locus-tag	class	description
Bt4C1_RS00020	COG0516	GMP reductase activity
Bt4C1_RS00020	COG0517	IMP dehydrogenase activity
Bt4C1_RS00025	COG1686	Belongs to the peptidase S11 family
Bt4C1_RS00055	COG1428	Deoxynucleoside kinase
Bt4C1_RS00060	COG1428	Deoxynucleoside kinase
Bt4C1_RS00065	COG1335	isochorismatase
Bt4C1_RS00070	COG0590	tRNA wobble adenosine to inosine editing
Bt4C1_RS00080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Bt4C1_RS00135	COG1982	Orn Lys Arg decarboxylase major
Bt4C1_RS00145	COG0470	DNA polymerase III
Bt4C1_RS00150	COG1774	PSP1 C-terminal conserved region
Bt4C1_RS00160	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Bt4C1_RS00170	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Bt4C1_RS00175	COG2002	toxin-antitoxin pair type II binding
Bt4C1_RS00185	COG0084	hydrolase, TatD family'
Bt4C1_RS00205	COG4466	Protein conserved in bacteria
Bt4C1_RS00220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Bt4C1_RS00225	COG0251	oxidation-reduction process
Bt4C1_RS00255	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Bt4C1_RS00260	COG2002	toxin-antitoxin pair type II binding
Bt4C1_RS00265	COG2244	polysaccharide biosynthetic process
Bt4C1_RS00270	COG3956	TIGRFAM MazG family protein
Bt4C1_RS00275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Bt4C1_RS00295	COG1098	S1 RNA binding domain
Bt4C1_RS00310	COG2208	phosphoserine phosphatase activity
Bt4C1_RS00320	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Bt4C1_RS00325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Bt4C1_RS00340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Bt4C1_RS00345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Bt4C1_RS00350	COG0512	Glutamine amidotransferase of anthranilate synthase
Bt4C1_RS00355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Bt4C1_RS00360	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Bt4C1_RS00365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Bt4C1_RS00370	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Bt4C1_RS00375	COG1396	sequence-specific DNA binding
Bt4C1_RS00380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Bt4C1_RS00410	COG3880	PFAM UvrB UvrC protein
Bt4C1_RS00420	COG0542	response to heat
Bt4C1_RS00425	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Bt4C1_RS00435	COG4956	integral membrane protein (PIN domain superfamily)
Bt4C1_RS00455	COG1045	serine acetyltransferase
Bt4C1_RS00470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Bt4C1_RS00475	COG3688	RNA-binding protein containing a PIN domain
Bt4C1_RS00485	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Bt4C1_RS00490	COG0250	Participates in transcription elongation, termination and antitermination
Bt4C1_RS00495	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Bt4C1_RS00515	COG2813	Specifically methylates the guanine in position
Bt4C1_RS00525	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Bt4C1_RS00530	COG1358	cellular component organization or biogenesis
Bt4C1_RS00535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Bt4C1_RS00555	COG0051	transcription antitermination factor activity, RNA binding
Bt4C1_RS00560	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Bt4C1_RS00600	COG0255	Belongs to the universal ribosomal protein uL29 family
Bt4C1_RS00660	COG0201	protein transport
Bt4C1_RS00670	COG0024	Methionine aminopeptidase
Bt4C1_RS00680	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Bt4C1_RS00715	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Bt4C1_RS00740	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_RS00745	COG0489	protein tyrosine kinase activity
Bt4C1_RS00755	COG2194	sulfuric ester hydrolase activity
Bt4C1_RS00760	COG0726	polysaccharide deacetylase
Bt4C1_RS00840	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Bt4C1_RS00845	COG4856	YbbR-like protein
Bt4C1_RS00880	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS00885	COG2011	ABC-type metal ion transport system permease component
Bt4C1_RS00890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Bt4C1_RS00895	COG1464	Belongs to the NlpA lipoprotein family
Bt4C1_RS00900	COG0604	alcohol dehydrogenase
Bt4C1_RS00910	COG0277	FAD linked oxidase domain protein
Bt4C1_RS00915	COG2271	Major facilitator Superfamily
Bt4C1_RS00925	COG2814	Major facilitator Superfamily
Bt4C1_RS00945	COG0601	transmembrane transport
Bt4C1_RS00950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bt4C1_RS00955	COG0444	Belongs to the ABC transporter superfamily
Bt4C1_RS00960	COG4608	Belongs to the ABC transporter superfamily
Bt4C1_RS00965	COG4166	transmembrane transport
Bt4C1_RS00980	COG4166	transmembrane transport
Bt4C1_RS00985	COG4166	transmembrane transport
Bt4C1_RS00990	COG0656	L-ascorbic acid biosynthetic process
Bt4C1_RS01005	COG4149	molybdate abc transporter
Bt4C1_RS01010	COG0725	ABC transporter, periplasmic molybdate-binding protein
Bt4C1_RS01015	COG1910	domain protein
Bt4C1_RS01025	COG0697	spore germination
Bt4C1_RS01035	COG0204	Acyl-transferase
Bt4C1_RS01040	COG1609	Transcriptional regulator
Bt4C1_RS01050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_RS01070	COG5298	Protein conserved in bacteria
Bt4C1_RS01090	COG0488	(ABC) transporter
Bt4C1_RS01100	COG0747	negative chemotaxis
Bt4C1_RS01105	COG0601	transmembrane transport
Bt4C1_RS01110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bt4C1_RS01115	COG0444	Belongs to the ABC transporter superfamily
Bt4C1_RS01120	COG4608	Belongs to the ABC transporter superfamily
Bt4C1_RS01125	COG0561	phosphatase activity
Bt4C1_RS01160	COG3185	4-Hydroxyphenylpyruvate dioxygenase
Bt4C1_RS01165	COG0179	Fumarylacetoacetate (FAA) hydrolase
Bt4C1_RS01175	COG0531	amino acid
Bt4C1_RS01180	COG2814	Major facilitator Superfamily
Bt4C1_RS01190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Bt4C1_RS01200	COG4294	response to UV
Bt4C1_RS01205	COG0705	Rhomboid family
Bt4C1_RS01215	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Bt4C1_RS01220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Bt4C1_RS01225	COG0864	Transcriptional regulator
Bt4C1_RS01230	COG2337	Toxic component of a toxin-antitoxin (TA) module
Bt4C1_RS01235	COG2183	response to ionizing radiation
Bt4C1_RS01330	COG0802	atpase or kinase
Bt4C1_RS01335	COG1214	PFAM Peptidase M22, glycoprotease
Bt4C1_RS01340	COG0456	acetyltransferase
Bt4C1_RS01350	COG0488	(ABC) transporter
Bt4C1_RS01365	COG1266	CAAX protease self-immunity
Bt4C1_RS01385	COG2252	PERMEase
Bt4C1_RS01395	COG5002	protein histidine kinase activity
Bt4C1_RS01420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Bt4C1_RS01460	COG2205	protein histidine kinase activity
Bt4C1_RS01465	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS01485	COG0697	spore germination
Bt4C1_RS01510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Bt4C1_RS01515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Bt4C1_RS01520	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Bt4C1_RS01530	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Bt4C1_RS01545	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Bt4C1_RS01555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Bt4C1_RS01565	COG0151	Belongs to the GarS family
Bt4C1_RS01590	COG0210	DNA helicase
Bt4C1_RS01600	COG4851	CamS sex pheromone cAM373 precursor
Bt4C1_RS01615	COG1335	isochorismatase
Bt4C1_RS01625	COG2011	ABC-type metal ion transport system permease component
Bt4C1_RS01630	COG1464	Belongs to the NlpA lipoprotein family
Bt4C1_RS01640	COG0003	Pfam Anion-transporting ATPase
Bt4C1_RS01645	COG1846	Transcriptional regulator
Bt4C1_RS01650	COG4682	membrane
Bt4C1_RS01670	COG1597	lipid kinase activity
Bt4C1_RS01675	COG0546	phosphoglycolate phosphatase activity
Bt4C1_RS01680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Bt4C1_RS01690	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_RS01695	COG2076	Multidrug Resistance protein
Bt4C1_RS01705	COG2309	aminopeptidase activity
Bt4C1_RS01720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_RS01730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Bt4C1_RS01735	COG4807	Protein conserved in bacteria
Bt4C1_RS01760	COG1757	Na H antiporter
Bt4C1_RS01765	COG1473	amidohydrolase
Bt4C1_RS01780	COG0450	alkyl hydroperoxide reductase
Bt4C1_RS01790	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Bt4C1_RS01800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_RS01805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_RS01810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bt4C1_RS01825	COG0166	Belongs to the GPI family
Bt4C1_RS01850	COG5002	protein histidine kinase activity
Bt4C1_RS01870	COG3541	Predicted nucleotidyltransferase
Bt4C1_RS01875	COG2814	Major facilitator Superfamily
Bt4C1_RS01880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bt4C1_RS01880	COG0723	plastoquinol--plastocyanin reductase activity
Bt4C1_RS01890	COG0765	amino acid transport
Bt4C1_RS01895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bt4C1_RS01900	COG1126	abc transporter atp-binding protein
Bt4C1_RS01905	COG0840	transmembrane signaling receptor activity
Bt4C1_RS01930	COG0549	Belongs to the carbamate kinase family
Bt4C1_RS01935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bt4C1_RS01945	COG0277	FAD linked oxidase domain protein
Bt4C1_RS01950	COG0366	Alpha amylase catalytic
Bt4C1_RS01955	COG2190	(PTS) system
Bt4C1_RS01955	COG1263	PTS System
Bt4C1_RS01955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bt4C1_RS01985	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Bt4C1_RS02005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bt4C1_RS02010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bt4C1_RS02015	COG1116	anion transmembrane transporter activity
Bt4C1_RS02060	COG2270	Major facilitator Superfamily
Bt4C1_RS02090	COG2310	stress, protein
Bt4C1_RS02095	COG2310	stress, protein
Bt4C1_RS02100	COG2310	stress, protein
Bt4C1_RS02105	COG0861	Integral membrane protein TerC family
Bt4C1_RS02115	COG3853	Toxic anion resistance protein (TelA)
Bt4C1_RS02130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Bt4C1_RS02140	COG1295	ribonuclease BN
Bt4C1_RS02145	COG2217	Heavy metal translocating P-type atpase
Bt4C1_RS02150	COG0697	spore germination
Bt4C1_RS02160	COG0681	Belongs to the peptidase S26 family
Bt4C1_RS02170	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_RS02185	COG3871	stress protein (general stress protein 26)
Bt4C1_RS02190	COG0387	Pfam Sodium calcium exchanger
Bt4C1_RS02200	COG0535	radical SAM domain protein
Bt4C1_RS02220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Bt4C1_RS02225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Bt4C1_RS02245	COG3829	transcription factor binding
Bt4C1_RS02255	COG0833	amino acid
Bt4C1_RS02260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Bt4C1_RS02285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bt4C1_RS02285	COG1263	PTS System
Bt4C1_RS02290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Bt4C1_RS02305	COG0463	Glycosyl transferase, family 2
Bt4C1_RS02315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Bt4C1_RS02315	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Bt4C1_RS02320	COG0463	Glycosyl transferase, family 2
Bt4C1_RS02330	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Bt4C1_RS02350	COG1228	amidohydrolase
Bt4C1_RS02355	COG1090	epimerase
Bt4C1_RS02385	COG1988	membrane-bound metal-dependent
Bt4C1_RS02390	COG1194	a g-specific adenine glycosylase
Bt4C1_RS02415	COG1132	(ABC) transporter
Bt4C1_RS02420	COG4129	membrane
Bt4C1_RS02425	COG0070	glutamate synthase
Bt4C1_RS02425	COG0069	glutamate synthase activity
Bt4C1_RS02425	COG0067	glutamate synthase
Bt4C1_RS02435	COG4555	ABC transporter
Bt4C1_RS02455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Bt4C1_RS02460	COG0735	belongs to the Fur family
Bt4C1_RS02565	COG4974	Belongs to the 'phage' integrase family
Bt4C1_RS02590	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Bt4C1_RS02655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Bt4C1_RS02680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Bt4C1_RS02690	COG2766	serine protein kinase
Bt4C1_RS02705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bt4C1_RS02715	COG1585	Membrane protein implicated in regulation of membrane protease activity
Bt4C1_RS02720	COG2268	Band 7 protein
Bt4C1_RS02730	COG3290	protein histidine kinase activity
Bt4C1_RS02735	COG4565	transcriptional regulatory protein
Bt4C1_RS02740	COG2851	Citrate transporter
Bt4C1_RS02765	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
Bt4C1_RS02770	COG3842	ATPase activity
Bt4C1_RS02775	COG1175	transmembrane transport
Bt4C1_RS02780	COG0395	ABC-type sugar transport system, permease component
Bt4C1_RS02790	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Bt4C1_RS02795	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS02800	COG5002	protein histidine kinase activity
Bt4C1_RS02810	COG4990	cell redox homeostasis
Bt4C1_RS02820	COG3290	protein histidine kinase activity
Bt4C1_RS02825	COG4565	transcriptional regulatory protein
Bt4C1_RS02830	COG3493	citrate carrier protein
Bt4C1_RS02835	COG0281	malic enzyme
Bt4C1_RS02850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_RS02860	COG5002	protein histidine kinase activity
Bt4C1_RS02885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Bt4C1_RS02890	COG3383	formate dehydrogenase (NAD+) activity
Bt4C1_RS02895	COG2427	Protein of unknown function (DUF1641)
Bt4C1_RS02910	COG0531	amino acid
Bt4C1_RS02915	COG0640	Transcriptional regulator
Bt4C1_RS02920	COG2217	Heavy metal translocating P-type atpase
Bt4C1_RS02925	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Bt4C1_RS02935	COG3227	Zinc metalloprotease (Elastase)
Bt4C1_RS02955	COG2720	vancomycin resistance protein
Bt4C1_RS02960	COG1316	TRANSCRIPTIONal
Bt4C1_RS02965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_RS02970	COG0346	lactoylglutathione lyase activity
Bt4C1_RS02975	COG1253	flavin adenine dinucleotide binding
Bt4C1_RS02980	COG1027	Aspartate ammonia-lyase
Bt4C1_RS02985	COG1620	l-lactate permease
Bt4C1_RS03000	COG3104	oligopeptide transport
Bt4C1_RS03005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bt4C1_RS03010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_RS03015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_RS03030	COG0156	8-amino-7-oxononanoate synthase activity
Bt4C1_RS03035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Bt4C1_RS03045	COG4548	von Willebrand factor, type A
Bt4C1_RS03050	COG0714	Associated with various cellular activities
Bt4C1_RS03070	COG0531	amino acid
Bt4C1_RS03075	COG2188	Transcriptional regulator
Bt4C1_RS03080	COG1263	PTS System
Bt4C1_RS03080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bt4C1_RS03085	COG0366	Alpha amylase catalytic
Bt4C1_RS03100	COG0697	spore germination
Bt4C1_RS03110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Bt4C1_RS03115	COG1115	amino acid carrier protein
Bt4C1_RS03125	COG1126	abc transporter atp-binding protein
Bt4C1_RS03130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bt4C1_RS03135	COG0765	amino acid transport
Bt4C1_RS03140	COG0765	amino acid transport
Bt4C1_RS03145	COG0833	amino acid
Bt4C1_RS03160	COG1595	DNA-templated transcription, initiation
Bt4C1_RS03170	COG2378	regulation of single-species biofilm formation
Bt4C1_RS03175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Bt4C1_RS03180	COG5002	protein histidine kinase activity
Bt4C1_RS03205	COG0659	secondary active sulfate transmembrane transporter activity
Bt4C1_RS03220	COG2271	Major facilitator Superfamily
Bt4C1_RS03225	COG1846	Transcriptional regulator
Bt4C1_RS03230	COG0477	Major facilitator Superfamily
Bt4C1_RS03235	COG1609	Transcriptional regulator
Bt4C1_RS03240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Bt4C1_RS03255	COG4974	Belongs to the 'phage' integrase family
Bt4C1_RS03350	COG3331	DNA recombination
Bt4C1_RS03490	COG4824	toxin secretion phage lysis holin
Bt4C1_RS03525	COG1172	Belongs to the binding-protein-dependent transport system permease family
Bt4C1_RS03530	COG1879	ABC-type sugar transport system periplasmic component
Bt4C1_RS03560	COG1063	alcohol dehydrogenase
Bt4C1_RS03610	COG0840	transmembrane signaling receptor activity
Bt4C1_RS03615	COG3584	3D domain protein
Bt4C1_RS03615	COG1388	LysM domain
Bt4C1_RS03620	COG1476	TRANSCRIPTIONal
Bt4C1_RS03640	COG3104	oligopeptide transport
Bt4C1_RS03645	COG1114	Component of the transport system for branched-chain amino acids
Bt4C1_RS03660	COG1113	amino acid transport
Bt4C1_RS03665	COG2252	PERMEase
Bt4C1_RS03680	COG2153	protein acetylation
Bt4C1_RS03690	COG0475	glutathione-regulated potassium exporter activity
Bt4C1_RS03690	COG0569	domain protein
Bt4C1_RS03705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Bt4C1_RS03715	COG0833	amino acid
Bt4C1_RS03720	COG4990	cell redox homeostasis
Bt4C1_RS03735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Bt4C1_RS03740	COG0697	spore germination
Bt4C1_RS03745	COG0531	amino acid
Bt4C1_RS03755	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Bt4C1_RS03760	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Bt4C1_RS03765	COG1918	ferrous iron import across plasma membrane
Bt4C1_RS03765	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Bt4C1_RS03770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Bt4C1_RS03775	COG0573	inorganic phosphate transmembrane transporter activity
Bt4C1_RS03780	COG0581	inorganic phosphate transmembrane transporter activity
Bt4C1_RS03790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Bt4C1_RS03905	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Bt4C1_RS03925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Bt4C1_RS03930	COG1116	anion transmembrane transporter activity
Bt4C1_RS03935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bt4C1_RS03940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bt4C1_RS03945	COG0352	thiamine-phosphate diphosphorylase activity
Bt4C1_RS03950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bt4C1_RS03955	COG2104	thiamine diphosphate biosynthetic process
Bt4C1_RS03965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bt4C1_RS03970	COG0351	phosphomethylpyrimidine kinase
Bt4C1_RS04010	COG2205	protein histidine kinase activity
Bt4C1_RS04015	COG2814	Major facilitator Superfamily
Bt4C1_RS04020	COG1846	Transcriptional regulator
Bt4C1_RS04035	COG2252	PERMEase
Bt4C1_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS04100	COG0778	Nitroreductase
Bt4C1_RS04105	COG2719	SpoVR family
Bt4C1_RS04115	COG1937	Protein conserved in bacteria
Bt4C1_RS04120	COG0425	Belongs to the sulfur carrier protein TusA family
Bt4C1_RS04120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bt4C1_RS04125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bt4C1_RS04125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_RS04130	COG0425	Belongs to the sulfur carrier protein TusA family
Bt4C1_RS04135	COG0425	Belongs to the sulfur carrier protein TusA family
Bt4C1_RS04135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bt4C1_RS04145	COG2210	Belongs to the sulfur carrier protein TusA family
Bt4C1_RS04150	COG0730	response to heat
Bt4C1_RS04160	COG1316	TRANSCRIPTIONal
Bt4C1_RS04165	COG0604	alcohol dehydrogenase
Bt4C1_RS04170	COG1283	sodium-dependent phosphate transmembrane transporter activity
Bt4C1_RS04185	COG3711	transcriptional antiterminator
Bt4C1_RS04185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bt4C1_RS04190	COG1447	Phosphotransferase system cellobiose-specific component IIA
Bt4C1_RS04195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bt4C1_RS04220	COG3584	3D domain protein
Bt4C1_RS04220	COG1388	LysM domain
Bt4C1_RS04225	COG0577	efflux transmembrane transporter activity
Bt4C1_RS04230	COG1136	(ABC) transporter
Bt4C1_RS04240	COG5522	Integral membrane protein (intg_mem_TP0381)
Bt4C1_RS04255	COG1114	Component of the transport system for branched-chain amino acids
Bt4C1_RS04260	COG3546	catalase activity
Bt4C1_RS04295	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_RS04325	COG0531	amino acid
Bt4C1_RS04330	COG0475	glutathione-regulated potassium exporter activity
Bt4C1_RS04340	COG1737	Transcriptional regulator
Bt4C1_RS04350	COG1263	PTS System
Bt4C1_RS04350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bt4C1_RS04360	COG2259	Doxx family
Bt4C1_RS04380	COG1522	sequence-specific DNA binding
Bt4C1_RS04390	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS04395	COG0789	Transcriptional regulator
Bt4C1_RS04410	COG1309	transcriptional regulator
Bt4C1_RS04415	COG2814	Major facilitator Superfamily
Bt4C1_RS04425	COG2801	Transposase and inactivated derivatives
Bt4C1_RS04430	COG1733	regulation of RNA biosynthetic process
Bt4C1_RS04450	COG0693	protein deglycase activity
Bt4C1_RS04455	COG0693	protein deglycase activity
Bt4C1_RS04455	COG0753	catalase activity
Bt4C1_RS04465	COG0531	amino acid
Bt4C1_RS04470	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_RS04475	COG1132	(ABC) transporter
Bt4C1_RS04480	COG1132	(ABC) transporter
Bt4C1_RS04485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bt4C1_RS04490	COG0765	amino acid transport
Bt4C1_RS04495	COG1126	abc transporter atp-binding protein
Bt4C1_RS04510	COG0189	ligase activity
Bt4C1_RS04540	COG0028	Belongs to the TPP enzyme family
Bt4C1_RS04545	COG3527	Alpha-acetolactate decarboxylase
Bt4C1_RS04560	COG0561	phosphatase activity
Bt4C1_RS04565	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_RS04565	COG3409	Peptidoglycan-binding domain 1 protein
Bt4C1_RS04570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Bt4C1_RS04585	COG0659	secondary active sulfate transmembrane transporter activity
Bt4C1_RS04590	COG2244	polysaccharide biosynthetic process
Bt4C1_RS04610	COG1024	Enoyl-CoA hydratase
Bt4C1_RS04630	COG1363	Peptidase, m42
Bt4C1_RS04670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bt4C1_RS04675	COG0444	Belongs to the ABC transporter superfamily
Bt4C1_RS04680	COG4608	Belongs to the ABC transporter superfamily
Bt4C1_RS04690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_RS04710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Bt4C1_RS04725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bt4C1_RS04730	COG2814	Major facilitator Superfamily
Bt4C1_RS04760	COG2801	Transposase and inactivated derivatives
Bt4C1_RS04830	COG0582	viral genome integration into host DNA
Bt4C1_RS04835	COG0477	Major facilitator Superfamily
Bt4C1_RS04840	COG3290	protein histidine kinase activity
Bt4C1_RS04845	COG4565	transcriptional regulatory protein
Bt4C1_RS04850	COG3181	Tripartite tricarboxylate transporter family receptor
Bt4C1_RS04885	COG1401	restriction endodeoxyribonuclease activity
Bt4C1_RS04905	COG0305	Participates in initiation and elongation during chromosome replication
Bt4C1_RS04935	COG0477	Major facilitator Superfamily
Bt4C1_RS04950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_RS04975	COG1073	alpha beta
Bt4C1_RS05025	COG1183	phosphatidylcholine synthase activity
Bt4C1_RS05035	COG2814	Major facilitator Superfamily
Bt4C1_RS05040	COG0640	Transcriptional regulator
Bt4C1_RS05050	COG2376	Dihydroxyacetone kinase
Bt4C1_RS05060	COG2376	Dihydroxyacetone kinase
Bt4C1_RS05070	COG1959	2 iron, 2 sulfur cluster binding
Bt4C1_RS05095	COG2373	Large extracellular alpha-helical protein
Bt4C1_RS05135	COG3237	CsbD-like
Bt4C1_RS05160	COG1191	sigma factor activity
Bt4C1_RS05170	COG2208	phosphoserine phosphatase activity
Bt4C1_RS05175	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Bt4C1_RS05215	COG3344	reverse transcriptase
Bt4C1_RS05225	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
Bt4C1_RS05245	COG0420	3'-5' exonuclease activity
Bt4C1_RS05250	COG4717	serine-type aminopeptidase activity
Bt4C1_RS05260	COG4974	Belongs to the 'phage' integrase family
Bt4C1_RS05290	COG3646	Phage regulatory protein
Bt4C1_RS05360	COG3331	DNA recombination
Bt4C1_RS05550	COG1280	lysine exporter protein (LysE YggA)
Bt4C1_RS05555	COG0346	lactoylglutathione lyase activity
Bt4C1_RS05560	COG0346	lactoylglutathione lyase activity
Bt4C1_RS05565	COG0457	Tetratricopeptide repeat
Bt4C1_RS05575	COG2267	carboxylic ester hydrolase activity
Bt4C1_RS05590	COG2140	Oxalate decarboxylase
Bt4C1_RS05595	COG3620	sequence-specific DNA binding
Bt4C1_RS05600	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
Bt4C1_RS05605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Bt4C1_RS05615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Bt4C1_RS05620	COG1695	Transcriptional regulator
Bt4C1_RS05640	COG0772	Belongs to the SEDS family
Bt4C1_RS05645	COG3973	AAA domain
Bt4C1_RS05675	COG4980	gas vesicle protein
Bt4C1_RS05680	COG0537	adenosine 5'-monophosphoramidase activity
Bt4C1_RS05685	COG1131	(ABC) transporter
Bt4C1_RS05690	COG4473	ABC transporter
Bt4C1_RS05700	COG1309	transcriptional regulator
Bt4C1_RS05710	COG3402	PFAM membrane-flanked domain
Bt4C1_RS05715	COG3428	Bacterial PH domain
Bt4C1_RS05750	COG0697	spore germination
Bt4C1_RS05755	COG3402	PFAM membrane-flanked domain
Bt4C1_RS05760	COG3428	Bacterial PH domain
Bt4C1_RS05765	COG2329	Antibiotic biosynthesis monooxygenase
Bt4C1_RS05770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bt4C1_RS05785	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Bt4C1_RS05810	COG1309	transcriptional regulator
Bt4C1_RS05815	COG1511	domain protein
Bt4C1_RS05840	COG1609	Transcriptional regulator
Bt4C1_RS05850	COG1234	tRNA 3'-trailer cleavage
Bt4C1_RS05855	COG0095	Lipoate-protein ligase
Bt4C1_RS05865	COG0318	PFAM AMP-dependent synthetase and ligase
Bt4C1_RS05890	COG1309	transcriptional regulator
Bt4C1_RS05895	COG1073	alpha beta
Bt4C1_RS05900	COG1408	metallophosphoesterase
Bt4C1_RS05905	COG1078	dGTPase activity
Bt4C1_RS05915	COG1595	DNA-templated transcription, initiation
Bt4C1_RS05920	COG2207	Transcriptional regulator
Bt4C1_RS05920	COG3708	Transcriptional regulator
Bt4C1_RS05930	COG2205	protein histidine kinase activity
Bt4C1_RS05950	COG0501	Belongs to the peptidase M48B family
Bt4C1_RS05955	COG0840	transmembrane signaling receptor activity
Bt4C1_RS05965	COG3693	PFAM glycoside hydrolase, family 10
Bt4C1_RS05975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Bt4C1_RS05980	COG2224	Isocitrate lyase
Bt4C1_RS05995	COG1278	Cold shock
Bt4C1_RS06010	COG4903	ComK protein
Bt4C1_RS06015	COG0398	Pfam SNARE associated Golgi protein
Bt4C1_RS06075	COG0179	Fumarylacetoacetate (FAA) hydrolase
Bt4C1_RS06100	COG0367	asparagine synthase
Bt4C1_RS06110	COG0753	catalase activity
Bt4C1_RS06115	COG0004	ammonium transporteR
Bt4C1_RS06135	COG2996	Protein conserved in bacteria
Bt4C1_RS06145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_RS06160	COG0561	phosphatase activity
Bt4C1_RS06180	COG2267	carboxylic ester hydrolase activity
Bt4C1_RS06195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Bt4C1_RS06200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Bt4C1_RS06205	COG5504	Zn-dependent protease
Bt4C1_RS06220	COG0180	Tryptophanyl-tRNA synthetase
Bt4C1_RS06230	COG4166	transmembrane transport
Bt4C1_RS06235	COG0601	transmembrane transport
Bt4C1_RS06240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bt4C1_RS06245	COG0444	Belongs to the ABC transporter superfamily
Bt4C1_RS06250	COG4608	Belongs to the ABC transporter superfamily
Bt4C1_RS06255	COG0534	Mate efflux family protein
Bt4C1_RS06260	COG4166	transmembrane transport
Bt4C1_RS06275	COG0861	Integral membrane protein TerC family
Bt4C1_RS06285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bt4C1_RS06295	COG1164	Oligoendopeptidase f
Bt4C1_RS06305	COG2346	COG2346, Truncated hemoglobins
Bt4C1_RS06310	COG4116	CYTH
Bt4C1_RS06320	COG2357	RelA SpoT domain protein
Bt4C1_RS06330	COG0564	pseudouridine synthase activity
Bt4C1_RS06345	COG0772	Belongs to the SEDS family
Bt4C1_RS06350	COG1216	Glycosyl transferase, family 2
Bt4C1_RS06370	COG0457	Tetratricopeptide repeat
Bt4C1_RS06370	COG0463	Glycosyl transferase, family 2
Bt4C1_RS06390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Bt4C1_RS06405	COG1091	dTDP-4-dehydrorhamnose reductase activity
Bt4C1_RS06450	COG2153	protein acetylation
Bt4C1_RS06460	COG2382	esterase
Bt4C1_RS06475	COG5492	domain, Protein
Bt4C1_RS06480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Bt4C1_RS06490	COG0512	Glutamine amidotransferase of anthranilate synthase
Bt4C1_RS06490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Bt4C1_RS06525	COG1620	l-lactate permease
Bt4C1_RS06535	COG5634	Uncharacterized conserved protein (DUF2278)
Bt4C1_RS06590	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bt4C1_RS06600	COG1476	TRANSCRIPTIONal
Bt4C1_RS06625	COG4152	abc transporter atp-binding protein
Bt4C1_RS06630	COG1668	transmembrane transport
Bt4C1_RS06650	COG2226	methyltransferase
Bt4C1_RS06660	COG1686	Belongs to the peptidase S11 family
Bt4C1_RS06665	COG0681	Belongs to the peptidase S26 family
Bt4C1_RS06700	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_RS06710	COG1176	ABC-type spermidine putrescine transport system, permease component I
Bt4C1_RS06715	COG1177	transmembrane transport
Bt4C1_RS06725	COG0671	phosphoesterase, PA-phosphatase related
Bt4C1_RS06730	COG2409	Drug exporters of the RND superfamily
Bt4C1_RS06740	COG0564	pseudouridine synthase activity
Bt4C1_RS06750	COG2340	Cysteine-rich secretory protein family
Bt4C1_RS06755	COG0247	lactate metabolic process
Bt4C1_RS06760	COG0277	FAD linked oxidase domain protein
Bt4C1_RS06765	COG3835	regulator
Bt4C1_RS06775	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS06780	COG5002	protein histidine kinase activity
Bt4C1_RS06785	COG2186	Transcriptional regulator
Bt4C1_RS06805	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Bt4C1_RS06815	COG2116	formate transmembrane transporter activity
Bt4C1_RS06820	COG0861	Integral membrane protein TerC family
Bt4C1_RS06825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Bt4C1_RS06835	COG2030	dehydratase
Bt4C1_RS06855	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS06860	COG3243	poly(R)-hydroxyalkanoic acid synthase
Bt4C1_RS06870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Bt4C1_RS06885	COG1840	ABC-type Fe3 transport system, periplasmic component
Bt4C1_RS06890	COG3842	ATPase activity
Bt4C1_RS06915	COG1349	DNA-binding transcription factor activity
Bt4C1_RS06930	COG0235	Class ii aldolase
Bt4C1_RS06940	COG2861	carbohydrate metabolic process
Bt4C1_RS06950	COG3852	Histidine kinase
Bt4C1_RS06955	COG1846	Transcriptional regulator
Bt4C1_RS06965	COG2318	DinB family
Bt4C1_RS06975	COG5002	protein histidine kinase activity
Bt4C1_RS06985	COG0720	synthase
Bt4C1_RS07000	COG4873	Protein conserved in bacteria
Bt4C1_RS07030	COG1780	Probably involved in ribonucleotide reductase function
Bt4C1_RS07035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bt4C1_RS07040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bt4C1_RS07045	COG1725	Transcriptional regulator
Bt4C1_RS07050	COG1131	(ABC) transporter
Bt4C1_RS07060	COG1131	(ABC) transporter
Bt4C1_RS07075	COG2801	Transposase and inactivated derivatives
Bt4C1_RS07090	COG1522	sequence-specific DNA binding
Bt4C1_RS07100	COG1335	isochorismatase
Bt4C1_RS07110	COG1619	proteins homologs of microcin C7 resistance protein MccF
Bt4C1_RS07115	COG2070	2-Nitropropane dioxygenase
Bt4C1_RS07120	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
Bt4C1_RS07130	COG1696	Membrane protein involved in D-alanine export
Bt4C1_RS07155	COG0716	FMN binding
Bt4C1_RS07210	COG1846	Transcriptional regulator
Bt4C1_RS07220	COG1301	dicarboxylic acid transport
Bt4C1_RS07225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Bt4C1_RS07230	COG4709	membrane
Bt4C1_RS07235	COG3874	Sporulation protein YtfJ
Bt4C1_RS07255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Bt4C1_RS07260	COG0028	Belongs to the TPP enzyme family
Bt4C1_RS07265	COG0440	acetolactate synthase activity
Bt4C1_RS07340	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Bt4C1_RS07355	COG1183	phosphatidylcholine synthase activity
Bt4C1_RS07360	COG1368	sulfuric ester hydrolase activity
Bt4C1_RS07370	COG0019	diaminopimelate decarboxylase activity
Bt4C1_RS07390	COG0529	Catalyzes the synthesis of activated sulfate
Bt4C1_RS07395	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Bt4C1_RS07415	COG1648	precorrin-2 dehydrogenase activity
Bt4C1_RS07420	COG0733	neurotransmitter:sodium symporter activity
Bt4C1_RS07440	COG1757	Na H antiporter
Bt4C1_RS07455	COG4758	membrane
Bt4C1_RS07460	COG4585	Histidine kinase
Bt4C1_RS07465	COG2197	response regulator
Bt4C1_RS07475	COG1114	Component of the transport system for branched-chain amino acids
Bt4C1_RS07520	COG0730	response to heat
Bt4C1_RS07525	COG0306	phosphate transporter
Bt4C1_RS07530	COG1392	Phosphate transport regulator
Bt4C1_RS07535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bt4C1_RS07550	COG3852	Histidine kinase
Bt4C1_RS07555	COG1801	Protein of unknown function DUF72
Bt4C1_RS07565	COG0582	viral genome integration into host DNA
Bt4C1_RS07570	COG5002	protein histidine kinase activity
Bt4C1_RS07585	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Bt4C1_RS07585	COG0392	lysyltransferase activity
Bt4C1_RS07600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Bt4C1_RS07605	COG1686	Belongs to the peptidase S11 family
Bt4C1_RS07610	COG2715	membrane protein required for spore maturation
Bt4C1_RS07615	COG0700	Nucleoside recognition
Bt4C1_RS07620	COG1187	pseudouridine synthase activity
Bt4C1_RS07630	COG1333	cytochrome c biogenesis protein
Bt4C1_RS07635	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Bt4C1_RS07640	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS07645	COG5002	protein histidine kinase activity
Bt4C1_RS07650	COG2096	Adenosyltransferase
Bt4C1_RS07655	COG4942	peptidase
Bt4C1_RS07665	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
Bt4C1_RS07670	COG1141	Ferredoxin
Bt4C1_RS07680	COG0514	ATP-dependent DNA helicase (RecQ)
Bt4C1_RS07685	COG1266	CAAX protease self-immunity
Bt4C1_RS07695	COG1408	metallophosphoesterase
Bt4C1_RS07700	COG0789	Transcriptional regulator
Bt4C1_RS07710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Bt4C1_RS07730	COG0492	ferredoxin-NADP+ reductase activity
Bt4C1_RS07735	COG0252	asparaginase activity
Bt4C1_RS07800	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Bt4C1_RS07815	COG0142	geranyltranstransferase activity
Bt4C1_RS07825	COG0142	geranyltranstransferase activity
Bt4C1_RS07850	COG0457	Tetratricopeptide repeat
Bt4C1_RS07870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Bt4C1_RS07875	COG2010	Cytochrome c
Bt4C1_RS07875	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Bt4C1_RS07880	COG4347	Protein of unknown function (DUF1405)
Bt4C1_RS07895	COG2738	Putative neutral zinc metallopeptidase
Bt4C1_RS07905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_RS07910	COG1694	Mazg nucleotide pyrophosphohydrolase
Bt4C1_RS07930	COG0438	transferase activity, transferring glycosyl groups
Bt4C1_RS07965	COG1199	ATP-dependent helicase activity
Bt4C1_RS07965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Bt4C1_RS07985	COG3935	DnaD domain protein
Bt4C1_RS07990	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Bt4C1_RS08000	COG4499	WXG100 protein secretion system (Wss), protein YukC
Bt4C1_RS08000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bt4C1_RS08055	COG0116	Belongs to the methyltransferase superfamily
Bt4C1_RS08065	COG1199	ATP-dependent helicase activity
Bt4C1_RS08070	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Bt4C1_RS08080	COG3173	Aminoglycoside phosphotransferase
Bt4C1_RS08090	COG0024	Methionine aminopeptidase
Bt4C1_RS08100	COG2233	PERMEase
Bt4C1_RS08105	COG2311	Membrane
Bt4C1_RS08110	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Bt4C1_RS08120	COG0456	acetyltransferase
Bt4C1_RS08155	COG0754	glutathionylspermidine amidase activity
Bt4C1_RS08170	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bt4C1_RS08195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Bt4C1_RS08210	COG1215	transferase activity, transferring glycosyl groups
Bt4C1_RS08215	COG0438	transferase activity, transferring glycosyl groups
Bt4C1_RS08230	COG0454	-acetyltransferase
Bt4C1_RS08250	COG0328	RNA-DNA hybrid ribonuclease activity
Bt4C1_RS08285	COG3403	YqcI/YcgG family
Bt4C1_RS08290	COG1280	lysine exporter protein (LysE YggA)
Bt4C1_RS08310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Bt4C1_RS08315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Bt4C1_RS08325	COG0475	glutathione-regulated potassium exporter activity
Bt4C1_RS08330	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Bt4C1_RS08335	COG0789	Transcriptional regulator
Bt4C1_RS08335	COG4978	Transcriptional regulator
Bt4C1_RS08345	COG2323	membrane
Bt4C1_RS08350	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Bt4C1_RS08385	COG1923	regulation of RNA biosynthetic process
Bt4C1_RS08395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Bt4C1_RS08400	COG1360	Flagellar Motor Protein
Bt4C1_RS08405	COG2201	protein-glutamate methylesterase activity
Bt4C1_RS08410	COG2198	Histidine kinase
Bt4C1_RS08410	COG0643	Histidine kinase
Bt4C1_RS08415	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bt4C1_RS08415	COG1776	CheC inhibitor of MCP methylation
Bt4C1_RS08430	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Bt4C1_RS08450	COG1256	bacterial-type flagellum assembly
Bt4C1_RS08455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bt4C1_RS08475	COG1815	bacterial-type flagellum-dependent cell motility
Bt4C1_RS08480	COG1558	bacterial-type flagellum-dependent cell motility
Bt4C1_RS08490	COG1766	The M ring may be actively involved in energy transduction
Bt4C1_RS08495	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bt4C1_RS08505	COG1157	protein secretion by the type III secretion system
Bt4C1_RS08540	COG0835	chemotaxis
Bt4C1_RS08540	COG0784	Response regulator, receiver
Bt4C1_RS08550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bt4C1_RS08555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bt4C1_RS08560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bt4C1_RS08565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bt4C1_RS08570	COG0741	lytic transglycosylase activity
Bt4C1_RS08580	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bt4C1_RS08585	COG1776	CheC inhibitor of MCP methylation
Bt4C1_RS08585	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bt4C1_RS08595	COG1338	Plays a role in the flagellum-specific transport system
Bt4C1_RS08600	COG1987	bacterial-type flagellum assembly
Bt4C1_RS08610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Bt4C1_RS08615	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Bt4C1_RS08620	COG1419	protein localization to endoplasmic reticulum
Bt4C1_RS08625	COG4786	Flagellar basal body rod
Bt4C1_RS08630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Bt4C1_RS08635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Bt4C1_RS08665	COG2329	Antibiotic biosynthesis monooxygenase
Bt4C1_RS08695	COG0583	DNA-binding transcription factor activity
Bt4C1_RS08715	COG1234	tRNA 3'-trailer cleavage
Bt4C1_RS08735	COG1686	Belongs to the peptidase S11 family
Bt4C1_RS08745	COG0406	alpha-ribazole phosphatase activity
Bt4C1_RS08765	COG1846	Transcriptional regulator
Bt4C1_RS08775	COG0367	asparagine synthase
Bt4C1_RS08810	COG0523	cobalamin synthesis protein
Bt4C1_RS08815	COG0701	Predicted permease
Bt4C1_RS08830	COG1757	Na H antiporter
Bt4C1_RS08835	COG0789	Transcriptional regulator
Bt4C1_RS08865	COG0534	Mate efflux family protein
Bt4C1_RS08870	COG3340	Belongs to the peptidase S51 family
Bt4C1_RS08890	COG0785	Cytochrome C biogenesis protein
Bt4C1_RS08895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bt4C1_RS08905	COG0457	Tetratricopeptide repeat
Bt4C1_RS08925	COG2733	membrane
Bt4C1_RS08960	COG1131	(ABC) transporter
Bt4C1_RS08975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bt4C1_RS08980	COG0528	UMP kinase activity
Bt4C1_RS08990	COG1027	Aspartate ammonia-lyase
Bt4C1_RS08995	COG0281	malic enzyme
Bt4C1_RS09000	COG4191	Histidine kinase
Bt4C1_RS09005	COG0784	Response regulator, receiver
Bt4C1_RS09010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Bt4C1_RS09065	COG1695	Transcriptional regulator
Bt4C1_RS09075	COG0477	Major facilitator Superfamily
Bt4C1_RS09085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Bt4C1_RS09090	COG2223	nitrite transmembrane transporter activity
Bt4C1_RS09095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Bt4C1_RS09115	COG0733	neurotransmitter:sodium symporter activity
Bt4C1_RS09125	COG5566	PFAM Mor transcription activator
Bt4C1_RS09130	COG2323	membrane
Bt4C1_RS09150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bt4C1_RS09160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Bt4C1_RS09165	COG0028	Belongs to the TPP enzyme family
Bt4C1_RS09185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Bt4C1_RS09210	COG2814	Major facilitator Superfamily
Bt4C1_RS09215	COG3384	dioxygenase
Bt4C1_RS09230	COG3279	Response regulator of the LytR AlgR family
Bt4C1_RS09235	COG0427	acetyl-CoA hydrolase
Bt4C1_RS09255	COG4166	transmembrane transport
Bt4C1_RS09260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_RS09280	COG1914	H( )-stimulated, divalent metal cation uptake system
Bt4C1_RS09295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Bt4C1_RS09305	COG0531	amino acid
Bt4C1_RS09325	COG2309	aminopeptidase activity
Bt4C1_RS09340	COG0456	acetyltransferase
Bt4C1_RS09355	COG1309	transcriptional regulator
Bt4C1_RS09360	COG2390	Transcriptional regulator
Bt4C1_RS09370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_RS09375	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Bt4C1_RS09380	COG0295	cytidine deaminase activity
Bt4C1_RS09390	COG2801	Transposase and inactivated derivatives
Bt4C1_RS09425	COG4846	Membrane protein involved in cytochrome C biogenesis
Bt4C1_RS09435	COG0006	proline dipeptidase activity
Bt4C1_RS09445	COG2132	Multicopper oxidase
Bt4C1_RS09455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Bt4C1_RS09475	COG1114	Component of the transport system for branched-chain amino acids
Bt4C1_RS09485	COG2372	response to copper ion
Bt4C1_RS09485	COG1276	copper resistance
Bt4C1_RS09490	COG4549	nuclear export factor GLE1
Bt4C1_RS09495	COG0697	spore germination
Bt4C1_RS09500	COG0583	DNA-binding transcription factor activity
Bt4C1_RS09505	COG1959	2 iron, 2 sulfur cluster binding
Bt4C1_RS09510	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Bt4C1_RS09515	COG0778	Nitroreductase
Bt4C1_RS09530	COG0628	permease
Bt4C1_RS09540	COG1231	oxidoreductase activity
Bt4C1_RS09545	COG0523	cobalamin synthesis protein
Bt4C1_RS09555	COG0411	ABC transporter
Bt4C1_RS09575	COG0583	DNA-binding transcription factor activity
Bt4C1_RS09585	COG1942	4-Oxalocrotonate Tautomerase
Bt4C1_RS09605	COG1271	oxidase subunit
Bt4C1_RS09610	COG1294	oxidase, subunit
Bt4C1_RS09615	COG4988	ABC transporter
Bt4C1_RS09620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Bt4C1_RS09630	COG1216	Glycosyl transferase, family 2
Bt4C1_RS09670	COG1686	Belongs to the peptidase S11 family
Bt4C1_RS09685	COG1388	LysM domain
Bt4C1_RS09685	COG0791	NLP P60 protein
Bt4C1_RS09695	COG1132	(ABC) transporter
Bt4C1_RS09700	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS09705	COG5002	protein histidine kinase activity
Bt4C1_RS09710	COG0300	oxidoreductase activity
Bt4C1_RS09715	COG4122	O-methyltransferase activity
Bt4C1_RS09750	COG0460	homoserine dehydrogenase
Bt4C1_RS09775	COG1316	TRANSCRIPTIONal
Bt4C1_RS09790	COG1285	pathogenesis
Bt4C1_RS09815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Bt4C1_RS09825	COG1082	Xylose isomerase domain protein TIM barrel
Bt4C1_RS09835	COG2814	Major facilitator Superfamily
Bt4C1_RS09840	COG1279	arginine transmembrane transporter activity
Bt4C1_RS09845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_RS09855	COG1752	Esterase of the alpha-beta hydrolase superfamily
Bt4C1_RS09885	COG0577	efflux transmembrane transporter activity
Bt4C1_RS09890	COG2002	toxin-antitoxin pair type II binding
Bt4C1_RS09895	COG1404	Belongs to the peptidase S8 family
Bt4C1_RS09900	COG0640	Transcriptional regulator
Bt4C1_RS09905	COG0667	Aldo Keto reductase
Bt4C1_RS09910	COG2814	Major facilitator Superfamily
Bt4C1_RS09935	COG0840	transmembrane signaling receptor activity
Bt4C1_RS09950	COG3949	Membrane
Bt4C1_RS09955	COG0783	Belongs to the Dps family
Bt4C1_RS09970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Bt4C1_RS09980	COG1231	oxidoreductase activity
Bt4C1_RS09985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_RS09990	COG4989	oxidoreductase activity
Bt4C1_RS09995	COG0523	cobalamin synthesis protein
Bt4C1_RS10000	COG0456	acetyltransferase
Bt4C1_RS10005	COG0803	Belongs to the bacterial solute-binding protein 9 family
Bt4C1_RS10015	COG0702	epimerase
Bt4C1_RS10025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Bt4C1_RS10035	COG4166	transmembrane transport
Bt4C1_RS10050	COG0406	alpha-ribazole phosphatase activity
Bt4C1_RS10060	COG5337	Spore coat protein CotH
Bt4C1_RS10065	COG1051	belongs to the nudix hydrolase family
Bt4C1_RS10070	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_RS10075	COG2244	polysaccharide biosynthetic process
Bt4C1_RS10085	COG0701	Predicted permease
Bt4C1_RS10090	COG3689	TIGRFAM TIGR03943 family protein
Bt4C1_RS10095	COG1607	acyl-coa hydrolase
Bt4C1_RS10100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bt4C1_RS10115	COG0702	epimerase
Bt4C1_RS10120	COG2839	Protein conserved in bacteria
Bt4C1_RS10125	COG1253	flavin adenine dinucleotide binding
Bt4C1_RS10150	COG1114	Component of the transport system for branched-chain amino acids
Bt4C1_RS10155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bt4C1_RS10170	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_RS10180	COG1876	peptidase activity
Bt4C1_RS10195	COG2211	Major facilitator Superfamily
Bt4C1_RS10210	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_RS10220	COG0561	phosphatase activity
Bt4C1_RS10225	COG1846	Transcriptional regulator
Bt4C1_RS10230	COG2814	Major facilitator Superfamily
Bt4C1_RS10240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Bt4C1_RS10245	COG4106	trans-aconitate 2-methyltransferase activity
Bt4C1_RS10260	COG1819	glycosyl
Bt4C1_RS10265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_RS10270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_RS10300	COG0456	acetyltransferase
Bt4C1_RS10430	COG3874	Sporulation protein YtfJ
Bt4C1_RS10455	COG2226	methyltransferase
Bt4C1_RS10475	COG1082	Xylose isomerase domain protein TIM barrel
Bt4C1_RS10480	COG0346	lactoylglutathione lyase activity
Bt4C1_RS10490	COG0604	alcohol dehydrogenase
Bt4C1_RS10495	COG1595	DNA-templated transcription, initiation
Bt4C1_RS10505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Bt4C1_RS10515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Bt4C1_RS10515	COG0426	domain, Protein
Bt4C1_RS10525	COG0386	Belongs to the glutathione peroxidase family
Bt4C1_RS10530	COG1305	Transglutaminase-like
Bt4C1_RS10535	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
Bt4C1_RS10540	COG0714	Associated with various cellular activities
Bt4C1_RS10545	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Bt4C1_RS10550	COG1140	nitrate reductase beta subunit
Bt4C1_RS10555	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Bt4C1_RS10560	COG2181	nitrate reductase activity
Bt4C1_RS10565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bt4C1_RS10570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Bt4C1_RS10575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bt4C1_RS10580	COG0303	'Molybdopterin
Bt4C1_RS10585	COG0314	molybdopterin synthase activity
Bt4C1_RS10595	COG2223	nitrite transmembrane transporter activity
Bt4C1_RS10610	COG1648	precorrin-2 dehydrogenase activity
Bt4C1_RS10615	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
Bt4C1_RS10620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Bt4C1_RS10620	COG1587	Uroporphyrinogen-III synthase
Bt4C1_RS10625	COG2146	nitrite reductase [NAD(P)H] activity
Bt4C1_RS10630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Bt4C1_RS10635	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
Bt4C1_RS10670	COG2359	stage V sporulation protein S
Bt4C1_RS10685	COG0457	Tetratricopeptide repeat
Bt4C1_RS10700	COG1418	mRNA catabolic process
Bt4C1_RS10705	COG0488	(ABC) transporter
Bt4C1_RS10720	COG0629	single-stranded DNA binding
Bt4C1_RS10735	COG1413	lyase activity
Bt4C1_RS10750	COG2136	Putative SAM-dependent methyltransferase
Bt4C1_RS10750	COG2521	methyltransferase
Bt4C1_RS10755	COG0018	arginyl-trna synthetase
Bt4C1_RS10790	COG0017	Asparaginyl-tRNA synthetase
Bt4C1_RS10795	COG0733	neurotransmitter:sodium symporter activity
Bt4C1_RS10820	COG2610	gluconate transmembrane transporter activity
Bt4C1_RS10830	COG1794	racemase activity, acting on amino acids and derivatives
Bt4C1_RS10840	COG0456	acetyltransferase
Bt4C1_RS10850	COG3655	Transcriptional regulator
Bt4C1_RS10855	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Bt4C1_RS10865	COG1131	(ABC) transporter
Bt4C1_RS10880	COG0546	phosphoglycolate phosphatase activity
Bt4C1_RS10895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Bt4C1_RS10910	COG0768	penicillin binding
Bt4C1_RS10920	COG0204	Acyl-transferase
Bt4C1_RS10925	COG1272	protein, Hemolysin III
Bt4C1_RS10935	COG0805	protein transport
Bt4C1_RS10945	COG1307	EDD domain protein, DegV family
Bt4C1_RS10955	COG1999	signal sequence binding
Bt4C1_RS10960	COG0071	Belongs to the small heat shock protein (HSP20) family
Bt4C1_RS10965	COG0367	asparagine synthase
Bt4C1_RS10980	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_RS10985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bt4C1_RS10990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Bt4C1_RS11005	COG1335	isochorismatase
Bt4C1_RS11010	COG1051	belongs to the nudix hydrolase family
Bt4C1_RS11015	COG0668	transmembrane transport
Bt4C1_RS11020	COG4585	Histidine kinase
Bt4C1_RS11020	COG2203	Gaf domain
Bt4C1_RS11025	COG2197	response regulator
Bt4C1_RS11030	COG1737	Transcriptional regulator
Bt4C1_RS11035	COG0384	phenazine biosynthesis protein PhzF
Bt4C1_RS11040	COG1064	alcohol dehydrogenase
Bt4C1_RS11065	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Bt4C1_RS11100	COG1125	glycine betaine transport
Bt4C1_RS11100	COG0517	IMP dehydrogenase activity
Bt4C1_RS11105	COG1174	glycine betaine transport
Bt4C1_RS11140	COG1253	flavin adenine dinucleotide binding
Bt4C1_RS11145	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_RS11150	COG5506	Protein of unknown function (DUF1694)
Bt4C1_RS11165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Bt4C1_RS11170	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Bt4C1_RS11175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Bt4C1_RS11180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Bt4C1_RS11185	COG0456	acetyltransferase
Bt4C1_RS11190	COG3829	transcription factor binding
Bt4C1_RS11195	COG1509	lysine 2,3-aminomutase activity
Bt4C1_RS11225	COG0515	serine threonine protein kinase
Bt4C1_RS11225	COG3064	Membrane
Bt4C1_RS11225	COG4991	sh3 domain protein
Bt4C1_RS11235	COG0671	phosphoesterase, PA-phosphatase related
Bt4C1_RS11240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Bt4C1_RS11245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bt4C1_RS11320	COG0300	oxidoreductase activity
Bt4C1_RS11340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bt4C1_RS11340	COG4499	WXG100 protein secretion system (Wss), protein YukC
Bt4C1_RS11350	COG2814	Major facilitator Superfamily
Bt4C1_RS11355	COG4841	protein insertion into membrane
Bt4C1_RS11360	COG0372	Belongs to the citrate synthase family
Bt4C1_RS11365	COG2079	MmgE PrpD family protein
Bt4C1_RS11370	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Bt4C1_RS11375	COG1960	acyl-CoA dehydrogenase activity
Bt4C1_RS11380	COG2084	Dehydrogenase
Bt4C1_RS11390	COG1280	lysine exporter protein (LysE YggA)
Bt4C1_RS11395	COG1024	Enoyl-CoA hydratase
Bt4C1_RS11410	COG0420	3'-5' exonuclease activity
Bt4C1_RS11415	COG0419	ATPase involved in DNA repair
Bt4C1_RS11435	COG2223	nitrite transmembrane transporter activity
Bt4C1_RS11440	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS11445	COG1169	isochorismate synthase
Bt4C1_RS11450	COG1021	2,3-dihydroxybenzoate-AMP ligase
Bt4C1_RS11455	COG1535	isochorismatase
Bt4C1_RS11455	COG3433	isochorismatase activity
Bt4C1_RS11460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Bt4C1_RS11465	COG3251	PFAM MbtH domain protein
Bt4C1_RS11470	COG2814	Major facilitator Superfamily
Bt4C1_RS11485	COG0776	regulation of translation
Bt4C1_RS11495	COG2318	DinB family
Bt4C1_RS11505	COG1115	amino acid carrier protein
Bt4C1_RS11525	COG1187	pseudouridine synthase activity
Bt4C1_RS11530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Bt4C1_RS11535	COG1136	(ABC) transporter
Bt4C1_RS11575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bt4C1_RS11590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_RS11625	COG1247	-acetyltransferase
Bt4C1_RS11650	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Bt4C1_RS11660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_RS11690	COG0583	DNA-binding transcription factor activity
Bt4C1_RS11695	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Bt4C1_RS11705	COG0583	DNA-binding transcription factor activity
Bt4C1_RS11710	COG2258	MOSC domain
Bt4C1_RS11725	COG1132	(ABC) transporter
Bt4C1_RS11730	COG1132	(ABC) transporter
Bt4C1_RS11755	COG1396	sequence-specific DNA binding
Bt4C1_RS11785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Bt4C1_RS11790	COG1595	DNA-templated transcription, initiation
Bt4C1_RS11815	COG1649	PFAM Uncharacterised BCR, COG1649
Bt4C1_RS11840	COG2971	BadF BadG BcrA BcrD
Bt4C1_RS11850	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Bt4C1_RS11860	COG1846	Transcriptional regulator
Bt4C1_RS11950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bt4C1_RS11950	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bt4C1_RS12035	COG2002	toxin-antitoxin pair type II binding
Bt4C1_RS12075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Bt4C1_RS12185	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_RS12250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_RS12265	COG0500	methyltransferase
Bt4C1_RS12265	COG3615	Tellurite resistance protein tehB
Bt4C1_RS12275	COG2226	methyltransferase
Bt4C1_RS12280	COG3961	Belongs to the TPP enzyme family
Bt4C1_RS12315	COG2195	Cleaves the N-terminal amino acid of tripeptides
Bt4C1_RS12340	COG2002	toxin-antitoxin pair type II binding
Bt4C1_RS12350	COG0730	response to heat
Bt4C1_RS12360	COG1686	Belongs to the peptidase S11 family
Bt4C1_RS12375	COG2814	Major facilitator Superfamily
Bt4C1_RS12405	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS12450	COG0741	lytic transglycosylase activity
Bt4C1_RS12455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_RS12465	COG0456	acetyltransferase
Bt4C1_RS12475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Bt4C1_RS12480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Bt4C1_RS12485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Bt4C1_RS12500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Bt4C1_RS12510	COG2234	aminopeptidase activity
Bt4C1_RS12515	COG2814	Major facilitator Superfamily
Bt4C1_RS12560	COG1396	sequence-specific DNA binding
Bt4C1_RS12600	COG0768	penicillin binding
Bt4C1_RS12605	COG1595	DNA-templated transcription, initiation
Bt4C1_RS12615	COG0768	penicillin binding
Bt4C1_RS12620	COG0768	penicillin binding
Bt4C1_RS12630	COG1408	metallophosphoesterase
Bt4C1_RS12640	COG1131	(ABC) transporter
Bt4C1_RS12650	COG1309	transcriptional regulator
Bt4C1_RS12665	COG1960	acyl-CoA dehydrogenase activity
Bt4C1_RS12670	COG0439	Biotin carboxylase
Bt4C1_RS12675	COG0511	ligase activity, forming carbon-carbon bonds
Bt4C1_RS12680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Bt4C1_RS12685	COG1024	Enoyl-CoA hydratase
Bt4C1_RS12690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Bt4C1_RS12695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Bt4C1_RS12720	COG1686	Belongs to the peptidase S11 family
Bt4C1_RS12750	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Bt4C1_RS12765	COG3227	Zinc metalloprotease (Elastase)
Bt4C1_RS12770	COG2207	Transcriptional regulator
Bt4C1_RS12800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Bt4C1_RS12810	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS12815	COG1733	regulation of RNA biosynthetic process
Bt4C1_RS12860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_RS12875	COG1063	alcohol dehydrogenase
Bt4C1_RS12885	COG2323	membrane
Bt4C1_RS12895	COG0693	protein deglycase activity
Bt4C1_RS12905	COG3386	PFAM SMP-30 Gluconolaconase
Bt4C1_RS12910	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Bt4C1_RS12915	COG3773	Cell wall hydrolase
Bt4C1_RS12925	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS12930	COG2205	protein histidine kinase activity
Bt4C1_RS12935	COG0583	DNA-binding transcription factor activity
Bt4C1_RS12940	COG0667	Aldo Keto reductase
Bt4C1_RS12945	COG0488	(ABC) transporter
Bt4C1_RS12960	COG1136	(ABC) transporter
Bt4C1_RS12965	COG0577	efflux transmembrane transporter activity
Bt4C1_RS12990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_RS13000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Bt4C1_RS13055	COG2124	cytochrome p450
Bt4C1_RS13090	COG0561	phosphatase activity
Bt4C1_RS13095	COG5002	protein histidine kinase activity
Bt4C1_RS13100	COG0768	penicillin binding
Bt4C1_RS13110	COG1819	glycosyl
Bt4C1_RS13115	COG1794	racemase activity, acting on amino acids and derivatives
Bt4C1_RS13135	COG2205	protein histidine kinase activity
Bt4C1_RS13180	COG2169	Transcriptional regulator
Bt4C1_RS13205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Bt4C1_RS13210	COG0604	alcohol dehydrogenase
Bt4C1_RS13215	COG0671	phosphoesterase, PA-phosphatase related
Bt4C1_RS13220	COG0768	penicillin binding
Bt4C1_RS13250	COG1307	EDD domain protein, DegV family
Bt4C1_RS13295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_RS13300	COG0697	spore germination
Bt4C1_RS13325	COG0494	nUDIX hydrolase
Bt4C1_RS13335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Bt4C1_RS13345	COG2223	nitrite transmembrane transporter activity
Bt4C1_RS13360	COG0592	DNA-directed DNA polymerase activity
Bt4C1_RS13365	COG1051	belongs to the nudix hydrolase family
Bt4C1_RS13380	COG3878	Protein conserved in bacteria
Bt4C1_RS13400	COG4667	esterase of the alpha-beta hydrolase superfamily
Bt4C1_RS13440	COG0322	excinuclease ABC activity
Bt4C1_RS13475	COG1819	glycosyl
Bt4C1_RS13480	COG1819	glycosyl
Bt4C1_RS13495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bt4C1_RS13520	COG1011	Hydrolase
Bt4C1_RS13525	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS13530	COG5002	protein histidine kinase activity
Bt4C1_RS13545	COG1136	(ABC) transporter
Bt4C1_RS13550	COG0577	efflux transmembrane transporter activity
Bt4C1_RS13555	COG1073	alpha beta
Bt4C1_RS13560	COG0657	acetylesterase activity
Bt4C1_RS13565	COG0076	glutamate decarboxylase activity
Bt4C1_RS13580	COG1523	belongs to the glycosyl hydrolase 13 family
Bt4C1_RS13585	COG3227	Zinc metalloprotease (Elastase)
Bt4C1_RS13590	COG0737	Belongs to the 5'-nucleotidase family
Bt4C1_RS13610	COG0201	protein transport
Bt4C1_RS13615	COG0697	spore germination
Bt4C1_RS13620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_RS13655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_RS13670	COG2959	enzyme of heme biosynthesis
Bt4C1_RS13710	COG1309	transcriptional regulator
Bt4C1_RS13725	COG3284	Transcriptional regulator
Bt4C1_RS13740	COG1349	DNA-binding transcription factor activity
Bt4C1_RS13755	COG1959	2 iron, 2 sulfur cluster binding
Bt4C1_RS13770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Bt4C1_RS13775	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bt4C1_RS13780	COG0022	dehydrogenase e1 component
Bt4C1_RS13785	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Bt4C1_RS13795	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS13825	COG4176	ABC-type proline glycine betaine transport system permease component
Bt4C1_RS13830	COG0517	IMP dehydrogenase activity
Bt4C1_RS13830	COG4175	Glycine betaine
Bt4C1_RS13860	COG2153	protein acetylation
Bt4C1_RS13880	COG3397	chitin binding
Bt4C1_RS13885	COG1819	glycosyl
Bt4C1_RS13895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Bt4C1_RS13905	COG2205	protein histidine kinase activity
Bt4C1_RS13910	COG2226	methyltransferase
Bt4C1_RS13910	COG2267	carboxylic ester hydrolase activity
Bt4C1_RS13915	COG2315	Protein conserved in bacteria
Bt4C1_RS13965	COG0456	acetyltransferase
Bt4C1_RS13970	COG3973	AAA domain
Bt4C1_RS13985	COG0514	ATP-dependent DNA helicase (RecQ)
Bt4C1_RS14015	COG4637	Psort location Cytoplasmic, score
Bt4C1_RS14040	COG3397	chitin binding
Bt4C1_RS14055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Bt4C1_RS14060	COG1115	amino acid carrier protein
Bt4C1_RS14065	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_RS14070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Bt4C1_RS14080	COG3938	Belongs to the proline racemase family
Bt4C1_RS14085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bt4C1_RS14130	COG1078	dGTPase activity
Bt4C1_RS14135	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_RS14145	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
Bt4C1_RS14150	COG4166	transmembrane transport
Bt4C1_RS14160	COG4948	Mandelate Racemase Muconate Lactonizing
Bt4C1_RS14175	COG0667	Aldo Keto reductase
Bt4C1_RS14220	COG3850	Histidine kinase
Bt4C1_RS14220	COG5002	protein histidine kinase activity
Bt4C1_RS14225	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS14250	COG1164	Oligoendopeptidase f
Bt4C1_RS14255	COG1307	EDD domain protein, DegV family
Bt4C1_RS14295	COG2814	Major facilitator Superfamily
Bt4C1_RS14305	COG1664	Polymer-forming cytoskeletal
Bt4C1_RS14310	COG0789	Transcriptional regulator
Bt4C1_RS14315	COG4533	DNA binding
Bt4C1_RS14320	COG0477	Major facilitator Superfamily
Bt4C1_RS14320	COG2814	Major facilitator Superfamily
Bt4C1_RS14340	COG2261	transglycosylase associated protein
Bt4C1_RS14355	COG2226	methyltransferase
Bt4C1_RS14390	COG0436	Aminotransferase
Bt4C1_RS14395	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Bt4C1_RS14405	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Bt4C1_RS14465	COG0628	permease
Bt4C1_RS14480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bt4C1_RS14485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bt4C1_RS14515	COG2746	aminoglycoside 3-N-acetyltransferase activity
Bt4C1_RS14525	COG0697	spore germination
Bt4C1_RS14530	COG2318	DinB family
Bt4C1_RS14550	COG4912	Dna alkylation repair
Bt4C1_RS14555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Bt4C1_RS14560	COG0346	lactoylglutathione lyase activity
Bt4C1_RS14565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_RS14595	COG0861	Integral membrane protein TerC family
Bt4C1_RS14600	COG1368	sulfuric ester hydrolase activity
Bt4C1_RS14605	COG0488	(ABC) transporter
Bt4C1_RS14610	COG2409	Drug exporters of the RND superfamily
Bt4C1_RS14610	COG1033	growth of symbiont in host cell
Bt4C1_RS14615	COG1309	transcriptional regulator
Bt4C1_RS14630	COG0287	Prephenate dehydrogenase
Bt4C1_RS14645	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Bt4C1_RS14645	COG1605	Chorismate mutase
Bt4C1_RS14680	COG3584	3D domain protein
Bt4C1_RS14680	COG1388	LysM domain
Bt4C1_RS14710	COG1879	ABC-type sugar transport system periplasmic component
Bt4C1_RS14720	COG1172	Belongs to the binding-protein-dependent transport system permease family
Bt4C1_RS14730	COG2390	Transcriptional regulator
Bt4C1_RS14735	COG1070	Carbohydrate kinase
Bt4C1_RS14760	COG2329	Antibiotic biosynthesis monooxygenase
Bt4C1_RS14775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_RS14790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bt4C1_RS14795	COG4187	Peptidase family M20/M25/M40
Bt4C1_RS14800	COG1414	Transcriptional regulator
Bt4C1_RS14805	COG0833	amino acid
Bt4C1_RS14815	COG1690	Belongs to the RtcB family
Bt4C1_RS14820	COG3239	Fatty acid desaturase
Bt4C1_RS14830	COG2720	vancomycin resistance protein
Bt4C1_RS14835	COG1785	Belongs to the alkaline phosphatase family
Bt4C1_RS14845	COG3655	Transcriptional regulator
Bt4C1_RS14870	COG0346	lactoylglutathione lyase activity
Bt4C1_RS14890	COG0714	Associated with various cellular activities
Bt4C1_RS14915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Bt4C1_RS14920	COG0753	catalase activity
Bt4C1_RS14950	COG5444	nuclease activity
Bt4C1_RS14990	COG0778	Nitroreductase
Bt4C1_RS14995	COG1846	Transcriptional regulator
Bt4C1_RS15015	COG4884	unkown
Bt4C1_RS15015	COG3831	ATPase activity
Bt4C1_RS15025	COG1136	(ABC) transporter
Bt4C1_RS15045	COG2207	Transcriptional regulator
Bt4C1_RS15050	COG0456	acetyltransferase
Bt4C1_RS15060	COG2816	NAD+ diphosphatase activity
Bt4C1_RS15065	COG0697	spore germination
Bt4C1_RS15070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_RS15110	COG0730	response to heat
Bt4C1_RS15120	COG0833	amino acid
Bt4C1_RS15165	COG1329	Transcriptional regulator
Bt4C1_RS15175	COG5002	protein histidine kinase activity
Bt4C1_RS15200	COG0768	penicillin binding
Bt4C1_RS15230	COG1984	allophanate hydrolase subunit 2
Bt4C1_RS15235	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Bt4C1_RS15240	COG1414	Transcriptional regulator
Bt4C1_RS15255	COG0640	Transcriptional regulator
Bt4C1_RS15265	COG1960	acyl-CoA dehydrogenase activity
Bt4C1_RS15280	COG3314	Sporulation integral membrane protein YlbJ
Bt4C1_RS15300	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
Bt4C1_RS15320	COG0574	Belongs to the PEP-utilizing enzyme family
Bt4C1_RS15320	COG3848	Pyruvate phosphate dikinase
Bt4C1_RS15325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_RS15345	COG1063	alcohol dehydrogenase
Bt4C1_RS15360	COG0252	asparaginase activity
Bt4C1_RS15365	COG1396	sequence-specific DNA binding
Bt4C1_RS15385	COG5002	protein histidine kinase activity
Bt4C1_RS15410	COG2207	Transcriptional regulator
Bt4C1_RS15415	COG0322	excinuclease ABC activity
Bt4C1_RS15420	COG0531	amino acid
Bt4C1_RS15425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bt4C1_RS15435	COG0531	amino acid
Bt4C1_RS15440	COG0697	spore germination
Bt4C1_RS15445	COG0784	Response regulator, receiver
Bt4C1_RS15450	COG4191	Histidine kinase
Bt4C1_RS15460	COG1115	amino acid carrier protein
Bt4C1_RS15470	COG2124	cytochrome p450
Bt4C1_RS15490	COG2267	carboxylic ester hydrolase activity
Bt4C1_RS15495	COG1335	isochorismatase
Bt4C1_RS15515	COG0583	DNA-binding transcription factor activity
Bt4C1_RS15520	COG1846	Transcriptional regulator
Bt4C1_RS15525	COG0598	Magnesium transport protein CorA
Bt4C1_RS15545	COG1073	alpha beta
Bt4C1_RS15565	COG0415	Belongs to the DNA photolyase family
Bt4C1_RS15570	COG0288	reversible hydration of carbon dioxide
Bt4C1_RS15580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Bt4C1_RS15585	COG5609	conserved protein (DUF2294)
Bt4C1_RS15600	COG1575	Belongs to the MenA family. Type 1 subfamily
Bt4C1_RS15605	COG0803	Belongs to the bacterial solute-binding protein 9 family
Bt4C1_RS15610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Bt4C1_RS15615	COG1121	(ABC) transporter
Bt4C1_RS15635	COG0798	PFAM Bile acid sodium symporter
Bt4C1_RS15640	COG0346	lactoylglutathione lyase activity
Bt4C1_RS15645	COG0640	Transcriptional regulator
Bt4C1_RS15665	COG0346	lactoylglutathione lyase activity
Bt4C1_RS15690	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS15695	COG5002	protein histidine kinase activity
Bt4C1_RS15695	COG3850	Histidine kinase
Bt4C1_RS15730	COG0277	FAD linked oxidase domain protein
Bt4C1_RS15740	COG1136	(ABC) transporter
Bt4C1_RS15775	COG2814	Major facilitator Superfamily
Bt4C1_RS15790	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Bt4C1_RS15805	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Bt4C1_RS15825	COG0577	efflux transmembrane transporter activity
Bt4C1_RS15830	COG5002	protein histidine kinase activity
Bt4C1_RS15830	COG3850	Histidine kinase
Bt4C1_RS15845	COG1846	Transcriptional regulator
Bt4C1_RS15850	COG0456	acetyltransferase
Bt4C1_RS15855	COG2808	Putative FMN-binding domain
Bt4C1_RS15860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_RS15875	COG1619	proteins homologs of microcin C7 resistance protein MccF
Bt4C1_RS15895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Bt4C1_RS15915	COG0662	Cupin 2, conserved barrel domain protein
Bt4C1_RS15920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bt4C1_RS15920	COG2207	Transcriptional regulator
Bt4C1_RS15935	COG3409	Peptidoglycan-binding domain 1 protein
Bt4C1_RS15935	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_RS15950	COG2814	Major facilitator Superfamily
Bt4C1_RS16005	COG4282	regulation of fungal-type cell wall biogenesis
Bt4C1_RS16060	COG5444	nuclease activity
Bt4C1_RS16085	COG1876	peptidase activity
Bt4C1_RS16090	COG2843	Capsule synthesis protein
Bt4C1_RS16100	COG0477	Major facilitator Superfamily
Bt4C1_RS16115	COG1846	Transcriptional regulator
Bt4C1_RS16120	COG2814	Major facilitator Superfamily
Bt4C1_RS16130	COG2031	fatty acid transporter
Bt4C1_RS16140	COG2249	NAD(P)H dehydrogenase (quinone) activity
Bt4C1_RS16195	COG1288	antiporter activity
Bt4C1_RS16200	COG2356	endonuclease I
Bt4C1_RS16210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Bt4C1_RS16215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Bt4C1_RS16235	COG1733	regulation of RNA biosynthetic process
Bt4C1_RS16240	COG0778	Nitroreductase
Bt4C1_RS16270	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS16280	COG1131	(ABC) transporter
Bt4C1_RS16305	COG1011	Hydrolase
Bt4C1_RS16310	COG2365	Tyrosine phosphatase family
Bt4C1_RS16325	COG1051	belongs to the nudix hydrolase family
Bt4C1_RS16335	COG0346	lactoylglutathione lyase activity
Bt4C1_RS16340	COG1940	carbohydrate kinase activity
Bt4C1_RS16345	COG0738	Major facilitator superfamily
Bt4C1_RS16350	COG0110	maltose O-acetyltransferase activity
Bt4C1_RS16365	COG0628	permease
Bt4C1_RS16400	COG0500	methyltransferase
Bt4C1_RS16410	COG0477	Major facilitator Superfamily
Bt4C1_RS16440	COG1253	flavin adenine dinucleotide binding
Bt4C1_RS16445	COG0789	Transcriptional regulator
Bt4C1_RS16450	COG0697	spore germination
Bt4C1_RS16465	COG1357	PFAM Pentapeptide repeats (8 copies)
Bt4C1_RS16470	COG3813	Protein conserved in bacteria
Bt4C1_RS16475	COG2706	6-phosphogluconolactonase activity
Bt4C1_RS16480	COG1070	Carbohydrate kinase
Bt4C1_RS16485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Bt4C1_RS16490	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Bt4C1_RS16495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Bt4C1_RS16500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Bt4C1_RS16515	COG0814	amino acid
Bt4C1_RS16545	COG1733	regulation of RNA biosynthetic process
Bt4C1_RS16550	COG2188	Transcriptional regulator
Bt4C1_RS16555	COG0673	inositol 2-dehydrogenase activity
Bt4C1_RS16575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_RS16600	COG0384	phenazine biosynthesis protein PhzF
Bt4C1_RS16610	COG0318	PFAM AMP-dependent synthetase and ligase
Bt4C1_RS16615	COG2249	NAD(P)H dehydrogenase (quinone) activity
Bt4C1_RS16620	COG1733	regulation of RNA biosynthetic process
Bt4C1_RS16625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Bt4C1_RS16650	COG1191	sigma factor activity
Bt4C1_RS16695	COG1151	hydroxylamine reductase activity
Bt4C1_RS16700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_RS16725	COG2072	flavoprotein involved in K transport
Bt4C1_RS16755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_RS16760	COG0604	alcohol dehydrogenase
Bt4C1_RS16765	COG1113	amino acid transport
Bt4C1_RS16770	COG2814	Major facilitator Superfamily
Bt4C1_RS16800	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Bt4C1_RS16805	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Bt4C1_RS16815	COG1247	-acetyltransferase
Bt4C1_RS16820	COG3739	integral membrane protein
Bt4C1_RS16850	COG0583	DNA-binding transcription factor activity
Bt4C1_RS16870	COG1193	negative regulation of DNA recombination
Bt4C1_RS16885	COG2162	N-hydroxyarylamine O-acetyltransferase activity
Bt4C1_RS16890	COG1164	Oligoendopeptidase f
Bt4C1_RS16895	COG2957	Belongs to the agmatine deiminase family
Bt4C1_RS16920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Bt4C1_RS16930	COG2271	Major facilitator Superfamily
Bt4C1_RS16945	COG0584	glycerophosphoryl diester phosphodiesterase
Bt4C1_RS16955	COG0640	Transcriptional regulator
Bt4C1_RS16960	COG0604	alcohol dehydrogenase
Bt4C1_RS16970	COG0457	Tetratricopeptide repeat
Bt4C1_RS16980	COG0385	Bile acid
Bt4C1_RS16985	COG0277	FAD linked oxidase domain protein
Bt4C1_RS17005	COG1252	NADH dehydrogenase
Bt4C1_RS17020	COG4641	Protein conserved in bacteria
Bt4C1_RS17030	COG2089	acid synthase
Bt4C1_RS17045	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Bt4C1_RS17050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Bt4C1_RS17055	COG1088	dTDP-glucose 4,6-dehydratase activity
Bt4C1_RS17065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Bt4C1_RS17070	COG0463	Glycosyl transferase, family 2
Bt4C1_RS17075	COG0463	Glycosyl transferase, family 2
Bt4C1_RS17085	COG0823	Involved in the tonB-independent uptake of proteins
Bt4C1_RS17090	COG3397	chitin binding
Bt4C1_RS17100	COG0697	spore germination
Bt4C1_RS17120	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Bt4C1_RS17140	COG0457	Tetratricopeptide repeat
Bt4C1_RS17195	COG0488	(ABC) transporter
Bt4C1_RS17200	COG1309	transcriptional regulator
Bt4C1_RS17215	COG1876	peptidase activity
Bt4C1_RS17240	COG3852	Histidine kinase
Bt4C1_RS17250	COG1285	pathogenesis
Bt4C1_RS17260	COG2514	catechol 2,3-dioxygenase activity
Bt4C1_RS17265	COG2720	vancomycin resistance protein
Bt4C1_RS17300	COG0716	FMN binding
Bt4C1_RS17310	COG0494	nUDIX hydrolase
Bt4C1_RS17330	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS17340	COG0165	Argininosuccinate lyase
Bt4C1_RS17355	COG4145	pantothenate transmembrane transporter activity
Bt4C1_RS17365	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_RS17370	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS17380	COG1657	PFAM Prenyltransferase squalene oxidase
Bt4C1_RS17385	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
Bt4C1_RS17390	COG2962	Rard protein
Bt4C1_RS17395	COG3326	Membrane
Bt4C1_RS17410	COG0489	protein tyrosine kinase activity
Bt4C1_RS17420	COG0314	molybdopterin synthase activity
Bt4C1_RS17425	COG0303	'Molybdopterin
Bt4C1_RS17430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bt4C1_RS17435	COG2116	formate transmembrane transporter activity
Bt4C1_RS17445	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Bt4C1_RS17450	COG5609	conserved protein (DUF2294)
Bt4C1_RS17455	COG2427	Protein of unknown function (DUF1641)
Bt4C1_RS17460	COG3383	formate dehydrogenase (NAD+) activity
Bt4C1_RS17465	COG0697	spore germination
Bt4C1_RS17510	COG2226	methyltransferase
Bt4C1_RS17515	COG4166	transmembrane transport
Bt4C1_RS17525	COG4166	transmembrane transport
Bt4C1_RS17530	COG1301	dicarboxylic acid transport
Bt4C1_RS17535	COG1316	TRANSCRIPTIONal
Bt4C1_RS17545	COG1595	DNA-templated transcription, initiation
Bt4C1_RS17555	COG1131	(ABC) transporter
Bt4C1_RS17575	COG0673	inositol 2-dehydrogenase activity
Bt4C1_RS17580	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Bt4C1_RS17585	COG0187	DNA topoisomerase II activity
Bt4C1_RS17590	COG1832	CoA-binding protein
Bt4C1_RS17595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bt4C1_RS17600	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS17620	COG4841	protein insertion into membrane
Bt4C1_RS17625	COG0824	Thioesterase
Bt4C1_RS17650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bt4C1_RS17660	COG1132	(ABC) transporter
Bt4C1_RS17665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Bt4C1_RS17695	COG2211	Major facilitator Superfamily
Bt4C1_RS17705	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Bt4C1_RS17720	COG0183	Belongs to the thiolase family
Bt4C1_RS17725	COG0318	PFAM AMP-dependent synthetase and ligase
Bt4C1_RS17730	COG1268	BioY protein
Bt4C1_RS17735	COG0318	PFAM AMP-dependent synthetase and ligase
Bt4C1_RS17740	COG1396	sequence-specific DNA binding
Bt4C1_RS17775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_RS17785	COG5002	protein histidine kinase activity
Bt4C1_RS17790	COG0400	carboxylic ester hydrolase activity
Bt4C1_RS17795	COG0346	lactoylglutathione lyase activity
Bt4C1_RS17800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Bt4C1_RS17810	COG0069	glutamate synthase activity
Bt4C1_RS17815	COG1902	pentaerythritol trinitrate reductase activity
Bt4C1_RS17820	COG1329	Transcriptional regulator
Bt4C1_RS17825	COG0010	Belongs to the arginase family
Bt4C1_RS17875	COG4846	Membrane protein involved in cytochrome C biogenesis
Bt4C1_RS17880	COG0785	Cytochrome C biogenesis protein
Bt4C1_RS17890	COG1473	amidohydrolase
Bt4C1_RS17900	COG1131	(ABC) transporter
Bt4C1_RS17920	COG0583	DNA-binding transcription factor activity
Bt4C1_RS17930	COG1346	cytolysis
Bt4C1_RS17945	COG0730	response to heat
Bt4C1_RS17970	COG1132	(ABC) transporter
Bt4C1_RS17975	COG1132	(ABC) transporter
Bt4C1_RS18010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bt4C1_RS18015	COG0737	Belongs to the 5'-nucleotidase family
Bt4C1_RS18025	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Bt4C1_RS18045	COG1695	Transcriptional regulator
Bt4C1_RS18055	COG1196	nuclear chromosome segregation
Bt4C1_RS18055	COG0739	heme binding
Bt4C1_RS18055	COG0741	lytic transglycosylase activity
Bt4C1_RS18060	COG0741	lytic transglycosylase activity
Bt4C1_RS18090	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Bt4C1_RS18095	COG0174	glutamine synthetase
Bt4C1_RS18100	COG0789	Transcriptional regulator
Bt4C1_RS18105	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Bt4C1_RS18110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Bt4C1_RS18115	COG2860	membrane
Bt4C1_RS18125	COG0464	growth
Bt4C1_RS18155	COG3584	3D domain protein
Bt4C1_RS18155	COG1388	LysM domain
Bt4C1_RS18160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bt4C1_RS18160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Bt4C1_RS18160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Bt4C1_RS18165	COG1105	Belongs to the carbohydrate kinase PfkB family
Bt4C1_RS18170	COG1349	DNA-binding transcription factor activity
Bt4C1_RS18175	COG1979	alcohol dehydrogenase
Bt4C1_RS18180	COG2322	membrane
Bt4C1_RS18195	COG1113	amino acid transport
Bt4C1_RS18210	COG1408	metallophosphoesterase
Bt4C1_RS18230	COG2217	Heavy metal translocating P-type atpase
Bt4C1_RS18235	COG2608	mercury ion transmembrane transporter activity
Bt4C1_RS18240	COG1937	Protein conserved in bacteria
Bt4C1_RS18260	COG2819	hydrolase of the alpha beta superfamily
Bt4C1_RS18265	COG1120	ATPase activity
Bt4C1_RS18270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_RS18275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_RS18280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bt4C1_RS18285	COG0708	Exodeoxyribonuclease III
Bt4C1_RS18290	COG2169	Transcriptional regulator
Bt4C1_RS18295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Bt4C1_RS18300	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Bt4C1_RS18310	COG2364	Membrane
Bt4C1_RS18325	COG2267	carboxylic ester hydrolase activity
Bt4C1_RS18330	COG3300	MHYT domain
Bt4C1_RS18330	COG5001	Diguanylate cyclase
Bt4C1_RS18365	COG1346	cytolysis
Bt4C1_RS18375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_RS18390	COG0840	transmembrane signaling receptor activity
Bt4C1_RS18400	COG1404	Belongs to the peptidase S8 family
Bt4C1_RS18405	COG3773	Cell wall hydrolase
Bt4C1_RS18415	COG1368	sulfuric ester hydrolase activity
Bt4C1_RS18420	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Bt4C1_RS18445	COG4550	Control of competence regulator ComK, YlbF/YmcA
Bt4C1_RS18455	COG1013	pyruvate-flavodoxin oxidoreductase activity
Bt4C1_RS18460	COG0674	pyruvate-flavodoxin oxidoreductase activity
Bt4C1_RS18460	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Bt4C1_RS18470	COG2359	stage V sporulation protein S
Bt4C1_RS18475	COG1692	metallophosphoesterase
Bt4C1_RS18500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Bt4C1_RS18505	COG1426	Protein conserved in bacteria
Bt4C1_RS18520	COG0300	oxidoreductase activity
Bt4C1_RS18525	COG0612	Peptidase, M16
Bt4C1_RS18530	COG0612	Peptidase, M16
Bt4C1_RS18535	COG1079	Belongs to the binding-protein-dependent transport system permease family
Bt4C1_RS18540	COG4603	Belongs to the binding-protein-dependent transport system permease family
Bt4C1_RS18545	COG3845	ABC transporter
Bt4C1_RS18550	COG1744	ABC transporter substrate-binding protein PnrA-like
Bt4C1_RS18555	COG2188	Transcriptional regulator
Bt4C1_RS18570	COG0740	serine-type endopeptidase activity
Bt4C1_RS18575	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Bt4C1_RS18585	COG0527	aspartate kinase activity
Bt4C1_RS18590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Bt4C1_RS18595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Bt4C1_RS18600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Bt4C1_RS18605	COG1873	PFAM PRC-barrel domain
Bt4C1_RS18610	COG0612	Peptidase, M16
Bt4C1_RS18615	COG0726	polysaccharide deacetylase
Bt4C1_RS18630	COG0196	riboflavin kinase activity
Bt4C1_RS18640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Bt4C1_RS18645	COG1550	Protein conserved in bacteria
Bt4C1_RS18655	COG1358	cellular component organization or biogenesis
Bt4C1_RS18660	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Bt4C1_RS18665	COG0195	Participates in both transcription termination and antitermination
Bt4C1_RS18685	COG0750	zinc metalloprotease
Bt4C1_RS18695	COG4589	Belongs to the CDS family
Bt4C1_RS18740	COG4974	Belongs to the 'phage' integrase family
Bt4C1_RS18750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Bt4C1_RS18755	COG0758	DNA mediated transformation
Bt4C1_RS18760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Bt4C1_RS18800	COG1837	Belongs to the UPF0109 family
Bt4C1_RS18810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Bt4C1_RS18820	COG0552	protein localization to endoplasmic reticulum
Bt4C1_RS18825	COG1196	nuclear chromosome segregation
Bt4C1_RS18835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Bt4C1_RS18840	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS18845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Bt4C1_RS18860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Bt4C1_RS18865	COG1461	Dihydroxyacetone kinase
Bt4C1_RS18870	COG1302	Protein conserved in bacteria
Bt4C1_RS18885	COG1564	THIamine pyrophosphokinase
Bt4C1_RS18890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Bt4C1_RS18900	COG2815	serine threonine protein kinase
Bt4C1_RS18900	COG0515	serine threonine protein kinase
Bt4C1_RS18905	COG0631	protein serine/threonine phosphatase activity
Bt4C1_RS18915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Bt4C1_RS18915	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Bt4C1_RS18930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Bt4C1_RS18935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Bt4C1_RS18955	COG1561	YicC-like family, N-terminal region
Bt4C1_RS18960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Bt4C1_RS18995	COG3069	C4-dicarboxylate transmembrane transporter activity
Bt4C1_RS19055	COG0564	pseudouridine synthase activity
Bt4C1_RS19075	COG3599	regulation of cell shape
Bt4C1_RS19080	COG2302	S4 RNA-binding domain
Bt4C1_RS19085	COG0762	integral membrane protein
Bt4C1_RS19095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Bt4C1_RS19105	COG1873	PFAM PRC-barrel domain
Bt4C1_RS19110	COG1191	sigma factor activity
Bt4C1_RS19115	COG1191	sigma factor activity
Bt4C1_RS19125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Bt4C1_RS19130	COG0849	cell division
Bt4C1_RS19150	COG0772	Belongs to the SEDS family
Bt4C1_RS19170	COG0768	penicillin binding
Bt4C1_RS19175	COG0768	penicillin binding
Bt4C1_RS19195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Bt4C1_RS19210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Bt4C1_RS19215	COG1399	metal-binding, possibly nucleic acid-binding protein
Bt4C1_RS19225	COG3480	Lon protease (S16) C-terminal proteolytic domain
Bt4C1_RS19230	COG1752	Esterase of the alpha-beta hydrolase superfamily
Bt4C1_RS19235	COG3314	Sporulation integral membrane protein YlbJ
Bt4C1_RS19245	COG0742	ribosomal rna small subunit methyltransferase
Bt4C1_RS19260	COG3679	Belongs to the UPF0342 family
Bt4C1_RS19265	COG0406	alpha-ribazole phosphatase activity
Bt4C1_RS19280	COG2340	Cysteine-rich secretory protein family
Bt4C1_RS19295	COG3336	cytochrome c oxidase
Bt4C1_RS19330	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Bt4C1_RS19335	COG0772	Belongs to the SEDS family
Bt4C1_RS19345	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Bt4C1_RS19350	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Bt4C1_RS19360	COG4896	Protein conserved in bacteria
Bt4C1_RS19375	COG1217	gtp-binding protein TYPA
Bt4C1_RS19385	COG0483	inositol monophosphate 1-phosphatase activity
Bt4C1_RS19405	COG1982	Orn Lys Arg decarboxylase major
Bt4C1_RS19455	COG0022	dehydrogenase e1 component
Bt4C1_RS19460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Bt4C1_RS19475	COG0561	phosphatase activity
Bt4C1_RS19485	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Bt4C1_RS19490	COG0569	domain protein
Bt4C1_RS19510	COG0583	DNA-binding transcription factor activity
Bt4C1_RS19515	COG0517	IMP dehydrogenase activity
Bt4C1_RS19525	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Bt4C1_RS19535	COG4703	Protein of unknown function (DUF1797)
Bt4C1_RS19550	COG2200	EAL domain
Bt4C1_RS19555	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS19560	COG1408	metallophosphoesterase
Bt4C1_RS19605	COG2814	Major facilitator Superfamily
Bt4C1_RS19625	COG3209	COG3209 Rhs family protein
Bt4C1_RS19635	COG2205	protein histidine kinase activity
Bt4C1_RS19645	COG0436	Aminotransferase
Bt4C1_RS19650	COG1609	Transcriptional regulator
Bt4C1_RS19655	COG3833	ABC-type maltose transport systems, permease component
Bt4C1_RS19660	COG1175	transmembrane transport
Bt4C1_RS19665	COG2182	Extracellular solute-binding protein
Bt4C1_RS19675	COG0366	Alpha amylase catalytic
Bt4C1_RS19680	COG3842	ATPase activity
Bt4C1_RS19720	COG0183	Belongs to the thiolase family
Bt4C1_RS19750	COG1695	Transcriptional regulator
Bt4C1_RS19755	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS19775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Bt4C1_RS19780	COG0436	Aminotransferase
Bt4C1_RS19815	COG2084	Dehydrogenase
Bt4C1_RS19825	COG2199	diguanylate cyclase activity
Bt4C1_RS19830	COG0778	Nitroreductase
Bt4C1_RS19855	COG2190	(PTS) system
Bt4C1_RS19855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bt4C1_RS19855	COG1263	PTS System
Bt4C1_RS19860	COG3711	transcriptional antiterminator
Bt4C1_RS19870	COG2188	Transcriptional regulator
Bt4C1_RS19880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Bt4C1_RS19905	COG1547	Domain of unknown function (DUF309)
Bt4C1_RS19910	COG0456	acetyltransferase
Bt4C1_RS19915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Bt4C1_RS19920	COG4086	secreted protein
Bt4C1_RS19925	COG0561	phosphatase activity
Bt4C1_RS19930	COG0697	spore germination
Bt4C1_RS19945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Bt4C1_RS19970	COG0733	neurotransmitter:sodium symporter activity
Bt4C1_RS19990	COG1686	Belongs to the peptidase S11 family
Bt4C1_RS19995	COG1725	Transcriptional regulator
Bt4C1_RS20000	COG1131	(ABC) transporter
Bt4C1_RS20020	COG1846	Transcriptional regulator
Bt4C1_RS20035	COG0598	Magnesium transport protein CorA
Bt4C1_RS20060	COG4974	Belongs to the 'phage' integrase family
Bt4C1_RS20070	COG0735	belongs to the Fur family
Bt4C1_RS20075	COG1300	Membrane
Bt4C1_RS20095	COG0667	Aldo Keto reductase
Bt4C1_RS20100	COG0656	L-ascorbic acid biosynthetic process
Bt4C1_RS20105	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Bt4C1_RS20105	COG0456	acetyltransferase
Bt4C1_RS20115	COG4085	toxin activity
Bt4C1_RS20115	COG0737	Belongs to the 5'-nucleotidase family
Bt4C1_RS20115	COG1525	nuclease
Bt4C1_RS20125	COG0596	Alpha beta hydrolase
Bt4C1_RS20130	COG2056	Na+-H+ antiporter family
Bt4C1_RS20135	COG1609	Transcriptional regulator
Bt4C1_RS20140	COG0456	acetyltransferase
Bt4C1_RS20145	COG1073	alpha beta
Bt4C1_RS20160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Bt4C1_RS20160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Bt4C1_RS20165	COG0307	riboflavin synthase, alpha
Bt4C1_RS20195	COG1073	alpha beta
Bt4C1_RS20195	COG2226	methyltransferase
Bt4C1_RS20210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Bt4C1_RS20220	COG1757	Na H antiporter
Bt4C1_RS20225	COG0737	Belongs to the 5'-nucleotidase family
Bt4C1_RS20235	COG1522	sequence-specific DNA binding
Bt4C1_RS20280	COG0300	oxidoreductase activity
Bt4C1_RS20285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_RS20290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bt4C1_RS20295	COG1760	l-serine dehydratase
Bt4C1_RS20300	COG1760	l-serine dehydratase
Bt4C1_RS20325	COG1285	pathogenesis
Bt4C1_RS20335	COG2195	Cleaves the N-terminal amino acid of tripeptides
Bt4C1_RS20340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_RS20350	COG1376	ErfK ybiS ycfS ynhG family protein
Bt4C1_RS20355	COG4129	membrane
Bt4C1_RS20360	COG1126	abc transporter atp-binding protein
Bt4C1_RS20365	COG0765	amino acid transport
Bt4C1_RS20370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bt4C1_RS20390	COG2323	membrane
Bt4C1_RS20395	COG0772	Belongs to the SEDS family
Bt4C1_RS20400	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bt4C1_RS20405	COG0022	dehydrogenase e1 component
Bt4C1_RS20410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Bt4C1_RS20415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Bt4C1_RS20430	COG0280	phosphate acetyltransferase
Bt4C1_RS20440	COG3829	transcription factor binding
Bt4C1_RS20440	COG3290	protein histidine kinase activity
Bt4C1_RS20450	COG0584	glycerophosphoryl diester phosphodiesterase
Bt4C1_RS20455	COG3093	addiction module antidote protein HigA
Bt4C1_RS20470	COG0750	zinc metalloprotease
Bt4C1_RS20475	COG0497	DNA recombination
Bt4C1_RS20485	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Bt4C1_RS20495	COG0142	geranyltranstransferase activity
Bt4C1_RS20520	COG1302	Protein conserved in bacteria
Bt4C1_RS20525	COG0439	Biotin carboxylase
Bt4C1_RS20530	COG0511	ligase activity, forming carbon-carbon bonds
Bt4C1_RS20570	COG3854	ATPases associated with a variety of cellular activities
Bt4C1_RS20595	COG0006	proline dipeptidase activity
Bt4C1_RS20610	COG3872	metal-dependent enzyme
Bt4C1_RS20620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Bt4C1_RS20655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bt4C1_RS20665	COG1609	Transcriptional regulator
Bt4C1_RS20675	COG2076	Multidrug Resistance protein
Bt4C1_RS20680	COG2076	Multidrug Resistance protein
Bt4C1_RS20710	COG1131	(ABC) transporter
Bt4C1_RS20715	COG1725	Transcriptional regulator
Bt4C1_RS20745	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Bt4C1_RS20775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Bt4C1_RS20810	COG1459	type II secretion system
Bt4C1_RS20815	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Bt4C1_RS20870	COG1410	methionine synthase
Bt4C1_RS20870	COG0646	methionine synthase
Bt4C1_RS20875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Bt4C1_RS20875	COG0646	methionine synthase
Bt4C1_RS20880	COG0626	cystathionine gamma-synthase activity
Bt4C1_RS20885	COG0626	cystathionine gamma-synthase activity
Bt4C1_RS20905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_RS20910	COG1940	carbohydrate kinase activity
Bt4C1_RS20915	COG4483	Protein conserved in bacteria
Bt4C1_RS20920	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Bt4C1_RS20925	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Bt4C1_RS20930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Bt4C1_RS20935	COG0704	Plays a role in the regulation of phosphate uptake
Bt4C1_RS20945	COG0573	inorganic phosphate transmembrane transporter activity
Bt4C1_RS20950	COG0573	inorganic phosphate transmembrane transporter activity
Bt4C1_RS20960	COG0768	penicillin binding
Bt4C1_RS20965	COG0477	Major facilitator Superfamily
Bt4C1_RS20970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Bt4C1_RS20980	COG5521	maltodextrose utilization protein MalA
Bt4C1_RS20995	COG0735	belongs to the Fur family
Bt4C1_RS21000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Bt4C1_RS21005	COG1121	(ABC) transporter
Bt4C1_RS21010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_RS21040	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Bt4C1_RS21045	COG2384	SAM-dependent methyltransferase
Bt4C1_RS21055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Bt4C1_RS21060	COG0358	DNA primase activity
Bt4C1_RS21070	COG0517	IMP dehydrogenase activity
Bt4C1_RS21085	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Bt4C1_RS21090	COG0295	cytidine deaminase activity
Bt4C1_RS21095	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Bt4C1_RS21105	COG1480	7TM receptor with intracellular HD hydrolase
Bt4C1_RS21110	COG1702	phosphate starvation-inducible protein PhoH
Bt4C1_RS21125	COG1610	YqeY-like protein
Bt4C1_RS21130	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Bt4C1_RS21135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Bt4C1_RS21140	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Bt4C1_RS21170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Bt4C1_RS21175	COG1733	regulation of RNA biosynthetic process
Bt4C1_RS21200	COG1466	dna polymerase III delta subunit
Bt4C1_RS21210	COG2333	competence protein COMEC
Bt4C1_RS21210	COG0658	competence protein
Bt4C1_RS21215	COG2131	deaminase
Bt4C1_RS21220	COG1555	photosystem II stabilization
Bt4C1_RS21220	COG1596	polysaccharide export
Bt4C1_RS21225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bt4C1_RS21230	COG2226	methyltransferase
Bt4C1_RS21235	COG0799	negative regulation of ribosome biogenesis
Bt4C1_RS21240	COG1713	HD superfamily hydrolase involved in NAD metabolism
Bt4C1_RS21250	COG1534	Rna-binding protein
Bt4C1_RS21260	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Bt4C1_RS21265	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Bt4C1_RS21290	COG1595	DNA-templated transcription, initiation
Bt4C1_RS21300	COG0778	Nitroreductase
Bt4C1_RS21305	COG2357	RelA SpoT domain protein
Bt4C1_RS21315	COG1785	Belongs to the alkaline phosphatase family
Bt4C1_RS21325	COG2267	carboxylic ester hydrolase activity
Bt4C1_RS21360	COG1404	Belongs to the peptidase S8 family
Bt4C1_RS21365	COG3186	Phenylalanine-4-hydroxylase
Bt4C1_RS21375	COG2514	catechol 2,3-dioxygenase activity
Bt4C1_RS21380	COG2259	Doxx family
Bt4C1_RS21420	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Bt4C1_RS21430	COG1454	alcohol dehydrogenase
Bt4C1_RS21430	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_RS21435	COG0626	cystathionine gamma-synthase activity
Bt4C1_RS21440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Bt4C1_RS21465	COG0768	penicillin binding
Bt4C1_RS21485	COG0826	peptidase U32
Bt4C1_RS21490	COG0826	peptidase U32
Bt4C1_RS21495	COG4122	O-methyltransferase activity
Bt4C1_RS21500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Bt4C1_RS21515	COG4472	Bacterial protein of unknown function (DUF965)
Bt4C1_RS21530	COG0628	permease
Bt4C1_RS21550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Bt4C1_RS21565	COG1104	cysteine desulfurase activity
Bt4C1_RS21570	COG1959	2 iron, 2 sulfur cluster binding
Bt4C1_RS21575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Bt4C1_RS21585	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Bt4C1_RS21615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Bt4C1_RS21625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Bt4C1_RS21625	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Bt4C1_RS21630	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Bt4C1_RS21635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bt4C1_RS21635	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bt4C1_RS21645	COG2244	polysaccharide biosynthetic process
Bt4C1_RS21650	COG2323	membrane
Bt4C1_RS21660	COG1862	Preprotein translocase
Bt4C1_RS21690	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Bt4C1_RS21720	COG0157	Belongs to the NadC ModD family
Bt4C1_RS21725	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Bt4C1_RS21730	COG1104	cysteine desulfurase activity
Bt4C1_RS21735	COG1827	regulation of RNA biosynthetic process
Bt4C1_RS21740	COG2258	MOSC domain
Bt4C1_RS21750	COG0077	Prephenate dehydratase
Bt4C1_RS21755	COG0577	efflux transmembrane transporter activity
Bt4C1_RS21760	COG0577	efflux transmembrane transporter activity
Bt4C1_RS21765	COG1136	(ABC) transporter
Bt4C1_RS21770	COG5002	protein histidine kinase activity
Bt4C1_RS21775	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS21785	COG3290	protein histidine kinase activity
Bt4C1_RS21795	COG2868	ribosomal protein
Bt4C1_RS21805	COG1530	ribonuclease E activity
Bt4C1_RS21810	COG1994	Peptidase M50
Bt4C1_RS21815	COG0739	heme binding
Bt4C1_RS21820	COG2894	cell division
Bt4C1_RS21840	COG1077	Cell shape determining protein MreB Mrl
Bt4C1_RS21860	COG0285	dihydrofolate synthase activity
Bt4C1_RS21875	COG1388	LysM domain
Bt4C1_RS21885	COG0113	porphobilinogen synthase activity
Bt4C1_RS21890	COG1587	Uroporphyrinogen-III synthase
Bt4C1_RS21900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Bt4C1_RS21910	COG1846	Transcriptional regulator
Bt4C1_RS21915	COG1764	response to oxidative stress
Bt4C1_RS21930	COG0470	DNA polymerase III
Bt4C1_RS21930	COG1067	ATP-dependent peptidase activity
Bt4C1_RS21955	COG2801	Transposase and inactivated derivatives
Bt4C1_RS22045	COG0622	Phosphoesterase
Bt4C1_RS22060	COG5401	PFAM Sporulation and spore germination
Bt4C1_RS22080	COG1309	transcriptional regulator
Bt4C1_RS22090	COG2197	response regulator
Bt4C1_RS22095	COG2233	PERMEase
Bt4C1_RS22100	COG0402	S-adenosylhomocysteine deaminase activity
Bt4C1_RS22105	COG1983	PspC domain protein
Bt4C1_RS22110	COG1396	sequence-specific DNA binding
Bt4C1_RS22115	COG0697	spore germination
Bt4C1_RS22125	COG1959	2 iron, 2 sulfur cluster binding
Bt4C1_RS22130	COG1668	transmembrane transport
Bt4C1_RS22135	COG4152	abc transporter atp-binding protein
Bt4C1_RS22140	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
Bt4C1_RS22145	COG1360	Flagellar Motor Protein
Bt4C1_RS22150	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Bt4C1_RS22155	COG1876	peptidase activity
Bt4C1_RS22160	COG0824	Thioesterase
Bt4C1_RS22165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Bt4C1_RS22170	COG1053	succinate dehydrogenase
Bt4C1_RS22175	COG2009	succinate dehydrogenase
Bt4C1_RS22180	COG1719	4-vinyl reductase, 4VR
Bt4C1_RS22190	COG3118	belongs to the thioredoxin family
Bt4C1_RS22195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Bt4C1_RS22200	COG2086	electron transfer activity
Bt4C1_RS22205	COG1024	Enoyl-CoA hydratase
Bt4C1_RS22210	COG1309	transcriptional regulator
Bt4C1_RS22215	COG0318	PFAM AMP-dependent synthetase and ligase
Bt4C1_RS22240	COG2318	DinB family
Bt4C1_RS22255	COG1131	(ABC) transporter
Bt4C1_RS22260	COG2205	protein histidine kinase activity
Bt4C1_RS22265	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS22275	COG4895	conserved protein (DUF2196)
Bt4C1_RS22280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Bt4C1_RS22290	COG4509	Sortase family
Bt4C1_RS22295	COG1120	ATPase activity
Bt4C1_RS22310	COG5386	Cell surface protein
Bt4C1_RS22320	COG5386	Cell surface protein
Bt4C1_RS22325	COG1114	Component of the transport system for branched-chain amino acids
Bt4C1_RS22330	COG1187	pseudouridine synthase activity
Bt4C1_RS22340	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Bt4C1_RS22340	COG1796	DNA polymerase
Bt4C1_RS22345	COG1286	toxin biosynthetic process
Bt4C1_RS22385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Bt4C1_RS22395	COG1418	mRNA catabolic process
Bt4C1_RS22410	COG2814	Major facilitator Superfamily
Bt4C1_RS22415	COG1566	PFAM secretion protein HlyD family protein
Bt4C1_RS22420	COG1309	transcriptional regulator
Bt4C1_RS22425	COG1363	Peptidase, m42
Bt4C1_RS22450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Bt4C1_RS22465	COG1484	DNA-dependent DNA replication
Bt4C1_RS22470	COG3611	Membrane attachment protein
Bt4C1_RS22480	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Bt4C1_RS22485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Bt4C1_RS22490	COG0237	dephospho-CoA kinase activity
Bt4C1_RS22495	COG1971	Probably functions as a manganese efflux pump
Bt4C1_RS22505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bt4C1_RS22505	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bt4C1_RS22510	COG5002	protein histidine kinase activity
Bt4C1_RS22515	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS22535	COG0538	isocitrate dehydrogenase activity
Bt4C1_RS22540	COG0372	Belongs to the citrate synthase family
Bt4C1_RS22550	COG0628	permease
Bt4C1_RS22555	COG3030	protein affecting phage T7 exclusion by the F plasmid
Bt4C1_RS22580	COG1725	Transcriptional regulator
Bt4C1_RS22590	COG0587	DNA-directed DNA polymerase activity
Bt4C1_RS22605	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Bt4C1_RS22620	COG4109	DRTGG domain
Bt4C1_RS22635	COG0006	proline dipeptidase activity
Bt4C1_RS22670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_RS22675	COG0662	Cupin 2, conserved barrel domain protein
Bt4C1_RS22685	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_RS22690	COG0589	response to stress
Bt4C1_RS22730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_RS22755	COG0827	DNA restriction-modification system
Bt4C1_RS22760	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Bt4C1_RS22765	COG3874	Sporulation protein YtfJ
Bt4C1_RS22780	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Bt4C1_RS22790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Bt4C1_RS22805	COG1104	cysteine desulfurase activity
Bt4C1_RS22815	COG0583	DNA-binding transcription factor activity
Bt4C1_RS22820	COG0697	spore germination
Bt4C1_RS22825	COG1309	transcriptional regulator
Bt4C1_RS22830	COG1956	GAF domain-containing protein
Bt4C1_RS22835	COG0626	cystathionine gamma-synthase activity
Bt4C1_RS22870	COG1595	DNA-templated transcription, initiation
Bt4C1_RS22880	COG0110	maltose O-acetyltransferase activity
Bt4C1_RS22885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Bt4C1_RS22890	COG0454	-acetyltransferase
Bt4C1_RS22895	COG0517	IMP dehydrogenase activity
Bt4C1_RS22900	COG0123	including yeast histone deacetylase and acetoin utilization protein
Bt4C1_RS22915	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS22920	COG5002	protein histidine kinase activity
Bt4C1_RS22925	COG0666	response to abiotic stimulus
Bt4C1_RS22960	COG1609	Transcriptional regulator
Bt4C1_RS22965	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Bt4C1_RS22965	COG1605	Chorismate mutase
Bt4C1_RS22970	COG1605	Chorismate mutase
Bt4C1_RS22970	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Bt4C1_RS22975	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Bt4C1_RS22975	COG1605	Chorismate mutase
Bt4C1_RS22980	COG4851	CamS sex pheromone cAM373 precursor
Bt4C1_RS22985	COG3118	belongs to the thioredoxin family
Bt4C1_RS22995	COG2309	aminopeptidase activity
Bt4C1_RS23010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_RS23015	COG0697	spore germination
Bt4C1_RS23020	COG0789	Transcriptional regulator
Bt4C1_RS23035	COG1674	ftsk spoiiie
Bt4C1_RS23050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bt4C1_RS23060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bt4C1_RS23065	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
Bt4C1_RS23070	COG1363	Peptidase, m42
Bt4C1_RS23080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_RS23095	COG0510	thiamine kinase activity
Bt4C1_RS23100	COG1523	belongs to the glycosyl hydrolase 13 family
Bt4C1_RS23110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Bt4C1_RS23115	COG1349	DNA-binding transcription factor activity
Bt4C1_RS23120	COG1187	pseudouridine synthase activity
Bt4C1_RS23125	COG2244	polysaccharide biosynthetic process
Bt4C1_RS23130	COG2081	HI0933 family
Bt4C1_RS23135	COG2814	Major facilitator Superfamily
Bt4C1_RS23145	COG3832	glyoxalase III activity
Bt4C1_RS23165	COG1329	Transcriptional regulator
Bt4C1_RS23190	COG0314	molybdopterin synthase activity
Bt4C1_RS23195	COG1763	Mo-molybdopterin cofactor biosynthetic process
Bt4C1_RS23200	COG0303	'Molybdopterin
Bt4C1_RS23210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bt4C1_RS23215	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Bt4C1_RS23235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bt4C1_RS23245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Bt4C1_RS23285	COG2814	Major facilitator Superfamily
Bt4C1_RS23290	COG0475	glutathione-regulated potassium exporter activity
Bt4C1_RS23295	COG0490	domain, Protein
Bt4C1_RS23300	COG0582	viral genome integration into host DNA
Bt4C1_RS23310	COG1136	(ABC) transporter
Bt4C1_RS23330	COG1242	4 iron, 4 sulfur cluster binding
Bt4C1_RS23335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Bt4C1_RS23340	COG1794	racemase activity, acting on amino acids and derivatives
Bt4C1_RS23355	COG2267	carboxylic ester hydrolase activity
Bt4C1_RS23360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Bt4C1_RS23365	COG0671	phosphoesterase, PA-phosphatase related
Bt4C1_RS23370	COG0438	transferase activity, transferring glycosyl groups
Bt4C1_RS23460	COG5002	protein histidine kinase activity
Bt4C1_RS23465	COG3852	Histidine kinase
Bt4C1_RS23475	COG2267	carboxylic ester hydrolase activity
Bt4C1_RS23480	COG1368	sulfuric ester hydrolase activity
Bt4C1_RS23490	COG4895	conserved protein (DUF2196)
Bt4C1_RS23505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bt4C1_RS23510	COG1116	anion transmembrane transporter activity
Bt4C1_RS23515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bt4C1_RS23540	COG0494	nUDIX hydrolase
Bt4C1_RS23570	COG2076	Multidrug Resistance protein
Bt4C1_RS23575	COG2076	Multidrug Resistance protein
Bt4C1_RS23580	COG0789	Transcriptional regulator
Bt4C1_RS23585	COG1854	S-ribosylhomocysteine lyase activity
Bt4C1_RS23595	COG0288	reversible hydration of carbon dioxide
Bt4C1_RS23605	COG1294	oxidase, subunit
Bt4C1_RS23625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_RS23650	COG1842	Phage shock protein A
Bt4C1_RS23675	COG3859	Proton-coupled thiamine transporter YuaJ
Bt4C1_RS23680	COG5002	protein histidine kinase activity
Bt4C1_RS23685	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS23710	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Bt4C1_RS23715	COG1597	lipid kinase activity
Bt4C1_RS23760	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_RS23770	COG0577	efflux transmembrane transporter activity
Bt4C1_RS23775	COG1136	(ABC) transporter
Bt4C1_RS23780	COG2207	Transcriptional regulator
Bt4C1_RS23780	COG3708	Transcriptional regulator
Bt4C1_RS23790	COG1131	(ABC) transporter
Bt4C1_RS23795	COG5658	integral membrane protein
Bt4C1_RS23800	COG0640	Transcriptional regulator
Bt4C1_RS23810	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS23815	COG2205	protein histidine kinase activity
Bt4C1_RS23820	COG0577	efflux transmembrane transporter activity
Bt4C1_RS23825	COG0577	efflux transmembrane transporter activity
Bt4C1_RS23830	COG1136	(ABC) transporter
Bt4C1_RS23835	COG0577	efflux transmembrane transporter activity
Bt4C1_RS23850	COG2188	Transcriptional regulator
Bt4C1_RS23870	COG3964	amidohydrolase
Bt4C1_RS23890	COG4948	Mandelate Racemase Muconate Lactonizing
Bt4C1_RS23900	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Bt4C1_RS23905	COG0596	Alpha beta hydrolase
Bt4C1_RS23915	COG1169	isochorismate synthase
Bt4C1_RS23920	COG1575	Belongs to the MenA family. Type 1 subfamily
Bt4C1_RS23925	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Bt4C1_RS23930	COG1278	Cold shock
Bt4C1_RS23955	COG0058	SHG alpha-glucan phosphorylase activity
Bt4C1_RS23965	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Bt4C1_RS23970	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Bt4C1_RS23990	COG1309	transcriptional regulator
Bt4C1_RS24135	COG1285	pathogenesis
Bt4C1_RS24140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Bt4C1_RS24155	COG2155	Conserved Protein
Bt4C1_RS24160	COG1098	S1 RNA binding domain
Bt4C1_RS24165	COG0436	Aminotransferase
Bt4C1_RS24170	COG1522	sequence-specific DNA binding
Bt4C1_RS24175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Bt4C1_RS24180	COG2267	carboxylic ester hydrolase activity
Bt4C1_RS24190	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Bt4C1_RS24210	COG5018	Exonuclease
Bt4C1_RS24215	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Bt4C1_RS24235	COG2050	protein possibly involved in aromatic compounds catabolism
Bt4C1_RS24245	COG1268	BioY protein
Bt4C1_RS24250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Bt4C1_RS24255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Bt4C1_RS24270	COG3584	3D domain protein
Bt4C1_RS24285	COG1252	NADH dehydrogenase
Bt4C1_RS24295	COG3708	Transcriptional regulator
Bt4C1_RS24310	COG1683	Conserved Protein
Bt4C1_RS24335	COG0316	Belongs to the HesB IscA family
Bt4C1_RS24350	COG1252	NADH dehydrogenase
Bt4C1_RS24360	COG2274	protein secretion by the type I secretion system
Bt4C1_RS24365	COG0390	transport system, permease component
Bt4C1_RS24370	COG2824	Alkylphosphonate utilization operon protein PhnA
Bt4C1_RS24420	COG4837	Protein of unknown function (DUF1462)
Bt4C1_RS24425	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Bt4C1_RS24435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Bt4C1_RS24440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Bt4C1_RS24460	COG1358	cellular component organization or biogenesis
Bt4C1_RS24470	COG2249	NAD(P)H dehydrogenase (quinone) activity
Bt4C1_RS24475	COG0647	UMP catabolic process
Bt4C1_RS24485	COG2445	Protein of unknown function DUF86
Bt4C1_RS24490	COG1494	fructose-1,6-bisphosphatase
Bt4C1_RS24505	COG4470	Protein conserved in bacteria
Bt4C1_RS24515	COG0789	Transcriptional regulator
Bt4C1_RS24520	COG4377	Putative membrane peptidase family (DUF2324)
Bt4C1_RS24545	COG0739	heme binding
Bt4C1_RS24555	COG3377	Domain of unknown function (DUF1805)
Bt4C1_RS24560	COG0737	Belongs to the 5'-nucleotidase family
Bt4C1_RS24565	COG0719	Fe-S assembly protein
Bt4C1_RS24570	COG0822	iron-sulfur transferase activity
Bt4C1_RS24575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Bt4C1_RS24580	COG0719	Fe-S assembly protein
Bt4C1_RS24585	COG0396	ATPase activity
Bt4C1_RS24590	COG1464	Belongs to the NlpA lipoprotein family
Bt4C1_RS24595	COG1464	Belongs to the NlpA lipoprotein family
Bt4C1_RS24600	COG2011	ABC-type metal ion transport system permease component
Bt4C1_RS24615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bt4C1_RS24620	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
Bt4C1_RS24630	COG1393	Belongs to the ArsC family
Bt4C1_RS24665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_RS24670	COG1960	acyl-CoA dehydrogenase activity
Bt4C1_RS24675	COG0183	Belongs to the thiolase family
Bt4C1_RS24680	COG1250	3-hydroxyacyl-CoA dehydrogenase
Bt4C1_RS24680	COG1024	Enoyl-CoA hydratase
Bt4C1_RS24690	COG1686	Belongs to the peptidase S11 family
Bt4C1_RS24705	COG0011	TIGRFAM Protein of
Bt4C1_RS24710	COG0840	transmembrane signaling receptor activity
Bt4C1_RS24725	COG2814	Major facilitator Superfamily
Bt4C1_RS24730	COG0531	amino acid
Bt4C1_RS24755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_RS24785	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_RS24795	COG1376	ErfK ybiS ycfS ynhG family protein
Bt4C1_RS24800	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS24805	COG5002	protein histidine kinase activity
Bt4C1_RS24835	COG0840	transmembrane signaling receptor activity
Bt4C1_RS24840	COG2151	metal-sulfur cluster biosynthetic enzyme
Bt4C1_RS24845	COG3227	Zinc metalloprotease (Elastase)
Bt4C1_RS24865	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_RS24870	COG0475	glutathione-regulated potassium exporter activity
Bt4C1_RS24875	COG0490	domain, Protein
Bt4C1_RS24880	COG1115	amino acid carrier protein
Bt4C1_RS24885	COG0783	Belongs to the Dps family
Bt4C1_RS24900	COG1611	Belongs to the LOG family
Bt4C1_RS24910	COG1528	Iron-storage protein
Bt4C1_RS24920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_RS24925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_RS24930	COG1115	amino acid carrier protein
Bt4C1_RS24935	COG1115	amino acid carrier protein
Bt4C1_RS24940	COG2910	NAD(P)H-binding
Bt4C1_RS24955	COG0656	L-ascorbic acid biosynthetic process
Bt4C1_RS24960	COG2814	Major facilitator Superfamily
Bt4C1_RS24965	COG1733	regulation of RNA biosynthetic process
Bt4C1_RS24975	COG1252	NADH dehydrogenase
Bt4C1_RS25030	COG0488	(ABC) transporter
Bt4C1_RS25035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_RS25055	COG1335	isochorismatase
Bt4C1_RS25060	COG1522	sequence-specific DNA binding
Bt4C1_RS25070	COG1522	sequence-specific DNA binding
Bt4C1_RS25075	COG0288	reversible hydration of carbon dioxide
Bt4C1_RS25080	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
Bt4C1_RS25085	COG2233	PERMEase
Bt4C1_RS25140	COG0557	exoribonuclease II activity
Bt4C1_RS25145	COG1647	Serine aminopeptidase, S33
Bt4C1_RS25150	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Bt4C1_RS25155	COG1346	cytolysis
Bt4C1_RS25190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Bt4C1_RS25205	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Bt4C1_RS25230	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_RS25450	COG0582	viral genome integration into host DNA
Bt4C1_RS25545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Bt4C1_RS25560	COG2323	membrane
Bt4C1_RS25570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bt4C1_RS25580	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Bt4C1_RS25590	COG1051	belongs to the nudix hydrolase family
Bt4C1_RS25600	COG0492	ferredoxin-NADP+ reductase activity
Bt4C1_RS25605	COG0457	Tetratricopeptide repeat
Bt4C1_RS25610	COG0110	maltose O-acetyltransferase activity
Bt4C1_RS25630	COG1950	PFAM Membrane protein of
Bt4C1_RS25640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Bt4C1_RS25660	COG0789	Transcriptional regulator
Bt4C1_RS25680	COG0583	DNA-binding transcription factor activity
Bt4C1_RS25690	COG0655	NAD(P)H dehydrogenase (quinone) activity
Bt4C1_RS25695	COG0488	(ABC) transporter
Bt4C1_RS25705	COG1132	(ABC) transporter
Bt4C1_RS25710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bt4C1_RS25715	COG3409	Peptidoglycan-binding domain 1 protein
Bt4C1_RS25715	COG0793	Belongs to the peptidase S41A family
Bt4C1_RS25720	COG2177	Part of the ABC transporter FtsEX involved in
Bt4C1_RS25725	COG2884	Cell division ATP-binding protein ftsE
Bt4C1_RS25735	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Bt4C1_RS25745	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Bt4C1_RS25750	COG1278	Cold shock
Bt4C1_RS25755	COG1040	competence protein
Bt4C1_RS25760	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
Bt4C1_RS25780	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_RS25780	COG3409	Peptidoglycan-binding domain 1 protein
Bt4C1_RS25780	COG1388	LysM domain
Bt4C1_RS25785	COG4824	toxin secretion phage lysis holin
Bt4C1_RS25995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Bt4C1_RS26000	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Bt4C1_RS26005	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
Bt4C1_RS26010	COG0791	NLP P60 protein
Bt4C1_RS26015	COG1733	regulation of RNA biosynthetic process
Bt4C1_RS26020	COG1307	EDD domain protein, DegV family
Bt4C1_RS26025	COG1739	Uncharacterized protein family UPF0029
Bt4C1_RS26030	COG1316	TRANSCRIPTIONal
Bt4C1_RS26035	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Bt4C1_RS26040	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Bt4C1_RS26045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Bt4C1_RS26055	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Bt4C1_RS26055	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Bt4C1_RS26075	COG1486	melibiose metabolic process
Bt4C1_RS26080	COG1447	Phosphotransferase system cellobiose-specific component IIA
Bt4C1_RS26085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bt4C1_RS26095	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Bt4C1_RS26105	COG1447	Phosphotransferase system cellobiose-specific component IIA
Bt4C1_RS26115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bt4C1_RS26120	COG1301	dicarboxylic acid transport
Bt4C1_RS26135	COG1511	domain protein
Bt4C1_RS26140	COG0583	DNA-binding transcription factor activity
Bt4C1_RS26155	COG1271	oxidase subunit
Bt4C1_RS26160	COG1294	oxidase, subunit
Bt4C1_RS26165	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Bt4C1_RS26175	COG1620	l-lactate permease
Bt4C1_RS26185	COG2389	metal-binding protein
Bt4C1_RS26195	COG1368	sulfuric ester hydrolase activity
Bt4C1_RS26205	COG1388	LysM domain
Bt4C1_RS26205	COG0791	NLP P60 protein
Bt4C1_RS26210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_RS26220	COG1215	transferase activity, transferring glycosyl groups
Bt4C1_RS26230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bt4C1_RS26235	COG3584	3D domain protein
Bt4C1_RS26235	COG1388	LysM domain
Bt4C1_RS26260	COG4715	Zinc finger, swim domain protein
Bt4C1_RS26265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Bt4C1_RS26305	COG0577	efflux transmembrane transporter activity
Bt4C1_RS26310	COG1136	(ABC) transporter
Bt4C1_RS26335	COG5002	protein histidine kinase activity
Bt4C1_RS26340	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS26350	COG1316	TRANSCRIPTIONal
Bt4C1_RS26360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Bt4C1_RS26365	COG1215	transferase activity, transferring glycosyl groups
Bt4C1_RS26390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Bt4C1_RS26395	COG4464	protein tyrosine phosphatase activity
Bt4C1_RS26400	COG0489	protein tyrosine kinase activity
Bt4C1_RS26405	COG3944	biosynthesis protein
Bt4C1_RS26410	COG0489	protein tyrosine kinase activity
Bt4C1_RS26425	COG1609	Transcriptional regulator
Bt4C1_RS26435	COG0739	heme binding
Bt4C1_RS26450	COG3279	Response regulator of the LytR AlgR family
Bt4C1_RS26455	COG2385	sporulation resulting in formation of a cellular spore
Bt4C1_RS26470	COG4836	Membrane
Bt4C1_RS26475	COG1007	ATP synthesis coupled electron transport
Bt4C1_RS26480	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Bt4C1_RS26485	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Bt4C1_RS26495	COG0839	Belongs to the complex I subunit 6 family
Bt4C1_RS26515	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Bt4C1_RS26530	COG5001	Diguanylate cyclase
Bt4C1_RS26530	COG3300	MHYT domain
Bt4C1_RS26580	COG0356	it plays a direct role in the translocation of protons across the membrane
Bt4C1_RS26610	COG0698	ribose 5-phosphate isomerase
Bt4C1_RS26620	COG2190	(PTS) system
Bt4C1_RS26625	COG2259	Doxx family
Bt4C1_RS26630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Bt4C1_RS26645	COG0009	L-threonylcarbamoyladenylate synthase
Bt4C1_RS26680	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Bt4C1_RS26685	COG1494	fructose-1,6-bisphosphatase
Bt4C1_RS26705	COG4821	SIS domain
Bt4C1_RS26725	COG1960	acyl-CoA dehydrogenase activity
Bt4C1_RS26730	COG1960	acyl-CoA dehydrogenase activity
Bt4C1_RS26735	COG1250	3-hydroxyacyl-CoA dehydrogenase
Bt4C1_RS26740	COG0183	Belongs to the thiolase family
Bt4C1_RS26745	COG0247	lactate metabolic process
Bt4C1_RS26745	COG2181	nitrate reductase activity
Bt4C1_RS26750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bt4C1_RS26760	COG5001	Diguanylate cyclase
Bt4C1_RS26760	COG3300	MHYT domain
Bt4C1_RS26775	COG3227	Zinc metalloprotease (Elastase)
Bt4C1_RS26780	COG2197	response regulator
Bt4C1_RS26785	COG4585	Histidine kinase
Bt4C1_RS26790	COG0842	Transport permease protein
Bt4C1_RS26795	COG1131	(ABC) transporter
Bt4C1_RS26800	COG0024	Methionine aminopeptidase
Bt4C1_RS26810	COG2234	aminopeptidase activity
Bt4C1_RS26830	COG1595	DNA-templated transcription, initiation
Bt4C1_RS26840	COG4506	Protein conserved in bacteria
Bt4C1_RS26845	COG1619	proteins homologs of microcin C7 resistance protein MccF
Bt4C1_RS26870	COG2814	Major facilitator Superfamily
Bt4C1_RS26875	COG0789	Transcriptional regulator
Bt4C1_RS26880	COG0584	glycerophosphoryl diester phosphodiesterase
Bt4C1_RS26885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bt4C1_RS26895	COG1994	Peptidase M50
Bt4C1_RS26905	COG1078	dGTPase activity
Bt4C1_RS26910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bt4C1_RS26915	COG1120	ATPase activity
Bt4C1_RS26920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_RS26925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_RS26945	COG0280	phosphate acetyltransferase
Bt4C1_RS26960	COG3773	Cell wall hydrolase
Bt4C1_RS26970	COG2363	Small membrane protein
Bt4C1_RS26980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Bt4C1_RS26985	COG2233	PERMEase
Bt4C1_RS26990	COG0561	phosphatase activity
Bt4C1_RS26995	COG2814	Major facilitator Superfamily
Bt4C1_RS27005	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Bt4C1_RS27010	COG1131	(ABC) transporter
Bt4C1_RS27015	COG2755	lipolytic protein G-D-S-L family
Bt4C1_RS27020	COG1609	Transcriptional regulator
Bt4C1_RS27030	COG0460	homoserine dehydrogenase
Bt4C1_RS27040	COG2873	o-acetylhomoserine
Bt4C1_RS27045	COG1011	Hydrolase
Bt4C1_RS27050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bt4C1_RS27060	COG2197	response regulator
Bt4C1_RS27065	COG2203	Gaf domain
Bt4C1_RS27065	COG4585	Histidine kinase
Bt4C1_RS27070	COG0351	phosphomethylpyrimidine kinase
Bt4C1_RS27075	COG3706	GGDEF domain
Bt4C1_RS27080	COG2879	small protein
Bt4C1_RS27085	COG1966	Carbon starvation protein
Bt4C1_RS27090	COG3279	Response regulator of the LytR AlgR family
Bt4C1_RS27095	COG0477	Major facilitator Superfamily
Bt4C1_RS27105	COG0438	transferase activity, transferring glycosyl groups
Bt4C1_RS27120	COG0840	transmembrane signaling receptor activity
Bt4C1_RS27130	COG1607	acyl-coa hydrolase
Bt4C1_RS27135	COG1216	Glycosyl transferase, family 2
Bt4C1_RS27150	COG1216	Glycosyl transferase, family 2
Bt4C1_RS27160	COG4485	Bacterial membrane protein, YfhO
Bt4C1_RS27165	COG0463	Glycosyl transferase, family 2
Bt4C1_RS27175	COG1309	transcriptional regulator
Bt4C1_RS27180	COG0488	(ABC) transporter
Bt4C1_RS27185	COG1309	transcriptional regulator
Bt4C1_RS27190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Bt4C1_RS27195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bt4C1_RS27195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bt4C1_RS27200	COG0628	permease
Bt4C1_RS27220	COG3275	phosphorelay sensor kinase activity
Bt4C1_RS27225	COG2814	Major facilitator Superfamily
Bt4C1_RS27230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bt4C1_RS27235	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
Bt4C1_RS27260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Bt4C1_RS27265	COG1272	protein, Hemolysin III
Bt4C1_RS27285	COG1164	Oligoendopeptidase f
Bt4C1_RS27300	COG5002	protein histidine kinase activity
Bt4C1_RS27380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bt4C1_RS27385	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Bt4C1_RS27390	COG4853	Protein conserved in bacteria
Bt4C1_RS27400	COG5002	protein histidine kinase activity
Bt4C1_RS27405	COG0745	RESPONSE REGULATOR receiver
Bt4C1_RS27435	COG0305	Participates in initiation and elongation during chromosome replication
Bt4C1_RS27445	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Bt4C1_RS27450	COG4241	membrane
Bt4C1_RS27460	COG0629	single-stranded DNA binding
Bt4C1_RS27470	COG0012	GTP binding
Bt4C1_RS27475	COG4481	Protein conserved in bacteria
Bt4C1_RS27480	COG0668	transmembrane transport
Bt4C1_RS27490	COG1475	DNA binding
Bt4C1_RS27495	COG1192	Involved in chromosome partitioning
Bt4C1_RS27520	COG1847	R3H domain protein
Bt4C1_RS27535	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Bt4C1_RS27545	COG0592	DNA-directed DNA polymerase activity
Bt4C1_RS27550	COG2501	S4 domain
Bt4C1_RS27560	COG0187	DNA topoisomerase II activity
Bt4C1_RS27565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Bt4C1_RS27715	COG0470	DNA polymerase III
Bt4C1_RS27810	COG2244	polysaccharide biosynthetic process
Bt4C1_RS28395	COG0697	spore germination
Bt4C1_RS28460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bt4C1_RS28500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Bt4C1_RS28850	COG0084	hydrolase, TatD family'
Bt4C1_RS28920	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Bt4C1_RS28940	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Bt4C1_RS28965	COG3956	TIGRFAM MazG family protein
Bt4C1_RS28970	COG3956	TIGRFAM MazG family protein
Bt4C1_RS28975	COG3956	TIGRFAM MazG family protein
Bt4C1_RS29070	COG1428	Deoxynucleoside kinase
Bt4C1_RS29265	COG3956	TIGRFAM MazG family protein
Bt4C1_RS29300	COG2208	phosphoserine phosphatase activity
Bt4C1_RS29410	COG0516	GMP reductase activity
Bt4C1_RS29410	COG0517	IMP dehydrogenase activity