locus-tag	class	description
A9498_RS00010	COG0592	DNA-directed DNA polymerase activity
A9498_RS00015	COG2501	S4 domain
A9498_RS00025	COG0187	DNA topoisomerase II activity
A9498_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A9498_RS00065	COG0517	IMP dehydrogenase activity
A9498_RS00065	COG0516	GMP reductase activity
A9498_RS00070	COG1686	Belongs to the peptidase S11 family
A9498_RS00100	COG1428	Deoxynucleoside kinase
A9498_RS00105	COG1428	Deoxynucleoside kinase
A9498_RS00110	COG1335	isochorismatase
A9498_RS00120	COG0590	tRNA wobble adenosine to inosine editing
A9498_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A9498_RS00185	COG1982	Orn Lys Arg decarboxylase major
A9498_RS00195	COG0470	DNA polymerase III
A9498_RS00200	COG1774	PSP1 C-terminal conserved region
A9498_RS00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A9498_RS00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A9498_RS00225	COG2002	toxin-antitoxin pair type II binding
A9498_RS00235	COG0084	hydrolase, TatD family'
A9498_RS00255	COG4466	Protein conserved in bacteria
A9498_RS00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A9498_RS00275	COG0251	oxidation-reduction process
A9498_RS00305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A9498_RS00310	COG2002	toxin-antitoxin pair type II binding
A9498_RS00315	COG2244	polysaccharide biosynthetic process
A9498_RS00320	COG3956	TIGRFAM MazG family protein
A9498_RS00325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A9498_RS00345	COG1098	S1 RNA binding domain
A9498_RS00360	COG2208	phosphoserine phosphatase activity
A9498_RS00370	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A9498_RS00375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A9498_RS00390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A9498_RS00395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A9498_RS00400	COG0512	Glutamine amidotransferase of anthranilate synthase
A9498_RS00405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A9498_RS00410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A9498_RS00415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A9498_RS00420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A9498_RS00425	COG1396	sequence-specific DNA binding
A9498_RS00430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A9498_RS00520	COG3880	PFAM UvrB UvrC protein
A9498_RS00530	COG0542	response to heat
A9498_RS00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A9498_RS00545	COG4956	integral membrane protein (PIN domain superfamily)
A9498_RS00565	COG1045	serine acetyltransferase
A9498_RS00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9498_RS00585	COG3688	RNA-binding protein containing a PIN domain
A9498_RS00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A9498_RS00605	COG0250	Participates in transcription elongation, termination and antitermination
A9498_RS00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A9498_RS00630	COG2813	Specifically methylates the guanine in position
A9498_RS00645	COG1358	cellular component organization or biogenesis
A9498_RS00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A9498_RS00720	COG0255	Belongs to the universal ribosomal protein uL29 family
A9498_RS00780	COG0201	protein transport
A9498_RS00790	COG0024	Methionine aminopeptidase
A9498_RS00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A9498_RS00835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A9498_RS00860	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9498_RS00865	COG0489	protein tyrosine kinase activity
A9498_RS00875	COG2194	sulfuric ester hydrolase activity
A9498_RS00880	COG0726	polysaccharide deacetylase
A9498_RS00960	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A9498_RS00965	COG4856	YbbR-like protein
A9498_RS01000	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS01005	COG2011	ABC-type metal ion transport system permease component
A9498_RS01010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A9498_RS01015	COG1464	Belongs to the NlpA lipoprotein family
A9498_RS01020	COG0604	alcohol dehydrogenase
A9498_RS01030	COG0277	FAD linked oxidase domain protein
A9498_RS01035	COG2271	Major facilitator Superfamily
A9498_RS01045	COG2814	Major facilitator Superfamily
A9498_RS01060	COG2207	Transcriptional regulator
A9498_RS01075	COG4166	transmembrane transport
A9498_RS01080	COG4166	transmembrane transport
A9498_RS01085	COG0656	L-ascorbic acid biosynthetic process
A9498_RS01105	COG4149	molybdate abc transporter
A9498_RS01110	COG0725	ABC transporter, periplasmic molybdate-binding protein
A9498_RS01115	COG1910	domain protein
A9498_RS01130	COG0697	spore germination
A9498_RS01145	COG0204	Acyl-transferase
A9498_RS01155	COG1609	Transcriptional regulator
A9498_RS01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9498_RS01185	COG5298	Protein conserved in bacteria
A9498_RS01205	COG0488	(ABC) transporter
A9498_RS01215	COG0747	negative chemotaxis
A9498_RS01220	COG0601	transmembrane transport
A9498_RS01225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9498_RS01230	COG0444	Belongs to the ABC transporter superfamily
A9498_RS01235	COG4608	Belongs to the ABC transporter superfamily
A9498_RS01240	COG0561	phosphatase activity
A9498_RS01270	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A9498_RS01275	COG0179	Fumarylacetoacetate (FAA) hydrolase
A9498_RS01285	COG0531	amino acid
A9498_RS01290	COG2814	Major facilitator Superfamily
A9498_RS01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A9498_RS01320	COG4294	response to UV
A9498_RS01325	COG0705	Rhomboid family
A9498_RS01335	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A9498_RS01340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A9498_RS01345	COG0864	Transcriptional regulator
A9498_RS01350	COG2337	Toxic component of a toxin-antitoxin (TA) module
A9498_RS01355	COG2183	response to ionizing radiation
A9498_RS01455	COG0802	atpase or kinase
A9498_RS01460	COG1214	PFAM Peptidase M22, glycoprotease
A9498_RS01465	COG0456	acetyltransferase
A9498_RS01475	COG0488	(ABC) transporter
A9498_RS01490	COG1266	CAAX protease self-immunity
A9498_RS01505	COG0582	viral genome integration into host DNA
A9498_RS01620	COG2946	Replication initiation factor
A9498_RS01635	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A9498_RS01645	COG2252	PERMEase
A9498_RS01655	COG5002	protein histidine kinase activity
A9498_RS01685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A9498_RS01730	COG2205	protein histidine kinase activity
A9498_RS01735	COG0745	RESPONSE REGULATOR receiver
A9498_RS01770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A9498_RS01780	COG0463	Glycosyl transferase, family 2
A9498_RS01780	COG1216	Glycosyl transferase, family 2
A9498_RS01800	COG0697	spore germination
A9498_RS01830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A9498_RS01840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A9498_RS01850	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A9498_RS01865	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A9498_RS01875	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A9498_RS01885	COG0151	Belongs to the GarS family
A9498_RS01915	COG0210	DNA helicase
A9498_RS01925	COG4851	CamS sex pheromone cAM373 precursor
A9498_RS01940	COG1335	isochorismatase
A9498_RS01955	COG2011	ABC-type metal ion transport system permease component
A9498_RS01960	COG1464	Belongs to the NlpA lipoprotein family
A9498_RS01975	COG0003	Pfam Anion-transporting ATPase
A9498_RS01980	COG1846	Transcriptional regulator
A9498_RS01985	COG4682	membrane
A9498_RS02005	COG1597	lipid kinase activity
A9498_RS02015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A9498_RS02025	COG1012	belongs to the aldehyde dehydrogenase family
A9498_RS02030	COG2076	Multidrug Resistance protein
A9498_RS02040	COG2309	aminopeptidase activity
A9498_RS02055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A9498_RS02065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A9498_RS02070	COG4807	Protein conserved in bacteria
A9498_RS02095	COG1757	Na H antiporter
A9498_RS02100	COG1473	amidohydrolase
A9498_RS02115	COG0450	alkyl hydroperoxide reductase
A9498_RS02135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9498_RS02140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9498_RS02145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A9498_RS02155	COG0492	ferredoxin-NADP+ reductase activity
A9498_RS02170	COG0166	Belongs to the GPI family
A9498_RS02215	COG3541	Predicted nucleotidyltransferase
A9498_RS02230	COG2814	Major facilitator Superfamily
A9498_RS02235	COG0723	plastoquinol--plastocyanin reductase activity
A9498_RS02235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9498_RS02245	COG0765	amino acid transport
A9498_RS02250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9498_RS02260	COG0840	transmembrane signaling receptor activity
A9498_RS02285	COG0549	Belongs to the carbamate kinase family
A9498_RS02290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A9498_RS02305	COG0366	Alpha amylase catalytic
A9498_RS02340	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A9498_RS02360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A9498_RS02370	COG1116	anion transmembrane transporter activity
A9498_RS02420	COG2270	Major facilitator Superfamily
A9498_RS02450	COG2310	stress, protein
A9498_RS02455	COG2310	stress, protein
A9498_RS02460	COG2310	stress, protein
A9498_RS02465	COG0861	Integral membrane protein TerC family
A9498_RS02475	COG3853	Toxic anion resistance protein (TelA)
A9498_RS02490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A9498_RS02500	COG1295	ribonuclease BN
A9498_RS02505	COG2217	Heavy metal translocating P-type atpase
A9498_RS02510	COG0697	spore germination
A9498_RS02530	COG0586	Pfam SNARE associated Golgi protein
A9498_RS02545	COG3871	stress protein (general stress protein 26)
A9498_RS02550	COG0387	Pfam Sodium calcium exchanger
A9498_RS02560	COG0535	radical SAM domain protein
A9498_RS02580	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A9498_RS02585	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A9498_RS02600	COG3829	transcription factor binding
A9498_RS02610	COG0833	amino acid
A9498_RS02615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A9498_RS02645	COG1263	PTS System
A9498_RS02645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9498_RS02650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A9498_RS02665	COG0463	Glycosyl transferase, family 2
A9498_RS02675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A9498_RS02675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A9498_RS02695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A9498_RS02715	COG1228	amidohydrolase
A9498_RS02720	COG1090	epimerase
A9498_RS02750	COG1988	membrane-bound metal-dependent
A9498_RS02755	COG1194	a g-specific adenine glycosylase
A9498_RS02785	COG1132	(ABC) transporter
A9498_RS02790	COG4129	membrane
A9498_RS02795	COG0070	glutamate synthase
A9498_RS02795	COG0069	glutamate synthase activity
A9498_RS02795	COG0067	glutamate synthase
A9498_RS02805	COG4555	ABC transporter
A9498_RS02825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A9498_RS02830	COG0735	belongs to the Fur family
A9498_RS02935	COG4974	Belongs to the 'phage' integrase family
A9498_RS03020	COG0457	Tetratricopeptide repeat
A9498_RS03030	COG4974	Belongs to the 'phage' integrase family
A9498_RS03120	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A9498_RS03145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A9498_RS03155	COG2766	serine protein kinase
A9498_RS03175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A9498_RS03185	COG1585	Membrane protein implicated in regulation of membrane protease activity
A9498_RS03200	COG3290	protein histidine kinase activity
A9498_RS03205	COG4565	transcriptional regulatory protein
A9498_RS03210	COG2851	Citrate transporter
A9498_RS03235	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A9498_RS03240	COG3842	ATPase activity
A9498_RS03245	COG1175	transmembrane transport
A9498_RS03345	COG0582	viral genome integration into host DNA
A9498_RS03495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A9498_RS03500	COG0745	RESPONSE REGULATOR receiver
A9498_RS03505	COG3850	Histidine kinase
A9498_RS03505	COG5002	protein histidine kinase activity
A9498_RS03515	COG4990	cell redox homeostasis
A9498_RS03530	COG4565	transcriptional regulatory protein
A9498_RS03535	COG3493	citrate carrier protein
A9498_RS03540	COG0281	malic enzyme
A9498_RS03550	COG0697	spore germination
A9498_RS03555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A9498_RS03565	COG5002	protein histidine kinase activity
A9498_RS03570	COG0745	RESPONSE REGULATOR receiver
A9498_RS03575	COG0454	-acetyltransferase
A9498_RS03575	COG0456	acetyltransferase
A9498_RS03580	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A9498_RS03585	COG3383	formate dehydrogenase (NAD+) activity
A9498_RS03590	COG2427	Protein of unknown function (DUF1641)
A9498_RS03605	COG0531	amino acid
A9498_RS03615	COG0640	Transcriptional regulator
A9498_RS03620	COG2217	Heavy metal translocating P-type atpase
A9498_RS03630	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A9498_RS03645	COG3227	Zinc metalloprotease (Elastase)
A9498_RS03665	COG2720	vancomycin resistance protein
A9498_RS03670	COG1316	TRANSCRIPTIONal
A9498_RS03675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A9498_RS03680	COG0346	lactoylglutathione lyase activity
A9498_RS03685	COG1253	flavin adenine dinucleotide binding
A9498_RS03690	COG1027	Aspartate ammonia-lyase
A9498_RS03695	COG1620	l-lactate permease
A9498_RS03710	COG3104	oligopeptide transport
A9498_RS03715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A9498_RS03720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9498_RS03725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9498_RS03735	COG2226	methyltransferase
A9498_RS03745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A9498_RS03755	COG4548	von Willebrand factor, type A
A9498_RS03760	COG0714	Associated with various cellular activities
A9498_RS03780	COG0531	amino acid
A9498_RS03785	COG2188	Transcriptional regulator
A9498_RS03790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9498_RS03790	COG1263	PTS System
A9498_RS03795	COG0366	Alpha amylase catalytic
A9498_RS03810	COG0697	spore germination
A9498_RS03815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A9498_RS03820	COG1115	amino acid carrier protein
A9498_RS03830	COG1126	abc transporter atp-binding protein
A9498_RS03835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9498_RS03840	COG0765	amino acid transport
A9498_RS03845	COG0765	amino acid transport
A9498_RS03850	COG0833	amino acid
A9498_RS03865	COG1595	DNA-templated transcription, initiation
A9498_RS03875	COG2378	regulation of single-species biofilm formation
A9498_RS03880	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A9498_RS03885	COG5002	protein histidine kinase activity
A9498_RS03915	COG2271	Major facilitator Superfamily
A9498_RS03920	COG1846	Transcriptional regulator
A9498_RS03925	COG0477	Major facilitator Superfamily
A9498_RS03930	COG1609	Transcriptional regulator
A9498_RS03935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A9498_RS03950	COG1172	Belongs to the binding-protein-dependent transport system permease family
A9498_RS03955	COG1879	ABC-type sugar transport system periplasmic component
A9498_RS03985	COG1063	alcohol dehydrogenase
A9498_RS04030	COG1396	sequence-specific DNA binding
A9498_RS04110	COG0582	viral genome integration into host DNA
A9498_RS04160	COG1802	Transcriptional regulator
A9498_RS04160	COG4626	Terminase
A9498_RS04170	COG0740	serine-type endopeptidase activity
A9498_RS04240	COG3409	Peptidoglycan-binding domain 1 protein
A9498_RS04240	COG5632	N-Acetylmuramoyl-L-alanine amidase
A9498_RS04240	COG1388	LysM domain
A9498_RS04310	COG0840	transmembrane signaling receptor activity
A9498_RS04315	COG3584	3D domain protein
A9498_RS04315	COG1388	LysM domain
A9498_RS04320	COG1476	TRANSCRIPTIONal
A9498_RS04340	COG3104	oligopeptide transport
A9498_RS04345	COG1114	Component of the transport system for branched-chain amino acids
A9498_RS04360	COG1113	amino acid transport
A9498_RS04365	COG2252	PERMEase
A9498_RS04380	COG2153	protein acetylation
A9498_RS04390	COG0569	domain protein
A9498_RS04390	COG0475	glutathione-regulated potassium exporter activity
A9498_RS04400	COG1845	cytochrome c oxidase, subunit III
A9498_RS04405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A9498_RS04410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A9498_RS04415	COG0833	amino acid
A9498_RS04420	COG4990	cell redox homeostasis
A9498_RS04435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A9498_RS04440	COG0697	spore germination
A9498_RS04445	COG0531	amino acid
A9498_RS04455	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A9498_RS04460	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A9498_RS04465	COG1918	ferrous iron import across plasma membrane
A9498_RS04465	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A9498_RS04470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A9498_RS04475	COG0573	inorganic phosphate transmembrane transporter activity
A9498_RS04480	COG0581	inorganic phosphate transmembrane transporter activity
A9498_RS04485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9498_RS04605	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A9498_RS04625	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A9498_RS04630	COG1116	anion transmembrane transporter activity
A9498_RS04635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A9498_RS04640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A9498_RS04645	COG0352	thiamine-phosphate diphosphorylase activity
A9498_RS04650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9498_RS04655	COG2104	thiamine diphosphate biosynthetic process
A9498_RS04665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A9498_RS04670	COG0351	phosphomethylpyrimidine kinase
A9498_RS04710	COG2205	protein histidine kinase activity
A9498_RS04715	COG2814	Major facilitator Superfamily
A9498_RS04720	COG1846	Transcriptional regulator
A9498_RS04735	COG2252	PERMEase
A9498_RS04740	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS04755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A9498_RS04760	COG1621	beta-fructofuranosidase activity
A9498_RS04765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9498_RS04765	COG1263	PTS System
A9498_RS04770	COG1609	Transcriptional regulator
A9498_RS04820	COG0778	Nitroreductase
A9498_RS04825	COG2719	SpoVR family
A9498_RS04830	COG0446	pyridine nucleotide-disulphide oxidoreductase
A9498_RS04835	COG1937	Protein conserved in bacteria
A9498_RS04840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9498_RS04840	COG0425	Belongs to the sulfur carrier protein TusA family
A9498_RS04845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9498_RS04845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9498_RS04850	COG0425	Belongs to the sulfur carrier protein TusA family
A9498_RS04855	COG0425	Belongs to the sulfur carrier protein TusA family
A9498_RS04855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9498_RS04865	COG2210	Belongs to the sulfur carrier protein TusA family
A9498_RS04870	COG0730	response to heat
A9498_RS04880	COG1316	TRANSCRIPTIONal
A9498_RS04885	COG0604	alcohol dehydrogenase
A9498_RS04890	COG1283	sodium-dependent phosphate transmembrane transporter activity
A9498_RS04910	COG3711	transcriptional antiterminator
A9498_RS04910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9498_RS04915	COG1447	Phosphotransferase system cellobiose-specific component IIA
A9498_RS04920	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9498_RS04950	COG3584	3D domain protein
A9498_RS04950	COG1388	LysM domain
A9498_RS04955	COG0577	efflux transmembrane transporter activity
A9498_RS04960	COG1136	(ABC) transporter
A9498_RS04970	COG5522	Integral membrane protein (intg_mem_TP0381)
A9498_RS04985	COG1114	Component of the transport system for branched-chain amino acids
A9498_RS04990	COG3546	catalase activity
A9498_RS05025	COG0586	Pfam SNARE associated Golgi protein
A9498_RS05055	COG0531	amino acid
A9498_RS05060	COG0475	glutathione-regulated potassium exporter activity
A9498_RS05070	COG1737	Transcriptional regulator
A9498_RS05080	COG1263	PTS System
A9498_RS05080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9498_RS05090	COG2259	Doxx family
A9498_RS05105	COG0697	spore germination
A9498_RS05110	COG1522	sequence-specific DNA binding
A9498_RS05115	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A9498_RS05115	COG0165	Argininosuccinate lyase
A9498_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS05140	COG1309	transcriptional regulator
A9498_RS05145	COG2814	Major facilitator Superfamily
A9498_RS05180	COG1136	(ABC) transporter
A9498_RS05185	COG0577	efflux transmembrane transporter activity
A9498_RS05190	COG1136	(ABC) transporter
A9498_RS05195	COG0577	efflux transmembrane transporter activity
A9498_RS05210	COG1733	regulation of RNA biosynthetic process
A9498_RS05225	COG4533	DNA binding
A9498_RS05230	COG2211	Major facilitator Superfamily
A9498_RS05240	COG0693	protein deglycase activity
A9498_RS05245	COG0753	catalase activity
A9498_RS05255	COG0531	amino acid
A9498_RS05260	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A9498_RS05270	COG1012	belongs to the aldehyde dehydrogenase family
A9498_RS05285	COG1132	(ABC) transporter
A9498_RS05290	COG1132	(ABC) transporter
A9498_RS05300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9498_RS05305	COG0765	amino acid transport
A9498_RS05310	COG1126	abc transporter atp-binding protein
A9498_RS05325	COG0189	ligase activity
A9498_RS05355	COG0028	Belongs to the TPP enzyme family
A9498_RS05360	COG3527	Alpha-acetolactate decarboxylase
A9498_RS05370	COG0561	phosphatase activity
A9498_RS05380	COG5632	N-Acetylmuramoyl-L-alanine amidase
A9498_RS05380	COG3409	Peptidoglycan-binding domain 1 protein
A9498_RS05385	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A9498_RS05410	COG0659	secondary active sulfate transmembrane transporter activity
A9498_RS05415	COG2244	polysaccharide biosynthetic process
A9498_RS05435	COG1024	Enoyl-CoA hydratase
A9498_RS05455	COG1363	Peptidase, m42
A9498_RS05495	COG0601	transmembrane transport
A9498_RS05500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9498_RS05505	COG0444	Belongs to the ABC transporter superfamily
A9498_RS05510	COG4608	Belongs to the ABC transporter superfamily
A9498_RS05535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9498_RS05670	COG0477	Major facilitator Superfamily
A9498_RS05680	COG4565	transcriptional regulatory protein
A9498_RS05685	COG3181	Tripartite tricarboxylate transporter family receptor
A9498_RS05715	COG0210	DNA helicase
A9498_RS05740	COG0642	Histidine kinase
A9498_RS05755	COG0270	DNA (cytosine-5-)-methyltransferase activity
A9498_RS05765	COG0305	Participates in initiation and elongation during chromosome replication
A9498_RS05790	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A9498_RS05795	COG1288	antiporter activity
A9498_RS05805	COG0477	Major facilitator Superfamily
A9498_RS05825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9498_RS05925	COG2020	methyltransferase activity
A9498_RS05950	COG1073	alpha beta
A9498_RS05970	COG1476	TRANSCRIPTIONal
A9498_RS05985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A9498_RS06035	COG1183	phosphatidylcholine synthase activity
A9498_RS06050	COG2814	Major facilitator Superfamily
A9498_RS06055	COG0640	Transcriptional regulator
A9498_RS06095	COG2373	Large extracellular alpha-helical protein
A9498_RS06170	COG1191	sigma factor activity
A9498_RS06180	COG2208	phosphoserine phosphatase activity
A9498_RS06185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A9498_RS06190	COG5002	protein histidine kinase activity
A9498_RS06190	COG0784	Response regulator, receiver
A9498_RS06190	COG2205	protein histidine kinase activity
A9498_RS06235	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A9498_RS06255	COG0420	3'-5' exonuclease activity
A9498_RS06260	COG4717	serine-type aminopeptidase activity
A9498_RS06270	COG0346	lactoylglutathione lyase activity
A9498_RS06275	COG0346	lactoylglutathione lyase activity
A9498_RS06290	COG2267	carboxylic ester hydrolase activity
A9498_RS06315	COG2140	Oxalate decarboxylase
A9498_RS06320	COG3620	sequence-specific DNA binding
A9498_RS06325	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A9498_RS06330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A9498_RS06340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A9498_RS06345	COG1695	Transcriptional regulator
A9498_RS06355	COG1595	DNA-templated transcription, initiation
A9498_RS06370	COG3973	AAA domain
A9498_RS06400	COG4980	gas vesicle protein
A9498_RS06405	COG0537	adenosine 5'-monophosphoramidase activity
A9498_RS06410	COG1131	(ABC) transporter
A9498_RS06415	COG4473	ABC transporter
A9498_RS06430	COG1309	transcriptional regulator
A9498_RS06435	COG3402	PFAM membrane-flanked domain
A9498_RS06440	COG3428	Bacterial PH domain
A9498_RS06475	COG0697	spore germination
A9498_RS06480	COG3402	PFAM membrane-flanked domain
A9498_RS06485	COG3428	Bacterial PH domain
A9498_RS06490	COG2329	Antibiotic biosynthesis monooxygenase
A9498_RS06495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9498_RS06510	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A9498_RS06545	COG1309	transcriptional regulator
A9498_RS06575	COG1609	Transcriptional regulator
A9498_RS06585	COG1234	tRNA 3'-trailer cleavage
A9498_RS06590	COG0095	Lipoate-protein ligase
A9498_RS06600	COG0318	PFAM AMP-dependent synthetase and ligase
A9498_RS06620	COG4208	sulfate ABC transporter
A9498_RS06640	COG1073	alpha beta
A9498_RS06645	COG1408	metallophosphoesterase
A9498_RS06660	COG1595	DNA-templated transcription, initiation
A9498_RS06670	COG2207	Transcriptional regulator
A9498_RS06670	COG3708	Transcriptional regulator
A9498_RS06680	COG2205	protein histidine kinase activity
A9498_RS06685	COG0745	RESPONSE REGULATOR receiver
A9498_RS06705	COG0501	Belongs to the peptidase M48B family
A9498_RS06710	COG0840	transmembrane signaling receptor activity
A9498_RS06715	COG3693	PFAM glycoside hydrolase, family 10
A9498_RS06725	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A9498_RS06730	COG2224	Isocitrate lyase
A9498_RS06745	COG1278	Cold shock
A9498_RS06770	COG0398	Pfam SNARE associated Golgi protein
A9498_RS06830	COG0179	Fumarylacetoacetate (FAA) hydrolase
A9498_RS06865	COG0753	catalase activity
A9498_RS06870	COG0004	ammonium transporteR
A9498_RS06890	COG2996	Protein conserved in bacteria
A9498_RS06920	COG0561	phosphatase activity
A9498_RS06940	COG2267	carboxylic ester hydrolase activity
A9498_RS06960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A9498_RS06965	COG5504	Zn-dependent protease
A9498_RS06975	COG0180	Tryptophanyl-tRNA synthetase
A9498_RS06990	COG4166	transmembrane transport
A9498_RS06995	COG0601	transmembrane transport
A9498_RS07000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9498_RS07005	COG0444	Belongs to the ABC transporter superfamily
A9498_RS07010	COG4608	Belongs to the ABC transporter superfamily
A9498_RS07015	COG0534	Mate efflux family protein
A9498_RS07020	COG4166	transmembrane transport
A9498_RS07035	COG0861	Integral membrane protein TerC family
A9498_RS07045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9498_RS07055	COG1164	Oligoendopeptidase f
A9498_RS07065	COG2346	COG2346, Truncated hemoglobins
A9498_RS07070	COG4116	CYTH
A9498_RS07080	COG2357	RelA SpoT domain protein
A9498_RS07090	COG0564	pseudouridine synthase activity
A9498_RS07105	COG0772	Belongs to the SEDS family
A9498_RS07110	COG1216	Glycosyl transferase, family 2
A9498_RS07130	COG0463	Glycosyl transferase, family 2
A9498_RS07130	COG0457	Tetratricopeptide repeat
A9498_RS07150	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A9498_RS07165	COG1091	dTDP-4-dehydrorhamnose reductase activity
A9498_RS07210	COG2153	protein acetylation
A9498_RS07220	COG2382	esterase
A9498_RS07245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A9498_RS07260	COG0512	Glutamine amidotransferase of anthranilate synthase
A9498_RS07260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A9498_RS07295	COG1620	l-lactate permease
A9498_RS07300	COG5634	Uncharacterized conserved protein (DUF2278)
A9498_RS07355	COG0508	dehydrogenase complex catalyzes the overall conversion of
A9498_RS07365	COG1476	TRANSCRIPTIONal
A9498_RS07410	COG1686	Belongs to the peptidase S11 family
A9498_RS07415	COG0681	Belongs to the peptidase S26 family
A9498_RS07450	COG1012	belongs to the aldehyde dehydrogenase family
A9498_RS07460	COG1176	ABC-type spermidine putrescine transport system, permease component I
A9498_RS07465	COG1177	transmembrane transport
A9498_RS07480	COG2409	Drug exporters of the RND superfamily
A9498_RS07490	COG0564	pseudouridine synthase activity
A9498_RS07500	COG2340	Cysteine-rich secretory protein family
A9498_RS07505	COG0247	lactate metabolic process
A9498_RS07510	COG0277	FAD linked oxidase domain protein
A9498_RS07515	COG3835	regulator
A9498_RS07525	COG0745	RESPONSE REGULATOR receiver
A9498_RS07530	COG5002	protein histidine kinase activity
A9498_RS07535	COG2186	Transcriptional regulator
A9498_RS07555	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A9498_RS07565	COG2116	formate transmembrane transporter activity
A9498_RS07570	COG0861	Integral membrane protein TerC family
A9498_RS07575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A9498_RS07595	COG2030	dehydratase
A9498_RS07615	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS07620	COG3243	poly(R)-hydroxyalkanoic acid synthase
A9498_RS07630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A9498_RS07645	COG1840	ABC-type Fe3 transport system, periplasmic component
A9498_RS07650	COG3842	ATPase activity
A9498_RS07675	COG1349	DNA-binding transcription factor activity
A9498_RS07685	COG0235	Class ii aldolase
A9498_RS07695	COG2861	carbohydrate metabolic process
A9498_RS07705	COG3852	Histidine kinase
A9498_RS07710	COG1846	Transcriptional regulator
A9498_RS07720	COG2318	DinB family
A9498_RS07725	COG5002	protein histidine kinase activity
A9498_RS07735	COG0720	synthase
A9498_RS07750	COG4873	Protein conserved in bacteria
A9498_RS07780	COG1780	Probably involved in ribonucleotide reductase function
A9498_RS07785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9498_RS07800	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9498_RS07805	COG1725	Transcriptional regulator
A9498_RS07810	COG1131	(ABC) transporter
A9498_RS07820	COG1131	(ABC) transporter
A9498_RS07840	COG1522	sequence-specific DNA binding
A9498_RS07850	COG1335	isochorismatase
A9498_RS07860	COG1619	proteins homologs of microcin C7 resistance protein MccF
A9498_RS07865	COG2070	2-Nitropropane dioxygenase
A9498_RS07870	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A9498_RS07880	COG1696	Membrane protein involved in D-alanine export
A9498_RS07905	COG0716	FMN binding
A9498_RS07950	COG1846	Transcriptional regulator
A9498_RS07960	COG1301	dicarboxylic acid transport
A9498_RS07965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A9498_RS07970	COG4709	membrane
A9498_RS07975	COG3874	Sporulation protein YtfJ
A9498_RS07995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A9498_RS08000	COG0028	Belongs to the TPP enzyme family
A9498_RS08005	COG0440	acetolactate synthase activity
A9498_RS08080	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A9498_RS08095	COG1183	phosphatidylcholine synthase activity
A9498_RS08100	COG1368	sulfuric ester hydrolase activity
A9498_RS08110	COG0019	diaminopimelate decarboxylase activity
A9498_RS08130	COG0529	Catalyzes the synthesis of activated sulfate
A9498_RS08135	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A9498_RS08160	COG0733	neurotransmitter:sodium symporter activity
A9498_RS08180	COG1757	Na H antiporter
A9498_RS08195	COG4758	membrane
A9498_RS08200	COG4585	Histidine kinase
A9498_RS08205	COG2197	response regulator
A9498_RS08215	COG1114	Component of the transport system for branched-chain amino acids
A9498_RS08265	COG0730	response to heat
A9498_RS08270	COG0306	phosphate transporter
A9498_RS08275	COG1392	Phosphate transport regulator
A9498_RS08295	COG3852	Histidine kinase
A9498_RS08300	COG1801	Protein of unknown function DUF72
A9498_RS08310	COG0582	viral genome integration into host DNA
A9498_RS08315	COG5002	protein histidine kinase activity
A9498_RS08335	COG0392	lysyltransferase activity
A9498_RS08335	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A9498_RS08350	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A9498_RS08355	COG1686	Belongs to the peptidase S11 family
A9498_RS08360	COG2715	membrane protein required for spore maturation
A9498_RS08365	COG0700	Nucleoside recognition
A9498_RS08370	COG1187	pseudouridine synthase activity
A9498_RS08380	COG1333	cytochrome c biogenesis protein
A9498_RS08385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A9498_RS08390	COG0745	RESPONSE REGULATOR receiver
A9498_RS08395	COG5002	protein histidine kinase activity
A9498_RS08400	COG2096	Adenosyltransferase
A9498_RS08415	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A9498_RS08420	COG1141	Ferredoxin
A9498_RS08430	COG0514	ATP-dependent DNA helicase (RecQ)
A9498_RS08435	COG1266	CAAX protease self-immunity
A9498_RS08445	COG1408	metallophosphoesterase
A9498_RS08450	COG0789	Transcriptional regulator
A9498_RS08460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A9498_RS08480	COG0492	ferredoxin-NADP+ reductase activity
A9498_RS08485	COG0252	asparaginase activity
A9498_RS08550	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A9498_RS08575	COG0142	geranyltranstransferase activity
A9498_RS08585	COG0142	geranyltranstransferase activity
A9498_RS08610	COG0457	Tetratricopeptide repeat
A9498_RS08630	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A9498_RS08640	COG4347	Protein of unknown function (DUF1405)
A9498_RS08655	COG2738	Putative neutral zinc metallopeptidase
A9498_RS08665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9498_RS08675	COG1694	Mazg nucleotide pyrophosphohydrolase
A9498_RS08695	COG0438	transferase activity, transferring glycosyl groups
A9498_RS08730	COG1199	ATP-dependent helicase activity
A9498_RS08730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A9498_RS08750	COG3935	DnaD domain protein
A9498_RS08755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A9498_RS08820	COG0116	Belongs to the methyltransferase superfamily
A9498_RS08830	COG1199	ATP-dependent helicase activity
A9498_RS08835	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A9498_RS08845	COG0024	Methionine aminopeptidase
A9498_RS08855	COG2233	PERMEase
A9498_RS08860	COG2311	Membrane
A9498_RS08865	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A9498_RS08875	COG0456	acetyltransferase
A9498_RS08925	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9498_RS08940	COG4974	Belongs to the 'phage' integrase family
A9498_RS08970	COG3944	biosynthesis protein
A9498_RS08980	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A9498_RS08995	COG1215	transferase activity, transferring glycosyl groups
A9498_RS09015	COG0454	-acetyltransferase
A9498_RS09035	COG0328	RNA-DNA hybrid ribonuclease activity
A9498_RS09070	COG3403	YqcI/YcgG family
A9498_RS09075	COG1280	lysine exporter protein (LysE YggA)
A9498_RS09095	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A9498_RS09100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A9498_RS09110	COG0475	glutathione-regulated potassium exporter activity
A9498_RS09115	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A9498_RS09125	COG4978	Transcriptional regulator
A9498_RS09125	COG0789	Transcriptional regulator
A9498_RS09135	COG2323	membrane
A9498_RS09140	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A9498_RS09180	COG1923	regulation of RNA biosynthetic process
A9498_RS09195	COG1360	Flagellar Motor Protein
A9498_RS09200	COG2201	protein-glutamate methylesterase activity
A9498_RS09205	COG2198	Histidine kinase
A9498_RS09205	COG0643	Histidine kinase
A9498_RS09210	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A9498_RS09210	COG1776	CheC inhibitor of MCP methylation
A9498_RS09225	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A9498_RS09245	COG1256	bacterial-type flagellum assembly
A9498_RS09250	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A9498_RS09270	COG1815	bacterial-type flagellum-dependent cell motility
A9498_RS09275	COG1558	bacterial-type flagellum-dependent cell motility
A9498_RS09285	COG1766	The M ring may be actively involved in energy transduction
A9498_RS09290	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A9498_RS09300	COG1157	protein secretion by the type III secretion system
A9498_RS09325	COG1749	Flagellar hook protein flgE
A9498_RS09340	COG0835	chemotaxis
A9498_RS09340	COG0784	Response regulator, receiver
A9498_RS09350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A9498_RS09355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A9498_RS09360	COG0741	lytic transglycosylase activity
A9498_RS09370	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A9498_RS09375	COG1776	CheC inhibitor of MCP methylation
A9498_RS09375	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A9498_RS09385	COG1338	Plays a role in the flagellum-specific transport system
A9498_RS09390	COG1987	bacterial-type flagellum assembly
A9498_RS09400	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A9498_RS09405	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A9498_RS09410	COG1419	protein localization to endoplasmic reticulum
A9498_RS09415	COG4786	Flagellar basal body rod
A9498_RS09420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A9498_RS09455	COG2329	Antibiotic biosynthesis monooxygenase
A9498_RS09480	COG0583	DNA-binding transcription factor activity
A9498_RS09485	COG3842	ATPase activity
A9498_RS09490	COG1840	ABC-type Fe3 transport system, periplasmic component
A9498_RS09530	COG0406	alpha-ribazole phosphatase activity
A9498_RS09560	COG0367	asparagine synthase
A9498_RS09590	COG1802	Transcriptional regulator
A9498_RS09595	COG0697	spore germination
A9498_RS09605	COG0523	cobalamin synthesis protein
A9498_RS09615	COG0701	Predicted permease
A9498_RS09630	COG1757	Na H antiporter
A9498_RS09635	COG0789	Transcriptional regulator
A9498_RS09660	COG0534	Mate efflux family protein
A9498_RS09665	COG3340	Belongs to the peptidase S51 family
A9498_RS09685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9498_RS09695	COG0457	Tetratricopeptide repeat
A9498_RS09715	COG2733	membrane
A9498_RS09755	COG1131	(ABC) transporter
A9498_RS09775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9498_RS09780	COG0528	UMP kinase activity
A9498_RS09790	COG1027	Aspartate ammonia-lyase
A9498_RS09795	COG0281	malic enzyme
A9498_RS09805	COG4191	Histidine kinase
A9498_RS09810	COG0784	Response regulator, receiver
A9498_RS09815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A9498_RS09895	COG1695	Transcriptional regulator
A9498_RS09905	COG0477	Major facilitator Superfamily
A9498_RS09915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A9498_RS09920	COG2223	nitrite transmembrane transporter activity
A9498_RS09925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A9498_RS09945	COG0733	neurotransmitter:sodium symporter activity
A9498_RS09950	COG5566	PFAM Mor transcription activator
A9498_RS09955	COG2323	membrane
A9498_RS09975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9498_RS09985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A9498_RS10010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A9498_RS10035	COG2814	Major facilitator Superfamily
A9498_RS10040	COG3384	dioxygenase
A9498_RS10050	COG3279	Response regulator of the LytR AlgR family
A9498_RS10055	COG0427	acetyl-CoA hydrolase
A9498_RS10075	COG4166	transmembrane transport
A9498_RS10080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9498_RS10100	COG1914	H( )-stimulated, divalent metal cation uptake system
A9498_RS10115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A9498_RS10120	COG0531	amino acid
A9498_RS10155	COG1309	transcriptional regulator
A9498_RS10160	COG2390	Transcriptional regulator
A9498_RS10170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A9498_RS10175	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A9498_RS10190	COG4846	Membrane protein involved in cytochrome C biogenesis
A9498_RS10210	COG2132	Multicopper oxidase
A9498_RS10325	COG1114	Component of the transport system for branched-chain amino acids
A9498_RS10340	COG1276	copper resistance
A9498_RS10340	COG2372	response to copper ion
A9498_RS10345	COG4549	nuclear export factor GLE1
A9498_RS10350	COG0697	spore germination
A9498_RS10355	COG0583	DNA-binding transcription factor activity
A9498_RS10360	COG1959	2 iron, 2 sulfur cluster binding
A9498_RS10365	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A9498_RS10370	COG0778	Nitroreductase
A9498_RS10380	COG0628	permease
A9498_RS10400	COG0523	cobalamin synthesis protein
A9498_RS10410	COG0411	ABC transporter
A9498_RS10430	COG0583	DNA-binding transcription factor activity
A9498_RS10460	COG1271	oxidase subunit
A9498_RS10465	COG1294	oxidase, subunit
A9498_RS10470	COG4988	ABC transporter
A9498_RS10475	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A9498_RS10485	COG1216	Glycosyl transferase, family 2
A9498_RS10525	COG1686	Belongs to the peptidase S11 family
A9498_RS10540	COG1388	LysM domain
A9498_RS10540	COG0791	NLP P60 protein
A9498_RS10550	COG1132	(ABC) transporter
A9498_RS10555	COG0745	RESPONSE REGULATOR receiver
A9498_RS10560	COG5002	protein histidine kinase activity
A9498_RS10565	COG0300	oxidoreductase activity
A9498_RS10595	COG0460	homoserine dehydrogenase
A9498_RS10620	COG1316	TRANSCRIPTIONal
A9498_RS10630	COG0745	RESPONSE REGULATOR receiver
A9498_RS10635	COG5002	protein histidine kinase activity
A9498_RS10650	COG1285	pathogenesis
A9498_RS10655	COG1247	-acetyltransferase
A9498_RS10690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A9498_RS10700	COG1082	Xylose isomerase domain protein TIM barrel
A9498_RS10710	COG2814	Major facilitator Superfamily
A9498_RS10715	COG1279	arginine transmembrane transporter activity
A9498_RS10720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A9498_RS10730	COG1752	Esterase of the alpha-beta hydrolase superfamily
A9498_RS10765	COG0577	efflux transmembrane transporter activity
A9498_RS10770	COG2002	toxin-antitoxin pair type II binding
A9498_RS10775	COG1404	Belongs to the peptidase S8 family
A9498_RS10790	COG3152	Membrane
A9498_RS10815	COG0840	transmembrane signaling receptor activity
A9498_RS10830	COG3949	Membrane
A9498_RS10835	COG0783	Belongs to the Dps family
A9498_RS10850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A9498_RS10865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9498_RS10870	COG4989	oxidoreductase activity
A9498_RS10875	COG0523	cobalamin synthesis protein
A9498_RS10880	COG0456	acetyltransferase
A9498_RS10885	COG0803	Belongs to the bacterial solute-binding protein 9 family
A9498_RS10890	COG0702	epimerase
A9498_RS10900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A9498_RS10935	COG5337	Spore coat protein CotH
A9498_RS10940	COG1051	belongs to the nudix hydrolase family
A9498_RS10945	COG0586	Pfam SNARE associated Golgi protein
A9498_RS10950	COG2244	polysaccharide biosynthetic process
A9498_RS10960	COG0701	Predicted permease
A9498_RS10965	COG3689	TIGRFAM TIGR03943 family protein
A9498_RS10970	COG1607	acyl-coa hydrolase
A9498_RS10980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9498_RS10995	COG0702	epimerase
A9498_RS11000	COG2839	Protein conserved in bacteria
A9498_RS11020	COG1114	Component of the transport system for branched-chain amino acids
A9498_RS11025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9498_RS11045	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9498_RS11055	COG1876	peptidase activity
A9498_RS11080	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9498_RS11090	COG0561	phosphatase activity
A9498_RS11105	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A9498_RS11125	COG1819	glycosyl
A9498_RS11130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9498_RS11135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A9498_RS11165	COG0456	acetyltransferase
A9498_RS11200	COG4499	WXG100 protein secretion system (Wss), protein YukC
A9498_RS11285	COG3874	Sporulation protein YtfJ
A9498_RS11310	COG2226	methyltransferase
A9498_RS11330	COG1082	Xylose isomerase domain protein TIM barrel
A9498_RS11335	COG0346	lactoylglutathione lyase activity
A9498_RS11345	COG0604	alcohol dehydrogenase
A9498_RS11350	COG1595	DNA-templated transcription, initiation
A9498_RS11365	COG0426	domain, Protein
A9498_RS11365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A9498_RS11375	COG0386	Belongs to the glutathione peroxidase family
A9498_RS11380	COG1305	Transglutaminase-like
A9498_RS11390	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A9498_RS11400	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A9498_RS11405	COG1140	nitrate reductase beta subunit
A9498_RS11410	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A9498_RS11415	COG2181	nitrate reductase activity
A9498_RS11420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A9498_RS11425	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A9498_RS11430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A9498_RS11435	COG0303	'Molybdopterin
A9498_RS11440	COG0314	molybdopterin synthase activity
A9498_RS11445	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A9498_RS11450	COG2223	nitrite transmembrane transporter activity
A9498_RS11470	COG1648	precorrin-2 dehydrogenase activity
A9498_RS11480	COG1587	Uroporphyrinogen-III synthase
A9498_RS11480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A9498_RS11485	COG2146	nitrite reductase [NAD(P)H] activity
A9498_RS11490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A9498_RS11495	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
A9498_RS11530	COG2359	stage V sporulation protein S
A9498_RS11550	COG0457	Tetratricopeptide repeat
A9498_RS11565	COG1418	mRNA catabolic process
A9498_RS11570	COG0488	(ABC) transporter
A9498_RS11585	COG0629	single-stranded DNA binding
A9498_RS11600	COG3344	reverse transcriptase
A9498_RS11610	COG1413	lyase activity
A9498_RS11625	COG2136	Putative SAM-dependent methyltransferase
A9498_RS11625	COG2521	methyltransferase
A9498_RS11630	COG0018	arginyl-trna synthetase
A9498_RS11675	COG0017	Asparaginyl-tRNA synthetase
A9498_RS11680	COG0733	neurotransmitter:sodium symporter activity
A9498_RS11705	COG2610	gluconate transmembrane transporter activity
A9498_RS11715	COG1794	racemase activity, acting on amino acids and derivatives
A9498_RS11725	COG0456	acetyltransferase
A9498_RS11735	COG3655	Transcriptional regulator
A9498_RS11740	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A9498_RS11750	COG1131	(ABC) transporter
A9498_RS11755	COG4473	ABC transporter
A9498_RS11765	COG0546	phosphoglycolate phosphatase activity
A9498_RS11780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A9498_RS11810	COG0204	Acyl-transferase
A9498_RS11815	COG1272	protein, Hemolysin III
A9498_RS11825	COG0805	protein transport
A9498_RS11835	COG1307	EDD domain protein, DegV family
A9498_RS11845	COG1999	signal sequence binding
A9498_RS11855	COG0367	asparagine synthase
A9498_RS11870	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9498_RS11880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A9498_RS11900	COG1335	isochorismatase
A9498_RS11920	COG2203	Gaf domain
A9498_RS11920	COG4585	Histidine kinase
A9498_RS11930	COG1737	Transcriptional regulator
A9498_RS11935	COG0384	phenazine biosynthesis protein PhzF
A9498_RS11940	COG1064	alcohol dehydrogenase
A9498_RS11965	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A9498_RS12000	COG1125	glycine betaine transport
A9498_RS12000	COG0517	IMP dehydrogenase activity
A9498_RS12005	COG1174	glycine betaine transport
A9498_RS12040	COG1253	flavin adenine dinucleotide binding
A9498_RS12045	COG1012	belongs to the aldehyde dehydrogenase family
A9498_RS12050	COG5506	Protein of unknown function (DUF1694)
A9498_RS12065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A9498_RS12070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A9498_RS12075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A9498_RS12085	COG0456	acetyltransferase
A9498_RS12090	COG3829	transcription factor binding
A9498_RS12130	COG0515	serine threonine protein kinase
A9498_RS12130	COG3064	Membrane
A9498_RS12130	COG4991	sh3 domain protein
A9498_RS12140	COG0671	phosphoesterase, PA-phosphatase related
A9498_RS12145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A9498_RS12150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9498_RS12250	COG2814	Major facilitator Superfamily
A9498_RS12255	COG4841	protein insertion into membrane
A9498_RS12265	COG2079	MmgE PrpD family protein
A9498_RS12270	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A9498_RS12275	COG1960	acyl-CoA dehydrogenase activity
A9498_RS12280	COG2084	Dehydrogenase
A9498_RS12290	COG1280	lysine exporter protein (LysE YggA)
A9498_RS12295	COG1024	Enoyl-CoA hydratase
A9498_RS12310	COG0420	3'-5' exonuclease activity
A9498_RS12315	COG0419	ATPase involved in DNA repair
A9498_RS12330	COG2223	nitrite transmembrane transporter activity
A9498_RS12335	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS12340	COG1169	isochorismate synthase
A9498_RS12345	COG1021	2,3-dihydroxybenzoate-AMP ligase
A9498_RS12350	COG3433	isochorismatase activity
A9498_RS12350	COG1535	isochorismatase
A9498_RS12360	COG3251	PFAM MbtH domain protein
A9498_RS12365	COG2814	Major facilitator Superfamily
A9498_RS12380	COG0776	regulation of translation
A9498_RS12390	COG2318	DinB family
A9498_RS12400	COG1115	amino acid carrier protein
A9498_RS12415	COG2329	Antibiotic biosynthesis monooxygenase
A9498_RS12420	COG1187	pseudouridine synthase activity
A9498_RS12430	COG1136	(ABC) transporter
A9498_RS12445	COG0028	Belongs to the TPP enzyme family
A9498_RS12480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A9498_RS12540	COG1247	-acetyltransferase
A9498_RS12565	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A9498_RS12610	COG0583	DNA-binding transcription factor activity
A9498_RS12615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A9498_RS12635	COG0583	DNA-binding transcription factor activity
A9498_RS12640	COG2258	MOSC domain
A9498_RS12655	COG1132	(ABC) transporter
A9498_RS12660	COG1132	(ABC) transporter
A9498_RS12685	COG1396	sequence-specific DNA binding
A9498_RS12720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9498_RS12725	COG1595	DNA-templated transcription, initiation
A9498_RS12745	COG1649	PFAM Uncharacterised BCR, COG1649
A9498_RS12790	COG1846	Transcriptional regulator
A9498_RS12830	COG1309	transcriptional regulator
A9498_RS12850	COG0500	methyltransferase
A9498_RS12850	COG3615	Tellurite resistance protein tehB
A9498_RS12860	COG2226	methyltransferase
A9498_RS12865	COG3961	Belongs to the TPP enzyme family
A9498_RS12870	COG1846	Transcriptional regulator
A9498_RS12900	COG2195	Cleaves the N-terminal amino acid of tripeptides
A9498_RS12925	COG2002	toxin-antitoxin pair type II binding
A9498_RS12940	COG0730	response to heat
A9498_RS12950	COG1686	Belongs to the peptidase S11 family
A9498_RS12990	COG2814	Major facilitator Superfamily
A9498_RS13020	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS13065	COG0741	lytic transglycosylase activity
A9498_RS13070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9498_RS13085	COG1396	sequence-specific DNA binding
A9498_RS13105	COG1309	transcriptional regulator
A9498_RS13120	COG4585	Histidine kinase
A9498_RS13160	COG1760	l-serine dehydratase
A9498_RS13165	COG1760	l-serine dehydratase
A9498_RS13170	COG0814	amino acid
A9498_RS13200	COG0076	glutamate decarboxylase activity
A9498_RS13235	COG0772	Belongs to the SEDS family
A9498_RS13240	COG2239	Acts as a magnesium transporter
A9498_RS13255	COG1595	DNA-templated transcription, initiation
A9498_RS13265	COG0768	penicillin binding
A9498_RS13290	COG1131	(ABC) transporter
A9498_RS13315	COG1960	acyl-CoA dehydrogenase activity
A9498_RS13320	COG0439	Biotin carboxylase
A9498_RS13325	COG0511	ligase activity, forming carbon-carbon bonds
A9498_RS13330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A9498_RS13335	COG1024	Enoyl-CoA hydratase
A9498_RS13340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A9498_RS13390	COG0572	uridine kinase
A9498_RS13410	COG1686	Belongs to the peptidase S11 family
A9498_RS13435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A9498_RS13450	COG3227	Zinc metalloprotease (Elastase)
A9498_RS13455	COG2207	Transcriptional regulator
A9498_RS13490	COG2814	Major facilitator Superfamily
A9498_RS13495	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS13500	COG1733	regulation of RNA biosynthetic process
A9498_RS13550	COG0697	spore germination
A9498_RS13555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A9498_RS13560	COG2368	4-hydroxyphenylacetate
A9498_RS13585	COG2323	membrane
A9498_RS13605	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
A9498_RS13610	COG3773	Cell wall hydrolase
A9498_RS13620	COG0745	RESPONSE REGULATOR receiver
A9498_RS13625	COG2205	protein histidine kinase activity
A9498_RS13630	COG0488	(ABC) transporter
A9498_RS13640	COG1136	(ABC) transporter
A9498_RS13645	COG0577	efflux transmembrane transporter activity
A9498_RS13680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A9498_RS13745	COG1396	sequence-specific DNA binding
A9498_RS13765	COG2002	toxin-antitoxin pair type II binding
A9498_RS13815	COG0582	viral genome integration into host DNA
A9498_RS13870	COG1802	Transcriptional regulator
A9498_RS13870	COG4626	Terminase
A9498_RS13880	COG0740	serine-type endopeptidase activity
A9498_RS14010	COG2124	cytochrome p450
A9498_RS14050	COG0561	phosphatase activity
A9498_RS14055	COG5002	protein histidine kinase activity
A9498_RS14060	COG0768	penicillin binding
A9498_RS14070	COG1819	glycosyl
A9498_RS14075	COG1794	racemase activity, acting on amino acids and derivatives
A9498_RS14100	COG2205	protein histidine kinase activity
A9498_RS14170	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A9498_RS14180	COG0745	RESPONSE REGULATOR receiver
A9498_RS14185	COG5002	protein histidine kinase activity
A9498_RS14195	COG0671	phosphoesterase, PA-phosphatase related
A9498_RS14200	COG0768	penicillin binding
A9498_RS14255	COG0693	protein deglycase activity
A9498_RS14335	COG0592	DNA-directed DNA polymerase activity
A9498_RS14365	COG3878	Protein conserved in bacteria
A9498_RS14390	COG4667	esterase of the alpha-beta hydrolase superfamily
A9498_RS14430	COG0322	excinuclease ABC activity
A9498_RS14470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9498_RS14500	COG1011	Hydrolase
A9498_RS14505	COG0745	RESPONSE REGULATOR receiver
A9498_RS14525	COG1136	(ABC) transporter
A9498_RS14535	COG1073	alpha beta
A9498_RS14540	COG0657	acetylesterase activity
A9498_RS14545	COG0076	glutamate decarboxylase activity
A9498_RS14565	COG3227	Zinc metalloprotease (Elastase)
A9498_RS14570	COG0737	Belongs to the 5'-nucleotidase family
A9498_RS14585	COG0201	protein transport
A9498_RS14630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9498_RS14645	COG2959	enzyme of heme biosynthesis
A9498_RS14685	COG1309	transcriptional regulator
A9498_RS14720	COG3284	Transcriptional regulator
A9498_RS14735	COG1349	DNA-binding transcription factor activity
A9498_RS14750	COG1959	2 iron, 2 sulfur cluster binding
A9498_RS14765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9498_RS14770	COG0508	dehydrogenase complex catalyzes the overall conversion of
A9498_RS14775	COG0022	dehydrogenase e1 component
A9498_RS14780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A9498_RS14800	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS14830	COG4176	ABC-type proline glycine betaine transport system permease component
A9498_RS14835	COG4175	Glycine betaine
A9498_RS14835	COG0517	IMP dehydrogenase activity
A9498_RS14865	COG2153	protein acetylation
A9498_RS14905	COG2315	Protein conserved in bacteria
A9498_RS14950	COG0456	acetyltransferase
A9498_RS14955	COG3973	AAA domain
A9498_RS14965	COG2105	PFAM AIG2 family protein
A9498_RS14970	COG0514	ATP-dependent DNA helicase (RecQ)
A9498_RS15010	COG4637	Psort location Cytoplasmic, score
A9498_RS15025	COG3397	chitin binding
A9498_RS15040	COG1162	GTPase activity
A9498_RS15045	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A9498_RS15050	COG1115	amino acid carrier protein
A9498_RS15055	COG1012	belongs to the aldehyde dehydrogenase family
A9498_RS15060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A9498_RS15070	COG3938	Belongs to the proline racemase family
A9498_RS15075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9498_RS15120	COG0586	Pfam SNARE associated Golgi protein
A9498_RS15140	COG4166	transmembrane transport
A9498_RS15150	COG4948	Mandelate Racemase Muconate Lactonizing
A9498_RS15165	COG0667	Aldo Keto reductase
A9498_RS15215	COG0745	RESPONSE REGULATOR receiver
A9498_RS15255	COG0531	amino acid
A9498_RS15260	COG1522	sequence-specific DNA binding
A9498_RS15265	COG1307	EDD domain protein, DegV family
A9498_RS15315	COG2814	Major facilitator Superfamily
A9498_RS15325	COG1664	Polymer-forming cytoskeletal
A9498_RS15335	COG4533	DNA binding
A9498_RS15340	COG0477	Major facilitator Superfamily
A9498_RS15340	COG2814	Major facilitator Superfamily
A9498_RS15365	COG2261	transglycosylase associated protein
A9498_RS15380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A9498_RS15415	COG0436	Aminotransferase
A9498_RS15420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A9498_RS15430	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A9498_RS15495	COG0628	permease
A9498_RS15510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A9498_RS15515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A9498_RS15545	COG2746	aminoglycoside 3-N-acetyltransferase activity
A9498_RS15565	COG0697	spore germination
A9498_RS15570	COG4912	Dna alkylation repair
A9498_RS15575	COG0346	lactoylglutathione lyase activity
A9498_RS15580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9498_RS15590	COG0861	Integral membrane protein TerC family
A9498_RS15595	COG1368	sulfuric ester hydrolase activity
A9498_RS15605	COG1033	growth of symbiont in host cell
A9498_RS15605	COG2409	Drug exporters of the RND superfamily
A9498_RS15610	COG1309	transcriptional regulator
A9498_RS15625	COG0287	Prephenate dehydrogenase
A9498_RS15640	COG1605	Chorismate mutase
A9498_RS15640	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A9498_RS15690	COG3584	3D domain protein
A9498_RS15690	COG1388	LysM domain
A9498_RS15730	COG1879	ABC-type sugar transport system periplasmic component
A9498_RS15735	COG1172	Belongs to the binding-protein-dependent transport system permease family
A9498_RS15750	COG2390	Transcriptional regulator
A9498_RS15775	COG2329	Antibiotic biosynthesis monooxygenase
A9498_RS15800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A9498_RS15815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A9498_RS15820	COG4187	Peptidase family M20/M25/M40
A9498_RS15825	COG1414	Transcriptional regulator
A9498_RS15850	COG3239	Fatty acid desaturase
A9498_RS15860	COG2720	vancomycin resistance protein
A9498_RS15875	COG3655	Transcriptional regulator
A9498_RS15900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9498_RS15905	COG0346	lactoylglutathione lyase activity
A9498_RS15930	COG0714	Associated with various cellular activities
A9498_RS15955	COG0463	Glycosyl transferase, family 2
A9498_RS15985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A9498_RS16075	COG0778	Nitroreductase
A9498_RS16080	COG1846	Transcriptional regulator
A9498_RS16100	COG3831	ATPase activity
A9498_RS16100	COG4884	unkown
A9498_RS16130	COG0456	acetyltransferase
A9498_RS16145	COG0697	spore germination
A9498_RS16150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A9498_RS16200	COG0730	response to heat
A9498_RS16290	COG1984	allophanate hydrolase subunit 2
A9498_RS16295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A9498_RS16300	COG1414	Transcriptional regulator
A9498_RS16310	COG3142	Participates in the control of copper homeostasis
A9498_RS16315	COG0640	Transcriptional regulator
A9498_RS16325	COG1960	acyl-CoA dehydrogenase activity
A9498_RS16345	COG3314	Sporulation integral membrane protein YlbJ
A9498_RS16365	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
A9498_RS16380	COG0574	Belongs to the PEP-utilizing enzyme family
A9498_RS16380	COG3848	Pyruvate phosphate dikinase
A9498_RS16385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9498_RS16405	COG1063	alcohol dehydrogenase
A9498_RS16415	COG1027	Aspartate ammonia-lyase
A9498_RS16420	COG0252	asparaginase activity
A9498_RS16425	COG1396	sequence-specific DNA binding
A9498_RS16495	COG2207	Transcriptional regulator
A9498_RS16515	COG0322	excinuclease ABC activity
A9498_RS16520	COG0531	amino acid
A9498_RS16525	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A9498_RS16545	COG0784	Response regulator, receiver
A9498_RS16550	COG4191	Histidine kinase
A9498_RS16560	COG1115	amino acid carrier protein
A9498_RS16585	COG2267	carboxylic ester hydrolase activity
A9498_RS16590	COG1335	isochorismatase
A9498_RS16680	COG1846	Transcriptional regulator
A9498_RS16710	COG2814	Major facilitator Superfamily
A9498_RS16720	COG0657	acetylesterase activity
A9498_RS16725	COG0288	reversible hydration of carbon dioxide
A9498_RS16735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A9498_RS16740	COG5609	conserved protein (DUF2294)
A9498_RS16805	COG2962	Rard protein
A9498_RS16815	COG3344	reverse transcriptase
A9498_RS16825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9498_RS16840	COG0798	PFAM Bile acid sodium symporter
A9498_RS16845	COG0346	lactoylglutathione lyase activity
A9498_RS16850	COG0640	Transcriptional regulator
A9498_RS16920	COG2814	Major facilitator Superfamily
A9498_RS16925	COG1309	transcriptional regulator
A9498_RS16930	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS16935	COG1522	sequence-specific DNA binding
A9498_RS16950	COG0346	lactoylglutathione lyase activity
A9498_RS17035	COG2814	Major facilitator Superfamily
A9498_RS17050	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A9498_RS17090	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A9498_RS17110	COG0577	efflux transmembrane transporter activity
A9498_RS17115	COG5002	protein histidine kinase activity
A9498_RS17115	COG3850	Histidine kinase
A9498_RS17125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9498_RS17160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A9498_RS17190	COG3831	ATPase activity
A9498_RS17205	COG3409	Peptidoglycan-binding domain 1 protein
A9498_RS17205	COG5632	N-Acetylmuramoyl-L-alanine amidase
A9498_RS17375	COG5444	nuclease activity
A9498_RS17435	COG1876	peptidase activity
A9498_RS17440	COG2843	Capsule synthesis protein
A9498_RS17450	COG0477	Major facilitator Superfamily
A9498_RS17465	COG1846	Transcriptional regulator
A9498_RS17490	COG2031	fatty acid transporter
A9498_RS17500	COG2249	NAD(P)H dehydrogenase (quinone) activity
A9498_RS17560	COG1288	antiporter activity
A9498_RS17565	COG2356	endonuclease I
A9498_RS17585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A9498_RS17595	COG1733	regulation of RNA biosynthetic process
A9498_RS17600	COG0778	Nitroreductase
A9498_RS17640	COG1131	(ABC) transporter
A9498_RS17665	COG1011	Hydrolase
A9498_RS17675	COG2365	Tyrosine phosphatase family
A9498_RS17720	COG0628	permease
A9498_RS17745	COG0500	methyltransferase
A9498_RS17755	COG0477	Major facilitator Superfamily
A9498_RS17785	COG1253	flavin adenine dinucleotide binding
A9498_RS17790	COG0789	Transcriptional regulator
A9498_RS17800	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A9498_RS17835	COG1357	PFAM Pentapeptide repeats (8 copies)
A9498_RS17840	COG3813	Protein conserved in bacteria
A9498_RS17845	COG2706	6-phosphogluconolactonase activity
A9498_RS17850	COG1070	Carbohydrate kinase
A9498_RS17860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A9498_RS17865	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A9498_RS17870	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A9498_RS17875	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A9498_RS17900	COG0840	transmembrane signaling receptor activity
A9498_RS17915	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9498_RS17915	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9498_RS17920	COG1733	regulation of RNA biosynthetic process
A9498_RS17945	COG2824	Alkylphosphonate utilization operon protein PhnA
A9498_RS17950	COG0659	secondary active sulfate transmembrane transporter activity
A9498_RS17965	COG0814	amino acid
A9498_RS17995	COG2188	Transcriptional regulator
A9498_RS18000	COG0673	inositol 2-dehydrogenase activity
A9498_RS18020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9498_RS18040	COG0384	phenazine biosynthesis protein PhzF
A9498_RS18045	COG0318	PFAM AMP-dependent synthetase and ligase
A9498_RS18050	COG2249	NAD(P)H dehydrogenase (quinone) activity
A9498_RS18055	COG1733	regulation of RNA biosynthetic process
A9498_RS18085	COG1191	sigma factor activity
A9498_RS18120	COG3152	Membrane
A9498_RS18150	COG1151	hydroxylamine reductase activity
A9498_RS18180	COG2072	flavoprotein involved in K transport
A9498_RS18220	COG1113	amino acid transport
A9498_RS18225	COG2814	Major facilitator Superfamily
A9498_RS18260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A9498_RS18265	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A9498_RS18275	COG1247	-acetyltransferase
A9498_RS18280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A9498_RS18285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9498_RS18290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9498_RS18315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9498_RS18340	COG2890	protein-(glutamine-N5) methyltransferase activity
A9498_RS18355	COG1193	negative regulation of DNA recombination
A9498_RS18370	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A9498_RS18375	COG1164	Oligoendopeptidase f
A9498_RS18405	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A9498_RS18430	COG0584	glycerophosphoryl diester phosphodiesterase
A9498_RS18440	COG0640	Transcriptional regulator
A9498_RS18445	COG0604	alcohol dehydrogenase
A9498_RS18465	COG2808	Putative FMN-binding domain
A9498_RS18470	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A9498_RS18470	COG0456	acetyltransferase
A9498_RS18480	COG0385	Bile acid
A9498_RS18485	COG0277	FAD linked oxidase domain protein
A9498_RS18510	COG1183	phosphatidylcholine synthase activity
A9498_RS18520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9498_RS18520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9498_RS18525	COG1252	NADH dehydrogenase
A9498_RS18535	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A9498_RS18545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A9498_RS18560	COG0457	Tetratricopeptide repeat
A9498_RS18640	COG0488	(ABC) transporter
A9498_RS18665	COG3852	Histidine kinase
A9498_RS18675	COG1285	pathogenesis
A9498_RS18685	COG2514	catechol 2,3-dioxygenase activity
A9498_RS18690	COG2720	vancomycin resistance protein
A9498_RS18725	COG0716	FMN binding
A9498_RS18740	COG0494	nUDIX hydrolase
A9498_RS18760	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS18770	COG0165	Argininosuccinate lyase
A9498_RS18785	COG4145	pantothenate transmembrane transporter activity
A9498_RS18795	COG1012	belongs to the aldehyde dehydrogenase family
A9498_RS18800	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS18810	COG1657	PFAM Prenyltransferase squalene oxidase
A9498_RS18815	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A9498_RS18820	COG2962	Rard protein
A9498_RS18825	COG3326	Membrane
A9498_RS18840	COG0489	protein tyrosine kinase activity
A9498_RS18850	COG0314	molybdopterin synthase activity
A9498_RS18855	COG0303	'Molybdopterin
A9498_RS18860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A9498_RS18865	COG2116	formate transmembrane transporter activity
A9498_RS18875	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A9498_RS18880	COG5609	conserved protein (DUF2294)
A9498_RS18885	COG2427	Protein of unknown function (DUF1641)
A9498_RS18890	COG3383	formate dehydrogenase (NAD+) activity
A9498_RS18895	COG0697	spore germination
A9498_RS18910	COG0531	amino acid
A9498_RS18945	COG2226	methyltransferase
A9498_RS18955	COG4166	transmembrane transport
A9498_RS18960	COG4166	transmembrane transport
A9498_RS18965	COG1316	TRANSCRIPTIONal
A9498_RS18975	COG1595	DNA-templated transcription, initiation
A9498_RS18985	COG1131	(ABC) transporter
A9498_RS19010	COG0673	inositol 2-dehydrogenase activity
A9498_RS19015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A9498_RS19020	COG0187	DNA topoisomerase II activity
A9498_RS19025	COG1832	CoA-binding protein
A9498_RS19030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A9498_RS19035	COG0745	RESPONSE REGULATOR receiver
A9498_RS19045	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A9498_RS19045	COG1328	CTP reductase activity
A9498_RS19055	COG4841	protein insertion into membrane
A9498_RS19060	COG0824	Thioesterase
A9498_RS19110	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A9498_RS19160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A9498_RS19175	COG0183	Belongs to the thiolase family
A9498_RS19180	COG0318	PFAM AMP-dependent synthetase and ligase
A9498_RS19185	COG1268	BioY protein
A9498_RS19190	COG0318	PFAM AMP-dependent synthetase and ligase
A9498_RS19195	COG1396	sequence-specific DNA binding
A9498_RS19225	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A9498_RS19245	COG0830	nickel cation binding
A9498_RS19285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9498_RS19305	COG0400	carboxylic ester hydrolase activity
A9498_RS19310	COG0346	lactoylglutathione lyase activity
A9498_RS19320	COG0069	glutamate synthase activity
A9498_RS19325	COG1902	pentaerythritol trinitrate reductase activity
A9498_RS19330	COG1329	Transcriptional regulator
A9498_RS19335	COG0010	Belongs to the arginase family
A9498_RS19360	COG2226	methyltransferase
A9498_RS19390	COG4846	Membrane protein involved in cytochrome C biogenesis
A9498_RS19395	COG0785	Cytochrome C biogenesis protein
A9498_RS19410	COG1473	amidohydrolase
A9498_RS19445	COG1346	cytolysis
A9498_RS19460	COG0730	response to heat
A9498_RS19485	COG1132	(ABC) transporter
A9498_RS19490	COG1132	(ABC) transporter
A9498_RS19530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9498_RS19565	COG1695	Transcriptional regulator
A9498_RS19580	COG3409	Peptidoglycan-binding domain 1 protein
A9498_RS19580	COG5632	N-Acetylmuramoyl-L-alanine amidase
A9498_RS19580	COG1388	LysM domain
A9498_RS19585	COG5632	N-Acetylmuramoyl-L-alanine amidase
A9498_RS19585	COG1388	LysM domain
A9498_RS19585	COG3409	Peptidoglycan-binding domain 1 protein
A9498_RS19590	COG1388	LysM domain
A9498_RS19590	COG3409	Peptidoglycan-binding domain 1 protein
A9498_RS19590	COG5632	N-Acetylmuramoyl-L-alanine amidase
A9498_RS19595	COG3409	Peptidoglycan-binding domain 1 protein
A9498_RS19595	COG5632	N-Acetylmuramoyl-L-alanine amidase
A9498_RS19595	COG1388	LysM domain
A9498_RS19600	COG1388	LysM domain
A9498_RS19600	COG5632	N-Acetylmuramoyl-L-alanine amidase
A9498_RS19600	COG3409	Peptidoglycan-binding domain 1 protein
A9498_RS19605	COG0741	lytic transglycosylase activity
A9498_RS19605	COG0739	heme binding
A9498_RS19605	COG1196	nuclear chromosome segregation
A9498_RS19610	COG0741	lytic transglycosylase activity
A9498_RS19645	COG0174	glutamine synthetase
A9498_RS19650	COG0789	Transcriptional regulator
A9498_RS19655	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A9498_RS19660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A9498_RS19670	COG0464	growth
A9498_RS19710	COG1388	LysM domain
A9498_RS19710	COG3584	3D domain protein
A9498_RS19720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9498_RS19720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9498_RS19720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9498_RS19725	COG1105	Belongs to the carbohydrate kinase PfkB family
A9498_RS19730	COG1349	DNA-binding transcription factor activity
A9498_RS19740	COG2322	membrane
A9498_RS19750	COG1113	amino acid transport
A9498_RS19765	COG1408	metallophosphoesterase
A9498_RS19770	COG2116	formate transmembrane transporter activity
A9498_RS19785	COG2217	Heavy metal translocating P-type atpase
A9498_RS19790	COG2608	mercury ion transmembrane transporter activity
A9498_RS19795	COG1937	Protein conserved in bacteria
A9498_RS19805	COG2819	hydrolase of the alpha beta superfamily
A9498_RS19810	COG1120	ATPase activity
A9498_RS19815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9498_RS19820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9498_RS19835	COG2169	Transcriptional regulator
A9498_RS19840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A9498_RS19845	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A9498_RS19855	COG2364	Membrane
A9498_RS19870	COG2267	carboxylic ester hydrolase activity
A9498_RS19875	COG3300	MHYT domain
A9498_RS19875	COG5001	Diguanylate cyclase
A9498_RS19895	COG1086	Polysaccharide biosynthesis protein
A9498_RS19915	COG1346	cytolysis
A9498_RS19925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A9498_RS19935	COG2188	Transcriptional regulator
A9498_RS19940	COG2723	6-phospho-beta-galactosidase activity
A9498_RS19950	COG1404	Belongs to the peptidase S8 family
A9498_RS19955	COG3773	Cell wall hydrolase
A9498_RS19970	COG1368	sulfuric ester hydrolase activity
A9498_RS19975	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A9498_RS20000	COG4550	Control of competence regulator ComK, YlbF/YmcA
A9498_RS20010	COG1013	pyruvate-flavodoxin oxidoreductase activity
A9498_RS20015	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A9498_RS20015	COG0674	pyruvate-flavodoxin oxidoreductase activity
A9498_RS20025	COG2359	stage V sporulation protein S
A9498_RS20030	COG1692	metallophosphoesterase
A9498_RS20055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A9498_RS20060	COG1426	Protein conserved in bacteria
A9498_RS20075	COG0300	oxidoreductase activity
A9498_RS20080	COG0612	Peptidase, M16
A9498_RS20085	COG0612	Peptidase, M16
A9498_RS20090	COG1079	Belongs to the binding-protein-dependent transport system permease family
A9498_RS20095	COG4603	Belongs to the binding-protein-dependent transport system permease family
A9498_RS20100	COG3845	ABC transporter
A9498_RS20105	COG1744	ABC transporter substrate-binding protein PnrA-like
A9498_RS20110	COG2188	Transcriptional regulator
A9498_RS20135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A9498_RS20145	COG0527	aspartate kinase activity
A9498_RS20150	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A9498_RS20155	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A9498_RS20250	COG3344	reverse transcriptase
A9498_RS20265	COG1278	Cold shock
A9498_RS20270	COG0582	viral genome integration into host DNA
A9498_RS20325	COG0305	Participates in initiation and elongation during chromosome replication
A9498_RS20390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A9498_RS20395	COG1873	PFAM PRC-barrel domain
A9498_RS20400	COG0612	Peptidase, M16
A9498_RS20405	COG0726	polysaccharide deacetylase
A9498_RS20420	COG0196	riboflavin kinase activity
A9498_RS20430	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A9498_RS20435	COG1550	Protein conserved in bacteria
A9498_RS20445	COG1358	cellular component organization or biogenesis
A9498_RS20450	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A9498_RS20455	COG0195	Participates in both transcription termination and antitermination
A9498_RS20475	COG0750	zinc metalloprotease
A9498_RS20485	COG4589	Belongs to the CDS family
A9498_RS20530	COG4974	Belongs to the 'phage' integrase family
A9498_RS20545	COG0758	DNA mediated transformation
A9498_RS20550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A9498_RS20590	COG1837	Belongs to the UPF0109 family
A9498_RS20600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A9498_RS20610	COG0552	protein localization to endoplasmic reticulum
A9498_RS20615	COG1196	nuclear chromosome segregation
A9498_RS20625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A9498_RS20630	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS20635	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A9498_RS20650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A9498_RS20655	COG1461	Dihydroxyacetone kinase
A9498_RS20660	COG1302	Protein conserved in bacteria
A9498_RS20675	COG1564	THIamine pyrophosphokinase
A9498_RS20680	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A9498_RS20690	COG0515	serine threonine protein kinase
A9498_RS20690	COG2815	serine threonine protein kinase
A9498_RS20695	COG0631	protein serine/threonine phosphatase activity
A9498_RS20705	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A9498_RS20705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A9498_RS20725	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A9498_RS20745	COG1561	YicC-like family, N-terminal region
A9498_RS20750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A9498_RS20760	COG0006	proline dipeptidase activity
A9498_RS20785	COG3069	C4-dicarboxylate transmembrane transporter activity
A9498_RS20850	COG0564	pseudouridine synthase activity
A9498_RS20870	COG3599	regulation of cell shape
A9498_RS20875	COG2302	S4 RNA-binding domain
A9498_RS20880	COG0762	integral membrane protein
A9498_RS20890	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A9498_RS20900	COG1873	PFAM PRC-barrel domain
A9498_RS20905	COG1191	sigma factor activity
A9498_RS20910	COG1191	sigma factor activity
A9498_RS20920	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A9498_RS20925	COG0849	cell division
A9498_RS20945	COG0772	Belongs to the SEDS family
A9498_RS20965	COG0768	penicillin binding
A9498_RS20970	COG0768	penicillin binding
A9498_RS20990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A9498_RS21005	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A9498_RS21010	COG1399	metal-binding, possibly nucleic acid-binding protein
A9498_RS21020	COG3480	Lon protease (S16) C-terminal proteolytic domain
A9498_RS21025	COG1752	Esterase of the alpha-beta hydrolase superfamily
A9498_RS21030	COG3314	Sporulation integral membrane protein YlbJ
A9498_RS21040	COG0742	ribosomal rna small subunit methyltransferase
A9498_RS21055	COG3679	Belongs to the UPF0342 family
A9498_RS21060	COG0406	alpha-ribazole phosphatase activity
A9498_RS21075	COG2340	Cysteine-rich secretory protein family
A9498_RS21090	COG3336	cytochrome c oxidase
A9498_RS21130	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A9498_RS21140	COG0772	Belongs to the SEDS family
A9498_RS21150	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A9498_RS21155	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A9498_RS21165	COG4896	Protein conserved in bacteria
A9498_RS21185	COG1217	gtp-binding protein TYPA
A9498_RS21195	COG0483	inositol monophosphate 1-phosphatase activity
A9498_RS21215	COG1982	Orn Lys Arg decarboxylase major
A9498_RS21260	COG0022	dehydrogenase e1 component
A9498_RS21265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A9498_RS21280	COG0561	phosphatase activity
A9498_RS21295	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A9498_RS21300	COG0569	domain protein
A9498_RS21320	COG0583	DNA-binding transcription factor activity
A9498_RS21325	COG0517	IMP dehydrogenase activity
A9498_RS21340	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
A9498_RS21345	COG4703	Protein of unknown function (DUF1797)
A9498_RS21360	COG2200	EAL domain
A9498_RS21365	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS21370	COG1408	metallophosphoesterase
A9498_RS21415	COG2814	Major facilitator Superfamily
A9498_RS21435	COG3209	COG3209 Rhs family protein
A9498_RS21445	COG2205	protein histidine kinase activity
A9498_RS21455	COG0436	Aminotransferase
A9498_RS21460	COG1609	Transcriptional regulator
A9498_RS21465	COG3833	ABC-type maltose transport systems, permease component
A9498_RS21470	COG1175	transmembrane transport
A9498_RS21475	COG2182	Extracellular solute-binding protein
A9498_RS21485	COG0366	Alpha amylase catalytic
A9498_RS21490	COG3842	ATPase activity
A9498_RS21535	COG0183	Belongs to the thiolase family
A9498_RS21575	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS21595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A9498_RS21600	COG0436	Aminotransferase
A9498_RS21635	COG2084	Dehydrogenase
A9498_RS21645	COG2199	diguanylate cyclase activity
A9498_RS21650	COG0778	Nitroreductase
A9498_RS21675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9498_RS21675	COG1263	PTS System
A9498_RS21675	COG2190	(PTS) system
A9498_RS21680	COG3711	transcriptional antiterminator
A9498_RS21690	COG2188	Transcriptional regulator
A9498_RS21700	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A9498_RS21730	COG1547	Domain of unknown function (DUF309)
A9498_RS21735	COG0456	acetyltransferase
A9498_RS21740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A9498_RS21745	COG4086	secreted protein
A9498_RS21750	COG0561	phosphatase activity
A9498_RS21755	COG0697	spore germination
A9498_RS21770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A9498_RS21795	COG0733	neurotransmitter:sodium symporter activity
A9498_RS21815	COG1686	Belongs to the peptidase S11 family
A9498_RS21825	COG1725	Transcriptional regulator
A9498_RS21830	COG1131	(ABC) transporter
A9498_RS21845	COG1846	Transcriptional regulator
A9498_RS21860	COG0598	Magnesium transport protein CorA
A9498_RS21885	COG4974	Belongs to the 'phage' integrase family
A9498_RS21895	COG0735	belongs to the Fur family
A9498_RS21900	COG1300	Membrane
A9498_RS21920	COG0667	Aldo Keto reductase
A9498_RS21925	COG0656	L-ascorbic acid biosynthetic process
A9498_RS21930	COG0456	acetyltransferase
A9498_RS21930	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A9498_RS21940	COG1525	nuclease
A9498_RS21940	COG0737	Belongs to the 5'-nucleotidase family
A9498_RS21940	COG4085	toxin activity
A9498_RS21950	COG0596	Alpha beta hydrolase
A9498_RS21955	COG2056	Na+-H+ antiporter family
A9498_RS21960	COG1609	Transcriptional regulator
A9498_RS21965	COG0456	acetyltransferase
A9498_RS21970	COG1073	alpha beta
A9498_RS21990	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A9498_RS21990	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A9498_RS21995	COG0307	riboflavin synthase, alpha
A9498_RS22025	COG2226	methyltransferase
A9498_RS22025	COG1073	alpha beta
A9498_RS22040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A9498_RS22050	COG1757	Na H antiporter
A9498_RS22055	COG0737	Belongs to the 5'-nucleotidase family
A9498_RS22065	COG1522	sequence-specific DNA binding
A9498_RS22110	COG0300	oxidoreductase activity
A9498_RS22115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9498_RS22120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A9498_RS22125	COG1760	l-serine dehydratase
A9498_RS22130	COG1760	l-serine dehydratase
A9498_RS22160	COG1285	pathogenesis
A9498_RS22170	COG2195	Cleaves the N-terminal amino acid of tripeptides
A9498_RS22175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9498_RS22185	COG1376	ErfK ybiS ycfS ynhG family protein
A9498_RS22190	COG4129	membrane
A9498_RS22195	COG1126	abc transporter atp-binding protein
A9498_RS22200	COG0765	amino acid transport
A9498_RS22205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9498_RS22225	COG2323	membrane
A9498_RS22230	COG0772	Belongs to the SEDS family
A9498_RS22235	COG0508	dehydrogenase complex catalyzes the overall conversion of
A9498_RS22245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A9498_RS22250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9498_RS22265	COG0280	phosphate acetyltransferase
A9498_RS22275	COG3829	transcription factor binding
A9498_RS22275	COG3290	protein histidine kinase activity
A9498_RS22285	COG0584	glycerophosphoryl diester phosphodiesterase
A9498_RS22290	COG3093	addiction module antidote protein HigA
A9498_RS22320	COG0457	Tetratricopeptide repeat
A9498_RS22345	COG0582	viral genome integration into host DNA
A9498_RS22385	COG0789	Transcriptional regulator
A9498_RS22410	COG0750	zinc metalloprotease
A9498_RS22415	COG0497	DNA recombination
A9498_RS22425	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A9498_RS22435	COG0142	geranyltranstransferase activity
A9498_RS22460	COG1302	Protein conserved in bacteria
A9498_RS22465	COG0439	Biotin carboxylase
A9498_RS22470	COG0511	ligase activity, forming carbon-carbon bonds
A9498_RS22515	COG3854	ATPases associated with a variety of cellular activities
A9498_RS22540	COG0006	proline dipeptidase activity
A9498_RS22555	COG3872	metal-dependent enzyme
A9498_RS22565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A9498_RS22605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9498_RS22615	COG1609	Transcriptional regulator
A9498_RS22625	COG2076	Multidrug Resistance protein
A9498_RS22630	COG2076	Multidrug Resistance protein
A9498_RS22660	COG1131	(ABC) transporter
A9498_RS22665	COG1725	Transcriptional regulator
A9498_RS22700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A9498_RS22765	COG1459	type II secretion system
A9498_RS22770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A9498_RS22825	COG1410	methionine synthase
A9498_RS22825	COG0646	methionine synthase
A9498_RS22830	COG0646	methionine synthase
A9498_RS22830	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A9498_RS22835	COG0626	cystathionine gamma-synthase activity
A9498_RS22840	COG0626	cystathionine gamma-synthase activity
A9498_RS22860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9498_RS22870	COG1940	carbohydrate kinase activity
A9498_RS22875	COG4483	Protein conserved in bacteria
A9498_RS22880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A9498_RS22885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A9498_RS22890	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A9498_RS22895	COG0704	Plays a role in the regulation of phosphate uptake
A9498_RS22905	COG0573	inorganic phosphate transmembrane transporter activity
A9498_RS22910	COG0573	inorganic phosphate transmembrane transporter activity
A9498_RS22915	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A9498_RS22920	COG0768	penicillin binding
A9498_RS22925	COG0477	Major facilitator Superfamily
A9498_RS22930	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A9498_RS22940	COG5521	maltodextrose utilization protein MalA
A9498_RS22955	COG0735	belongs to the Fur family
A9498_RS22960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A9498_RS22965	COG1121	(ABC) transporter
A9498_RS22970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9498_RS23000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A9498_RS23005	COG2384	SAM-dependent methyltransferase
A9498_RS23015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A9498_RS23020	COG0358	DNA primase activity
A9498_RS23030	COG0517	IMP dehydrogenase activity
A9498_RS23045	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A9498_RS23050	COG0295	cytidine deaminase activity
A9498_RS23055	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A9498_RS23065	COG1480	7TM receptor with intracellular HD hydrolase
A9498_RS23070	COG1702	phosphate starvation-inducible protein PhoH
A9498_RS23090	COG1610	YqeY-like protein
A9498_RS23095	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A9498_RS23100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A9498_RS23105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A9498_RS23135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A9498_RS23140	COG1733	regulation of RNA biosynthetic process
A9498_RS23165	COG1466	dna polymerase III delta subunit
A9498_RS23175	COG0658	competence protein
A9498_RS23175	COG2333	competence protein COMEC
A9498_RS23180	COG2131	deaminase
A9498_RS23185	COG1555	photosystem II stabilization
A9498_RS23185	COG1596	polysaccharide export
A9498_RS23190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A9498_RS23195	COG2226	methyltransferase
A9498_RS23200	COG0799	negative regulation of ribosome biogenesis
A9498_RS23205	COG1713	HD superfamily hydrolase involved in NAD metabolism
A9498_RS23215	COG1534	Rna-binding protein
A9498_RS23225	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A9498_RS23230	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A9498_RS23265	COG1595	DNA-templated transcription, initiation
A9498_RS23275	COG0778	Nitroreductase
A9498_RS23280	COG2357	RelA SpoT domain protein
A9498_RS23290	COG1785	Belongs to the alkaline phosphatase family
A9498_RS23300	COG2267	carboxylic ester hydrolase activity
A9498_RS23340	COG3186	Phenylalanine-4-hydroxylase
A9498_RS23350	COG2514	catechol 2,3-dioxygenase activity
A9498_RS23355	COG2259	Doxx family
A9498_RS23395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A9498_RS23420	COG1012	belongs to the aldehyde dehydrogenase family
A9498_RS23420	COG1454	alcohol dehydrogenase
A9498_RS23425	COG0626	cystathionine gamma-synthase activity
A9498_RS23430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A9498_RS23455	COG0768	penicillin binding
A9498_RS23475	COG0826	peptidase U32
A9498_RS23480	COG0826	peptidase U32
A9498_RS23485	COG4122	O-methyltransferase activity
A9498_RS23490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A9498_RS23520	COG0628	permease
A9498_RS23540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A9498_RS23555	COG1104	cysteine desulfurase activity
A9498_RS23560	COG1959	2 iron, 2 sulfur cluster binding
A9498_RS23565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A9498_RS23575	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A9498_RS23600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A9498_RS23610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A9498_RS23610	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A9498_RS23615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A9498_RS23620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A9498_RS23620	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A9498_RS23630	COG2244	polysaccharide biosynthetic process
A9498_RS23635	COG2323	membrane
A9498_RS23650	COG1862	Preprotein translocase
A9498_RS23710	COG0157	Belongs to the NadC ModD family
A9498_RS23715	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A9498_RS23720	COG1104	cysteine desulfurase activity
A9498_RS23725	COG1827	regulation of RNA biosynthetic process
A9498_RS23730	COG2258	MOSC domain
A9498_RS23740	COG0077	Prephenate dehydratase
A9498_RS23745	COG0577	efflux transmembrane transporter activity
A9498_RS23750	COG0577	efflux transmembrane transporter activity
A9498_RS23755	COG1136	(ABC) transporter
A9498_RS23760	COG5002	protein histidine kinase activity
A9498_RS23765	COG0745	RESPONSE REGULATOR receiver
A9498_RS23775	COG3290	protein histidine kinase activity
A9498_RS23790	COG1530	ribonuclease E activity
A9498_RS23795	COG1994	Peptidase M50
A9498_RS23800	COG0739	heme binding
A9498_RS23805	COG2894	cell division
A9498_RS23825	COG1077	Cell shape determining protein MreB Mrl
A9498_RS23845	COG0285	dihydrofolate synthase activity
A9498_RS23860	COG1388	LysM domain
A9498_RS23870	COG0113	porphobilinogen synthase activity
A9498_RS23875	COG1587	Uroporphyrinogen-III synthase
A9498_RS23885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A9498_RS23895	COG1846	Transcriptional regulator
A9498_RS23900	COG1764	response to oxidative stress
A9498_RS23915	COG0470	DNA polymerase III
A9498_RS23915	COG1067	ATP-dependent peptidase activity
A9498_RS23960	COG0622	Phosphoesterase
A9498_RS23975	COG5401	PFAM Sporulation and spore germination
A9498_RS23990	COG2197	response regulator
A9498_RS23995	COG2233	PERMEase
A9498_RS24000	COG0402	S-adenosylhomocysteine deaminase activity
A9498_RS24005	COG1983	PspC domain protein
A9498_RS24010	COG1396	sequence-specific DNA binding
A9498_RS24015	COG0697	spore germination
A9498_RS24025	COG1959	2 iron, 2 sulfur cluster binding
A9498_RS24030	COG1668	transmembrane transport
A9498_RS24035	COG4152	abc transporter atp-binding protein
A9498_RS24040	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A9498_RS24050	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A9498_RS24055	COG1876	peptidase activity
A9498_RS24060	COG0824	Thioesterase
A9498_RS24065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A9498_RS24075	COG2009	succinate dehydrogenase
A9498_RS24080	COG1719	4-vinyl reductase, 4VR
A9498_RS24090	COG3118	belongs to the thioredoxin family
A9498_RS24095	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A9498_RS24100	COG2086	electron transfer activity
A9498_RS24105	COG1024	Enoyl-CoA hydratase
A9498_RS24110	COG1309	transcriptional regulator
A9498_RS24115	COG0318	PFAM AMP-dependent synthetase and ligase
A9498_RS24135	COG2318	DinB family
A9498_RS24160	COG1131	(ABC) transporter
A9498_RS24165	COG2205	protein histidine kinase activity
A9498_RS24170	COG0745	RESPONSE REGULATOR receiver
A9498_RS24175	COG4895	conserved protein (DUF2196)
A9498_RS24180	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A9498_RS24190	COG4509	Sortase family
A9498_RS24195	COG1120	ATPase activity
A9498_RS24210	COG5386	Cell surface protein
A9498_RS24220	COG5386	Cell surface protein
A9498_RS24225	COG1114	Component of the transport system for branched-chain amino acids
A9498_RS24230	COG1187	pseudouridine synthase activity
A9498_RS24240	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A9498_RS24240	COG1796	DNA polymerase
A9498_RS24245	COG1286	toxin biosynthetic process
A9498_RS24290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9498_RS24300	COG1418	mRNA catabolic process
A9498_RS24320	COG2814	Major facilitator Superfamily
A9498_RS24325	COG1566	PFAM secretion protein HlyD family protein
A9498_RS24330	COG1309	transcriptional regulator
A9498_RS24335	COG1363	Peptidase, m42
A9498_RS24360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A9498_RS24385	COG1484	DNA-dependent DNA replication
A9498_RS24390	COG3611	Membrane attachment protein
A9498_RS24400	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A9498_RS24405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A9498_RS24415	COG1971	Probably functions as a manganese efflux pump
A9498_RS24425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9498_RS24425	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9498_RS24430	COG5002	protein histidine kinase activity
A9498_RS24435	COG0745	RESPONSE REGULATOR receiver
A9498_RS24455	COG0538	isocitrate dehydrogenase activity
A9498_RS24460	COG0372	Belongs to the citrate synthase family
A9498_RS24475	COG0628	permease
A9498_RS24480	COG3030	protein affecting phage T7 exclusion by the F plasmid
A9498_RS24505	COG1725	Transcriptional regulator
A9498_RS24510	COG0281	malic enzyme
A9498_RS24515	COG0587	DNA-directed DNA polymerase activity
A9498_RS24530	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A9498_RS24545	COG4109	DRTGG domain
A9498_RS24555	COG0006	proline dipeptidase activity
A9498_RS24595	COG0662	Cupin 2, conserved barrel domain protein
A9498_RS24610	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS24615	COG0589	response to stress
A9498_RS24655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9498_RS24680	COG0827	DNA restriction-modification system
A9498_RS24685	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A9498_RS24690	COG3874	Sporulation protein YtfJ
A9498_RS24725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A9498_RS24740	COG1104	cysteine desulfurase activity
A9498_RS24750	COG0583	DNA-binding transcription factor activity
A9498_RS24755	COG0697	spore germination
A9498_RS24760	COG1309	transcriptional regulator
A9498_RS24765	COG1956	GAF domain-containing protein
A9498_RS24770	COG0626	cystathionine gamma-synthase activity
A9498_RS24905	COG0110	maltose O-acetyltransferase activity
A9498_RS24915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A9498_RS24920	COG0454	-acetyltransferase
A9498_RS24925	COG0517	IMP dehydrogenase activity
A9498_RS24930	COG0123	including yeast histone deacetylase and acetoin utilization protein
A9498_RS24945	COG0745	RESPONSE REGULATOR receiver
A9498_RS24950	COG5002	protein histidine kinase activity
A9498_RS24955	COG0666	response to abiotic stimulus
A9498_RS24980	COG1609	Transcriptional regulator
A9498_RS24985	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A9498_RS24985	COG1605	Chorismate mutase
A9498_RS24990	COG4851	CamS sex pheromone cAM373 precursor
A9498_RS24995	COG3118	belongs to the thioredoxin family
A9498_RS25005	COG2309	aminopeptidase activity
A9498_RS25020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9498_RS25025	COG0697	spore germination
A9498_RS25030	COG0789	Transcriptional regulator
A9498_RS25035	COG1695	Transcriptional regulator
A9498_RS25055	COG1674	ftsk spoiiie
A9498_RS25070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9498_RS25085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9498_RS25090	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
A9498_RS25095	COG1363	Peptidase, m42
A9498_RS25105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9498_RS25120	COG0510	thiamine kinase activity
A9498_RS25125	COG1523	belongs to the glycosyl hydrolase 13 family
A9498_RS25135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A9498_RS25140	COG1349	DNA-binding transcription factor activity
A9498_RS25145	COG1187	pseudouridine synthase activity
A9498_RS25150	COG2244	polysaccharide biosynthetic process
A9498_RS25155	COG2081	HI0933 family
A9498_RS25160	COG2814	Major facilitator Superfamily
A9498_RS25170	COG3832	glyoxalase III activity
A9498_RS25190	COG1329	Transcriptional regulator
A9498_RS25215	COG0314	molybdopterin synthase activity
A9498_RS25220	COG1763	Mo-molybdopterin cofactor biosynthetic process
A9498_RS25225	COG0303	'Molybdopterin
A9498_RS25235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A9498_RS25240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A9498_RS25265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9498_RS25275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A9498_RS25320	COG2814	Major facilitator Superfamily
A9498_RS25325	COG0475	glutathione-regulated potassium exporter activity
A9498_RS25330	COG0490	domain, Protein
A9498_RS25335	COG0582	viral genome integration into host DNA
A9498_RS25350	COG1136	(ABC) transporter
A9498_RS25370	COG1242	4 iron, 4 sulfur cluster binding
A9498_RS25375	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A9498_RS25380	COG1794	racemase activity, acting on amino acids and derivatives
A9498_RS25400	COG2267	carboxylic ester hydrolase activity
A9498_RS25405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A9498_RS25410	COG0671	phosphoesterase, PA-phosphatase related
A9498_RS25440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9498_RS25490	COG5002	protein histidine kinase activity
A9498_RS25495	COG3852	Histidine kinase
A9498_RS25500	COG2267	carboxylic ester hydrolase activity
A9498_RS25505	COG1368	sulfuric ester hydrolase activity
A9498_RS25530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A9498_RS25535	COG1116	anion transmembrane transporter activity
A9498_RS25540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A9498_RS25565	COG0494	nUDIX hydrolase
A9498_RS25595	COG1854	S-ribosylhomocysteine lyase activity
A9498_RS25605	COG0288	reversible hydration of carbon dioxide
A9498_RS25610	COG1271	oxidase subunit
A9498_RS25615	COG1294	oxidase, subunit
A9498_RS25630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9498_RS25650	COG1842	Phage shock protein A
A9498_RS25680	COG5002	protein histidine kinase activity
A9498_RS25685	COG0745	RESPONSE REGULATOR receiver
A9498_RS25710	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A9498_RS25715	COG1597	lipid kinase activity
A9498_RS25745	COG0586	Pfam SNARE associated Golgi protein
A9498_RS25755	COG0577	efflux transmembrane transporter activity
A9498_RS25760	COG1136	(ABC) transporter
A9498_RS25765	COG3708	Transcriptional regulator
A9498_RS25765	COG2207	Transcriptional regulator
A9498_RS25775	COG5658	integral membrane protein
A9498_RS25780	COG0640	Transcriptional regulator
A9498_RS25785	COG0745	RESPONSE REGULATOR receiver
A9498_RS25790	COG2205	protein histidine kinase activity
A9498_RS25795	COG0577	efflux transmembrane transporter activity
A9498_RS25800	COG0577	efflux transmembrane transporter activity
A9498_RS25805	COG1136	(ABC) transporter
A9498_RS25810	COG0577	efflux transmembrane transporter activity
A9498_RS25835	COG2188	Transcriptional regulator
A9498_RS25855	COG3964	amidohydrolase
A9498_RS25875	COG4948	Mandelate Racemase Muconate Lactonizing
A9498_RS25885	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A9498_RS25890	COG0596	Alpha beta hydrolase
A9498_RS25900	COG1169	isochorismate synthase
A9498_RS25905	COG1575	Belongs to the MenA family. Type 1 subfamily
A9498_RS25910	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A9498_RS25930	COG0058	SHG alpha-glucan phosphorylase activity
A9498_RS25940	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A9498_RS26065	COG0544	peptidyl-prolyl cis-trans isomerase activity
A9498_RS26100	COG1285	pathogenesis
A9498_RS26105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A9498_RS26125	COG2155	Conserved Protein
A9498_RS26130	COG1098	S1 RNA binding domain
A9498_RS26135	COG0436	Aminotransferase
A9498_RS26140	COG1522	sequence-specific DNA binding
A9498_RS26145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A9498_RS26150	COG2267	carboxylic ester hydrolase activity
A9498_RS26160	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A9498_RS26175	COG5018	Exonuclease
A9498_RS26180	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A9498_RS26200	COG2050	protein possibly involved in aromatic compounds catabolism
A9498_RS26210	COG1268	BioY protein
A9498_RS26215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A9498_RS26220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A9498_RS26235	COG3584	3D domain protein
A9498_RS26250	COG1252	NADH dehydrogenase
A9498_RS26265	COG3708	Transcriptional regulator
A9498_RS26280	COG1683	Conserved Protein
A9498_RS26295	COG0316	Belongs to the HesB IscA family
A9498_RS26310	COG1252	NADH dehydrogenase
A9498_RS26325	COG0390	transport system, permease component
A9498_RS26330	COG2824	Alkylphosphonate utilization operon protein PhnA
A9498_RS26360	COG4837	Protein of unknown function (DUF1462)
A9498_RS26365	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A9498_RS26375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A9498_RS26380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A9498_RS26400	COG1358	cellular component organization or biogenesis
A9498_RS26415	COG2249	NAD(P)H dehydrogenase (quinone) activity
A9498_RS26420	COG0647	UMP catabolic process
A9498_RS26430	COG2445	Protein of unknown function DUF86
A9498_RS26435	COG1494	fructose-1,6-bisphosphatase
A9498_RS26455	COG4470	Protein conserved in bacteria
A9498_RS26465	COG0789	Transcriptional regulator
A9498_RS26470	COG4377	Putative membrane peptidase family (DUF2324)
A9498_RS26495	COG0739	heme binding
A9498_RS26505	COG3377	Domain of unknown function (DUF1805)
A9498_RS26510	COG0737	Belongs to the 5'-nucleotidase family
A9498_RS26520	COG0719	Fe-S assembly protein
A9498_RS26525	COG0822	iron-sulfur transferase activity
A9498_RS26530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A9498_RS26535	COG0719	Fe-S assembly protein
A9498_RS26540	COG0396	ATPase activity
A9498_RS26545	COG1464	Belongs to the NlpA lipoprotein family
A9498_RS26550	COG1464	Belongs to the NlpA lipoprotein family
A9498_RS26555	COG2011	ABC-type metal ion transport system permease component
A9498_RS26570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9498_RS26575	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A9498_RS26585	COG1393	Belongs to the ArsC family
A9498_RS26605	COG0039	L-malate dehydrogenase activity
A9498_RS26625	COG1309	transcriptional regulator
A9498_RS26630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9498_RS26635	COG1960	acyl-CoA dehydrogenase activity
A9498_RS26640	COG0183	Belongs to the thiolase family
A9498_RS26645	COG1024	Enoyl-CoA hydratase
A9498_RS26645	COG1250	3-hydroxyacyl-CoA dehydrogenase
A9498_RS26655	COG1686	Belongs to the peptidase S11 family
A9498_RS26670	COG0011	TIGRFAM Protein of
A9498_RS26675	COG0840	transmembrane signaling receptor activity
A9498_RS26690	COG2814	Major facilitator Superfamily
A9498_RS26695	COG0531	amino acid
A9498_RS26715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9498_RS26755	COG0586	Pfam SNARE associated Golgi protein
A9498_RS26765	COG1376	ErfK ybiS ycfS ynhG family protein
A9498_RS26775	COG5002	protein histidine kinase activity
A9498_RS26810	COG0840	transmembrane signaling receptor activity
A9498_RS26815	COG2151	metal-sulfur cluster biosynthetic enzyme
A9498_RS26820	COG3227	Zinc metalloprotease (Elastase)
A9498_RS26825	COG1741	Belongs to the pirin family
A9498_RS26840	COG0586	Pfam SNARE associated Golgi protein
A9498_RS26845	COG0475	glutathione-regulated potassium exporter activity
A9498_RS26850	COG0490	domain, Protein
A9498_RS26855	COG1115	amino acid carrier protein
A9498_RS26860	COG0783	Belongs to the Dps family
A9498_RS26875	COG1611	Belongs to the LOG family
A9498_RS26885	COG1528	Iron-storage protein
A9498_RS26890	COG2311	Membrane
A9498_RS26895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A9498_RS26900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A9498_RS26905	COG1115	amino acid carrier protein
A9498_RS26910	COG1115	amino acid carrier protein
A9498_RS26915	COG2910	NAD(P)H-binding
A9498_RS26930	COG0656	L-ascorbic acid biosynthetic process
A9498_RS26935	COG2814	Major facilitator Superfamily
A9498_RS26940	COG1733	regulation of RNA biosynthetic process
A9498_RS26950	COG1252	NADH dehydrogenase
A9498_RS27005	COG0488	(ABC) transporter
A9498_RS27010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9498_RS27135	COG0557	exoribonuclease II activity
A9498_RS27145	COG0493	'glutamate synthase
A9498_RS27145	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
A9498_RS27165	COG3391	amine dehydrogenase activity
A9498_RS27170	COG5632	N-Acetylmuramoyl-L-alanine amidase
A9498_RS27295	COG0582	viral genome integration into host DNA
A9498_RS27385	COG0582	viral genome integration into host DNA
A9498_RS27390	COG1647	Serine aminopeptidase, S33
A9498_RS27395	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A9498_RS27400	COG1346	cytolysis
A9498_RS27435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A9498_RS27450	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A9498_RS27555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A9498_RS27570	COG2323	membrane
A9498_RS27580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9498_RS27590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A9498_RS27600	COG1051	belongs to the nudix hydrolase family
A9498_RS27610	COG0492	ferredoxin-NADP+ reductase activity
A9498_RS27615	COG0457	Tetratricopeptide repeat
A9498_RS27620	COG0110	maltose O-acetyltransferase activity
A9498_RS27640	COG1950	PFAM Membrane protein of
A9498_RS27650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A9498_RS27655	COG0556	nucleotide-excision repair
A9498_RS27670	COG0789	Transcriptional regulator
A9498_RS27690	COG0583	DNA-binding transcription factor activity
A9498_RS27700	COG0655	NAD(P)H dehydrogenase (quinone) activity
A9498_RS27705	COG0488	(ABC) transporter
A9498_RS27715	COG1132	(ABC) transporter
A9498_RS27720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A9498_RS27725	COG0793	Belongs to the peptidase S41A family
A9498_RS27725	COG3409	Peptidoglycan-binding domain 1 protein
A9498_RS27730	COG2177	Part of the ABC transporter FtsEX involved in
A9498_RS27735	COG2884	Cell division ATP-binding protein ftsE
A9498_RS27765	COG1131	(ABC) transporter
A9498_RS27795	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A9498_RS27800	COG1278	Cold shock
A9498_RS27805	COG1040	competence protein
A9498_RS27820	COG1733	regulation of RNA biosynthetic process
A9498_RS27825	COG1307	EDD domain protein, DegV family
A9498_RS27830	COG1739	Uncharacterized protein family UPF0029
A9498_RS27835	COG1316	TRANSCRIPTIONal
A9498_RS27845	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A9498_RS27850	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A9498_RS27855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A9498_RS27865	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A9498_RS27865	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A9498_RS27885	COG1486	melibiose metabolic process
A9498_RS27890	COG1447	Phosphotransferase system cellobiose-specific component IIA
A9498_RS27895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9498_RS27905	COG1447	Phosphotransferase system cellobiose-specific component IIA
A9498_RS27915	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9498_RS27920	COG1301	dicarboxylic acid transport
A9498_RS27935	COG1511	domain protein
A9498_RS27940	COG0583	DNA-binding transcription factor activity
A9498_RS27945	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A9498_RS27950	COG1271	oxidase subunit
A9498_RS27955	COG1294	oxidase, subunit
A9498_RS27960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A9498_RS27970	COG1620	l-lactate permease
A9498_RS27980	COG2389	metal-binding protein
A9498_RS27995	COG1368	sulfuric ester hydrolase activity
A9498_RS28020	COG1388	LysM domain
A9498_RS28020	COG0791	NLP P60 protein
A9498_RS28025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A9498_RS28035	COG1215	transferase activity, transferring glycosyl groups
A9498_RS28040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A9498_RS28050	COG1388	LysM domain
A9498_RS28050	COG3584	3D domain protein
A9498_RS28075	COG4715	Zinc finger, swim domain protein
A9498_RS28080	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A9498_RS28120	COG0577	efflux transmembrane transporter activity
A9498_RS28125	COG1136	(ABC) transporter
A9498_RS28160	COG5002	protein histidine kinase activity
A9498_RS28165	COG0745	RESPONSE REGULATOR receiver
A9498_RS28170	COG1482	cell wall glycoprotein biosynthetic process
A9498_RS28180	COG3711	transcriptional antiterminator
A9498_RS28180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9498_RS28185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A9498_RS28205	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
A9498_RS28205	COG0662	Cupin 2, conserved barrel domain protein
A9498_RS28220	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A9498_RS28225	COG1091	dTDP-4-dehydrorhamnose reductase activity
A9498_RS28240	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A9498_RS28265	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A9498_RS28270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A9498_RS28275	COG4464	protein tyrosine phosphatase activity
A9498_RS28280	COG0489	protein tyrosine kinase activity
A9498_RS28285	COG3944	biosynthesis protein
A9498_RS28290	COG0489	protein tyrosine kinase activity
A9498_RS28305	COG1609	Transcriptional regulator
A9498_RS28315	COG0739	heme binding
A9498_RS28330	COG3279	Response regulator of the LytR AlgR family
A9498_RS28335	COG2385	sporulation resulting in formation of a cellular spore
A9498_RS28350	COG4836	Membrane
A9498_RS28355	COG1007	ATP synthesis coupled electron transport
A9498_RS28360	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A9498_RS28365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A9498_RS28375	COG0839	Belongs to the complex I subunit 6 family
A9498_RS28395	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A9498_RS28410	COG5001	Diguanylate cyclase
A9498_RS28410	COG3300	MHYT domain
A9498_RS28460	COG0356	it plays a direct role in the translocation of protons across the membrane
A9498_RS28495	COG0698	ribose 5-phosphate isomerase
A9498_RS28510	COG2259	Doxx family
A9498_RS28515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A9498_RS28530	COG0009	L-threonylcarbamoyladenylate synthase
A9498_RS28565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A9498_RS28570	COG1494	fructose-1,6-bisphosphatase
A9498_RS28590	COG4821	SIS domain
A9498_RS28600	COG3343	RNA polymerase activity
A9498_RS28610	COG1960	acyl-CoA dehydrogenase activity
A9498_RS28615	COG1960	acyl-CoA dehydrogenase activity
A9498_RS28620	COG1250	3-hydroxyacyl-CoA dehydrogenase
A9498_RS28625	COG0183	Belongs to the thiolase family
A9498_RS28630	COG2181	nitrate reductase activity
A9498_RS28630	COG0247	lactate metabolic process
A9498_RS28635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9498_RS28665	COG2197	response regulator
A9498_RS28670	COG4585	Histidine kinase
A9498_RS28675	COG0842	Transport permease protein
A9498_RS28680	COG1131	(ABC) transporter
A9498_RS28685	COG0024	Methionine aminopeptidase
A9498_RS28695	COG2234	aminopeptidase activity
A9498_RS28720	COG1595	DNA-templated transcription, initiation
A9498_RS28730	COG4506	Protein conserved in bacteria
A9498_RS28735	COG1619	proteins homologs of microcin C7 resistance protein MccF
A9498_RS28760	COG2814	Major facilitator Superfamily
A9498_RS28765	COG0789	Transcriptional regulator
A9498_RS28770	COG0584	glycerophosphoryl diester phosphodiesterase
A9498_RS28775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9498_RS28785	COG1994	Peptidase M50
A9498_RS28795	COG1078	dGTPase activity
A9498_RS28800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A9498_RS28805	COG1120	ATPase activity
A9498_RS28810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9498_RS28815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9498_RS28835	COG0280	phosphate acetyltransferase
A9498_RS28850	COG3773	Cell wall hydrolase
A9498_RS28860	COG2363	Small membrane protein
A9498_RS28870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A9498_RS28875	COG2233	PERMEase
A9498_RS28880	COG0561	phosphatase activity
A9498_RS28885	COG2814	Major facilitator Superfamily
A9498_RS28895	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A9498_RS28900	COG1131	(ABC) transporter
A9498_RS28905	COG2755	lipolytic protein G-D-S-L family
A9498_RS28910	COG1609	Transcriptional regulator
A9498_RS28920	COG0460	homoserine dehydrogenase
A9498_RS28930	COG2873	o-acetylhomoserine
A9498_RS28940	COG1011	Hydrolase
A9498_RS28945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A9498_RS28955	COG2197	response regulator
A9498_RS28975	COG0351	phosphomethylpyrimidine kinase
A9498_RS28980	COG3706	GGDEF domain
A9498_RS28985	COG2879	small protein
A9498_RS28990	COG1966	Carbon starvation protein
A9498_RS28995	COG3279	Response regulator of the LytR AlgR family
A9498_RS29000	COG0477	Major facilitator Superfamily
A9498_RS29015	COG0438	transferase activity, transferring glycosyl groups
A9498_RS29030	COG0840	transmembrane signaling receptor activity
A9498_RS29040	COG1607	acyl-coa hydrolase
A9498_RS29045	COG1216	Glycosyl transferase, family 2
A9498_RS29060	COG1216	Glycosyl transferase, family 2
A9498_RS29070	COG4485	Bacterial membrane protein, YfhO
A9498_RS29075	COG0463	Glycosyl transferase, family 2
A9498_RS29080	COG0488	(ABC) transporter
A9498_RS29085	COG1309	transcriptional regulator
A9498_RS29090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9498_RS29095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9498_RS29095	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9498_RS29100	COG0628	permease
A9498_RS29120	COG3275	phosphorelay sensor kinase activity
A9498_RS29125	COG2814	Major facilitator Superfamily
A9498_RS29130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A9498_RS29135	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
A9498_RS29165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A9498_RS29170	COG1272	protein, Hemolysin III
A9498_RS29205	COG5002	protein histidine kinase activity
A9498_RS29285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A9498_RS29290	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A9498_RS29295	COG4853	Protein conserved in bacteria
A9498_RS29305	COG5002	protein histidine kinase activity
A9498_RS29310	COG0745	RESPONSE REGULATOR receiver
A9498_RS29340	COG0305	Participates in initiation and elongation during chromosome replication
A9498_RS29350	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A9498_RS29375	COG0012	GTP binding
A9498_RS29380	COG4481	Protein conserved in bacteria
A9498_RS29385	COG0668	transmembrane transport
A9498_RS29395	COG1475	DNA binding
A9498_RS29400	COG1192	Involved in chromosome partitioning
A9498_RS29425	COG1847	R3H domain protein
A9498_RS29440	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A9498_RS29545	COG2707	UPF0756 membrane protein
A9498_RS29555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A9498_RS29575	COG1114	Component of the transport system for branched-chain amino acids
A9498_RS29640	COG1136	(ABC) transporter
A9498_RS29660	COG1136	(ABC) transporter
A9498_RS29675	COG1136	(ABC) transporter
A9498_RS29680	COG0577	efflux transmembrane transporter activity
A9498_RS29690	COG1737	Transcriptional regulator
A9498_RS29695	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
A9498_RS29700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9498_RS29700	COG1263	PTS System
A9498_RS29700	COG2190	(PTS) system
A9498_RS29715	COG0741	lytic transglycosylase activity
A9498_RS29715	COG0791	NLP P60 protein
A9498_RS29775	COG1115	amino acid carrier protein
A9498_RS29780	COG4166	transmembrane transport
A9498_RS29800	COG1876	peptidase activity
A9498_RS29805	COG2843	Capsule synthesis protein
A9498_RS29820	COG3344	reverse transcriptase
A9498_RS29875	COG0697	spore germination
A9498_RS29895	COG2801	Transposase and inactivated derivatives
A9498_RS29925	COG3842	ATPase activity
A9498_RS29930	COG3250	beta-galactosidase activity
A9498_RS29935	COG1609	Transcriptional regulator
A9498_RS29945	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A9498_RS29950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A9498_RS29955	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A9498_RS29960	COG2182	Extracellular solute-binding protein
A9498_RS29970	COG0395	ABC-type sugar transport system, permease component
A9498_RS30035	COG1923	regulation of RNA biosynthetic process
A9498_RS30045	COG1114	Component of the transport system for branched-chain amino acids
A9498_RS30055	COG4166	transmembrane transport
A9498_RS30080	COG5002	protein histidine kinase activity
A9498_RS30090	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9498_RS30115	COG5002	protein histidine kinase activity
A9498_RS30140	COG3842	ATPase activity
A9498_RS30160	COG0395	ABC-type sugar transport system, permease component
A9498_RS30165	COG1175	transmembrane transport
A9498_RS30175	COG2814	Major facilitator Superfamily
A9498_RS30235	COG5002	protein histidine kinase activity
A9498_RS30240	COG0745	RESPONSE REGULATOR receiver
A9498_RS30360	COG0582	viral genome integration into host DNA
A9498_RS30365	COG2197	response regulator
A9498_RS30370	COG3344	reverse transcriptase
A9498_RS30470	COG2002	toxin-antitoxin pair type II binding
A9498_RS30480	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A9498_RS30490	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS30495	COG0277	FAD linked oxidase domain protein
A9498_RS30500	COG1070	Carbohydrate kinase
A9498_RS30540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A9498_RS30590	COG1999	signal sequence binding
A9498_RS30595	COG0662	Cupin 2, conserved barrel domain protein
A9498_RS30605	COG0010	Belongs to the arginase family
A9498_RS30615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9498_RS30625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9498_RS30630	COG0456	acetyltransferase
A9498_RS30675	COG3341	Caulimovirus viroplasmin
A9498_RS30675	COG0328	RNA-DNA hybrid ribonuclease activity
A9498_RS30695	COG4974	Belongs to the 'phage' integrase family
A9498_RS30705	COG0582	viral genome integration into host DNA
A9498_RS30730	COG0577	efflux transmembrane transporter activity
A9498_RS30730	COG1136	(ABC) transporter
A9498_RS30760	COG1725	Transcriptional regulator
A9498_RS30790	COG3011	Protein conserved in bacteria
A9498_RS30845	COG1301	dicarboxylic acid transport
A9498_RS30870	COG2801	Transposase and inactivated derivatives
A9498_RS30880	COG1923	regulation of RNA biosynthetic process
A9498_RS30920	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A9498_RS30925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A9498_RS30930	COG1535	isochorismatase
A9498_RS30930	COG3433	isochorismatase activity
A9498_RS30950	COG2801	Transposase and inactivated derivatives
A9498_RS30980	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS30990	COG1021	2,3-dihydroxybenzoate-AMP ligase
A9498_RS31040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A9498_RS31060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A9498_RS31070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A9498_RS31075	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
A9498_RS31085	COG0194	GDP metabolic process
A9498_RS31095	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS31100	COG1028	Short-chain dehydrogenase reductase Sdr
A9498_RS31105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A9498_RS31110	COG1260	myo-inositol-1-phosphate synthase
A9498_RS31145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A9498_RS31155	COG1199	ATP-dependent helicase activity
A9498_RS31180	COG0546	phosphoglycolate phosphatase activity
A9498_RS31210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A9498_RS31335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A9498_RS31415	COG3290	protein histidine kinase activity
A9498_RS31420	COG4565	transcriptional regulatory protein
A9498_RS31425	COG3493	citrate carrier protein
A9498_RS31470	COG1609	Transcriptional regulator
A9498_RS31475	COG2814	Major facilitator Superfamily
A9498_RS31480	COG0673	inositol 2-dehydrogenase activity
A9498_RS31510	COG3718	enzyme involved in inositol metabolism
A9498_RS31520	COG0840	transmembrane signaling receptor activity
A9498_RS31535	COG2002	toxin-antitoxin pair type II binding
A9498_RS31810	COG3397	chitin binding
A9498_RS32070	COG3250	beta-galactosidase activity
A9498_RS32095	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A9498_RS32105	COG3420	alginic acid biosynthetic process
A9498_RS32120	COG1923	regulation of RNA biosynthetic process
A9498_RS32225	COG2002	toxin-antitoxin pair type II binding
A9498_RS32330	COG3209	COG3209 Rhs family protein