locus-tag	class	description
A3L20_RS00010	COG0592	DNA-directed DNA polymerase activity
A3L20_RS00015	COG2501	S4 domain
A3L20_RS00025	COG0187	DNA topoisomerase II activity
A3L20_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A3L20_RS00065	COG0517	IMP dehydrogenase activity
A3L20_RS00065	COG0516	GMP reductase activity
A3L20_RS00070	COG1686	Belongs to the peptidase S11 family
A3L20_RS00100	COG1428	Deoxynucleoside kinase
A3L20_RS00105	COG1428	Deoxynucleoside kinase
A3L20_RS00110	COG1335	isochorismatase
A3L20_RS00115	COG0590	tRNA wobble adenosine to inosine editing
A3L20_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A3L20_RS00180	COG1982	Orn Lys Arg decarboxylase major
A3L20_RS00190	COG0470	DNA polymerase III
A3L20_RS00195	COG1774	PSP1 C-terminal conserved region
A3L20_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A3L20_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A3L20_RS00220	COG2002	toxin-antitoxin pair type II binding
A3L20_RS00230	COG0084	hydrolase, TatD family'
A3L20_RS00250	COG4466	Protein conserved in bacteria
A3L20_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A3L20_RS00270	COG0251	oxidation-reduction process
A3L20_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A3L20_RS00305	COG2002	toxin-antitoxin pair type II binding
A3L20_RS00310	COG2244	polysaccharide biosynthetic process
A3L20_RS00315	COG3956	TIGRFAM MazG family protein
A3L20_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A3L20_RS00340	COG1098	S1 RNA binding domain
A3L20_RS00355	COG2208	phosphoserine phosphatase activity
A3L20_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A3L20_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L20_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3L20_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A3L20_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
A3L20_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A3L20_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A3L20_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A3L20_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A3L20_RS00420	COG1396	sequence-specific DNA binding
A3L20_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A3L20_RS00515	COG3880	PFAM UvrB UvrC protein
A3L20_RS00525	COG0542	response to heat
A3L20_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A3L20_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
A3L20_RS00560	COG1045	serine acetyltransferase
A3L20_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A3L20_RS00580	COG3688	RNA-binding protein containing a PIN domain
A3L20_RS00590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A3L20_RS00595	COG0250	Participates in transcription elongation, termination and antitermination
A3L20_RS00600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A3L20_RS00620	COG2813	Specifically methylates the guanine in position
A3L20_RS00630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L20_RS00635	COG1358	cellular component organization or biogenesis
A3L20_RS00640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A3L20_RS00660	COG0051	transcription antitermination factor activity, RNA binding
A3L20_RS00665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A3L20_RS00705	COG0255	Belongs to the universal ribosomal protein uL29 family
A3L20_RS00765	COG0201	protein transport
A3L20_RS00775	COG0024	Methionine aminopeptidase
A3L20_RS00785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A3L20_RS00820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A3L20_RS00845	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3L20_RS00850	COG0489	protein tyrosine kinase activity
A3L20_RS00860	COG2194	sulfuric ester hydrolase activity
A3L20_RS00865	COG0726	polysaccharide deacetylase
A3L20_RS00945	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A3L20_RS00950	COG4856	YbbR-like protein
A3L20_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS00990	COG2011	ABC-type metal ion transport system permease component
A3L20_RS00995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A3L20_RS01000	COG1464	Belongs to the NlpA lipoprotein family
A3L20_RS01005	COG0604	alcohol dehydrogenase
A3L20_RS01015	COG0277	FAD linked oxidase domain protein
A3L20_RS01020	COG2271	Major facilitator Superfamily
A3L20_RS01030	COG2814	Major facilitator Superfamily
A3L20_RS01050	COG0601	transmembrane transport
A3L20_RS01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L20_RS01060	COG0444	Belongs to the ABC transporter superfamily
A3L20_RS01065	COG4608	Belongs to the ABC transporter superfamily
A3L20_RS01070	COG4166	transmembrane transport
A3L20_RS01085	COG4166	transmembrane transport
A3L20_RS01090	COG4166	transmembrane transport
A3L20_RS01095	COG0656	L-ascorbic acid biosynthetic process
A3L20_RS01110	COG4149	molybdate abc transporter
A3L20_RS01115	COG0725	ABC transporter, periplasmic molybdate-binding protein
A3L20_RS01120	COG1910	domain protein
A3L20_RS01130	COG0697	spore germination
A3L20_RS01140	COG0204	Acyl-transferase
A3L20_RS01145	COG1609	Transcriptional regulator
A3L20_RS01155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3L20_RS01165	COG2963	transposase activity
A3L20_RS01170	COG2801	Transposase and inactivated derivatives
A3L20_RS01185	COG5298	Protein conserved in bacteria
A3L20_RS01205	COG0488	(ABC) transporter
A3L20_RS01215	COG0747	negative chemotaxis
A3L20_RS01220	COG0601	transmembrane transport
A3L20_RS01225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L20_RS01230	COG0444	Belongs to the ABC transporter superfamily
A3L20_RS01235	COG4608	Belongs to the ABC transporter superfamily
A3L20_RS01240	COG0561	phosphatase activity
A3L20_RS01265	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A3L20_RS01270	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3L20_RS01280	COG0531	amino acid
A3L20_RS01285	COG2814	Major facilitator Superfamily
A3L20_RS01295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A3L20_RS01305	COG4294	response to UV
A3L20_RS01310	COG0705	Rhomboid family
A3L20_RS01320	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A3L20_RS01325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A3L20_RS01330	COG0864	Transcriptional regulator
A3L20_RS01335	COG2337	Toxic component of a toxin-antitoxin (TA) module
A3L20_RS01340	COG2183	response to ionizing radiation
A3L20_RS01435	COG0802	atpase or kinase
A3L20_RS01440	COG1214	PFAM Peptidase M22, glycoprotease
A3L20_RS01445	COG0456	acetyltransferase
A3L20_RS01455	COG0488	(ABC) transporter
A3L20_RS01470	COG1266	CAAX protease self-immunity
A3L20_RS01490	COG2252	PERMEase
A3L20_RS01500	COG5002	protein histidine kinase activity
A3L20_RS01525	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A3L20_RS01545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L20_RS01570	COG0697	spore germination
A3L20_RS01595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A3L20_RS01600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A3L20_RS01605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3L20_RS01615	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A3L20_RS01630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A3L20_RS01640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A3L20_RS01650	COG0151	Belongs to the GarS family
A3L20_RS01675	COG0210	DNA helicase
A3L20_RS01685	COG4851	CamS sex pheromone cAM373 precursor
A3L20_RS01700	COG1335	isochorismatase
A3L20_RS01710	COG2011	ABC-type metal ion transport system permease component
A3L20_RS01715	COG1464	Belongs to the NlpA lipoprotein family
A3L20_RS01725	COG0003	Pfam Anion-transporting ATPase
A3L20_RS01730	COG1846	Transcriptional regulator
A3L20_RS01735	COG4682	membrane
A3L20_RS01755	COG1597	lipid kinase activity
A3L20_RS01760	COG0546	phosphoglycolate phosphatase activity
A3L20_RS01765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3L20_RS01775	COG1012	belongs to the aldehyde dehydrogenase family
A3L20_RS01780	COG2076	Multidrug Resistance protein
A3L20_RS01790	COG2309	aminopeptidase activity
A3L20_RS01805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A3L20_RS01815	COG0582	viral genome integration into host DNA
A3L20_RS01825	COG3620	sequence-specific DNA binding
A3L20_RS01855	COG1484	DNA-dependent DNA replication
A3L20_RS01865	COG2002	toxin-antitoxin pair type II binding
A3L20_RS01910	COG3344	reverse transcriptase
A3L20_RS01945	COG0582	viral genome integration into host DNA
A3L20_RS02075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A3L20_RS02080	COG4807	Protein conserved in bacteria
A3L20_RS02105	COG1757	Na H antiporter
A3L20_RS02110	COG1473	amidohydrolase
A3L20_RS02125	COG0450	alkyl hydroperoxide reductase
A3L20_RS02135	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L20_RS02145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L20_RS02150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L20_RS02155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L20_RS02170	COG0166	Belongs to the GPI family
A3L20_RS02195	COG5002	protein histidine kinase activity
A3L20_RS02215	COG3541	Predicted nucleotidyltransferase
A3L20_RS02220	COG2801	Transposase and inactivated derivatives
A3L20_RS02230	COG2814	Major facilitator Superfamily
A3L20_RS02235	COG0723	plastoquinol--plastocyanin reductase activity
A3L20_RS02235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3L20_RS02245	COG0765	amino acid transport
A3L20_RS02250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3L20_RS02260	COG0840	transmembrane signaling receptor activity
A3L20_RS02290	COG0549	Belongs to the carbamate kinase family
A3L20_RS02295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3L20_RS02305	COG0277	FAD linked oxidase domain protein
A3L20_RS02310	COG0366	Alpha amylase catalytic
A3L20_RS02315	COG2190	(PTS) system
A3L20_RS02315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3L20_RS02315	COG1263	PTS System
A3L20_RS02345	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A3L20_RS02370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A3L20_RS02375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A3L20_RS02380	COG1116	anion transmembrane transporter activity
A3L20_RS02425	COG2270	Major facilitator Superfamily
A3L20_RS02455	COG2310	stress, protein
A3L20_RS02460	COG2310	stress, protein
A3L20_RS02465	COG2310	stress, protein
A3L20_RS02470	COG0861	Integral membrane protein TerC family
A3L20_RS02480	COG3853	Toxic anion resistance protein (TelA)
A3L20_RS02495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A3L20_RS02505	COG1295	ribonuclease BN
A3L20_RS02510	COG2217	Heavy metal translocating P-type atpase
A3L20_RS02515	COG0697	spore germination
A3L20_RS02525	COG0681	Belongs to the peptidase S26 family
A3L20_RS02535	COG0586	Pfam SNARE associated Golgi protein
A3L20_RS02550	COG3871	stress protein (general stress protein 26)
A3L20_RS02555	COG0387	Pfam Sodium calcium exchanger
A3L20_RS02565	COG0535	radical SAM domain protein
A3L20_RS02590	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A3L20_RS02595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L20_RS02615	COG3829	transcription factor binding
A3L20_RS02625	COG0833	amino acid
A3L20_RS02630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L20_RS02655	COG1263	PTS System
A3L20_RS02655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3L20_RS02660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3L20_RS02675	COG1216	Glycosyl transferase, family 2
A3L20_RS02685	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A3L20_RS02685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3L20_RS02690	COG0463	Glycosyl transferase, family 2
A3L20_RS02700	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A3L20_RS02720	COG1228	amidohydrolase
A3L20_RS02725	COG1090	epimerase
A3L20_RS02755	COG1988	membrane-bound metal-dependent
A3L20_RS02760	COG1194	a g-specific adenine glycosylase
A3L20_RS02785	COG1132	(ABC) transporter
A3L20_RS02790	COG4129	membrane
A3L20_RS02795	COG0067	glutamate synthase
A3L20_RS02795	COG0069	glutamate synthase activity
A3L20_RS02795	COG0070	glutamate synthase
A3L20_RS02805	COG4555	ABC transporter
A3L20_RS02835	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3L20_RS02840	COG0735	belongs to the Fur family
A3L20_RS02960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A3L20_RS02985	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A3L20_RS02995	COG2766	serine protein kinase
A3L20_RS03010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A3L20_RS03020	COG1585	Membrane protein implicated in regulation of membrane protease activity
A3L20_RS03025	COG2268	Band 7 protein
A3L20_RS03035	COG3290	protein histidine kinase activity
A3L20_RS03040	COG4565	transcriptional regulatory protein
A3L20_RS03045	COG2851	Citrate transporter
A3L20_RS03070	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A3L20_RS03075	COG3842	ATPase activity
A3L20_RS03080	COG1175	transmembrane transport
A3L20_RS03085	COG0395	ABC-type sugar transport system, permease component
A3L20_RS03095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A3L20_RS03100	COG0745	RESPONSE REGULATOR receiver
A3L20_RS03105	COG5002	protein histidine kinase activity
A3L20_RS03115	COG4990	cell redox homeostasis
A3L20_RS03125	COG3290	protein histidine kinase activity
A3L20_RS03130	COG4565	transcriptional regulatory protein
A3L20_RS03135	COG3493	citrate carrier protein
A3L20_RS03140	COG0281	malic enzyme
A3L20_RS03155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L20_RS03165	COG5002	protein histidine kinase activity
A3L20_RS03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A3L20_RS03195	COG3383	formate dehydrogenase (NAD+) activity
A3L20_RS03200	COG2427	Protein of unknown function (DUF1641)
A3L20_RS03215	COG0531	amino acid
A3L20_RS03220	COG0640	Transcriptional regulator
A3L20_RS03225	COG2217	Heavy metal translocating P-type atpase
A3L20_RS03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A3L20_RS03240	COG3227	Zinc metalloprotease (Elastase)
A3L20_RS03260	COG2720	vancomycin resistance protein
A3L20_RS03265	COG1316	TRANSCRIPTIONal
A3L20_RS03270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A3L20_RS03275	COG0346	lactoylglutathione lyase activity
A3L20_RS03280	COG3547	Transposase (IS116 IS110 IS902 family)
A3L20_RS03285	COG1253	flavin adenine dinucleotide binding
A3L20_RS03290	COG1027	Aspartate ammonia-lyase
A3L20_RS03295	COG1620	l-lactate permease
A3L20_RS03310	COG3104	oligopeptide transport
A3L20_RS03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L20_RS03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L20_RS03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L20_RS03340	COG0156	8-amino-7-oxononanoate synthase activity
A3L20_RS03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3L20_RS03355	COG4548	von Willebrand factor, type A
A3L20_RS03360	COG0714	Associated with various cellular activities
A3L20_RS03380	COG0531	amino acid
A3L20_RS03385	COG2188	Transcriptional regulator
A3L20_RS03390	COG1263	PTS System
A3L20_RS03390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3L20_RS03395	COG0366	Alpha amylase catalytic
A3L20_RS03410	COG0697	spore germination
A3L20_RS03415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A3L20_RS03420	COG1115	amino acid carrier protein
A3L20_RS03430	COG1126	abc transporter atp-binding protein
A3L20_RS03435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3L20_RS03440	COG0765	amino acid transport
A3L20_RS03445	COG0765	amino acid transport
A3L20_RS03450	COG0833	amino acid
A3L20_RS03465	COG1595	DNA-templated transcription, initiation
A3L20_RS03475	COG2378	regulation of single-species biofilm formation
A3L20_RS03480	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A3L20_RS03485	COG5002	protein histidine kinase activity
A3L20_RS03500	COG0659	secondary active sulfate transmembrane transporter activity
A3L20_RS03515	COG2271	Major facilitator Superfamily
A3L20_RS03520	COG1846	Transcriptional regulator
A3L20_RS03525	COG0477	Major facilitator Superfamily
A3L20_RS03530	COG1609	Transcriptional regulator
A3L20_RS03535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3L20_RS03550	COG1172	Belongs to the binding-protein-dependent transport system permease family
A3L20_RS03555	COG1879	ABC-type sugar transport system periplasmic component
A3L20_RS03585	COG1063	alcohol dehydrogenase
A3L20_RS03635	COG0840	transmembrane signaling receptor activity
A3L20_RS03640	COG1388	LysM domain
A3L20_RS03640	COG3584	3D domain protein
A3L20_RS03645	COG1476	TRANSCRIPTIONal
A3L20_RS03665	COG3104	oligopeptide transport
A3L20_RS03670	COG1114	Component of the transport system for branched-chain amino acids
A3L20_RS03685	COG1113	amino acid transport
A3L20_RS03690	COG2252	PERMEase
A3L20_RS03705	COG2153	protein acetylation
A3L20_RS03715	COG0569	domain protein
A3L20_RS03715	COG0475	glutathione-regulated potassium exporter activity
A3L20_RS03730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A3L20_RS03740	COG0833	amino acid
A3L20_RS03745	COG4990	cell redox homeostasis
A3L20_RS03760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3L20_RS03765	COG0697	spore germination
A3L20_RS03770	COG0531	amino acid
A3L20_RS03780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A3L20_RS03785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A3L20_RS03790	COG1918	ferrous iron import across plasma membrane
A3L20_RS03790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A3L20_RS03795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A3L20_RS03800	COG0573	inorganic phosphate transmembrane transporter activity
A3L20_RS03805	COG0581	inorganic phosphate transmembrane transporter activity
A3L20_RS03815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A3L20_RS03935	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A3L20_RS03955	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A3L20_RS03960	COG1116	anion transmembrane transporter activity
A3L20_RS03965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A3L20_RS03970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A3L20_RS03975	COG0352	thiamine-phosphate diphosphorylase activity
A3L20_RS03980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3L20_RS03985	COG2104	thiamine diphosphate biosynthetic process
A3L20_RS03995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3L20_RS04000	COG0351	phosphomethylpyrimidine kinase
A3L20_RS04040	COG2205	protein histidine kinase activity
A3L20_RS04045	COG2814	Major facilitator Superfamily
A3L20_RS04050	COG1846	Transcriptional regulator
A3L20_RS04075	COG1136	(ABC) transporter
A3L20_RS04085	COG2252	PERMEase
A3L20_RS04090	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS04105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3L20_RS04110	COG1621	beta-fructofuranosidase activity
A3L20_RS04115	COG1263	PTS System
A3L20_RS04115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3L20_RS04120	COG1609	Transcriptional regulator
A3L20_RS04170	COG0778	Nitroreductase
A3L20_RS04175	COG2719	SpoVR family
A3L20_RS04185	COG3591	Belongs to the peptidase S1B family
A3L20_RS04195	COG1937	Protein conserved in bacteria
A3L20_RS04200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L20_RS04200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A3L20_RS04205	COG0425	Belongs to the sulfur carrier protein TusA family
A3L20_RS04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A3L20_RS04210	COG0425	Belongs to the sulfur carrier protein TusA family
A3L20_RS04220	COG2210	Belongs to the sulfur carrier protein TusA family
A3L20_RS04225	COG0730	response to heat
A3L20_RS04235	COG1316	TRANSCRIPTIONal
A3L20_RS04240	COG0604	alcohol dehydrogenase
A3L20_RS04245	COG1283	sodium-dependent phosphate transmembrane transporter activity
A3L20_RS04260	COG3711	transcriptional antiterminator
A3L20_RS04260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3L20_RS04265	COG1447	Phosphotransferase system cellobiose-specific component IIA
A3L20_RS04270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3L20_RS04295	COG1388	LysM domain
A3L20_RS04295	COG3584	3D domain protein
A3L20_RS04300	COG0577	efflux transmembrane transporter activity
A3L20_RS04305	COG1136	(ABC) transporter
A3L20_RS04315	COG5522	Integral membrane protein (intg_mem_TP0381)
A3L20_RS04330	COG1114	Component of the transport system for branched-chain amino acids
A3L20_RS04335	COG3546	catalase activity
A3L20_RS04375	COG0586	Pfam SNARE associated Golgi protein
A3L20_RS04405	COG0531	amino acid
A3L20_RS04410	COG0475	glutathione-regulated potassium exporter activity
A3L20_RS04420	COG1737	Transcriptional regulator
A3L20_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3L20_RS04430	COG1263	PTS System
A3L20_RS04440	COG2259	Doxx family
A3L20_RS04460	COG1522	sequence-specific DNA binding
A3L20_RS04480	COG1309	transcriptional regulator
A3L20_RS04485	COG2814	Major facilitator Superfamily
A3L20_RS04490	COG2801	Transposase and inactivated derivatives
A3L20_RS04505	COG1132	(ABC) transporter
A3L20_RS04510	COG1131	(ABC) transporter
A3L20_RS04550	COG1136	(ABC) transporter
A3L20_RS04555	COG0577	efflux transmembrane transporter activity
A3L20_RS04560	COG1136	(ABC) transporter
A3L20_RS04565	COG0577	efflux transmembrane transporter activity
A3L20_RS04580	COG1733	regulation of RNA biosynthetic process
A3L20_RS04600	COG0693	protein deglycase activity
A3L20_RS04610	COG0531	amino acid
A3L20_RS04615	COG1012	belongs to the aldehyde dehydrogenase family
A3L20_RS04620	COG1132	(ABC) transporter
A3L20_RS04625	COG1132	(ABC) transporter
A3L20_RS04630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3L20_RS04635	COG0765	amino acid transport
A3L20_RS04640	COG1126	abc transporter atp-binding protein
A3L20_RS04655	COG0189	ligase activity
A3L20_RS04685	COG0028	Belongs to the TPP enzyme family
A3L20_RS04690	COG3527	Alpha-acetolactate decarboxylase
A3L20_RS04705	COG0561	phosphatase activity
A3L20_RS04715	COG5632	N-Acetylmuramoyl-L-alanine amidase
A3L20_RS04715	COG3409	Peptidoglycan-binding domain 1 protein
A3L20_RS04720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A3L20_RS04725	COG0318	PFAM AMP-dependent synthetase and ligase
A3L20_RS04740	COG0659	secondary active sulfate transmembrane transporter activity
A3L20_RS04745	COG2244	polysaccharide biosynthetic process
A3L20_RS04765	COG1024	Enoyl-CoA hydratase
A3L20_RS04785	COG1363	Peptidase, m42
A3L20_RS04820	COG0601	transmembrane transport
A3L20_RS04825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L20_RS04830	COG0444	Belongs to the ABC transporter superfamily
A3L20_RS04835	COG4608	Belongs to the ABC transporter superfamily
A3L20_RS04860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L20_RS04890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3L20_RS04910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3L20_RS04915	COG2814	Major facilitator Superfamily
A3L20_RS04940	COG2801	Transposase and inactivated derivatives
A3L20_RS05065	COG0582	viral genome integration into host DNA
A3L20_RS05070	COG0477	Major facilitator Superfamily
A3L20_RS05075	COG3290	protein histidine kinase activity
A3L20_RS05080	COG4565	transcriptional regulatory protein
A3L20_RS05085	COG3181	Tripartite tricarboxylate transporter family receptor
A3L20_RS05090	COG0494	nUDIX hydrolase
A3L20_RS05095	COG0513	Belongs to the DEAD box helicase family
A3L20_RS05105	COG0305	Participates in initiation and elongation during chromosome replication
A3L20_RS05135	COG0477	Major facilitator Superfamily
A3L20_RS05220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3L20_RS05220	COG3320	Male sterility
A3L20_RS05225	COG1309	transcriptional regulator
A3L20_RS05240	COG1183	phosphatidylcholine synthase activity
A3L20_RS05255	COG2376	Dihydroxyacetone kinase
A3L20_RS05265	COG2376	Dihydroxyacetone kinase
A3L20_RS05275	COG1959	2 iron, 2 sulfur cluster binding
A3L20_RS05300	COG2373	Large extracellular alpha-helical protein
A3L20_RS05345	COG3237	CsbD-like
A3L20_RS05370	COG1191	sigma factor activity
A3L20_RS05380	COG2208	phosphoserine phosphatase activity
A3L20_RS05385	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A3L20_RS05390	COG5002	protein histidine kinase activity
A3L20_RS05390	COG0784	Response regulator, receiver
A3L20_RS05390	COG2205	protein histidine kinase activity
A3L20_RS05425	COG3344	reverse transcriptase
A3L20_RS05435	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A3L20_RS05455	COG0420	3'-5' exonuclease activity
A3L20_RS05460	COG4717	serine-type aminopeptidase activity
A3L20_RS05475	COG1280	lysine exporter protein (LysE YggA)
A3L20_RS05480	COG0346	lactoylglutathione lyase activity
A3L20_RS05485	COG0346	lactoylglutathione lyase activity
A3L20_RS05490	COG0457	Tetratricopeptide repeat
A3L20_RS05500	COG2267	carboxylic ester hydrolase activity
A3L20_RS05525	COG2140	Oxalate decarboxylase
A3L20_RS05530	COG3620	sequence-specific DNA binding
A3L20_RS05535	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A3L20_RS05540	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A3L20_RS05550	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A3L20_RS05560	COG3344	reverse transcriptase
A3L20_RS05570	COG1404	Belongs to the peptidase S8 family
A3L20_RS05600	COG3973	AAA domain
A3L20_RS05625	COG4980	gas vesicle protein
A3L20_RS05630	COG0537	adenosine 5'-monophosphoramidase activity
A3L20_RS05635	COG1131	(ABC) transporter
A3L20_RS05640	COG4473	ABC transporter
A3L20_RS05650	COG1309	transcriptional regulator
A3L20_RS05660	COG3402	PFAM membrane-flanked domain
A3L20_RS05665	COG3428	Bacterial PH domain
A3L20_RS05700	COG0697	spore germination
A3L20_RS05705	COG3402	PFAM membrane-flanked domain
A3L20_RS05710	COG3428	Bacterial PH domain
A3L20_RS05715	COG2329	Antibiotic biosynthesis monooxygenase
A3L20_RS05720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A3L20_RS05735	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A3L20_RS05760	COG1309	transcriptional regulator
A3L20_RS05765	COG1511	domain protein
A3L20_RS05790	COG1609	Transcriptional regulator
A3L20_RS05800	COG1234	tRNA 3'-trailer cleavage
A3L20_RS05805	COG0095	Lipoate-protein ligase
A3L20_RS05815	COG0318	PFAM AMP-dependent synthetase and ligase
A3L20_RS05835	COG1309	transcriptional regulator
A3L20_RS05840	COG1073	alpha beta
A3L20_RS05845	COG1408	metallophosphoesterase
A3L20_RS05850	COG1078	dGTPase activity
A3L20_RS05865	COG1595	DNA-templated transcription, initiation
A3L20_RS05870	COG3708	Transcriptional regulator
A3L20_RS05870	COG2207	Transcriptional regulator
A3L20_RS05880	COG2205	protein histidine kinase activity
A3L20_RS05885	COG0745	RESPONSE REGULATOR receiver
A3L20_RS05905	COG0501	Belongs to the peptidase M48B family
A3L20_RS05910	COG0840	transmembrane signaling receptor activity
A3L20_RS05920	COG2801	Transposase and inactivated derivatives
A3L20_RS05930	COG3693	PFAM glycoside hydrolase, family 10
A3L20_RS05940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A3L20_RS05945	COG2224	Isocitrate lyase
A3L20_RS05960	COG1278	Cold shock
A3L20_RS05975	COG4903	ComK protein
A3L20_RS05980	COG0398	Pfam SNARE associated Golgi protein
A3L20_RS06040	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3L20_RS06065	COG0367	asparagine synthase
A3L20_RS06080	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A3L20_RS06175	COG3331	DNA recombination
A3L20_RS06310	COG4824	toxin secretion phage lysis holin
A3L20_RS06340	COG0367	asparagine synthase
A3L20_RS06350	COG0753	catalase activity
A3L20_RS06355	COG0004	ammonium transporteR
A3L20_RS06380	COG2996	Protein conserved in bacteria
A3L20_RS06390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3L20_RS06405	COG0561	phosphatase activity
A3L20_RS06425	COG2267	carboxylic ester hydrolase activity
A3L20_RS06440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A3L20_RS06445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A3L20_RS06450	COG5504	Zn-dependent protease
A3L20_RS06465	COG0180	Tryptophanyl-tRNA synthetase
A3L20_RS06475	COG4166	transmembrane transport
A3L20_RS06480	COG0601	transmembrane transport
A3L20_RS06485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L20_RS06490	COG0444	Belongs to the ABC transporter superfamily
A3L20_RS06495	COG4608	Belongs to the ABC transporter superfamily
A3L20_RS06500	COG0534	Mate efflux family protein
A3L20_RS06505	COG4166	transmembrane transport
A3L20_RS06520	COG0861	Integral membrane protein TerC family
A3L20_RS06530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A3L20_RS06540	COG1164	Oligoendopeptidase f
A3L20_RS06550	COG2346	COG2346, Truncated hemoglobins
A3L20_RS06555	COG4116	CYTH
A3L20_RS06565	COG2357	RelA SpoT domain protein
A3L20_RS06575	COG0564	pseudouridine synthase activity
A3L20_RS06590	COG0772	Belongs to the SEDS family
A3L20_RS06595	COG1216	Glycosyl transferase, family 2
A3L20_RS06615	COG0463	Glycosyl transferase, family 2
A3L20_RS06615	COG0457	Tetratricopeptide repeat
A3L20_RS06635	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A3L20_RS06650	COG1091	dTDP-4-dehydrorhamnose reductase activity
A3L20_RS06695	COG2153	protein acetylation
A3L20_RS06705	COG2382	esterase
A3L20_RS06720	COG5492	domain, Protein
A3L20_RS06725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3L20_RS06740	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A3L20_RS06740	COG0512	Glutamine amidotransferase of anthranilate synthase
A3L20_RS06775	COG1620	l-lactate permease
A3L20_RS06780	COG5634	Uncharacterized conserved protein (DUF2278)
A3L20_RS06835	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3L20_RS06845	COG1476	TRANSCRIPTIONal
A3L20_RS06880	COG4152	abc transporter atp-binding protein
A3L20_RS06905	COG2226	methyltransferase
A3L20_RS06915	COG1686	Belongs to the peptidase S11 family
A3L20_RS06920	COG0681	Belongs to the peptidase S26 family
A3L20_RS06955	COG1012	belongs to the aldehyde dehydrogenase family
A3L20_RS06965	COG1176	ABC-type spermidine putrescine transport system, permease component I
A3L20_RS06970	COG1177	transmembrane transport
A3L20_RS06980	COG0671	phosphoesterase, PA-phosphatase related
A3L20_RS06985	COG2409	Drug exporters of the RND superfamily
A3L20_RS06995	COG0564	pseudouridine synthase activity
A3L20_RS07010	COG2340	Cysteine-rich secretory protein family
A3L20_RS07015	COG0247	lactate metabolic process
A3L20_RS07020	COG0277	FAD linked oxidase domain protein
A3L20_RS07025	COG3835	regulator
A3L20_RS07035	COG0745	RESPONSE REGULATOR receiver
A3L20_RS07040	COG5002	protein histidine kinase activity
A3L20_RS07045	COG2186	Transcriptional regulator
A3L20_RS07065	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A3L20_RS07075	COG2116	formate transmembrane transporter activity
A3L20_RS07080	COG0861	Integral membrane protein TerC family
A3L20_RS07085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A3L20_RS07095	COG2030	dehydratase
A3L20_RS07115	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS07120	COG3243	poly(R)-hydroxyalkanoic acid synthase
A3L20_RS07130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A3L20_RS07145	COG1840	ABC-type Fe3 transport system, periplasmic component
A3L20_RS07150	COG3842	ATPase activity
A3L20_RS07175	COG1349	DNA-binding transcription factor activity
A3L20_RS07190	COG0235	Class ii aldolase
A3L20_RS07200	COG2861	carbohydrate metabolic process
A3L20_RS07210	COG3852	Histidine kinase
A3L20_RS07215	COG1846	Transcriptional regulator
A3L20_RS07225	COG2318	DinB family
A3L20_RS07235	COG5002	protein histidine kinase activity
A3L20_RS07245	COG0720	synthase
A3L20_RS07260	COG4873	Protein conserved in bacteria
A3L20_RS07290	COG1780	Probably involved in ribonucleotide reductase function
A3L20_RS07295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3L20_RS07300	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3L20_RS07305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3L20_RS07310	COG1725	Transcriptional regulator
A3L20_RS07315	COG1131	(ABC) transporter
A3L20_RS07325	COG1131	(ABC) transporter
A3L20_RS07345	COG1522	sequence-specific DNA binding
A3L20_RS07355	COG1335	isochorismatase
A3L20_RS07365	COG1619	proteins homologs of microcin C7 resistance protein MccF
A3L20_RS07370	COG2070	2-Nitropropane dioxygenase
A3L20_RS07375	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A3L20_RS07385	COG1696	Membrane protein involved in D-alanine export
A3L20_RS07410	COG0716	FMN binding
A3L20_RS07465	COG1846	Transcriptional regulator
A3L20_RS07475	COG1301	dicarboxylic acid transport
A3L20_RS07480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A3L20_RS07485	COG4709	membrane
A3L20_RS07490	COG3874	Sporulation protein YtfJ
A3L20_RS07510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A3L20_RS07515	COG0028	Belongs to the TPP enzyme family
A3L20_RS07520	COG0440	acetolactate synthase activity
A3L20_RS07595	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A3L20_RS07615	COG1183	phosphatidylcholine synthase activity
A3L20_RS07620	COG1368	sulfuric ester hydrolase activity
A3L20_RS07630	COG0019	diaminopimelate decarboxylase activity
A3L20_RS07650	COG0529	Catalyzes the synthesis of activated sulfate
A3L20_RS07655	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3L20_RS07675	COG1648	precorrin-2 dehydrogenase activity
A3L20_RS07680	COG0733	neurotransmitter:sodium symporter activity
A3L20_RS07700	COG1757	Na H antiporter
A3L20_RS07715	COG4758	membrane
A3L20_RS07720	COG4585	Histidine kinase
A3L20_RS07725	COG2197	response regulator
A3L20_RS07735	COG1114	Component of the transport system for branched-chain amino acids
A3L20_RS07785	COG0730	response to heat
A3L20_RS07790	COG0306	phosphate transporter
A3L20_RS07795	COG1392	Phosphate transport regulator
A3L20_RS07815	COG3852	Histidine kinase
A3L20_RS07820	COG1801	Protein of unknown function DUF72
A3L20_RS07830	COG0582	viral genome integration into host DNA
A3L20_RS07835	COG5002	protein histidine kinase activity
A3L20_RS07850	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A3L20_RS07850	COG0392	lysyltransferase activity
A3L20_RS07865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A3L20_RS07870	COG1686	Belongs to the peptidase S11 family
A3L20_RS07875	COG2715	membrane protein required for spore maturation
A3L20_RS07880	COG0700	Nucleoside recognition
A3L20_RS07885	COG1187	pseudouridine synthase activity
A3L20_RS07895	COG1333	cytochrome c biogenesis protein
A3L20_RS07900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A3L20_RS07905	COG0745	RESPONSE REGULATOR receiver
A3L20_RS07910	COG5002	protein histidine kinase activity
A3L20_RS07915	COG2096	Adenosyltransferase
A3L20_RS07930	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A3L20_RS07935	COG1141	Ferredoxin
A3L20_RS07945	COG0514	ATP-dependent DNA helicase (RecQ)
A3L20_RS07950	COG1266	CAAX protease self-immunity
A3L20_RS07960	COG1408	metallophosphoesterase
A3L20_RS07965	COG0789	Transcriptional regulator
A3L20_RS07975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A3L20_RS07995	COG0492	ferredoxin-NADP+ reductase activity
A3L20_RS08000	COG0252	asparaginase activity
A3L20_RS08070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A3L20_RS08085	COG0142	geranyltranstransferase activity
A3L20_RS08095	COG0142	geranyltranstransferase activity
A3L20_RS08120	COG0457	Tetratricopeptide repeat
A3L20_RS08140	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A3L20_RS08145	COG2010	Cytochrome c
A3L20_RS08145	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A3L20_RS08150	COG4347	Protein of unknown function (DUF1405)
A3L20_RS08165	COG2738	Putative neutral zinc metallopeptidase
A3L20_RS08175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3L20_RS08180	COG1694	Mazg nucleotide pyrophosphohydrolase
A3L20_RS08200	COG0438	transferase activity, transferring glycosyl groups
A3L20_RS08235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A3L20_RS08235	COG1199	ATP-dependent helicase activity
A3L20_RS08255	COG3935	DnaD domain protein
A3L20_RS08260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A3L20_RS08270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A3L20_RS08270	COG4499	WXG100 protein secretion system (Wss), protein YukC
A3L20_RS08330	COG0116	Belongs to the methyltransferase superfamily
A3L20_RS08340	COG1199	ATP-dependent helicase activity
A3L20_RS08345	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A3L20_RS08350	COG2801	Transposase and inactivated derivatives
A3L20_RS08365	COG3173	Aminoglycoside phosphotransferase
A3L20_RS08375	COG0024	Methionine aminopeptidase
A3L20_RS08385	COG2233	PERMEase
A3L20_RS08390	COG2311	Membrane
A3L20_RS08395	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A3L20_RS08405	COG0456	acetyltransferase
A3L20_RS08440	COG0754	glutathionylspermidine amidase activity
A3L20_RS08455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A3L20_RS08480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A3L20_RS08495	COG1215	transferase activity, transferring glycosyl groups
A3L20_RS08525	COG0454	-acetyltransferase
A3L20_RS08545	COG0328	RNA-DNA hybrid ribonuclease activity
A3L20_RS08580	COG3403	YqcI/YcgG family
A3L20_RS08585	COG1280	lysine exporter protein (LysE YggA)
A3L20_RS08605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3L20_RS08610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A3L20_RS08620	COG0475	glutathione-regulated potassium exporter activity
A3L20_RS08625	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A3L20_RS08630	COG4978	Transcriptional regulator
A3L20_RS08630	COG0789	Transcriptional regulator
A3L20_RS08640	COG2323	membrane
A3L20_RS08645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A3L20_RS08675	COG1923	regulation of RNA biosynthetic process
A3L20_RS08685	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A3L20_RS08690	COG1360	Flagellar Motor Protein
A3L20_RS08695	COG2201	protein-glutamate methylesterase activity
A3L20_RS08700	COG2198	Histidine kinase
A3L20_RS08700	COG0643	Histidine kinase
A3L20_RS08705	COG1776	CheC inhibitor of MCP methylation
A3L20_RS08705	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A3L20_RS08720	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A3L20_RS08740	COG1256	bacterial-type flagellum assembly
A3L20_RS08745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A3L20_RS08750	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A3L20_RS08765	COG1815	bacterial-type flagellum-dependent cell motility
A3L20_RS08770	COG1558	bacterial-type flagellum-dependent cell motility
A3L20_RS08780	COG1766	The M ring may be actively involved in energy transduction
A3L20_RS08785	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A3L20_RS08795	COG1157	protein secretion by the type III secretion system
A3L20_RS08815	COG1749	Flagellar hook protein flgE
A3L20_RS08830	COG0835	chemotaxis
A3L20_RS08830	COG0784	Response regulator, receiver
A3L20_RS08840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A3L20_RS08845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A3L20_RS08850	COG0741	lytic transglycosylase activity
A3L20_RS08860	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A3L20_RS08865	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A3L20_RS08865	COG1776	CheC inhibitor of MCP methylation
A3L20_RS08875	COG1338	Plays a role in the flagellum-specific transport system
A3L20_RS08880	COG1987	bacterial-type flagellum assembly
A3L20_RS08890	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A3L20_RS08895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A3L20_RS08900	COG1419	protein localization to endoplasmic reticulum
A3L20_RS08905	COG4786	Flagellar basal body rod
A3L20_RS08910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3L20_RS08915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L20_RS08945	COG2329	Antibiotic biosynthesis monooxygenase
A3L20_RS08950	COG1215	transferase activity, transferring glycosyl groups
A3L20_RS08975	COG0583	DNA-binding transcription factor activity
A3L20_RS08980	COG3842	ATPase activity
A3L20_RS09030	COG0406	alpha-ribazole phosphatase activity
A3L20_RS09050	COG1846	Transcriptional regulator
A3L20_RS09060	COG0367	asparagine synthase
A3L20_RS09095	COG0523	cobalamin synthesis protein
A3L20_RS09100	COG0701	Predicted permease
A3L20_RS09110	COG1216	Glycosyl transferase, family 2
A3L20_RS09110	COG0438	transferase activity, transferring glycosyl groups
A3L20_RS09115	COG1757	Na H antiporter
A3L20_RS09120	COG0789	Transcriptional regulator
A3L20_RS09155	COG0534	Mate efflux family protein
A3L20_RS09160	COG3340	Belongs to the peptidase S51 family
A3L20_RS09180	COG0785	Cytochrome C biogenesis protein
A3L20_RS09185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3L20_RS09210	COG2733	membrane
A3L20_RS09245	COG1131	(ABC) transporter
A3L20_RS09260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A3L20_RS09265	COG0528	UMP kinase activity
A3L20_RS09275	COG1027	Aspartate ammonia-lyase
A3L20_RS09280	COG0281	malic enzyme
A3L20_RS09285	COG4191	Histidine kinase
A3L20_RS09290	COG0784	Response regulator, receiver
A3L20_RS09295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A3L20_RS09345	COG2814	Major facilitator Superfamily
A3L20_RS09360	COG1695	Transcriptional regulator
A3L20_RS09370	COG0477	Major facilitator Superfamily
A3L20_RS09380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A3L20_RS09390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3L20_RS09410	COG0733	neurotransmitter:sodium symporter activity
A3L20_RS09420	COG5566	PFAM Mor transcription activator
A3L20_RS09425	COG2323	membrane
A3L20_RS09445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3L20_RS09455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A3L20_RS09460	COG0028	Belongs to the TPP enzyme family
A3L20_RS09480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A3L20_RS09505	COG2814	Major facilitator Superfamily
A3L20_RS09510	COG3384	dioxygenase
A3L20_RS09525	COG3279	Response regulator of the LytR AlgR family
A3L20_RS09530	COG0427	acetyl-CoA hydrolase
A3L20_RS09550	COG4166	transmembrane transport
A3L20_RS09555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L20_RS09560	COG1914	H( )-stimulated, divalent metal cation uptake system
A3L20_RS09575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A3L20_RS09585	COG0531	amino acid
A3L20_RS09605	COG2309	aminopeptidase activity
A3L20_RS09620	COG0456	acetyltransferase
A3L20_RS09635	COG1309	transcriptional regulator
A3L20_RS09640	COG2390	Transcriptional regulator
A3L20_RS09650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A3L20_RS09655	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A3L20_RS09695	COG4846	Membrane protein involved in cytochrome C biogenesis
A3L20_RS09705	COG0006	proline dipeptidase activity
A3L20_RS09715	COG2132	Multicopper oxidase
A3L20_RS09725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3L20_RS09745	COG1114	Component of the transport system for branched-chain amino acids
A3L20_RS09755	COG1276	copper resistance
A3L20_RS09755	COG2372	response to copper ion
A3L20_RS09760	COG4549	nuclear export factor GLE1
A3L20_RS09765	COG0697	spore germination
A3L20_RS09770	COG0583	DNA-binding transcription factor activity
A3L20_RS09775	COG1959	2 iron, 2 sulfur cluster binding
A3L20_RS09780	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A3L20_RS09785	COG0778	Nitroreductase
A3L20_RS09800	COG0628	permease
A3L20_RS09810	COG1231	oxidoreductase activity
A3L20_RS09815	COG0523	cobalamin synthesis protein
A3L20_RS09825	COG0411	ABC transporter
A3L20_RS09845	COG0583	DNA-binding transcription factor activity
A3L20_RS09855	COG1942	4-Oxalocrotonate Tautomerase
A3L20_RS09875	COG1271	oxidase subunit
A3L20_RS09880	COG1294	oxidase, subunit
A3L20_RS09885	COG4988	ABC transporter
A3L20_RS09890	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A3L20_RS09900	COG1216	Glycosyl transferase, family 2
A3L20_RS09940	COG1686	Belongs to the peptidase S11 family
A3L20_RS09955	COG0791	NLP P60 protein
A3L20_RS09955	COG1388	LysM domain
A3L20_RS09965	COG1132	(ABC) transporter
A3L20_RS10040	COG3646	Phage regulatory protein
A3L20_RS10040	COG3645	SOS response
A3L20_RS10065	COG0305	Participates in initiation and elongation during chromosome replication
A3L20_RS10225	COG1132	(ABC) transporter
A3L20_RS10230	COG0745	RESPONSE REGULATOR receiver
A3L20_RS10235	COG5002	protein histidine kinase activity
A3L20_RS10240	COG0300	oxidoreductase activity
A3L20_RS10275	COG3547	Transposase (IS116 IS110 IS902 family)
A3L20_RS10280	COG0460	homoserine dehydrogenase
A3L20_RS10305	COG1316	TRANSCRIPTIONal
A3L20_RS10320	COG1285	pathogenesis
A3L20_RS10330	COG2801	Transposase and inactivated derivatives
A3L20_RS10335	COG1247	-acetyltransferase
A3L20_RS10355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3L20_RS10365	COG1082	Xylose isomerase domain protein TIM barrel
A3L20_RS10375	COG2814	Major facilitator Superfamily
A3L20_RS10380	COG1279	arginine transmembrane transporter activity
A3L20_RS10385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L20_RS10395	COG1752	Esterase of the alpha-beta hydrolase superfamily
A3L20_RS10425	COG0577	efflux transmembrane transporter activity
A3L20_RS10430	COG2002	toxin-antitoxin pair type II binding
A3L20_RS10435	COG1404	Belongs to the peptidase S8 family
A3L20_RS10440	COG0640	Transcriptional regulator
A3L20_RS10445	COG0667	Aldo Keto reductase
A3L20_RS10450	COG2814	Major facilitator Superfamily
A3L20_RS10480	COG0840	transmembrane signaling receptor activity
A3L20_RS10495	COG3949	Membrane
A3L20_RS10500	COG0783	Belongs to the Dps family
A3L20_RS10515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3L20_RS10525	COG1231	oxidoreductase activity
A3L20_RS10530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L20_RS10535	COG4989	oxidoreductase activity
A3L20_RS10540	COG0523	cobalamin synthesis protein
A3L20_RS10545	COG0456	acetyltransferase
A3L20_RS10550	COG0803	Belongs to the bacterial solute-binding protein 9 family
A3L20_RS10565	COG0702	epimerase
A3L20_RS10575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3L20_RS10585	COG4166	transmembrane transport
A3L20_RS10600	COG0406	alpha-ribazole phosphatase activity
A3L20_RS10610	COG5337	Spore coat protein CotH
A3L20_RS10620	COG0586	Pfam SNARE associated Golgi protein
A3L20_RS10625	COG2244	polysaccharide biosynthetic process
A3L20_RS10635	COG0701	Predicted permease
A3L20_RS10640	COG3689	TIGRFAM TIGR03943 family protein
A3L20_RS10645	COG1607	acyl-coa hydrolase
A3L20_RS10650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A3L20_RS10665	COG0702	epimerase
A3L20_RS10670	COG2839	Protein conserved in bacteria
A3L20_RS10675	COG1253	flavin adenine dinucleotide binding
A3L20_RS10700	COG2801	Transposase and inactivated derivatives
A3L20_RS10705	COG2963	transposase activity
A3L20_RS10710	COG1114	Component of the transport system for branched-chain amino acids
A3L20_RS10715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L20_RS10730	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3L20_RS10740	COG1876	peptidase activity
A3L20_RS10755	COG2211	Major facilitator Superfamily
A3L20_RS10770	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3L20_RS10780	COG0561	phosphatase activity
A3L20_RS10810	COG3646	Phage regulatory protein
A3L20_RS10870	COG0582	viral genome integration into host DNA
A3L20_RS10920	COG1802	Transcriptional regulator
A3L20_RS10920	COG4626	Terminase
A3L20_RS10925	COG3547	Transposase (IS116 IS110 IS902 family)
A3L20_RS10935	COG0740	serine-type endopeptidase activity
A3L20_RS10985	COG3344	reverse transcriptase
A3L20_RS11010	COG4824	toxin secretion phage lysis holin
A3L20_RS11015	COG1388	LysM domain
A3L20_RS11015	COG5632	N-Acetylmuramoyl-L-alanine amidase
A3L20_RS11015	COG3409	Peptidoglycan-binding domain 1 protein
A3L20_RS11055	COG0561	phosphatase activity
A3L20_RS11060	COG1846	Transcriptional regulator
A3L20_RS11065	COG2814	Major facilitator Superfamily
A3L20_RS11075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A3L20_RS11080	COG4106	trans-aconitate 2-methyltransferase activity
A3L20_RS11095	COG1819	glycosyl
A3L20_RS11100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3L20_RS11105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L20_RS11135	COG0456	acetyltransferase
A3L20_RS11240	COG3874	Sporulation protein YtfJ
A3L20_RS11265	COG2226	methyltransferase
A3L20_RS11285	COG1082	Xylose isomerase domain protein TIM barrel
A3L20_RS11290	COG0346	lactoylglutathione lyase activity
A3L20_RS11300	COG0604	alcohol dehydrogenase
A3L20_RS11305	COG1595	DNA-templated transcription, initiation
A3L20_RS11315	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3L20_RS11325	COG0426	domain, Protein
A3L20_RS11325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A3L20_RS11335	COG0386	Belongs to the glutathione peroxidase family
A3L20_RS11340	COG1305	Transglutaminase-like
A3L20_RS11345	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A3L20_RS11350	COG0714	Associated with various cellular activities
A3L20_RS11355	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A3L20_RS11360	COG1140	nitrate reductase beta subunit
A3L20_RS11365	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A3L20_RS11370	COG2181	nitrate reductase activity
A3L20_RS11375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3L20_RS11380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L20_RS11385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3L20_RS11390	COG0303	'Molybdopterin
A3L20_RS11395	COG0314	molybdopterin synthase activity
A3L20_RS11405	COG2223	nitrite transmembrane transporter activity
A3L20_RS11420	COG1648	precorrin-2 dehydrogenase activity
A3L20_RS11425	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
A3L20_RS11430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A3L20_RS11430	COG1587	Uroporphyrinogen-III synthase
A3L20_RS11435	COG2146	nitrite reductase [NAD(P)H] activity
A3L20_RS11440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3L20_RS11445	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
A3L20_RS11480	COG2359	stage V sporulation protein S
A3L20_RS11495	COG0457	Tetratricopeptide repeat
A3L20_RS11510	COG1418	mRNA catabolic process
A3L20_RS11515	COG0488	(ABC) transporter
A3L20_RS11535	COG0629	single-stranded DNA binding
A3L20_RS11550	COG1413	lyase activity
A3L20_RS11565	COG2136	Putative SAM-dependent methyltransferase
A3L20_RS11565	COG2521	methyltransferase
A3L20_RS11570	COG0018	arginyl-trna synthetase
A3L20_RS11605	COG0733	neurotransmitter:sodium symporter activity
A3L20_RS11630	COG2610	gluconate transmembrane transporter activity
A3L20_RS11640	COG1794	racemase activity, acting on amino acids and derivatives
A3L20_RS11650	COG0456	acetyltransferase
A3L20_RS11665	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A3L20_RS11675	COG1131	(ABC) transporter
A3L20_RS11690	COG0546	phosphoglycolate phosphatase activity
A3L20_RS11705	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3L20_RS11720	COG0768	penicillin binding
A3L20_RS11730	COG0204	Acyl-transferase
A3L20_RS11735	COG1272	protein, Hemolysin III
A3L20_RS11745	COG0805	protein transport
A3L20_RS11755	COG1307	EDD domain protein, DegV family
A3L20_RS11765	COG1999	signal sequence binding
A3L20_RS11770	COG0071	Belongs to the small heat shock protein (HSP20) family
A3L20_RS11775	COG0367	asparagine synthase
A3L20_RS11790	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3L20_RS11795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L20_RS11800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A3L20_RS11820	COG1335	isochorismatase
A3L20_RS11825	COG1051	belongs to the nudix hydrolase family
A3L20_RS11830	COG0668	transmembrane transport
A3L20_RS11835	COG2203	Gaf domain
A3L20_RS11835	COG4585	Histidine kinase
A3L20_RS11840	COG2197	response regulator
A3L20_RS11845	COG1737	Transcriptional regulator
A3L20_RS11850	COG0384	phenazine biosynthesis protein PhzF
A3L20_RS11855	COG1064	alcohol dehydrogenase
A3L20_RS11870	COG1070	Carbohydrate kinase
A3L20_RS11880	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A3L20_RS11915	COG1125	glycine betaine transport
A3L20_RS11915	COG0517	IMP dehydrogenase activity
A3L20_RS11920	COG1174	glycine betaine transport
A3L20_RS11955	COG1253	flavin adenine dinucleotide binding
A3L20_RS11960	COG1012	belongs to the aldehyde dehydrogenase family
A3L20_RS11965	COG5506	Protein of unknown function (DUF1694)
A3L20_RS11980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A3L20_RS11985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A3L20_RS11990	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A3L20_RS11995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L20_RS12000	COG0456	acetyltransferase
A3L20_RS12005	COG3829	transcription factor binding
A3L20_RS12010	COG1509	lysine 2,3-aminomutase activity
A3L20_RS12040	COG4991	sh3 domain protein
A3L20_RS12040	COG3064	Membrane
A3L20_RS12040	COG0515	serine threonine protein kinase
A3L20_RS12050	COG0671	phosphoesterase, PA-phosphatase related
A3L20_RS12055	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A3L20_RS12060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3L20_RS12155	COG0300	oxidoreductase activity
A3L20_RS12175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A3L20_RS12175	COG4499	WXG100 protein secretion system (Wss), protein YukC
A3L20_RS12185	COG2814	Major facilitator Superfamily
A3L20_RS12190	COG4841	protein insertion into membrane
A3L20_RS12195	COG0372	Belongs to the citrate synthase family
A3L20_RS12200	COG2079	MmgE PrpD family protein
A3L20_RS12205	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A3L20_RS12210	COG1960	acyl-CoA dehydrogenase activity
A3L20_RS12215	COG2084	Dehydrogenase
A3L20_RS12225	COG1280	lysine exporter protein (LysE YggA)
A3L20_RS12230	COG1024	Enoyl-CoA hydratase
A3L20_RS12245	COG0420	3'-5' exonuclease activity
A3L20_RS12250	COG0419	ATPase involved in DNA repair
A3L20_RS12270	COG2223	nitrite transmembrane transporter activity
A3L20_RS12275	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS12280	COG1169	isochorismate synthase
A3L20_RS12285	COG1021	2,3-dihydroxybenzoate-AMP ligase
A3L20_RS12290	COG3433	isochorismatase activity
A3L20_RS12290	COG1535	isochorismatase
A3L20_RS12295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3L20_RS12300	COG3251	PFAM MbtH domain protein
A3L20_RS12305	COG2814	Major facilitator Superfamily
A3L20_RS12320	COG0776	regulation of translation
A3L20_RS12330	COG2318	DinB family
A3L20_RS12340	COG1115	amino acid carrier protein
A3L20_RS12360	COG1187	pseudouridine synthase activity
A3L20_RS12365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A3L20_RS12370	COG1136	(ABC) transporter
A3L20_RS12410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3L20_RS12425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L20_RS12460	COG1247	-acetyltransferase
A3L20_RS12485	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A3L20_RS12495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L20_RS12525	COG0583	DNA-binding transcription factor activity
A3L20_RS12530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A3L20_RS12540	COG0583	DNA-binding transcription factor activity
A3L20_RS12545	COG2258	MOSC domain
A3L20_RS12560	COG1132	(ABC) transporter
A3L20_RS12565	COG1132	(ABC) transporter
A3L20_RS12590	COG1396	sequence-specific DNA binding
A3L20_RS12620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A3L20_RS12625	COG1595	DNA-templated transcription, initiation
A3L20_RS12655	COG1649	PFAM Uncharacterised BCR, COG1649
A3L20_RS12680	COG2971	BadF BadG BcrA BcrD
A3L20_RS12690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A3L20_RS12700	COG1846	Transcriptional regulator
A3L20_RS12715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L20_RS12735	COG1309	transcriptional regulator
A3L20_RS12770	COG3344	reverse transcriptase
A3L20_RS12840	COG3344	reverse transcriptase
A3L20_RS12850	COG0500	methyltransferase
A3L20_RS12850	COG3615	Tellurite resistance protein tehB
A3L20_RS12860	COG2226	methyltransferase
A3L20_RS12865	COG3961	Belongs to the TPP enzyme family
A3L20_RS12900	COG2195	Cleaves the N-terminal amino acid of tripeptides
A3L20_RS12925	COG2002	toxin-antitoxin pair type II binding
A3L20_RS12935	COG0730	response to heat
A3L20_RS12945	COG1686	Belongs to the peptidase S11 family
A3L20_RS12960	COG2814	Major facilitator Superfamily
A3L20_RS12990	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS13035	COG0741	lytic transglycosylase activity
A3L20_RS13045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L20_RS13055	COG0456	acetyltransferase
A3L20_RS13065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A3L20_RS13070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3L20_RS13075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A3L20_RS13090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A3L20_RS13100	COG2234	aminopeptidase activity
A3L20_RS13105	COG2814	Major facilitator Superfamily
A3L20_RS13155	COG1396	sequence-specific DNA binding
A3L20_RS13175	COG1309	transcriptional regulator
A3L20_RS13180	COG0367	asparagine synthase
A3L20_RS13185	COG4585	Histidine kinase
A3L20_RS13195	COG1404	Belongs to the peptidase S8 family
A3L20_RS13245	COG0768	penicillin binding
A3L20_RS13250	COG1595	DNA-templated transcription, initiation
A3L20_RS13260	COG0768	penicillin binding
A3L20_RS13265	COG0768	penicillin binding
A3L20_RS13275	COG1408	metallophosphoesterase
A3L20_RS13285	COG1131	(ABC) transporter
A3L20_RS13295	COG1309	transcriptional regulator
A3L20_RS13310	COG1960	acyl-CoA dehydrogenase activity
A3L20_RS13315	COG0439	Biotin carboxylase
A3L20_RS13320	COG0511	ligase activity, forming carbon-carbon bonds
A3L20_RS13325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A3L20_RS13330	COG1024	Enoyl-CoA hydratase
A3L20_RS13335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3L20_RS13340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A3L20_RS13350	COG3547	Transposase (IS116 IS110 IS902 family)
A3L20_RS13365	COG0572	uridine kinase
A3L20_RS13370	COG2318	DinB family
A3L20_RS13375	COG1686	Belongs to the peptidase S11 family
A3L20_RS13405	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A3L20_RS13420	COG3227	Zinc metalloprotease (Elastase)
A3L20_RS13425	COG2207	Transcriptional regulator
A3L20_RS13455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A3L20_RS13465	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS13470	COG1733	regulation of RNA biosynthetic process
A3L20_RS13505	COG2801	Transposase and inactivated derivatives
A3L20_RS13525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L20_RS13535	COG2801	Transposase and inactivated derivatives
A3L20_RS13550	COG1063	alcohol dehydrogenase
A3L20_RS13560	COG2323	membrane
A3L20_RS13570	COG0693	protein deglycase activity
A3L20_RS13580	COG3386	PFAM SMP-30 Gluconolaconase
A3L20_RS13585	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
A3L20_RS13590	COG3773	Cell wall hydrolase
A3L20_RS13600	COG0745	RESPONSE REGULATOR receiver
A3L20_RS13610	COG3344	reverse transcriptase
A3L20_RS13615	COG2205	protein histidine kinase activity
A3L20_RS13620	COG0583	DNA-binding transcription factor activity
A3L20_RS13625	COG0667	Aldo Keto reductase
A3L20_RS13630	COG0488	(ABC) transporter
A3L20_RS13645	COG1136	(ABC) transporter
A3L20_RS13650	COG0577	efflux transmembrane transporter activity
A3L20_RS13675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L20_RS13685	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A3L20_RS13710	COG0582	viral genome integration into host DNA
A3L20_RS13720	COG1396	sequence-specific DNA binding
A3L20_RS13740	COG0740	serine-type endopeptidase activity
A3L20_RS13805	COG3547	Transposase (IS116 IS110 IS902 family)
A3L20_RS13815	COG5632	N-Acetylmuramoyl-L-alanine amidase
A3L20_RS13820	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A3L20_RS13865	COG2124	cytochrome p450
A3L20_RS13900	COG0561	phosphatase activity
A3L20_RS13905	COG5002	protein histidine kinase activity
A3L20_RS13910	COG0768	penicillin binding
A3L20_RS13920	COG1819	glycosyl
A3L20_RS13925	COG1794	racemase activity, acting on amino acids and derivatives
A3L20_RS13945	COG2205	protein histidine kinase activity
A3L20_RS13995	COG2169	Transcriptional regulator
A3L20_RS14020	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A3L20_RS14025	COG0604	alcohol dehydrogenase
A3L20_RS14030	COG0671	phosphoesterase, PA-phosphatase related
A3L20_RS14035	COG0768	penicillin binding
A3L20_RS14095	COG0584	glycerophosphoryl diester phosphodiesterase
A3L20_RS14115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L20_RS14120	COG0697	spore germination
A3L20_RS14145	COG0494	nUDIX hydrolase
A3L20_RS14155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3L20_RS14165	COG2223	nitrite transmembrane transporter activity
A3L20_RS14175	COG2801	Transposase and inactivated derivatives
A3L20_RS14190	COG0592	DNA-directed DNA polymerase activity
A3L20_RS14195	COG1051	belongs to the nudix hydrolase family
A3L20_RS14205	COG2801	Transposase and inactivated derivatives
A3L20_RS14230	COG3878	Protein conserved in bacteria
A3L20_RS14250	COG4667	esterase of the alpha-beta hydrolase superfamily
A3L20_RS14290	COG0322	excinuclease ABC activity
A3L20_RS14325	COG1819	glycosyl
A3L20_RS14330	COG1819	glycosyl
A3L20_RS14345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3L20_RS14380	COG0745	RESPONSE REGULATOR receiver
A3L20_RS14385	COG5002	protein histidine kinase activity
A3L20_RS14400	COG1136	(ABC) transporter
A3L20_RS14405	COG0577	efflux transmembrane transporter activity
A3L20_RS14410	COG1073	alpha beta
A3L20_RS14415	COG0657	acetylesterase activity
A3L20_RS14420	COG0076	glutamate decarboxylase activity
A3L20_RS14435	COG1523	belongs to the glycosyl hydrolase 13 family
A3L20_RS14440	COG3227	Zinc metalloprotease (Elastase)
A3L20_RS14445	COG0737	Belongs to the 5'-nucleotidase family
A3L20_RS14465	COG0201	protein transport
A3L20_RS14470	COG0697	spore germination
A3L20_RS14475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L20_RS14510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L20_RS14525	COG2959	enzyme of heme biosynthesis
A3L20_RS14565	COG1309	transcriptional regulator
A3L20_RS14580	COG3284	Transcriptional regulator
A3L20_RS14595	COG1349	DNA-binding transcription factor activity
A3L20_RS14610	COG1959	2 iron, 2 sulfur cluster binding
A3L20_RS14625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A3L20_RS14765	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A3L20_RS14765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A3L20_RS14925	COG1783	phage Terminase large subunit
A3L20_RS14950	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3L20_RS14955	COG0022	dehydrogenase e1 component
A3L20_RS14960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A3L20_RS14970	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS15000	COG4176	ABC-type proline glycine betaine transport system permease component
A3L20_RS15005	COG4175	Glycine betaine
A3L20_RS15005	COG0517	IMP dehydrogenase activity
A3L20_RS15035	COG2153	protein acetylation
A3L20_RS15055	COG3397	chitin binding
A3L20_RS15070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A3L20_RS15080	COG2205	protein histidine kinase activity
A3L20_RS15085	COG2226	methyltransferase
A3L20_RS15090	COG2315	Protein conserved in bacteria
A3L20_RS15140	COG0456	acetyltransferase
A3L20_RS15145	COG3973	AAA domain
A3L20_RS15155	COG2105	PFAM AIG2 family protein
A3L20_RS15160	COG0514	ATP-dependent DNA helicase (RecQ)
A3L20_RS15185	COG2801	Transposase and inactivated derivatives
A3L20_RS15210	COG4637	Psort location Cytoplasmic, score
A3L20_RS15225	COG3397	chitin binding
A3L20_RS15240	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A3L20_RS15245	COG1115	amino acid carrier protein
A3L20_RS15250	COG1012	belongs to the aldehyde dehydrogenase family
A3L20_RS15255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3L20_RS15265	COG3938	Belongs to the proline racemase family
A3L20_RS15270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3L20_RS15310	COG0586	Pfam SNARE associated Golgi protein
A3L20_RS15320	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A3L20_RS15325	COG4166	transmembrane transport
A3L20_RS15335	COG4948	Mandelate Racemase Muconate Lactonizing
A3L20_RS15350	COG0667	Aldo Keto reductase
A3L20_RS15395	COG5002	protein histidine kinase activity
A3L20_RS15395	COG3850	Histidine kinase
A3L20_RS15400	COG0745	RESPONSE REGULATOR receiver
A3L20_RS15425	COG1164	Oligoendopeptidase f
A3L20_RS15430	COG1307	EDD domain protein, DegV family
A3L20_RS15470	COG2814	Major facilitator Superfamily
A3L20_RS15480	COG1664	Polymer-forming cytoskeletal
A3L20_RS15485	COG0789	Transcriptional regulator
A3L20_RS15490	COG4533	DNA binding
A3L20_RS15495	COG0477	Major facilitator Superfamily
A3L20_RS15495	COG2814	Major facilitator Superfamily
A3L20_RS15515	COG2261	transglycosylase associated protein
A3L20_RS15570	COG0436	Aminotransferase
A3L20_RS15575	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A3L20_RS15585	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A3L20_RS15600	COG1131	(ABC) transporter
A3L20_RS15645	COG0628	permease
A3L20_RS15660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A3L20_RS15665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A3L20_RS15680	COG2963	transposase activity
A3L20_RS15685	COG2801	Transposase and inactivated derivatives
A3L20_RS15705	COG2746	aminoglycoside 3-N-acetyltransferase activity
A3L20_RS15715	COG0697	spore germination
A3L20_RS15720	COG2318	DinB family
A3L20_RS15740	COG4912	Dna alkylation repair
A3L20_RS15745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3L20_RS15750	COG0346	lactoylglutathione lyase activity
A3L20_RS15755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L20_RS15785	COG0861	Integral membrane protein TerC family
A3L20_RS15790	COG1368	sulfuric ester hydrolase activity
A3L20_RS15795	COG0488	(ABC) transporter
A3L20_RS15800	COG1033	growth of symbiont in host cell
A3L20_RS15800	COG2409	Drug exporters of the RND superfamily
A3L20_RS15805	COG1309	transcriptional regulator
A3L20_RS15820	COG0287	Prephenate dehydrogenase
A3L20_RS15835	COG1605	Chorismate mutase
A3L20_RS15835	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A3L20_RS15865	COG3584	3D domain protein
A3L20_RS15865	COG1388	LysM domain
A3L20_RS15895	COG1879	ABC-type sugar transport system periplasmic component
A3L20_RS15905	COG1172	Belongs to the binding-protein-dependent transport system permease family
A3L20_RS15910	COG1129	ABC transporter
A3L20_RS15915	COG2390	Transcriptional regulator
A3L20_RS15920	COG1070	Carbohydrate kinase
A3L20_RS15955	COG2329	Antibiotic biosynthesis monooxygenase
A3L20_RS15970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A3L20_RS15990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A3L20_RS15995	COG4187	Peptidase family M20/M25/M40
A3L20_RS16000	COG1414	Transcriptional regulator
A3L20_RS16005	COG0833	amino acid
A3L20_RS16020	COG3239	Fatty acid desaturase
A3L20_RS16030	COG2720	vancomycin resistance protein
A3L20_RS16035	COG1785	Belongs to the alkaline phosphatase family
A3L20_RS16045	COG3655	Transcriptional regulator
A3L20_RS16070	COG0346	lactoylglutathione lyase activity
A3L20_RS16090	COG0714	Associated with various cellular activities
A3L20_RS16115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A3L20_RS16120	COG0753	catalase activity
A3L20_RS16150	COG5444	nuclease activity
A3L20_RS16180	COG2801	Transposase and inactivated derivatives
A3L20_RS16190	COG0778	Nitroreductase
A3L20_RS16195	COG1846	Transcriptional regulator
A3L20_RS16215	COG3831	ATPase activity
A3L20_RS16215	COG4884	unkown
A3L20_RS16235	COG2207	Transcriptional regulator
A3L20_RS16240	COG0456	acetyltransferase
A3L20_RS16250	COG2816	NAD+ diphosphatase activity
A3L20_RS16255	COG0697	spore germination
A3L20_RS16260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L20_RS16300	COG0730	response to heat
A3L20_RS16310	COG0833	amino acid
A3L20_RS16355	COG1329	Transcriptional regulator
A3L20_RS16385	COG0768	penicillin binding
A3L20_RS16415	COG1984	allophanate hydrolase subunit 2
A3L20_RS16420	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A3L20_RS16425	COG1414	Transcriptional regulator
A3L20_RS16440	COG0640	Transcriptional regulator
A3L20_RS16450	COG1960	acyl-CoA dehydrogenase activity
A3L20_RS16465	COG3314	Sporulation integral membrane protein YlbJ
A3L20_RS16485	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
A3L20_RS16495	COG2801	Transposase and inactivated derivatives
A3L20_RS16500	COG2963	transposase activity
A3L20_RS16515	COG3848	Pyruvate phosphate dikinase
A3L20_RS16515	COG0574	Belongs to the PEP-utilizing enzyme family
A3L20_RS16520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L20_RS16525	COG2801	Transposase and inactivated derivatives
A3L20_RS16545	COG5577	PFAM Coat F domain
A3L20_RS16550	COG3403	YqcI/YcgG family
A3L20_RS16555	COG1280	lysine exporter protein (LysE YggA)
A3L20_RS16560	COG1113	amino acid transport
A3L20_RS16585	COG1063	alcohol dehydrogenase
A3L20_RS16595	COG1027	Aspartate ammonia-lyase
A3L20_RS16600	COG0252	asparaginase activity
A3L20_RS16605	COG1396	sequence-specific DNA binding
A3L20_RS16625	COG5002	protein histidine kinase activity
A3L20_RS16650	COG2207	Transcriptional regulator
A3L20_RS16655	COG0322	excinuclease ABC activity
A3L20_RS16660	COG0531	amino acid
A3L20_RS16665	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A3L20_RS16675	COG0531	amino acid
A3L20_RS16680	COG0697	spore germination
A3L20_RS16685	COG0784	Response regulator, receiver
A3L20_RS16690	COG4191	Histidine kinase
A3L20_RS16700	COG1115	amino acid carrier protein
A3L20_RS16710	COG2124	cytochrome p450
A3L20_RS16725	COG0737	Belongs to the 5'-nucleotidase family
A3L20_RS16730	COG2267	carboxylic ester hydrolase activity
A3L20_RS16740	COG1335	isochorismatase
A3L20_RS16760	COG0583	DNA-binding transcription factor activity
A3L20_RS16765	COG1846	Transcriptional regulator
A3L20_RS16775	COG1476	TRANSCRIPTIONal
A3L20_RS16790	COG0598	Magnesium transport protein CorA
A3L20_RS16810	COG1073	alpha beta
A3L20_RS16830	COG0415	Belongs to the DNA photolyase family
A3L20_RS16835	COG0288	reversible hydration of carbon dioxide
A3L20_RS16845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3L20_RS16850	COG5609	conserved protein (DUF2294)
A3L20_RS16865	COG0697	spore germination
A3L20_RS16880	COG1575	Belongs to the MenA family. Type 1 subfamily
A3L20_RS16885	COG0803	Belongs to the bacterial solute-binding protein 9 family
A3L20_RS16890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A3L20_RS16895	COG1121	(ABC) transporter
A3L20_RS16920	COG0798	PFAM Bile acid sodium symporter
A3L20_RS16925	COG0640	Transcriptional regulator
A3L20_RS16945	COG0346	lactoylglutathione lyase activity
A3L20_RS16970	COG0745	RESPONSE REGULATOR receiver
A3L20_RS16975	COG3850	Histidine kinase
A3L20_RS16975	COG5002	protein histidine kinase activity
A3L20_RS17010	COG0277	FAD linked oxidase domain protein
A3L20_RS17020	COG1136	(ABC) transporter
A3L20_RS17055	COG2814	Major facilitator Superfamily
A3L20_RS17065	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A3L20_RS17085	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3L20_RS17115	COG0577	efflux transmembrane transporter activity
A3L20_RS17135	COG3850	Histidine kinase
A3L20_RS17135	COG5002	protein histidine kinase activity
A3L20_RS17145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3L20_RS17160	COG1619	proteins homologs of microcin C7 resistance protein MccF
A3L20_RS17180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A3L20_RS17200	COG0662	Cupin 2, conserved barrel domain protein
A3L20_RS17205	COG2207	Transcriptional regulator
A3L20_RS17205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L20_RS17225	COG3409	Peptidoglycan-binding domain 1 protein
A3L20_RS17225	COG5632	N-Acetylmuramoyl-L-alanine amidase
A3L20_RS17235	COG2814	Major facilitator Superfamily
A3L20_RS17275	COG5444	nuclease activity
A3L20_RS17300	COG5444	nuclease activity
A3L20_RS17315	COG5444	nuclease activity
A3L20_RS17360	COG1876	peptidase activity
A3L20_RS17365	COG2843	Capsule synthesis protein
A3L20_RS17375	COG0477	Major facilitator Superfamily
A3L20_RS17390	COG1846	Transcriptional regulator
A3L20_RS17395	COG2814	Major facilitator Superfamily
A3L20_RS17405	COG2031	fatty acid transporter
A3L20_RS17415	COG2249	NAD(P)H dehydrogenase (quinone) activity
A3L20_RS17470	COG1288	antiporter activity
A3L20_RS17475	COG2356	endonuclease I
A3L20_RS17485	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A3L20_RS17490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A3L20_RS17510	COG1733	regulation of RNA biosynthetic process
A3L20_RS17515	COG0778	Nitroreductase
A3L20_RS17545	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS17555	COG1131	(ABC) transporter
A3L20_RS17580	COG1011	Hydrolase
A3L20_RS17590	COG2365	Tyrosine phosphatase family
A3L20_RS17605	COG1051	belongs to the nudix hydrolase family
A3L20_RS17615	COG0346	lactoylglutathione lyase activity
A3L20_RS17620	COG1940	carbohydrate kinase activity
A3L20_RS17625	COG0738	Major facilitator superfamily
A3L20_RS17630	COG0110	maltose O-acetyltransferase activity
A3L20_RS17645	COG0628	permease
A3L20_RS17680	COG0500	methyltransferase
A3L20_RS17690	COG0477	Major facilitator Superfamily
A3L20_RS17720	COG1253	flavin adenine dinucleotide binding
A3L20_RS17725	COG0789	Transcriptional regulator
A3L20_RS17735	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A3L20_RS17760	COG0697	spore germination
A3L20_RS17775	COG1357	PFAM Pentapeptide repeats (8 copies)
A3L20_RS17780	COG3813	Protein conserved in bacteria
A3L20_RS17785	COG2706	6-phosphogluconolactonase activity
A3L20_RS17790	COG1070	Carbohydrate kinase
A3L20_RS17795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A3L20_RS17800	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A3L20_RS17805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A3L20_RS17810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A3L20_RS17825	COG0814	amino acid
A3L20_RS17855	COG1733	regulation of RNA biosynthetic process
A3L20_RS17860	COG2188	Transcriptional regulator
A3L20_RS17870	COG0673	inositol 2-dehydrogenase activity
A3L20_RS17895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L20_RS17920	COG0384	phenazine biosynthesis protein PhzF
A3L20_RS17930	COG0318	PFAM AMP-dependent synthetase and ligase
A3L20_RS17935	COG2249	NAD(P)H dehydrogenase (quinone) activity
A3L20_RS17940	COG1733	regulation of RNA biosynthetic process
A3L20_RS17945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3L20_RS17975	COG1191	sigma factor activity
A3L20_RS18025	COG1151	hydroxylamine reductase activity
A3L20_RS18030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L20_RS18060	COG2072	flavoprotein involved in K transport
A3L20_RS18090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L20_RS18095	COG0604	alcohol dehydrogenase
A3L20_RS18100	COG1113	amino acid transport
A3L20_RS18105	COG2814	Major facilitator Superfamily
A3L20_RS18135	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A3L20_RS18140	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A3L20_RS18150	COG1247	-acetyltransferase
A3L20_RS18155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L20_RS18160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L20_RS18165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L20_RS18170	COG3739	integral membrane protein
A3L20_RS18200	COG0583	DNA-binding transcription factor activity
A3L20_RS18220	COG1193	negative regulation of DNA recombination
A3L20_RS18235	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A3L20_RS18240	COG1164	Oligoendopeptidase f
A3L20_RS18245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3L20_RS18255	COG2271	Major facilitator Superfamily
A3L20_RS18270	COG0584	glycerophosphoryl diester phosphodiesterase
A3L20_RS18280	COG0640	Transcriptional regulator
A3L20_RS18285	COG0604	alcohol dehydrogenase
A3L20_RS18295	COG0457	Tetratricopeptide repeat
A3L20_RS18305	COG0385	Bile acid
A3L20_RS18310	COG0277	FAD linked oxidase domain protein
A3L20_RS18330	COG1252	NADH dehydrogenase
A3L20_RS18345	COG4641	Protein conserved in bacteria
A3L20_RS18355	COG2089	acid synthase
A3L20_RS18370	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
A3L20_RS18375	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A3L20_RS18380	COG1088	dTDP-glucose 4,6-dehydratase activity
A3L20_RS18390	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A3L20_RS18395	COG0463	Glycosyl transferase, family 2
A3L20_RS18400	COG0463	Glycosyl transferase, family 2
A3L20_RS18410	COG0823	Involved in the tonB-independent uptake of proteins
A3L20_RS18425	COG1131	(ABC) transporter
A3L20_RS18430	COG1132	(ABC) transporter
A3L20_RS18450	COG3397	chitin binding
A3L20_RS18460	COG0697	spore germination
A3L20_RS18480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A3L20_RS18500	COG0457	Tetratricopeptide repeat
A3L20_RS18555	COG0488	(ABC) transporter
A3L20_RS18560	COG1309	transcriptional regulator
A3L20_RS18575	COG1876	peptidase activity
A3L20_RS18600	COG3852	Histidine kinase
A3L20_RS18610	COG1285	pathogenesis
A3L20_RS18620	COG2514	catechol 2,3-dioxygenase activity
A3L20_RS18625	COG2801	Transposase and inactivated derivatives
A3L20_RS18630	COG2963	transposase activity
A3L20_RS18635	COG2720	vancomycin resistance protein
A3L20_RS18670	COG0716	FMN binding
A3L20_RS18680	COG0494	nUDIX hydrolase
A3L20_RS18700	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS18710	COG0165	Argininosuccinate lyase
A3L20_RS18725	COG4145	pantothenate transmembrane transporter activity
A3L20_RS18735	COG1012	belongs to the aldehyde dehydrogenase family
A3L20_RS18740	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS18750	COG1657	PFAM Prenyltransferase squalene oxidase
A3L20_RS18755	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A3L20_RS18760	COG2962	Rard protein
A3L20_RS18765	COG3326	Membrane
A3L20_RS18780	COG0489	protein tyrosine kinase activity
A3L20_RS18790	COG0314	molybdopterin synthase activity
A3L20_RS18795	COG0303	'Molybdopterin
A3L20_RS18800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3L20_RS18805	COG2116	formate transmembrane transporter activity
A3L20_RS18815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A3L20_RS18820	COG5609	conserved protein (DUF2294)
A3L20_RS18825	COG2427	Protein of unknown function (DUF1641)
A3L20_RS18830	COG3383	formate dehydrogenase (NAD+) activity
A3L20_RS18835	COG0697	spore germination
A3L20_RS18850	COG0531	amino acid
A3L20_RS18885	COG2226	methyltransferase
A3L20_RS18890	COG4166	transmembrane transport
A3L20_RS18900	COG4166	transmembrane transport
A3L20_RS18905	COG1301	dicarboxylic acid transport
A3L20_RS18910	COG1316	TRANSCRIPTIONal
A3L20_RS18920	COG1595	DNA-templated transcription, initiation
A3L20_RS18930	COG1131	(ABC) transporter
A3L20_RS18950	COG0673	inositol 2-dehydrogenase activity
A3L20_RS18955	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A3L20_RS18960	COG0187	DNA topoisomerase II activity
A3L20_RS18965	COG1832	CoA-binding protein
A3L20_RS18970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3L20_RS18975	COG0745	RESPONSE REGULATOR receiver
A3L20_RS18995	COG4841	protein insertion into membrane
A3L20_RS19000	COG0824	Thioesterase
A3L20_RS19025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3L20_RS19030	COG1132	(ABC) transporter
A3L20_RS19035	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A3L20_RS19065	COG2211	Major facilitator Superfamily
A3L20_RS19075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L20_RS19090	COG0183	Belongs to the thiolase family
A3L20_RS19095	COG0318	PFAM AMP-dependent synthetase and ligase
A3L20_RS19100	COG1268	BioY protein
A3L20_RS19105	COG0318	PFAM AMP-dependent synthetase and ligase
A3L20_RS19110	COG1396	sequence-specific DNA binding
A3L20_RS19150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3L20_RS19160	COG5002	protein histidine kinase activity
A3L20_RS19165	COG0400	carboxylic ester hydrolase activity
A3L20_RS19170	COG0346	lactoylglutathione lyase activity
A3L20_RS19175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3L20_RS19185	COG0069	glutamate synthase activity
A3L20_RS19190	COG1902	pentaerythritol trinitrate reductase activity
A3L20_RS19195	COG1329	Transcriptional regulator
A3L20_RS19200	COG0010	Belongs to the arginase family
A3L20_RS19250	COG4846	Membrane protein involved in cytochrome C biogenesis
A3L20_RS19255	COG0785	Cytochrome C biogenesis protein
A3L20_RS19265	COG1473	amidohydrolase
A3L20_RS19270	COG2963	transposase activity
A3L20_RS19275	COG2801	Transposase and inactivated derivatives
A3L20_RS19310	COG0583	DNA-binding transcription factor activity
A3L20_RS19320	COG1346	cytolysis
A3L20_RS19335	COG0730	response to heat
A3L20_RS19365	COG1132	(ABC) transporter
A3L20_RS19370	COG1132	(ABC) transporter
A3L20_RS19405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3L20_RS19410	COG0737	Belongs to the 5'-nucleotidase family
A3L20_RS19420	COG0737	Belongs to the 5'-nucleotidase family
A3L20_RS19430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A3L20_RS19450	COG1695	Transcriptional regulator
A3L20_RS19460	COG0739	heme binding
A3L20_RS19460	COG0741	lytic transglycosylase activity
A3L20_RS19460	COG1196	nuclear chromosome segregation
A3L20_RS19465	COG0741	lytic transglycosylase activity
A3L20_RS19495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A3L20_RS19500	COG0174	glutamine synthetase
A3L20_RS19505	COG0789	Transcriptional regulator
A3L20_RS19510	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A3L20_RS19515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A3L20_RS19520	COG2860	membrane
A3L20_RS19530	COG0464	growth
A3L20_RS19555	COG3584	3D domain protein
A3L20_RS19555	COG1388	LysM domain
A3L20_RS19560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3L20_RS19560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A3L20_RS19560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A3L20_RS19565	COG1105	Belongs to the carbohydrate kinase PfkB family
A3L20_RS19570	COG1349	DNA-binding transcription factor activity
A3L20_RS19575	COG1979	alcohol dehydrogenase
A3L20_RS19580	COG2322	membrane
A3L20_RS19595	COG1113	amino acid transport
A3L20_RS19610	COG1408	metallophosphoesterase
A3L20_RS19615	COG2116	formate transmembrane transporter activity
A3L20_RS19630	COG2217	Heavy metal translocating P-type atpase
A3L20_RS19635	COG2608	mercury ion transmembrane transporter activity
A3L20_RS19640	COG1937	Protein conserved in bacteria
A3L20_RS19660	COG2819	hydrolase of the alpha beta superfamily
A3L20_RS19665	COG1120	ATPase activity
A3L20_RS19670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L20_RS19675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L20_RS19680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L20_RS19685	COG0708	Exodeoxyribonuclease III
A3L20_RS19690	COG2169	Transcriptional regulator
A3L20_RS19695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3L20_RS19700	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A3L20_RS19710	COG2364	Membrane
A3L20_RS19725	COG2267	carboxylic ester hydrolase activity
A3L20_RS19730	COG5001	Diguanylate cyclase
A3L20_RS19730	COG3300	MHYT domain
A3L20_RS19750	COG1086	Polysaccharide biosynthesis protein
A3L20_RS19770	COG1346	cytolysis
A3L20_RS19780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L20_RS19795	COG0840	transmembrane signaling receptor activity
A3L20_RS19805	COG1404	Belongs to the peptidase S8 family
A3L20_RS19810	COG3773	Cell wall hydrolase
A3L20_RS19825	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A3L20_RS19870	COG1131	(ABC) transporter
A3L20_RS19875	COG1725	Transcriptional regulator
A3L20_RS19910	COG2801	Transposase and inactivated derivatives
A3L20_RS19915	COG0840	transmembrane signaling receptor activity
A3L20_RS19930	COG1396	sequence-specific DNA binding
A3L20_RS19965	COG4550	Control of competence regulator ComK, YlbF/YmcA
A3L20_RS19975	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L20_RS19980	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L20_RS19980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L20_RS19990	COG2359	stage V sporulation protein S
A3L20_RS19995	COG1692	metallophosphoesterase
A3L20_RS20020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A3L20_RS20025	COG1426	Protein conserved in bacteria
A3L20_RS20040	COG0300	oxidoreductase activity
A3L20_RS20045	COG0612	Peptidase, M16
A3L20_RS20050	COG0612	Peptidase, M16
A3L20_RS20055	COG1079	Belongs to the binding-protein-dependent transport system permease family
A3L20_RS20060	COG4603	Belongs to the binding-protein-dependent transport system permease family
A3L20_RS20065	COG3845	ABC transporter
A3L20_RS20070	COG1744	ABC transporter substrate-binding protein PnrA-like
A3L20_RS20075	COG2188	Transcriptional regulator
A3L20_RS20090	COG0740	serine-type endopeptidase activity
A3L20_RS20095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A3L20_RS20105	COG0527	aspartate kinase activity
A3L20_RS20110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A3L20_RS20115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A3L20_RS20120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L20_RS20125	COG1873	PFAM PRC-barrel domain
A3L20_RS20130	COG0612	Peptidase, M16
A3L20_RS20135	COG0726	polysaccharide deacetylase
A3L20_RS20150	COG0196	riboflavin kinase activity
A3L20_RS20160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A3L20_RS20165	COG1550	Protein conserved in bacteria
A3L20_RS20175	COG1358	cellular component organization or biogenesis
A3L20_RS20180	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A3L20_RS20185	COG0195	Participates in both transcription termination and antitermination
A3L20_RS20205	COG0750	zinc metalloprotease
A3L20_RS20215	COG4589	Belongs to the CDS family
A3L20_RS20260	COG4974	Belongs to the 'phage' integrase family
A3L20_RS20270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3L20_RS20275	COG0758	DNA mediated transformation
A3L20_RS20280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A3L20_RS20320	COG1837	Belongs to the UPF0109 family
A3L20_RS20330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L20_RS20340	COG0552	protein localization to endoplasmic reticulum
A3L20_RS20345	COG1196	nuclear chromosome segregation
A3L20_RS20355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3L20_RS20360	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS20365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A3L20_RS20380	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A3L20_RS20385	COG1461	Dihydroxyacetone kinase
A3L20_RS20390	COG1302	Protein conserved in bacteria
A3L20_RS20405	COG1564	THIamine pyrophosphokinase
A3L20_RS20410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A3L20_RS20420	COG0515	serine threonine protein kinase
A3L20_RS20420	COG2815	serine threonine protein kinase
A3L20_RS20425	COG0631	protein serine/threonine phosphatase activity
A3L20_RS20435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L20_RS20435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3L20_RS20450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A3L20_RS20455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A3L20_RS20475	COG1561	YicC-like family, N-terminal region
A3L20_RS20480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A3L20_RS20515	COG3069	C4-dicarboxylate transmembrane transporter activity
A3L20_RS20575	COG0564	pseudouridine synthase activity
A3L20_RS20595	COG3599	regulation of cell shape
A3L20_RS20600	COG2302	S4 RNA-binding domain
A3L20_RS20605	COG0762	integral membrane protein
A3L20_RS20615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A3L20_RS20625	COG1873	PFAM PRC-barrel domain
A3L20_RS20630	COG1191	sigma factor activity
A3L20_RS20635	COG1191	sigma factor activity
A3L20_RS20645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3L20_RS20650	COG0849	cell division
A3L20_RS20670	COG0772	Belongs to the SEDS family
A3L20_RS20690	COG0768	penicillin binding
A3L20_RS20695	COG0768	penicillin binding
A3L20_RS20715	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A3L20_RS20730	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A3L20_RS20735	COG1399	metal-binding, possibly nucleic acid-binding protein
A3L20_RS20745	COG3480	Lon protease (S16) C-terminal proteolytic domain
A3L20_RS20750	COG1752	Esterase of the alpha-beta hydrolase superfamily
A3L20_RS20755	COG3314	Sporulation integral membrane protein YlbJ
A3L20_RS20765	COG0742	ribosomal rna small subunit methyltransferase
A3L20_RS20780	COG3679	Belongs to the UPF0342 family
A3L20_RS20785	COG0406	alpha-ribazole phosphatase activity
A3L20_RS20800	COG2340	Cysteine-rich secretory protein family
A3L20_RS20815	COG3336	cytochrome c oxidase
A3L20_RS20855	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A3L20_RS20860	COG0772	Belongs to the SEDS family
A3L20_RS20870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A3L20_RS20875	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A3L20_RS20885	COG4896	Protein conserved in bacteria
A3L20_RS20900	COG1217	gtp-binding protein TYPA
A3L20_RS20910	COG0483	inositol monophosphate 1-phosphatase activity
A3L20_RS20930	COG1982	Orn Lys Arg decarboxylase major
A3L20_RS20980	COG0022	dehydrogenase e1 component
A3L20_RS20985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A3L20_RS21000	COG0561	phosphatase activity
A3L20_RS21010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A3L20_RS21015	COG0569	domain protein
A3L20_RS21035	COG0583	DNA-binding transcription factor activity
A3L20_RS21040	COG0517	IMP dehydrogenase activity
A3L20_RS21050	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
A3L20_RS21060	COG4703	Protein of unknown function (DUF1797)
A3L20_RS21075	COG2200	EAL domain
A3L20_RS21080	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS21085	COG1408	metallophosphoesterase
A3L20_RS21135	COG2814	Major facilitator Superfamily
A3L20_RS21155	COG3209	COG3209 Rhs family protein
A3L20_RS21165	COG2205	protein histidine kinase activity
A3L20_RS21175	COG0436	Aminotransferase
A3L20_RS21180	COG1609	Transcriptional regulator
A3L20_RS21185	COG3833	ABC-type maltose transport systems, permease component
A3L20_RS21190	COG1175	transmembrane transport
A3L20_RS21195	COG2182	Extracellular solute-binding protein
A3L20_RS21205	COG0366	Alpha amylase catalytic
A3L20_RS21210	COG3842	ATPase activity
A3L20_RS21250	COG0183	Belongs to the thiolase family
A3L20_RS21280	COG1695	Transcriptional regulator
A3L20_RS21285	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS21305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3L20_RS21310	COG0436	Aminotransferase
A3L20_RS21345	COG2084	Dehydrogenase
A3L20_RS21355	COG2199	diguanylate cyclase activity
A3L20_RS21360	COG0778	Nitroreductase
A3L20_RS21385	COG1263	PTS System
A3L20_RS21385	COG2190	(PTS) system
A3L20_RS21385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A3L20_RS21390	COG3711	transcriptional antiterminator
A3L20_RS21400	COG2188	Transcriptional regulator
A3L20_RS21410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A3L20_RS21435	COG1547	Domain of unknown function (DUF309)
A3L20_RS21440	COG0456	acetyltransferase
A3L20_RS21445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A3L20_RS21450	COG4086	secreted protein
A3L20_RS21455	COG0561	phosphatase activity
A3L20_RS21460	COG0697	spore germination
A3L20_RS21475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A3L20_RS21500	COG0733	neurotransmitter:sodium symporter activity
A3L20_RS21520	COG1686	Belongs to the peptidase S11 family
A3L20_RS21525	COG1725	Transcriptional regulator
A3L20_RS21530	COG1131	(ABC) transporter
A3L20_RS21555	COG1846	Transcriptional regulator
A3L20_RS21570	COG0598	Magnesium transport protein CorA
A3L20_RS21595	COG4974	Belongs to the 'phage' integrase family
A3L20_RS21605	COG0735	belongs to the Fur family
A3L20_RS21610	COG1300	Membrane
A3L20_RS21630	COG0667	Aldo Keto reductase
A3L20_RS21635	COG0656	L-ascorbic acid biosynthetic process
A3L20_RS21640	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A3L20_RS21640	COG0456	acetyltransferase
A3L20_RS21650	COG4085	toxin activity
A3L20_RS21650	COG1525	nuclease
A3L20_RS21650	COG0737	Belongs to the 5'-nucleotidase family
A3L20_RS21660	COG0596	Alpha beta hydrolase
A3L20_RS21665	COG2056	Na+-H+ antiporter family
A3L20_RS21670	COG1609	Transcriptional regulator
A3L20_RS21675	COG0456	acetyltransferase
A3L20_RS21680	COG1073	alpha beta
A3L20_RS21695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A3L20_RS21695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A3L20_RS21700	COG0307	riboflavin synthase, alpha
A3L20_RS21730	COG1073	alpha beta
A3L20_RS21730	COG2226	methyltransferase
A3L20_RS21745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A3L20_RS21755	COG1757	Na H antiporter
A3L20_RS21760	COG0737	Belongs to the 5'-nucleotidase family
A3L20_RS21770	COG1522	sequence-specific DNA binding
A3L20_RS21815	COG0300	oxidoreductase activity
A3L20_RS21820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L20_RS21825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A3L20_RS21830	COG1760	l-serine dehydratase
A3L20_RS21835	COG1760	l-serine dehydratase
A3L20_RS21860	COG1285	pathogenesis
A3L20_RS21870	COG2195	Cleaves the N-terminal amino acid of tripeptides
A3L20_RS21875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L20_RS21885	COG1376	ErfK ybiS ycfS ynhG family protein
A3L20_RS21890	COG4129	membrane
A3L20_RS21895	COG1126	abc transporter atp-binding protein
A3L20_RS21900	COG0765	amino acid transport
A3L20_RS21905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3L20_RS21925	COG2323	membrane
A3L20_RS21930	COG0772	Belongs to the SEDS family
A3L20_RS21935	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3L20_RS21940	COG0022	dehydrogenase e1 component
A3L20_RS21945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A3L20_RS21950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A3L20_RS21965	COG0280	phosphate acetyltransferase
A3L20_RS21970	COG3829	transcription factor binding
A3L20_RS21970	COG3290	protein histidine kinase activity
A3L20_RS21980	COG0584	glycerophosphoryl diester phosphodiesterase
A3L20_RS21985	COG3093	addiction module antidote protein HigA
A3L20_RS22000	COG0750	zinc metalloprotease
A3L20_RS22005	COG0497	DNA recombination
A3L20_RS22015	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A3L20_RS22025	COG0142	geranyltranstransferase activity
A3L20_RS22050	COG1302	Protein conserved in bacteria
A3L20_RS22055	COG0439	Biotin carboxylase
A3L20_RS22060	COG0511	ligase activity, forming carbon-carbon bonds
A3L20_RS22100	COG3854	ATPases associated with a variety of cellular activities
A3L20_RS22125	COG0006	proline dipeptidase activity
A3L20_RS22140	COG3872	metal-dependent enzyme
A3L20_RS22150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A3L20_RS22185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A3L20_RS22195	COG1609	Transcriptional regulator
A3L20_RS22205	COG2076	Multidrug Resistance protein
A3L20_RS22210	COG2076	Multidrug Resistance protein
A3L20_RS22250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A3L20_RS22315	COG1459	type II secretion system
A3L20_RS22320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A3L20_RS22375	COG0646	methionine synthase
A3L20_RS22375	COG1410	methionine synthase
A3L20_RS22380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A3L20_RS22380	COG0646	methionine synthase
A3L20_RS22385	COG0626	cystathionine gamma-synthase activity
A3L20_RS22390	COG0626	cystathionine gamma-synthase activity
A3L20_RS22410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L20_RS22415	COG1940	carbohydrate kinase activity
A3L20_RS22420	COG4483	Protein conserved in bacteria
A3L20_RS22425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A3L20_RS22430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A3L20_RS22435	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A3L20_RS22440	COG0704	Plays a role in the regulation of phosphate uptake
A3L20_RS22450	COG0573	inorganic phosphate transmembrane transporter activity
A3L20_RS22455	COG0573	inorganic phosphate transmembrane transporter activity
A3L20_RS22465	COG0768	penicillin binding
A3L20_RS22470	COG0477	Major facilitator Superfamily
A3L20_RS22475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A3L20_RS22485	COG5521	maltodextrose utilization protein MalA
A3L20_RS22500	COG0735	belongs to the Fur family
A3L20_RS22505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A3L20_RS22510	COG1121	(ABC) transporter
A3L20_RS22515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3L20_RS22545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A3L20_RS22550	COG2384	SAM-dependent methyltransferase
A3L20_RS22560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A3L20_RS22565	COG0358	DNA primase activity
A3L20_RS22575	COG0517	IMP dehydrogenase activity
A3L20_RS22590	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A3L20_RS22595	COG0295	cytidine deaminase activity
A3L20_RS22600	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A3L20_RS22610	COG1480	7TM receptor with intracellular HD hydrolase
A3L20_RS22615	COG1702	phosphate starvation-inducible protein PhoH
A3L20_RS22630	COG1610	YqeY-like protein
A3L20_RS22635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A3L20_RS22640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A3L20_RS22645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A3L20_RS22675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A3L20_RS22680	COG1733	regulation of RNA biosynthetic process
A3L20_RS22705	COG1466	dna polymerase III delta subunit
A3L20_RS22715	COG0658	competence protein
A3L20_RS22715	COG2333	competence protein COMEC
A3L20_RS22720	COG2131	deaminase
A3L20_RS22725	COG1555	photosystem II stabilization
A3L20_RS22725	COG1596	polysaccharide export
A3L20_RS22730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A3L20_RS22735	COG2226	methyltransferase
A3L20_RS22740	COG0799	negative regulation of ribosome biogenesis
A3L20_RS22745	COG1713	HD superfamily hydrolase involved in NAD metabolism
A3L20_RS22755	COG1534	Rna-binding protein
A3L20_RS22765	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A3L20_RS22770	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A3L20_RS22795	COG1595	DNA-templated transcription, initiation
A3L20_RS22805	COG0778	Nitroreductase
A3L20_RS22810	COG2357	RelA SpoT domain protein
A3L20_RS22820	COG1785	Belongs to the alkaline phosphatase family
A3L20_RS22830	COG2267	carboxylic ester hydrolase activity
A3L20_RS22865	COG1404	Belongs to the peptidase S8 family
A3L20_RS22870	COG3186	Phenylalanine-4-hydroxylase
A3L20_RS22880	COG2514	catechol 2,3-dioxygenase activity
A3L20_RS22885	COG2259	Doxx family
A3L20_RS22925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L20_RS22935	COG1454	alcohol dehydrogenase
A3L20_RS22935	COG1012	belongs to the aldehyde dehydrogenase family
A3L20_RS22940	COG0626	cystathionine gamma-synthase activity
A3L20_RS22945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3L20_RS22970	COG0768	penicillin binding
A3L20_RS22990	COG0826	peptidase U32
A3L20_RS22995	COG0826	peptidase U32
A3L20_RS23000	COG4122	O-methyltransferase activity
A3L20_RS23005	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A3L20_RS23020	COG4472	Bacterial protein of unknown function (DUF965)
A3L20_RS23035	COG0628	permease
A3L20_RS23055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A3L20_RS23070	COG1104	cysteine desulfurase activity
A3L20_RS23075	COG1959	2 iron, 2 sulfur cluster binding
A3L20_RS23080	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A3L20_RS23090	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A3L20_RS23120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A3L20_RS23130	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A3L20_RS23130	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A3L20_RS23135	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A3L20_RS23140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3L20_RS23140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3L20_RS23150	COG2244	polysaccharide biosynthetic process
A3L20_RS23155	COG2323	membrane
A3L20_RS23165	COG1862	Preprotein translocase
A3L20_RS23195	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A3L20_RS23225	COG0157	Belongs to the NadC ModD family
A3L20_RS23230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A3L20_RS23235	COG1104	cysteine desulfurase activity
A3L20_RS23240	COG1827	regulation of RNA biosynthetic process
A3L20_RS23245	COG2258	MOSC domain
A3L20_RS23255	COG0077	Prephenate dehydratase
A3L20_RS23260	COG0577	efflux transmembrane transporter activity
A3L20_RS23265	COG0577	efflux transmembrane transporter activity
A3L20_RS23270	COG1136	(ABC) transporter
A3L20_RS23275	COG5002	protein histidine kinase activity
A3L20_RS23280	COG0745	RESPONSE REGULATOR receiver
A3L20_RS23290	COG3290	protein histidine kinase activity
A3L20_RS23300	COG2868	ribosomal protein
A3L20_RS23310	COG1530	ribonuclease E activity
A3L20_RS23315	COG1994	Peptidase M50
A3L20_RS23320	COG0739	heme binding
A3L20_RS23325	COG2894	cell division
A3L20_RS23345	COG1077	Cell shape determining protein MreB Mrl
A3L20_RS23365	COG0285	dihydrofolate synthase activity
A3L20_RS23380	COG1388	LysM domain
A3L20_RS23390	COG0113	porphobilinogen synthase activity
A3L20_RS23395	COG1587	Uroporphyrinogen-III synthase
A3L20_RS23405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A3L20_RS23415	COG1846	Transcriptional regulator
A3L20_RS23420	COG1764	response to oxidative stress
A3L20_RS23435	COG0470	DNA polymerase III
A3L20_RS23435	COG1067	ATP-dependent peptidase activity
A3L20_RS23475	COG0622	Phosphoesterase
A3L20_RS23490	COG5401	PFAM Sporulation and spore germination
A3L20_RS23510	COG1309	transcriptional regulator
A3L20_RS23520	COG2197	response regulator
A3L20_RS23525	COG2233	PERMEase
A3L20_RS23530	COG0402	S-adenosylhomocysteine deaminase activity
A3L20_RS23535	COG1983	PspC domain protein
A3L20_RS23540	COG1396	sequence-specific DNA binding
A3L20_RS23545	COG0697	spore germination
A3L20_RS23555	COG1959	2 iron, 2 sulfur cluster binding
A3L20_RS23560	COG1668	transmembrane transport
A3L20_RS23565	COG4152	abc transporter atp-binding protein
A3L20_RS23570	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A3L20_RS23575	COG1360	Flagellar Motor Protein
A3L20_RS23580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A3L20_RS23585	COG1876	peptidase activity
A3L20_RS23590	COG0824	Thioesterase
A3L20_RS23595	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A3L20_RS23600	COG1053	succinate dehydrogenase
A3L20_RS23605	COG2009	succinate dehydrogenase
A3L20_RS23610	COG1719	4-vinyl reductase, 4VR
A3L20_RS23620	COG3118	belongs to the thioredoxin family
A3L20_RS23625	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A3L20_RS23630	COG2086	electron transfer activity
A3L20_RS23635	COG1024	Enoyl-CoA hydratase
A3L20_RS23640	COG1309	transcriptional regulator
A3L20_RS23645	COG0318	PFAM AMP-dependent synthetase and ligase
A3L20_RS23670	COG2318	DinB family
A3L20_RS23685	COG1131	(ABC) transporter
A3L20_RS23690	COG2205	protein histidine kinase activity
A3L20_RS23695	COG0745	RESPONSE REGULATOR receiver
A3L20_RS23705	COG4895	conserved protein (DUF2196)
A3L20_RS23710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A3L20_RS23720	COG4509	Sortase family
A3L20_RS23725	COG1120	ATPase activity
A3L20_RS23740	COG5386	Cell surface protein
A3L20_RS23750	COG5386	Cell surface protein
A3L20_RS23755	COG1114	Component of the transport system for branched-chain amino acids
A3L20_RS23760	COG1187	pseudouridine synthase activity
A3L20_RS23770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A3L20_RS23770	COG1796	DNA polymerase
A3L20_RS23775	COG1286	toxin biosynthetic process
A3L20_RS23815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A3L20_RS23825	COG1418	mRNA catabolic process
A3L20_RS23840	COG2814	Major facilitator Superfamily
A3L20_RS23845	COG1566	PFAM secretion protein HlyD family protein
A3L20_RS23850	COG1309	transcriptional regulator
A3L20_RS23855	COG1363	Peptidase, m42
A3L20_RS23880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A3L20_RS23900	COG2801	Transposase and inactivated derivatives
A3L20_RS23905	COG1484	DNA-dependent DNA replication
A3L20_RS23910	COG3611	Membrane attachment protein
A3L20_RS23920	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A3L20_RS23925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A3L20_RS23930	COG0237	dephospho-CoA kinase activity
A3L20_RS23935	COG1971	Probably functions as a manganese efflux pump
A3L20_RS23945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A3L20_RS23945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A3L20_RS23950	COG5002	protein histidine kinase activity
A3L20_RS23955	COG0745	RESPONSE REGULATOR receiver
A3L20_RS23975	COG0538	isocitrate dehydrogenase activity
A3L20_RS23980	COG0372	Belongs to the citrate synthase family
A3L20_RS23990	COG0628	permease
A3L20_RS23995	COG3030	protein affecting phage T7 exclusion by the F plasmid
A3L20_RS24020	COG1725	Transcriptional regulator
A3L20_RS24025	COG0281	malic enzyme
A3L20_RS24030	COG0587	DNA-directed DNA polymerase activity
A3L20_RS24045	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A3L20_RS24060	COG4109	DRTGG domain
A3L20_RS24075	COG0006	proline dipeptidase activity
A3L20_RS24110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L20_RS24115	COG0662	Cupin 2, conserved barrel domain protein
A3L20_RS24130	COG1028	Short-chain dehydrogenase reductase Sdr
A3L20_RS24135	COG0589	response to stress
A3L20_RS24175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3L20_RS24200	COG0827	DNA restriction-modification system
A3L20_RS24205	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A3L20_RS24210	COG3874	Sporulation protein YtfJ
A3L20_RS24225	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A3L20_RS24235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A3L20_RS24250	COG1104	cysteine desulfurase activity
A3L20_RS24260	COG0583	DNA-binding transcription factor activity
A3L20_RS24265	COG0697	spore germination
A3L20_RS24270	COG1309	transcriptional regulator
A3L20_RS24275	COG1956	GAF domain-containing protein
A3L20_RS24280	COG0626	cystathionine gamma-synthase activity
A3L20_RS24315	COG0110	maltose O-acetyltransferase activity
A3L20_RS24320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A3L20_RS24325	COG0454	-acetyltransferase
A3L20_RS24330	COG0517	IMP dehydrogenase activity
A3L20_RS24335	COG0123	including yeast histone deacetylase and acetoin utilization protein
A3L20_RS24350	COG0745	RESPONSE REGULATOR receiver
A3L20_RS24355	COG5002	protein histidine kinase activity
A3L20_RS24360	COG0666	response to abiotic stimulus
A3L20_RS24395	COG1609	Transcriptional regulator
A3L20_RS24400	COG1605	Chorismate mutase
A3L20_RS24400	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A3L20_RS24405	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A3L20_RS24405	COG1605	Chorismate mutase
A3L20_RS24410	COG1605	Chorismate mutase
A3L20_RS24410	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A3L20_RS24415	COG4851	CamS sex pheromone cAM373 precursor
A3L20_RS24420	COG3118	belongs to the thioredoxin family
A3L20_RS24445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L20_RS24450	COG0697	spore germination
A3L20_RS24455	COG0789	Transcriptional regulator
A3L20_RS24470	COG1674	ftsk spoiiie
A3L20_RS24485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L20_RS24495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3L20_RS24500	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
A3L20_RS24505	COG1363	Peptidase, m42
A3L20_RS24515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L20_RS24530	COG0510	thiamine kinase activity
A3L20_RS24535	COG1523	belongs to the glycosyl hydrolase 13 family
A3L20_RS24545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L20_RS24550	COG1349	DNA-binding transcription factor activity
A3L20_RS24555	COG1187	pseudouridine synthase activity
A3L20_RS24580	COG3832	glyoxalase III activity
A3L20_RS24600	COG1329	Transcriptional regulator
A3L20_RS24625	COG0314	molybdopterin synthase activity
A3L20_RS24630	COG1763	Mo-molybdopterin cofactor biosynthetic process
A3L20_RS24635	COG0303	'Molybdopterin
A3L20_RS24645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3L20_RS24650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L20_RS24670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A3L20_RS24680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A3L20_RS24720	COG2814	Major facilitator Superfamily
A3L20_RS24725	COG0475	glutathione-regulated potassium exporter activity
A3L20_RS24730	COG0490	domain, Protein
A3L20_RS24735	COG0582	viral genome integration into host DNA
A3L20_RS24745	COG1136	(ABC) transporter
A3L20_RS24765	COG1242	4 iron, 4 sulfur cluster binding
A3L20_RS24770	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A3L20_RS24775	COG1794	racemase activity, acting on amino acids and derivatives
A3L20_RS24790	COG2267	carboxylic ester hydrolase activity
A3L20_RS24795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A3L20_RS24800	COG0671	phosphoesterase, PA-phosphatase related
A3L20_RS24805	COG0438	transferase activity, transferring glycosyl groups
A3L20_RS24895	COG5002	protein histidine kinase activity
A3L20_RS24900	COG3852	Histidine kinase
A3L20_RS24905	COG0753	catalase activity
A3L20_RS24910	COG2267	carboxylic ester hydrolase activity
A3L20_RS24915	COG1368	sulfuric ester hydrolase activity
A3L20_RS24930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A3L20_RS24935	COG1116	anion transmembrane transporter activity
A3L20_RS24940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A3L20_RS24965	COG0494	nUDIX hydrolase
A3L20_RS25000	COG2076	Multidrug Resistance protein
A3L20_RS25005	COG2076	Multidrug Resistance protein
A3L20_RS25010	COG0789	Transcriptional regulator
A3L20_RS25015	COG1854	S-ribosylhomocysteine lyase activity
A3L20_RS25025	COG0288	reversible hydration of carbon dioxide
A3L20_RS25030	COG1271	oxidase subunit
A3L20_RS25035	COG1294	oxidase, subunit
A3L20_RS25050	COG2963	transposase activity
A3L20_RS25055	COG2801	Transposase and inactivated derivatives
A3L20_RS25070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3L20_RS25095	COG1842	Phage shock protein A
A3L20_RS25120	COG3859	Proton-coupled thiamine transporter YuaJ
A3L20_RS25125	COG5002	protein histidine kinase activity
A3L20_RS25130	COG0745	RESPONSE REGULATOR receiver
A3L20_RS25155	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A3L20_RS25160	COG1597	lipid kinase activity
A3L20_RS25205	COG0586	Pfam SNARE associated Golgi protein
A3L20_RS25215	COG0577	efflux transmembrane transporter activity
A3L20_RS25220	COG1136	(ABC) transporter
A3L20_RS25225	COG3708	Transcriptional regulator
A3L20_RS25225	COG2207	Transcriptional regulator
A3L20_RS25280	COG1131	(ABC) transporter
A3L20_RS25285	COG5658	integral membrane protein
A3L20_RS25290	COG0640	Transcriptional regulator
A3L20_RS25300	COG0745	RESPONSE REGULATOR receiver
A3L20_RS25305	COG2205	protein histidine kinase activity
A3L20_RS25310	COG0577	efflux transmembrane transporter activity
A3L20_RS25315	COG0577	efflux transmembrane transporter activity
A3L20_RS25320	COG1136	(ABC) transporter
A3L20_RS25325	COG0577	efflux transmembrane transporter activity
A3L20_RS25340	COG2188	Transcriptional regulator
A3L20_RS25360	COG3964	amidohydrolase
A3L20_RS25380	COG4948	Mandelate Racemase Muconate Lactonizing
A3L20_RS25390	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A3L20_RS25395	COG0596	Alpha beta hydrolase
A3L20_RS25405	COG1169	isochorismate synthase
A3L20_RS25410	COG1575	Belongs to the MenA family. Type 1 subfamily
A3L20_RS25415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A3L20_RS25420	COG1278	Cold shock
A3L20_RS25445	COG0058	SHG alpha-glucan phosphorylase activity
A3L20_RS25455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A3L20_RS25460	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A3L20_RS25480	COG1309	transcriptional regulator
A3L20_RS25615	COG1285	pathogenesis
A3L20_RS25620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A3L20_RS25635	COG2155	Conserved Protein
A3L20_RS25640	COG1098	S1 RNA binding domain
A3L20_RS25645	COG0436	Aminotransferase
A3L20_RS25650	COG1522	sequence-specific DNA binding
A3L20_RS25655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L20_RS25660	COG2267	carboxylic ester hydrolase activity
A3L20_RS25670	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A3L20_RS25690	COG5018	Exonuclease
A3L20_RS25695	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A3L20_RS25715	COG2050	protein possibly involved in aromatic compounds catabolism
A3L20_RS25725	COG1268	BioY protein
A3L20_RS25730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A3L20_RS25735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L20_RS25750	COG3584	3D domain protein
A3L20_RS25765	COG1252	NADH dehydrogenase
A3L20_RS25780	COG3708	Transcriptional regulator
A3L20_RS25795	COG1683	Conserved Protein
A3L20_RS25845	COG3409	Peptidoglycan-binding domain 1 protein
A3L20_RS25845	COG5632	N-Acetylmuramoyl-L-alanine amidase
A3L20_RS25845	COG1388	LysM domain
A3L20_RS25850	COG4824	toxin secretion phage lysis holin
A3L20_RS25985	COG1191	sigma factor activity
A3L20_RS26010	COG3645	SOS response
A3L20_RS26010	COG3646	Phage regulatory protein
A3L20_RS26030	COG1396	sequence-specific DNA binding
A3L20_RS26075	COG0316	Belongs to the HesB IscA family
A3L20_RS26090	COG1252	NADH dehydrogenase
A3L20_RS26100	COG2274	protein secretion by the type I secretion system
A3L20_RS26105	COG0390	transport system, permease component
A3L20_RS26110	COG2824	Alkylphosphonate utilization operon protein PhnA
A3L20_RS26135	COG4837	Protein of unknown function (DUF1462)
A3L20_RS26140	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A3L20_RS26150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A3L20_RS26155	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A3L20_RS26175	COG1358	cellular component organization or biogenesis
A3L20_RS26185	COG2249	NAD(P)H dehydrogenase (quinone) activity
A3L20_RS26190	COG0647	UMP catabolic process
A3L20_RS26200	COG2445	Protein of unknown function DUF86
A3L20_RS26205	COG1494	fructose-1,6-bisphosphatase
A3L20_RS26220	COG4470	Protein conserved in bacteria
A3L20_RS26230	COG0789	Transcriptional regulator
A3L20_RS26235	COG4377	Putative membrane peptidase family (DUF2324)
A3L20_RS26260	COG0739	heme binding
A3L20_RS26270	COG3377	Domain of unknown function (DUF1805)
A3L20_RS26275	COG0737	Belongs to the 5'-nucleotidase family
A3L20_RS26280	COG0719	Fe-S assembly protein
A3L20_RS26285	COG0822	iron-sulfur transferase activity
A3L20_RS26290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3L20_RS26295	COG0719	Fe-S assembly protein
A3L20_RS26300	COG0396	ATPase activity
A3L20_RS26305	COG1464	Belongs to the NlpA lipoprotein family
A3L20_RS26310	COG1464	Belongs to the NlpA lipoprotein family
A3L20_RS26315	COG2011	ABC-type metal ion transport system permease component
A3L20_RS26330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3L20_RS26335	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A3L20_RS26345	COG1393	Belongs to the ArsC family
A3L20_RS26365	COG0039	L-malate dehydrogenase activity
A3L20_RS26380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L20_RS26385	COG1960	acyl-CoA dehydrogenase activity
A3L20_RS26390	COG0183	Belongs to the thiolase family
A3L20_RS26395	COG1250	3-hydroxyacyl-CoA dehydrogenase
A3L20_RS26395	COG1024	Enoyl-CoA hydratase
A3L20_RS26405	COG1686	Belongs to the peptidase S11 family
A3L20_RS26420	COG0011	TIGRFAM Protein of
A3L20_RS26425	COG0840	transmembrane signaling receptor activity
A3L20_RS26440	COG2814	Major facilitator Superfamily
A3L20_RS26445	COG0531	amino acid
A3L20_RS26475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A3L20_RS26510	COG0586	Pfam SNARE associated Golgi protein
A3L20_RS26520	COG1376	ErfK ybiS ycfS ynhG family protein
A3L20_RS26525	COG0745	RESPONSE REGULATOR receiver
A3L20_RS26530	COG5002	protein histidine kinase activity
A3L20_RS26565	COG1132	(ABC) transporter
A3L20_RS26570	COG1131	(ABC) transporter
A3L20_RS26590	COG0840	transmembrane signaling receptor activity
A3L20_RS26595	COG2151	metal-sulfur cluster biosynthetic enzyme
A3L20_RS26600	COG3227	Zinc metalloprotease (Elastase)
A3L20_RS26620	COG0586	Pfam SNARE associated Golgi protein
A3L20_RS26625	COG0475	glutathione-regulated potassium exporter activity
A3L20_RS26630	COG0490	domain, Protein
A3L20_RS26635	COG1115	amino acid carrier protein
A3L20_RS26640	COG0783	Belongs to the Dps family
A3L20_RS26660	COG1611	Belongs to the LOG family
A3L20_RS26675	COG2311	Membrane
A3L20_RS26680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A3L20_RS26685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A3L20_RS26690	COG1115	amino acid carrier protein
A3L20_RS26695	COG1115	amino acid carrier protein
A3L20_RS26700	COG2910	NAD(P)H-binding
A3L20_RS26715	COG0656	L-ascorbic acid biosynthetic process
A3L20_RS26720	COG2814	Major facilitator Superfamily
A3L20_RS26725	COG1733	regulation of RNA biosynthetic process
A3L20_RS26735	COG1252	NADH dehydrogenase
A3L20_RS26755	COG3290	protein histidine kinase activity
A3L20_RS26755	COG0840	transmembrane signaling receptor activity
A3L20_RS26790	COG0488	(ABC) transporter
A3L20_RS26795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L20_RS26815	COG1335	isochorismatase
A3L20_RS26820	COG1522	sequence-specific DNA binding
A3L20_RS26830	COG1522	sequence-specific DNA binding
A3L20_RS26835	COG0288	reversible hydration of carbon dioxide
A3L20_RS26840	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
A3L20_RS26845	COG2233	PERMEase
A3L20_RS26895	COG0557	exoribonuclease II activity
A3L20_RS26910	COG1674	ftsk spoiiie
A3L20_RS26925	COG1388	LysM domain
A3L20_RS26925	COG5632	N-Acetylmuramoyl-L-alanine amidase
A3L20_RS26925	COG3409	Peptidoglycan-binding domain 1 protein
A3L20_RS26930	COG4824	toxin secretion phage lysis holin
A3L20_RS26955	COG3344	reverse transcriptase
A3L20_RS27000	COG0740	serine-type endopeptidase activity
A3L20_RS27010	COG3547	Transposase (IS116 IS110 IS902 family)
A3L20_RS27015	COG1802	Transcriptional regulator
A3L20_RS27015	COG4626	Terminase
A3L20_RS27065	COG0582	viral genome integration into host DNA
A3L20_RS27145	COG1396	sequence-specific DNA binding
A3L20_RS27160	COG0582	viral genome integration into host DNA
A3L20_RS27165	COG1647	Serine aminopeptidase, S33
A3L20_RS27170	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A3L20_RS27175	COG1346	cytolysis
A3L20_RS27210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A3L20_RS27225	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A3L20_RS27295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A3L20_RS27310	COG2323	membrane
A3L20_RS27320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A3L20_RS27330	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A3L20_RS27340	COG1051	belongs to the nudix hydrolase family
A3L20_RS27350	COG0492	ferredoxin-NADP+ reductase activity
A3L20_RS27355	COG0457	Tetratricopeptide repeat
A3L20_RS27360	COG0110	maltose O-acetyltransferase activity
A3L20_RS27380	COG1950	PFAM Membrane protein of
A3L20_RS27390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A3L20_RS27395	COG0556	nucleotide-excision repair
A3L20_RS27410	COG0789	Transcriptional regulator
A3L20_RS27430	COG0583	DNA-binding transcription factor activity
A3L20_RS27440	COG0655	NAD(P)H dehydrogenase (quinone) activity
A3L20_RS27450	COG1132	(ABC) transporter
A3L20_RS27455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3L20_RS27460	COG0793	Belongs to the peptidase S41A family
A3L20_RS27460	COG3409	Peptidoglycan-binding domain 1 protein
A3L20_RS27465	COG2177	Part of the ABC transporter FtsEX involved in
A3L20_RS27470	COG2884	Cell division ATP-binding protein ftsE
A3L20_RS27480	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A3L20_RS27495	COG1131	(ABC) transporter
A3L20_RS27525	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A3L20_RS27530	COG1278	Cold shock
A3L20_RS27535	COG1040	competence protein
A3L20_RS27540	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A3L20_RS27560	COG5632	N-Acetylmuramoyl-L-alanine amidase
A3L20_RS27735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A3L20_RS27740	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A3L20_RS27745	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A3L20_RS27750	COG0791	NLP P60 protein
A3L20_RS27750	COG1388	LysM domain
A3L20_RS27755	COG1733	regulation of RNA biosynthetic process
A3L20_RS27760	COG1307	EDD domain protein, DegV family
A3L20_RS27765	COG1739	Uncharacterized protein family UPF0029
A3L20_RS27770	COG1316	TRANSCRIPTIONal
A3L20_RS27775	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A3L20_RS27780	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A3L20_RS27785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A3L20_RS27795	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A3L20_RS27795	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A3L20_RS27815	COG1486	melibiose metabolic process
A3L20_RS27820	COG1447	Phosphotransferase system cellobiose-specific component IIA
A3L20_RS27825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3L20_RS27835	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A3L20_RS27845	COG1447	Phosphotransferase system cellobiose-specific component IIA
A3L20_RS27855	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A3L20_RS27860	COG1301	dicarboxylic acid transport
A3L20_RS27875	COG1511	domain protein
A3L20_RS27880	COG0583	DNA-binding transcription factor activity
A3L20_RS27895	COG1271	oxidase subunit
A3L20_RS27900	COG1294	oxidase, subunit
A3L20_RS27905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A3L20_RS27915	COG1620	l-lactate permease
A3L20_RS27925	COG2389	metal-binding protein
A3L20_RS27935	COG1368	sulfuric ester hydrolase activity
A3L20_RS27940	COG2801	Transposase and inactivated derivatives
A3L20_RS27955	COG0791	NLP P60 protein
A3L20_RS27955	COG1388	LysM domain
A3L20_RS27960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A3L20_RS27970	COG1215	transferase activity, transferring glycosyl groups
A3L20_RS27980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A3L20_RS27985	COG3584	3D domain protein
A3L20_RS27985	COG1388	LysM domain
A3L20_RS28010	COG4715	Zinc finger, swim domain protein
A3L20_RS28015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A3L20_RS28025	COG3547	Transposase (IS116 IS110 IS902 family)
A3L20_RS28060	COG0577	efflux transmembrane transporter activity
A3L20_RS28065	COG1136	(ABC) transporter
A3L20_RS28090	COG5002	protein histidine kinase activity
A3L20_RS28095	COG0745	RESPONSE REGULATOR receiver
A3L20_RS28105	COG1316	TRANSCRIPTIONal
A3L20_RS28110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A3L20_RS28115	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A3L20_RS28125	COG1215	transferase activity, transferring glycosyl groups
A3L20_RS28150	COG1215	transferase activity, transferring glycosyl groups
A3L20_RS28155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A3L20_RS28160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A3L20_RS28165	COG4464	protein tyrosine phosphatase activity
A3L20_RS28170	COG0489	protein tyrosine kinase activity
A3L20_RS28175	COG3944	biosynthesis protein
A3L20_RS28180	COG2963	transposase activity
A3L20_RS28185	COG2801	Transposase and inactivated derivatives
A3L20_RS28190	COG0489	protein tyrosine kinase activity
A3L20_RS28205	COG1609	Transcriptional regulator
A3L20_RS28215	COG0739	heme binding
A3L20_RS28230	COG3279	Response regulator of the LytR AlgR family
A3L20_RS28235	COG2385	sporulation resulting in formation of a cellular spore
A3L20_RS28250	COG4836	Membrane
A3L20_RS28255	COG1007	ATP synthesis coupled electron transport
A3L20_RS28260	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L20_RS28265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3L20_RS28275	COG0839	Belongs to the complex I subunit 6 family
A3L20_RS28295	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L20_RS28310	COG3300	MHYT domain
A3L20_RS28310	COG5001	Diguanylate cyclase
A3L20_RS28360	COG0356	it plays a direct role in the translocation of protons across the membrane
A3L20_RS28390	COG0698	ribose 5-phosphate isomerase
A3L20_RS28400	COG2190	(PTS) system
A3L20_RS28405	COG2259	Doxx family
A3L20_RS28410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A3L20_RS28425	COG0009	L-threonylcarbamoyladenylate synthase
A3L20_RS28460	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A3L20_RS28465	COG1494	fructose-1,6-bisphosphatase
A3L20_RS28485	COG4821	SIS domain
A3L20_RS28505	COG1960	acyl-CoA dehydrogenase activity
A3L20_RS28510	COG1960	acyl-CoA dehydrogenase activity
A3L20_RS28515	COG1250	3-hydroxyacyl-CoA dehydrogenase
A3L20_RS28520	COG0183	Belongs to the thiolase family
A3L20_RS28525	COG2181	nitrate reductase activity
A3L20_RS28525	COG0247	lactate metabolic process
A3L20_RS28530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A3L20_RS28540	COG3300	MHYT domain
A3L20_RS28540	COG5001	Diguanylate cyclase
A3L20_RS28555	COG3227	Zinc metalloprotease (Elastase)
A3L20_RS28560	COG2197	response regulator
A3L20_RS28565	COG4585	Histidine kinase
A3L20_RS28570	COG0842	Transport permease protein
A3L20_RS28575	COG1131	(ABC) transporter
A3L20_RS28580	COG0024	Methionine aminopeptidase
A3L20_RS28590	COG2234	aminopeptidase activity
A3L20_RS28610	COG1595	DNA-templated transcription, initiation
A3L20_RS28620	COG4506	Protein conserved in bacteria
A3L20_RS28625	COG1619	proteins homologs of microcin C7 resistance protein MccF
A3L20_RS28650	COG2814	Major facilitator Superfamily
A3L20_RS28655	COG0789	Transcriptional regulator
A3L20_RS28660	COG0584	glycerophosphoryl diester phosphodiesterase
A3L20_RS28665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A3L20_RS28675	COG1994	Peptidase M50
A3L20_RS28685	COG1078	dGTPase activity
A3L20_RS28690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L20_RS28695	COG1120	ATPase activity
A3L20_RS28700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L20_RS28705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L20_RS28725	COG0280	phosphate acetyltransferase
A3L20_RS28740	COG3773	Cell wall hydrolase
A3L20_RS28750	COG2363	Small membrane protein
A3L20_RS28760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A3L20_RS28765	COG2233	PERMEase
A3L20_RS28770	COG0561	phosphatase activity
A3L20_RS28775	COG2814	Major facilitator Superfamily
A3L20_RS28785	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A3L20_RS28790	COG1131	(ABC) transporter
A3L20_RS28795	COG2755	lipolytic protein G-D-S-L family
A3L20_RS28800	COG1609	Transcriptional regulator
A3L20_RS28810	COG0460	homoserine dehydrogenase
A3L20_RS28820	COG2873	o-acetylhomoserine
A3L20_RS28825	COG1011	Hydrolase
A3L20_RS28830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3L20_RS28840	COG2197	response regulator
A3L20_RS28845	COG4585	Histidine kinase
A3L20_RS28845	COG2203	Gaf domain
A3L20_RS28850	COG0351	phosphomethylpyrimidine kinase
A3L20_RS28855	COG3706	GGDEF domain
A3L20_RS28860	COG2879	small protein
A3L20_RS28865	COG1966	Carbon starvation protein
A3L20_RS28870	COG3279	Response regulator of the LytR AlgR family
A3L20_RS28875	COG0477	Major facilitator Superfamily
A3L20_RS28885	COG0438	transferase activity, transferring glycosyl groups
A3L20_RS28900	COG0840	transmembrane signaling receptor activity
A3L20_RS28910	COG1607	acyl-coa hydrolase
A3L20_RS28915	COG1216	Glycosyl transferase, family 2
A3L20_RS28930	COG1216	Glycosyl transferase, family 2
A3L20_RS28945	COG0463	Glycosyl transferase, family 2
A3L20_RS28955	COG1309	transcriptional regulator
A3L20_RS28960	COG0488	(ABC) transporter
A3L20_RS28965	COG1309	transcriptional regulator
A3L20_RS28970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A3L20_RS28975	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3L20_RS28975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3L20_RS28980	COG0628	permease
A3L20_RS29000	COG3275	phosphorelay sensor kinase activity
A3L20_RS29005	COG2814	Major facilitator Superfamily
A3L20_RS29010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A3L20_RS29015	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
A3L20_RS29040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A3L20_RS29045	COG1272	protein, Hemolysin III
A3L20_RS29065	COG1164	Oligoendopeptidase f
A3L20_RS29080	COG5002	protein histidine kinase activity
A3L20_RS29095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3L20_RS29100	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A3L20_RS29105	COG4853	Protein conserved in bacteria
A3L20_RS29115	COG5002	protein histidine kinase activity
A3L20_RS29120	COG0745	RESPONSE REGULATOR receiver
A3L20_RS29150	COG0305	Participates in initiation and elongation during chromosome replication
A3L20_RS29160	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A3L20_RS29165	COG4241	membrane
A3L20_RS29175	COG0629	single-stranded DNA binding
A3L20_RS29185	COG0012	GTP binding
A3L20_RS29190	COG4481	Protein conserved in bacteria
A3L20_RS29195	COG0668	transmembrane transport
A3L20_RS29205	COG1475	DNA binding
A3L20_RS29210	COG1192	Involved in chromosome partitioning
A3L20_RS29235	COG1847	R3H domain protein
A3L20_RS29250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A3L20_RS29415	COG0187	DNA topoisomerase II activity
A3L20_RS29650	COG0592	DNA-directed DNA polymerase activity
A3L20_RS29660	COG0592	DNA-directed DNA polymerase activity
A3L20_RS29675	COG0187	DNA topoisomerase II activity
A3L20_RS29855	COG1982	Orn Lys Arg decarboxylase major
A3L20_RS29885	COG1774	PSP1 C-terminal conserved region
A3L20_RS30400	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A3L20_RS30690	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A3L20_RS30760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A3L20_RS30800	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A3L20_RS30810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A3L20_RS30860	COG3956	TIGRFAM MazG family protein
A3L20_RS30890	COG2208	phosphoserine phosphatase activity
A3L20_RS30895	COG2208	phosphoserine phosphatase activity
A3L20_RS30915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L20_RS31020	COG0542	response to heat
A3L20_RS31025	COG0542	response to heat
A3L20_RS31150	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L20_RS31380	COG0592	DNA-directed DNA polymerase activity
A3L20_RS31400	COG0187	DNA topoisomerase II activity
A3L20_RS31620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A3L20_RS32040	COG0725	ABC transporter, periplasmic molybdate-binding protein
A3L20_RS32120	COG0561	phosphatase activity
A3L20_RS32270	COG2252	PERMEase
A3L20_RS32545	COG1335	isochorismatase
A3L20_RS32570	COG0003	Pfam Anion-transporting ATPase