locus-tag	class	description
HIS92_RS00030	COG4637	Psort location Cytoplasmic, score
HIS92_RS00050	COG3397	chitin binding
HIS92_RS00065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HIS92_RS00070	COG1115	amino acid carrier protein
HIS92_RS00075	COG1012	belongs to the aldehyde dehydrogenase family
HIS92_RS00080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIS92_RS00090	COG3938	Belongs to the proline racemase family
HIS92_RS00095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HIS92_RS00140	COG0586	Pfam SNARE associated Golgi protein
HIS92_RS00150	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HIS92_RS00155	COG4166	transmembrane transport
HIS92_RS00165	COG4948	Mandelate Racemase Muconate Lactonizing
HIS92_RS00180	COG0667	Aldo Keto reductase
HIS92_RS00225	COG5002	protein histidine kinase activity
HIS92_RS00225	COG3850	Histidine kinase
HIS92_RS00230	COG0745	RESPONSE REGULATOR receiver
HIS92_RS00255	COG1164	Oligoendopeptidase f
HIS92_RS00260	COG1307	EDD domain protein, DegV family
HIS92_RS00300	COG2814	Major facilitator Superfamily
HIS92_RS00310	COG1664	Polymer-forming cytoskeletal
HIS92_RS00315	COG0789	Transcriptional regulator
HIS92_RS00320	COG4533	DNA binding
HIS92_RS00325	COG2814	Major facilitator Superfamily
HIS92_RS00325	COG0477	Major facilitator Superfamily
HIS92_RS00350	COG2261	transglycosylase associated protein
HIS92_RS00365	COG2226	methyltransferase
HIS92_RS00400	COG0436	Aminotransferase
HIS92_RS00405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HIS92_RS00450	COG0628	permease
HIS92_RS00465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HIS92_RS00470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HIS92_RS00500	COG2746	aminoglycoside 3-N-acetyltransferase activity
HIS92_RS00510	COG0697	spore germination
HIS92_RS00515	COG2318	DinB family
HIS92_RS00535	COG4912	Dna alkylation repair
HIS92_RS00540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HIS92_RS00545	COG0346	lactoylglutathione lyase activity
HIS92_RS00550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIS92_RS00580	COG0861	Integral membrane protein TerC family
HIS92_RS00585	COG1368	sulfuric ester hydrolase activity
HIS92_RS00590	COG0488	(ABC) transporter
HIS92_RS00595	COG2409	Drug exporters of the RND superfamily
HIS92_RS00595	COG1033	growth of symbiont in host cell
HIS92_RS00600	COG1309	transcriptional regulator
HIS92_RS00615	COG0287	Prephenate dehydrogenase
HIS92_RS00630	COG1605	Chorismate mutase
HIS92_RS00630	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HIS92_RS00665	COG1388	LysM domain
HIS92_RS00665	COG3584	3D domain protein
HIS92_RS00695	COG1879	ABC-type sugar transport system periplasmic component
HIS92_RS00705	COG1172	Belongs to the binding-protein-dependent transport system permease family
HIS92_RS00715	COG2390	Transcriptional regulator
HIS92_RS00720	COG1070	Carbohydrate kinase
HIS92_RS00745	COG2329	Antibiotic biosynthesis monooxygenase
HIS92_RS00760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIS92_RS00775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIS92_RS00780	COG4187	Peptidase family M20/M25/M40
HIS92_RS00785	COG1414	Transcriptional regulator
HIS92_RS00790	COG0833	amino acid
HIS92_RS00800	COG1690	Belongs to the RtcB family
HIS92_RS00810	COG3239	Fatty acid desaturase
HIS92_RS00820	COG2720	vancomycin resistance protein
HIS92_RS00825	COG1785	Belongs to the alkaline phosphatase family
HIS92_RS00835	COG3655	Transcriptional regulator
HIS92_RS00855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HIS92_RS00860	COG0346	lactoylglutathione lyase activity
HIS92_RS00880	COG0714	Associated with various cellular activities
HIS92_RS00905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HIS92_RS00910	COG0753	catalase activity
HIS92_RS00970	COG0778	Nitroreductase
HIS92_RS00975	COG1846	Transcriptional regulator
HIS92_RS00995	COG3831	ATPase activity
HIS92_RS00995	COG4884	unkown
HIS92_RS01005	COG1136	(ABC) transporter
HIS92_RS01025	COG2207	Transcriptional regulator
HIS92_RS01030	COG0456	acetyltransferase
HIS92_RS01040	COG2816	NAD+ diphosphatase activity
HIS92_RS01045	COG0697	spore germination
HIS92_RS01050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HIS92_RS01095	COG0730	response to heat
HIS92_RS01105	COG0833	amino acid
HIS92_RS01150	COG1329	Transcriptional regulator
HIS92_RS01160	COG5002	protein histidine kinase activity
HIS92_RS01215	COG1984	allophanate hydrolase subunit 2
HIS92_RS01220	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HIS92_RS01225	COG1414	Transcriptional regulator
HIS92_RS01240	COG0640	Transcriptional regulator
HIS92_RS01250	COG1960	acyl-CoA dehydrogenase activity
HIS92_RS01305	COG3848	Pyruvate phosphate dikinase
HIS92_RS01305	COG0574	Belongs to the PEP-utilizing enzyme family
HIS92_RS01310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIS92_RS01330	COG1063	alcohol dehydrogenase
HIS92_RS01340	COG1027	Aspartate ammonia-lyase
HIS92_RS01350	COG1396	sequence-specific DNA binding
HIS92_RS01380	COG5002	protein histidine kinase activity
HIS92_RS01405	COG2207	Transcriptional regulator
HIS92_RS01420	COG0322	excinuclease ABC activity
HIS92_RS01425	COG0531	amino acid
HIS92_RS01430	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIS92_RS01440	COG0531	amino acid
HIS92_RS01450	COG0784	Response regulator, receiver
HIS92_RS01455	COG4191	Histidine kinase
HIS92_RS01465	COG1115	amino acid carrier protein
HIS92_RS01475	COG2124	cytochrome p450
HIS92_RS01490	COG0737	Belongs to the 5'-nucleotidase family
HIS92_RS01500	COG1335	isochorismatase
HIS92_RS01520	COG0583	DNA-binding transcription factor activity
HIS92_RS01525	COG1846	Transcriptional regulator
HIS92_RS01530	COG0598	Magnesium transport protein CorA
HIS92_RS01550	COG1073	alpha beta
HIS92_RS01570	COG0415	Belongs to the DNA photolyase family
HIS92_RS01575	COG0288	reversible hydration of carbon dioxide
HIS92_RS01585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HIS92_RS01590	COG5609	conserved protein (DUF2294)
HIS92_RS01605	COG1575	Belongs to the MenA family. Type 1 subfamily
HIS92_RS01610	COG0803	Belongs to the bacterial solute-binding protein 9 family
HIS92_RS01615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HIS92_RS01620	COG1121	(ABC) transporter
HIS92_RS01640	COG0798	PFAM Bile acid sodium symporter
HIS92_RS01645	COG0346	lactoylglutathione lyase activity
HIS92_RS01650	COG0640	Transcriptional regulator
HIS92_RS01660	COG0583	DNA-binding transcription factor activity
HIS92_RS01700	COG1476	TRANSCRIPTIONal
HIS92_RS01710	COG0825	malonyl-CoA metabolic process
HIS92_RS01720	COG3320	Male sterility
HIS92_RS01720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIS92_RS01725	COG1309	transcriptional regulator
HIS92_RS01730	COG1028	Short-chain dehydrogenase reductase Sdr
HIS92_RS01735	COG1522	sequence-specific DNA binding
HIS92_RS01750	COG0346	lactoylglutathione lyase activity
HIS92_RS01775	COG0745	RESPONSE REGULATOR receiver
HIS92_RS01820	COG0277	FAD linked oxidase domain protein
HIS92_RS01830	COG1136	(ABC) transporter
HIS92_RS01865	COG2814	Major facilitator Superfamily
HIS92_RS01875	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HIS92_RS01895	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HIS92_RS01915	COG0577	efflux transmembrane transporter activity
HIS92_RS01935	COG3850	Histidine kinase
HIS92_RS01935	COG5002	protein histidine kinase activity
HIS92_RS01945	COG2364	Membrane
HIS92_RS01950	COG1846	Transcriptional regulator
HIS92_RS01955	COG0456	acetyltransferase
HIS92_RS01960	COG2808	Putative FMN-binding domain
HIS92_RS01965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIS92_RS01990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HIS92_RS02010	COG0662	Cupin 2, conserved barrel domain protein
HIS92_RS02015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HIS92_RS02015	COG2207	Transcriptional regulator
HIS92_RS02030	COG5632	N-Acetylmuramoyl-L-alanine amidase
HIS92_RS02030	COG3409	Peptidoglycan-binding domain 1 protein
HIS92_RS02045	COG2814	Major facilitator Superfamily
HIS92_RS02100	COG4282	regulation of fungal-type cell wall biogenesis
HIS92_RS02145	COG5444	nuclease activity
HIS92_RS02170	COG1876	peptidase activity
HIS92_RS02175	COG2843	Capsule synthesis protein
HIS92_RS02185	COG0477	Major facilitator Superfamily
HIS92_RS02200	COG1846	Transcriptional regulator
HIS92_RS02205	COG2814	Major facilitator Superfamily
HIS92_RS02215	COG2031	fatty acid transporter
HIS92_RS02230	COG2249	NAD(P)H dehydrogenase (quinone) activity
HIS92_RS02280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HIS92_RS02285	COG1288	antiporter activity
HIS92_RS02290	COG2356	endonuclease I
HIS92_RS02300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HIS92_RS02305	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HIS92_RS02325	COG1733	regulation of RNA biosynthetic process
HIS92_RS02330	COG0778	Nitroreductase
HIS92_RS02360	COG1028	Short-chain dehydrogenase reductase Sdr
HIS92_RS02370	COG1131	(ABC) transporter
HIS92_RS02395	COG1011	Hydrolase
HIS92_RS02415	COG1051	belongs to the nudix hydrolase family
HIS92_RS02425	COG0346	lactoylglutathione lyase activity
HIS92_RS02430	COG1940	carbohydrate kinase activity
HIS92_RS02435	COG0738	Major facilitator superfamily
HIS92_RS02440	COG0110	maltose O-acetyltransferase activity
HIS92_RS02450	COG1136	(ABC) transporter
HIS92_RS02470	COG0628	permease
HIS92_RS02500	COG0500	methyltransferase
HIS92_RS02510	COG0477	Major facilitator Superfamily
HIS92_RS02540	COG1253	flavin adenine dinucleotide binding
HIS92_RS02545	COG0789	Transcriptional regulator
HIS92_RS02550	COG0697	spore germination
HIS92_RS02565	COG1357	PFAM Pentapeptide repeats (8 copies)
HIS92_RS02570	COG3813	Protein conserved in bacteria
HIS92_RS02575	COG2706	6-phosphogluconolactonase activity
HIS92_RS02580	COG1070	Carbohydrate kinase
HIS92_RS02585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HIS92_RS02590	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HIS92_RS02595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HIS92_RS02600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HIS92_RS02620	COG0814	amino acid
HIS92_RS02650	COG1733	regulation of RNA biosynthetic process
HIS92_RS02655	COG2188	Transcriptional regulator
HIS92_RS02660	COG0673	inositol 2-dehydrogenase activity
HIS92_RS02680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIS92_RS02705	COG0384	phenazine biosynthesis protein PhzF
HIS92_RS02715	COG0318	PFAM AMP-dependent synthetase and ligase
HIS92_RS02720	COG2249	NAD(P)H dehydrogenase (quinone) activity
HIS92_RS02725	COG1733	regulation of RNA biosynthetic process
HIS92_RS02730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HIS92_RS02755	COG1191	sigma factor activity
HIS92_RS02800	COG1151	hydroxylamine reductase activity
HIS92_RS02835	COG2072	flavoprotein involved in K transport
HIS92_RS02865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIS92_RS02870	COG0604	alcohol dehydrogenase
HIS92_RS02875	COG1113	amino acid transport
HIS92_RS02880	COG2814	Major facilitator Superfamily
HIS92_RS02910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HIS92_RS02915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HIS92_RS02925	COG1247	-acetyltransferase
HIS92_RS02930	COG3739	integral membrane protein
HIS92_RS02960	COG0583	DNA-binding transcription factor activity
HIS92_RS02980	COG1193	negative regulation of DNA recombination
HIS92_RS02995	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HIS92_RS03000	COG1164	Oligoendopeptidase f
HIS92_RS03035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HIS92_RS03060	COG0584	glycerophosphoryl diester phosphodiesterase
HIS92_RS03070	COG0640	Transcriptional regulator
HIS92_RS03075	COG0604	alcohol dehydrogenase
HIS92_RS03085	COG0457	Tetratricopeptide repeat
HIS92_RS03095	COG0385	Bile acid
HIS92_RS03100	COG0277	FAD linked oxidase domain protein
HIS92_RS03120	COG1252	NADH dehydrogenase
HIS92_RS03135	COG4641	Protein conserved in bacteria
HIS92_RS03145	COG2089	acid synthase
HIS92_RS03160	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HIS92_RS03165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HIS92_RS03170	COG1088	dTDP-glucose 4,6-dehydratase activity
HIS92_RS03180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HIS92_RS03185	COG0463	Glycosyl transferase, family 2
HIS92_RS03190	COG0463	Glycosyl transferase, family 2
HIS92_RS03200	COG0823	Involved in the tonB-independent uptake of proteins
HIS92_RS03205	COG3397	chitin binding
HIS92_RS03215	COG0697	spore germination
HIS92_RS03235	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HIS92_RS03255	COG0457	Tetratricopeptide repeat
HIS92_RS03310	COG1309	transcriptional regulator
HIS92_RS03325	COG1876	peptidase activity
HIS92_RS03350	COG3852	Histidine kinase
HIS92_RS03360	COG1285	pathogenesis
HIS92_RS03370	COG2514	catechol 2,3-dioxygenase activity
HIS92_RS03375	COG2720	vancomycin resistance protein
HIS92_RS03415	COG0716	FMN binding
HIS92_RS03425	COG1051	belongs to the nudix hydrolase family
HIS92_RS03445	COG1028	Short-chain dehydrogenase reductase Sdr
HIS92_RS03455	COG0165	Argininosuccinate lyase
HIS92_RS03470	COG4145	pantothenate transmembrane transporter activity
HIS92_RS03480	COG1012	belongs to the aldehyde dehydrogenase family
HIS92_RS03485	COG1028	Short-chain dehydrogenase reductase Sdr
HIS92_RS03495	COG1657	PFAM Prenyltransferase squalene oxidase
HIS92_RS03500	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HIS92_RS03505	COG2962	Rard protein
HIS92_RS03510	COG3326	Membrane
HIS92_RS03525	COG0489	protein tyrosine kinase activity
HIS92_RS03535	COG0314	molybdopterin synthase activity
HIS92_RS03540	COG0303	'Molybdopterin
HIS92_RS03545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HIS92_RS03550	COG2116	formate transmembrane transporter activity
HIS92_RS03560	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HIS92_RS03565	COG5609	conserved protein (DUF2294)
HIS92_RS03570	COG2427	Protein of unknown function (DUF1641)
HIS92_RS03575	COG3383	formate dehydrogenase (NAD+) activity
HIS92_RS03625	COG2226	methyltransferase
HIS92_RS03630	COG4166	transmembrane transport
HIS92_RS03635	COG4166	transmembrane transport
HIS92_RS03645	COG4166	transmembrane transport
HIS92_RS03650	COG1301	dicarboxylic acid transport
HIS92_RS03655	COG1316	TRANSCRIPTIONal
HIS92_RS03665	COG1595	DNA-templated transcription, initiation
HIS92_RS03675	COG1131	(ABC) transporter
HIS92_RS03695	COG0673	inositol 2-dehydrogenase activity
HIS92_RS03700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIS92_RS03705	COG0187	DNA topoisomerase II activity
HIS92_RS03710	COG1832	CoA-binding protein
HIS92_RS03715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIS92_RS03720	COG0745	RESPONSE REGULATOR receiver
HIS92_RS03740	COG4841	protein insertion into membrane
HIS92_RS03745	COG0824	Thioesterase
HIS92_RS03770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HIS92_RS03780	COG1122	ATPase activity
HIS92_RS03785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HIS92_RS03815	COG2211	Major facilitator Superfamily
HIS92_RS03825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HIS92_RS03840	COG0183	Belongs to the thiolase family
HIS92_RS03845	COG0318	PFAM AMP-dependent synthetase and ligase
HIS92_RS03850	COG1268	BioY protein
HIS92_RS03855	COG0318	PFAM AMP-dependent synthetase and ligase
HIS92_RS03860	COG1396	sequence-specific DNA binding
HIS92_RS03895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIS92_RS03905	COG5002	protein histidine kinase activity
HIS92_RS03910	COG0400	carboxylic ester hydrolase activity
HIS92_RS03915	COG0346	lactoylglutathione lyase activity
HIS92_RS03920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIS92_RS03930	COG0069	glutamate synthase activity
HIS92_RS03935	COG1902	pentaerythritol trinitrate reductase activity
HIS92_RS03940	COG1329	Transcriptional regulator
HIS92_RS03945	COG0010	Belongs to the arginase family
HIS92_RS03995	COG4846	Membrane protein involved in cytochrome C biogenesis
HIS92_RS04000	COG0785	Cytochrome C biogenesis protein
HIS92_RS04010	COG1473	amidohydrolase
HIS92_RS04020	COG1131	(ABC) transporter
HIS92_RS04040	COG0583	DNA-binding transcription factor activity
HIS92_RS04050	COG1346	cytolysis
HIS92_RS04065	COG0730	response to heat
HIS92_RS04090	COG1132	(ABC) transporter
HIS92_RS04095	COG1132	(ABC) transporter
HIS92_RS04130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HIS92_RS04135	COG0737	Belongs to the 5'-nucleotidase family
HIS92_RS04145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HIS92_RS04165	COG1695	Transcriptional regulator
HIS92_RS04175	COG0741	lytic transglycosylase activity
HIS92_RS04175	COG1196	nuclear chromosome segregation
HIS92_RS04175	COG0739	heme binding
HIS92_RS04180	COG0741	lytic transglycosylase activity
HIS92_RS04215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIS92_RS04220	COG0174	glutamine synthetase
HIS92_RS04225	COG0789	Transcriptional regulator
HIS92_RS04230	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HIS92_RS04235	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIS92_RS04240	COG2860	membrane
HIS92_RS04250	COG0464	growth
HIS92_RS04280	COG3584	3D domain protein
HIS92_RS04280	COG1388	LysM domain
HIS92_RS04285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HIS92_RS04285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HIS92_RS04285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HIS92_RS04290	COG1105	Belongs to the carbohydrate kinase PfkB family
HIS92_RS04295	COG1349	DNA-binding transcription factor activity
HIS92_RS04300	COG1979	alcohol dehydrogenase
HIS92_RS04305	COG2322	membrane
HIS92_RS04315	COG1113	amino acid transport
HIS92_RS04330	COG1408	metallophosphoesterase
HIS92_RS04335	COG2116	formate transmembrane transporter activity
HIS92_RS04350	COG2217	Heavy metal translocating P-type atpase
HIS92_RS04355	COG2608	mercury ion transmembrane transporter activity
HIS92_RS04360	COG1937	Protein conserved in bacteria
HIS92_RS04380	COG2819	hydrolase of the alpha beta superfamily
HIS92_RS04385	COG1120	ATPase activity
HIS92_RS04390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIS92_RS04395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIS92_RS04400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HIS92_RS04405	COG0708	Exodeoxyribonuclease III
HIS92_RS04410	COG2169	Transcriptional regulator
HIS92_RS04415	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIS92_RS04420	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HIS92_RS04430	COG2364	Membrane
HIS92_RS04445	COG2267	carboxylic ester hydrolase activity
HIS92_RS04450	COG5001	Diguanylate cyclase
HIS92_RS04450	COG3300	MHYT domain
HIS92_RS04485	COG1346	cytolysis
HIS92_RS04495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HIS92_RS04505	COG0840	transmembrane signaling receptor activity
HIS92_RS04515	COG1404	Belongs to the peptidase S8 family
HIS92_RS04520	COG3773	Cell wall hydrolase
HIS92_RS04530	COG1368	sulfuric ester hydrolase activity
HIS92_RS04535	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HIS92_RS04560	COG4550	Control of competence regulator ComK, YlbF/YmcA
HIS92_RS04570	COG1013	pyruvate-flavodoxin oxidoreductase activity
HIS92_RS04575	COG0674	pyruvate-flavodoxin oxidoreductase activity
HIS92_RS04575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HIS92_RS04585	COG2359	stage V sporulation protein S
HIS92_RS04590	COG1692	metallophosphoesterase
HIS92_RS04610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIS92_RS04615	COG1426	Protein conserved in bacteria
HIS92_RS04630	COG0300	oxidoreductase activity
HIS92_RS04635	COG0612	Peptidase, M16
HIS92_RS04640	COG0612	Peptidase, M16
HIS92_RS04665	COG2188	Transcriptional regulator
HIS92_RS04680	COG0740	serine-type endopeptidase activity
HIS92_RS04685	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIS92_RS04695	COG0527	aspartate kinase activity
HIS92_RS04700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIS92_RS04705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HIS92_RS04825	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HIS92_RS04830	COG1278	Cold shock
HIS92_RS04835	COG0582	viral genome integration into host DNA
HIS92_RS04870	COG0305	Participates in initiation and elongation during chromosome replication
HIS92_RS04915	COG1396	sequence-specific DNA binding
HIS92_RS04940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIS92_RS04945	COG1873	PFAM PRC-barrel domain
HIS92_RS04950	COG0612	Peptidase, M16
HIS92_RS04955	COG0726	polysaccharide deacetylase
HIS92_RS04970	COG0196	riboflavin kinase activity
HIS92_RS04980	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HIS92_RS04985	COG1550	Protein conserved in bacteria
HIS92_RS04995	COG1358	cellular component organization or biogenesis
HIS92_RS05000	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HIS92_RS05005	COG0195	Participates in both transcription termination and antitermination
HIS92_RS05025	COG0750	zinc metalloprotease
HIS92_RS05035	COG4589	Belongs to the CDS family
HIS92_RS05080	COG4974	Belongs to the 'phage' integrase family
HIS92_RS05090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIS92_RS05095	COG0758	DNA mediated transformation
HIS92_RS05100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HIS92_RS05140	COG1837	Belongs to the UPF0109 family
HIS92_RS05150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HIS92_RS05160	COG0552	protein localization to endoplasmic reticulum
HIS92_RS05165	COG1196	nuclear chromosome segregation
HIS92_RS05175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIS92_RS05180	COG1028	Short-chain dehydrogenase reductase Sdr
HIS92_RS05185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HIS92_RS05200	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HIS92_RS05205	COG1461	Dihydroxyacetone kinase
HIS92_RS05210	COG1302	Protein conserved in bacteria
HIS92_RS05225	COG1564	THIamine pyrophosphokinase
HIS92_RS05230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HIS92_RS05240	COG0515	serine threonine protein kinase
HIS92_RS05240	COG2815	serine threonine protein kinase
HIS92_RS05245	COG0631	protein serine/threonine phosphatase activity
HIS92_RS05255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HIS92_RS05255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HIS92_RS05270	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIS92_RS05275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HIS92_RS05295	COG1561	YicC-like family, N-terminal region
HIS92_RS05300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HIS92_RS05310	COG0006	proline dipeptidase activity
HIS92_RS05330	COG3069	C4-dicarboxylate transmembrane transporter activity
HIS92_RS05390	COG0564	pseudouridine synthase activity
HIS92_RS05410	COG3599	regulation of cell shape
HIS92_RS05415	COG2302	S4 RNA-binding domain
HIS92_RS05420	COG0762	integral membrane protein
HIS92_RS05430	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HIS92_RS05440	COG1873	PFAM PRC-barrel domain
HIS92_RS05445	COG1191	sigma factor activity
HIS92_RS05450	COG1191	sigma factor activity
HIS92_RS05460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HIS92_RS05465	COG0849	cell division
HIS92_RS05485	COG0772	Belongs to the SEDS family
HIS92_RS05505	COG0768	penicillin binding
HIS92_RS05530	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIS92_RS05545	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HIS92_RS05550	COG1399	metal-binding, possibly nucleic acid-binding protein
HIS92_RS05560	COG3480	Lon protease (S16) C-terminal proteolytic domain
HIS92_RS05565	COG1752	Esterase of the alpha-beta hydrolase superfamily
HIS92_RS05570	COG3314	Sporulation integral membrane protein YlbJ
HIS92_RS05580	COG0742	ribosomal rna small subunit methyltransferase
HIS92_RS05595	COG3679	Belongs to the UPF0342 family
HIS92_RS05600	COG0406	alpha-ribazole phosphatase activity
HIS92_RS05615	COG2340	Cysteine-rich secretory protein family
HIS92_RS05630	COG3336	cytochrome c oxidase
HIS92_RS05665	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HIS92_RS05670	COG0772	Belongs to the SEDS family
HIS92_RS05680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HIS92_RS05685	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HIS92_RS05695	COG4896	Protein conserved in bacteria
HIS92_RS05720	COG0483	inositol monophosphate 1-phosphatase activity
HIS92_RS05740	COG1982	Orn Lys Arg decarboxylase major
HIS92_RS05790	COG0022	dehydrogenase e1 component
HIS92_RS05795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HIS92_RS05810	COG0561	phosphatase activity
HIS92_RS05820	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIS92_RS05825	COG0569	domain protein
HIS92_RS05845	COG0583	DNA-binding transcription factor activity
HIS92_RS05850	COG0517	IMP dehydrogenase activity
HIS92_RS05860	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
HIS92_RS05870	COG4703	Protein of unknown function (DUF1797)
HIS92_RS05885	COG2200	EAL domain
HIS92_RS05890	COG1028	Short-chain dehydrogenase reductase Sdr
HIS92_RS05895	COG1408	metallophosphoesterase
HIS92_RS05940	COG2814	Major facilitator Superfamily
HIS92_RS05960	COG3209	COG3209 Rhs family protein
HIS92_RS05970	COG2205	protein histidine kinase activity
HIS92_RS05980	COG0436	Aminotransferase
HIS92_RS05985	COG1609	Transcriptional regulator
HIS92_RS05990	COG3833	ABC-type maltose transport systems, permease component
HIS92_RS05995	COG1175	transmembrane transport
HIS92_RS06000	COG2182	Extracellular solute-binding protein
HIS92_RS06010	COG0366	Alpha amylase catalytic
HIS92_RS06015	COG3842	ATPase activity
HIS92_RS06055	COG0183	Belongs to the thiolase family
HIS92_RS06090	COG1695	Transcriptional regulator
HIS92_RS06095	COG1028	Short-chain dehydrogenase reductase Sdr
HIS92_RS06115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HIS92_RS06120	COG0436	Aminotransferase
HIS92_RS06155	COG2084	Dehydrogenase
HIS92_RS06165	COG2199	diguanylate cyclase activity
HIS92_RS06165	COG2203	Gaf domain
HIS92_RS06170	COG0778	Nitroreductase
HIS92_RS06195	COG2190	(PTS) system
HIS92_RS06195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HIS92_RS06195	COG1263	PTS System
HIS92_RS06200	COG3711	transcriptional antiterminator
HIS92_RS06210	COG2188	Transcriptional regulator
HIS92_RS06220	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HIS92_RS06245	COG1547	Domain of unknown function (DUF309)
HIS92_RS06250	COG0456	acetyltransferase
HIS92_RS06255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIS92_RS06260	COG4086	secreted protein
HIS92_RS06265	COG0561	phosphatase activity
HIS92_RS06270	COG0697	spore germination
HIS92_RS06285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HIS92_RS06310	COG0733	neurotransmitter:sodium symporter activity
HIS92_RS06330	COG1686	Belongs to the peptidase S11 family
HIS92_RS06335	COG1725	Transcriptional regulator
HIS92_RS06340	COG1131	(ABC) transporter
HIS92_RS06360	COG1846	Transcriptional regulator
HIS92_RS06375	COG0598	Magnesium transport protein CorA
HIS92_RS06400	COG4974	Belongs to the 'phage' integrase family
HIS92_RS06410	COG0735	belongs to the Fur family
HIS92_RS06415	COG1300	Membrane
HIS92_RS06435	COG0667	Aldo Keto reductase
HIS92_RS06440	COG0656	L-ascorbic acid biosynthetic process
HIS92_RS06445	COG0456	acetyltransferase
HIS92_RS06445	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HIS92_RS06455	COG4085	toxin activity
HIS92_RS06455	COG0737	Belongs to the 5'-nucleotidase family
HIS92_RS06455	COG1525	nuclease
HIS92_RS06465	COG0596	Alpha beta hydrolase
HIS92_RS06470	COG2056	Na+-H+ antiporter family
HIS92_RS06475	COG1609	Transcriptional regulator
HIS92_RS06480	COG0456	acetyltransferase
HIS92_RS06485	COG1073	alpha beta
HIS92_RS06500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HIS92_RS06500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HIS92_RS06505	COG0307	riboflavin synthase, alpha
HIS92_RS06535	COG2226	methyltransferase
HIS92_RS06535	COG1073	alpha beta
HIS92_RS06550	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HIS92_RS06565	COG0737	Belongs to the 5'-nucleotidase family
HIS92_RS06575	COG1522	sequence-specific DNA binding
HIS92_RS06620	COG0300	oxidoreductase activity
HIS92_RS06625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIS92_RS06630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIS92_RS06635	COG1760	l-serine dehydratase
HIS92_RS06640	COG1760	l-serine dehydratase
HIS92_RS06670	COG1285	pathogenesis
HIS92_RS06685	COG2195	Cleaves the N-terminal amino acid of tripeptides
HIS92_RS06690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HIS92_RS06705	COG1376	ErfK ybiS ycfS ynhG family protein
HIS92_RS06710	COG4129	membrane
HIS92_RS06715	COG1126	abc transporter atp-binding protein
HIS92_RS06720	COG0765	amino acid transport
HIS92_RS06725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HIS92_RS06745	COG2323	membrane
HIS92_RS06750	COG0772	Belongs to the SEDS family
HIS92_RS06755	COG0508	dehydrogenase complex catalyzes the overall conversion of
HIS92_RS06760	COG0022	dehydrogenase e1 component
HIS92_RS06765	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HIS92_RS06770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HIS92_RS06785	COG0280	phosphate acetyltransferase
HIS92_RS06790	COG3829	transcription factor binding
HIS92_RS06790	COG3290	protein histidine kinase activity
HIS92_RS06800	COG0584	glycerophosphoryl diester phosphodiesterase
HIS92_RS06805	COG3093	addiction module antidote protein HigA
HIS92_RS06850	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HIS92_RS06890	COG0750	zinc metalloprotease
HIS92_RS06895	COG0497	DNA recombination
HIS92_RS06905	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HIS92_RS06915	COG0142	geranyltranstransferase activity
HIS92_RS06940	COG1302	Protein conserved in bacteria
HIS92_RS06945	COG0439	Biotin carboxylase
HIS92_RS06950	COG0511	ligase activity, forming carbon-carbon bonds
HIS92_RS06995	COG3854	ATPases associated with a variety of cellular activities
HIS92_RS07020	COG0006	proline dipeptidase activity
HIS92_RS07035	COG3872	metal-dependent enzyme
HIS92_RS07045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HIS92_RS07080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIS92_RS07090	COG1609	Transcriptional regulator
HIS92_RS07100	COG2076	Multidrug Resistance protein
HIS92_RS07105	COG2076	Multidrug Resistance protein
HIS92_RS07145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HIS92_RS07175	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HIS92_RS07210	COG1459	type II secretion system
HIS92_RS07215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HIS92_RS07270	COG1410	methionine synthase
HIS92_RS07270	COG0646	methionine synthase
HIS92_RS07275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HIS92_RS07275	COG0646	methionine synthase
HIS92_RS07280	COG0626	cystathionine gamma-synthase activity
HIS92_RS07285	COG0626	cystathionine gamma-synthase activity
HIS92_RS07305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIS92_RS07315	COG1940	carbohydrate kinase activity
HIS92_RS07320	COG4483	Protein conserved in bacteria
HIS92_RS07325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HIS92_RS07330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HIS92_RS07335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HIS92_RS07340	COG0704	Plays a role in the regulation of phosphate uptake
HIS92_RS07350	COG0573	inorganic phosphate transmembrane transporter activity
HIS92_RS07355	COG0573	inorganic phosphate transmembrane transporter activity
HIS92_RS07370	COG0477	Major facilitator Superfamily
HIS92_RS07375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HIS92_RS07385	COG5521	maltodextrose utilization protein MalA
HIS92_RS07400	COG0735	belongs to the Fur family
HIS92_RS07405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HIS92_RS07410	COG1121	(ABC) transporter
HIS92_RS07415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIS92_RS07445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HIS92_RS07450	COG2384	SAM-dependent methyltransferase
HIS92_RS07460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIS92_RS07465	COG0358	DNA primase activity
HIS92_RS07470	COG1671	Belongs to the UPF0178 family
HIS92_RS07480	COG0517	IMP dehydrogenase activity
HIS92_RS07495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HIS92_RS07500	COG0295	cytidine deaminase activity
HIS92_RS07505	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HIS92_RS07515	COG1480	7TM receptor with intracellular HD hydrolase
HIS92_RS07520	COG1702	phosphate starvation-inducible protein PhoH
HIS92_RS07540	COG1610	YqeY-like protein
HIS92_RS07545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HIS92_RS07550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HIS92_RS07555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HIS92_RS07585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HIS92_RS07590	COG1733	regulation of RNA biosynthetic process
HIS92_RS07615	COG1466	dna polymerase III delta subunit
HIS92_RS07625	COG0658	competence protein
HIS92_RS07625	COG2333	competence protein COMEC
HIS92_RS07630	COG2131	deaminase
HIS92_RS07635	COG1596	polysaccharide export
HIS92_RS07635	COG1555	photosystem II stabilization
HIS92_RS07640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIS92_RS07645	COG2226	methyltransferase
HIS92_RS07650	COG0799	negative regulation of ribosome biogenesis
HIS92_RS07655	COG1713	HD superfamily hydrolase involved in NAD metabolism
HIS92_RS07665	COG1534	Rna-binding protein
HIS92_RS07675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HIS92_RS07680	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HIS92_RS07705	COG1595	DNA-templated transcription, initiation
HIS92_RS07715	COG0778	Nitroreductase
HIS92_RS07720	COG2357	RelA SpoT domain protein
HIS92_RS07730	COG1785	Belongs to the alkaline phosphatase family
HIS92_RS07740	COG2267	carboxylic ester hydrolase activity
HIS92_RS07775	COG1404	Belongs to the peptidase S8 family
HIS92_RS07780	COG3186	Phenylalanine-4-hydroxylase
HIS92_RS07790	COG2514	catechol 2,3-dioxygenase activity
HIS92_RS07795	COG2259	Doxx family
HIS92_RS07835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HIS92_RS07845	COG1454	alcohol dehydrogenase
HIS92_RS07845	COG1012	belongs to the aldehyde dehydrogenase family
HIS92_RS07850	COG0626	cystathionine gamma-synthase activity
HIS92_RS07855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HIS92_RS07880	COG0768	penicillin binding
HIS92_RS07910	COG4122	O-methyltransferase activity
HIS92_RS07915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HIS92_RS07930	COG4472	Bacterial protein of unknown function (DUF965)
HIS92_RS07945	COG0628	permease
HIS92_RS07965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HIS92_RS07980	COG1104	cysteine desulfurase activity
HIS92_RS07985	COG1959	2 iron, 2 sulfur cluster binding
HIS92_RS07990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HIS92_RS08000	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HIS92_RS08030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIS92_RS08040	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HIS92_RS08040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HIS92_RS08045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIS92_RS08050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HIS92_RS08050	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HIS92_RS08060	COG2244	polysaccharide biosynthetic process
HIS92_RS08065	COG2323	membrane
HIS92_RS08075	COG1862	Preprotein translocase
HIS92_RS08105	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HIS92_RS08135	COG0157	Belongs to the NadC ModD family
HIS92_RS08140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HIS92_RS08145	COG1104	cysteine desulfurase activity
HIS92_RS08150	COG1827	regulation of RNA biosynthetic process
HIS92_RS08155	COG2258	MOSC domain
HIS92_RS08165	COG0077	Prephenate dehydratase
HIS92_RS08170	COG0577	efflux transmembrane transporter activity
HIS92_RS08175	COG0577	efflux transmembrane transporter activity
HIS92_RS08180	COG1136	(ABC) transporter
HIS92_RS08185	COG5002	protein histidine kinase activity
HIS92_RS08190	COG0745	RESPONSE REGULATOR receiver
HIS92_RS08200	COG3290	protein histidine kinase activity
HIS92_RS08210	COG2868	ribosomal protein
HIS92_RS08220	COG1530	ribonuclease E activity
HIS92_RS08225	COG1994	Peptidase M50
HIS92_RS08230	COG0739	heme binding
HIS92_RS08235	COG2894	cell division
HIS92_RS08255	COG1077	Cell shape determining protein MreB Mrl
HIS92_RS08275	COG0285	dihydrofolate synthase activity
HIS92_RS08290	COG1388	LysM domain
HIS92_RS08300	COG0113	porphobilinogen synthase activity
HIS92_RS08305	COG1587	Uroporphyrinogen-III synthase
HIS92_RS08315	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HIS92_RS08325	COG1846	Transcriptional regulator
HIS92_RS08330	COG1764	response to oxidative stress
HIS92_RS08345	COG0470	DNA polymerase III
HIS92_RS08345	COG1067	ATP-dependent peptidase activity
HIS92_RS08395	COG0622	Phosphoesterase
HIS92_RS08410	COG5401	PFAM Sporulation and spore germination
HIS92_RS08430	COG1309	transcriptional regulator
HIS92_RS08440	COG2197	response regulator
HIS92_RS08445	COG2233	PERMEase
HIS92_RS08450	COG0402	S-adenosylhomocysteine deaminase activity
HIS92_RS08455	COG1983	PspC domain protein
HIS92_RS08460	COG1396	sequence-specific DNA binding
HIS92_RS08465	COG0697	spore germination
HIS92_RS08475	COG1959	2 iron, 2 sulfur cluster binding
HIS92_RS08480	COG1668	transmembrane transport
HIS92_RS08485	COG4152	abc transporter atp-binding protein
HIS92_RS08490	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HIS92_RS08495	COG1360	Flagellar Motor Protein
HIS92_RS08500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HIS92_RS08505	COG1876	peptidase activity
HIS92_RS08510	COG0824	Thioesterase
HIS92_RS08515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HIS92_RS08520	COG1053	succinate dehydrogenase
HIS92_RS08525	COG2009	succinate dehydrogenase
HIS92_RS08530	COG1719	4-vinyl reductase, 4VR
HIS92_RS08540	COG3118	belongs to the thioredoxin family
HIS92_RS08545	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HIS92_RS08550	COG2086	electron transfer activity
HIS92_RS08555	COG1024	Enoyl-CoA hydratase
HIS92_RS08560	COG1309	transcriptional regulator
HIS92_RS08565	COG0318	PFAM AMP-dependent synthetase and ligase
HIS92_RS08590	COG2318	DinB family
HIS92_RS08610	COG1131	(ABC) transporter
HIS92_RS08615	COG2205	protein histidine kinase activity
HIS92_RS08620	COG0745	RESPONSE REGULATOR receiver
HIS92_RS08630	COG4895	conserved protein (DUF2196)
HIS92_RS08635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HIS92_RS08645	COG4509	Sortase family
HIS92_RS08650	COG1120	ATPase activity
HIS92_RS08665	COG5386	Cell surface protein
HIS92_RS08675	COG5386	Cell surface protein
HIS92_RS08680	COG1114	Component of the transport system for branched-chain amino acids
HIS92_RS08685	COG1187	pseudouridine synthase activity
HIS92_RS08695	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HIS92_RS08695	COG1796	DNA polymerase
HIS92_RS08700	COG1286	toxin biosynthetic process
HIS92_RS08740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIS92_RS08750	COG1418	mRNA catabolic process
HIS92_RS08765	COG2814	Major facilitator Superfamily
HIS92_RS08770	COG1566	PFAM secretion protein HlyD family protein
HIS92_RS08775	COG1309	transcriptional regulator
HIS92_RS08780	COG1363	Peptidase, m42
HIS92_RS08805	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIS92_RS08820	COG1484	DNA-dependent DNA replication
HIS92_RS08825	COG3611	Membrane attachment protein
HIS92_RS08835	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HIS92_RS08840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HIS92_RS08845	COG0237	dephospho-CoA kinase activity
HIS92_RS08850	COG1971	Probably functions as a manganese efflux pump
HIS92_RS08860	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIS92_RS08860	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIS92_RS08865	COG5002	protein histidine kinase activity
HIS92_RS08870	COG0745	RESPONSE REGULATOR receiver
HIS92_RS08890	COG0538	isocitrate dehydrogenase activity
HIS92_RS08895	COG0372	Belongs to the citrate synthase family
HIS92_RS08905	COG0628	permease
HIS92_RS08910	COG3030	protein affecting phage T7 exclusion by the F plasmid
HIS92_RS08935	COG1725	Transcriptional regulator
HIS92_RS08940	COG0281	malic enzyme
HIS92_RS08945	COG0587	DNA-directed DNA polymerase activity
HIS92_RS08960	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HIS92_RS08975	COG4109	DRTGG domain
HIS92_RS08990	COG0006	proline dipeptidase activity
HIS92_RS09025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HIS92_RS09030	COG0662	Cupin 2, conserved barrel domain protein
HIS92_RS09045	COG1028	Short-chain dehydrogenase reductase Sdr
HIS92_RS09050	COG0589	response to stress
HIS92_RS09090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIS92_RS09115	COG0827	DNA restriction-modification system
HIS92_RS09120	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HIS92_RS09125	COG3874	Sporulation protein YtfJ
HIS92_RS09140	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HIS92_RS09150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HIS92_RS09165	COG1104	cysteine desulfurase activity
HIS92_RS09175	COG0583	DNA-binding transcription factor activity
HIS92_RS09180	COG0697	spore germination
HIS92_RS09185	COG1309	transcriptional regulator
HIS92_RS09190	COG1956	GAF domain-containing protein
HIS92_RS09195	COG0626	cystathionine gamma-synthase activity
HIS92_RS09220	COG0110	maltose O-acetyltransferase activity
HIS92_RS09225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HIS92_RS09230	COG0454	-acetyltransferase
HIS92_RS09235	COG0517	IMP dehydrogenase activity
HIS92_RS09240	COG0123	including yeast histone deacetylase and acetoin utilization protein
HIS92_RS09255	COG0745	RESPONSE REGULATOR receiver
HIS92_RS09260	COG5002	protein histidine kinase activity
HIS92_RS09265	COG0666	response to abiotic stimulus
HIS92_RS09300	COG1609	Transcriptional regulator
HIS92_RS09310	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HIS92_RS09310	COG1605	Chorismate mutase
HIS92_RS09315	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HIS92_RS09315	COG1605	Chorismate mutase
HIS92_RS09320	COG4851	CamS sex pheromone cAM373 precursor
HIS92_RS09325	COG3118	belongs to the thioredoxin family
HIS92_RS09335	COG2309	aminopeptidase activity
HIS92_RS09350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HIS92_RS09355	COG0697	spore germination
HIS92_RS09360	COG0789	Transcriptional regulator
HIS92_RS09375	COG1674	ftsk spoiiie
HIS92_RS09390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIS92_RS09400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HIS92_RS09405	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HIS92_RS09410	COG1363	Peptidase, m42
HIS92_RS09420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIS92_RS09435	COG0510	thiamine kinase activity
HIS92_RS09440	COG1523	belongs to the glycosyl hydrolase 13 family
HIS92_RS09450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HIS92_RS09455	COG1349	DNA-binding transcription factor activity
HIS92_RS09460	COG1187	pseudouridine synthase activity
HIS92_RS09465	COG2244	polysaccharide biosynthetic process
HIS92_RS09470	COG2081	HI0933 family
HIS92_RS09475	COG2814	Major facilitator Superfamily
HIS92_RS09485	COG3832	glyoxalase III activity
HIS92_RS09505	COG1329	Transcriptional regulator
HIS92_RS09530	COG0314	molybdopterin synthase activity
HIS92_RS09535	COG1763	Mo-molybdopterin cofactor biosynthetic process
HIS92_RS09540	COG0303	'Molybdopterin
HIS92_RS09550	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HIS92_RS09555	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HIS92_RS09575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIS92_RS09585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HIS92_RS09625	COG2814	Major facilitator Superfamily
HIS92_RS09630	COG0475	glutathione-regulated potassium exporter activity
HIS92_RS09635	COG0490	domain, Protein
HIS92_RS09640	COG0582	viral genome integration into host DNA
HIS92_RS09650	COG1136	(ABC) transporter
HIS92_RS09670	COG1242	4 iron, 4 sulfur cluster binding
HIS92_RS09675	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HIS92_RS09680	COG1794	racemase activity, acting on amino acids and derivatives
HIS92_RS09695	COG2267	carboxylic ester hydrolase activity
HIS92_RS09700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HIS92_RS09705	COG0671	phosphoesterase, PA-phosphatase related
HIS92_RS09710	COG0438	transferase activity, transferring glycosyl groups
HIS92_RS09805	COG5002	protein histidine kinase activity
HIS92_RS09810	COG3852	Histidine kinase
HIS92_RS09820	COG2267	carboxylic ester hydrolase activity
HIS92_RS09825	COG1368	sulfuric ester hydrolase activity
HIS92_RS09850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HIS92_RS09855	COG1116	anion transmembrane transporter activity
HIS92_RS09860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HIS92_RS09885	COG0494	nUDIX hydrolase
HIS92_RS09915	COG2076	Multidrug Resistance protein
HIS92_RS09920	COG2076	Multidrug Resistance protein
HIS92_RS09925	COG0789	Transcriptional regulator
HIS92_RS09930	COG1854	S-ribosylhomocysteine lyase activity
HIS92_RS09940	COG0288	reversible hydration of carbon dioxide
HIS92_RS09945	COG1271	oxidase subunit
HIS92_RS09950	COG1294	oxidase, subunit
HIS92_RS09970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIS92_RS09995	COG1842	Phage shock protein A
HIS92_RS10020	COG3859	Proton-coupled thiamine transporter YuaJ
HIS92_RS10025	COG5002	protein histidine kinase activity
HIS92_RS10030	COG0745	RESPONSE REGULATOR receiver
HIS92_RS10060	COG1597	lipid kinase activity
HIS92_RS10110	COG5002	protein histidine kinase activity
HIS92_RS10120	COG0586	Pfam SNARE associated Golgi protein
HIS92_RS10130	COG0577	efflux transmembrane transporter activity
HIS92_RS10135	COG1136	(ABC) transporter
HIS92_RS10140	COG2207	Transcriptional regulator
HIS92_RS10140	COG3708	Transcriptional regulator
HIS92_RS10150	COG1131	(ABC) transporter
HIS92_RS10155	COG5658	integral membrane protein
HIS92_RS10160	COG0640	Transcriptional regulator
HIS92_RS10170	COG0745	RESPONSE REGULATOR receiver
HIS92_RS10175	COG2205	protein histidine kinase activity
HIS92_RS10180	COG0577	efflux transmembrane transporter activity
HIS92_RS10185	COG0577	efflux transmembrane transporter activity
HIS92_RS10190	COG1136	(ABC) transporter
HIS92_RS10195	COG0577	efflux transmembrane transporter activity
HIS92_RS10210	COG2188	Transcriptional regulator
HIS92_RS10230	COG3964	amidohydrolase
HIS92_RS10250	COG4948	Mandelate Racemase Muconate Lactonizing
HIS92_RS10260	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HIS92_RS10265	COG0596	Alpha beta hydrolase
HIS92_RS10275	COG1169	isochorismate synthase
HIS92_RS10280	COG1575	Belongs to the MenA family. Type 1 subfamily
HIS92_RS10285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HIS92_RS10290	COG1278	Cold shock
HIS92_RS10315	COG0058	SHG alpha-glucan phosphorylase activity
HIS92_RS10325	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HIS92_RS10330	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HIS92_RS10355	COG1309	transcriptional regulator
HIS92_RS10490	COG1285	pathogenesis
HIS92_RS10495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HIS92_RS10510	COG2155	Conserved Protein
HIS92_RS10515	COG1098	S1 RNA binding domain
HIS92_RS10520	COG0436	Aminotransferase
HIS92_RS10525	COG1522	sequence-specific DNA binding
HIS92_RS10530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIS92_RS10535	COG2267	carboxylic ester hydrolase activity
HIS92_RS10545	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HIS92_RS10565	COG5018	Exonuclease
HIS92_RS10570	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HIS92_RS10590	COG2050	protein possibly involved in aromatic compounds catabolism
HIS92_RS10600	COG1268	BioY protein
HIS92_RS10605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HIS92_RS10610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIS92_RS10625	COG3584	3D domain protein
HIS92_RS10640	COG1252	NADH dehydrogenase
HIS92_RS10650	COG3708	Transcriptional regulator
HIS92_RS10665	COG1683	Conserved Protein
HIS92_RS10695	COG0316	Belongs to the HesB IscA family
HIS92_RS10710	COG1252	NADH dehydrogenase
HIS92_RS10720	COG2274	protein secretion by the type I secretion system
HIS92_RS10725	COG0390	transport system, permease component
HIS92_RS10730	COG2824	Alkylphosphonate utilization operon protein PhnA
HIS92_RS10770	COG4837	Protein of unknown function (DUF1462)
HIS92_RS10775	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HIS92_RS10785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HIS92_RS10790	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HIS92_RS10810	COG1358	cellular component organization or biogenesis
HIS92_RS10820	COG2249	NAD(P)H dehydrogenase (quinone) activity
HIS92_RS10825	COG0647	UMP catabolic process
HIS92_RS10835	COG2445	Protein of unknown function DUF86
HIS92_RS10840	COG1494	fructose-1,6-bisphosphatase
HIS92_RS10855	COG4470	Protein conserved in bacteria
HIS92_RS10865	COG0789	Transcriptional regulator
HIS92_RS10870	COG4377	Putative membrane peptidase family (DUF2324)
HIS92_RS10895	COG0739	heme binding
HIS92_RS10905	COG3377	Domain of unknown function (DUF1805)
HIS92_RS10910	COG0737	Belongs to the 5'-nucleotidase family
HIS92_RS10915	COG0719	Fe-S assembly protein
HIS92_RS10920	COG0822	iron-sulfur transferase activity
HIS92_RS10925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HIS92_RS10930	COG0719	Fe-S assembly protein
HIS92_RS10935	COG0396	ATPase activity
HIS92_RS10940	COG1464	Belongs to the NlpA lipoprotein family
HIS92_RS10945	COG1464	Belongs to the NlpA lipoprotein family
HIS92_RS10950	COG2011	ABC-type metal ion transport system permease component
HIS92_RS10965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HIS92_RS10970	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HIS92_RS10980	COG1393	Belongs to the ArsC family
HIS92_RS11000	COG0039	L-malate dehydrogenase activity
HIS92_RS11015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIS92_RS11020	COG1960	acyl-CoA dehydrogenase activity
HIS92_RS11025	COG0183	Belongs to the thiolase family
HIS92_RS11030	COG1250	3-hydroxyacyl-CoA dehydrogenase
HIS92_RS11030	COG1024	Enoyl-CoA hydratase
HIS92_RS11040	COG1686	Belongs to the peptidase S11 family
HIS92_RS11055	COG0011	TIGRFAM Protein of
HIS92_RS11060	COG0840	transmembrane signaling receptor activity
HIS92_RS11075	COG2814	Major facilitator Superfamily
HIS92_RS11080	COG0531	amino acid
HIS92_RS11105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIS92_RS11140	COG0586	Pfam SNARE associated Golgi protein
HIS92_RS11150	COG1376	ErfK ybiS ycfS ynhG family protein
HIS92_RS11155	COG0745	RESPONSE REGULATOR receiver
HIS92_RS11160	COG5002	protein histidine kinase activity
HIS92_RS11190	COG0840	transmembrane signaling receptor activity
HIS92_RS11195	COG2151	metal-sulfur cluster biosynthetic enzyme
HIS92_RS11205	COG3227	Zinc metalloprotease (Elastase)
HIS92_RS11225	COG0586	Pfam SNARE associated Golgi protein
HIS92_RS11230	COG0475	glutathione-regulated potassium exporter activity
HIS92_RS11235	COG0490	domain, Protein
HIS92_RS11240	COG1115	amino acid carrier protein
HIS92_RS11245	COG0783	Belongs to the Dps family
HIS92_RS11260	COG1611	Belongs to the LOG family
HIS92_RS11270	COG1528	Iron-storage protein
HIS92_RS11280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIS92_RS11285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIS92_RS11290	COG1115	amino acid carrier protein
HIS92_RS11295	COG1115	amino acid carrier protein
HIS92_RS11300	COG2910	NAD(P)H-binding
HIS92_RS11315	COG0656	L-ascorbic acid biosynthetic process
HIS92_RS11320	COG2814	Major facilitator Superfamily
HIS92_RS11325	COG1733	regulation of RNA biosynthetic process
HIS92_RS11335	COG1252	NADH dehydrogenase
HIS92_RS11355	COG0840	transmembrane signaling receptor activity
HIS92_RS11355	COG3290	protein histidine kinase activity
HIS92_RS11390	COG0488	(ABC) transporter
HIS92_RS11395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HIS92_RS11415	COG1335	isochorismatase
HIS92_RS11420	COG1522	sequence-specific DNA binding
HIS92_RS11430	COG1522	sequence-specific DNA binding
HIS92_RS11435	COG0288	reversible hydration of carbon dioxide
HIS92_RS11440	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
HIS92_RS11445	COG2233	PERMEase
HIS92_RS11490	COG0557	exoribonuclease II activity
HIS92_RS11495	COG1647	Serine aminopeptidase, S33
HIS92_RS11500	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HIS92_RS11505	COG1346	cytolysis
HIS92_RS11540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HIS92_RS11555	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HIS92_RS11580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HIS92_RS11595	COG2323	membrane
HIS92_RS11605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HIS92_RS11615	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HIS92_RS11625	COG1051	belongs to the nudix hydrolase family
HIS92_RS11635	COG0492	ferredoxin-NADP+ reductase activity
HIS92_RS11640	COG0457	Tetratricopeptide repeat
HIS92_RS11645	COG0110	maltose O-acetyltransferase activity
HIS92_RS11665	COG1950	PFAM Membrane protein of
HIS92_RS11675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HIS92_RS11695	COG0789	Transcriptional regulator
HIS92_RS11715	COG0583	DNA-binding transcription factor activity
HIS92_RS11725	COG0655	NAD(P)H dehydrogenase (quinone) activity
HIS92_RS11730	COG0488	(ABC) transporter
HIS92_RS11740	COG1132	(ABC) transporter
HIS92_RS11745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIS92_RS11750	COG3409	Peptidoglycan-binding domain 1 protein
HIS92_RS11750	COG0793	Belongs to the peptidase S41A family
HIS92_RS11755	COG2177	Part of the ABC transporter FtsEX involved in
HIS92_RS11760	COG2884	Cell division ATP-binding protein ftsE
HIS92_RS11780	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HIS92_RS11785	COG1278	Cold shock
HIS92_RS11790	COG1040	competence protein
HIS92_RS11795	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HIS92_RS11800	COG1388	LysM domain
HIS92_RS11800	COG0791	NLP P60 protein
HIS92_RS11805	COG1733	regulation of RNA biosynthetic process
HIS92_RS11810	COG1307	EDD domain protein, DegV family
HIS92_RS11815	COG1739	Uncharacterized protein family UPF0029
HIS92_RS11820	COG1316	TRANSCRIPTIONal
HIS92_RS11825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HIS92_RS11830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HIS92_RS11835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HIS92_RS11845	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HIS92_RS11845	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HIS92_RS11865	COG1486	melibiose metabolic process
HIS92_RS11870	COG1447	Phosphotransferase system cellobiose-specific component IIA
HIS92_RS11875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HIS92_RS11885	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HIS92_RS11895	COG1447	Phosphotransferase system cellobiose-specific component IIA
HIS92_RS11905	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HIS92_RS11910	COG1301	dicarboxylic acid transport
HIS92_RS11925	COG1511	domain protein
HIS92_RS11930	COG0583	DNA-binding transcription factor activity
HIS92_RS11945	COG1271	oxidase subunit
HIS92_RS11950	COG1294	oxidase, subunit
HIS92_RS11955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HIS92_RS11965	COG1620	l-lactate permease
HIS92_RS11975	COG2389	metal-binding protein
HIS92_RS11985	COG1368	sulfuric ester hydrolase activity
HIS92_RS11995	COG1388	LysM domain
HIS92_RS11995	COG0791	NLP P60 protein
HIS92_RS12000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIS92_RS12010	COG1215	transferase activity, transferring glycosyl groups
HIS92_RS12015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HIS92_RS12020	COG3584	3D domain protein
HIS92_RS12020	COG1388	LysM domain
HIS92_RS12045	COG4715	Zinc finger, swim domain protein
HIS92_RS12050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HIS92_RS12090	COG0577	efflux transmembrane transporter activity
HIS92_RS12095	COG1136	(ABC) transporter
HIS92_RS12130	COG5002	protein histidine kinase activity
HIS92_RS12135	COG0745	RESPONSE REGULATOR receiver
HIS92_RS12145	COG1316	TRANSCRIPTIONal
HIS92_RS12150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HIS92_RS12155	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HIS92_RS12160	COG1215	transferase activity, transferring glycosyl groups
HIS92_RS12165	COG0438	transferase activity, transferring glycosyl groups
HIS92_RS12185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HIS92_RS12190	COG4464	protein tyrosine phosphatase activity
HIS92_RS12195	COG0489	protein tyrosine kinase activity
HIS92_RS12200	COG3944	biosynthesis protein
HIS92_RS12205	COG0489	protein tyrosine kinase activity
HIS92_RS12220	COG1609	Transcriptional regulator
HIS92_RS12230	COG0739	heme binding
HIS92_RS12245	COG3279	Response regulator of the LytR AlgR family
HIS92_RS12250	COG2385	sporulation resulting in formation of a cellular spore
HIS92_RS12265	COG4836	Membrane
HIS92_RS12270	COG1007	ATP synthesis coupled electron transport
HIS92_RS12275	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HIS92_RS12280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HIS92_RS12290	COG0839	Belongs to the complex I subunit 6 family
HIS92_RS12310	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HIS92_RS12325	COG3300	MHYT domain
HIS92_RS12325	COG5001	Diguanylate cyclase
HIS92_RS12375	COG0356	it plays a direct role in the translocation of protons across the membrane
HIS92_RS12410	COG0698	ribose 5-phosphate isomerase
HIS92_RS12420	COG2190	(PTS) system
HIS92_RS12425	COG2259	Doxx family
HIS92_RS12430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HIS92_RS12450	COG0009	L-threonylcarbamoyladenylate synthase
HIS92_RS12485	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HIS92_RS12490	COG1494	fructose-1,6-bisphosphatase
HIS92_RS12510	COG4821	SIS domain
HIS92_RS12530	COG1960	acyl-CoA dehydrogenase activity
HIS92_RS12535	COG1960	acyl-CoA dehydrogenase activity
HIS92_RS12540	COG1250	3-hydroxyacyl-CoA dehydrogenase
HIS92_RS12545	COG0183	Belongs to the thiolase family
HIS92_RS12550	COG0247	lactate metabolic process
HIS92_RS12550	COG2181	nitrate reductase activity
HIS92_RS12555	COG3620	sequence-specific DNA binding
HIS92_RS12595	COG1404	Belongs to the peptidase S8 family
HIS92_RS12600	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HIS92_RS12645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIS92_RS12655	COG3300	MHYT domain
HIS92_RS12655	COG5001	Diguanylate cyclase
HIS92_RS12670	COG3227	Zinc metalloprotease (Elastase)
HIS92_RS12675	COG2197	response regulator
HIS92_RS12680	COG4585	Histidine kinase
HIS92_RS12685	COG0842	Transport permease protein
HIS92_RS12690	COG1131	(ABC) transporter
HIS92_RS12695	COG0024	Methionine aminopeptidase
HIS92_RS12705	COG2234	aminopeptidase activity
HIS92_RS12725	COG1595	DNA-templated transcription, initiation
HIS92_RS12735	COG4506	Protein conserved in bacteria
HIS92_RS12740	COG1619	proteins homologs of microcin C7 resistance protein MccF
HIS92_RS12765	COG2814	Major facilitator Superfamily
HIS92_RS12770	COG0789	Transcriptional regulator
HIS92_RS12775	COG0584	glycerophosphoryl diester phosphodiesterase
HIS92_RS12780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HIS92_RS12790	COG1994	Peptidase M50
HIS92_RS12800	COG1078	dGTPase activity
HIS92_RS12805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HIS92_RS12810	COG1120	ATPase activity
HIS92_RS12815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIS92_RS12820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIS92_RS12840	COG0280	phosphate acetyltransferase
HIS92_RS12855	COG3773	Cell wall hydrolase
HIS92_RS12865	COG2363	Small membrane protein
HIS92_RS12875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HIS92_RS12880	COG2233	PERMEase
HIS92_RS12885	COG0561	phosphatase activity
HIS92_RS12890	COG2814	Major facilitator Superfamily
HIS92_RS12900	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HIS92_RS12905	COG1131	(ABC) transporter
HIS92_RS12910	COG2755	lipolytic protein G-D-S-L family
HIS92_RS12915	COG1609	Transcriptional regulator
HIS92_RS12925	COG0460	homoserine dehydrogenase
HIS92_RS12935	COG2873	o-acetylhomoserine
HIS92_RS12940	COG1011	Hydrolase
HIS92_RS12945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HIS92_RS12955	COG2197	response regulator
HIS92_RS12960	COG4585	Histidine kinase
HIS92_RS12960	COG2203	Gaf domain
HIS92_RS12965	COG0351	phosphomethylpyrimidine kinase
HIS92_RS12970	COG3706	GGDEF domain
HIS92_RS12975	COG2879	small protein
HIS92_RS12980	COG1966	Carbon starvation protein
HIS92_RS12985	COG3279	Response regulator of the LytR AlgR family
HIS92_RS12990	COG0477	Major facilitator Superfamily
HIS92_RS13000	COG0438	transferase activity, transferring glycosyl groups
HIS92_RS13015	COG0840	transmembrane signaling receptor activity
HIS92_RS13025	COG1607	acyl-coa hydrolase
HIS92_RS13030	COG1216	Glycosyl transferase, family 2
HIS92_RS13045	COG1216	Glycosyl transferase, family 2
HIS92_RS13055	COG4485	Bacterial membrane protein, YfhO
HIS92_RS13060	COG0463	Glycosyl transferase, family 2
HIS92_RS13070	COG1309	transcriptional regulator
HIS92_RS13075	COG0488	(ABC) transporter
HIS92_RS13080	COG1309	transcriptional regulator
HIS92_RS13085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HIS92_RS13090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIS92_RS13090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIS92_RS13095	COG0628	permease
HIS92_RS13115	COG3275	phosphorelay sensor kinase activity
HIS92_RS13120	COG2814	Major facilitator Superfamily
HIS92_RS13125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HIS92_RS13130	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HIS92_RS13155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HIS92_RS13160	COG1272	protein, Hemolysin III
HIS92_RS13180	COG1164	Oligoendopeptidase f
HIS92_RS13200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HIS92_RS13250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HIS92_RS13255	COG0322	excinuclease ABC activity
HIS92_RS13300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HIS92_RS13315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIS92_RS13320	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HIS92_RS13325	COG4853	Protein conserved in bacteria
HIS92_RS13335	COG5002	protein histidine kinase activity
HIS92_RS13340	COG0745	RESPONSE REGULATOR receiver
HIS92_RS13370	COG0305	Participates in initiation and elongation during chromosome replication
HIS92_RS13380	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HIS92_RS13385	COG4241	membrane
HIS92_RS13395	COG0629	single-stranded DNA binding
HIS92_RS13405	COG0012	GTP binding
HIS92_RS13410	COG4481	Protein conserved in bacteria
HIS92_RS13415	COG0668	transmembrane transport
HIS92_RS13425	COG1475	DNA binding
HIS92_RS13430	COG1192	Involved in chromosome partitioning
HIS92_RS13455	COG1847	R3H domain protein
HIS92_RS13470	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HIS92_RS13480	COG0592	DNA-directed DNA polymerase activity
HIS92_RS13485	COG2501	S4 domain
HIS92_RS13495	COG0187	DNA topoisomerase II activity
HIS92_RS13500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIS92_RS13535	COG0517	IMP dehydrogenase activity
HIS92_RS13535	COG0516	GMP reductase activity
HIS92_RS13540	COG1686	Belongs to the peptidase S11 family
HIS92_RS13570	COG1428	Deoxynucleoside kinase
HIS92_RS13575	COG1428	Deoxynucleoside kinase
HIS92_RS13580	COG1335	isochorismatase
HIS92_RS13585	COG0590	tRNA wobble adenosine to inosine editing
HIS92_RS13595	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIS92_RS13650	COG1982	Orn Lys Arg decarboxylase major
HIS92_RS13660	COG0470	DNA polymerase III
HIS92_RS13665	COG1774	PSP1 C-terminal conserved region
HIS92_RS13675	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HIS92_RS13685	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HIS92_RS13690	COG2002	toxin-antitoxin pair type II binding
HIS92_RS13700	COG0084	hydrolase, TatD family'
HIS92_RS13720	COG4466	Protein conserved in bacteria
HIS92_RS13735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HIS92_RS13740	COG0251	oxidation-reduction process
HIS92_RS13770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIS92_RS13775	COG2002	toxin-antitoxin pair type II binding
HIS92_RS13780	COG2244	polysaccharide biosynthetic process
HIS92_RS13785	COG3956	TIGRFAM MazG family protein
HIS92_RS13790	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HIS92_RS13810	COG1098	S1 RNA binding domain
HIS92_RS13825	COG2208	phosphoserine phosphatase activity
HIS92_RS13840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIS92_RS13855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HIS92_RS13860	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HIS92_RS13865	COG0512	Glutamine amidotransferase of anthranilate synthase
HIS92_RS13870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HIS92_RS13875	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HIS92_RS13880	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HIS92_RS13885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HIS92_RS13890	COG1396	sequence-specific DNA binding
HIS92_RS13895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIS92_RS13925	COG3880	PFAM UvrB UvrC protein
HIS92_RS13935	COG0542	response to heat
HIS92_RS13940	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HIS92_RS13950	COG4956	integral membrane protein (PIN domain superfamily)
HIS92_RS13970	COG1045	serine acetyltransferase
HIS92_RS13985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIS92_RS13990	COG3688	RNA-binding protein containing a PIN domain
HIS92_RS14005	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HIS92_RS14010	COG0250	Participates in transcription elongation, termination and antitermination
HIS92_RS14015	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HIS92_RS14035	COG2813	Specifically methylates the guanine in position
HIS92_RS14045	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIS92_RS14050	COG1358	cellular component organization or biogenesis
HIS92_RS14055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HIS92_RS14075	COG0051	transcription antitermination factor activity, RNA binding
HIS92_RS14080	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HIS92_RS14120	COG0255	Belongs to the universal ribosomal protein uL29 family
HIS92_RS14180	COG0201	protein transport
HIS92_RS14190	COG0024	Methionine aminopeptidase
HIS92_RS14200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HIS92_RS14235	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIS92_RS14260	COG0860	N-Acetylmuramoyl-L-alanine amidase
HIS92_RS14265	COG0489	protein tyrosine kinase activity
HIS92_RS14275	COG2194	sulfuric ester hydrolase activity
HIS92_RS14280	COG0726	polysaccharide deacetylase
HIS92_RS14360	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIS92_RS14365	COG4856	YbbR-like protein
HIS92_RS14400	COG1028	Short-chain dehydrogenase reductase Sdr
HIS92_RS14405	COG2011	ABC-type metal ion transport system permease component
HIS92_RS14410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIS92_RS14415	COG1464	Belongs to the NlpA lipoprotein family
HIS92_RS14420	COG0604	alcohol dehydrogenase
HIS92_RS14430	COG0277	FAD linked oxidase domain protein
HIS92_RS14435	COG2271	Major facilitator Superfamily
HIS92_RS14445	COG2814	Major facilitator Superfamily
HIS92_RS14465	COG0601	transmembrane transport
HIS92_RS14470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIS92_RS14475	COG0444	Belongs to the ABC transporter superfamily
HIS92_RS14480	COG4608	Belongs to the ABC transporter superfamily
HIS92_RS14485	COG4166	transmembrane transport
HIS92_RS14500	COG4166	transmembrane transport
HIS92_RS14505	COG4166	transmembrane transport
HIS92_RS14510	COG0656	L-ascorbic acid biosynthetic process
HIS92_RS14525	COG4149	molybdate abc transporter
HIS92_RS14530	COG0725	ABC transporter, periplasmic molybdate-binding protein
HIS92_RS14535	COG1910	domain protein
HIS92_RS14550	COG0697	spore germination
HIS92_RS14565	COG0204	Acyl-transferase
HIS92_RS14575	COG1609	Transcriptional regulator
HIS92_RS14585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIS92_RS14600	COG5298	Protein conserved in bacteria
HIS92_RS14620	COG0488	(ABC) transporter
HIS92_RS14630	COG0747	negative chemotaxis
HIS92_RS14635	COG0601	transmembrane transport
HIS92_RS14645	COG0444	Belongs to the ABC transporter superfamily
HIS92_RS14650	COG4608	Belongs to the ABC transporter superfamily
HIS92_RS14655	COG0561	phosphatase activity
HIS92_RS14680	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HIS92_RS14685	COG0179	Fumarylacetoacetate (FAA) hydrolase
HIS92_RS14695	COG0531	amino acid
HIS92_RS14700	COG2814	Major facilitator Superfamily
HIS92_RS14710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HIS92_RS14720	COG4294	response to UV
HIS92_RS14725	COG0705	Rhomboid family
HIS92_RS14735	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HIS92_RS14740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIS92_RS14745	COG0864	Transcriptional regulator
HIS92_RS14750	COG2337	Toxic component of a toxin-antitoxin (TA) module
HIS92_RS14755	COG2183	response to ionizing radiation
HIS92_RS14855	COG0802	atpase or kinase
HIS92_RS14860	COG1214	PFAM Peptidase M22, glycoprotease
HIS92_RS14865	COG0456	acetyltransferase
HIS92_RS14875	COG0488	(ABC) transporter
HIS92_RS14890	COG1266	CAAX protease self-immunity
HIS92_RS14905	COG0582	viral genome integration into host DNA
HIS92_RS15025	COG1674	ftsk spoiiie
HIS92_RS15035	COG2946	Replication initiation factor
HIS92_RS15050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HIS92_RS15060	COG2252	PERMEase
HIS92_RS15070	COG5002	protein histidine kinase activity
HIS92_RS15095	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HIS92_RS15135	COG2205	protein histidine kinase activity
HIS92_RS15140	COG0745	RESPONSE REGULATOR receiver
HIS92_RS15160	COG0697	spore germination
HIS92_RS15185	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HIS92_RS15190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HIS92_RS15195	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HIS92_RS15205	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIS92_RS15220	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HIS92_RS15230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HIS92_RS15240	COG0151	Belongs to the GarS family
HIS92_RS15265	COG0210	DNA helicase
HIS92_RS15275	COG4851	CamS sex pheromone cAM373 precursor
HIS92_RS15290	COG1335	isochorismatase
HIS92_RS15300	COG2011	ABC-type metal ion transport system permease component
HIS92_RS15305	COG1464	Belongs to the NlpA lipoprotein family
HIS92_RS15320	COG0003	Pfam Anion-transporting ATPase
HIS92_RS15325	COG1846	Transcriptional regulator
HIS92_RS15330	COG4682	membrane
HIS92_RS15350	COG1597	lipid kinase activity
HIS92_RS15355	COG0546	phosphoglycolate phosphatase activity
HIS92_RS15360	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIS92_RS15370	COG1012	belongs to the aldehyde dehydrogenase family
HIS92_RS15375	COG2076	Multidrug Resistance protein
HIS92_RS15385	COG2309	aminopeptidase activity
HIS92_RS15400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIS92_RS15410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIS92_RS15415	COG4807	Protein conserved in bacteria
HIS92_RS15445	COG1473	amidohydrolase
HIS92_RS15460	COG0450	alkyl hydroperoxide reductase
HIS92_RS15470	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HIS92_RS15485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIS92_RS15490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIS92_RS15495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HIS92_RS15510	COG0166	Belongs to the GPI family
HIS92_RS15535	COG5002	protein histidine kinase activity
HIS92_RS15555	COG3541	Predicted nucleotidyltransferase
HIS92_RS15560	COG2814	Major facilitator Superfamily
HIS92_RS15565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HIS92_RS15565	COG0723	plastoquinol--plastocyanin reductase activity
HIS92_RS15575	COG0765	amino acid transport
HIS92_RS15580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HIS92_RS15585	COG1126	abc transporter atp-binding protein
HIS92_RS15590	COG0840	transmembrane signaling receptor activity
HIS92_RS15615	COG0549	Belongs to the carbamate kinase family
HIS92_RS15620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HIS92_RS15630	COG0277	FAD linked oxidase domain protein
HIS92_RS15635	COG0366	Alpha amylase catalytic
HIS92_RS15640	COG2190	(PTS) system
HIS92_RS15640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HIS92_RS15640	COG1263	PTS System
HIS92_RS15670	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HIS92_RS15690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HIS92_RS15695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HIS92_RS15700	COG1116	anion transmembrane transporter activity
HIS92_RS15705	COG0488	(ABC) transporter
HIS92_RS15750	COG2270	Major facilitator Superfamily
HIS92_RS15780	COG2310	stress, protein
HIS92_RS15785	COG2310	stress, protein
HIS92_RS15790	COG2310	stress, protein
HIS92_RS15795	COG0861	Integral membrane protein TerC family
HIS92_RS15805	COG3853	Toxic anion resistance protein (TelA)
HIS92_RS15820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIS92_RS15830	COG1295	ribonuclease BN
HIS92_RS15835	COG2217	Heavy metal translocating P-type atpase
HIS92_RS15840	COG0697	spore germination
HIS92_RS15850	COG0681	Belongs to the peptidase S26 family
HIS92_RS15860	COG0586	Pfam SNARE associated Golgi protein
HIS92_RS15875	COG3871	stress protein (general stress protein 26)
HIS92_RS15880	COG0387	Pfam Sodium calcium exchanger
HIS92_RS15890	COG0535	radical SAM domain protein
HIS92_RS15910	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HIS92_RS15915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIS92_RS15935	COG3829	transcription factor binding
HIS92_RS15945	COG0833	amino acid
HIS92_RS15950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HIS92_RS15980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HIS92_RS15980	COG1263	PTS System
HIS92_RS15985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HIS92_RS16000	COG0463	Glycosyl transferase, family 2
HIS92_RS16010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HIS92_RS16010	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HIS92_RS16015	COG0463	Glycosyl transferase, family 2
HIS92_RS16030	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HIS92_RS16050	COG1228	amidohydrolase
HIS92_RS16055	COG1090	epimerase
HIS92_RS16085	COG1988	membrane-bound metal-dependent
HIS92_RS16090	COG1194	a g-specific adenine glycosylase
HIS92_RS16115	COG1132	(ABC) transporter
HIS92_RS16120	COG4129	membrane
HIS92_RS16125	COG0067	glutamate synthase
HIS92_RS16125	COG0070	glutamate synthase
HIS92_RS16125	COG0069	glutamate synthase activity
HIS92_RS16135	COG4555	ABC transporter
HIS92_RS16155	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HIS92_RS16160	COG0735	belongs to the Fur family
HIS92_RS16280	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HIS92_RS16305	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HIS92_RS16315	COG2766	serine protein kinase
HIS92_RS16330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HIS92_RS16340	COG1585	Membrane protein implicated in regulation of membrane protease activity
HIS92_RS16345	COG2268	Band 7 protein
HIS92_RS16355	COG3290	protein histidine kinase activity
HIS92_RS16360	COG4565	transcriptional regulatory protein
HIS92_RS16365	COG2851	Citrate transporter
HIS92_RS16390	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HIS92_RS16395	COG3842	ATPase activity
HIS92_RS16400	COG1175	transmembrane transport
HIS92_RS16405	COG0395	ABC-type sugar transport system, permease component
HIS92_RS16415	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HIS92_RS16420	COG0745	RESPONSE REGULATOR receiver
HIS92_RS16425	COG5002	protein histidine kinase activity
HIS92_RS16435	COG4990	cell redox homeostasis
HIS92_RS16445	COG3290	protein histidine kinase activity
HIS92_RS16450	COG4565	transcriptional regulatory protein
HIS92_RS16455	COG3493	citrate carrier protein
HIS92_RS16460	COG0281	malic enzyme
HIS92_RS16475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HIS92_RS16480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HIS92_RS16490	COG5002	protein histidine kinase activity
HIS92_RS16510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HIS92_RS16515	COG3383	formate dehydrogenase (NAD+) activity
HIS92_RS16520	COG2427	Protein of unknown function (DUF1641)
HIS92_RS16535	COG0531	amino acid
HIS92_RS16540	COG0640	Transcriptional regulator
HIS92_RS16545	COG2217	Heavy metal translocating P-type atpase
HIS92_RS16550	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIS92_RS16565	COG3227	Zinc metalloprotease (Elastase)
HIS92_RS16585	COG2720	vancomycin resistance protein
HIS92_RS16590	COG1316	TRANSCRIPTIONal
HIS92_RS16595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIS92_RS16600	COG0346	lactoylglutathione lyase activity
HIS92_RS16605	COG1253	flavin adenine dinucleotide binding
HIS92_RS16610	COG1027	Aspartate ammonia-lyase
HIS92_RS16615	COG1620	l-lactate permease
HIS92_RS16630	COG3104	oligopeptide transport
HIS92_RS16635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HIS92_RS16640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIS92_RS16645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIS92_RS16660	COG0156	8-amino-7-oxononanoate synthase activity
HIS92_RS16665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HIS92_RS16675	COG4548	von Willebrand factor, type A
HIS92_RS16680	COG0714	Associated with various cellular activities
HIS92_RS16700	COG0531	amino acid
HIS92_RS16705	COG2188	Transcriptional regulator
HIS92_RS16710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HIS92_RS16710	COG1263	PTS System
HIS92_RS16715	COG0366	Alpha amylase catalytic
HIS92_RS16730	COG0697	spore germination
HIS92_RS16735	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HIS92_RS16745	COG1115	amino acid carrier protein
HIS92_RS16750	COG1126	abc transporter atp-binding protein
HIS92_RS16755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HIS92_RS16760	COG0765	amino acid transport
HIS92_RS16765	COG0765	amino acid transport
HIS92_RS16770	COG0833	amino acid
HIS92_RS16785	COG1595	DNA-templated transcription, initiation
HIS92_RS16795	COG2378	regulation of single-species biofilm formation
HIS92_RS16800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HIS92_RS16805	COG5002	protein histidine kinase activity
HIS92_RS16830	COG0659	secondary active sulfate transmembrane transporter activity
HIS92_RS16845	COG2271	Major facilitator Superfamily
HIS92_RS16850	COG1846	Transcriptional regulator
HIS92_RS16855	COG0477	Major facilitator Superfamily
HIS92_RS16860	COG1609	Transcriptional regulator
HIS92_RS16865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIS92_RS16880	COG1172	Belongs to the binding-protein-dependent transport system permease family
HIS92_RS16885	COG1879	ABC-type sugar transport system periplasmic component
HIS92_RS16915	COG1063	alcohol dehydrogenase
HIS92_RS16965	COG0840	transmembrane signaling receptor activity
HIS92_RS16970	COG3583	domain protein
HIS92_RS16970	COG3584	3D domain protein
HIS92_RS16975	COG1476	TRANSCRIPTIONal
HIS92_RS16995	COG3104	oligopeptide transport
HIS92_RS17000	COG1114	Component of the transport system for branched-chain amino acids
HIS92_RS17015	COG1113	amino acid transport
HIS92_RS17020	COG2252	PERMEase
HIS92_RS17035	COG2153	protein acetylation
HIS92_RS17045	COG0569	domain protein
HIS92_RS17045	COG0475	glutathione-regulated potassium exporter activity
HIS92_RS17060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HIS92_RS17070	COG0833	amino acid
HIS92_RS17075	COG4990	cell redox homeostasis
HIS92_RS17090	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIS92_RS17095	COG0697	spore germination
HIS92_RS17100	COG0531	amino acid
HIS92_RS17115	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HIS92_RS17120	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HIS92_RS17125	COG1918	ferrous iron import across plasma membrane
HIS92_RS17125	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HIS92_RS17130	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HIS92_RS17135	COG0573	inorganic phosphate transmembrane transporter activity
HIS92_RS17140	COG0581	inorganic phosphate transmembrane transporter activity
HIS92_RS17150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HIS92_RS17270	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HIS92_RS17290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HIS92_RS17295	COG1116	anion transmembrane transporter activity
HIS92_RS17300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HIS92_RS17305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HIS92_RS17310	COG0352	thiamine-phosphate diphosphorylase activity
HIS92_RS17315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HIS92_RS17320	COG2104	thiamine diphosphate biosynthetic process
HIS92_RS17330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HIS92_RS17335	COG0351	phosphomethylpyrimidine kinase
HIS92_RS17375	COG2205	protein histidine kinase activity
HIS92_RS17380	COG2814	Major facilitator Superfamily
HIS92_RS17385	COG1846	Transcriptional regulator
HIS92_RS17400	COG2252	PERMEase
HIS92_RS17405	COG1028	Short-chain dehydrogenase reductase Sdr
HIS92_RS17465	COG0778	Nitroreductase
HIS92_RS17470	COG2719	SpoVR family
HIS92_RS17490	COG1937	Protein conserved in bacteria
HIS92_RS17495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIS92_RS17495	COG0425	Belongs to the sulfur carrier protein TusA family
HIS92_RS17500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIS92_RS17500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIS92_RS17505	COG0425	Belongs to the sulfur carrier protein TusA family
HIS92_RS17510	COG0425	Belongs to the sulfur carrier protein TusA family
HIS92_RS17510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIS92_RS17520	COG2210	Belongs to the sulfur carrier protein TusA family
HIS92_RS17525	COG0730	response to heat
HIS92_RS17535	COG1316	TRANSCRIPTIONal
HIS92_RS17540	COG0604	alcohol dehydrogenase
HIS92_RS17545	COG1283	sodium-dependent phosphate transmembrane transporter activity
HIS92_RS17560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HIS92_RS17560	COG3711	transcriptional antiterminator
HIS92_RS17565	COG1447	Phosphotransferase system cellobiose-specific component IIA
HIS92_RS17570	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HIS92_RS17595	COG1388	LysM domain
HIS92_RS17595	COG3584	3D domain protein
HIS92_RS17600	COG0577	efflux transmembrane transporter activity
HIS92_RS17605	COG1136	(ABC) transporter
HIS92_RS17615	COG5522	Integral membrane protein (intg_mem_TP0381)
HIS92_RS17630	COG1114	Component of the transport system for branched-chain amino acids
HIS92_RS17635	COG3546	catalase activity
HIS92_RS17670	COG0586	Pfam SNARE associated Golgi protein
HIS92_RS17705	COG0531	amino acid
HIS92_RS17710	COG0475	glutathione-regulated potassium exporter activity
HIS92_RS17720	COG1737	Transcriptional regulator
HIS92_RS17730	COG1263	PTS System
HIS92_RS17730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HIS92_RS17740	COG2259	Doxx family
HIS92_RS17760	COG1522	sequence-specific DNA binding
HIS92_RS17770	COG1028	Short-chain dehydrogenase reductase Sdr
HIS92_RS17775	COG0789	Transcriptional regulator
HIS92_RS17790	COG1309	transcriptional regulator
HIS92_RS17795	COG2814	Major facilitator Superfamily
HIS92_RS17800	COG1733	regulation of RNA biosynthetic process
HIS92_RS17820	COG0693	protein deglycase activity
HIS92_RS17825	COG0753	catalase activity
HIS92_RS17825	COG0693	protein deglycase activity
HIS92_RS17835	COG0531	amino acid
HIS92_RS17840	COG1012	belongs to the aldehyde dehydrogenase family
HIS92_RS17845	COG1132	(ABC) transporter
HIS92_RS17850	COG1132	(ABC) transporter
HIS92_RS17855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HIS92_RS17860	COG0765	amino acid transport
HIS92_RS17865	COG1126	abc transporter atp-binding protein
HIS92_RS17880	COG0189	ligase activity
HIS92_RS17910	COG0028	Belongs to the TPP enzyme family
HIS92_RS17915	COG3527	Alpha-acetolactate decarboxylase
HIS92_RS17930	COG0561	phosphatase activity
HIS92_RS17940	COG5632	N-Acetylmuramoyl-L-alanine amidase
HIS92_RS17940	COG3409	Peptidoglycan-binding domain 1 protein
HIS92_RS17945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HIS92_RS17950	COG0318	PFAM AMP-dependent synthetase and ligase
HIS92_RS17960	COG0659	secondary active sulfate transmembrane transporter activity
HIS92_RS17985	COG1024	Enoyl-CoA hydratase
HIS92_RS18005	COG1363	Peptidase, m42
HIS92_RS18040	COG0601	transmembrane transport
HIS92_RS18045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIS92_RS18050	COG0444	Belongs to the ABC transporter superfamily
HIS92_RS18055	COG4608	Belongs to the ABC transporter superfamily
HIS92_RS18065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HIS92_RS18085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HIS92_RS18100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HIS92_RS18105	COG2814	Major facilitator Superfamily
HIS92_RS18165	COG3157	Type VI secretion system effector, Hcp
HIS92_RS18220	COG0477	Major facilitator Superfamily
HIS92_RS18225	COG3290	protein histidine kinase activity
HIS92_RS18230	COG4565	transcriptional regulatory protein
HIS92_RS18235	COG3181	Tripartite tricarboxylate transporter family receptor
HIS92_RS18275	COG0210	DNA helicase
HIS92_RS18295	COG0305	Participates in initiation and elongation during chromosome replication
HIS92_RS18325	COG0477	Major facilitator Superfamily
HIS92_RS18410	COG1073	alpha beta
HIS92_RS18470	COG1183	phosphatidylcholine synthase activity
HIS92_RS18480	COG2814	Major facilitator Superfamily
HIS92_RS18485	COG0640	Transcriptional regulator
HIS92_RS18495	COG2376	Dihydroxyacetone kinase
HIS92_RS18505	COG2376	Dihydroxyacetone kinase
HIS92_RS18565	COG2373	Large extracellular alpha-helical protein
HIS92_RS18640	COG1191	sigma factor activity
HIS92_RS18650	COG2208	phosphoserine phosphatase activity
HIS92_RS18655	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HIS92_RS18710	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HIS92_RS18730	COG0420	3'-5' exonuclease activity
HIS92_RS18735	COG4717	serine-type aminopeptidase activity
HIS92_RS18750	COG1280	lysine exporter protein (LysE YggA)
HIS92_RS18755	COG0346	lactoylglutathione lyase activity
HIS92_RS18760	COG0346	lactoylglutathione lyase activity
HIS92_RS18775	COG2267	carboxylic ester hydrolase activity
HIS92_RS18800	COG2140	Oxalate decarboxylase
HIS92_RS18805	COG3620	sequence-specific DNA binding
HIS92_RS18815	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HIS92_RS18820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HIS92_RS18830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HIS92_RS18835	COG1695	Transcriptional regulator
HIS92_RS18865	COG3973	AAA domain
HIS92_RS18890	COG4980	gas vesicle protein
HIS92_RS18895	COG0537	adenosine 5'-monophosphoramidase activity
HIS92_RS18900	COG1131	(ABC) transporter
HIS92_RS18905	COG4473	ABC transporter
HIS92_RS18920	COG1309	transcriptional regulator
HIS92_RS18930	COG3402	PFAM membrane-flanked domain
HIS92_RS18935	COG3428	Bacterial PH domain
HIS92_RS18970	COG0697	spore germination
HIS92_RS18975	COG3402	PFAM membrane-flanked domain
HIS92_RS18985	COG2329	Antibiotic biosynthesis monooxygenase
HIS92_RS18990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HIS92_RS19030	COG1309	transcriptional regulator
HIS92_RS19035	COG1511	domain protein
HIS92_RS19060	COG1609	Transcriptional regulator
HIS92_RS19070	COG1234	tRNA 3'-trailer cleavage
HIS92_RS19075	COG0095	Lipoate-protein ligase
HIS92_RS19085	COG0318	PFAM AMP-dependent synthetase and ligase
HIS92_RS19145	COG1073	alpha beta
HIS92_RS19150	COG1408	metallophosphoesterase
HIS92_RS19155	COG1078	dGTPase activity
HIS92_RS19165	COG1595	DNA-templated transcription, initiation
HIS92_RS19170	COG2207	Transcriptional regulator
HIS92_RS19170	COG3708	Transcriptional regulator
HIS92_RS19180	COG2205	protein histidine kinase activity
HIS92_RS19185	COG0745	RESPONSE REGULATOR receiver
HIS92_RS19205	COG0501	Belongs to the peptidase M48B family
HIS92_RS19210	COG0840	transmembrane signaling receptor activity
HIS92_RS19220	COG3693	PFAM glycoside hydrolase, family 10
HIS92_RS19230	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HIS92_RS19235	COG2224	Isocitrate lyase
HIS92_RS19250	COG1278	Cold shock
HIS92_RS19265	COG4903	ComK protein
HIS92_RS19270	COG0398	Pfam SNARE associated Golgi protein
HIS92_RS19330	COG0179	Fumarylacetoacetate (FAA) hydrolase
HIS92_RS19355	COG0367	asparagine synthase
HIS92_RS19365	COG0753	catalase activity
HIS92_RS19370	COG0004	ammonium transporteR
HIS92_RS19390	COG2996	Protein conserved in bacteria
HIS92_RS19395	COG3209	COG3209 Rhs family protein
HIS92_RS19450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIS92_RS19465	COG0561	phosphatase activity
HIS92_RS19485	COG2267	carboxylic ester hydrolase activity
HIS92_RS19500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HIS92_RS19505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HIS92_RS19510	COG5504	Zn-dependent protease
HIS92_RS19520	COG0180	Tryptophanyl-tRNA synthetase
HIS92_RS19530	COG4166	transmembrane transport
HIS92_RS19535	COG0601	transmembrane transport
HIS92_RS19540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIS92_RS19545	COG0444	Belongs to the ABC transporter superfamily
HIS92_RS19550	COG4608	Belongs to the ABC transporter superfamily
HIS92_RS19555	COG0534	Mate efflux family protein
HIS92_RS19560	COG4166	transmembrane transport
HIS92_RS19575	COG0861	Integral membrane protein TerC family
HIS92_RS19585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIS92_RS19595	COG1164	Oligoendopeptidase f
HIS92_RS19610	COG2346	COG2346, Truncated hemoglobins
HIS92_RS19615	COG4116	CYTH
HIS92_RS19625	COG2357	RelA SpoT domain protein
HIS92_RS19635	COG0564	pseudouridine synthase activity
HIS92_RS19650	COG0772	Belongs to the SEDS family
HIS92_RS19655	COG1216	Glycosyl transferase, family 2
HIS92_RS19695	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HIS92_RS19710	COG1091	dTDP-4-dehydrorhamnose reductase activity
HIS92_RS19755	COG2153	protein acetylation
HIS92_RS19765	COG2382	esterase
HIS92_RS19780	COG5492	domain, Protein
HIS92_RS19785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIS92_RS19795	COG0512	Glutamine amidotransferase of anthranilate synthase
HIS92_RS19795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HIS92_RS19830	COG1620	l-lactate permease
HIS92_RS19835	COG5634	Uncharacterized conserved protein (DUF2278)
HIS92_RS19890	COG0508	dehydrogenase complex catalyzes the overall conversion of
HIS92_RS19900	COG1476	TRANSCRIPTIONal
HIS92_RS19930	COG4152	abc transporter atp-binding protein
HIS92_RS19935	COG1668	transmembrane transport
HIS92_RS19960	COG2226	methyltransferase
HIS92_RS19970	COG1686	Belongs to the peptidase S11 family
HIS92_RS19975	COG0681	Belongs to the peptidase S26 family
HIS92_RS20010	COG1012	belongs to the aldehyde dehydrogenase family
HIS92_RS20020	COG1176	ABC-type spermidine putrescine transport system, permease component I
HIS92_RS20025	COG1177	transmembrane transport
HIS92_RS20035	COG0671	phosphoesterase, PA-phosphatase related
HIS92_RS20040	COG2409	Drug exporters of the RND superfamily
HIS92_RS20050	COG0564	pseudouridine synthase activity
HIS92_RS20060	COG2340	Cysteine-rich secretory protein family
HIS92_RS20065	COG0247	lactate metabolic process
HIS92_RS20070	COG0277	FAD linked oxidase domain protein
HIS92_RS20075	COG3835	regulator
HIS92_RS20085	COG0745	RESPONSE REGULATOR receiver
HIS92_RS20090	COG5002	protein histidine kinase activity
HIS92_RS20095	COG2186	Transcriptional regulator
HIS92_RS20115	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HIS92_RS20125	COG2116	formate transmembrane transporter activity
HIS92_RS20130	COG0861	Integral membrane protein TerC family
HIS92_RS20135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HIS92_RS20145	COG2030	dehydratase
HIS92_RS20165	COG1028	Short-chain dehydrogenase reductase Sdr
HIS92_RS20170	COG3243	poly(R)-hydroxyalkanoic acid synthase
HIS92_RS20180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HIS92_RS20195	COG1840	ABC-type Fe3 transport system, periplasmic component
HIS92_RS20200	COG3842	ATPase activity
HIS92_RS20225	COG1349	DNA-binding transcription factor activity
HIS92_RS20235	COG0235	Class ii aldolase
HIS92_RS20245	COG2861	carbohydrate metabolic process
HIS92_RS20255	COG3852	Histidine kinase
HIS92_RS20260	COG1846	Transcriptional regulator
HIS92_RS20270	COG2318	DinB family
HIS92_RS20275	COG5002	protein histidine kinase activity
HIS92_RS20285	COG0720	synthase
HIS92_RS20300	COG4873	Protein conserved in bacteria
HIS92_RS20330	COG1780	Probably involved in ribonucleotide reductase function
HIS92_RS20335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIS92_RS20340	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIS92_RS20345	COG1725	Transcriptional regulator
HIS92_RS20350	COG1131	(ABC) transporter
HIS92_RS20360	COG1131	(ABC) transporter
HIS92_RS20380	COG1522	sequence-specific DNA binding
HIS92_RS20390	COG1335	isochorismatase
HIS92_RS20400	COG1619	proteins homologs of microcin C7 resistance protein MccF
HIS92_RS20405	COG2070	2-Nitropropane dioxygenase
HIS92_RS20410	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HIS92_RS20420	COG1696	Membrane protein involved in D-alanine export
HIS92_RS20445	COG0716	FMN binding
HIS92_RS20500	COG1846	Transcriptional regulator
HIS92_RS20510	COG1301	dicarboxylic acid transport
HIS92_RS20515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HIS92_RS20520	COG4709	membrane
HIS92_RS20525	COG3874	Sporulation protein YtfJ
HIS92_RS20545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HIS92_RS20550	COG0028	Belongs to the TPP enzyme family
HIS92_RS20555	COG0440	acetolactate synthase activity
HIS92_RS20630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HIS92_RS20645	COG1183	phosphatidylcholine synthase activity
HIS92_RS20650	COG1368	sulfuric ester hydrolase activity
HIS92_RS20660	COG0019	diaminopimelate decarboxylase activity
HIS92_RS20680	COG0529	Catalyzes the synthesis of activated sulfate
HIS92_RS20685	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HIS92_RS20705	COG1648	precorrin-2 dehydrogenase activity
HIS92_RS20710	COG0733	neurotransmitter:sodium symporter activity
HIS92_RS20735	COG1757	Na H antiporter
HIS92_RS20750	COG4758	membrane
HIS92_RS20755	COG4585	Histidine kinase
HIS92_RS20760	COG2197	response regulator
HIS92_RS20770	COG1114	Component of the transport system for branched-chain amino acids
HIS92_RS20820	COG0730	response to heat
HIS92_RS20825	COG0306	phosphate transporter
HIS92_RS20830	COG1392	Phosphate transport regulator
HIS92_RS20835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HIS92_RS20850	COG3852	Histidine kinase
HIS92_RS20855	COG1801	Protein of unknown function DUF72
HIS92_RS20865	COG0582	viral genome integration into host DNA
HIS92_RS20870	COG5002	protein histidine kinase activity
HIS92_RS20885	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HIS92_RS20885	COG0392	lysyltransferase activity
HIS92_RS20900	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HIS92_RS20905	COG1686	Belongs to the peptidase S11 family
HIS92_RS20910	COG2715	membrane protein required for spore maturation
HIS92_RS20915	COG0700	Nucleoside recognition
HIS92_RS20920	COG1187	pseudouridine synthase activity
HIS92_RS20930	COG1333	cytochrome c biogenesis protein
HIS92_RS20935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HIS92_RS20940	COG0745	RESPONSE REGULATOR receiver
HIS92_RS20945	COG5002	protein histidine kinase activity
HIS92_RS20950	COG2096	Adenosyltransferase
HIS92_RS20955	COG4942	peptidase
HIS92_RS20965	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HIS92_RS20970	COG1141	Ferredoxin
HIS92_RS20980	COG0514	ATP-dependent DNA helicase (RecQ)
HIS92_RS20985	COG1266	CAAX protease self-immunity
HIS92_RS20995	COG1408	metallophosphoesterase
HIS92_RS21000	COG0789	Transcriptional regulator
HIS92_RS21010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HIS92_RS21030	COG0492	ferredoxin-NADP+ reductase activity
HIS92_RS21035	COG0252	asparaginase activity
HIS92_RS21105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HIS92_RS21120	COG0142	geranyltranstransferase activity
HIS92_RS21130	COG0142	geranyltranstransferase activity
HIS92_RS21155	COG0457	Tetratricopeptide repeat
HIS92_RS21175	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HIS92_RS21180	COG2010	Cytochrome c
HIS92_RS21180	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HIS92_RS21185	COG4347	Protein of unknown function (DUF1405)
HIS92_RS21200	COG2738	Putative neutral zinc metallopeptidase
HIS92_RS21210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIS92_RS21215	COG1694	Mazg nucleotide pyrophosphohydrolase
HIS92_RS21235	COG0438	transferase activity, transferring glycosyl groups
HIS92_RS21270	COG1199	ATP-dependent helicase activity
HIS92_RS21270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HIS92_RS21290	COG3935	DnaD domain protein
HIS92_RS21295	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HIS92_RS21305	COG4499	WXG100 protein secretion system (Wss), protein YukC
HIS92_RS21305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HIS92_RS21360	COG0116	Belongs to the methyltransferase superfamily
HIS92_RS21370	COG1199	ATP-dependent helicase activity
HIS92_RS21375	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HIS92_RS21385	COG3173	Aminoglycoside phosphotransferase
HIS92_RS21390	COG0024	Methionine aminopeptidase
HIS92_RS21400	COG2233	PERMEase
HIS92_RS21405	COG2311	Membrane
HIS92_RS21415	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HIS92_RS21425	COG0456	acetyltransferase
HIS92_RS21460	COG0754	glutathionylspermidine amidase activity
HIS92_RS21475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIS92_RS21490	COG3944	biosynthesis protein
HIS92_RS21500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HIS92_RS21515	COG1215	transferase activity, transferring glycosyl groups
HIS92_RS21520	COG0438	transferase activity, transferring glycosyl groups
HIS92_RS21535	COG0454	-acetyltransferase
HIS92_RS21555	COG0328	RNA-DNA hybrid ribonuclease activity
HIS92_RS21590	COG3403	YqcI/YcgG family
HIS92_RS21595	COG1280	lysine exporter protein (LysE YggA)
HIS92_RS21615	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIS92_RS21620	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HIS92_RS21630	COG0475	glutathione-regulated potassium exporter activity
HIS92_RS21640	COG0789	Transcriptional regulator
HIS92_RS21640	COG4978	Transcriptional regulator
HIS92_RS21650	COG2323	membrane
HIS92_RS21655	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HIS92_RS21695	COG1923	regulation of RNA biosynthetic process
HIS92_RS21705	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HIS92_RS21710	COG1360	Flagellar Motor Protein
HIS92_RS21715	COG2201	protein-glutamate methylesterase activity
HIS92_RS21720	COG0643	Histidine kinase
HIS92_RS21720	COG2198	Histidine kinase
HIS92_RS21725	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HIS92_RS21725	COG1776	CheC inhibitor of MCP methylation
HIS92_RS21740	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HIS92_RS21760	COG1256	bacterial-type flagellum assembly
HIS92_RS21765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HIS92_RS21785	COG1815	bacterial-type flagellum-dependent cell motility
HIS92_RS21790	COG1558	bacterial-type flagellum-dependent cell motility
HIS92_RS21800	COG1766	The M ring may be actively involved in energy transduction
HIS92_RS21805	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HIS92_RS21815	COG1157	protein secretion by the type III secretion system
HIS92_RS21835	COG1749	Flagellar hook protein flgE
HIS92_RS21850	COG0784	Response regulator, receiver
HIS92_RS21850	COG0835	chemotaxis
HIS92_RS21870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HIS92_RS21875	COG0741	lytic transglycosylase activity
HIS92_RS21885	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HIS92_RS21890	COG1776	CheC inhibitor of MCP methylation
HIS92_RS21890	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HIS92_RS21900	COG1338	Plays a role in the flagellum-specific transport system
HIS92_RS21905	COG1987	bacterial-type flagellum assembly
HIS92_RS21915	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HIS92_RS21920	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HIS92_RS21925	COG1419	protein localization to endoplasmic reticulum
HIS92_RS21930	COG4786	Flagellar basal body rod
HIS92_RS21935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIS92_RS21940	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HIS92_RS21970	COG2329	Antibiotic biosynthesis monooxygenase
HIS92_RS21975	COG1215	transferase activity, transferring glycosyl groups
HIS92_RS22000	COG0583	DNA-binding transcription factor activity
HIS92_RS22020	COG1234	tRNA 3'-trailer cleavage
HIS92_RS22055	COG0406	alpha-ribazole phosphatase activity
HIS92_RS22075	COG1846	Transcriptional regulator
HIS92_RS22085	COG0367	asparagine synthase
HIS92_RS22125	COG0523	cobalamin synthesis protein
HIS92_RS22130	COG0701	Predicted permease
HIS92_RS22140	COG1216	Glycosyl transferase, family 2
HIS92_RS22140	COG0438	transferase activity, transferring glycosyl groups
HIS92_RS22145	COG1757	Na H antiporter
HIS92_RS22150	COG0789	Transcriptional regulator
HIS92_RS22180	COG0534	Mate efflux family protein
HIS92_RS22185	COG3340	Belongs to the peptidase S51 family
HIS92_RS22205	COG0785	Cytochrome C biogenesis protein
HIS92_RS22210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HIS92_RS22225	COG0457	Tetratricopeptide repeat
HIS92_RS22245	COG2733	membrane
HIS92_RS22280	COG1131	(ABC) transporter
HIS92_RS22295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIS92_RS22300	COG0528	UMP kinase activity
HIS92_RS22310	COG1027	Aspartate ammonia-lyase
HIS92_RS22315	COG0281	malic enzyme
HIS92_RS22320	COG4191	Histidine kinase
HIS92_RS22325	COG0784	Response regulator, receiver
HIS92_RS22330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HIS92_RS22375	COG2814	Major facilitator Superfamily
HIS92_RS22390	COG1695	Transcriptional regulator
HIS92_RS22400	COG0477	Major facilitator Superfamily
HIS92_RS22410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIS92_RS22415	COG2223	nitrite transmembrane transporter activity
HIS92_RS22420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HIS92_RS22440	COG0733	neurotransmitter:sodium symporter activity
HIS92_RS22450	COG5566	PFAM Mor transcription activator
HIS92_RS22455	COG2323	membrane
HIS92_RS22475	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIS92_RS22485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HIS92_RS22490	COG0028	Belongs to the TPP enzyme family
HIS92_RS22510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HIS92_RS22535	COG2814	Major facilitator Superfamily
HIS92_RS22540	COG3384	dioxygenase
HIS92_RS22555	COG3279	Response regulator of the LytR AlgR family
HIS92_RS22560	COG0427	acetyl-CoA hydrolase
HIS92_RS22580	COG4166	transmembrane transport
HIS92_RS22585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HIS92_RS22605	COG1914	H( )-stimulated, divalent metal cation uptake system
HIS92_RS22620	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIS92_RS22625	COG0531	amino acid
HIS92_RS22645	COG2309	aminopeptidase activity
HIS92_RS22660	COG0456	acetyltransferase
HIS92_RS22675	COG1309	transcriptional regulator
HIS92_RS22680	COG2390	Transcriptional regulator
HIS92_RS22690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIS92_RS22695	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HIS92_RS22700	COG0295	cytidine deaminase activity
HIS92_RS22735	COG4846	Membrane protein involved in cytochrome C biogenesis
HIS92_RS22745	COG0006	proline dipeptidase activity
HIS92_RS22755	COG2132	Multicopper oxidase
HIS92_RS22785	COG1114	Component of the transport system for branched-chain amino acids
HIS92_RS22795	COG2372	response to copper ion
HIS92_RS22795	COG1276	copper resistance
HIS92_RS22800	COG4549	nuclear export factor GLE1
HIS92_RS22805	COG0697	spore germination
HIS92_RS22810	COG0583	DNA-binding transcription factor activity
HIS92_RS22815	COG1959	2 iron, 2 sulfur cluster binding
HIS92_RS22820	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HIS92_RS22825	COG0778	Nitroreductase
HIS92_RS22835	COG0628	permease
HIS92_RS22845	COG1231	oxidoreductase activity
HIS92_RS22850	COG0523	cobalamin synthesis protein
HIS92_RS22860	COG0411	ABC transporter
HIS92_RS22880	COG0583	DNA-binding transcription factor activity
HIS92_RS22910	COG1271	oxidase subunit
HIS92_RS22915	COG1294	oxidase, subunit
HIS92_RS22920	COG4988	ABC transporter
HIS92_RS22925	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HIS92_RS22935	COG1216	Glycosyl transferase, family 2
HIS92_RS22975	COG1686	Belongs to the peptidase S11 family
HIS92_RS22990	COG1388	LysM domain
HIS92_RS22990	COG0791	NLP P60 protein
HIS92_RS23000	COG1132	(ABC) transporter
HIS92_RS23005	COG0745	RESPONSE REGULATOR receiver
HIS92_RS23010	COG5002	protein histidine kinase activity
HIS92_RS23015	COG0300	oxidoreductase activity
HIS92_RS23025	COG4122	O-methyltransferase activity
HIS92_RS23055	COG0460	homoserine dehydrogenase
HIS92_RS23080	COG1316	TRANSCRIPTIONal
HIS92_RS23095	COG1285	pathogenesis
HIS92_RS23100	COG1247	-acetyltransferase
HIS92_RS23110	COG4264	IucA IucC family
HIS92_RS23115	COG0318	PFAM AMP-dependent synthetase and ligase
HIS92_RS23130	COG1082	Xylose isomerase domain protein TIM barrel
HIS92_RS23140	COG2814	Major facilitator Superfamily
HIS92_RS23145	COG1279	arginine transmembrane transporter activity
HIS92_RS23150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HIS92_RS23160	COG1752	Esterase of the alpha-beta hydrolase superfamily
HIS92_RS23200	COG2002	toxin-antitoxin pair type II binding
HIS92_RS23205	COG1404	Belongs to the peptidase S8 family
HIS92_RS23210	COG0640	Transcriptional regulator
HIS92_RS23215	COG0667	Aldo Keto reductase
HIS92_RS23245	COG0840	transmembrane signaling receptor activity
HIS92_RS23260	COG3949	Membrane
HIS92_RS23265	COG0783	Belongs to the Dps family
HIS92_RS23280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIS92_RS23290	COG1231	oxidoreductase activity
HIS92_RS23295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HIS92_RS23300	COG4989	oxidoreductase activity
HIS92_RS23305	COG0523	cobalamin synthesis protein
HIS92_RS23310	COG0456	acetyltransferase
HIS92_RS23315	COG0803	Belongs to the bacterial solute-binding protein 9 family
HIS92_RS23325	COG0702	epimerase
HIS92_RS23335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIS92_RS23345	COG4166	transmembrane transport
HIS92_RS23360	COG0406	alpha-ribazole phosphatase activity
HIS92_RS23370	COG5337	Spore coat protein CotH
HIS92_RS23375	COG1051	belongs to the nudix hydrolase family
HIS92_RS23380	COG0586	Pfam SNARE associated Golgi protein
HIS92_RS23385	COG2244	polysaccharide biosynthetic process
HIS92_RS23395	COG0701	Predicted permease
HIS92_RS23400	COG3689	TIGRFAM TIGR03943 family protein
HIS92_RS23405	COG1607	acyl-coa hydrolase
HIS92_RS23415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIS92_RS23430	COG0702	epimerase
HIS92_RS23435	COG2839	Protein conserved in bacteria
HIS92_RS23440	COG1253	flavin adenine dinucleotide binding
HIS92_RS23465	COG1114	Component of the transport system for branched-chain amino acids
HIS92_RS23470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIS92_RS23490	COG0860	N-Acetylmuramoyl-L-alanine amidase
HIS92_RS23500	COG1876	peptidase activity
HIS92_RS23515	COG2211	Major facilitator Superfamily
HIS92_RS23530	COG0860	N-Acetylmuramoyl-L-alanine amidase
HIS92_RS23540	COG0561	phosphatase activity
HIS92_RS23545	COG1846	Transcriptional regulator
HIS92_RS23550	COG2814	Major facilitator Superfamily
HIS92_RS23560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIS92_RS23565	COG4106	trans-aconitate 2-methyltransferase activity
HIS92_RS23580	COG1819	glycosyl
HIS92_RS23585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIS92_RS23590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HIS92_RS23620	COG0456	acetyltransferase
HIS92_RS23775	COG4974	Belongs to the 'phage' integrase family
HIS92_RS23785	COG3874	Sporulation protein YtfJ
HIS92_RS23810	COG2226	methyltransferase
HIS92_RS23830	COG1082	Xylose isomerase domain protein TIM barrel
HIS92_RS23835	COG0346	lactoylglutathione lyase activity
HIS92_RS23845	COG0604	alcohol dehydrogenase
HIS92_RS23850	COG1595	DNA-templated transcription, initiation
HIS92_RS23860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HIS92_RS23870	COG0426	domain, Protein
HIS92_RS23870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HIS92_RS23880	COG0386	Belongs to the glutathione peroxidase family
HIS92_RS23885	COG1305	Transglutaminase-like
HIS92_RS23890	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
HIS92_RS23895	COG0714	Associated with various cellular activities
HIS92_RS23900	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HIS92_RS23905	COG1140	nitrate reductase beta subunit
HIS92_RS23910	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HIS92_RS23915	COG2181	nitrate reductase activity
HIS92_RS23920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HIS92_RS23925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HIS92_RS23930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HIS92_RS23935	COG0303	'Molybdopterin
HIS92_RS23940	COG0314	molybdopterin synthase activity
HIS92_RS23950	COG2223	nitrite transmembrane transporter activity
HIS92_RS23965	COG1648	precorrin-2 dehydrogenase activity
HIS92_RS23970	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
HIS92_RS23975	COG1587	Uroporphyrinogen-III synthase
HIS92_RS23975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HIS92_RS23980	COG2146	nitrite reductase [NAD(P)H] activity
HIS92_RS23985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HIS92_RS23990	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
HIS92_RS24025	COG2359	stage V sporulation protein S
HIS92_RS24045	COG0457	Tetratricopeptide repeat
HIS92_RS24060	COG1418	mRNA catabolic process
HIS92_RS24065	COG0488	(ABC) transporter
HIS92_RS24080	COG0629	single-stranded DNA binding
HIS92_RS24090	COG1413	lyase activity
HIS92_RS24105	COG2521	methyltransferase
HIS92_RS24105	COG2136	Putative SAM-dependent methyltransferase
HIS92_RS24110	COG0018	arginyl-trna synthetase
HIS92_RS24150	COG0017	Asparaginyl-tRNA synthetase
HIS92_RS24155	COG0733	neurotransmitter:sodium symporter activity
HIS92_RS24180	COG2610	gluconate transmembrane transporter activity
HIS92_RS24190	COG1794	racemase activity, acting on amino acids and derivatives
HIS92_RS24200	COG0456	acetyltransferase
HIS92_RS24210	COG3655	Transcriptional regulator
HIS92_RS24215	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HIS92_RS24225	COG1131	(ABC) transporter
HIS92_RS24240	COG0546	phosphoglycolate phosphatase activity
HIS92_RS24270	COG0768	penicillin binding
HIS92_RS24280	COG0204	Acyl-transferase
HIS92_RS24285	COG1272	protein, Hemolysin III
HIS92_RS24295	COG0805	protein transport
HIS92_RS24305	COG1307	EDD domain protein, DegV family
HIS92_RS24315	COG1999	signal sequence binding
HIS92_RS24320	COG0071	Belongs to the small heat shock protein (HSP20) family
HIS92_RS24325	COG0367	asparagine synthase
HIS92_RS24340	COG0860	N-Acetylmuramoyl-L-alanine amidase
HIS92_RS24345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HIS92_RS24350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HIS92_RS24365	COG1335	isochorismatase
HIS92_RS24370	COG1051	belongs to the nudix hydrolase family
HIS92_RS24375	COG0668	transmembrane transport
HIS92_RS24380	COG2203	Gaf domain
HIS92_RS24380	COG4585	Histidine kinase
HIS92_RS24385	COG2197	response regulator
HIS92_RS24390	COG1737	Transcriptional regulator
HIS92_RS24395	COG0384	phenazine biosynthesis protein PhzF
HIS92_RS24400	COG1064	alcohol dehydrogenase
HIS92_RS24415	COG1070	Carbohydrate kinase
HIS92_RS24425	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HIS92_RS24460	COG0517	IMP dehydrogenase activity
HIS92_RS24460	COG1125	glycine betaine transport
HIS92_RS24465	COG1174	glycine betaine transport
HIS92_RS24500	COG1253	flavin adenine dinucleotide binding
HIS92_RS24505	COG1012	belongs to the aldehyde dehydrogenase family
HIS92_RS24510	COG5506	Protein of unknown function (DUF1694)
HIS92_RS24525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HIS92_RS24530	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HIS92_RS24535	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HIS92_RS24540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HIS92_RS24545	COG0456	acetyltransferase
HIS92_RS24550	COG3829	transcription factor binding
HIS92_RS24555	COG1509	lysine 2,3-aminomutase activity
HIS92_RS24590	COG4991	sh3 domain protein
HIS92_RS24590	COG0515	serine threonine protein kinase
HIS92_RS24590	COG3064	Membrane
HIS92_RS24600	COG0671	phosphoesterase, PA-phosphatase related
HIS92_RS24605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIS92_RS24610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HIS92_RS24685	COG0300	oxidoreductase activity
HIS92_RS24705	COG4499	WXG100 protein secretion system (Wss), protein YukC
HIS92_RS24705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HIS92_RS24715	COG2814	Major facilitator Superfamily
HIS92_RS24720	COG4841	protein insertion into membrane
HIS92_RS24725	COG0372	Belongs to the citrate synthase family
HIS92_RS24730	COG2079	MmgE PrpD family protein
HIS92_RS24735	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HIS92_RS24740	COG1960	acyl-CoA dehydrogenase activity
HIS92_RS24745	COG2084	Dehydrogenase
HIS92_RS24755	COG1280	lysine exporter protein (LysE YggA)
HIS92_RS24760	COG1024	Enoyl-CoA hydratase
HIS92_RS24775	COG0420	3'-5' exonuclease activity
HIS92_RS24780	COG0419	ATPase involved in DNA repair
HIS92_RS24800	COG2223	nitrite transmembrane transporter activity
HIS92_RS24805	COG1028	Short-chain dehydrogenase reductase Sdr
HIS92_RS24810	COG1169	isochorismate synthase
HIS92_RS24815	COG1021	2,3-dihydroxybenzoate-AMP ligase
HIS92_RS24820	COG3433	isochorismatase activity
HIS92_RS24820	COG1535	isochorismatase
HIS92_RS24825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HIS92_RS24830	COG3251	PFAM MbtH domain protein
HIS92_RS24835	COG2814	Major facilitator Superfamily
HIS92_RS24850	COG0776	regulation of translation
HIS92_RS24860	COG2318	DinB family
HIS92_RS24870	COG1115	amino acid carrier protein
HIS92_RS24890	COG1187	pseudouridine synthase activity
HIS92_RS24895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIS92_RS24900	COG1136	(ABC) transporter
HIS92_RS25000	COG4474	Belongs to the UPF0398 family
HIS92_RS25040	COG0457	Tetratricopeptide repeat
HIS92_RS25100	COG5632	N-Acetylmuramoyl-L-alanine amidase
HIS92_RS25100	COG3409	Peptidoglycan-binding domain 1 protein
HIS92_RS25100	COG1388	LysM domain
HIS92_RS25215	COG0629	single-stranded DNA binding
HIS92_RS25225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HIS92_RS25260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIS92_RS25265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HIS92_RS25290	COG0756	dUTP diphosphatase activity
HIS92_RS25295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HIS92_RS25335	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HIS92_RS25340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HIS92_RS25355	COG5002	protein histidine kinase activity
HIS92_RS25360	COG5002	protein histidine kinase activity
HIS92_RS25380	COG1428	Deoxynucleoside kinase
HIS92_RS25505	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HIS92_RS25565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIS92_RS25590	COG2310	stress, protein
HIS92_RS25595	COG2310	stress, protein
HIS92_RS25605	COG0861	Integral membrane protein TerC family
HIS92_RS25615	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HIS92_RS25625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIS92_RS25630	COG1404	Belongs to the peptidase S8 family
HIS92_RS25650	COG4974	Belongs to the 'phage' integrase family
HIS92_RS25655	COG1780	Probably involved in ribonucleotide reductase function
HIS92_RS25660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIS92_RS25665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIS92_RS26165	COG0617	tRNA 3'-terminal CCA addition
HIS92_RS26195	COG2088	sporulation resulting in formation of a cellular spore
HIS92_RS26220	COG1393	Belongs to the ArsC family