locus-tag	class	description
NF53_RS00010	COG0592	DNA-directed DNA polymerase activity
NF53_RS00015	COG2501	S4 domain
NF53_RS00025	COG0187	DNA topoisomerase II activity
NF53_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NF53_RS00065	COG0517	IMP dehydrogenase activity
NF53_RS00065	COG0516	GMP reductase activity
NF53_RS00070	COG1686	Belongs to the peptidase S11 family
NF53_RS00100	COG1428	Deoxynucleoside kinase
NF53_RS00105	COG1428	Deoxynucleoside kinase
NF53_RS00110	COG1335	isochorismatase
NF53_RS00120	COG0590	tRNA wobble adenosine to inosine editing
NF53_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NF53_RS00180	COG1982	Orn Lys Arg decarboxylase major
NF53_RS00190	COG0470	DNA polymerase III
NF53_RS00195	COG1774	PSP1 C-terminal conserved region
NF53_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NF53_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NF53_RS00220	COG2002	toxin-antitoxin pair type II binding
NF53_RS00230	COG0084	hydrolase, TatD family'
NF53_RS00250	COG4466	Protein conserved in bacteria
NF53_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NF53_RS00270	COG0251	oxidation-reduction process
NF53_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NF53_RS00305	COG2002	toxin-antitoxin pair type II binding
NF53_RS00310	COG2244	polysaccharide biosynthetic process
NF53_RS00315	COG3956	TIGRFAM MazG family protein
NF53_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NF53_RS00340	COG1098	S1 RNA binding domain
NF53_RS00355	COG2208	phosphoserine phosphatase activity
NF53_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NF53_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NF53_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NF53_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NF53_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
NF53_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NF53_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NF53_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NF53_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NF53_RS00420	COG1396	sequence-specific DNA binding
NF53_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NF53_RS00455	COG3880	PFAM UvrB UvrC protein
NF53_RS00465	COG0542	response to heat
NF53_RS00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NF53_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
NF53_RS00500	COG1045	serine acetyltransferase
NF53_RS00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NF53_RS00520	COG3688	RNA-binding protein containing a PIN domain
NF53_RS00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NF53_RS00540	COG0250	Participates in transcription elongation, termination and antitermination
NF53_RS00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NF53_RS00565	COG2813	Specifically methylates the guanine in position
NF53_RS00580	COG1358	cellular component organization or biogenesis
NF53_RS00585	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NF53_RS00650	COG0255	Belongs to the universal ribosomal protein uL29 family
NF53_RS00710	COG0201	protein transport
NF53_RS00720	COG0024	Methionine aminopeptidase
NF53_RS00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NF53_RS00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NF53_RS00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
NF53_RS00795	COG0489	protein tyrosine kinase activity
NF53_RS00805	COG2194	sulfuric ester hydrolase activity
NF53_RS00810	COG0726	polysaccharide deacetylase
NF53_RS00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NF53_RS00895	COG4856	YbbR-like protein
NF53_RS00935	COG1028	Short-chain dehydrogenase reductase Sdr
NF53_RS00940	COG2011	ABC-type metal ion transport system permease component
NF53_RS00945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NF53_RS00950	COG1464	Belongs to the NlpA lipoprotein family
NF53_RS00955	COG0604	alcohol dehydrogenase
NF53_RS00965	COG0277	FAD linked oxidase domain protein
NF53_RS00970	COG2271	Major facilitator Superfamily
NF53_RS00980	COG2814	Major facilitator Superfamily
NF53_RS00995	COG2207	Transcriptional regulator
NF53_RS01010	COG4166	transmembrane transport
NF53_RS01015	COG4166	transmembrane transport
NF53_RS01020	COG0656	L-ascorbic acid biosynthetic process
NF53_RS01035	COG4149	molybdate abc transporter
NF53_RS01040	COG0725	ABC transporter, periplasmic molybdate-binding protein
NF53_RS01045	COG1910	domain protein
NF53_RS01065	COG0697	spore germination
NF53_RS01080	COG0204	Acyl-transferase
NF53_RS01090	COG1609	Transcriptional regulator
NF53_RS01100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF53_RS01125	COG5298	Protein conserved in bacteria
NF53_RS01150	COG0488	(ABC) transporter
NF53_RS01160	COG0747	negative chemotaxis
NF53_RS01165	COG0601	transmembrane transport
NF53_RS01170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NF53_RS01175	COG0444	Belongs to the ABC transporter superfamily
NF53_RS01180	COG4608	Belongs to the ABC transporter superfamily
NF53_RS01185	COG0561	phosphatase activity
NF53_RS01205	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NF53_RS01210	COG0179	Fumarylacetoacetate (FAA) hydrolase
NF53_RS01220	COG0531	amino acid
NF53_RS01225	COG2814	Major facilitator Superfamily
NF53_RS01235	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NF53_RS01245	COG4294	response to UV
NF53_RS01250	COG0705	Rhomboid family
NF53_RS01260	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NF53_RS01265	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NF53_RS01270	COG0864	Transcriptional regulator
NF53_RS01275	COG2337	Toxic component of a toxin-antitoxin (TA) module
NF53_RS01280	COG2183	response to ionizing radiation
NF53_RS01380	COG0802	atpase or kinase
NF53_RS01385	COG1214	PFAM Peptidase M22, glycoprotease
NF53_RS01390	COG0456	acetyltransferase
NF53_RS01400	COG0488	(ABC) transporter
NF53_RS01415	COG1266	CAAX protease self-immunity
NF53_RS01435	COG2252	PERMEase
NF53_RS01445	COG5002	protein histidine kinase activity
NF53_RS01470	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NF53_RS01510	COG2205	protein histidine kinase activity
NF53_RS01515	COG0745	RESPONSE REGULATOR receiver
NF53_RS01550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF53_RS01560	COG0463	Glycosyl transferase, family 2
NF53_RS01560	COG1216	Glycosyl transferase, family 2
NF53_RS01580	COG0697	spore germination
NF53_RS01610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NF53_RS01615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NF53_RS01620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NF53_RS01630	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NF53_RS01645	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NF53_RS01655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NF53_RS01665	COG0151	Belongs to the GarS family
NF53_RS01695	COG0210	DNA helicase
NF53_RS01705	COG4851	CamS sex pheromone cAM373 precursor
NF53_RS01720	COG1335	isochorismatase
NF53_RS01730	COG2011	ABC-type metal ion transport system permease component
NF53_RS01735	COG1464	Belongs to the NlpA lipoprotein family
NF53_RS01750	COG0003	Pfam Anion-transporting ATPase
NF53_RS01755	COG1846	Transcriptional regulator
NF53_RS01760	COG4682	membrane
NF53_RS01780	COG1597	lipid kinase activity
NF53_RS01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NF53_RS01805	COG1012	belongs to the aldehyde dehydrogenase family
NF53_RS01810	COG2076	Multidrug Resistance protein
NF53_RS01820	COG2309	aminopeptidase activity
NF53_RS01835	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NF53_RS01845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NF53_RS01860	COG4807	Protein conserved in bacteria
NF53_RS01885	COG1757	Na H antiporter
NF53_RS01890	COG1473	amidohydrolase
NF53_RS01905	COG0450	alkyl hydroperoxide reductase
NF53_RS01925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF53_RS01930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF53_RS01935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NF53_RS01945	COG0492	ferredoxin-NADP+ reductase activity
NF53_RS01960	COG0166	Belongs to the GPI family
NF53_RS01985	COG5002	protein histidine kinase activity
NF53_RS02005	COG3541	Predicted nucleotidyltransferase
NF53_RS02010	COG2814	Major facilitator Superfamily
NF53_RS02015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NF53_RS02015	COG0723	plastoquinol--plastocyanin reductase activity
NF53_RS02025	COG0765	amino acid transport
NF53_RS02030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NF53_RS02040	COG0840	transmembrane signaling receptor activity
NF53_RS02065	COG0549	Belongs to the carbamate kinase family
NF53_RS02070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NF53_RS02080	COG0277	FAD linked oxidase domain protein
NF53_RS02085	COG0366	Alpha amylase catalytic
NF53_RS02090	COG1263	PTS System
NF53_RS02090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF53_RS02090	COG2190	(PTS) system
NF53_RS02120	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NF53_RS02140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NF53_RS02150	COG1116	anion transmembrane transporter activity
NF53_RS02195	COG2270	Major facilitator Superfamily
NF53_RS02225	COG2310	stress, protein
NF53_RS02230	COG2310	stress, protein
NF53_RS02235	COG2310	stress, protein
NF53_RS02240	COG0861	Integral membrane protein TerC family
NF53_RS02250	COG3853	Toxic anion resistance protein (TelA)
NF53_RS02265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NF53_RS02275	COG1295	ribonuclease BN
NF53_RS02280	COG2217	Heavy metal translocating P-type atpase
NF53_RS02285	COG0697	spore germination
NF53_RS02295	COG0681	Belongs to the peptidase S26 family
NF53_RS02305	COG0586	Pfam SNARE associated Golgi protein
NF53_RS02320	COG3871	stress protein (general stress protein 26)
NF53_RS02325	COG0387	Pfam Sodium calcium exchanger
NF53_RS02335	COG0535	radical SAM domain protein
NF53_RS02355	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NF53_RS02360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NF53_RS02375	COG3829	transcription factor binding
NF53_RS02385	COG0833	amino acid
NF53_RS02390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF53_RS02425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF53_RS02425	COG1263	PTS System
NF53_RS02430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NF53_RS02445	COG0463	Glycosyl transferase, family 2
NF53_RS02455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NF53_RS02455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF53_RS02475	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NF53_RS02495	COG1228	amidohydrolase
NF53_RS02500	COG1090	epimerase
NF53_RS02530	COG1988	membrane-bound metal-dependent
NF53_RS02535	COG1194	a g-specific adenine glycosylase
NF53_RS02560	COG1132	(ABC) transporter
NF53_RS02565	COG4129	membrane
NF53_RS02570	COG0069	glutamate synthase activity
NF53_RS02570	COG0067	glutamate synthase
NF53_RS02570	COG0070	glutamate synthase
NF53_RS02580	COG4555	ABC transporter
NF53_RS02600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NF53_RS02605	COG0735	belongs to the Fur family
NF53_RS02725	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NF53_RS02750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NF53_RS02755	COG1716	ATPase activity
NF53_RS02755	COG5001	Diguanylate cyclase
NF53_RS02765	COG2766	serine protein kinase
NF53_RS02790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NF53_RS02800	COG1585	Membrane protein implicated in regulation of membrane protease activity
NF53_RS02805	COG2268	Band 7 protein
NF53_RS02815	COG3290	protein histidine kinase activity
NF53_RS02820	COG4565	transcriptional regulatory protein
NF53_RS02825	COG2851	Citrate transporter
NF53_RS02850	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NF53_RS02855	COG3842	ATPase activity
NF53_RS02865	COG0395	ABC-type sugar transport system, permease component
NF53_RS02875	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NF53_RS02880	COG0745	RESPONSE REGULATOR receiver
NF53_RS02885	COG5002	protein histidine kinase activity
NF53_RS02895	COG4990	cell redox homeostasis
NF53_RS02905	COG3290	protein histidine kinase activity
NF53_RS02910	COG4565	transcriptional regulatory protein
NF53_RS02915	COG3493	citrate carrier protein
NF53_RS02920	COG0281	malic enzyme
NF53_RS02930	COG0697	spore germination
NF53_RS02935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF53_RS02945	COG5002	protein histidine kinase activity
NF53_RS02950	COG0745	RESPONSE REGULATOR receiver
NF53_RS02965	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NF53_RS02970	COG3383	formate dehydrogenase (NAD+) activity
NF53_RS02975	COG2427	Protein of unknown function (DUF1641)
NF53_RS02990	COG0531	amino acid
NF53_RS02995	COG0640	Transcriptional regulator
NF53_RS03000	COG2217	Heavy metal translocating P-type atpase
NF53_RS03005	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NF53_RS03015	COG3227	Zinc metalloprotease (Elastase)
NF53_RS03035	COG2720	vancomycin resistance protein
NF53_RS03040	COG1316	TRANSCRIPTIONal
NF53_RS03045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NF53_RS03050	COG0346	lactoylglutathione lyase activity
NF53_RS03055	COG1253	flavin adenine dinucleotide binding
NF53_RS03060	COG1027	Aspartate ammonia-lyase
NF53_RS03065	COG1620	l-lactate permease
NF53_RS03080	COG3104	oligopeptide transport
NF53_RS03085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NF53_RS03090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF53_RS03095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF53_RS03105	COG2226	methyltransferase
NF53_RS03115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF53_RS03125	COG4548	von Willebrand factor, type A
NF53_RS03130	COG0714	Associated with various cellular activities
NF53_RS03150	COG0531	amino acid
NF53_RS03155	COG2188	Transcriptional regulator
NF53_RS03160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF53_RS03160	COG1263	PTS System
NF53_RS03165	COG0366	Alpha amylase catalytic
NF53_RS03180	COG0697	spore germination
NF53_RS03185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NF53_RS03190	COG1115	amino acid carrier protein
NF53_RS03200	COG1126	abc transporter atp-binding protein
NF53_RS03205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NF53_RS03210	COG0765	amino acid transport
NF53_RS03215	COG0765	amino acid transport
NF53_RS03220	COG0833	amino acid
NF53_RS03235	COG1595	DNA-templated transcription, initiation
NF53_RS03245	COG2378	regulation of single-species biofilm formation
NF53_RS03250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NF53_RS03255	COG5002	protein histidine kinase activity
NF53_RS03270	COG0659	secondary active sulfate transmembrane transporter activity
NF53_RS03285	COG2271	Major facilitator Superfamily
NF53_RS03290	COG1846	Transcriptional regulator
NF53_RS03295	COG0477	Major facilitator Superfamily
NF53_RS03300	COG1609	Transcriptional regulator
NF53_RS03305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NF53_RS03320	COG1172	Belongs to the binding-protein-dependent transport system permease family
NF53_RS03325	COG1879	ABC-type sugar transport system periplasmic component
NF53_RS03350	COG1063	alcohol dehydrogenase
NF53_RS03400	COG0840	transmembrane signaling receptor activity
