locus-tag	class	description
BT4G5_RS00020	COG3880	PFAM UvrB UvrC protein
BT4G5_RS00030	COG0542	response to heat
BT4G5_RS00035	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BT4G5_RS00045	COG4956	integral membrane protein (PIN domain superfamily)
BT4G5_RS00065	COG1045	serine acetyltransferase
BT4G5_RS00080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BT4G5_RS00085	COG3688	RNA-binding protein containing a PIN domain
BT4G5_RS00100	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BT4G5_RS00105	COG0250	Participates in transcription elongation, termination and antitermination
BT4G5_RS00110	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BT4G5_RS00130	COG2813	Specifically methylates the guanine in position
BT4G5_RS00145	COG1358	cellular component organization or biogenesis
BT4G5_RS00150	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BT4G5_RS00215	COG0255	Belongs to the universal ribosomal protein uL29 family
BT4G5_RS00275	COG0201	protein transport
BT4G5_RS00285	COG0024	Methionine aminopeptidase
BT4G5_RS00295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BT4G5_RS00330	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BT4G5_RS00355	COG0860	N-Acetylmuramoyl-L-alanine amidase
BT4G5_RS00360	COG0489	protein tyrosine kinase activity
BT4G5_RS00370	COG2194	sulfuric ester hydrolase activity
BT4G5_RS00375	COG0726	polysaccharide deacetylase
BT4G5_RS00455	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BT4G5_RS00460	COG4856	YbbR-like protein
BT4G5_RS00495	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS00500	COG2011	ABC-type metal ion transport system permease component
BT4G5_RS00505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BT4G5_RS00510	COG1464	Belongs to the NlpA lipoprotein family
BT4G5_RS00515	COG0604	alcohol dehydrogenase
BT4G5_RS00525	COG0277	FAD linked oxidase domain protein
BT4G5_RS00530	COG2271	Major facilitator Superfamily
BT4G5_RS00540	COG2814	Major facilitator Superfamily
BT4G5_RS00560	COG2207	Transcriptional regulator
BT4G5_RS00575	COG4166	transmembrane transport
BT4G5_RS00580	COG4166	transmembrane transport
BT4G5_RS00585	COG0656	L-ascorbic acid biosynthetic process
BT4G5_RS00600	COG4149	molybdate abc transporter
BT4G5_RS00605	COG0725	ABC transporter, periplasmic molybdate-binding protein
BT4G5_RS00610	COG1910	domain protein
BT4G5_RS00630	COG0697	spore germination
BT4G5_RS00645	COG0204	Acyl-transferase
BT4G5_RS00655	COG1609	Transcriptional regulator
BT4G5_RS00665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT4G5_RS00680	COG2801	Transposase and inactivated derivatives
BT4G5_RS00695	COG5298	Protein conserved in bacteria
BT4G5_RS00720	COG0488	(ABC) transporter
BT4G5_RS00730	COG0747	negative chemotaxis
BT4G5_RS00735	COG0601	transmembrane transport
BT4G5_RS00740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BT4G5_RS00745	COG0444	Belongs to the ABC transporter superfamily
BT4G5_RS00750	COG4608	Belongs to the ABC transporter superfamily
BT4G5_RS00755	COG2801	Transposase and inactivated derivatives
BT4G5_RS00765	COG0561	phosphatase activity
BT4G5_RS00785	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BT4G5_RS00790	COG0179	Fumarylacetoacetate (FAA) hydrolase
BT4G5_RS00800	COG0531	amino acid
BT4G5_RS00805	COG2814	Major facilitator Superfamily
BT4G5_RS00815	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BT4G5_RS00825	COG4294	response to UV
BT4G5_RS00830	COG0705	Rhomboid family
BT4G5_RS00840	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BT4G5_RS00845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BT4G5_RS00850	COG0864	Transcriptional regulator
BT4G5_RS00855	COG2337	Toxic component of a toxin-antitoxin (TA) module
BT4G5_RS00860	COG2183	response to ionizing radiation
BT4G5_RS00960	COG0802	atpase or kinase
BT4G5_RS00965	COG1214	PFAM Peptidase M22, glycoprotease
BT4G5_RS00970	COG0456	acetyltransferase
BT4G5_RS00980	COG0488	(ABC) transporter
BT4G5_RS00995	COG1266	CAAX protease self-immunity
BT4G5_RS01015	COG0582	viral genome integration into host DNA
BT4G5_RS01150	COG0582	viral genome integration into host DNA
BT4G5_RS01250	COG4824	toxin secretion phage lysis holin
BT4G5_RS01270	COG2252	PERMEase
BT4G5_RS01280	COG5002	protein histidine kinase activity
BT4G5_RS01305	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BT4G5_RS01345	COG2205	protein histidine kinase activity
BT4G5_RS01350	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS01390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BT4G5_RS01400	COG0463	Glycosyl transferase, family 2
BT4G5_RS01400	COG1216	Glycosyl transferase, family 2
BT4G5_RS01420	COG0697	spore germination
BT4G5_RS01450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BT4G5_RS01455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BT4G5_RS01460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BT4G5_RS01470	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BT4G5_RS01485	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BT4G5_RS01495	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BT4G5_RS01505	COG0151	Belongs to the GarS family
BT4G5_RS01535	COG0210	DNA helicase
BT4G5_RS01545	COG4851	CamS sex pheromone cAM373 precursor
BT4G5_RS01560	COG1335	isochorismatase
BT4G5_RS01570	COG2011	ABC-type metal ion transport system permease component
BT4G5_RS01575	COG1464	Belongs to the NlpA lipoprotein family
BT4G5_RS01590	COG0003	Pfam Anion-transporting ATPase
BT4G5_RS01595	COG1846	Transcriptional regulator
BT4G5_RS01600	COG4682	membrane
BT4G5_RS01620	COG1597	lipid kinase activity
BT4G5_RS01630	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BT4G5_RS01640	COG1012	belongs to the aldehyde dehydrogenase family
BT4G5_RS01645	COG2076	Multidrug Resistance protein
BT4G5_RS01655	COG2309	aminopeptidase activity
BT4G5_RS01665	COG2801	Transposase and inactivated derivatives
BT4G5_RS01680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT4G5_RS01690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BT4G5_RS01695	COG4807	Protein conserved in bacteria
BT4G5_RS01725	COG1473	amidohydrolase
BT4G5_RS01740	COG0450	alkyl hydroperoxide reductase
BT4G5_RS01760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT4G5_RS01765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT4G5_RS01770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT4G5_RS01780	COG0492	ferredoxin-NADP+ reductase activity
BT4G5_RS01795	COG0166	Belongs to the GPI family
BT4G5_RS01820	COG5002	protein histidine kinase activity
BT4G5_RS01840	COG3541	Predicted nucleotidyltransferase
BT4G5_RS01845	COG2814	Major facilitator Superfamily
BT4G5_RS01850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BT4G5_RS01850	COG0723	plastoquinol--plastocyanin reductase activity
BT4G5_RS01860	COG0765	amino acid transport
BT4G5_RS01865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BT4G5_RS01875	COG0840	transmembrane signaling receptor activity
BT4G5_RS01900	COG0549	Belongs to the carbamate kinase family
BT4G5_RS01905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BT4G5_RS01920	COG0366	Alpha amylase catalytic
BT4G5_RS01925	COG2190	(PTS) system
BT4G5_RS01925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BT4G5_RS01925	COG1263	PTS System
BT4G5_RS01955	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BT4G5_RS01975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BT4G5_RS01985	COG1116	anion transmembrane transporter activity
BT4G5_RS02030	COG2270	Major facilitator Superfamily
BT4G5_RS02060	COG2310	stress, protein
BT4G5_RS02065	COG2310	stress, protein
BT4G5_RS02070	COG2310	stress, protein
BT4G5_RS02075	COG0861	Integral membrane protein TerC family
BT4G5_RS02085	COG3853	Toxic anion resistance protein (TelA)
BT4G5_RS02100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BT4G5_RS02110	COG1295	ribonuclease BN
BT4G5_RS02115	COG2217	Heavy metal translocating P-type atpase
BT4G5_RS02120	COG0697	spore germination
BT4G5_RS02140	COG0586	Pfam SNARE associated Golgi protein
BT4G5_RS02155	COG3871	stress protein (general stress protein 26)
BT4G5_RS02160	COG0387	Pfam Sodium calcium exchanger
BT4G5_RS02170	COG0535	radical SAM domain protein
BT4G5_RS02190	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BT4G5_RS02195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BT4G5_RS02210	COG3829	transcription factor binding
BT4G5_RS02220	COG0833	amino acid
BT4G5_RS02225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BT4G5_RS02260	COG1263	PTS System
BT4G5_RS02260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BT4G5_RS02265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BT4G5_RS02280	COG0463	Glycosyl transferase, family 2
BT4G5_RS02290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BT4G5_RS02290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BT4G5_RS02310	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BT4G5_RS02330	COG1228	amidohydrolase
BT4G5_RS02335	COG1090	epimerase
BT4G5_RS02365	COG1988	membrane-bound metal-dependent
BT4G5_RS02370	COG1194	a g-specific adenine glycosylase
BT4G5_RS02395	COG1132	(ABC) transporter
BT4G5_RS02400	COG4129	membrane
BT4G5_RS02405	COG0067	glutamate synthase
BT4G5_RS02405	COG0069	glutamate synthase activity
BT4G5_RS02405	COG0070	glutamate synthase
BT4G5_RS02415	COG4555	ABC transporter
BT4G5_RS02435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BT4G5_RS02440	COG0735	belongs to the Fur family
BT4G5_RS02560	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BT4G5_RS02585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BT4G5_RS02590	COG1716	ATPase activity
BT4G5_RS02590	COG5001	Diguanylate cyclase
BT4G5_RS02600	COG2766	serine protein kinase
BT4G5_RS02620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BT4G5_RS02630	COG1585	Membrane protein implicated in regulation of membrane protease activity
BT4G5_RS02635	COG2268	Band 7 protein
BT4G5_RS02645	COG3290	protein histidine kinase activity
BT4G5_RS02650	COG4565	transcriptional regulatory protein
BT4G5_RS02655	COG2851	Citrate transporter
BT4G5_RS02680	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BT4G5_RS02685	COG3842	ATPase activity
BT4G5_RS02690	COG1175	transmembrane transport
BT4G5_RS02695	COG0395	ABC-type sugar transport system, permease component
BT4G5_RS02705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BT4G5_RS02710	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS02715	COG3850	Histidine kinase
BT4G5_RS02715	COG5002	protein histidine kinase activity
BT4G5_RS02725	COG4990	cell redox homeostasis
BT4G5_RS02735	COG3290	protein histidine kinase activity
BT4G5_RS02740	COG4565	transcriptional regulatory protein
BT4G5_RS02745	COG3493	citrate carrier protein
BT4G5_RS02750	COG0281	malic enzyme
BT4G5_RS02760	COG0697	spore germination
BT4G5_RS02765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT4G5_RS02775	COG5002	protein histidine kinase activity
BT4G5_RS02780	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS02795	COG0456	acetyltransferase
BT4G5_RS02795	COG0454	-acetyltransferase
BT4G5_RS02800	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BT4G5_RS02805	COG3383	formate dehydrogenase (NAD+) activity
BT4G5_RS02810	COG2427	Protein of unknown function (DUF1641)
BT4G5_RS02825	COG0531	amino acid
BT4G5_RS02835	COG0640	Transcriptional regulator
BT4G5_RS02840	COG2217	Heavy metal translocating P-type atpase
BT4G5_RS02850	COG2801	Transposase and inactivated derivatives
BT4G5_RS02855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BT4G5_RS02870	COG3227	Zinc metalloprotease (Elastase)
BT4G5_RS02890	COG2720	vancomycin resistance protein
BT4G5_RS02895	COG1316	TRANSCRIPTIONal
BT4G5_RS02900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT4G5_RS02905	COG0346	lactoylglutathione lyase activity
BT4G5_RS02910	COG1253	flavin adenine dinucleotide binding
BT4G5_RS02915	COG1027	Aspartate ammonia-lyase
BT4G5_RS02920	COG1620	l-lactate permease
BT4G5_RS02935	COG3104	oligopeptide transport
BT4G5_RS02940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT4G5_RS02945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT4G5_RS02950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT4G5_RS02960	COG2226	methyltransferase
BT4G5_RS02970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BT4G5_RS02980	COG4548	von Willebrand factor, type A
BT4G5_RS02985	COG0714	Associated with various cellular activities
BT4G5_RS03005	COG0531	amino acid
BT4G5_RS03010	COG2188	Transcriptional regulator
BT4G5_RS03015	COG1263	PTS System
BT4G5_RS03015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BT4G5_RS03020	COG0366	Alpha amylase catalytic
BT4G5_RS03035	COG0697	spore germination
BT4G5_RS03040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BT4G5_RS03045	COG1115	amino acid carrier protein
BT4G5_RS03055	COG1126	abc transporter atp-binding protein
BT4G5_RS03060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BT4G5_RS03065	COG0765	amino acid transport
BT4G5_RS03070	COG0765	amino acid transport
BT4G5_RS03075	COG0833	amino acid
BT4G5_RS03090	COG1595	DNA-templated transcription, initiation
BT4G5_RS03100	COG2378	regulation of single-species biofilm formation
BT4G5_RS03105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BT4G5_RS03110	COG5002	protein histidine kinase activity
BT4G5_RS03140	COG2271	Major facilitator Superfamily
BT4G5_RS03145	COG1846	Transcriptional regulator
BT4G5_RS03150	COG0477	Major facilitator Superfamily
BT4G5_RS03155	COG1609	Transcriptional regulator
BT4G5_RS03160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BT4G5_RS03175	COG1172	Belongs to the binding-protein-dependent transport system permease family
BT4G5_RS03180	COG1879	ABC-type sugar transport system periplasmic component
BT4G5_RS03210	COG1063	alcohol dehydrogenase
BT4G5_RS03260	COG0840	transmembrane signaling receptor activity
BT4G5_RS03265	COG3584	3D domain protein
BT4G5_RS03265	COG3583	domain protein
BT4G5_RS03270	COG1476	TRANSCRIPTIONal
BT4G5_RS03290	COG3104	oligopeptide transport
BT4G5_RS03295	COG1114	Component of the transport system for branched-chain amino acids
BT4G5_RS03310	COG1113	amino acid transport
BT4G5_RS03315	COG2252	PERMEase
BT4G5_RS03330	COG2153	protein acetylation
BT4G5_RS03340	COG0475	glutathione-regulated potassium exporter activity
BT4G5_RS03340	COG0569	domain protein
BT4G5_RS03350	COG1845	cytochrome c oxidase, subunit III
BT4G5_RS03355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BT4G5_RS03365	COG0833	amino acid
BT4G5_RS03370	COG4990	cell redox homeostasis
BT4G5_RS03385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BT4G5_RS03390	COG0697	spore germination
BT4G5_RS03395	COG0531	amino acid
BT4G5_RS03410	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BT4G5_RS03415	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BT4G5_RS03420	COG1918	ferrous iron import across plasma membrane
BT4G5_RS03420	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BT4G5_RS03425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BT4G5_RS03430	COG0573	inorganic phosphate transmembrane transporter activity
BT4G5_RS03435	COG0581	inorganic phosphate transmembrane transporter activity
BT4G5_RS03440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BT4G5_RS03535	COG4974	Belongs to the 'phage' integrase family
BT4G5_RS03560	COG0582	viral genome integration into host DNA
BT4G5_RS03620	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BT4G5_RS03655	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BT4G5_RS03660	COG5001	Diguanylate cyclase
BT4G5_RS03660	COG1716	ATPase activity
BT4G5_RS03670	COG2766	serine protein kinase
BT4G5_RS03685	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BT4G5_RS03695	COG1585	Membrane protein implicated in regulation of membrane protease activity
BT4G5_RS03700	COG2268	Band 7 protein
BT4G5_RS03710	COG3290	protein histidine kinase activity
BT4G5_RS03715	COG4565	transcriptional regulatory protein
BT4G5_RS03720	COG2851	Citrate transporter
BT4G5_RS03745	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BT4G5_RS03750	COG3842	ATPase activity
BT4G5_RS03755	COG1175	transmembrane transport
BT4G5_RS03760	COG0395	ABC-type sugar transport system, permease component
BT4G5_RS03770	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BT4G5_RS03775	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS03780	COG5002	protein histidine kinase activity
BT4G5_RS03780	COG3850	Histidine kinase
BT4G5_RS03790	COG4990	cell redox homeostasis
BT4G5_RS03800	COG3290	protein histidine kinase activity
BT4G5_RS03805	COG4565	transcriptional regulatory protein
BT4G5_RS03810	COG3493	citrate carrier protein
BT4G5_RS03815	COG0281	malic enzyme
BT4G5_RS03825	COG0697	spore germination
BT4G5_RS03830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT4G5_RS03840	COG5002	protein histidine kinase activity
BT4G5_RS03845	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS03860	COG0454	-acetyltransferase
BT4G5_RS03860	COG0456	acetyltransferase
BT4G5_RS03865	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BT4G5_RS03870	COG3383	formate dehydrogenase (NAD+) activity
BT4G5_RS03875	COG2427	Protein of unknown function (DUF1641)
BT4G5_RS03900	COG0640	Transcriptional regulator
BT4G5_RS03905	COG2217	Heavy metal translocating P-type atpase
BT4G5_RS03910	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BT4G5_RS03925	COG3227	Zinc metalloprotease (Elastase)
BT4G5_RS03945	COG2720	vancomycin resistance protein
BT4G5_RS03950	COG1316	TRANSCRIPTIONal
BT4G5_RS03955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT4G5_RS03960	COG0346	lactoylglutathione lyase activity
BT4G5_RS03965	COG1253	flavin adenine dinucleotide binding
BT4G5_RS03970	COG1027	Aspartate ammonia-lyase
BT4G5_RS03975	COG1620	l-lactate permease
BT4G5_RS03990	COG3104	oligopeptide transport
BT4G5_RS03995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT4G5_RS04000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT4G5_RS04005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT4G5_RS04015	COG2226	methyltransferase
BT4G5_RS04025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BT4G5_RS04035	COG4548	von Willebrand factor, type A
BT4G5_RS04040	COG0714	Associated with various cellular activities
BT4G5_RS04060	COG0531	amino acid
BT4G5_RS04065	COG2188	Transcriptional regulator
BT4G5_RS04070	COG1263	PTS System
BT4G5_RS04070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BT4G5_RS04075	COG0366	Alpha amylase catalytic
BT4G5_RS04090	COG0697	spore germination
BT4G5_RS04095	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BT4G5_RS04100	COG1115	amino acid carrier protein
BT4G5_RS04110	COG1126	abc transporter atp-binding protein
BT4G5_RS04115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BT4G5_RS04120	COG0765	amino acid transport
BT4G5_RS04125	COG0765	amino acid transport
BT4G5_RS04130	COG0833	amino acid
BT4G5_RS04145	COG1595	DNA-templated transcription, initiation
BT4G5_RS04155	COG2378	regulation of single-species biofilm formation
BT4G5_RS04160	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BT4G5_RS04165	COG5002	protein histidine kinase activity
BT4G5_RS04195	COG2271	Major facilitator Superfamily
BT4G5_RS04205	COG2271	Major facilitator Superfamily
BT4G5_RS04210	COG1846	Transcriptional regulator
BT4G5_RS04215	COG0477	Major facilitator Superfamily
BT4G5_RS04220	COG1609	Transcriptional regulator
BT4G5_RS04225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BT4G5_RS04240	COG1172	Belongs to the binding-protein-dependent transport system permease family
BT4G5_RS04245	COG1879	ABC-type sugar transport system periplasmic component
BT4G5_RS04275	COG1063	alcohol dehydrogenase
BT4G5_RS04285	COG2801	Transposase and inactivated derivatives
BT4G5_RS04315	COG1396	sequence-specific DNA binding
BT4G5_RS04400	COG3331	DNA recombination
BT4G5_RS04455	COG5484	DNA packaging
BT4G5_RS04455	COG3728	DNA packaging
BT4G5_RS04575	COG1674	ftsk spoiiie
BT4G5_RS04620	COG0840	transmembrane signaling receptor activity
BT4G5_RS04625	COG3583	domain protein
BT4G5_RS04625	COG3584	3D domain protein
BT4G5_RS04630	COG1476	TRANSCRIPTIONal
BT4G5_RS04650	COG3104	oligopeptide transport
BT4G5_RS04655	COG1114	Component of the transport system for branched-chain amino acids
BT4G5_RS04670	COG1113	amino acid transport
BT4G5_RS04675	COG2252	PERMEase
BT4G5_RS04690	COG2153	protein acetylation
BT4G5_RS04700	COG0569	domain protein
BT4G5_RS04700	COG0475	glutathione-regulated potassium exporter activity
BT4G5_RS04710	COG1845	cytochrome c oxidase, subunit III
BT4G5_RS04715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BT4G5_RS04725	COG0833	amino acid
BT4G5_RS04730	COG4990	cell redox homeostasis
BT4G5_RS04745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BT4G5_RS04750	COG0697	spore germination
BT4G5_RS04755	COG0531	amino acid
BT4G5_RS04770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BT4G5_RS04775	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BT4G5_RS04780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BT4G5_RS04780	COG1918	ferrous iron import across plasma membrane
BT4G5_RS04785	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BT4G5_RS04790	COG0573	inorganic phosphate transmembrane transporter activity
BT4G5_RS04795	COG0581	inorganic phosphate transmembrane transporter activity
BT4G5_RS04800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BT4G5_RS04920	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BT4G5_RS04945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BT4G5_RS04950	COG1116	anion transmembrane transporter activity
BT4G5_RS04955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BT4G5_RS04960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BT4G5_RS04965	COG0352	thiamine-phosphate diphosphorylase activity
BT4G5_RS04970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BT4G5_RS04975	COG2104	thiamine diphosphate biosynthetic process
BT4G5_RS04985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BT4G5_RS04990	COG0351	phosphomethylpyrimidine kinase
BT4G5_RS05030	COG2205	protein histidine kinase activity
BT4G5_RS05035	COG2814	Major facilitator Superfamily
BT4G5_RS05040	COG1846	Transcriptional regulator
BT4G5_RS05065	COG1136	(ABC) transporter
BT4G5_RS05075	COG2252	PERMEase
BT4G5_RS05080	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS05140	COG0778	Nitroreductase
BT4G5_RS05145	COG2719	SpoVR family
BT4G5_RS05155	COG3591	Belongs to the peptidase S1B family
BT4G5_RS05165	COG0446	pyridine nucleotide-disulphide oxidoreductase
BT4G5_RS05170	COG1937	Protein conserved in bacteria
BT4G5_RS05175	COG0425	Belongs to the sulfur carrier protein TusA family
BT4G5_RS05175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BT4G5_RS05180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT4G5_RS05180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BT4G5_RS05185	COG0425	Belongs to the sulfur carrier protein TusA family
BT4G5_RS05200	COG2210	Belongs to the sulfur carrier protein TusA family
BT4G5_RS05205	COG0730	response to heat
BT4G5_RS05215	COG1316	TRANSCRIPTIONal
BT4G5_RS05220	COG0604	alcohol dehydrogenase
BT4G5_RS05225	COG1283	sodium-dependent phosphate transmembrane transporter activity
BT4G5_RS05240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BT4G5_RS05240	COG3711	transcriptional antiterminator
BT4G5_RS05245	COG1447	Phosphotransferase system cellobiose-specific component IIA
BT4G5_RS05250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BT4G5_RS05275	COG1388	LysM domain
BT4G5_RS05275	COG3584	3D domain protein
BT4G5_RS05280	COG0577	efflux transmembrane transporter activity
BT4G5_RS05285	COG1136	(ABC) transporter
BT4G5_RS05295	COG5522	Integral membrane protein (intg_mem_TP0381)
BT4G5_RS05310	COG1114	Component of the transport system for branched-chain amino acids
BT4G5_RS05315	COG3546	catalase activity
BT4G5_RS05350	COG0586	Pfam SNARE associated Golgi protein
BT4G5_RS05385	COG0531	amino acid
BT4G5_RS05390	COG0475	glutathione-regulated potassium exporter activity
BT4G5_RS05400	COG1737	Transcriptional regulator
BT4G5_RS05410	COG1263	PTS System
BT4G5_RS05410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BT4G5_RS05420	COG2259	Doxx family
BT4G5_RS05440	COG1522	sequence-specific DNA binding
BT4G5_RS05445	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BT4G5_RS05445	COG0165	Argininosuccinate lyase
BT4G5_RS05450	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS05470	COG1309	transcriptional regulator
BT4G5_RS05475	COG2814	Major facilitator Superfamily
BT4G5_RS05480	COG1733	regulation of RNA biosynthetic process
BT4G5_RS05495	COG4533	DNA binding
BT4G5_RS05500	COG2211	Major facilitator Superfamily
BT4G5_RS05510	COG0693	protein deglycase activity
BT4G5_RS05515	COG0753	catalase activity
BT4G5_RS05525	COG0531	amino acid
BT4G5_RS05540	COG1012	belongs to the aldehyde dehydrogenase family
BT4G5_RS05550	COG1132	(ABC) transporter
BT4G5_RS05555	COG1132	(ABC) transporter
BT4G5_RS05560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BT4G5_RS05565	COG0765	amino acid transport
BT4G5_RS05570	COG1126	abc transporter atp-binding protein
BT4G5_RS05585	COG0189	ligase activity
BT4G5_RS05615	COG0028	Belongs to the TPP enzyme family
BT4G5_RS05620	COG3527	Alpha-acetolactate decarboxylase
BT4G5_RS05635	COG0561	phosphatase activity
BT4G5_RS05645	COG3409	Peptidoglycan-binding domain 1 protein
BT4G5_RS05645	COG5632	N-Acetylmuramoyl-L-alanine amidase
BT4G5_RS05650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BT4G5_RS05655	COG0318	PFAM AMP-dependent synthetase and ligase
BT4G5_RS05670	COG0659	secondary active sulfate transmembrane transporter activity
BT4G5_RS05675	COG2244	polysaccharide biosynthetic process
BT4G5_RS05695	COG1024	Enoyl-CoA hydratase
BT4G5_RS05715	COG1363	Peptidase, m42
BT4G5_RS05755	COG0601	transmembrane transport
BT4G5_RS05760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BT4G5_RS05765	COG0444	Belongs to the ABC transporter superfamily
BT4G5_RS05770	COG4608	Belongs to the ABC transporter superfamily
BT4G5_RS05785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT4G5_RS05875	COG0477	Major facilitator Superfamily
BT4G5_RS05880	COG3290	protein histidine kinase activity
BT4G5_RS05885	COG4565	transcriptional regulatory protein
BT4G5_RS05890	COG3181	Tripartite tricarboxylate transporter family receptor
BT4G5_RS05895	COG0494	nUDIX hydrolase
BT4G5_RS05910	COG0305	Participates in initiation and elongation during chromosome replication
BT4G5_RS05930	COG2801	Transposase and inactivated derivatives
BT4G5_RS05935	COG2801	Transposase and inactivated derivatives
BT4G5_RS05950	COG2801	Transposase and inactivated derivatives
BT4G5_RS05955	COG0305	Participates in initiation and elongation during chromosome replication
BT4G5_RS05980	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BT4G5_RS05985	COG1288	antiporter activity
BT4G5_RS05995	COG1842	Phage shock protein A
BT4G5_RS06005	COG0477	Major facilitator Superfamily
BT4G5_RS06020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS06035	COG2801	Transposase and inactivated derivatives
BT4G5_RS06075	COG2020	methyltransferase activity
BT4G5_RS06100	COG1073	alpha beta
BT4G5_RS06110	COG2801	Transposase and inactivated derivatives
BT4G5_RS06135	COG0577	efflux transmembrane transporter activity
BT4G5_RS06150	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BT4G5_RS06155	COG1522	sequence-specific DNA binding
BT4G5_RS06170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BT4G5_RS06225	COG1183	phosphatidylcholine synthase activity
BT4G5_RS06235	COG2814	Major facilitator Superfamily
BT4G5_RS06240	COG0640	Transcriptional regulator
BT4G5_RS06265	COG2376	Dihydroxyacetone kinase
BT4G5_RS06310	COG2373	Large extracellular alpha-helical protein
BT4G5_RS06385	COG1191	sigma factor activity
BT4G5_RS06395	COG2208	phosphoserine phosphatase activity
BT4G5_RS06400	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BT4G5_RS06405	COG5002	protein histidine kinase activity
BT4G5_RS06405	COG0784	Response regulator, receiver
BT4G5_RS06405	COG2205	protein histidine kinase activity
BT4G5_RS06440	COG2807	transmembrane transport
BT4G5_RS06445	COG2186	Transcriptional regulator
BT4G5_RS06455	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BT4G5_RS06475	COG0420	3'-5' exonuclease activity
BT4G5_RS06480	COG4717	serine-type aminopeptidase activity
BT4G5_RS06490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BT4G5_RS06505	COG0346	lactoylglutathione lyase activity
BT4G5_RS06510	COG0346	lactoylglutathione lyase activity
BT4G5_RS06515	COG0457	Tetratricopeptide repeat
BT4G5_RS06525	COG2267	carboxylic ester hydrolase activity
BT4G5_RS06540	COG2140	Oxalate decarboxylase
BT4G5_RS06545	COG3620	sequence-specific DNA binding
BT4G5_RS06550	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BT4G5_RS06555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BT4G5_RS06565	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BT4G5_RS06580	COG1595	DNA-templated transcription, initiation
BT4G5_RS06590	COG0772	Belongs to the SEDS family
BT4G5_RS06595	COG3973	AAA domain
BT4G5_RS06625	COG4980	gas vesicle protein
BT4G5_RS06630	COG0537	adenosine 5'-monophosphoramidase activity
BT4G5_RS06635	COG1131	(ABC) transporter
BT4G5_RS06640	COG4473	ABC transporter
BT4G5_RS06650	COG1309	transcriptional regulator
BT4G5_RS06660	COG3402	PFAM membrane-flanked domain
BT4G5_RS06665	COG3428	Bacterial PH domain
BT4G5_RS06700	COG0697	spore germination
BT4G5_RS06705	COG3402	PFAM membrane-flanked domain
BT4G5_RS06710	COG3428	Bacterial PH domain
BT4G5_RS06715	COG2329	Antibiotic biosynthesis monooxygenase
BT4G5_RS06720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BT4G5_RS06735	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BT4G5_RS06770	COG1484	DNA-dependent DNA replication
BT4G5_RS06785	COG1309	transcriptional regulator
BT4G5_RS06820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS06825	COG1609	Transcriptional regulator
BT4G5_RS06835	COG1234	tRNA 3'-trailer cleavage
BT4G5_RS06840	COG0095	Lipoate-protein ligase
BT4G5_RS06855	COG0318	PFAM AMP-dependent synthetase and ligase
BT4G5_RS06865	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BT4G5_RS06875	COG4208	sulfate ABC transporter
BT4G5_RS06960	COG1309	transcriptional regulator
BT4G5_RS06965	COG1073	alpha beta
BT4G5_RS06970	COG1408	metallophosphoesterase
BT4G5_RS06975	COG1078	dGTPase activity
BT4G5_RS06985	COG1595	DNA-templated transcription, initiation
BT4G5_RS06990	COG3708	Transcriptional regulator
BT4G5_RS06990	COG2207	Transcriptional regulator
BT4G5_RS07000	COG2205	protein histidine kinase activity
BT4G5_RS07005	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS07025	COG0501	Belongs to the peptidase M48B family
BT4G5_RS07030	COG0840	transmembrane signaling receptor activity
BT4G5_RS07035	COG3693	PFAM glycoside hydrolase, family 10
BT4G5_RS07045	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BT4G5_RS07050	COG2224	Isocitrate lyase
BT4G5_RS07065	COG1278	Cold shock
BT4G5_RS07085	COG0398	Pfam SNARE associated Golgi protein
BT4G5_RS07145	COG0179	Fumarylacetoacetate (FAA) hydrolase
BT4G5_RS07170	COG0367	asparagine synthase
BT4G5_RS07180	COG0753	catalase activity
BT4G5_RS07190	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BT4G5_RS07215	COG3339	Conserved Protein
BT4G5_RS07220	COG0004	ammonium transporteR
BT4G5_RS07240	COG2996	Protein conserved in bacteria
BT4G5_RS07265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT4G5_RS07280	COG0561	phosphatase activity
BT4G5_RS07300	COG2267	carboxylic ester hydrolase activity
BT4G5_RS07315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BT4G5_RS07320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BT4G5_RS07325	COG5504	Zn-dependent protease
BT4G5_RS07340	COG0180	Tryptophanyl-tRNA synthetase
BT4G5_RS07355	COG4166	transmembrane transport
BT4G5_RS07360	COG0601	transmembrane transport
BT4G5_RS07365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BT4G5_RS07370	COG0444	Belongs to the ABC transporter superfamily
BT4G5_RS07375	COG4608	Belongs to the ABC transporter superfamily
BT4G5_RS07380	COG0534	Mate efflux family protein
BT4G5_RS07385	COG4166	transmembrane transport
BT4G5_RS07405	COG0861	Integral membrane protein TerC family
BT4G5_RS07415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BT4G5_RS07425	COG1164	Oligoendopeptidase f
BT4G5_RS07440	COG2346	COG2346, Truncated hemoglobins
BT4G5_RS07445	COG4116	CYTH
BT4G5_RS07455	COG2357	RelA SpoT domain protein
BT4G5_RS07465	COG0564	pseudouridine synthase activity
BT4G5_RS07480	COG0772	Belongs to the SEDS family
BT4G5_RS07485	COG1216	Glycosyl transferase, family 2
BT4G5_RS07505	COG0457	Tetratricopeptide repeat
BT4G5_RS07505	COG0463	Glycosyl transferase, family 2
BT4G5_RS07525	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BT4G5_RS07540	COG1091	dTDP-4-dehydrorhamnose reductase activity
BT4G5_RS07585	COG2153	protein acetylation
BT4G5_RS07595	COG2382	esterase
BT4G5_RS07620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BT4G5_RS07635	COG0512	Glutamine amidotransferase of anthranilate synthase
BT4G5_RS07635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BT4G5_RS07670	COG1620	l-lactate permease
BT4G5_RS07675	COG5634	Uncharacterized conserved protein (DUF2278)
BT4G5_RS07715	COG2226	methyltransferase
BT4G5_RS07735	COG0508	dehydrogenase complex catalyzes the overall conversion of
BT4G5_RS07745	COG1476	TRANSCRIPTIONal
BT4G5_RS07780	COG2801	Transposase and inactivated derivatives
BT4G5_RS07795	COG4152	abc transporter atp-binding protein
BT4G5_RS07800	COG1668	transmembrane transport
BT4G5_RS07820	COG2226	methyltransferase
BT4G5_RS07830	COG1686	Belongs to the peptidase S11 family
BT4G5_RS07835	COG0681	Belongs to the peptidase S26 family
BT4G5_RS07870	COG1012	belongs to the aldehyde dehydrogenase family
BT4G5_RS07880	COG1176	ABC-type spermidine putrescine transport system, permease component I
BT4G5_RS07885	COG1177	transmembrane transport
BT4G5_RS07900	COG2409	Drug exporters of the RND superfamily
BT4G5_RS07910	COG0564	pseudouridine synthase activity
BT4G5_RS07920	COG2340	Cysteine-rich secretory protein family
BT4G5_RS07925	COG0247	lactate metabolic process
BT4G5_RS07930	COG0277	FAD linked oxidase domain protein
BT4G5_RS07935	COG3835	regulator
BT4G5_RS07945	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS07950	COG5002	protein histidine kinase activity
BT4G5_RS07955	COG2186	Transcriptional regulator
BT4G5_RS07975	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BT4G5_RS07985	COG2116	formate transmembrane transporter activity
BT4G5_RS07990	COG0861	Integral membrane protein TerC family
BT4G5_RS07995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BT4G5_RS08005	COG2030	dehydratase
BT4G5_RS08025	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS08030	COG3243	poly(R)-hydroxyalkanoic acid synthase
BT4G5_RS08040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BT4G5_RS08055	COG1840	ABC-type Fe3 transport system, periplasmic component
BT4G5_RS08060	COG3842	ATPase activity
BT4G5_RS08085	COG1349	DNA-binding transcription factor activity
BT4G5_RS08100	COG0235	Class ii aldolase
BT4G5_RS08110	COG2861	carbohydrate metabolic process
BT4G5_RS08120	COG3852	Histidine kinase
BT4G5_RS08125	COG1846	Transcriptional regulator
BT4G5_RS08135	COG2318	DinB family
BT4G5_RS08145	COG5002	protein histidine kinase activity
BT4G5_RS08155	COG0720	synthase
BT4G5_RS08170	COG4873	Protein conserved in bacteria
BT4G5_RS08210	COG1780	Probably involved in ribonucleotide reductase function
BT4G5_RS08215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BT4G5_RS08220	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BT4G5_RS08225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BT4G5_RS08230	COG1725	Transcriptional regulator
BT4G5_RS08235	COG1131	(ABC) transporter
BT4G5_RS08245	COG1131	(ABC) transporter
BT4G5_RS08265	COG1522	sequence-specific DNA binding
BT4G5_RS08275	COG1335	isochorismatase
BT4G5_RS08285	COG1619	proteins homologs of microcin C7 resistance protein MccF
BT4G5_RS08290	COG2070	2-Nitropropane dioxygenase
BT4G5_RS08295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BT4G5_RS08305	COG1696	Membrane protein involved in D-alanine export
BT4G5_RS08330	COG0716	FMN binding
BT4G5_RS08380	COG1846	Transcriptional regulator
BT4G5_RS08390	COG1301	dicarboxylic acid transport
BT4G5_RS08395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BT4G5_RS08400	COG4709	membrane
BT4G5_RS08405	COG3874	Sporulation protein YtfJ
BT4G5_RS08435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BT4G5_RS08440	COG0028	Belongs to the TPP enzyme family
BT4G5_RS08445	COG0440	acetolactate synthase activity
BT4G5_RS08520	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BT4G5_RS08535	COG1183	phosphatidylcholine synthase activity
BT4G5_RS08540	COG1368	sulfuric ester hydrolase activity
BT4G5_RS08550	COG0019	diaminopimelate decarboxylase activity
BT4G5_RS08570	COG0529	Catalyzes the synthesis of activated sulfate
BT4G5_RS08575	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BT4G5_RS08595	COG1648	precorrin-2 dehydrogenase activity
BT4G5_RS08605	COG0733	neurotransmitter:sodium symporter activity
BT4G5_RS08625	COG1757	Na H antiporter
BT4G5_RS08640	COG4758	membrane
BT4G5_RS08645	COG4585	Histidine kinase
BT4G5_RS08650	COG2197	response regulator
BT4G5_RS08660	COG1114	Component of the transport system for branched-chain amino acids
BT4G5_RS08715	COG0730	response to heat
BT4G5_RS08720	COG0306	phosphate transporter
BT4G5_RS08725	COG1392	Phosphate transport regulator
BT4G5_RS08730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BT4G5_RS08745	COG3852	Histidine kinase
BT4G5_RS08750	COG1801	Protein of unknown function DUF72
BT4G5_RS08760	COG0582	viral genome integration into host DNA
BT4G5_RS08765	COG5002	protein histidine kinase activity
BT4G5_RS08780	COG0392	lysyltransferase activity
BT4G5_RS08780	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BT4G5_RS08795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BT4G5_RS08800	COG1686	Belongs to the peptidase S11 family
BT4G5_RS08805	COG2715	membrane protein required for spore maturation
BT4G5_RS08810	COG0700	Nucleoside recognition
BT4G5_RS08815	COG1187	pseudouridine synthase activity
BT4G5_RS08825	COG1333	cytochrome c biogenesis protein
BT4G5_RS08830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BT4G5_RS08835	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS08840	COG5002	protein histidine kinase activity
BT4G5_RS08845	COG2096	Adenosyltransferase
BT4G5_RS08860	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BT4G5_RS08865	COG1141	Ferredoxin
BT4G5_RS08875	COG0514	ATP-dependent DNA helicase (RecQ)
BT4G5_RS08880	COG1266	CAAX protease self-immunity
BT4G5_RS08890	COG1408	metallophosphoesterase
BT4G5_RS08895	COG0789	Transcriptional regulator
BT4G5_RS08905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BT4G5_RS08925	COG0492	ferredoxin-NADP+ reductase activity
BT4G5_RS08930	COG0252	asparaginase activity
BT4G5_RS09000	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BT4G5_RS09015	COG0142	geranyltranstransferase activity
BT4G5_RS09025	COG0142	geranyltranstransferase activity
BT4G5_RS09055	COG0457	Tetratricopeptide repeat
BT4G5_RS09075	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BT4G5_RS09080	COG2010	Cytochrome c
BT4G5_RS09080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BT4G5_RS09085	COG4347	Protein of unknown function (DUF1405)
BT4G5_RS09100	COG2738	Putative neutral zinc metallopeptidase
BT4G5_RS09110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT4G5_RS09115	COG1694	Mazg nucleotide pyrophosphohydrolase
BT4G5_RS09135	COG0438	transferase activity, transferring glycosyl groups
BT4G5_RS09175	COG1199	ATP-dependent helicase activity
BT4G5_RS09175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BT4G5_RS09195	COG3935	DnaD domain protein
BT4G5_RS09200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BT4G5_RS09210	COG4499	WXG100 protein secretion system (Wss), protein YukC
BT4G5_RS09210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BT4G5_RS09260	COG0116	Belongs to the methyltransferase superfamily
BT4G5_RS09270	COG1199	ATP-dependent helicase activity
BT4G5_RS09275	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BT4G5_RS09285	COG0024	Methionine aminopeptidase
BT4G5_RS09295	COG2233	PERMEase
BT4G5_RS09300	COG2311	Membrane
BT4G5_RS09305	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BT4G5_RS09315	COG0456	acetyltransferase
BT4G5_RS09335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BT4G5_RS09350	COG3944	biosynthesis protein
BT4G5_RS09360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BT4G5_RS09375	COG1215	transferase activity, transferring glycosyl groups
BT4G5_RS09380	COG0438	transferase activity, transferring glycosyl groups
BT4G5_RS09390	COG0454	-acetyltransferase
BT4G5_RS09410	COG0328	RNA-DNA hybrid ribonuclease activity
BT4G5_RS09445	COG3403	YqcI/YcgG family
BT4G5_RS09450	COG1280	lysine exporter protein (LysE YggA)
BT4G5_RS09470	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BT4G5_RS09475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BT4G5_RS09485	COG0475	glutathione-regulated potassium exporter activity
BT4G5_RS09490	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BT4G5_RS09495	COG4978	Transcriptional regulator
BT4G5_RS09495	COG0789	Transcriptional regulator
BT4G5_RS09505	COG2323	membrane
BT4G5_RS09510	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BT4G5_RS09550	COG1923	regulation of RNA biosynthetic process
BT4G5_RS09560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BT4G5_RS09565	COG1360	Flagellar Motor Protein
BT4G5_RS09570	COG2201	protein-glutamate methylesterase activity
BT4G5_RS09575	COG2198	Histidine kinase
BT4G5_RS09575	COG0643	Histidine kinase
BT4G5_RS09580	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BT4G5_RS09580	COG1776	CheC inhibitor of MCP methylation
BT4G5_RS09595	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BT4G5_RS09615	COG1256	bacterial-type flagellum assembly
BT4G5_RS09620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BT4G5_RS09640	COG1815	bacterial-type flagellum-dependent cell motility
BT4G5_RS09645	COG1558	bacterial-type flagellum-dependent cell motility
BT4G5_RS09655	COG1766	The M ring may be actively involved in energy transduction
BT4G5_RS09660	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BT4G5_RS09670	COG1157	protein secretion by the type III secretion system
BT4G5_RS09705	COG0835	chemotaxis
BT4G5_RS09705	COG0784	Response regulator, receiver
BT4G5_RS09720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BT4G5_RS09725	COG0741	lytic transglycosylase activity
BT4G5_RS09735	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BT4G5_RS09740	COG1776	CheC inhibitor of MCP methylation
BT4G5_RS09740	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BT4G5_RS09750	COG1338	Plays a role in the flagellum-specific transport system
BT4G5_RS09755	COG1987	bacterial-type flagellum assembly
BT4G5_RS09765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BT4G5_RS09770	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BT4G5_RS09775	COG1419	protein localization to endoplasmic reticulum
BT4G5_RS09780	COG4786	Flagellar basal body rod
BT4G5_RS09785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BT4G5_RS09820	COG2329	Antibiotic biosynthesis monooxygenase
BT4G5_RS09845	COG0583	DNA-binding transcription factor activity
BT4G5_RS09850	COG3842	ATPase activity
BT4G5_RS09885	COG1686	Belongs to the peptidase S11 family
BT4G5_RS09890	COG0406	alpha-ribazole phosphatase activity
BT4G5_RS09905	COG3547	Transposase (IS116 IS110 IS902 family)
BT4G5_RS09925	COG0367	asparagine synthase
BT4G5_RS09955	COG1802	Transcriptional regulator
BT4G5_RS09960	COG0697	spore germination
BT4G5_RS09970	COG0523	cobalamin synthesis protein
BT4G5_RS09975	COG0701	Predicted permease
BT4G5_RS09990	COG1757	Na H antiporter
BT4G5_RS09995	COG0789	Transcriptional regulator
BT4G5_RS10030	COG0534	Mate efflux family protein
BT4G5_RS10035	COG3340	Belongs to the peptidase S51 family
BT4G5_RS10055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BT4G5_RS10075	COG2733	membrane
BT4G5_RS10110	COG1131	(ABC) transporter
BT4G5_RS10130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BT4G5_RS10135	COG0528	UMP kinase activity
BT4G5_RS10145	COG1027	Aspartate ammonia-lyase
BT4G5_RS10150	COG0281	malic enzyme
BT4G5_RS10155	COG4191	Histidine kinase
BT4G5_RS10160	COG0784	Response regulator, receiver
BT4G5_RS10165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BT4G5_RS10190	COG3620	sequence-specific DNA binding
BT4G5_RS10250	COG1695	Transcriptional regulator
BT4G5_RS10260	COG0477	Major facilitator Superfamily
BT4G5_RS10270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BT4G5_RS10275	COG2223	nitrite transmembrane transporter activity
BT4G5_RS10280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BT4G5_RS10300	COG0733	neurotransmitter:sodium symporter activity
BT4G5_RS10305	COG5566	PFAM Mor transcription activator
BT4G5_RS10310	COG2323	membrane
BT4G5_RS10330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BT4G5_RS10340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BT4G5_RS10345	COG0028	Belongs to the TPP enzyme family
BT4G5_RS10365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BT4G5_RS10390	COG2814	Major facilitator Superfamily
BT4G5_RS10395	COG3384	dioxygenase
BT4G5_RS10415	COG3279	Response regulator of the LytR AlgR family
BT4G5_RS10420	COG0427	acetyl-CoA hydrolase
BT4G5_RS10440	COG4166	transmembrane transport
BT4G5_RS10445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS10450	COG1914	H( )-stimulated, divalent metal cation uptake system
BT4G5_RS10465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BT4G5_RS10475	COG0531	amino acid
BT4G5_RS10510	COG1309	transcriptional regulator
BT4G5_RS10515	COG2390	Transcriptional regulator
BT4G5_RS10525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT4G5_RS10530	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BT4G5_RS10545	COG4846	Membrane protein involved in cytochrome C biogenesis
BT4G5_RS10555	COG0006	proline dipeptidase activity
BT4G5_RS10565	COG2132	Multicopper oxidase
BT4G5_RS10575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BT4G5_RS10595	COG1114	Component of the transport system for branched-chain amino acids
BT4G5_RS10600	COG2801	Transposase and inactivated derivatives
BT4G5_RS10615	COG2372	response to copper ion
BT4G5_RS10615	COG1276	copper resistance
BT4G5_RS10620	COG4549	nuclear export factor GLE1
BT4G5_RS10625	COG0697	spore germination
BT4G5_RS10630	COG0583	DNA-binding transcription factor activity
BT4G5_RS10635	COG1959	2 iron, 2 sulfur cluster binding
BT4G5_RS10640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BT4G5_RS10645	COG0778	Nitroreductase
BT4G5_RS10660	COG0628	permease
BT4G5_RS10670	COG1231	oxidoreductase activity
BT4G5_RS10675	COG0523	cobalamin synthesis protein
BT4G5_RS10685	COG0411	ABC transporter
BT4G5_RS10705	COG0583	DNA-binding transcription factor activity
BT4G5_RS10725	COG1942	4-Oxalocrotonate Tautomerase
BT4G5_RS10745	COG1271	oxidase subunit
BT4G5_RS10750	COG1294	oxidase, subunit
BT4G5_RS10755	COG4988	ABC transporter
BT4G5_RS10760	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BT4G5_RS10770	COG1216	Glycosyl transferase, family 2
BT4G5_RS10810	COG1686	Belongs to the peptidase S11 family
BT4G5_RS10825	COG0791	NLP P60 protein
BT4G5_RS10825	COG1388	LysM domain
BT4G5_RS10835	COG1132	(ABC) transporter
BT4G5_RS10840	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS10845	COG5002	protein histidine kinase activity
BT4G5_RS10850	COG0300	oxidoreductase activity
BT4G5_RS10880	COG0460	homoserine dehydrogenase
BT4G5_RS10905	COG1316	TRANSCRIPTIONal
BT4G5_RS10915	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS10920	COG5002	protein histidine kinase activity
BT4G5_RS10935	COG1285	pathogenesis
BT4G5_RS10940	COG1247	-acetyltransferase
BT4G5_RS10970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BT4G5_RS10980	COG1082	Xylose isomerase domain protein TIM barrel
BT4G5_RS10990	COG2814	Major facilitator Superfamily
BT4G5_RS10995	COG1279	arginine transmembrane transporter activity
BT4G5_RS11000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT4G5_RS11010	COG1752	Esterase of the alpha-beta hydrolase superfamily
BT4G5_RS11045	COG0577	efflux transmembrane transporter activity
BT4G5_RS11050	COG2002	toxin-antitoxin pair type II binding
BT4G5_RS11055	COG1404	Belongs to the peptidase S8 family
BT4G5_RS11060	COG0640	Transcriptional regulator
BT4G5_RS11065	COG0667	Aldo Keto reductase
BT4G5_RS11070	COG2814	Major facilitator Superfamily
BT4G5_RS11080	COG3152	Membrane
BT4G5_RS11105	COG0840	transmembrane signaling receptor activity
BT4G5_RS11125	COG3949	Membrane
BT4G5_RS11130	COG0783	Belongs to the Dps family
BT4G5_RS11145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BT4G5_RS11155	COG1231	oxidoreductase activity
BT4G5_RS11160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS11165	COG4989	oxidoreductase activity
BT4G5_RS11175	COG0523	cobalamin synthesis protein
BT4G5_RS11180	COG0456	acetyltransferase
BT4G5_RS11185	COG0803	Belongs to the bacterial solute-binding protein 9 family
BT4G5_RS11195	COG0702	epimerase
BT4G5_RS11205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BT4G5_RS11215	COG4166	transmembrane transport
BT4G5_RS11240	COG5337	Spore coat protein CotH
BT4G5_RS11245	COG1051	belongs to the nudix hydrolase family
BT4G5_RS11250	COG0586	Pfam SNARE associated Golgi protein
BT4G5_RS11265	COG0701	Predicted permease
BT4G5_RS11270	COG3689	TIGRFAM TIGR03943 family protein
BT4G5_RS11275	COG1607	acyl-coa hydrolase
BT4G5_RS11280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BT4G5_RS11295	COG0702	epimerase
BT4G5_RS11300	COG2839	Protein conserved in bacteria
BT4G5_RS11305	COG1253	flavin adenine dinucleotide binding
BT4G5_RS11320	COG2963	transposase activity
BT4G5_RS11325	COG2801	Transposase and inactivated derivatives
BT4G5_RS11330	COG2801	Transposase and inactivated derivatives
BT4G5_RS11335	COG2963	transposase activity
BT4G5_RS11340	COG2963	transposase activity
BT4G5_RS11345	COG2801	Transposase and inactivated derivatives
BT4G5_RS11350	COG1114	Component of the transport system for branched-chain amino acids
BT4G5_RS11355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BT4G5_RS11375	COG0860	N-Acetylmuramoyl-L-alanine amidase
BT4G5_RS11385	COG1876	peptidase activity
BT4G5_RS11400	COG2211	Major facilitator Superfamily
BT4G5_RS11415	COG0860	N-Acetylmuramoyl-L-alanine amidase
BT4G5_RS11425	COG0561	phosphatase activity
BT4G5_RS11440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BT4G5_RS11450	COG1819	glycosyl
BT4G5_RS11455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT4G5_RS11460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT4G5_RS11490	COG0456	acetyltransferase
BT4G5_RS11525	COG4499	WXG100 protein secretion system (Wss), protein YukC
BT4G5_RS11590	COG3874	Sporulation protein YtfJ
BT4G5_RS11615	COG2226	methyltransferase
BT4G5_RS11635	COG2801	Transposase and inactivated derivatives
BT4G5_RS11645	COG1082	Xylose isomerase domain protein TIM barrel
BT4G5_RS11650	COG0346	lactoylglutathione lyase activity
BT4G5_RS11665	COG1595	DNA-templated transcription, initiation
BT4G5_RS11680	COG0426	domain, Protein
BT4G5_RS11680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BT4G5_RS11690	COG0386	Belongs to the glutathione peroxidase family
BT4G5_RS11700	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BT4G5_RS11705	COG0714	Associated with various cellular activities
BT4G5_RS11710	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BT4G5_RS11715	COG1140	nitrate reductase beta subunit
BT4G5_RS11720	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BT4G5_RS11725	COG2181	nitrate reductase activity
BT4G5_RS11730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BT4G5_RS11735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BT4G5_RS11740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BT4G5_RS11745	COG0303	'Molybdopterin
BT4G5_RS11750	COG0314	molybdopterin synthase activity
BT4G5_RS11755	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BT4G5_RS11760	COG2223	nitrite transmembrane transporter activity
BT4G5_RS11770	COG1648	precorrin-2 dehydrogenase activity
BT4G5_RS11780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BT4G5_RS11780	COG1587	Uroporphyrinogen-III synthase
BT4G5_RS11785	COG2146	nitrite reductase [NAD(P)H] activity
BT4G5_RS11790	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BT4G5_RS11795	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BT4G5_RS11830	COG2359	stage V sporulation protein S
BT4G5_RS11855	COG0730	response to heat
BT4G5_RS11880	COG0457	Tetratricopeptide repeat
BT4G5_RS11895	COG1418	mRNA catabolic process
BT4G5_RS11900	COG0488	(ABC) transporter
BT4G5_RS11945	COG1476	TRANSCRIPTIONal
BT4G5_RS11965	COG0629	single-stranded DNA binding
BT4G5_RS11975	COG1413	lyase activity
BT4G5_RS11990	COG2521	methyltransferase
BT4G5_RS11990	COG2136	Putative SAM-dependent methyltransferase
BT4G5_RS11995	COG0018	arginyl-trna synthetase
BT4G5_RS12040	COG2801	Transposase and inactivated derivatives
BT4G5_RS12045	COG2963	transposase activity
BT4G5_RS12055	COG0017	Asparaginyl-tRNA synthetase
BT4G5_RS12085	COG2610	gluconate transmembrane transporter activity
BT4G5_RS12095	COG1794	racemase activity, acting on amino acids and derivatives
BT4G5_RS12105	COG0456	acetyltransferase
BT4G5_RS12115	COG3655	Transcriptional regulator
BT4G5_RS12120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BT4G5_RS12130	COG1131	(ABC) transporter
BT4G5_RS12135	COG4473	ABC transporter
BT4G5_RS12145	COG0546	phosphoglycolate phosphatase activity
BT4G5_RS12160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BT4G5_RS12175	COG0768	penicillin binding
BT4G5_RS12185	COG0204	Acyl-transferase
BT4G5_RS12195	COG2801	Transposase and inactivated derivatives
BT4G5_RS12200	COG1272	protein, Hemolysin III
BT4G5_RS12210	COG0805	protein transport
BT4G5_RS12220	COG1307	EDD domain protein, DegV family
BT4G5_RS12230	COG1999	signal sequence binding
BT4G5_RS12235	COG0071	Belongs to the small heat shock protein (HSP20) family
BT4G5_RS12240	COG0367	asparagine synthase
BT4G5_RS12255	COG0860	N-Acetylmuramoyl-L-alanine amidase
BT4G5_RS12260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT4G5_RS12265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BT4G5_RS12285	COG1335	isochorismatase
BT4G5_RS12295	COG0668	transmembrane transport
BT4G5_RS12300	COG4585	Histidine kinase
BT4G5_RS12300	COG2203	Gaf domain
BT4G5_RS12305	COG2197	response regulator
BT4G5_RS12310	COG1737	Transcriptional regulator
BT4G5_RS12315	COG0384	phenazine biosynthesis protein PhzF
BT4G5_RS12320	COG1064	alcohol dehydrogenase
BT4G5_RS12345	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BT4G5_RS12380	COG0517	IMP dehydrogenase activity
BT4G5_RS12380	COG1125	glycine betaine transport
BT4G5_RS12385	COG1174	glycine betaine transport
BT4G5_RS12420	COG1253	flavin adenine dinucleotide binding
BT4G5_RS12425	COG1012	belongs to the aldehyde dehydrogenase family
BT4G5_RS12430	COG5506	Protein of unknown function (DUF1694)
BT4G5_RS12445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BT4G5_RS12450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BT4G5_RS12455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BT4G5_RS12460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BT4G5_RS12465	COG0456	acetyltransferase
BT4G5_RS12470	COG3829	transcription factor binding
BT4G5_RS12475	COG1509	lysine 2,3-aminomutase activity
BT4G5_RS12510	COG4991	sh3 domain protein
BT4G5_RS12510	COG0515	serine threonine protein kinase
BT4G5_RS12510	COG3064	Membrane
BT4G5_RS12520	COG0671	phosphoesterase, PA-phosphatase related
BT4G5_RS12525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BT4G5_RS12530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BT4G5_RS12575	COG2801	Transposase and inactivated derivatives
BT4G5_RS12610	COG0300	oxidoreductase activity
BT4G5_RS12630	COG4499	WXG100 protein secretion system (Wss), protein YukC
BT4G5_RS12630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BT4G5_RS12640	COG2814	Major facilitator Superfamily
BT4G5_RS12645	COG4841	protein insertion into membrane
BT4G5_RS12650	COG0372	Belongs to the citrate synthase family
BT4G5_RS12655	COG2079	MmgE PrpD family protein
BT4G5_RS12660	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BT4G5_RS12665	COG1960	acyl-CoA dehydrogenase activity
BT4G5_RS12670	COG2084	Dehydrogenase
BT4G5_RS12680	COG1280	lysine exporter protein (LysE YggA)
BT4G5_RS12685	COG1024	Enoyl-CoA hydratase
BT4G5_RS12700	COG0420	3'-5' exonuclease activity
BT4G5_RS12705	COG0419	ATPase involved in DNA repair
BT4G5_RS12730	COG2223	nitrite transmembrane transporter activity
BT4G5_RS12735	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS12740	COG1169	isochorismate synthase
BT4G5_RS12745	COG1021	2,3-dihydroxybenzoate-AMP ligase
BT4G5_RS12750	COG1535	isochorismatase
BT4G5_RS12750	COG3433	isochorismatase activity
BT4G5_RS12755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BT4G5_RS12760	COG3251	PFAM MbtH domain protein
BT4G5_RS12765	COG2814	Major facilitator Superfamily
BT4G5_RS12780	COG0776	regulation of translation
BT4G5_RS12790	COG2318	DinB family
BT4G5_RS12800	COG1115	amino acid carrier protein
BT4G5_RS12815	COG2329	Antibiotic biosynthesis monooxygenase
BT4G5_RS12820	COG1187	pseudouridine synthase activity
BT4G5_RS12825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BT4G5_RS12830	COG1136	(ABC) transporter
BT4G5_RS12840	COG0028	Belongs to the TPP enzyme family
BT4G5_RS12880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BT4G5_RS12905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT4G5_RS12940	COG1247	-acetyltransferase
BT4G5_RS12965	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BT4G5_RS12975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS13010	COG0583	DNA-binding transcription factor activity
BT4G5_RS13015	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BT4G5_RS13035	COG0583	DNA-binding transcription factor activity
BT4G5_RS13040	COG2258	MOSC domain
BT4G5_RS13055	COG1132	(ABC) transporter
BT4G5_RS13060	COG1132	(ABC) transporter
BT4G5_RS13085	COG1396	sequence-specific DNA binding
BT4G5_RS13150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BT4G5_RS13155	COG1595	DNA-templated transcription, initiation
BT4G5_RS13180	COG1649	PFAM Uncharacterised BCR, COG1649
BT4G5_RS13200	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BT4G5_RS13205	COG2971	BadF BadG BcrA BcrD
BT4G5_RS13225	COG1846	Transcriptional regulator
BT4G5_RS13245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT4G5_RS13265	COG1309	transcriptional regulator
BT4G5_RS13290	COG3615	Tellurite resistance protein tehB
BT4G5_RS13290	COG0500	methyltransferase
BT4G5_RS13300	COG2226	methyltransferase
BT4G5_RS13305	COG3961	Belongs to the TPP enzyme family
BT4G5_RS13310	COG1846	Transcriptional regulator
BT4G5_RS13340	COG2195	Cleaves the N-terminal amino acid of tripeptides
BT4G5_RS13365	COG2002	toxin-antitoxin pair type II binding
BT4G5_RS13375	COG0730	response to heat
BT4G5_RS13380	COG0110	maltose O-acetyltransferase activity
BT4G5_RS13385	COG1686	Belongs to the peptidase S11 family
BT4G5_RS13395	COG2814	Major facilitator Superfamily
BT4G5_RS13425	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS13455	COG0741	lytic transglycosylase activity
BT4G5_RS13460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS13465	COG2239	Acts as a magnesium transporter
BT4G5_RS13560	COG1396	sequence-specific DNA binding
BT4G5_RS13580	COG1309	transcriptional regulator
BT4G5_RS13585	COG0367	asparagine synthase
BT4G5_RS13615	COG1760	l-serine dehydratase
BT4G5_RS13620	COG1760	l-serine dehydratase
BT4G5_RS13625	COG0814	amino acid
BT4G5_RS13645	COG1533	DNA photolyase activity
BT4G5_RS13655	COG0076	glutamate decarboxylase activity
BT4G5_RS13680	COG0772	Belongs to the SEDS family
BT4G5_RS13685	COG2239	Acts as a magnesium transporter
BT4G5_RS13695	COG0768	penicillin binding
BT4G5_RS13700	COG1595	DNA-templated transcription, initiation
BT4G5_RS13710	COG0768	penicillin binding
BT4G5_RS13715	COG0768	penicillin binding
BT4G5_RS13730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT4G5_RS13745	COG1131	(ABC) transporter
BT4G5_RS13755	COG1309	transcriptional regulator
BT4G5_RS13770	COG1960	acyl-CoA dehydrogenase activity
BT4G5_RS13775	COG0439	Biotin carboxylase
BT4G5_RS13780	COG0511	ligase activity, forming carbon-carbon bonds
BT4G5_RS13785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BT4G5_RS13790	COG1024	Enoyl-CoA hydratase
BT4G5_RS13795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BT4G5_RS13800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BT4G5_RS13835	COG0572	uridine kinase
BT4G5_RS13850	COG1686	Belongs to the peptidase S11 family
BT4G5_RS13875	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BT4G5_RS13890	COG3227	Zinc metalloprotease (Elastase)
BT4G5_RS13895	COG2207	Transcriptional regulator
BT4G5_RS13940	COG1942	4-Oxalocrotonate Tautomerase
BT4G5_RS13945	COG0583	DNA-binding transcription factor activity
BT4G5_RS13955	COG1131	(ABC) transporter
BT4G5_RS13985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT4G5_RS13990	COG2368	4-hydroxyphenylacetate
BT4G5_RS14015	COG2323	membrane
BT4G5_RS14020	COG0693	protein deglycase activity
BT4G5_RS14030	COG3386	PFAM SMP-30 Gluconolaconase
BT4G5_RS14040	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BT4G5_RS14045	COG3773	Cell wall hydrolase
BT4G5_RS14055	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS14060	COG2205	protein histidine kinase activity
BT4G5_RS14065	COG0488	(ABC) transporter
BT4G5_RS14075	COG1136	(ABC) transporter
BT4G5_RS14080	COG0577	efflux transmembrane transporter activity
BT4G5_RS14100	COG0460	homoserine dehydrogenase
BT4G5_RS14105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT4G5_RS14115	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BT4G5_RS14180	COG2124	cytochrome p450
BT4G5_RS14215	COG0561	phosphatase activity
BT4G5_RS14220	COG5002	protein histidine kinase activity
BT4G5_RS14225	COG0768	penicillin binding
BT4G5_RS14235	COG1819	glycosyl
BT4G5_RS14240	COG1794	racemase activity, acting on amino acids and derivatives
BT4G5_RS14260	COG2205	protein histidine kinase activity
BT4G5_RS14265	COG0582	viral genome integration into host DNA
BT4G5_RS14305	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BT4G5_RS14320	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BT4G5_RS14330	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS14335	COG5002	protein histidine kinase activity
BT4G5_RS14340	COG0604	alcohol dehydrogenase
BT4G5_RS14345	COG0671	phosphoesterase, PA-phosphatase related
BT4G5_RS14350	COG0768	penicillin binding
BT4G5_RS14405	COG2814	Major facilitator Superfamily
BT4G5_RS14410	COG2814	Major facilitator Superfamily
BT4G5_RS14425	COG0584	glycerophosphoryl diester phosphodiesterase
BT4G5_RS14440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT4G5_RS14445	COG0697	spore germination
BT4G5_RS14480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BT4G5_RS14490	COG2223	nitrite transmembrane transporter activity
BT4G5_RS14505	COG0592	DNA-directed DNA polymerase activity
BT4G5_RS14530	COG3878	Protein conserved in bacteria
BT4G5_RS14550	COG4667	esterase of the alpha-beta hydrolase superfamily
BT4G5_RS14585	COG0322	excinuclease ABC activity
BT4G5_RS14605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BT4G5_RS14630	COG1011	Hydrolase
BT4G5_RS14635	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS14640	COG5002	protein histidine kinase activity
BT4G5_RS14655	COG1136	(ABC) transporter
BT4G5_RS14660	COG0577	efflux transmembrane transporter activity
BT4G5_RS14665	COG1073	alpha beta
BT4G5_RS14670	COG0657	acetylesterase activity
BT4G5_RS14675	COG0076	glutamate decarboxylase activity
BT4G5_RS14690	COG1523	belongs to the glycosyl hydrolase 13 family
BT4G5_RS14695	COG3227	Zinc metalloprotease (Elastase)
BT4G5_RS14700	COG0737	Belongs to the 5'-nucleotidase family
BT4G5_RS14715	COG0201	protein transport
BT4G5_RS14720	COG0697	spore germination
BT4G5_RS14725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT4G5_RS14765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS14780	COG2959	enzyme of heme biosynthesis
BT4G5_RS14820	COG1309	transcriptional regulator
BT4G5_RS14850	COG3284	Transcriptional regulator
BT4G5_RS14885	COG1959	2 iron, 2 sulfur cluster binding
BT4G5_RS14895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BT4G5_RS14900	COG0508	dehydrogenase complex catalyzes the overall conversion of
BT4G5_RS14905	COG0022	dehydrogenase e1 component
BT4G5_RS14910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BT4G5_RS14920	COG2814	Major facilitator Superfamily
BT4G5_RS14930	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS14935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BT4G5_RS14935	COG0456	acetyltransferase
BT4G5_RS14975	COG4176	ABC-type proline glycine betaine transport system permease component
BT4G5_RS14980	COG0517	IMP dehydrogenase activity
BT4G5_RS14980	COG4175	Glycine betaine
BT4G5_RS15010	COG2153	protein acetylation
BT4G5_RS15015	COG3397	chitin binding
BT4G5_RS15020	COG1819	glycosyl
BT4G5_RS15040	COG2205	protein histidine kinase activity
BT4G5_RS15045	COG2226	methyltransferase
BT4G5_RS15050	COG2315	Protein conserved in bacteria
BT4G5_RS15095	COG0456	acetyltransferase
BT4G5_RS15100	COG3973	AAA domain
BT4G5_RS15110	COG2105	PFAM AIG2 family protein
BT4G5_RS15115	COG0514	ATP-dependent DNA helicase (RecQ)
BT4G5_RS15145	COG2801	Transposase and inactivated derivatives
BT4G5_RS15160	COG4637	Psort location Cytoplasmic, score
BT4G5_RS15175	COG3397	chitin binding
BT4G5_RS15190	COG1162	GTPase activity
BT4G5_RS15195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BT4G5_RS15200	COG1115	amino acid carrier protein
BT4G5_RS15205	COG1012	belongs to the aldehyde dehydrogenase family
BT4G5_RS15210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BT4G5_RS15220	COG3938	Belongs to the proline racemase family
BT4G5_RS15225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BT4G5_RS15265	COG0586	Pfam SNARE associated Golgi protein
BT4G5_RS15275	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BT4G5_RS15285	COG4166	transmembrane transport
BT4G5_RS15295	COG4948	Mandelate Racemase Muconate Lactonizing
BT4G5_RS15310	COG0667	Aldo Keto reductase
BT4G5_RS15355	COG5002	protein histidine kinase activity
BT4G5_RS15355	COG3850	Histidine kinase
BT4G5_RS15360	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS15380	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BT4G5_RS15390	COG1164	Oligoendopeptidase f
BT4G5_RS15395	COG1307	EDD domain protein, DegV family
BT4G5_RS15400	COG2801	Transposase and inactivated derivatives
BT4G5_RS15405	COG2963	transposase activity
BT4G5_RS15445	COG2814	Major facilitator Superfamily
BT4G5_RS15455	COG1664	Polymer-forming cytoskeletal
BT4G5_RS15460	COG0789	Transcriptional regulator
BT4G5_RS15465	COG4533	DNA binding
BT4G5_RS15470	COG0477	Major facilitator Superfamily
BT4G5_RS15470	COG2814	Major facilitator Superfamily
BT4G5_RS15490	COG2261	transglycosylase associated protein
BT4G5_RS15505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BT4G5_RS15540	COG0436	Aminotransferase
BT4G5_RS15545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BT4G5_RS15555	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BT4G5_RS15570	COG1131	(ABC) transporter
BT4G5_RS15625	COG0628	permease
BT4G5_RS15640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BT4G5_RS15645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BT4G5_RS15650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BT4G5_RS15680	COG2746	aminoglycoside 3-N-acetyltransferase activity
BT4G5_RS15700	COG0697	spore germination
BT4G5_RS15720	COG4912	Dna alkylation repair
BT4G5_RS15725	COG0346	lactoylglutathione lyase activity
BT4G5_RS15735	COG0861	Integral membrane protein TerC family
BT4G5_RS15740	COG1368	sulfuric ester hydrolase activity
BT4G5_RS15745	COG0488	(ABC) transporter
BT4G5_RS15750	COG1033	growth of symbiont in host cell
BT4G5_RS15750	COG2409	Drug exporters of the RND superfamily
BT4G5_RS15755	COG1309	transcriptional regulator
BT4G5_RS15770	COG0287	Prephenate dehydrogenase
BT4G5_RS15785	COG1605	Chorismate mutase
BT4G5_RS15785	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BT4G5_RS15825	COG1388	LysM domain
BT4G5_RS15825	COG3584	3D domain protein
BT4G5_RS15835	COG0277	FAD linked oxidase domain protein
BT4G5_RS15855	COG1879	ABC-type sugar transport system periplasmic component
BT4G5_RS15865	COG1172	Belongs to the binding-protein-dependent transport system permease family
BT4G5_RS15875	COG2390	Transcriptional regulator
BT4G5_RS15880	COG1070	Carbohydrate kinase
BT4G5_RS15905	COG2329	Antibiotic biosynthesis monooxygenase
BT4G5_RS15925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT4G5_RS15935	COG2801	Transposase and inactivated derivatives
BT4G5_RS15950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BT4G5_RS15955	COG4187	Peptidase family M20/M25/M40
BT4G5_RS15960	COG1414	Transcriptional regulator
BT4G5_RS15965	COG0833	amino acid
BT4G5_RS15975	COG3239	Fatty acid desaturase
BT4G5_RS15985	COG2720	vancomycin resistance protein
BT4G5_RS15990	COG1785	Belongs to the alkaline phosphatase family
BT4G5_RS16000	COG3655	Transcriptional regulator
BT4G5_RS16020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS16025	COG0346	lactoylglutathione lyase activity
BT4G5_RS16045	COG0714	Associated with various cellular activities
BT4G5_RS16090	COG0463	Glycosyl transferase, family 2
BT4G5_RS16115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BT4G5_RS16120	COG0753	catalase activity
BT4G5_RS16160	COG0714	Associated with various cellular activities
BT4G5_RS16220	COG0778	Nitroreductase
BT4G5_RS16225	COG1846	Transcriptional regulator
BT4G5_RS16245	COG3831	ATPase activity
BT4G5_RS16245	COG4884	unkown
BT4G5_RS16270	COG0590	tRNA wobble adenosine to inosine editing
BT4G5_RS16270	COG0037	tRNA processing
BT4G5_RS16275	COG0456	acetyltransferase
BT4G5_RS16290	COG0697	spore germination
BT4G5_RS16295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT4G5_RS16335	COG0730	response to heat
BT4G5_RS16345	COG0833	amino acid
BT4G5_RS16390	COG0768	penicillin binding
BT4G5_RS16425	COG1984	allophanate hydrolase subunit 2
BT4G5_RS16430	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BT4G5_RS16435	COG1414	Transcriptional regulator
BT4G5_RS16445	COG3142	Participates in the control of copper homeostasis
BT4G5_RS16450	COG0640	Transcriptional regulator
BT4G5_RS16460	COG1960	acyl-CoA dehydrogenase activity
BT4G5_RS16475	COG3314	Sporulation integral membrane protein YlbJ
BT4G5_RS16485	COG0454	-acetyltransferase
BT4G5_RS16495	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BT4G5_RS16505	COG2801	Transposase and inactivated derivatives
BT4G5_RS16510	COG2963	transposase activity
BT4G5_RS16525	COG0574	Belongs to the PEP-utilizing enzyme family
BT4G5_RS16525	COG3848	Pyruvate phosphate dikinase
BT4G5_RS16540	COG1522	sequence-specific DNA binding
BT4G5_RS16545	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS16550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT4G5_RS16570	COG1063	alcohol dehydrogenase
BT4G5_RS16575	COG5002	protein histidine kinase activity
BT4G5_RS16600	COG2207	Transcriptional regulator
BT4G5_RS16620	COG0737	Belongs to the 5'-nucleotidase family
BT4G5_RS16625	COG2267	carboxylic ester hydrolase activity
BT4G5_RS16630	COG1335	isochorismatase
BT4G5_RS16650	COG0583	DNA-binding transcription factor activity
BT4G5_RS16685	COG0598	Magnesium transport protein CorA
BT4G5_RS16755	COG0657	acetylesterase activity
BT4G5_RS16760	COG0288	reversible hydration of carbon dioxide
BT4G5_RS16770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BT4G5_RS16775	COG5609	conserved protein (DUF2294)
BT4G5_RS16785	COG0456	acetyltransferase
BT4G5_RS16790	COG1575	Belongs to the MenA family. Type 1 subfamily
BT4G5_RS16800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS16810	COG0798	PFAM Bile acid sodium symporter
BT4G5_RS16815	COG0346	lactoylglutathione lyase activity
BT4G5_RS16820	COG0640	Transcriptional regulator
BT4G5_RS16830	COG2814	Major facilitator Superfamily
BT4G5_RS16835	COG1309	transcriptional regulator
BT4G5_RS16840	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS16845	COG1522	sequence-specific DNA binding
BT4G5_RS16855	COG2963	transposase activity
BT4G5_RS16860	COG2801	Transposase and inactivated derivatives
BT4G5_RS16870	COG0346	lactoylglutathione lyase activity
BT4G5_RS16945	COG2814	Major facilitator Superfamily
BT4G5_RS16965	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BT4G5_RS16975	COG1690	Belongs to the RtcB family
BT4G5_RS16985	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BT4G5_RS17005	COG0577	efflux transmembrane transporter activity
BT4G5_RS17010	COG3850	Histidine kinase
BT4G5_RS17010	COG5002	protein histidine kinase activity
BT4G5_RS17020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT4G5_RS17050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BT4G5_RS17080	COG3831	ATPase activity
BT4G5_RS17090	COG5632	N-Acetylmuramoyl-L-alanine amidase
BT4G5_RS17090	COG3409	Peptidoglycan-binding domain 1 protein
BT4G5_RS17175	COG5444	nuclease activity
BT4G5_RS17200	COG1876	peptidase activity
BT4G5_RS17205	COG2843	Capsule synthesis protein
BT4G5_RS17215	COG0477	Major facilitator Superfamily
BT4G5_RS17230	COG1846	Transcriptional regulator
BT4G5_RS17235	COG2814	Major facilitator Superfamily
BT4G5_RS17250	COG2031	fatty acid transporter
BT4G5_RS17260	COG2249	NAD(P)H dehydrogenase (quinone) activity
BT4G5_RS17315	COG1288	antiporter activity
BT4G5_RS17330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BT4G5_RS17340	COG1733	regulation of RNA biosynthetic process
BT4G5_RS17345	COG0778	Nitroreductase
BT4G5_RS17355	COG0469	pyruvate kinase activity
BT4G5_RS17375	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS17385	COG1131	(ABC) transporter
BT4G5_RS17410	COG1011	Hydrolase
BT4G5_RS17420	COG2365	Tyrosine phosphatase family
BT4G5_RS17455	COG0628	permease
BT4G5_RS17480	COG0500	methyltransferase
BT4G5_RS17490	COG0477	Major facilitator Superfamily
BT4G5_RS17520	COG1253	flavin adenine dinucleotide binding
BT4G5_RS17525	COG0789	Transcriptional regulator
BT4G5_RS17535	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BT4G5_RS17565	COG0697	spore germination
BT4G5_RS17575	COG1357	PFAM Pentapeptide repeats (8 copies)
BT4G5_RS17580	COG3813	Protein conserved in bacteria
BT4G5_RS17585	COG2706	6-phosphogluconolactonase activity
BT4G5_RS17590	COG1070	Carbohydrate kinase
BT4G5_RS17600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BT4G5_RS17605	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BT4G5_RS17610	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BT4G5_RS17615	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BT4G5_RS17645	COG0840	transmembrane signaling receptor activity
BT4G5_RS17655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BT4G5_RS17655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BT4G5_RS17660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BT4G5_RS17660	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BT4G5_RS17665	COG1733	regulation of RNA biosynthetic process
BT4G5_RS17680	COG0814	amino acid
BT4G5_RS17705	COG2188	Transcriptional regulator
BT4G5_RS17710	COG0673	inositol 2-dehydrogenase activity
BT4G5_RS17730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT4G5_RS17750	COG0384	phenazine biosynthesis protein PhzF
BT4G5_RS17770	COG0318	PFAM AMP-dependent synthetase and ligase
BT4G5_RS17775	COG2249	NAD(P)H dehydrogenase (quinone) activity
BT4G5_RS17780	COG1733	regulation of RNA biosynthetic process
BT4G5_RS17805	COG1191	sigma factor activity
BT4G5_RS17860	COG1151	hydroxylamine reductase activity
BT4G5_RS17915	COG1113	amino acid transport
BT4G5_RS17920	COG2814	Major facilitator Superfamily
BT4G5_RS17955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BT4G5_RS17960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BT4G5_RS17970	COG1247	-acetyltransferase
BT4G5_RS17975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT4G5_RS17980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT4G5_RS17985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT4G5_RS17990	COG3739	integral membrane protein
BT4G5_RS18000	COG2801	Transposase and inactivated derivatives
BT4G5_RS18020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS18035	COG0583	DNA-binding transcription factor activity
BT4G5_RS18045	COG2890	protein-(glutamine-N5) methyltransferase activity
BT4G5_RS18060	COG1193	negative regulation of DNA recombination
BT4G5_RS18070	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BT4G5_RS18075	COG1164	Oligoendopeptidase f
BT4G5_RS18105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BT4G5_RS18135	COG2801	Transposase and inactivated derivatives
BT4G5_RS18140	COG0584	glycerophosphoryl diester phosphodiesterase
BT4G5_RS18155	COG0640	Transcriptional regulator
BT4G5_RS18160	COG0604	alcohol dehydrogenase
BT4G5_RS18175	COG0457	Tetratricopeptide repeat
BT4G5_RS18185	COG0385	Bile acid
BT4G5_RS18190	COG0277	FAD linked oxidase domain protein
BT4G5_RS18215	COG1183	phosphatidylcholine synthase activity
BT4G5_RS18225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BT4G5_RS18225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT4G5_RS18230	COG1252	NADH dehydrogenase
BT4G5_RS18240	COG0823	Involved in the tonB-independent uptake of proteins
BT4G5_RS18245	COG3397	chitin binding
BT4G5_RS18255	COG0697	spore germination
BT4G5_RS18285	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BT4G5_RS18295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BT4G5_RS18305	COG0457	Tetratricopeptide repeat
BT4G5_RS18340	COG1404	Belongs to the peptidase S8 family
BT4G5_RS18375	COG0488	(ABC) transporter
BT4G5_RS18400	COG3852	Histidine kinase
BT4G5_RS18410	COG1285	pathogenesis
BT4G5_RS18420	COG2514	catechol 2,3-dioxygenase activity
BT4G5_RS18425	COG2720	vancomycin resistance protein
BT4G5_RS18465	COG0716	FMN binding
BT4G5_RS18500	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS18510	COG0165	Argininosuccinate lyase
BT4G5_RS18525	COG4145	pantothenate transmembrane transporter activity
BT4G5_RS18535	COG1012	belongs to the aldehyde dehydrogenase family
BT4G5_RS18540	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS18550	COG1657	PFAM Prenyltransferase squalene oxidase
BT4G5_RS18555	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BT4G5_RS18560	COG2962	Rard protein
BT4G5_RS18565	COG3326	Membrane
BT4G5_RS18580	COG0489	protein tyrosine kinase activity
BT4G5_RS18590	COG0314	molybdopterin synthase activity
BT4G5_RS18595	COG0303	'Molybdopterin
BT4G5_RS18600	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BT4G5_RS18605	COG2116	formate transmembrane transporter activity
BT4G5_RS18615	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BT4G5_RS18620	COG5609	conserved protein (DUF2294)
BT4G5_RS18625	COG2427	Protein of unknown function (DUF1641)
BT4G5_RS18630	COG3383	formate dehydrogenase (NAD+) activity
BT4G5_RS18640	COG0697	spore germination
BT4G5_RS18655	COG0531	amino acid
BT4G5_RS18690	COG2226	methyltransferase
BT4G5_RS18695	COG4166	transmembrane transport
BT4G5_RS18700	COG4166	transmembrane transport
BT4G5_RS18705	COG4166	transmembrane transport
BT4G5_RS18710	COG1316	TRANSCRIPTIONal
BT4G5_RS18720	COG1595	DNA-templated transcription, initiation
BT4G5_RS18730	COG1131	(ABC) transporter
BT4G5_RS18750	COG0673	inositol 2-dehydrogenase activity
BT4G5_RS18755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BT4G5_RS18760	COG0187	DNA topoisomerase II activity
BT4G5_RS18770	COG1832	CoA-binding protein
BT4G5_RS18775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BT4G5_RS18780	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS18790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BT4G5_RS18790	COG1328	CTP reductase activity
BT4G5_RS18800	COG4841	protein insertion into membrane
BT4G5_RS18805	COG0824	Thioesterase
BT4G5_RS18840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BT4G5_RS18855	COG1132	(ABC) transporter
BT4G5_RS18870	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BT4G5_RS18900	COG2211	Major facilitator Superfamily
BT4G5_RS18910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BT4G5_RS18930	COG0318	PFAM AMP-dependent synthetase and ligase
BT4G5_RS18935	COG1268	BioY protein
BT4G5_RS18940	COG0318	PFAM AMP-dependent synthetase and ligase
BT4G5_RS18945	COG1396	sequence-specific DNA binding
BT4G5_RS18970	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BT4G5_RS18990	COG0830	nickel cation binding
BT4G5_RS19030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT4G5_RS19040	COG5002	protein histidine kinase activity
BT4G5_RS19045	COG0400	carboxylic ester hydrolase activity
BT4G5_RS19050	COG0346	lactoylglutathione lyase activity
BT4G5_RS19060	COG0069	glutamate synthase activity
BT4G5_RS19065	COG1902	pentaerythritol trinitrate reductase activity
BT4G5_RS19070	COG1329	Transcriptional regulator
BT4G5_RS19075	COG0010	Belongs to the arginase family
BT4G5_RS19100	COG2226	methyltransferase
BT4G5_RS19130	COG4846	Membrane protein involved in cytochrome C biogenesis
BT4G5_RS19135	COG0785	Cytochrome C biogenesis protein
BT4G5_RS19145	COG1473	amidohydrolase
BT4G5_RS19150	COG2963	transposase activity
BT4G5_RS19155	COG2801	Transposase and inactivated derivatives
BT4G5_RS19165	COG1131	(ABC) transporter
BT4G5_RS19180	COG0583	DNA-binding transcription factor activity
BT4G5_RS19190	COG1346	cytolysis
BT4G5_RS19205	COG0730	response to heat
BT4G5_RS19230	COG1132	(ABC) transporter
BT4G5_RS19235	COG1132	(ABC) transporter
BT4G5_RS19270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BT4G5_RS19275	COG0737	Belongs to the 5'-nucleotidase family
BT4G5_RS19285	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BT4G5_RS19305	COG1695	Transcriptional regulator
BT4G5_RS19310	COG0174	glutamine synthetase
BT4G5_RS19315	COG0789	Transcriptional regulator
BT4G5_RS19320	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BT4G5_RS19325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BT4G5_RS19330	COG2860	membrane
BT4G5_RS19335	COG0464	growth
BT4G5_RS19365	COG1388	LysM domain
BT4G5_RS19365	COG3584	3D domain protein
BT4G5_RS19370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BT4G5_RS19370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BT4G5_RS19370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BT4G5_RS19375	COG1105	Belongs to the carbohydrate kinase PfkB family
BT4G5_RS19380	COG1349	DNA-binding transcription factor activity
BT4G5_RS19385	COG1979	alcohol dehydrogenase
BT4G5_RS19390	COG2322	membrane
BT4G5_RS19405	COG1113	amino acid transport
BT4G5_RS19420	COG2116	formate transmembrane transporter activity
BT4G5_RS19435	COG2217	Heavy metal translocating P-type atpase
BT4G5_RS19440	COG2608	mercury ion transmembrane transporter activity
BT4G5_RS19445	COG1937	Protein conserved in bacteria
BT4G5_RS19455	COG2819	hydrolase of the alpha beta superfamily
BT4G5_RS19460	COG1120	ATPase activity
BT4G5_RS19465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT4G5_RS19470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT4G5_RS19475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT4G5_RS19480	COG2169	Transcriptional regulator
BT4G5_RS19485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BT4G5_RS19490	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BT4G5_RS19510	COG2267	carboxylic ester hydrolase activity
BT4G5_RS19515	COG5001	Diguanylate cyclase
BT4G5_RS19515	COG3300	MHYT domain
BT4G5_RS19535	COG1086	Polysaccharide biosynthesis protein
BT4G5_RS19555	COG1346	cytolysis
BT4G5_RS19565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BT4G5_RS19575	COG2188	Transcriptional regulator
BT4G5_RS19580	COG2723	6-phospho-beta-galactosidase activity
BT4G5_RS19585	COG0823	Involved in the tonB-independent uptake of proteins
BT4G5_RS19590	COG1404	Belongs to the peptidase S8 family
BT4G5_RS19595	COG3773	Cell wall hydrolase
BT4G5_RS19605	COG1368	sulfuric ester hydrolase activity
BT4G5_RS19610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BT4G5_RS19635	COG4550	Control of competence regulator ComK, YlbF/YmcA
BT4G5_RS19645	COG1013	pyruvate-flavodoxin oxidoreductase activity
BT4G5_RS19650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BT4G5_RS19650	COG0674	pyruvate-flavodoxin oxidoreductase activity
BT4G5_RS19660	COG2359	stage V sporulation protein S
BT4G5_RS19665	COG1692	metallophosphoesterase
BT4G5_RS19685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BT4G5_RS19690	COG1426	Protein conserved in bacteria
BT4G5_RS19705	COG0300	oxidoreductase activity
BT4G5_RS19710	COG0612	Peptidase, M16
BT4G5_RS19715	COG0612	Peptidase, M16
BT4G5_RS19720	COG1079	Belongs to the binding-protein-dependent transport system permease family
BT4G5_RS19725	COG4603	Belongs to the binding-protein-dependent transport system permease family
BT4G5_RS19730	COG3845	ABC transporter
BT4G5_RS19735	COG1744	ABC transporter substrate-binding protein PnrA-like
BT4G5_RS19740	COG2188	Transcriptional regulator
BT4G5_RS19755	COG0740	serine-type endopeptidase activity
BT4G5_RS19770	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BT4G5_RS19785	COG0527	aspartate kinase activity
BT4G5_RS19790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BT4G5_RS19795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BT4G5_RS19800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BT4G5_RS19805	COG1873	PFAM PRC-barrel domain
BT4G5_RS19810	COG0612	Peptidase, M16
BT4G5_RS19815	COG0726	polysaccharide deacetylase
BT4G5_RS19830	COG0196	riboflavin kinase activity
BT4G5_RS19840	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BT4G5_RS19845	COG1550	Protein conserved in bacteria
BT4G5_RS19855	COG1358	cellular component organization or biogenesis
BT4G5_RS19860	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BT4G5_RS19865	COG0195	Participates in both transcription termination and antitermination
BT4G5_RS19885	COG0750	zinc metalloprotease
BT4G5_RS19895	COG4589	Belongs to the CDS family
BT4G5_RS19950	COG4974	Belongs to the 'phage' integrase family
BT4G5_RS19960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BT4G5_RS19965	COG0758	DNA mediated transformation
BT4G5_RS19970	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BT4G5_RS20010	COG1837	Belongs to the UPF0109 family
BT4G5_RS20020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BT4G5_RS20030	COG0552	protein localization to endoplasmic reticulum
BT4G5_RS20035	COG1196	nuclear chromosome segregation
BT4G5_RS20045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BT4G5_RS20050	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS20055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BT4G5_RS20070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BT4G5_RS20075	COG1461	Dihydroxyacetone kinase
BT4G5_RS20080	COG1302	Protein conserved in bacteria
BT4G5_RS20095	COG1564	THIamine pyrophosphokinase
BT4G5_RS20100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BT4G5_RS20110	COG2815	serine threonine protein kinase
BT4G5_RS20110	COG0515	serine threonine protein kinase
BT4G5_RS20115	COG0631	protein serine/threonine phosphatase activity
BT4G5_RS20125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BT4G5_RS20125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BT4G5_RS20140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BT4G5_RS20145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BT4G5_RS20165	COG1561	YicC-like family, N-terminal region
BT4G5_RS20170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BT4G5_RS20180	COG0006	proline dipeptidase activity
BT4G5_RS20195	COG3069	C4-dicarboxylate transmembrane transporter activity
BT4G5_RS20255	COG0564	pseudouridine synthase activity
BT4G5_RS20275	COG3599	regulation of cell shape
BT4G5_RS20280	COG2302	S4 RNA-binding domain
BT4G5_RS20285	COG0762	integral membrane protein
BT4G5_RS20295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BT4G5_RS20305	COG1873	PFAM PRC-barrel domain
BT4G5_RS20310	COG1191	sigma factor activity
BT4G5_RS20315	COG1191	sigma factor activity
BT4G5_RS20325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BT4G5_RS20330	COG0849	cell division
BT4G5_RS20350	COG0772	Belongs to the SEDS family
BT4G5_RS20370	COG0768	penicillin binding
BT4G5_RS20375	COG0768	penicillin binding
BT4G5_RS20395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BT4G5_RS20410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BT4G5_RS20415	COG1399	metal-binding, possibly nucleic acid-binding protein
BT4G5_RS20425	COG3480	Lon protease (S16) C-terminal proteolytic domain
BT4G5_RS20430	COG1752	Esterase of the alpha-beta hydrolase superfamily
BT4G5_RS20435	COG3314	Sporulation integral membrane protein YlbJ
BT4G5_RS20445	COG0742	ribosomal rna small subunit methyltransferase
BT4G5_RS20460	COG3679	Belongs to the UPF0342 family
BT4G5_RS20465	COG0406	alpha-ribazole phosphatase activity
BT4G5_RS20480	COG2340	Cysteine-rich secretory protein family
BT4G5_RS20495	COG3336	cytochrome c oxidase
BT4G5_RS20530	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BT4G5_RS20535	COG0772	Belongs to the SEDS family
BT4G5_RS20545	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BT4G5_RS20550	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BT4G5_RS20560	COG4896	Protein conserved in bacteria
BT4G5_RS20575	COG1217	gtp-binding protein TYPA
BT4G5_RS20585	COG0483	inositol monophosphate 1-phosphatase activity
BT4G5_RS20605	COG1982	Orn Lys Arg decarboxylase major
BT4G5_RS20655	COG0022	dehydrogenase e1 component
BT4G5_RS20660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BT4G5_RS20675	COG0561	phosphatase activity
BT4G5_RS20685	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BT4G5_RS20690	COG0569	domain protein
BT4G5_RS20710	COG0583	DNA-binding transcription factor activity
BT4G5_RS20715	COG0517	IMP dehydrogenase activity
BT4G5_RS20725	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BT4G5_RS20735	COG4703	Protein of unknown function (DUF1797)
BT4G5_RS20750	COG2200	EAL domain
BT4G5_RS20755	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS20760	COG1408	metallophosphoesterase
BT4G5_RS20805	COG2814	Major facilitator Superfamily
BT4G5_RS20830	COG3209	COG3209 Rhs family protein
BT4G5_RS20840	COG2205	protein histidine kinase activity
BT4G5_RS20850	COG0436	Aminotransferase
BT4G5_RS20855	COG1609	Transcriptional regulator
BT4G5_RS20860	COG3833	ABC-type maltose transport systems, permease component
BT4G5_RS20865	COG1175	transmembrane transport
BT4G5_RS20870	COG2182	Extracellular solute-binding protein
BT4G5_RS20880	COG0366	Alpha amylase catalytic
BT4G5_RS20885	COG3842	ATPase activity
BT4G5_RS20920	COG0183	Belongs to the thiolase family
BT4G5_RS20955	COG1695	Transcriptional regulator
BT4G5_RS20960	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS20980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BT4G5_RS20985	COG0436	Aminotransferase
BT4G5_RS21020	COG2084	Dehydrogenase
BT4G5_RS21030	COG2199	diguanylate cyclase activity
BT4G5_RS21035	COG0778	Nitroreductase
BT4G5_RS21060	COG1263	PTS System
BT4G5_RS21060	COG2190	(PTS) system
BT4G5_RS21060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BT4G5_RS21065	COG3711	transcriptional antiterminator
BT4G5_RS21075	COG2188	Transcriptional regulator
BT4G5_RS21085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BT4G5_RS21115	COG1547	Domain of unknown function (DUF309)
BT4G5_RS21120	COG0456	acetyltransferase
BT4G5_RS21130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BT4G5_RS21135	COG4086	secreted protein
BT4G5_RS21140	COG0561	phosphatase activity
BT4G5_RS21145	COG0697	spore germination
BT4G5_RS21160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BT4G5_RS21205	COG1686	Belongs to the peptidase S11 family
BT4G5_RS21210	COG1725	Transcriptional regulator
BT4G5_RS21215	COG1131	(ABC) transporter
BT4G5_RS21230	COG1846	Transcriptional regulator
BT4G5_RS21245	COG0598	Magnesium transport protein CorA
BT4G5_RS21270	COG4974	Belongs to the 'phage' integrase family
BT4G5_RS21280	COG0735	belongs to the Fur family
BT4G5_RS21285	COG1300	Membrane
BT4G5_RS21305	COG0667	Aldo Keto reductase
BT4G5_RS21310	COG0656	L-ascorbic acid biosynthetic process
BT4G5_RS21315	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BT4G5_RS21315	COG0456	acetyltransferase
BT4G5_RS21325	COG0737	Belongs to the 5'-nucleotidase family
BT4G5_RS21325	COG4085	toxin activity
BT4G5_RS21325	COG1525	nuclease
BT4G5_RS21335	COG4085	toxin activity
BT4G5_RS21335	COG1525	nuclease
BT4G5_RS21335	COG0737	Belongs to the 5'-nucleotidase family
BT4G5_RS21345	COG0596	Alpha beta hydrolase
BT4G5_RS21350	COG2056	Na+-H+ antiporter family
BT4G5_RS21355	COG1609	Transcriptional regulator
BT4G5_RS21360	COG0456	acetyltransferase
BT4G5_RS21365	COG1073	alpha beta
BT4G5_RS21380	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BT4G5_RS21380	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BT4G5_RS21385	COG0307	riboflavin synthase, alpha
BT4G5_RS21415	COG2226	methyltransferase
BT4G5_RS21415	COG1073	alpha beta
BT4G5_RS21430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BT4G5_RS21440	COG1757	Na H antiporter
BT4G5_RS21445	COG0737	Belongs to the 5'-nucleotidase family
BT4G5_RS21455	COG1522	sequence-specific DNA binding
BT4G5_RS21500	COG0300	oxidoreductase activity
BT4G5_RS21505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT4G5_RS21510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BT4G5_RS21515	COG1760	l-serine dehydratase
BT4G5_RS21520	COG1760	l-serine dehydratase
BT4G5_RS21550	COG1285	pathogenesis
BT4G5_RS21565	COG2195	Cleaves the N-terminal amino acid of tripeptides
BT4G5_RS21570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS21585	COG1376	ErfK ybiS ycfS ynhG family protein
BT4G5_RS21590	COG4129	membrane
BT4G5_RS21595	COG1126	abc transporter atp-binding protein
BT4G5_RS21600	COG0765	amino acid transport
BT4G5_RS21605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BT4G5_RS21630	COG2323	membrane
BT4G5_RS21635	COG0772	Belongs to the SEDS family
BT4G5_RS21645	COG0508	dehydrogenase complex catalyzes the overall conversion of
BT4G5_RS21650	COG0022	dehydrogenase e1 component
BT4G5_RS21655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BT4G5_RS21660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BT4G5_RS21675	COG0280	phosphate acetyltransferase
BT4G5_RS21685	COG3829	transcription factor binding
BT4G5_RS21685	COG3290	protein histidine kinase activity
BT4G5_RS21695	COG0584	glycerophosphoryl diester phosphodiesterase
BT4G5_RS21700	COG3093	addiction module antidote protein HigA
BT4G5_RS21720	COG0750	zinc metalloprotease
BT4G5_RS21725	COG0497	DNA recombination
BT4G5_RS21735	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BT4G5_RS21745	COG0142	geranyltranstransferase activity
BT4G5_RS21770	COG1302	Protein conserved in bacteria
BT4G5_RS21775	COG0439	Biotin carboxylase
BT4G5_RS21780	COG0511	ligase activity, forming carbon-carbon bonds
BT4G5_RS21825	COG3854	ATPases associated with a variety of cellular activities
BT4G5_RS21850	COG0006	proline dipeptidase activity
BT4G5_RS21865	COG3872	metal-dependent enzyme
BT4G5_RS21875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BT4G5_RS21910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BT4G5_RS21920	COG1609	Transcriptional regulator
BT4G5_RS21930	COG2076	Multidrug Resistance protein
BT4G5_RS21935	COG2076	Multidrug Resistance protein
BT4G5_RS21970	COG1131	(ABC) transporter
BT4G5_RS21975	COG1725	Transcriptional regulator
BT4G5_RS22005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BT4G5_RS22070	COG1459	type II secretion system
BT4G5_RS22075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BT4G5_RS22130	COG0646	methionine synthase
BT4G5_RS22130	COG1410	methionine synthase
BT4G5_RS22135	COG0646	methionine synthase
BT4G5_RS22135	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BT4G5_RS22145	COG0626	cystathionine gamma-synthase activity
BT4G5_RS22150	COG0626	cystathionine gamma-synthase activity
BT4G5_RS22170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT4G5_RS22180	COG1940	carbohydrate kinase activity
BT4G5_RS22185	COG4483	Protein conserved in bacteria
BT4G5_RS22190	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BT4G5_RS22195	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BT4G5_RS22200	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BT4G5_RS22205	COG0704	Plays a role in the regulation of phosphate uptake
BT4G5_RS22215	COG0573	inorganic phosphate transmembrane transporter activity
BT4G5_RS22220	COG0573	inorganic phosphate transmembrane transporter activity
BT4G5_RS22225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BT4G5_RS22235	COG2801	Transposase and inactivated derivatives
BT4G5_RS22240	COG0768	penicillin binding
BT4G5_RS22245	COG0477	Major facilitator Superfamily
BT4G5_RS22250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BT4G5_RS22260	COG5521	maltodextrose utilization protein MalA
BT4G5_RS22275	COG0735	belongs to the Fur family
BT4G5_RS22280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BT4G5_RS22285	COG1121	(ABC) transporter
BT4G5_RS22290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT4G5_RS22320	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BT4G5_RS22325	COG2384	SAM-dependent methyltransferase
BT4G5_RS22335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BT4G5_RS22340	COG0358	DNA primase activity
BT4G5_RS22355	COG0517	IMP dehydrogenase activity
BT4G5_RS22370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BT4G5_RS22375	COG0295	cytidine deaminase activity
BT4G5_RS22380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BT4G5_RS22390	COG1480	7TM receptor with intracellular HD hydrolase
BT4G5_RS22395	COG1702	phosphate starvation-inducible protein PhoH
BT4G5_RS22420	COG1610	YqeY-like protein
BT4G5_RS22425	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BT4G5_RS22430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BT4G5_RS22435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BT4G5_RS22465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BT4G5_RS22470	COG1733	regulation of RNA biosynthetic process
BT4G5_RS22495	COG1466	dna polymerase III delta subunit
BT4G5_RS22505	COG0658	competence protein
BT4G5_RS22505	COG2333	competence protein COMEC
BT4G5_RS22510	COG2131	deaminase
BT4G5_RS22515	COG1555	photosystem II stabilization
BT4G5_RS22515	COG1596	polysaccharide export
BT4G5_RS22520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BT4G5_RS22525	COG2226	methyltransferase
BT4G5_RS22530	COG0799	negative regulation of ribosome biogenesis
BT4G5_RS22535	COG1713	HD superfamily hydrolase involved in NAD metabolism
BT4G5_RS22545	COG1534	Rna-binding protein
BT4G5_RS22555	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BT4G5_RS22560	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BT4G5_RS22585	COG1595	DNA-templated transcription, initiation
BT4G5_RS22595	COG0778	Nitroreductase
BT4G5_RS22600	COG2357	RelA SpoT domain protein
BT4G5_RS22610	COG1785	Belongs to the alkaline phosphatase family
BT4G5_RS22620	COG2267	carboxylic ester hydrolase activity
BT4G5_RS22660	COG3186	Phenylalanine-4-hydroxylase
BT4G5_RS22670	COG2514	catechol 2,3-dioxygenase activity
BT4G5_RS22675	COG2259	Doxx family
BT4G5_RS22715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT4G5_RS22725	COG1012	belongs to the aldehyde dehydrogenase family
BT4G5_RS22725	COG1454	alcohol dehydrogenase
BT4G5_RS22730	COG0626	cystathionine gamma-synthase activity
BT4G5_RS22735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BT4G5_RS22790	COG0826	peptidase U32
BT4G5_RS22795	COG0826	peptidase U32
BT4G5_RS22800	COG4122	O-methyltransferase activity
BT4G5_RS22805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BT4G5_RS22835	COG0628	permease
BT4G5_RS22855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BT4G5_RS22870	COG1104	cysteine desulfurase activity
BT4G5_RS22875	COG1959	2 iron, 2 sulfur cluster binding
BT4G5_RS22880	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BT4G5_RS22895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BT4G5_RS22920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BT4G5_RS22930	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BT4G5_RS22930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BT4G5_RS22935	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BT4G5_RS22940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BT4G5_RS22940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BT4G5_RS22950	COG2244	polysaccharide biosynthetic process
BT4G5_RS22955	COG2323	membrane
BT4G5_RS22965	COG1862	Preprotein translocase
BT4G5_RS22995	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BT4G5_RS23025	COG0157	Belongs to the NadC ModD family
BT4G5_RS23030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BT4G5_RS23035	COG1104	cysteine desulfurase activity
BT4G5_RS23040	COG1827	regulation of RNA biosynthetic process
BT4G5_RS23045	COG2258	MOSC domain
BT4G5_RS23050	COG0077	Prephenate dehydratase
BT4G5_RS23055	COG0577	efflux transmembrane transporter activity
BT4G5_RS23060	COG0577	efflux transmembrane transporter activity
BT4G5_RS23065	COG1136	(ABC) transporter
BT4G5_RS23070	COG5002	protein histidine kinase activity
BT4G5_RS23075	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS23085	COG3290	protein histidine kinase activity
BT4G5_RS23095	COG2868	ribosomal protein
BT4G5_RS23105	COG1530	ribonuclease E activity
BT4G5_RS23110	COG1994	Peptidase M50
BT4G5_RS23115	COG0739	heme binding
BT4G5_RS23120	COG2894	cell division
BT4G5_RS23140	COG1077	Cell shape determining protein MreB Mrl
BT4G5_RS23160	COG0285	dihydrofolate synthase activity
BT4G5_RS23175	COG1388	LysM domain
BT4G5_RS23185	COG0113	porphobilinogen synthase activity
BT4G5_RS23190	COG1587	Uroporphyrinogen-III synthase
BT4G5_RS23200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BT4G5_RS23210	COG1846	Transcriptional regulator
BT4G5_RS23215	COG1764	response to oxidative stress
BT4G5_RS23230	COG1067	ATP-dependent peptidase activity
BT4G5_RS23230	COG0470	DNA polymerase III
BT4G5_RS23365	COG0622	Phosphoesterase
BT4G5_RS23380	COG5401	PFAM Sporulation and spore germination
BT4G5_RS23395	COG2197	response regulator
BT4G5_RS23400	COG2233	PERMEase
BT4G5_RS23405	COG0402	S-adenosylhomocysteine deaminase activity
BT4G5_RS23410	COG1983	PspC domain protein
BT4G5_RS23415	COG1396	sequence-specific DNA binding
BT4G5_RS23420	COG0697	spore germination
BT4G5_RS23430	COG1959	2 iron, 2 sulfur cluster binding
BT4G5_RS23435	COG1668	transmembrane transport
BT4G5_RS23440	COG4152	abc transporter atp-binding protein
BT4G5_RS23445	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BT4G5_RS23450	COG1360	Flagellar Motor Protein
BT4G5_RS23455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BT4G5_RS23460	COG1876	peptidase activity
BT4G5_RS23465	COG0824	Thioesterase
BT4G5_RS23470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BT4G5_RS23475	COG1053	succinate dehydrogenase
BT4G5_RS23480	COG2009	succinate dehydrogenase
BT4G5_RS23485	COG1719	4-vinyl reductase, 4VR
BT4G5_RS23495	COG3118	belongs to the thioredoxin family
BT4G5_RS23500	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BT4G5_RS23505	COG2086	electron transfer activity
BT4G5_RS23510	COG1024	Enoyl-CoA hydratase
BT4G5_RS23515	COG1309	transcriptional regulator
BT4G5_RS23520	COG0318	PFAM AMP-dependent synthetase and ligase
BT4G5_RS23545	COG2318	DinB family
BT4G5_RS23575	COG1131	(ABC) transporter
BT4G5_RS23580	COG2205	protein histidine kinase activity
BT4G5_RS23585	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS23595	COG4895	conserved protein (DUF2196)
BT4G5_RS23600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BT4G5_RS23610	COG4509	Sortase family
BT4G5_RS23615	COG1120	ATPase activity
BT4G5_RS23630	COG5386	Cell surface protein
BT4G5_RS23640	COG5386	Cell surface protein
BT4G5_RS23645	COG1114	Component of the transport system for branched-chain amino acids
BT4G5_RS23650	COG1187	pseudouridine synthase activity
BT4G5_RS23665	COG1796	DNA polymerase
BT4G5_RS23665	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BT4G5_RS23670	COG1286	toxin biosynthetic process
BT4G5_RS23715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BT4G5_RS23725	COG1418	mRNA catabolic process
BT4G5_RS23745	COG2814	Major facilitator Superfamily
BT4G5_RS23750	COG1566	PFAM secretion protein HlyD family protein
BT4G5_RS23755	COG1309	transcriptional regulator
BT4G5_RS23760	COG1363	Peptidase, m42
BT4G5_RS23785	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BT4G5_RS23800	COG1484	DNA-dependent DNA replication
BT4G5_RS23805	COG3611	Membrane attachment protein
BT4G5_RS23815	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BT4G5_RS23820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BT4G5_RS23830	COG1971	Probably functions as a manganese efflux pump
BT4G5_RS23840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BT4G5_RS23840	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BT4G5_RS23845	COG5002	protein histidine kinase activity
BT4G5_RS23850	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS23870	COG0538	isocitrate dehydrogenase activity
BT4G5_RS23875	COG0372	Belongs to the citrate synthase family
BT4G5_RS23890	COG0628	permease
BT4G5_RS23895	COG3030	protein affecting phage T7 exclusion by the F plasmid
BT4G5_RS23920	COG1725	Transcriptional regulator
BT4G5_RS23925	COG0281	malic enzyme
BT4G5_RS23930	COG0587	DNA-directed DNA polymerase activity
BT4G5_RS23945	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BT4G5_RS23960	COG4109	DRTGG domain
BT4G5_RS23975	COG0006	proline dipeptidase activity
BT4G5_RS24010	COG0662	Cupin 2, conserved barrel domain protein
BT4G5_RS24025	COG1028	Short-chain dehydrogenase reductase Sdr
BT4G5_RS24030	COG0589	response to stress
BT4G5_RS24070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT4G5_RS24095	COG0827	DNA restriction-modification system
BT4G5_RS24100	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BT4G5_RS24105	COG3874	Sporulation protein YtfJ
BT4G5_RS24120	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BT4G5_RS24130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BT4G5_RS24145	COG1104	cysteine desulfurase activity
BT4G5_RS24155	COG0583	DNA-binding transcription factor activity
BT4G5_RS24160	COG0697	spore germination
BT4G5_RS24165	COG1309	transcriptional regulator
BT4G5_RS24170	COG1956	GAF domain-containing protein
BT4G5_RS24175	COG0626	cystathionine gamma-synthase activity
BT4G5_RS24215	COG1595	DNA-templated transcription, initiation
BT4G5_RS24225	COG0110	maltose O-acetyltransferase activity
BT4G5_RS24230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BT4G5_RS24235	COG0454	-acetyltransferase
BT4G5_RS24240	COG0517	IMP dehydrogenase activity
BT4G5_RS24245	COG0123	including yeast histone deacetylase and acetoin utilization protein
BT4G5_RS24260	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS24270	COG0666	response to abiotic stimulus
BT4G5_RS24275	COG2972	Histidine kinase
BT4G5_RS24275	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS24295	COG3279	Response regulator of the LytR AlgR family
BT4G5_RS24330	COG1609	Transcriptional regulator
BT4G5_RS24340	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BT4G5_RS24340	COG1605	Chorismate mutase
BT4G5_RS24345	COG4851	CamS sex pheromone cAM373 precursor
BT4G5_RS24350	COG3118	belongs to the thioredoxin family
BT4G5_RS24360	COG2309	aminopeptidase activity
BT4G5_RS24375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS24390	COG1674	ftsk spoiiie
BT4G5_RS24405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BT4G5_RS24415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BT4G5_RS24420	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BT4G5_RS24425	COG1363	Peptidase, m42
BT4G5_RS24435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT4G5_RS24450	COG0510	thiamine kinase activity
BT4G5_RS24455	COG1523	belongs to the glycosyl hydrolase 13 family
BT4G5_RS24470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BT4G5_RS24475	COG1349	DNA-binding transcription factor activity
BT4G5_RS24480	COG1187	pseudouridine synthase activity
BT4G5_RS24485	COG2244	polysaccharide biosynthetic process
BT4G5_RS24490	COG2081	HI0933 family
BT4G5_RS24495	COG2814	Major facilitator Superfamily
BT4G5_RS24505	COG3832	glyoxalase III activity
BT4G5_RS24525	COG1329	Transcriptional regulator
BT4G5_RS24550	COG0314	molybdopterin synthase activity
BT4G5_RS24555	COG1763	Mo-molybdopterin cofactor biosynthetic process
BT4G5_RS24560	COG0303	'Molybdopterin
BT4G5_RS24570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BT4G5_RS24575	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BT4G5_RS24595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BT4G5_RS24605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BT4G5_RS24655	COG2814	Major facilitator Superfamily
BT4G5_RS24660	COG0475	glutathione-regulated potassium exporter activity
BT4G5_RS24665	COG0490	domain, Protein
BT4G5_RS24670	COG0582	viral genome integration into host DNA
BT4G5_RS24680	COG1136	(ABC) transporter
BT4G5_RS24700	COG1242	4 iron, 4 sulfur cluster binding
BT4G5_RS24705	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BT4G5_RS24710	COG1794	racemase activity, acting on amino acids and derivatives
BT4G5_RS24730	COG2267	carboxylic ester hydrolase activity
BT4G5_RS24735	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BT4G5_RS24740	COG0671	phosphoesterase, PA-phosphatase related
BT4G5_RS24745	COG0438	transferase activity, transferring glycosyl groups
BT4G5_RS24770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS24815	COG0546	phosphoglycolate phosphatase activity
BT4G5_RS24820	COG1349	DNA-binding transcription factor activity
BT4G5_RS24830	COG5002	protein histidine kinase activity
BT4G5_RS24835	COG3852	Histidine kinase
BT4G5_RS24840	COG2267	carboxylic ester hydrolase activity
BT4G5_RS24845	COG1368	sulfuric ester hydrolase activity
BT4G5_RS24865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BT4G5_RS24870	COG1116	anion transmembrane transporter activity
BT4G5_RS24875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BT4G5_RS24895	COG0494	nUDIX hydrolase
BT4G5_RS24925	COG1854	S-ribosylhomocysteine lyase activity
BT4G5_RS24940	COG1271	oxidase subunit
BT4G5_RS24945	COG1294	oxidase, subunit
BT4G5_RS24955	COG2801	Transposase and inactivated derivatives
BT4G5_RS24970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT4G5_RS24990	COG1842	Phage shock protein A
BT4G5_RS25025	COG2801	Transposase and inactivated derivatives
BT4G5_RS25030	COG5002	protein histidine kinase activity
BT4G5_RS25035	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS25060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BT4G5_RS25065	COG1597	lipid kinase activity
BT4G5_RS25095	COG0586	Pfam SNARE associated Golgi protein
BT4G5_RS25105	COG0577	efflux transmembrane transporter activity
BT4G5_RS25110	COG1136	(ABC) transporter
BT4G5_RS25115	COG2207	Transcriptional regulator
BT4G5_RS25115	COG3708	Transcriptional regulator
BT4G5_RS25125	COG5658	integral membrane protein
BT4G5_RS25130	COG0640	Transcriptional regulator
BT4G5_RS25135	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS25140	COG2205	protein histidine kinase activity
BT4G5_RS25145	COG0577	efflux transmembrane transporter activity
BT4G5_RS25150	COG0577	efflux transmembrane transporter activity
BT4G5_RS25155	COG1136	(ABC) transporter
BT4G5_RS25160	COG0577	efflux transmembrane transporter activity
BT4G5_RS25185	COG2801	Transposase and inactivated derivatives
BT4G5_RS25195	COG2188	Transcriptional regulator
BT4G5_RS25215	COG3964	amidohydrolase
BT4G5_RS25235	COG4948	Mandelate Racemase Muconate Lactonizing
BT4G5_RS25255	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BT4G5_RS25260	COG0596	Alpha beta hydrolase
BT4G5_RS25270	COG1169	isochorismate synthase
BT4G5_RS25275	COG1575	Belongs to the MenA family. Type 1 subfamily
BT4G5_RS25280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BT4G5_RS25310	COG0058	SHG alpha-glucan phosphorylase activity
BT4G5_RS25320	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BT4G5_RS25440	COG0544	peptidyl-prolyl cis-trans isomerase activity
BT4G5_RS25475	COG1285	pathogenesis
BT4G5_RS25480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BT4G5_RS25500	COG2155	Conserved Protein
BT4G5_RS25505	COG1098	S1 RNA binding domain
BT4G5_RS25510	COG0436	Aminotransferase
BT4G5_RS25520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BT4G5_RS25525	COG2267	carboxylic ester hydrolase activity
BT4G5_RS25535	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BT4G5_RS25555	COG5018	Exonuclease
BT4G5_RS25560	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BT4G5_RS25585	COG2801	Transposase and inactivated derivatives
BT4G5_RS25590	COG2050	protein possibly involved in aromatic compounds catabolism
BT4G5_RS25600	COG1268	BioY protein
BT4G5_RS25605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BT4G5_RS25610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BT4G5_RS25625	COG3584	3D domain protein
BT4G5_RS25640	COG1252	NADH dehydrogenase
BT4G5_RS25670	COG1683	Conserved Protein
BT4G5_RS25725	COG1388	LysM domain
BT4G5_RS25725	COG3409	Peptidoglycan-binding domain 1 protein
BT4G5_RS25725	COG5632	N-Acetylmuramoyl-L-alanine amidase
BT4G5_RS25730	COG4824	toxin secretion phage lysis holin
BT4G5_RS25860	COG1191	sigma factor activity
BT4G5_RS25885	COG3645	SOS response
BT4G5_RS25885	COG3646	Phage regulatory protein
BT4G5_RS25900	COG3620	sequence-specific DNA binding
BT4G5_RS25940	COG2963	transposase activity
BT4G5_RS25945	COG2801	Transposase and inactivated derivatives
BT4G5_RS25950	COG0316	Belongs to the HesB IscA family
BT4G5_RS25965	COG1252	NADH dehydrogenase
BT4G5_RS25980	COG0390	transport system, permease component
BT4G5_RS25985	COG2824	Alkylphosphonate utilization operon protein PhnA
BT4G5_RS26030	COG4837	Protein of unknown function (DUF1462)
BT4G5_RS26035	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BT4G5_RS26045	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BT4G5_RS26050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BT4G5_RS26070	COG1358	cellular component organization or biogenesis
BT4G5_RS26080	COG2249	NAD(P)H dehydrogenase (quinone) activity
BT4G5_RS26085	COG0647	UMP catabolic process
BT4G5_RS26095	COG2445	Protein of unknown function DUF86
BT4G5_RS26100	COG1494	fructose-1,6-bisphosphatase
BT4G5_RS26125	COG4470	Protein conserved in bacteria
BT4G5_RS26135	COG0789	Transcriptional regulator
BT4G5_RS26140	COG4377	Putative membrane peptidase family (DUF2324)
BT4G5_RS26165	COG0739	heme binding
BT4G5_RS26175	COG3377	Domain of unknown function (DUF1805)
BT4G5_RS26180	COG0737	Belongs to the 5'-nucleotidase family
BT4G5_RS26185	COG2801	Transposase and inactivated derivatives
BT4G5_RS26210	COG5632	N-Acetylmuramoyl-L-alanine amidase
BT4G5_RS26415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BT4G5_RS26420	COG0582	viral genome integration into host DNA
BT4G5_RS26425	COG0719	Fe-S assembly protein
BT4G5_RS26430	COG0822	iron-sulfur transferase activity
BT4G5_RS26435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BT4G5_RS26440	COG0719	Fe-S assembly protein
BT4G5_RS26445	COG0396	ATPase activity
BT4G5_RS26450	COG1464	Belongs to the NlpA lipoprotein family
BT4G5_RS26455	COG1464	Belongs to the NlpA lipoprotein family
BT4G5_RS26460	COG2011	ABC-type metal ion transport system permease component
BT4G5_RS26475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BT4G5_RS26480	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BT4G5_RS26490	COG1393	Belongs to the ArsC family
BT4G5_RS26510	COG0039	L-malate dehydrogenase activity
BT4G5_RS26525	COG1309	transcriptional regulator
BT4G5_RS26530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BT4G5_RS26535	COG1960	acyl-CoA dehydrogenase activity
BT4G5_RS26540	COG0183	Belongs to the thiolase family
BT4G5_RS26545	COG1024	Enoyl-CoA hydratase
BT4G5_RS26545	COG1250	3-hydroxyacyl-CoA dehydrogenase
BT4G5_RS26555	COG1686	Belongs to the peptidase S11 family
BT4G5_RS26570	COG0011	TIGRFAM Protein of
BT4G5_RS26575	COG0840	transmembrane signaling receptor activity
BT4G5_RS26590	COG2814	Major facilitator Superfamily
BT4G5_RS26595	COG0531	amino acid
BT4G5_RS26615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BT4G5_RS26650	COG0586	Pfam SNARE associated Golgi protein
BT4G5_RS26660	COG1376	ErfK ybiS ycfS ynhG family protein
BT4G5_RS26665	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS26670	COG5002	protein histidine kinase activity
BT4G5_RS26700	COG0840	transmembrane signaling receptor activity
BT4G5_RS26705	COG2151	metal-sulfur cluster biosynthetic enzyme
BT4G5_RS26710	COG3227	Zinc metalloprotease (Elastase)
BT4G5_RS26730	COG0586	Pfam SNARE associated Golgi protein
BT4G5_RS26735	COG0475	glutathione-regulated potassium exporter activity
BT4G5_RS26740	COG0490	domain, Protein
BT4G5_RS26750	COG1115	amino acid carrier protein
BT4G5_RS26755	COG0783	Belongs to the Dps family
BT4G5_RS26770	COG1611	Belongs to the LOG family
BT4G5_RS26780	COG1528	Iron-storage protein
BT4G5_RS26785	COG2311	Membrane
BT4G5_RS26790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT4G5_RS26795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT4G5_RS26800	COG1115	amino acid carrier protein
BT4G5_RS26805	COG1115	amino acid carrier protein
BT4G5_RS26810	COG2910	NAD(P)H-binding
BT4G5_RS26825	COG0656	L-ascorbic acid biosynthetic process
BT4G5_RS26830	COG2814	Major facilitator Superfamily
BT4G5_RS26835	COG1733	regulation of RNA biosynthetic process
BT4G5_RS26845	COG1252	NADH dehydrogenase
BT4G5_RS26900	COG0488	(ABC) transporter
BT4G5_RS26905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BT4G5_RS26955	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS26990	COG0557	exoribonuclease II activity
BT4G5_RS26995	COG1647	Serine aminopeptidase, S33
BT4G5_RS27000	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BT4G5_RS27005	COG1346	cytolysis
BT4G5_RS27040	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BT4G5_RS27055	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BT4G5_RS27085	COG0457	Tetratricopeptide repeat
BT4G5_RS27090	COG1388	LysM domain
BT4G5_RS27090	COG3409	Peptidoglycan-binding domain 1 protein
BT4G5_RS27090	COG5632	N-Acetylmuramoyl-L-alanine amidase
BT4G5_RS27095	COG4824	toxin secretion phage lysis holin
BT4G5_RS27100	COG3547	Transposase (IS116 IS110 IS902 family)
BT4G5_RS27235	COG3331	DNA recombination
BT4G5_RS27315	COG3646	Phage regulatory protein
BT4G5_RS27340	COG0582	viral genome integration into host DNA
BT4G5_RS27365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BT4G5_RS27380	COG2323	membrane
BT4G5_RS27390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BT4G5_RS27400	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BT4G5_RS27410	COG1051	belongs to the nudix hydrolase family
BT4G5_RS27420	COG0492	ferredoxin-NADP+ reductase activity
BT4G5_RS27425	COG0457	Tetratricopeptide repeat
BT4G5_RS27430	COG0110	maltose O-acetyltransferase activity
BT4G5_RS27450	COG1950	PFAM Membrane protein of
BT4G5_RS27460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BT4G5_RS27465	COG0556	nucleotide-excision repair
BT4G5_RS27480	COG0789	Transcriptional regulator
BT4G5_RS27500	COG0583	DNA-binding transcription factor activity
BT4G5_RS27510	COG0655	NAD(P)H dehydrogenase (quinone) activity
BT4G5_RS27515	COG0488	(ABC) transporter
BT4G5_RS27525	COG1132	(ABC) transporter
BT4G5_RS27530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BT4G5_RS27535	COG3409	Peptidoglycan-binding domain 1 protein
BT4G5_RS27535	COG0793	Belongs to the peptidase S41A family
BT4G5_RS27540	COG2177	Part of the ABC transporter FtsEX involved in
BT4G5_RS27545	COG2884	Cell division ATP-binding protein ftsE
BT4G5_RS27560	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BT4G5_RS27575	COG1131	(ABC) transporter
BT4G5_RS27605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BT4G5_RS27610	COG1278	Cold shock
BT4G5_RS27615	COG1040	competence protein
BT4G5_RS27620	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BT4G5_RS27625	COG1388	LysM domain
BT4G5_RS27625	COG0791	NLP P60 protein
BT4G5_RS27630	COG1733	regulation of RNA biosynthetic process
BT4G5_RS27635	COG1307	EDD domain protein, DegV family
BT4G5_RS27640	COG1739	Uncharacterized protein family UPF0029
BT4G5_RS27645	COG1316	TRANSCRIPTIONal
BT4G5_RS27650	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BT4G5_RS27655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BT4G5_RS27660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BT4G5_RS27670	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BT4G5_RS27670	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BT4G5_RS27690	COG1486	melibiose metabolic process
BT4G5_RS27695	COG1447	Phosphotransferase system cellobiose-specific component IIA
BT4G5_RS27700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BT4G5_RS27710	COG1447	Phosphotransferase system cellobiose-specific component IIA
BT4G5_RS27720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BT4G5_RS27725	COG1301	dicarboxylic acid transport
BT4G5_RS27740	COG1511	domain protein
BT4G5_RS27745	COG0583	DNA-binding transcription factor activity
BT4G5_RS27750	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BT4G5_RS27760	COG1271	oxidase subunit
BT4G5_RS27765	COG1294	oxidase, subunit
BT4G5_RS27770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BT4G5_RS27780	COG1620	l-lactate permease
BT4G5_RS27795	COG2389	metal-binding protein
BT4G5_RS27805	COG1368	sulfuric ester hydrolase activity
BT4G5_RS27815	COG2801	Transposase and inactivated derivatives
BT4G5_RS27825	COG1388	LysM domain
BT4G5_RS27825	COG0791	NLP P60 protein
BT4G5_RS27830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BT4G5_RS27850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BT4G5_RS27855	COG1388	LysM domain
BT4G5_RS27855	COG3584	3D domain protein
BT4G5_RS27880	COG4715	Zinc finger, swim domain protein
BT4G5_RS27885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BT4G5_RS27925	COG0577	efflux transmembrane transporter activity
BT4G5_RS27930	COG1136	(ABC) transporter
BT4G5_RS27955	COG5002	protein histidine kinase activity
BT4G5_RS27960	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS27970	COG1316	TRANSCRIPTIONal
BT4G5_RS27975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BT4G5_RS27980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BT4G5_RS27985	COG1215	transferase activity, transferring glycosyl groups
BT4G5_RS27990	COG0463	Glycosyl transferase, family 2
BT4G5_RS27995	COG0438	transferase activity, transferring glycosyl groups
BT4G5_RS28005	COG1216	Glycosyl transferase, family 2
BT4G5_RS28020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BT4G5_RS28025	COG4464	protein tyrosine phosphatase activity
BT4G5_RS28030	COG0489	protein tyrosine kinase activity
BT4G5_RS28035	COG3944	biosynthesis protein
BT4G5_RS28040	COG0489	protein tyrosine kinase activity
BT4G5_RS28055	COG1609	Transcriptional regulator
BT4G5_RS28065	COG0739	heme binding
BT4G5_RS28080	COG3279	Response regulator of the LytR AlgR family
BT4G5_RS28085	COG2385	sporulation resulting in formation of a cellular spore
BT4G5_RS28100	COG4836	Membrane
BT4G5_RS28105	COG1007	ATP synthesis coupled electron transport
BT4G5_RS28110	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BT4G5_RS28115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BT4G5_RS28125	COG0839	Belongs to the complex I subunit 6 family
BT4G5_RS28145	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BT4G5_RS28160	COG5001	Diguanylate cyclase
BT4G5_RS28160	COG3300	MHYT domain
BT4G5_RS28210	COG0356	it plays a direct role in the translocation of protons across the membrane
BT4G5_RS28245	COG0698	ribose 5-phosphate isomerase
BT4G5_RS28260	COG2259	Doxx family
BT4G5_RS28265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BT4G5_RS28285	COG0009	L-threonylcarbamoyladenylate synthase
BT4G5_RS28320	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BT4G5_RS28330	COG1494	fructose-1,6-bisphosphatase
BT4G5_RS28350	COG4821	SIS domain
BT4G5_RS28360	COG3343	RNA polymerase activity
BT4G5_RS28370	COG1960	acyl-CoA dehydrogenase activity
BT4G5_RS28375	COG1960	acyl-CoA dehydrogenase activity
BT4G5_RS28380	COG1250	3-hydroxyacyl-CoA dehydrogenase
BT4G5_RS28385	COG0183	Belongs to the thiolase family
BT4G5_RS28390	COG2181	nitrate reductase activity
BT4G5_RS28390	COG0247	lactate metabolic process
BT4G5_RS28395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BT4G5_RS28405	COG5001	Diguanylate cyclase
BT4G5_RS28405	COG3300	MHYT domain
BT4G5_RS28420	COG3227	Zinc metalloprotease (Elastase)
BT4G5_RS28425	COG2197	response regulator
BT4G5_RS28430	COG4585	Histidine kinase
BT4G5_RS28435	COG0842	Transport permease protein
BT4G5_RS28440	COG1131	(ABC) transporter
BT4G5_RS28445	COG0024	Methionine aminopeptidase
BT4G5_RS28460	COG2234	aminopeptidase activity
BT4G5_RS28480	COG1595	DNA-templated transcription, initiation
BT4G5_RS28490	COG4506	Protein conserved in bacteria
BT4G5_RS28495	COG1619	proteins homologs of microcin C7 resistance protein MccF
BT4G5_RS28525	COG2814	Major facilitator Superfamily
BT4G5_RS28530	COG0789	Transcriptional regulator
BT4G5_RS28535	COG0584	glycerophosphoryl diester phosphodiesterase
BT4G5_RS28540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BT4G5_RS28550	COG1994	Peptidase M50
BT4G5_RS28560	COG1078	dGTPase activity
BT4G5_RS28565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BT4G5_RS28575	COG2801	Transposase and inactivated derivatives
BT4G5_RS28580	COG1120	ATPase activity
BT4G5_RS28585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT4G5_RS28590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT4G5_RS28610	COG0280	phosphate acetyltransferase
BT4G5_RS28625	COG3773	Cell wall hydrolase
BT4G5_RS28635	COG2363	Small membrane protein
BT4G5_RS28645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BT4G5_RS28650	COG2233	PERMEase
BT4G5_RS28655	COG0561	phosphatase activity
BT4G5_RS28660	COG2814	Major facilitator Superfamily
BT4G5_RS28675	COG1131	(ABC) transporter
BT4G5_RS28680	COG2755	lipolytic protein G-D-S-L family
BT4G5_RS28685	COG1609	Transcriptional regulator
BT4G5_RS28695	COG0460	homoserine dehydrogenase
BT4G5_RS28705	COG2873	o-acetylhomoserine
BT4G5_RS28715	COG1011	Hydrolase
BT4G5_RS28720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BT4G5_RS28730	COG2197	response regulator
BT4G5_RS28735	COG2203	Gaf domain
BT4G5_RS28735	COG4585	Histidine kinase
BT4G5_RS28740	COG0351	phosphomethylpyrimidine kinase
BT4G5_RS28745	COG3706	GGDEF domain
BT4G5_RS28750	COG2879	small protein
BT4G5_RS28755	COG1966	Carbon starvation protein
BT4G5_RS28760	COG3279	Response regulator of the LytR AlgR family
BT4G5_RS28765	COG0477	Major facilitator Superfamily
BT4G5_RS28775	COG0438	transferase activity, transferring glycosyl groups
BT4G5_RS28790	COG0840	transmembrane signaling receptor activity
BT4G5_RS28800	COG1607	acyl-coa hydrolase
BT4G5_RS28805	COG1216	Glycosyl transferase, family 2
BT4G5_RS28820	COG1216	Glycosyl transferase, family 2
BT4G5_RS28830	COG4485	Bacterial membrane protein, YfhO
BT4G5_RS28835	COG0463	Glycosyl transferase, family 2
BT4G5_RS28840	COG0488	(ABC) transporter
BT4G5_RS28845	COG1309	transcriptional regulator
BT4G5_RS28850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BT4G5_RS28860	COG0628	permease
BT4G5_RS28880	COG3275	phosphorelay sensor kinase activity
BT4G5_RS28885	COG2814	Major facilitator Superfamily
BT4G5_RS28890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BT4G5_RS28895	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BT4G5_RS28925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BT4G5_RS28930	COG1272	protein, Hemolysin III
BT4G5_RS28965	COG5002	protein histidine kinase activity
BT4G5_RS28980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BT4G5_RS28985	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BT4G5_RS28990	COG4853	Protein conserved in bacteria
BT4G5_RS29000	COG5002	protein histidine kinase activity
BT4G5_RS29005	COG0745	RESPONSE REGULATOR receiver
BT4G5_RS29035	COG0305	Participates in initiation and elongation during chromosome replication
BT4G5_RS29045	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BT4G5_RS29050	COG4241	membrane
BT4G5_RS29070	COG0012	GTP binding
BT4G5_RS29075	COG4481	Protein conserved in bacteria
BT4G5_RS29080	COG0668	transmembrane transport
BT4G5_RS29090	COG1475	DNA binding
BT4G5_RS29095	COG1192	Involved in chromosome partitioning
BT4G5_RS29120	COG1847	R3H domain protein
BT4G5_RS29135	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BT4G5_RS29145	COG0592	DNA-directed DNA polymerase activity
BT4G5_RS29150	COG2501	S4 domain
BT4G5_RS29160	COG0187	DNA topoisomerase II activity
BT4G5_RS29165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BT4G5_RS29200	COG0516	GMP reductase activity
BT4G5_RS29200	COG0517	IMP dehydrogenase activity
BT4G5_RS29205	COG1686	Belongs to the peptidase S11 family
BT4G5_RS29235	COG1428	Deoxynucleoside kinase
BT4G5_RS29240	COG1428	Deoxynucleoside kinase
BT4G5_RS29245	COG1335	isochorismatase
BT4G5_RS29255	COG0590	tRNA wobble adenosine to inosine editing
BT4G5_RS29260	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BT4G5_RS29315	COG1982	Orn Lys Arg decarboxylase major
BT4G5_RS29325	COG0470	DNA polymerase III
BT4G5_RS29330	COG1774	PSP1 C-terminal conserved region
BT4G5_RS29340	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BT4G5_RS29350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BT4G5_RS29355	COG2002	toxin-antitoxin pair type II binding
BT4G5_RS29365	COG0084	hydrolase, TatD family'
BT4G5_RS29385	COG4466	Protein conserved in bacteria
BT4G5_RS29400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BT4G5_RS29405	COG0251	oxidation-reduction process
BT4G5_RS29435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BT4G5_RS29440	COG2002	toxin-antitoxin pair type II binding
BT4G5_RS29445	COG2244	polysaccharide biosynthetic process
BT4G5_RS29450	COG3956	TIGRFAM MazG family protein
BT4G5_RS29455	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BT4G5_RS29475	COG1098	S1 RNA binding domain
BT4G5_RS29490	COG2208	phosphoserine phosphatase activity
BT4G5_RS29500	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BT4G5_RS29505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BT4G5_RS29520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BT4G5_RS29525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BT4G5_RS29530	COG0512	Glutamine amidotransferase of anthranilate synthase
BT4G5_RS29535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BT4G5_RS29540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BT4G5_RS29545	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BT4G5_RS29550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BT4G5_RS29555	COG1396	sequence-specific DNA binding
BT4G5_RS29560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BT4G5_RS29875	COG1609	Transcriptional regulator
BT4G5_RS29965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BT4G5_RS30010	COG0531	amino acid
BT4G5_RS30385	COG0642	Histidine kinase
BT4G5_RS30385	COG5002	protein histidine kinase activity
BT4G5_RS30705	COG1846	Transcriptional regulator
BT4G5_RS30710	COG4682	membrane
BT4G5_RS30735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BT4G5_RS30905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BT4G5_RS31255	COG0387	Pfam Sodium calcium exchanger
BT4G5_RS31750	COG0604	alcohol dehydrogenase
BT4G5_RS31995	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BT4G5_RS32000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BT4G5_RS32470	COG0697	spore germination
BT4G5_RS32540	COG0542	response to heat
BT4G5_RS32805	COG0201	protein transport
BT4G5_RS32810	COG0201	protein transport
BT4G5_RS32870	COG0860	N-Acetylmuramoyl-L-alanine amidase
BT4G5_RS33140	COG1609	Transcriptional regulator
BT4G5_RS33175	COG0488	(ABC) transporter
BT4G5_RS33250	COG4956	integral membrane protein (PIN domain superfamily)
BT4G5_RS33270	COG0215	cysteine-tRNA ligase activity
BT4G5_RS33770	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BT4G5_RS34250	COG0542	response to heat
BT4G5_RS34265	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BT4G5_RS34375	COG0542	response to heat
BT4G5_RS34485	COG0542	response to heat
BT4G5_RS34525	COG2376	Dihydroxyacetone kinase
BT4G5_RS34550	COG1396	sequence-specific DNA binding