locus-tag	class	description
HBA75_RS00010	COG0592	DNA-directed DNA polymerase activity
HBA75_RS00015	COG2501	S4 domain
HBA75_RS00025	COG0187	DNA topoisomerase II activity
HBA75_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBA75_RS00145	COG0516	GMP reductase activity
HBA75_RS00145	COG0517	IMP dehydrogenase activity
HBA75_RS00150	COG1686	Belongs to the peptidase S11 family
HBA75_RS00180	COG1428	Deoxynucleoside kinase
HBA75_RS00185	COG1428	Deoxynucleoside kinase
HBA75_RS00190	COG1335	isochorismatase
HBA75_RS00195	COG0590	tRNA wobble adenosine to inosine editing
HBA75_RS00205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBA75_RS00260	COG1982	Orn Lys Arg decarboxylase major
HBA75_RS00270	COG0470	DNA polymerase III
HBA75_RS00275	COG1774	PSP1 C-terminal conserved region
HBA75_RS00285	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HBA75_RS00305	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HBA75_RS00310	COG2002	toxin-antitoxin pair type II binding
HBA75_RS00320	COG0084	hydrolase, TatD family'
HBA75_RS00340	COG4466	Protein conserved in bacteria
HBA75_RS00355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HBA75_RS00360	COG0251	oxidation-reduction process
HBA75_RS00390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HBA75_RS00395	COG2002	toxin-antitoxin pair type II binding
HBA75_RS00400	COG2244	polysaccharide biosynthetic process
HBA75_RS00405	COG3956	TIGRFAM MazG family protein
HBA75_RS00410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HBA75_RS00430	COG1098	S1 RNA binding domain
HBA75_RS00445	COG2208	phosphoserine phosphatase activity
HBA75_RS00460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBA75_RS00475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HBA75_RS00480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HBA75_RS00485	COG0512	Glutamine amidotransferase of anthranilate synthase
HBA75_RS00490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBA75_RS00495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HBA75_RS00500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HBA75_RS00505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HBA75_RS00510	COG1396	sequence-specific DNA binding
HBA75_RS00515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBA75_RS00605	COG3880	PFAM UvrB UvrC protein
HBA75_RS00615	COG0542	response to heat
HBA75_RS00620	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HBA75_RS00630	COG4956	integral membrane protein (PIN domain superfamily)
HBA75_RS00650	COG1045	serine acetyltransferase
HBA75_RS00665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBA75_RS00670	COG3688	RNA-binding protein containing a PIN domain
HBA75_RS00685	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HBA75_RS00690	COG0250	Participates in transcription elongation, termination and antitermination
HBA75_RS00695	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HBA75_RS00715	COG2813	Specifically methylates the guanine in position
HBA75_RS00730	COG1358	cellular component organization or biogenesis
HBA75_RS00735	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HBA75_RS00800	COG0255	Belongs to the universal ribosomal protein uL29 family
HBA75_RS00860	COG0201	protein transport
HBA75_RS00870	COG0024	Methionine aminopeptidase
HBA75_RS00880	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HBA75_RS00915	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBA75_RS00940	COG0860	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS00945	COG0489	protein tyrosine kinase activity
HBA75_RS00955	COG2194	sulfuric ester hydrolase activity
HBA75_RS00960	COG0726	polysaccharide deacetylase
HBA75_RS01030	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HBA75_RS01035	COG4856	YbbR-like protein
HBA75_RS01075	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS01080	COG2011	ABC-type metal ion transport system permease component
HBA75_RS01085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBA75_RS01090	COG1464	Belongs to the NlpA lipoprotein family
HBA75_RS01095	COG0604	alcohol dehydrogenase
HBA75_RS01105	COG0277	FAD linked oxidase domain protein
HBA75_RS01110	COG2271	Major facilitator Superfamily
HBA75_RS01120	COG2814	Major facilitator Superfamily
HBA75_RS01135	COG0601	transmembrane transport
HBA75_RS01145	COG0444	Belongs to the ABC transporter superfamily
HBA75_RS01150	COG4608	Belongs to the ABC transporter superfamily
HBA75_RS01160	COG4166	transmembrane transport
HBA75_RS01170	COG2207	Transcriptional regulator
HBA75_RS01185	COG4166	transmembrane transport
HBA75_RS01190	COG4166	transmembrane transport
HBA75_RS01195	COG0656	L-ascorbic acid biosynthetic process
HBA75_RS01210	COG4149	molybdate abc transporter
HBA75_RS01215	COG0725	ABC transporter, periplasmic molybdate-binding protein
HBA75_RS01225	COG1910	domain protein
HBA75_RS01240	COG0697	spore germination
HBA75_RS01255	COG0204	Acyl-transferase
HBA75_RS01265	COG1609	Transcriptional regulator
HBA75_RS01275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_RS01290	COG5298	Protein conserved in bacteria
HBA75_RS01315	COG0488	(ABC) transporter
HBA75_RS01325	COG0747	negative chemotaxis
HBA75_RS01355	COG0444	Belongs to the ABC transporter superfamily
HBA75_RS01360	COG4608	Belongs to the ABC transporter superfamily
HBA75_RS01365	COG0561	phosphatase activity
HBA75_RS01395	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HBA75_RS01400	COG0179	Fumarylacetoacetate (FAA) hydrolase
HBA75_RS01410	COG0531	amino acid
HBA75_RS01415	COG2814	Major facilitator Superfamily
HBA75_RS01425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HBA75_RS01435	COG4294	response to UV
HBA75_RS01440	COG0705	Rhomboid family
HBA75_RS01450	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HBA75_RS01455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBA75_RS01460	COG0864	Transcriptional regulator
HBA75_RS01465	COG2337	Toxic component of a toxin-antitoxin (TA) module
HBA75_RS01470	COG2183	response to ionizing radiation
HBA75_RS01580	COG0802	atpase or kinase
HBA75_RS01585	COG1214	PFAM Peptidase M22, glycoprotease
HBA75_RS01590	COG0456	acetyltransferase
HBA75_RS01600	COG0488	(ABC) transporter
HBA75_RS01615	COG1266	CAAX protease self-immunity
HBA75_RS01635	COG2252	PERMEase
HBA75_RS01645	COG5002	protein histidine kinase activity
HBA75_RS01670	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HBA75_RS01710	COG2205	protein histidine kinase activity
HBA75_RS01715	COG0745	RESPONSE REGULATOR receiver
HBA75_RS01745	COG2226	methyltransferase
HBA75_RS01795	COG1215	transferase activity, transferring glycosyl groups
HBA75_RS01815	COG0697	spore germination
HBA75_RS01840	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HBA75_RS01845	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HBA75_RS01850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HBA75_RS01860	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBA75_RS01875	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HBA75_RS01885	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HBA75_RS01895	COG0151	Belongs to the GarS family
HBA75_RS01920	COG0210	DNA helicase
HBA75_RS01930	COG4851	CamS sex pheromone cAM373 precursor
HBA75_RS01945	COG1335	isochorismatase
HBA75_RS01955	COG2011	ABC-type metal ion transport system permease component
HBA75_RS01960	COG1464	Belongs to the NlpA lipoprotein family
HBA75_RS01975	COG0003	Pfam Anion-transporting ATPase
HBA75_RS01980	COG1846	Transcriptional regulator
HBA75_RS01985	COG4682	membrane
HBA75_RS02005	COG1597	lipid kinase activity
HBA75_RS02015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBA75_RS02025	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_RS02030	COG2076	Multidrug Resistance protein
HBA75_RS02065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_RS02075	COG0582	viral genome integration into host DNA
HBA75_RS02090	COG3620	sequence-specific DNA binding
HBA75_RS02200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HBA75_RS02230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBA75_RS02230	COG1263	PTS System
HBA75_RS02235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HBA75_RS02250	COG0463	Glycosyl transferase, family 2
HBA75_RS02260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HBA75_RS02260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HBA75_RS02280	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HBA75_RS02300	COG1228	amidohydrolase
HBA75_RS02305	COG1090	epimerase
HBA75_RS02335	COG1988	membrane-bound metal-dependent
HBA75_RS02340	COG1194	a g-specific adenine glycosylase
HBA75_RS02365	COG1132	(ABC) transporter
HBA75_RS02370	COG4129	membrane
HBA75_RS02375	COG0067	glutamate synthase
HBA75_RS02375	COG0070	glutamate synthase
HBA75_RS02375	COG0069	glutamate synthase activity
HBA75_RS02385	COG4555	ABC transporter
HBA75_RS02405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HBA75_RS02410	COG0735	belongs to the Fur family
HBA75_RS02530	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HBA75_RS02555	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HBA75_RS02565	COG2766	serine protein kinase
HBA75_RS02585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBA75_RS02595	COG1585	Membrane protein implicated in regulation of membrane protease activity
HBA75_RS02600	COG2268	Band 7 protein
HBA75_RS02610	COG3290	protein histidine kinase activity
HBA75_RS02615	COG4565	transcriptional regulatory protein
HBA75_RS02620	COG2851	Citrate transporter
HBA75_RS02640	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS02650	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HBA75_RS02655	COG3842	ATPase activity
HBA75_RS02660	COG1175	transmembrane transport
HBA75_RS02665	COG0395	ABC-type sugar transport system, permease component
HBA75_RS02680	COG2801	Transposase and inactivated derivatives
HBA75_RS02685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HBA75_RS02690	COG0745	RESPONSE REGULATOR receiver
HBA75_RS02695	COG5002	protein histidine kinase activity
HBA75_RS02695	COG3850	Histidine kinase
HBA75_RS02705	COG4990	cell redox homeostasis
HBA75_RS02715	COG3290	protein histidine kinase activity
HBA75_RS02720	COG4565	transcriptional regulatory protein
HBA75_RS02725	COG3493	citrate carrier protein
HBA75_RS02730	COG0281	malic enzyme
HBA75_RS02740	COG0697	spore germination
HBA75_RS02745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_RS02755	COG5002	protein histidine kinase activity
HBA75_RS02765	COG0454	-acetyltransferase
HBA75_RS02765	COG0456	acetyltransferase
HBA75_RS02770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HBA75_RS02780	COG3383	formate dehydrogenase (NAD+) activity
HBA75_RS02785	COG2427	Protein of unknown function (DUF1641)
HBA75_RS02800	COG0531	amino acid
HBA75_RS02810	COG0640	Transcriptional regulator
HBA75_RS02815	COG2217	Heavy metal translocating P-type atpase
HBA75_RS02820	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HBA75_RS02835	COG3227	Zinc metalloprotease (Elastase)
HBA75_RS02855	COG2720	vancomycin resistance protein
HBA75_RS02860	COG1316	TRANSCRIPTIONal
HBA75_RS02865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_RS02875	COG0346	lactoylglutathione lyase activity
HBA75_RS02880	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS02885	COG1253	flavin adenine dinucleotide binding
HBA75_RS02890	COG1027	Aspartate ammonia-lyase
HBA75_RS02895	COG1620	l-lactate permease
HBA75_RS02910	COG3104	oligopeptide transport
HBA75_RS02915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_RS02920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_RS02925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_RS02935	COG2226	methyltransferase
HBA75_RS02945	COG3344	reverse transcriptase
HBA75_RS02955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HBA75_RS02960	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HBA75_RS02970	COG4548	von Willebrand factor, type A
HBA75_RS02975	COG0714	Associated with various cellular activities
HBA75_RS02995	COG0531	amino acid
HBA75_RS03000	COG2188	Transcriptional regulator
HBA75_RS03005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBA75_RS03005	COG1263	PTS System
HBA75_RS03010	COG0366	Alpha amylase catalytic
HBA75_RS03025	COG0697	spore germination
HBA75_RS03030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HBA75_RS03035	COG1115	amino acid carrier protein
HBA75_RS03040	COG1126	abc transporter atp-binding protein
HBA75_RS03045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBA75_RS03050	COG0765	amino acid transport
HBA75_RS03055	COG0765	amino acid transport
HBA75_RS03060	COG0833	amino acid
HBA75_RS03085	COG2378	regulation of single-species biofilm formation
HBA75_RS03090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HBA75_RS03095	COG5002	protein histidine kinase activity
HBA75_RS03110	COG0659	secondary active sulfate transmembrane transporter activity
HBA75_RS03125	COG2271	Major facilitator Superfamily
HBA75_RS03130	COG1846	Transcriptional regulator
HBA75_RS03135	COG0477	Major facilitator Superfamily
HBA75_RS03140	COG1609	Transcriptional regulator
HBA75_RS03145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBA75_RS03160	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBA75_RS03165	COG1879	ABC-type sugar transport system periplasmic component
HBA75_RS03190	COG1063	alcohol dehydrogenase
HBA75_RS03255	COG0840	transmembrane signaling receptor activity
HBA75_RS03260	COG3583	domain protein
HBA75_RS03260	COG3584	3D domain protein
HBA75_RS03265	COG1476	TRANSCRIPTIONal
HBA75_RS03285	COG3104	oligopeptide transport
HBA75_RS03290	COG1114	Component of the transport system for branched-chain amino acids
HBA75_RS03305	COG1113	amino acid transport
HBA75_RS03310	COG2252	PERMEase
HBA75_RS03325	COG2153	protein acetylation
HBA75_RS03335	COG0569	domain protein
HBA75_RS03335	COG0475	glutathione-regulated potassium exporter activity
HBA75_RS03345	COG1845	cytochrome c oxidase, subunit III
HBA75_RS03350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HBA75_RS03360	COG0833	amino acid
HBA75_RS03365	COG4990	cell redox homeostasis
HBA75_RS03380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBA75_RS03385	COG0697	spore germination
HBA75_RS03390	COG0531	amino acid
HBA75_RS03405	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HBA75_RS03410	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HBA75_RS03415	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HBA75_RS03415	COG1918	ferrous iron import across plasma membrane
HBA75_RS03420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HBA75_RS03425	COG0573	inorganic phosphate transmembrane transporter activity
HBA75_RS03430	COG0581	inorganic phosphate transmembrane transporter activity
HBA75_RS03440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBA75_RS03560	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HBA75_RS03580	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBA75_RS03585	COG1116	anion transmembrane transporter activity
HBA75_RS03590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBA75_RS03595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBA75_RS03600	COG0352	thiamine-phosphate diphosphorylase activity
HBA75_RS03605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBA75_RS03610	COG2104	thiamine diphosphate biosynthetic process
HBA75_RS03620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HBA75_RS03625	COG0351	phosphomethylpyrimidine kinase
HBA75_RS03665	COG2205	protein histidine kinase activity
HBA75_RS03670	COG2814	Major facilitator Superfamily
HBA75_RS03675	COG1846	Transcriptional regulator
HBA75_RS03685	COG2252	PERMEase
HBA75_RS03690	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS03705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBA75_RS03710	COG1621	beta-fructofuranosidase activity
HBA75_RS03715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBA75_RS03715	COG1263	PTS System
HBA75_RS03720	COG1609	Transcriptional regulator
HBA75_RS03775	COG0778	Nitroreductase
HBA75_RS03780	COG2719	SpoVR family
HBA75_RS03805	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBA75_RS03810	COG1937	Protein conserved in bacteria
HBA75_RS03815	COG0425	Belongs to the sulfur carrier protein TusA family
HBA75_RS03815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_RS03820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_RS03820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_RS03825	COG0425	Belongs to the sulfur carrier protein TusA family
HBA75_RS03830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_RS03830	COG0425	Belongs to the sulfur carrier protein TusA family
HBA75_RS03835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_RS03840	COG2210	Belongs to the sulfur carrier protein TusA family
HBA75_RS03845	COG0730	response to heat
HBA75_RS03855	COG1316	TRANSCRIPTIONal
HBA75_RS03860	COG0604	alcohol dehydrogenase
HBA75_RS03865	COG1283	sodium-dependent phosphate transmembrane transporter activity
HBA75_RS03880	COG3711	transcriptional antiterminator
HBA75_RS03880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBA75_RS03885	COG1447	Phosphotransferase system cellobiose-specific component IIA
HBA75_RS03890	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBA75_RS03910	COG3584	3D domain protein
HBA75_RS03910	COG1388	LysM domain
HBA75_RS03915	COG0577	efflux transmembrane transporter activity
HBA75_RS03920	COG1136	(ABC) transporter
HBA75_RS03930	COG5522	Integral membrane protein (intg_mem_TP0381)
HBA75_RS03945	COG1114	Component of the transport system for branched-chain amino acids
HBA75_RS03950	COG3546	catalase activity
HBA75_RS03985	COG0586	Pfam SNARE associated Golgi protein
HBA75_RS04020	COG0531	amino acid
HBA75_RS04025	COG0475	glutathione-regulated potassium exporter activity
HBA75_RS04035	COG1737	Transcriptional regulator
HBA75_RS04045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBA75_RS04045	COG1263	PTS System
HBA75_RS04055	COG2259	Doxx family
HBA75_RS04075	COG1522	sequence-specific DNA binding
HBA75_RS04080	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HBA75_RS04080	COG0165	Argininosuccinate lyase
HBA75_RS04105	COG1309	transcriptional regulator
HBA75_RS04110	COG2814	Major facilitator Superfamily
HBA75_RS04115	COG1733	regulation of RNA biosynthetic process
HBA75_RS04130	COG4533	DNA binding
HBA75_RS04135	COG2211	Major facilitator Superfamily
HBA75_RS04150	COG0693	protein deglycase activity
HBA75_RS04165	COG0531	amino acid
HBA75_RS04170	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HBA75_RS04180	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_RS04185	COG1132	(ABC) transporter
HBA75_RS04190	COG1132	(ABC) transporter
HBA75_RS04200	COG0765	amino acid transport
HBA75_RS04205	COG1126	abc transporter atp-binding protein
HBA75_RS04220	COG0189	ligase activity
HBA75_RS04260	COG3527	Alpha-acetolactate decarboxylase
HBA75_RS04270	COG0561	phosphatase activity
HBA75_RS04280	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_RS04280	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS04285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HBA75_RS04290	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_RS04305	COG0659	secondary active sulfate transmembrane transporter activity
HBA75_RS04310	COG2244	polysaccharide biosynthetic process
HBA75_RS04335	COG1024	Enoyl-CoA hydratase
HBA75_RS04355	COG1363	Peptidase, m42
HBA75_RS04390	COG0601	transmembrane transport
HBA75_RS04395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBA75_RS04400	COG0444	Belongs to the ABC transporter superfamily
HBA75_RS04405	COG4608	Belongs to the ABC transporter superfamily
HBA75_RS04415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_RS04435	COG0457	Tetratricopeptide repeat
HBA75_RS04545	COG0477	Major facilitator Superfamily
HBA75_RS04550	COG3290	protein histidine kinase activity
HBA75_RS04555	COG4565	transcriptional regulatory protein
HBA75_RS04560	COG3181	Tripartite tricarboxylate transporter family receptor
HBA75_RS04630	COG0789	Transcriptional regulator
HBA75_RS04630	COG4978	Transcriptional regulator
HBA75_RS04650	COG0305	Participates in initiation and elongation during chromosome replication
HBA75_RS04675	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS04690	COG0477	Major facilitator Superfamily
HBA75_RS04720	COG1073	alpha beta
HBA75_RS04765	COG1183	phosphatidylcholine synthase activity
HBA75_RS04780	COG2376	Dihydroxyacetone kinase
HBA75_RS04790	COG2376	Dihydroxyacetone kinase
HBA75_RS04825	COG1388	LysM domain
HBA75_RS04825	COG3584	3D domain protein
HBA75_RS04835	COG2373	Large extracellular alpha-helical protein
HBA75_RS04855	COG0596	Alpha beta hydrolase
HBA75_RS04905	COG1191	sigma factor activity
HBA75_RS04915	COG2208	phosphoserine phosphatase activity
HBA75_RS04920	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HBA75_RS04925	COG5002	protein histidine kinase activity
HBA75_RS04925	COG0784	Response regulator, receiver
HBA75_RS04925	COG2205	protein histidine kinase activity
HBA75_RS04965	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HBA75_RS04985	COG0420	3'-5' exonuclease activity
HBA75_RS04990	COG4717	serine-type aminopeptidase activity
HBA75_RS05005	COG4974	Belongs to the 'phage' integrase family
HBA75_RS05040	COG0346	lactoylglutathione lyase activity
HBA75_RS05045	COG0346	lactoylglutathione lyase activity
HBA75_RS05050	COG0457	Tetratricopeptide repeat
HBA75_RS05060	COG2267	carboxylic ester hydrolase activity
HBA75_RS05090	COG2140	Oxalate decarboxylase
HBA75_RS05100	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HBA75_RS05110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HBA75_RS05120	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HBA75_RS05125	COG1695	Transcriptional regulator
HBA75_RS05135	COG1595	DNA-templated transcription, initiation
HBA75_RS05150	COG3973	AAA domain
HBA75_RS05180	COG4980	gas vesicle protein
HBA75_RS05185	COG0537	adenosine 5'-monophosphoramidase activity
HBA75_RS05190	COG1131	(ABC) transporter
HBA75_RS05195	COG4473	ABC transporter
HBA75_RS05220	COG3402	PFAM membrane-flanked domain
HBA75_RS05225	COG3428	Bacterial PH domain
HBA75_RS05265	COG0697	spore germination
HBA75_RS05270	COG3402	PFAM membrane-flanked domain
HBA75_RS05275	COG3428	Bacterial PH domain
HBA75_RS05280	COG2329	Antibiotic biosynthesis monooxygenase
HBA75_RS05285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBA75_RS05335	COG1309	transcriptional regulator
HBA75_RS05340	COG1511	domain protein
HBA75_RS05380	COG1609	Transcriptional regulator
HBA75_RS05390	COG1234	tRNA 3'-trailer cleavage
HBA75_RS05395	COG0095	Lipoate-protein ligase
HBA75_RS05405	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_RS05415	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HBA75_RS05425	COG4208	sulfate ABC transporter
HBA75_RS05470	COG1408	metallophosphoesterase
HBA75_RS05475	COG1078	dGTPase activity
HBA75_RS05485	COG1595	DNA-templated transcription, initiation
HBA75_RS05490	COG3708	Transcriptional regulator
HBA75_RS05490	COG2207	Transcriptional regulator
HBA75_RS05495	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS05505	COG2205	protein histidine kinase activity
HBA75_RS05510	COG0745	RESPONSE REGULATOR receiver
HBA75_RS05530	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS05535	COG0501	Belongs to the peptidase M48B family
HBA75_RS05540	COG0840	transmembrane signaling receptor activity
HBA75_RS05545	COG3693	PFAM glycoside hydrolase, family 10
HBA75_RS05555	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HBA75_RS05565	COG2224	Isocitrate lyase
HBA75_RS05580	COG1278	Cold shock
HBA75_RS05605	COG0398	Pfam SNARE associated Golgi protein
HBA75_RS05665	COG0179	Fumarylacetoacetate (FAA) hydrolase
HBA75_RS05690	COG0367	asparagine synthase
HBA75_RS05700	COG0753	catalase activity
HBA75_RS05705	COG0004	ammonium transporteR
HBA75_RS05725	COG2996	Protein conserved in bacteria
HBA75_RS05740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_RS05760	COG0561	phosphatase activity
HBA75_RS05780	COG2267	carboxylic ester hydrolase activity
HBA75_RS05800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HBA75_RS05805	COG5504	Zn-dependent protease
HBA75_RS05820	COG0180	Tryptophanyl-tRNA synthetase
HBA75_RS05845	COG0601	transmembrane transport
HBA75_RS05850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBA75_RS05855	COG0444	Belongs to the ABC transporter superfamily
HBA75_RS05860	COG4608	Belongs to the ABC transporter superfamily
HBA75_RS05865	COG0534	Mate efflux family protein
HBA75_RS05870	COG4166	transmembrane transport
HBA75_RS05885	COG0861	Integral membrane protein TerC family
HBA75_RS05905	COG1164	Oligoendopeptidase f
HBA75_RS05920	COG2346	COG2346, Truncated hemoglobins
HBA75_RS05925	COG4116	CYTH
HBA75_RS05935	COG2357	RelA SpoT domain protein
HBA75_RS05945	COG0564	pseudouridine synthase activity
HBA75_RS05960	COG0772	Belongs to the SEDS family
HBA75_RS05965	COG1216	Glycosyl transferase, family 2
HBA75_RS05985	COG0457	Tetratricopeptide repeat
HBA75_RS05985	COG0463	Glycosyl transferase, family 2
HBA75_RS06005	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HBA75_RS06020	COG1091	dTDP-4-dehydrorhamnose reductase activity
HBA75_RS06065	COG2153	protein acetylation
HBA75_RS06075	COG2382	esterase
HBA75_RS06100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBA75_RS06110	COG0512	Glutamine amidotransferase of anthranilate synthase
HBA75_RS06110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HBA75_RS06145	COG1620	l-lactate permease
HBA75_RS06150	COG5634	Uncharacterized conserved protein (DUF2278)
HBA75_RS06200	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBA75_RS06210	COG1476	TRANSCRIPTIONal
HBA75_RS06270	COG1686	Belongs to the peptidase S11 family
HBA75_RS06275	COG0681	Belongs to the peptidase S26 family
HBA75_RS06310	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_RS06320	COG1176	ABC-type spermidine putrescine transport system, permease component I
HBA75_RS06325	COG1177	transmembrane transport
HBA75_RS06340	COG2409	Drug exporters of the RND superfamily
HBA75_RS06350	COG0564	pseudouridine synthase activity
HBA75_RS06360	COG2340	Cysteine-rich secretory protein family
HBA75_RS06365	COG0247	lactate metabolic process
HBA75_RS06370	COG0277	FAD linked oxidase domain protein
HBA75_RS06375	COG3835	regulator
HBA75_RS06385	COG0745	RESPONSE REGULATOR receiver
HBA75_RS06390	COG5002	protein histidine kinase activity
HBA75_RS06395	COG2186	Transcriptional regulator
HBA75_RS06415	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HBA75_RS06425	COG2116	formate transmembrane transporter activity
HBA75_RS06430	COG0861	Integral membrane protein TerC family
HBA75_RS06435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HBA75_RS06445	COG2030	dehydratase
HBA75_RS06465	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS06470	COG3243	poly(R)-hydroxyalkanoic acid synthase
HBA75_RS06480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HBA75_RS06495	COG1840	ABC-type Fe3 transport system, periplasmic component
HBA75_RS06500	COG3842	ATPase activity
HBA75_RS06525	COG1349	DNA-binding transcription factor activity
HBA75_RS06535	COG0235	Class ii aldolase
HBA75_RS06545	COG2861	carbohydrate metabolic process
HBA75_RS06555	COG3852	Histidine kinase
HBA75_RS06560	COG1846	Transcriptional regulator
HBA75_RS06570	COG2318	DinB family
HBA75_RS06575	COG5002	protein histidine kinase activity
HBA75_RS06585	COG0720	synthase
HBA75_RS06600	COG4873	Protein conserved in bacteria
HBA75_RS06630	COG1780	Probably involved in ribonucleotide reductase function
HBA75_RS06635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBA75_RS06640	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBA75_RS06645	COG1725	Transcriptional regulator
HBA75_RS06650	COG1131	(ABC) transporter
HBA75_RS06660	COG1131	(ABC) transporter
HBA75_RS06665	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HBA75_RS06680	COG1522	sequence-specific DNA binding
HBA75_RS06690	COG1335	isochorismatase
HBA75_RS06700	COG1619	proteins homologs of microcin C7 resistance protein MccF
HBA75_RS06705	COG2070	2-Nitropropane dioxygenase
HBA75_RS06710	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HBA75_RS06720	COG1696	Membrane protein involved in D-alanine export
HBA75_RS06745	COG0716	FMN binding
HBA75_RS06800	COG1846	Transcriptional regulator
HBA75_RS06810	COG1301	dicarboxylic acid transport
HBA75_RS06815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HBA75_RS06820	COG4709	membrane
HBA75_RS06825	COG3874	Sporulation protein YtfJ
HBA75_RS06845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBA75_RS06850	COG0028	Belongs to the TPP enzyme family
HBA75_RS06855	COG0440	acetolactate synthase activity
HBA75_RS06930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HBA75_RS06945	COG1183	phosphatidylcholine synthase activity
HBA75_RS06950	COG1368	sulfuric ester hydrolase activity
HBA75_RS06960	COG0019	diaminopimelate decarboxylase activity
HBA75_RS06980	COG0529	Catalyzes the synthesis of activated sulfate
HBA75_RS06985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBA75_RS07005	COG1648	precorrin-2 dehydrogenase activity
HBA75_RS07010	COG0733	neurotransmitter:sodium symporter activity
HBA75_RS07035	COG1757	Na H antiporter
HBA75_RS07050	COG4758	membrane
HBA75_RS07055	COG4585	Histidine kinase
HBA75_RS07060	COG2197	response regulator
HBA75_RS07070	COG1114	Component of the transport system for branched-chain amino acids
HBA75_RS07140	COG0730	response to heat
HBA75_RS07145	COG0306	phosphate transporter
HBA75_RS07150	COG1392	Phosphate transport regulator
HBA75_RS07155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBA75_RS07170	COG3852	Histidine kinase
HBA75_RS07175	COG1801	Protein of unknown function DUF72
HBA75_RS07185	COG0582	viral genome integration into host DNA
HBA75_RS07190	COG5002	protein histidine kinase activity
HBA75_RS07205	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HBA75_RS07205	COG0392	lysyltransferase activity
HBA75_RS07220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HBA75_RS07225	COG1686	Belongs to the peptidase S11 family
HBA75_RS07230	COG2715	membrane protein required for spore maturation
HBA75_RS07235	COG0700	Nucleoside recognition
HBA75_RS07240	COG1187	pseudouridine synthase activity
HBA75_RS07250	COG1333	cytochrome c biogenesis protein
HBA75_RS07255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HBA75_RS07260	COG0745	RESPONSE REGULATOR receiver
HBA75_RS07265	COG5002	protein histidine kinase activity
HBA75_RS07270	COG2096	Adenosyltransferase
HBA75_RS07290	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HBA75_RS07295	COG1141	Ferredoxin
HBA75_RS07305	COG0514	ATP-dependent DNA helicase (RecQ)
HBA75_RS07310	COG1266	CAAX protease self-immunity
HBA75_RS07325	COG0789	Transcriptional regulator
HBA75_RS07335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBA75_RS07355	COG0492	ferredoxin-NADP+ reductase activity
HBA75_RS07360	COG0252	asparaginase activity
HBA75_RS07430	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HBA75_RS07445	COG0142	geranyltranstransferase activity
HBA75_RS07455	COG0142	geranyltranstransferase activity
HBA75_RS07485	COG0457	Tetratricopeptide repeat
HBA75_RS07505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HBA75_RS07510	COG2010	Cytochrome c
HBA75_RS07510	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HBA75_RS07515	COG4347	Protein of unknown function (DUF1405)
HBA75_RS07530	COG2738	Putative neutral zinc metallopeptidase
HBA75_RS07540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_RS07545	COG1694	Mazg nucleotide pyrophosphohydrolase
HBA75_RS07565	COG0438	transferase activity, transferring glycosyl groups
HBA75_RS07600	COG1199	ATP-dependent helicase activity
HBA75_RS07600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBA75_RS07620	COG3935	DnaD domain protein
HBA75_RS07625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HBA75_RS07635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBA75_RS07635	COG4499	WXG100 protein secretion system (Wss), protein YukC
HBA75_RS07690	COG0116	Belongs to the methyltransferase superfamily
HBA75_RS07710	COG0457	Tetratricopeptide repeat
HBA75_RS07730	COG1199	ATP-dependent helicase activity
HBA75_RS07735	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HBA75_RS07745	COG0024	Methionine aminopeptidase
HBA75_RS07755	COG2233	PERMEase
HBA75_RS07760	COG2311	Membrane
HBA75_RS07770	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HBA75_RS07780	COG0456	acetyltransferase
HBA75_RS07815	COG0754	glutathionylspermidine amidase activity
HBA75_RS07830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HBA75_RS07845	COG3944	biosynthesis protein
HBA75_RS07855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HBA75_RS07870	COG1215	transferase activity, transferring glycosyl groups
HBA75_RS07875	COG0438	transferase activity, transferring glycosyl groups
HBA75_RS07890	COG0454	-acetyltransferase
HBA75_RS07910	COG0328	RNA-DNA hybrid ribonuclease activity
HBA75_RS07950	COG3403	YqcI/YcgG family
HBA75_RS07960	COG1280	lysine exporter protein (LysE YggA)
HBA75_RS07980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBA75_RS07985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HBA75_RS07995	COG0475	glutathione-regulated potassium exporter activity
HBA75_RS08000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBA75_RS08005	COG4978	Transcriptional regulator
HBA75_RS08005	COG0789	Transcriptional regulator
HBA75_RS08015	COG2323	membrane
HBA75_RS08020	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HBA75_RS08060	COG1923	regulation of RNA biosynthetic process
HBA75_RS08070	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HBA75_RS08075	COG1360	Flagellar Motor Protein
HBA75_RS08080	COG2201	protein-glutamate methylesterase activity
HBA75_RS08085	COG2198	Histidine kinase
HBA75_RS08085	COG0643	Histidine kinase
HBA75_RS08090	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HBA75_RS08090	COG1776	CheC inhibitor of MCP methylation
HBA75_RS08105	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HBA75_RS08125	COG1256	bacterial-type flagellum assembly
HBA75_RS08130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HBA75_RS08135	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HBA75_RS08150	COG1815	bacterial-type flagellum-dependent cell motility
HBA75_RS08155	COG1558	bacterial-type flagellum-dependent cell motility
HBA75_RS08165	COG1766	The M ring may be actively involved in energy transduction
HBA75_RS08170	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HBA75_RS08180	COG1157	protein secretion by the type III secretion system
HBA75_RS08215	COG0835	chemotaxis
HBA75_RS08215	COG0784	Response regulator, receiver
HBA75_RS08225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HBA75_RS08230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HBA75_RS08235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HBA75_RS08240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HBA75_RS08245	COG0741	lytic transglycosylase activity
HBA75_RS08255	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HBA75_RS08260	COG1776	CheC inhibitor of MCP methylation
HBA75_RS08260	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HBA75_RS08270	COG1338	Plays a role in the flagellum-specific transport system
HBA75_RS08275	COG1987	bacterial-type flagellum assembly
HBA75_RS08285	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HBA75_RS08290	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HBA75_RS08295	COG1419	protein localization to endoplasmic reticulum
HBA75_RS08300	COG4786	Flagellar basal body rod
HBA75_RS08305	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HBA75_RS08350	COG2329	Antibiotic biosynthesis monooxygenase
HBA75_RS08375	COG0583	DNA-binding transcription factor activity
HBA75_RS08395	COG1234	tRNA 3'-trailer cleavage
HBA75_RS08425	COG1686	Belongs to the peptidase S11 family
HBA75_RS08430	COG0406	alpha-ribazole phosphatase activity
HBA75_RS08460	COG0367	asparagine synthase
HBA75_RS08490	COG1802	Transcriptional regulator
HBA75_RS08495	COG0697	spore germination
HBA75_RS08505	COG0523	cobalamin synthesis protein
HBA75_RS08510	COG0701	Predicted permease
HBA75_RS08525	COG1757	Na H antiporter
HBA75_RS08530	COG0789	Transcriptional regulator
HBA75_RS08560	COG0534	Mate efflux family protein
HBA75_RS08565	COG3340	Belongs to the peptidase S51 family
HBA75_RS08585	COG0785	Cytochrome C biogenesis protein
HBA75_RS08590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HBA75_RS08610	COG2733	membrane
HBA75_RS08645	COG1131	(ABC) transporter
HBA75_RS08665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBA75_RS08670	COG0528	UMP kinase activity
HBA75_RS08680	COG1027	Aspartate ammonia-lyase
HBA75_RS08685	COG2801	Transposase and inactivated derivatives
HBA75_RS08700	COG0281	malic enzyme
HBA75_RS08705	COG4191	Histidine kinase
HBA75_RS08710	COG0784	Response regulator, receiver
HBA75_RS08765	COG2814	Major facilitator Superfamily
HBA75_RS08780	COG1695	Transcriptional regulator
HBA75_RS08795	COG0477	Major facilitator Superfamily
HBA75_RS08810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBA75_RS08830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HBA75_RS08850	COG0733	neurotransmitter:sodium symporter activity
HBA75_RS08860	COG5566	PFAM Mor transcription activator
HBA75_RS08865	COG2323	membrane
HBA75_RS08885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HBA75_RS08895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBA75_RS08900	COG0028	Belongs to the TPP enzyme family
HBA75_RS08920	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBA75_RS08940	COG2814	Major facilitator Superfamily
HBA75_RS08945	COG3384	dioxygenase
HBA75_RS08955	COG3279	Response regulator of the LytR AlgR family
HBA75_RS08960	COG0427	acetyl-CoA hydrolase
HBA75_RS08980	COG4166	transmembrane transport
HBA75_RS08985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_RS09005	COG1914	H( )-stimulated, divalent metal cation uptake system
HBA75_RS09020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBA75_RS09025	COG0531	amino acid
HBA75_RS09055	COG2309	aminopeptidase activity
HBA75_RS09070	COG0456	acetyltransferase
HBA75_RS09120	COG1266	CAAX protease self-immunity
HBA75_RS09125	COG1309	transcriptional regulator
HBA75_RS09130	COG2390	Transcriptional regulator
HBA75_RS09140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_RS09145	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HBA75_RS09155	COG4846	Membrane protein involved in cytochrome C biogenesis
HBA75_RS09175	COG0583	DNA-binding transcription factor activity
HBA75_RS09190	COG0006	proline dipeptidase activity
HBA75_RS09200	COG2132	Multicopper oxidase
HBA75_RS09215	COG1309	transcriptional regulator
HBA75_RS09220	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HBA75_RS09305	COG1114	Component of the transport system for branched-chain amino acids
HBA75_RS09315	COG1276	copper resistance
HBA75_RS09315	COG2372	response to copper ion
HBA75_RS09320	COG4549	nuclear export factor GLE1
HBA75_RS09340	COG0583	DNA-binding transcription factor activity
HBA75_RS09345	COG1959	2 iron, 2 sulfur cluster binding
HBA75_RS09355	COG0778	Nitroreductase
HBA75_RS09365	COG0628	permease
HBA75_RS09375	COG1231	oxidoreductase activity
HBA75_RS09380	COG0523	cobalamin synthesis protein
HBA75_RS09390	COG0411	ABC transporter
HBA75_RS09410	COG0583	DNA-binding transcription factor activity
HBA75_RS09440	COG1271	oxidase subunit
HBA75_RS09445	COG1294	oxidase, subunit
HBA75_RS09455	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HBA75_RS09465	COG1216	Glycosyl transferase, family 2
HBA75_RS09505	COG1686	Belongs to the peptidase S11 family
HBA75_RS09520	COG0791	NLP P60 protein
HBA75_RS09520	COG1388	LysM domain
HBA75_RS09530	COG1132	(ABC) transporter
HBA75_RS09535	COG0745	RESPONSE REGULATOR receiver
HBA75_RS09540	COG5002	protein histidine kinase activity
HBA75_RS09550	COG0300	oxidoreductase activity
HBA75_RS09580	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS09585	COG0460	homoserine dehydrogenase
HBA75_RS09610	COG1316	TRANSCRIPTIONal
HBA75_RS09620	COG0745	RESPONSE REGULATOR receiver
HBA75_RS09625	COG5002	protein histidine kinase activity
HBA75_RS09640	COG1285	pathogenesis
HBA75_RS09645	COG1247	-acetyltransferase
HBA75_RS09655	COG4264	IucA IucC family
HBA75_RS09660	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_RS09675	COG1082	Xylose isomerase domain protein TIM barrel
HBA75_RS09685	COG2814	Major facilitator Superfamily
HBA75_RS09690	COG1279	arginine transmembrane transporter activity
HBA75_RS09695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_RS09705	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBA75_RS09745	COG0577	efflux transmembrane transporter activity
HBA75_RS09750	COG2002	toxin-antitoxin pair type II binding
HBA75_RS09755	COG1404	Belongs to the peptidase S8 family
HBA75_RS09760	COG0640	Transcriptional regulator
HBA75_RS09765	COG0667	Aldo Keto reductase
HBA75_RS09770	COG2814	Major facilitator Superfamily
HBA75_RS09795	COG0840	transmembrane signaling receptor activity
HBA75_RS09810	COG3949	Membrane
HBA75_RS09815	COG0783	Belongs to the Dps family
HBA75_RS09830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBA75_RS09840	COG1231	oxidoreductase activity
HBA75_RS09845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_RS09850	COG4989	oxidoreductase activity
HBA75_RS09860	COG0523	cobalamin synthesis protein
HBA75_RS09865	COG0456	acetyltransferase
HBA75_RS09870	COG0803	Belongs to the bacterial solute-binding protein 9 family
HBA75_RS09885	COG0702	epimerase
HBA75_RS09895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBA75_RS09905	COG4166	transmembrane transport
HBA75_RS09930	COG5337	Spore coat protein CotH
HBA75_RS09935	COG1051	belongs to the nudix hydrolase family
HBA75_RS09940	COG0586	Pfam SNARE associated Golgi protein
HBA75_RS09945	COG2244	polysaccharide biosynthetic process
HBA75_RS09955	COG0701	Predicted permease
HBA75_RS09960	COG3689	TIGRFAM TIGR03943 family protein
HBA75_RS09965	COG1607	acyl-coa hydrolase
HBA75_RS09975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBA75_RS09990	COG0702	epimerase
HBA75_RS09995	COG2839	Protein conserved in bacteria
HBA75_RS10000	COG1253	flavin adenine dinucleotide binding
HBA75_RS10015	COG1114	Component of the transport system for branched-chain amino acids
HBA75_RS10020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBA75_RS10040	COG0860	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS10050	COG1876	peptidase activity
HBA75_RS10060	COG2211	Major facilitator Superfamily
HBA75_RS10075	COG0860	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS10085	COG0561	phosphatase activity
HBA75_RS10100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBA75_RS10115	COG1819	glycosyl
HBA75_RS10120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_RS10125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_RS10155	COG0456	acetyltransferase
HBA75_RS10190	COG4499	WXG100 protein secretion system (Wss), protein YukC
HBA75_RS10270	COG3874	Sporulation protein YtfJ
HBA75_RS10275	COG2801	Transposase and inactivated derivatives
HBA75_RS10305	COG2226	methyltransferase
HBA75_RS10325	COG1082	Xylose isomerase domain protein TIM barrel
HBA75_RS10330	COG0346	lactoylglutathione lyase activity
HBA75_RS10340	COG0604	alcohol dehydrogenase
HBA75_RS10360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBA75_RS10360	COG0426	domain, Protein
HBA75_RS10370	COG0386	Belongs to the glutathione peroxidase family
HBA75_RS10375	COG1305	Transglutaminase-like
HBA75_RS10380	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
HBA75_RS10385	COG0714	Associated with various cellular activities
HBA75_RS10390	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBA75_RS10395	COG1140	nitrate reductase beta subunit
HBA75_RS10400	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HBA75_RS10405	COG2181	nitrate reductase activity
HBA75_RS10410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBA75_RS10415	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBA75_RS10420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HBA75_RS10425	COG0303	'Molybdopterin
HBA75_RS10430	COG0314	molybdopterin synthase activity
HBA75_RS10440	COG2223	nitrite transmembrane transporter activity
HBA75_RS10460	COG1648	precorrin-2 dehydrogenase activity
HBA75_RS10470	COG1587	Uroporphyrinogen-III synthase
HBA75_RS10470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HBA75_RS10475	COG2146	nitrite reductase [NAD(P)H] activity
HBA75_RS10480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBA75_RS10535	COG2359	stage V sporulation protein S
HBA75_RS10560	COG0457	Tetratricopeptide repeat
HBA75_RS10575	COG1418	mRNA catabolic process
HBA75_RS10580	COG0488	(ABC) transporter
HBA75_RS10595	COG0629	single-stranded DNA binding
HBA75_RS10610	COG1413	lyase activity
HBA75_RS10630	COG2136	Putative SAM-dependent methyltransferase
HBA75_RS10630	COG2521	methyltransferase
HBA75_RS10635	COG0018	arginyl-trna synthetase
HBA75_RS10670	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS10695	COG0017	Asparaginyl-tRNA synthetase
HBA75_RS10700	COG0733	neurotransmitter:sodium symporter activity
HBA75_RS10725	COG2610	gluconate transmembrane transporter activity
HBA75_RS10735	COG1794	racemase activity, acting on amino acids and derivatives
HBA75_RS10745	COG0456	acetyltransferase
HBA75_RS10755	COG3655	Transcriptional regulator
HBA75_RS10760	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HBA75_RS10770	COG1131	(ABC) transporter
HBA75_RS10775	COG4473	ABC transporter
HBA75_RS10785	COG0546	phosphoglycolate phosphatase activity
HBA75_RS10800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HBA75_RS10815	COG0768	penicillin binding
HBA75_RS10825	COG0204	Acyl-transferase
HBA75_RS10830	COG1272	protein, Hemolysin III
HBA75_RS10840	COG0805	protein transport
HBA75_RS10850	COG1307	EDD domain protein, DegV family
HBA75_RS10860	COG1999	signal sequence binding
HBA75_RS10865	COG0071	Belongs to the small heat shock protein (HSP20) family
HBA75_RS10870	COG0367	asparagine synthase
HBA75_RS10890	COG0860	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS10895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_RS10900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBA75_RS10925	COG1335	isochorismatase
HBA75_RS10945	COG0668	transmembrane transport
HBA75_RS10950	COG2203	Gaf domain
HBA75_RS10950	COG4585	Histidine kinase
HBA75_RS10955	COG2197	response regulator
HBA75_RS10960	COG1737	Transcriptional regulator
HBA75_RS10980	COG1064	alcohol dehydrogenase
HBA75_RS10995	COG1070	Carbohydrate kinase
HBA75_RS11005	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HBA75_RS11040	COG1125	glycine betaine transport
HBA75_RS11040	COG0517	IMP dehydrogenase activity
HBA75_RS11045	COG1174	glycine betaine transport
HBA75_RS11080	COG1253	flavin adenine dinucleotide binding
HBA75_RS11085	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_RS11090	COG5506	Protein of unknown function (DUF1694)
HBA75_RS11105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HBA75_RS11110	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBA75_RS11115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBA75_RS11120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HBA75_RS11125	COG0456	acetyltransferase
HBA75_RS11130	COG3829	transcription factor binding
HBA75_RS11140	COG1509	lysine 2,3-aminomutase activity
HBA75_RS11175	COG3064	Membrane
HBA75_RS11175	COG4991	sh3 domain protein
HBA75_RS11175	COG0515	serine threonine protein kinase
HBA75_RS11185	COG0671	phosphoesterase, PA-phosphatase related
HBA75_RS11190	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBA75_RS11195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HBA75_RS11295	COG4499	WXG100 protein secretion system (Wss), protein YukC
HBA75_RS11295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBA75_RS11305	COG2814	Major facilitator Superfamily
HBA75_RS11310	COG4841	protein insertion into membrane
HBA75_RS11315	COG0372	Belongs to the citrate synthase family
HBA75_RS11320	COG2079	MmgE PrpD family protein
HBA75_RS11325	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HBA75_RS11330	COG1960	acyl-CoA dehydrogenase activity
HBA75_RS11335	COG2084	Dehydrogenase
HBA75_RS11345	COG1280	lysine exporter protein (LysE YggA)
HBA75_RS11350	COG1024	Enoyl-CoA hydratase
HBA75_RS11365	COG0420	3'-5' exonuclease activity
HBA75_RS11370	COG0419	ATPase involved in DNA repair
HBA75_RS11400	COG2223	nitrite transmembrane transporter activity
HBA75_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS11410	COG1169	isochorismate synthase
HBA75_RS11415	COG1021	2,3-dihydroxybenzoate-AMP ligase
HBA75_RS11420	COG1535	isochorismatase
HBA75_RS11420	COG3433	isochorismatase activity
HBA75_RS11425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBA75_RS11430	COG3251	PFAM MbtH domain protein
HBA75_RS11435	COG2814	Major facilitator Superfamily
HBA75_RS11450	COG0776	regulation of translation
HBA75_RS11460	COG2318	DinB family
HBA75_RS11470	COG1115	amino acid carrier protein
HBA75_RS11490	COG1187	pseudouridine synthase activity
HBA75_RS11495	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HBA75_RS11500	COG1136	(ABC) transporter
HBA75_RS11510	COG2814	Major facilitator Superfamily
HBA75_RS11525	COG0028	Belongs to the TPP enzyme family
HBA75_RS11570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBA75_RS11590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_RS11625	COG1247	-acetyltransferase
HBA75_RS11660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_RS11690	COG0583	DNA-binding transcription factor activity
HBA75_RS11695	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HBA75_RS11715	COG0583	DNA-binding transcription factor activity
HBA75_RS11720	COG2258	MOSC domain
HBA75_RS11735	COG1132	(ABC) transporter
HBA75_RS11770	COG1396	sequence-specific DNA binding
HBA75_RS11800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBA75_RS11805	COG1595	DNA-templated transcription, initiation
HBA75_RS11830	COG1649	PFAM Uncharacterised BCR, COG1649
HBA75_RS11855	COG2971	BadF BadG BcrA BcrD
HBA75_RS11865	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HBA75_RS11875	COG1846	Transcriptional regulator
HBA75_RS11890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_RS11920	COG2002	toxin-antitoxin pair type II binding
HBA75_RS11960	COG0582	viral genome integration into host DNA
HBA75_RS11985	COG0500	methyltransferase
HBA75_RS11985	COG3615	Tellurite resistance protein tehB
HBA75_RS11995	COG2226	methyltransferase
HBA75_RS12000	COG3961	Belongs to the TPP enzyme family
HBA75_RS12005	COG1846	Transcriptional regulator
HBA75_RS12035	COG2195	Cleaves the N-terminal amino acid of tripeptides
HBA75_RS12065	COG2002	toxin-antitoxin pair type II binding
HBA75_RS12080	COG0730	response to heat
HBA75_RS12085	COG0110	maltose O-acetyltransferase activity
HBA75_RS12090	COG1686	Belongs to the peptidase S11 family
HBA75_RS12105	COG2814	Major facilitator Superfamily
HBA75_RS12125	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS12185	COG3344	reverse transcriptase
HBA75_RS12215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_RS12270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HBA75_RS12275	COG0768	penicillin binding
HBA75_RS12280	COG1595	DNA-templated transcription, initiation
HBA75_RS12290	COG0768	penicillin binding
HBA75_RS12305	COG1408	metallophosphoesterase
HBA75_RS12315	COG1131	(ABC) transporter
HBA75_RS12325	COG1309	transcriptional regulator
HBA75_RS12340	COG1960	acyl-CoA dehydrogenase activity
HBA75_RS12345	COG0439	Biotin carboxylase
HBA75_RS12350	COG0511	ligase activity, forming carbon-carbon bonds
HBA75_RS12355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HBA75_RS12360	COG1024	Enoyl-CoA hydratase
HBA75_RS12365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HBA75_RS12370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBA75_RS12380	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS12395	COG0572	uridine kinase
HBA75_RS12405	COG2318	DinB family
HBA75_RS12410	COG1686	Belongs to the peptidase S11 family
HBA75_RS12435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HBA75_RS12450	COG3227	Zinc metalloprotease (Elastase)
HBA75_RS12455	COG2207	Transcriptional regulator
HBA75_RS12500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HBA75_RS12540	COG2814	Major facilitator Superfamily
HBA75_RS12545	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS12550	COG1733	regulation of RNA biosynthetic process
HBA75_RS12605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_RS12615	COG2368	4-hydroxyphenylacetate
HBA75_RS12630	COG1063	alcohol dehydrogenase
HBA75_RS12640	COG2323	membrane
HBA75_RS12655	COG3386	PFAM SMP-30 Gluconolaconase
HBA75_RS12665	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
HBA75_RS12670	COG3773	Cell wall hydrolase
HBA75_RS12675	COG0596	Alpha beta hydrolase
HBA75_RS12690	COG0745	RESPONSE REGULATOR receiver
HBA75_RS12695	COG2205	protein histidine kinase activity
HBA75_RS12730	COG1136	(ABC) transporter
HBA75_RS12735	COG0577	efflux transmembrane transporter activity
HBA75_RS12770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_RS12780	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBA75_RS12840	COG2124	cytochrome p450
HBA75_RS12875	COG0561	phosphatase activity
HBA75_RS12880	COG5002	protein histidine kinase activity
HBA75_RS12895	COG1819	glycosyl
HBA75_RS12900	COG1794	racemase activity, acting on amino acids and derivatives
HBA75_RS12925	COG2205	protein histidine kinase activity
HBA75_RS12940	COG0604	alcohol dehydrogenase
HBA75_RS12945	COG0671	phosphoesterase, PA-phosphatase related
HBA75_RS13010	COG2132	Multicopper oxidase
HBA75_RS13020	COG0789	Transcriptional regulator
HBA75_RS13040	COG0584	glycerophosphoryl diester phosphodiesterase
HBA75_RS13060	COG2801	Transposase and inactivated derivatives
HBA75_RS13075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_RS13080	COG0697	spore germination
HBA75_RS13125	COG2223	nitrite transmembrane transporter activity
HBA75_RS13140	COG0592	DNA-directed DNA polymerase activity
HBA75_RS13160	COG3878	Protein conserved in bacteria
HBA75_RS13180	COG4667	esterase of the alpha-beta hydrolase superfamily
HBA75_RS13220	COG0322	excinuclease ABC activity
HBA75_RS13270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBA75_RS13305	COG1011	Hydrolase
HBA75_RS13310	COG0745	RESPONSE REGULATOR receiver
HBA75_RS13315	COG5002	protein histidine kinase activity
HBA75_RS13330	COG1136	(ABC) transporter
HBA75_RS13335	COG0577	efflux transmembrane transporter activity
HBA75_RS13340	COG1073	alpha beta
HBA75_RS13350	COG2801	Transposase and inactivated derivatives
HBA75_RS13370	COG0076	glutamate decarboxylase activity
HBA75_RS13390	COG3227	Zinc metalloprotease (Elastase)
HBA75_RS13395	COG0737	Belongs to the 5'-nucleotidase family
HBA75_RS13410	COG0201	protein transport
HBA75_RS13415	COG0697	spore germination
HBA75_RS13420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_RS13460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_RS13475	COG2959	enzyme of heme biosynthesis
HBA75_RS13535	COG1309	transcriptional regulator
HBA75_RS13560	COG3284	Transcriptional regulator
HBA75_RS13580	COG1349	DNA-binding transcription factor activity
HBA75_RS13595	COG1959	2 iron, 2 sulfur cluster binding
HBA75_RS13610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBA75_RS13615	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBA75_RS13620	COG0022	dehydrogenase e1 component
HBA75_RS13625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HBA75_RS13635	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS13640	COG0456	acetyltransferase
HBA75_RS13640	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBA75_RS13680	COG4176	ABC-type proline glycine betaine transport system permease component
HBA75_RS13685	COG4175	Glycine betaine
HBA75_RS13685	COG0517	IMP dehydrogenase activity
HBA75_RS13715	COG2153	protein acetylation
HBA75_RS13720	COG3397	chitin binding
HBA75_RS13725	COG1819	glycosyl
HBA75_RS13745	COG2205	protein histidine kinase activity
HBA75_RS13750	COG2226	methyltransferase
HBA75_RS13755	COG2315	Protein conserved in bacteria
HBA75_RS13800	COG0456	acetyltransferase
HBA75_RS13805	COG3973	AAA domain
HBA75_RS13820	COG0514	ATP-dependent DNA helicase (RecQ)
HBA75_RS13860	COG2801	Transposase and inactivated derivatives
HBA75_RS13875	COG4637	Psort location Cytoplasmic, score
HBA75_RS13890	COG3397	chitin binding
HBA75_RS13905	COG1162	GTPase activity
HBA75_RS13910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBA75_RS13915	COG1115	amino acid carrier protein
HBA75_RS13920	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_RS13925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBA75_RS13935	COG3938	Belongs to the proline racemase family
HBA75_RS13940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBA75_RS13985	COG0586	Pfam SNARE associated Golgi protein
HBA75_RS13995	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HBA75_RS14005	COG4166	transmembrane transport
HBA75_RS14020	COG4948	Mandelate Racemase Muconate Lactonizing
HBA75_RS14035	COG0667	Aldo Keto reductase
HBA75_RS14080	COG3850	Histidine kinase
HBA75_RS14080	COG5002	protein histidine kinase activity
HBA75_RS14085	COG0745	RESPONSE REGULATOR receiver
HBA75_RS14120	COG1164	Oligoendopeptidase f
HBA75_RS14125	COG1307	EDD domain protein, DegV family
HBA75_RS14165	COG2814	Major facilitator Superfamily
HBA75_RS14175	COG1664	Polymer-forming cytoskeletal
HBA75_RS14180	COG0789	Transcriptional regulator
HBA75_RS14185	COG4533	DNA binding
HBA75_RS14190	COG2814	Major facilitator Superfamily
HBA75_RS14190	COG0477	Major facilitator Superfamily
HBA75_RS14210	COG2261	transglycosylase associated protein
HBA75_RS14225	COG2226	methyltransferase
HBA75_RS14260	COG0436	Aminotransferase
HBA75_RS14265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HBA75_RS14275	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HBA75_RS14315	COG0628	permease
HBA75_RS14325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBA75_RS14330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBA75_RS14335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBA75_RS14375	COG2746	aminoglycoside 3-N-acetyltransferase activity
HBA75_RS14400	COG2318	DinB family
HBA75_RS14420	COG4912	Dna alkylation repair
HBA75_RS14425	COG0346	lactoylglutathione lyase activity
HBA75_RS14445	COG0861	Integral membrane protein TerC family
HBA75_RS14450	COG1368	sulfuric ester hydrolase activity
HBA75_RS14455	COG0488	(ABC) transporter
HBA75_RS14460	COG2409	Drug exporters of the RND superfamily
HBA75_RS14460	COG1033	growth of symbiont in host cell
HBA75_RS14465	COG1309	transcriptional regulator
HBA75_RS14475	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS14490	COG0287	Prephenate dehydrogenase
HBA75_RS14505	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HBA75_RS14505	COG1605	Chorismate mutase
HBA75_RS14550	COG1388	LysM domain
HBA75_RS14550	COG3584	3D domain protein
HBA75_RS14560	COG0346	lactoylglutathione lyase activity
HBA75_RS14565	COG0277	FAD linked oxidase domain protein
HBA75_RS14595	COG1879	ABC-type sugar transport system periplasmic component
HBA75_RS14600	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBA75_RS14605	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBA75_RS14615	COG2390	Transcriptional regulator
HBA75_RS14620	COG1070	Carbohydrate kinase
HBA75_RS14640	COG2329	Antibiotic biosynthesis monooxygenase
HBA75_RS14660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_RS14675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBA75_RS14680	COG4187	Peptidase family M20/M25/M40
HBA75_RS14685	COG1414	Transcriptional regulator
HBA75_RS14690	COG0833	amino acid
HBA75_RS14740	COG2720	vancomycin resistance protein
HBA75_RS14745	COG1785	Belongs to the alkaline phosphatase family
HBA75_RS14755	COG3655	Transcriptional regulator
HBA75_RS14780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_RS14785	COG0346	lactoylglutathione lyase activity
HBA75_RS14810	COG0714	Associated with various cellular activities
HBA75_RS14835	COG0463	Glycosyl transferase, family 2
HBA75_RS14865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBA75_RS14870	COG0753	catalase activity
HBA75_RS14915	COG0714	Associated with various cellular activities
HBA75_RS14980	COG0778	Nitroreductase
HBA75_RS14985	COG1846	Transcriptional regulator
HBA75_RS15010	COG4884	unkown
HBA75_RS15010	COG3831	ATPase activity
HBA75_RS15035	COG0456	acetyltransferase
HBA75_RS15050	COG0697	spore germination
HBA75_RS15055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_RS15095	COG0730	response to heat
HBA75_RS15110	COG0833	amino acid
HBA75_RS15120	COG4335	DNA alkylation repair
HBA75_RS15175	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS15185	COG1984	allophanate hydrolase subunit 2
HBA75_RS15190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HBA75_RS15195	COG1414	Transcriptional regulator
HBA75_RS15210	COG0640	Transcriptional regulator
HBA75_RS15225	COG1960	acyl-CoA dehydrogenase activity
HBA75_RS15245	COG2801	Transposase and inactivated derivatives
HBA75_RS15260	COG2801	Transposase and inactivated derivatives
HBA75_RS15285	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HBA75_RS15305	COG2801	Transposase and inactivated derivatives
HBA75_RS15325	COG0574	Belongs to the PEP-utilizing enzyme family
HBA75_RS15325	COG3848	Pyruvate phosphate dikinase
HBA75_RS15330	COG1819	glycosyl
HBA75_RS15335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_RS15340	COG5577	PFAM Coat F domain
HBA75_RS15345	COG3403	YqcI/YcgG family
HBA75_RS15350	COG1280	lysine exporter protein (LysE YggA)
HBA75_RS15355	COG1113	amino acid transport
HBA75_RS15385	COG1063	alcohol dehydrogenase
HBA75_RS15395	COG1027	Aspartate ammonia-lyase
HBA75_RS15400	COG0252	asparaginase activity
HBA75_RS15405	COG1396	sequence-specific DNA binding
HBA75_RS15450	COG5002	protein histidine kinase activity
HBA75_RS15475	COG2207	Transcriptional regulator
HBA75_RS15490	COG0322	excinuclease ABC activity
HBA75_RS15495	COG0531	amino acid
HBA75_RS15500	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBA75_RS15510	COG0281	malic enzyme
HBA75_RS15540	COG0531	amino acid
HBA75_RS15545	COG0697	spore germination
HBA75_RS15550	COG0784	Response regulator, receiver
HBA75_RS15555	COG4191	Histidine kinase
HBA75_RS15560	COG2066	Belongs to the glutaminase family
HBA75_RS15565	COG1115	amino acid carrier protein
HBA75_RS15575	COG2124	cytochrome p450
HBA75_RS15590	COG1309	transcriptional regulator
HBA75_RS15595	COG2814	Major facilitator Superfamily
HBA75_RS15600	COG1309	transcriptional regulator
HBA75_RS15610	COG1522	sequence-specific DNA binding
HBA75_RS15625	COG0346	lactoylglutathione lyase activity
HBA75_RS15675	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS15730	COG2814	Major facilitator Superfamily
HBA75_RS15740	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HBA75_RS15750	COG1690	Belongs to the RtcB family
HBA75_RS15760	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HBA75_RS15785	COG0577	efflux transmembrane transporter activity
HBA75_RS15805	COG5002	protein histidine kinase activity
HBA75_RS15805	COG3850	Histidine kinase
HBA75_RS15815	COG2364	Membrane
HBA75_RS15820	COG1846	Transcriptional regulator
HBA75_RS15825	COG0456	acetyltransferase
HBA75_RS15830	COG2808	Putative FMN-binding domain
HBA75_RS15835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_RS15870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HBA75_RS15915	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_RS15915	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS16020	COG1876	peptidase activity
HBA75_RS16025	COG2843	Capsule synthesis protein
HBA75_RS16035	COG0477	Major facilitator Superfamily
HBA75_RS16050	COG1846	Transcriptional regulator
HBA75_RS16055	COG2814	Major facilitator Superfamily
HBA75_RS16065	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HBA75_RS16070	COG1131	(ABC) transporter
HBA75_RS16090	COG2031	fatty acid transporter
HBA75_RS16100	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBA75_RS16155	COG1288	antiporter activity
HBA75_RS16160	COG2356	endonuclease I
HBA75_RS16185	COG1733	regulation of RNA biosynthetic process
HBA75_RS16190	COG0778	Nitroreductase
HBA75_RS16200	COG0469	pyruvate kinase activity
HBA75_RS16220	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS16230	COG1131	(ABC) transporter
HBA75_RS16255	COG1011	Hydrolase
HBA75_RS16295	COG0628	permease
HBA75_RS16325	COG0500	methyltransferase
HBA75_RS16365	COG1253	flavin adenine dinucleotide binding
HBA75_RS16370	COG0789	Transcriptional regulator
HBA75_RS16380	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HBA75_RS16410	COG0697	spore germination
HBA75_RS16415	COG1357	PFAM Pentapeptide repeats (8 copies)
HBA75_RS16420	COG3813	Protein conserved in bacteria
HBA75_RS16425	COG2706	6-phosphogluconolactonase activity
HBA75_RS16430	COG1070	Carbohydrate kinase
HBA75_RS16445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HBA75_RS16450	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HBA75_RS16455	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBA75_RS16460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HBA75_RS16465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HBA75_RS16470	COG0604	alcohol dehydrogenase
HBA75_RS16475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBA75_RS16485	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS16500	COG0840	transmembrane signaling receptor activity
HBA75_RS16510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBA75_RS16510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBA75_RS16515	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HBA75_RS16515	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HBA75_RS16520	COG1733	regulation of RNA biosynthetic process
HBA75_RS16535	COG0656	L-ascorbic acid biosynthetic process
HBA75_RS16540	COG2814	Major facilitator Superfamily
HBA75_RS16565	COG2824	Alkylphosphonate utilization operon protein PhnA
HBA75_RS16570	COG0659	secondary active sulfate transmembrane transporter activity
HBA75_RS16585	COG0814	amino acid
HBA75_RS16610	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS16625	COG1733	regulation of RNA biosynthetic process
HBA75_RS16630	COG2188	Transcriptional regulator
HBA75_RS16635	COG0673	inositol 2-dehydrogenase activity
HBA75_RS16640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HBA75_RS16645	COG1733	regulation of RNA biosynthetic process
HBA75_RS16650	COG1733	regulation of RNA biosynthetic process
HBA75_RS16685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_RS16710	COG0384	phenazine biosynthesis protein PhzF
HBA75_RS16720	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS16740	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_RS16745	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBA75_RS16750	COG1733	regulation of RNA biosynthetic process
HBA75_RS16765	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS16770	COG2801	Transposase and inactivated derivatives
HBA75_RS16790	COG1191	sigma factor activity
HBA75_RS16880	COG1151	hydroxylamine reductase activity
HBA75_RS16890	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_RS16890	COG3757	hydrolase, family 25
HBA75_RS16920	COG2072	flavoprotein involved in K transport
HBA75_RS16955	COG1113	amino acid transport
HBA75_RS16960	COG2814	Major facilitator Superfamily
HBA75_RS16995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HBA75_RS17000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HBA75_RS17010	COG1247	-acetyltransferase
HBA75_RS17015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_RS17020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_RS17025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_RS17030	COG3739	integral membrane protein
HBA75_RS17050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_RS17065	COG0583	DNA-binding transcription factor activity
HBA75_RS17085	COG1193	negative regulation of DNA recombination
HBA75_RS17095	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HBA75_RS17100	COG1164	Oligoendopeptidase f
HBA75_RS17125	COG3781	membrane
HBA75_RS17140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HBA75_RS17165	COG0584	glycerophosphoryl diester phosphodiesterase
HBA75_RS17175	COG0640	Transcriptional regulator
HBA75_RS17180	COG0604	alcohol dehydrogenase
HBA75_RS17190	COG0457	Tetratricopeptide repeat
HBA75_RS17205	COG0277	FAD linked oxidase domain protein
HBA75_RS17230	COG1183	phosphatidylcholine synthase activity
HBA75_RS17235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_RS17235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_RS17240	COG1252	NADH dehydrogenase
HBA75_RS17250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HBA75_RS17260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HBA75_RS17270	COG0457	Tetratricopeptide repeat
HBA75_RS17300	COG1309	transcriptional regulator
HBA75_RS17345	COG3852	Histidine kinase
HBA75_RS17355	COG1285	pathogenesis
HBA75_RS17365	COG2514	catechol 2,3-dioxygenase activity
HBA75_RS17370	COG2720	vancomycin resistance protein
HBA75_RS17405	COG0716	FMN binding
HBA75_RS17415	COG0494	nUDIX hydrolase
HBA75_RS17465	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS17475	COG0165	Argininosuccinate lyase
HBA75_RS17490	COG4145	pantothenate transmembrane transporter activity
HBA75_RS17500	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_RS17505	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS17515	COG1657	PFAM Prenyltransferase squalene oxidase
HBA75_RS17520	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HBA75_RS17525	COG2962	Rard protein
HBA75_RS17535	COG3326	Membrane
HBA75_RS17550	COG0489	protein tyrosine kinase activity
HBA75_RS17560	COG0314	molybdopterin synthase activity
HBA75_RS17565	COG0303	'Molybdopterin
HBA75_RS17570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HBA75_RS17575	COG2116	formate transmembrane transporter activity
HBA75_RS17585	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HBA75_RS17590	COG5609	conserved protein (DUF2294)
HBA75_RS17595	COG2427	Protein of unknown function (DUF1641)
HBA75_RS17600	COG3383	formate dehydrogenase (NAD+) activity
HBA75_RS17605	COG0697	spore germination
HBA75_RS17620	COG0531	amino acid
HBA75_RS17655	COG2226	methyltransferase
HBA75_RS17660	COG4166	transmembrane transport
HBA75_RS17665	COG4166	transmembrane transport
HBA75_RS17670	COG4166	transmembrane transport
HBA75_RS17675	COG1301	dicarboxylic acid transport
HBA75_RS17680	COG1316	TRANSCRIPTIONal
HBA75_RS17690	COG1595	DNA-templated transcription, initiation
HBA75_RS17705	COG1131	(ABC) transporter
HBA75_RS17715	COG0673	inositol 2-dehydrogenase activity
HBA75_RS17720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBA75_RS17725	COG0187	DNA topoisomerase II activity
HBA75_RS17730	COG1832	CoA-binding protein
HBA75_RS17735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBA75_RS17740	COG0745	RESPONSE REGULATOR receiver
HBA75_RS17760	COG4841	protein insertion into membrane
HBA75_RS17770	COG0824	Thioesterase
HBA75_RS17800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HBA75_RS17810	COG1132	(ABC) transporter
HBA75_RS17815	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HBA75_RS17845	COG2211	Major facilitator Superfamily
HBA75_RS17855	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HBA75_RS17870	COG0183	Belongs to the thiolase family
HBA75_RS17875	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_RS17880	COG1268	BioY protein
HBA75_RS17885	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_RS17930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_RS17940	COG5002	protein histidine kinase activity
HBA75_RS17945	COG0400	carboxylic ester hydrolase activity
HBA75_RS17950	COG0346	lactoylglutathione lyase activity
HBA75_RS17955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBA75_RS17965	COG0069	glutamate synthase activity
HBA75_RS17975	COG3344	reverse transcriptase
HBA75_RS17985	COG1329	Transcriptional regulator
HBA75_RS17990	COG0010	Belongs to the arginase family
HBA75_RS18040	COG4846	Membrane protein involved in cytochrome C biogenesis
HBA75_RS18045	COG0785	Cytochrome C biogenesis protein
HBA75_RS18055	COG1473	amidohydrolase
HBA75_RS18080	COG0583	DNA-binding transcription factor activity
HBA75_RS18090	COG1346	cytolysis
HBA75_RS18105	COG0730	response to heat
HBA75_RS18130	COG1132	(ABC) transporter
HBA75_RS18135	COG1132	(ABC) transporter
HBA75_RS18160	COG3639	organic phosphonate transmembrane transporter activity
HBA75_RS18185	COG0737	Belongs to the 5'-nucleotidase family
HBA75_RS18195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HBA75_RS18215	COG1695	Transcriptional regulator
HBA75_RS18225	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS18225	COG1388	LysM domain
HBA75_RS18225	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_RS18230	COG0739	heme binding
HBA75_RS18235	COG0741	lytic transglycosylase activity
HBA75_RS18265	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBA75_RS18270	COG0174	glutamine synthetase
HBA75_RS18275	COG0789	Transcriptional regulator
HBA75_RS18280	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HBA75_RS18285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBA75_RS18290	COG2860	membrane
HBA75_RS18300	COG0464	growth
HBA75_RS18335	COG1388	LysM domain
HBA75_RS18335	COG3584	3D domain protein
HBA75_RS18340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBA75_RS18340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBA75_RS18340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBA75_RS18345	COG1105	Belongs to the carbohydrate kinase PfkB family
HBA75_RS18350	COG1349	DNA-binding transcription factor activity
HBA75_RS18355	COG1979	alcohol dehydrogenase
HBA75_RS18360	COG2322	membrane
HBA75_RS18370	COG1113	amino acid transport
HBA75_RS18380	COG1408	metallophosphoesterase
HBA75_RS18385	COG2116	formate transmembrane transporter activity
HBA75_RS18400	COG2217	Heavy metal translocating P-type atpase
HBA75_RS18405	COG2608	mercury ion transmembrane transporter activity
HBA75_RS18410	COG1937	Protein conserved in bacteria
HBA75_RS18420	COG2819	hydrolase of the alpha beta superfamily
HBA75_RS18425	COG1120	ATPase activity
HBA75_RS18430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_RS18435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_RS18440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_RS18450	COG2169	Transcriptional regulator
HBA75_RS18455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBA75_RS18460	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HBA75_RS18480	COG2267	carboxylic ester hydrolase activity
HBA75_RS18485	COG3300	MHYT domain
HBA75_RS18485	COG5001	Diguanylate cyclase
HBA75_RS18525	COG1346	cytolysis
HBA75_RS18535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_RS18545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HBA75_RS18560	COG1404	Belongs to the peptidase S8 family
HBA75_RS18565	COG3773	Cell wall hydrolase
HBA75_RS18575	COG1368	sulfuric ester hydrolase activity
HBA75_RS18580	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HBA75_RS18605	COG4550	Control of competence regulator ComK, YlbF/YmcA
HBA75_RS18615	COG1013	pyruvate-flavodoxin oxidoreductase activity
HBA75_RS18620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HBA75_RS18620	COG0674	pyruvate-flavodoxin oxidoreductase activity
HBA75_RS18630	COG2359	stage V sporulation protein S
HBA75_RS18635	COG1692	metallophosphoesterase
HBA75_RS18655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBA75_RS18660	COG1426	Protein conserved in bacteria
HBA75_RS18675	COG0300	oxidoreductase activity
HBA75_RS18680	COG0612	Peptidase, M16
HBA75_RS18685	COG0612	Peptidase, M16
HBA75_RS18710	COG2188	Transcriptional regulator
HBA75_RS18730	COG0740	serine-type endopeptidase activity
HBA75_RS18735	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBA75_RS18745	COG0527	aspartate kinase activity
HBA75_RS18750	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HBA75_RS18755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBA75_RS18760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBA75_RS18765	COG1873	PFAM PRC-barrel domain
HBA75_RS18770	COG0612	Peptidase, M16
HBA75_RS18775	COG0726	polysaccharide deacetylase
HBA75_RS18790	COG0196	riboflavin kinase activity
HBA75_RS18800	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HBA75_RS18805	COG1550	Protein conserved in bacteria
HBA75_RS18815	COG1358	cellular component organization or biogenesis
HBA75_RS18820	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HBA75_RS18825	COG0195	Participates in both transcription termination and antitermination
HBA75_RS18845	COG0750	zinc metalloprotease
HBA75_RS18855	COG4589	Belongs to the CDS family
HBA75_RS18900	COG4974	Belongs to the 'phage' integrase family
HBA75_RS18910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HBA75_RS18915	COG0758	DNA mediated transformation
HBA75_RS18920	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HBA75_RS18960	COG1837	Belongs to the UPF0109 family
HBA75_RS18970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HBA75_RS18980	COG0552	protein localization to endoplasmic reticulum
HBA75_RS18985	COG1196	nuclear chromosome segregation
HBA75_RS18995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBA75_RS19000	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS19005	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HBA75_RS19020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HBA75_RS19025	COG1461	Dihydroxyacetone kinase
HBA75_RS19030	COG1302	Protein conserved in bacteria
HBA75_RS19045	COG1564	THIamine pyrophosphokinase
HBA75_RS19050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HBA75_RS19060	COG2815	serine threonine protein kinase
HBA75_RS19060	COG0515	serine threonine protein kinase
HBA75_RS19065	COG0631	protein serine/threonine phosphatase activity
HBA75_RS19075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HBA75_RS19075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HBA75_RS19090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBA75_RS19095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBA75_RS19115	COG1561	YicC-like family, N-terminal region
HBA75_RS19120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HBA75_RS19130	COG0006	proline dipeptidase activity
HBA75_RS19145	COG3069	C4-dicarboxylate transmembrane transporter activity
HBA75_RS19205	COG0564	pseudouridine synthase activity
HBA75_RS19225	COG3599	regulation of cell shape
HBA75_RS19230	COG2302	S4 RNA-binding domain
HBA75_RS19235	COG0762	integral membrane protein
HBA75_RS19245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HBA75_RS19255	COG1873	PFAM PRC-barrel domain
HBA75_RS19260	COG1191	sigma factor activity
HBA75_RS19265	COG1191	sigma factor activity
HBA75_RS19275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HBA75_RS19280	COG0849	cell division
HBA75_RS19300	COG0772	Belongs to the SEDS family
HBA75_RS19320	COG0768	penicillin binding
HBA75_RS19345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBA75_RS19360	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HBA75_RS19365	COG1399	metal-binding, possibly nucleic acid-binding protein
HBA75_RS19375	COG3480	Lon protease (S16) C-terminal proteolytic domain
HBA75_RS19380	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBA75_RS19385	COG3314	Sporulation integral membrane protein YlbJ
HBA75_RS19395	COG0742	ribosomal rna small subunit methyltransferase
HBA75_RS19410	COG3679	Belongs to the UPF0342 family
HBA75_RS19415	COG0406	alpha-ribazole phosphatase activity
HBA75_RS19430	COG2340	Cysteine-rich secretory protein family
HBA75_RS19445	COG3336	cytochrome c oxidase
HBA75_RS19480	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HBA75_RS19485	COG0772	Belongs to the SEDS family
HBA75_RS19495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HBA75_RS19500	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HBA75_RS19510	COG4896	Protein conserved in bacteria
HBA75_RS19535	COG0483	inositol monophosphate 1-phosphatase activity
HBA75_RS19555	COG1982	Orn Lys Arg decarboxylase major
HBA75_RS19605	COG0022	dehydrogenase e1 component
HBA75_RS19610	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HBA75_RS19625	COG0561	phosphatase activity
HBA75_RS19635	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBA75_RS19640	COG0569	domain protein
HBA75_RS19660	COG0583	DNA-binding transcription factor activity
HBA75_RS19665	COG0517	IMP dehydrogenase activity
HBA75_RS19675	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
HBA75_RS19685	COG4703	Protein of unknown function (DUF1797)
HBA75_RS19700	COG2200	EAL domain
HBA75_RS19705	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS19710	COG1408	metallophosphoesterase
HBA75_RS19755	COG2814	Major facilitator Superfamily
HBA75_RS19775	COG3209	COG3209 Rhs family protein
HBA75_RS19785	COG2205	protein histidine kinase activity
HBA75_RS19795	COG0436	Aminotransferase
HBA75_RS19800	COG1609	Transcriptional regulator
HBA75_RS19805	COG3833	ABC-type maltose transport systems, permease component
HBA75_RS19810	COG1175	transmembrane transport
HBA75_RS19815	COG2182	Extracellular solute-binding protein
HBA75_RS19825	COG0366	Alpha amylase catalytic
HBA75_RS19830	COG3842	ATPase activity
HBA75_RS19875	COG0183	Belongs to the thiolase family
HBA75_RS19910	COG1695	Transcriptional regulator
HBA75_RS19915	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS19945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBA75_RS19950	COG0436	Aminotransferase
HBA75_RS19985	COG2084	Dehydrogenase
HBA75_RS19995	COG2199	diguanylate cyclase activity
HBA75_RS19995	COG2203	Gaf domain
HBA75_RS20000	COG0778	Nitroreductase
HBA75_RS20025	COG2190	(PTS) system
HBA75_RS20025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBA75_RS20025	COG1263	PTS System
HBA75_RS20030	COG3711	transcriptional antiterminator
HBA75_RS20040	COG2188	Transcriptional regulator
HBA75_RS20050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HBA75_RS20075	COG1547	Domain of unknown function (DUF309)
HBA75_RS20080	COG0456	acetyltransferase
HBA75_RS20085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HBA75_RS20090	COG4086	secreted protein
HBA75_RS20095	COG2801	Transposase and inactivated derivatives
HBA75_RS20105	COG0561	phosphatase activity
HBA75_RS20110	COG0697	spore germination
HBA75_RS20160	COG0733	neurotransmitter:sodium symporter activity
HBA75_RS20180	COG1686	Belongs to the peptidase S11 family
HBA75_RS20185	COG1725	Transcriptional regulator
HBA75_RS20190	COG1131	(ABC) transporter
HBA75_RS20210	COG1846	Transcriptional regulator
HBA75_RS20225	COG0598	Magnesium transport protein CorA
HBA75_RS20250	COG4974	Belongs to the 'phage' integrase family
HBA75_RS20260	COG0735	belongs to the Fur family
HBA75_RS20265	COG1300	Membrane
HBA75_RS20285	COG0667	Aldo Keto reductase
HBA75_RS20290	COG0656	L-ascorbic acid biosynthetic process
HBA75_RS20295	COG0456	acetyltransferase
HBA75_RS20295	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBA75_RS20305	COG4085	toxin activity
HBA75_RS20305	COG0737	Belongs to the 5'-nucleotidase family
HBA75_RS20305	COG1525	nuclease
HBA75_RS20315	COG0596	Alpha beta hydrolase
HBA75_RS20320	COG2056	Na+-H+ antiporter family
HBA75_RS20325	COG1609	Transcriptional regulator
HBA75_RS20330	COG0456	acetyltransferase
HBA75_RS20335	COG1073	alpha beta
HBA75_RS20350	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBA75_RS20350	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBA75_RS20355	COG0307	riboflavin synthase, alpha
HBA75_RS20385	COG1073	alpha beta
HBA75_RS20385	COG2226	methyltransferase
HBA75_RS20400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HBA75_RS20415	COG0737	Belongs to the 5'-nucleotidase family
HBA75_RS20425	COG1522	sequence-specific DNA binding
HBA75_RS20470	COG0300	oxidoreductase activity
HBA75_RS20475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_RS20480	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBA75_RS20485	COG1760	l-serine dehydratase
HBA75_RS20490	COG1760	l-serine dehydratase
HBA75_RS20525	COG1285	pathogenesis
HBA75_RS20535	COG2195	Cleaves the N-terminal amino acid of tripeptides
HBA75_RS20540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_RS20555	COG1376	ErfK ybiS ycfS ynhG family protein
HBA75_RS20560	COG4129	membrane
HBA75_RS20565	COG1126	abc transporter atp-binding protein
HBA75_RS20570	COG0765	amino acid transport
HBA75_RS20575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBA75_RS20590	COG2816	NAD+ diphosphatase activity
HBA75_RS20595	COG2323	membrane
HBA75_RS20600	COG0772	Belongs to the SEDS family
HBA75_RS20605	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBA75_RS20610	COG0022	dehydrogenase e1 component
HBA75_RS20615	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HBA75_RS20620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBA75_RS20635	COG0280	phosphate acetyltransferase
HBA75_RS20640	COG3290	protein histidine kinase activity
HBA75_RS20640	COG3829	transcription factor binding
HBA75_RS20650	COG0584	glycerophosphoryl diester phosphodiesterase
HBA75_RS20655	COG3093	addiction module antidote protein HigA
HBA75_RS20675	COG0750	zinc metalloprotease
HBA75_RS20680	COG0497	DNA recombination
HBA75_RS20705	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HBA75_RS20715	COG0142	geranyltranstransferase activity
HBA75_RS20740	COG1302	Protein conserved in bacteria
HBA75_RS20745	COG0439	Biotin carboxylase
HBA75_RS20750	COG0511	ligase activity, forming carbon-carbon bonds
HBA75_RS20795	COG3854	ATPases associated with a variety of cellular activities
HBA75_RS20820	COG0006	proline dipeptidase activity
HBA75_RS20840	COG3872	metal-dependent enzyme
HBA75_RS20850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HBA75_RS20865	COG1695	Transcriptional regulator
HBA75_RS20885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_RS20895	COG1609	Transcriptional regulator
HBA75_RS20905	COG2076	Multidrug Resistance protein
HBA75_RS20910	COG2076	Multidrug Resistance protein
HBA75_RS20945	COG1725	Transcriptional regulator
HBA75_RS20975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HBA75_RS21040	COG1459	type II secretion system
HBA75_RS21045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HBA75_RS21100	COG0646	methionine synthase
HBA75_RS21100	COG1410	methionine synthase
HBA75_RS21105	COG0646	methionine synthase
HBA75_RS21105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HBA75_RS21110	COG0626	cystathionine gamma-synthase activity
HBA75_RS21115	COG0626	cystathionine gamma-synthase activity
HBA75_RS21140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_RS21150	COG1940	carbohydrate kinase activity
HBA75_RS21155	COG4483	Protein conserved in bacteria
HBA75_RS21160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HBA75_RS21165	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HBA75_RS21170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HBA75_RS21175	COG0704	Plays a role in the regulation of phosphate uptake
HBA75_RS21185	COG0573	inorganic phosphate transmembrane transporter activity
HBA75_RS21190	COG0573	inorganic phosphate transmembrane transporter activity
HBA75_RS21195	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HBA75_RS21205	COG0477	Major facilitator Superfamily
HBA75_RS21210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HBA75_RS21220	COG5521	maltodextrose utilization protein MalA
HBA75_RS21235	COG0735	belongs to the Fur family
HBA75_RS21240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HBA75_RS21245	COG1121	(ABC) transporter
HBA75_RS21250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_RS21280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HBA75_RS21285	COG2384	SAM-dependent methyltransferase
HBA75_RS21295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBA75_RS21300	COG0358	DNA primase activity
HBA75_RS21315	COG0517	IMP dehydrogenase activity
HBA75_RS21330	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HBA75_RS21335	COG0295	cytidine deaminase activity
HBA75_RS21340	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HBA75_RS21350	COG1480	7TM receptor with intracellular HD hydrolase
HBA75_RS21355	COG1702	phosphate starvation-inducible protein PhoH
HBA75_RS21375	COG1610	YqeY-like protein
HBA75_RS21380	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HBA75_RS21385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HBA75_RS21390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HBA75_RS21420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HBA75_RS21425	COG1733	regulation of RNA biosynthetic process
HBA75_RS21435	COG2801	Transposase and inactivated derivatives
HBA75_RS21460	COG1466	dna polymerase III delta subunit
HBA75_RS21475	COG2131	deaminase
HBA75_RS21480	COG1596	polysaccharide export
HBA75_RS21480	COG1555	photosystem II stabilization
HBA75_RS21485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBA75_RS21490	COG2226	methyltransferase
HBA75_RS21495	COG0799	negative regulation of ribosome biogenesis
HBA75_RS21500	COG1713	HD superfamily hydrolase involved in NAD metabolism
HBA75_RS21510	COG1534	Rna-binding protein
HBA75_RS21520	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HBA75_RS21525	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HBA75_RS21560	COG0778	Nitroreductase
HBA75_RS21565	COG2357	RelA SpoT domain protein
HBA75_RS21575	COG1785	Belongs to the alkaline phosphatase family
HBA75_RS21585	COG2267	carboxylic ester hydrolase activity
HBA75_RS21620	COG1404	Belongs to the peptidase S8 family
HBA75_RS21635	COG2514	catechol 2,3-dioxygenase activity
HBA75_RS21640	COG2259	Doxx family
HBA75_RS21680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_RS21690	COG1454	alcohol dehydrogenase
HBA75_RS21690	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_RS21695	COG0626	cystathionine gamma-synthase activity
HBA75_RS21700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HBA75_RS21755	COG4122	O-methyltransferase activity
HBA75_RS21760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HBA75_RS21790	COG0628	permease
HBA75_RS21810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HBA75_RS21825	COG1104	cysteine desulfurase activity
HBA75_RS21830	COG1959	2 iron, 2 sulfur cluster binding
HBA75_RS21835	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HBA75_RS21845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HBA75_RS21870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBA75_RS21880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HBA75_RS21880	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HBA75_RS21885	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBA75_RS21890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HBA75_RS21890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HBA75_RS21900	COG2244	polysaccharide biosynthetic process
HBA75_RS21905	COG2323	membrane
HBA75_RS21920	COG1862	Preprotein translocase
HBA75_RS21950	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HBA75_RS21985	COG0157	Belongs to the NadC ModD family
HBA75_RS21990	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HBA75_RS21995	COG1104	cysteine desulfurase activity
HBA75_RS22000	COG1827	regulation of RNA biosynthetic process
HBA75_RS22005	COG2258	MOSC domain
HBA75_RS22010	COG0077	Prephenate dehydratase
HBA75_RS22015	COG0577	efflux transmembrane transporter activity
HBA75_RS22020	COG0577	efflux transmembrane transporter activity
HBA75_RS22025	COG1136	(ABC) transporter
HBA75_RS22030	COG5002	protein histidine kinase activity
HBA75_RS22035	COG0745	RESPONSE REGULATOR receiver
HBA75_RS22045	COG3290	protein histidine kinase activity
HBA75_RS22055	COG2868	ribosomal protein
HBA75_RS22065	COG1530	ribonuclease E activity
HBA75_RS22070	COG1994	Peptidase M50
HBA75_RS22075	COG0739	heme binding
HBA75_RS22080	COG2894	cell division
HBA75_RS22100	COG1077	Cell shape determining protein MreB Mrl
HBA75_RS22130	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_RS22130	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS22130	COG1388	LysM domain
HBA75_RS22135	COG4824	toxin secretion phage lysis holin
HBA75_RS22255	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS22270	COG1595	DNA-templated transcription, initiation
HBA75_RS22280	COG3331	DNA recombination
HBA75_RS22375	COG3646	Phage regulatory protein
HBA75_RS22395	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HBA75_RS22415	COG0285	dihydrofolate synthase activity
HBA75_RS22430	COG1388	LysM domain
HBA75_RS22440	COG0113	porphobilinogen synthase activity
HBA75_RS22445	COG1587	Uroporphyrinogen-III synthase
HBA75_RS22455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HBA75_RS22465	COG1846	Transcriptional regulator
HBA75_RS22475	COG1764	response to oxidative stress
HBA75_RS22490	COG1067	ATP-dependent peptidase activity
HBA75_RS22490	COG0470	DNA polymerase III
HBA75_RS22535	COG0622	Phosphoesterase
HBA75_RS22550	COG5401	PFAM Sporulation and spore germination
HBA75_RS22570	COG1309	transcriptional regulator
HBA75_RS22580	COG2197	response regulator
HBA75_RS22585	COG2233	PERMEase
HBA75_RS22590	COG0402	S-adenosylhomocysteine deaminase activity
HBA75_RS22595	COG1983	PspC domain protein
HBA75_RS22600	COG1396	sequence-specific DNA binding
HBA75_RS22605	COG0697	spore germination
HBA75_RS22615	COG1959	2 iron, 2 sulfur cluster binding
HBA75_RS22620	COG1668	transmembrane transport
HBA75_RS22625	COG4152	abc transporter atp-binding protein
HBA75_RS22630	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HBA75_RS22635	COG1360	Flagellar Motor Protein
HBA75_RS22640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HBA75_RS22645	COG1876	peptidase activity
HBA75_RS22650	COG0824	Thioesterase
HBA75_RS22655	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HBA75_RS22660	COG1053	succinate dehydrogenase
HBA75_RS22665	COG2009	succinate dehydrogenase
HBA75_RS22670	COG1719	4-vinyl reductase, 4VR
HBA75_RS22680	COG3118	belongs to the thioredoxin family
HBA75_RS22685	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HBA75_RS22690	COG2086	electron transfer activity
HBA75_RS22695	COG1024	Enoyl-CoA hydratase
HBA75_RS22700	COG1309	transcriptional regulator
HBA75_RS22705	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_RS22735	COG2318	DinB family
HBA75_RS22760	COG1131	(ABC) transporter
HBA75_RS22765	COG2205	protein histidine kinase activity
HBA75_RS22770	COG0745	RESPONSE REGULATOR receiver
HBA75_RS22780	COG4895	conserved protein (DUF2196)
HBA75_RS22785	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HBA75_RS22795	COG4509	Sortase family
HBA75_RS22800	COG1120	ATPase activity
HBA75_RS22815	COG5386	Cell surface protein
HBA75_RS22825	COG5386	Cell surface protein
HBA75_RS22830	COG1114	Component of the transport system for branched-chain amino acids
HBA75_RS22835	COG1187	pseudouridine synthase activity
HBA75_RS22845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HBA75_RS22845	COG1796	DNA polymerase
HBA75_RS22850	COG1286	toxin biosynthetic process
HBA75_RS22890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBA75_RS22900	COG1418	mRNA catabolic process
HBA75_RS22915	COG2814	Major facilitator Superfamily
HBA75_RS22920	COG1566	PFAM secretion protein HlyD family protein
HBA75_RS22925	COG1309	transcriptional regulator
HBA75_RS22930	COG1363	Peptidase, m42
HBA75_RS22955	COG2801	Transposase and inactivated derivatives
HBA75_RS22965	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HBA75_RS22980	COG1484	DNA-dependent DNA replication
HBA75_RS22985	COG3611	Membrane attachment protein
HBA75_RS22995	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HBA75_RS23000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HBA75_RS23010	COG1971	Probably functions as a manganese efflux pump
HBA75_RS23020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HBA75_RS23020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HBA75_RS23025	COG5002	protein histidine kinase activity
HBA75_RS23030	COG0745	RESPONSE REGULATOR receiver
HBA75_RS23045	COG0538	isocitrate dehydrogenase activity
HBA75_RS23050	COG0372	Belongs to the citrate synthase family
HBA75_RS23060	COG0628	permease
HBA75_RS23065	COG3030	protein affecting phage T7 exclusion by the F plasmid
HBA75_RS23090	COG1725	Transcriptional regulator
HBA75_RS23095	COG0281	malic enzyme
HBA75_RS23100	COG0587	DNA-directed DNA polymerase activity
HBA75_RS23115	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HBA75_RS23130	COG4109	DRTGG domain
HBA75_RS23145	COG0006	proline dipeptidase activity
HBA75_RS23170	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS23180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_RS23185	COG0662	Cupin 2, conserved barrel domain protein
HBA75_RS23200	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS23205	COG0589	response to stress
HBA75_RS23245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_RS23270	COG0827	DNA restriction-modification system
HBA75_RS23275	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HBA75_RS23280	COG3874	Sporulation protein YtfJ
HBA75_RS23295	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HBA75_RS23305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBA75_RS23320	COG1104	cysteine desulfurase activity
HBA75_RS23345	COG0697	spore germination
HBA75_RS23350	COG1309	transcriptional regulator
HBA75_RS23355	COG1956	GAF domain-containing protein
HBA75_RS23360	COG0626	cystathionine gamma-synthase activity
HBA75_RS23390	COG0110	maltose O-acetyltransferase activity
HBA75_RS23395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBA75_RS23400	COG0454	-acetyltransferase
HBA75_RS23405	COG0517	IMP dehydrogenase activity
HBA75_RS23410	COG0123	including yeast histone deacetylase and acetoin utilization protein
HBA75_RS23425	COG0745	RESPONSE REGULATOR receiver
HBA75_RS23435	COG0666	response to abiotic stimulus
HBA75_RS23470	COG1609	Transcriptional regulator
HBA75_RS23475	COG1605	Chorismate mutase
HBA75_RS23475	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HBA75_RS23480	COG4851	CamS sex pheromone cAM373 precursor
HBA75_RS23485	COG3118	belongs to the thioredoxin family
HBA75_RS23495	COG2309	aminopeptidase activity
HBA75_RS23510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_RS23525	COG1674	ftsk spoiiie
HBA75_RS23530	COG0860	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS23530	COG1388	LysM domain
HBA75_RS23540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBA75_RS23550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HBA75_RS23555	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HBA75_RS23560	COG1363	Peptidase, m42
HBA75_RS23570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_RS23590	COG0510	thiamine kinase activity
HBA75_RS23600	COG1523	belongs to the glycosyl hydrolase 13 family
HBA75_RS23610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HBA75_RS23615	COG1349	DNA-binding transcription factor activity
HBA75_RS23620	COG1187	pseudouridine synthase activity
HBA75_RS23625	COG2244	polysaccharide biosynthetic process
HBA75_RS23630	COG2081	HI0933 family
HBA75_RS23655	COG3832	glyoxalase III activity
HBA75_RS23675	COG1329	Transcriptional regulator
HBA75_RS23700	COG0314	molybdopterin synthase activity
HBA75_RS23705	COG1763	Mo-molybdopterin cofactor biosynthetic process
HBA75_RS23710	COG0303	'Molybdopterin
HBA75_RS23720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HBA75_RS23725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBA75_RS23745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_RS23755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBA75_RS23805	COG0475	glutathione-regulated potassium exporter activity
HBA75_RS23810	COG0490	domain, Protein
HBA75_RS23815	COG0582	viral genome integration into host DNA
HBA75_RS23825	COG1136	(ABC) transporter
HBA75_RS23845	COG1242	4 iron, 4 sulfur cluster binding
HBA75_RS23850	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HBA75_RS23855	COG1794	racemase activity, acting on amino acids and derivatives
HBA75_RS23870	COG2267	carboxylic ester hydrolase activity
HBA75_RS23875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HBA75_RS23880	COG0671	phosphoesterase, PA-phosphatase related
HBA75_RS23885	COG0438	transferase activity, transferring glycosyl groups
HBA75_RS23905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_RS23950	COG5002	protein histidine kinase activity
HBA75_RS23955	COG3852	Histidine kinase
HBA75_RS23970	COG2267	carboxylic ester hydrolase activity
HBA75_RS23975	COG1368	sulfuric ester hydrolase activity
HBA75_RS24000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBA75_RS24005	COG1116	anion transmembrane transporter activity
HBA75_RS24010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBA75_RS24035	COG2801	Transposase and inactivated derivatives
HBA75_RS24050	COG0494	nUDIX hydrolase
HBA75_RS24080	COG1854	S-ribosylhomocysteine lyase activity
HBA75_RS24090	COG0288	reversible hydration of carbon dioxide
HBA75_RS24095	COG1271	oxidase subunit
HBA75_RS24100	COG1294	oxidase, subunit
HBA75_RS24115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_RS24140	COG1842	Phage shock protein A
HBA75_RS24170	COG5002	protein histidine kinase activity
HBA75_RS24175	COG0745	RESPONSE REGULATOR receiver
HBA75_RS24205	COG1597	lipid kinase activity
HBA75_RS24225	COG3344	reverse transcriptase
HBA75_RS24270	COG0586	Pfam SNARE associated Golgi protein
HBA75_RS24280	COG0577	efflux transmembrane transporter activity
HBA75_RS24285	COG1136	(ABC) transporter
HBA75_RS24290	COG2207	Transcriptional regulator
HBA75_RS24290	COG3708	Transcriptional regulator
HBA75_RS24310	COG5658	integral membrane protein
HBA75_RS24315	COG0640	Transcriptional regulator
HBA75_RS24320	COG0745	RESPONSE REGULATOR receiver
HBA75_RS24325	COG2205	protein histidine kinase activity
HBA75_RS24330	COG0577	efflux transmembrane transporter activity
HBA75_RS24335	COG0577	efflux transmembrane transporter activity
HBA75_RS24340	COG1136	(ABC) transporter
HBA75_RS24345	COG0577	efflux transmembrane transporter activity
HBA75_RS24370	COG2188	Transcriptional regulator
HBA75_RS24390	COG3964	amidohydrolase
HBA75_RS24410	COG4948	Mandelate Racemase Muconate Lactonizing
HBA75_RS24420	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HBA75_RS24425	COG0596	Alpha beta hydrolase
HBA75_RS24435	COG1169	isochorismate synthase
HBA75_RS24440	COG1575	Belongs to the MenA family. Type 1 subfamily
HBA75_RS24445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HBA75_RS24470	COG0058	SHG alpha-glucan phosphorylase activity
HBA75_RS24480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HBA75_RS24500	COG1404	Belongs to the peptidase S8 family
HBA75_RS24600	COG0544	peptidyl-prolyl cis-trans isomerase activity
HBA75_RS24635	COG1285	pathogenesis
HBA75_RS24640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBA75_RS24655	COG2155	Conserved Protein
HBA75_RS24660	COG1098	S1 RNA binding domain
HBA75_RS24665	COG0436	Aminotransferase
HBA75_RS24670	COG1522	sequence-specific DNA binding
HBA75_RS24675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBA75_RS24680	COG2267	carboxylic ester hydrolase activity
HBA75_RS24690	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HBA75_RS24710	COG5018	Exonuclease
HBA75_RS24715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HBA75_RS24735	COG2050	protein possibly involved in aromatic compounds catabolism
HBA75_RS24745	COG1268	BioY protein
HBA75_RS24750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HBA75_RS24755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBA75_RS24775	COG2076	Multidrug Resistance protein
HBA75_RS24780	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HBA75_RS24790	COG3584	3D domain protein
HBA75_RS24805	COG1252	NADH dehydrogenase
HBA75_RS24820	COG3708	Transcriptional regulator
HBA75_RS24835	COG1683	Conserved Protein
HBA75_RS24890	COG4824	toxin secretion phage lysis holin
HBA75_RS25030	COG1191	sigma factor activity
HBA75_RS25055	COG3645	SOS response
HBA75_RS25055	COG3646	Phage regulatory protein
HBA75_RS25075	COG1396	sequence-specific DNA binding
HBA75_RS25115	COG0316	Belongs to the HesB IscA family
HBA75_RS25130	COG1252	NADH dehydrogenase
HBA75_RS25140	COG2274	protein secretion by the type I secretion system
HBA75_RS25145	COG0390	transport system, permease component
HBA75_RS25150	COG2824	Alkylphosphonate utilization operon protein PhnA
HBA75_RS25195	COG3344	reverse transcriptase
HBA75_RS25225	COG4837	Protein of unknown function (DUF1462)
HBA75_RS25230	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HBA75_RS25240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HBA75_RS25245	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HBA75_RS25265	COG1358	cellular component organization or biogenesis
HBA75_RS25275	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBA75_RS25285	COG0647	UMP catabolic process
HBA75_RS25295	COG2445	Protein of unknown function DUF86
HBA75_RS25300	COG1494	fructose-1,6-bisphosphatase
HBA75_RS25320	COG4470	Protein conserved in bacteria
HBA75_RS25330	COG0789	Transcriptional regulator
HBA75_RS25335	COG4377	Putative membrane peptidase family (DUF2324)
HBA75_RS25360	COG0739	heme binding
HBA75_RS25370	COG3377	Domain of unknown function (DUF1805)
HBA75_RS25375	COG0737	Belongs to the 5'-nucleotidase family
HBA75_RS25380	COG0719	Fe-S assembly protein
HBA75_RS25385	COG0822	iron-sulfur transferase activity
HBA75_RS25390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HBA75_RS25395	COG0719	Fe-S assembly protein
HBA75_RS25400	COG0396	ATPase activity
HBA75_RS25405	COG1464	Belongs to the NlpA lipoprotein family
HBA75_RS25410	COG1464	Belongs to the NlpA lipoprotein family
HBA75_RS25415	COG2011	ABC-type metal ion transport system permease component
HBA75_RS25430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HBA75_RS25435	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HBA75_RS25445	COG1393	Belongs to the ArsC family
HBA75_RS25485	COG1309	transcriptional regulator
HBA75_RS25490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_RS25495	COG1960	acyl-CoA dehydrogenase activity
HBA75_RS25500	COG0183	Belongs to the thiolase family
HBA75_RS25505	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBA75_RS25505	COG1024	Enoyl-CoA hydratase
HBA75_RS25515	COG1686	Belongs to the peptidase S11 family
HBA75_RS25530	COG0011	TIGRFAM Protein of
HBA75_RS25535	COG0840	transmembrane signaling receptor activity
HBA75_RS25550	COG2814	Major facilitator Superfamily
HBA75_RS25555	COG0531	amino acid
HBA75_RS25580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_RS25615	COG0586	Pfam SNARE associated Golgi protein
HBA75_RS25625	COG1376	ErfK ybiS ycfS ynhG family protein
HBA75_RS25630	COG0745	RESPONSE REGULATOR receiver
HBA75_RS25635	COG5002	protein histidine kinase activity
HBA75_RS25685	COG0840	transmembrane signaling receptor activity
HBA75_RS25690	COG2151	metal-sulfur cluster biosynthetic enzyme
HBA75_RS25695	COG3227	Zinc metalloprotease (Elastase)
HBA75_RS25715	COG0586	Pfam SNARE associated Golgi protein
HBA75_RS25720	COG0475	glutathione-regulated potassium exporter activity
HBA75_RS25725	COG0490	domain, Protein
HBA75_RS25730	COG1115	amino acid carrier protein
HBA75_RS25735	COG0783	Belongs to the Dps family
HBA75_RS25750	COG1611	Belongs to the LOG family
HBA75_RS25760	COG1528	Iron-storage protein
HBA75_RS25770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_RS25775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_RS25780	COG1115	amino acid carrier protein
HBA75_RS25785	COG1115	amino acid carrier protein
HBA75_RS25790	COG2910	NAD(P)H-binding
HBA75_RS25805	COG0656	L-ascorbic acid biosynthetic process
HBA75_RS25810	COG2814	Major facilitator Superfamily
HBA75_RS25815	COG1733	regulation of RNA biosynthetic process
HBA75_RS25825	COG1252	NADH dehydrogenase
HBA75_RS25875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_RS25890	COG1335	isochorismatase
HBA75_RS25895	COG1522	sequence-specific DNA binding
HBA75_RS25960	COG0557	exoribonuclease II activity
HBA75_RS25965	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS25990	COG1674	ftsk spoiiie
HBA75_RS26015	COG4824	toxin secretion phage lysis holin
HBA75_RS26025	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS26100	COG5484	DNA packaging
HBA75_RS26125	COG0582	viral genome integration into host DNA
HBA75_RS26225	COG3646	Phage regulatory protein
HBA75_RS26245	COG1396	sequence-specific DNA binding
HBA75_RS26255	COG0582	viral genome integration into host DNA
HBA75_RS26260	COG1647	Serine aminopeptidase, S33
HBA75_RS26265	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HBA75_RS26270	COG1346	cytolysis
HBA75_RS26305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HBA75_RS26320	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HBA75_RS26345	COG1388	LysM domain
HBA75_RS26345	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_RS26345	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS26350	COG4824	toxin secretion phage lysis holin
HBA75_RS26425	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS26485	COG1595	DNA-templated transcription, initiation
HBA75_RS26495	COG3331	DNA recombination
HBA75_RS26600	COG3646	Phage regulatory protein
HBA75_RS26630	COG0582	viral genome integration into host DNA
HBA75_RS26680	COG0582	viral genome integration into host DNA
HBA75_RS26685	COG1555	photosystem II stabilization
HBA75_RS26685	COG1596	polysaccharide export
HBA75_RS26715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HBA75_RS26730	COG2323	membrane
HBA75_RS26740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBA75_RS26750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HBA75_RS26760	COG1051	belongs to the nudix hydrolase family
HBA75_RS26770	COG0492	ferredoxin-NADP+ reductase activity
HBA75_RS26775	COG0457	Tetratricopeptide repeat
HBA75_RS26780	COG0110	maltose O-acetyltransferase activity
HBA75_RS26800	COG1950	PFAM Membrane protein of
HBA75_RS26810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HBA75_RS26815	COG0556	nucleotide-excision repair
HBA75_RS26830	COG0789	Transcriptional regulator
HBA75_RS26850	COG0583	DNA-binding transcription factor activity
HBA75_RS26860	COG0655	NAD(P)H dehydrogenase (quinone) activity
HBA75_RS26865	COG0488	(ABC) transporter
HBA75_RS26875	COG1132	(ABC) transporter
HBA75_RS26880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBA75_RS26885	COG0793	Belongs to the peptidase S41A family
HBA75_RS26885	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_RS26890	COG2177	Part of the ABC transporter FtsEX involved in
HBA75_RS26895	COG2884	Cell division ATP-binding protein ftsE
HBA75_RS26915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HBA75_RS26920	COG1278	Cold shock
HBA75_RS26925	COG1040	competence protein
HBA75_RS26930	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HBA75_RS26935	COG3103	Sh3 type 3 domain protein
HBA75_RS26935	COG1388	LysM domain
HBA75_RS26935	COG0791	NLP P60 protein
HBA75_RS26940	COG1733	regulation of RNA biosynthetic process
HBA75_RS26945	COG1307	EDD domain protein, DegV family
HBA75_RS26950	COG1739	Uncharacterized protein family UPF0029
HBA75_RS26955	COG1316	TRANSCRIPTIONal
HBA75_RS26960	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HBA75_RS26965	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HBA75_RS26970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HBA75_RS26980	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HBA75_RS26980	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HBA75_RS27000	COG1486	melibiose metabolic process
HBA75_RS27005	COG1447	Phosphotransferase system cellobiose-specific component IIA
HBA75_RS27010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBA75_RS27030	COG1447	Phosphotransferase system cellobiose-specific component IIA
HBA75_RS27040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBA75_RS27045	COG1301	dicarboxylic acid transport
HBA75_RS27060	COG1511	domain protein
HBA75_RS27065	COG0583	DNA-binding transcription factor activity
HBA75_RS27070	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HBA75_RS27080	COG1271	oxidase subunit
HBA75_RS27085	COG1294	oxidase, subunit
HBA75_RS27090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HBA75_RS27100	COG1620	l-lactate permease
HBA75_RS27110	COG2389	metal-binding protein
HBA75_RS27120	COG1368	sulfuric ester hydrolase activity
HBA75_RS27130	COG0791	NLP P60 protein
HBA75_RS27130	COG1388	LysM domain
HBA75_RS27135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_RS27160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBA75_RS27165	COG3584	3D domain protein
HBA75_RS27165	COG1388	LysM domain
HBA75_RS27200	COG4715	Zinc finger, swim domain protein
HBA75_RS27205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HBA75_RS27215	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS27250	COG0577	efflux transmembrane transporter activity
HBA75_RS27255	COG1136	(ABC) transporter
HBA75_RS27290	COG5002	protein histidine kinase activity
HBA75_RS27295	COG0745	RESPONSE REGULATOR receiver
HBA75_RS27300	COG1482	cell wall glycoprotein biosynthetic process
HBA75_RS27305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBA75_RS27305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBA75_RS27305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBA75_RS27310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBA75_RS27310	COG3711	transcriptional antiterminator
HBA75_RS27315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBA75_RS27330	COG1482	cell wall glycoprotein biosynthetic process
HBA75_RS27360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HBA75_RS27365	COG1091	dTDP-4-dehydrorhamnose reductase activity
HBA75_RS27380	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HBA75_RS27405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HBA75_RS27410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HBA75_RS27415	COG4464	protein tyrosine phosphatase activity
HBA75_RS27420	COG0489	protein tyrosine kinase activity
HBA75_RS27425	COG3944	biosynthesis protein
HBA75_RS27430	COG0489	protein tyrosine kinase activity
HBA75_RS27445	COG1609	Transcriptional regulator
HBA75_RS27455	COG0739	heme binding
HBA75_RS27470	COG3279	Response regulator of the LytR AlgR family
HBA75_RS27475	COG2385	sporulation resulting in formation of a cellular spore
HBA75_RS27490	COG4836	Membrane
HBA75_RS27495	COG1007	ATP synthesis coupled electron transport
HBA75_RS27500	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HBA75_RS27505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HBA75_RS27515	COG0839	Belongs to the complex I subunit 6 family
HBA75_RS27535	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HBA75_RS27550	COG3300	MHYT domain
HBA75_RS27550	COG5001	Diguanylate cyclase
HBA75_RS27600	COG0356	it plays a direct role in the translocation of protons across the membrane
HBA75_RS27635	COG0698	ribose 5-phosphate isomerase
HBA75_RS27650	COG2259	Doxx family
HBA75_RS27655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBA75_RS27670	COG0009	L-threonylcarbamoyladenylate synthase
HBA75_RS27705	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HBA75_RS27710	COG1494	fructose-1,6-bisphosphatase
HBA75_RS27730	COG4821	SIS domain
HBA75_RS27740	COG3343	RNA polymerase activity
HBA75_RS27750	COG1960	acyl-CoA dehydrogenase activity
HBA75_RS27755	COG1960	acyl-CoA dehydrogenase activity
HBA75_RS27760	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBA75_RS27765	COG0183	Belongs to the thiolase family
HBA75_RS27770	COG2181	nitrate reductase activity
HBA75_RS27770	COG0247	lactate metabolic process
HBA75_RS27775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBA75_RS27790	COG3300	MHYT domain
HBA75_RS27790	COG5001	Diguanylate cyclase
HBA75_RS27805	COG3227	Zinc metalloprotease (Elastase)
HBA75_RS27810	COG2197	response regulator
HBA75_RS27815	COG4585	Histidine kinase
HBA75_RS27820	COG0842	Transport permease protein
HBA75_RS27825	COG1131	(ABC) transporter
HBA75_RS27830	COG0024	Methionine aminopeptidase
HBA75_RS27840	COG2234	aminopeptidase activity
HBA75_RS27855	COG1595	DNA-templated transcription, initiation
HBA75_RS27865	COG4506	Protein conserved in bacteria
HBA75_RS27870	COG1619	proteins homologs of microcin C7 resistance protein MccF
HBA75_RS27895	COG2814	Major facilitator Superfamily
HBA75_RS27900	COG0789	Transcriptional regulator
HBA75_RS27905	COG0584	glycerophosphoryl diester phosphodiesterase
HBA75_RS27910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBA75_RS27920	COG1994	Peptidase M50
HBA75_RS27930	COG1078	dGTPase activity
HBA75_RS27935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_RS27940	COG1120	ATPase activity
HBA75_RS27945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_RS27950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_RS27970	COG0280	phosphate acetyltransferase
HBA75_RS27985	COG3773	Cell wall hydrolase
HBA75_RS28010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBA75_RS28015	COG2233	PERMEase
HBA75_RS28020	COG0561	phosphatase activity
HBA75_RS28025	COG2814	Major facilitator Superfamily
HBA75_RS28035	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HBA75_RS28040	COG1131	(ABC) transporter
HBA75_RS28045	COG2755	lipolytic protein G-D-S-L family
HBA75_RS28050	COG1609	Transcriptional regulator
HBA75_RS28060	COG0460	homoserine dehydrogenase
HBA75_RS28070	COG2873	o-acetylhomoserine
HBA75_RS28080	COG1011	Hydrolase
HBA75_RS28085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBA75_RS28095	COG2197	response regulator
HBA75_RS28100	COG4585	Histidine kinase
HBA75_RS28100	COG2203	Gaf domain
HBA75_RS28105	COG0351	phosphomethylpyrimidine kinase
HBA75_RS28110	COG3706	GGDEF domain
HBA75_RS28115	COG2879	small protein
HBA75_RS28120	COG1966	Carbon starvation protein
HBA75_RS28125	COG3279	Response regulator of the LytR AlgR family
HBA75_RS28130	COG0477	Major facilitator Superfamily
HBA75_RS28135	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HBA75_RS28140	COG0438	transferase activity, transferring glycosyl groups
HBA75_RS28155	COG0840	transmembrane signaling receptor activity
HBA75_RS28165	COG1607	acyl-coa hydrolase
HBA75_RS28170	COG1216	Glycosyl transferase, family 2
HBA75_RS28180	COG1216	Glycosyl transferase, family 2
HBA75_RS28200	COG0463	Glycosyl transferase, family 2
HBA75_RS28205	COG0488	(ABC) transporter
HBA75_RS28210	COG1309	transcriptional regulator
HBA75_RS28215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBA75_RS28220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HBA75_RS28220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HBA75_RS28225	COG0628	permease
HBA75_RS28245	COG3275	phosphorelay sensor kinase activity
HBA75_RS28250	COG2814	Major facilitator Superfamily
HBA75_RS28255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBA75_RS28260	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HBA75_RS28280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBA75_RS28285	COG1272	protein, Hemolysin III
HBA75_RS28305	COG1164	Oligoendopeptidase f
HBA75_RS28325	COG2801	Transposase and inactivated derivatives
HBA75_RS28340	COG5002	protein histidine kinase activity
HBA75_RS28355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBA75_RS28360	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HBA75_RS28365	COG4853	Protein conserved in bacteria
HBA75_RS28375	COG5002	protein histidine kinase activity
HBA75_RS28380	COG0745	RESPONSE REGULATOR receiver
HBA75_RS28410	COG0305	Participates in initiation and elongation during chromosome replication
HBA75_RS28420	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HBA75_RS28425	COG4241	membrane
HBA75_RS28445	COG0012	GTP binding
HBA75_RS28450	COG4481	Protein conserved in bacteria
HBA75_RS28455	COG0668	transmembrane transport
HBA75_RS28465	COG1475	DNA binding
HBA75_RS28470	COG1192	Involved in chromosome partitioning
HBA75_RS28495	COG1847	R3H domain protein
HBA75_RS28510	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HBA75_RS28515	COG3321	synthase
HBA75_RS28515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBA75_RS28515	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_RS28515	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS28515	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS28515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBA75_RS28515	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_RS28515	COG0300	oxidoreductase activity
HBA75_RS28515	COG3321	synthase
HBA75_RS28515	COG0300	oxidoreductase activity
HBA75_RS28535	COG1960	acyl-CoA dehydrogenase activity
HBA75_RS28550	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBA75_RS28555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBA75_RS28560	COG1960	acyl-CoA dehydrogenase activity
HBA75_RS28570	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_RS28570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBA75_RS28570	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_RS28570	COG3321	synthase
HBA75_RS28570	COG0300	oxidoreductase activity
HBA75_RS28575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBA75_RS28610	COG1609	Transcriptional regulator
HBA75_RS28625	COG0561	phosphatase activity
HBA75_RS28650	COG1475	DNA binding
HBA75_RS28670	COG1132	(ABC) transporter
HBA75_RS28675	COG1131	(ABC) transporter
HBA75_RS28705	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS28705	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_RS28740	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HBA75_RS28760	COG1131	(ABC) transporter
HBA75_RS28770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBA75_RS28775	COG1132	(ABC) transporter
HBA75_RS28825	COG2801	Transposase and inactivated derivatives
HBA75_RS28840	COG0457	Tetratricopeptide repeat
HBA75_RS28850	COG3397	chitin binding
HBA75_RS28895	COG0697	spore germination
HBA75_RS28905	COG3397	chitin binding
HBA75_RS28910	COG0823	Involved in the tonB-independent uptake of proteins
HBA75_RS28920	COG1183	phosphatidylcholine synthase activity
HBA75_RS28945	COG5002	protein histidine kinase activity
HBA75_RS28945	COG3850	Histidine kinase
HBA75_RS28950	COG0745	RESPONSE REGULATOR receiver
HBA75_RS28960	COG1136	(ABC) transporter
HBA75_RS28985	COG2814	Major facilitator Superfamily
HBA75_RS29010	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_RS29015	COG2259	Doxx family
HBA75_RS29035	COG3104	oligopeptide transport
HBA75_RS29055	COG1073	alpha beta
HBA75_RS29065	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS29110	COG1131	(ABC) transporter
HBA75_RS29145	COG4974	Belongs to the 'phage' integrase family
HBA75_RS29195	COG1309	transcriptional regulator
HBA75_RS29205	COG1136	(ABC) transporter
HBA75_RS29240	COG0457	Tetratricopeptide repeat
HBA75_RS29295	COG1802	Transcriptional regulator
HBA75_RS29300	COG0697	spore germination
HBA75_RS29320	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HBA75_RS29335	COG0456	acetyltransferase
HBA75_RS29345	COG2184	nucleotidyltransferase activity
HBA75_RS29355	COG1522	sequence-specific DNA binding
HBA75_RS29360	COG0531	amino acid
HBA75_RS29380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBA75_RS29400	COG0824	Thioesterase
HBA75_RS29405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_RS29430	COG0546	phosphoglycolate phosphatase activity
HBA75_RS29435	COG1349	DNA-binding transcription factor activity
HBA75_RS29620	COG3344	reverse transcriptase
HBA75_RS29635	COG3344	reverse transcriptase
HBA75_RS29780	COG0457	Tetratricopeptide repeat
HBA75_RS29795	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HBA75_RS29800	COG0494	nUDIX hydrolase
HBA75_RS29805	COG0542	response to heat
HBA75_RS29840	COG1522	sequence-specific DNA binding
HBA75_RS29845	COG0288	reversible hydration of carbon dioxide
HBA75_RS29850	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
HBA75_RS29855	COG2233	PERMEase
HBA75_RS29880	COG1687	branched-chain amino acid
HBA75_RS29885	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HBA75_RS29890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_RS29895	COG1361	Conserved repeat domain
HBA75_RS29925	COG0741	lytic transglycosylase activity
HBA75_RS29930	COG0739	heme binding
HBA75_RS29935	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS29935	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_RS29935	COG1388	LysM domain
HBA75_RS29950	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS30030	COG3853	Toxic anion resistance protein (TelA)
HBA75_RS30040	COG0861	Integral membrane protein TerC family
HBA75_RS30045	COG2310	stress, protein
HBA75_RS30050	COG2310	stress, protein
HBA75_RS30055	COG2310	stress, protein
HBA75_RS30060	COG1940	carbohydrate kinase activity
HBA75_RS30085	COG2270	Major facilitator Superfamily
HBA75_RS30135	COG1116	anion transmembrane transporter activity
HBA75_RS30140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBA75_RS30145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBA75_RS30165	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HBA75_RS30195	COG1263	PTS System
HBA75_RS30195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBA75_RS30195	COG2190	(PTS) system
HBA75_RS30200	COG0366	Alpha amylase catalytic
HBA75_RS30205	COG0277	FAD linked oxidase domain protein
HBA75_RS30220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBA75_RS30225	COG0549	Belongs to the carbamate kinase family
HBA75_RS30255	COG0840	transmembrane signaling receptor activity
HBA75_RS30265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBA75_RS30270	COG0765	amino acid transport
HBA75_RS30295	COG2814	Major facilitator Superfamily
HBA75_RS30300	COG3541	Predicted nucleotidyltransferase
HBA75_RS30320	COG5002	protein histidine kinase activity
HBA75_RS30345	COG0166	Belongs to the GPI family
HBA75_RS30355	COG0492	ferredoxin-NADP+ reductase activity
HBA75_RS30360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_RS30365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_RS30370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_RS30390	COG0450	alkyl hydroperoxide reductase
HBA75_RS30405	COG1473	amidohydrolase
HBA75_RS30435	COG4807	Protein conserved in bacteria
HBA75_RS30440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBA75_RS30445	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_RS30445	COG1388	LysM domain
HBA75_RS30445	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_RS30455	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_RS30565	COG0582	viral genome integration into host DNA
HBA75_RS30615	COG3829	transcription factor binding
HBA75_RS30630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HBA75_RS30635	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HBA75_RS30655	COG0535	radical SAM domain protein
HBA75_RS30665	COG0387	Pfam Sodium calcium exchanger
HBA75_RS30670	COG3871	stress protein (general stress protein 26)
HBA75_RS30680	COG2801	Transposase and inactivated derivatives
HBA75_RS30700	COG0586	Pfam SNARE associated Golgi protein
HBA75_RS30710	COG0681	Belongs to the peptidase S26 family
HBA75_RS30720	COG0697	spore germination
HBA75_RS30725	COG2217	Heavy metal translocating P-type atpase
HBA75_RS30730	COG1295	ribonuclease BN
HBA75_RS30740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBA75_RS30755	COG2801	Transposase and inactivated derivatives
HBA75_RS31010	COG2801	Transposase and inactivated derivatives
HBA75_RS31025	COG3611	Membrane attachment protein