NF53_RS03405	COG3583	domain protein
NF53_RS03405	COG3584	3D domain protein
NF53_RS03410	COG1476	TRANSCRIPTIONal
NF53_RS03430	COG3104	oligopeptide transport
NF53_RS03435	COG1114	Component of the transport system for branched-chain amino acids
NF53_RS03450	COG1113	amino acid transport
NF53_RS03455	COG2252	PERMEase
NF53_RS03470	COG2153	protein acetylation
NF53_RS03480	COG0475	glutathione-regulated potassium exporter activity
NF53_RS03480	COG0569	domain protein
NF53_RS03490	COG1845	cytochrome c oxidase, subunit III
NF53_RS03495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NF53_RS03505	COG0833	amino acid
NF53_RS03510	COG4990	cell redox homeostasis
NF53_RS03525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NF53_RS03530	COG0697	spore germination
NF53_RS03535	COG0531	amino acid
NF53_RS03550	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NF53_RS03555	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NF53_RS03560	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NF53_RS03560	COG1918	ferrous iron import across plasma membrane
NF53_RS03565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NF53_RS03570	COG0573	inorganic phosphate transmembrane transporter activity
NF53_RS03575	COG0581	inorganic phosphate transmembrane transporter activity
NF53_RS03580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NF53_RS03700	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NF53_RS03725	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NF53_RS03730	COG1116	anion transmembrane transporter activity
NF53_RS03735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NF53_RS03740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NF53_RS03745	COG0352	thiamine-phosphate diphosphorylase activity
NF53_RS03750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NF53_RS03755	COG2104	thiamine diphosphate biosynthetic process
NF53_RS03765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NF53_RS03770	COG0351	phosphomethylpyrimidine kinase
NF53_RS03810	COG2205	protein histidine kinase activity
NF53_RS03815	COG2814	Major facilitator Superfamily
NF53_RS03820	COG1846	Transcriptional regulator
NF53_RS03840	COG2252	PERMEase
NF53_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
NF53_RS03860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NF53_RS03865	COG1621	beta-fructofuranosidase activity
NF53_RS03870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF53_RS03870	COG1263	PTS System
NF53_RS03875	COG1609	Transcriptional regulator
NF53_RS03925	COG0778	Nitroreductase
NF53_RS03930	COG2719	SpoVR family
NF53_RS03940	COG3591	Belongs to the peptidase S1B family
NF53_RS03950	COG0446	pyridine nucleotide-disulphide oxidoreductase
NF53_RS03955	COG1937	Protein conserved in bacteria
NF53_RS03960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NF53_RS03960	COG0425	Belongs to the sulfur carrier protein TusA family
NF53_RS03965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NF53_RS03965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF53_RS03970	COG0425	Belongs to the sulfur carrier protein TusA family
NF53_RS03975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NF53_RS03975	COG0425	Belongs to the sulfur carrier protein TusA family
NF53_RS03985	COG2210	Belongs to the sulfur carrier protein TusA family
NF53_RS03990	COG0730	response to heat
NF53_RS04000	COG1316	TRANSCRIPTIONal
NF53_RS04005	COG0604	alcohol dehydrogenase
NF53_RS04010	COG1283	sodium-dependent phosphate transmembrane transporter activity
NF53_RS04025	COG3711	transcriptional antiterminator
NF53_RS04025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF53_RS04030	COG1447	Phosphotransferase system cellobiose-specific component IIA
NF53_RS04035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NF53_RS04060	COG3584	3D domain protein
NF53_RS04060	COG1388	LysM domain
NF53_RS04065	COG0577	efflux transmembrane transporter activity
NF53_RS04070	COG1136	(ABC) transporter
NF53_RS04080	COG5522	Integral membrane protein (intg_mem_TP0381)
NF53_RS04095	COG1114	Component of the transport system for branched-chain amino acids
NF53_RS04100	COG3546	catalase activity
NF53_RS04135	COG0586	Pfam SNARE associated Golgi protein
NF53_RS04170	COG0531	amino acid
NF53_RS04175	COG0475	glutathione-regulated potassium exporter activity
NF53_RS04185	COG1737	Transcriptional regulator
NF53_RS04195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF53_RS04195	COG1263	PTS System
NF53_RS04205	COG2259	Doxx family
NF53_RS04225	COG1522	sequence-specific DNA binding
NF53_RS04230	COG0165	Argininosuccinate lyase
NF53_RS04230	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NF53_RS04235	COG0300	oxidoreductase activity
NF53_RS04255	COG1309	transcriptional regulator
NF53_RS04260	COG2814	Major facilitator Superfamily
NF53_RS04285	COG1136	(ABC) transporter
NF53_RS04290	COG0577	efflux transmembrane transporter activity
NF53_RS04295	COG1136	(ABC) transporter
NF53_RS04300	COG0577	efflux transmembrane transporter activity
NF53_RS04315	COG1733	regulation of RNA biosynthetic process
NF53_RS04330	COG4533	DNA binding
NF53_RS04335	COG2211	Major facilitator Superfamily
NF53_RS04345	COG0693	protein deglycase activity
NF53_RS04350	COG0753	catalase activity
NF53_RS04360	COG0531	amino acid
NF53_RS04365	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NF53_RS04375	COG1012	belongs to the aldehyde dehydrogenase family
NF53_RS04385	COG1132	(ABC) transporter
NF53_RS04390	COG1132	(ABC) transporter
NF53_RS04395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NF53_RS04400	COG0765	amino acid transport
NF53_RS04405	COG1126	abc transporter atp-binding protein
NF53_RS04420	COG0189	ligase activity
NF53_RS04450	COG0028	Belongs to the TPP enzyme family
NF53_RS04455	COG3527	Alpha-acetolactate decarboxylase
NF53_RS04465	COG0561	phosphatase activity
NF53_RS04475	COG5632	N-Acetylmuramoyl-L-alanine amidase
NF53_RS04475	COG3409	Peptidoglycan-binding domain 1 protein
NF53_RS04480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NF53_RS04500	COG0659	secondary active sulfate transmembrane transporter activity
NF53_RS04505	COG2244	polysaccharide biosynthetic process
NF53_RS04525	COG1024	Enoyl-CoA hydratase
NF53_RS04545	COG1363	Peptidase, m42
NF53_RS04585	COG0601	transmembrane transport
NF53_RS04590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NF53_RS04595	COG0444	Belongs to the ABC transporter superfamily
NF53_RS04600	COG4608	Belongs to the ABC transporter superfamily
NF53_RS04610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF53_RS04725	COG0582	viral genome integration into host DNA
NF53_RS04730	COG0477	Major facilitator Superfamily
NF53_RS04735	COG3290	protein histidine kinase activity
NF53_RS04740	COG4565	transcriptional regulatory protein
NF53_RS04745	COG3181	Tripartite tricarboxylate transporter family receptor
NF53_RS04750	COG0494	nUDIX hydrolase
NF53_RS04765	COG0305	Participates in initiation and elongation during chromosome replication
NF53_RS04790	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NF53_RS04795	COG1288	antiporter activity
NF53_RS04810	COG0477	Major facilitator Superfamily
NF53_RS04825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS04900	COG1073	alpha beta
NF53_RS04955	COG1183	phosphatidylcholine synthase activity
NF53_RS04975	COG2376	Dihydroxyacetone kinase
NF53_RS04985	COG2376	Dihydroxyacetone kinase
NF53_RS05015	COG2373	Large extracellular alpha-helical protein
NF53_RS05085	COG1191	sigma factor activity
NF53_RS05095	COG2208	phosphoserine phosphatase activity
NF53_RS05100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NF53_RS05145	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NF53_RS05165	COG0420	3'-5' exonuclease activity
NF53_RS05170	COG4717	serine-type aminopeptidase activity
NF53_RS05180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NF53_RS05195	COG0346	lactoylglutathione lyase activity
NF53_RS05200	COG0346	lactoylglutathione lyase activity
NF53_RS05205	COG0457	Tetratricopeptide repeat
NF53_RS05215	COG2267	carboxylic ester hydrolase activity
NF53_RS05235	COG2140	Oxalate decarboxylase
NF53_RS05245	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NF53_RS05250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NF53_RS05260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NF53_RS05265	COG1695	Transcriptional regulator
NF53_RS05290	COG0772	Belongs to the SEDS family
NF53_RS05305	COG3973	AAA domain
NF53_RS05335	COG4980	gas vesicle protein
NF53_RS05340	COG0537	adenosine 5'-monophosphoramidase activity
NF53_RS05345	COG1131	(ABC) transporter
NF53_RS05350	COG4473	ABC transporter
NF53_RS05360	COG1309	transcriptional regulator
NF53_RS05370	COG3402	PFAM membrane-flanked domain
NF53_RS05375	COG3428	Bacterial PH domain
NF53_RS05410	COG0697	spore germination
NF53_RS05415	COG3402	PFAM membrane-flanked domain
NF53_RS05420	COG3428	Bacterial PH domain
NF53_RS05425	COG2329	Antibiotic biosynthesis monooxygenase
NF53_RS05430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF53_RS05445	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NF53_RS05480	COG1309	transcriptional regulator
NF53_RS05485	COG1511	domain protein
NF53_RS05505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS05510	COG1609	Transcriptional regulator
NF53_RS05520	COG1234	tRNA 3'-trailer cleavage
NF53_RS05525	COG0095	Lipoate-protein ligase
NF53_RS05540	COG0318	PFAM AMP-dependent synthetase and ligase
NF53_RS05550	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NF53_RS05560	COG4208	sulfate ABC transporter
NF53_RS05580	COG1408	metallophosphoesterase
NF53_RS05585	COG1078	dGTPase activity
NF53_RS05595	COG1595	DNA-templated transcription, initiation
NF53_RS05600	COG2207	Transcriptional regulator
NF53_RS05600	COG3708	Transcriptional regulator
NF53_RS05610	COG2205	protein histidine kinase activity
NF53_RS05615	COG0745	RESPONSE REGULATOR receiver
NF53_RS05635	COG0501	Belongs to the peptidase M48B family
NF53_RS05640	COG0840	transmembrane signaling receptor activity
NF53_RS05645	COG3693	PFAM glycoside hydrolase, family 10
NF53_RS05655	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NF53_RS05660	COG2224	Isocitrate lyase
NF53_RS05675	COG1278	Cold shock
NF53_RS05695	COG0398	Pfam SNARE associated Golgi protein
NF53_RS05755	COG0179	Fumarylacetoacetate (FAA) hydrolase
NF53_RS05780	COG0367	asparagine synthase
NF53_RS05790	COG0753	catalase activity
NF53_RS05795	COG0004	ammonium transporteR
NF53_RS05815	COG2996	Protein conserved in bacteria
NF53_RS05830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF53_RS05845	COG0561	phosphatase activity
NF53_RS05870	COG2267	carboxylic ester hydrolase activity
NF53_RS05885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NF53_RS05890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NF53_RS05895	COG5504	Zn-dependent protease
NF53_RS05905	COG0180	Tryptophanyl-tRNA synthetase
NF53_RS05915	COG4166	transmembrane transport
NF53_RS05920	COG0601	transmembrane transport
NF53_RS05925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NF53_RS05930	COG0444	Belongs to the ABC transporter superfamily
NF53_RS05935	COG4608	Belongs to the ABC transporter superfamily
NF53_RS05940	COG0534	Mate efflux family protein
NF53_RS05945	COG4166	transmembrane transport
NF53_RS05965	COG0861	Integral membrane protein TerC family
NF53_RS05985	COG1164	Oligoendopeptidase f
NF53_RS06000	COG2346	COG2346, Truncated hemoglobins
NF53_RS06005	COG4116	CYTH
NF53_RS06015	COG2357	RelA SpoT domain protein
NF53_RS06025	COG0564	pseudouridine synthase activity
NF53_RS06040	COG0772	Belongs to the SEDS family
NF53_RS06045	COG1216	Glycosyl transferase, family 2
NF53_RS06065	COG0457	Tetratricopeptide repeat
NF53_RS06065	COG0463	Glycosyl transferase, family 2
NF53_RS06085	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NF53_RS06100	COG1091	dTDP-4-dehydrorhamnose reductase activity
NF53_RS06145	COG2153	protein acetylation
NF53_RS06155	COG2382	esterase
NF53_RS06175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NF53_RS06190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NF53_RS06190	COG0512	Glutamine amidotransferase of anthranilate synthase
NF53_RS06225	COG1620	l-lactate permease
NF53_RS06230	COG5634	Uncharacterized conserved protein (DUF2278)
NF53_RS06280	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF53_RS06390	COG4974	Belongs to the 'phage' integrase family
NF53_RS06415	COG1686	Belongs to the peptidase S11 family
NF53_RS06420	COG0681	Belongs to the peptidase S26 family
NF53_RS06455	COG1012	belongs to the aldehyde dehydrogenase family
NF53_RS06465	COG1176	ABC-type spermidine putrescine transport system, permease component I
NF53_RS06470	COG1177	transmembrane transport
NF53_RS06485	COG2409	Drug exporters of the RND superfamily
NF53_RS06495	COG0564	pseudouridine synthase activity
NF53_RS06505	COG2340	Cysteine-rich secretory protein family
NF53_RS06510	COG0247	lactate metabolic process
NF53_RS06515	COG0277	FAD linked oxidase domain protein
NF53_RS06520	COG3835	regulator
NF53_RS06530	COG0745	RESPONSE REGULATOR receiver
NF53_RS06535	COG5002	protein histidine kinase activity
NF53_RS06540	COG2186	Transcriptional regulator
NF53_RS06560	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NF53_RS06570	COG2116	formate transmembrane transporter activity
NF53_RS06575	COG0861	Integral membrane protein TerC family
NF53_RS06580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NF53_RS06590	COG2030	dehydratase
NF53_RS06610	COG1028	Short-chain dehydrogenase reductase Sdr
NF53_RS06615	COG3243	poly(R)-hydroxyalkanoic acid synthase
NF53_RS06625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NF53_RS06640	COG1840	ABC-type Fe3 transport system, periplasmic component
NF53_RS06645	COG3842	ATPase activity
NF53_RS06670	COG1349	DNA-binding transcription factor activity
NF53_RS06685	COG0235	Class ii aldolase
NF53_RS06695	COG2861	carbohydrate metabolic process
NF53_RS06705	COG3852	Histidine kinase
NF53_RS06710	COG1846	Transcriptional regulator
NF53_RS06720	COG2318	DinB family
NF53_RS06730	COG5002	protein histidine kinase activity
NF53_RS06740	COG0720	synthase
NF53_RS06755	COG4873	Protein conserved in bacteria
NF53_RS06795	COG1780	Probably involved in ribonucleotide reductase function
NF53_RS06800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NF53_RS06805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NF53_RS06810	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NF53_RS06815	COG1725	Transcriptional regulator
NF53_RS06820	COG1131	(ABC) transporter
NF53_RS06830	COG1131	(ABC) transporter
NF53_RS06840	COG1266	CAAX protease self-immunity
NF53_RS06850	COG1522	sequence-specific DNA binding
NF53_RS06860	COG1335	isochorismatase
NF53_RS06870	COG1619	proteins homologs of microcin C7 resistance protein MccF
NF53_RS06875	COG2070	2-Nitropropane dioxygenase
NF53_RS06880	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NF53_RS06890	COG1696	Membrane protein involved in D-alanine export
NF53_RS06915	COG0716	FMN binding
NF53_RS06965	COG1846	Transcriptional regulator
NF53_RS06975	COG1301	dicarboxylic acid transport
NF53_RS06980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NF53_RS06985	COG4709	membrane
NF53_RS06990	COG3874	Sporulation protein YtfJ
NF53_RS07020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NF53_RS07025	COG0028	Belongs to the TPP enzyme family
