locus-tag	class	description
MTX16_RS00005	COG1802	Transcriptional regulator
MTX16_RS00005	COG4626	Terminase
MTX16_RS00015	COG0740	serine-type endopeptidase activity
MTX16_RS00075	COG4824	toxin secretion phage lysis holin
MTX16_RS00125	COG2124	cytochrome p450
MTX16_RS00160	COG0561	phosphatase activity
MTX16_RS00165	COG5002	protein histidine kinase activity
MTX16_RS00170	COG0768	penicillin binding
MTX16_RS00180	COG1819	glycosyl
MTX16_RS00185	COG1794	racemase activity, acting on amino acids and derivatives
MTX16_RS00210	COG2205	protein histidine kinase activity
MTX16_RS00275	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MTX16_RS00280	COG0604	alcohol dehydrogenase
MTX16_RS00285	COG0671	phosphoesterase, PA-phosphatase related
MTX16_RS00290	COG0768	penicillin binding
MTX16_RS00340	COG0693	protein deglycase activity
MTX16_RS00350	COG2814	Major facilitator Superfamily
MTX16_RS00365	COG0584	glycerophosphoryl diester phosphodiesterase
MTX16_RS00385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTX16_RS00390	COG0697	spore germination
MTX16_RS00425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MTX16_RS00435	COG2223	nitrite transmembrane transporter activity
MTX16_RS00455	COG0592	DNA-directed DNA polymerase activity
MTX16_RS00500	COG4667	esterase of the alpha-beta hydrolase superfamily
MTX16_RS00540	COG0322	excinuclease ABC activity
MTX16_RS00575	COG1819	glycosyl
MTX16_RS00590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTX16_RS00625	COG0745	RESPONSE REGULATOR receiver
MTX16_RS00630	COG5002	protein histidine kinase activity
MTX16_RS00645	COG1136	(ABC) transporter
MTX16_RS00650	COG0577	efflux transmembrane transporter activity
MTX16_RS00655	COG1073	alpha beta
MTX16_RS00660	COG0657	acetylesterase activity
MTX16_RS00665	COG0076	glutamate decarboxylase activity
MTX16_RS00680	COG1523	belongs to the glycosyl hydrolase 13 family
MTX16_RS00685	COG3227	Zinc metalloprotease (Elastase)
MTX16_RS00690	COG0737	Belongs to the 5'-nucleotidase family
MTX16_RS00710	COG0201	protein transport
MTX16_RS00715	COG0697	spore germination
MTX16_RS00720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTX16_RS00725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MTX16_RS00755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS00770	COG2959	enzyme of heme biosynthesis
MTX16_RS00810	COG1309	transcriptional regulator
MTX16_RS00840	COG3284	Transcriptional regulator
MTX16_RS00860	COG1349	DNA-binding transcription factor activity
MTX16_RS00875	COG1959	2 iron, 2 sulfur cluster binding
MTX16_RS00890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MTX16_RS00895	COG0508	dehydrogenase complex catalyzes the overall conversion of
MTX16_RS00900	COG0022	dehydrogenase e1 component
MTX16_RS00905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MTX16_RS00920	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS00950	COG4176	ABC-type proline glycine betaine transport system permease component
MTX16_RS00955	COG0517	IMP dehydrogenase activity
MTX16_RS00955	COG4175	Glycine betaine
MTX16_RS00985	COG2153	protein acetylation
MTX16_RS00990	COG3397	chitin binding
MTX16_RS01030	COG2205	protein histidine kinase activity
MTX16_RS01035	COG2226	methyltransferase
MTX16_RS01040	COG2315	Protein conserved in bacteria
MTX16_RS01085	COG0456	acetyltransferase
MTX16_RS01090	COG3973	AAA domain
MTX16_RS01105	COG0514	ATP-dependent DNA helicase (RecQ)
MTX16_RS01145	COG4637	Psort location Cytoplasmic, score
MTX16_RS01160	COG3397	chitin binding
MTX16_RS01175	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MTX16_RS01180	COG1115	amino acid carrier protein
MTX16_RS01185	COG1012	belongs to the aldehyde dehydrogenase family
MTX16_RS01190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MTX16_RS01200	COG3938	Belongs to the proline racemase family
MTX16_RS01205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTX16_RS01245	COG0586	Pfam SNARE associated Golgi protein
MTX16_RS01255	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MTX16_RS01265	COG4166	transmembrane transport
MTX16_RS01275	COG4948	Mandelate Racemase Muconate Lactonizing
MTX16_RS01290	COG0667	Aldo Keto reductase
MTX16_RS01335	COG5002	protein histidine kinase activity
MTX16_RS01335	COG3850	Histidine kinase
MTX16_RS01340	COG0745	RESPONSE REGULATOR receiver
MTX16_RS01380	COG1164	Oligoendopeptidase f
MTX16_RS01385	COG1307	EDD domain protein, DegV family
MTX16_RS01425	COG2814	Major facilitator Superfamily
MTX16_RS01435	COG1664	Polymer-forming cytoskeletal
MTX16_RS01440	COG0789	Transcriptional regulator
MTX16_RS01445	COG4533	DNA binding
MTX16_RS01450	COG0477	Major facilitator Superfamily
MTX16_RS01450	COG2814	Major facilitator Superfamily
MTX16_RS01470	COG2261	transglycosylase associated protein
MTX16_RS01485	COG2226	methyltransferase
MTX16_RS01520	COG0436	Aminotransferase
MTX16_RS01525	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MTX16_RS01550	COG1131	(ABC) transporter
MTX16_RS01600	COG0628	permease
MTX16_RS01615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTX16_RS01620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTX16_RS01625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MTX16_RS01665	COG2746	aminoglycoside 3-N-acetyltransferase activity
MTX16_RS01675	COG0697	spore germination
MTX16_RS01685	COG2318	DinB family
MTX16_RS01705	COG4912	Dna alkylation repair
MTX16_RS01710	COG0346	lactoylglutathione lyase activity
MTX16_RS01725	COG0861	Integral membrane protein TerC family
MTX16_RS01730	COG1368	sulfuric ester hydrolase activity
MTX16_RS01735	COG0488	(ABC) transporter
MTX16_RS01740	COG1033	growth of symbiont in host cell
MTX16_RS01740	COG2409	Drug exporters of the RND superfamily
MTX16_RS01745	COG1309	transcriptional regulator
MTX16_RS01760	COG0287	Prephenate dehydrogenase
MTX16_RS01775	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MTX16_RS01775	COG1605	Chorismate mutase
MTX16_RS01820	COG3584	3D domain protein
MTX16_RS01820	COG1388	LysM domain
MTX16_RS01835	COG0346	lactoylglutathione lyase activity
MTX16_RS01850	COG1309	transcriptional regulator
MTX16_RS01860	COG1595	DNA-templated transcription, initiation
MTX16_RS01885	COG1879	ABC-type sugar transport system periplasmic component
MTX16_RS01890	COG1172	Belongs to the binding-protein-dependent transport system permease family
MTX16_RS01895	COG1172	Belongs to the binding-protein-dependent transport system permease family
MTX16_RS01905	COG2390	Transcriptional regulator
MTX16_RS01910	COG1070	Carbohydrate kinase
MTX16_RS01925	COG2329	Antibiotic biosynthesis monooxygenase
MTX16_RS01945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MTX16_RS01960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MTX16_RS01965	COG4187	Peptidase family M20/M25/M40
MTX16_RS01970	COG1414	Transcriptional regulator
MTX16_RS01975	COG0833	amino acid
MTX16_RS01985	COG3239	Fatty acid desaturase
MTX16_RS01995	COG2720	vancomycin resistance protein
MTX16_RS02000	COG1785	Belongs to the alkaline phosphatase family
MTX16_RS02010	COG3655	Transcriptional regulator
MTX16_RS02030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS02035	COG0346	lactoylglutathione lyase activity
MTX16_RS02060	COG0714	Associated with various cellular activities
MTX16_RS02085	COG0463	Glycosyl transferase, family 2
MTX16_RS02115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MTX16_RS02120	COG0753	catalase activity
MTX16_RS02160	COG0714	Associated with various cellular activities
MTX16_RS02200	COG0778	Nitroreductase
MTX16_RS02205	COG1846	Transcriptional regulator
MTX16_RS02240	COG0577	efflux transmembrane transporter activity
MTX16_RS02240	COG1136	(ABC) transporter
MTX16_RS02295	COG0456	acetyltransferase
MTX16_RS02315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTX16_RS02360	COG0730	response to heat
MTX16_RS02370	COG0833	amino acid
MTX16_RS02380	COG4335	DNA alkylation repair
MTX16_RS02415	COG0768	penicillin binding
MTX16_RS02450	COG1984	allophanate hydrolase subunit 2
MTX16_RS02455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MTX16_RS02460	COG1414	Transcriptional regulator
MTX16_RS02470	COG3142	Participates in the control of copper homeostasis
MTX16_RS02480	COG1061	Type III restriction enzyme res subunit
MTX16_RS02490	COG1960	acyl-CoA dehydrogenase activity
MTX16_RS02525	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MTX16_RS02545	COG3848	Pyruvate phosphate dikinase
MTX16_RS02545	COG0574	Belongs to the PEP-utilizing enzyme family
MTX16_RS02555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTX16_RS02570	COG5577	PFAM Coat F domain
MTX16_RS02575	COG3403	YqcI/YcgG family
MTX16_RS02580	COG1280	lysine exporter protein (LysE YggA)
MTX16_RS02585	COG1113	amino acid transport
MTX16_RS02615	COG1063	alcohol dehydrogenase
MTX16_RS02625	COG1027	Aspartate ammonia-lyase
MTX16_RS02630	COG0252	asparaginase activity
MTX16_RS02635	COG1396	sequence-specific DNA binding
MTX16_RS02660	COG5002	protein histidine kinase activity
MTX16_RS02685	COG2207	Transcriptional regulator
MTX16_RS02700	COG0322	excinuclease ABC activity
MTX16_RS02705	COG0531	amino acid
MTX16_RS02710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MTX16_RS02720	COG0281	malic enzyme
MTX16_RS02735	COG0531	amino acid
MTX16_RS02740	COG0697	spore germination
MTX16_RS02745	COG0784	Response regulator, receiver
MTX16_RS02750	COG4191	Histidine kinase
MTX16_RS02755	COG2066	Belongs to the glutaminase family
MTX16_RS02760	COG1115	amino acid carrier protein
MTX16_RS02795	COG0737	Belongs to the 5'-nucleotidase family
MTX16_RS02800	COG2267	carboxylic ester hydrolase activity
MTX16_RS02805	COG1335	isochorismatase
MTX16_RS02825	COG0583	DNA-binding transcription factor activity
MTX16_RS02830	COG1846	Transcriptional regulator
MTX16_RS02835	COG0598	Magnesium transport protein CorA
MTX16_RS02855	COG1073	alpha beta
MTX16_RS02875	COG0415	Belongs to the DNA photolyase family
MTX16_RS02880	COG0288	reversible hydration of carbon dioxide
MTX16_RS02890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MTX16_RS02895	COG5609	conserved protein (DUF2294)
MTX16_RS02910	COG0697	spore germination
MTX16_RS02920	COG0456	acetyltransferase
MTX16_RS02925	COG1575	Belongs to the MenA family. Type 1 subfamily
MTX16_RS02950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS02960	COG0798	PFAM Bile acid sodium symporter
MTX16_RS02965	COG0346	lactoylglutathione lyase activity
MTX16_RS02970	COG0640	Transcriptional regulator
MTX16_RS02980	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MTX16_RS02985	COG3320	Male sterility
MTX16_RS02985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MTX16_RS02990	COG1309	transcriptional regulator
MTX16_RS02995	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS03000	COG1522	sequence-specific DNA binding
MTX16_RS03015	COG0346	lactoylglutathione lyase activity
MTX16_RS03060	COG0814	amino acid
MTX16_RS03075	COG3409	Peptidoglycan-binding domain 1 protein
MTX16_RS03075	COG5632	N-Acetylmuramoyl-L-alanine amidase
MTX16_RS03080	COG0583	DNA-binding transcription factor activity
MTX16_RS03105	COG1131	(ABC) transporter
MTX16_RS03110	COG1725	Transcriptional regulator
MTX16_RS03145	COG0745	RESPONSE REGULATOR receiver
MTX16_RS03150	COG5002	protein histidine kinase activity
MTX16_RS03150	COG3850	Histidine kinase
MTX16_RS03175	COG2814	Major facilitator Superfamily
MTX16_RS03195	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MTX16_RS03210	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MTX16_RS03225	COG0577	efflux transmembrane transporter activity
MTX16_RS03245	COG5002	protein histidine kinase activity
MTX16_RS03245	COG3850	Histidine kinase
MTX16_RS03255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTX16_RS03265	COG1619	proteins homologs of microcin C7 resistance protein MccF
MTX16_RS03280	COG0561	phosphatase activity
MTX16_RS03290	COG1609	Transcriptional regulator
MTX16_RS03295	COG0457	Tetratricopeptide repeat
MTX16_RS03325	COG0534	Mate efflux family protein
MTX16_RS03345	COG2814	Major facilitator Superfamily
MTX16_RS03350	COG1309	transcriptional regulator
MTX16_RS03365	COG1522	sequence-specific DNA binding
MTX16_RS03370	COG0531	amino acid
MTX16_RS03385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MTX16_RS03405	COG0662	Cupin 2, conserved barrel domain protein
MTX16_RS03410	COG2207	Transcriptional regulator
MTX16_RS03410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTX16_RS03430	COG5632	N-Acetylmuramoyl-L-alanine amidase
MTX16_RS03430	COG3409	Peptidoglycan-binding domain 1 protein
MTX16_RS03555	COG1876	peptidase activity
MTX16_RS03560	COG2843	Capsule synthesis protein
MTX16_RS03570	COG0477	Major facilitator Superfamily
MTX16_RS03585	COG1846	Transcriptional regulator
MTX16_RS03590	COG2814	Major facilitator Superfamily
MTX16_RS03600	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MTX16_RS03605	COG1131	(ABC) transporter
MTX16_RS03625	COG2031	fatty acid transporter
MTX16_RS03635	COG2249	NAD(P)H dehydrogenase (quinone) activity
MTX16_RS03690	COG1288	antiporter activity
MTX16_RS03695	COG2356	endonuclease I
MTX16_RS03700	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MTX16_RS03720	COG1733	regulation of RNA biosynthetic process
MTX16_RS03725	COG0778	Nitroreductase
MTX16_RS03755	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS03765	COG1131	(ABC) transporter
MTX16_RS03790	COG1011	Hydrolase
MTX16_RS03800	COG2365	Tyrosine phosphatase family
MTX16_RS03835	COG0628	permease
MTX16_RS03905	COG1253	flavin adenine dinucleotide binding
MTX16_RS03910	COG0789	Transcriptional regulator
MTX16_RS03920	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MTX16_RS03945	COG0697	spore germination
MTX16_RS03955	COG1357	PFAM Pentapeptide repeats (8 copies)
MTX16_RS03960	COG3813	Protein conserved in bacteria
MTX16_RS03965	COG2706	6-phosphogluconolactonase activity
MTX16_RS03970	COG1070	Carbohydrate kinase
MTX16_RS03980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MTX16_RS03985	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MTX16_RS03990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MTX16_RS03995	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MTX16_RS04005	COG0604	alcohol dehydrogenase
MTX16_RS04010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTX16_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS04040	COG0840	transmembrane signaling receptor activity
MTX16_RS04050	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MTX16_RS04050	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MTX16_RS04055	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MTX16_RS04055	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MTX16_RS04060	COG1733	regulation of RNA biosynthetic process
MTX16_RS04080	COG0656	L-ascorbic acid biosynthetic process
MTX16_RS04085	COG2814	Major facilitator Superfamily
MTX16_RS04115	COG0814	amino acid
MTX16_RS04150	COG1733	regulation of RNA biosynthetic process
MTX16_RS04155	COG2188	Transcriptional regulator
MTX16_RS04160	COG0673	inositol 2-dehydrogenase activity
MTX16_RS04165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MTX16_RS04170	COG1733	regulation of RNA biosynthetic process
MTX16_RS04175	COG1733	regulation of RNA biosynthetic process
MTX16_RS04200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTX16_RS04220	COG0384	phenazine biosynthesis protein PhzF
MTX16_RS04245	COG0318	PFAM AMP-dependent synthetase and ligase
MTX16_RS04250	COG2249	NAD(P)H dehydrogenase (quinone) activity
MTX16_RS04255	COG1733	regulation of RNA biosynthetic process
MTX16_RS04260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MTX16_RS04290	COG1191	sigma factor activity
MTX16_RS04350	COG1151	hydroxylamine reductase activity
MTX16_RS04385	COG2072	flavoprotein involved in K transport
MTX16_RS04420	COG1113	amino acid transport
MTX16_RS04425	COG2814	Major facilitator Superfamily
MTX16_RS04455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MTX16_RS04460	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MTX16_RS04470	COG1247	-acetyltransferase
MTX16_RS04475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTX16_RS04480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTX16_RS04485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTX16_RS04490	COG3739	integral membrane protein
MTX16_RS04510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS04525	COG0583	DNA-binding transcription factor activity
MTX16_RS04545	COG1193	negative regulation of DNA recombination
MTX16_RS04560	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MTX16_RS04565	COG1164	Oligoendopeptidase f
MTX16_RS04590	COG3781	membrane
MTX16_RS04605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MTX16_RS04630	COG0584	glycerophosphoryl diester phosphodiesterase
MTX16_RS04640	COG0640	Transcriptional regulator
MTX16_RS04645	COG0604	alcohol dehydrogenase
MTX16_RS04655	COG0457	Tetratricopeptide repeat
MTX16_RS04665	COG2808	Putative FMN-binding domain
MTX16_RS04670	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MTX16_RS04685	COG0277	FAD linked oxidase domain protein
MTX16_RS04715	COG3852	Histidine kinase
MTX16_RS04725	COG1285	pathogenesis
MTX16_RS04735	COG2514	catechol 2,3-dioxygenase activity
MTX16_RS04740	COG2720	vancomycin resistance protein
MTX16_RS04775	COG0716	FMN binding
MTX16_RS04785	COG0494	nUDIX hydrolase
MTX16_RS04805	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS04815	COG0165	Argininosuccinate lyase
MTX16_RS04830	COG4145	pantothenate transmembrane transporter activity
MTX16_RS04840	COG1012	belongs to the aldehyde dehydrogenase family
MTX16_RS04845	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS04855	COG1657	PFAM Prenyltransferase squalene oxidase
MTX16_RS04860	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
MTX16_RS04865	COG2962	Rard protein
MTX16_RS04870	COG3326	Membrane
MTX16_RS04885	COG0489	protein tyrosine kinase activity
MTX16_RS04895	COG0314	molybdopterin synthase activity
MTX16_RS04900	COG0303	'Molybdopterin
MTX16_RS04905	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MTX16_RS04910	COG2116	formate transmembrane transporter activity
MTX16_RS04920	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MTX16_RS04925	COG5609	conserved protein (DUF2294)
MTX16_RS04930	COG2427	Protein of unknown function (DUF1641)
MTX16_RS04935	COG3383	formate dehydrogenase (NAD+) activity
MTX16_RS04940	COG0697	spore germination
MTX16_RS04955	COG0531	amino acid
MTX16_RS04990	COG2226	methyltransferase
MTX16_RS04995	COG4166	transmembrane transport
MTX16_RS05000	COG4166	transmembrane transport
MTX16_RS05005	COG4166	transmembrane transport
MTX16_RS05015	COG1316	TRANSCRIPTIONal
MTX16_RS05025	COG1595	DNA-templated transcription, initiation
MTX16_RS05035	COG1131	(ABC) transporter
MTX16_RS05055	COG0673	inositol 2-dehydrogenase activity
MTX16_RS05060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MTX16_RS05065	COG0187	DNA topoisomerase II activity
MTX16_RS05070	COG1832	CoA-binding protein
MTX16_RS05075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MTX16_RS05080	COG0745	RESPONSE REGULATOR receiver
MTX16_RS05100	COG4841	protein insertion into membrane
MTX16_RS05105	COG0824	Thioesterase
MTX16_RS05140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MTX16_RS05150	COG1122	ATPase activity
MTX16_RS05155	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MTX16_RS05185	COG2211	Major facilitator Superfamily
MTX16_RS05195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MTX16_RS05210	COG0183	Belongs to the thiolase family
MTX16_RS05215	COG0318	PFAM AMP-dependent synthetase and ligase
MTX16_RS05220	COG1268	BioY protein
MTX16_RS05225	COG0318	PFAM AMP-dependent synthetase and ligase
MTX16_RS05275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTX16_RS05285	COG5002	protein histidine kinase activity
MTX16_RS05290	COG0400	carboxylic ester hydrolase activity
MTX16_RS05295	COG0346	lactoylglutathione lyase activity
MTX16_RS05300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MTX16_RS05305	COG0069	glutamate synthase activity
MTX16_RS05310	COG1902	pentaerythritol trinitrate reductase activity
MTX16_RS05315	COG1329	Transcriptional regulator
MTX16_RS05320	COG0010	Belongs to the arginase family
MTX16_RS05370	COG4846	Membrane protein involved in cytochrome C biogenesis
MTX16_RS05375	COG0785	Cytochrome C biogenesis protein
MTX16_RS05385	COG1473	amidohydrolase
MTX16_RS05395	COG1131	(ABC) transporter
MTX16_RS05410	COG0583	DNA-binding transcription factor activity
MTX16_RS05420	COG1346	cytolysis
MTX16_RS05435	COG0730	response to heat
MTX16_RS05460	COG1132	(ABC) transporter
MTX16_RS05465	COG1132	(ABC) transporter
MTX16_RS05490	COG3639	organic phosphonate transmembrane transporter activity
MTX16_RS05500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTX16_RS05505	COG0737	Belongs to the 5'-nucleotidase family
MTX16_RS05515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MTX16_RS05535	COG1695	Transcriptional regulator
MTX16_RS05545	COG3409	Peptidoglycan-binding domain 1 protein
MTX16_RS05545	COG5632	N-Acetylmuramoyl-L-alanine amidase
MTX16_RS05545	COG1388	LysM domain
MTX16_RS05550	COG0739	heme binding
MTX16_RS05555	COG0741	lytic transglycosylase activity
MTX16_RS05585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MTX16_RS05590	COG0174	glutamine synthetase
MTX16_RS05595	COG0789	Transcriptional regulator
MTX16_RS05600	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MTX16_RS05605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MTX16_RS05610	COG2860	membrane
MTX16_RS05620	COG0464	growth
MTX16_RS05655	COG1388	LysM domain
MTX16_RS05655	COG3584	3D domain protein
MTX16_RS05660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MTX16_RS05660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MTX16_RS05660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MTX16_RS05665	COG1105	Belongs to the carbohydrate kinase PfkB family
MTX16_RS05670	COG1349	DNA-binding transcription factor activity
MTX16_RS05675	COG1979	alcohol dehydrogenase
MTX16_RS05680	COG2322	membrane
MTX16_RS05690	COG1113	amino acid transport
MTX16_RS05700	COG1408	metallophosphoesterase
MTX16_RS05705	COG2116	formate transmembrane transporter activity
MTX16_RS05720	COG2217	Heavy metal translocating P-type atpase
MTX16_RS05725	COG2608	mercury ion transmembrane transporter activity
MTX16_RS05730	COG1937	Protein conserved in bacteria
MTX16_RS05740	COG2819	hydrolase of the alpha beta superfamily
MTX16_RS05745	COG1120	ATPase activity
MTX16_RS05750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTX16_RS05755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTX16_RS05760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTX16_RS05765	COG0708	Exodeoxyribonuclease III
MTX16_RS05770	COG2169	Transcriptional regulator
MTX16_RS05775	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MTX16_RS05780	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MTX16_RS05800	COG2267	carboxylic ester hydrolase activity
MTX16_RS05805	COG3300	MHYT domain
MTX16_RS05805	COG5001	Diguanylate cyclase
MTX16_RS05825	COG1086	Polysaccharide biosynthesis protein
MTX16_RS05845	COG1346	cytolysis
MTX16_RS05855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTX16_RS05870	COG0823	Involved in the tonB-independent uptake of proteins
MTX16_RS05880	COG3773	Cell wall hydrolase
MTX16_RS05890	COG1368	sulfuric ester hydrolase activity
MTX16_RS05895	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MTX16_RS05920	COG4550	Control of competence regulator ComK, YlbF/YmcA
MTX16_RS05930	COG1013	pyruvate-flavodoxin oxidoreductase activity
MTX16_RS05935	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MTX16_RS05935	COG0674	pyruvate-flavodoxin oxidoreductase activity
MTX16_RS05945	COG2359	stage V sporulation protein S
MTX16_RS05950	COG1692	metallophosphoesterase
MTX16_RS05970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MTX16_RS05975	COG1426	Protein conserved in bacteria
MTX16_RS05990	COG0300	oxidoreductase activity
MTX16_RS05995	COG0612	Peptidase, M16
MTX16_RS06000	COG0612	Peptidase, M16
MTX16_RS06005	COG1079	Belongs to the binding-protein-dependent transport system permease family
MTX16_RS06010	COG4603	Belongs to the binding-protein-dependent transport system permease family
MTX16_RS06015	COG3845	ABC transporter
MTX16_RS06020	COG1744	ABC transporter substrate-binding protein PnrA-like
MTX16_RS06025	COG2188	Transcriptional regulator
MTX16_RS06040	COG0740	serine-type endopeptidase activity
MTX16_RS06045	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MTX16_RS06055	COG0527	aspartate kinase activity
MTX16_RS06060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MTX16_RS06065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MTX16_RS06070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MTX16_RS06075	COG1873	PFAM PRC-barrel domain
MTX16_RS06080	COG0612	Peptidase, M16
MTX16_RS06085	COG0726	polysaccharide deacetylase
MTX16_RS06100	COG0196	riboflavin kinase activity
MTX16_RS06110	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MTX16_RS06115	COG1550	Protein conserved in bacteria
MTX16_RS06125	COG1358	cellular component organization or biogenesis
MTX16_RS06130	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MTX16_RS06135	COG0195	Participates in both transcription termination and antitermination
MTX16_RS06155	COG0750	zinc metalloprotease
MTX16_RS06165	COG4589	Belongs to the CDS family
MTX16_RS06210	COG4974	Belongs to the 'phage' integrase family
MTX16_RS06220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MTX16_RS06225	COG0758	DNA mediated transformation
MTX16_RS06230	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MTX16_RS06270	COG1837	Belongs to the UPF0109 family
MTX16_RS06280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MTX16_RS06290	COG0552	protein localization to endoplasmic reticulum
MTX16_RS06295	COG1196	nuclear chromosome segregation
MTX16_RS06305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MTX16_RS06310	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS06315	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MTX16_RS06330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MTX16_RS06335	COG1461	Dihydroxyacetone kinase
MTX16_RS06340	COG1302	Protein conserved in bacteria
MTX16_RS06355	COG1564	THIamine pyrophosphokinase
MTX16_RS06360	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MTX16_RS06370	COG0515	serine threonine protein kinase
MTX16_RS06370	COG2815	serine threonine protein kinase
MTX16_RS06375	COG0631	protein serine/threonine phosphatase activity
MTX16_RS06385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MTX16_RS06385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MTX16_RS06400	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MTX16_RS06405	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MTX16_RS06425	COG1561	YicC-like family, N-terminal region
MTX16_RS06430	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MTX16_RS06445	COG0006	proline dipeptidase activity
MTX16_RS06465	COG3069	C4-dicarboxylate transmembrane transporter activity
MTX16_RS06530	COG0564	pseudouridine synthase activity
MTX16_RS06550	COG3599	regulation of cell shape
MTX16_RS06555	COG2302	S4 RNA-binding domain
MTX16_RS06560	COG0762	integral membrane protein
MTX16_RS06570	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MTX16_RS06580	COG1873	PFAM PRC-barrel domain
MTX16_RS06585	COG1191	sigma factor activity
MTX16_RS06590	COG1191	sigma factor activity
MTX16_RS06600	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MTX16_RS06605	COG0849	cell division
MTX16_RS06625	COG0772	Belongs to the SEDS family
MTX16_RS06645	COG0768	penicillin binding
MTX16_RS06650	COG0768	penicillin binding
MTX16_RS06670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MTX16_RS06685	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MTX16_RS06690	COG1399	metal-binding, possibly nucleic acid-binding protein
MTX16_RS06700	COG3480	Lon protease (S16) C-terminal proteolytic domain
MTX16_RS06705	COG1752	Esterase of the alpha-beta hydrolase superfamily
MTX16_RS06710	COG3314	Sporulation integral membrane protein YlbJ
MTX16_RS06720	COG0742	ribosomal rna small subunit methyltransferase
MTX16_RS06735	COG3679	Belongs to the UPF0342 family
MTX16_RS06740	COG0406	alpha-ribazole phosphatase activity
MTX16_RS06755	COG2340	Cysteine-rich secretory protein family
MTX16_RS06770	COG3336	cytochrome c oxidase
MTX16_RS06805	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MTX16_RS06810	COG0772	Belongs to the SEDS family
MTX16_RS06820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MTX16_RS06825	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MTX16_RS06835	COG4896	Protein conserved in bacteria
MTX16_RS06850	COG1217	gtp-binding protein TYPA
MTX16_RS06860	COG0483	inositol monophosphate 1-phosphatase activity
MTX16_RS06880	COG1982	Orn Lys Arg decarboxylase major
MTX16_RS06930	COG0022	dehydrogenase e1 component
MTX16_RS06935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MTX16_RS06950	COG0561	phosphatase activity
MTX16_RS06960	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MTX16_RS06965	COG0569	domain protein
MTX16_RS06985	COG0583	DNA-binding transcription factor activity
MTX16_RS06990	COG0517	IMP dehydrogenase activity
MTX16_RS07000	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
MTX16_RS07010	COG4703	Protein of unknown function (DUF1797)
MTX16_RS07025	COG2200	EAL domain
MTX16_RS07030	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS07035	COG1408	metallophosphoesterase
MTX16_RS07080	COG2814	Major facilitator Superfamily
MTX16_RS07100	COG3209	COG3209 Rhs family protein
MTX16_RS07110	COG2205	protein histidine kinase activity
MTX16_RS07120	COG0436	Aminotransferase
MTX16_RS07125	COG1609	Transcriptional regulator
MTX16_RS07130	COG3833	ABC-type maltose transport systems, permease component
MTX16_RS07135	COG1175	transmembrane transport
MTX16_RS07140	COG2182	Extracellular solute-binding protein
MTX16_RS07150	COG0366	Alpha amylase catalytic
MTX16_RS07155	COG3842	ATPase activity
MTX16_RS07195	COG0183	Belongs to the thiolase family
MTX16_RS07230	COG1695	Transcriptional regulator
MTX16_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS07255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MTX16_RS07260	COG0436	Aminotransferase
MTX16_RS07295	COG2084	Dehydrogenase
MTX16_RS07305	COG2199	diguanylate cyclase activity
MTX16_RS07310	COG0778	Nitroreductase
MTX16_RS07335	COG1263	PTS System
MTX16_RS07335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTX16_RS07335	COG2190	(PTS) system
MTX16_RS07340	COG3711	transcriptional antiterminator
MTX16_RS07350	COG2188	Transcriptional regulator
MTX16_RS07365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MTX16_RS07390	COG1547	Domain of unknown function (DUF309)
MTX16_RS07395	COG0456	acetyltransferase
MTX16_RS07400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MTX16_RS07405	COG4086	secreted protein
MTX16_RS07410	COG0561	phosphatase activity
MTX16_RS07415	COG0697	spore germination
MTX16_RS07430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MTX16_RS07455	COG0733	neurotransmitter:sodium symporter activity
MTX16_RS07475	COG1686	Belongs to the peptidase S11 family
MTX16_RS07480	COG1725	Transcriptional regulator
MTX16_RS07485	COG1131	(ABC) transporter
MTX16_RS07505	COG1846	Transcriptional regulator
MTX16_RS07520	COG0598	Magnesium transport protein CorA
MTX16_RS07545	COG4974	Belongs to the 'phage' integrase family
MTX16_RS07555	COG0735	belongs to the Fur family
MTX16_RS07560	COG1300	Membrane
MTX16_RS07580	COG0667	Aldo Keto reductase
MTX16_RS07585	COG0656	L-ascorbic acid biosynthetic process
MTX16_RS07590	COG0456	acetyltransferase
MTX16_RS07590	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MTX16_RS07600	COG1525	nuclease
MTX16_RS07600	COG4085	toxin activity
MTX16_RS07600	COG0737	Belongs to the 5'-nucleotidase family
MTX16_RS07610	COG0596	Alpha beta hydrolase
MTX16_RS07615	COG2056	Na+-H+ antiporter family
MTX16_RS07620	COG1609	Transcriptional regulator
MTX16_RS07625	COG0456	acetyltransferase
MTX16_RS07630	COG1073	alpha beta
MTX16_RS07645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MTX16_RS07645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MTX16_RS07650	COG0307	riboflavin synthase, alpha
MTX16_RS07680	COG1073	alpha beta
MTX16_RS07680	COG2226	methyltransferase
MTX16_RS07695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MTX16_RS07705	COG1757	Na H antiporter
MTX16_RS07710	COG0737	Belongs to the 5'-nucleotidase family
MTX16_RS07720	COG1522	sequence-specific DNA binding
MTX16_RS07765	COG0300	oxidoreductase activity
MTX16_RS07770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTX16_RS07775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MTX16_RS07780	COG1760	l-serine dehydratase
MTX16_RS07785	COG1760	l-serine dehydratase
MTX16_RS07825	COG2195	Cleaves the N-terminal amino acid of tripeptides
MTX16_RS07830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS07845	COG1376	ErfK ybiS ycfS ynhG family protein
MTX16_RS07850	COG4129	membrane
MTX16_RS07855	COG1126	abc transporter atp-binding protein
MTX16_RS07860	COG0765	amino acid transport
MTX16_RS07865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTX16_RS07890	COG0772	Belongs to the SEDS family
MTX16_RS07895	COG0508	dehydrogenase complex catalyzes the overall conversion of
MTX16_RS07900	COG0022	dehydrogenase e1 component
MTX16_RS07905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MTX16_RS07910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MTX16_RS07925	COG0280	phosphate acetyltransferase
MTX16_RS07930	COG3290	protein histidine kinase activity
MTX16_RS07930	COG3829	transcription factor binding
MTX16_RS07940	COG0584	glycerophosphoryl diester phosphodiesterase
MTX16_RS07945	COG3093	addiction module antidote protein HigA
MTX16_RS07960	COG0750	zinc metalloprotease
MTX16_RS07965	COG0497	DNA recombination
MTX16_RS07975	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MTX16_RS07985	COG0142	geranyltranstransferase activity
MTX16_RS08010	COG1302	Protein conserved in bacteria
MTX16_RS08015	COG0439	Biotin carboxylase
MTX16_RS08020	COG0511	ligase activity, forming carbon-carbon bonds
MTX16_RS08065	COG3854	ATPases associated with a variety of cellular activities
MTX16_RS08090	COG0006	proline dipeptidase activity
MTX16_RS08105	COG3872	metal-dependent enzyme
MTX16_RS08115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MTX16_RS08150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MTX16_RS08160	COG1609	Transcriptional regulator
MTX16_RS08170	COG2076	Multidrug Resistance protein
MTX16_RS08175	COG2076	Multidrug Resistance protein
MTX16_RS08205	COG1131	(ABC) transporter
MTX16_RS08210	COG1725	Transcriptional regulator
MTX16_RS08240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MTX16_RS08305	COG1459	type II secretion system
MTX16_RS08310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MTX16_RS08365	COG0646	methionine synthase
MTX16_RS08365	COG1410	methionine synthase
MTX16_RS08370	COG0646	methionine synthase
MTX16_RS08370	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MTX16_RS08375	COG0626	cystathionine gamma-synthase activity
MTX16_RS08380	COG0626	cystathionine gamma-synthase activity
MTX16_RS08400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTX16_RS08410	COG1940	carbohydrate kinase activity
MTX16_RS08415	COG4483	Protein conserved in bacteria
MTX16_RS08420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MTX16_RS08425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MTX16_RS08430	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MTX16_RS08435	COG0704	Plays a role in the regulation of phosphate uptake
MTX16_RS08445	COG0573	inorganic phosphate transmembrane transporter activity
MTX16_RS08450	COG0573	inorganic phosphate transmembrane transporter activity
MTX16_RS08455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MTX16_RS08460	COG0768	penicillin binding
MTX16_RS08465	COG0477	Major facilitator Superfamily
MTX16_RS08470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MTX16_RS08480	COG5521	maltodextrose utilization protein MalA
MTX16_RS08495	COG0735	belongs to the Fur family
MTX16_RS08500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MTX16_RS08505	COG1121	(ABC) transporter
MTX16_RS08510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTX16_RS08540	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MTX16_RS08545	COG2384	SAM-dependent methyltransferase
MTX16_RS08555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MTX16_RS08560	COG0358	DNA primase activity
MTX16_RS08575	COG0517	IMP dehydrogenase activity
MTX16_RS08590	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MTX16_RS08595	COG0295	cytidine deaminase activity
MTX16_RS08600	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MTX16_RS08610	COG1480	7TM receptor with intracellular HD hydrolase
MTX16_RS08615	COG1702	phosphate starvation-inducible protein PhoH
MTX16_RS08630	COG1610	YqeY-like protein
MTX16_RS08635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MTX16_RS08640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MTX16_RS08645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MTX16_RS08675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MTX16_RS08680	COG1733	regulation of RNA biosynthetic process
MTX16_RS08705	COG1466	dna polymerase III delta subunit
MTX16_RS08715	COG2333	competence protein COMEC
MTX16_RS08715	COG0658	competence protein
MTX16_RS08720	COG2131	deaminase
MTX16_RS08725	COG1555	photosystem II stabilization
MTX16_RS08725	COG1596	polysaccharide export
MTX16_RS08730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MTX16_RS08735	COG2226	methyltransferase
MTX16_RS08740	COG0799	negative regulation of ribosome biogenesis
MTX16_RS08745	COG1713	HD superfamily hydrolase involved in NAD metabolism
MTX16_RS08755	COG1534	Rna-binding protein
MTX16_RS08765	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MTX16_RS08770	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MTX16_RS08805	COG0778	Nitroreductase
MTX16_RS08810	COG2357	RelA SpoT domain protein
MTX16_RS08820	COG1785	Belongs to the alkaline phosphatase family
MTX16_RS08830	COG2267	carboxylic ester hydrolase activity
MTX16_RS08870	COG1404	Belongs to the peptidase S8 family
MTX16_RS08875	COG3186	Phenylalanine-4-hydroxylase
MTX16_RS08885	COG2514	catechol 2,3-dioxygenase activity
MTX16_RS08890	COG2259	Doxx family
MTX16_RS08930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTX16_RS08940	COG1454	alcohol dehydrogenase
MTX16_RS08940	COG1012	belongs to the aldehyde dehydrogenase family
MTX16_RS08945	COG0626	cystathionine gamma-synthase activity
MTX16_RS08950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MTX16_RS08975	COG0768	penicillin binding
MTX16_RS08995	COG0826	peptidase U32
MTX16_RS09000	COG0826	peptidase U32
MTX16_RS09005	COG4122	O-methyltransferase activity
MTX16_RS09010	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MTX16_RS09040	COG0628	permease
MTX16_RS09060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MTX16_RS09075	COG1104	cysteine desulfurase activity
MTX16_RS09080	COG1959	2 iron, 2 sulfur cluster binding
MTX16_RS09085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MTX16_RS09100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MTX16_RS09125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MTX16_RS09135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MTX16_RS09135	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MTX16_RS09140	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MTX16_RS09145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MTX16_RS09145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MTX16_RS09155	COG2244	polysaccharide biosynthetic process
MTX16_RS09160	COG2323	membrane
MTX16_RS09170	COG1862	Preprotein translocase
MTX16_RS09200	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MTX16_RS09230	COG0157	Belongs to the NadC ModD family
MTX16_RS09235	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MTX16_RS09240	COG1104	cysteine desulfurase activity
MTX16_RS09245	COG1827	regulation of RNA biosynthetic process
MTX16_RS09250	COG2258	MOSC domain
MTX16_RS09255	COG0077	Prephenate dehydratase
MTX16_RS09260	COG0577	efflux transmembrane transporter activity
MTX16_RS09265	COG0577	efflux transmembrane transporter activity
MTX16_RS09270	COG1136	(ABC) transporter
MTX16_RS09275	COG5002	protein histidine kinase activity
MTX16_RS09280	COG0745	RESPONSE REGULATOR receiver
MTX16_RS09290	COG3290	protein histidine kinase activity
MTX16_RS09300	COG2868	ribosomal protein
MTX16_RS09310	COG1530	ribonuclease E activity
MTX16_RS09315	COG1994	Peptidase M50
MTX16_RS09320	COG0739	heme binding
MTX16_RS09325	COG2894	cell division
MTX16_RS09345	COG1077	Cell shape determining protein MreB Mrl
MTX16_RS09365	COG0285	dihydrofolate synthase activity
MTX16_RS09380	COG1388	LysM domain
MTX16_RS09390	COG0113	porphobilinogen synthase activity
MTX16_RS09395	COG1587	Uroporphyrinogen-III synthase
MTX16_RS09405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MTX16_RS09415	COG1846	Transcriptional regulator
MTX16_RS09420	COG1764	response to oxidative stress
MTX16_RS09435	COG1067	ATP-dependent peptidase activity
MTX16_RS09435	COG0470	DNA polymerase III
MTX16_RS09480	COG0622	Phosphoesterase
MTX16_RS09495	COG5401	PFAM Sporulation and spore germination
MTX16_RS09515	COG1309	transcriptional regulator
MTX16_RS09525	COG2197	response regulator
MTX16_RS09530	COG2233	PERMEase
MTX16_RS09535	COG0402	S-adenosylhomocysteine deaminase activity
MTX16_RS09540	COG1983	PspC domain protein
MTX16_RS09545	COG1396	sequence-specific DNA binding
MTX16_RS09550	COG0697	spore germination
MTX16_RS09560	COG1959	2 iron, 2 sulfur cluster binding
MTX16_RS09565	COG1668	transmembrane transport
MTX16_RS09570	COG4152	abc transporter atp-binding protein
MTX16_RS09575	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MTX16_RS09580	COG1360	Flagellar Motor Protein
MTX16_RS09585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MTX16_RS09590	COG1876	peptidase activity
MTX16_RS09595	COG0824	Thioesterase
MTX16_RS09600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MTX16_RS09605	COG1053	succinate dehydrogenase
MTX16_RS09610	COG2009	succinate dehydrogenase
MTX16_RS09615	COG1719	4-vinyl reductase, 4VR
MTX16_RS09625	COG3118	belongs to the thioredoxin family
MTX16_RS09630	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MTX16_RS09635	COG2086	electron transfer activity
MTX16_RS09640	COG1024	Enoyl-CoA hydratase
MTX16_RS09645	COG1309	transcriptional regulator
MTX16_RS09650	COG0318	PFAM AMP-dependent synthetase and ligase
MTX16_RS09680	COG2318	DinB family
MTX16_RS09710	COG1131	(ABC) transporter
MTX16_RS09715	COG2205	protein histidine kinase activity
MTX16_RS09720	COG0745	RESPONSE REGULATOR receiver
MTX16_RS09730	COG4895	conserved protein (DUF2196)
MTX16_RS09735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MTX16_RS09745	COG4509	Sortase family
MTX16_RS09750	COG1120	ATPase activity
MTX16_RS09765	COG5386	Cell surface protein
MTX16_RS09775	COG5386	Cell surface protein
MTX16_RS09780	COG1114	Component of the transport system for branched-chain amino acids
MTX16_RS09785	COG1187	pseudouridine synthase activity
MTX16_RS09795	COG1796	DNA polymerase
MTX16_RS09795	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MTX16_RS09800	COG1286	toxin biosynthetic process
MTX16_RS09840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MTX16_RS09850	COG1418	mRNA catabolic process
MTX16_RS09870	COG2814	Major facilitator Superfamily
MTX16_RS09875	COG1566	PFAM secretion protein HlyD family protein
MTX16_RS09880	COG1309	transcriptional regulator
MTX16_RS09885	COG1363	Peptidase, m42
MTX16_RS09910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MTX16_RS09925	COG1484	DNA-dependent DNA replication
MTX16_RS09930	COG3611	Membrane attachment protein
MTX16_RS09940	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MTX16_RS09945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MTX16_RS09955	COG1971	Probably functions as a manganese efflux pump
MTX16_RS09965	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MTX16_RS09965	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MTX16_RS09970	COG5002	protein histidine kinase activity
MTX16_RS09975	COG0745	RESPONSE REGULATOR receiver
MTX16_RS09990	COG0538	isocitrate dehydrogenase activity
MTX16_RS09995	COG0372	Belongs to the citrate synthase family
MTX16_RS10005	COG0628	permease
MTX16_RS10010	COG3030	protein affecting phage T7 exclusion by the F plasmid
MTX16_RS10035	COG1725	Transcriptional regulator
MTX16_RS10040	COG0281	malic enzyme
MTX16_RS10045	COG0587	DNA-directed DNA polymerase activity
MTX16_RS10060	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MTX16_RS10075	COG4109	DRTGG domain
MTX16_RS10090	COG0006	proline dipeptidase activity
MTX16_RS10130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS10135	COG0662	Cupin 2, conserved barrel domain protein
MTX16_RS10150	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS10155	COG0589	response to stress
MTX16_RS10195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTX16_RS10220	COG0827	DNA restriction-modification system
MTX16_RS10225	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MTX16_RS10230	COG3874	Sporulation protein YtfJ
MTX16_RS10245	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MTX16_RS10255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MTX16_RS10270	COG1104	cysteine desulfurase activity
MTX16_RS10280	COG0583	DNA-binding transcription factor activity
MTX16_RS10285	COG0697	spore germination
MTX16_RS10290	COG1309	transcriptional regulator
MTX16_RS10295	COG1956	GAF domain-containing protein
MTX16_RS10300	COG0626	cystathionine gamma-synthase activity
MTX16_RS10360	COG1595	DNA-templated transcription, initiation
MTX16_RS10370	COG0110	maltose O-acetyltransferase activity
MTX16_RS10375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MTX16_RS10380	COG0454	-acetyltransferase
MTX16_RS10385	COG0517	IMP dehydrogenase activity
MTX16_RS10390	COG0123	including yeast histone deacetylase and acetoin utilization protein
MTX16_RS10405	COG0745	RESPONSE REGULATOR receiver
MTX16_RS10410	COG5002	protein histidine kinase activity
MTX16_RS10415	COG0666	response to abiotic stimulus
MTX16_RS10450	COG1609	Transcriptional regulator
MTX16_RS10455	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MTX16_RS10455	COG1605	Chorismate mutase
MTX16_RS10460	COG4851	CamS sex pheromone cAM373 precursor
MTX16_RS10465	COG3118	belongs to the thioredoxin family
MTX16_RS10475	COG2309	aminopeptidase activity
MTX16_RS10500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS10505	COG0697	spore germination
MTX16_RS10510	COG0789	Transcriptional regulator
MTX16_RS10525	COG1674	ftsk spoiiie
MTX16_RS10530	COG1388	LysM domain
MTX16_RS10530	COG0860	N-Acetylmuramoyl-L-alanine amidase
MTX16_RS10540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MTX16_RS10550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MTX16_RS10555	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
MTX16_RS10560	COG1363	Peptidase, m42
MTX16_RS10570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTX16_RS10585	COG0510	thiamine kinase activity
MTX16_RS10590	COG1523	belongs to the glycosyl hydrolase 13 family
MTX16_RS10600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MTX16_RS10605	COG1349	DNA-binding transcription factor activity
MTX16_RS10610	COG1187	pseudouridine synthase activity
MTX16_RS10615	COG2244	polysaccharide biosynthetic process
MTX16_RS10620	COG2081	HI0933 family
MTX16_RS10625	COG2814	Major facilitator Superfamily
MTX16_RS10635	COG3832	glyoxalase III activity
MTX16_RS10655	COG1329	Transcriptional regulator
MTX16_RS10680	COG0314	molybdopterin synthase activity
MTX16_RS10685	COG1763	Mo-molybdopterin cofactor biosynthetic process
MTX16_RS10690	COG0303	'Molybdopterin
MTX16_RS10700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MTX16_RS10705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MTX16_RS10725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MTX16_RS10735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MTX16_RS10775	COG2814	Major facilitator Superfamily
MTX16_RS10780	COG0475	glutathione-regulated potassium exporter activity
MTX16_RS10785	COG0490	domain, Protein
MTX16_RS10790	COG0582	viral genome integration into host DNA
MTX16_RS10800	COG1136	(ABC) transporter
MTX16_RS10820	COG1242	4 iron, 4 sulfur cluster binding
MTX16_RS10825	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MTX16_RS10840	COG1794	racemase activity, acting on amino acids and derivatives
MTX16_RS10860	COG2267	carboxylic ester hydrolase activity
MTX16_RS10865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MTX16_RS10870	COG0671	phosphoesterase, PA-phosphatase related
MTX16_RS10875	COG0438	transferase activity, transferring glycosyl groups
MTX16_RS10895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS10940	COG5002	protein histidine kinase activity
MTX16_RS10945	COG3852	Histidine kinase
MTX16_RS10950	COG0753	catalase activity
MTX16_RS10960	COG2267	carboxylic ester hydrolase activity
MTX16_RS10965	COG1368	sulfuric ester hydrolase activity
MTX16_RS10990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MTX16_RS10995	COG1116	anion transmembrane transporter activity
MTX16_RS11000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTX16_RS11025	COG0494	nUDIX hydrolase
MTX16_RS11055	COG1854	S-ribosylhomocysteine lyase activity
MTX16_RS11065	COG0288	reversible hydration of carbon dioxide
MTX16_RS11070	COG1271	oxidase subunit
MTX16_RS11075	COG1294	oxidase, subunit
MTX16_RS11090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTX16_RS11110	COG1842	Phage shock protein A
MTX16_RS11140	COG5002	protein histidine kinase activity
MTX16_RS11145	COG0745	RESPONSE REGULATOR receiver
MTX16_RS11170	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MTX16_RS11175	COG1597	lipid kinase activity
MTX16_RS11235	COG0586	Pfam SNARE associated Golgi protein
MTX16_RS11245	COG0577	efflux transmembrane transporter activity
MTX16_RS11250	COG1136	(ABC) transporter
MTX16_RS11255	COG3708	Transcriptional regulator
MTX16_RS11255	COG2207	Transcriptional regulator
MTX16_RS11265	COG1131	(ABC) transporter
MTX16_RS11270	COG5658	integral membrane protein
MTX16_RS11275	COG0640	Transcriptional regulator
MTX16_RS11280	COG0745	RESPONSE REGULATOR receiver
MTX16_RS11285	COG2205	protein histidine kinase activity
MTX16_RS11290	COG0577	efflux transmembrane transporter activity
MTX16_RS11295	COG0577	efflux transmembrane transporter activity
MTX16_RS11300	COG1136	(ABC) transporter
MTX16_RS11305	COG0577	efflux transmembrane transporter activity
MTX16_RS11330	COG2188	Transcriptional regulator
MTX16_RS11350	COG3964	amidohydrolase
MTX16_RS11370	COG4948	Mandelate Racemase Muconate Lactonizing
MTX16_RS11380	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MTX16_RS11385	COG0596	Alpha beta hydrolase
MTX16_RS11395	COG1169	isochorismate synthase
MTX16_RS11400	COG1575	Belongs to the MenA family. Type 1 subfamily
MTX16_RS11405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MTX16_RS11430	COG0058	SHG alpha-glucan phosphorylase activity
MTX16_RS11440	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MTX16_RS11560	COG0544	peptidyl-prolyl cis-trans isomerase activity
MTX16_RS11595	COG1285	pathogenesis
MTX16_RS11600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MTX16_RS11615	COG2155	Conserved Protein
MTX16_RS11620	COG1098	S1 RNA binding domain
MTX16_RS11625	COG0436	Aminotransferase
MTX16_RS11630	COG1522	sequence-specific DNA binding
MTX16_RS11635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MTX16_RS11640	COG2267	carboxylic ester hydrolase activity
MTX16_RS11650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MTX16_RS11670	COG5018	Exonuclease
MTX16_RS11675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MTX16_RS11695	COG2050	protein possibly involved in aromatic compounds catabolism
MTX16_RS11705	COG1268	BioY protein
MTX16_RS11725	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MTX16_RS11730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MTX16_RS11745	COG3584	3D domain protein
MTX16_RS11760	COG1252	NADH dehydrogenase
MTX16_RS11775	COG3708	Transcriptional regulator
MTX16_RS11790	COG1683	Conserved Protein
MTX16_RS11800	COG0316	Belongs to the HesB IscA family
MTX16_RS11815	COG1252	NADH dehydrogenase
MTX16_RS11825	COG2274	protein secretion by the type I secretion system
MTX16_RS11830	COG0390	transport system, permease component
MTX16_RS11840	COG2824	Alkylphosphonate utilization operon protein PhnA
MTX16_RS11890	COG4837	Protein of unknown function (DUF1462)
MTX16_RS11895	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MTX16_RS11905	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MTX16_RS11910	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MTX16_RS11920	COG2249	NAD(P)H dehydrogenase (quinone) activity
MTX16_RS11925	COG0647	UMP catabolic process
MTX16_RS11935	COG2445	Protein of unknown function DUF86
MTX16_RS11940	COG1494	fructose-1,6-bisphosphatase
MTX16_RS11955	COG4470	Protein conserved in bacteria
MTX16_RS11965	COG0789	Transcriptional regulator
MTX16_RS11970	COG4377	Putative membrane peptidase family (DUF2324)
MTX16_RS11995	COG0739	heme binding
MTX16_RS12005	COG3377	Domain of unknown function (DUF1805)
MTX16_RS12010	COG0737	Belongs to the 5'-nucleotidase family
MTX16_RS12015	COG0719	Fe-S assembly protein
MTX16_RS12020	COG0822	iron-sulfur transferase activity
MTX16_RS12025	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MTX16_RS12030	COG0719	Fe-S assembly protein
MTX16_RS12035	COG0396	ATPase activity
MTX16_RS12040	COG1464	Belongs to the NlpA lipoprotein family
MTX16_RS12045	COG1464	Belongs to the NlpA lipoprotein family
MTX16_RS12050	COG2011	ABC-type metal ion transport system permease component
MTX16_RS12065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MTX16_RS12070	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MTX16_RS12080	COG1393	Belongs to the ArsC family
MTX16_RS12100	COG0039	L-malate dehydrogenase activity
MTX16_RS12120	COG1309	transcriptional regulator
MTX16_RS12125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTX16_RS12130	COG1960	acyl-CoA dehydrogenase activity
MTX16_RS12135	COG0183	Belongs to the thiolase family
MTX16_RS12140	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTX16_RS12140	COG1024	Enoyl-CoA hydratase
MTX16_RS12150	COG1686	Belongs to the peptidase S11 family
MTX16_RS12165	COG0011	TIGRFAM Protein of
MTX16_RS12170	COG0840	transmembrane signaling receptor activity
MTX16_RS12185	COG2814	Major facilitator Superfamily
MTX16_RS12190	COG0531	amino acid
MTX16_RS12215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTX16_RS12250	COG0586	Pfam SNARE associated Golgi protein
MTX16_RS12260	COG1376	ErfK ybiS ycfS ynhG family protein
MTX16_RS12265	COG0745	RESPONSE REGULATOR receiver
MTX16_RS12270	COG5002	protein histidine kinase activity
MTX16_RS12300	COG0840	transmembrane signaling receptor activity
MTX16_RS12305	COG2151	metal-sulfur cluster biosynthetic enzyme
MTX16_RS12310	COG3227	Zinc metalloprotease (Elastase)
MTX16_RS12330	COG0475	glutathione-regulated potassium exporter activity
MTX16_RS12335	COG0490	domain, Protein
MTX16_RS12340	COG1115	amino acid carrier protein
MTX16_RS12345	COG0783	Belongs to the Dps family
MTX16_RS12360	COG1611	Belongs to the LOG family
MTX16_RS12370	COG1528	Iron-storage protein
MTX16_RS12380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MTX16_RS12385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MTX16_RS12390	COG1115	amino acid carrier protein
MTX16_RS12395	COG1115	amino acid carrier protein
MTX16_RS12400	COG2910	NAD(P)H-binding
MTX16_RS12415	COG0656	L-ascorbic acid biosynthetic process
MTX16_RS12420	COG2814	Major facilitator Superfamily
MTX16_RS12425	COG1733	regulation of RNA biosynthetic process
MTX16_RS12435	COG1252	NADH dehydrogenase
MTX16_RS12440	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MTX16_RS12525	COG1335	isochorismatase
MTX16_RS12575	COG0557	exoribonuclease II activity
MTX16_RS12580	COG1647	Serine aminopeptidase, S33
MTX16_RS12585	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MTX16_RS12590	COG1346	cytolysis
MTX16_RS12625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MTX16_RS12640	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MTX16_RS12650	COG1668	transmembrane transport
MTX16_RS12655	COG4152	abc transporter atp-binding protein
MTX16_RS12660	COG4585	Histidine kinase
MTX16_RS12690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MTX16_RS12705	COG2323	membrane
MTX16_RS12715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MTX16_RS12725	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MTX16_RS12735	COG1051	belongs to the nudix hydrolase family
MTX16_RS12745	COG0492	ferredoxin-NADP+ reductase activity
MTX16_RS12750	COG0457	Tetratricopeptide repeat
MTX16_RS12755	COG0110	maltose O-acetyltransferase activity
MTX16_RS12775	COG1950	PFAM Membrane protein of
MTX16_RS12780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MTX16_RS12785	COG0556	nucleotide-excision repair
MTX16_RS12800	COG0789	Transcriptional regulator
MTX16_RS12830	COG0583	DNA-binding transcription factor activity
MTX16_RS12840	COG0655	NAD(P)H dehydrogenase (quinone) activity
MTX16_RS12845	COG0488	(ABC) transporter
MTX16_RS12855	COG1132	(ABC) transporter
MTX16_RS12860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MTX16_RS12865	COG0793	Belongs to the peptidase S41A family
MTX16_RS12865	COG3409	Peptidoglycan-binding domain 1 protein
MTX16_RS12870	COG2177	Part of the ABC transporter FtsEX involved in
MTX16_RS12875	COG2884	Cell division ATP-binding protein ftsE
MTX16_RS12900	COG1131	(ABC) transporter
MTX16_RS12930	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MTX16_RS12935	COG1278	Cold shock
MTX16_RS12940	COG1040	competence protein
MTX16_RS12945	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MTX16_RS12950	COG1388	LysM domain
MTX16_RS12950	COG0791	NLP P60 protein
MTX16_RS12955	COG1733	regulation of RNA biosynthetic process
MTX16_RS12960	COG1307	EDD domain protein, DegV family
MTX16_RS12965	COG1739	Uncharacterized protein family UPF0029
MTX16_RS12970	COG1316	TRANSCRIPTIONal
MTX16_RS12975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MTX16_RS12980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MTX16_RS12985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MTX16_RS12995	COG3933	PFAM sigma-54 factor interaction domain-containing protein
MTX16_RS12995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MTX16_RS13015	COG1486	melibiose metabolic process
MTX16_RS13020	COG1447	Phosphotransferase system cellobiose-specific component IIA
MTX16_RS13025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MTX16_RS13035	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MTX16_RS13045	COG1447	Phosphotransferase system cellobiose-specific component IIA
MTX16_RS13055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MTX16_RS13060	COG1301	dicarboxylic acid transport
MTX16_RS13075	COG1511	domain protein
MTX16_RS13080	COG0583	DNA-binding transcription factor activity
MTX16_RS13085	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MTX16_RS13095	COG1271	oxidase subunit
MTX16_RS13100	COG1294	oxidase, subunit
MTX16_RS13105	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MTX16_RS13115	COG1620	l-lactate permease
MTX16_RS13125	COG2389	metal-binding protein
MTX16_RS13135	COG1368	sulfuric ester hydrolase activity
MTX16_RS13145	COG0791	NLP P60 protein
MTX16_RS13145	COG1388	LysM domain
MTX16_RS13150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MTX16_RS13160	COG1215	transferase activity, transferring glycosyl groups
MTX16_RS13165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MTX16_RS13170	COG3584	3D domain protein
MTX16_RS13170	COG1388	LysM domain
MTX16_RS13195	COG4715	Zinc finger, swim domain protein
MTX16_RS13200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MTX16_RS13240	COG0577	efflux transmembrane transporter activity
MTX16_RS13245	COG1136	(ABC) transporter
MTX16_RS13270	COG5002	protein histidine kinase activity
MTX16_RS13275	COG0745	RESPONSE REGULATOR receiver
MTX16_RS13285	COG1316	TRANSCRIPTIONal
MTX16_RS13320	COG1216	Glycosyl transferase, family 2
MTX16_RS13335	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MTX16_RS13350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MTX16_RS13355	COG1086	Polysaccharide biosynthesis protein
MTX16_RS13360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MTX16_RS13365	COG4464	protein tyrosine phosphatase activity
MTX16_RS13370	COG0489	protein tyrosine kinase activity
MTX16_RS13375	COG3944	biosynthesis protein
MTX16_RS13380	COG0489	protein tyrosine kinase activity
MTX16_RS13395	COG1609	Transcriptional regulator
MTX16_RS13405	COG0739	heme binding
MTX16_RS13420	COG3279	Response regulator of the LytR AlgR family
MTX16_RS13425	COG2385	sporulation resulting in formation of a cellular spore
MTX16_RS13440	COG4836	Membrane
MTX16_RS13445	COG1007	ATP synthesis coupled electron transport
MTX16_RS13450	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MTX16_RS13455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MTX16_RS13465	COG0839	Belongs to the complex I subunit 6 family
MTX16_RS13485	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MTX16_RS13500	COG3300	MHYT domain
MTX16_RS13500	COG5001	Diguanylate cyclase
MTX16_RS13550	COG0356	it plays a direct role in the translocation of protons across the membrane
MTX16_RS13585	COG0698	ribose 5-phosphate isomerase
MTX16_RS13600	COG2259	Doxx family
MTX16_RS13605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MTX16_RS13620	COG0009	L-threonylcarbamoyladenylate synthase
MTX16_RS13655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MTX16_RS13660	COG1494	fructose-1,6-bisphosphatase
MTX16_RS13680	COG4821	SIS domain
MTX16_RS13700	COG1960	acyl-CoA dehydrogenase activity
MTX16_RS13705	COG1960	acyl-CoA dehydrogenase activity
MTX16_RS13710	COG1250	3-hydroxyacyl-CoA dehydrogenase
MTX16_RS13715	COG0183	Belongs to the thiolase family
MTX16_RS13720	COG0247	lactate metabolic process
MTX16_RS13720	COG2181	nitrate reductase activity
MTX16_RS13725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MTX16_RS13735	COG5001	Diguanylate cyclase
MTX16_RS13735	COG3300	MHYT domain
MTX16_RS13750	COG3227	Zinc metalloprotease (Elastase)
MTX16_RS13755	COG2197	response regulator
MTX16_RS13760	COG4585	Histidine kinase
MTX16_RS13765	COG0842	Transport permease protein
MTX16_RS13770	COG1131	(ABC) transporter
MTX16_RS13775	COG0024	Methionine aminopeptidase
MTX16_RS13785	COG2234	aminopeptidase activity
MTX16_RS13810	COG4506	Protein conserved in bacteria
MTX16_RS13815	COG1619	proteins homologs of microcin C7 resistance protein MccF
MTX16_RS13840	COG2814	Major facilitator Superfamily
MTX16_RS13845	COG0789	Transcriptional regulator
MTX16_RS13850	COG0584	glycerophosphoryl diester phosphodiesterase
MTX16_RS13855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MTX16_RS13865	COG1994	Peptidase M50
MTX16_RS13875	COG1078	dGTPase activity
MTX16_RS13880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTX16_RS13885	COG1120	ATPase activity
MTX16_RS13890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTX16_RS13895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTX16_RS13915	COG0280	phosphate acetyltransferase
MTX16_RS13930	COG3773	Cell wall hydrolase
MTX16_RS13940	COG2363	Small membrane protein
MTX16_RS13950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MTX16_RS13955	COG2233	PERMEase
MTX16_RS13960	COG0561	phosphatase activity
MTX16_RS13965	COG2814	Major facilitator Superfamily
MTX16_RS13975	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MTX16_RS13980	COG1131	(ABC) transporter
MTX16_RS13985	COG2755	lipolytic protein G-D-S-L family
MTX16_RS13990	COG1609	Transcriptional regulator
MTX16_RS14000	COG0460	homoserine dehydrogenase
MTX16_RS14010	COG2873	o-acetylhomoserine
MTX16_RS14020	COG1011	Hydrolase
MTX16_RS14025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MTX16_RS14035	COG2197	response regulator
MTX16_RS14040	COG2203	Gaf domain
MTX16_RS14040	COG4585	Histidine kinase
MTX16_RS14045	COG0351	phosphomethylpyrimidine kinase
MTX16_RS14050	COG3706	GGDEF domain
MTX16_RS14055	COG2879	small protein
MTX16_RS14060	COG1966	Carbon starvation protein
MTX16_RS14065	COG3279	Response regulator of the LytR AlgR family
MTX16_RS14070	COG0477	Major facilitator Superfamily
MTX16_RS14080	COG0438	transferase activity, transferring glycosyl groups
MTX16_RS14095	COG0840	transmembrane signaling receptor activity
MTX16_RS14105	COG1607	acyl-coa hydrolase
MTX16_RS14110	COG1216	Glycosyl transferase, family 2
MTX16_RS14125	COG1216	Glycosyl transferase, family 2
MTX16_RS14135	COG4485	Bacterial membrane protein, YfhO
MTX16_RS14140	COG0463	Glycosyl transferase, family 2
MTX16_RS14145	COG0488	(ABC) transporter
MTX16_RS14150	COG1309	transcriptional regulator
MTX16_RS14155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MTX16_RS14160	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MTX16_RS14170	COG0628	permease
MTX16_RS14195	COG2814	Major facilitator Superfamily
MTX16_RS14200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MTX16_RS14205	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MTX16_RS14225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MTX16_RS14230	COG1272	protein, Hemolysin III
MTX16_RS14250	COG1164	Oligoendopeptidase f
MTX16_RS14295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MTX16_RS14300	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MTX16_RS14305	COG4853	Protein conserved in bacteria
MTX16_RS14315	COG5002	protein histidine kinase activity
MTX16_RS14320	COG0745	RESPONSE REGULATOR receiver
MTX16_RS14350	COG0305	Participates in initiation and elongation during chromosome replication
MTX16_RS14360	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MTX16_RS14365	COG4241	membrane
MTX16_RS14385	COG0012	GTP binding
MTX16_RS14390	COG4481	Protein conserved in bacteria
MTX16_RS14395	COG0668	transmembrane transport
MTX16_RS14405	COG1475	DNA binding
MTX16_RS14410	COG1192	Involved in chromosome partitioning
MTX16_RS14435	COG1847	R3H domain protein
MTX16_RS14450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MTX16_RS14460	COG0592	DNA-directed DNA polymerase activity
MTX16_RS14465	COG2501	S4 domain
MTX16_RS14475	COG0187	DNA topoisomerase II activity
MTX16_RS14480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MTX16_RS14515	COG0516	GMP reductase activity
MTX16_RS14515	COG0517	IMP dehydrogenase activity
MTX16_RS14520	COG1686	Belongs to the peptidase S11 family
MTX16_RS14550	COG1428	Deoxynucleoside kinase
MTX16_RS14555	COG1428	Deoxynucleoside kinase
MTX16_RS14560	COG1335	isochorismatase
MTX16_RS14565	COG0590	tRNA wobble adenosine to inosine editing
MTX16_RS14575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MTX16_RS14630	COG1982	Orn Lys Arg decarboxylase major
MTX16_RS14640	COG0470	DNA polymerase III
MTX16_RS14645	COG1774	PSP1 C-terminal conserved region
MTX16_RS14655	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MTX16_RS14665	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MTX16_RS14670	COG2002	toxin-antitoxin pair type II binding
MTX16_RS14680	COG0084	hydrolase, TatD family'
MTX16_RS14700	COG4466	Protein conserved in bacteria
MTX16_RS14715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MTX16_RS14720	COG0251	oxidation-reduction process
MTX16_RS14750	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MTX16_RS14755	COG2002	toxin-antitoxin pair type II binding
MTX16_RS14760	COG2244	polysaccharide biosynthetic process
MTX16_RS14765	COG3956	TIGRFAM MazG family protein
MTX16_RS14770	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MTX16_RS14790	COG1098	S1 RNA binding domain
MTX16_RS14805	COG2208	phosphoserine phosphatase activity
MTX16_RS14815	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MTX16_RS14820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MTX16_RS14835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MTX16_RS14840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MTX16_RS14845	COG0512	Glutamine amidotransferase of anthranilate synthase
MTX16_RS14850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MTX16_RS14855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MTX16_RS14860	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MTX16_RS14865	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MTX16_RS14870	COG1396	sequence-specific DNA binding
MTX16_RS14875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MTX16_RS14915	COG0544	peptidyl-prolyl cis-trans isomerase activity
MTX16_RS14965	COG3880	PFAM UvrB UvrC protein
MTX16_RS14975	COG0542	response to heat
MTX16_RS14980	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MTX16_RS14990	COG4956	integral membrane protein (PIN domain superfamily)
MTX16_RS15010	COG1045	serine acetyltransferase
MTX16_RS15025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MTX16_RS15030	COG3688	RNA-binding protein containing a PIN domain
MTX16_RS15045	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MTX16_RS15050	COG0250	Participates in transcription elongation, termination and antitermination
MTX16_RS15055	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MTX16_RS15075	COG2813	Specifically methylates the guanine in position
MTX16_RS15090	COG1358	cellular component organization or biogenesis
MTX16_RS15095	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MTX16_RS15160	COG0255	Belongs to the universal ribosomal protein uL29 family
MTX16_RS15220	COG0201	protein transport
MTX16_RS15230	COG0024	Methionine aminopeptidase
MTX16_RS15240	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MTX16_RS15275	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MTX16_RS15300	COG0860	N-Acetylmuramoyl-L-alanine amidase
MTX16_RS15305	COG0489	protein tyrosine kinase activity
MTX16_RS15315	COG2194	sulfuric ester hydrolase activity
MTX16_RS15320	COG0726	polysaccharide deacetylase
MTX16_RS15400	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MTX16_RS15405	COG4856	YbbR-like protein
MTX16_RS15445	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS15450	COG2011	ABC-type metal ion transport system permease component
MTX16_RS15455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MTX16_RS15460	COG1464	Belongs to the NlpA lipoprotein family
MTX16_RS15465	COG0604	alcohol dehydrogenase
MTX16_RS15475	COG0277	FAD linked oxidase domain protein
MTX16_RS15480	COG2271	Major facilitator Superfamily
MTX16_RS15490	COG2814	Major facilitator Superfamily
MTX16_RS15505	COG2207	Transcriptional regulator
MTX16_RS15520	COG4166	transmembrane transport
MTX16_RS15525	COG4166	transmembrane transport
MTX16_RS15530	COG0656	L-ascorbic acid biosynthetic process
MTX16_RS15545	COG4149	molybdate abc transporter
MTX16_RS15550	COG0725	ABC transporter, periplasmic molybdate-binding protein
MTX16_RS15555	COG1910	domain protein
MTX16_RS15570	COG0697	spore germination
MTX16_RS15585	COG0204	Acyl-transferase
MTX16_RS15595	COG1609	Transcriptional regulator
MTX16_RS15605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTX16_RS15620	COG5298	Protein conserved in bacteria
MTX16_RS15645	COG0488	(ABC) transporter
MTX16_RS15655	COG0747	negative chemotaxis
MTX16_RS15660	COG0601	transmembrane transport
MTX16_RS15665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTX16_RS15670	COG0444	Belongs to the ABC transporter superfamily
MTX16_RS15675	COG4608	Belongs to the ABC transporter superfamily
MTX16_RS15680	COG0561	phosphatase activity
MTX16_RS15710	COG3185	4-Hydroxyphenylpyruvate dioxygenase
MTX16_RS15715	COG0179	Fumarylacetoacetate (FAA) hydrolase
MTX16_RS15725	COG0531	amino acid
MTX16_RS15730	COG2814	Major facilitator Superfamily
MTX16_RS15740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MTX16_RS15750	COG4294	response to UV
MTX16_RS15755	COG0705	Rhomboid family
MTX16_RS15765	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MTX16_RS15770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MTX16_RS15775	COG0864	Transcriptional regulator
MTX16_RS15780	COG2337	Toxic component of a toxin-antitoxin (TA) module
MTX16_RS15785	COG2183	response to ionizing radiation
MTX16_RS15885	COG0802	atpase or kinase
MTX16_RS15890	COG1214	PFAM Peptidase M22, glycoprotease
MTX16_RS15895	COG0456	acetyltransferase
MTX16_RS15905	COG0488	(ABC) transporter
MTX16_RS15920	COG1266	CAAX protease self-immunity
MTX16_RS15940	COG2252	PERMEase
MTX16_RS15950	COG5002	protein histidine kinase activity
MTX16_RS15975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MTX16_RS16015	COG2205	protein histidine kinase activity
MTX16_RS16020	COG0745	RESPONSE REGULATOR receiver
MTX16_RS16060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MTX16_RS16070	COG1215	transferase activity, transferring glycosyl groups
MTX16_RS16090	COG0697	spore germination
MTX16_RS16120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MTX16_RS16125	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MTX16_RS16130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MTX16_RS16140	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MTX16_RS16155	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MTX16_RS16165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MTX16_RS16175	COG0151	Belongs to the GarS family
MTX16_RS16200	COG0210	DNA helicase
MTX16_RS16210	COG4851	CamS sex pheromone cAM373 precursor
MTX16_RS16225	COG1335	isochorismatase
MTX16_RS16235	COG2011	ABC-type metal ion transport system permease component
MTX16_RS16240	COG1464	Belongs to the NlpA lipoprotein family
MTX16_RS16255	COG0003	Pfam Anion-transporting ATPase
MTX16_RS16260	COG1846	Transcriptional regulator
MTX16_RS16265	COG4682	membrane
MTX16_RS16285	COG1597	lipid kinase activity
MTX16_RS16295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MTX16_RS16305	COG1012	belongs to the aldehyde dehydrogenase family
MTX16_RS16310	COG2076	Multidrug Resistance protein
MTX16_RS16320	COG2309	aminopeptidase activity
MTX16_RS16340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MTX16_RS16350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MTX16_RS16355	COG4807	Protein conserved in bacteria
MTX16_RS16380	COG1757	Na H antiporter
MTX16_RS16385	COG1473	amidohydrolase
MTX16_RS16400	COG0450	alkyl hydroperoxide reductase
MTX16_RS16420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTX16_RS16425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTX16_RS16430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTX16_RS16435	COG0492	ferredoxin-NADP+ reductase activity
MTX16_RS16445	COG0166	Belongs to the GPI family
MTX16_RS16470	COG5002	protein histidine kinase activity
MTX16_RS16490	COG3541	Predicted nucleotidyltransferase
MTX16_RS16500	COG2814	Major facilitator Superfamily
MTX16_RS16505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTX16_RS16505	COG0723	plastoquinol--plastocyanin reductase activity
MTX16_RS16515	COG0765	amino acid transport
MTX16_RS16520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTX16_RS16525	COG1126	abc transporter atp-binding protein
MTX16_RS16530	COG0840	transmembrane signaling receptor activity
MTX16_RS16555	COG0549	Belongs to the carbamate kinase family
MTX16_RS16560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MTX16_RS16570	COG0277	FAD linked oxidase domain protein
MTX16_RS16575	COG0366	Alpha amylase catalytic
MTX16_RS16580	COG1263	PTS System
MTX16_RS16580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTX16_RS16580	COG2190	(PTS) system
MTX16_RS16610	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MTX16_RS16630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTX16_RS16635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MTX16_RS16640	COG1116	anion transmembrane transporter activity
MTX16_RS16690	COG2270	Major facilitator Superfamily
MTX16_RS16720	COG2310	stress, protein
MTX16_RS16725	COG2310	stress, protein
MTX16_RS16730	COG2310	stress, protein
MTX16_RS16735	COG0861	Integral membrane protein TerC family
MTX16_RS16745	COG3853	Toxic anion resistance protein (TelA)
MTX16_RS16760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MTX16_RS16770	COG1295	ribonuclease BN
MTX16_RS16775	COG2217	Heavy metal translocating P-type atpase
MTX16_RS16780	COG0697	spore germination
MTX16_RS16800	COG0586	Pfam SNARE associated Golgi protein
MTX16_RS16815	COG3871	stress protein (general stress protein 26)
MTX16_RS16820	COG0387	Pfam Sodium calcium exchanger
MTX16_RS16830	COG0535	radical SAM domain protein
MTX16_RS16850	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MTX16_RS16855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MTX16_RS16870	COG3829	transcription factor binding
MTX16_RS16880	COG0833	amino acid
MTX16_RS16885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MTX16_RS16915	COG1263	PTS System
MTX16_RS16915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTX16_RS16920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MTX16_RS16935	COG0463	Glycosyl transferase, family 2
MTX16_RS16945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MTX16_RS16945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MTX16_RS16950	COG0463	Glycosyl transferase, family 2
MTX16_RS16965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MTX16_RS16985	COG1228	amidohydrolase
MTX16_RS16990	COG1090	epimerase
MTX16_RS17020	COG1988	membrane-bound metal-dependent
MTX16_RS17025	COG1194	a g-specific adenine glycosylase
MTX16_RS17050	COG1132	(ABC) transporter
MTX16_RS17055	COG4129	membrane
MTX16_RS17060	COG0070	glutamate synthase
MTX16_RS17060	COG0067	glutamate synthase
MTX16_RS17060	COG0069	glutamate synthase activity
MTX16_RS17070	COG4555	ABC transporter
MTX16_RS17090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MTX16_RS17095	COG0735	belongs to the Fur family
MTX16_RS17215	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MTX16_RS17240	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MTX16_RS17250	COG2766	serine protein kinase
MTX16_RS17270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MTX16_RS17280	COG1585	Membrane protein implicated in regulation of membrane protease activity
MTX16_RS17285	COG2268	Band 7 protein
MTX16_RS17295	COG3290	protein histidine kinase activity
MTX16_RS17300	COG4565	transcriptional regulatory protein
MTX16_RS17305	COG2851	Citrate transporter
MTX16_RS17330	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MTX16_RS17335	COG3842	ATPase activity
MTX16_RS17340	COG1175	transmembrane transport
MTX16_RS17345	COG0395	ABC-type sugar transport system, permease component
MTX16_RS17355	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MTX16_RS17360	COG0745	RESPONSE REGULATOR receiver
MTX16_RS17365	COG5002	protein histidine kinase activity
MTX16_RS17375	COG4990	cell redox homeostasis
MTX16_RS17385	COG3290	protein histidine kinase activity
MTX16_RS17390	COG4565	transcriptional regulatory protein
MTX16_RS17395	COG3493	citrate carrier protein
MTX16_RS17400	COG0281	malic enzyme
MTX16_RS17410	COG0697	spore germination
MTX16_RS17415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTX16_RS17425	COG5002	protein histidine kinase activity
MTX16_RS17435	COG0456	acetyltransferase
MTX16_RS17435	COG0454	-acetyltransferase
MTX16_RS17440	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MTX16_RS17445	COG3383	formate dehydrogenase (NAD+) activity
MTX16_RS17450	COG2427	Protein of unknown function (DUF1641)
MTX16_RS17465	COG0531	amino acid
MTX16_RS17470	COG0640	Transcriptional regulator
MTX16_RS17475	COG2217	Heavy metal translocating P-type atpase
MTX16_RS17485	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MTX16_RS17500	COG3227	Zinc metalloprotease (Elastase)
MTX16_RS17520	COG2720	vancomycin resistance protein
MTX16_RS17525	COG1316	TRANSCRIPTIONal
MTX16_RS17530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MTX16_RS17535	COG0346	lactoylglutathione lyase activity
MTX16_RS17540	COG1253	flavin adenine dinucleotide binding
MTX16_RS17545	COG1027	Aspartate ammonia-lyase
MTX16_RS17550	COG1620	l-lactate permease
MTX16_RS17565	COG3104	oligopeptide transport
MTX16_RS17570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTX16_RS17575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTX16_RS17580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTX16_RS17590	COG2226	methyltransferase
MTX16_RS17600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MTX16_RS17610	COG4548	von Willebrand factor, type A
MTX16_RS17615	COG0714	Associated with various cellular activities
MTX16_RS17635	COG0531	amino acid
MTX16_RS17640	COG2188	Transcriptional regulator
MTX16_RS17645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTX16_RS17645	COG1263	PTS System
MTX16_RS17650	COG0366	Alpha amylase catalytic
MTX16_RS17665	COG0697	spore germination
MTX16_RS17670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MTX16_RS17675	COG1115	amino acid carrier protein
MTX16_RS17680	COG1126	abc transporter atp-binding protein
MTX16_RS17685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTX16_RS17690	COG0765	amino acid transport
MTX16_RS17695	COG0765	amino acid transport
MTX16_RS17700	COG0833	amino acid
MTX16_RS17725	COG2378	regulation of single-species biofilm formation
MTX16_RS17730	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MTX16_RS17735	COG5002	protein histidine kinase activity
MTX16_RS17750	COG0659	secondary active sulfate transmembrane transporter activity
MTX16_RS17765	COG2271	Major facilitator Superfamily
MTX16_RS17770	COG1846	Transcriptional regulator
MTX16_RS17775	COG0477	Major facilitator Superfamily
MTX16_RS17780	COG1609	Transcriptional regulator
MTX16_RS17785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MTX16_RS17800	COG1172	Belongs to the binding-protein-dependent transport system permease family
MTX16_RS17805	COG1879	ABC-type sugar transport system periplasmic component
MTX16_RS17830	COG1063	alcohol dehydrogenase
MTX16_RS17875	COG0840	transmembrane signaling receptor activity
MTX16_RS17880	COG1388	LysM domain
MTX16_RS17880	COG3584	3D domain protein
MTX16_RS17885	COG1476	TRANSCRIPTIONal
MTX16_RS17905	COG3104	oligopeptide transport
MTX16_RS17910	COG1114	Component of the transport system for branched-chain amino acids
MTX16_RS17925	COG1113	amino acid transport
MTX16_RS17930	COG2252	PERMEase
MTX16_RS17955	COG2153	protein acetylation
MTX16_RS17965	COG0475	glutathione-regulated potassium exporter activity
MTX16_RS17965	COG0569	domain protein
MTX16_RS17980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MTX16_RS17990	COG0833	amino acid
MTX16_RS17995	COG4990	cell redox homeostasis
MTX16_RS18010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MTX16_RS18015	COG0697	spore germination
MTX16_RS18020	COG0531	amino acid
MTX16_RS18030	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MTX16_RS18035	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MTX16_RS18040	COG1918	ferrous iron import across plasma membrane
MTX16_RS18040	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MTX16_RS18045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MTX16_RS18050	COG0573	inorganic phosphate transmembrane transporter activity
MTX16_RS18055	COG0581	inorganic phosphate transmembrane transporter activity
MTX16_RS18060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MTX16_RS18180	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MTX16_RS18200	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MTX16_RS18205	COG1116	anion transmembrane transporter activity
MTX16_RS18210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MTX16_RS18215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MTX16_RS18220	COG0352	thiamine-phosphate diphosphorylase activity
MTX16_RS18225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTX16_RS18230	COG2104	thiamine diphosphate biosynthetic process
MTX16_RS18240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MTX16_RS18245	COG0351	phosphomethylpyrimidine kinase
MTX16_RS18285	COG2205	protein histidine kinase activity
MTX16_RS18290	COG2814	Major facilitator Superfamily
MTX16_RS18295	COG1846	Transcriptional regulator
MTX16_RS18305	COG2252	PERMEase
MTX16_RS18310	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS18325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MTX16_RS18330	COG1621	beta-fructofuranosidase activity
MTX16_RS18335	COG1263	PTS System
MTX16_RS18335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTX16_RS18340	COG1609	Transcriptional regulator
MTX16_RS18390	COG0778	Nitroreductase
MTX16_RS18395	COG2719	SpoVR family
MTX16_RS18415	COG0446	pyridine nucleotide-disulphide oxidoreductase
MTX16_RS18420	COG1937	Protein conserved in bacteria
MTX16_RS18425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MTX16_RS18425	COG0425	Belongs to the sulfur carrier protein TusA family
MTX16_RS18430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MTX16_RS18430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTX16_RS18435	COG0425	Belongs to the sulfur carrier protein TusA family
MTX16_RS18440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MTX16_RS18440	COG0425	Belongs to the sulfur carrier protein TusA family
MTX16_RS18445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MTX16_RS18450	COG2210	Belongs to the sulfur carrier protein TusA family
MTX16_RS18455	COG0730	response to heat
MTX16_RS18465	COG1316	TRANSCRIPTIONal
MTX16_RS18470	COG0604	alcohol dehydrogenase
MTX16_RS18475	COG1283	sodium-dependent phosphate transmembrane transporter activity
MTX16_RS18490	COG3711	transcriptional antiterminator
MTX16_RS18490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MTX16_RS18495	COG1447	Phosphotransferase system cellobiose-specific component IIA
MTX16_RS18500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MTX16_RS18525	COG1388	LysM domain
MTX16_RS18525	COG3584	3D domain protein
MTX16_RS18530	COG0577	efflux transmembrane transporter activity
MTX16_RS18535	COG1136	(ABC) transporter
MTX16_RS18545	COG5522	Integral membrane protein (intg_mem_TP0381)
MTX16_RS18560	COG1114	Component of the transport system for branched-chain amino acids
MTX16_RS18565	COG3546	catalase activity
MTX16_RS18600	COG0586	Pfam SNARE associated Golgi protein
MTX16_RS18635	COG0531	amino acid
MTX16_RS18640	COG0475	glutathione-regulated potassium exporter activity
MTX16_RS18650	COG1737	Transcriptional regulator
MTX16_RS18660	COG1263	PTS System
MTX16_RS18660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTX16_RS18670	COG2259	Doxx family
MTX16_RS18690	COG1522	sequence-specific DNA binding
MTX16_RS18695	COG0165	Argininosuccinate lyase
MTX16_RS18695	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MTX16_RS18700	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS18720	COG1309	transcriptional regulator
MTX16_RS18725	COG2814	Major facilitator Superfamily
MTX16_RS18730	COG1733	regulation of RNA biosynthetic process
MTX16_RS18740	COG2249	NAD(P)H dehydrogenase (quinone) activity
MTX16_RS18745	COG4533	DNA binding
MTX16_RS18750	COG2211	Major facilitator Superfamily
MTX16_RS18765	COG0693	protein deglycase activity
MTX16_RS18770	COG0693	protein deglycase activity
MTX16_RS18770	COG0753	catalase activity
MTX16_RS18780	COG0531	amino acid
MTX16_RS18795	COG1012	belongs to the aldehyde dehydrogenase family
MTX16_RS18800	COG1132	(ABC) transporter
MTX16_RS18805	COG1132	(ABC) transporter
MTX16_RS18810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTX16_RS18815	COG0765	amino acid transport
MTX16_RS18820	COG1126	abc transporter atp-binding protein
MTX16_RS18835	COG0189	ligase activity
MTX16_RS18855	COG4585	Histidine kinase
MTX16_RS18860	COG2197	response regulator
MTX16_RS18865	COG0028	Belongs to the TPP enzyme family
MTX16_RS18870	COG3527	Alpha-acetolactate decarboxylase
MTX16_RS18880	COG0561	phosphatase activity
MTX16_RS18890	COG5632	N-Acetylmuramoyl-L-alanine amidase
MTX16_RS18890	COG3409	Peptidoglycan-binding domain 1 protein
MTX16_RS18895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MTX16_RS18915	COG0659	secondary active sulfate transmembrane transporter activity
MTX16_RS18920	COG2244	polysaccharide biosynthetic process
MTX16_RS18940	COG1024	Enoyl-CoA hydratase
MTX16_RS18960	COG1363	Peptidase, m42
MTX16_RS18995	COG0601	transmembrane transport
MTX16_RS19000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTX16_RS19005	COG0444	Belongs to the ABC transporter superfamily
MTX16_RS19010	COG4608	Belongs to the ABC transporter superfamily
MTX16_RS19020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTX16_RS19125	COG0477	Major facilitator Superfamily
MTX16_RS19130	COG3290	protein histidine kinase activity
MTX16_RS19135	COG4565	transcriptional regulatory protein
MTX16_RS19140	COG3181	Tripartite tricarboxylate transporter family receptor
MTX16_RS19190	COG0305	Participates in initiation and elongation during chromosome replication
MTX16_RS19220	COG0477	Major facilitator Superfamily
MTX16_RS19240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS19265	COG1073	alpha beta
MTX16_RS19295	COG1183	phosphatidylcholine synthase activity
MTX16_RS19310	COG2376	Dihydroxyacetone kinase
MTX16_RS19320	COG2376	Dihydroxyacetone kinase
MTX16_RS19350	COG0457	Tetratricopeptide repeat
MTX16_RS19375	COG1388	LysM domain
MTX16_RS19375	COG3584	3D domain protein
MTX16_RS19380	COG1388	LysM domain
MTX16_RS19380	COG0791	NLP P60 protein
MTX16_RS19390	COG2373	Large extracellular alpha-helical protein
MTX16_RS19435	COG3237	CsbD-like
MTX16_RS19460	COG1191	sigma factor activity
MTX16_RS19470	COG2208	phosphoserine phosphatase activity
MTX16_RS19475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MTX16_RS19480	COG0784	Response regulator, receiver
MTX16_RS19480	COG2205	protein histidine kinase activity
MTX16_RS19480	COG5002	protein histidine kinase activity
MTX16_RS19525	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MTX16_RS19545	COG0420	3'-5' exonuclease activity
MTX16_RS19550	COG4717	serine-type aminopeptidase activity
MTX16_RS19565	COG1280	lysine exporter protein (LysE YggA)
MTX16_RS19570	COG0346	lactoylglutathione lyase activity
MTX16_RS19575	COG0346	lactoylglutathione lyase activity
MTX16_RS19580	COG0457	Tetratricopeptide repeat
MTX16_RS19590	COG2267	carboxylic ester hydrolase activity
MTX16_RS19615	COG2140	Oxalate decarboxylase
MTX16_RS19620	COG3620	sequence-specific DNA binding
MTX16_RS19625	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MTX16_RS19630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MTX16_RS19640	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MTX16_RS19665	COG0772	Belongs to the SEDS family
MTX16_RS19670	COG3973	AAA domain
MTX16_RS19680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MTX16_RS19700	COG4980	gas vesicle protein
MTX16_RS19705	COG0537	adenosine 5'-monophosphoramidase activity
MTX16_RS19710	COG1131	(ABC) transporter
MTX16_RS19715	COG4473	ABC transporter
MTX16_RS19740	COG3402	PFAM membrane-flanked domain
MTX16_RS19745	COG3428	Bacterial PH domain
MTX16_RS19775	COG0697	spore germination
MTX16_RS19780	COG3402	PFAM membrane-flanked domain
MTX16_RS19785	COG3428	Bacterial PH domain
MTX16_RS19790	COG2329	Antibiotic biosynthesis monooxygenase
MTX16_RS19795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MTX16_RS19810	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MTX16_RS19845	COG1309	transcriptional regulator
MTX16_RS19850	COG1511	domain protein
MTX16_RS19870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS19880	COG2378	regulation of single-species biofilm formation
MTX16_RS19885	COG1609	Transcriptional regulator
MTX16_RS19895	COG1234	tRNA 3'-trailer cleavage
MTX16_RS19900	COG0095	Lipoate-protein ligase
MTX16_RS19910	COG0318	PFAM AMP-dependent synthetase and ligase
MTX16_RS20030	COG1408	metallophosphoesterase
MTX16_RS20035	COG1078	dGTPase activity
MTX16_RS20050	COG2207	Transcriptional regulator
MTX16_RS20050	COG3708	Transcriptional regulator
MTX16_RS20060	COG2205	protein histidine kinase activity
MTX16_RS20065	COG0745	RESPONSE REGULATOR receiver
MTX16_RS20085	COG0501	Belongs to the peptidase M48B family
MTX16_RS20090	COG0840	transmembrane signaling receptor activity
MTX16_RS20095	COG3693	PFAM glycoside hydrolase, family 10
MTX16_RS20105	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MTX16_RS20110	COG2224	Isocitrate lyase
MTX16_RS20150	COG0398	Pfam SNARE associated Golgi protein
MTX16_RS20210	COG0179	Fumarylacetoacetate (FAA) hydrolase
MTX16_RS20235	COG0367	asparagine synthase
MTX16_RS20245	COG0753	catalase activity
MTX16_RS20250	COG0004	ammonium transporteR
MTX16_RS20270	COG2996	Protein conserved in bacteria
MTX16_RS20285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTX16_RS20300	COG0561	phosphatase activity
MTX16_RS20320	COG2267	carboxylic ester hydrolase activity
MTX16_RS20340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MTX16_RS20345	COG5504	Zn-dependent protease
MTX16_RS20360	COG0180	Tryptophanyl-tRNA synthetase
MTX16_RS20370	COG4166	transmembrane transport
MTX16_RS20375	COG0601	transmembrane transport
MTX16_RS20380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTX16_RS20385	COG0444	Belongs to the ABC transporter superfamily
MTX16_RS20390	COG4608	Belongs to the ABC transporter superfamily
MTX16_RS20395	COG0534	Mate efflux family protein
MTX16_RS20400	COG4166	transmembrane transport
MTX16_RS20415	COG0861	Integral membrane protein TerC family
MTX16_RS20435	COG1164	Oligoendopeptidase f
MTX16_RS20450	COG2346	COG2346, Truncated hemoglobins
MTX16_RS20455	COG4116	CYTH
MTX16_RS20465	COG2357	RelA SpoT domain protein
MTX16_RS20475	COG0564	pseudouridine synthase activity
MTX16_RS20490	COG0772	Belongs to the SEDS family
MTX16_RS20495	COG1216	Glycosyl transferase, family 2
MTX16_RS20515	COG0463	Glycosyl transferase, family 2
MTX16_RS20515	COG0457	Tetratricopeptide repeat
MTX16_RS20535	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MTX16_RS20550	COG1091	dTDP-4-dehydrorhamnose reductase activity
MTX16_RS20595	COG2153	protein acetylation
MTX16_RS20605	COG2382	esterase
MTX16_RS20625	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MTX16_RS20635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MTX16_RS20635	COG0512	Glutamine amidotransferase of anthranilate synthase
MTX16_RS20670	COG1620	l-lactate permease
MTX16_RS20675	COG5634	Uncharacterized conserved protein (DUF2278)
MTX16_RS20710	COG2226	methyltransferase
MTX16_RS20730	COG0508	dehydrogenase complex catalyzes the overall conversion of
MTX16_RS20740	COG1476	TRANSCRIPTIONal
MTX16_RS20830	COG1686	Belongs to the peptidase S11 family
MTX16_RS20835	COG0681	Belongs to the peptidase S26 family
MTX16_RS20870	COG1012	belongs to the aldehyde dehydrogenase family
MTX16_RS20880	COG1176	ABC-type spermidine putrescine transport system, permease component I
MTX16_RS20885	COG1177	transmembrane transport
MTX16_RS20900	COG2409	Drug exporters of the RND superfamily
MTX16_RS20910	COG0564	pseudouridine synthase activity
MTX16_RS20920	COG2340	Cysteine-rich secretory protein family
MTX16_RS20925	COG0247	lactate metabolic process
MTX16_RS20930	COG0277	FAD linked oxidase domain protein
MTX16_RS20935	COG3835	regulator
MTX16_RS20945	COG0745	RESPONSE REGULATOR receiver
MTX16_RS20950	COG5002	protein histidine kinase activity
MTX16_RS20955	COG2186	Transcriptional regulator
MTX16_RS20975	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MTX16_RS20985	COG2116	formate transmembrane transporter activity
MTX16_RS20990	COG0861	Integral membrane protein TerC family
MTX16_RS20995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MTX16_RS21005	COG2030	dehydratase
MTX16_RS21025	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS21030	COG3243	poly(R)-hydroxyalkanoic acid synthase
MTX16_RS21040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MTX16_RS21055	COG1840	ABC-type Fe3 transport system, periplasmic component
MTX16_RS21060	COG3842	ATPase activity
MTX16_RS21085	COG1349	DNA-binding transcription factor activity
MTX16_RS21095	COG0235	Class ii aldolase
MTX16_RS21105	COG2861	carbohydrate metabolic process
MTX16_RS21115	COG3852	Histidine kinase
MTX16_RS21120	COG1846	Transcriptional regulator
MTX16_RS21130	COG2318	DinB family
MTX16_RS21140	COG5002	protein histidine kinase activity
MTX16_RS21150	COG0720	synthase
MTX16_RS21165	COG4873	Protein conserved in bacteria
MTX16_RS21195	COG1780	Probably involved in ribonucleotide reductase function
MTX16_RS21230	COG1725	Transcriptional regulator
MTX16_RS21235	COG1131	(ABC) transporter
MTX16_RS21245	COG1131	(ABC) transporter
MTX16_RS21265	COG1522	sequence-specific DNA binding
MTX16_RS21275	COG1335	isochorismatase
MTX16_RS21285	COG1619	proteins homologs of microcin C7 resistance protein MccF
MTX16_RS21290	COG2070	2-Nitropropane dioxygenase
MTX16_RS21295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MTX16_RS21305	COG1696	Membrane protein involved in D-alanine export
MTX16_RS21330	COG0716	FMN binding
MTX16_RS21345	COG3173	Aminoglycoside phosphotransferase
MTX16_RS21390	COG1846	Transcriptional regulator
MTX16_RS21400	COG1301	dicarboxylic acid transport
MTX16_RS21405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MTX16_RS21410	COG4709	membrane
MTX16_RS21415	COG3874	Sporulation protein YtfJ
MTX16_RS21435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MTX16_RS21440	COG0028	Belongs to the TPP enzyme family
MTX16_RS21445	COG0440	acetolactate synthase activity
MTX16_RS21520	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MTX16_RS21535	COG1183	phosphatidylcholine synthase activity
MTX16_RS21540	COG1368	sulfuric ester hydrolase activity
MTX16_RS21550	COG0019	diaminopimelate decarboxylase activity
MTX16_RS21570	COG0529	Catalyzes the synthesis of activated sulfate
MTX16_RS21575	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MTX16_RS21595	COG1648	precorrin-2 dehydrogenase activity
MTX16_RS21600	COG0733	neurotransmitter:sodium symporter activity
MTX16_RS21625	COG1757	Na H antiporter
MTX16_RS21640	COG4758	membrane
MTX16_RS21645	COG4585	Histidine kinase
MTX16_RS21650	COG2197	response regulator
MTX16_RS21660	COG1114	Component of the transport system for branched-chain amino acids
MTX16_RS21715	COG0730	response to heat
MTX16_RS21720	COG0306	phosphate transporter
MTX16_RS21725	COG1392	Phosphate transport regulator
MTX16_RS21730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MTX16_RS21745	COG3852	Histidine kinase
MTX16_RS21750	COG1801	Protein of unknown function DUF72
MTX16_RS21760	COG0582	viral genome integration into host DNA
MTX16_RS21765	COG5002	protein histidine kinase activity
MTX16_RS21780	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MTX16_RS21780	COG0392	lysyltransferase activity
MTX16_RS21795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MTX16_RS21800	COG1686	Belongs to the peptidase S11 family
MTX16_RS21805	COG2715	membrane protein required for spore maturation
MTX16_RS21810	COG0700	Nucleoside recognition
MTX16_RS21815	COG1187	pseudouridine synthase activity
MTX16_RS21825	COG1333	cytochrome c biogenesis protein
MTX16_RS21830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MTX16_RS21835	COG0745	RESPONSE REGULATOR receiver
MTX16_RS21840	COG5002	protein histidine kinase activity
MTX16_RS21845	COG2096	Adenosyltransferase
MTX16_RS21860	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MTX16_RS21865	COG1141	Ferredoxin
MTX16_RS21875	COG0514	ATP-dependent DNA helicase (RecQ)
MTX16_RS21880	COG1266	CAAX protease self-immunity
MTX16_RS21890	COG1408	metallophosphoesterase
MTX16_RS21895	COG0789	Transcriptional regulator
MTX16_RS21905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MTX16_RS21925	COG0492	ferredoxin-NADP+ reductase activity
MTX16_RS21930	COG0252	asparaginase activity
MTX16_RS22000	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MTX16_RS22015	COG0142	geranyltranstransferase activity
MTX16_RS22025	COG0142	geranyltranstransferase activity
MTX16_RS22050	COG0457	Tetratricopeptide repeat
MTX16_RS22070	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MTX16_RS22075	COG2010	Cytochrome c
MTX16_RS22075	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MTX16_RS22080	COG4347	Protein of unknown function (DUF1405)
MTX16_RS22095	COG2738	Putative neutral zinc metallopeptidase
MTX16_RS22105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTX16_RS22110	COG1694	Mazg nucleotide pyrophosphohydrolase
MTX16_RS22130	COG0438	transferase activity, transferring glycosyl groups
MTX16_RS22165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MTX16_RS22165	COG1199	ATP-dependent helicase activity
MTX16_RS22185	COG3935	DnaD domain protein
MTX16_RS22190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MTX16_RS22200	COG4499	WXG100 protein secretion system (Wss), protein YukC
MTX16_RS22200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MTX16_RS22255	COG0116	Belongs to the methyltransferase superfamily
MTX16_RS22265	COG1199	ATP-dependent helicase activity
MTX16_RS22270	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MTX16_RS22280	COG0024	Methionine aminopeptidase
MTX16_RS22290	COG2233	PERMEase
MTX16_RS22295	COG2311	Membrane
MTX16_RS22300	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MTX16_RS22310	COG0456	acetyltransferase
MTX16_RS22360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MTX16_RS22375	COG3944	biosynthesis protein
MTX16_RS22385	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MTX16_RS22400	COG1215	transferase activity, transferring glycosyl groups
MTX16_RS22405	COG0438	transferase activity, transferring glycosyl groups
MTX16_RS22420	COG0454	-acetyltransferase
MTX16_RS22440	COG0328	RNA-DNA hybrid ribonuclease activity
MTX16_RS22475	COG3403	YqcI/YcgG family
MTX16_RS22480	COG1280	lysine exporter protein (LysE YggA)
MTX16_RS22500	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MTX16_RS22505	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MTX16_RS22515	COG0475	glutathione-regulated potassium exporter activity
MTX16_RS22520	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MTX16_RS22525	COG0789	Transcriptional regulator
MTX16_RS22525	COG4978	Transcriptional regulator
MTX16_RS22535	COG2323	membrane
MTX16_RS22540	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MTX16_RS22580	COG1923	regulation of RNA biosynthetic process
MTX16_RS22590	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MTX16_RS22595	COG1360	Flagellar Motor Protein
MTX16_RS22600	COG2201	protein-glutamate methylesterase activity
MTX16_RS22605	COG0643	Histidine kinase
MTX16_RS22605	COG2198	Histidine kinase
MTX16_RS22610	COG1776	CheC inhibitor of MCP methylation
MTX16_RS22610	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MTX16_RS22625	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MTX16_RS22645	COG1256	bacterial-type flagellum assembly
MTX16_RS22650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MTX16_RS22655	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MTX16_RS22670	COG1815	bacterial-type flagellum-dependent cell motility
MTX16_RS22675	COG1558	bacterial-type flagellum-dependent cell motility
MTX16_RS22685	COG1766	The M ring may be actively involved in energy transduction
MTX16_RS22690	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MTX16_RS22700	COG1157	protein secretion by the type III secretion system
MTX16_RS22735	COG0784	Response regulator, receiver
MTX16_RS22735	COG0835	chemotaxis
MTX16_RS22750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MTX16_RS22755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MTX16_RS22760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MTX16_RS22765	COG0741	lytic transglycosylase activity
MTX16_RS22775	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MTX16_RS22780	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MTX16_RS22780	COG1776	CheC inhibitor of MCP methylation
MTX16_RS22790	COG1338	Plays a role in the flagellum-specific transport system
MTX16_RS22795	COG1987	bacterial-type flagellum assembly
MTX16_RS22805	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MTX16_RS22810	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MTX16_RS22815	COG1419	protein localization to endoplasmic reticulum
MTX16_RS22820	COG4786	Flagellar basal body rod
MTX16_RS22825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MTX16_RS22860	COG2329	Antibiotic biosynthesis monooxygenase
MTX16_RS22885	COG0583	DNA-binding transcription factor activity
MTX16_RS22935	COG0406	alpha-ribazole phosphatase activity
MTX16_RS22965	COG0367	asparagine synthase
MTX16_RS22995	COG1802	Transcriptional regulator
MTX16_RS23000	COG0697	spore germination
MTX16_RS23010	COG0523	cobalamin synthesis protein
MTX16_RS23015	COG0701	Predicted permease
MTX16_RS23030	COG1757	Na H antiporter
MTX16_RS23035	COG0789	Transcriptional regulator
MTX16_RS23060	COG0534	Mate efflux family protein
MTX16_RS23065	COG3340	Belongs to the peptidase S51 family
MTX16_RS23085	COG0785	Cytochrome C biogenesis protein
MTX16_RS23105	COG0457	Tetratricopeptide repeat
MTX16_RS23125	COG2733	membrane
MTX16_RS23160	COG1131	(ABC) transporter
MTX16_RS23175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MTX16_RS23180	COG0528	UMP kinase activity
MTX16_RS23195	COG1027	Aspartate ammonia-lyase
MTX16_RS23200	COG0281	malic enzyme
MTX16_RS23205	COG4191	Histidine kinase
MTX16_RS23210	COG0784	Response regulator, receiver
MTX16_RS23215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MTX16_RS23260	COG2814	Major facilitator Superfamily
MTX16_RS23275	COG1695	Transcriptional regulator
MTX16_RS23290	COG0477	Major facilitator Superfamily
MTX16_RS23300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MTX16_RS23305	COG2223	nitrite transmembrane transporter activity
MTX16_RS23310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MTX16_RS23330	COG0733	neurotransmitter:sodium symporter activity
MTX16_RS23340	COG5566	PFAM Mor transcription activator
MTX16_RS23345	COG2323	membrane
MTX16_RS23365	COG2084	Dehydrogenase
MTX16_RS23380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MTX16_RS23390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MTX16_RS23395	COG0028	Belongs to the TPP enzyme family
MTX16_RS23415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MTX16_RS23440	COG2814	Major facilitator Superfamily
MTX16_RS23445	COG3384	dioxygenase
MTX16_RS23455	COG3279	Response regulator of the LytR AlgR family
MTX16_RS23460	COG0427	acetyl-CoA hydrolase
MTX16_RS23480	COG2814	Major facilitator Superfamily
MTX16_RS23485	COG1309	transcriptional regulator
MTX16_RS23490	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS23505	COG0457	Tetratricopeptide repeat
MTX16_RS23520	COG4166	transmembrane transport
MTX16_RS23525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS23545	COG1914	H( )-stimulated, divalent metal cation uptake system
MTX16_RS23560	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MTX16_RS23565	COG0531	amino acid
MTX16_RS23595	COG2309	aminopeptidase activity
MTX16_RS23610	COG0456	acetyltransferase
MTX16_RS23625	COG1309	transcriptional regulator
MTX16_RS23630	COG2390	Transcriptional regulator
MTX16_RS23640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MTX16_RS23645	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MTX16_RS23660	COG4846	Membrane protein involved in cytochrome C biogenesis
MTX16_RS23670	COG0006	proline dipeptidase activity
MTX16_RS23680	COG2132	Multicopper oxidase
MTX16_RS23690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MTX16_RS23710	COG1114	Component of the transport system for branched-chain amino acids
MTX16_RS23720	COG1910	domain protein
MTX16_RS23740	COG2318	DinB family
MTX16_RS23745	COG4122	O-methyltransferase activity
MTX16_RS23750	COG1280	lysine exporter protein (LysE YggA)
MTX16_RS23755	COG3403	YqcI/YcgG family
MTX16_RS23770	COG0725	ABC transporter, periplasmic molybdate-binding protein
MTX16_RS23775	COG0561	phosphatase activity
MTX16_RS23780	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MTX16_RS23790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MTX16_RS23795	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS23815	COG2372	response to copper ion
MTX16_RS23815	COG1276	copper resistance
MTX16_RS23820	COG4549	nuclear export factor GLE1
MTX16_RS23825	COG0697	spore germination
MTX16_RS23830	COG0583	DNA-binding transcription factor activity
MTX16_RS23835	COG1959	2 iron, 2 sulfur cluster binding
MTX16_RS23840	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MTX16_RS23845	COG0778	Nitroreductase
MTX16_RS23855	COG0628	permease
MTX16_RS23865	COG1231	oxidoreductase activity
MTX16_RS23870	COG0523	cobalamin synthesis protein
MTX16_RS23880	COG0411	ABC transporter
MTX16_RS23900	COG0583	DNA-binding transcription factor activity
MTX16_RS23935	COG1271	oxidase subunit
MTX16_RS23940	COG1294	oxidase, subunit
MTX16_RS23945	COG4988	ABC transporter
MTX16_RS23950	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MTX16_RS23960	COG1216	Glycosyl transferase, family 2
MTX16_RS24000	COG1686	Belongs to the peptidase S11 family
MTX16_RS24015	COG1388	LysM domain
MTX16_RS24015	COG0791	NLP P60 protein
MTX16_RS24025	COG1132	(ABC) transporter
MTX16_RS24030	COG0745	RESPONSE REGULATOR receiver
MTX16_RS24035	COG5002	protein histidine kinase activity
MTX16_RS24045	COG0300	oxidoreductase activity
MTX16_RS24075	COG0460	homoserine dehydrogenase
MTX16_RS24100	COG1316	TRANSCRIPTIONal
MTX16_RS24110	COG0745	RESPONSE REGULATOR receiver
MTX16_RS24115	COG5002	protein histidine kinase activity
MTX16_RS24130	COG1285	pathogenesis
MTX16_RS24135	COG1247	-acetyltransferase
MTX16_RS24155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MTX16_RS24165	COG1082	Xylose isomerase domain protein TIM barrel
MTX16_RS24175	COG2814	Major facilitator Superfamily
MTX16_RS24180	COG1279	arginine transmembrane transporter activity
MTX16_RS24185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTX16_RS24195	COG1752	Esterase of the alpha-beta hydrolase superfamily
MTX16_RS24230	COG0577	efflux transmembrane transporter activity
MTX16_RS24235	COG2002	toxin-antitoxin pair type II binding
MTX16_RS24240	COG1404	Belongs to the peptidase S8 family
MTX16_RS24245	COG0640	Transcriptional regulator
MTX16_RS24250	COG0667	Aldo Keto reductase
MTX16_RS24255	COG2814	Major facilitator Superfamily
MTX16_RS24260	COG3152	Membrane
MTX16_RS24285	COG0840	transmembrane signaling receptor activity
MTX16_RS24300	COG3949	Membrane
MTX16_RS24305	COG0783	Belongs to the Dps family
MTX16_RS24320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTX16_RS24330	COG1231	oxidoreductase activity
MTX16_RS24335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS24340	COG4989	oxidoreductase activity
MTX16_RS24345	COG0523	cobalamin synthesis protein
MTX16_RS24350	COG0456	acetyltransferase
MTX16_RS24355	COG0803	Belongs to the bacterial solute-binding protein 9 family
MTX16_RS24365	COG0702	epimerase
MTX16_RS24375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MTX16_RS24385	COG4166	transmembrane transport
MTX16_RS24410	COG5337	Spore coat protein CotH
MTX16_RS24415	COG1051	belongs to the nudix hydrolase family
MTX16_RS24420	COG0586	Pfam SNARE associated Golgi protein
MTX16_RS24425	COG2244	polysaccharide biosynthetic process
MTX16_RS24435	COG0701	Predicted permease
MTX16_RS24440	COG3689	TIGRFAM TIGR03943 family protein
MTX16_RS24445	COG1607	acyl-coa hydrolase
MTX16_RS24455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MTX16_RS24470	COG0702	epimerase
MTX16_RS24475	COG2839	Protein conserved in bacteria
MTX16_RS24480	COG1253	flavin adenine dinucleotide binding
MTX16_RS24495	COG1114	Component of the transport system for branched-chain amino acids
MTX16_RS24500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MTX16_RS24520	COG0860	N-Acetylmuramoyl-L-alanine amidase
MTX16_RS24530	COG1876	peptidase activity
MTX16_RS24540	COG0154	amidase activity
MTX16_RS24545	COG2211	Major facilitator Superfamily
MTX16_RS24560	COG0860	N-Acetylmuramoyl-L-alanine amidase
MTX16_RS24570	COG0561	phosphatase activity
MTX16_RS24585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MTX16_RS24605	COG1819	glycosyl
MTX16_RS24610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTX16_RS24615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTX16_RS24645	COG0456	acetyltransferase
MTX16_RS24680	COG4499	WXG100 protein secretion system (Wss), protein YukC
MTX16_RS24735	COG3874	Sporulation protein YtfJ
MTX16_RS24760	COG2226	methyltransferase
MTX16_RS24780	COG1082	Xylose isomerase domain protein TIM barrel
MTX16_RS24785	COG0346	lactoylglutathione lyase activity
MTX16_RS24795	COG0604	alcohol dehydrogenase
MTX16_RS24800	COG1595	DNA-templated transcription, initiation
MTX16_RS24815	COG0426	domain, Protein
MTX16_RS24815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MTX16_RS24825	COG0386	Belongs to the glutathione peroxidase family
MTX16_RS24830	COG1305	Transglutaminase-like
MTX16_RS24835	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
MTX16_RS24840	COG0714	Associated with various cellular activities
MTX16_RS24845	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MTX16_RS24850	COG1140	nitrate reductase beta subunit
MTX16_RS24855	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MTX16_RS24860	COG2181	nitrate reductase activity
MTX16_RS24865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MTX16_RS24870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MTX16_RS24875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MTX16_RS24880	COG0303	'Molybdopterin
MTX16_RS24885	COG0314	molybdopterin synthase activity
MTX16_RS24895	COG2223	nitrite transmembrane transporter activity
MTX16_RS24915	COG1648	precorrin-2 dehydrogenase activity
MTX16_RS24925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MTX16_RS24925	COG1587	Uroporphyrinogen-III synthase
MTX16_RS24930	COG2146	nitrite reductase [NAD(P)H] activity
MTX16_RS24935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MTX16_RS24940	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MTX16_RS24975	COG2359	stage V sporulation protein S
MTX16_RS25000	COG0457	Tetratricopeptide repeat
MTX16_RS25015	COG1418	mRNA catabolic process
MTX16_RS25020	COG0488	(ABC) transporter
MTX16_RS25035	COG0629	single-stranded DNA binding
MTX16_RS25040	COG1413	lyase activity
MTX16_RS25055	COG2136	Putative SAM-dependent methyltransferase
MTX16_RS25055	COG2521	methyltransferase
MTX16_RS25060	COG0018	arginyl-trna synthetase
MTX16_RS25100	COG0017	Asparaginyl-tRNA synthetase
MTX16_RS25105	COG1929	Belongs to the glycerate kinase type-1 family
MTX16_RS25115	COG0745	RESPONSE REGULATOR receiver
MTX16_RS25120	COG3850	Histidine kinase
MTX16_RS25120	COG5002	protein histidine kinase activity
MTX16_RS25135	COG0733	neurotransmitter:sodium symporter activity
MTX16_RS25160	COG2610	gluconate transmembrane transporter activity
MTX16_RS25170	COG1794	racemase activity, acting on amino acids and derivatives
MTX16_RS25180	COG0456	acetyltransferase
MTX16_RS25190	COG3655	Transcriptional regulator
MTX16_RS25195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MTX16_RS25205	COG1131	(ABC) transporter
MTX16_RS25210	COG4473	ABC transporter
MTX16_RS25235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MTX16_RS25250	COG0768	penicillin binding
MTX16_RS25260	COG0204	Acyl-transferase
MTX16_RS25265	COG1272	protein, Hemolysin III
MTX16_RS25275	COG0805	protein transport
MTX16_RS25285	COG1307	EDD domain protein, DegV family
MTX16_RS25295	COG1999	signal sequence binding
MTX16_RS25300	COG0071	Belongs to the small heat shock protein (HSP20) family
MTX16_RS25305	COG0367	asparagine synthase
MTX16_RS25320	COG0860	N-Acetylmuramoyl-L-alanine amidase
MTX16_RS25325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTX16_RS25330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MTX16_RS25345	COG1335	isochorismatase
MTX16_RS25360	COG0668	transmembrane transport
MTX16_RS25365	COG4585	Histidine kinase
MTX16_RS25365	COG2203	Gaf domain
MTX16_RS25370	COG2197	response regulator
MTX16_RS25375	COG1737	Transcriptional regulator
MTX16_RS25380	COG0384	phenazine biosynthesis protein PhzF
MTX16_RS25385	COG1064	alcohol dehydrogenase
MTX16_RS25410	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MTX16_RS25445	COG1125	glycine betaine transport
MTX16_RS25445	COG0517	IMP dehydrogenase activity
MTX16_RS25450	COG1174	glycine betaine transport
MTX16_RS25485	COG1253	flavin adenine dinucleotide binding
MTX16_RS25490	COG1012	belongs to the aldehyde dehydrogenase family
MTX16_RS25495	COG5506	Protein of unknown function (DUF1694)
MTX16_RS25510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MTX16_RS25515	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MTX16_RS25520	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MTX16_RS25525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MTX16_RS25530	COG0456	acetyltransferase
MTX16_RS25535	COG3829	transcription factor binding
MTX16_RS25540	COG1509	lysine 2,3-aminomutase activity
MTX16_RS25575	COG0515	serine threonine protein kinase
MTX16_RS25575	COG4991	sh3 domain protein
MTX16_RS25575	COG3064	Membrane
MTX16_RS25585	COG0671	phosphoesterase, PA-phosphatase related
MTX16_RS25590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MTX16_RS25595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MTX16_RS25690	COG0300	oxidoreductase activity
MTX16_RS25710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MTX16_RS25710	COG4499	WXG100 protein secretion system (Wss), protein YukC
MTX16_RS25720	COG2814	Major facilitator Superfamily
MTX16_RS25725	COG4841	protein insertion into membrane
MTX16_RS25730	COG0372	Belongs to the citrate synthase family
MTX16_RS25735	COG2079	MmgE PrpD family protein
MTX16_RS25740	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MTX16_RS25745	COG1960	acyl-CoA dehydrogenase activity
MTX16_RS25750	COG2084	Dehydrogenase
MTX16_RS25760	COG1280	lysine exporter protein (LysE YggA)
MTX16_RS25765	COG1024	Enoyl-CoA hydratase
MTX16_RS25780	COG0420	3'-5' exonuclease activity
MTX16_RS25785	COG0419	ATPase involved in DNA repair
MTX16_RS25810	COG2223	nitrite transmembrane transporter activity
MTX16_RS25815	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS25820	COG1169	isochorismate synthase
MTX16_RS25825	COG1021	2,3-dihydroxybenzoate-AMP ligase
MTX16_RS25830	COG1535	isochorismatase
MTX16_RS25830	COG3433	isochorismatase activity
MTX16_RS25835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MTX16_RS25840	COG3251	PFAM MbtH domain protein
MTX16_RS25845	COG2814	Major facilitator Superfamily
MTX16_RS25860	COG0776	regulation of translation
MTX16_RS25870	COG2318	DinB family
MTX16_RS25880	COG1115	amino acid carrier protein
MTX16_RS25900	COG1187	pseudouridine synthase activity
MTX16_RS25905	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MTX16_RS25910	COG1136	(ABC) transporter
MTX16_RS25955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MTX16_RS25970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTX16_RS26015	COG1247	-acetyltransferase
MTX16_RS26040	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MTX16_RS26050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS26080	COG0583	DNA-binding transcription factor activity
MTX16_RS26085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MTX16_RS26100	COG0583	DNA-binding transcription factor activity
MTX16_RS26105	COG2258	MOSC domain
MTX16_RS26120	COG1132	(ABC) transporter
MTX16_RS26125	COG1132	(ABC) transporter
MTX16_RS26150	COG1396	sequence-specific DNA binding
MTX16_RS26180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MTX16_RS26185	COG1595	DNA-templated transcription, initiation
MTX16_RS26215	COG1649	PFAM Uncharacterised BCR, COG1649
MTX16_RS26240	COG2971	BadF BadG BcrA BcrD
MTX16_RS26250	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MTX16_RS26260	COG1846	Transcriptional regulator
MTX16_RS26275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MTX16_RS26295	COG1309	transcriptional regulator
MTX16_RS26380	COG3615	Tellurite resistance protein tehB
MTX16_RS26380	COG0500	methyltransferase
MTX16_RS26400	COG1846	Transcriptional regulator
MTX16_RS26430	COG2195	Cleaves the N-terminal amino acid of tripeptides
MTX16_RS26455	COG2002	toxin-antitoxin pair type II binding
MTX16_RS26465	COG0730	response to heat
MTX16_RS26470	COG0110	maltose O-acetyltransferase activity
MTX16_RS26475	COG1686	Belongs to the peptidase S11 family
MTX16_RS26490	COG2814	Major facilitator Superfamily
MTX16_RS26525	COG2312	Erythromycin esterase
MTX16_RS26530	COG0741	lytic transglycosylase activity
MTX16_RS26535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS26575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MTX16_RS26580	COG0768	penicillin binding
MTX16_RS26585	COG1595	DNA-templated transcription, initiation
MTX16_RS26595	COG0768	penicillin binding
MTX16_RS26600	COG0768	penicillin binding
MTX16_RS26610	COG1408	metallophosphoesterase
MTX16_RS26620	COG1131	(ABC) transporter
MTX16_RS26630	COG1309	transcriptional regulator
MTX16_RS26645	COG1960	acyl-CoA dehydrogenase activity
MTX16_RS26650	COG0439	Biotin carboxylase
MTX16_RS26655	COG0511	ligase activity, forming carbon-carbon bonds
MTX16_RS26660	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MTX16_RS26665	COG1024	Enoyl-CoA hydratase
MTX16_RS26670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MTX16_RS26675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MTX16_RS26695	COG0572	uridine kinase
MTX16_RS26715	COG1686	Belongs to the peptidase S11 family
MTX16_RS26740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MTX16_RS26760	COG3227	Zinc metalloprotease (Elastase)
MTX16_RS26765	COG2207	Transcriptional regulator
MTX16_RS26795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MTX16_RS26805	COG2814	Major facilitator Superfamily
MTX16_RS26810	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS26815	COG1733	regulation of RNA biosynthetic process
MTX16_RS26820	COG2226	methyltransferase
MTX16_RS26835	COG1942	4-Oxalocrotonate Tautomerase
MTX16_RS26840	COG0583	DNA-binding transcription factor activity
MTX16_RS26865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTX16_RS26900	COG3386	PFAM SMP-30 Gluconolaconase
MTX16_RS26910	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
MTX16_RS26915	COG3773	Cell wall hydrolase
MTX16_RS26925	COG0745	RESPONSE REGULATOR receiver
MTX16_RS26930	COG2205	protein histidine kinase activity
MTX16_RS26940	COG0488	(ABC) transporter
MTX16_RS26950	COG1136	(ABC) transporter
MTX16_RS26955	COG0577	efflux transmembrane transporter activity
MTX16_RS26975	COG0460	homoserine dehydrogenase
MTX16_RS26980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTX16_RS26990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MTX16_RS27015	COG0582	viral genome integration into host DNA
MTX16_RS27035	COG1396	sequence-specific DNA binding
MTX16_RS27060	COG2002	toxin-antitoxin pair type II binding
MTX16_RS27140	COG0582	viral genome integration into host DNA
MTX16_RS27155	COG5634	Uncharacterized conserved protein (DUF2278)
MTX16_RS27180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MTX16_RS27190	COG0741	lytic transglycosylase activity
MTX16_RS27205	COG2755	lipolytic protein G-D-S-L family
MTX16_RS27205	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MTX16_RS27240	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MTX16_RS27265	COG0596	Alpha beta hydrolase
MTX16_RS27350	COG2002	toxin-antitoxin pair type II binding
MTX16_RS27370	COG0582	viral genome integration into host DNA
MTX16_RS27415	COG1819	glycosyl
MTX16_RS27420	COG0596	Alpha beta hydrolase
MTX16_RS27425	COG0596	Alpha beta hydrolase
MTX16_RS27440	COG2801	Transposase and inactivated derivatives
MTX16_RS27480	COG4990	cell redox homeostasis
MTX16_RS27495	COG3647	Membrane
MTX16_RS27500	COG0671	phosphoesterase, PA-phosphatase related
MTX16_RS27515	COG2323	membrane
MTX16_RS27555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MTX16_RS27560	COG0438	transferase activity, transferring glycosyl groups
MTX16_RS27565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MTX16_RS27580	COG0438	transferase activity, transferring glycosyl groups
MTX16_RS27585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MTX16_RS27590	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MTX16_RS27595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MTX16_RS27750	COG0457	Tetratricopeptide repeat
MTX16_RS27750	COG0463	Glycosyl transferase, family 2
MTX16_RS27755	COG2816	NAD+ diphosphatase activity
MTX16_RS27785	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS27805	COG1136	(ABC) transporter
MTX16_RS27810	COG0577	efflux transmembrane transporter activity
MTX16_RS27875	COG0531	amino acid
MTX16_RS27880	COG1522	sequence-specific DNA binding
MTX16_RS27885	COG1760	l-serine dehydratase
MTX16_RS27890	COG1760	l-serine dehydratase
MTX16_RS27895	COG0814	amino acid
MTX16_RS27910	COG1309	transcriptional regulator
MTX16_RS27915	COG2814	Major facilitator Superfamily
MTX16_RS27920	COG2184	nucleotidyltransferase activity
MTX16_RS27930	COG0456	acetyltransferase
MTX16_RS27945	COG3486	L-lysine 6-monooxygenase (NADPH) activity
MTX16_RS27950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MTX16_RS27960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MTX16_RS27975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MTX16_RS27975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MTX16_RS27980	COG0527	aspartate kinase activity
MTX16_RS27995	COG0745	RESPONSE REGULATOR receiver
MTX16_RS28000	COG2169	Transcriptional regulator
MTX16_RS28030	COG2356	endonuclease I
MTX16_RS28040	COG1404	Belongs to the peptidase S8 family
MTX16_RS28050	COG1404	Belongs to the peptidase S8 family
MTX16_RS28080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MTX16_RS28080	COG5549	protein import
MTX16_RS28100	COG4974	Belongs to the 'phage' integrase family
MTX16_RS28150	COG0463	Glycosyl transferase, family 2
MTX16_RS28215	COG1183	phosphatidylcholine synthase activity
MTX16_RS28295	COG1252	NADH dehydrogenase
MTX16_RS28310	COG0584	glycerophosphoryl diester phosphodiesterase
MTX16_RS28345	COG0823	Involved in the tonB-independent uptake of proteins
MTX16_RS28350	COG3397	chitin binding
MTX16_RS28370	COG0697	spore germination
MTX16_RS28385	COG0457	Tetratricopeptide repeat
MTX16_RS28460	COG1388	LysM domain
MTX16_RS28460	COG3942	CHAP domain
MTX16_RS28465	COG1388	LysM domain
MTX16_RS28465	COG0791	NLP P60 protein
MTX16_RS28495	COG3718	enzyme involved in inositol metabolism
MTX16_RS28525	COG0673	inositol 2-dehydrogenase activity
MTX16_RS28530	COG2814	Major facilitator Superfamily
MTX16_RS28535	COG1609	Transcriptional regulator
MTX16_RS28590	COG0667	Aldo Keto reductase
MTX16_RS28620	COG4641	Protein conserved in bacteria
MTX16_RS28625	COG2089	acid synthase
MTX16_RS28640	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MTX16_RS28645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MTX16_RS28650	COG1088	dTDP-glucose 4,6-dehydratase activity
MTX16_RS28655	COG1086	Polysaccharide biosynthesis protein
MTX16_RS28665	COG0463	Glycosyl transferase, family 2
MTX16_RS28670	COG0463	Glycosyl transferase, family 2
MTX16_RS28675	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS28685	COG2089	acid synthase
MTX16_RS28690	COG1028	Short-chain dehydrogenase reductase Sdr
MTX16_RS28700	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MTX16_RS28705	COG3391	amine dehydrogenase activity
MTX16_RS28720	COG1396	sequence-specific DNA binding
MTX16_RS28750	COG1216	Glycosyl transferase, family 2
MTX16_RS28755	COG1024	Enoyl-CoA hydratase
MTX16_RS28770	COG3800	Transcriptional regulator
MTX16_RS28770	COG1396	sequence-specific DNA binding
MTX16_RS28780	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MTX16_RS28810	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
MTX16_RS28895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MTX16_RS28900	COG5632	N-Acetylmuramoyl-L-alanine amidase
MTX16_RS28900	COG3409	Peptidoglycan-binding domain 1 protein
MTX16_RS28925	COG1396	sequence-specific DNA binding
MTX16_RS29070	COG1404	Belongs to the peptidase S8 family
MTX16_RS29105	COG3402	PFAM membrane-flanked domain
MTX16_RS29120	COG1136	(ABC) transporter
MTX16_RS29125	COG0577	efflux transmembrane transporter activity
MTX16_RS29135	COG1725	Transcriptional regulator
MTX16_RS29165	COG2732	(Barnase) inhibitor
MTX16_RS29215	COG1192	Involved in chromosome partitioning
MTX16_RS29275	COG2274	protein secretion by the type I secretion system
MTX16_RS29275	COG3271	cysteine-type peptidase activity
MTX16_RS29280	COG3118	belongs to the thioredoxin family
MTX16_RS29285	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MTX16_RS29295	COG2197	response regulator
MTX16_RS29315	COG5002	protein histidine kinase activity
MTX16_RS29320	COG0745	RESPONSE REGULATOR receiver
MTX16_RS29355	COG0450	alkyl hydroperoxide reductase
MTX16_RS29360	COG0833	amino acid
MTX16_RS29370	COG1982	Orn Lys Arg decarboxylase major
MTX16_RS29375	COG2249	NAD(P)H dehydrogenase (quinone) activity
MTX16_RS29380	COG1733	regulation of RNA biosynthetic process
MTX16_RS29385	COG0110	maltose O-acetyltransferase activity
MTX16_RS29390	COG1733	regulation of RNA biosynthetic process
MTX16_RS29425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MTX16_RS29475	COG0457	Tetratricopeptide repeat
MTX16_RS29570	COG0739	heme binding
MTX16_RS29605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MTX16_RS29680	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MTX16_RS29695	COG1395	domain, Protein
MTX16_RS29750	COG1192	Involved in chromosome partitioning
MTX16_RS29770	COG2312	Erythromycin esterase
MTX16_RS29865	COG0582	viral genome integration into host DNA
MTX16_RS29875	COG3209	COG3209 Rhs family protein
MTX16_RS29890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MTX16_RS29950	COG1923	regulation of RNA biosynthetic process
MTX16_RS30015	COG0484	heat shock protein binding
MTX16_RS30120	COG0582	viral genome integration into host DNA
MTX16_RS30130	COG1131	(ABC) transporter
MTX16_RS30155	COG1136	(ABC) transporter
MTX16_RS30160	COG0577	efflux transmembrane transporter activity
MTX16_RS30220	COG3620	sequence-specific DNA binding