locus-tag	class	description
BT246_RS00010	COG0592	DNA-directed DNA polymerase activity
BT246_RS00015	COG2501	S4 domain
BT246_RS00025	COG0187	DNA topoisomerase II activity
BT246_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BT246_RS00065	COG0517	IMP dehydrogenase activity
BT246_RS00065	COG0516	GMP reductase activity
BT246_RS00070	COG1686	Belongs to the peptidase S11 family
BT246_RS00100	COG1428	Deoxynucleoside kinase
BT246_RS00105	COG1428	Deoxynucleoside kinase
BT246_RS00110	COG1335	isochorismatase
BT246_RS00115	COG0590	tRNA wobble adenosine to inosine editing
BT246_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BT246_RS00180	COG1982	Orn Lys Arg decarboxylase major
BT246_RS00190	COG0470	DNA polymerase III
BT246_RS00195	COG1774	PSP1 C-terminal conserved region
BT246_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BT246_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BT246_RS00220	COG2002	toxin-antitoxin pair type II binding
BT246_RS00230	COG0084	hydrolase, TatD family'
BT246_RS00250	COG4466	Protein conserved in bacteria
BT246_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BT246_RS00270	COG0251	oxidation-reduction process
BT246_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BT246_RS00305	COG2002	toxin-antitoxin pair type II binding
BT246_RS00310	COG2244	polysaccharide biosynthetic process
BT246_RS00315	COG3956	TIGRFAM MazG family protein
BT246_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BT246_RS00340	COG1098	S1 RNA binding domain
BT246_RS00355	COG2208	phosphoserine phosphatase activity
BT246_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BT246_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BT246_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BT246_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BT246_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
BT246_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BT246_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BT246_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BT246_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BT246_RS00420	COG1396	sequence-specific DNA binding
BT246_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BT246_RS00515	COG3880	PFAM UvrB UvrC protein
BT246_RS00525	COG0542	response to heat
BT246_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BT246_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
BT246_RS00560	COG1045	serine acetyltransferase
BT246_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BT246_RS00580	COG3688	RNA-binding protein containing a PIN domain
BT246_RS00590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BT246_RS00595	COG0250	Participates in transcription elongation, termination and antitermination
BT246_RS00600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BT246_RS00615	COG0222	ribosome binding
BT246_RS00620	COG2813	Specifically methylates the guanine in position
BT246_RS00630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BT246_RS00635	COG1358	cellular component organization or biogenesis
BT246_RS00640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BT246_RS00660	COG0051	transcription antitermination factor activity, RNA binding
BT246_RS00665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BT246_RS00705	COG0255	Belongs to the universal ribosomal protein uL29 family
BT246_RS00765	COG0201	protein transport
BT246_RS00775	COG0024	Methionine aminopeptidase
BT246_RS00785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BT246_RS00820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BT246_RS00845	COG0860	N-Acetylmuramoyl-L-alanine amidase
BT246_RS00850	COG0489	protein tyrosine kinase activity
BT246_RS00860	COG2194	sulfuric ester hydrolase activity
BT246_RS00865	COG0726	polysaccharide deacetylase
BT246_RS00945	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BT246_RS00950	COG4856	YbbR-like protein
BT246_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS00995	COG2011	ABC-type metal ion transport system permease component
BT246_RS01000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BT246_RS01005	COG1464	Belongs to the NlpA lipoprotein family
BT246_RS01010	COG0604	alcohol dehydrogenase
BT246_RS01035	COG2271	Major facilitator Superfamily
BT246_RS01045	COG2814	Major facilitator Superfamily
BT246_RS01065	COG0601	transmembrane transport
BT246_RS01075	COG0444	Belongs to the ABC transporter superfamily
BT246_RS01080	COG4608	Belongs to the ABC transporter superfamily
BT246_RS01085	COG4166	transmembrane transport
BT246_RS01105	COG4166	transmembrane transport
BT246_RS01110	COG4166	transmembrane transport
BT246_RS01115	COG0656	L-ascorbic acid biosynthetic process
BT246_RS01135	COG4149	molybdate abc transporter
BT246_RS01140	COG0725	ABC transporter, periplasmic molybdate-binding protein
BT246_RS01145	COG1910	domain protein
BT246_RS01160	COG0697	spore germination
BT246_RS01180	COG0204	Acyl-transferase
BT246_RS01190	COG1609	Transcriptional regulator
BT246_RS01200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT246_RS01220	COG5298	Protein conserved in bacteria
BT246_RS01245	COG0488	(ABC) transporter
BT246_RS01255	COG0747	negative chemotaxis
BT246_RS01260	COG0601	transmembrane transport
BT246_RS01265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BT246_RS01270	COG0444	Belongs to the ABC transporter superfamily
BT246_RS01275	COG4608	Belongs to the ABC transporter superfamily
BT246_RS01280	COG0561	phosphatase activity
BT246_RS01310	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BT246_RS01315	COG0179	Fumarylacetoacetate (FAA) hydrolase
BT246_RS01325	COG0531	amino acid
BT246_RS01330	COG2814	Major facilitator Superfamily
BT246_RS01340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BT246_RS01350	COG4294	response to UV
BT246_RS01355	COG0705	Rhomboid family
BT246_RS01365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BT246_RS01370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BT246_RS01375	COG0864	Transcriptional regulator
BT246_RS01380	COG2337	Toxic component of a toxin-antitoxin (TA) module
BT246_RS01385	COG2183	response to ionizing radiation
BT246_RS01480	COG0802	atpase or kinase
BT246_RS01485	COG1214	PFAM Peptidase M22, glycoprotease
BT246_RS01490	COG0456	acetyltransferase
BT246_RS01500	COG0488	(ABC) transporter
BT246_RS01515	COG1266	CAAX protease self-immunity
BT246_RS01535	COG2252	PERMEase
BT246_RS01545	COG5002	protein histidine kinase activity
BT246_RS01570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BT246_RS01590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT246_RS01595	COG0506	proline dehydrogenase activity
BT246_RS01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BT246_RS01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BT246_RS01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BT246_RS01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BT246_RS01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BT246_RS01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BT246_RS01670	COG0151	Belongs to the GarS family
BT246_RS01690	COG0583	DNA-binding transcription factor activity
BT246_RS01715	COG0210	DNA helicase
BT246_RS01725	COG4851	CamS sex pheromone cAM373 precursor
BT246_RS01740	COG1335	isochorismatase
BT246_RS01750	COG2011	ABC-type metal ion transport system permease component
BT246_RS01755	COG1464	Belongs to the NlpA lipoprotein family
BT246_RS01765	COG0003	Pfam Anion-transporting ATPase
BT246_RS01770	COG1846	Transcriptional regulator
BT246_RS01775	COG4682	membrane
BT246_RS01795	COG1597	lipid kinase activity
BT246_RS01800	COG0546	phosphoglycolate phosphatase activity
BT246_RS01805	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BT246_RS01815	COG1012	belongs to the aldehyde dehydrogenase family
BT246_RS01820	COG2076	Multidrug Resistance protein
BT246_RS01830	COG2309	aminopeptidase activity
BT246_RS01840	COG0582	viral genome integration into host DNA
BT246_RS01860	COG1396	sequence-specific DNA binding
BT246_RS01895	COG5377	YqaJ viral recombinase family
BT246_RS01905	COG3723	Recombinational DNA repair protein, rece pathway
BT246_RS01915	COG0305	Participates in initiation and elongation during chromosome replication
BT246_RS01945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BT246_RS01970	COG3617	BRO family, N-terminal domain
BT246_RS02015	COG5484	DNA packaging
BT246_RS02100	COG5632	N-Acetylmuramoyl-L-alanine amidase
BT246_RS02130	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS02145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT246_RS02155	COG0582	viral genome integration into host DNA
BT246_RS02205	COG1846	Transcriptional regulator
BT246_RS02215	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BT246_RS02225	COG2002	toxin-antitoxin pair type II binding
BT246_RS02270	COG0582	viral genome integration into host DNA
BT246_RS02275	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS02280	COG0582	viral genome integration into host DNA
BT246_RS02405	COG5632	N-Acetylmuramoyl-L-alanine amidase
BT246_RS02425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BT246_RS02440	COG4807	Protein conserved in bacteria
BT246_RS02465	COG1757	Na H antiporter
BT246_RS02470	COG1473	amidohydrolase
BT246_RS02485	COG0450	alkyl hydroperoxide reductase
BT246_RS02505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT246_RS02510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT246_RS02515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT246_RS02520	COG0492	ferredoxin-NADP+ reductase activity
BT246_RS02530	COG0166	Belongs to the GPI family
BT246_RS02555	COG5002	protein histidine kinase activity
BT246_RS02575	COG3541	Predicted nucleotidyltransferase
BT246_RS02580	COG2814	Major facilitator Superfamily
BT246_RS02585	COG0723	plastoquinol--plastocyanin reductase activity
BT246_RS02585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BT246_RS02595	COG0765	amino acid transport
BT246_RS02600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BT246_RS02615	COG0840	transmembrane signaling receptor activity
BT246_RS02640	COG0549	Belongs to the carbamate kinase family
BT246_RS02645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BT246_RS02655	COG0277	FAD linked oxidase domain protein
BT246_RS02660	COG0366	Alpha amylase catalytic
BT246_RS02665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BT246_RS02665	COG2190	(PTS) system
BT246_RS02665	COG1263	PTS System
BT246_RS02695	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BT246_RS02720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BT246_RS02735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BT246_RS02745	COG1116	anion transmembrane transporter activity
BT246_RS02750	COG0488	(ABC) transporter
BT246_RS02795	COG2270	Major facilitator Superfamily
BT246_RS02825	COG2310	stress, protein
BT246_RS02830	COG2310	stress, protein
BT246_RS02835	COG2310	stress, protein
BT246_RS02840	COG0861	Integral membrane protein TerC family
BT246_RS02850	COG3853	Toxic anion resistance protein (TelA)
BT246_RS02865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BT246_RS02875	COG1295	ribonuclease BN
BT246_RS02880	COG2217	Heavy metal translocating P-type atpase
BT246_RS02885	COG0697	spore germination
BT246_RS02895	COG0681	Belongs to the peptidase S26 family
BT246_RS02905	COG0586	Pfam SNARE associated Golgi protein
BT246_RS02920	COG3871	stress protein (general stress protein 26)
BT246_RS02925	COG0387	Pfam Sodium calcium exchanger
BT246_RS02935	COG0535	radical SAM domain protein
BT246_RS02955	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BT246_RS02960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BT246_RS02975	COG3829	transcription factor binding
BT246_RS02985	COG0833	amino acid
BT246_RS02990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BT246_RS03015	COG1263	PTS System
BT246_RS03015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BT246_RS03020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BT246_RS03035	COG1216	Glycosyl transferase, family 2
BT246_RS03045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BT246_RS03045	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BT246_RS03050	COG0463	Glycosyl transferase, family 2
BT246_RS03060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BT246_RS03080	COG1228	amidohydrolase
BT246_RS03085	COG1090	epimerase
BT246_RS03115	COG1988	membrane-bound metal-dependent
BT246_RS03120	COG1194	a g-specific adenine glycosylase
BT246_RS03140	COG3557	Belongs to the UPF0374 family
BT246_RS03145	COG1132	(ABC) transporter
BT246_RS03150	COG4129	membrane
BT246_RS03155	COG0067	glutamate synthase
BT246_RS03155	COG0070	glutamate synthase
BT246_RS03155	COG0069	glutamate synthase activity
BT246_RS03165	COG4555	ABC transporter
BT246_RS03185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BT246_RS03190	COG0735	belongs to the Fur family
BT246_RS03310	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BT246_RS03335	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BT246_RS03340	COG5001	Diguanylate cyclase
BT246_RS03340	COG1716	ATPase activity
BT246_RS03345	COG2766	serine protein kinase
BT246_RS03360	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS03365	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS03375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT246_RS03380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BT246_RS03390	COG0582	viral genome integration into host DNA
BT246_RS03445	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS03615	COG1585	Membrane protein implicated in regulation of membrane protease activity
BT246_RS03620	COG2268	Band 7 protein
BT246_RS03630	COG3290	protein histidine kinase activity
BT246_RS03635	COG4565	transcriptional regulatory protein
BT246_RS03640	COG2851	Citrate transporter
BT246_RS03675	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BT246_RS03680	COG3842	ATPase activity
BT246_RS03685	COG1175	transmembrane transport
BT246_RS03690	COG0395	ABC-type sugar transport system, permease component
BT246_RS03700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BT246_RS03705	COG0745	RESPONSE REGULATOR receiver
BT246_RS03710	COG5002	protein histidine kinase activity
BT246_RS03720	COG4990	cell redox homeostasis
BT246_RS03730	COG3290	protein histidine kinase activity
BT246_RS03735	COG4565	transcriptional regulatory protein
BT246_RS03740	COG3493	citrate carrier protein
BT246_RS03745	COG0281	malic enzyme
BT246_RS03755	COG0697	spore germination
BT246_RS03760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT246_RS03770	COG5002	protein histidine kinase activity
BT246_RS03775	COG0745	RESPONSE REGULATOR receiver
BT246_RS03785	COG0456	acetyltransferase
BT246_RS03785	COG0454	-acetyltransferase
BT246_RS03790	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BT246_RS03795	COG3383	formate dehydrogenase (NAD+) activity
BT246_RS03800	COG2427	Protein of unknown function (DUF1641)
BT246_RS03815	COG0531	amino acid
BT246_RS03820	COG0640	Transcriptional regulator
BT246_RS03825	COG2217	Heavy metal translocating P-type atpase
BT246_RS03830	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BT246_RS03860	COG2720	vancomycin resistance protein
BT246_RS03865	COG1316	TRANSCRIPTIONal
BT246_RS03870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT246_RS03875	COG0346	lactoylglutathione lyase activity
BT246_RS03880	COG1253	flavin adenine dinucleotide binding
BT246_RS03885	COG1027	Aspartate ammonia-lyase
BT246_RS03890	COG1620	l-lactate permease
BT246_RS03905	COG3104	oligopeptide transport
BT246_RS03910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT246_RS03915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT246_RS03920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT246_RS03935	COG0156	8-amino-7-oxononanoate synthase activity
BT246_RS03940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BT246_RS03950	COG4548	von Willebrand factor, type A
BT246_RS03955	COG0714	Associated with various cellular activities
BT246_RS03975	COG0531	amino acid
BT246_RS03980	COG2188	Transcriptional regulator
BT246_RS03985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BT246_RS03985	COG1263	PTS System
BT246_RS03990	COG0366	Alpha amylase catalytic
BT246_RS04005	COG0697	spore germination
BT246_RS04010	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BT246_RS04015	COG1115	amino acid carrier protein
BT246_RS04020	COG1126	abc transporter atp-binding protein
BT246_RS04025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BT246_RS04030	COG0765	amino acid transport
BT246_RS04035	COG0765	amino acid transport
BT246_RS04040	COG0833	amino acid
BT246_RS04055	COG1595	DNA-templated transcription, initiation
BT246_RS04065	COG2378	regulation of single-species biofilm formation
BT246_RS04070	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BT246_RS04075	COG5002	protein histidine kinase activity
BT246_RS04090	COG0659	secondary active sulfate transmembrane transporter activity
BT246_RS04115	COG0601	transmembrane transport
BT246_RS04125	COG4608	Belongs to the ABC transporter superfamily
BT246_RS04135	COG2271	Major facilitator Superfamily
BT246_RS04140	COG1846	Transcriptional regulator
BT246_RS04145	COG0477	Major facilitator Superfamily
BT246_RS04150	COG1609	Transcriptional regulator
BT246_RS04155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BT246_RS04170	COG1172	Belongs to the binding-protein-dependent transport system permease family
BT246_RS04175	COG1879	ABC-type sugar transport system periplasmic component
BT246_RS04200	COG1063	alcohol dehydrogenase
BT246_RS04250	COG0840	transmembrane signaling receptor activity
BT246_RS04255	COG3584	3D domain protein
BT246_RS04255	COG1388	LysM domain
BT246_RS04260	COG1476	TRANSCRIPTIONal
BT246_RS04295	COG3104	oligopeptide transport
BT246_RS04300	COG1114	Component of the transport system for branched-chain amino acids
BT246_RS04315	COG1113	amino acid transport
BT246_RS04320	COG2252	PERMEase
BT246_RS04335	COG2153	protein acetylation
BT246_RS04345	COG0569	domain protein
BT246_RS04345	COG0475	glutathione-regulated potassium exporter activity
BT246_RS04355	COG1845	cytochrome c oxidase, subunit III
BT246_RS04360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BT246_RS04370	COG0833	amino acid
BT246_RS04375	COG4990	cell redox homeostasis
BT246_RS04395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BT246_RS04400	COG0697	spore germination
BT246_RS04405	COG0531	amino acid
BT246_RS04415	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BT246_RS04420	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BT246_RS04425	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BT246_RS04425	COG1918	ferrous iron import across plasma membrane
BT246_RS04430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BT246_RS04435	COG0573	inorganic phosphate transmembrane transporter activity
BT246_RS04440	COG0581	inorganic phosphate transmembrane transporter activity
BT246_RS04450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BT246_RS04460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BT246_RS04580	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BT246_RS04600	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BT246_RS04605	COG1116	anion transmembrane transporter activity
BT246_RS04610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BT246_RS04615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BT246_RS04620	COG0352	thiamine-phosphate diphosphorylase activity
BT246_RS04625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BT246_RS04630	COG2104	thiamine diphosphate biosynthetic process
BT246_RS04640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BT246_RS04645	COG0351	phosphomethylpyrimidine kinase
BT246_RS04685	COG2205	protein histidine kinase activity
BT246_RS04690	COG2814	Major facilitator Superfamily
BT246_RS04695	COG1846	Transcriptional regulator
BT246_RS04710	COG2252	PERMEase
BT246_RS04715	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS04775	COG0778	Nitroreductase
BT246_RS04780	COG2719	SpoVR family
BT246_RS04790	COG1414	Transcriptional regulator
BT246_RS04805	COG0446	pyridine nucleotide-disulphide oxidoreductase
BT246_RS04810	COG1937	Protein conserved in bacteria
BT246_RS04815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BT246_RS04815	COG0425	Belongs to the sulfur carrier protein TusA family
BT246_RS04820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT246_RS04820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BT246_RS04825	COG0425	Belongs to the sulfur carrier protein TusA family
BT246_RS04830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BT246_RS04840	COG2210	Belongs to the sulfur carrier protein TusA family
BT246_RS04845	COG0730	response to heat
BT246_RS04855	COG1316	TRANSCRIPTIONal
BT246_RS04860	COG0604	alcohol dehydrogenase
BT246_RS04865	COG1283	sodium-dependent phosphate transmembrane transporter activity
BT246_RS04880	COG3584	3D domain protein
BT246_RS04880	COG1388	LysM domain
BT246_RS04885	COG0577	efflux transmembrane transporter activity
BT246_RS04890	COG1136	(ABC) transporter
BT246_RS04900	COG5522	Integral membrane protein (intg_mem_TP0381)
BT246_RS04915	COG1114	Component of the transport system for branched-chain amino acids
BT246_RS04920	COG3546	catalase activity
BT246_RS04955	COG0586	Pfam SNARE associated Golgi protein
BT246_RS04985	COG0531	amino acid
BT246_RS04990	COG0475	glutathione-regulated potassium exporter activity
BT246_RS05000	COG1737	Transcriptional regulator
BT246_RS05005	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS05015	COG1263	PTS System
BT246_RS05015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BT246_RS05025	COG2259	Doxx family
BT246_RS05045	COG1522	sequence-specific DNA binding
BT246_RS05050	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BT246_RS05050	COG0165	Argininosuccinate lyase
BT246_RS05055	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS05075	COG1309	transcriptional regulator
BT246_RS05080	COG2814	Major facilitator Superfamily
BT246_RS05085	COG1733	regulation of RNA biosynthetic process
BT246_RS05105	COG0693	protein deglycase activity
BT246_RS05110	COG0753	catalase activity
BT246_RS05110	COG0693	protein deglycase activity
BT246_RS05120	COG0531	amino acid
BT246_RS05135	COG1012	belongs to the aldehyde dehydrogenase family
BT246_RS05140	COG1132	(ABC) transporter
BT246_RS05145	COG1132	(ABC) transporter
BT246_RS05150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BT246_RS05155	COG0765	amino acid transport
BT246_RS05160	COG1126	abc transporter atp-binding protein
BT246_RS05175	COG0189	ligase activity
BT246_RS05225	COG0028	Belongs to the TPP enzyme family
BT246_RS05230	COG3527	Alpha-acetolactate decarboxylase
BT246_RS05245	COG0561	phosphatase activity
BT246_RS05260	COG5632	N-Acetylmuramoyl-L-alanine amidase
BT246_RS05260	COG3409	Peptidoglycan-binding domain 1 protein
BT246_RS05265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BT246_RS05270	COG0318	PFAM AMP-dependent synthetase and ligase
BT246_RS05285	COG0659	secondary active sulfate transmembrane transporter activity
BT246_RS05290	COG2244	polysaccharide biosynthetic process
BT246_RS05310	COG1024	Enoyl-CoA hydratase
BT246_RS05330	COG1363	Peptidase, m42
BT246_RS05375	COG0601	transmembrane transport
BT246_RS05380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BT246_RS05385	COG0444	Belongs to the ABC transporter superfamily
BT246_RS05390	COG4608	Belongs to the ABC transporter superfamily
BT246_RS05410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT246_RS05440	COG3290	protein histidine kinase activity
BT246_RS05445	COG4565	transcriptional regulatory protein
BT246_RS05450	COG3181	Tripartite tricarboxylate transporter family receptor
BT246_RS05480	COG0305	Participates in initiation and elongation during chromosome replication
BT246_RS05510	COG0477	Major facilitator Superfamily
BT246_RS05535	COG1073	alpha beta
BT246_RS05585	COG1183	phosphatidylcholine synthase activity
BT246_RS05595	COG2814	Major facilitator Superfamily
BT246_RS05600	COG0640	Transcriptional regulator
BT246_RS05610	COG2376	Dihydroxyacetone kinase
BT246_RS05620	COG2376	Dihydroxyacetone kinase
BT246_RS05660	COG0457	Tetratricopeptide repeat
BT246_RS05665	COG2373	Large extracellular alpha-helical protein
BT246_RS05695	COG0596	Alpha beta hydrolase
BT246_RS05720	COG3237	CsbD-like
BT246_RS05745	COG1191	sigma factor activity
BT246_RS05755	COG2208	phosphoserine phosphatase activity
BT246_RS05760	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BT246_RS05765	COG0784	Response regulator, receiver
BT246_RS05765	COG2198	Histidine kinase
BT246_RS05765	COG2205	protein histidine kinase activity
BT246_RS05800	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BT246_RS05820	COG0420	3'-5' exonuclease activity
BT246_RS05825	COG4717	serine-type aminopeptidase activity
BT246_RS05840	COG1280	lysine exporter protein (LysE YggA)
BT246_RS05845	COG0346	lactoylglutathione lyase activity
BT246_RS05850	COG0346	lactoylglutathione lyase activity
BT246_RS05860	COG0457	Tetratricopeptide repeat
BT246_RS05870	COG2267	carboxylic ester hydrolase activity
BT246_RS05885	COG2140	Oxalate decarboxylase
BT246_RS05890	COG3620	sequence-specific DNA binding
BT246_RS05895	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BT246_RS05900	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BT246_RS05910	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BT246_RS05915	COG1595	DNA-templated transcription, initiation
BT246_RS05925	COG0772	Belongs to the SEDS family
BT246_RS05930	COG3973	AAA domain
BT246_RS05960	COG4980	gas vesicle protein
BT246_RS05965	COG0537	adenosine 5'-monophosphoramidase activity
BT246_RS05970	COG1131	(ABC) transporter
BT246_RS05975	COG4473	ABC transporter
BT246_RS05985	COG1309	transcriptional regulator
BT246_RS05995	COG3402	PFAM membrane-flanked domain
BT246_RS06000	COG3428	Bacterial PH domain
BT246_RS06065	COG0697	spore germination
BT246_RS06070	COG3402	PFAM membrane-flanked domain
BT246_RS06075	COG3428	Bacterial PH domain
BT246_RS06080	COG2329	Antibiotic biosynthesis monooxygenase
BT246_RS06085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BT246_RS06100	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BT246_RS06135	COG1309	transcriptional regulator
BT246_RS06140	COG1511	domain protein
BT246_RS06140	COG1511	domain protein
BT246_RS06170	COG1609	Transcriptional regulator
BT246_RS06180	COG1234	tRNA 3'-trailer cleavage
BT246_RS06185	COG0095	Lipoate-protein ligase
BT246_RS06195	COG0318	PFAM AMP-dependent synthetase and ligase
BT246_RS06205	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BT246_RS06215	COG4208	sulfate ABC transporter
BT246_RS06235	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS06295	COG1408	metallophosphoesterase
BT246_RS06300	COG1078	dGTPase activity
BT246_RS06310	COG1595	DNA-templated transcription, initiation
BT246_RS06315	COG3708	Transcriptional regulator
BT246_RS06315	COG2207	Transcriptional regulator
BT246_RS06325	COG2205	protein histidine kinase activity
BT246_RS06330	COG0745	RESPONSE REGULATOR receiver
BT246_RS06350	COG0501	Belongs to the peptidase M48B family
BT246_RS06355	COG0840	transmembrane signaling receptor activity
BT246_RS06360	COG3693	PFAM glycoside hydrolase, family 10
BT246_RS06370	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BT246_RS06375	COG2224	Isocitrate lyase
BT246_RS06390	COG1278	Cold shock
BT246_RS06410	COG0398	Pfam SNARE associated Golgi protein
BT246_RS06430	COG0202	RNA polymerase activity
BT246_RS06470	COG0179	Fumarylacetoacetate (FAA) hydrolase
BT246_RS06495	COG0367	asparagine synthase
BT246_RS06725	COG0753	catalase activity
BT246_RS06730	COG0004	ammonium transporteR
BT246_RS06750	COG2996	Protein conserved in bacteria
BT246_RS06765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT246_RS06780	COG0561	phosphatase activity
BT246_RS06800	COG2267	carboxylic ester hydrolase activity
BT246_RS06815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BT246_RS06820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BT246_RS06825	COG5504	Zn-dependent protease
BT246_RS06835	COG0180	Tryptophanyl-tRNA synthetase
BT246_RS06845	COG4166	transmembrane transport
BT246_RS06850	COG0601	transmembrane transport
BT246_RS06855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BT246_RS06860	COG0444	Belongs to the ABC transporter superfamily
BT246_RS06865	COG4608	Belongs to the ABC transporter superfamily
BT246_RS06870	COG0534	Mate efflux family protein
BT246_RS06875	COG4166	transmembrane transport
BT246_RS06890	COG0861	Integral membrane protein TerC family
BT246_RS06900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BT246_RS06910	COG1164	Oligoendopeptidase f
BT246_RS06920	COG2346	COG2346, Truncated hemoglobins
BT246_RS06925	COG4116	CYTH
BT246_RS06935	COG2357	RelA SpoT domain protein
BT246_RS06945	COG0564	pseudouridine synthase activity
BT246_RS06960	COG0772	Belongs to the SEDS family
BT246_RS06965	COG1216	Glycosyl transferase, family 2
BT246_RS06985	COG0457	Tetratricopeptide repeat
BT246_RS06985	COG0463	Glycosyl transferase, family 2
BT246_RS07010	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BT246_RS07025	COG1091	dTDP-4-dehydrorhamnose reductase activity
BT246_RS07070	COG2153	protein acetylation
BT246_RS07080	COG2382	esterase
BT246_RS07100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BT246_RS07110	COG0512	Glutamine amidotransferase of anthranilate synthase
BT246_RS07110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BT246_RS07145	COG1620	l-lactate permease
BT246_RS07150	COG5634	Uncharacterized conserved protein (DUF2278)
BT246_RS07195	COG2226	methyltransferase
BT246_RS07215	COG0508	dehydrogenase complex catalyzes the overall conversion of
BT246_RS07225	COG1476	TRANSCRIPTIONal
BT246_RS07265	COG4152	abc transporter atp-binding protein
BT246_RS07270	COG1668	transmembrane transport
BT246_RS07290	COG2226	methyltransferase
BT246_RS07300	COG1686	Belongs to the peptidase S11 family
BT246_RS07305	COG0681	Belongs to the peptidase S26 family
BT246_RS07340	COG1012	belongs to the aldehyde dehydrogenase family
BT246_RS07350	COG1176	ABC-type spermidine putrescine transport system, permease component I
BT246_RS07355	COG1177	transmembrane transport
BT246_RS07370	COG2409	Drug exporters of the RND superfamily
BT246_RS07380	COG0564	pseudouridine synthase activity
BT246_RS07390	COG2340	Cysteine-rich secretory protein family
BT246_RS07395	COG0247	lactate metabolic process
BT246_RS07400	COG0277	FAD linked oxidase domain protein
BT246_RS07405	COG3835	regulator
BT246_RS07415	COG0745	RESPONSE REGULATOR receiver
BT246_RS07420	COG5002	protein histidine kinase activity
BT246_RS07425	COG2186	Transcriptional regulator
BT246_RS07445	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BT246_RS07455	COG2116	formate transmembrane transporter activity
BT246_RS07460	COG0861	Integral membrane protein TerC family
BT246_RS07465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BT246_RS07475	COG2030	dehydratase
BT246_RS07495	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS07500	COG3243	poly(R)-hydroxyalkanoic acid synthase
BT246_RS07510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BT246_RS07525	COG1840	ABC-type Fe3 transport system, periplasmic component
BT246_RS07530	COG3842	ATPase activity
BT246_RS07555	COG1349	DNA-binding transcription factor activity
BT246_RS07570	COG0235	Class ii aldolase
BT246_RS07580	COG2861	carbohydrate metabolic process
BT246_RS07590	COG3852	Histidine kinase
BT246_RS07595	COG1846	Transcriptional regulator
BT246_RS07605	COG2318	DinB family
BT246_RS07615	COG5002	protein histidine kinase activity
BT246_RS07625	COG0720	synthase
BT246_RS07640	COG4873	Protein conserved in bacteria
BT246_RS07670	COG1780	Probably involved in ribonucleotide reductase function
BT246_RS07675	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BT246_RS07680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BT246_RS07685	COG1725	Transcriptional regulator
BT246_RS07690	COG1131	(ABC) transporter
BT246_RS07700	COG1131	(ABC) transporter
BT246_RS07705	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BT246_RS07720	COG1522	sequence-specific DNA binding
BT246_RS07730	COG1335	isochorismatase
BT246_RS07740	COG1619	proteins homologs of microcin C7 resistance protein MccF
BT246_RS07745	COG2070	2-Nitropropane dioxygenase
BT246_RS07750	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BT246_RS07760	COG1696	Membrane protein involved in D-alanine export
BT246_RS07785	COG0716	FMN binding
BT246_RS07810	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS07850	COG1846	Transcriptional regulator
BT246_RS07860	COG1301	dicarboxylic acid transport
BT246_RS07865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BT246_RS07870	COG4709	membrane
BT246_RS07875	COG3874	Sporulation protein YtfJ
BT246_RS07895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BT246_RS07900	COG0028	Belongs to the TPP enzyme family
BT246_RS07905	COG0440	acetolactate synthase activity
BT246_RS07980	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BT246_RS07995	COG1183	phosphatidylcholine synthase activity
BT246_RS08000	COG1368	sulfuric ester hydrolase activity
BT246_RS08010	COG0019	diaminopimelate decarboxylase activity
BT246_RS08030	COG0529	Catalyzes the synthesis of activated sulfate
BT246_RS08035	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BT246_RS08055	COG1648	precorrin-2 dehydrogenase activity
BT246_RS08060	COG0733	neurotransmitter:sodium symporter activity
BT246_RS08080	COG1757	Na H antiporter
BT246_RS08095	COG4758	membrane
BT246_RS08100	COG4585	Histidine kinase
BT246_RS08105	COG2197	response regulator
BT246_RS08115	COG1114	Component of the transport system for branched-chain amino acids
BT246_RS08165	COG0730	response to heat
BT246_RS08170	COG0306	phosphate transporter
BT246_RS08175	COG1392	Phosphate transport regulator
BT246_RS08180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BT246_RS08195	COG3852	Histidine kinase
BT246_RS08200	COG1801	Protein of unknown function DUF72
BT246_RS08210	COG0582	viral genome integration into host DNA
BT246_RS08215	COG5002	protein histidine kinase activity
BT246_RS08230	COG0392	lysyltransferase activity
BT246_RS08230	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BT246_RS08245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BT246_RS08250	COG1686	Belongs to the peptidase S11 family
BT246_RS08255	COG2715	membrane protein required for spore maturation
BT246_RS08260	COG0700	Nucleoside recognition
BT246_RS08265	COG1187	pseudouridine synthase activity
BT246_RS08275	COG1333	cytochrome c biogenesis protein
BT246_RS08280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BT246_RS08285	COG0745	RESPONSE REGULATOR receiver
BT246_RS08290	COG5002	protein histidine kinase activity
BT246_RS08295	COG2096	Adenosyltransferase
BT246_RS08310	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BT246_RS08315	COG1141	Ferredoxin
BT246_RS08325	COG0514	ATP-dependent DNA helicase (RecQ)
BT246_RS08330	COG1266	CAAX protease self-immunity
BT246_RS08340	COG1408	metallophosphoesterase
BT246_RS08345	COG0789	Transcriptional regulator
BT246_RS08355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BT246_RS08375	COG0492	ferredoxin-NADP+ reductase activity
BT246_RS08380	COG0252	asparaginase activity
BT246_RS08445	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BT246_RS08460	COG0142	geranyltranstransferase activity
BT246_RS08470	COG0142	geranyltranstransferase activity
BT246_RS08495	COG0457	Tetratricopeptide repeat
BT246_RS08515	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BT246_RS08520	COG2010	Cytochrome c
BT246_RS08520	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BT246_RS08525	COG4347	Protein of unknown function (DUF1405)
BT246_RS08540	COG2738	Putative neutral zinc metallopeptidase
BT246_RS08550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT246_RS08555	COG1694	Mazg nucleotide pyrophosphohydrolase
BT246_RS08575	COG0438	transferase activity, transferring glycosyl groups
BT246_RS08610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BT246_RS08610	COG1199	ATP-dependent helicase activity
BT246_RS08630	COG3935	DnaD domain protein
BT246_RS08635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BT246_RS08645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BT246_RS08645	COG4499	WXG100 protein secretion system (Wss), protein YukC
BT246_RS08700	COG0116	Belongs to the methyltransferase superfamily
BT246_RS08710	COG1199	ATP-dependent helicase activity
BT246_RS08715	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BT246_RS08735	COG2233	PERMEase
BT246_RS08740	COG2311	Membrane
BT246_RS08745	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BT246_RS08755	COG0456	acetyltransferase
BT246_RS08805	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BT246_RS08820	COG3944	biosynthesis protein
BT246_RS08830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BT246_RS08845	COG1215	transferase activity, transferring glycosyl groups
BT246_RS08850	COG0438	transferase activity, transferring glycosyl groups
BT246_RS08865	COG0454	-acetyltransferase
BT246_RS08885	COG0328	RNA-DNA hybrid ribonuclease activity
BT246_RS08920	COG3403	YqcI/YcgG family
BT246_RS08925	COG1280	lysine exporter protein (LysE YggA)
BT246_RS08945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BT246_RS08950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BT246_RS08960	COG0475	glutathione-regulated potassium exporter activity
BT246_RS08965	COG0789	Transcriptional regulator
BT246_RS08965	COG4978	Transcriptional regulator
BT246_RS08975	COG2323	membrane
BT246_RS08980	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BT246_RS09030	COG1923	regulation of RNA biosynthetic process
BT246_RS09040	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BT246_RS09045	COG1360	Flagellar Motor Protein
BT246_RS09050	COG2201	protein-glutamate methylesterase activity
BT246_RS09055	COG2198	Histidine kinase
BT246_RS09055	COG0643	Histidine kinase
BT246_RS09060	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BT246_RS09060	COG1776	CheC inhibitor of MCP methylation
BT246_RS09075	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BT246_RS09095	COG1256	bacterial-type flagellum assembly
BT246_RS09100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BT246_RS09125	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BT246_RS09140	COG1815	bacterial-type flagellum-dependent cell motility
BT246_RS09145	COG1558	bacterial-type flagellum-dependent cell motility
BT246_RS09155	COG1766	The M ring may be actively involved in energy transduction
BT246_RS09160	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BT246_RS09170	COG1157	protein secretion by the type III secretion system
BT246_RS09205	COG0835	chemotaxis
BT246_RS09205	COG0784	Response regulator, receiver
BT246_RS09215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BT246_RS09220	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BT246_RS09225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BT246_RS09230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BT246_RS09235	COG0741	lytic transglycosylase activity
BT246_RS09245	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BT246_RS09250	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BT246_RS09250	COG1776	CheC inhibitor of MCP methylation
BT246_RS09260	COG1338	Plays a role in the flagellum-specific transport system
BT246_RS09265	COG1987	bacterial-type flagellum assembly
BT246_RS09275	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BT246_RS09280	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BT246_RS09285	COG1419	protein localization to endoplasmic reticulum
BT246_RS09290	COG4786	Flagellar basal body rod
BT246_RS09295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BT246_RS09335	COG2329	Antibiotic biosynthesis monooxygenase
BT246_RS09360	COG0583	DNA-binding transcription factor activity
BT246_RS09365	COG3842	ATPase activity
BT246_RS09380	COG1234	tRNA 3'-trailer cleavage
BT246_RS09415	COG0406	alpha-ribazole phosphatase activity
BT246_RS09445	COG0367	asparagine synthase
BT246_RS09475	COG1802	Transcriptional regulator
BT246_RS09480	COG0697	spore germination
BT246_RS09490	COG0523	cobalamin synthesis protein
BT246_RS09495	COG0701	Predicted permease
BT246_RS09510	COG1757	Na H antiporter
BT246_RS09515	COG0789	Transcriptional regulator
BT246_RS09540	COG0534	Mate efflux family protein
BT246_RS09545	COG3340	Belongs to the peptidase S51 family
BT246_RS09565	COG0785	Cytochrome C biogenesis protein
BT246_RS09570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BT246_RS09580	COG0457	Tetratricopeptide repeat
BT246_RS09600	COG2733	membrane
BT246_RS09635	COG1131	(ABC) transporter
BT246_RS09650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BT246_RS09655	COG0528	UMP kinase activity
BT246_RS09670	COG1027	Aspartate ammonia-lyase
BT246_RS09675	COG0281	malic enzyme
BT246_RS09680	COG4191	Histidine kinase
BT246_RS09685	COG0784	Response regulator, receiver
BT246_RS09690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BT246_RS09745	COG2814	Major facilitator Superfamily
BT246_RS09765	COG1695	Transcriptional regulator
BT246_RS09775	COG0477	Major facilitator Superfamily
BT246_RS09790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BT246_RS09795	COG2223	nitrite transmembrane transporter activity
BT246_RS09800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BT246_RS09820	COG0733	neurotransmitter:sodium symporter activity
BT246_RS09830	COG5566	PFAM Mor transcription activator
BT246_RS09835	COG2323	membrane
BT246_RS09855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BT246_RS09865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BT246_RS09870	COG0028	Belongs to the TPP enzyme family
BT246_RS09895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BT246_RS09920	COG2814	Major facilitator Superfamily
BT246_RS09925	COG3384	dioxygenase
BT246_RS09935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BT246_RS09940	COG3279	Response regulator of the LytR AlgR family
BT246_RS09965	COG2814	Major facilitator Superfamily
BT246_RS09970	COG1309	transcriptional regulator
BT246_RS09975	COG4166	transmembrane transport
BT246_RS09980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT246_RS10005	COG1914	H( )-stimulated, divalent metal cation uptake system
BT246_RS10020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BT246_RS10030	COG0531	amino acid
BT246_RS10060	COG2309	aminopeptidase activity
BT246_RS10075	COG0456	acetyltransferase
BT246_RS10085	COG1266	CAAX protease self-immunity
BT246_RS10090	COG1309	transcriptional regulator
BT246_RS10095	COG2390	Transcriptional regulator
BT246_RS10105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT246_RS10110	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BT246_RS10120	COG4846	Membrane protein involved in cytochrome C biogenesis
BT246_RS10170	COG0006	proline dipeptidase activity
BT246_RS10180	COG2132	Multicopper oxidase
BT246_RS10190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BT246_RS10210	COG1114	Component of the transport system for branched-chain amino acids
BT246_RS10220	COG2372	response to copper ion
BT246_RS10220	COG1276	copper resistance
BT246_RS10225	COG4549	nuclear export factor GLE1
BT246_RS10230	COG0697	spore germination
BT246_RS10235	COG0583	DNA-binding transcription factor activity
BT246_RS10240	COG1959	2 iron, 2 sulfur cluster binding
BT246_RS10245	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BT246_RS10250	COG0778	Nitroreductase
BT246_RS10265	COG0628	permease
BT246_RS10275	COG1231	oxidoreductase activity
BT246_RS10280	COG0523	cobalamin synthesis protein
BT246_RS10290	COG0411	ABC transporter
BT246_RS10310	COG0583	DNA-binding transcription factor activity
BT246_RS10320	COG1942	4-Oxalocrotonate Tautomerase
BT246_RS10340	COG1271	oxidase subunit
BT246_RS10345	COG1294	oxidase, subunit
BT246_RS10350	COG4988	ABC transporter
BT246_RS10355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BT246_RS10365	COG1216	Glycosyl transferase, family 2
BT246_RS10430	COG1132	(ABC) transporter
BT246_RS10435	COG0745	RESPONSE REGULATOR receiver
BT246_RS10440	COG5002	protein histidine kinase activity
BT246_RS10450	COG0300	oxidoreductase activity
BT246_RS10455	COG4122	O-methyltransferase activity
BT246_RS10490	COG0460	homoserine dehydrogenase
BT246_RS10515	COG1316	TRANSCRIPTIONal
BT246_RS10525	COG0745	RESPONSE REGULATOR receiver
BT246_RS10530	COG5002	protein histidine kinase activity
BT246_RS10545	COG1285	pathogenesis
BT246_RS10550	COG1247	-acetyltransferase
BT246_RS10570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BT246_RS10580	COG1082	Xylose isomerase domain protein TIM barrel
BT246_RS10590	COG2814	Major facilitator Superfamily
BT246_RS10595	COG1279	arginine transmembrane transporter activity
BT246_RS10600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT246_RS10610	COG1752	Esterase of the alpha-beta hydrolase superfamily
BT246_RS10645	COG0577	efflux transmembrane transporter activity
BT246_RS10650	COG2002	toxin-antitoxin pair type II binding
BT246_RS10655	COG1404	Belongs to the peptidase S8 family
BT246_RS10660	COG0640	Transcriptional regulator
BT246_RS10665	COG0667	Aldo Keto reductase
BT246_RS10670	COG2814	Major facilitator Superfamily
BT246_RS10695	COG0840	transmembrane signaling receptor activity
BT246_RS10710	COG3949	Membrane
BT246_RS10715	COG0783	Belongs to the Dps family
BT246_RS10720	COG0582	viral genome integration into host DNA
BT246_RS10725	COG1396	sequence-specific DNA binding
BT246_RS10765	COG5484	DNA packaging
BT246_RS10765	COG3728	DNA packaging
BT246_RS10795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BT246_RS10805	COG1231	oxidoreductase activity
BT246_RS10810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT246_RS10815	COG4989	oxidoreductase activity
BT246_RS10820	COG0523	cobalamin synthesis protein
BT246_RS10825	COG0456	acetyltransferase
BT246_RS10830	COG0803	Belongs to the bacterial solute-binding protein 9 family
BT246_RS10835	COG0702	epimerase
BT246_RS10845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BT246_RS10855	COG4166	transmembrane transport
BT246_RS10880	COG5337	Spore coat protein CotH
BT246_RS10885	COG1051	belongs to the nudix hydrolase family
BT246_RS10890	COG0586	Pfam SNARE associated Golgi protein
BT246_RS10895	COG2244	polysaccharide biosynthetic process
BT246_RS10905	COG0701	Predicted permease
BT246_RS10910	COG3689	TIGRFAM TIGR03943 family protein
BT246_RS10915	COG1607	acyl-coa hydrolase
BT246_RS10920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BT246_RS10935	COG0702	epimerase
BT246_RS10940	COG2839	Protein conserved in bacteria
BT246_RS10945	COG1253	flavin adenine dinucleotide binding
BT246_RS10970	COG1114	Component of the transport system for branched-chain amino acids
BT246_RS10975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BT246_RS10990	COG0860	N-Acetylmuramoyl-L-alanine amidase
BT246_RS11000	COG1876	peptidase activity
BT246_RS11015	COG2211	Major facilitator Superfamily
BT246_RS11030	COG0860	N-Acetylmuramoyl-L-alanine amidase
BT246_RS11040	COG0561	phosphatase activity
BT246_RS11045	COG1846	Transcriptional regulator
BT246_RS11050	COG2814	Major facilitator Superfamily
BT246_RS11060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BT246_RS11065	COG4106	trans-aconitate 2-methyltransferase activity
BT246_RS11080	COG1819	glycosyl
BT246_RS11085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT246_RS11090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT246_RS11120	COG0456	acetyltransferase
BT246_RS11165	COG3874	Sporulation protein YtfJ
BT246_RS11190	COG2226	methyltransferase
BT246_RS11210	COG1082	Xylose isomerase domain protein TIM barrel
BT246_RS11215	COG0346	lactoylglutathione lyase activity
BT246_RS11225	COG0604	alcohol dehydrogenase
BT246_RS11230	COG1595	DNA-templated transcription, initiation
BT246_RS11245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BT246_RS11245	COG0426	domain, Protein
BT246_RS11255	COG0386	Belongs to the glutathione peroxidase family
BT246_RS11260	COG1305	Transglutaminase-like
BT246_RS11265	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BT246_RS11270	COG0714	Associated with various cellular activities
BT246_RS11290	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BT246_RS11295	COG1140	nitrate reductase beta subunit
BT246_RS11300	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BT246_RS11305	COG2181	nitrate reductase activity
BT246_RS11310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BT246_RS11315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BT246_RS11320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BT246_RS11325	COG0303	'Molybdopterin
BT246_RS11330	COG0314	molybdopterin synthase activity
BT246_RS11340	COG2223	nitrite transmembrane transporter activity
BT246_RS11355	COG1648	precorrin-2 dehydrogenase activity
BT246_RS11365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BT246_RS11365	COG1587	Uroporphyrinogen-III synthase
BT246_RS11370	COG2146	nitrite reductase [NAD(P)H] activity
BT246_RS11375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BT246_RS11380	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BT246_RS11415	COG2359	stage V sporulation protein S
BT246_RS11435	COG1418	mRNA catabolic process
BT246_RS11440	COG0488	(ABC) transporter
BT246_RS11455	COG0629	single-stranded DNA binding
BT246_RS11465	COG1413	lyase activity
BT246_RS11480	COG2136	Putative SAM-dependent methyltransferase
BT246_RS11480	COG2521	methyltransferase
BT246_RS11485	COG0018	arginyl-trna synthetase
BT246_RS11530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BT246_RS11535	COG0017	Asparaginyl-tRNA synthetase
BT246_RS11540	COG0733	neurotransmitter:sodium symporter activity
BT246_RS11565	COG2610	gluconate transmembrane transporter activity
BT246_RS11575	COG1794	racemase activity, acting on amino acids and derivatives
BT246_RS11585	COG0456	acetyltransferase
BT246_RS11595	COG3655	Transcriptional regulator
BT246_RS11600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BT246_RS11610	COG1131	(ABC) transporter
BT246_RS11615	COG4473	ABC transporter
BT246_RS11625	COG0546	phosphoglycolate phosphatase activity
BT246_RS11650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BT246_RS11665	COG0768	penicillin binding
BT246_RS11675	COG0204	Acyl-transferase
BT246_RS11680	COG1272	protein, Hemolysin III
BT246_RS11690	COG0805	protein transport
BT246_RS11700	COG1307	EDD domain protein, DegV family
BT246_RS11710	COG1999	signal sequence binding
BT246_RS11715	COG0071	Belongs to the small heat shock protein (HSP20) family
BT246_RS11720	COG0367	asparagine synthase
BT246_RS11735	COG0860	N-Acetylmuramoyl-L-alanine amidase
BT246_RS11740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT246_RS11750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BT246_RS11770	COG1335	isochorismatase
BT246_RS11785	COG4585	Histidine kinase
BT246_RS11785	COG2203	Gaf domain
BT246_RS11790	COG2197	response regulator
BT246_RS11795	COG1737	Transcriptional regulator
BT246_RS11800	COG0384	phenazine biosynthesis protein PhzF
BT246_RS11805	COG1064	alcohol dehydrogenase
BT246_RS11820	COG1070	Carbohydrate kinase
BT246_RS11830	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BT246_RS11865	COG0517	IMP dehydrogenase activity
BT246_RS11865	COG1125	glycine betaine transport
BT246_RS11870	COG1174	glycine betaine transport
BT246_RS11905	COG1253	flavin adenine dinucleotide binding
BT246_RS11910	COG1012	belongs to the aldehyde dehydrogenase family
BT246_RS11915	COG5506	Protein of unknown function (DUF1694)
BT246_RS11930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BT246_RS11935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BT246_RS11940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BT246_RS11945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BT246_RS11950	COG0456	acetyltransferase
BT246_RS11955	COG3829	transcription factor binding
BT246_RS11960	COG1509	lysine 2,3-aminomutase activity
BT246_RS11995	COG0515	serine threonine protein kinase
BT246_RS11995	COG3064	Membrane
BT246_RS11995	COG4991	sh3 domain protein
BT246_RS12005	COG0671	phosphoesterase, PA-phosphatase related
BT246_RS12010	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BT246_RS12015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BT246_RS12095	COG0300	oxidoreductase activity
BT246_RS12115	COG4499	WXG100 protein secretion system (Wss), protein YukC
BT246_RS12115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BT246_RS12125	COG2814	Major facilitator Superfamily
BT246_RS12130	COG4841	protein insertion into membrane
BT246_RS12135	COG0372	Belongs to the citrate synthase family
BT246_RS12140	COG2079	MmgE PrpD family protein
BT246_RS12145	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BT246_RS12150	COG1960	acyl-CoA dehydrogenase activity
BT246_RS12155	COG2084	Dehydrogenase
BT246_RS12165	COG1280	lysine exporter protein (LysE YggA)
BT246_RS12170	COG1024	Enoyl-CoA hydratase
BT246_RS12185	COG0420	3'-5' exonuclease activity
BT246_RS12190	COG0419	ATPase involved in DNA repair
BT246_RS12210	COG2223	nitrite transmembrane transporter activity
BT246_RS12215	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS12220	COG1169	isochorismate synthase
BT246_RS12225	COG1021	2,3-dihydroxybenzoate-AMP ligase
BT246_RS12230	COG3433	isochorismatase activity
BT246_RS12230	COG1535	isochorismatase
BT246_RS12235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BT246_RS12240	COG3251	PFAM MbtH domain protein
BT246_RS12245	COG2814	Major facilitator Superfamily
BT246_RS12260	COG0776	regulation of translation
BT246_RS12270	COG2318	DinB family
BT246_RS12280	COG1115	amino acid carrier protein
BT246_RS12300	COG1187	pseudouridine synthase activity
BT246_RS12315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BT246_RS12320	COG1136	(ABC) transporter
BT246_RS12330	COG2814	Major facilitator Superfamily
BT246_RS12345	COG0028	Belongs to the TPP enzyme family
BT246_RS12355	COG1234	tRNA 3'-trailer cleavage
BT246_RS12380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BT246_RS12395	COG1846	Transcriptional regulator
BT246_RS12405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT246_RS12440	COG1247	-acetyltransferase
BT246_RS12465	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BT246_RS12475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT246_RS12505	COG0583	DNA-binding transcription factor activity
BT246_RS12510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BT246_RS12530	COG0583	DNA-binding transcription factor activity
BT246_RS12535	COG2258	MOSC domain
BT246_RS12550	COG1132	(ABC) transporter
BT246_RS12555	COG1132	(ABC) transporter
BT246_RS12580	COG1396	sequence-specific DNA binding
BT246_RS12625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BT246_RS12630	COG1595	DNA-templated transcription, initiation
BT246_RS12655	COG1649	PFAM Uncharacterised BCR, COG1649
BT246_RS12680	COG2971	BadF BadG BcrA BcrD
BT246_RS12700	COG1846	Transcriptional regulator
BT246_RS12750	COG2002	toxin-antitoxin pair type II binding
BT246_RS12805	COG0582	viral genome integration into host DNA
BT246_RS12835	COG3615	Tellurite resistance protein tehB
BT246_RS12835	COG0500	methyltransferase
BT246_RS12845	COG2226	methyltransferase
BT246_RS12850	COG3961	Belongs to the TPP enzyme family
BT246_RS12855	COG1846	Transcriptional regulator
BT246_RS12885	COG2195	Cleaves the N-terminal amino acid of tripeptides
BT246_RS12925	COG2002	toxin-antitoxin pair type II binding
BT246_RS12935	COG0730	response to heat
BT246_RS12940	COG0110	maltose O-acetyltransferase activity
BT246_RS12950	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS12955	COG1686	Belongs to the peptidase S11 family
BT246_RS12980	COG2814	Major facilitator Superfamily
BT246_RS12990	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS13010	COG5002	protein histidine kinase activity
BT246_RS13020	COG2267	carboxylic ester hydrolase activity
BT246_RS13075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BT246_RS13095	COG1278	Cold shock
BT246_RS13115	COG1329	Transcriptional regulator
BT246_RS13140	COG1280	lysine exporter protein (LysE YggA)
BT246_RS13155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BT246_RS13170	COG0768	penicillin binding
BT246_RS13175	COG1595	DNA-templated transcription, initiation
BT246_RS13185	COG0768	penicillin binding
BT246_RS13190	COG0768	penicillin binding
BT246_RS13200	COG1408	metallophosphoesterase
BT246_RS13210	COG1131	(ABC) transporter
BT246_RS13220	COG1309	transcriptional regulator
BT246_RS13235	COG1960	acyl-CoA dehydrogenase activity
BT246_RS13240	COG0439	Biotin carboxylase
BT246_RS13245	COG0511	ligase activity, forming carbon-carbon bonds
BT246_RS13250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BT246_RS13255	COG1024	Enoyl-CoA hydratase
BT246_RS13260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BT246_RS13265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BT246_RS13295	COG1686	Belongs to the peptidase S11 family
BT246_RS13335	COG3227	Zinc metalloprotease (Elastase)
BT246_RS13340	COG2207	Transcriptional regulator
BT246_RS13370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BT246_RS13380	COG2814	Major facilitator Superfamily
BT246_RS13385	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS13390	COG1733	regulation of RNA biosynthetic process
BT246_RS13415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BT246_RS13435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT246_RS13445	COG2368	4-hydroxyphenylacetate
BT246_RS13470	COG2323	membrane
BT246_RS13480	COG0693	protein deglycase activity
BT246_RS13490	COG3386	PFAM SMP-30 Gluconolaconase
BT246_RS13500	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BT246_RS13505	COG3773	Cell wall hydrolase
BT246_RS13530	COG0745	RESPONSE REGULATOR receiver
BT246_RS13535	COG2205	protein histidine kinase activity
BT246_RS13550	COG0488	(ABC) transporter
BT246_RS13565	COG1136	(ABC) transporter
BT246_RS13570	COG0577	efflux transmembrane transporter activity
BT246_RS13595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT246_RS13605	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BT246_RS13695	COG0561	phosphatase activity
BT246_RS13700	COG5002	protein histidine kinase activity
BT246_RS13715	COG1819	glycosyl
BT246_RS13720	COG1794	racemase activity, acting on amino acids and derivatives
BT246_RS13740	COG2205	protein histidine kinase activity
BT246_RS13820	COG1073	alpha beta
BT246_RS13825	COG0577	efflux transmembrane transporter activity
BT246_RS13830	COG1136	(ABC) transporter
BT246_RS13845	COG1522	sequence-specific DNA binding
BT246_RS13870	COG5002	protein histidine kinase activity
BT246_RS13875	COG0745	RESPONSE REGULATOR receiver
BT246_RS13880	COG1011	Hydrolase
BT246_RS13905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BT246_RS13945	COG0322	excinuclease ABC activity
BT246_RS13985	COG4667	esterase of the alpha-beta hydrolase superfamily
BT246_RS14010	COG3878	Protein conserved in bacteria
BT246_RS14065	COG2223	nitrite transmembrane transporter activity
BT246_RS14080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BT246_RS14115	COG0697	spore germination
BT246_RS14120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT246_RS14155	COG2814	Major facilitator Superfamily
BT246_RS14160	COG0789	Transcriptional regulator
BT246_RS14210	COG0768	penicillin binding
BT246_RS14215	COG0671	phosphoesterase, PA-phosphatase related
BT246_RS14220	COG0604	alcohol dehydrogenase
BT246_RS14225	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BT246_RS14260	COG1523	belongs to the glycosyl hydrolase 13 family
BT246_RS14280	COG3227	Zinc metalloprotease (Elastase)
BT246_RS14290	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS14295	COG0737	Belongs to the 5'-nucleotidase family
BT246_RS14310	COG0201	protein transport
BT246_RS14325	COG0697	spore germination
BT246_RS14330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT246_RS14340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BT246_RS14385	COG2959	enzyme of heme biosynthesis
BT246_RS14425	COG1309	transcriptional regulator
BT246_RS14465	COG3284	Transcriptional regulator
BT246_RS14495	COG1959	2 iron, 2 sulfur cluster binding
BT246_RS14510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BT246_RS14520	COG0022	dehydrogenase e1 component
BT246_RS14525	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BT246_RS14535	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS14540	COG0456	acetyltransferase
BT246_RS14540	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BT246_RS14590	COG4176	ABC-type proline glycine betaine transport system permease component
BT246_RS14595	COG4175	Glycine betaine
BT246_RS14595	COG0517	IMP dehydrogenase activity
BT246_RS14625	COG2153	protein acetylation
BT246_RS14630	COG3397	chitin binding
BT246_RS14635	COG1819	glycosyl
BT246_RS14650	COG2205	protein histidine kinase activity
BT246_RS14655	COG2226	methyltransferase
BT246_RS14660	COG2315	Protein conserved in bacteria
BT246_RS14725	COG0514	ATP-dependent DNA helicase (RecQ)
BT246_RS14755	COG4637	Psort location Cytoplasmic, score
BT246_RS14775	COG3397	chitin binding
BT246_RS14790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BT246_RS14795	COG1115	amino acid carrier protein
BT246_RS14800	COG1012	belongs to the aldehyde dehydrogenase family
BT246_RS14805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BT246_RS14820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BT246_RS14860	COG0586	Pfam SNARE associated Golgi protein
BT246_RS14870	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BT246_RS14875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT246_RS14880	COG4166	transmembrane transport
BT246_RS14890	COG4948	Mandelate Racemase Muconate Lactonizing
BT246_RS14950	COG3850	Histidine kinase
BT246_RS14950	COG5002	protein histidine kinase activity
BT246_RS14955	COG0745	RESPONSE REGULATOR receiver
BT246_RS14995	COG1164	Oligoendopeptidase f
BT246_RS15000	COG1307	EDD domain protein, DegV family
BT246_RS15035	COG2814	Major facilitator Superfamily
BT246_RS15045	COG1664	Polymer-forming cytoskeletal
BT246_RS15050	COG0789	Transcriptional regulator
BT246_RS15055	COG4533	DNA binding
BT246_RS15060	COG2814	Major facilitator Superfamily
BT246_RS15060	COG0477	Major facilitator Superfamily
BT246_RS15085	COG2261	transglycosylase associated protein
BT246_RS15100	COG2226	methyltransferase
BT246_RS15135	COG0436	Aminotransferase
BT246_RS15140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BT246_RS15150	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BT246_RS15200	COG0628	permease
BT246_RS15210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BT246_RS15235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BT246_RS15240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BT246_RS15295	COG2746	aminoglycoside 3-N-acetyltransferase activity
BT246_RS15305	COG0697	spore germination
BT246_RS15330	COG4912	Dna alkylation repair
BT246_RS15335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BT246_RS15340	COG0346	lactoylglutathione lyase activity
BT246_RS15345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT246_RS15380	COG0861	Integral membrane protein TerC family
BT246_RS15385	COG1368	sulfuric ester hydrolase activity
BT246_RS15390	COG0488	(ABC) transporter
BT246_RS15400	COG1309	transcriptional regulator
BT246_RS15415	COG0287	Prephenate dehydrogenase
BT246_RS15430	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BT246_RS15430	COG1605	Chorismate mutase
BT246_RS15470	COG3584	3D domain protein
BT246_RS15470	COG1388	LysM domain
BT246_RS15480	COG0277	FAD linked oxidase domain protein
BT246_RS15505	COG1879	ABC-type sugar transport system periplasmic component
BT246_RS15510	COG1172	Belongs to the binding-protein-dependent transport system permease family
BT246_RS15525	COG2390	Transcriptional regulator
BT246_RS15530	COG1070	Carbohydrate kinase
BT246_RS15565	COG2329	Antibiotic biosynthesis monooxygenase
BT246_RS15570	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS15585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT246_RS15600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BT246_RS15610	COG1414	Transcriptional regulator
BT246_RS15615	COG0833	amino acid
BT246_RS15630	COG3239	Fatty acid desaturase
BT246_RS15640	COG2720	vancomycin resistance protein
BT246_RS15645	COG1785	Belongs to the alkaline phosphatase family
BT246_RS15655	COG3655	Transcriptional regulator
BT246_RS15680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT246_RS15685	COG0346	lactoylglutathione lyase activity
BT246_RS15705	COG0714	Associated with various cellular activities
BT246_RS15730	COG0753	catalase activity
BT246_RS15775	COG0778	Nitroreductase
BT246_RS15780	COG1846	Transcriptional regulator
BT246_RS15800	COG4884	unkown
BT246_RS15800	COG3831	ATPase activity
BT246_RS15810	COG1136	(ABC) transporter
BT246_RS15810	COG0577	efflux transmembrane transporter activity
BT246_RS15840	COG0456	acetyltransferase
BT246_RS15855	COG0697	spore germination
BT246_RS15860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT246_RS15900	COG0730	response to heat
BT246_RS15905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT246_RS15910	COG0833	amino acid
BT246_RS15920	COG4335	DNA alkylation repair
BT246_RS15945	COG0577	efflux transmembrane transporter activity
BT246_RS15945	COG1136	(ABC) transporter
BT246_RS15980	COG0768	penicillin binding
BT246_RS16015	COG1984	allophanate hydrolase subunit 2
BT246_RS16020	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BT246_RS16025	COG1414	Transcriptional regulator
BT246_RS16035	COG3142	Participates in the control of copper homeostasis
BT246_RS16040	COG0640	Transcriptional regulator
BT246_RS16050	COG1960	acyl-CoA dehydrogenase activity
BT246_RS16060	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS16070	COG3314	Sporulation integral membrane protein YlbJ
BT246_RS16115	COG0574	Belongs to the PEP-utilizing enzyme family
BT246_RS16115	COG3848	Pyruvate phosphate dikinase
BT246_RS16120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT246_RS16130	COG5577	PFAM Coat F domain
BT246_RS16135	COG3403	YqcI/YcgG family
BT246_RS16145	COG1113	amino acid transport
BT246_RS16170	COG1063	alcohol dehydrogenase
BT246_RS16180	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BT246_RS16190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BT246_RS16205	COG0737	Belongs to the 5'-nucleotidase family
BT246_RS16210	COG2267	carboxylic ester hydrolase activity
BT246_RS16215	COG1335	isochorismatase
BT246_RS16235	COG0583	DNA-binding transcription factor activity
BT246_RS16240	COG1846	Transcriptional regulator
BT246_RS16255	COG0598	Magnesium transport protein CorA
BT246_RS16300	COG0697	spore germination
BT246_RS16320	COG0415	Belongs to the DNA photolyase family
BT246_RS16335	COG0288	reversible hydration of carbon dioxide
BT246_RS16345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BT246_RS16360	COG5609	conserved protein (DUF2294)
BT246_RS16370	COG0456	acetyltransferase
BT246_RS16375	COG1575	Belongs to the MenA family. Type 1 subfamily
BT246_RS16385	COG0798	PFAM Bile acid sodium symporter
BT246_RS16390	COG0346	lactoylglutathione lyase activity
BT246_RS16395	COG0640	Transcriptional regulator
BT246_RS16410	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS16425	COG2814	Major facilitator Superfamily
BT246_RS16435	COG3320	Male sterility
BT246_RS16435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BT246_RS16440	COG1309	transcriptional regulator
BT246_RS16465	COG2814	Major facilitator Superfamily
BT246_RS16470	COG1309	transcriptional regulator
BT246_RS16480	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BT246_RS16495	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BT246_RS16515	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS16520	COG1522	sequence-specific DNA binding
BT246_RS16535	COG0346	lactoylglutathione lyase activity
BT246_RS16570	COG0814	amino acid
BT246_RS16575	COG0583	DNA-binding transcription factor activity
BT246_RS16625	COG0745	RESPONSE REGULATOR receiver
BT246_RS16630	COG5002	protein histidine kinase activity
BT246_RS16630	COG3850	Histidine kinase
BT246_RS16670	COG1136	(ABC) transporter
BT246_RS16720	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BT246_RS16735	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BT246_RS16755	COG0577	efflux transmembrane transporter activity
BT246_RS16775	COG3850	Histidine kinase
BT246_RS16775	COG5002	protein histidine kinase activity
BT246_RS16795	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS16800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT246_RS16810	COG1619	proteins homologs of microcin C7 resistance protein MccF
BT246_RS16830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BT246_RS16850	COG0662	Cupin 2, conserved barrel domain protein
BT246_RS16875	COG3409	Peptidoglycan-binding domain 1 protein
BT246_RS16875	COG5632	N-Acetylmuramoyl-L-alanine amidase
BT246_RS16895	COG1876	peptidase activity
BT246_RS16900	COG2843	Capsule synthesis protein
BT246_RS16910	COG0477	Major facilitator Superfamily
BT246_RS16925	COG1846	Transcriptional regulator
BT246_RS16930	COG2814	Major facilitator Superfamily
BT246_RS16940	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BT246_RS16945	COG1131	(ABC) transporter
BT246_RS16965	COG2031	fatty acid transporter
BT246_RS16975	COG2249	NAD(P)H dehydrogenase (quinone) activity
BT246_RS17030	COG1288	antiporter activity
BT246_RS17035	COG2356	endonuclease I
BT246_RS17075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BT246_RS17095	COG1733	regulation of RNA biosynthetic process
BT246_RS17100	COG0778	Nitroreductase
BT246_RS17130	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS17140	COG1131	(ABC) transporter
BT246_RS17170	COG1011	Hydrolase
BT246_RS17175	COG2365	Tyrosine phosphatase family
BT246_RS17200	COG0346	lactoylglutathione lyase activity
BT246_RS17205	COG1940	carbohydrate kinase activity
BT246_RS17215	COG0110	maltose O-acetyltransferase activity
BT246_RS17230	COG0628	permease
BT246_RS17285	COG1253	flavin adenine dinucleotide binding
BT246_RS17290	COG0789	Transcriptional regulator
BT246_RS17305	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BT246_RS17330	COG0697	spore germination
BT246_RS17340	COG1357	PFAM Pentapeptide repeats (8 copies)
BT246_RS17345	COG3813	Protein conserved in bacteria
BT246_RS17350	COG2706	6-phosphogluconolactonase activity
BT246_RS17355	COG1070	Carbohydrate kinase
BT246_RS17370	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BT246_RS17375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BT246_RS17380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BT246_RS17385	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BT246_RS17390	COG0604	alcohol dehydrogenase
BT246_RS17395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BT246_RS17400	COG0789	Transcriptional regulator
BT246_RS17405	COG4221	oxidoreductase activity
BT246_RS17420	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS17455	COG0840	transmembrane signaling receptor activity
BT246_RS17465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BT246_RS17465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BT246_RS17470	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BT246_RS17470	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BT246_RS17475	COG1733	regulation of RNA biosynthetic process
BT246_RS17505	COG0656	L-ascorbic acid biosynthetic process
BT246_RS17520	COG0656	L-ascorbic acid biosynthetic process
BT246_RS17525	COG2814	Major facilitator Superfamily
BT246_RS17545	COG2824	Alkylphosphonate utilization operon protein PhnA
BT246_RS17550	COG0659	secondary active sulfate transmembrane transporter activity
BT246_RS17565	COG0814	amino acid
BT246_RS17605	COG1733	regulation of RNA biosynthetic process
BT246_RS17610	COG2188	Transcriptional regulator
BT246_RS17620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BT246_RS17625	COG1733	regulation of RNA biosynthetic process
BT246_RS17630	COG1733	regulation of RNA biosynthetic process
BT246_RS17655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT246_RS17680	COG0384	phenazine biosynthesis protein PhzF
BT246_RS17685	COG0318	PFAM AMP-dependent synthetase and ligase
BT246_RS17690	COG2249	NAD(P)H dehydrogenase (quinone) activity
BT246_RS17695	COG1733	regulation of RNA biosynthetic process
BT246_RS17705	COG0726	polysaccharide deacetylase
BT246_RS17715	COG1191	sigma factor activity
BT246_RS17725	COG1280	lysine exporter protein (LysE YggA)
BT246_RS17780	COG1151	hydroxylamine reductase activity
BT246_RS17790	COG3757	hydrolase, family 25
BT246_RS17790	COG3409	Peptidoglycan-binding domain 1 protein
BT246_RS17860	COG1113	amino acid transport
BT246_RS17865	COG2814	Major facilitator Superfamily
BT246_RS17895	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BT246_RS17900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BT246_RS17925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT246_RS17930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT246_RS17935	COG3739	integral membrane protein
BT246_RS17970	COG0583	DNA-binding transcription factor activity
BT246_RS17990	COG1193	negative regulation of DNA recombination
BT246_RS18005	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BT246_RS18010	COG1164	Oligoendopeptidase f
BT246_RS18035	COG3781	membrane
BT246_RS18050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BT246_RS18075	COG0584	glycerophosphoryl diester phosphodiesterase
BT246_RS18085	COG0640	Transcriptional regulator
BT246_RS18090	COG0604	alcohol dehydrogenase
BT246_RS18100	COG0457	Tetratricopeptide repeat
BT246_RS18110	COG2808	Putative FMN-binding domain
BT246_RS18125	COG0277	FAD linked oxidase domain protein
BT246_RS18140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BT246_RS18140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT246_RS18160	COG0584	glycerophosphoryl diester phosphodiesterase
BT246_RS18220	COG0697	spore germination
BT246_RS18240	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BT246_RS18250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BT246_RS18260	COG0457	Tetratricopeptide repeat
BT246_RS18285	COG1404	Belongs to the peptidase S8 family
BT246_RS18405	COG0740	serine-type endopeptidase activity
BT246_RS18415	COG1802	Transcriptional regulator
BT246_RS18415	COG4626	Terminase
BT246_RS18450	COG0582	viral genome integration into host DNA
BT246_RS18530	COG1396	sequence-specific DNA binding
BT246_RS18560	COG1876	peptidase activity
BT246_RS18620	COG3852	Histidine kinase
BT246_RS18630	COG1285	pathogenesis
BT246_RS18640	COG2514	catechol 2,3-dioxygenase activity
BT246_RS18645	COG2720	vancomycin resistance protein
BT246_RS18775	COG0582	viral genome integration into host DNA
BT246_RS18815	COG0270	DNA (cytosine-5-)-methyltransferase activity
BT246_RS18820	COG0270	DNA (cytosine-5-)-methyltransferase activity
BT246_RS18840	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BT246_RS18850	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BT246_RS18880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BT246_RS18880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BT246_RS18940	COG1484	DNA-dependent DNA replication
BT246_RS18995	COG0716	FMN binding
BT246_RS19025	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS19035	COG0165	Argininosuccinate lyase
BT246_RS19050	COG4145	pantothenate transmembrane transporter activity
BT246_RS19060	COG4145	pantothenate transmembrane transporter activity
BT246_RS19070	COG1012	belongs to the aldehyde dehydrogenase family
BT246_RS19075	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS19090	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BT246_RS19095	COG2962	Rard protein
BT246_RS19100	COG3326	Membrane
BT246_RS19115	COG0489	protein tyrosine kinase activity
BT246_RS19125	COG0314	molybdopterin synthase activity
BT246_RS19130	COG0303	'Molybdopterin
BT246_RS19135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BT246_RS19140	COG2116	formate transmembrane transporter activity
BT246_RS19150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BT246_RS19155	COG5609	conserved protein (DUF2294)
BT246_RS19160	COG2427	Protein of unknown function (DUF1641)
BT246_RS19165	COG3383	formate dehydrogenase (NAD+) activity
BT246_RS19275	COG0740	serine-type endopeptidase activity
BT246_RS19285	COG1802	Transcriptional regulator
BT246_RS19285	COG4626	Terminase
BT246_RS19320	COG0582	viral genome integration into host DNA
BT246_RS19355	COG1484	DNA-dependent DNA replication
BT246_RS19360	COG1846	Transcriptional regulator
BT246_RS19375	COG3646	Phage regulatory protein
BT246_RS19390	COG1396	sequence-specific DNA binding
BT246_RS19405	COG3383	formate dehydrogenase (NAD+) activity
BT246_RS19410	COG0697	spore germination
BT246_RS19460	COG2226	methyltransferase
BT246_RS19465	COG4166	transmembrane transport
BT246_RS19470	COG4166	transmembrane transport
BT246_RS19475	COG4166	transmembrane transport
BT246_RS19480	COG1316	TRANSCRIPTIONal
BT246_RS19490	COG1595	DNA-templated transcription, initiation
BT246_RS19500	COG1131	(ABC) transporter
BT246_RS19520	COG0673	inositol 2-dehydrogenase activity
BT246_RS19525	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BT246_RS19530	COG0187	DNA topoisomerase II activity
BT246_RS19535	COG1832	CoA-binding protein
BT246_RS19540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BT246_RS19545	COG0745	RESPONSE REGULATOR receiver
BT246_RS19565	COG4841	protein insertion into membrane
BT246_RS19570	COG0824	Thioesterase
BT246_RS19595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BT246_RS19605	COG2274	protein secretion by the type I secretion system
BT246_RS19610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BT246_RS19640	COG2211	Major facilitator Superfamily
BT246_RS19650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BT246_RS19665	COG0183	Belongs to the thiolase family
BT246_RS19670	COG0318	PFAM AMP-dependent synthetase and ligase
BT246_RS19675	COG1268	BioY protein
BT246_RS19680	COG0318	PFAM AMP-dependent synthetase and ligase
BT246_RS19690	COG5002	protein histidine kinase activity
BT246_RS19705	COG1136	(ABC) transporter
BT246_RS19720	COG1131	(ABC) transporter
BT246_RS19825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT246_RS19835	COG5002	protein histidine kinase activity
BT246_RS19840	COG0400	carboxylic ester hydrolase activity
BT246_RS19845	COG0346	lactoylglutathione lyase activity
BT246_RS19850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BT246_RS19855	COG0069	glutamate synthase activity
BT246_RS19860	COG1902	pentaerythritol trinitrate reductase activity
BT246_RS19865	COG1329	Transcriptional regulator
BT246_RS19870	COG0010	Belongs to the arginase family
BT246_RS19895	COG2226	methyltransferase
BT246_RS19920	COG4846	Membrane protein involved in cytochrome C biogenesis
BT246_RS19925	COG0785	Cytochrome C biogenesis protein
BT246_RS19935	COG1473	amidohydrolase
BT246_RS19945	COG1131	(ABC) transporter
BT246_RS19960	COG0583	DNA-binding transcription factor activity
BT246_RS19970	COG1346	cytolysis
BT246_RS19985	COG0730	response to heat
BT246_RS20010	COG1132	(ABC) transporter
BT246_RS20015	COG1132	(ABC) transporter
BT246_RS20050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BT246_RS20055	COG0737	Belongs to the 5'-nucleotidase family
BT246_RS20075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BT246_RS20095	COG1695	Transcriptional regulator
BT246_RS20100	COG0174	glutamine synthetase
BT246_RS20105	COG0789	Transcriptional regulator
BT246_RS20110	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BT246_RS20115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BT246_RS20120	COG2860	membrane
BT246_RS20130	COG0464	growth
BT246_RS20160	COG3584	3D domain protein
BT246_RS20160	COG1388	LysM domain
BT246_RS20165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BT246_RS20165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BT246_RS20165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BT246_RS20170	COG1105	Belongs to the carbohydrate kinase PfkB family
BT246_RS20175	COG1349	DNA-binding transcription factor activity
BT246_RS20180	COG1979	alcohol dehydrogenase
BT246_RS20185	COG2322	membrane
BT246_RS20200	COG1113	amino acid transport
BT246_RS20210	COG1408	metallophosphoesterase
BT246_RS20215	COG2116	formate transmembrane transporter activity
BT246_RS20230	COG2217	Heavy metal translocating P-type atpase
BT246_RS20235	COG2608	mercury ion transmembrane transporter activity
BT246_RS20240	COG1937	Protein conserved in bacteria
BT246_RS20250	COG2819	hydrolase of the alpha beta superfamily
BT246_RS20255	COG1120	ATPase activity
BT246_RS20260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT246_RS20265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT246_RS20270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT246_RS20275	COG0708	Exodeoxyribonuclease III
BT246_RS20280	COG2169	Transcriptional regulator
BT246_RS20285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BT246_RS20290	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BT246_RS20300	COG2364	Membrane
BT246_RS20315	COG2267	carboxylic ester hydrolase activity
BT246_RS20320	COG3300	MHYT domain
BT246_RS20320	COG5001	Diguanylate cyclase
BT246_RS20340	COG1086	Polysaccharide biosynthesis protein
BT246_RS20355	COG1346	cytolysis
BT246_RS20365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT246_RS20375	COG2188	Transcriptional regulator
BT246_RS20380	COG2723	6-phospho-beta-galactosidase activity
BT246_RS20390	COG1404	Belongs to the peptidase S8 family
BT246_RS20395	COG3773	Cell wall hydrolase
BT246_RS20405	COG1368	sulfuric ester hydrolase activity
BT246_RS20410	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BT246_RS20435	COG4550	Control of competence regulator ComK, YlbF/YmcA
BT246_RS20445	COG1013	pyruvate-flavodoxin oxidoreductase activity
BT246_RS20450	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BT246_RS20450	COG0674	pyruvate-flavodoxin oxidoreductase activity
BT246_RS20460	COG2359	stage V sporulation protein S
BT246_RS20465	COG1692	metallophosphoesterase
BT246_RS20490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BT246_RS20495	COG1426	Protein conserved in bacteria
BT246_RS20510	COG0300	oxidoreductase activity
BT246_RS20515	COG0612	Peptidase, M16
BT246_RS20520	COG0612	Peptidase, M16
BT246_RS20525	COG1079	Belongs to the binding-protein-dependent transport system permease family
BT246_RS20530	COG4603	Belongs to the binding-protein-dependent transport system permease family
BT246_RS20535	COG3845	ABC transporter
BT246_RS20540	COG1744	ABC transporter substrate-binding protein PnrA-like
BT246_RS20545	COG2188	Transcriptional regulator
BT246_RS20565	COG0740	serine-type endopeptidase activity
BT246_RS20570	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BT246_RS20580	COG0527	aspartate kinase activity
BT246_RS20585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BT246_RS20590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BT246_RS20595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BT246_RS20600	COG1873	PFAM PRC-barrel domain
BT246_RS20605	COG0612	Peptidase, M16
BT246_RS20610	COG0726	polysaccharide deacetylase
BT246_RS20625	COG0196	riboflavin kinase activity
BT246_RS20635	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BT246_RS20640	COG1550	Protein conserved in bacteria
BT246_RS20650	COG1358	cellular component organization or biogenesis
BT246_RS20655	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BT246_RS20660	COG0195	Participates in both transcription termination and antitermination
BT246_RS20680	COG0750	zinc metalloprotease
BT246_RS20690	COG4589	Belongs to the CDS family
BT246_RS20745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BT246_RS20750	COG0758	DNA mediated transformation
BT246_RS20755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BT246_RS20795	COG1837	Belongs to the UPF0109 family
BT246_RS20805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BT246_RS20815	COG0552	protein localization to endoplasmic reticulum
BT246_RS20820	COG1196	nuclear chromosome segregation
BT246_RS20830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BT246_RS20835	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS20840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BT246_RS20855	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BT246_RS20860	COG1461	Dihydroxyacetone kinase
BT246_RS20865	COG1302	Protein conserved in bacteria
BT246_RS20880	COG1564	THIamine pyrophosphokinase
BT246_RS20885	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BT246_RS20895	COG2815	serine threonine protein kinase
BT246_RS20895	COG0515	serine threonine protein kinase
BT246_RS20900	COG0631	protein serine/threonine phosphatase activity
BT246_RS20910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BT246_RS20910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BT246_RS20925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BT246_RS20930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BT246_RS20950	COG1561	YicC-like family, N-terminal region
BT246_RS20955	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BT246_RS20970	COG0006	proline dipeptidase activity
BT246_RS20990	COG3069	C4-dicarboxylate transmembrane transporter activity
BT246_RS21055	COG0564	pseudouridine synthase activity
BT246_RS21075	COG3599	regulation of cell shape
BT246_RS21080	COG2302	S4 RNA-binding domain
BT246_RS21085	COG0762	integral membrane protein
BT246_RS21095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BT246_RS21105	COG1873	PFAM PRC-barrel domain
BT246_RS21110	COG1191	sigma factor activity
BT246_RS21115	COG1191	sigma factor activity
BT246_RS21125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BT246_RS21130	COG0849	cell division
BT246_RS21150	COG0772	Belongs to the SEDS family
BT246_RS21170	COG0768	penicillin binding
BT246_RS21175	COG0768	penicillin binding
BT246_RS21195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BT246_RS21210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BT246_RS21215	COG1399	metal-binding, possibly nucleic acid-binding protein
BT246_RS21225	COG3480	Lon protease (S16) C-terminal proteolytic domain
BT246_RS21230	COG1752	Esterase of the alpha-beta hydrolase superfamily
BT246_RS21235	COG3314	Sporulation integral membrane protein YlbJ
BT246_RS21245	COG0742	ribosomal rna small subunit methyltransferase
BT246_RS21260	COG3679	Belongs to the UPF0342 family
BT246_RS21265	COG0406	alpha-ribazole phosphatase activity
BT246_RS21280	COG2340	Cysteine-rich secretory protein family
BT246_RS21295	COG3336	cytochrome c oxidase
BT246_RS21330	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BT246_RS21335	COG0772	Belongs to the SEDS family
BT246_RS21345	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BT246_RS21350	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BT246_RS21360	COG4896	Protein conserved in bacteria
BT246_RS21375	COG1217	gtp-binding protein TYPA
BT246_RS21385	COG0483	inositol monophosphate 1-phosphatase activity
BT246_RS21405	COG1982	Orn Lys Arg decarboxylase major
BT246_RS21455	COG0022	dehydrogenase e1 component
BT246_RS21460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BT246_RS21475	COG0561	phosphatase activity
BT246_RS21485	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BT246_RS21490	COG0569	domain protein
BT246_RS21510	COG0583	DNA-binding transcription factor activity
BT246_RS21515	COG0517	IMP dehydrogenase activity
BT246_RS21525	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BT246_RS21535	COG4703	Protein of unknown function (DUF1797)
BT246_RS21550	COG2200	EAL domain
BT246_RS21555	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS21560	COG1408	metallophosphoesterase
BT246_RS21605	COG2814	Major facilitator Superfamily
BT246_RS21625	COG3209	COG3209 Rhs family protein
BT246_RS21635	COG2205	protein histidine kinase activity
BT246_RS21645	COG0436	Aminotransferase
BT246_RS21650	COG1609	Transcriptional regulator
BT246_RS21655	COG3833	ABC-type maltose transport systems, permease component
BT246_RS21660	COG1175	transmembrane transport
BT246_RS21665	COG2182	Extracellular solute-binding protein
BT246_RS21680	COG2182	Extracellular solute-binding protein
BT246_RS21690	COG0366	Alpha amylase catalytic
BT246_RS21695	COG3842	ATPase activity
BT246_RS21735	COG0183	Belongs to the thiolase family
BT246_RS21770	COG1695	Transcriptional regulator
BT246_RS21775	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS21795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BT246_RS21800	COG0436	Aminotransferase
BT246_RS21835	COG2084	Dehydrogenase
BT246_RS21845	COG2199	diguanylate cyclase activity
BT246_RS21850	COG0778	Nitroreductase
BT246_RS21875	COG2190	(PTS) system
BT246_RS21875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BT246_RS21875	COG1263	PTS System
BT246_RS21880	COG3711	transcriptional antiterminator
BT246_RS21890	COG2188	Transcriptional regulator
BT246_RS21900	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BT246_RS21925	COG1547	Domain of unknown function (DUF309)
BT246_RS21930	COG0456	acetyltransferase
BT246_RS21935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BT246_RS21940	COG4086	secreted protein
BT246_RS21945	COG0561	phosphatase activity
BT246_RS21950	COG0697	spore germination
BT246_RS21965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BT246_RS21990	COG0733	neurotransmitter:sodium symporter activity
BT246_RS22010	COG1686	Belongs to the peptidase S11 family
BT246_RS22015	COG1725	Transcriptional regulator
BT246_RS22020	COG1131	(ABC) transporter
BT246_RS22040	COG1846	Transcriptional regulator
BT246_RS22055	COG0598	Magnesium transport protein CorA
BT246_RS22080	COG4974	Belongs to the 'phage' integrase family
BT246_RS22090	COG0735	belongs to the Fur family
BT246_RS22095	COG1300	Membrane
BT246_RS22115	COG0667	Aldo Keto reductase
BT246_RS22120	COG0656	L-ascorbic acid biosynthetic process
BT246_RS22125	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BT246_RS22125	COG0456	acetyltransferase
BT246_RS22135	COG1525	nuclease
BT246_RS22135	COG4085	toxin activity
BT246_RS22135	COG0737	Belongs to the 5'-nucleotidase family
BT246_RS22145	COG0596	Alpha beta hydrolase
BT246_RS22150	COG2056	Na+-H+ antiporter family
BT246_RS22155	COG1609	Transcriptional regulator
BT246_RS22160	COG0456	acetyltransferase
BT246_RS22165	COG1073	alpha beta
BT246_RS22180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BT246_RS22180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BT246_RS22185	COG0307	riboflavin synthase, alpha
BT246_RS22215	COG1073	alpha beta
BT246_RS22215	COG2226	methyltransferase
BT246_RS22230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BT246_RS22240	COG1757	Na H antiporter
BT246_RS22245	COG0737	Belongs to the 5'-nucleotidase family
BT246_RS22255	COG1522	sequence-specific DNA binding
BT246_RS22300	COG0300	oxidoreductase activity
BT246_RS22305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT246_RS22310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BT246_RS22315	COG1760	l-serine dehydratase
BT246_RS22320	COG1760	l-serine dehydratase
BT246_RS22345	COG1285	pathogenesis
BT246_RS22360	COG2195	Cleaves the N-terminal amino acid of tripeptides
BT246_RS22365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT246_RS22375	COG1376	ErfK ybiS ycfS ynhG family protein
BT246_RS22380	COG4129	membrane
BT246_RS22385	COG1126	abc transporter atp-binding protein
BT246_RS22390	COG0765	amino acid transport
BT246_RS22395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BT246_RS22415	COG2323	membrane
BT246_RS22420	COG0772	Belongs to the SEDS family
BT246_RS22425	COG0508	dehydrogenase complex catalyzes the overall conversion of
BT246_RS22430	COG0022	dehydrogenase e1 component
BT246_RS22435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BT246_RS22440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BT246_RS22455	COG0280	phosphate acetyltransferase
BT246_RS22460	COG3290	protein histidine kinase activity
BT246_RS22460	COG3829	transcription factor binding
BT246_RS22470	COG0584	glycerophosphoryl diester phosphodiesterase
BT246_RS22475	COG3093	addiction module antidote protein HigA
BT246_RS22490	COG0750	zinc metalloprotease
BT246_RS22495	COG0497	DNA recombination
BT246_RS22505	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BT246_RS22515	COG0142	geranyltranstransferase activity
BT246_RS22540	COG1302	Protein conserved in bacteria
BT246_RS22545	COG0439	Biotin carboxylase
BT246_RS22550	COG0511	ligase activity, forming carbon-carbon bonds
BT246_RS22590	COG3854	ATPases associated with a variety of cellular activities
BT246_RS22615	COG0006	proline dipeptidase activity
BT246_RS22630	COG3872	metal-dependent enzyme
BT246_RS22640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BT246_RS22675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BT246_RS22685	COG1609	Transcriptional regulator
BT246_RS22695	COG2076	Multidrug Resistance protein
BT246_RS22700	COG2076	Multidrug Resistance protein
BT246_RS22730	COG1131	(ABC) transporter
BT246_RS22735	COG1725	Transcriptional regulator
BT246_RS22765	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BT246_RS22825	COG4537	Required for transformation and DNA binding
BT246_RS22830	COG1459	type II secretion system
BT246_RS22835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BT246_RS22890	COG1410	methionine synthase
BT246_RS22890	COG0646	methionine synthase
BT246_RS22895	COG0646	methionine synthase
BT246_RS22895	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BT246_RS22900	COG0626	cystathionine gamma-synthase activity
BT246_RS22905	COG0626	cystathionine gamma-synthase activity
BT246_RS22925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT246_RS22935	COG1940	carbohydrate kinase activity
BT246_RS22945	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BT246_RS22950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BT246_RS22955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BT246_RS22960	COG0704	Plays a role in the regulation of phosphate uptake
BT246_RS22970	COG0573	inorganic phosphate transmembrane transporter activity
BT246_RS22975	COG0573	inorganic phosphate transmembrane transporter activity
BT246_RS22980	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BT246_RS22985	COG0768	penicillin binding
BT246_RS23010	COG2801	Transposase and inactivated derivatives
BT246_RS23240	COG0582	viral genome integration into host DNA
BT246_RS23245	COG0477	Major facilitator Superfamily
BT246_RS23250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BT246_RS23260	COG5521	maltodextrose utilization protein MalA
BT246_RS23280	COG0735	belongs to the Fur family
BT246_RS23285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BT246_RS23290	COG1121	(ABC) transporter
BT246_RS23295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT246_RS23325	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BT246_RS23330	COG2384	SAM-dependent methyltransferase
BT246_RS23340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BT246_RS23345	COG0358	DNA primase activity
BT246_RS23355	COG0517	IMP dehydrogenase activity
BT246_RS23370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BT246_RS23375	COG0295	cytidine deaminase activity
BT246_RS23380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BT246_RS23390	COG1480	7TM receptor with intracellular HD hydrolase
BT246_RS23395	COG1702	phosphate starvation-inducible protein PhoH
BT246_RS23415	COG1610	YqeY-like protein
BT246_RS23420	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BT246_RS23425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BT246_RS23430	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BT246_RS23460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BT246_RS23465	COG1733	regulation of RNA biosynthetic process
BT246_RS23490	COG1466	dna polymerase III delta subunit
BT246_RS23500	COG2333	competence protein COMEC
BT246_RS23500	COG0658	competence protein
BT246_RS23505	COG2131	deaminase
BT246_RS23510	COG1555	photosystem II stabilization
BT246_RS23510	COG1596	polysaccharide export
BT246_RS23515	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BT246_RS23520	COG2226	methyltransferase
BT246_RS23525	COG0799	negative regulation of ribosome biogenesis
BT246_RS23530	COG1713	HD superfamily hydrolase involved in NAD metabolism
BT246_RS23540	COG1534	Rna-binding protein
BT246_RS23550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BT246_RS23555	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BT246_RS23580	COG1595	DNA-templated transcription, initiation
BT246_RS23590	COG0778	Nitroreductase
BT246_RS23595	COG2357	RelA SpoT domain protein
BT246_RS23605	COG1785	Belongs to the alkaline phosphatase family
BT246_RS23615	COG2267	carboxylic ester hydrolase activity
BT246_RS23650	COG1404	Belongs to the peptidase S8 family
BT246_RS23655	COG3186	Phenylalanine-4-hydroxylase
BT246_RS23665	COG2514	catechol 2,3-dioxygenase activity
BT246_RS23675	COG2259	Doxx family
BT246_RS23715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT246_RS23725	COG1454	alcohol dehydrogenase
BT246_RS23725	COG1012	belongs to the aldehyde dehydrogenase family
BT246_RS23730	COG0626	cystathionine gamma-synthase activity
BT246_RS23735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BT246_RS23760	COG0768	penicillin binding
BT246_RS23775	COG0826	peptidase U32
BT246_RS23780	COG0826	peptidase U32
BT246_RS23785	COG4122	O-methyltransferase activity
BT246_RS23790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BT246_RS23805	COG4472	Bacterial protein of unknown function (DUF965)
BT246_RS23820	COG0628	permease
BT246_RS23840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BT246_RS23855	COG1104	cysteine desulfurase activity
BT246_RS23860	COG1959	2 iron, 2 sulfur cluster binding
BT246_RS23865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BT246_RS23875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BT246_RS23910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BT246_RS23920	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BT246_RS23920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BT246_RS23925	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BT246_RS23930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BT246_RS23930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BT246_RS23940	COG2244	polysaccharide biosynthetic process
BT246_RS23945	COG2323	membrane
BT246_RS23955	COG1862	Preprotein translocase
BT246_RS23985	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BT246_RS24020	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BT246_RS24025	COG1104	cysteine desulfurase activity
BT246_RS24030	COG1827	regulation of RNA biosynthetic process
BT246_RS24035	COG2258	MOSC domain
BT246_RS24040	COG0077	Prephenate dehydratase
BT246_RS24045	COG0577	efflux transmembrane transporter activity
BT246_RS24050	COG0577	efflux transmembrane transporter activity
BT246_RS24055	COG1136	(ABC) transporter
BT246_RS24060	COG5002	protein histidine kinase activity
BT246_RS24065	COG0745	RESPONSE REGULATOR receiver
BT246_RS24075	COG3290	protein histidine kinase activity
BT246_RS24085	COG2868	ribosomal protein
BT246_RS24095	COG1530	ribonuclease E activity
BT246_RS24100	COG1994	Peptidase M50
BT246_RS24105	COG0739	heme binding
BT246_RS24110	COG2894	cell division
BT246_RS24130	COG1077	Cell shape determining protein MreB Mrl
BT246_RS24150	COG0285	dihydrofolate synthase activity
BT246_RS24165	COG1388	LysM domain
BT246_RS24175	COG0113	porphobilinogen synthase activity
BT246_RS24180	COG1587	Uroporphyrinogen-III synthase
BT246_RS24190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BT246_RS24200	COG1846	Transcriptional regulator
BT246_RS24205	COG1764	response to oxidative stress
BT246_RS24220	COG0470	DNA polymerase III
BT246_RS24220	COG1067	ATP-dependent peptidase activity
BT246_RS24275	COG0622	Phosphoesterase
BT246_RS24290	COG5401	PFAM Sporulation and spore germination
BT246_RS24300	COG0477	Major facilitator Superfamily
BT246_RS24310	COG1309	transcriptional regulator
BT246_RS24320	COG2197	response regulator
BT246_RS24325	COG2233	PERMEase
BT246_RS24330	COG0402	S-adenosylhomocysteine deaminase activity
BT246_RS24335	COG1983	PspC domain protein
BT246_RS24340	COG1396	sequence-specific DNA binding
BT246_RS24345	COG0697	spore germination
BT246_RS24355	COG1959	2 iron, 2 sulfur cluster binding
BT246_RS24360	COG1668	transmembrane transport
BT246_RS24365	COG4152	abc transporter atp-binding protein
BT246_RS24370	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BT246_RS24375	COG1360	Flagellar Motor Protein
BT246_RS24380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BT246_RS24385	COG1876	peptidase activity
BT246_RS24390	COG0824	Thioesterase
BT246_RS24395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BT246_RS24400	COG1053	succinate dehydrogenase
BT246_RS24405	COG2009	succinate dehydrogenase
BT246_RS24410	COG1719	4-vinyl reductase, 4VR
BT246_RS24420	COG3118	belongs to the thioredoxin family
BT246_RS24425	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BT246_RS24430	COG2086	electron transfer activity
BT246_RS24435	COG1024	Enoyl-CoA hydratase
BT246_RS24440	COG1309	transcriptional regulator
BT246_RS24445	COG0318	PFAM AMP-dependent synthetase and ligase
BT246_RS24470	COG2318	DinB family
BT246_RS24495	COG1131	(ABC) transporter
BT246_RS24500	COG2205	protein histidine kinase activity
BT246_RS24505	COG0745	RESPONSE REGULATOR receiver
BT246_RS24515	COG4895	conserved protein (DUF2196)
BT246_RS24520	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BT246_RS24530	COG4509	Sortase family
BT246_RS24535	COG1120	ATPase activity
BT246_RS24550	COG5386	Cell surface protein
BT246_RS24560	COG5386	Cell surface protein
BT246_RS24565	COG1114	Component of the transport system for branched-chain amino acids
BT246_RS24570	COG1187	pseudouridine synthase activity
BT246_RS24580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BT246_RS24580	COG1796	DNA polymerase
BT246_RS24585	COG1286	toxin biosynthetic process
BT246_RS24620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BT246_RS24625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BT246_RS24635	COG1418	mRNA catabolic process
BT246_RS24655	COG2814	Major facilitator Superfamily
BT246_RS24660	COG1566	PFAM secretion protein HlyD family protein
BT246_RS24665	COG1309	transcriptional regulator
BT246_RS24670	COG1363	Peptidase, m42
BT246_RS24695	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BT246_RS24710	COG1484	DNA-dependent DNA replication
BT246_RS24715	COG3611	Membrane attachment protein
BT246_RS24725	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BT246_RS24730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BT246_RS24735	COG0237	dephospho-CoA kinase activity
BT246_RS24740	COG1971	Probably functions as a manganese efflux pump
BT246_RS24750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BT246_RS24750	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BT246_RS24755	COG5002	protein histidine kinase activity
BT246_RS24760	COG0745	RESPONSE REGULATOR receiver
BT246_RS24780	COG0538	isocitrate dehydrogenase activity
BT246_RS24785	COG0372	Belongs to the citrate synthase family
BT246_RS24795	COG0628	permease
BT246_RS24800	COG3030	protein affecting phage T7 exclusion by the F plasmid
BT246_RS24825	COG2186	Transcriptional regulator
BT246_RS24830	COG0281	malic enzyme
BT246_RS24835	COG0587	DNA-directed DNA polymerase activity
BT246_RS24850	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BT246_RS24865	COG4109	DRTGG domain
BT246_RS24880	COG0006	proline dipeptidase activity
BT246_RS24915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT246_RS24920	COG0662	Cupin 2, conserved barrel domain protein
BT246_RS24935	COG1028	Short-chain dehydrogenase reductase Sdr
BT246_RS24940	COG0589	response to stress
BT246_RS24975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT246_RS25005	COG0827	DNA restriction-modification system
BT246_RS25010	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BT246_RS25015	COG3874	Sporulation protein YtfJ
BT246_RS25030	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BT246_RS25040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BT246_RS25055	COG1104	cysteine desulfurase activity
BT246_RS25065	COG0583	DNA-binding transcription factor activity
BT246_RS25070	COG0697	spore germination
BT246_RS25075	COG1309	transcriptional regulator
BT246_RS25080	COG1956	GAF domain-containing protein
BT246_RS25085	COG0626	cystathionine gamma-synthase activity
BT246_RS25110	COG0110	maltose O-acetyltransferase activity
BT246_RS25115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BT246_RS25120	COG0454	-acetyltransferase
BT246_RS25125	COG0517	IMP dehydrogenase activity
BT246_RS25130	COG0123	including yeast histone deacetylase and acetoin utilization protein
BT246_RS25145	COG0745	RESPONSE REGULATOR receiver
BT246_RS25150	COG5002	protein histidine kinase activity
BT246_RS25155	COG0666	response to abiotic stimulus
BT246_RS25185	COG1609	Transcriptional regulator
BT246_RS25190	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BT246_RS25190	COG1605	Chorismate mutase
BT246_RS25195	COG1605	Chorismate mutase
BT246_RS25195	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BT246_RS25200	COG1605	Chorismate mutase
BT246_RS25200	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BT246_RS25205	COG4851	CamS sex pheromone cAM373 precursor
BT246_RS25210	COG3118	belongs to the thioredoxin family
BT246_RS25220	COG2309	aminopeptidase activity
BT246_RS25240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT246_RS25245	COG0697	spore germination
BT246_RS25250	COG0789	Transcriptional regulator
BT246_RS25265	COG1674	ftsk spoiiie
BT246_RS25270	COG0860	N-Acetylmuramoyl-L-alanine amidase
BT246_RS25280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BT246_RS25290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BT246_RS25295	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BT246_RS25300	COG1363	Peptidase, m42
BT246_RS25310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT246_RS25325	COG0510	thiamine kinase activity
BT246_RS25330	COG1523	belongs to the glycosyl hydrolase 13 family
BT246_RS25340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BT246_RS25345	COG1349	DNA-binding transcription factor activity
BT246_RS25350	COG1187	pseudouridine synthase activity
BT246_RS25355	COG2244	polysaccharide biosynthetic process
BT246_RS25360	COG2081	HI0933 family
BT246_RS25365	COG2814	Major facilitator Superfamily
BT246_RS25375	COG3832	glyoxalase III activity
BT246_RS25380	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS25400	COG1329	Transcriptional regulator
BT246_RS25425	COG0314	molybdopterin synthase activity
BT246_RS25430	COG1763	Mo-molybdopterin cofactor biosynthetic process
BT246_RS25435	COG0303	'Molybdopterin
BT246_RS25445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BT246_RS25450	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BT246_RS25470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BT246_RS25480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BT246_RS25520	COG2814	Major facilitator Superfamily
BT246_RS25525	COG0475	glutathione-regulated potassium exporter activity
BT246_RS25530	COG0490	domain, Protein
BT246_RS25535	COG0582	viral genome integration into host DNA
BT246_RS25545	COG1136	(ABC) transporter
BT246_RS25580	COG1242	4 iron, 4 sulfur cluster binding
BT246_RS25585	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BT246_RS25590	COG1131	(ABC) transporter
BT246_RS25600	COG1794	racemase activity, acting on amino acids and derivatives
BT246_RS25620	COG2267	carboxylic ester hydrolase activity
BT246_RS25625	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BT246_RS25630	COG0671	phosphoesterase, PA-phosphatase related
BT246_RS25635	COG0438	transferase activity, transferring glycosyl groups
BT246_RS25715	COG5002	protein histidine kinase activity
BT246_RS25720	COG3852	Histidine kinase
BT246_RS25725	COG0753	catalase activity
BT246_RS25740	COG2267	carboxylic ester hydrolase activity
BT246_RS25745	COG1368	sulfuric ester hydrolase activity
BT246_RS25760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BT246_RS25765	COG1116	anion transmembrane transporter activity
BT246_RS25770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BT246_RS25795	COG0494	nUDIX hydrolase
BT246_RS25825	COG2076	Multidrug Resistance protein
BT246_RS25830	COG2076	Multidrug Resistance protein
BT246_RS25835	COG0789	Transcriptional regulator
BT246_RS25840	COG1854	S-ribosylhomocysteine lyase activity
BT246_RS25850	COG0288	reversible hydration of carbon dioxide
BT246_RS25855	COG1271	oxidase subunit
BT246_RS25860	COG1294	oxidase, subunit
BT246_RS25875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT246_RS25900	COG1842	Phage shock protein A
BT246_RS25930	COG5002	protein histidine kinase activity
BT246_RS25935	COG0745	RESPONSE REGULATOR receiver
BT246_RS25960	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BT246_RS25965	COG1597	lipid kinase activity
BT246_RS26030	COG0586	Pfam SNARE associated Golgi protein
BT246_RS26040	COG0577	efflux transmembrane transporter activity
BT246_RS26045	COG1136	(ABC) transporter
BT246_RS26050	COG2207	Transcriptional regulator
BT246_RS26050	COG3708	Transcriptional regulator
BT246_RS26060	COG5658	integral membrane protein
BT246_RS26065	COG0640	Transcriptional regulator
BT246_RS26070	COG0745	RESPONSE REGULATOR receiver
BT246_RS26075	COG2205	protein histidine kinase activity
BT246_RS26080	COG0577	efflux transmembrane transporter activity
BT246_RS26085	COG0577	efflux transmembrane transporter activity
BT246_RS26090	COG1136	(ABC) transporter
BT246_RS26095	COG0577	efflux transmembrane transporter activity
BT246_RS26120	COG2188	Transcriptional regulator
BT246_RS26140	COG3964	amidohydrolase
BT246_RS26160	COG4948	Mandelate Racemase Muconate Lactonizing
BT246_RS26170	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BT246_RS26175	COG0596	Alpha beta hydrolase
BT246_RS26185	COG1169	isochorismate synthase
BT246_RS26190	COG1575	Belongs to the MenA family. Type 1 subfamily
BT246_RS26195	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BT246_RS26200	COG1278	Cold shock
BT246_RS26225	COG0058	SHG alpha-glucan phosphorylase activity
BT246_RS26235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BT246_RS26255	COG1404	Belongs to the peptidase S8 family
BT246_RS26390	COG1285	pathogenesis
BT246_RS26395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BT246_RS26410	COG2155	Conserved Protein
BT246_RS26415	COG1098	S1 RNA binding domain
BT246_RS26420	COG0436	Aminotransferase
BT246_RS26425	COG1522	sequence-specific DNA binding
BT246_RS26430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BT246_RS26435	COG2267	carboxylic ester hydrolase activity
BT246_RS26445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BT246_RS26470	COG5018	Exonuclease
BT246_RS26475	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BT246_RS26495	COG2050	protein possibly involved in aromatic compounds catabolism
BT246_RS26505	COG1268	BioY protein
BT246_RS26510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BT246_RS26515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BT246_RS26530	COG3584	3D domain protein
BT246_RS26545	COG1252	NADH dehydrogenase
BT246_RS26560	COG3708	Transcriptional regulator
BT246_RS26575	COG1683	Conserved Protein
BT246_RS26740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BT246_RS26770	COG0305	Participates in initiation and elongation during chromosome replication
BT246_RS26780	COG3723	Recombinational DNA repair protein, rece pathway
BT246_RS26785	COG5377	YqaJ viral recombinase family
BT246_RS26810	COG1396	sequence-specific DNA binding
BT246_RS26830	COG4122	O-methyltransferase activity
BT246_RS26845	COG0316	Belongs to the HesB IscA family
BT246_RS26860	COG1252	NADH dehydrogenase
BT246_RS26870	COG2274	protein secretion by the type I secretion system
BT246_RS26875	COG0390	transport system, permease component
BT246_RS26880	COG2824	Alkylphosphonate utilization operon protein PhnA
BT246_RS26905	COG4837	Protein of unknown function (DUF1462)
BT246_RS26910	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BT246_RS26920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BT246_RS26925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BT246_RS26945	COG1358	cellular component organization or biogenesis
BT246_RS26955	COG2249	NAD(P)H dehydrogenase (quinone) activity
BT246_RS26960	COG0647	UMP catabolic process
BT246_RS26970	COG2445	Protein of unknown function DUF86
BT246_RS26975	COG1494	fructose-1,6-bisphosphatase
BT246_RS26990	COG4470	Protein conserved in bacteria
BT246_RS27000	COG0789	Transcriptional regulator
BT246_RS27005	COG4377	Putative membrane peptidase family (DUF2324)
BT246_RS27030	COG0739	heme binding
BT246_RS27040	COG3377	Domain of unknown function (DUF1805)
BT246_RS27045	COG0737	Belongs to the 5'-nucleotidase family
BT246_RS27075	COG0457	Tetratricopeptide repeat
BT246_RS27080	COG1388	LysM domain
BT246_RS27080	COG3409	Peptidoglycan-binding domain 1 protein
BT246_RS27080	COG5632	N-Acetylmuramoyl-L-alanine amidase
BT246_RS27085	COG4824	toxin secretion phage lysis holin
BT246_RS27195	COG0582	viral genome integration into host DNA
BT246_RS27270	COG3646	Phage regulatory protein
BT246_RS27285	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BT246_RS27290	COG4974	Belongs to the 'phage' integrase family
BT246_RS27295	COG0719	Fe-S assembly protein
BT246_RS27300	COG0822	iron-sulfur transferase activity
BT246_RS27305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BT246_RS27310	COG0719	Fe-S assembly protein
BT246_RS27315	COG0396	ATPase activity
BT246_RS27320	COG1464	Belongs to the NlpA lipoprotein family
BT246_RS27325	COG1464	Belongs to the NlpA lipoprotein family
BT246_RS27330	COG2011	ABC-type metal ion transport system permease component
BT246_RS27345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BT246_RS27350	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BT246_RS27360	COG1393	Belongs to the ArsC family
BT246_RS27380	COG0039	L-malate dehydrogenase activity
BT246_RS27400	COG1309	transcriptional regulator
BT246_RS27405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT246_RS27410	COG1960	acyl-CoA dehydrogenase activity
BT246_RS27415	COG0183	Belongs to the thiolase family
BT246_RS27420	COG1250	3-hydroxyacyl-CoA dehydrogenase
BT246_RS27420	COG1024	Enoyl-CoA hydratase
BT246_RS27430	COG1686	Belongs to the peptidase S11 family
BT246_RS27445	COG0011	TIGRFAM Protein of
BT246_RS27450	COG0840	transmembrane signaling receptor activity
BT246_RS27465	COG2814	Major facilitator Superfamily
BT246_RS27470	COG0531	amino acid
BT246_RS27495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT246_RS27530	COG0586	Pfam SNARE associated Golgi protein
BT246_RS27540	COG1376	ErfK ybiS ycfS ynhG family protein
BT246_RS27545	COG0745	RESPONSE REGULATOR receiver
BT246_RS27550	COG5002	protein histidine kinase activity
BT246_RS27580	COG0840	transmembrane signaling receptor activity
BT246_RS27585	COG2151	metal-sulfur cluster biosynthetic enzyme
BT246_RS27590	COG3227	Zinc metalloprotease (Elastase)
BT246_RS27610	COG0586	Pfam SNARE associated Golgi protein
BT246_RS27615	COG0475	glutathione-regulated potassium exporter activity
BT246_RS27620	COG0490	domain, Protein
BT246_RS27625	COG1115	amino acid carrier protein
BT246_RS27630	COG0783	Belongs to the Dps family
BT246_RS27640	COG2318	DinB family
BT246_RS27650	COG1611	Belongs to the LOG family
BT246_RS27660	COG1528	Iron-storage protein
BT246_RS27670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT246_RS27675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT246_RS27680	COG1115	amino acid carrier protein
BT246_RS27685	COG1115	amino acid carrier protein
BT246_RS27690	COG2910	NAD(P)H-binding
BT246_RS27720	COG0656	L-ascorbic acid biosynthetic process
BT246_RS27725	COG2814	Major facilitator Superfamily
BT246_RS27730	COG1733	regulation of RNA biosynthetic process
BT246_RS27740	COG1252	NADH dehydrogenase
BT246_RS27745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BT246_RS27760	COG0840	transmembrane signaling receptor activity
BT246_RS27760	COG3290	protein histidine kinase activity
BT246_RS27790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT246_RS27805	COG1335	isochorismatase
BT246_RS27810	COG1522	sequence-specific DNA binding
BT246_RS27880	COG0557	exoribonuclease II activity
BT246_RS28055	COG0582	viral genome integration into host DNA
BT246_RS28070	COG3617	BRO family, N-terminal domain
BT246_RS28125	COG0582	viral genome integration into host DNA
BT246_RS28130	COG1647	Serine aminopeptidase, S33
BT246_RS28135	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BT246_RS28140	COG1346	cytolysis
BT246_RS28175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BT246_RS28190	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BT246_RS28200	COG1668	transmembrane transport
BT246_RS28205	COG4152	abc transporter atp-binding protein
BT246_RS28210	COG4585	Histidine kinase
BT246_RS28240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BT246_RS28255	COG2323	membrane
BT246_RS28265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BT246_RS28275	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BT246_RS28285	COG1051	belongs to the nudix hydrolase family
BT246_RS28295	COG0492	ferredoxin-NADP+ reductase activity
BT246_RS28300	COG0457	Tetratricopeptide repeat
BT246_RS28305	COG0110	maltose O-acetyltransferase activity
BT246_RS28325	COG1950	PFAM Membrane protein of
BT246_RS28335	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BT246_RS28355	COG0789	Transcriptional regulator
BT246_RS28375	COG0583	DNA-binding transcription factor activity
BT246_RS28390	COG0655	NAD(P)H dehydrogenase (quinone) activity
BT246_RS28395	COG0488	(ABC) transporter
BT246_RS28405	COG1132	(ABC) transporter
BT246_RS28410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BT246_RS28415	COG3409	Peptidoglycan-binding domain 1 protein
BT246_RS28415	COG0793	Belongs to the peptidase S41A family
BT246_RS28420	COG2177	Part of the ABC transporter FtsEX involved in
BT246_RS28425	COG2884	Cell division ATP-binding protein ftsE
BT246_RS28435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BT246_RS28445	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BT246_RS28450	COG1278	Cold shock
BT246_RS28455	COG1040	competence protein
BT246_RS28460	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BT246_RS28475	COG0577	efflux transmembrane transporter activity
BT246_RS28480	COG1136	(ABC) transporter
BT246_RS28510	COG4133	protoheme IX ABC transporter activity
BT246_RS28515	COG5632	N-Acetylmuramoyl-L-alanine amidase
BT246_RS28685	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BT246_RS28690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BT246_RS28695	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BT246_RS28700	COG1388	LysM domain
BT246_RS28700	COG0791	NLP P60 protein
BT246_RS28705	COG1733	regulation of RNA biosynthetic process
BT246_RS28710	COG1307	EDD domain protein, DegV family
BT246_RS28715	COG1739	Uncharacterized protein family UPF0029
BT246_RS28720	COG1316	TRANSCRIPTIONal
BT246_RS28725	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BT246_RS28730	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BT246_RS28735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BT246_RS28745	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BT246_RS28745	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BT246_RS28765	COG1486	melibiose metabolic process
BT246_RS28770	COG1447	Phosphotransferase system cellobiose-specific component IIA
BT246_RS28775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BT246_RS28810	COG1447	Phosphotransferase system cellobiose-specific component IIA
BT246_RS28820	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BT246_RS28825	COG1301	dicarboxylic acid transport
BT246_RS28840	COG1511	domain protein
BT246_RS28845	COG0583	DNA-binding transcription factor activity
BT246_RS28850	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BT246_RS28860	COG1271	oxidase subunit
BT246_RS28865	COG1294	oxidase, subunit
BT246_RS28870	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BT246_RS28890	COG1620	l-lactate permease
BT246_RS28900	COG2389	metal-binding protein
BT246_RS28910	COG1368	sulfuric ester hydrolase activity
BT246_RS28920	COG0791	NLP P60 protein
BT246_RS28920	COG1388	LysM domain
BT246_RS28925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT246_RS28935	COG1215	transferase activity, transferring glycosyl groups
BT246_RS28945	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BT246_RS28950	COG1388	LysM domain
BT246_RS28950	COG3584	3D domain protein
BT246_RS28975	COG4715	Zinc finger, swim domain protein
BT246_RS28980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BT246_RS29020	COG0577	efflux transmembrane transporter activity
BT246_RS29025	COG1136	(ABC) transporter
BT246_RS29060	COG5002	protein histidine kinase activity
BT246_RS29065	COG0745	RESPONSE REGULATOR receiver
BT246_RS29070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BT246_RS29095	COG1216	Glycosyl transferase, family 2
BT246_RS29100	COG0438	transferase activity, transferring glycosyl groups
BT246_RS29105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BT246_RS29120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BT246_RS29125	COG1086	Polysaccharide biosynthesis protein
BT246_RS29130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BT246_RS29135	COG4464	protein tyrosine phosphatase activity
BT246_RS29140	COG0489	protein tyrosine kinase activity
BT246_RS29145	COG3944	biosynthesis protein
BT246_RS29150	COG0489	protein tyrosine kinase activity
BT246_RS29165	COG1609	Transcriptional regulator
BT246_RS29175	COG0739	heme binding
BT246_RS29190	COG3279	Response regulator of the LytR AlgR family
BT246_RS29195	COG2385	sporulation resulting in formation of a cellular spore
BT246_RS29210	COG4836	Membrane
BT246_RS29215	COG1007	ATP synthesis coupled electron transport
BT246_RS29220	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BT246_RS29225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BT246_RS29235	COG0839	Belongs to the complex I subunit 6 family
BT246_RS29320	COG0356	it plays a direct role in the translocation of protons across the membrane
BT246_RS29355	COG0698	ribose 5-phosphate isomerase
BT246_RS29365	COG2190	(PTS) system
BT246_RS29370	COG2259	Doxx family
BT246_RS29375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BT246_RS29390	COG0009	L-threonylcarbamoyladenylate synthase
BT246_RS29425	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BT246_RS29430	COG1494	fructose-1,6-bisphosphatase
BT246_RS29450	COG4821	SIS domain
BT246_RS29460	COG3343	RNA polymerase activity
BT246_RS29470	COG1960	acyl-CoA dehydrogenase activity
BT246_RS29475	COG1960	acyl-CoA dehydrogenase activity
BT246_RS29480	COG1250	3-hydroxyacyl-CoA dehydrogenase
BT246_RS29485	COG0183	Belongs to the thiolase family
BT246_RS29490	COG2181	nitrate reductase activity
BT246_RS29490	COG0247	lactate metabolic process
BT246_RS29495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BT246_RS29515	COG5001	Diguanylate cyclase
BT246_RS29515	COG3300	MHYT domain
BT246_RS29530	COG3227	Zinc metalloprotease (Elastase)
BT246_RS29535	COG2197	response regulator
BT246_RS29540	COG4585	Histidine kinase
BT246_RS29545	COG0842	Transport permease protein
BT246_RS29550	COG1131	(ABC) transporter
BT246_RS29555	COG0024	Methionine aminopeptidase
BT246_RS29565	COG2234	aminopeptidase activity
BT246_RS29585	COG4506	Protein conserved in bacteria
BT246_RS29590	COG1619	proteins homologs of microcin C7 resistance protein MccF
BT246_RS29615	COG2814	Major facilitator Superfamily
BT246_RS29620	COG0789	Transcriptional regulator
BT246_RS29625	COG0584	glycerophosphoryl diester phosphodiesterase
BT246_RS29630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BT246_RS29640	COG1994	Peptidase M50
BT246_RS29650	COG1078	dGTPase activity
BT246_RS29655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT246_RS29660	COG1120	ATPase activity
BT246_RS29665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT246_RS29670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT246_RS29690	COG0280	phosphate acetyltransferase
BT246_RS29705	COG3773	Cell wall hydrolase
BT246_RS29715	COG2363	Small membrane protein
BT246_RS29725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BT246_RS29730	COG2233	PERMEase
BT246_RS29735	COG0561	phosphatase activity
BT246_RS29740	COG2814	Major facilitator Superfamily
BT246_RS29750	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BT246_RS29755	COG1131	(ABC) transporter
BT246_RS29760	COG2755	lipolytic protein G-D-S-L family
BT246_RS29765	COG1609	Transcriptional regulator
BT246_RS29785	COG0460	homoserine dehydrogenase
BT246_RS29795	COG2873	o-acetylhomoserine
BT246_RS29805	COG1011	Hydrolase
BT246_RS29810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BT246_RS29820	COG2197	response regulator
BT246_RS29825	COG4585	Histidine kinase
BT246_RS29825	COG2203	Gaf domain
BT246_RS29830	COG0351	phosphomethylpyrimidine kinase
BT246_RS29835	COG3706	GGDEF domain
BT246_RS29840	COG2879	small protein
BT246_RS29845	COG1966	Carbon starvation protein
BT246_RS29850	COG3279	Response regulator of the LytR AlgR family
BT246_RS29855	COG0477	Major facilitator Superfamily
BT246_RS29865	COG0438	transferase activity, transferring glycosyl groups
BT246_RS29880	COG0840	transmembrane signaling receptor activity
BT246_RS29890	COG1607	acyl-coa hydrolase
BT246_RS29895	COG1216	Glycosyl transferase, family 2
BT246_RS29910	COG1216	Glycosyl transferase, family 2
BT246_RS29925	COG0463	Glycosyl transferase, family 2
BT246_RS29935	COG1309	transcriptional regulator
BT246_RS29940	COG0488	(ABC) transporter
BT246_RS29945	COG1309	transcriptional regulator
BT246_RS29950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BT246_RS29955	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BT246_RS29955	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BT246_RS29960	COG0628	permease
BT246_RS29980	COG1346	cytolysis
BT246_RS30000	COG3547	Transposase (IS116 IS110 IS902 family)
BT246_RS30005	COG3275	phosphorelay sensor kinase activity
BT246_RS30010	COG2814	Major facilitator Superfamily
BT246_RS30025	COG2814	Major facilitator Superfamily
BT246_RS30030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BT246_RS30035	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BT246_RS30060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BT246_RS30065	COG1272	protein, Hemolysin III
BT246_RS30085	COG1164	Oligoendopeptidase f
BT246_RS30110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BT246_RS30115	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BT246_RS30120	COG4853	Protein conserved in bacteria
BT246_RS30130	COG5002	protein histidine kinase activity
BT246_RS30135	COG0745	RESPONSE REGULATOR receiver
BT246_RS30165	COG0305	Participates in initiation and elongation during chromosome replication
BT246_RS30175	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BT246_RS30180	COG4241	membrane
BT246_RS30190	COG0629	single-stranded DNA binding
BT246_RS30200	COG0012	GTP binding
BT246_RS30205	COG4481	Protein conserved in bacteria
BT246_RS30210	COG0668	transmembrane transport
BT246_RS30220	COG1475	DNA binding
BT246_RS30225	COG1192	Involved in chromosome partitioning
BT246_RS30250	COG1847	R3H domain protein
BT246_RS30255	COG0706	membrane insertase activity
BT246_RS30265	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BT246_RS30320	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BT246_RS30520	COG0084	hydrolase, TatD family'
BT246_RS30640	COG2208	phosphoserine phosphatase activity
BT246_RS30825	COG0542	response to heat
BT246_RS31070	COG0726	polysaccharide deacetylase
BT246_RS31360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BT246_RS31425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BT246_RS31455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BT246_RS31750	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BT246_RS31895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BT246_RS32235	COG0512	Glutamine amidotransferase of anthranilate synthase
BT246_RS32365	COG0542	response to heat
BT246_RS32370	COG0542	response to heat
BT246_RS32540	COG0516	GMP reductase activity
BT246_RS32540	COG0517	IMP dehydrogenase activity
BT246_RS32915	COG0542	response to heat
BT246_RS33480	COG0542	response to heat
BT246_RS33590	COG0187	DNA topoisomerase II activity
BT246_RS33960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BT246_RS34295	COG0084	hydrolase, TatD family'
BT246_RS34425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BT246_RS34750	COG0517	IMP dehydrogenase activity
BT246_RS34750	COG0516	GMP reductase activity