NF53_RS07030	COG0440	acetolactate synthase activity
NF53_RS07105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NF53_RS07120	COG1183	phosphatidylcholine synthase activity
NF53_RS07125	COG1368	sulfuric ester hydrolase activity
NF53_RS07135	COG0019	diaminopimelate decarboxylase activity
NF53_RS07155	COG0529	Catalyzes the synthesis of activated sulfate
NF53_RS07160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NF53_RS07180	COG1648	precorrin-2 dehydrogenase activity
NF53_RS07190	COG0733	neurotransmitter:sodium symporter activity
NF53_RS07210	COG1757	Na H antiporter
NF53_RS07225	COG4758	membrane
NF53_RS07230	COG4585	Histidine kinase
NF53_RS07235	COG2197	response regulator
NF53_RS07245	COG1114	Component of the transport system for branched-chain amino acids
NF53_RS07300	COG0730	response to heat
NF53_RS07305	COG0306	phosphate transporter
NF53_RS07310	COG1392	Phosphate transport regulator
NF53_RS07315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF53_RS07330	COG3852	Histidine kinase
NF53_RS07335	COG1801	Protein of unknown function DUF72
NF53_RS07345	COG0582	viral genome integration into host DNA
NF53_RS07350	COG5002	protein histidine kinase activity
NF53_RS07365	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NF53_RS07365	COG0392	lysyltransferase activity
NF53_RS07380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NF53_RS07385	COG1686	Belongs to the peptidase S11 family
NF53_RS07390	COG2715	membrane protein required for spore maturation
NF53_RS07395	COG0700	Nucleoside recognition
NF53_RS07400	COG1187	pseudouridine synthase activity
NF53_RS07410	COG1333	cytochrome c biogenesis protein
NF53_RS07415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NF53_RS07420	COG0745	RESPONSE REGULATOR receiver
NF53_RS07425	COG5002	protein histidine kinase activity
NF53_RS07430	COG2096	Adenosyltransferase
NF53_RS07445	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NF53_RS07450	COG1141	Ferredoxin
NF53_RS07460	COG0514	ATP-dependent DNA helicase (RecQ)
NF53_RS07465	COG1266	CAAX protease self-immunity
NF53_RS07475	COG1408	metallophosphoesterase
NF53_RS07480	COG0789	Transcriptional regulator
NF53_RS07490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NF53_RS07510	COG0492	ferredoxin-NADP+ reductase activity
NF53_RS07515	COG0252	asparaginase activity
NF53_RS07590	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NF53_RS07605	COG0142	geranyltranstransferase activity
NF53_RS07615	COG0142	geranyltranstransferase activity
NF53_RS07640	COG0457	Tetratricopeptide repeat
NF53_RS07660	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NF53_RS07665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NF53_RS07665	COG2010	Cytochrome c
NF53_RS07670	COG4347	Protein of unknown function (DUF1405)
NF53_RS07685	COG2738	Putative neutral zinc metallopeptidase
NF53_RS07695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF53_RS07700	COG1694	Mazg nucleotide pyrophosphohydrolase
NF53_RS07720	COG0438	transferase activity, transferring glycosyl groups
NF53_RS07760	COG1199	ATP-dependent helicase activity
NF53_RS07760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NF53_RS07780	COG3935	DnaD domain protein
NF53_RS07785	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NF53_RS07795	COG4499	WXG100 protein secretion system (Wss), protein YukC
NF53_RS07795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF53_RS07845	COG0116	Belongs to the methyltransferase superfamily
NF53_RS07855	COG1199	ATP-dependent helicase activity
NF53_RS07860	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NF53_RS07870	COG0024	Methionine aminopeptidase
NF53_RS07880	COG2233	PERMEase
NF53_RS07885	COG2311	Membrane
NF53_RS07890	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NF53_RS07900	COG0456	acetyltransferase
NF53_RS07940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NF53_RS07955	COG3944	biosynthesis protein
NF53_RS07965	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NF53_RS07980	COG1215	transferase activity, transferring glycosyl groups
NF53_RS07985	COG0438	transferase activity, transferring glycosyl groups
NF53_RS08000	COG0454	-acetyltransferase
NF53_RS08020	COG0328	RNA-DNA hybrid ribonuclease activity
NF53_RS08055	COG3403	YqcI/YcgG family
NF53_RS08060	COG1280	lysine exporter protein (LysE YggA)
NF53_RS08080	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NF53_RS08085	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NF53_RS08095	COG0475	glutathione-regulated potassium exporter activity
NF53_RS08100	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NF53_RS08105	COG4978	Transcriptional regulator
NF53_RS08105	COG0789	Transcriptional regulator
NF53_RS08115	COG2323	membrane
NF53_RS08120	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NF53_RS08160	COG1923	regulation of RNA biosynthetic process
NF53_RS08170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NF53_RS08175	COG1360	Flagellar Motor Protein
NF53_RS08180	COG2201	protein-glutamate methylesterase activity
NF53_RS08185	COG2198	Histidine kinase
NF53_RS08185	COG0643	Histidine kinase
NF53_RS08190	COG1776	CheC inhibitor of MCP methylation
NF53_RS08190	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NF53_RS08205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NF53_RS08225	COG1256	bacterial-type flagellum assembly
NF53_RS08230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NF53_RS08250	COG1815	bacterial-type flagellum-dependent cell motility
NF53_RS08255	COG1558	bacterial-type flagellum-dependent cell motility
NF53_RS08265	COG1766	The M ring may be actively involved in energy transduction
NF53_RS08270	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NF53_RS08280	COG1157	protein secretion by the type III secretion system
NF53_RS08300	COG1749	Flagellar hook protein flgE
NF53_RS08315	COG0835	chemotaxis
NF53_RS08315	COG0784	Response regulator, receiver
NF53_RS08325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NF53_RS08330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NF53_RS08335	COG0741	lytic transglycosylase activity
NF53_RS08345	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NF53_RS08350	COG1776	CheC inhibitor of MCP methylation
NF53_RS08350	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NF53_RS08360	COG1338	Plays a role in the flagellum-specific transport system
NF53_RS08365	COG1987	bacterial-type flagellum assembly
NF53_RS08375	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NF53_RS08380	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NF53_RS08385	COG1419	protein localization to endoplasmic reticulum
NF53_RS08390	COG4786	Flagellar basal body rod
NF53_RS08395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NF53_RS08430	COG2329	Antibiotic biosynthesis monooxygenase
NF53_RS08455	COG0583	DNA-binding transcription factor activity
NF53_RS08500	COG0406	alpha-ribazole phosphatase activity
NF53_RS08530	COG0367	asparagine synthase
NF53_RS08560	COG1802	Transcriptional regulator
NF53_RS08565	COG0697	spore germination
NF53_RS08575	COG0523	cobalamin synthesis protein
NF53_RS08580	COG0701	Predicted permease
NF53_RS08595	COG1757	Na H antiporter
NF53_RS08600	COG0789	Transcriptional regulator
NF53_RS08635	COG0534	Mate efflux family protein
NF53_RS08640	COG3340	Belongs to the peptidase S51 family
NF53_RS08660	COG0785	Cytochrome C biogenesis protein
NF53_RS08665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF53_RS08675	COG0457	Tetratricopeptide repeat
NF53_RS08695	COG2733	membrane
NF53_RS08730	COG1131	(ABC) transporter
NF53_RS08750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NF53_RS08755	COG0528	UMP kinase activity
NF53_RS08765	COG1027	Aspartate ammonia-lyase
NF53_RS08770	COG0281	malic enzyme
NF53_RS08775	COG4191	Histidine kinase
NF53_RS08780	COG0784	Response regulator, receiver
NF53_RS08785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NF53_RS08855	COG1695	Transcriptional regulator
NF53_RS08865	COG0477	Major facilitator Superfamily
NF53_RS08875	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NF53_RS08880	COG2223	nitrite transmembrane transporter activity
NF53_RS08885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NF53_RS08905	COG0733	neurotransmitter:sodium symporter activity
NF53_RS08915	COG5566	PFAM Mor transcription activator
NF53_RS08920	COG2323	membrane
NF53_RS08940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NF53_RS08950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NF53_RS08955	COG0028	Belongs to the TPP enzyme family
NF53_RS08975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NF53_RS09000	COG2814	Major facilitator Superfamily
NF53_RS09005	COG3384	dioxygenase
NF53_RS09015	COG3279	Response regulator of the LytR AlgR family
NF53_RS09020	COG0427	acetyl-CoA hydrolase
NF53_RS09040	COG4166	transmembrane transport
NF53_RS09045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS09050	COG0745	RESPONSE REGULATOR receiver
NF53_RS09065	COG1914	H( )-stimulated, divalent metal cation uptake system
NF53_RS09080	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NF53_RS09090	COG0531	amino acid
NF53_RS09125	COG1309	transcriptional regulator
NF53_RS09130	COG2390	Transcriptional regulator
NF53_RS09140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NF53_RS09145	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NF53_RS09160	COG4846	Membrane protein involved in cytochrome C biogenesis
NF53_RS09185	COG0006	proline dipeptidase activity
NF53_RS09195	COG2132	Multicopper oxidase
NF53_RS09205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NF53_RS09225	COG1114	Component of the transport system for branched-chain amino acids
NF53_RS09235	COG2372	response to copper ion
NF53_RS09235	COG1276	copper resistance
NF53_RS09240	COG4549	nuclear export factor GLE1
NF53_RS09245	COG0697	spore germination
NF53_RS09250	COG0583	DNA-binding transcription factor activity
NF53_RS09255	COG1959	2 iron, 2 sulfur cluster binding
NF53_RS09260	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NF53_RS09265	COG0778	Nitroreductase
NF53_RS09290	COG1231	oxidoreductase activity
NF53_RS09295	COG0523	cobalamin synthesis protein
NF53_RS09305	COG0411	ABC transporter
NF53_RS09325	COG0583	DNA-binding transcription factor activity
NF53_RS09355	COG1271	oxidase subunit
NF53_RS09360	COG1294	oxidase, subunit
NF53_RS09365	COG4988	ABC transporter
NF53_RS09370	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NF53_RS09380	COG1216	Glycosyl transferase, family 2
NF53_RS09420	COG1686	Belongs to the peptidase S11 family
NF53_RS09435	COG1388	LysM domain
NF53_RS09435	COG0791	NLP P60 protein
NF53_RS09445	COG1132	(ABC) transporter
NF53_RS09450	COG0745	RESPONSE REGULATOR receiver
NF53_RS09455	COG5002	protein histidine kinase activity
NF53_RS09460	COG0300	oxidoreductase activity
NF53_RS09490	COG0460	homoserine dehydrogenase
NF53_RS09515	COG1316	TRANSCRIPTIONal
NF53_RS09525	COG0745	RESPONSE REGULATOR receiver
NF53_RS09530	COG5002	protein histidine kinase activity
NF53_RS09545	COG1285	pathogenesis
NF53_RS09550	COG1247	-acetyltransferase
NF53_RS09570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF53_RS09580	COG1082	Xylose isomerase domain protein TIM barrel
NF53_RS09590	COG2814	Major facilitator Superfamily
NF53_RS09595	COG1279	arginine transmembrane transporter activity
NF53_RS09600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF53_RS09610	COG1752	Esterase of the alpha-beta hydrolase superfamily
NF53_RS09645	COG0577	efflux transmembrane transporter activity
NF53_RS09650	COG2002	toxin-antitoxin pair type II binding
NF53_RS09655	COG1404	Belongs to the peptidase S8 family
NF53_RS09690	COG0840	transmembrane signaling receptor activity
NF53_RS09710	COG3949	Membrane
NF53_RS09715	COG0783	Belongs to the Dps family
NF53_RS09730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF53_RS09740	COG1231	oxidoreductase activity
NF53_RS09745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS09750	COG4989	oxidoreductase activity
NF53_RS09755	COG0523	cobalamin synthesis protein
NF53_RS09760	COG0456	acetyltransferase
NF53_RS09765	COG0803	Belongs to the bacterial solute-binding protein 9 family
NF53_RS09775	COG0702	epimerase
NF53_RS09785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NF53_RS09795	COG4166	transmembrane transport
NF53_RS09820	COG5337	Spore coat protein CotH
NF53_RS09825	COG1051	belongs to the nudix hydrolase family
NF53_RS09830	COG0586	Pfam SNARE associated Golgi protein
NF53_RS09835	COG2244	polysaccharide biosynthetic process
NF53_RS09845	COG0701	Predicted permease
NF53_RS09850	COG3689	TIGRFAM TIGR03943 family protein
NF53_RS09855	COG1607	acyl-coa hydrolase
NF53_RS09860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NF53_RS09875	COG0702	epimerase
NF53_RS09880	COG2839	Protein conserved in bacteria
NF53_RS09885	COG1253	flavin adenine dinucleotide binding
NF53_RS09900	COG1114	Component of the transport system for branched-chain amino acids
NF53_RS09905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NF53_RS09925	COG0860	N-Acetylmuramoyl-L-alanine amidase
NF53_RS09935	COG1876	peptidase activity
NF53_RS09950	COG2211	Major facilitator Superfamily
NF53_RS09965	COG0860	N-Acetylmuramoyl-L-alanine amidase
NF53_RS09975	COG0561	phosphatase activity
NF53_RS09990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NF53_RS10000	COG1819	glycosyl
NF53_RS10005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF53_RS10010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF53_RS10040	COG0456	acetyltransferase
NF53_RS10075	COG4499	WXG100 protein secretion system (Wss), protein YukC
NF53_RS10135	COG3874	Sporulation protein YtfJ
NF53_RS10160	COG2226	methyltransferase
NF53_RS10180	COG1082	Xylose isomerase domain protein TIM barrel
NF53_RS10185	COG0346	lactoylglutathione lyase activity
NF53_RS10195	COG0604	alcohol dehydrogenase
NF53_RS10200	COG1595	DNA-templated transcription, initiation
NF53_RS10225	COG0386	Belongs to the glutathione peroxidase family
NF53_RS10230	COG1305	Transglutaminase-like
NF53_RS10235	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NF53_RS10240	COG0714	Associated with various cellular activities
NF53_RS10245	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NF53_RS10250	COG1140	nitrate reductase beta subunit
NF53_RS10255	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NF53_RS10260	COG2181	nitrate reductase activity
NF53_RS10265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NF53_RS10270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NF53_RS10275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NF53_RS10280	COG0303	'Molybdopterin
NF53_RS10285	COG0314	molybdopterin synthase activity
NF53_RS10295	COG2223	nitrite transmembrane transporter activity
NF53_RS10315	COG1648	precorrin-2 dehydrogenase activity
NF53_RS10325	COG1587	Uroporphyrinogen-III synthase
NF53_RS10325	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NF53_RS10330	COG2146	nitrite reductase [NAD(P)H] activity
NF53_RS10335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NF53_RS10340	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
NF53_RS10375	COG2359	stage V sporulation protein S
NF53_RS10395	COG0457	Tetratricopeptide repeat
NF53_RS10410	COG2856	Zn peptidase
NF53_RS10425	COG1396	sequence-specific DNA binding
NF53_RS10475	COG0662	Cupin 2, conserved barrel domain protein
NF53_RS10500	COG0582	viral genome integration into host DNA
NF53_RS10535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NF53_RS10545	COG5484	DNA packaging
NF53_RS10550	COG1783	phage Terminase large subunit
NF53_RS10565	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NF53_RS10690	COG0457	Tetratricopeptide repeat
NF53_RS10705	COG1418	mRNA catabolic process
NF53_RS10710	COG0488	(ABC) transporter
NF53_RS10725	COG0629	single-stranded DNA binding
NF53_RS10735	COG1413	lyase activity
NF53_RS10750	COG2521	methyltransferase
NF53_RS10750	COG2136	Putative SAM-dependent methyltransferase
NF53_RS10755	COG0018	arginyl-trna synthetase
NF53_RS10795	COG0017	Asparaginyl-tRNA synthetase
NF53_RS10800	COG0733	neurotransmitter:sodium symporter activity
NF53_RS10825	COG2610	gluconate transmembrane transporter activity
NF53_RS10835	COG1794	racemase activity, acting on amino acids and derivatives
NF53_RS10845	COG0456	acetyltransferase
NF53_RS10855	COG3655	Transcriptional regulator
NF53_RS10860	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NF53_RS10870	COG1131	(ABC) transporter
NF53_RS10875	COG4473	ABC transporter
NF53_RS10885	COG0546	phosphoglycolate phosphatase activity
NF53_RS10900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NF53_RS10915	COG0768	penicillin binding
NF53_RS10925	COG0204	Acyl-transferase
NF53_RS10930	COG1272	protein, Hemolysin III
NF53_RS10940	COG0805	protein transport
NF53_RS10950	COG1307	EDD domain protein, DegV family
NF53_RS10960	COG1999	signal sequence binding
NF53_RS10965	COG0071	Belongs to the small heat shock protein (HSP20) family
NF53_RS10970	COG0367	asparagine synthase
NF53_RS10985	COG0860	N-Acetylmuramoyl-L-alanine amidase
NF53_RS10990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NF53_RS10995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NF53_RS11015	COG1335	isochorismatase
NF53_RS11025	COG0668	transmembrane transport
NF53_RS11030	COG2203	Gaf domain
NF53_RS11030	COG4585	Histidine kinase
NF53_RS11035	COG2197	response regulator
NF53_RS11040	COG1737	Transcriptional regulator
NF53_RS11045	COG0384	phenazine biosynthesis protein PhzF
NF53_RS11050	COG1064	alcohol dehydrogenase
NF53_RS11065	COG1070	Carbohydrate kinase
NF53_RS11075	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NF53_RS11105	COG1125	glycine betaine transport
NF53_RS11105	COG0517	IMP dehydrogenase activity
NF53_RS11110	COG1174	glycine betaine transport
NF53_RS11145	COG1253	flavin adenine dinucleotide binding
NF53_RS11150	COG1012	belongs to the aldehyde dehydrogenase family
NF53_RS11155	COG5506	Protein of unknown function (DUF1694)
NF53_RS11170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NF53_RS11175	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NF53_RS11180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NF53_RS11185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF53_RS11190	COG0456	acetyltransferase
NF53_RS11195	COG3829	transcription factor binding
NF53_RS11200	COG1509	lysine 2,3-aminomutase activity
NF53_RS11235	COG0515	serine threonine protein kinase
NF53_RS11235	COG3064	Membrane
NF53_RS11235	COG4991	sh3 domain protein
NF53_RS11245	COG0671	phosphoesterase, PA-phosphatase related
NF53_RS11250	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NF53_RS11255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF53_RS11320	COG0300	oxidoreductase activity
NF53_RS11340	COG4499	WXG100 protein secretion system (Wss), protein YukC
NF53_RS11340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF53_RS11350	COG2814	Major facilitator Superfamily
NF53_RS11355	COG4841	protein insertion into membrane
NF53_RS11360	COG0372	Belongs to the citrate synthase family
NF53_RS11365	COG2079	MmgE PrpD family protein
NF53_RS11370	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NF53_RS11375	COG1960	acyl-CoA dehydrogenase activity
NF53_RS11380	COG2084	Dehydrogenase
NF53_RS11390	COG1280	lysine exporter protein (LysE YggA)
NF53_RS11395	COG1024	Enoyl-CoA hydratase
NF53_RS11410	COG0420	3'-5' exonuclease activity
NF53_RS11415	COG0419	ATPase involved in DNA repair
NF53_RS11440	COG2223	nitrite transmembrane transporter activity
NF53_RS11445	COG1028	Short-chain dehydrogenase reductase Sdr
NF53_RS11450	COG1169	isochorismate synthase
NF53_RS11455	COG1021	2,3-dihydroxybenzoate-AMP ligase
NF53_RS11460	COG3433	isochorismatase activity
NF53_RS11460	COG1535	isochorismatase
NF53_RS11465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF53_RS11470	COG3251	PFAM MbtH domain protein
NF53_RS11475	COG2814	Major facilitator Superfamily
NF53_RS11490	COG0776	regulation of translation
NF53_RS11500	COG2318	DinB family
NF53_RS11510	COG1115	amino acid carrier protein
NF53_RS11535	COG1187	pseudouridine synthase activity
NF53_RS11540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NF53_RS11545	COG1136	(ABC) transporter
NF53_RS11555	COG2814	Major facilitator Superfamily
NF53_RS11570	COG0028	Belongs to the TPP enzyme family
NF53_RS11610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NF53_RS11625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF53_RS11660	COG1247	-acetyltransferase
NF53_RS11685	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NF53_RS11695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS11725	COG0583	DNA-binding transcription factor activity
NF53_RS11730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NF53_RS11745	COG0583	DNA-binding transcription factor activity
NF53_RS11750	COG2258	MOSC domain
NF53_RS11765	COG1132	(ABC) transporter
NF53_RS11770	COG1132	(ABC) transporter
NF53_RS11825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NF53_RS11830	COG1595	DNA-templated transcription, initiation
NF53_RS11855	COG1649	PFAM Uncharacterised BCR, COG1649
NF53_RS11880	COG2971	BadF BadG BcrA BcrD
NF53_RS11900	COG1846	Transcriptional regulator
NF53_RS11995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NF53_RS11995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NF53_RS12075	COG2002	toxin-antitoxin pair type II binding
NF53_RS12110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NF53_RS12230	COG1388	LysM domain
NF53_RS12230	COG3409	Peptidoglycan-binding domain 1 protein
NF53_RS12230	COG5632	N-Acetylmuramoyl-L-alanine amidase
NF53_RS12295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF53_RS12310	COG1309	transcriptional regulator
NF53_RS12360	COG0582	viral genome integration into host DNA
NF53_RS12370	COG2323	membrane
NF53_RS12410	COG0500	methyltransferase
NF53_RS12410	COG3615	Tellurite resistance protein tehB
NF53_RS12420	COG2226	methyltransferase
NF53_RS12425	COG3961	Belongs to the TPP enzyme family
NF53_RS12430	COG1846	Transcriptional regulator
NF53_RS12460	COG2195	Cleaves the N-terminal amino acid of tripeptides
NF53_RS12485	COG2002	toxin-antitoxin pair type II binding
NF53_RS12495	COG0730	response to heat
NF53_RS12500	COG0110	maltose O-acetyltransferase activity
NF53_RS12505	COG1686	Belongs to the peptidase S11 family
NF53_RS12515	COG2814	Major facilitator Superfamily
NF53_RS12555	COG2312	Erythromycin esterase
NF53_RS12560	COG0741	lytic transglycosylase activity
NF53_RS12565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS12605	COG1760	l-serine dehydratase
NF53_RS12610	COG1760	l-serine dehydratase
NF53_RS12615	COG0814	amino acid
NF53_RS12635	COG1533	DNA photolyase activity
NF53_RS12650	COG0772	Belongs to the SEDS family
NF53_RS12655	COG2239	Acts as a magnesium transporter
NF53_RS12665	COG0768	penicillin binding
NF53_RS12670	COG1595	DNA-templated transcription, initiation
NF53_RS12680	COG0768	penicillin binding
NF53_RS12685	COG0768	penicillin binding
NF53_RS12695	COG1408	metallophosphoesterase
NF53_RS12705	COG1131	(ABC) transporter
NF53_RS12715	COG1309	transcriptional regulator
NF53_RS12730	COG1960	acyl-CoA dehydrogenase activity
NF53_RS12735	COG0439	Biotin carboxylase
NF53_RS12740	COG0511	ligase activity, forming carbon-carbon bonds
NF53_RS12745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NF53_RS12750	COG1024	Enoyl-CoA hydratase
NF53_RS12755	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NF53_RS12760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NF53_RS12780	COG0572	uridine kinase
NF53_RS12800	COG1686	Belongs to the peptidase S11 family
NF53_RS12825	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NF53_RS12840	COG3227	Zinc metalloprotease (Elastase)
NF53_RS12845	COG2207	Transcriptional regulator
NF53_RS12875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NF53_RS12900	COG2814	Major facilitator Superfamily
NF53_RS12905	COG1733	regulation of RNA biosynthetic process
NF53_RS12945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF53_RS12950	COG2368	4-hydroxyphenylacetate
NF53_RS12970	COG2323	membrane
NF53_RS12975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NF53_RS12985	COG3386	PFAM SMP-30 Gluconolaconase
NF53_RS13000	COG3773	Cell wall hydrolase
NF53_RS13010	COG0745	RESPONSE REGULATOR receiver
NF53_RS13015	COG2205	protein histidine kinase activity
NF53_RS13020	COG0488	(ABC) transporter
NF53_RS13030	COG1136	(ABC) transporter
NF53_RS13035	COG0577	efflux transmembrane transporter activity
NF53_RS13055	COG0460	homoserine dehydrogenase
NF53_RS13060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF53_RS13070	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NF53_RS13135	COG2124	cytochrome p450
NF53_RS13170	COG0561	phosphatase activity
NF53_RS13175	COG5002	protein histidine kinase activity
NF53_RS13180	COG0768	penicillin binding
NF53_RS13190	COG1819	glycosyl
NF53_RS13195	COG1794	racemase activity, acting on amino acids and derivatives
NF53_RS13215	COG2205	protein histidine kinase activity
NF53_RS13250	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NF53_RS13260	COG0745	RESPONSE REGULATOR receiver
NF53_RS13265	COG5002	protein histidine kinase activity
NF53_RS13270	COG0604	alcohol dehydrogenase
NF53_RS13275	COG0671	phosphoesterase, PA-phosphatase related
NF53_RS13280	COG0768	penicillin binding
NF53_RS13320	COG2814	Major facilitator Superfamily
NF53_RS13325	COG2814	Major facilitator Superfamily
NF53_RS13340	COG0584	glycerophosphoryl diester phosphodiesterase
NF53_RS13360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF53_RS13365	COG0697	spore germination
NF53_RS13400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NF53_RS13410	COG2223	nitrite transmembrane transporter activity
NF53_RS13425	COG0592	DNA-directed DNA polymerase activity
NF53_RS13450	COG3878	Protein conserved in bacteria
NF53_RS13470	COG4667	esterase of the alpha-beta hydrolase superfamily
NF53_RS13510	COG0322	excinuclease ABC activity
NF53_RS13550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NF53_RS13575	COG1011	Hydrolase
NF53_RS13580	COG0745	RESPONSE REGULATOR receiver
NF53_RS13585	COG5002	protein histidine kinase activity
NF53_RS13600	COG1136	(ABC) transporter
NF53_RS13605	COG0577	efflux transmembrane transporter activity
NF53_RS13610	COG1073	alpha beta
NF53_RS13615	COG0657	acetylesterase activity
NF53_RS13620	COG0076	glutamate decarboxylase activity
NF53_RS13635	COG1523	belongs to the glycosyl hydrolase 13 family
NF53_RS13640	COG3227	Zinc metalloprotease (Elastase)
NF53_RS13645	COG0737	Belongs to the 5'-nucleotidase family
NF53_RS13660	COG0201	protein transport
NF53_RS13665	COG0697	spore germination
NF53_RS13670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF53_RS13710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS13725	COG2959	enzyme of heme biosynthesis
NF53_RS13765	COG1309	transcriptional regulator
NF53_RS13795	COG3284	Transcriptional regulator
NF53_RS13815	COG1349	DNA-binding transcription factor activity
NF53_RS13830	COG1959	2 iron, 2 sulfur cluster binding
NF53_RS13845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NF53_RS13850	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF53_RS13855	COG0022	dehydrogenase e1 component
NF53_RS13860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NF53_RS13870	COG1028	Short-chain dehydrogenase reductase Sdr
NF53_RS13875	COG0456	acetyltransferase
NF53_RS13875	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NF53_RS13910	COG4176	ABC-type proline glycine betaine transport system permease component
NF53_RS13915	COG4175	Glycine betaine
NF53_RS13915	COG0517	IMP dehydrogenase activity
NF53_RS13945	COG2153	protein acetylation
NF53_RS13950	COG3397	chitin binding
NF53_RS13955	COG1819	glycosyl
NF53_RS13975	COG2205	protein histidine kinase activity
NF53_RS13980	COG2226	methyltransferase
NF53_RS13985	COG2315	Protein conserved in bacteria
NF53_RS14030	COG3973	AAA domain
NF53_RS14045	COG0514	ATP-dependent DNA helicase (RecQ)
NF53_RS14075	COG4637	Psort location Cytoplasmic, score
NF53_RS14090	COG3397	chitin binding
NF53_RS14105	COG1162	GTPase activity
NF53_RS14110	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NF53_RS14115	COG1115	amino acid carrier protein
NF53_RS14120	COG1012	belongs to the aldehyde dehydrogenase family
NF53_RS14125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NF53_RS14135	COG3938	Belongs to the proline racemase family
NF53_RS14140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NF53_RS14185	COG0586	Pfam SNARE associated Golgi protein
NF53_RS14195	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NF53_RS14205	COG4166	transmembrane transport
NF53_RS14215	COG4948	Mandelate Racemase Muconate Lactonizing
NF53_RS14230	COG0667	Aldo Keto reductase
NF53_RS14275	COG5002	protein histidine kinase activity
NF53_RS14275	COG3850	Histidine kinase
NF53_RS14280	COG0745	RESPONSE REGULATOR receiver
NF53_RS14320	COG1164	Oligoendopeptidase f
NF53_RS14325	COG1307	EDD domain protein, DegV family
NF53_RS14365	COG2814	Major facilitator Superfamily
NF53_RS14375	COG1664	Polymer-forming cytoskeletal
NF53_RS14380	COG0789	Transcriptional regulator
NF53_RS14385	COG4533	DNA binding
NF53_RS14390	COG2814	Major facilitator Superfamily
NF53_RS14390	COG0477	Major facilitator Superfamily
NF53_RS14410	COG2261	transglycosylase associated protein
NF53_RS14460	COG0436	Aminotransferase
NF53_RS14465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NF53_RS14475	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NF53_RS14520	COG0628	permease
NF53_RS14535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF53_RS14540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NF53_RS14545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NF53_RS14575	COG2746	aminoglycoside 3-N-acetyltransferase activity
NF53_RS14595	COG0697	spore germination
NF53_RS14615	COG4912	Dna alkylation repair
NF53_RS14620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NF53_RS14625	COG0346	lactoylglutathione lyase activity
NF53_RS14635	COG0861	Integral membrane protein TerC family
NF53_RS14640	COG1368	sulfuric ester hydrolase activity
NF53_RS14645	COG0488	(ABC) transporter
NF53_RS14650	COG2409	Drug exporters of the RND superfamily
NF53_RS14650	COG1033	growth of symbiont in host cell
NF53_RS14655	COG1309	transcriptional regulator
NF53_RS14670	COG0287	Prephenate dehydrogenase
NF53_RS14685	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NF53_RS14685	COG1605	Chorismate mutase
NF53_RS14730	COG3584	3D domain protein
NF53_RS14730	COG1388	LysM domain
NF53_RS14740	COG0346	lactoylglutathione lyase activity
NF53_RS14770	COG1879	ABC-type sugar transport system periplasmic component
NF53_RS14775	COG1172	Belongs to the binding-protein-dependent transport system permease family
NF53_RS14780	COG1172	Belongs to the binding-protein-dependent transport system permease family
NF53_RS14790	COG2390	Transcriptional regulator
NF53_RS14795	COG1070	Carbohydrate kinase
NF53_RS14810	COG2329	Antibiotic biosynthesis monooxygenase
NF53_RS14830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NF53_RS14845	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NF53_RS14850	COG4187	Peptidase family M20/M25/M40
NF53_RS14855	COG1414	Transcriptional regulator
NF53_RS14860	COG0833	amino acid
NF53_RS14870	COG3239	Fatty acid desaturase
NF53_RS14880	COG2720	vancomycin resistance protein
NF53_RS14885	COG1785	Belongs to the alkaline phosphatase family
NF53_RS14895	COG3655	Transcriptional regulator
NF53_RS14920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS14925	COG0346	lactoylglutathione lyase activity
NF53_RS14945	COG0714	Associated with various cellular activities
NF53_RS14970	COG0463	Glycosyl transferase, family 2
NF53_RS15005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NF53_RS15010	COG0753	catalase activity
NF53_RS15050	COG0714	Associated with various cellular activities
NF53_RS15090	COG0778	Nitroreductase
NF53_RS15095	COG1846	Transcriptional regulator
NF53_RS15115	COG4884	unkown
NF53_RS15115	COG3831	ATPase activity
NF53_RS15130	COG1136	(ABC) transporter
NF53_RS15130	COG0577	efflux transmembrane transporter activity
NF53_RS15160	COG0037	tRNA processing
NF53_RS15160	COG0590	tRNA wobble adenosine to inosine editing
NF53_RS15165	COG0456	acetyltransferase
NF53_RS15180	COG0697	spore germination
NF53_RS15185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF53_RS15200	COG0642	Histidine kinase
NF53_RS15205	COG0745	RESPONSE REGULATOR receiver
NF53_RS15210	COG0596	Alpha beta hydrolase
NF53_RS15245	COG0730	response to heat
NF53_RS15255	COG0833	amino acid
NF53_RS15265	COG4335	DNA alkylation repair
NF53_RS15305	COG0768	penicillin binding
NF53_RS15340	COG1984	allophanate hydrolase subunit 2
NF53_RS15345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NF53_RS15350	COG1414	Transcriptional regulator
NF53_RS15360	COG3142	Participates in the control of copper homeostasis
NF53_RS15365	COG0640	Transcriptional regulator
NF53_RS15375	COG1960	acyl-CoA dehydrogenase activity
NF53_RS15390	COG3314	Sporulation integral membrane protein YlbJ
NF53_RS15410	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NF53_RS15430	COG0574	Belongs to the PEP-utilizing enzyme family
NF53_RS15430	COG3848	Pyruvate phosphate dikinase
NF53_RS15440	COG0367	asparagine synthase
NF53_RS15445	COG0583	DNA-binding transcription factor activity
NF53_RS15480	COG1028	Short-chain dehydrogenase reductase Sdr
NF53_RS15485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF53_RS15505	COG1063	alcohol dehydrogenase
NF53_RS15515	COG1027	Aspartate ammonia-lyase
NF53_RS15520	COG0252	asparaginase activity
NF53_RS15525	COG1396	sequence-specific DNA binding
NF53_RS15550	COG5002	protein histidine kinase activity
NF53_RS15555	COG0745	RESPONSE REGULATOR receiver
NF53_RS15565	COG5002	protein histidine kinase activity
NF53_RS15590	COG2207	Transcriptional regulator
NF53_RS15605	COG0322	excinuclease ABC activity
NF53_RS15610	COG0531	amino acid
NF53_RS15615	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NF53_RS15625	COG0531	amino acid
NF53_RS15630	COG0697	spore germination
NF53_RS15635	COG0784	Response regulator, receiver
NF53_RS15640	COG4191	Histidine kinase
NF53_RS15650	COG1115	amino acid carrier protein
NF53_RS15675	COG0737	Belongs to the 5'-nucleotidase family
NF53_RS15680	COG2267	carboxylic ester hydrolase activity
NF53_RS15685	COG1335	isochorismatase
NF53_RS15705	COG0583	DNA-binding transcription factor activity
NF53_RS15715	COG2814	Major facilitator Superfamily
NF53_RS15720	COG1309	transcriptional regulator
NF53_RS15745	COG0598	Magnesium transport protein CorA
NF53_RS15765	COG1073	alpha beta
NF53_RS15785	COG0415	Belongs to the DNA photolyase family
NF53_RS15820	COG2814	Major facilitator Superfamily
NF53_RS15830	COG0657	acetylesterase activity
NF53_RS15835	COG0288	reversible hydration of carbon dioxide
NF53_RS15845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NF53_RS15850	COG5609	conserved protein (DUF2294)
NF53_RS15855	COG2814	Major facilitator Superfamily
NF53_RS15885	COG5002	protein histidine kinase activity
NF53_RS15890	COG0745	RESPONSE REGULATOR receiver
NF53_RS15915	COG1329	Transcriptional regulator
NF53_RS15930	COG2962	Rard protein
NF53_RS15935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NF53_RS15945	COG1575	Belongs to the MenA family. Type 1 subfamily
NF53_RS15955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS15965	COG0798	PFAM Bile acid sodium symporter
NF53_RS15970	COG0346	lactoylglutathione lyase activity
NF53_RS15975	COG0640	Transcriptional regulator
NF53_RS15985	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NF53_RS16000	COG3320	Male sterility
NF53_RS16000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF53_RS16005	COG1309	transcriptional regulator
NF53_RS16020	COG0346	lactoylglutathione lyase activity
NF53_RS16100	COG2814	Major facilitator Superfamily
NF53_RS16120	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NF53_RS16130	COG1690	Belongs to the RtcB family
NF53_RS16140	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NF53_RS16160	COG0577	efflux transmembrane transporter activity
NF53_RS16175	COG5002	protein histidine kinase activity
NF53_RS16175	COG3850	Histidine kinase
NF53_RS16185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF53_RS16210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NF53_RS16250	COG3409	Peptidoglycan-binding domain 1 protein
NF53_RS16250	COG5632	N-Acetylmuramoyl-L-alanine amidase
NF53_RS16400	COG1876	peptidase activity
NF53_RS16405	COG2843	Capsule synthesis protein
NF53_RS16415	COG0477	Major facilitator Superfamily
NF53_RS16430	COG1846	Transcriptional regulator
NF53_RS16435	COG2814	Major facilitator Superfamily
NF53_RS16445	COG2031	fatty acid transporter
NF53_RS16510	COG1288	antiporter activity
NF53_RS16515	COG2356	endonuclease I
NF53_RS16535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NF53_RS16555	COG1733	regulation of RNA biosynthetic process
NF53_RS16560	COG0778	Nitroreductase
NF53_RS16590	COG1028	Short-chain dehydrogenase reductase Sdr
NF53_RS16600	COG1131	(ABC) transporter
NF53_RS16625	COG1011	Hydrolase
NF53_RS16630	COG2365	Tyrosine phosphatase family
NF53_RS16660	COG0628	permease
NF53_RS16690	COG0500	methyltransferase
NF53_RS16700	COG0477	Major facilitator Superfamily
NF53_RS16730	COG1253	flavin adenine dinucleotide binding
NF53_RS16735	COG0789	Transcriptional regulator
NF53_RS16745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NF53_RS16775	COG0697	spore germination
NF53_RS16785	COG1357	PFAM Pentapeptide repeats (8 copies)
NF53_RS16790	COG3813	Protein conserved in bacteria
NF53_RS16795	COG2706	6-phosphogluconolactonase activity
NF53_RS16800	COG1070	Carbohydrate kinase
NF53_RS16810	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NF53_RS16815	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NF53_RS16820	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NF53_RS16825	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NF53_RS16850	COG0840	transmembrane signaling receptor activity
NF53_RS16860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NF53_RS16860	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NF53_RS16865	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NF53_RS16865	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NF53_RS16870	COG1733	regulation of RNA biosynthetic process
NF53_RS16895	COG2824	Alkylphosphonate utilization operon protein PhnA
NF53_RS16900	COG0659	secondary active sulfate transmembrane transporter activity
NF53_RS16915	COG0814	amino acid
NF53_RS16940	COG2188	Transcriptional regulator
NF53_RS16945	COG0673	inositol 2-dehydrogenase activity
NF53_RS16965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF53_RS16985	COG0384	phenazine biosynthesis protein PhzF
NF53_RS16990	COG0318	PFAM AMP-dependent synthetase and ligase
NF53_RS16995	COG2249	NAD(P)H dehydrogenase (quinone) activity
NF53_RS17000	COG1733	regulation of RNA biosynthetic process
NF53_RS17025	COG1191	sigma factor activity
NF53_RS17045	COG1280	lysine exporter protein (LysE YggA)
NF53_RS17085	COG1151	hydroxylamine reductase activity
NF53_RS17095	COG3409	Peptidoglycan-binding domain 1 protein
NF53_RS17095	COG3757	hydrolase, family 25
NF53_RS17125	COG2072	flavoprotein involved in K transport
NF53_RS17160	COG1113	amino acid transport
NF53_RS17165	COG2814	Major facilitator Superfamily
NF53_RS17195	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NF53_RS17200	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NF53_RS17210	COG1247	-acetyltransferase
NF53_RS17215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NF53_RS17220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF53_RS17225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF53_RS17230	COG3739	integral membrane protein
NF53_RS17260	COG0583	DNA-binding transcription factor activity
NF53_RS17290	COG1193	negative regulation of DNA recombination
NF53_RS17305	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NF53_RS17310	COG1164	Oligoendopeptidase f
NF53_RS17315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NF53_RS17340	COG0584	glycerophosphoryl diester phosphodiesterase
NF53_RS17355	COG0640	Transcriptional regulator
NF53_RS17360	COG0604	alcohol dehydrogenase
NF53_RS17370	COG0457	Tetratricopeptide repeat
NF53_RS17380	COG2808	Putative FMN-binding domain
NF53_RS17385	COG0456	acetyltransferase
NF53_RS17385	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NF53_RS17395	COG0277	FAD linked oxidase domain protein
NF53_RS17420	COG1183	phosphatidylcholine synthase activity
NF53_RS17430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NF53_RS17430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF53_RS17435	COG1252	NADH dehydrogenase
NF53_RS17445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NF53_RS17455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF53_RS17465	COG0457	Tetratricopeptide repeat
NF53_RS17745	COG1404	Belongs to the peptidase S8 family
NF53_RS17790	COG5002	protein histidine kinase activity
NF53_RS17795	COG5002	protein histidine kinase activity
NF53_RS17805	COG3584	3D domain protein
NF53_RS17805	COG1388	LysM domain
NF53_RS17855	COG1388	LysM domain
NF53_RS17855	COG3409	Peptidoglycan-binding domain 1 protein
NF53_RS17855	COG5632	N-Acetylmuramoyl-L-alanine amidase
NF53_RS17875	COG1393	Belongs to the ArsC family
NF53_RS17915	COG0488	(ABC) transporter
NF53_RS17940	COG3852	Histidine kinase
NF53_RS17950	COG1285	pathogenesis
NF53_RS17960	COG2514	catechol 2,3-dioxygenase activity
NF53_RS17965	COG2720	vancomycin resistance protein
NF53_RS18005	COG0716	FMN binding
NF53_RS18015	COG0494	nUDIX hydrolase
NF53_RS18035	COG1028	Short-chain dehydrogenase reductase Sdr
NF53_RS18045	COG0165	Argininosuccinate lyase
NF53_RS18060	COG4145	pantothenate transmembrane transporter activity
NF53_RS18070	COG1012	belongs to the aldehyde dehydrogenase family
NF53_RS18075	COG1028	Short-chain dehydrogenase reductase Sdr
NF53_RS18085	COG1657	PFAM Prenyltransferase squalene oxidase
NF53_RS18090	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NF53_RS18095	COG2962	Rard protein
NF53_RS18100	COG3326	Membrane
NF53_RS18115	COG0489	protein tyrosine kinase activity
NF53_RS18125	COG0314	molybdopterin synthase activity
NF53_RS18130	COG0303	'Molybdopterin
NF53_RS18135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NF53_RS18140	COG2116	formate transmembrane transporter activity
NF53_RS18150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NF53_RS18155	COG5609	conserved protein (DUF2294)
NF53_RS18160	COG2427	Protein of unknown function (DUF1641)
NF53_RS18165	COG3383	formate dehydrogenase (NAD+) activity
NF53_RS18175	COG0697	spore germination
NF53_RS18190	COG0531	amino acid
NF53_RS18225	COG2226	methyltransferase
NF53_RS18230	COG4166	transmembrane transport
NF53_RS18235	COG4166	transmembrane transport
NF53_RS18240	COG4166	transmembrane transport
NF53_RS18245	COG1316	TRANSCRIPTIONal
NF53_RS18255	COG1595	DNA-templated transcription, initiation
NF53_RS18265	COG1131	(ABC) transporter
NF53_RS18275	COG0673	inositol 2-dehydrogenase activity
NF53_RS18280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NF53_RS18285	COG0187	DNA topoisomerase II activity
NF53_RS18295	COG1832	CoA-binding protein
NF53_RS18300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NF53_RS18305	COG0745	RESPONSE REGULATOR receiver
NF53_RS18325	COG4841	protein insertion into membrane
NF53_RS18330	COG0824	Thioesterase
NF53_RS18360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF53_RS18375	COG1132	(ABC) transporter
NF53_RS18380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NF53_RS18410	COG2211	Major facilitator Superfamily
NF53_RS18420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NF53_RS18435	COG0183	Belongs to the thiolase family
NF53_RS18440	COG0318	PFAM AMP-dependent synthetase and ligase
NF53_RS18445	COG1268	BioY protein
NF53_RS18450	COG0318	PFAM AMP-dependent synthetase and ligase
NF53_RS18455	COG1396	sequence-specific DNA binding
NF53_RS18505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF53_RS18515	COG5002	protein histidine kinase activity
NF53_RS18520	COG0400	carboxylic ester hydrolase activity
NF53_RS18525	COG0346	lactoylglutathione lyase activity
NF53_RS18530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NF53_RS18540	COG0069	glutamate synthase activity
NF53_RS18545	COG1902	pentaerythritol trinitrate reductase activity
NF53_RS18550	COG1329	Transcriptional regulator
NF53_RS18555	COG0010	Belongs to the arginase family
NF53_RS18580	COG2226	methyltransferase
NF53_RS18585	COG0693	protein deglycase activity
NF53_RS18610	COG4846	Membrane protein involved in cytochrome C biogenesis
NF53_RS18615	COG0785	Cytochrome C biogenesis protein
NF53_RS18625	COG1473	amidohydrolase
NF53_RS18635	COG1131	(ABC) transporter
NF53_RS18650	COG0583	DNA-binding transcription factor activity
NF53_RS18660	COG1346	cytolysis
NF53_RS18675	COG0730	response to heat
NF53_RS18700	COG1132	(ABC) transporter
NF53_RS18705	COG1132	(ABC) transporter
NF53_RS18730	COG3639	organic phosphonate transmembrane transporter activity
NF53_RS18740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NF53_RS18745	COG0737	Belongs to the 5'-nucleotidase family
NF53_RS18755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NF53_RS18775	COG1695	Transcriptional regulator
NF53_RS18780	COG0174	glutamine synthetase
NF53_RS18785	COG0789	Transcriptional regulator
NF53_RS18790	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NF53_RS18795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NF53_RS18800	COG2860	membrane
NF53_RS18810	COG0464	growth
NF53_RS18840	COG3584	3D domain protein
NF53_RS18840	COG1388	LysM domain
