity
FOC89_RS21840	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC89_RS21845	COG4978	Transcriptional regulator
FOC89_RS21845	COG0789	Transcriptional regulator
FOC89_RS21855	COG2323	membrane
FOC89_RS21860	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC89_RS21915	COG1923	regulation of RNA biosynthetic process
FOC89_RS21925	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC89_RS21930	COG1360	Flagellar Motor Protein
FOC89_RS21935	COG2201	protein-glutamate methylesterase activity
FOC89_RS21940	COG0643	Histidine kinase
FOC89_RS21940	COG2198	Histidine kinase
FOC89_RS21945	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC89_RS21945	COG1776	CheC inhibitor of MCP methylation
FOC89_RS21960	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC89_RS21980	COG1256	bacterial-type flagellum assembly
FOC89_RS21985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC89_RS21990	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOC89_RS22005	COG1815	bacterial-type flagellum-dependent cell motility
FOC89_RS22010	COG1558	bacterial-type flagellum-dependent cell motility
FOC89_RS22020	COG1766	The M ring may be actively involved in energy transduction
FOC89_RS22025	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC89_RS22035	COG1157	protein secretion by the type III secretion system
FOC89_RS22070	COG0835	chemotaxis
FOC89_RS22070	COG0784	Response regulator, receiver
FOC89_RS22080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC89_RS22085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC89_RS22090	COG0741	lytic transglycosylase activity
FOC89_RS22100	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC89_RS22105	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC89_RS22105	COG1776	CheC inhibitor of MCP methylation
FOC89_RS22115	COG1338	Plays a role in the flagellum-specific transport system
FOC89_RS22120	COG1987	bacterial-type flagellum assembly
FOC89_RS22130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC89_RS22135	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC89_RS22140	COG1419	protein localization to endoplasmic reticulum
FOC89_RS22145	COG4786	Flagellar basal body rod
FOC89_RS22150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC89_RS22185	COG2329	Antibiotic biosynthesis monooxygenase
FOC89_RS22210	COG0583	DNA-binding transcription factor activity
FOC89_RS22215	COG3842	ATPase activity
FOC89_RS22220	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC89_RS22230	COG1234	tRNA 3'-trailer cleavage
FOC89_RS22260	COG1686	Belongs to the peptidase S11 family
FOC89_RS22290	COG1846	Transcriptional regulator
FOC89_RS22300	COG0367	asparagine synthase
FOC89_RS22330	COG1802	Transcriptional regulator
FOC89_RS22335	COG0697	spore germination
FOC89_RS22340	COG0523	cobalamin synthesis protein
FOC89_RS22345	COG0701	Predicted permease
FOC89_RS22355	COG1216	Glycosyl transferase, family 2
FOC89_RS22355	COG0438	transferase activity, transferring glycosyl groups
FOC89_RS22360	COG1757	Na H antiporter
FOC89_RS22365	COG0789	Transcriptional regulator
FOC89_RS22375	COG0114	fumarate hydratase activity
FOC89_RS22395	COG0534	Mate efflux family protein
FOC89_RS22400	COG3340	Belongs to the peptidase S51 family
FOC89_RS22420	COG0785	Cytochrome C biogenesis protein
FOC89_RS22450	COG2733	membrane
FOC89_RS22485	COG1131	(ABC) transporter
FOC89_RS22500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC89_RS22505	COG0528	UMP kinase activity
FOC89_RS22515	COG1027	Aspartate ammonia-lyase
FOC89_RS22520	COG0281	malic enzyme
FOC89_RS22525	COG4191	Histidine kinase
FOC89_RS22530	COG0784	Response regulator, receiver
FOC89_RS22535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC89_RS22590	COG1051	belongs to the nudix hydrolase family
FOC89_RS22595	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC89_RS22605	COG2814	Major facilitator Superfamily
FOC89_RS22620	COG1966	Carbon starvation protein
FOC89_RS22630	COG0477	Major facilitator Superfamily
FOC89_RS22635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC89_RS22645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC89_RS22650	COG4166	transmembrane transport
FOC89_RS22655	COG2223	nitrite transmembrane transporter activity
FOC89_RS22660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC89_RS22675	COG2244	polysaccharide biosynthetic process
FOC89_RS22680	COG0733	neurotransmitter:sodium symporter activity
FOC89_RS22690	COG5566	PFAM Mor transcription activator
FOC89_RS22695	COG2323	membrane
FOC89_RS22710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC89_RS22720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC89_RS22725	COG0028	Belongs to the TPP enzyme family
FOC89_RS22730	COG0440	acetolactate synthase activity
FOC89_RS22735	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC89_RS22745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC89_RS22770	COG2814	Major facilitator Superfamily
FOC89_RS22775	COG3384	dioxygenase
FOC89_RS22785	COG3279	Response regulator of the LytR AlgR family
FOC89_RS22790	COG0427	acetyl-CoA hydrolase
FOC89_RS22810	COG1073	alpha beta
FOC89_RS22815	COG0582	viral genome integration into host DNA
FOC89_RS22825	COG1396	sequence-specific DNA binding
FOC89_RS22845	COG1396	sequence-specific DNA binding
FOC89_RS22875	COG1484	DNA-dependent DNA replication
FOC89_RS22930	COG0662	Cupin 2, conserved barrel domain protein
FOC89_RS22965	COG0582	viral genome integration into host DNA
FOC89_RS22970	COG2323	membrane
FOC89_RS22980	COG4980	gas vesicle protein
FOC89_RS22980	COG1674	ftsk spoiiie
FOC89_RS23025	COG4626	Terminase
FOC89_RS23025	COG1802	Transcriptional regulator
FOC89_RS23035	COG0740	serine-type endopeptidase activity
FOC89_RS23100	COG4824	toxin secretion phage lysis holin
FOC89_RS23140	COG4166	transmembrane transport
FOC89_RS23170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC89_RS23190	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC89_RS23205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC89_RS23210	COG0531	amino acid
FOC89_RS23235	COG2390	Transcriptional regulator
FOC89_RS23245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC89_RS23250	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC89_RS23260	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC89_RS23285	COG0006	proline dipeptidase activity
FOC89_RS23290	COG2132	Multicopper oxidase
FOC89_RS23325	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC89_RS23330	COG1114	Component of the transport system for branched-chain amino acids
FOC89_RS23340	COG2372	response to copper ion
FOC89_RS23340	COG1276	copper resistance
FOC89_RS23345	COG4549	nuclear export factor GLE1
FOC89_RS23350	COG0697	spore germination
FOC89_RS23355	COG0583	DNA-binding transcription factor activity
FOC89_RS23360	COG1959	2 iron, 2 sulfur cluster binding
FOC89_RS23365	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC89_RS23370	COG0778	Nitroreductase
FOC89_RS23380	COG0628	permease
FOC89_RS23390	COG1231	oxidoreductase activity
FOC89_RS23395	COG0523	cobalamin synthesis protein
FOC89_RS23410	COG0318	PFAM AMP-dependent synthetase and ligase
FOC89_RS23415	COG2030	dehydratase
FOC89_RS23420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC89_RS23430	COG0411	ABC transporter
FOC89_RS23450	COG0583	DNA-binding transcription factor activity
FOC89_RS23460	COG1942	4-Oxalocrotonate Tautomerase
FOC89_RS23480	COG1271	oxidase subunit
FOC89_RS23485	COG1294	oxidase, subunit
FOC89_RS23490	COG4988	ABC transporter
FOC89_RS23495	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC89_RS23510	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC89_RS23515	COG1686	Belongs to the peptidase S11 family
FOC89_RS23530	COG0791	NLP P60 protein
FOC89_RS23530	COG1388	LysM domain
FOC89_RS23540	COG1132	(ABC) transporter
FOC89_RS23545	COG0745	RESPONSE REGULATOR receiver
FOC89_RS23550	COG5002	protein histidine kinase activity
FOC89_RS23560	COG0300	oxidoreductase activity
FOC89_RS23580	COG5658	integral membrane protein
FOC89_RS23595	COG0460	homoserine dehydrogenase
FOC89_RS23620	COG1316	TRANSCRIPTIONal
FOC89_RS23630	COG0745	RESPONSE REGULATOR receiver
FOC89_RS23635	COG5002	protein histidine kinase activity
FOC89_RS23650	COG1285	pathogenesis
FOC89_RS23655	COG1247	-acetyltransferase
FOC89_RS23665	COG4264	IucA IucC family
FOC89_RS23670	COG0318	PFAM AMP-dependent synthetase and ligase
FOC89_RS23685	COG1082	Xylose isomerase domain protein TIM barrel
FOC89_RS23695	COG2814	Major facilitator Superfamily
FOC89_RS23700	COG1279	arginine transmembrane transporter activity
FOC89_RS23710	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC89_RS23745	COG0577	efflux transmembrane transporter activity
FOC89_RS23750	COG2002	toxin-antitoxin pair type II binding
FOC89_RS23765	COG1404	Belongs to the peptidase S8 family
FOC89_RS23770	COG0640	Transcriptional regulator
FOC89_RS23775	COG0667	Aldo Keto reductase
FOC89_RS23780	COG2814	Major facilitator Superfamily
FOC89_RS23805	COG0840	transmembrane signaling receptor activity
FOC89_RS23820	COG3949	Membrane
FOC89_RS23825	COG0783	Belongs to the Dps family
FOC89_RS23840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC89_RS23850	COG1231	oxidoreductase activity
FOC89_RS23860	COG4989	oxidoreductase activity
FOC89_RS23865	COG0523	cobalamin synthesis protein
FOC89_RS23870	COG0456	acetyltransferase
FOC89_RS23930	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC89_RS23930	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC89_RS23940	COG0702	epimerase
FOC89_RS23950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC89_RS23960	COG4166	transmembrane transport
FOC89_RS23975	COG0406	alpha-ribazole phosphatase activity
FOC89_RS23985	COG5337	Spore coat protein CotH
FOC89_RS23990	COG1051	belongs to the nudix hydrolase family
FOC89_RS23995	COG0586	Pfam SNARE associated Golgi protein
FOC89_RS24000	COG2244	polysaccharide biosynthetic process
FOC89_RS24010	COG0701	Predicted permease
FOC89_RS24015	COG3689	TIGRFAM TIGR03943 family protein
FOC89_RS24020	COG1607	acyl-coa hydrolase
FOC89_RS24030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC89_RS24045	COG0702	epimerase
FOC89_RS24050	COG2839	Protein conserved in bacteria
FOC89_RS24055	COG1253	flavin adenine dinucleotide binding
FOC89_RS24070	COG1114	Component of the transport system for branched-chain amino acids
FOC89_RS24075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC89_RS24095	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC89_RS24105	COG1876	peptidase activity
FOC89_RS24115	COG0154	amidase activity
FOC89_RS24120	COG2211	Major facilitator Superfamily
FOC89_RS24140	COG0561	phosphatase activity
FOC89_RS24150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC89_RS24155	COG4106	trans-aconitate 2-methyltransferase activity
FOC89_RS24170	COG1819	glycosyl
FOC89_RS24175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC89_RS24180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC89_RS24210	COG0456	acetyltransferase
FOC89_RS24280	COG3874	Sporulation protein YtfJ
FOC89_RS24305	COG2226	methyltransferase
FOC89_RS24330	COG0346	lactoylglutathione lyase activity
FOC89_RS24340	COG0604	alcohol dehydrogenase
FOC89_RS24345	COG1595	DNA-templated transcription, initiation
FOC89_RS24360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOC89_RS24380	COG0386	Belongs to the glutathione peroxidase family
FOC89_RS24385	COG1305	Transglutaminase-like
FOC89_RS24390	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOC89_RS24395	COG0714	Associated with various cellular activities
FOC89_RS24400	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC89_RS24405	COG1140	nitrate reductase beta subunit
FOC89_RS24410	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC89_RS24415	COG2181	nitrate reductase activity
FOC89_RS24425	COG1959	2 iron, 2 sulfur cluster binding
FOC89_RS24430	COG3118	belongs to the thioredoxin family
FOC89_RS24435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC89_RS24440	COG4918	Iron-sulphur cluster biosynthesis
FOC89_RS24445	COG1764	response to oxidative stress
FOC89_RS24450	COG1335	isochorismatase
FOC89_RS24460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC89_RS24465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC89_RS24470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC89_RS24475	COG0303	'Molybdopterin
FOC89_RS24480	COG0314	molybdopterin synthase activity
FOC89_RS24490	COG2223	nitrite transmembrane transporter activity
FOC89_RS24500	COG1648	precorrin-2 dehydrogenase activity
FOC89_RS24510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC89_RS24510	COG1587	Uroporphyrinogen-III synthase
FOC89_RS24515	COG2146	nitrite reductase [NAD(P)H] activity
FOC89_RS24520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC89_RS24525	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC89_RS24560	COG2359	stage V sporulation protein S
FOC89_RS24585	COG1418	mRNA catabolic process
FOC89_RS24590	COG0488	(ABC) transporter
FOC89_RS24605	COG0629	single-stranded DNA binding
FOC89_RS24610	COG1413	lyase activity
FOC89_RS24625	COG2521	methyltransferase
FOC89_RS24625	COG2136	Putative SAM-dependent methyltransferase
FOC89_RS24630	COG0018	arginyl-trna synthetase
FOC89_RS24670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC89_RS24675	COG0017	Asparaginyl-tRNA synthetase
FOC89_RS24695	COG1674	ftsk spoiiie
FOC89_RS24780	COG1929	Belongs to the glycerate kinase type-1 family
FOC89_RS24785	COG0471	metal ion transport
FOC89_RS24790	COG0745	RESPONSE REGULATOR receiver
FOC89_RS24795	COG5002	protein histidine kinase activity
FOC89_RS24795	COG3850	Histidine kinase
FOC89_RS24810	COG0733	neurotransmitter:sodium symporter activity
FOC89_RS24835	COG2610	gluconate transmembrane transporter activity
FOC89_RS24840	COG1454	alcohol dehydrogenase
FOC89_RS24845	COG1794	racemase activity, acting on amino acids and derivatives
FOC89_RS24855	COG0456	acetyltransferase
FOC89_RS24860	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC89_RS24870	COG1131	(ABC) transporter
FOC89_RS24875	COG4473	ABC transporter
FOC89_RS24885	COG0546	phosphoglycolate phosphatase activity
FOC89_RS24905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC89_RS24920	COG0768	penicillin binding
FOC89_RS24930	COG0204	Acyl-transferase
FOC89_RS24935	COG1272	protein, Hemolysin III
FOC89_RS24945	COG0805	protein transport
FOC89_RS24955	COG1307	EDD domain protein, DegV family
FOC89_RS24960	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC89_RS24965	COG1999	signal sequence binding
FOC89_RS24970	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC89_RS24975	COG0367	asparagine synthase
FOC89_RS24990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC89_RS24995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC89_RS25015	COG1335	isochorismatase
FOC89_RS25020	COG1051	belongs to the nudix hydrolase family
FOC89_RS25025	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC89_RS25030	COG0668	transmembrane transport
FOC89_RS25035	COG4585	Histidine kinase
FOC89_RS25035	COG2203	Gaf domain
FOC89_RS25040	COG2197	response regulator
FOC89_RS25050	COG1064	alcohol dehydrogenase
FOC89_RS25075	COG1070	Carbohydrate kinase
FOC89_RS25080	COG1070	Carbohydrate kinase
FOC89_RS25110	COG0517	IMP dehydrogenase activity
FOC89_RS25110	COG1125	glycine betaine transport
FOC89_RS25115	COG1174	glycine betaine transport
FOC89_RS25150	COG1253	flavin adenine dinucleotide binding
FOC89_RS25155	COG1012	belongs to the aldehyde dehydrogenase family
FOC89_RS25160	COG5506	Protein of unknown function (DUF1694)
FOC89_RS25175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC89_RS25180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC89_RS25185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC89_RS25190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC89_RS25195	COG0456	acetyltransferase
FOC89_RS25200	COG3829	transcription factor binding
FOC89_RS25205	COG1509	lysine 2,3-aminomutase activity
FOC89_RS25245	COG4326	sporulation control protein
FOC89_RS25250	COG0671	phosphoesterase, PA-phosphatase related
FOC89_RS25255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC89_RS25260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC89_RS25275	COG5444	nuclease activity
FOC89_RS25355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC89_RS25395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC89_RS25395	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC89_RS25400	COG2814	Major facilitator Superfamily
FOC89_RS25405	COG4841	protein insertion into membrane
FOC89_RS25410	COG0372	Belongs to the citrate synthase family
FOC89_RS25415	COG2079	MmgE PrpD family protein
FOC89_RS25420	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC89_RS25425	COG1960	acyl-CoA dehydrogenase activity
FOC89_RS25430	COG2084	Dehydrogenase
FOC89_RS25440	COG1280	lysine exporter protein (LysE YggA)
FOC89_RS25445	COG1024	Enoyl-CoA hydratase
FOC89_RS25460	COG0420	3'-5' exonuclease activity
FOC89_RS25465	COG0419	ATPase involved in DNA repair
FOC89_RS25480	COG2223	nitrite transmembrane transporter activity
FOC89_RS25485	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS25490	COG1169	isochorismate synthase
FOC89_RS25495	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOC89_RS25500	COG3433	isochorismatase activity
FOC89_RS25500	COG1535	isochorismatase
FOC89_RS25505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC89_RS25510	COG3251	PFAM MbtH domain protein
FOC89_RS25515	COG2814	Major facilitator Superfamily
FOC89_RS25530	COG0776	regulation of translation
FOC89_RS25540	COG2318	DinB family
FOC89_RS25550	COG1115	amino acid carrier protein
FOC89_RS25565	COG2329	Antibiotic biosynthesis monooxygenase
FOC89_RS25570	COG1187	pseudouridine synthase activity
FOC89_RS25575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC89_RS25580	COG1136	(ABC) transporter
FOC89_RS25590	COG0596	Alpha beta hydrolase
FOC89_RS25610	COG2226	methyltransferase
FOC89_RS25645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC89_RS25680	COG1247	-acetyltransferase
FOC89_RS25720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC89_RS25730	COG1278	Cold shock
FOC89_RS25745	COG0010	Belongs to the arginase family
FOC89_RS25750	COG0561	phosphatase activity
FOC89_RS25795	COG0583	DNA-binding transcription factor activity
FOC89_RS25800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC89_RS25815	COG0583	DNA-binding transcription factor activity
FOC89_RS25820	COG2258	MOSC domain
FOC89_RS25835	COG1132	(ABC) transporter
FOC89_RS25840	COG1132	(ABC) transporter
FOC89_RS25860	COG1396	sequence-specific DNA binding
FOC89_RS25890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC89_RS25900	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FOC89_RS25905	COG1595	DNA-templated transcription, initiation
FOC89_RS25935	COG1649	PFAM Uncharacterised BCR, COG1649
FOC89_RS25960	COG2971	BadF BadG BcrA BcrD
FOC89_RS25970	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC89_RS26005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC89_RS26100	COG0582	viral genome integration into host DNA
FOC89_RS26120	COG0577	efflux transmembrane transporter activity
FOC89_RS26120	COG1136	(ABC) transporter
FOC89_RS26125	COG3615	Tellurite resistance protein tehB
FOC89_RS26125	COG0500	methyltransferase
FOC89_RS26140	COG3961	Belongs to the TPP enzyme family
FOC89_RS26145	COG1846	Transcriptional regulator
FOC89_RS26175	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC89_RS26190	COG1595	DNA-templated transcription, initiation
FOC89_RS26200	COG0768	penicillin binding
FOC89_RS26210	COG2367	Beta-lactamase
FOC89_RS26215	COG0671	phosphoesterase, PA-phosphatase related
FOC89_RS26220	COG1609	Transcriptional regulator
FOC89_RS26225	COG2814	Major facilitator Superfamily
FOC89_RS26230	COG0673	inositol 2-dehydrogenase activity
FOC89_RS26260	COG3718	enzyme involved in inositol metabolism
FOC89_RS26275	COG0737	Belongs to the 5'-nucleotidase family
FOC89_RS26285	COG0457	Tetratricopeptide repeat
FOC89_RS26290	COG1476	TRANSCRIPTIONal
FOC89_RS26305	COG1876	peptidase activity
FOC89_RS26325	COG1309	transcriptional regulator
FOC89_RS26360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC89_RS26375	COG1131	(ABC) transporter
FOC89_RS26385	COG1309	transcriptional regulator
FOC89_RS26400	COG1960	acyl-CoA dehydrogenase activity
FOC89_RS26405	COG0439	Biotin carboxylase
FOC89_RS26410	COG0511	ligase activity, forming carbon-carbon bonds
FOC89_RS26415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC89_RS26420	COG1024	Enoyl-CoA hydratase
FOC89_RS26425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC89_RS26430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC89_RS26440	COG1247	-acetyltransferase
FOC89_RS26445	COG0572	uridine kinase
FOC89_RS26455	COG2318	DinB family
FOC89_RS26460	COG1686	Belongs to the peptidase S11 family
FOC89_RS26485	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC89_RS26505	COG3227	Zinc metalloprotease (Elastase)
FOC89_RS26545	COG2814	Major facilitator Superfamily
FOC89_RS26565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC89_RS26585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC89_RS26600	COG1063	alcohol dehydrogenase
FOC89_RS26620	COG3386	PFAM SMP-30 Gluconolaconase
FOC89_RS26630	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FOC89_RS26635	COG3773	Cell wall hydrolase
FOC89_RS26645	COG0745	RESPONSE REGULATOR receiver
FOC89_RS26650	COG2205	protein histidine kinase activity
FOC89_RS26675	COG1136	(ABC) transporter
FOC89_RS26680	COG0577	efflux transmembrane transporter activity
FOC89_RS26700	COG0460	homoserine dehydrogenase
FOC89_RS26705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC89_RS26715	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC89_RS26780	COG2124	cytochrome p450
FOC89_RS26815	COG0561	phosphatase activity
FOC89_RS26820	COG5002	protein histidine kinase activity
FOC89_RS26830	COG1819	glycosyl
FOC89_RS26835	COG1794	racemase activity, acting on amino acids and derivatives
FOC89_RS26860	COG2205	protein histidine kinase activity
FOC89_RS26875	COG0604	alcohol dehydrogenase
FOC89_RS26890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC89_RS26925	COG0693	protein deglycase activity
FOC89_RS26955	COG2814	Major facilitator Superfamily
FOC89_RS26970	COG0584	glycerophosphoryl diester phosphodiesterase
FOC89_RS26985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC89_RS26990	COG0697	spore germination
FOC89_RS27030	COG2223	nitrite transmembrane transporter activity
FOC89_RS27050	COG0592	DNA-directed DNA polymerase activity
FOC89_RS27055	COG1051	belongs to the nudix hydrolase family
FOC89_RS27090	COG3878	Protein conserved in bacteria
FOC89_RS27110	COG4667	esterase of the alpha-beta hydrolase superfamily
FOC89_RS27135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC89_RS27150	COG0322	excinuclease ABC activity
FOC89_RS27190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC89_RS27215	COG1011	Hydrolase
FOC89_RS27230	COG1073	alpha beta
FOC89_RS27240	COG0076	glutamate decarboxylase activity
FOC89_RS27255	COG1523	belongs to the glycosyl hydrolase 13 family
FOC89_RS27260	COG3227	Zinc metalloprotease (Elastase)
FOC89_RS27280	COG0201	protein transport
FOC89_RS27290	COG0697	spore germination
FOC89_RS27295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC89_RS27335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC89_RS27350	COG2959	enzyme of heme biosynthesis
FOC89_RS27385	COG1309	transcriptional regulator
FOC89_RS27415	COG3284	Transcriptional regulator
FOC89_RS27435	COG1349	DNA-binding transcription factor activity
FOC89_RS27455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC89_RS27460	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC89_RS27465	COG0022	dehydrogenase e1 component
FOC89_RS27470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC89_RS27480	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS27485	COG0456	acetyltransferase
FOC89_RS27485	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC89_RS27490	COG0572	uridine kinase
FOC89_RS27520	COG4176	ABC-type proline glycine betaine transport system permease component
FOC89_RS27525	COG0517	IMP dehydrogenase activity
FOC89_RS27525	COG4175	Glycine betaine
FOC89_RS27555	COG2153	protein acetylation
FOC89_RS27560	COG3397	chitin binding
FOC89_RS27575	COG2205	protein histidine kinase activity
FOC89_RS27580	COG2226	methyltransferase
FOC89_RS27605	COG2333	competence protein COMEC
FOC89_RS27605	COG0658	competence protein
FOC89_RS27655	COG3973	AAA domain
FOC89_RS27670	COG2105	PFAM AIG2 family protein
FOC89_RS27675	COG0514	ATP-dependent DNA helicase (RecQ)
FOC89_RS27695	COG4637	Psort location Cytoplasmic, score
FOC89_RS27720	COG3397	chitin binding
FOC89_RS27735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC89_RS27740	COG1115	amino acid carrier protein
FOC89_RS27745	COG1012	belongs to the aldehyde dehydrogenase family
FOC89_RS27750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC89_RS27760	COG3938	Belongs to the proline racemase family
FOC89_RS27765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC89_RS27805	COG0586	Pfam SNARE associated Golgi protein
FOC89_RS27820	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC89_RS27825	COG0519	Catalyzes the synthesis of GMP from XMP
FOC89_RS27830	COG4166	transmembrane transport
FOC89_RS27840	COG4948	Mandelate Racemase Muconate Lactonizing
FOC89_RS27885	COG2936	dipeptidyl-peptidase activity
FOC89_RS27890	COG5002	protein histidine kinase activity
FOC89_RS27895	COG0745	RESPONSE REGULATOR receiver
FOC89_RS27930	COG1164	Oligoendopeptidase f
FOC89_RS27940	COG1307	EDD domain protein, DegV family
FOC89_RS27960	COG2814	Major facilitator Superfamily
FOC89_RS27970	COG1664	Polymer-forming cytoskeletal
FOC89_RS27975	COG0789	Transcriptional regulator
FOC89_RS27980	COG4533	DNA binding
FOC89_RS27985	COG0477	Major facilitator Superfamily
FOC89_RS27985	COG2814	Major facilitator Superfamily
FOC89_RS28005	COG2261	transglycosylase associated protein
FOC89_RS28020	COG2226	methyltransferase
FOC89_RS28055	COG0436	Aminotransferase
FOC89_RS28060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC89_RS28065	COG5146	pantothenate kinase activity
FOC89_RS28070	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC89_RS28085	COG1131	(ABC) transporter
FOC89_RS28135	COG0628	permease
FOC89_RS28145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC89_RS28150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC89_RS28155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC89_RS28160	COG1116	anion transmembrane transporter activity
FOC89_RS28200	COG2746	aminoglycoside 3-N-acetyltransferase activity
FOC89_RS28225	COG0697	spore germination
FOC89_RS28230	COG2318	DinB family
FOC89_RS28250	COG4912	Dna alkylation repair
FOC89_RS28270	COG0861	Integral membrane protein TerC family
FOC89_RS28275	COG1368	sulfuric ester hydrolase activity
FOC89_RS28280	COG0488	(ABC) transporter
FOC89_RS28290	COG1033	growth of symbiont in host cell
FOC89_RS28290	COG2409	Drug exporters of the RND superfamily
FOC89_RS28295	COG1309	transcriptional regulator
FOC89_RS28310	COG0287	Prephenate dehydrogenase
FOC89_RS28315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC89_RS28325	COG1605	Chorismate mutase
FOC89_RS28325	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC89_RS28360	COG1388	LysM domain
FOC89_RS28360	COG3584	3D domain protein
FOC89_RS28370	COG2610	gluconate transmembrane transporter activity
FOC89_RS28375	COG1024	Enoyl-CoA hydratase
FOC89_RS28385	COG3829	transcription factor binding
FOC89_RS28385	COG3290	protein histidine kinase activity
FOC89_RS28400	COG1879	ABC-type sugar transport system periplasmic component
FOC89_RS28410	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC89_RS28420	COG2390	Transcriptional regulator
FOC89_RS28425	COG1070	Carbohydrate kinase
FOC89_RS28455	COG2329	Antibiotic biosynthesis monooxygenase
FOC89_RS28475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC89_RS28485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC89_RS28490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC89_RS28505	COG4187	Peptidase family M20/M25/M40
FOC89_RS28510	COG1414	Transcriptional regulator
FOC89_RS28515	COG0833	amino acid
FOC89_RS28520	COG1690	Belongs to the RtcB family
FOC89_RS28525	COG3239	Fatty acid desaturase
FOC89_RS28530	COG1785	Belongs to the alkaline phosphatase family
FOC89_RS28540	COG3655	Transcriptional regulator
FOC89_RS28555	COG4377	Putative membrane peptidase family (DUF2324)
FOC89_RS28565	COG3279	Response regulator of the LytR AlgR family
FOC89_RS28575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC89_RS28580	COG0346	lactoylglutathione lyase activity
FOC89_RS28600	COG0714	Associated with various cellular activities
FOC89_RS28625	COG0463	Glycosyl transferase, family 2
FOC89_RS28640	COG0463	Glycosyl transferase, family 2
FOC89_RS28650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC89_RS28655	COG0753	catalase activity
FOC89_RS28665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC89_RS28690	COG0714	Associated with various cellular activities
FOC89_RS28700	COG0778	Nitroreductase
FOC89_RS28705	COG1846	Transcriptional regulator
FOC89_RS28725	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC89_RS28735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC89_RS28740	COG0824	Thioesterase
FOC89_RS28745	COG0318	PFAM AMP-dependent synthetase and ligase
FOC89_RS28750	COG0183	Belongs to the thiolase family
FOC89_RS28755	COG1024	Enoyl-CoA hydratase
FOC89_RS28760	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC89_RS28765	COG2723	6-phospho-beta-galactosidase activity
FOC89_RS28770	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC89_RS28775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC89_RS28780	COG0588	phosphoglycerate mutase activity
FOC89_RS28790	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC89_RS28800	COG2508	Transcriptional regulator
FOC89_RS28805	COG2814	Major facilitator Superfamily
FOC89_RS28810	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC89_RS28840	COG1725	Transcriptional regulator
FOC89_RS28850	COG1136	(ABC) transporter
FOC89_RS28875	COG2207	Transcriptional regulator
FOC89_RS28880	COG0456	acetyltransferase
FOC89_RS28900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC89_RS28945	COG0730	response to heat
FOC89_RS28955	COG0833	amino acid
FOC89_RS28965	COG4335	DNA alkylation repair
FOC89_RS29030	COG1984	allophanate hydrolase subunit 2
FOC89_RS29035	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC89_RS29040	COG1414	Transcriptional regulator
FOC89_RS29055	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC89_RS29060	COG0640	Transcriptional regulator
FOC89_RS29070	COG1960	acyl-CoA dehydrogenase activity
FOC89_RS29100	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOC89_RS29115	COG0574	Belongs to the PEP-utilizing enzyme family
FOC89_RS29115	COG3848	Pyruvate phosphate dikinase
FOC89_RS29120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC89_RS29135	COG5577	PFAM Coat F domain
FOC89_RS29140	COG3403	YqcI/YcgG family
FOC89_RS29145	COG1280	lysine exporter protein (LysE YggA)
FOC89_RS29150	COG1113	amino acid transport
FOC89_RS29180	COG1063	alcohol dehydrogenase
FOC89_RS29190	COG1027	Aspartate ammonia-lyase
FOC89_RS29195	COG0252	asparaginase activity
FOC89_RS29200	COG1396	sequence-specific DNA binding
FOC89_RS29230	COG5002	protein histidine kinase activity
FOC89_RS29255	COG2207	Transcriptional regulator
FOC89_RS29270	COG0322	excinuclease ABC activity
FOC89_RS29275	COG0531	amino acid
FOC89_RS29280	COG1114	Component of the transport system for branched-chain amino acids
FOC89_RS29285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC89_RS29305	COG0531	amino acid
FOC89_RS29310	COG0697	spore germination
FOC89_RS29315	COG0784	Response regulator, receiver
FOC89_RS29320	COG4191	Histidine kinase
FOC89_RS29325	COG2066	Belongs to the glutaminase family
FOC89_RS29330	COG1115	amino acid carrier protein
FOC89_RS29340	COG0737	Belongs to the 5'-nucleotidase family
FOC89_RS29345	COG0753	catalase activity
FOC89_RS29350	COG2267	carboxylic ester hydrolase activity
FOC89_RS29355	COG1335	isochorismatase
FOC89_RS29360	COG1335	isochorismatase
FOC89_RS29375	COG0583	DNA-binding transcription factor activity
FOC89_RS29380	COG1846	Transcriptional regulator
FOC89_RS29385	COG0598	Magnesium transport protein CorA
FOC89_RS29420	COG0415	Belongs to the DNA photolyase family
FOC89_RS29425	COG0288	reversible hydration of carbon dioxide
FOC89_RS29435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC89_RS29440	COG5609	conserved protein (DUF2294)
FOC89_RS29455	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC89_RS29460	COG2267	carboxylic ester hydrolase activity
FOC89_RS29465	COG4641	Protein conserved in bacteria
FOC89_RS29470	COG1136	(ABC) transporter
FOC89_RS29495	COG0798	PFAM Bile acid sodium symporter
FOC89_RS29500	COG0346	lactoylglutathione lyase activity
FOC89_RS29505	COG0640	Transcriptional regulator
FOC89_RS29525	COG5002	protein histidine kinase activity
FOC89_RS29530	COG0745	RESPONSE REGULATOR receiver
FOC89_RS29535	COG0456	acetyltransferase
FOC89_RS29545	COG3320	Male sterility
FOC89_RS29545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC89_RS29550	COG1309	transcriptional regulator
FOC89_RS29555	COG1028	Short-chain dehydrogenase reductase Sdr
FOC89_RS29560	COG1522	sequence-specific DNA binding
FOC89_RS29575	COG0346	lactoylglutathione lyase activity
FOC89_RS29595	COG2169	Transcriptional regulator
FOC89_RS29640	COG2814	Major facilitator Superfamily
FOC89_RS29665	COG0745	RESPONSE REGULATOR receiver
FOC89_RS29670	COG5002	protein histidine kinase activity
FOC89_RS29670	COG3850	Histidine kinase
FOC89_RS29695	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC89_RS29720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC89_RS29725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC89_RS29735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC89_RS29750	COG2309	aminopeptidase activity
FOC89_RS29760	COG0789	Transcriptional regulator
FOC89_RS29780	COG1136	(ABC) transporter
FOC89_RS29785	COG0577	efflux transmembrane transporter activity
FOC89_RS29800	COG5002	protein histidine kinase activity
FOC89_RS29800	COG3850	Histidine kinase
FOC89_RS29810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC89_RS29815	COG2271	Major facilitator Superfamily
FOC89_RS29820	COG1556	Lactate utilization protein
FOC89_RS29825	COG1139	Iron-sulfur cluster binding protein
FOC89_RS29835	COG0583	DNA-binding transcription factor activity
FOC89_RS29845	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC89_RS29865	COG0738	Major facilitator superfamily
FOC89_RS29870	COG0673	inositol 2-dehydrogenase activity
FOC89_RS29875	COG0561	phosphatase activity
FOC89_RS29880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC89_RS29885	COG1609	Transcriptional regulator
FOC89_RS29890	COG0457	Tetratricopeptide repeat
FOC89_RS29910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC89_RS29935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC89_RS29945	COG0814	amino acid
FOC89_RS29950	COG1760	l-serine dehydratase
FOC89_RS29955	COG1760	l-serine dehydratase
FOC89_RS29965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC89_RS29970	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC89_RS29980	COG1335	isochorismatase
FOC89_RS29985	COG1522	sequence-specific DNA binding
FOC89_RS29990	COG0531	amino acid
FOC89_RS30005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC89_RS30025	COG0662	Cupin 2, conserved barrel domain protein
FOC89_RS30030	COG2207	Transcriptional regulator
FOC89_RS30030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC89_RS30050	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC89_RS30050	COG3409	Peptidoglycan-binding domain 1 protein
FOC89_RS30090	COG0477	Major facilitator Superfamily
FOC89_RS30100	COG1846	Transcriptional regulator
FOC89_RS30105	COG2814	Major facilitator Superfamily
FOC89_RS30120	COG2076	Multidrug Resistance protein
FOC89_RS30125	COG1309	transcriptional regulator
FOC89_RS30135	COG2031	fatty acid transporter
FOC89_RS30145	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC89_RS30180	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates