locus-tag	class	description
BTF1_RS00015	COG2310	stress, protein
BTF1_RS00020	COG2310	stress, protein
BTF1_RS00025	COG2310	stress, protein
BTF1_RS00030	COG0861	Integral membrane protein TerC family
BTF1_RS00040	COG3853	Toxic anion resistance protein (TelA)
BTF1_RS00055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BTF1_RS00065	COG1295	ribonuclease BN
BTF1_RS00070	COG2217	Heavy metal translocating P-type atpase
BTF1_RS00075	COG0697	spore germination
BTF1_RS00085	COG0681	Belongs to the peptidase S26 family
BTF1_RS00095	COG0586	Pfam SNARE associated Golgi protein
BTF1_RS00110	COG3871	stress protein (general stress protein 26)
BTF1_RS00115	COG0387	Pfam Sodium calcium exchanger
BTF1_RS00125	COG0535	radical SAM domain protein
BTF1_RS00145	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BTF1_RS00150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BTF1_RS00170	COG3829	transcription factor binding
BTF1_RS00180	COG0833	amino acid
BTF1_RS00185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTF1_RS00210	COG1263	PTS System
BTF1_RS00210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTF1_RS00215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTF1_RS00230	COG0463	Glycosyl transferase, family 2
BTF1_RS00240	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTF1_RS00240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTF1_RS00245	COG0463	Glycosyl transferase, family 2
BTF1_RS00255	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BTF1_RS00275	COG1228	amidohydrolase
BTF1_RS00280	COG1090	epimerase
BTF1_RS00310	COG1988	membrane-bound metal-dependent
BTF1_RS00315	COG1194	a g-specific adenine glycosylase
BTF1_RS00340	COG1132	(ABC) transporter
BTF1_RS00345	COG4129	membrane
BTF1_RS00350	COG0067	glutamate synthase
BTF1_RS00350	COG0069	glutamate synthase activity
BTF1_RS00350	COG0070	glutamate synthase
BTF1_RS00360	COG4555	ABC transporter
BTF1_RS00380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTF1_RS00385	COG0735	belongs to the Fur family
BTF1_RS00505	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BTF1_RS00530	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BTF1_RS00540	COG2766	serine protein kinase
BTF1_RS00555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTF1_RS00565	COG1585	Membrane protein implicated in regulation of membrane protease activity
BTF1_RS00570	COG2268	Band 7 protein
BTF1_RS00580	COG3290	protein histidine kinase activity
BTF1_RS00585	COG4565	transcriptional regulatory protein
BTF1_RS00590	COG2851	Citrate transporter
BTF1_RS00615	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BTF1_RS00620	COG3842	ATPase activity
BTF1_RS00625	COG1175	transmembrane transport
BTF1_RS00630	COG0395	ABC-type sugar transport system, permease component
BTF1_RS00640	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BTF1_RS00645	COG0745	RESPONSE REGULATOR receiver
BTF1_RS00650	COG5002	protein histidine kinase activity
BTF1_RS00660	COG4990	cell redox homeostasis
BTF1_RS00670	COG3290	protein histidine kinase activity
BTF1_RS00675	COG4565	transcriptional regulatory protein
BTF1_RS00680	COG3493	citrate carrier protein
BTF1_RS00685	COG0281	malic enzyme
BTF1_RS00700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTF1_RS00705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTF1_RS00715	COG5002	protein histidine kinase activity
BTF1_RS00740	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTF1_RS00745	COG3383	formate dehydrogenase (NAD+) activity
BTF1_RS00750	COG2427	Protein of unknown function (DUF1641)
BTF1_RS00765	COG0531	amino acid
BTF1_RS00770	COG0640	Transcriptional regulator
BTF1_RS00775	COG2217	Heavy metal translocating P-type atpase
BTF1_RS00780	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BTF1_RS00790	COG3227	Zinc metalloprotease (Elastase)
BTF1_RS00810	COG2720	vancomycin resistance protein
BTF1_RS00815	COG1316	TRANSCRIPTIONal
BTF1_RS00820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTF1_RS00825	COG0346	lactoylglutathione lyase activity
BTF1_RS00830	COG1253	flavin adenine dinucleotide binding
BTF1_RS00835	COG1027	Aspartate ammonia-lyase
BTF1_RS00840	COG1620	l-lactate permease
BTF1_RS00855	COG3104	oligopeptide transport
BTF1_RS00860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTF1_RS00865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTF1_RS00870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTF1_RS00885	COG0156	8-amino-7-oxononanoate synthase activity
BTF1_RS00890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTF1_RS00900	COG4548	von Willebrand factor, type A
BTF1_RS00905	COG0714	Associated with various cellular activities
BTF1_RS00925	COG0531	amino acid
BTF1_RS00930	COG2188	Transcriptional regulator
BTF1_RS00935	COG1263	PTS System
BTF1_RS00935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTF1_RS00940	COG0366	Alpha amylase catalytic
BTF1_RS00955	COG0697	spore germination
BTF1_RS00960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTF1_RS00965	COG1115	amino acid carrier protein
BTF1_RS00975	COG1126	abc transporter atp-binding protein
BTF1_RS00980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTF1_RS00985	COG0765	amino acid transport
BTF1_RS00990	COG0765	amino acid transport
BTF1_RS00995	COG0833	amino acid
BTF1_RS01010	COG1595	DNA-templated transcription, initiation
BTF1_RS01020	COG2378	regulation of single-species biofilm formation
BTF1_RS01025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BTF1_RS01030	COG5002	protein histidine kinase activity
BTF1_RS01055	COG0659	secondary active sulfate transmembrane transporter activity
BTF1_RS01070	COG2271	Major facilitator Superfamily
BTF1_RS01075	COG1846	Transcriptional regulator
BTF1_RS01080	COG0477	Major facilitator Superfamily
BTF1_RS01085	COG1609	Transcriptional regulator
BTF1_RS01090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTF1_RS01105	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTF1_RS01110	COG1879	ABC-type sugar transport system periplasmic component
BTF1_RS01140	COG1063	alcohol dehydrogenase
BTF1_RS01185	COG0840	transmembrane signaling receptor activity
BTF1_RS01190	COG3584	3D domain protein
BTF1_RS01190	COG3583	domain protein
BTF1_RS01195	COG1476	TRANSCRIPTIONal
BTF1_RS01215	COG3104	oligopeptide transport
BTF1_RS01220	COG1114	Component of the transport system for branched-chain amino acids
BTF1_RS01235	COG1113	amino acid transport
BTF1_RS01240	COG2252	PERMEase
BTF1_RS01255	COG2153	protein acetylation
BTF1_RS01265	COG0569	domain protein
BTF1_RS01265	COG0475	glutathione-regulated potassium exporter activity
BTF1_RS01280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTF1_RS01290	COG0833	amino acid
BTF1_RS01295	COG4990	cell redox homeostasis
BTF1_RS01310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTF1_RS01315	COG0697	spore germination
BTF1_RS01320	COG0531	amino acid
BTF1_RS01330	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTF1_RS01335	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTF1_RS01340	COG1918	ferrous iron import across plasma membrane
BTF1_RS01340	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTF1_RS01345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BTF1_RS01350	COG0573	inorganic phosphate transmembrane transporter activity
BTF1_RS01355	COG0581	inorganic phosphate transmembrane transporter activity
BTF1_RS01365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTF1_RS01485	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BTF1_RS01505	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BTF1_RS01510	COG1116	anion transmembrane transporter activity
BTF1_RS01515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTF1_RS01520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTF1_RS01525	COG0352	thiamine-phosphate diphosphorylase activity
BTF1_RS01530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTF1_RS01535	COG2104	thiamine diphosphate biosynthetic process
BTF1_RS01545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTF1_RS01550	COG0351	phosphomethylpyrimidine kinase
BTF1_RS01590	COG2205	protein histidine kinase activity
BTF1_RS01595	COG2814	Major facilitator Superfamily
BTF1_RS01600	COG1846	Transcriptional regulator
BTF1_RS01615	COG2252	PERMEase
BTF1_RS01620	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS01680	COG0778	Nitroreductase
BTF1_RS01685	COG2719	SpoVR family
BTF1_RS01705	COG1937	Protein conserved in bacteria
BTF1_RS01710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTF1_RS01710	COG0425	Belongs to the sulfur carrier protein TusA family
BTF1_RS01715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF1_RS01715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTF1_RS01720	COG0425	Belongs to the sulfur carrier protein TusA family
BTF1_RS01725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTF1_RS01725	COG0425	Belongs to the sulfur carrier protein TusA family
BTF1_RS01735	COG2210	Belongs to the sulfur carrier protein TusA family
BTF1_RS01740	COG0730	response to heat
BTF1_RS01750	COG1316	TRANSCRIPTIONal
BTF1_RS01755	COG0604	alcohol dehydrogenase
BTF1_RS01760	COG1283	sodium-dependent phosphate transmembrane transporter activity
BTF1_RS01775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTF1_RS01775	COG3711	transcriptional antiterminator
BTF1_RS01780	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTF1_RS01785	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTF1_RS01810	COG3584	3D domain protein
BTF1_RS01810	COG1388	LysM domain
BTF1_RS01815	COG0577	efflux transmembrane transporter activity
BTF1_RS01820	COG1136	(ABC) transporter
BTF1_RS01830	COG5522	Integral membrane protein (intg_mem_TP0381)
BTF1_RS01845	COG1114	Component of the transport system for branched-chain amino acids
BTF1_RS01850	COG3546	catalase activity
BTF1_RS01885	COG0586	Pfam SNARE associated Golgi protein
BTF1_RS01920	COG0531	amino acid
BTF1_RS01925	COG0475	glutathione-regulated potassium exporter activity
BTF1_RS01935	COG1737	Transcriptional regulator
BTF1_RS01945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTF1_RS01945	COG1263	PTS System
BTF1_RS01955	COG2259	Doxx family
BTF1_RS01975	COG1522	sequence-specific DNA binding
BTF1_RS01985	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS01990	COG0789	Transcriptional regulator
BTF1_RS02005	COG1309	transcriptional regulator
BTF1_RS02010	COG2814	Major facilitator Superfamily
BTF1_RS02015	COG1733	regulation of RNA biosynthetic process
BTF1_RS02035	COG0693	protein deglycase activity
BTF1_RS02040	COG0693	protein deglycase activity
BTF1_RS02040	COG0753	catalase activity
BTF1_RS02050	COG0531	amino acid
BTF1_RS02055	COG1012	belongs to the aldehyde dehydrogenase family
BTF1_RS02060	COG1132	(ABC) transporter
BTF1_RS02065	COG1132	(ABC) transporter
BTF1_RS02070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTF1_RS02075	COG0765	amino acid transport
BTF1_RS02080	COG1126	abc transporter atp-binding protein
BTF1_RS02095	COG0189	ligase activity
BTF1_RS02125	COG0028	Belongs to the TPP enzyme family
BTF1_RS02130	COG3527	Alpha-acetolactate decarboxylase
BTF1_RS02145	COG0561	phosphatase activity
BTF1_RS02155	COG3409	Peptidoglycan-binding domain 1 protein
BTF1_RS02155	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTF1_RS02160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTF1_RS02165	COG0318	PFAM AMP-dependent synthetase and ligase
BTF1_RS02175	COG0659	secondary active sulfate transmembrane transporter activity
BTF1_RS02180	COG2244	polysaccharide biosynthetic process
BTF1_RS02200	COG1024	Enoyl-CoA hydratase
BTF1_RS02220	COG1363	Peptidase, m42
BTF1_RS02255	COG0601	transmembrane transport
BTF1_RS02260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTF1_RS02265	COG0444	Belongs to the ABC transporter superfamily
BTF1_RS02270	COG4608	Belongs to the ABC transporter superfamily
BTF1_RS02280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF1_RS02300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTF1_RS02315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTF1_RS02320	COG2814	Major facilitator Superfamily
BTF1_RS02350	COG2801	Transposase and inactivated derivatives
BTF1_RS02380	COG3157	Type VI secretion system effector, Hcp
BTF1_RS02430	COG0477	Major facilitator Superfamily
BTF1_RS02435	COG3290	protein histidine kinase activity
BTF1_RS02440	COG4565	transcriptional regulatory protein
BTF1_RS02445	COG3181	Tripartite tricarboxylate transporter family receptor
BTF1_RS02485	COG0210	DNA helicase
BTF1_RS02505	COG0305	Participates in initiation and elongation during chromosome replication
BTF1_RS02535	COG0477	Major facilitator Superfamily
BTF1_RS02605	COG1073	alpha beta
BTF1_RS02655	COG1183	phosphatidylcholine synthase activity
BTF1_RS02665	COG2814	Major facilitator Superfamily
BTF1_RS02670	COG0640	Transcriptional regulator
BTF1_RS02680	COG2376	Dihydroxyacetone kinase
BTF1_RS02750	COG2373	Large extracellular alpha-helical protein
BTF1_RS02815	COG1191	sigma factor activity
BTF1_RS02825	COG2208	phosphoserine phosphatase activity
BTF1_RS02830	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTF1_RS02875	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BTF1_RS02895	COG0420	3'-5' exonuclease activity
BTF1_RS02900	COG4717	serine-type aminopeptidase activity
BTF1_RS02915	COG1280	lysine exporter protein (LysE YggA)
BTF1_RS02920	COG0346	lactoylglutathione lyase activity
BTF1_RS02925	COG0346	lactoylglutathione lyase activity
BTF1_RS02940	COG2267	carboxylic ester hydrolase activity
BTF1_RS02965	COG2140	Oxalate decarboxylase
BTF1_RS02970	COG3620	sequence-specific DNA binding
BTF1_RS02980	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BTF1_RS02985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BTF1_RS02995	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BTF1_RS03000	COG1695	Transcriptional regulator
BTF1_RS03025	COG3973	AAA domain
BTF1_RS03050	COG4980	gas vesicle protein
BTF1_RS03055	COG0537	adenosine 5'-monophosphoramidase activity
BTF1_RS03060	COG1131	(ABC) transporter
BTF1_RS03065	COG4473	ABC transporter
BTF1_RS03075	COG1309	transcriptional regulator
BTF1_RS03085	COG3402	PFAM membrane-flanked domain
BTF1_RS03090	COG3428	Bacterial PH domain
BTF1_RS03125	COG0697	spore germination
BTF1_RS03130	COG3402	PFAM membrane-flanked domain
BTF1_RS03135	COG3428	Bacterial PH domain
BTF1_RS03140	COG2329	Antibiotic biosynthesis monooxygenase
BTF1_RS03145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTF1_RS03160	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BTF1_RS03185	COG1309	transcriptional regulator
BTF1_RS03190	COG1511	domain protein
BTF1_RS03215	COG1609	Transcriptional regulator
BTF1_RS03225	COG1234	tRNA 3'-trailer cleavage
BTF1_RS03230	COG0095	Lipoate-protein ligase
BTF1_RS03240	COG0318	PFAM AMP-dependent synthetase and ligase
BTF1_RS03295	COG1073	alpha beta
BTF1_RS03300	COG1408	metallophosphoesterase
BTF1_RS03305	COG1078	dGTPase activity
BTF1_RS03315	COG1595	DNA-templated transcription, initiation
BTF1_RS03320	COG2207	Transcriptional regulator
BTF1_RS03320	COG3708	Transcriptional regulator
BTF1_RS03330	COG2205	protein histidine kinase activity
BTF1_RS03335	COG0745	RESPONSE REGULATOR receiver
BTF1_RS03355	COG0501	Belongs to the peptidase M48B family
BTF1_RS03360	COG0840	transmembrane signaling receptor activity
BTF1_RS03370	COG3693	PFAM glycoside hydrolase, family 10
BTF1_RS03380	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BTF1_RS03385	COG2224	Isocitrate lyase
BTF1_RS03400	COG1278	Cold shock
BTF1_RS03415	COG4903	ComK protein
BTF1_RS03420	COG0398	Pfam SNARE associated Golgi protein
BTF1_RS03480	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTF1_RS03505	COG0367	asparagine synthase
BTF1_RS03515	COG0753	catalase activity
BTF1_RS03520	COG0004	ammonium transporteR
BTF1_RS03540	COG2996	Protein conserved in bacteria
BTF1_RS03545	COG3209	COG3209 Rhs family protein
BTF1_RS03595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTF1_RS03610	COG0561	phosphatase activity
BTF1_RS03630	COG2267	carboxylic ester hydrolase activity
BTF1_RS03645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTF1_RS03650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTF1_RS03655	COG5504	Zn-dependent protease
BTF1_RS03670	COG0180	Tryptophanyl-tRNA synthetase
BTF1_RS03680	COG4166	transmembrane transport
BTF1_RS03685	COG0601	transmembrane transport
BTF1_RS03690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTF1_RS03695	COG0444	Belongs to the ABC transporter superfamily
BTF1_RS03700	COG4608	Belongs to the ABC transporter superfamily
BTF1_RS03705	COG0534	Mate efflux family protein
BTF1_RS03710	COG4166	transmembrane transport
BTF1_RS03725	COG0861	Integral membrane protein TerC family
BTF1_RS03735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTF1_RS03745	COG1164	Oligoendopeptidase f
BTF1_RS03755	COG2346	COG2346, Truncated hemoglobins
BTF1_RS03760	COG4116	CYTH
BTF1_RS03770	COG2357	RelA SpoT domain protein
BTF1_RS03780	COG0564	pseudouridine synthase activity
BTF1_RS03795	COG0772	Belongs to the SEDS family
BTF1_RS03800	COG1216	Glycosyl transferase, family 2
BTF1_RS03840	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BTF1_RS03855	COG1091	dTDP-4-dehydrorhamnose reductase activity
BTF1_RS03900	COG2153	protein acetylation
BTF1_RS03910	COG2382	esterase
BTF1_RS03925	COG5492	domain, Protein
BTF1_RS03930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTF1_RS03945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTF1_RS03945	COG0512	Glutamine amidotransferase of anthranilate synthase
BTF1_RS03980	COG1620	l-lactate permease
BTF1_RS03985	COG5634	Uncharacterized conserved protein (DUF2278)
BTF1_RS04040	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTF1_RS04050	COG1476	TRANSCRIPTIONal
BTF1_RS04085	COG4152	abc transporter atp-binding protein
BTF1_RS04090	COG1668	transmembrane transport
BTF1_RS04100	COG2801	Transposase and inactivated derivatives
BTF1_RS04120	COG2226	methyltransferase
BTF1_RS04130	COG1686	Belongs to the peptidase S11 family
BTF1_RS04135	COG0681	Belongs to the peptidase S26 family
BTF1_RS04170	COG1012	belongs to the aldehyde dehydrogenase family
BTF1_RS04180	COG1176	ABC-type spermidine putrescine transport system, permease component I
BTF1_RS04185	COG1177	transmembrane transport
BTF1_RS04195	COG0671	phosphoesterase, PA-phosphatase related
BTF1_RS04200	COG2409	Drug exporters of the RND superfamily
BTF1_RS04210	COG0564	pseudouridine synthase activity
BTF1_RS04220	COG2340	Cysteine-rich secretory protein family
BTF1_RS04225	COG0247	lactate metabolic process
BTF1_RS04230	COG0277	FAD linked oxidase domain protein
BTF1_RS04235	COG3835	regulator
BTF1_RS04245	COG0745	RESPONSE REGULATOR receiver
BTF1_RS04250	COG5002	protein histidine kinase activity
BTF1_RS04255	COG2186	Transcriptional regulator
BTF1_RS04275	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BTF1_RS04285	COG2116	formate transmembrane transporter activity
BTF1_RS04290	COG0861	Integral membrane protein TerC family
BTF1_RS04295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTF1_RS04305	COG2030	dehydratase
BTF1_RS04325	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS04330	COG3243	poly(R)-hydroxyalkanoic acid synthase
BTF1_RS04340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTF1_RS04355	COG1840	ABC-type Fe3 transport system, periplasmic component
BTF1_RS04360	COG3842	ATPase activity
BTF1_RS04385	COG1349	DNA-binding transcription factor activity
BTF1_RS04400	COG0235	Class ii aldolase
BTF1_RS04410	COG2861	carbohydrate metabolic process
BTF1_RS04420	COG3852	Histidine kinase
BTF1_RS04425	COG1846	Transcriptional regulator
BTF1_RS04435	COG2318	DinB family
BTF1_RS04445	COG5002	protein histidine kinase activity
BTF1_RS04455	COG0720	synthase
BTF1_RS04470	COG4873	Protein conserved in bacteria
BTF1_RS04500	COG1780	Probably involved in ribonucleotide reductase function
BTF1_RS04505	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTF1_RS04510	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTF1_RS04515	COG1725	Transcriptional regulator
BTF1_RS04520	COG1131	(ABC) transporter
BTF1_RS04530	COG1131	(ABC) transporter
BTF1_RS04550	COG1522	sequence-specific DNA binding
BTF1_RS04560	COG1335	isochorismatase
BTF1_RS04570	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTF1_RS04575	COG2070	2-Nitropropane dioxygenase
BTF1_RS04580	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BTF1_RS04590	COG1696	Membrane protein involved in D-alanine export
BTF1_RS04615	COG0716	FMN binding
BTF1_RS04670	COG1846	Transcriptional regulator
BTF1_RS04680	COG1301	dicarboxylic acid transport
BTF1_RS04685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTF1_RS04690	COG4709	membrane
BTF1_RS04695	COG3874	Sporulation protein YtfJ
BTF1_RS04715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTF1_RS04720	COG0028	Belongs to the TPP enzyme family
BTF1_RS04725	COG0440	acetolactate synthase activity
BTF1_RS04800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTF1_RS04815	COG1183	phosphatidylcholine synthase activity
BTF1_RS04820	COG1368	sulfuric ester hydrolase activity
BTF1_RS04830	COG0019	diaminopimelate decarboxylase activity
BTF1_RS04850	COG0529	Catalyzes the synthesis of activated sulfate
BTF1_RS04855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTF1_RS04875	COG1648	precorrin-2 dehydrogenase activity
BTF1_RS04880	COG0733	neurotransmitter:sodium symporter activity
BTF1_RS04900	COG1757	Na H antiporter
BTF1_RS04915	COG4758	membrane
BTF1_RS04920	COG4585	Histidine kinase
BTF1_RS04925	COG2197	response regulator
BTF1_RS04935	COG1114	Component of the transport system for branched-chain amino acids
BTF1_RS04985	COG0730	response to heat
BTF1_RS04990	COG0306	phosphate transporter
BTF1_RS04995	COG1392	Phosphate transport regulator
BTF1_RS05000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTF1_RS05015	COG3852	Histidine kinase
BTF1_RS05020	COG1801	Protein of unknown function DUF72
BTF1_RS05030	COG0582	viral genome integration into host DNA
BTF1_RS05035	COG5002	protein histidine kinase activity
BTF1_RS05050	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BTF1_RS05050	COG0392	lysyltransferase activity
BTF1_RS05065	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTF1_RS05070	COG1686	Belongs to the peptidase S11 family
BTF1_RS05075	COG2715	membrane protein required for spore maturation
BTF1_RS05080	COG0700	Nucleoside recognition
BTF1_RS05085	COG1187	pseudouridine synthase activity
BTF1_RS05095	COG1333	cytochrome c biogenesis protein
BTF1_RS05100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTF1_RS05105	COG0745	RESPONSE REGULATOR receiver
BTF1_RS05110	COG5002	protein histidine kinase activity
BTF1_RS05115	COG2096	Adenosyltransferase
BTF1_RS05120	COG4942	peptidase
BTF1_RS05130	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BTF1_RS05135	COG1141	Ferredoxin
BTF1_RS05145	COG0514	ATP-dependent DNA helicase (RecQ)
BTF1_RS05150	COG1266	CAAX protease self-immunity
BTF1_RS05160	COG1408	metallophosphoesterase
BTF1_RS05165	COG0789	Transcriptional regulator
BTF1_RS05175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTF1_RS05195	COG0492	ferredoxin-NADP+ reductase activity
BTF1_RS05200	COG0252	asparaginase activity
BTF1_RS05265	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTF1_RS05280	COG0142	geranyltranstransferase activity
BTF1_RS05290	COG0142	geranyltranstransferase activity
BTF1_RS05315	COG0457	Tetratricopeptide repeat
BTF1_RS05335	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTF1_RS05340	COG2010	Cytochrome c
BTF1_RS05340	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTF1_RS05345	COG4347	Protein of unknown function (DUF1405)
BTF1_RS05360	COG2738	Putative neutral zinc metallopeptidase
BTF1_RS05370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTF1_RS05375	COG1694	Mazg nucleotide pyrophosphohydrolase
BTF1_RS05395	COG0438	transferase activity, transferring glycosyl groups
BTF1_RS05430	COG1199	ATP-dependent helicase activity
BTF1_RS05430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BTF1_RS05450	COG3935	DnaD domain protein
BTF1_RS05455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTF1_RS05465	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTF1_RS05465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTF1_RS05515	COG0116	Belongs to the methyltransferase superfamily
BTF1_RS05525	COG1199	ATP-dependent helicase activity
BTF1_RS05530	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BTF1_RS05540	COG3173	Aminoglycoside phosphotransferase
BTF1_RS05545	COG0024	Methionine aminopeptidase
BTF1_RS05555	COG2233	PERMEase
BTF1_RS05560	COG2311	Membrane
BTF1_RS05565	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTF1_RS05575	COG0456	acetyltransferase
BTF1_RS05600	COG0754	glutathionylspermidine amidase activity
BTF1_RS05615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTF1_RS05630	COG3944	biosynthesis protein
BTF1_RS05640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTF1_RS05655	COG1215	transferase activity, transferring glycosyl groups
BTF1_RS05660	COG0438	transferase activity, transferring glycosyl groups
BTF1_RS05675	COG0454	-acetyltransferase
BTF1_RS05695	COG0328	RNA-DNA hybrid ribonuclease activity
BTF1_RS05730	COG3403	YqcI/YcgG family
BTF1_RS05735	COG1280	lysine exporter protein (LysE YggA)
BTF1_RS05755	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTF1_RS05760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTF1_RS05770	COG0475	glutathione-regulated potassium exporter activity
BTF1_RS05780	COG4978	Transcriptional regulator
BTF1_RS05780	COG0789	Transcriptional regulator
BTF1_RS05790	COG2323	membrane
BTF1_RS05795	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BTF1_RS05830	COG1923	regulation of RNA biosynthetic process
BTF1_RS05840	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BTF1_RS05845	COG1360	Flagellar Motor Protein
BTF1_RS05850	COG2201	protein-glutamate methylesterase activity
BTF1_RS05855	COG0643	Histidine kinase
BTF1_RS05855	COG2198	Histidine kinase
BTF1_RS05860	COG1776	CheC inhibitor of MCP methylation
BTF1_RS05860	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTF1_RS05875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTF1_RS05895	COG1256	bacterial-type flagellum assembly
BTF1_RS05900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTF1_RS05920	COG1815	bacterial-type flagellum-dependent cell motility
BTF1_RS05925	COG1558	bacterial-type flagellum-dependent cell motility
BTF1_RS05935	COG1766	The M ring may be actively involved in energy transduction
BTF1_RS05940	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTF1_RS05950	COG1157	protein secretion by the type III secretion system
BTF1_RS05970	COG1749	Flagellar hook protein flgE
BTF1_RS05985	COG0835	chemotaxis
BTF1_RS05985	COG0784	Response regulator, receiver
BTF1_RS06015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTF1_RS06020	COG0741	lytic transglycosylase activity
BTF1_RS06030	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTF1_RS06035	COG1776	CheC inhibitor of MCP methylation
BTF1_RS06035	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTF1_RS06045	COG1338	Plays a role in the flagellum-specific transport system
BTF1_RS06050	COG1987	bacterial-type flagellum assembly
BTF1_RS06060	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTF1_RS06065	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTF1_RS06070	COG1419	protein localization to endoplasmic reticulum
BTF1_RS06075	COG4786	Flagellar basal body rod
BTF1_RS06080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTF1_RS06085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTF1_RS06115	COG2329	Antibiotic biosynthesis monooxygenase
BTF1_RS06120	COG1215	transferase activity, transferring glycosyl groups
BTF1_RS06145	COG0583	DNA-binding transcription factor activity
BTF1_RS06165	COG1234	tRNA 3'-trailer cleavage
BTF1_RS06195	COG0406	alpha-ribazole phosphatase activity
BTF1_RS06215	COG1846	Transcriptional regulator
BTF1_RS06225	COG0367	asparagine synthase
BTF1_RS06260	COG0523	cobalamin synthesis protein
BTF1_RS06265	COG0701	Predicted permease
BTF1_RS06275	COG0438	transferase activity, transferring glycosyl groups
BTF1_RS06275	COG1216	Glycosyl transferase, family 2
BTF1_RS06280	COG1757	Na H antiporter
BTF1_RS06285	COG0789	Transcriptional regulator
BTF1_RS06315	COG0534	Mate efflux family protein
BTF1_RS06320	COG3340	Belongs to the peptidase S51 family
BTF1_RS06340	COG0785	Cytochrome C biogenesis protein
BTF1_RS06345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTF1_RS06355	COG0457	Tetratricopeptide repeat
BTF1_RS06375	COG2733	membrane
BTF1_RS06410	COG1131	(ABC) transporter
BTF1_RS06425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTF1_RS06430	COG0528	UMP kinase activity
BTF1_RS06440	COG1027	Aspartate ammonia-lyase
BTF1_RS06445	COG0281	malic enzyme
BTF1_RS06450	COG4191	Histidine kinase
BTF1_RS06455	COG0784	Response regulator, receiver
BTF1_RS06460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTF1_RS06510	COG2814	Major facilitator Superfamily
BTF1_RS06525	COG1695	Transcriptional regulator
BTF1_RS06535	COG0477	Major facilitator Superfamily
BTF1_RS06545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTF1_RS06550	COG2223	nitrite transmembrane transporter activity
BTF1_RS06555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTF1_RS06575	COG0733	neurotransmitter:sodium symporter activity
BTF1_RS06585	COG5566	PFAM Mor transcription activator
BTF1_RS06590	COG2323	membrane
BTF1_RS06610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTF1_RS06620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTF1_RS06625	COG0028	Belongs to the TPP enzyme family
BTF1_RS06645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTF1_RS06665	COG2814	Major facilitator Superfamily
BTF1_RS06670	COG3384	dioxygenase
BTF1_RS06685	COG3279	Response regulator of the LytR AlgR family
BTF1_RS06690	COG0427	acetyl-CoA hydrolase
BTF1_RS06710	COG4166	transmembrane transport
BTF1_RS06715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTF1_RS06735	COG1914	H( )-stimulated, divalent metal cation uptake system
BTF1_RS06750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTF1_RS06760	COG0531	amino acid
BTF1_RS06780	COG2309	aminopeptidase activity
BTF1_RS06795	COG0456	acetyltransferase
BTF1_RS06810	COG1309	transcriptional regulator
BTF1_RS06815	COG2390	Transcriptional regulator
BTF1_RS06825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTF1_RS06830	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BTF1_RS06835	COG0295	cytidine deaminase activity
BTF1_RS06870	COG4846	Membrane protein involved in cytochrome C biogenesis
BTF1_RS06880	COG0006	proline dipeptidase activity
BTF1_RS06890	COG2132	Multicopper oxidase
BTF1_RS06900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTF1_RS06920	COG1114	Component of the transport system for branched-chain amino acids
BTF1_RS06930	COG1276	copper resistance
BTF1_RS06930	COG2372	response to copper ion
BTF1_RS06935	COG4549	nuclear export factor GLE1
BTF1_RS06940	COG0697	spore germination
BTF1_RS06945	COG0583	DNA-binding transcription factor activity
BTF1_RS06950	COG1959	2 iron, 2 sulfur cluster binding
BTF1_RS06955	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BTF1_RS06960	COG0778	Nitroreductase
BTF1_RS06975	COG0628	permease
BTF1_RS06985	COG1231	oxidoreductase activity
BTF1_RS06990	COG0523	cobalamin synthesis protein
BTF1_RS07000	COG0411	ABC transporter
BTF1_RS07020	COG0583	DNA-binding transcription factor activity
BTF1_RS07050	COG1271	oxidase subunit
BTF1_RS07055	COG1294	oxidase, subunit
BTF1_RS07060	COG4988	ABC transporter
BTF1_RS07065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BTF1_RS07075	COG1216	Glycosyl transferase, family 2
BTF1_RS07115	COG1686	Belongs to the peptidase S11 family
BTF1_RS07130	COG1388	LysM domain
BTF1_RS07130	COG0791	NLP P60 protein
BTF1_RS07140	COG1132	(ABC) transporter
BTF1_RS07145	COG0745	RESPONSE REGULATOR receiver
BTF1_RS07150	COG5002	protein histidine kinase activity
BTF1_RS07155	COG0300	oxidoreductase activity
BTF1_RS07160	COG4122	O-methyltransferase activity
BTF1_RS07195	COG0460	homoserine dehydrogenase
BTF1_RS07220	COG1316	TRANSCRIPTIONal
BTF1_RS07235	COG1285	pathogenesis
BTF1_RS07240	COG1247	-acetyltransferase
BTF1_RS07260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTF1_RS07270	COG1082	Xylose isomerase domain protein TIM barrel
BTF1_RS07280	COG2814	Major facilitator Superfamily
BTF1_RS07285	COG1279	arginine transmembrane transporter activity
BTF1_RS07290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTF1_RS07300	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTF1_RS07340	COG2002	toxin-antitoxin pair type II binding
BTF1_RS07345	COG1404	Belongs to the peptidase S8 family
BTF1_RS07350	COG0640	Transcriptional regulator
BTF1_RS07355	COG0667	Aldo Keto reductase
BTF1_RS07360	COG2814	Major facilitator Superfamily
BTF1_RS07385	COG0840	transmembrane signaling receptor activity
BTF1_RS07400	COG3949	Membrane
BTF1_RS07405	COG0783	Belongs to the Dps family
BTF1_RS07420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTF1_RS07430	COG1231	oxidoreductase activity
BTF1_RS07435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTF1_RS07440	COG4989	oxidoreductase activity
BTF1_RS07445	COG0523	cobalamin synthesis protein
BTF1_RS07450	COG0456	acetyltransferase
BTF1_RS07455	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTF1_RS07465	COG0702	epimerase
BTF1_RS07475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTF1_RS07485	COG4166	transmembrane transport
BTF1_RS07500	COG0406	alpha-ribazole phosphatase activity
BTF1_RS07510	COG5337	Spore coat protein CotH
BTF1_RS07515	COG1051	belongs to the nudix hydrolase family
BTF1_RS07520	COG0586	Pfam SNARE associated Golgi protein
BTF1_RS07525	COG2244	polysaccharide biosynthetic process
BTF1_RS07535	COG0701	Predicted permease
BTF1_RS07540	COG3689	TIGRFAM TIGR03943 family protein
BTF1_RS07545	COG1607	acyl-coa hydrolase
BTF1_RS07550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTF1_RS07565	COG0702	epimerase
BTF1_RS07570	COG2839	Protein conserved in bacteria
BTF1_RS07575	COG1253	flavin adenine dinucleotide binding
BTF1_RS07600	COG1114	Component of the transport system for branched-chain amino acids
BTF1_RS07605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTF1_RS07620	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTF1_RS07630	COG1876	peptidase activity
BTF1_RS07645	COG2211	Major facilitator Superfamily
BTF1_RS07660	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTF1_RS07670	COG0561	phosphatase activity
BTF1_RS07675	COG1846	Transcriptional regulator
BTF1_RS07680	COG2814	Major facilitator Superfamily
BTF1_RS07690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTF1_RS07695	COG4106	trans-aconitate 2-methyltransferase activity
BTF1_RS07710	COG1819	glycosyl
BTF1_RS07715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTF1_RS07720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTF1_RS07750	COG0456	acetyltransferase
BTF1_RS07900	COG4974	Belongs to the 'phage' integrase family
BTF1_RS07910	COG3874	Sporulation protein YtfJ
BTF1_RS07935	COG2226	methyltransferase
BTF1_RS07955	COG1082	Xylose isomerase domain protein TIM barrel
BTF1_RS07960	COG0346	lactoylglutathione lyase activity
BTF1_RS07970	COG0604	alcohol dehydrogenase
BTF1_RS07975	COG1595	DNA-templated transcription, initiation
BTF1_RS07985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BTF1_RS07995	COG0426	domain, Protein
BTF1_RS07995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTF1_RS08005	COG0386	Belongs to the glutathione peroxidase family
BTF1_RS08010	COG1305	Transglutaminase-like
BTF1_RS08015	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BTF1_RS08020	COG0714	Associated with various cellular activities
BTF1_RS08025	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BTF1_RS08030	COG1140	nitrate reductase beta subunit
BTF1_RS08035	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BTF1_RS08040	COG2181	nitrate reductase activity
BTF1_RS08045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTF1_RS08050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTF1_RS08055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTF1_RS08060	COG0303	'Molybdopterin
BTF1_RS08065	COG0314	molybdopterin synthase activity
BTF1_RS08075	COG2223	nitrite transmembrane transporter activity
BTF1_RS08090	COG1648	precorrin-2 dehydrogenase activity
BTF1_RS08095	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BTF1_RS08100	COG1587	Uroporphyrinogen-III synthase
BTF1_RS08100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BTF1_RS08105	COG2146	nitrite reductase [NAD(P)H] activity
BTF1_RS08110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTF1_RS08115	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BTF1_RS08150	COG2359	stage V sporulation protein S
BTF1_RS08165	COG0457	Tetratricopeptide repeat
BTF1_RS08180	COG1418	mRNA catabolic process
BTF1_RS08185	COG0488	(ABC) transporter
BTF1_RS08200	COG0629	single-stranded DNA binding
BTF1_RS08210	COG1413	lyase activity
BTF1_RS08225	COG2136	Putative SAM-dependent methyltransferase
BTF1_RS08225	COG2521	methyltransferase
BTF1_RS08230	COG0018	arginyl-trna synthetase
BTF1_RS08275	COG0017	Asparaginyl-tRNA synthetase
BTF1_RS08280	COG0733	neurotransmitter:sodium symporter activity
BTF1_RS08305	COG2610	gluconate transmembrane transporter activity
BTF1_RS08315	COG1794	racemase activity, acting on amino acids and derivatives
BTF1_RS08325	COG0456	acetyltransferase
BTF1_RS08330	COG3655	Transcriptional regulator
BTF1_RS08335	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTF1_RS08345	COG1131	(ABC) transporter
BTF1_RS08360	COG0546	phosphoglycolate phosphatase activity
BTF1_RS08390	COG0768	penicillin binding
BTF1_RS08400	COG0204	Acyl-transferase
BTF1_RS08405	COG1272	protein, Hemolysin III
BTF1_RS08415	COG0805	protein transport
BTF1_RS08425	COG1307	EDD domain protein, DegV family
BTF1_RS08435	COG1999	signal sequence binding
BTF1_RS08440	COG0071	Belongs to the small heat shock protein (HSP20) family
BTF1_RS08445	COG0367	asparagine synthase
BTF1_RS08460	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTF1_RS08465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTF1_RS08470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTF1_RS08490	COG1335	isochorismatase
BTF1_RS08495	COG1051	belongs to the nudix hydrolase family
BTF1_RS08500	COG0668	transmembrane transport
BTF1_RS08505	COG2203	Gaf domain
BTF1_RS08505	COG4585	Histidine kinase
BTF1_RS08510	COG2197	response regulator
BTF1_RS08515	COG1737	Transcriptional regulator
BTF1_RS08520	COG0384	phenazine biosynthesis protein PhzF
BTF1_RS08525	COG1064	alcohol dehydrogenase
BTF1_RS08540	COG1070	Carbohydrate kinase
BTF1_RS08550	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BTF1_RS08585	COG0517	IMP dehydrogenase activity
BTF1_RS08585	COG1125	glycine betaine transport
BTF1_RS08590	COG1174	glycine betaine transport
BTF1_RS08625	COG1253	flavin adenine dinucleotide binding
BTF1_RS08630	COG1012	belongs to the aldehyde dehydrogenase family
BTF1_RS08635	COG5506	Protein of unknown function (DUF1694)
BTF1_RS08650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTF1_RS08655	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BTF1_RS08660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BTF1_RS08665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTF1_RS08670	COG0456	acetyltransferase
BTF1_RS08675	COG3829	transcription factor binding
BTF1_RS08680	COG1509	lysine 2,3-aminomutase activity
BTF1_RS08710	COG3064	Membrane
BTF1_RS08710	COG4991	sh3 domain protein
BTF1_RS08710	COG0515	serine threonine protein kinase
BTF1_RS08720	COG0671	phosphoesterase, PA-phosphatase related
BTF1_RS08725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTF1_RS08730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTF1_RS08805	COG0300	oxidoreductase activity
BTF1_RS08825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTF1_RS08825	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTF1_RS08835	COG2814	Major facilitator Superfamily
BTF1_RS08840	COG4841	protein insertion into membrane
BTF1_RS08845	COG0372	Belongs to the citrate synthase family
BTF1_RS08850	COG2079	MmgE PrpD family protein
BTF1_RS08855	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BTF1_RS08860	COG1960	acyl-CoA dehydrogenase activity
BTF1_RS08865	COG2084	Dehydrogenase
BTF1_RS08875	COG1280	lysine exporter protein (LysE YggA)
BTF1_RS08880	COG1024	Enoyl-CoA hydratase
BTF1_RS08895	COG0420	3'-5' exonuclease activity
BTF1_RS08900	COG0419	ATPase involved in DNA repair
BTF1_RS08920	COG2223	nitrite transmembrane transporter activity
BTF1_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS08930	COG1169	isochorismate synthase
BTF1_RS08935	COG1021	2,3-dihydroxybenzoate-AMP ligase
BTF1_RS08940	COG3433	isochorismatase activity
BTF1_RS08940	COG1535	isochorismatase
BTF1_RS08945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BTF1_RS08950	COG3251	PFAM MbtH domain protein
BTF1_RS08955	COG2814	Major facilitator Superfamily
BTF1_RS08970	COG0776	regulation of translation
BTF1_RS08980	COG2318	DinB family
BTF1_RS08990	COG1115	amino acid carrier protein
BTF1_RS09010	COG1187	pseudouridine synthase activity
BTF1_RS09015	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTF1_RS09020	COG1136	(ABC) transporter
BTF1_RS09060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTF1_RS09080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF1_RS09115	COG1247	-acetyltransferase
BTF1_RS09140	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BTF1_RS09150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTF1_RS09180	COG0583	DNA-binding transcription factor activity
BTF1_RS09185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTF1_RS09195	COG0583	DNA-binding transcription factor activity
BTF1_RS09200	COG2258	MOSC domain
BTF1_RS09215	COG1132	(ABC) transporter
BTF1_RS09220	COG1132	(ABC) transporter
BTF1_RS09245	COG1396	sequence-specific DNA binding
BTF1_RS09275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTF1_RS09280	COG1595	DNA-templated transcription, initiation
BTF1_RS09305	COG1649	PFAM Uncharacterised BCR, COG1649
BTF1_RS09330	COG2971	BadF BadG BcrA BcrD
BTF1_RS09340	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BTF1_RS09350	COG1846	Transcriptional regulator
BTF1_RS09365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF1_RS09380	COG0500	methyltransferase
BTF1_RS09380	COG3615	Tellurite resistance protein tehB
BTF1_RS09390	COG2226	methyltransferase
BTF1_RS09395	COG3961	Belongs to the TPP enzyme family
BTF1_RS09430	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTF1_RS09455	COG2002	toxin-antitoxin pair type II binding
BTF1_RS09465	COG0730	response to heat
BTF1_RS09475	COG1686	Belongs to the peptidase S11 family
BTF1_RS09490	COG2814	Major facilitator Superfamily
BTF1_RS09520	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS09565	COG0741	lytic transglycosylase activity
BTF1_RS09570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTF1_RS09580	COG0456	acetyltransferase
BTF1_RS09590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BTF1_RS09595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTF1_RS09600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BTF1_RS09615	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BTF1_RS09625	COG2234	aminopeptidase activity
BTF1_RS09630	COG2814	Major facilitator Superfamily
BTF1_RS09670	COG1396	sequence-specific DNA binding
BTF1_RS09715	COG0768	penicillin binding
BTF1_RS09720	COG1595	DNA-templated transcription, initiation
BTF1_RS09730	COG0768	penicillin binding
BTF1_RS09740	COG2801	Transposase and inactivated derivatives
BTF1_RS09745	COG0768	penicillin binding
BTF1_RS09755	COG1408	metallophosphoesterase
BTF1_RS09765	COG3842	ATPase activity
BTF1_RS09770	COG1131	(ABC) transporter
BTF1_RS09780	COG1309	transcriptional regulator
BTF1_RS09795	COG1960	acyl-CoA dehydrogenase activity
BTF1_RS09800	COG0439	Biotin carboxylase
BTF1_RS09805	COG0511	ligase activity, forming carbon-carbon bonds
BTF1_RS09810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTF1_RS09815	COG1024	Enoyl-CoA hydratase
BTF1_RS09820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BTF1_RS09825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTF1_RS09850	COG1686	Belongs to the peptidase S11 family
BTF1_RS09880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTF1_RS09895	COG3227	Zinc metalloprotease (Elastase)
BTF1_RS09900	COG2207	Transcriptional regulator
BTF1_RS09930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BTF1_RS09940	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS09945	COG1733	regulation of RNA biosynthetic process
BTF1_RS09990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTF1_RS10005	COG1063	alcohol dehydrogenase
BTF1_RS10015	COG2323	membrane
BTF1_RS10025	COG0693	protein deglycase activity
BTF1_RS10035	COG3386	PFAM SMP-30 Gluconolaconase
BTF1_RS10040	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BTF1_RS10045	COG3773	Cell wall hydrolase
BTF1_RS10055	COG0745	RESPONSE REGULATOR receiver
BTF1_RS10060	COG2205	protein histidine kinase activity
BTF1_RS10065	COG0583	DNA-binding transcription factor activity
BTF1_RS10070	COG0667	Aldo Keto reductase
BTF1_RS10075	COG0488	(ABC) transporter
BTF1_RS10090	COG1136	(ABC) transporter
BTF1_RS10095	COG0577	efflux transmembrane transporter activity
BTF1_RS10120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTF1_RS10130	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BTF1_RS10185	COG2124	cytochrome p450
BTF1_RS10220	COG0561	phosphatase activity
BTF1_RS10225	COG5002	protein histidine kinase activity
BTF1_RS10230	COG0768	penicillin binding
BTF1_RS10240	COG1819	glycosyl
BTF1_RS10245	COG1794	racemase activity, acting on amino acids and derivatives
BTF1_RS10295	COG0662	Cupin 2, conserved barrel domain protein
BTF1_RS10310	COG1329	Transcriptional regulator
BTF1_RS10365	COG1733	regulation of RNA biosynthetic process
BTF1_RS10375	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BTF1_RS10385	COG2918	glutathione biosynthetic process
BTF1_RS10385	COG1181	Belongs to the D-alanine--D-alanine ligase family
BTF1_RS10395	COG0640	Transcriptional regulator
BTF1_RS10405	COG0288	reversible hydration of carbon dioxide
BTF1_RS10415	COG2814	Major facilitator Superfamily
BTF1_RS10425	COG0415	Belongs to the DNA photolyase family
BTF1_RS10435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTF1_RS10445	COG2155	Conserved Protein
BTF1_RS10455	COG2801	Transposase and inactivated derivatives
BTF1_RS10465	COG1090	epimerase
BTF1_RS10490	COG1533	DNA photolyase activity
BTF1_RS10525	COG2205	protein histidine kinase activity
BTF1_RS10580	COG2169	Transcriptional regulator
BTF1_RS10605	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTF1_RS10610	COG0604	alcohol dehydrogenase
BTF1_RS10615	COG0671	phosphoesterase, PA-phosphatase related
BTF1_RS10620	COG0768	penicillin binding
BTF1_RS10665	COG2814	Major facilitator Superfamily
BTF1_RS10680	COG0584	glycerophosphoryl diester phosphodiesterase
BTF1_RS10700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTF1_RS10705	COG0697	spore germination
BTF1_RS10730	COG0494	nUDIX hydrolase
BTF1_RS10740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTF1_RS10750	COG2223	nitrite transmembrane transporter activity
BTF1_RS10765	COG0592	DNA-directed DNA polymerase activity
BTF1_RS10770	COG1051	belongs to the nudix hydrolase family
BTF1_RS10795	COG3878	Protein conserved in bacteria
BTF1_RS10815	COG4667	esterase of the alpha-beta hydrolase superfamily
BTF1_RS10855	COG0322	excinuclease ABC activity
BTF1_RS10890	COG1819	glycosyl
BTF1_RS10895	COG1819	glycosyl
BTF1_RS10910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTF1_RS10935	COG1011	Hydrolase
BTF1_RS10940	COG0745	RESPONSE REGULATOR receiver
BTF1_RS10945	COG5002	protein histidine kinase activity
BTF1_RS10960	COG1136	(ABC) transporter
BTF1_RS10965	COG0577	efflux transmembrane transporter activity
BTF1_RS10970	COG1073	alpha beta
BTF1_RS10975	COG0657	acetylesterase activity
BTF1_RS10980	COG0076	glutamate decarboxylase activity
BTF1_RS10995	COG1523	belongs to the glycosyl hydrolase 13 family
BTF1_RS11000	COG3227	Zinc metalloprotease (Elastase)
BTF1_RS11005	COG0737	Belongs to the 5'-nucleotidase family
BTF1_RS11020	COG0346	lactoylglutathione lyase activity
BTF1_RS11025	COG0201	protein transport
BTF1_RS11030	COG0697	spore germination
BTF1_RS11035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTF1_RS11075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTF1_RS11090	COG2959	enzyme of heme biosynthesis
BTF1_RS11130	COG1309	transcriptional regulator
BTF1_RS11150	COG3284	Transcriptional regulator
BTF1_RS11170	COG1349	DNA-binding transcription factor activity
BTF1_RS11185	COG1959	2 iron, 2 sulfur cluster binding
BTF1_RS11200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTF1_RS11205	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTF1_RS11210	COG0022	dehydrogenase e1 component
BTF1_RS11215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTF1_RS11225	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS11230	COG0456	acetyltransferase
BTF1_RS11230	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTF1_RS11265	COG4176	ABC-type proline glycine betaine transport system permease component
BTF1_RS11270	COG0517	IMP dehydrogenase activity
BTF1_RS11270	COG4175	Glycine betaine
BTF1_RS11300	COG2153	protein acetylation
BTF1_RS11320	COG3397	chitin binding
BTF1_RS11325	COG1819	glycosyl
BTF1_RS11335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BTF1_RS11345	COG2205	protein histidine kinase activity
BTF1_RS11350	COG2267	carboxylic ester hydrolase activity
BTF1_RS11350	COG2226	methyltransferase
BTF1_RS11355	COG2315	Protein conserved in bacteria
BTF1_RS11405	COG0456	acetyltransferase
BTF1_RS11410	COG3973	AAA domain
BTF1_RS11425	COG0514	ATP-dependent DNA helicase (RecQ)
BTF1_RS11455	COG4637	Psort location Cytoplasmic, score
BTF1_RS11480	COG3397	chitin binding
BTF1_RS11495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTF1_RS11500	COG1115	amino acid carrier protein
BTF1_RS11505	COG1012	belongs to the aldehyde dehydrogenase family
BTF1_RS11510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTF1_RS11520	COG3938	Belongs to the proline racemase family
BTF1_RS11525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTF1_RS11570	COG0586	Pfam SNARE associated Golgi protein
BTF1_RS11580	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BTF1_RS11585	COG4166	transmembrane transport
BTF1_RS11595	COG4948	Mandelate Racemase Muconate Lactonizing
BTF1_RS11610	COG0667	Aldo Keto reductase
BTF1_RS11655	COG5002	protein histidine kinase activity
BTF1_RS11655	COG3850	Histidine kinase
BTF1_RS11660	COG0745	RESPONSE REGULATOR receiver
BTF1_RS11685	COG1164	Oligoendopeptidase f
BTF1_RS11690	COG1307	EDD domain protein, DegV family
BTF1_RS11730	COG2814	Major facilitator Superfamily
BTF1_RS11740	COG1664	Polymer-forming cytoskeletal
BTF1_RS11745	COG0789	Transcriptional regulator
BTF1_RS11750	COG4533	DNA binding
BTF1_RS11755	COG2814	Major facilitator Superfamily
BTF1_RS11755	COG0477	Major facilitator Superfamily
BTF1_RS11775	COG2261	transglycosylase associated protein
BTF1_RS11790	COG2226	methyltransferase
BTF1_RS11825	COG0436	Aminotransferase
BTF1_RS11830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTF1_RS11875	COG0628	permease
BTF1_RS11890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTF1_RS11895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTF1_RS11925	COG2746	aminoglycoside 3-N-acetyltransferase activity
BTF1_RS11935	COG0697	spore germination
BTF1_RS11940	COG2318	DinB family
BTF1_RS11960	COG4912	Dna alkylation repair
BTF1_RS11965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTF1_RS11970	COG0346	lactoylglutathione lyase activity
BTF1_RS11975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF1_RS12005	COG0861	Integral membrane protein TerC family
BTF1_RS12010	COG1368	sulfuric ester hydrolase activity
BTF1_RS12015	COG0488	(ABC) transporter
BTF1_RS12020	COG2409	Drug exporters of the RND superfamily
BTF1_RS12020	COG1033	growth of symbiont in host cell
BTF1_RS12025	COG1309	transcriptional regulator
BTF1_RS12040	COG0287	Prephenate dehydrogenase
BTF1_RS12055	COG1605	Chorismate mutase
BTF1_RS12055	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTF1_RS12090	COG1388	LysM domain
BTF1_RS12090	COG3584	3D domain protein
BTF1_RS12120	COG1879	ABC-type sugar transport system periplasmic component
BTF1_RS12130	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTF1_RS12140	COG2390	Transcriptional regulator
BTF1_RS12145	COG1070	Carbohydrate kinase
BTF1_RS12170	COG2329	Antibiotic biosynthesis monooxygenase
BTF1_RS12185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTF1_RS12200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTF1_RS12205	COG4187	Peptidase family M20/M25/M40
BTF1_RS12210	COG1414	Transcriptional regulator
BTF1_RS12215	COG0833	amino acid
BTF1_RS12225	COG1690	Belongs to the RtcB family
BTF1_RS12235	COG3239	Fatty acid desaturase
BTF1_RS12245	COG2720	vancomycin resistance protein
BTF1_RS12250	COG1785	Belongs to the alkaline phosphatase family
BTF1_RS12260	COG3655	Transcriptional regulator
BTF1_RS12280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTF1_RS12285	COG0346	lactoylglutathione lyase activity
BTF1_RS12305	COG0714	Associated with various cellular activities
BTF1_RS12330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTF1_RS12335	COG0753	catalase activity
BTF1_RS12365	COG5444	nuclease activity
BTF1_RS12390	COG0778	Nitroreductase
BTF1_RS12395	COG1846	Transcriptional regulator
BTF1_RS12415	COG3831	ATPase activity
BTF1_RS12415	COG4884	unkown
BTF1_RS12425	COG1136	(ABC) transporter
BTF1_RS12445	COG2207	Transcriptional regulator
BTF1_RS12450	COG0456	acetyltransferase
BTF1_RS12460	COG2816	NAD+ diphosphatase activity
BTF1_RS12465	COG0697	spore germination
BTF1_RS12470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTF1_RS12515	COG0730	response to heat
BTF1_RS12525	COG0833	amino acid
BTF1_RS12570	COG1329	Transcriptional regulator
BTF1_RS12585	COG5002	protein histidine kinase activity
BTF1_RS12610	COG0768	penicillin binding
BTF1_RS12640	COG1984	allophanate hydrolase subunit 2
BTF1_RS12645	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BTF1_RS12650	COG1414	Transcriptional regulator
BTF1_RS12665	COG0640	Transcriptional regulator
BTF1_RS12675	COG1960	acyl-CoA dehydrogenase activity
BTF1_RS12690	COG3314	Sporulation integral membrane protein YlbJ
BTF1_RS12730	COG3848	Pyruvate phosphate dikinase
BTF1_RS12730	COG0574	Belongs to the PEP-utilizing enzyme family
BTF1_RS12735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF1_RS12755	COG1063	alcohol dehydrogenase
BTF1_RS12765	COG1027	Aspartate ammonia-lyase
BTF1_RS12775	COG1396	sequence-specific DNA binding
BTF1_RS12795	COG5002	protein histidine kinase activity
BTF1_RS12820	COG2207	Transcriptional regulator
BTF1_RS12825	COG0322	excinuclease ABC activity
BTF1_RS12830	COG0531	amino acid
BTF1_RS12835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTF1_RS12845	COG0531	amino acid
BTF1_RS12850	COG0697	spore germination
BTF1_RS12855	COG0784	Response regulator, receiver
BTF1_RS12860	COG4191	Histidine kinase
BTF1_RS12870	COG1115	amino acid carrier protein
BTF1_RS12880	COG2124	cytochrome p450
BTF1_RS12895	COG0737	Belongs to the 5'-nucleotidase family
BTF1_RS12910	COG1335	isochorismatase
BTF1_RS12930	COG0583	DNA-binding transcription factor activity
BTF1_RS12935	COG1846	Transcriptional regulator
BTF1_RS12940	COG0598	Magnesium transport protein CorA
BTF1_RS12960	COG1073	alpha beta
BTF1_RS12980	COG0415	Belongs to the DNA photolyase family
BTF1_RS12985	COG0288	reversible hydration of carbon dioxide
BTF1_RS12995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTF1_RS13000	COG5609	conserved protein (DUF2294)
BTF1_RS13015	COG1575	Belongs to the MenA family. Type 1 subfamily
BTF1_RS13020	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTF1_RS13025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTF1_RS13030	COG1121	(ABC) transporter
BTF1_RS13050	COG0798	PFAM Bile acid sodium symporter
BTF1_RS13055	COG0346	lactoylglutathione lyase activity
BTF1_RS13060	COG0640	Transcriptional regulator
BTF1_RS13070	COG0583	DNA-binding transcription factor activity
BTF1_RS13110	COG1476	TRANSCRIPTIONal
BTF1_RS13120	COG0825	malonyl-CoA metabolic process
BTF1_RS13130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTF1_RS13130	COG3320	Male sterility
BTF1_RS13135	COG1309	transcriptional regulator
BTF1_RS13140	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS13145	COG1522	sequence-specific DNA binding
BTF1_RS13160	COG0346	lactoylglutathione lyase activity
BTF1_RS13185	COG0745	RESPONSE REGULATOR receiver
BTF1_RS13230	COG0277	FAD linked oxidase domain protein
BTF1_RS13240	COG1136	(ABC) transporter
BTF1_RS13275	COG2814	Major facilitator Superfamily
BTF1_RS13285	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BTF1_RS13305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BTF1_RS13325	COG0577	efflux transmembrane transporter activity
BTF1_RS13345	COG5002	protein histidine kinase activity
BTF1_RS13345	COG3850	Histidine kinase
BTF1_RS13355	COG2364	Membrane
BTF1_RS13360	COG1846	Transcriptional regulator
BTF1_RS13365	COG0456	acetyltransferase
BTF1_RS13370	COG2808	Putative FMN-binding domain
BTF1_RS13375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTF1_RS13400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTF1_RS13420	COG0662	Cupin 2, conserved barrel domain protein
BTF1_RS13425	COG2207	Transcriptional regulator
BTF1_RS13425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTF1_RS13440	COG3409	Peptidoglycan-binding domain 1 protein
BTF1_RS13440	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTF1_RS13455	COG2814	Major facilitator Superfamily
BTF1_RS13510	COG4282	regulation of fungal-type cell wall biogenesis
BTF1_RS13565	COG5444	nuclease activity
BTF1_RS13590	COG1876	peptidase activity
BTF1_RS13595	COG2843	Capsule synthesis protein
BTF1_RS13605	COG0477	Major facilitator Superfamily
BTF1_RS13620	COG1846	Transcriptional regulator
BTF1_RS13625	COG2814	Major facilitator Superfamily
BTF1_RS13635	COG2031	fatty acid transporter
BTF1_RS13645	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTF1_RS13695	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BTF1_RS13700	COG1288	antiporter activity
BTF1_RS13705	COG2356	endonuclease I
BTF1_RS13715	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTF1_RS13720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BTF1_RS13740	COG1733	regulation of RNA biosynthetic process
BTF1_RS13745	COG0778	Nitroreductase
BTF1_RS13775	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS13785	COG1131	(ABC) transporter
BTF1_RS13810	COG1011	Hydrolase
BTF1_RS13815	COG2365	Tyrosine phosphatase family
BTF1_RS13830	COG1051	belongs to the nudix hydrolase family
BTF1_RS13840	COG0346	lactoylglutathione lyase activity
BTF1_RS13845	COG1940	carbohydrate kinase activity
BTF1_RS13850	COG0738	Major facilitator superfamily
BTF1_RS13855	COG0110	maltose O-acetyltransferase activity
BTF1_RS13865	COG1136	(ABC) transporter
BTF1_RS13880	COG0628	permease
BTF1_RS13910	COG0500	methyltransferase
BTF1_RS13920	COG0477	Major facilitator Superfamily
BTF1_RS13950	COG1253	flavin adenine dinucleotide binding
BTF1_RS13955	COG0789	Transcriptional regulator
BTF1_RS13960	COG0697	spore germination
BTF1_RS13975	COG1357	PFAM Pentapeptide repeats (8 copies)
BTF1_RS13980	COG3813	Protein conserved in bacteria
BTF1_RS13985	COG2706	6-phosphogluconolactonase activity
BTF1_RS13990	COG1070	Carbohydrate kinase
BTF1_RS13995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BTF1_RS14000	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BTF1_RS14005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BTF1_RS14010	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTF1_RS14025	COG0814	amino acid
BTF1_RS14055	COG1733	regulation of RNA biosynthetic process
BTF1_RS14060	COG2188	Transcriptional regulator
BTF1_RS14065	COG0673	inositol 2-dehydrogenase activity
BTF1_RS14085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF1_RS14110	COG0384	phenazine biosynthesis protein PhzF
BTF1_RS14120	COG0318	PFAM AMP-dependent synthetase and ligase
BTF1_RS14125	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTF1_RS14130	COG1733	regulation of RNA biosynthetic process
BTF1_RS14135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTF1_RS14160	COG1191	sigma factor activity
BTF1_RS14205	COG1151	hydroxylamine reductase activity
BTF1_RS14210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF1_RS14240	COG2072	flavoprotein involved in K transport
BTF1_RS14270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF1_RS14275	COG0604	alcohol dehydrogenase
BTF1_RS14280	COG1113	amino acid transport
BTF1_RS14285	COG2814	Major facilitator Superfamily
BTF1_RS14315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BTF1_RS14320	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTF1_RS14330	COG1247	-acetyltransferase
BTF1_RS14335	COG3739	integral membrane protein
BTF1_RS14365	COG0583	DNA-binding transcription factor activity
BTF1_RS14385	COG1193	negative regulation of DNA recombination
BTF1_RS14400	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BTF1_RS14405	COG1164	Oligoendopeptidase f
BTF1_RS14435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTF1_RS14460	COG0584	glycerophosphoryl diester phosphodiesterase
BTF1_RS14475	COG0640	Transcriptional regulator
BTF1_RS14480	COG0604	alcohol dehydrogenase
BTF1_RS14490	COG0457	Tetratricopeptide repeat
BTF1_RS14500	COG0385	Bile acid
BTF1_RS14505	COG0277	FAD linked oxidase domain protein
BTF1_RS14525	COG1252	NADH dehydrogenase
BTF1_RS14540	COG4641	Protein conserved in bacteria
BTF1_RS14550	COG2089	acid synthase
BTF1_RS14565	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BTF1_RS14570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BTF1_RS14575	COG1088	dTDP-glucose 4,6-dehydratase activity
BTF1_RS14585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BTF1_RS14590	COG0463	Glycosyl transferase, family 2
BTF1_RS14595	COG0463	Glycosyl transferase, family 2
BTF1_RS14605	COG0823	Involved in the tonB-independent uptake of proteins
BTF1_RS14610	COG3397	chitin binding
BTF1_RS14620	COG0697	spore germination
BTF1_RS14640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTF1_RS14660	COG0457	Tetratricopeptide repeat
BTF1_RS14720	COG1309	transcriptional regulator
BTF1_RS14785	COG4824	toxin secretion phage lysis holin
BTF1_RS14845	COG0740	serine-type endopeptidase activity
BTF1_RS14855	COG4626	Terminase
BTF1_RS14855	COG1802	Transcriptional regulator
BTF1_RS14900	COG0582	viral genome integration into host DNA
BTF1_RS15010	COG1396	sequence-specific DNA binding
BTF1_RS15045	COG1876	peptidase activity
BTF1_RS15070	COG3852	Histidine kinase
BTF1_RS15080	COG1285	pathogenesis
BTF1_RS15090	COG2514	catechol 2,3-dioxygenase activity
BTF1_RS15095	COG2720	vancomycin resistance protein
BTF1_RS15130	COG0716	FMN binding
BTF1_RS15140	COG1051	belongs to the nudix hydrolase family
BTF1_RS15160	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS15170	COG0165	Argininosuccinate lyase
BTF1_RS15185	COG4145	pantothenate transmembrane transporter activity
BTF1_RS15195	COG1012	belongs to the aldehyde dehydrogenase family
BTF1_RS15200	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS15210	COG1657	PFAM Prenyltransferase squalene oxidase
BTF1_RS15215	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BTF1_RS15220	COG2962	Rard protein
BTF1_RS15225	COG3326	Membrane
BTF1_RS15240	COG0489	protein tyrosine kinase activity
BTF1_RS15250	COG0314	molybdopterin synthase activity
BTF1_RS15255	COG0303	'Molybdopterin
BTF1_RS15260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTF1_RS15265	COG2116	formate transmembrane transporter activity
BTF1_RS15275	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTF1_RS15280	COG5609	conserved protein (DUF2294)
BTF1_RS15285	COG2427	Protein of unknown function (DUF1641)
BTF1_RS15290	COG3383	formate dehydrogenase (NAD+) activity
BTF1_RS15330	COG1388	LysM domain
BTF1_RS15330	COG3409	Peptidoglycan-binding domain 1 protein
BTF1_RS15330	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTF1_RS15430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTF1_RS15455	COG3617	BRO family, N-terminal domain
BTF1_RS15500	COG1484	DNA-dependent DNA replication
BTF1_RS15510	COG3723	Recombinational DNA repair protein, rece pathway
BTF1_RS15515	COG5377	YqaJ viral recombinase family
BTF1_RS15565	COG3383	formate dehydrogenase (NAD+) activity
BTF1_RS15615	COG2226	methyltransferase
BTF1_RS15620	COG4166	transmembrane transport
BTF1_RS15630	COG4166	transmembrane transport
BTF1_RS15635	COG1301	dicarboxylic acid transport
BTF1_RS15640	COG1316	TRANSCRIPTIONal
BTF1_RS15650	COG1595	DNA-templated transcription, initiation
BTF1_RS15660	COG1131	(ABC) transporter
BTF1_RS15680	COG0673	inositol 2-dehydrogenase activity
BTF1_RS15685	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTF1_RS15690	COG0187	DNA topoisomerase II activity
BTF1_RS15695	COG1832	CoA-binding protein
BTF1_RS15700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTF1_RS15705	COG0745	RESPONSE REGULATOR receiver
BTF1_RS15725	COG4841	protein insertion into membrane
BTF1_RS15730	COG0824	Thioesterase
BTF1_RS15755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTF1_RS15765	COG1122	ATPase activity
BTF1_RS15770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTF1_RS15800	COG2211	Major facilitator Superfamily
BTF1_RS15810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTF1_RS15825	COG0183	Belongs to the thiolase family
BTF1_RS15830	COG0318	PFAM AMP-dependent synthetase and ligase
BTF1_RS15835	COG1268	BioY protein
BTF1_RS15840	COG0318	PFAM AMP-dependent synthetase and ligase
BTF1_RS15845	COG1396	sequence-specific DNA binding
BTF1_RS15880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTF1_RS15890	COG5002	protein histidine kinase activity
BTF1_RS15895	COG0400	carboxylic ester hydrolase activity
BTF1_RS15900	COG0346	lactoylglutathione lyase activity
BTF1_RS15905	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTF1_RS15915	COG0069	glutamate synthase activity
BTF1_RS15920	COG1902	pentaerythritol trinitrate reductase activity
BTF1_RS15925	COG1329	Transcriptional regulator
BTF1_RS15930	COG0010	Belongs to the arginase family
BTF1_RS15980	COG4846	Membrane protein involved in cytochrome C biogenesis
BTF1_RS15985	COG0785	Cytochrome C biogenesis protein
BTF1_RS15995	COG1473	amidohydrolase
BTF1_RS16005	COG1131	(ABC) transporter
BTF1_RS16025	COG0583	DNA-binding transcription factor activity
BTF1_RS16035	COG1346	cytolysis
BTF1_RS16050	COG0730	response to heat
BTF1_RS16075	COG1132	(ABC) transporter
BTF1_RS16080	COG1132	(ABC) transporter
BTF1_RS16115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTF1_RS16120	COG0737	Belongs to the 5'-nucleotidase family
BTF1_RS16130	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTF1_RS16150	COG1695	Transcriptional regulator
BTF1_RS16160	COG0741	lytic transglycosylase activity
BTF1_RS16190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BTF1_RS16195	COG0174	glutamine synthetase
BTF1_RS16200	COG0789	Transcriptional regulator
BTF1_RS16205	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BTF1_RS16210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTF1_RS16215	COG2860	membrane
BTF1_RS16225	COG0464	growth
BTF1_RS16255	COG1388	LysM domain
BTF1_RS16255	COG3584	3D domain protein
BTF1_RS16260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTF1_RS16260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTF1_RS16260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTF1_RS16265	COG1105	Belongs to the carbohydrate kinase PfkB family
BTF1_RS16270	COG1349	DNA-binding transcription factor activity
BTF1_RS16275	COG1979	alcohol dehydrogenase
BTF1_RS16280	COG2322	membrane
BTF1_RS16295	COG1113	amino acid transport
BTF1_RS16310	COG1408	metallophosphoesterase
BTF1_RS16315	COG2116	formate transmembrane transporter activity
BTF1_RS16330	COG2217	Heavy metal translocating P-type atpase
BTF1_RS16335	COG2608	mercury ion transmembrane transporter activity
BTF1_RS16340	COG1937	Protein conserved in bacteria
BTF1_RS16360	COG2819	hydrolase of the alpha beta superfamily
BTF1_RS16365	COG1120	ATPase activity
BTF1_RS16370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTF1_RS16375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTF1_RS16380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTF1_RS16385	COG0708	Exodeoxyribonuclease III
BTF1_RS16390	COG2169	Transcriptional regulator
BTF1_RS16395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTF1_RS16400	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BTF1_RS16410	COG2364	Membrane
BTF1_RS16425	COG2267	carboxylic ester hydrolase activity
BTF1_RS16430	COG3300	MHYT domain
BTF1_RS16430	COG5001	Diguanylate cyclase
BTF1_RS16465	COG1346	cytolysis
BTF1_RS16475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTF1_RS16490	COG0840	transmembrane signaling receptor activity
BTF1_RS16500	COG1404	Belongs to the peptidase S8 family
BTF1_RS16505	COG3773	Cell wall hydrolase
BTF1_RS16515	COG1368	sulfuric ester hydrolase activity
BTF1_RS16520	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTF1_RS16545	COG4550	Control of competence regulator ComK, YlbF/YmcA
BTF1_RS16555	COG1013	pyruvate-flavodoxin oxidoreductase activity
BTF1_RS16560	COG0674	pyruvate-flavodoxin oxidoreductase activity
BTF1_RS16560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BTF1_RS16570	COG2359	stage V sporulation protein S
BTF1_RS16575	COG1692	metallophosphoesterase
BTF1_RS16600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTF1_RS16605	COG1426	Protein conserved in bacteria
BTF1_RS16620	COG0300	oxidoreductase activity
BTF1_RS16625	COG0612	Peptidase, M16
BTF1_RS16630	COG0612	Peptidase, M16
BTF1_RS16635	COG1079	Belongs to the binding-protein-dependent transport system permease family
BTF1_RS16640	COG4603	Belongs to the binding-protein-dependent transport system permease family
BTF1_RS16645	COG3845	ABC transporter
BTF1_RS16650	COG1744	ABC transporter substrate-binding protein PnrA-like
BTF1_RS16655	COG2188	Transcriptional regulator
BTF1_RS16670	COG0740	serine-type endopeptidase activity
BTF1_RS16675	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTF1_RS16685	COG0527	aspartate kinase activity
BTF1_RS16690	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTF1_RS16815	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BTF1_RS16820	COG1278	Cold shock
BTF1_RS16825	COG0582	viral genome integration into host DNA
BTF1_RS16860	COG0305	Participates in initiation and elongation during chromosome replication
BTF1_RS16905	COG1396	sequence-specific DNA binding
BTF1_RS16925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTF1_RS16930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTF1_RS16935	COG1873	PFAM PRC-barrel domain
BTF1_RS16940	COG0612	Peptidase, M16
BTF1_RS16945	COG0726	polysaccharide deacetylase
BTF1_RS16960	COG0196	riboflavin kinase activity
BTF1_RS16970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BTF1_RS16975	COG1550	Protein conserved in bacteria
BTF1_RS16985	COG1358	cellular component organization or biogenesis
BTF1_RS16990	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BTF1_RS16995	COG0195	Participates in both transcription termination and antitermination
BTF1_RS17015	COG0750	zinc metalloprotease
BTF1_RS17025	COG4589	Belongs to the CDS family
BTF1_RS17070	COG4974	Belongs to the 'phage' integrase family
BTF1_RS17080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTF1_RS17085	COG0758	DNA mediated transformation
BTF1_RS17090	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BTF1_RS17130	COG1837	Belongs to the UPF0109 family
BTF1_RS17140	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTF1_RS17150	COG0552	protein localization to endoplasmic reticulum
BTF1_RS17155	COG1196	nuclear chromosome segregation
BTF1_RS17165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTF1_RS17170	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS17175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BTF1_RS17190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BTF1_RS17195	COG1461	Dihydroxyacetone kinase
BTF1_RS17200	COG1302	Protein conserved in bacteria
BTF1_RS17215	COG1564	THIamine pyrophosphokinase
BTF1_RS17220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BTF1_RS17230	COG2815	serine threonine protein kinase
BTF1_RS17230	COG0515	serine threonine protein kinase
BTF1_RS17235	COG0631	protein serine/threonine phosphatase activity
BTF1_RS17245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTF1_RS17245	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTF1_RS17260	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BTF1_RS17265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTF1_RS17285	COG1561	YicC-like family, N-terminal region
BTF1_RS17290	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BTF1_RS17300	COG0006	proline dipeptidase activity
BTF1_RS17320	COG3069	C4-dicarboxylate transmembrane transporter activity
BTF1_RS17380	COG0564	pseudouridine synthase activity
BTF1_RS17400	COG3599	regulation of cell shape
BTF1_RS17405	COG2302	S4 RNA-binding domain
BTF1_RS17410	COG0762	integral membrane protein
BTF1_RS17420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BTF1_RS17430	COG1873	PFAM PRC-barrel domain
BTF1_RS17435	COG1191	sigma factor activity
BTF1_RS17440	COG1191	sigma factor activity
BTF1_RS17450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BTF1_RS17455	COG0849	cell division
BTF1_RS17475	COG0772	Belongs to the SEDS family
BTF1_RS17495	COG0768	penicillin binding
BTF1_RS17500	COG0768	penicillin binding
BTF1_RS17520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTF1_RS17535	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BTF1_RS17540	COG1399	metal-binding, possibly nucleic acid-binding protein
BTF1_RS17550	COG3480	Lon protease (S16) C-terminal proteolytic domain
BTF1_RS17555	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTF1_RS17560	COG3314	Sporulation integral membrane protein YlbJ
BTF1_RS17570	COG0742	ribosomal rna small subunit methyltransferase
BTF1_RS17585	COG3679	Belongs to the UPF0342 family
BTF1_RS17590	COG0406	alpha-ribazole phosphatase activity
BTF1_RS17605	COG2340	Cysteine-rich secretory protein family
BTF1_RS17620	COG3336	cytochrome c oxidase
BTF1_RS17655	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BTF1_RS17660	COG0772	Belongs to the SEDS family
BTF1_RS17670	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BTF1_RS17675	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BTF1_RS17685	COG4896	Protein conserved in bacteria
BTF1_RS17700	COG1217	gtp-binding protein TYPA
BTF1_RS17710	COG0483	inositol monophosphate 1-phosphatase activity
BTF1_RS17730	COG1982	Orn Lys Arg decarboxylase major
BTF1_RS17780	COG0022	dehydrogenase e1 component
BTF1_RS17785	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTF1_RS17800	COG0561	phosphatase activity
BTF1_RS17810	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTF1_RS17815	COG0569	domain protein
BTF1_RS17835	COG0583	DNA-binding transcription factor activity
BTF1_RS17840	COG0517	IMP dehydrogenase activity
BTF1_RS17850	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BTF1_RS17860	COG4703	Protein of unknown function (DUF1797)
BTF1_RS17875	COG2200	EAL domain
BTF1_RS17880	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS17885	COG1408	metallophosphoesterase
BTF1_RS17930	COG2814	Major facilitator Superfamily
BTF1_RS17950	COG3209	COG3209 Rhs family protein
BTF1_RS17960	COG2205	protein histidine kinase activity
BTF1_RS17970	COG0436	Aminotransferase
BTF1_RS17975	COG1609	Transcriptional regulator
BTF1_RS17980	COG3833	ABC-type maltose transport systems, permease component
BTF1_RS17985	COG1175	transmembrane transport
BTF1_RS17990	COG2182	Extracellular solute-binding protein
BTF1_RS18000	COG0366	Alpha amylase catalytic
BTF1_RS18005	COG3842	ATPase activity
BTF1_RS18045	COG0183	Belongs to the thiolase family
BTF1_RS18080	COG1695	Transcriptional regulator
BTF1_RS18085	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS18105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTF1_RS18110	COG0436	Aminotransferase
BTF1_RS18145	COG2084	Dehydrogenase
BTF1_RS18155	COG2199	diguanylate cyclase activity
BTF1_RS18160	COG0778	Nitroreductase
BTF1_RS18185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTF1_RS18185	COG2190	(PTS) system
BTF1_RS18185	COG1263	PTS System
BTF1_RS18190	COG3711	transcriptional antiterminator
BTF1_RS18200	COG2188	Transcriptional regulator
BTF1_RS18210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BTF1_RS18230	COG1547	Domain of unknown function (DUF309)
BTF1_RS18235	COG0456	acetyltransferase
BTF1_RS18240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTF1_RS18245	COG4086	secreted protein
BTF1_RS18250	COG0561	phosphatase activity
BTF1_RS18255	COG0697	spore germination
BTF1_RS18270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTF1_RS18295	COG0733	neurotransmitter:sodium symporter activity
BTF1_RS18315	COG1686	Belongs to the peptidase S11 family
BTF1_RS18320	COG1725	Transcriptional regulator
BTF1_RS18325	COG1131	(ABC) transporter
BTF1_RS18345	COG1846	Transcriptional regulator
BTF1_RS18360	COG0598	Magnesium transport protein CorA
BTF1_RS18385	COG4974	Belongs to the 'phage' integrase family
BTF1_RS18395	COG0735	belongs to the Fur family
BTF1_RS18400	COG1300	Membrane
BTF1_RS18420	COG0667	Aldo Keto reductase
BTF1_RS18425	COG0656	L-ascorbic acid biosynthetic process
BTF1_RS18430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTF1_RS18430	COG0456	acetyltransferase
BTF1_RS18440	COG4085	toxin activity
BTF1_RS18440	COG1525	nuclease
BTF1_RS18440	COG0737	Belongs to the 5'-nucleotidase family
BTF1_RS18450	COG0596	Alpha beta hydrolase
BTF1_RS18455	COG2056	Na+-H+ antiporter family
BTF1_RS18460	COG1609	Transcriptional regulator
BTF1_RS18465	COG0456	acetyltransferase
BTF1_RS18470	COG1073	alpha beta
BTF1_RS18485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTF1_RS18485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTF1_RS18490	COG0307	riboflavin synthase, alpha
BTF1_RS18520	COG1073	alpha beta
BTF1_RS18520	COG2226	methyltransferase
BTF1_RS18535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTF1_RS18550	COG1757	Na H antiporter
BTF1_RS18555	COG0737	Belongs to the 5'-nucleotidase family
BTF1_RS18565	COG1522	sequence-specific DNA binding
BTF1_RS18610	COG0300	oxidoreductase activity
BTF1_RS18615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF1_RS18620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTF1_RS18625	COG1760	l-serine dehydratase
BTF1_RS18630	COG1760	l-serine dehydratase
BTF1_RS18660	COG1285	pathogenesis
BTF1_RS18670	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTF1_RS18675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTF1_RS18685	COG1376	ErfK ybiS ycfS ynhG family protein
BTF1_RS18690	COG4129	membrane
BTF1_RS18695	COG1126	abc transporter atp-binding protein
BTF1_RS18700	COG0765	amino acid transport
BTF1_RS18705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTF1_RS18725	COG2323	membrane
BTF1_RS18730	COG0772	Belongs to the SEDS family
BTF1_RS18735	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTF1_RS18740	COG0022	dehydrogenase e1 component
BTF1_RS18745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTF1_RS18750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTF1_RS18765	COG0280	phosphate acetyltransferase
BTF1_RS18770	COG3829	transcription factor binding
BTF1_RS18770	COG3290	protein histidine kinase activity
BTF1_RS18780	COG0584	glycerophosphoryl diester phosphodiesterase
BTF1_RS18785	COG3093	addiction module antidote protein HigA
BTF1_RS18815	COG2801	Transposase and inactivated derivatives
BTF1_RS18830	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTF1_RS18875	COG0750	zinc metalloprotease
BTF1_RS18880	COG0497	DNA recombination
BTF1_RS18890	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BTF1_RS18900	COG0142	geranyltranstransferase activity
BTF1_RS18925	COG1302	Protein conserved in bacteria
BTF1_RS18930	COG0439	Biotin carboxylase
BTF1_RS18935	COG0511	ligase activity, forming carbon-carbon bonds
BTF1_RS18975	COG3854	ATPases associated with a variety of cellular activities
BTF1_RS19000	COG0006	proline dipeptidase activity
BTF1_RS19015	COG3872	metal-dependent enzyme
BTF1_RS19025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTF1_RS19060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTF1_RS19070	COG1609	Transcriptional regulator
BTF1_RS19080	COG2076	Multidrug Resistance protein
BTF1_RS19085	COG2076	Multidrug Resistance protein
BTF1_RS19125	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTF1_RS19155	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BTF1_RS19190	COG1459	type II secretion system
BTF1_RS19195	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BTF1_RS19250	COG0646	methionine synthase
BTF1_RS19250	COG1410	methionine synthase
BTF1_RS19255	COG0646	methionine synthase
BTF1_RS19255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BTF1_RS19260	COG0626	cystathionine gamma-synthase activity
BTF1_RS19265	COG0626	cystathionine gamma-synthase activity
BTF1_RS19285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF1_RS19295	COG1940	carbohydrate kinase activity
BTF1_RS19300	COG4483	Protein conserved in bacteria
BTF1_RS19305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTF1_RS19310	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BTF1_RS19315	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTF1_RS19320	COG0704	Plays a role in the regulation of phosphate uptake
BTF1_RS19330	COG0573	inorganic phosphate transmembrane transporter activity
BTF1_RS19335	COG0573	inorganic phosphate transmembrane transporter activity
BTF1_RS19345	COG0768	penicillin binding
BTF1_RS19385	COG1388	LysM domain
BTF1_RS19385	COG3409	Peptidoglycan-binding domain 1 protein
BTF1_RS19385	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTF1_RS19480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTF1_RS19555	COG1396	sequence-specific DNA binding
BTF1_RS19570	COG0582	viral genome integration into host DNA
BTF1_RS19575	COG0477	Major facilitator Superfamily
BTF1_RS19580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTF1_RS19590	COG5521	maltodextrose utilization protein MalA
BTF1_RS19605	COG0735	belongs to the Fur family
BTF1_RS19610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTF1_RS19615	COG1121	(ABC) transporter
BTF1_RS19620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTF1_RS19650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BTF1_RS19655	COG2384	SAM-dependent methyltransferase
BTF1_RS19665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTF1_RS19670	COG0358	DNA primase activity
BTF1_RS19680	COG0517	IMP dehydrogenase activity
BTF1_RS19695	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BTF1_RS19700	COG0295	cytidine deaminase activity
BTF1_RS19705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BTF1_RS19715	COG1480	7TM receptor with intracellular HD hydrolase
BTF1_RS19720	COG1702	phosphate starvation-inducible protein PhoH
BTF1_RS19735	COG1610	YqeY-like protein
BTF1_RS19740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BTF1_RS19745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTF1_RS19750	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BTF1_RS19780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTF1_RS19785	COG1733	regulation of RNA biosynthetic process
BTF1_RS19810	COG1466	dna polymerase III delta subunit
BTF1_RS19820	COG2333	competence protein COMEC
BTF1_RS19820	COG0658	competence protein
BTF1_RS19825	COG2131	deaminase
BTF1_RS19830	COG1596	polysaccharide export
BTF1_RS19830	COG1555	photosystem II stabilization
BTF1_RS19835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTF1_RS19840	COG2226	methyltransferase
BTF1_RS19845	COG0799	negative regulation of ribosome biogenesis
BTF1_RS19850	COG1713	HD superfamily hydrolase involved in NAD metabolism
BTF1_RS19860	COG1534	Rna-binding protein
BTF1_RS19870	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BTF1_RS19875	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BTF1_RS19900	COG1595	DNA-templated transcription, initiation
BTF1_RS19910	COG0778	Nitroreductase
BTF1_RS19915	COG2357	RelA SpoT domain protein
BTF1_RS19925	COG1785	Belongs to the alkaline phosphatase family
BTF1_RS19935	COG2267	carboxylic ester hydrolase activity
BTF1_RS19970	COG1404	Belongs to the peptidase S8 family
BTF1_RS19975	COG3186	Phenylalanine-4-hydroxylase
BTF1_RS19985	COG2514	catechol 2,3-dioxygenase activity
BTF1_RS19990	COG2259	Doxx family
BTF1_RS20030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTF1_RS20040	COG1012	belongs to the aldehyde dehydrogenase family
BTF1_RS20040	COG1454	alcohol dehydrogenase
BTF1_RS20045	COG0626	cystathionine gamma-synthase activity
BTF1_RS20050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTF1_RS20075	COG0768	penicillin binding
BTF1_RS20095	COG0826	peptidase U32
BTF1_RS20100	COG0826	peptidase U32
BTF1_RS20105	COG4122	O-methyltransferase activity
BTF1_RS20110	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BTF1_RS20125	COG4472	Bacterial protein of unknown function (DUF965)
BTF1_RS20140	COG0628	permease
BTF1_RS20160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BTF1_RS20175	COG1104	cysteine desulfurase activity
BTF1_RS20180	COG1959	2 iron, 2 sulfur cluster binding
BTF1_RS20185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BTF1_RS20195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BTF1_RS20225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTF1_RS20235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BTF1_RS20235	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BTF1_RS20240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTF1_RS20245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTF1_RS20245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTF1_RS20255	COG2244	polysaccharide biosynthetic process
BTF1_RS20260	COG2323	membrane
BTF1_RS20270	COG1862	Preprotein translocase
BTF1_RS20300	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BTF1_RS20330	COG0157	Belongs to the NadC ModD family
BTF1_RS20335	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BTF1_RS20340	COG1104	cysteine desulfurase activity
BTF1_RS20345	COG1827	regulation of RNA biosynthetic process
BTF1_RS20350	COG2258	MOSC domain
BTF1_RS20360	COG0077	Prephenate dehydratase
BTF1_RS20365	COG0577	efflux transmembrane transporter activity
BTF1_RS20370	COG0577	efflux transmembrane transporter activity
BTF1_RS20375	COG1136	(ABC) transporter
BTF1_RS20380	COG5002	protein histidine kinase activity
BTF1_RS20385	COG0745	RESPONSE REGULATOR receiver
BTF1_RS20395	COG3290	protein histidine kinase activity
BTF1_RS20405	COG2868	ribosomal protein
BTF1_RS20415	COG1530	ribonuclease E activity
BTF1_RS20420	COG1994	Peptidase M50
BTF1_RS20425	COG0739	heme binding
BTF1_RS20430	COG2894	cell division
BTF1_RS20450	COG1077	Cell shape determining protein MreB Mrl
BTF1_RS20470	COG0285	dihydrofolate synthase activity
BTF1_RS20485	COG1388	LysM domain
BTF1_RS20495	COG0113	porphobilinogen synthase activity
BTF1_RS20500	COG1587	Uroporphyrinogen-III synthase
BTF1_RS20510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTF1_RS20520	COG1846	Transcriptional regulator
BTF1_RS20525	COG1764	response to oxidative stress
BTF1_RS20540	COG1067	ATP-dependent peptidase activity
BTF1_RS20540	COG0470	DNA polymerase III
BTF1_RS20570	COG2801	Transposase and inactivated derivatives
BTF1_RS20590	COG0622	Phosphoesterase
BTF1_RS20605	COG5401	PFAM Sporulation and spore germination
BTF1_RS20625	COG1309	transcriptional regulator
BTF1_RS20635	COG2197	response regulator
BTF1_RS20640	COG2233	PERMEase
BTF1_RS20645	COG0402	S-adenosylhomocysteine deaminase activity
BTF1_RS20650	COG1983	PspC domain protein
BTF1_RS20655	COG1396	sequence-specific DNA binding
BTF1_RS20660	COG0697	spore germination
BTF1_RS20670	COG1959	2 iron, 2 sulfur cluster binding
BTF1_RS20675	COG1668	transmembrane transport
BTF1_RS20680	COG4152	abc transporter atp-binding protein
BTF1_RS20685	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BTF1_RS20690	COG1360	Flagellar Motor Protein
BTF1_RS20695	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BTF1_RS20700	COG1876	peptidase activity
BTF1_RS20705	COG0824	Thioesterase
BTF1_RS20710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BTF1_RS20715	COG1053	succinate dehydrogenase
BTF1_RS20720	COG2009	succinate dehydrogenase
BTF1_RS20725	COG1719	4-vinyl reductase, 4VR
BTF1_RS20735	COG3118	belongs to the thioredoxin family
BTF1_RS20740	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BTF1_RS20745	COG2086	electron transfer activity
BTF1_RS20750	COG1024	Enoyl-CoA hydratase
BTF1_RS20755	COG1309	transcriptional regulator
BTF1_RS20760	COG0318	PFAM AMP-dependent synthetase and ligase
BTF1_RS20785	COG2318	DinB family
BTF1_RS20800	COG1131	(ABC) transporter
BTF1_RS20805	COG2205	protein histidine kinase activity
BTF1_RS20810	COG0745	RESPONSE REGULATOR receiver
BTF1_RS20820	COG4895	conserved protein (DUF2196)
BTF1_RS20825	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BTF1_RS20835	COG4509	Sortase family
BTF1_RS20840	COG1120	ATPase activity
BTF1_RS20855	COG5386	Cell surface protein
BTF1_RS20865	COG5386	Cell surface protein
BTF1_RS20870	COG1114	Component of the transport system for branched-chain amino acids
BTF1_RS20875	COG1187	pseudouridine synthase activity
BTF1_RS20885	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTF1_RS20885	COG1796	DNA polymerase
BTF1_RS20890	COG1286	toxin biosynthetic process
BTF1_RS20930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTF1_RS20940	COG1418	mRNA catabolic process
BTF1_RS20955	COG2814	Major facilitator Superfamily
BTF1_RS20960	COG1566	PFAM secretion protein HlyD family protein
BTF1_RS20965	COG1309	transcriptional regulator
BTF1_RS20970	COG1363	Peptidase, m42
BTF1_RS20995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTF1_RS21010	COG1484	DNA-dependent DNA replication
BTF1_RS21015	COG3611	Membrane attachment protein
BTF1_RS21025	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BTF1_RS21030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTF1_RS21035	COG0237	dephospho-CoA kinase activity
BTF1_RS21040	COG1971	Probably functions as a manganese efflux pump
BTF1_RS21050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTF1_RS21050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTF1_RS21055	COG5002	protein histidine kinase activity
BTF1_RS21060	COG0745	RESPONSE REGULATOR receiver
BTF1_RS21080	COG0538	isocitrate dehydrogenase activity
BTF1_RS21085	COG0372	Belongs to the citrate synthase family
BTF1_RS21095	COG0628	permease
BTF1_RS21100	COG3030	protein affecting phage T7 exclusion by the F plasmid
BTF1_RS21125	COG1725	Transcriptional regulator
BTF1_RS21130	COG0281	malic enzyme
BTF1_RS21135	COG0587	DNA-directed DNA polymerase activity
BTF1_RS21150	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BTF1_RS21165	COG4109	DRTGG domain
BTF1_RS21180	COG0006	proline dipeptidase activity
BTF1_RS21210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTF1_RS21215	COG0662	Cupin 2, conserved barrel domain protein
BTF1_RS21230	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS21235	COG0589	response to stress
BTF1_RS21275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTF1_RS21300	COG0827	DNA restriction-modification system
BTF1_RS21305	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BTF1_RS21310	COG3874	Sporulation protein YtfJ
BTF1_RS21325	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BTF1_RS21335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTF1_RS21350	COG1104	cysteine desulfurase activity
BTF1_RS21360	COG0583	DNA-binding transcription factor activity
BTF1_RS21365	COG0697	spore germination
BTF1_RS21370	COG1309	transcriptional regulator
BTF1_RS21375	COG1956	GAF domain-containing protein
BTF1_RS21380	COG0626	cystathionine gamma-synthase activity
BTF1_RS21405	COG0110	maltose O-acetyltransferase activity
BTF1_RS21410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTF1_RS21415	COG0454	-acetyltransferase
BTF1_RS21420	COG0517	IMP dehydrogenase activity
BTF1_RS21425	COG0123	including yeast histone deacetylase and acetoin utilization protein
BTF1_RS21440	COG0745	RESPONSE REGULATOR receiver
BTF1_RS21445	COG5002	protein histidine kinase activity
BTF1_RS21450	COG0666	response to abiotic stimulus
BTF1_RS21485	COG1609	Transcriptional regulator
BTF1_RS21490	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTF1_RS21490	COG1605	Chorismate mutase
BTF1_RS21495	COG1605	Chorismate mutase
BTF1_RS21495	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTF1_RS21500	COG1605	Chorismate mutase
BTF1_RS21500	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTF1_RS21505	COG4851	CamS sex pheromone cAM373 precursor
BTF1_RS21510	COG3118	belongs to the thioredoxin family
BTF1_RS21520	COG2309	aminopeptidase activity
BTF1_RS21535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTF1_RS21540	COG0697	spore germination
BTF1_RS21545	COG0789	Transcriptional regulator
BTF1_RS21560	COG1674	ftsk spoiiie
BTF1_RS21575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTF1_RS21585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTF1_RS21590	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BTF1_RS21595	COG1363	Peptidase, m42
BTF1_RS21605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF1_RS21620	COG0510	thiamine kinase activity
BTF1_RS21625	COG1523	belongs to the glycosyl hydrolase 13 family
BTF1_RS21635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTF1_RS21640	COG1349	DNA-binding transcription factor activity
BTF1_RS21645	COG1187	pseudouridine synthase activity
BTF1_RS21650	COG2244	polysaccharide biosynthetic process
BTF1_RS21655	COG2081	HI0933 family
BTF1_RS21660	COG2814	Major facilitator Superfamily
BTF1_RS21670	COG3832	glyoxalase III activity
BTF1_RS21690	COG1329	Transcriptional regulator
BTF1_RS21715	COG0314	molybdopterin synthase activity
BTF1_RS21720	COG1763	Mo-molybdopterin cofactor biosynthetic process
BTF1_RS21725	COG0303	'Molybdopterin
BTF1_RS21735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTF1_RS21740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTF1_RS21760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTF1_RS21770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTF1_RS21810	COG2814	Major facilitator Superfamily
BTF1_RS21815	COG0475	glutathione-regulated potassium exporter activity
BTF1_RS21820	COG0490	domain, Protein
BTF1_RS21825	COG0582	viral genome integration into host DNA
BTF1_RS21835	COG1136	(ABC) transporter
BTF1_RS21855	COG1242	4 iron, 4 sulfur cluster binding
BTF1_RS21860	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BTF1_RS21865	COG1794	racemase activity, acting on amino acids and derivatives
BTF1_RS21880	COG2267	carboxylic ester hydrolase activity
BTF1_RS21885	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTF1_RS21890	COG0671	phosphoesterase, PA-phosphatase related
BTF1_RS21895	COG0438	transferase activity, transferring glycosyl groups
BTF1_RS21985	COG5002	protein histidine kinase activity
BTF1_RS21990	COG3852	Histidine kinase
BTF1_RS21995	COG0753	catalase activity
BTF1_RS22000	COG2267	carboxylic ester hydrolase activity
BTF1_RS22005	COG1368	sulfuric ester hydrolase activity
BTF1_RS22015	COG4895	conserved protein (DUF2196)
BTF1_RS22030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTF1_RS22035	COG1116	anion transmembrane transporter activity
BTF1_RS22040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTF1_RS22065	COG0494	nUDIX hydrolase
BTF1_RS22095	COG2076	Multidrug Resistance protein
BTF1_RS22100	COG2076	Multidrug Resistance protein
BTF1_RS22105	COG0789	Transcriptional regulator
BTF1_RS22110	COG1854	S-ribosylhomocysteine lyase activity
BTF1_RS22120	COG0288	reversible hydration of carbon dioxide
BTF1_RS22125	COG1271	oxidase subunit
BTF1_RS22130	COG1294	oxidase, subunit
BTF1_RS22150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTF1_RS22175	COG1842	Phage shock protein A
BTF1_RS22200	COG3859	Proton-coupled thiamine transporter YuaJ
BTF1_RS22205	COG5002	protein histidine kinase activity
BTF1_RS22210	COG0745	RESPONSE REGULATOR receiver
BTF1_RS22235	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTF1_RS22240	COG1597	lipid kinase activity
BTF1_RS22290	COG5002	protein histidine kinase activity
BTF1_RS22300	COG0586	Pfam SNARE associated Golgi protein
BTF1_RS22310	COG0577	efflux transmembrane transporter activity
BTF1_RS22315	COG1136	(ABC) transporter
BTF1_RS22320	COG2207	Transcriptional regulator
BTF1_RS22320	COG3708	Transcriptional regulator
BTF1_RS22330	COG1131	(ABC) transporter
BTF1_RS22335	COG5658	integral membrane protein
BTF1_RS22340	COG0640	Transcriptional regulator
BTF1_RS22350	COG0745	RESPONSE REGULATOR receiver
BTF1_RS22355	COG2205	protein histidine kinase activity
BTF1_RS22360	COG0577	efflux transmembrane transporter activity
BTF1_RS22365	COG0577	efflux transmembrane transporter activity
BTF1_RS22370	COG1136	(ABC) transporter
BTF1_RS22375	COG0577	efflux transmembrane transporter activity
BTF1_RS22390	COG2188	Transcriptional regulator
BTF1_RS22410	COG3964	amidohydrolase
BTF1_RS22430	COG4948	Mandelate Racemase Muconate Lactonizing
BTF1_RS22440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BTF1_RS22445	COG0596	Alpha beta hydrolase
BTF1_RS22455	COG1169	isochorismate synthase
BTF1_RS22460	COG1575	Belongs to the MenA family. Type 1 subfamily
BTF1_RS22465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BTF1_RS22470	COG1278	Cold shock
BTF1_RS22495	COG0058	SHG alpha-glucan phosphorylase activity
BTF1_RS22505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BTF1_RS22510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BTF1_RS22530	COG1309	transcriptional regulator
BTF1_RS22665	COG1285	pathogenesis
BTF1_RS22670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTF1_RS22685	COG2155	Conserved Protein
BTF1_RS22690	COG1098	S1 RNA binding domain
BTF1_RS22695	COG0436	Aminotransferase
BTF1_RS22700	COG1522	sequence-specific DNA binding
BTF1_RS22705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTF1_RS22710	COG2267	carboxylic ester hydrolase activity
BTF1_RS22720	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BTF1_RS22740	COG5018	Exonuclease
BTF1_RS22745	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTF1_RS22765	COG2050	protein possibly involved in aromatic compounds catabolism
BTF1_RS22775	COG1268	BioY protein
BTF1_RS22780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTF1_RS22785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTF1_RS22800	COG3584	3D domain protein
BTF1_RS22815	COG1252	NADH dehydrogenase
BTF1_RS22825	COG3708	Transcriptional regulator
BTF1_RS22840	COG1683	Conserved Protein
BTF1_RS22865	COG0316	Belongs to the HesB IscA family
BTF1_RS22880	COG1252	NADH dehydrogenase
BTF1_RS22890	COG2274	protein secretion by the type I secretion system
BTF1_RS22895	COG0390	transport system, permease component
BTF1_RS22900	COG2824	Alkylphosphonate utilization operon protein PhnA
BTF1_RS22945	COG4837	Protein of unknown function (DUF1462)
BTF1_RS22950	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BTF1_RS22960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTF1_RS22965	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BTF1_RS22985	COG1358	cellular component organization or biogenesis
BTF1_RS22995	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTF1_RS23000	COG0647	UMP catabolic process
BTF1_RS23010	COG2445	Protein of unknown function DUF86
BTF1_RS23015	COG1494	fructose-1,6-bisphosphatase
BTF1_RS23030	COG4470	Protein conserved in bacteria
BTF1_RS23040	COG0789	Transcriptional regulator
BTF1_RS23045	COG4377	Putative membrane peptidase family (DUF2324)
BTF1_RS23070	COG0739	heme binding
BTF1_RS23080	COG3377	Domain of unknown function (DUF1805)
BTF1_RS23085	COG0737	Belongs to the 5'-nucleotidase family
BTF1_RS23090	COG0719	Fe-S assembly protein
BTF1_RS23095	COG0822	iron-sulfur transferase activity
BTF1_RS23100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BTF1_RS23105	COG0719	Fe-S assembly protein
BTF1_RS23110	COG0396	ATPase activity
BTF1_RS23115	COG1464	Belongs to the NlpA lipoprotein family
BTF1_RS23120	COG1464	Belongs to the NlpA lipoprotein family
BTF1_RS23125	COG2011	ABC-type metal ion transport system permease component
BTF1_RS23140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTF1_RS23145	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BTF1_RS23155	COG1393	Belongs to the ArsC family
BTF1_RS23175	COG0039	L-malate dehydrogenase activity
BTF1_RS23190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTF1_RS23195	COG1960	acyl-CoA dehydrogenase activity
BTF1_RS23200	COG0183	Belongs to the thiolase family
BTF1_RS23205	COG1024	Enoyl-CoA hydratase
BTF1_RS23205	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTF1_RS23215	COG1686	Belongs to the peptidase S11 family
BTF1_RS23230	COG0011	TIGRFAM Protein of
BTF1_RS23235	COG0840	transmembrane signaling receptor activity
BTF1_RS23250	COG2814	Major facilitator Superfamily
BTF1_RS23255	COG0531	amino acid
BTF1_RS23280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTF1_RS23310	COG0586	Pfam SNARE associated Golgi protein
BTF1_RS23320	COG1376	ErfK ybiS ycfS ynhG family protein
BTF1_RS23325	COG0745	RESPONSE REGULATOR receiver
BTF1_RS23330	COG5002	protein histidine kinase activity
BTF1_RS23360	COG0840	transmembrane signaling receptor activity
BTF1_RS23365	COG2151	metal-sulfur cluster biosynthetic enzyme
BTF1_RS23375	COG2801	Transposase and inactivated derivatives
BTF1_RS23380	COG3227	Zinc metalloprotease (Elastase)
BTF1_RS23400	COG0586	Pfam SNARE associated Golgi protein
BTF1_RS23405	COG0475	glutathione-regulated potassium exporter activity
BTF1_RS23410	COG0490	domain, Protein
BTF1_RS23415	COG1115	amino acid carrier protein
BTF1_RS23420	COG0783	Belongs to the Dps family
BTF1_RS23435	COG1611	Belongs to the LOG family
BTF1_RS23445	COG1528	Iron-storage protein
BTF1_RS23455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTF1_RS23460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTF1_RS23465	COG1115	amino acid carrier protein
BTF1_RS23470	COG1115	amino acid carrier protein
BTF1_RS23475	COG2910	NAD(P)H-binding
BTF1_RS23490	COG0656	L-ascorbic acid biosynthetic process
BTF1_RS23495	COG2814	Major facilitator Superfamily
BTF1_RS23500	COG1733	regulation of RNA biosynthetic process
BTF1_RS23510	COG1252	NADH dehydrogenase
BTF1_RS23530	COG0840	transmembrane signaling receptor activity
BTF1_RS23530	COG3290	protein histidine kinase activity
BTF1_RS23565	COG0488	(ABC) transporter
BTF1_RS23570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTF1_RS23590	COG1335	isochorismatase
BTF1_RS23595	COG1522	sequence-specific DNA binding
BTF1_RS23605	COG1522	sequence-specific DNA binding
BTF1_RS23610	COG0288	reversible hydration of carbon dioxide
BTF1_RS23615	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BTF1_RS23620	COG2233	PERMEase
BTF1_RS23665	COG0557	exoribonuclease II activity
BTF1_RS23670	COG1647	Serine aminopeptidase, S33
BTF1_RS23675	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTF1_RS23680	COG1346	cytolysis
BTF1_RS23715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTF1_RS23730	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BTF1_RS23755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTF1_RS23770	COG2323	membrane
BTF1_RS23780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTF1_RS23790	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BTF1_RS23800	COG1051	belongs to the nudix hydrolase family
BTF1_RS23810	COG0492	ferredoxin-NADP+ reductase activity
BTF1_RS23815	COG0457	Tetratricopeptide repeat
BTF1_RS23820	COG0110	maltose O-acetyltransferase activity
BTF1_RS23840	COG1950	PFAM Membrane protein of
BTF1_RS23850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BTF1_RS23870	COG0789	Transcriptional regulator
BTF1_RS23890	COG0583	DNA-binding transcription factor activity
BTF1_RS23900	COG0655	NAD(P)H dehydrogenase (quinone) activity
BTF1_RS23905	COG0488	(ABC) transporter
BTF1_RS23915	COG1132	(ABC) transporter
BTF1_RS23920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTF1_RS23925	COG3409	Peptidoglycan-binding domain 1 protein
BTF1_RS23925	COG0793	Belongs to the peptidase S41A family
BTF1_RS23930	COG2177	Part of the ABC transporter FtsEX involved in
BTF1_RS23935	COG2884	Cell division ATP-binding protein ftsE
BTF1_RS23945	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BTF1_RS23955	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BTF1_RS23960	COG1278	Cold shock
BTF1_RS23965	COG1040	competence protein
BTF1_RS23970	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BTF1_RS23975	COG1388	LysM domain
BTF1_RS23975	COG0791	NLP P60 protein
BTF1_RS23980	COG1733	regulation of RNA biosynthetic process
BTF1_RS23985	COG1307	EDD domain protein, DegV family
BTF1_RS23990	COG1739	Uncharacterized protein family UPF0029
BTF1_RS23995	COG1316	TRANSCRIPTIONal
BTF1_RS24000	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BTF1_RS24005	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BTF1_RS24010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTF1_RS24020	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BTF1_RS24020	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BTF1_RS24040	COG1486	melibiose metabolic process
BTF1_RS24045	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTF1_RS24050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTF1_RS24060	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BTF1_RS24070	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTF1_RS24080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTF1_RS24085	COG1301	dicarboxylic acid transport
BTF1_RS24100	COG1511	domain protein
BTF1_RS24105	COG0583	DNA-binding transcription factor activity
BTF1_RS24120	COG1271	oxidase subunit
BTF1_RS24125	COG1294	oxidase, subunit
BTF1_RS24130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTF1_RS24140	COG1620	l-lactate permease
BTF1_RS24150	COG2389	metal-binding protein
BTF1_RS24160	COG1368	sulfuric ester hydrolase activity
BTF1_RS24170	COG1388	LysM domain
BTF1_RS24170	COG0791	NLP P60 protein
BTF1_RS24175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTF1_RS24185	COG1215	transferase activity, transferring glycosyl groups
BTF1_RS24195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTF1_RS24200	COG3584	3D domain protein
BTF1_RS24200	COG1388	LysM domain
BTF1_RS24225	COG4715	Zinc finger, swim domain protein
BTF1_RS24230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTF1_RS24270	COG0577	efflux transmembrane transporter activity
BTF1_RS24275	COG1136	(ABC) transporter
BTF1_RS24310	COG5002	protein histidine kinase activity
BTF1_RS24315	COG0745	RESPONSE REGULATOR receiver
BTF1_RS24325	COG1316	TRANSCRIPTIONal
BTF1_RS24330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTF1_RS24335	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BTF1_RS24340	COG1215	transferase activity, transferring glycosyl groups
BTF1_RS24345	COG0438	transferase activity, transferring glycosyl groups
BTF1_RS24365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTF1_RS24370	COG4464	protein tyrosine phosphatase activity
BTF1_RS24375	COG0489	protein tyrosine kinase activity
BTF1_RS24380	COG3944	biosynthesis protein
BTF1_RS24385	COG0489	protein tyrosine kinase activity
BTF1_RS24400	COG1609	Transcriptional regulator
BTF1_RS24410	COG0739	heme binding
BTF1_RS24425	COG3279	Response regulator of the LytR AlgR family
BTF1_RS24430	COG2385	sporulation resulting in formation of a cellular spore
BTF1_RS24445	COG4836	Membrane
BTF1_RS24450	COG1007	ATP synthesis coupled electron transport
BTF1_RS24455	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTF1_RS24460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTF1_RS24470	COG0839	Belongs to the complex I subunit 6 family
BTF1_RS24490	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTF1_RS24505	COG5001	Diguanylate cyclase
BTF1_RS24505	COG3300	MHYT domain
BTF1_RS24555	COG0356	it plays a direct role in the translocation of protons across the membrane
BTF1_RS24585	COG0698	ribose 5-phosphate isomerase
BTF1_RS24595	COG2190	(PTS) system
BTF1_RS24600	COG2259	Doxx family
BTF1_RS24605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTF1_RS24615	COG2801	Transposase and inactivated derivatives
BTF1_RS24635	COG0009	L-threonylcarbamoyladenylate synthase
BTF1_RS24670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BTF1_RS24675	COG1494	fructose-1,6-bisphosphatase
BTF1_RS24695	COG4821	SIS domain
BTF1_RS24715	COG1960	acyl-CoA dehydrogenase activity
BTF1_RS24720	COG1960	acyl-CoA dehydrogenase activity
BTF1_RS24725	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTF1_RS24730	COG0183	Belongs to the thiolase family
BTF1_RS24735	COG2181	nitrate reductase activity
BTF1_RS24735	COG0247	lactate metabolic process
BTF1_RS24740	COG3620	sequence-specific DNA binding
BTF1_RS24780	COG1404	Belongs to the peptidase S8 family
BTF1_RS24785	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BTF1_RS24830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTF1_RS24840	COG3300	MHYT domain
BTF1_RS24840	COG5001	Diguanylate cyclase
BTF1_RS24855	COG3227	Zinc metalloprotease (Elastase)
BTF1_RS24860	COG2197	response regulator
BTF1_RS24865	COG4585	Histidine kinase
BTF1_RS24870	COG0842	Transport permease protein
BTF1_RS24875	COG1131	(ABC) transporter
BTF1_RS24880	COG0024	Methionine aminopeptidase
BTF1_RS24890	COG2234	aminopeptidase activity
BTF1_RS24910	COG1595	DNA-templated transcription, initiation
BTF1_RS24920	COG4506	Protein conserved in bacteria
BTF1_RS24925	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTF1_RS24950	COG2814	Major facilitator Superfamily
BTF1_RS24955	COG0789	Transcriptional regulator
BTF1_RS24960	COG0584	glycerophosphoryl diester phosphodiesterase
BTF1_RS24965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTF1_RS24975	COG1994	Peptidase M50
BTF1_RS24985	COG1078	dGTPase activity
BTF1_RS24990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTF1_RS24995	COG1120	ATPase activity
BTF1_RS25000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTF1_RS25005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTF1_RS25025	COG0280	phosphate acetyltransferase
BTF1_RS25040	COG3773	Cell wall hydrolase
BTF1_RS25050	COG2363	Small membrane protein
BTF1_RS25060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTF1_RS25065	COG2233	PERMEase
BTF1_RS25070	COG0561	phosphatase activity
BTF1_RS25075	COG2814	Major facilitator Superfamily
BTF1_RS25085	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BTF1_RS25090	COG1131	(ABC) transporter
BTF1_RS25095	COG2755	lipolytic protein G-D-S-L family
BTF1_RS25100	COG1609	Transcriptional regulator
BTF1_RS25110	COG0460	homoserine dehydrogenase
BTF1_RS25120	COG2873	o-acetylhomoserine
BTF1_RS25125	COG1011	Hydrolase
BTF1_RS25130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTF1_RS25140	COG2197	response regulator
BTF1_RS25145	COG4585	Histidine kinase
BTF1_RS25145	COG2203	Gaf domain
BTF1_RS25150	COG0351	phosphomethylpyrimidine kinase
BTF1_RS25155	COG3706	GGDEF domain
BTF1_RS25160	COG2879	small protein
BTF1_RS25165	COG1966	Carbon starvation protein
BTF1_RS25170	COG3279	Response regulator of the LytR AlgR family
BTF1_RS25175	COG0477	Major facilitator Superfamily
BTF1_RS25185	COG0438	transferase activity, transferring glycosyl groups
BTF1_RS25200	COG0840	transmembrane signaling receptor activity
BTF1_RS25210	COG1607	acyl-coa hydrolase
BTF1_RS25215	COG1216	Glycosyl transferase, family 2
BTF1_RS25230	COG1216	Glycosyl transferase, family 2
BTF1_RS25240	COG4485	Bacterial membrane protein, YfhO
BTF1_RS25245	COG0463	Glycosyl transferase, family 2
BTF1_RS25255	COG1309	transcriptional regulator
BTF1_RS25260	COG0488	(ABC) transporter
BTF1_RS25265	COG1309	transcriptional regulator
BTF1_RS25270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTF1_RS25275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTF1_RS25275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTF1_RS25280	COG0628	permease
BTF1_RS25300	COG3275	phosphorelay sensor kinase activity
BTF1_RS25305	COG2814	Major facilitator Superfamily
BTF1_RS25310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTF1_RS25315	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BTF1_RS25340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTF1_RS25345	COG1272	protein, Hemolysin III
BTF1_RS25365	COG1164	Oligoendopeptidase f
BTF1_RS25380	COG2801	Transposase and inactivated derivatives
BTF1_RS25390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTF1_RS25435	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTF1_RS25440	COG0322	excinuclease ABC activity
BTF1_RS25485	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BTF1_RS25500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTF1_RS25505	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BTF1_RS25510	COG4853	Protein conserved in bacteria
BTF1_RS25520	COG5002	protein histidine kinase activity
BTF1_RS25525	COG0745	RESPONSE REGULATOR receiver
BTF1_RS25555	COG0305	Participates in initiation and elongation during chromosome replication
BTF1_RS25565	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BTF1_RS25570	COG4241	membrane
BTF1_RS25580	COG0629	single-stranded DNA binding
BTF1_RS25590	COG0012	GTP binding
BTF1_RS25595	COG4481	Protein conserved in bacteria
BTF1_RS25600	COG0668	transmembrane transport
BTF1_RS25610	COG1475	DNA binding
BTF1_RS25615	COG1192	Involved in chromosome partitioning
BTF1_RS25640	COG1847	R3H domain protein
BTF1_RS25655	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BTF1_RS25665	COG0592	DNA-directed DNA polymerase activity
BTF1_RS25670	COG2501	S4 domain
BTF1_RS25680	COG0187	DNA topoisomerase II activity
BTF1_RS25685	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTF1_RS25710	COG0516	GMP reductase activity
BTF1_RS25710	COG0517	IMP dehydrogenase activity
BTF1_RS25715	COG1686	Belongs to the peptidase S11 family
BTF1_RS25745	COG1428	Deoxynucleoside kinase
BTF1_RS25750	COG1428	Deoxynucleoside kinase
BTF1_RS25755	COG1335	isochorismatase
BTF1_RS25760	COG0590	tRNA wobble adenosine to inosine editing
BTF1_RS25765	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTF1_RS25810	COG1982	Orn Lys Arg decarboxylase major
BTF1_RS25820	COG0470	DNA polymerase III
BTF1_RS25825	COG1774	PSP1 C-terminal conserved region
BTF1_RS25835	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BTF1_RS25845	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BTF1_RS25850	COG2002	toxin-antitoxin pair type II binding
BTF1_RS25860	COG0084	hydrolase, TatD family'
BTF1_RS25880	COG4466	Protein conserved in bacteria
BTF1_RS25895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BTF1_RS25900	COG0251	oxidation-reduction process
BTF1_RS25930	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTF1_RS25935	COG2002	toxin-antitoxin pair type II binding
BTF1_RS25940	COG2244	polysaccharide biosynthetic process
BTF1_RS25945	COG3956	TIGRFAM MazG family protein
BTF1_RS25950	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BTF1_RS25970	COG1098	S1 RNA binding domain
BTF1_RS25985	COG2208	phosphoserine phosphatase activity
BTF1_RS25995	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTF1_RS26000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTF1_RS26015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTF1_RS26020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BTF1_RS26025	COG0512	Glutamine amidotransferase of anthranilate synthase
BTF1_RS26030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTF1_RS26035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BTF1_RS26040	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BTF1_RS26045	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BTF1_RS26050	COG1396	sequence-specific DNA binding
BTF1_RS26055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTF1_RS26145	COG3880	PFAM UvrB UvrC protein
BTF1_RS26155	COG0542	response to heat
BTF1_RS26160	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BTF1_RS26170	COG4956	integral membrane protein (PIN domain superfamily)
BTF1_RS26190	COG1045	serine acetyltransferase
BTF1_RS26205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTF1_RS26210	COG3688	RNA-binding protein containing a PIN domain
BTF1_RS26220	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTF1_RS26225	COG0250	Participates in transcription elongation, termination and antitermination
BTF1_RS26230	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BTF1_RS26250	COG2813	Specifically methylates the guanine in position
BTF1_RS26260	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BTF1_RS26265	COG1358	cellular component organization or biogenesis
BTF1_RS26270	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BTF1_RS26290	COG0051	transcription antitermination factor activity, RNA binding
BTF1_RS26295	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BTF1_RS26335	COG0255	Belongs to the universal ribosomal protein uL29 family
BTF1_RS26395	COG0201	protein transport
BTF1_RS26405	COG0024	Methionine aminopeptidase
BTF1_RS26415	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BTF1_RS26450	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BTF1_RS26475	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTF1_RS26480	COG0489	protein tyrosine kinase activity
BTF1_RS26490	COG2194	sulfuric ester hydrolase activity
BTF1_RS26495	COG0726	polysaccharide deacetylase
BTF1_RS26575	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BTF1_RS26580	COG4856	YbbR-like protein
BTF1_RS26615	COG1028	Short-chain dehydrogenase reductase Sdr
BTF1_RS26620	COG2011	ABC-type metal ion transport system permease component
BTF1_RS26625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BTF1_RS26630	COG1464	Belongs to the NlpA lipoprotein family
BTF1_RS26635	COG0604	alcohol dehydrogenase
BTF1_RS26645	COG0277	FAD linked oxidase domain protein
BTF1_RS26650	COG2271	Major facilitator Superfamily
BTF1_RS26660	COG2814	Major facilitator Superfamily
BTF1_RS26680	COG0601	transmembrane transport
BTF1_RS26685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTF1_RS26690	COG0444	Belongs to the ABC transporter superfamily
BTF1_RS26695	COG4608	Belongs to the ABC transporter superfamily
BTF1_RS26700	COG4166	transmembrane transport
BTF1_RS26715	COG4166	transmembrane transport
BTF1_RS26720	COG4166	transmembrane transport
BTF1_RS26725	COG0656	L-ascorbic acid biosynthetic process
BTF1_RS26745	COG4149	molybdate abc transporter
BTF1_RS26750	COG0725	ABC transporter, periplasmic molybdate-binding protein
BTF1_RS26755	COG1910	domain protein
BTF1_RS26765	COG0697	spore germination
BTF1_RS26775	COG0204	Acyl-transferase
BTF1_RS26780	COG1609	Transcriptional regulator
BTF1_RS26790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTF1_RS26810	COG5298	Protein conserved in bacteria
BTF1_RS26830	COG0488	(ABC) transporter
BTF1_RS26840	COG0747	negative chemotaxis
BTF1_RS26845	COG0601	transmembrane transport
BTF1_RS26850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTF1_RS26855	COG0444	Belongs to the ABC transporter superfamily
BTF1_RS26860	COG4608	Belongs to the ABC transporter superfamily
BTF1_RS26865	COG0561	phosphatase activity
BTF1_RS26880	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BTF1_RS26885	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTF1_RS26895	COG0531	amino acid
BTF1_RS26900	COG2814	Major facilitator Superfamily
BTF1_RS26910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BTF1_RS26920	COG4294	response to UV
BTF1_RS26925	COG0705	Rhomboid family
BTF1_RS26935	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BTF1_RS26940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTF1_RS26945	COG0864	Transcriptional regulator
BTF1_RS26950	COG2337	Toxic component of a toxin-antitoxin (TA) module
BTF1_RS26955	COG2183	response to ionizing radiation
BTF1_RS27050	COG0802	atpase or kinase
BTF1_RS27055	COG1214	PFAM Peptidase M22, glycoprotease
BTF1_RS27060	COG0456	acetyltransferase
BTF1_RS27070	COG0488	(ABC) transporter
BTF1_RS27085	COG1266	CAAX protease self-immunity
BTF1_RS27100	COG0582	viral genome integration into host DNA
BTF1_RS27210	COG1674	ftsk spoiiie
BTF1_RS27220	COG2946	Replication initiation factor
BTF1_RS27235	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BTF1_RS27245	COG2252	PERMEase
BTF1_RS27255	COG5002	protein histidine kinase activity
BTF1_RS27280	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BTF1_RS27300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTF1_RS27345	COG2205	protein histidine kinase activity
BTF1_RS27350	COG0745	RESPONSE REGULATOR receiver
BTF1_RS27370	COG0697	spore germination
BTF1_RS27395	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTF1_RS27400	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BTF1_RS27405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTF1_RS27415	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTF1_RS27430	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BTF1_RS27440	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BTF1_RS27450	COG0151	Belongs to the GarS family
BTF1_RS27475	COG0210	DNA helicase
BTF1_RS27485	COG4851	CamS sex pheromone cAM373 precursor
BTF1_RS27500	COG1335	isochorismatase
BTF1_RS27510	COG2011	ABC-type metal ion transport system permease component
BTF1_RS27515	COG1464	Belongs to the NlpA lipoprotein family
BTF1_RS27525	COG0003	Pfam Anion-transporting ATPase
BTF1_RS27530	COG1846	Transcriptional regulator
BTF1_RS27535	COG4682	membrane
BTF1_RS27555	COG1597	lipid kinase activity
BTF1_RS27560	COG0546	phosphoglycolate phosphatase activity
BTF1_RS27565	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTF1_RS27575	COG1012	belongs to the aldehyde dehydrogenase family
BTF1_RS27580	COG2076	Multidrug Resistance protein
BTF1_RS27590	COG2309	aminopeptidase activity
BTF1_RS27605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTF1_RS27615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTF1_RS27620	COG4807	Protein conserved in bacteria
BTF1_RS27650	COG1757	Na H antiporter
BTF1_RS27655	COG1473	amidohydrolase
BTF1_RS27670	COG0450	alkyl hydroperoxide reductase
BTF1_RS27680	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BTF1_RS27690	COG2801	Transposase and inactivated derivatives
BTF1_RS27700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTF1_RS27705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTF1_RS27710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTF1_RS27725	COG0166	Belongs to the GPI family
BTF1_RS27750	COG5002	protein histidine kinase activity
BTF1_RS27770	COG3541	Predicted nucleotidyltransferase
BTF1_RS27775	COG2814	Major facilitator Superfamily
BTF1_RS27780	COG0723	plastoquinol--plastocyanin reductase activity
BTF1_RS27780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTF1_RS27790	COG0765	amino acid transport
BTF1_RS27795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTF1_RS27800	COG1126	abc transporter atp-binding protein
BTF1_RS27805	COG0840	transmembrane signaling receptor activity
BTF1_RS27830	COG0549	Belongs to the carbamate kinase family
BTF1_RS27835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTF1_RS27845	COG0277	FAD linked oxidase domain protein
BTF1_RS27850	COG0366	Alpha amylase catalytic
BTF1_RS27855	COG1263	PTS System
BTF1_RS27855	COG2190	(PTS) system
BTF1_RS27855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTF1_RS27885	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BTF1_RS27905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTF1_RS27910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTF1_RS27915	COG1116	anion transmembrane transporter activity
BTF1_RS27920	COG0488	(ABC) transporter
BTF1_RS27965	COG2270	Major facilitator Superfamily
BTF1_RS28395	COG4129	membrane
BTF1_RS28415	COG0069	glutamate synthase activity
BTF1_RS28415	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BTF1_RS29140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTF1_RS29180	COG1620	l-lactate permease
BTF1_RS29205	COG3104	oligopeptide transport
BTF1_RS29240	COG4548	von Willebrand factor, type A
BTF1_RS29250	COG4548	von Willebrand factor, type A
BTF1_RS29265	COG0714	Associated with various cellular activities
BTF1_RS29710	COG0569	domain protein
BTF1_RS29710	COG0475	glutathione-regulated potassium exporter activity
BTF1_RS30085	COG1316	TRANSCRIPTIONal
BTF1_RS30120	COG1283	sodium-dependent phosphate transmembrane transporter activity
BTF1_RS30465	COG2766	serine protein kinase
BTF1_RS30470	COG2766	serine protein kinase
BTF1_RS30595	COG3290	protein histidine kinase activity
BTF1_RS30705	COG3290	protein histidine kinase activity
BTF1_RS30810	COG3383	formate dehydrogenase (NAD+) activity
BTF1_RS30925	COG2217	Heavy metal translocating P-type atpase
BTF1_RS31005	COG1253	flavin adenine dinucleotide binding
BTF1_RS31020	COG1027	Aspartate ammonia-lyase
BTF1_RS31225	COG0366	Alpha amylase catalytic
BTF1_RS31700	COG1882	Formate acetyltransferase
BTF1_RS31910	COG2766	serine protein kinase
BTF1_RS32185	COG1253	flavin adenine dinucleotide binding
BTF1_RS32555	COG2217	Heavy metal translocating P-type atpase
BTF1_RS32635	COG2376	Dihydroxyacetone kinase