NF53_RS18845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NF53_RS18845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NF53_RS18845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF53_RS18850	COG1105	Belongs to the carbohydrate kinase PfkB family
NF53_RS18855	COG1349	DNA-binding transcription factor activity
NF53_RS18860	COG1979	alcohol dehydrogenase
NF53_RS18865	COG2322	membrane
NF53_RS18880	COG1113	amino acid transport
NF53_RS18890	COG1408	metallophosphoesterase
NF53_RS18895	COG2116	formate transmembrane transporter activity
NF53_RS18910	COG2217	Heavy metal translocating P-type atpase
NF53_RS18915	COG2608	mercury ion transmembrane transporter activity
NF53_RS18920	COG1937	Protein conserved in bacteria
NF53_RS18925	COG1464	Belongs to the NlpA lipoprotein family
NF53_RS18935	COG2819	hydrolase of the alpha beta superfamily
NF53_RS18940	COG1120	ATPase activity
NF53_RS18945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF53_RS18950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF53_RS18955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NF53_RS18960	COG2169	Transcriptional regulator
NF53_RS18965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NF53_RS18970	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NF53_RS18980	COG2364	Membrane
NF53_RS18995	COG2267	carboxylic ester hydrolase activity
NF53_RS19000	COG5001	Diguanylate cyclase
NF53_RS19000	COG3300	MHYT domain
NF53_RS19020	COG1086	Polysaccharide biosynthesis protein
NF53_RS19040	COG1346	cytolysis
NF53_RS19050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF53_RS19060	COG2188	Transcriptional regulator
NF53_RS19065	COG2723	6-phospho-beta-galactosidase activity
NF53_RS19075	COG1404	Belongs to the peptidase S8 family
NF53_RS19080	COG3773	Cell wall hydrolase
NF53_RS19090	COG1368	sulfuric ester hydrolase activity
NF53_RS19095	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NF53_RS19120	COG4550	Control of competence regulator ComK, YlbF/YmcA
NF53_RS19130	COG1013	pyruvate-flavodoxin oxidoreductase activity
NF53_RS19135	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NF53_RS19135	COG0674	pyruvate-flavodoxin oxidoreductase activity
NF53_RS19145	COG2359	stage V sporulation protein S
NF53_RS19150	COG1692	metallophosphoesterase
NF53_RS19175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NF53_RS19180	COG1426	Protein conserved in bacteria
NF53_RS19195	COG0300	oxidoreductase activity
NF53_RS19200	COG0612	Peptidase, M16
NF53_RS19205	COG0612	Peptidase, M16
NF53_RS19210	COG1079	Belongs to the binding-protein-dependent transport system permease family
NF53_RS19215	COG4603	Belongs to the binding-protein-dependent transport system permease family
NF53_RS19220	COG3845	ABC transporter
NF53_RS19225	COG1744	ABC transporter substrate-binding protein PnrA-like
NF53_RS19230	COG2188	Transcriptional regulator
NF53_RS19245	COG0740	serine-type endopeptidase activity
NF53_RS19250	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NF53_RS19265	COG0527	aspartate kinase activity
NF53_RS19270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NF53_RS19275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NF53_RS19290	COG1388	LysM domain
NF53_RS19290	COG3409	Peptidoglycan-binding domain 1 protein
NF53_RS19290	COG5632	N-Acetylmuramoyl-L-alanine amidase
NF53_RS19295	COG4824	toxin secretion phage lysis holin
NF53_RS19405	COG1278	Cold shock
NF53_RS19410	COG0582	viral genome integration into host DNA
NF53_RS19450	COG0305	Participates in initiation and elongation during chromosome replication
NF53_RS19510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NF53_RS19515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NF53_RS19520	COG1873	PFAM PRC-barrel domain
NF53_RS19525	COG0612	Peptidase, M16
NF53_RS19530	COG0726	polysaccharide deacetylase
NF53_RS19545	COG0196	riboflavin kinase activity
NF53_RS19555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NF53_RS19560	COG1550	Protein conserved in bacteria
NF53_RS19570	COG1358	cellular component organization or biogenesis
NF53_RS19575	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NF53_RS19580	COG0195	Participates in both transcription termination and antitermination
NF53_RS19600	COG0750	zinc metalloprotease
NF53_RS19610	COG4589	Belongs to the CDS family
NF53_RS19655	COG4974	Belongs to the 'phage' integrase family
NF53_RS19665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NF53_RS19670	COG0758	DNA mediated transformation
NF53_RS19675	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NF53_RS19715	COG1837	Belongs to the UPF0109 family
NF53_RS19725	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NF53_RS19735	COG0552	protein localization to endoplasmic reticulum
NF53_RS19740	COG1196	nuclear chromosome segregation
NF53_RS19750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF53_RS19755	COG1028	Short-chain dehydrogenase reductase Sdr
NF53_RS19760	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NF53_RS19775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NF53_RS19780	COG1461	Dihydroxyacetone kinase
NF53_RS19785	COG1302	Protein conserved in bacteria
NF53_RS19800	COG1564	THIamine pyrophosphokinase
NF53_RS19805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NF53_RS19815	COG0515	serine threonine protein kinase
NF53_RS19815	COG2815	serine threonine protein kinase
NF53_RS19820	COG0631	protein serine/threonine phosphatase activity
NF53_RS19830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NF53_RS19830	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NF53_RS19845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NF53_RS19850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NF53_RS19870	COG1561	YicC-like family, N-terminal region
NF53_RS19875	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NF53_RS19885	COG0006	proline dipeptidase activity
NF53_RS19895	COG3069	C4-dicarboxylate transmembrane transporter activity
NF53_RS19905	COG0546	phosphoglycolate phosphatase activity
NF53_RS19960	COG0564	pseudouridine synthase activity
NF53_RS19980	COG3599	regulation of cell shape
NF53_RS19985	COG2302	S4 RNA-binding domain
NF53_RS19990	COG0762	integral membrane protein
NF53_RS20000	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NF53_RS20010	COG1873	PFAM PRC-barrel domain
NF53_RS20015	COG1191	sigma factor activity
NF53_RS20020	COG1191	sigma factor activity
NF53_RS20030	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NF53_RS20035	COG0849	cell division
NF53_RS20055	COG0772	Belongs to the SEDS family
NF53_RS20075	COG0768	penicillin binding
NF53_RS20080	COG0768	penicillin binding
NF53_RS20100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NF53_RS20115	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NF53_RS20120	COG1399	metal-binding, possibly nucleic acid-binding protein
NF53_RS20130	COG3480	Lon protease (S16) C-terminal proteolytic domain
NF53_RS20135	COG1752	Esterase of the alpha-beta hydrolase superfamily
NF53_RS20140	COG3314	Sporulation integral membrane protein YlbJ
NF53_RS20150	COG0742	ribosomal rna small subunit methyltransferase
NF53_RS20165	COG3679	Belongs to the UPF0342 family
NF53_RS20170	COG0406	alpha-ribazole phosphatase activity
NF53_RS20185	COG2340	Cysteine-rich secretory protein family
NF53_RS20200	COG3336	cytochrome c oxidase
NF53_RS20235	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NF53_RS20240	COG0772	Belongs to the SEDS family
NF53_RS20250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NF53_RS20255	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NF53_RS20265	COG4896	Protein conserved in bacteria
NF53_RS20280	COG1217	gtp-binding protein TYPA
NF53_RS20290	COG0483	inositol monophosphate 1-phosphatase activity
NF53_RS20310	COG1982	Orn Lys Arg decarboxylase major
NF53_RS20360	COG0022	dehydrogenase e1 component
NF53_RS20365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NF53_RS20380	COG0561	phosphatase activity
NF53_RS20390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NF53_RS20395	COG0569	domain protein
NF53_RS20415	COG0583	DNA-binding transcription factor activity
NF53_RS20420	COG0517	IMP dehydrogenase activity
NF53_RS20430	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NF53_RS20440	COG4703	Protein of unknown function (DUF1797)
NF53_RS20455	COG2200	EAL domain
NF53_RS20460	COG1028	Short-chain dehydrogenase reductase Sdr
NF53_RS20465	COG1408	metallophosphoesterase
NF53_RS20510	COG2814	Major facilitator Superfamily
NF53_RS20535	COG3209	COG3209 Rhs family protein
NF53_RS20545	COG2205	protein histidine kinase activity
NF53_RS20555	COG0436	Aminotransferase
NF53_RS20560	COG1609	Transcriptional regulator
NF53_RS20565	COG3833	ABC-type maltose transport systems, permease component
NF53_RS20570	COG1175	transmembrane transport
NF53_RS20575	COG2182	Extracellular solute-binding protein
NF53_RS20585	COG0366	Alpha amylase catalytic
NF53_RS20590	COG3842	ATPase activity
NF53_RS20630	COG0183	Belongs to the thiolase family
NF53_RS20665	COG1695	Transcriptional regulator
NF53_RS20670	COG1028	Short-chain dehydrogenase reductase Sdr
NF53_RS20690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NF53_RS20695	COG0436	Aminotransferase
NF53_RS20730	COG2084	Dehydrogenase
NF53_RS20740	COG2199	diguanylate cyclase activity
NF53_RS20745	COG0778	Nitroreductase
NF53_RS20770	COG1263	PTS System
NF53_RS20770	COG2190	(PTS) system
NF53_RS20770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF53_RS20775	COG3711	transcriptional antiterminator
NF53_RS20785	COG2188	Transcriptional regulator
NF53_RS20795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NF53_RS20825	COG1547	Domain of unknown function (DUF309)
NF53_RS20830	COG0456	acetyltransferase
NF53_RS20835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NF53_RS20840	COG4086	secreted protein
NF53_RS20845	COG0561	phosphatase activity
NF53_RS20850	COG0697	spore germination
NF53_RS20865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NF53_RS20890	COG0733	neurotransmitter:sodium symporter activity
NF53_RS20910	COG1686	Belongs to the peptidase S11 family
NF53_RS20915	COG1725	Transcriptional regulator
NF53_RS20920	COG1131	(ABC) transporter
NF53_RS20935	COG1846	Transcriptional regulator
NF53_RS20950	COG0598	Magnesium transport protein CorA
NF53_RS20975	COG4974	Belongs to the 'phage' integrase family
NF53_RS20985	COG0735	belongs to the Fur family
NF53_RS20990	COG1300	Membrane
NF53_RS21010	COG0667	Aldo Keto reductase
NF53_RS21015	COG0656	L-ascorbic acid biosynthetic process
NF53_RS21020	COG0456	acetyltransferase
NF53_RS21020	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NF53_RS21030	COG1525	nuclease
NF53_RS21030	COG4085	toxin activity
NF53_RS21030	COG0737	Belongs to the 5'-nucleotidase family
NF53_RS21040	COG0596	Alpha beta hydrolase
NF53_RS21045	COG2056	Na+-H+ antiporter family
NF53_RS21050	COG1609	Transcriptional regulator
NF53_RS21055	COG0456	acetyltransferase
NF53_RS21060	COG1073	alpha beta
NF53_RS21075	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NF53_RS21075	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NF53_RS21080	COG0307	riboflavin synthase, alpha
NF53_RS21110	COG1073	alpha beta
NF53_RS21110	COG2226	methyltransferase
NF53_RS21125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NF53_RS21135	COG1757	Na H antiporter
NF53_RS21140	COG0737	Belongs to the 5'-nucleotidase family
NF53_RS21150	COG1522	sequence-specific DNA binding
NF53_RS21195	COG0300	oxidoreductase activity
NF53_RS21200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF53_RS21205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NF53_RS21210	COG1760	l-serine dehydratase
NF53_RS21215	COG1760	l-serine dehydratase
NF53_RS21245	COG2195	Cleaves the N-terminal amino acid of tripeptides
NF53_RS21250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS21265	COG1376	ErfK ybiS ycfS ynhG family protein
NF53_RS21270	COG4129	membrane
NF53_RS21275	COG1126	abc transporter atp-binding protein
NF53_RS21280	COG0765	amino acid transport
NF53_RS21285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NF53_RS21310	COG2323	membrane
NF53_RS21315	COG0772	Belongs to the SEDS family
NF53_RS21325	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF53_RS21330	COG0022	dehydrogenase e1 component
NF53_RS21335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NF53_RS21340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NF53_RS21355	COG0280	phosphate acetyltransferase
NF53_RS21365	COG3829	transcription factor binding
NF53_RS21365	COG3290	protein histidine kinase activity
NF53_RS21375	COG0584	glycerophosphoryl diester phosphodiesterase
NF53_RS21380	COG3093	addiction module antidote protein HigA
NF53_RS21400	COG0750	zinc metalloprotease
NF53_RS21405	COG0497	DNA recombination
NF53_RS21415	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NF53_RS21425	COG0142	geranyltranstransferase activity
NF53_RS21450	COG1302	Protein conserved in bacteria
NF53_RS21455	COG0439	Biotin carboxylase
NF53_RS21460	COG0511	ligase activity, forming carbon-carbon bonds
NF53_RS21505	COG3854	ATPases associated with a variety of cellular activities
NF53_RS21530	COG0006	proline dipeptidase activity
NF53_RS21545	COG3872	metal-dependent enzyme
NF53_RS21555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NF53_RS21585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NF53_RS21595	COG1609	Transcriptional regulator
NF53_RS21605	COG2076	Multidrug Resistance protein
NF53_RS21610	COG2076	Multidrug Resistance protein
NF53_RS21655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NF53_RS21720	COG1459	type II secretion system
NF53_RS21725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NF53_RS21780	COG0646	methionine synthase
NF53_RS21780	COG1410	methionine synthase
NF53_RS21785	COG0646	methionine synthase
NF53_RS21785	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NF53_RS21795	COG0626	cystathionine gamma-synthase activity
NF53_RS21800	COG0626	cystathionine gamma-synthase activity
NF53_RS21820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF53_RS21830	COG1940	carbohydrate kinase activity
NF53_RS21835	COG4483	Protein conserved in bacteria
NF53_RS21840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NF53_RS21845	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NF53_RS21850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NF53_RS21855	COG0704	Plays a role in the regulation of phosphate uptake
NF53_RS21865	COG0573	inorganic phosphate transmembrane transporter activity
NF53_RS21870	COG0573	inorganic phosphate transmembrane transporter activity
NF53_RS21880	COG0768	penicillin binding
NF53_RS21885	COG0477	Major facilitator Superfamily
NF53_RS21890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NF53_RS21900	COG5521	maltodextrose utilization protein MalA
NF53_RS21915	COG0735	belongs to the Fur family
NF53_RS21920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NF53_RS21925	COG1121	(ABC) transporter
NF53_RS21930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF53_RS21960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NF53_RS21965	COG2384	SAM-dependent methyltransferase
NF53_RS21975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NF53_RS21980	COG0358	DNA primase activity
NF53_RS21995	COG0517	IMP dehydrogenase activity
NF53_RS22010	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NF53_RS22015	COG0295	cytidine deaminase activity
NF53_RS22020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NF53_RS22030	COG1480	7TM receptor with intracellular HD hydrolase
NF53_RS22035	COG1702	phosphate starvation-inducible protein PhoH
NF53_RS22050	COG1610	YqeY-like protein
NF53_RS22055	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NF53_RS22060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NF53_RS22065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NF53_RS22095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NF53_RS22100	COG1733	regulation of RNA biosynthetic process
NF53_RS22125	COG1466	dna polymerase III delta subunit
NF53_RS22135	COG0658	competence protein
NF53_RS22135	COG2333	competence protein COMEC
NF53_RS22140	COG2131	deaminase
NF53_RS22145	COG1555	photosystem II stabilization
NF53_RS22145	COG1596	polysaccharide export
NF53_RS22150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NF53_RS22155	COG2226	methyltransferase
NF53_RS22160	COG0799	negative regulation of ribosome biogenesis
NF53_RS22165	COG1713	HD superfamily hydrolase involved in NAD metabolism
NF53_RS22175	COG1534	Rna-binding protein
NF53_RS22185	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NF53_RS22190	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NF53_RS22215	COG1595	DNA-templated transcription, initiation
NF53_RS22225	COG0778	Nitroreductase
NF53_RS22230	COG2357	RelA SpoT domain protein
NF53_RS22240	COG1785	Belongs to the alkaline phosphatase family
NF53_RS22250	COG2267	carboxylic ester hydrolase activity
NF53_RS22290	COG1404	Belongs to the peptidase S8 family
NF53_RS22295	COG3186	Phenylalanine-4-hydroxylase
NF53_RS22305	COG2514	catechol 2,3-dioxygenase activity
NF53_RS22310	COG2259	Doxx family
NF53_RS22350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NF53_RS22360	COG1454	alcohol dehydrogenase
NF53_RS22360	COG1012	belongs to the aldehyde dehydrogenase family
NF53_RS22365	COG0626	cystathionine gamma-synthase activity
NF53_RS22370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NF53_RS22395	COG0768	penicillin binding
NF53_RS22415	COG0826	peptidase U32
NF53_RS22420	COG0826	peptidase U32
NF53_RS22425	COG4122	O-methyltransferase activity
NF53_RS22430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NF53_RS22460	COG0628	permease
NF53_RS22480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NF53_RS22495	COG1104	cysteine desulfurase activity
NF53_RS22500	COG1959	2 iron, 2 sulfur cluster binding
NF53_RS22505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NF53_RS22520	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NF53_RS22545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NF53_RS22555	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NF53_RS22555	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NF53_RS22560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NF53_RS22565	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NF53_RS22565	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NF53_RS22575	COG2244	polysaccharide biosynthetic process
NF53_RS22580	COG2323	membrane
NF53_RS22590	COG1862	Preprotein translocase
NF53_RS22620	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NF53_RS22650	COG0157	Belongs to the NadC ModD family
NF53_RS22655	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NF53_RS22660	COG1104	cysteine desulfurase activity
NF53_RS22665	COG1827	regulation of RNA biosynthetic process
NF53_RS22670	COG2258	MOSC domain
NF53_RS22680	COG0077	Prephenate dehydratase
NF53_RS22685	COG0577	efflux transmembrane transporter activity
NF53_RS22690	COG0577	efflux transmembrane transporter activity
NF53_RS22695	COG1136	(ABC) transporter
NF53_RS22700	COG5002	protein histidine kinase activity
NF53_RS22705	COG0745	RESPONSE REGULATOR receiver
NF53_RS22715	COG3290	protein histidine kinase activity
NF53_RS22725	COG2868	ribosomal protein
NF53_RS22735	COG1530	ribonuclease E activity
NF53_RS22740	COG1994	Peptidase M50
NF53_RS22745	COG0739	heme binding
NF53_RS22750	COG2894	cell division
NF53_RS22770	COG1077	Cell shape determining protein MreB Mrl
NF53_RS22790	COG0285	dihydrofolate synthase activity
NF53_RS22805	COG1388	LysM domain
NF53_RS22815	COG0113	porphobilinogen synthase activity
NF53_RS22820	COG1587	Uroporphyrinogen-III synthase
NF53_RS22830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NF53_RS22840	COG1846	Transcriptional regulator
NF53_RS22845	COG1764	response to oxidative stress
NF53_RS22860	COG0470	DNA polymerase III
NF53_RS22860	COG1067	ATP-dependent peptidase activity
NF53_RS22905	COG0622	Phosphoesterase
NF53_RS22920	COG5401	PFAM Sporulation and spore germination
NF53_RS22935	COG2197	response regulator
NF53_RS22940	COG2233	PERMEase
NF53_RS22945	COG0402	S-adenosylhomocysteine deaminase activity
NF53_RS22950	COG1983	PspC domain protein
NF53_RS22955	COG1396	sequence-specific DNA binding
NF53_RS22960	COG0697	spore germination
NF53_RS22970	COG1959	2 iron, 2 sulfur cluster binding
NF53_RS22975	COG1668	transmembrane transport
NF53_RS22980	COG4152	abc transporter atp-binding protein
NF53_RS22985	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NF53_RS22990	COG1360	Flagellar Motor Protein
NF53_RS22995	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NF53_RS23000	COG1876	peptidase activity
NF53_RS23005	COG0824	Thioesterase
NF53_RS23010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NF53_RS23015	COG1053	succinate dehydrogenase
NF53_RS23020	COG2009	succinate dehydrogenase
NF53_RS23025	COG1719	4-vinyl reductase, 4VR
NF53_RS23035	COG3118	belongs to the thioredoxin family
NF53_RS23040	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NF53_RS23045	COG2086	electron transfer activity
NF53_RS23050	COG1024	Enoyl-CoA hydratase
NF53_RS23055	COG1309	transcriptional regulator
NF53_RS23060	COG0318	PFAM AMP-dependent synthetase and ligase
NF53_RS23085	COG2318	DinB family
NF53_RS23115	COG1131	(ABC) transporter
NF53_RS23120	COG2205	protein histidine kinase activity
NF53_RS23125	COG0745	RESPONSE REGULATOR receiver
NF53_RS23135	COG4895	conserved protein (DUF2196)
NF53_RS23140	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NF53_RS23150	COG4509	Sortase family
NF53_RS23155	COG1120	ATPase activity
NF53_RS23170	COG5386	Cell surface protein
NF53_RS23180	COG5386	Cell surface protein
NF53_RS23185	COG1114	Component of the transport system for branched-chain amino acids
NF53_RS23190	COG1187	pseudouridine synthase activity
NF53_RS23205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NF53_RS23205	COG1796	DNA polymerase
NF53_RS23210	COG1286	toxin biosynthetic process
NF53_RS23255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NF53_RS23265	COG1418	mRNA catabolic process
NF53_RS23285	COG2814	Major facilitator Superfamily
NF53_RS23290	COG1566	PFAM secretion protein HlyD family protein
NF53_RS23295	COG1309	transcriptional regulator
NF53_RS23300	COG1363	Peptidase, m42
NF53_RS23325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NF53_RS23340	COG1484	DNA-dependent DNA replication
NF53_RS23345	COG3611	Membrane attachment protein
NF53_RS23355	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NF53_RS23360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NF53_RS23370	COG1971	Probably functions as a manganese efflux pump
NF53_RS23380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NF53_RS23380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NF53_RS23385	COG5002	protein histidine kinase activity
NF53_RS23390	COG0745	RESPONSE REGULATOR receiver
NF53_RS23405	COG0538	isocitrate dehydrogenase activity
NF53_RS23410	COG0372	Belongs to the citrate synthase family
NF53_RS23425	COG0628	permease
NF53_RS23430	COG3030	protein affecting phage T7 exclusion by the F plasmid
NF53_RS23455	COG1725	Transcriptional regulator
NF53_RS23460	COG0281	malic enzyme
NF53_RS23465	COG0587	DNA-directed DNA polymerase activity
NF53_RS23480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NF53_RS23495	COG4109	DRTGG domain
NF53_RS23510	COG0006	proline dipeptidase activity
NF53_RS23540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS23545	COG0662	Cupin 2, conserved barrel domain protein
NF53_RS23560	COG1028	Short-chain dehydrogenase reductase Sdr
NF53_RS23565	COG0589	response to stress
NF53_RS23600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF53_RS23625	COG0827	DNA restriction-modification system
NF53_RS23630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NF53_RS23635	COG3874	Sporulation protein YtfJ
NF53_RS23650	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NF53_RS23660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NF53_RS23675	COG1104	cysteine desulfurase activity
NF53_RS23685	COG0583	DNA-binding transcription factor activity
NF53_RS23690	COG0697	spore germination
NF53_RS23695	COG1309	transcriptional regulator
NF53_RS23700	COG1956	GAF domain-containing protein
NF53_RS23705	COG0626	cystathionine gamma-synthase activity
NF53_RS23770	COG1595	DNA-templated transcription, initiation
NF53_RS23780	COG0110	maltose O-acetyltransferase activity
NF53_RS23785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NF53_RS23790	COG0454	-acetyltransferase
NF53_RS23795	COG0517	IMP dehydrogenase activity
NF53_RS23800	COG0123	including yeast histone deacetylase and acetoin utilization protein
NF53_RS23815	COG0745	RESPONSE REGULATOR receiver
NF53_RS23820	COG5002	protein histidine kinase activity
NF53_RS23825	COG0666	response to abiotic stimulus
NF53_RS23850	COG1609	Transcriptional regulator
NF53_RS23860	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NF53_RS23860	COG1605	Chorismate mutase
NF53_RS23865	COG4851	CamS sex pheromone cAM373 precursor
NF53_RS23870	COG3118	belongs to the thioredoxin family
NF53_RS23880	COG2309	aminopeptidase activity
NF53_RS23895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS23910	COG1674	ftsk spoiiie
NF53_RS23925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NF53_RS23935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF53_RS23940	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
NF53_RS23945	COG1363	Peptidase, m42
NF53_RS23955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF53_RS23970	COG0510	thiamine kinase activity
NF53_RS23975	COG1523	belongs to the glycosyl hydrolase 13 family
NF53_RS23985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF53_RS23990	COG1349	DNA-binding transcription factor activity
NF53_RS23995	COG1187	pseudouridine synthase activity
NF53_RS24000	COG2244	polysaccharide biosynthetic process
NF53_RS24005	COG2081	HI0933 family
NF53_RS24010	COG2814	Major facilitator Superfamily
NF53_RS24020	COG3832	glyoxalase III activity
NF53_RS24040	COG1329	Transcriptional regulator
NF53_RS24065	COG0314	molybdopterin synthase activity
NF53_RS24070	COG1763	Mo-molybdopterin cofactor biosynthetic process
NF53_RS24075	COG0303	'Molybdopterin
NF53_RS24085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NF53_RS24090	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NF53_RS24110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NF53_RS24120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NF53_RS24165	COG2814	Major facilitator Superfamily
NF53_RS24170	COG0475	glutathione-regulated potassium exporter activity
NF53_RS24175	COG0490	domain, Protein
NF53_RS24180	COG0582	viral genome integration into host DNA
NF53_RS24190	COG1136	(ABC) transporter
NF53_RS24210	COG1242	4 iron, 4 sulfur cluster binding
NF53_RS24215	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NF53_RS24220	COG1131	(ABC) transporter
NF53_RS24230	COG1794	racemase activity, acting on amino acids and derivatives
NF53_RS24265	COG2267	carboxylic ester hydrolase activity
NF53_RS24270	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NF53_RS24275	COG0671	phosphoesterase, PA-phosphatase related
NF53_RS24280	COG0438	transferase activity, transferring glycosyl groups
NF53_RS24305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS24345	COG5002	protein histidine kinase activity
NF53_RS24350	COG3852	Histidine kinase
NF53_RS24355	COG2267	carboxylic ester hydrolase activity
NF53_RS24360	COG1368	sulfuric ester hydrolase activity
NF53_RS24375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NF53_RS24380	COG1116	anion transmembrane transporter activity
NF53_RS24385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NF53_RS24400	COG0546	phosphoglycolate phosphatase activity
NF53_RS24410	COG0494	nUDIX hydrolase
NF53_RS24440	COG1854	S-ribosylhomocysteine lyase activity
NF53_RS24450	COG0288	reversible hydration of carbon dioxide
NF53_RS24455	COG1271	oxidase subunit
NF53_RS24460	COG1294	oxidase, subunit
NF53_RS24475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF53_RS24495	COG1842	Phage shock protein A
NF53_RS24520	COG3859	Proton-coupled thiamine transporter YuaJ
NF53_RS24525	COG5002	protein histidine kinase activity
NF53_RS24530	COG0745	RESPONSE REGULATOR receiver
NF53_RS24555	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NF53_RS24560	COG1597	lipid kinase activity
NF53_RS24605	COG0586	Pfam SNARE associated Golgi protein
NF53_RS24615	COG0577	efflux transmembrane transporter activity
NF53_RS24620	COG1136	(ABC) transporter
NF53_RS24625	COG2207	Transcriptional regulator
NF53_RS24625	COG3708	Transcriptional regulator
NF53_RS24635	COG1131	(ABC) transporter
NF53_RS24640	COG5658	integral membrane protein
NF53_RS24645	COG0640	Transcriptional regulator
NF53_RS24650	COG0745	RESPONSE REGULATOR receiver
NF53_RS24655	COG2205	protein histidine kinase activity
NF53_RS24660	COG0577	efflux transmembrane transporter activity
NF53_RS24665	COG0577	efflux transmembrane transporter activity
NF53_RS24670	COG1136	(ABC) transporter
NF53_RS24675	COG0577	efflux transmembrane transporter activity
NF53_RS24690	COG2188	Transcriptional regulator
NF53_RS24710	COG3964	amidohydrolase
NF53_RS24730	COG4948	Mandelate Racemase Muconate Lactonizing
NF53_RS24740	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NF53_RS24745	COG0596	Alpha beta hydrolase
NF53_RS24755	COG1169	isochorismate synthase
NF53_RS24760	COG1575	Belongs to the MenA family. Type 1 subfamily
NF53_RS24765	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NF53_RS24795	COG0058	SHG alpha-glucan phosphorylase activity
NF53_RS24805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NF53_RS24920	COG0544	peptidyl-prolyl cis-trans isomerase activity
NF53_RS24955	COG1285	pathogenesis
NF53_RS24960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NF53_RS24980	COG2155	Conserved Protein
NF53_RS24985	COG1098	S1 RNA binding domain
NF53_RS24990	COG0436	Aminotransferase
NF53_RS24995	COG1522	sequence-specific DNA binding
NF53_RS25000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NF53_RS25005	COG2267	carboxylic ester hydrolase activity
NF53_RS25015	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NF53_RS25035	COG5018	Exonuclease
NF53_RS25040	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NF53_RS25060	COG2050	protein possibly involved in aromatic compounds catabolism
NF53_RS25070	COG1268	BioY protein
NF53_RS25075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NF53_RS25080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NF53_RS25100	COG2076	Multidrug Resistance protein
NF53_RS25105	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NF53_RS25120	COG3584	3D domain protein
NF53_RS25135	COG1252	NADH dehydrogenase
NF53_RS25150	COG3708	Transcriptional regulator
NF53_RS25165	COG1683	Conserved Protein
NF53_RS25175	COG0316	Belongs to the HesB IscA family
NF53_RS25190	COG1252	NADH dehydrogenase
NF53_RS25205	COG0390	transport system, permease component
NF53_RS25210	COG2824	Alkylphosphonate utilization operon protein PhnA
NF53_RS25260	COG4837	Protein of unknown function (DUF1462)
NF53_RS25265	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NF53_RS25275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NF53_RS25280	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NF53_RS25300	COG1358	cellular component organization or biogenesis
NF53_RS25310	COG2249	NAD(P)H dehydrogenase (quinone) activity
NF53_RS25315	COG0647	UMP catabolic process
NF53_RS25325	COG2445	Protein of unknown function DUF86
NF53_RS25330	COG1494	fructose-1,6-bisphosphatase
NF53_RS25350	COG4470	Protein conserved in bacteria
NF53_RS25360	COG0789	Transcriptional regulator
NF53_RS25365	COG4377	Putative membrane peptidase family (DUF2324)
NF53_RS25390	COG0739	heme binding
NF53_RS25400	COG3377	Domain of unknown function (DUF1805)
NF53_RS25405	COG0737	Belongs to the 5'-nucleotidase family
NF53_RS25410	COG0719	Fe-S assembly protein
NF53_RS25415	COG0822	iron-sulfur transferase activity
NF53_RS25420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NF53_RS25425	COG0719	Fe-S assembly protein
NF53_RS25430	COG0396	ATPase activity
NF53_RS25435	COG1464	Belongs to the NlpA lipoprotein family
NF53_RS25440	COG2011	ABC-type metal ion transport system permease component
NF53_RS25460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF53_RS25465	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NF53_RS25475	COG1393	Belongs to the ArsC family
NF53_RS25495	COG0039	L-malate dehydrogenase activity
NF53_RS25510	COG1309	transcriptional regulator
NF53_RS25515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF53_RS25520	COG1960	acyl-CoA dehydrogenase activity
NF53_RS25525	COG0183	Belongs to the thiolase family
NF53_RS25530	COG1250	3-hydroxyacyl-CoA dehydrogenase
NF53_RS25530	COG1024	Enoyl-CoA hydratase
NF53_RS25540	COG1686	Belongs to the peptidase S11 family
NF53_RS25555	COG0011	TIGRFAM Protein of
NF53_RS25560	COG0840	transmembrane signaling receptor activity
NF53_RS25575	COG2814	Major facilitator Superfamily
NF53_RS25580	COG0531	amino acid
NF53_RS25605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF53_RS25640	COG0586	Pfam SNARE associated Golgi protein
NF53_RS25650	COG1376	ErfK ybiS ycfS ynhG family protein
NF53_RS25655	COG0745	RESPONSE REGULATOR receiver
NF53_RS25660	COG5002	protein histidine kinase activity
NF53_RS25690	COG0840	transmembrane signaling receptor activity
NF53_RS25695	COG2151	metal-sulfur cluster biosynthetic enzyme
NF53_RS25700	COG3227	Zinc metalloprotease (Elastase)
NF53_RS25705	COG1741	Belongs to the pirin family
NF53_RS25720	COG0475	glutathione-regulated potassium exporter activity
NF53_RS25725	COG0490	domain, Protein
NF53_RS25735	COG1115	amino acid carrier protein
NF53_RS25740	COG0783	Belongs to the Dps family
NF53_RS25760	COG1611	Belongs to the LOG family
NF53_RS25770	COG1528	Iron-storage protein
NF53_RS25775	COG2311	Membrane
NF53_RS25780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NF53_RS25785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NF53_RS25790	COG1115	amino acid carrier protein
NF53_RS25795	COG1115	amino acid carrier protein
NF53_RS25800	COG2910	NAD(P)H-binding
NF53_RS25815	COG0656	L-ascorbic acid biosynthetic process
NF53_RS25820	COG2814	Major facilitator Superfamily
NF53_RS25825	COG1733	regulation of RNA biosynthetic process
NF53_RS25835	COG1252	NADH dehydrogenase
NF53_RS25855	COG3290	protein histidine kinase activity
NF53_RS25855	COG0840	transmembrane signaling receptor activity
NF53_RS25890	COG0488	(ABC) transporter
NF53_RS25895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF53_RS25945	COG0745	RESPONSE REGULATOR receiver
NF53_RS25960	COG0557	exoribonuclease II activity
NF53_RS25965	COG1647	Serine aminopeptidase, S33
NF53_RS25970	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NF53_RS25975	COG1346	cytolysis
NF53_RS26010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NF53_RS26025	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NF53_RS26050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NF53_RS26065	COG2323	membrane
NF53_RS26080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF53_RS26090	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NF53_RS26100	COG1051	belongs to the nudix hydrolase family
NF53_RS26110	COG0492	ferredoxin-NADP+ reductase activity
NF53_RS26115	COG0457	Tetratricopeptide repeat
NF53_RS26120	COG0110	maltose O-acetyltransferase activity
NF53_RS26140	COG1950	PFAM Membrane protein of
NF53_RS26150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NF53_RS26155	COG0556	nucleotide-excision repair
NF53_RS26170	COG0789	Transcriptional regulator
NF53_RS26190	COG0583	DNA-binding transcription factor activity
NF53_RS26200	COG0655	NAD(P)H dehydrogenase (quinone) activity
NF53_RS26205	COG0488	(ABC) transporter
NF53_RS26215	COG1132	(ABC) transporter
NF53_RS26220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NF53_RS26225	COG0793	Belongs to the peptidase S41A family
NF53_RS26225	COG3409	Peptidoglycan-binding domain 1 protein
NF53_RS26230	COG2177	Part of the ABC transporter FtsEX involved in
NF53_RS26235	COG2884	Cell division ATP-binding protein ftsE
NF53_RS26250	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NF53_RS26265	COG1131	(ABC) transporter
NF53_RS26295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NF53_RS26300	COG1278	Cold shock
NF53_RS26305	COG1040	competence protein
NF53_RS26310	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NF53_RS26315	COG0791	NLP P60 protein
NF53_RS26315	COG1388	LysM domain
NF53_RS26320	COG1733	regulation of RNA biosynthetic process
NF53_RS26325	COG1307	EDD domain protein, DegV family
NF53_RS26330	COG1739	Uncharacterized protein family UPF0029
NF53_RS26335	COG1316	TRANSCRIPTIONal
NF53_RS26340	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NF53_RS26345	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NF53_RS26350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NF53_RS26360	COG3933	PFAM sigma-54 factor interaction domain-containing protein
NF53_RS26360	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NF53_RS26380	COG1486	melibiose metabolic process
NF53_RS26385	COG1447	Phosphotransferase system cellobiose-specific component IIA
NF53_RS26390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NF53_RS26400	COG1447	Phosphotransferase system cellobiose-specific component IIA
NF53_RS26410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NF53_RS26415	COG1301	dicarboxylic acid transport
NF53_RS26430	COG1511	domain protein
NF53_RS26435	COG0583	DNA-binding transcription factor activity
NF53_RS26440	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NF53_RS26450	COG1271	oxidase subunit
NF53_RS26455	COG1294	oxidase, subunit
NF53_RS26460	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NF53_RS26470	COG1620	l-lactate permease
NF53_RS26480	COG2389	metal-binding protein
NF53_RS26490	COG1368	sulfuric ester hydrolase activity
NF53_RS26500	COG1388	LysM domain
NF53_RS26500	COG0791	NLP P60 protein
NF53_RS26505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NF53_RS26515	COG1215	transferase activity, transferring glycosyl groups
NF53_RS26525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NF53_RS26530	COG1388	LysM domain
NF53_RS26530	COG3584	3D domain protein
NF53_RS26555	COG4715	Zinc finger, swim domain protein
NF53_RS26560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NF53_RS26600	COG0577	efflux transmembrane transporter activity
NF53_RS26605	COG1136	(ABC) transporter
NF53_RS26630	COG5002	protein histidine kinase activity
NF53_RS26635	COG0745	RESPONSE REGULATOR receiver
NF53_RS26650	COG1091	dTDP-4-dehydrorhamnose reductase activity
NF53_RS26665	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NF53_RS26675	COG0438	transferase activity, transferring glycosyl groups
NF53_RS26680	COG0438	transferase activity, transferring glycosyl groups
NF53_RS26715	COG0686	Belongs to the AlaDH PNT family
NF53_RS26735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NF53_RS26740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NF53_RS26745	COG4464	protein tyrosine phosphatase activity
NF53_RS26750	COG0489	protein tyrosine kinase activity
NF53_RS26755	COG3944	biosynthesis protein
NF53_RS26760	COG0489	protein tyrosine kinase activity
NF53_RS26775	COG1609	Transcriptional regulator
NF53_RS26785	COG0739	heme binding
NF53_RS26800	COG3279	Response regulator of the LytR AlgR family
NF53_RS26805	COG2385	sporulation resulting in formation of a cellular spore
NF53_RS26820	COG4836	Membrane
NF53_RS26825	COG1007	ATP synthesis coupled electron transport
NF53_RS26830	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NF53_RS26835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NF53_RS26845	COG0839	Belongs to the complex I subunit 6 family
NF53_RS26865	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NF53_RS26880	COG3300	MHYT domain
NF53_RS26880	COG5001	Diguanylate cyclase
NF53_RS26930	COG0356	it plays a direct role in the translocation of protons across the membrane
NF53_RS26965	COG0698	ribose 5-phosphate isomerase
NF53_RS26980	COG2259	Doxx family
NF53_RS26985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NF53_RS27000	COG0009	L-threonylcarbamoyladenylate synthase
NF53_RS27035	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NF53_RS27045	COG1494	fructose-1,6-bisphosphatase
NF53_RS27065	COG4821	SIS domain
NF53_RS27085	COG1960	acyl-CoA dehydrogenase activity
NF53_RS27090	COG1960	acyl-CoA dehydrogenase activity
NF53_RS27095	COG1250	3-hydroxyacyl-CoA dehydrogenase
NF53_RS27100	COG0183	Belongs to the thiolase family
NF53_RS27105	COG2181	nitrate reductase activity
NF53_RS27105	COG0247	lactate metabolic process
NF53_RS27110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NF53_RS27120	COG3300	MHYT domain
NF53_RS27120	COG5001	Diguanylate cyclase
NF53_RS27135	COG3227	Zinc metalloprotease (Elastase)
NF53_RS27140	COG2197	response regulator
NF53_RS27145	COG4585	Histidine kinase
NF53_RS27150	COG0842	Transport permease protein
NF53_RS27155	COG1131	(ABC) transporter
NF53_RS27160	COG0024	Methionine aminopeptidase
NF53_RS27170	COG2234	aminopeptidase activity
NF53_RS27190	COG1595	DNA-templated transcription, initiation
NF53_RS27205	COG4506	Protein conserved in bacteria
NF53_RS27210	COG1619	proteins homologs of microcin C7 resistance protein MccF
NF53_RS27235	COG2814	Major facilitator Superfamily
NF53_RS27240	COG0789	Transcriptional regulator
NF53_RS27245	COG0584	glycerophosphoryl diester phosphodiesterase
NF53_RS27250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF53_RS27260	COG1994	Peptidase M50
NF53_RS27270	COG1078	dGTPase activity
NF53_RS27275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NF53_RS27280	COG1120	ATPase activity
NF53_RS27285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF53_RS27290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF53_RS27310	COG0280	phosphate acetyltransferase
NF53_RS27325	COG3773	Cell wall hydrolase
NF53_RS27335	COG2363	Small membrane protein
NF53_RS27345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NF53_RS27350	COG2233	PERMEase
NF53_RS27355	COG0561	phosphatase activity
NF53_RS27360	COG2814	Major facilitator Superfamily
NF53_RS27370	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NF53_RS27375	COG1131	(ABC) transporter
NF53_RS27380	COG2755	lipolytic protein G-D-S-L family
NF53_RS27385	COG1609	Transcriptional regulator
NF53_RS27395	COG0460	homoserine dehydrogenase
NF53_RS27405	COG2873	o-acetylhomoserine
NF53_RS27415	COG1011	Hydrolase
NF53_RS27420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NF53_RS27430	COG2197	response regulator
NF53_RS27435	COG4585	Histidine kinase
NF53_RS27435	COG2203	Gaf domain
NF53_RS27440	COG0351	phosphomethylpyrimidine kinase
NF53_RS27445	COG3706	GGDEF domain
NF53_RS27450	COG2879	small protein
NF53_RS27455	COG1966	Carbon starvation protein
NF53_RS27460	COG3279	Response regulator of the LytR AlgR family
NF53_RS27465	COG0477	Major facilitator Superfamily
NF53_RS27475	COG0438	transferase activity, transferring glycosyl groups
NF53_RS27490	COG0840	transmembrane signaling receptor activity
NF53_RS27500	COG1607	acyl-coa hydrolase
NF53_RS27510	COG1216	Glycosyl transferase, family 2
NF53_RS27525	COG0463	Glycosyl transferase, family 2
NF53_RS27530	COG0488	(ABC) transporter
NF53_RS27535	COG1309	transcriptional regulator
NF53_RS27540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NF53_RS27545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NF53_RS27545	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NF53_RS27550	COG0628	permease
NF53_RS27570	COG3275	phosphorelay sensor kinase activity
NF53_RS27575	COG2814	Major facilitator Superfamily
NF53_RS27580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NF53_RS27585	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NF53_RS27605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NF53_RS27610	COG1272	protein, Hemolysin III
NF53_RS27640	COG5002	protein histidine kinase activity
NF53_RS27655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NF53_RS27660	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NF53_RS27665	COG4853	Protein conserved in bacteria
NF53_RS27675	COG5002	protein histidine kinase activity
NF53_RS27680	COG0745	RESPONSE REGULATOR receiver
NF53_RS27710	COG0305	Participates in initiation and elongation during chromosome replication
NF53_RS27720	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NF53_RS27745	COG0012	GTP binding
NF53_RS27750	COG4481	Protein conserved in bacteria
NF53_RS27755	COG0668	transmembrane transport
NF53_RS27765	COG1475	DNA binding
NF53_RS27770	COG1192	Involved in chromosome partitioning
NF53_RS27795	COG1847	R3H domain protein
NF53_RS27810	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NF53_RS27820	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NF53_RS27910	COG0187	DNA topoisomerase II activity
NF53_RS28105	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NF53_RS28110	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NF53_RS28425	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NF53_RS28775	COG1982	Orn Lys Arg decarboxylase major
NF53_RS28880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NF53_RS29115	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NF53_RS29230	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NF53_RS29240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NF53_RS29325	COG0512	Glutamine amidotransferase of anthranilate synthase
NF53_RS29415	COG0542	response to heat
NF53_RS29785	COG4166	transmembrane transport
NF53_RS30220	COG2208	phosphoserine phosphatase activity
NF53_RS30360	COG4956	integral membrane protein (PIN domain superfamily)
NF53_RS30570	COG0489	protein tyrosine kinase activity
NF53_RS30905	COG2183	response to ionizing radiation
NF53_RS31260	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine