locus-tag	class	description
BTK_RS00010	COG0592	DNA-directed DNA polymerase activity
BTK_RS00015	COG2501	S4 domain
BTK_RS00025	COG0187	DNA topoisomerase II activity
BTK_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTK_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTK_RS00040	COG0187	DNA topoisomerase II activity
BTK_RS00045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTK_RS00080	COG0516	GMP reductase activity
BTK_RS00080	COG0517	IMP dehydrogenase activity
BTK_RS00115	COG1428	Deoxynucleoside kinase
BTK_RS00120	COG1428	Deoxynucleoside kinase
BTK_RS00125	COG1335	isochorismatase
BTK_RS00135	COG0590	tRNA wobble adenosine to inosine editing
BTK_RS00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTK_RS00195	COG1982	Orn Lys Arg decarboxylase major
BTK_RS00205	COG0470	DNA polymerase III
BTK_RS00210	COG1774	PSP1 C-terminal conserved region
BTK_RS00220	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BTK_RS00230	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BTK_RS00235	COG2002	toxin-antitoxin pair type II binding
BTK_RS00245	COG0084	hydrolase, TatD family'
BTK_RS00265	COG4466	Protein conserved in bacteria
BTK_RS00280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BTK_RS00285	COG0251	oxidation-reduction process
BTK_RS00295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BTK_RS00315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTK_RS00320	COG2002	toxin-antitoxin pair type II binding
BTK_RS00325	COG2244	polysaccharide biosynthetic process
BTK_RS00330	COG3956	TIGRFAM MazG family protein
BTK_RS00335	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BTK_RS00355	COG1098	S1 RNA binding domain
BTK_RS00370	COG2208	phosphoserine phosphatase activity
BTK_RS00380	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTK_RS00385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTK_RS00400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTK_RS00405	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BTK_RS00410	COG0512	Glutamine amidotransferase of anthranilate synthase
BTK_RS00415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTK_RS00420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BTK_RS00425	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BTK_RS00430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BTK_RS00435	COG1396	sequence-specific DNA binding
BTK_RS00440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTK_RS00530	COG3880	PFAM UvrB UvrC protein
BTK_RS00540	COG0542	response to heat
BTK_RS00545	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BTK_RS00555	COG4956	integral membrane protein (PIN domain superfamily)
BTK_RS00575	COG1045	serine acetyltransferase
BTK_RS00590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTK_RS00595	COG3688	RNA-binding protein containing a PIN domain
BTK_RS00610	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTK_RS00615	COG0250	Participates in transcription elongation, termination and antitermination
BTK_RS00620	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BTK_RS00640	COG2813	Specifically methylates the guanine in position
BTK_RS00655	COG1358	cellular component organization or biogenesis
BTK_RS00660	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BTK_RS00725	COG0255	Belongs to the universal ribosomal protein uL29 family
BTK_RS00785	COG0201	protein transport
BTK_RS00795	COG0024	Methionine aminopeptidase
BTK_RS00805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BTK_RS00840	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BTK_RS00865	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTK_RS00870	COG0489	protein tyrosine kinase activity
BTK_RS00880	COG2194	sulfuric ester hydrolase activity
BTK_RS00885	COG0726	polysaccharide deacetylase
BTK_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BTK_RS00955	COG4856	YbbR-like protein
BTK_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS00995	COG2011	ABC-type metal ion transport system permease component
BTK_RS01000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BTK_RS01005	COG1464	Belongs to the NlpA lipoprotein family
BTK_RS01010	COG0604	alcohol dehydrogenase
BTK_RS01020	COG0277	FAD linked oxidase domain protein
BTK_RS01025	COG2271	Major facilitator Superfamily
BTK_RS01035	COG2814	Major facilitator Superfamily
BTK_RS01050	COG2207	Transcriptional regulator
BTK_RS01065	COG4166	transmembrane transport
BTK_RS01070	COG4166	transmembrane transport
BTK_RS01080	COG0656	L-ascorbic acid biosynthetic process
BTK_RS01095	COG4149	molybdate abc transporter
BTK_RS01100	COG0725	ABC transporter, periplasmic molybdate-binding protein
BTK_RS01105	COG1910	domain protein
BTK_RS01125	COG0697	spore germination
BTK_RS01140	COG0204	Acyl-transferase
BTK_RS01150	COG0204	Acyl-transferase
BTK_RS01160	COG1609	Transcriptional regulator
BTK_RS01170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTK_RS01190	COG5298	Protein conserved in bacteria
BTK_RS01215	COG0488	(ABC) transporter
BTK_RS01225	COG0747	negative chemotaxis
BTK_RS01235	COG0747	negative chemotaxis
BTK_RS01255	COG3344	reverse transcriptase
BTK_RS01265	COG0601	transmembrane transport
BTK_RS01270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTK_RS01275	COG0444	Belongs to the ABC transporter superfamily
BTK_RS01280	COG4608	Belongs to the ABC transporter superfamily
BTK_RS01285	COG2801	Transposase and inactivated derivatives
BTK_RS01295	COG0561	phosphatase activity
BTK_RS01330	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BTK_RS01335	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTK_RS01345	COG0531	amino acid
BTK_RS01350	COG2814	Major facilitator Superfamily
BTK_RS01360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BTK_RS01370	COG4294	response to UV
BTK_RS01375	COG0705	Rhomboid family
BTK_RS01385	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BTK_RS01390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTK_RS01395	COG0864	Transcriptional regulator
BTK_RS01400	COG2337	Toxic component of a toxin-antitoxin (TA) module
BTK_RS01405	COG2183	response to ionizing radiation
BTK_RS01500	COG0802	atpase or kinase
BTK_RS01505	COG1214	PFAM Peptidase M22, glycoprotease
BTK_RS01510	COG0456	acetyltransferase
BTK_RS01520	COG0488	(ABC) transporter
BTK_RS01535	COG1266	CAAX protease self-immunity
BTK_RS01550	COG0582	viral genome integration into host DNA
BTK_RS01570	COG3378	Phage plasmid primase P4 family
BTK_RS01630	COG0582	viral genome integration into host DNA
BTK_RS01760	COG0582	viral genome integration into host DNA
BTK_RS01845	COG4824	toxin secretion phage lysis holin
BTK_RS01880	COG2252	PERMEase
BTK_RS01890	COG5002	protein histidine kinase activity
BTK_RS01915	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BTK_RS01955	COG2205	protein histidine kinase activity
BTK_RS01960	COG0745	RESPONSE REGULATOR receiver
BTK_RS02010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTK_RS02020	COG1216	Glycosyl transferase, family 2
BTK_RS02020	COG0463	Glycosyl transferase, family 2
BTK_RS02040	COG0697	spore germination
BTK_RS02070	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTK_RS02075	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BTK_RS02080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTK_RS02090	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTK_RS02105	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BTK_RS02125	COG0151	Belongs to the GarS family
BTK_RS02155	COG0210	DNA helicase
BTK_RS02165	COG4851	CamS sex pheromone cAM373 precursor
BTK_RS02180	COG1335	isochorismatase
BTK_RS02190	COG2011	ABC-type metal ion transport system permease component
BTK_RS02195	COG1464	Belongs to the NlpA lipoprotein family
BTK_RS02210	COG0003	Pfam Anion-transporting ATPase
BTK_RS02215	COG1846	Transcriptional regulator
BTK_RS02220	COG4682	membrane
BTK_RS02240	COG1597	lipid kinase activity
BTK_RS02250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTK_RS02260	COG1012	belongs to the aldehyde dehydrogenase family
BTK_RS02265	COG2076	Multidrug Resistance protein
BTK_RS02275	COG2309	aminopeptidase activity
BTK_RS02290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTK_RS02300	COG0582	viral genome integration into host DNA
BTK_RS02345	COG1484	DNA-dependent DNA replication
BTK_RS02355	COG2002	toxin-antitoxin pair type II binding
BTK_RS02450	COG0582	viral genome integration into host DNA
BTK_RS02490	COG1802	Transcriptional regulator
BTK_RS02490	COG4626	Terminase
BTK_RS02500	COG3547	Transposase (IS116 IS110 IS902 family)
BTK_RS02505	COG0740	serine-type endopeptidase activity
BTK_RS02555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTK_RS02560	COG4807	Protein conserved in bacteria
BTK_RS02590	COG1473	amidohydrolase
BTK_RS02605	COG0450	alkyl hydroperoxide reductase
BTK_RS02625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTK_RS02630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTK_RS02635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTK_RS02645	COG0492	ferredoxin-NADP+ reductase activity
BTK_RS02660	COG0166	Belongs to the GPI family
BTK_RS02685	COG5002	protein histidine kinase activity
BTK_RS02705	COG3541	Predicted nucleotidyltransferase
BTK_RS02710	COG2814	Major facilitator Superfamily
BTK_RS02715	COG0723	plastoquinol--plastocyanin reductase activity
BTK_RS02715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTK_RS02725	COG0723	plastoquinol--plastocyanin reductase activity
BTK_RS02725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTK_RS02735	COG0765	amino acid transport
BTK_RS02740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTK_RS02750	COG0840	transmembrane signaling receptor activity
BTK_RS02775	COG0549	Belongs to the carbamate kinase family
BTK_RS02780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTK_RS02805	COG0366	Alpha amylase catalytic
BTK_RS02810	COG2190	(PTS) system
BTK_RS02810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTK_RS02810	COG1263	PTS System
BTK_RS02840	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BTK_RS02860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTK_RS02870	COG1116	anion transmembrane transporter activity
BTK_RS02915	COG2270	Major facilitator Superfamily
BTK_RS02945	COG2310	stress, protein
BTK_RS02950	COG2310	stress, protein
BTK_RS02955	COG2310	stress, protein
BTK_RS02960	COG0861	Integral membrane protein TerC family
BTK_RS02970	COG3853	Toxic anion resistance protein (TelA)
BTK_RS02985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BTK_RS02995	COG1295	ribonuclease BN
BTK_RS03000	COG2217	Heavy metal translocating P-type atpase
BTK_RS03025	COG0586	Pfam SNARE associated Golgi protein
BTK_RS03040	COG3871	stress protein (general stress protein 26)
BTK_RS03045	COG0387	Pfam Sodium calcium exchanger
BTK_RS03055	COG0535	radical SAM domain protein
BTK_RS03075	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BTK_RS03080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BTK_RS03095	COG3829	transcription factor binding
BTK_RS03105	COG0833	amino acid
BTK_RS03110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTK_RS03145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTK_RS03145	COG1263	PTS System
BTK_RS03150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTK_RS03165	COG0463	Glycosyl transferase, family 2
BTK_RS03175	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTK_RS03175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTK_RS03195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BTK_RS03215	COG1228	amidohydrolase
BTK_RS03220	COG1090	epimerase
BTK_RS03250	COG1988	membrane-bound metal-dependent
BTK_RS03255	COG1194	a g-specific adenine glycosylase
BTK_RS03280	COG1132	(ABC) transporter
BTK_RS03285	COG4129	membrane
BTK_RS03290	COG0067	glutamate synthase
BTK_RS03290	COG0069	glutamate synthase activity
BTK_RS03290	COG0070	glutamate synthase
BTK_RS03300	COG4555	ABC transporter
BTK_RS03320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTK_RS03325	COG0735	belongs to the Fur family
BTK_RS03405	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BTK_RS03430	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BTK_RS03435	COG5001	Diguanylate cyclase
BTK_RS03435	COG1716	ATPase activity
BTK_RS03445	COG2766	serine protein kinase
BTK_RS03465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTK_RS03475	COG1585	Membrane protein implicated in regulation of membrane protease activity
BTK_RS03480	COG2268	Band 7 protein
BTK_RS03490	COG3290	protein histidine kinase activity
BTK_RS03495	COG4565	transcriptional regulatory protein
BTK_RS03500	COG2851	Citrate transporter
BTK_RS03525	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BTK_RS03530	COG3842	ATPase activity
BTK_RS03535	COG1175	transmembrane transport
BTK_RS03540	COG0395	ABC-type sugar transport system, permease component
BTK_RS03550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BTK_RS03555	COG0745	RESPONSE REGULATOR receiver
BTK_RS03560	COG3850	Histidine kinase
BTK_RS03560	COG5002	protein histidine kinase activity
BTK_RS03570	COG4990	cell redox homeostasis
BTK_RS03580	COG3290	protein histidine kinase activity
BTK_RS03585	COG4565	transcriptional regulatory protein
BTK_RS03590	COG3493	citrate carrier protein
BTK_RS03595	COG0281	malic enzyme
BTK_RS03605	COG0697	spore germination
BTK_RS03610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTK_RS03620	COG5002	protein histidine kinase activity
BTK_RS03625	COG0745	RESPONSE REGULATOR receiver
BTK_RS03640	COG0456	acetyltransferase
BTK_RS03640	COG0454	-acetyltransferase
BTK_RS03645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTK_RS03650	COG3383	formate dehydrogenase (NAD+) activity
BTK_RS03655	COG2427	Protein of unknown function (DUF1641)
BTK_RS03670	COG0531	amino acid
BTK_RS03680	COG0640	Transcriptional regulator
BTK_RS03685	COG2217	Heavy metal translocating P-type atpase
BTK_RS03690	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BTK_RS03705	COG3227	Zinc metalloprotease (Elastase)
BTK_RS03725	COG2720	vancomycin resistance protein
BTK_RS03730	COG1316	TRANSCRIPTIONal
BTK_RS03735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTK_RS03750	COG3344	reverse transcriptase
BTK_RS03760	COG0346	lactoylglutathione lyase activity
BTK_RS03765	COG1253	flavin adenine dinucleotide binding
BTK_RS03770	COG1027	Aspartate ammonia-lyase
BTK_RS03775	COG1620	l-lactate permease
BTK_RS03785	COG1027	Aspartate ammonia-lyase
BTK_RS03790	COG0346	lactoylglutathione lyase activity
BTK_RS03795	COG1253	flavin adenine dinucleotide binding
BTK_RS03800	COG1027	Aspartate ammonia-lyase
BTK_RS03805	COG1620	l-lactate permease
BTK_RS03830	COG3104	oligopeptide transport
BTK_RS03835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTK_RS03840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTK_RS03845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTK_RS03855	COG2226	methyltransferase
BTK_RS03865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTK_RS03875	COG4548	von Willebrand factor, type A
BTK_RS03880	COG0714	Associated with various cellular activities
BTK_RS03900	COG0531	amino acid
BTK_RS03905	COG2188	Transcriptional regulator
BTK_RS03910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTK_RS03910	COG1263	PTS System
BTK_RS03915	COG0366	Alpha amylase catalytic
BTK_RS03930	COG0697	spore germination
BTK_RS03935	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTK_RS03940	COG1115	amino acid carrier protein
BTK_RS03950	COG1126	abc transporter atp-binding protein
BTK_RS03955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTK_RS03960	COG0765	amino acid transport
BTK_RS03965	COG0765	amino acid transport
BTK_RS03970	COG0833	amino acid
BTK_RS03985	COG1595	DNA-templated transcription, initiation
BTK_RS03995	COG2378	regulation of single-species biofilm formation
BTK_RS04000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BTK_RS04005	COG5002	protein histidine kinase activity
BTK_RS04035	COG2271	Major facilitator Superfamily
BTK_RS04040	COG1846	Transcriptional regulator
BTK_RS04045	COG0477	Major facilitator Superfamily
BTK_RS04050	COG1609	Transcriptional regulator
BTK_RS04055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTK_RS04070	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTK_RS04075	COG1879	ABC-type sugar transport system periplasmic component
BTK_RS04105	COG1063	alcohol dehydrogenase
BTK_RS04120	COG2801	Transposase and inactivated derivatives
BTK_RS04145	COG1396	sequence-specific DNA binding
BTK_RS04185	COG0730	response to heat
BTK_RS04275	COG1674	ftsk spoiiie
BTK_RS04320	COG0840	transmembrane signaling receptor activity
BTK_RS04325	COG3583	domain protein
BTK_RS04325	COG3584	3D domain protein
BTK_RS04330	COG1476	TRANSCRIPTIONal
BTK_RS04350	COG3104	oligopeptide transport
BTK_RS04355	COG1114	Component of the transport system for branched-chain amino acids
BTK_RS04370	COG1113	amino acid transport
BTK_RS04375	COG2252	PERMEase
BTK_RS04390	COG2153	protein acetylation
BTK_RS04400	COG0569	domain protein
BTK_RS04400	COG0475	glutathione-regulated potassium exporter activity
BTK_RS04410	COG1845	cytochrome c oxidase, subunit III
BTK_RS04415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTK_RS04425	COG0833	amino acid
BTK_RS04430	COG4990	cell redox homeostasis
BTK_RS04445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTK_RS04450	COG0697	spore germination
BTK_RS04455	COG0531	amino acid
BTK_RS04470	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTK_RS04475	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTK_RS04480	COG1918	ferrous iron import across plasma membrane
BTK_RS04480	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTK_RS04485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BTK_RS04490	COG0573	inorganic phosphate transmembrane transporter activity
BTK_RS04495	COG0581	inorganic phosphate transmembrane transporter activity
BTK_RS04500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTK_RS04620	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BTK_RS04640	COG0517	IMP dehydrogenase activity
BTK_RS04650	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BTK_RS04670	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BTK_RS04675	COG1116	anion transmembrane transporter activity
BTK_RS04680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTK_RS04685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTK_RS04690	COG0352	thiamine-phosphate diphosphorylase activity
BTK_RS04695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTK_RS04700	COG2104	thiamine diphosphate biosynthetic process
BTK_RS04710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTK_RS04715	COG0351	phosphomethylpyrimidine kinase
BTK_RS04755	COG2205	protein histidine kinase activity
BTK_RS04760	COG2814	Major facilitator Superfamily
BTK_RS04765	COG1846	Transcriptional regulator
BTK_RS04790	COG1136	(ABC) transporter
BTK_RS04800	COG2252	PERMEase
BTK_RS04805	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS04870	COG0778	Nitroreductase
BTK_RS04875	COG2719	SpoVR family
BTK_RS04885	COG3591	Belongs to the peptidase S1B family
BTK_RS04895	COG0446	pyridine nucleotide-disulphide oxidoreductase
BTK_RS04900	COG1937	Protein conserved in bacteria
BTK_RS04905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTK_RS04905	COG0425	Belongs to the sulfur carrier protein TusA family
BTK_RS04910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTK_RS04910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTK_RS04915	COG0425	Belongs to the sulfur carrier protein TusA family
BTK_RS04930	COG2210	Belongs to the sulfur carrier protein TusA family
BTK_RS04935	COG0730	response to heat
BTK_RS04945	COG1316	TRANSCRIPTIONal
BTK_RS04950	COG0604	alcohol dehydrogenase
BTK_RS04955	COG1283	sodium-dependent phosphate transmembrane transporter activity
BTK_RS04970	COG3711	transcriptional antiterminator
BTK_RS04970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTK_RS04975	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTK_RS04980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTK_RS05005	COG1388	LysM domain
BTK_RS05005	COG3584	3D domain protein
BTK_RS05010	COG0577	efflux transmembrane transporter activity
BTK_RS05015	COG1136	(ABC) transporter
BTK_RS05025	COG5522	Integral membrane protein (intg_mem_TP0381)
BTK_RS05040	COG1114	Component of the transport system for branched-chain amino acids
BTK_RS05045	COG3546	catalase activity
BTK_RS05080	COG0586	Pfam SNARE associated Golgi protein
BTK_RS05115	COG0531	amino acid
BTK_RS05120	COG0475	glutathione-regulated potassium exporter activity
BTK_RS05130	COG1737	Transcriptional regulator
BTK_RS05140	COG1263	PTS System
BTK_RS05140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTK_RS05150	COG2259	Doxx family
BTK_RS05170	COG1522	sequence-specific DNA binding
BTK_RS05175	COG0165	Argininosuccinate lyase
BTK_RS05175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BTK_RS05180	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS05200	COG1309	transcriptional regulator
BTK_RS05205	COG2814	Major facilitator Superfamily
BTK_RS05210	COG1733	regulation of RNA biosynthetic process
BTK_RS05225	COG4533	DNA binding
BTK_RS05230	COG2211	Major facilitator Superfamily
BTK_RS05240	COG0693	protein deglycase activity
BTK_RS05245	COG0753	catalase activity
BTK_RS05255	COG0531	amino acid
BTK_RS05270	COG1012	belongs to the aldehyde dehydrogenase family
BTK_RS05280	COG1132	(ABC) transporter
BTK_RS05285	COG1132	(ABC) transporter
BTK_RS05290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTK_RS05295	COG0765	amino acid transport
BTK_RS05300	COG1126	abc transporter atp-binding protein
BTK_RS05315	COG0189	ligase activity
BTK_RS05345	COG0028	Belongs to the TPP enzyme family
BTK_RS05350	COG3527	Alpha-acetolactate decarboxylase
BTK_RS05365	COG0561	phosphatase activity
BTK_RS05375	COG3409	Peptidoglycan-binding domain 1 protein
BTK_RS05375	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTK_RS05380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTK_RS05385	COG0318	PFAM AMP-dependent synthetase and ligase
BTK_RS05400	COG0659	secondary active sulfate transmembrane transporter activity
BTK_RS05405	COG2244	polysaccharide biosynthetic process
BTK_RS05425	COG1024	Enoyl-CoA hydratase
BTK_RS05445	COG1363	Peptidase, m42
BTK_RS05485	COG0601	transmembrane transport
BTK_RS05495	COG0444	Belongs to the ABC transporter superfamily
BTK_RS05500	COG4608	Belongs to the ABC transporter superfamily
BTK_RS05515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTK_RS05535	COG2801	Transposase and inactivated derivatives
BTK_RS05615	COG0477	Major facilitator Superfamily
BTK_RS05620	COG3290	protein histidine kinase activity
BTK_RS05625	COG4565	transcriptional regulatory protein
BTK_RS05630	COG3181	Tripartite tricarboxylate transporter family receptor
BTK_RS05635	COG0494	nUDIX hydrolase
BTK_RS05650	COG0305	Participates in initiation and elongation during chromosome replication
BTK_RS05665	COG0305	Participates in initiation and elongation during chromosome replication
BTK_RS05690	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BTK_RS05695	COG1288	antiporter activity
BTK_RS05705	COG1842	Phage shock protein A
BTK_RS05715	COG0477	Major facilitator Superfamily
BTK_RS05730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS05745	COG2801	Transposase and inactivated derivatives
BTK_RS05785	COG2020	methyltransferase activity
BTK_RS05810	COG3344	reverse transcriptase
BTK_RS05825	COG1073	alpha beta
BTK_RS05875	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BTK_RS05880	COG1522	sequence-specific DNA binding
BTK_RS05895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTK_RS05950	COG1183	phosphatidylcholine synthase activity
BTK_RS05965	COG2801	Transposase and inactivated derivatives
BTK_RS05970	COG2814	Major facilitator Superfamily
BTK_RS05975	COG0640	Transcriptional regulator
BTK_RS06000	COG2376	Dihydroxyacetone kinase
BTK_RS06060	COG2373	Large extracellular alpha-helical protein
BTK_RS06130	COG1191	sigma factor activity
BTK_RS06140	COG2208	phosphoserine phosphatase activity
BTK_RS06145	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTK_RS06150	COG0784	Response regulator, receiver
BTK_RS06150	COG2205	protein histidine kinase activity
BTK_RS06150	COG5002	protein histidine kinase activity
BTK_RS06190	COG2186	Transcriptional regulator
BTK_RS06200	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BTK_RS06220	COG0420	3'-5' exonuclease activity
BTK_RS06225	COG4717	serine-type aminopeptidase activity
BTK_RS06250	COG0346	lactoylglutathione lyase activity
BTK_RS06255	COG0346	lactoylglutathione lyase activity
BTK_RS06260	COG0457	Tetratricopeptide repeat
BTK_RS06285	COG2140	Oxalate decarboxylase
BTK_RS06290	COG3620	sequence-specific DNA binding
BTK_RS06295	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BTK_RS06300	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BTK_RS06310	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BTK_RS06325	COG1595	DNA-templated transcription, initiation
BTK_RS06335	COG0772	Belongs to the SEDS family
BTK_RS06340	COG3973	AAA domain
BTK_RS06370	COG4980	gas vesicle protein
BTK_RS06375	COG0537	adenosine 5'-monophosphoramidase activity
BTK_RS06380	COG1131	(ABC) transporter
BTK_RS06385	COG4473	ABC transporter
BTK_RS06395	COG1309	transcriptional regulator
BTK_RS06405	COG3402	PFAM membrane-flanked domain
BTK_RS06410	COG3428	Bacterial PH domain
BTK_RS06445	COG0697	spore germination
BTK_RS06450	COG3402	PFAM membrane-flanked domain
BTK_RS06455	COG3428	Bacterial PH domain
BTK_RS06460	COG2329	Antibiotic biosynthesis monooxygenase
BTK_RS06465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTK_RS06480	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BTK_RS06515	COG1309	transcriptional regulator
BTK_RS06550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS06555	COG1609	Transcriptional regulator
BTK_RS06565	COG1234	tRNA 3'-trailer cleavage
BTK_RS06570	COG0095	Lipoate-protein ligase
BTK_RS06585	COG0318	PFAM AMP-dependent synthetase and ligase
BTK_RS06595	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BTK_RS06605	COG4208	sulfate ABC transporter
BTK_RS06695	COG1073	alpha beta
BTK_RS06700	COG1408	metallophosphoesterase
BTK_RS06705	COG1078	dGTPase activity
BTK_RS06715	COG1595	DNA-templated transcription, initiation
BTK_RS06720	COG2207	Transcriptional regulator
BTK_RS06720	COG3708	Transcriptional regulator
BTK_RS06735	COG0745	RESPONSE REGULATOR receiver
BTK_RS06755	COG0501	Belongs to the peptidase M48B family
BTK_RS06760	COG0840	transmembrane signaling receptor activity
BTK_RS06765	COG3693	PFAM glycoside hydrolase, family 10
BTK_RS06775	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BTK_RS06780	COG2224	Isocitrate lyase
BTK_RS06795	COG1278	Cold shock
BTK_RS06815	COG0398	Pfam SNARE associated Golgi protein
BTK_RS06875	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTK_RS06900	COG0367	asparagine synthase
BTK_RS06915	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BTK_RS07020	COG3331	DNA recombination
BTK_RS07030	COG3331	DNA recombination
BTK_RS07055	COG3331	DNA recombination
BTK_RS07140	COG3331	DNA recombination
BTK_RS07160	COG3547	Transposase (IS116 IS110 IS902 family)
BTK_RS07285	COG4824	toxin secretion phage lysis holin
BTK_RS07315	COG0367	asparagine synthase
BTK_RS07325	COG0753	catalase activity
BTK_RS07335	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BTK_RS07360	COG3339	Conserved Protein
BTK_RS07385	COG2996	Protein conserved in bacteria
BTK_RS07410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTK_RS07425	COG0561	phosphatase activity
BTK_RS07450	COG2267	carboxylic ester hydrolase activity
BTK_RS07465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTK_RS07470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTK_RS07475	COG5504	Zn-dependent protease
BTK_RS07490	COG0180	Tryptophanyl-tRNA synthetase
BTK_RS07505	COG4166	transmembrane transport
BTK_RS07510	COG0601	transmembrane transport
BTK_RS07515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTK_RS07520	COG0444	Belongs to the ABC transporter superfamily
BTK_RS07525	COG4608	Belongs to the ABC transporter superfamily
BTK_RS07530	COG0534	Mate efflux family protein
BTK_RS07535	COG4166	transmembrane transport
BTK_RS07555	COG0861	Integral membrane protein TerC family
BTK_RS07565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTK_RS07575	COG1164	Oligoendopeptidase f
BTK_RS07590	COG2346	COG2346, Truncated hemoglobins
BTK_RS07595	COG4116	CYTH
BTK_RS07605	COG2357	RelA SpoT domain protein
BTK_RS07615	COG0564	pseudouridine synthase activity
BTK_RS07630	COG0772	Belongs to the SEDS family
BTK_RS07635	COG1216	Glycosyl transferase, family 2
BTK_RS07655	COG0457	Tetratricopeptide repeat
BTK_RS07655	COG0463	Glycosyl transferase, family 2
BTK_RS07675	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BTK_RS07690	COG1091	dTDP-4-dehydrorhamnose reductase activity
BTK_RS07730	COG0210	DNA helicase
BTK_RS07735	COG2153	protein acetylation
BTK_RS07745	COG2382	esterase
BTK_RS07770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTK_RS07785	COG0512	Glutamine amidotransferase of anthranilate synthase
BTK_RS07785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTK_RS07820	COG1620	l-lactate permease
BTK_RS07825	COG5634	Uncharacterized conserved protein (DUF2278)
BTK_RS07870	COG2801	Transposase and inactivated derivatives
BTK_RS07875	COG2226	methyltransferase
BTK_RS07895	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTK_RS07905	COG1476	TRANSCRIPTIONal
BTK_RS07940	COG2801	Transposase and inactivated derivatives
BTK_RS07955	COG4152	abc transporter atp-binding protein
BTK_RS07960	COG1668	transmembrane transport
BTK_RS07980	COG2226	methyltransferase
BTK_RS07990	COG1686	Belongs to the peptidase S11 family
BTK_RS07995	COG0681	Belongs to the peptidase S26 family
BTK_RS08030	COG1012	belongs to the aldehyde dehydrogenase family
BTK_RS08040	COG1176	ABC-type spermidine putrescine transport system, permease component I
BTK_RS08045	COG1177	transmembrane transport
BTK_RS08060	COG2409	Drug exporters of the RND superfamily
BTK_RS08070	COG0564	pseudouridine synthase activity
BTK_RS08080	COG2340	Cysteine-rich secretory protein family
BTK_RS08085	COG0247	lactate metabolic process
BTK_RS08090	COG0277	FAD linked oxidase domain protein
BTK_RS08095	COG3835	regulator
BTK_RS08105	COG0745	RESPONSE REGULATOR receiver
BTK_RS08110	COG5002	protein histidine kinase activity
BTK_RS08115	COG2186	Transcriptional regulator
BTK_RS08135	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BTK_RS08145	COG2116	formate transmembrane transporter activity
BTK_RS08150	COG0861	Integral membrane protein TerC family
BTK_RS08155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTK_RS08165	COG2030	dehydratase
BTK_RS08185	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS08190	COG3243	poly(R)-hydroxyalkanoic acid synthase
BTK_RS08200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTK_RS08215	COG1840	ABC-type Fe3 transport system, periplasmic component
BTK_RS08220	COG3842	ATPase activity
BTK_RS08245	COG1349	DNA-binding transcription factor activity
BTK_RS08260	COG0235	Class ii aldolase
BTK_RS08270	COG2861	carbohydrate metabolic process
BTK_RS08280	COG3852	Histidine kinase
BTK_RS08285	COG1846	Transcriptional regulator
BTK_RS08295	COG2318	DinB family
BTK_RS08305	COG5002	protein histidine kinase activity
BTK_RS08315	COG0720	synthase
BTK_RS08330	COG4873	Protein conserved in bacteria
BTK_RS08370	COG1780	Probably involved in ribonucleotide reductase function
BTK_RS08375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTK_RS08380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTK_RS08385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTK_RS08390	COG1725	Transcriptional regulator
BTK_RS08395	COG1131	(ABC) transporter
BTK_RS08405	COG1131	(ABC) transporter
BTK_RS08425	COG1522	sequence-specific DNA binding
BTK_RS08435	COG1335	isochorismatase
BTK_RS08445	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTK_RS08450	COG2070	2-Nitropropane dioxygenase
BTK_RS08455	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BTK_RS08465	COG1696	Membrane protein involved in D-alanine export
BTK_RS08490	COG0716	FMN binding
BTK_RS08540	COG1846	Transcriptional regulator
BTK_RS08550	COG1301	dicarboxylic acid transport
BTK_RS08555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTK_RS08560	COG4709	membrane
BTK_RS08565	COG3874	Sporulation protein YtfJ
BTK_RS08595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTK_RS08600	COG0028	Belongs to the TPP enzyme family
BTK_RS08605	COG0440	acetolactate synthase activity
BTK_RS08680	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTK_RS08695	COG1183	phosphatidylcholine synthase activity
BTK_RS08700	COG1368	sulfuric ester hydrolase activity
BTK_RS08710	COG0019	diaminopimelate decarboxylase activity
BTK_RS08730	COG0529	Catalyzes the synthesis of activated sulfate
BTK_RS08735	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTK_RS08755	COG1648	precorrin-2 dehydrogenase activity
BTK_RS08765	COG0733	neurotransmitter:sodium symporter activity
BTK_RS08785	COG1757	Na H antiporter
BTK_RS08800	COG4758	membrane
BTK_RS08805	COG4585	Histidine kinase
BTK_RS08810	COG2197	response regulator
BTK_RS08820	COG1114	Component of the transport system for branched-chain amino acids
BTK_RS08875	COG0730	response to heat
BTK_RS08880	COG0306	phosphate transporter
BTK_RS08885	COG1392	Phosphate transport regulator
BTK_RS08890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTK_RS08905	COG3852	Histidine kinase
BTK_RS08910	COG1801	Protein of unknown function DUF72
BTK_RS08920	COG0582	viral genome integration into host DNA
BTK_RS08925	COG5002	protein histidine kinase activity
BTK_RS08940	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BTK_RS08940	COG0392	lysyltransferase activity
BTK_RS08955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTK_RS08960	COG1686	Belongs to the peptidase S11 family
BTK_RS08965	COG2715	membrane protein required for spore maturation
BTK_RS08970	COG0700	Nucleoside recognition
BTK_RS08975	COG1187	pseudouridine synthase activity
BTK_RS08985	COG1333	cytochrome c biogenesis protein
BTK_RS08990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTK_RS08995	COG0745	RESPONSE REGULATOR receiver
BTK_RS09000	COG5002	protein histidine kinase activity
BTK_RS09005	COG2096	Adenosyltransferase
BTK_RS09020	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BTK_RS09025	COG1141	Ferredoxin
BTK_RS09035	COG0514	ATP-dependent DNA helicase (RecQ)
BTK_RS09040	COG1266	CAAX protease self-immunity
BTK_RS09050	COG1408	metallophosphoesterase
BTK_RS09055	COG0789	Transcriptional regulator
BTK_RS09065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTK_RS09085	COG0492	ferredoxin-NADP+ reductase activity
BTK_RS09090	COG0252	asparaginase activity
BTK_RS09160	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTK_RS09175	COG0142	geranyltranstransferase activity
BTK_RS09185	COG0142	geranyltranstransferase activity
BTK_RS09215	COG0457	Tetratricopeptide repeat
BTK_RS09235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTK_RS09240	COG2010	Cytochrome c
BTK_RS09240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTK_RS09245	COG4347	Protein of unknown function (DUF1405)
BTK_RS09260	COG2738	Putative neutral zinc metallopeptidase
BTK_RS09270	COG2801	Transposase and inactivated derivatives
BTK_RS09280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTK_RS09285	COG1694	Mazg nucleotide pyrophosphohydrolase
BTK_RS09305	COG0438	transferase activity, transferring glycosyl groups
BTK_RS09345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BTK_RS09345	COG1199	ATP-dependent helicase activity
BTK_RS09365	COG3935	DnaD domain protein
BTK_RS09370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTK_RS09380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTK_RS09380	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTK_RS09430	COG0116	Belongs to the methyltransferase superfamily
BTK_RS09440	COG1199	ATP-dependent helicase activity
BTK_RS09445	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BTK_RS09455	COG0024	Methionine aminopeptidase
BTK_RS09465	COG2233	PERMEase
BTK_RS09470	COG2311	Membrane
BTK_RS09475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTK_RS09485	COG0456	acetyltransferase
BTK_RS09525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTK_RS09540	COG3944	biosynthesis protein
BTK_RS09550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTK_RS09565	COG1215	transferase activity, transferring glycosyl groups
BTK_RS09570	COG0438	transferase activity, transferring glycosyl groups
BTK_RS09585	COG0454	-acetyltransferase
BTK_RS09605	COG0328	RNA-DNA hybrid ribonuclease activity
BTK_RS09640	COG3403	YqcI/YcgG family
BTK_RS09645	COG1280	lysine exporter protein (LysE YggA)
BTK_RS09665	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTK_RS09670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTK_RS09680	COG0475	glutathione-regulated potassium exporter activity
BTK_RS09685	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTK_RS09690	COG4978	Transcriptional regulator
BTK_RS09690	COG0789	Transcriptional regulator
BTK_RS09700	COG2323	membrane
BTK_RS09705	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BTK_RS09745	COG1923	regulation of RNA biosynthetic process
BTK_RS09755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BTK_RS09760	COG1360	Flagellar Motor Protein
BTK_RS09765	COG2201	protein-glutamate methylesterase activity
BTK_RS09770	COG0643	Histidine kinase
BTK_RS09770	COG2198	Histidine kinase
BTK_RS09775	COG1776	CheC inhibitor of MCP methylation
BTK_RS09775	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTK_RS09790	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTK_RS09810	COG1256	bacterial-type flagellum assembly
BTK_RS09815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTK_RS09835	COG1815	bacterial-type flagellum-dependent cell motility
BTK_RS09840	COG1558	bacterial-type flagellum-dependent cell motility
BTK_RS09850	COG1766	The M ring may be actively involved in energy transduction
BTK_RS09855	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTK_RS09865	COG1157	protein secretion by the type III secretion system
BTK_RS09900	COG0835	chemotaxis
BTK_RS09900	COG0784	Response regulator, receiver
BTK_RS09910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTK_RS09915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTK_RS09920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTK_RS09925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTK_RS09930	COG0741	lytic transglycosylase activity
BTK_RS09940	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTK_RS09945	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTK_RS09945	COG1776	CheC inhibitor of MCP methylation
BTK_RS09955	COG1338	Plays a role in the flagellum-specific transport system
BTK_RS09960	COG1987	bacterial-type flagellum assembly
BTK_RS09970	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTK_RS09975	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTK_RS09980	COG1419	protein localization to endoplasmic reticulum
BTK_RS09985	COG4786	Flagellar basal body rod
BTK_RS09990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTK_RS10050	COG0583	DNA-binding transcription factor activity
BTK_RS10055	COG3842	ATPase activity
BTK_RS10060	COG0725	ABC transporter, periplasmic molybdate-binding protein
BTK_RS10095	COG0406	alpha-ribazole phosphatase activity
BTK_RS10110	COG3547	Transposase (IS116 IS110 IS902 family)
BTK_RS10130	COG0367	asparagine synthase
BTK_RS10160	COG1802	Transcriptional regulator
BTK_RS10165	COG0697	spore germination
BTK_RS10175	COG0523	cobalamin synthesis protein
BTK_RS10180	COG0701	Predicted permease
BTK_RS10195	COG1757	Na H antiporter
BTK_RS10200	COG0789	Transcriptional regulator
BTK_RS10235	COG0534	Mate efflux family protein
BTK_RS10240	COG3340	Belongs to the peptidase S51 family
BTK_RS10260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTK_RS10280	COG2733	membrane
BTK_RS10315	COG1131	(ABC) transporter
BTK_RS10335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTK_RS10340	COG0528	UMP kinase activity
BTK_RS10355	COG1027	Aspartate ammonia-lyase
BTK_RS10360	COG0281	malic enzyme
BTK_RS10365	COG4191	Histidine kinase
BTK_RS10370	COG0784	Response regulator, receiver
BTK_RS10375	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTK_RS10400	COG2801	Transposase and inactivated derivatives
BTK_RS10410	COG3620	sequence-specific DNA binding
BTK_RS10450	COG2814	Major facilitator Superfamily
BTK_RS10470	COG1695	Transcriptional regulator
BTK_RS10480	COG0477	Major facilitator Superfamily
BTK_RS10490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTK_RS10495	COG2223	nitrite transmembrane transporter activity
BTK_RS10500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTK_RS10520	COG0733	neurotransmitter:sodium symporter activity
BTK_RS10525	COG5566	PFAM Mor transcription activator
BTK_RS10530	COG2323	membrane
BTK_RS10550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTK_RS10560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTK_RS10565	COG0028	Belongs to the TPP enzyme family
BTK_RS10585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTK_RS10610	COG2814	Major facilitator Superfamily
BTK_RS10615	COG3384	dioxygenase
BTK_RS10625	COG3279	Response regulator of the LytR AlgR family
BTK_RS10630	COG0427	acetyl-CoA hydrolase
BTK_RS10650	COG4166	transmembrane transport
BTK_RS10655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS10660	COG1914	H( )-stimulated, divalent metal cation uptake system
BTK_RS10675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTK_RS10685	COG0531	amino acid
BTK_RS10720	COG1309	transcriptional regulator
BTK_RS10725	COG2390	Transcriptional regulator
BTK_RS10735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTK_RS10740	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BTK_RS10755	COG4846	Membrane protein involved in cytochrome C biogenesis
BTK_RS10765	COG0006	proline dipeptidase activity
BTK_RS10775	COG2132	Multicopper oxidase
BTK_RS10785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTK_RS10805	COG1114	Component of the transport system for branched-chain amino acids
BTK_RS10815	COG2372	response to copper ion
BTK_RS10815	COG1276	copper resistance
BTK_RS10820	COG4549	nuclear export factor GLE1
BTK_RS10825	COG0697	spore germination
BTK_RS10830	COG0583	DNA-binding transcription factor activity
BTK_RS10835	COG1959	2 iron, 2 sulfur cluster binding
BTK_RS10840	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BTK_RS10845	COG0778	Nitroreductase
BTK_RS10860	COG0628	permease
BTK_RS10870	COG1231	oxidoreductase activity
BTK_RS10875	COG0523	cobalamin synthesis protein
BTK_RS10885	COG0411	ABC transporter
BTK_RS10905	COG0583	DNA-binding transcription factor activity
BTK_RS10915	COG1942	4-Oxalocrotonate Tautomerase
BTK_RS10935	COG1271	oxidase subunit
BTK_RS10940	COG1294	oxidase, subunit
BTK_RS10945	COG4988	ABC transporter
BTK_RS10950	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BTK_RS10960	COG1216	Glycosyl transferase, family 2
BTK_RS11000	COG1686	Belongs to the peptidase S11 family
BTK_RS11015	COG1388	LysM domain
BTK_RS11015	COG0791	NLP P60 protein
BTK_RS11025	COG1132	(ABC) transporter
BTK_RS11030	COG0745	RESPONSE REGULATOR receiver
BTK_RS11035	COG5002	protein histidine kinase activity
BTK_RS11040	COG0300	oxidoreductase activity
BTK_RS11075	COG0460	homoserine dehydrogenase
BTK_RS11100	COG1316	TRANSCRIPTIONal
BTK_RS11110	COG0745	RESPONSE REGULATOR receiver
BTK_RS11115	COG5002	protein histidine kinase activity
BTK_RS11130	COG1285	pathogenesis
BTK_RS11135	COG1247	-acetyltransferase
BTK_RS11180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTK_RS11190	COG1082	Xylose isomerase domain protein TIM barrel
BTK_RS11200	COG2814	Major facilitator Superfamily
BTK_RS11205	COG1279	arginine transmembrane transporter activity
BTK_RS11210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTK_RS11220	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTK_RS11255	COG0577	efflux transmembrane transporter activity
BTK_RS11260	COG2002	toxin-antitoxin pair type II binding
BTK_RS11265	COG1404	Belongs to the peptidase S8 family
BTK_RS11270	COG0640	Transcriptional regulator
BTK_RS11275	COG0667	Aldo Keto reductase
BTK_RS11280	COG2814	Major facilitator Superfamily
BTK_RS11290	COG3152	Membrane
BTK_RS11315	COG0840	transmembrane signaling receptor activity
BTK_RS11335	COG3949	Membrane
BTK_RS11340	COG0783	Belongs to the Dps family
BTK_RS11355	COG2801	Transposase and inactivated derivatives
BTK_RS11365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTK_RS11375	COG1231	oxidoreductase activity
BTK_RS11380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS11385	COG4989	oxidoreductase activity
BTK_RS11395	COG0523	cobalamin synthesis protein
BTK_RS11400	COG0456	acetyltransferase
BTK_RS11405	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTK_RS11425	COG3344	reverse transcriptase
BTK_RS11435	COG0702	epimerase
BTK_RS11445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTK_RS11455	COG4166	transmembrane transport
BTK_RS11480	COG5337	Spore coat protein CotH
BTK_RS11485	COG1051	belongs to the nudix hydrolase family
BTK_RS11490	COG0586	Pfam SNARE associated Golgi protein
BTK_RS11495	COG2244	polysaccharide biosynthetic process
BTK_RS11505	COG0701	Predicted permease
BTK_RS11510	COG3689	TIGRFAM TIGR03943 family protein
BTK_RS11515	COG1607	acyl-coa hydrolase
BTK_RS11520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTK_RS11535	COG0702	epimerase
BTK_RS11540	COG2839	Protein conserved in bacteria
BTK_RS11545	COG1253	flavin adenine dinucleotide binding
BTK_RS11560	COG2801	Transposase and inactivated derivatives
BTK_RS11565	COG2963	transposase activity
BTK_RS11570	COG1114	Component of the transport system for branched-chain amino acids
BTK_RS11575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTK_RS11595	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTK_RS11605	COG1876	peptidase activity
BTK_RS11620	COG2211	Major facilitator Superfamily
BTK_RS11635	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTK_RS11645	COG0561	phosphatase activity
BTK_RS11735	COG0561	phosphatase activity
BTK_RS11750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTK_RS11760	COG1819	glycosyl
BTK_RS11765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTK_RS11770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTK_RS11800	COG0456	acetyltransferase
BTK_RS11835	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTK_RS11930	COG3874	Sporulation protein YtfJ
BTK_RS11955	COG2226	methyltransferase
BTK_RS11975	COG1082	Xylose isomerase domain protein TIM barrel
BTK_RS11980	COG0346	lactoylglutathione lyase activity
BTK_RS11990	COG0604	alcohol dehydrogenase
BTK_RS12000	COG1595	DNA-templated transcription, initiation
BTK_RS12015	COG0426	domain, Protein
BTK_RS12015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTK_RS12030	COG0386	Belongs to the glutathione peroxidase family
BTK_RS12035	COG1305	Transglutaminase-like
BTK_RS12040	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BTK_RS12045	COG0714	Associated with various cellular activities
BTK_RS12055	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BTK_RS12060	COG1140	nitrate reductase beta subunit
BTK_RS12065	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BTK_RS12070	COG2181	nitrate reductase activity
BTK_RS12075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTK_RS12080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTK_RS12085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTK_RS12090	COG0303	'Molybdopterin
BTK_RS12095	COG0314	molybdopterin synthase activity
BTK_RS12100	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BTK_RS12105	COG2223	nitrite transmembrane transporter activity
BTK_RS12115	COG1648	precorrin-2 dehydrogenase activity
BTK_RS12125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BTK_RS12125	COG1587	Uroporphyrinogen-III synthase
BTK_RS12130	COG2146	nitrite reductase [NAD(P)H] activity
BTK_RS12140	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BTK_RS12175	COG2359	stage V sporulation protein S
BTK_RS12200	COG0730	response to heat
BTK_RS12240	COG1418	mRNA catabolic process
BTK_RS12245	COG0488	(ABC) transporter
BTK_RS12360	COG0629	single-stranded DNA binding
BTK_RS12370	COG1413	lyase activity
BTK_RS12385	COG2521	methyltransferase
BTK_RS12385	COG2136	Putative SAM-dependent methyltransferase
BTK_RS12390	COG0018	arginyl-trna synthetase
BTK_RS12435	COG2801	Transposase and inactivated derivatives
BTK_RS12440	COG2963	transposase activity
BTK_RS12450	COG0017	Asparaginyl-tRNA synthetase
BTK_RS12455	COG0733	neurotransmitter:sodium symporter activity
BTK_RS12480	COG2610	gluconate transmembrane transporter activity
BTK_RS12490	COG1794	racemase activity, acting on amino acids and derivatives
BTK_RS12500	COG0456	acetyltransferase
BTK_RS12510	COG3655	Transcriptional regulator
BTK_RS12515	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTK_RS12525	COG1131	(ABC) transporter
BTK_RS12530	COG4473	ABC transporter
BTK_RS12540	COG0546	phosphoglycolate phosphatase activity
BTK_RS12555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTK_RS12570	COG0768	penicillin binding
BTK_RS12580	COG0204	Acyl-transferase
BTK_RS12585	COG1272	protein, Hemolysin III
BTK_RS12595	COG0805	protein transport
BTK_RS12605	COG1307	EDD domain protein, DegV family
BTK_RS12615	COG1999	signal sequence binding
BTK_RS12620	COG0071	Belongs to the small heat shock protein (HSP20) family
BTK_RS12625	COG0367	asparagine synthase
BTK_RS12645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTK_RS12650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTK_RS12670	COG1335	isochorismatase
BTK_RS12680	COG0668	transmembrane transport
BTK_RS12685	COG2203	Gaf domain
BTK_RS12685	COG4585	Histidine kinase
BTK_RS12690	COG2197	response regulator
BTK_RS12695	COG1737	Transcriptional regulator
BTK_RS12700	COG0384	phenazine biosynthesis protein PhzF
BTK_RS12705	COG1064	alcohol dehydrogenase
BTK_RS12730	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BTK_RS12765	COG1125	glycine betaine transport
BTK_RS12765	COG0517	IMP dehydrogenase activity
BTK_RS12770	COG1174	glycine betaine transport
BTK_RS12805	COG1253	flavin adenine dinucleotide binding
BTK_RS12810	COG1012	belongs to the aldehyde dehydrogenase family
BTK_RS12815	COG5506	Protein of unknown function (DUF1694)
BTK_RS12830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTK_RS12835	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BTK_RS12840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BTK_RS12845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTK_RS12850	COG0456	acetyltransferase
BTK_RS12855	COG3829	transcription factor binding
BTK_RS12860	COG1509	lysine 2,3-aminomutase activity
BTK_RS12895	COG3064	Membrane
BTK_RS12895	COG0515	serine threonine protein kinase
BTK_RS12895	COG4991	sh3 domain protein
BTK_RS12905	COG0671	phosphoesterase, PA-phosphatase related
BTK_RS12910	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTK_RS12915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTK_RS12995	COG0300	oxidoreductase activity
BTK_RS13025	COG2814	Major facilitator Superfamily
BTK_RS13030	COG4841	protein insertion into membrane
BTK_RS13035	COG0372	Belongs to the citrate synthase family
BTK_RS13040	COG2079	MmgE PrpD family protein
BTK_RS13045	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BTK_RS13050	COG1960	acyl-CoA dehydrogenase activity
BTK_RS13055	COG2084	Dehydrogenase
BTK_RS13065	COG1280	lysine exporter protein (LysE YggA)
BTK_RS13070	COG1024	Enoyl-CoA hydratase
BTK_RS13085	COG0420	3'-5' exonuclease activity
BTK_RS13090	COG0419	ATPase involved in DNA repair
BTK_RS13115	COG2223	nitrite transmembrane transporter activity
BTK_RS13120	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS13125	COG1169	isochorismate synthase
BTK_RS13130	COG1021	2,3-dihydroxybenzoate-AMP ligase
BTK_RS13135	COG3433	isochorismatase activity
BTK_RS13135	COG1535	isochorismatase
BTK_RS13145	COG3251	PFAM MbtH domain protein
BTK_RS13150	COG2814	Major facilitator Superfamily
BTK_RS13165	COG0776	regulation of translation
BTK_RS13175	COG2318	DinB family
BTK_RS13185	COG1115	amino acid carrier protein
BTK_RS13200	COG2329	Antibiotic biosynthesis monooxygenase
BTK_RS13205	COG1187	pseudouridine synthase activity
BTK_RS13210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTK_RS13215	COG1136	(ABC) transporter
BTK_RS13225	COG0028	Belongs to the TPP enzyme family
BTK_RS13265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTK_RS13290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTK_RS13325	COG1247	-acetyltransferase
BTK_RS13350	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BTK_RS13360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS13390	COG0583	DNA-binding transcription factor activity
BTK_RS13395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTK_RS13415	COG0583	DNA-binding transcription factor activity
BTK_RS13420	COG2258	MOSC domain
BTK_RS13435	COG1132	(ABC) transporter
BTK_RS13440	COG1132	(ABC) transporter
BTK_RS13465	COG1396	sequence-specific DNA binding
BTK_RS13500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTK_RS13505	COG1595	DNA-templated transcription, initiation
BTK_RS13530	COG1649	PFAM Uncharacterised BCR, COG1649
BTK_RS13550	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BTK_RS13555	COG2971	BadF BadG BcrA BcrD
BTK_RS13575	COG1846	Transcriptional regulator
BTK_RS13595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTK_RS13615	COG1309	transcriptional regulator
BTK_RS13635	COG3615	Tellurite resistance protein tehB
BTK_RS13635	COG0500	methyltransferase
BTK_RS13645	COG2226	methyltransferase
BTK_RS13650	COG3961	Belongs to the TPP enzyme family
BTK_RS13655	COG1846	Transcriptional regulator
BTK_RS13685	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTK_RS13710	COG2002	toxin-antitoxin pair type II binding
BTK_RS13715	COG2963	transposase activity
BTK_RS13720	COG2801	Transposase and inactivated derivatives
BTK_RS13730	COG0730	response to heat
BTK_RS13735	COG0110	maltose O-acetyltransferase activity
BTK_RS13740	COG1686	Belongs to the peptidase S11 family
BTK_RS13750	COG2814	Major facilitator Superfamily
BTK_RS13780	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS13810	COG0741	lytic transglycosylase activity
BTK_RS13820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS13825	COG2239	Acts as a magnesium transporter
BTK_RS13900	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTK_RS13900	COG3409	Peptidoglycan-binding domain 1 protein
BTK_RS13915	COG3831	ATPase activity
BTK_RS13945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTK_RS13975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTK_RS13985	COG3850	Histidine kinase
BTK_RS13985	COG5002	protein histidine kinase activity
BTK_RS13990	COG0577	efflux transmembrane transporter activity
BTK_RS14010	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BTK_RS14020	COG1690	Belongs to the RtcB family
BTK_RS14030	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BTK_RS14050	COG2814	Major facilitator Superfamily
BTK_RS14125	COG0346	lactoylglutathione lyase activity
BTK_RS14140	COG1522	sequence-specific DNA binding
BTK_RS14145	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS14150	COG1309	transcriptional regulator
BTK_RS14155	COG2814	Major facilitator Superfamily
BTK_RS14165	COG0640	Transcriptional regulator
BTK_RS14170	COG0346	lactoylglutathione lyase activity
BTK_RS14175	COG0798	PFAM Bile acid sodium symporter
BTK_RS14185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS14195	COG1575	Belongs to the MenA family. Type 1 subfamily
BTK_RS14200	COG0456	acetyltransferase
BTK_RS14210	COG5609	conserved protein (DUF2294)
BTK_RS14225	COG0288	reversible hydration of carbon dioxide
BTK_RS14230	COG0657	acetylesterase activity
BTK_RS14255	COG0415	Belongs to the DNA photolyase family
BTK_RS14300	COG0598	Magnesium transport protein CorA
BTK_RS14335	COG0583	DNA-binding transcription factor activity
BTK_RS14355	COG1335	isochorismatase
BTK_RS14360	COG2267	carboxylic ester hydrolase activity
BTK_RS14365	COG0737	Belongs to the 5'-nucleotidase family
BTK_RS14385	COG2207	Transcriptional regulator
BTK_RS14410	COG5002	protein histidine kinase activity
BTK_RS14415	COG1063	alcohol dehydrogenase
BTK_RS14435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTK_RS14440	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS14445	COG1522	sequence-specific DNA binding
BTK_RS14460	COG3848	Pyruvate phosphate dikinase
BTK_RS14460	COG0574	Belongs to the PEP-utilizing enzyme family
BTK_RS14475	COG2963	transposase activity
BTK_RS14480	COG2801	Transposase and inactivated derivatives
BTK_RS14490	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BTK_RS14500	COG0454	-acetyltransferase
BTK_RS14510	COG3314	Sporulation integral membrane protein YlbJ
BTK_RS14525	COG1960	acyl-CoA dehydrogenase activity
BTK_RS14535	COG0640	Transcriptional regulator
BTK_RS14540	COG3142	Participates in the control of copper homeostasis
BTK_RS14550	COG1414	Transcriptional regulator
BTK_RS14555	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BTK_RS14560	COG1984	allophanate hydrolase subunit 2
BTK_RS14640	COG0833	amino acid
BTK_RS14650	COG0730	response to heat
BTK_RS14690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTK_RS14695	COG0697	spore germination
BTK_RS14710	COG0456	acetyltransferase
BTK_RS14715	COG0590	tRNA wobble adenosine to inosine editing
BTK_RS14715	COG0037	tRNA processing
BTK_RS14740	COG4884	unkown
BTK_RS14740	COG3831	ATPase activity
BTK_RS14760	COG1846	Transcriptional regulator
BTK_RS14765	COG0778	Nitroreductase
BTK_RS14850	COG0714	Associated with various cellular activities
BTK_RS14890	COG0753	catalase activity
BTK_RS14895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTK_RS14920	COG0463	Glycosyl transferase, family 2
BTK_RS14965	COG0714	Associated with various cellular activities
BTK_RS14995	COG0346	lactoylglutathione lyase activity
BTK_RS15000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS15020	COG3655	Transcriptional regulator
BTK_RS15030	COG1785	Belongs to the alkaline phosphatase family
BTK_RS15035	COG2720	vancomycin resistance protein
BTK_RS15045	COG3239	Fatty acid desaturase
BTK_RS15055	COG0833	amino acid
BTK_RS15060	COG1414	Transcriptional regulator
BTK_RS15065	COG4187	Peptidase family M20/M25/M40
BTK_RS15070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTK_RS15085	COG2801	Transposase and inactivated derivatives
BTK_RS15095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTK_RS15115	COG2329	Antibiotic biosynthesis monooxygenase
BTK_RS15140	COG1070	Carbohydrate kinase
BTK_RS15145	COG2390	Transcriptional regulator
BTK_RS15155	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTK_RS15165	COG1879	ABC-type sugar transport system periplasmic component
BTK_RS15185	COG0277	FAD linked oxidase domain protein
BTK_RS15235	COG1605	Chorismate mutase
BTK_RS15235	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTK_RS15250	COG0287	Prephenate dehydrogenase
BTK_RS15265	COG1309	transcriptional regulator
BTK_RS15270	COG1033	growth of symbiont in host cell
BTK_RS15270	COG2409	Drug exporters of the RND superfamily
BTK_RS15280	COG2409	Drug exporters of the RND superfamily
BTK_RS15280	COG1033	growth of symbiont in host cell
BTK_RS15285	COG0488	(ABC) transporter
BTK_RS15290	COG1368	sulfuric ester hydrolase activity
BTK_RS15295	COG0861	Integral membrane protein TerC family
BTK_RS15305	COG0346	lactoylglutathione lyase activity
BTK_RS15310	COG4912	Dna alkylation repair
BTK_RS15330	COG0697	spore germination
BTK_RS15350	COG2746	aminoglycoside 3-N-acetyltransferase activity
BTK_RS15380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTK_RS15385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTK_RS15390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTK_RS15405	COG0628	permease
BTK_RS15465	COG1131	(ABC) transporter
BTK_RS15480	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BTK_RS15490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTK_RS15495	COG0436	Aminotransferase
BTK_RS15530	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BTK_RS15545	COG2261	transglycosylase associated protein
BTK_RS15565	COG2814	Major facilitator Superfamily
BTK_RS15565	COG0477	Major facilitator Superfamily
BTK_RS15570	COG4533	DNA binding
BTK_RS15575	COG0789	Transcriptional regulator
BTK_RS15580	COG1664	Polymer-forming cytoskeletal
BTK_RS15630	COG1307	EDD domain protein, DegV family
BTK_RS15635	COG1164	Oligoendopeptidase f
BTK_RS15645	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTK_RS15665	COG0745	RESPONSE REGULATOR receiver
BTK_RS15670	COG3850	Histidine kinase
BTK_RS15670	COG5002	protein histidine kinase activity
BTK_RS15715	COG0667	Aldo Keto reductase
BTK_RS15730	COG4948	Mandelate Racemase Muconate Lactonizing
BTK_RS15740	COG4166	transmembrane transport
BTK_RS15750	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BTK_RS15760	COG0586	Pfam SNARE associated Golgi protein
BTK_RS15800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTK_RS15805	COG3938	Belongs to the proline racemase family
BTK_RS15815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTK_RS15820	COG1012	belongs to the aldehyde dehydrogenase family
BTK_RS15825	COG1115	amino acid carrier protein
BTK_RS15830	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTK_RS15835	COG1162	GTPase activity
BTK_RS15850	COG3397	chitin binding
BTK_RS15865	COG4637	Psort location Cytoplasmic, score
BTK_RS15880	COG2801	Transposase and inactivated derivatives
BTK_RS15900	COG2801	Transposase and inactivated derivatives
BTK_RS15920	COG0514	ATP-dependent DNA helicase (RecQ)
BTK_RS15925	COG2105	PFAM AIG2 family protein
BTK_RS15935	COG3973	AAA domain
BTK_RS15940	COG0456	acetyltransferase
BTK_RS15985	COG2315	Protein conserved in bacteria
BTK_RS15990	COG2226	methyltransferase
BTK_RS15995	COG2205	protein histidine kinase activity
BTK_RS16015	COG1819	glycosyl
BTK_RS16020	COG3397	chitin binding
BTK_RS16025	COG2153	protein acetylation
BTK_RS16055	COG4175	Glycine betaine
BTK_RS16055	COG0517	IMP dehydrogenase activity
BTK_RS16060	COG4176	ABC-type proline glycine betaine transport system permease component
BTK_RS16100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTK_RS16100	COG0456	acetyltransferase
BTK_RS16105	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS16120	COG2814	Major facilitator Superfamily
BTK_RS16130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTK_RS16135	COG0022	dehydrogenase e1 component
BTK_RS16140	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTK_RS16145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTK_RS16155	COG1959	2 iron, 2 sulfur cluster binding
BTK_RS16190	COG3284	Transcriptional regulator
BTK_RS16220	COG1309	transcriptional regulator
BTK_RS16260	COG2959	enzyme of heme biosynthesis
BTK_RS16275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS16315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTK_RS16320	COG0697	spore germination
BTK_RS16325	COG0201	protein transport
BTK_RS16340	COG0737	Belongs to the 5'-nucleotidase family
BTK_RS16345	COG3227	Zinc metalloprotease (Elastase)
BTK_RS16350	COG1523	belongs to the glycosyl hydrolase 13 family
BTK_RS16365	COG0076	glutamate decarboxylase activity
BTK_RS16370	COG0657	acetylesterase activity
BTK_RS16375	COG1073	alpha beta
BTK_RS16380	COG0577	efflux transmembrane transporter activity
BTK_RS16385	COG1136	(ABC) transporter
BTK_RS16400	COG5002	protein histidine kinase activity
BTK_RS16405	COG0745	RESPONSE REGULATOR receiver
BTK_RS16410	COG1011	Hydrolase
BTK_RS16435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTK_RS16455	COG0322	excinuclease ABC activity
BTK_RS16495	COG4667	esterase of the alpha-beta hydrolase superfamily
BTK_RS16520	COG3878	Protein conserved in bacteria
BTK_RS16545	COG0592	DNA-directed DNA polymerase activity
BTK_RS16560	COG2223	nitrite transmembrane transporter activity
BTK_RS16570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTK_RS16605	COG0697	spore germination
BTK_RS16610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTK_RS16625	COG0584	glycerophosphoryl diester phosphodiesterase
BTK_RS16650	COG2814	Major facilitator Superfamily
BTK_RS16695	COG0768	penicillin binding
BTK_RS16700	COG0671	phosphoesterase, PA-phosphatase related
BTK_RS16705	COG0604	alcohol dehydrogenase
BTK_RS16710	COG5002	protein histidine kinase activity
BTK_RS16715	COG0745	RESPONSE REGULATOR receiver
BTK_RS16725	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTK_RS16740	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTK_RS16780	COG0582	viral genome integration into host DNA
BTK_RS16785	COG2205	protein histidine kinase activity
BTK_RS16805	COG1794	racemase activity, acting on amino acids and derivatives
BTK_RS16810	COG1819	glycosyl
BTK_RS16820	COG0768	penicillin binding
BTK_RS16825	COG5002	protein histidine kinase activity
BTK_RS16830	COG0561	phosphatase activity
BTK_RS16865	COG2124	cytochrome p450
BTK_RS16890	COG3547	Transposase (IS116 IS110 IS902 family)
BTK_RS16925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BTK_RS16935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTK_RS16940	COG0460	homoserine dehydrogenase
BTK_RS16960	COG0577	efflux transmembrane transporter activity
BTK_RS16965	COG1136	(ABC) transporter
BTK_RS16975	COG0488	(ABC) transporter
BTK_RS16980	COG2205	protein histidine kinase activity
BTK_RS16985	COG3344	reverse transcriptase
BTK_RS16995	COG0745	RESPONSE REGULATOR receiver
BTK_RS17005	COG3773	Cell wall hydrolase
BTK_RS17010	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BTK_RS17020	COG3386	PFAM SMP-30 Gluconolaconase
BTK_RS17030	COG0693	protein deglycase activity
BTK_RS17035	COG2323	membrane
BTK_RS17055	COG3344	reverse transcriptase
BTK_RS17080	COG2368	4-hydroxyphenylacetate
BTK_RS17085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTK_RS17115	COG1131	(ABC) transporter
BTK_RS17125	COG0583	DNA-binding transcription factor activity
BTK_RS17130	COG1942	4-Oxalocrotonate Tautomerase
BTK_RS17185	COG2207	Transcriptional regulator
BTK_RS17190	COG3227	Zinc metalloprotease (Elastase)
BTK_RS17205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTK_RS17230	COG1686	Belongs to the peptidase S11 family
BTK_RS17245	COG0572	uridine kinase
BTK_RS17285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTK_RS17290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BTK_RS17295	COG1024	Enoyl-CoA hydratase
BTK_RS17300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTK_RS17305	COG0511	ligase activity, forming carbon-carbon bonds
BTK_RS17310	COG0439	Biotin carboxylase
BTK_RS17315	COG1960	acyl-CoA dehydrogenase activity
BTK_RS17330	COG1309	transcriptional regulator
BTK_RS17340	COG1131	(ABC) transporter
BTK_RS17355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTK_RS17370	COG0768	penicillin binding
BTK_RS17375	COG0768	penicillin binding
BTK_RS17385	COG1595	DNA-templated transcription, initiation
BTK_RS17390	COG0768	penicillin binding
BTK_RS17400	COG2239	Acts as a magnesium transporter
BTK_RS17405	COG0772	Belongs to the SEDS family
BTK_RS17430	COG0076	glutamate decarboxylase activity
BTK_RS17440	COG1533	DNA photolyase activity
BTK_RS17465	COG0814	amino acid
BTK_RS17470	COG1760	l-serine dehydratase
BTK_RS17475	COG1760	l-serine dehydratase
BTK_RS17505	COG0367	asparagine synthase
BTK_RS17510	COG1309	transcriptional regulator
BTK_RS17530	COG1396	sequence-specific DNA binding
BTK_RS17630	COG5444	nuclease activity
BTK_RS17655	COG1876	peptidase activity
BTK_RS17660	COG2843	Capsule synthesis protein
BTK_RS17670	COG0477	Major facilitator Superfamily
BTK_RS17685	COG1846	Transcriptional regulator
BTK_RS17690	COG2814	Major facilitator Superfamily
BTK_RS17705	COG2031	fatty acid transporter
BTK_RS17715	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTK_RS17770	COG1288	antiporter activity
BTK_RS17785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BTK_RS17795	COG1733	regulation of RNA biosynthetic process
BTK_RS17800	COG0778	Nitroreductase
BTK_RS17810	COG0469	pyruvate kinase activity
BTK_RS17830	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS17840	COG1131	(ABC) transporter
BTK_RS17865	COG1011	Hydrolase
BTK_RS17875	COG2365	Tyrosine phosphatase family
BTK_RS17910	COG0628	permease
BTK_RS17935	COG0500	methyltransferase
BTK_RS17945	COG0477	Major facilitator Superfamily
BTK_RS17975	COG1253	flavin adenine dinucleotide binding
BTK_RS17980	COG0789	Transcriptional regulator
BTK_RS17990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTK_RS18020	COG0697	spore germination
BTK_RS18030	COG1357	PFAM Pentapeptide repeats (8 copies)
BTK_RS18035	COG3813	Protein conserved in bacteria
BTK_RS18040	COG2706	6-phosphogluconolactonase activity
BTK_RS18045	COG1070	Carbohydrate kinase
BTK_RS18055	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BTK_RS18060	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BTK_RS18065	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BTK_RS18070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTK_RS18100	COG0840	transmembrane signaling receptor activity
BTK_RS18110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTK_RS18110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTK_RS18115	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTK_RS18115	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTK_RS18120	COG1733	regulation of RNA biosynthetic process
BTK_RS18135	COG0814	amino acid
BTK_RS18160	COG2188	Transcriptional regulator
BTK_RS18165	COG0673	inositol 2-dehydrogenase activity
BTK_RS18185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTK_RS18205	COG0384	phenazine biosynthesis protein PhzF
BTK_RS18225	COG0318	PFAM AMP-dependent synthetase and ligase
BTK_RS18230	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTK_RS18235	COG1733	regulation of RNA biosynthetic process
BTK_RS18260	COG1191	sigma factor activity
BTK_RS18315	COG1151	hydroxylamine reductase activity
BTK_RS18370	COG1113	amino acid transport
BTK_RS18375	COG2814	Major facilitator Superfamily
BTK_RS18405	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BTK_RS18410	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTK_RS18420	COG1247	-acetyltransferase
BTK_RS18425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTK_RS18430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTK_RS18435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTK_RS18440	COG3739	integral membrane protein
BTK_RS18460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS18475	COG0583	DNA-binding transcription factor activity
BTK_RS18485	COG2890	protein-(glutamine-N5) methyltransferase activity
BTK_RS18500	COG1193	negative regulation of DNA recombination
BTK_RS18510	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BTK_RS18515	COG1164	Oligoendopeptidase f
BTK_RS18545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTK_RS18570	COG0584	glycerophosphoryl diester phosphodiesterase
BTK_RS18585	COG0640	Transcriptional regulator
BTK_RS18590	COG0604	alcohol dehydrogenase
BTK_RS18605	COG0457	Tetratricopeptide repeat
BTK_RS18615	COG0385	Bile acid
BTK_RS18620	COG0277	FAD linked oxidase domain protein
BTK_RS18645	COG1183	phosphatidylcholine synthase activity
BTK_RS18655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTK_RS18655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTK_RS18660	COG1252	NADH dehydrogenase
BTK_RS18670	COG0823	Involved in the tonB-independent uptake of proteins
BTK_RS18675	COG3397	chitin binding
BTK_RS18685	COG0697	spore germination
BTK_RS18705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTK_RS18715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTK_RS18725	COG0457	Tetratricopeptide repeat
BTK_RS18755	COG1404	Belongs to the peptidase S8 family
BTK_RS18800	COG0488	(ABC) transporter
BTK_RS18825	COG3852	Histidine kinase
BTK_RS18835	COG1285	pathogenesis
BTK_RS18845	COG2514	catechol 2,3-dioxygenase activity
BTK_RS18850	COG2720	vancomycin resistance protein
BTK_RS18890	COG0716	FMN binding
BTK_RS18925	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS18935	COG0165	Argininosuccinate lyase
BTK_RS18950	COG4145	pantothenate transmembrane transporter activity
BTK_RS18960	COG1012	belongs to the aldehyde dehydrogenase family
BTK_RS18965	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS18975	COG1657	PFAM Prenyltransferase squalene oxidase
BTK_RS18980	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BTK_RS18985	COG2962	Rard protein
BTK_RS18990	COG3326	Membrane
BTK_RS19005	COG0489	protein tyrosine kinase activity
BTK_RS19015	COG0314	molybdopterin synthase activity
BTK_RS19020	COG0303	'Molybdopterin
BTK_RS19025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTK_RS19030	COG2116	formate transmembrane transporter activity
BTK_RS19040	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTK_RS19045	COG5609	conserved protein (DUF2294)
BTK_RS19050	COG2427	Protein of unknown function (DUF1641)
BTK_RS19055	COG3383	formate dehydrogenase (NAD+) activity
BTK_RS19065	COG0697	spore germination
BTK_RS19080	COG0531	amino acid
BTK_RS19115	COG2226	methyltransferase
BTK_RS19120	COG4166	transmembrane transport
BTK_RS19125	COG4166	transmembrane transport
BTK_RS19130	COG4166	transmembrane transport
BTK_RS19135	COG1316	TRANSCRIPTIONal
BTK_RS19145	COG1595	DNA-templated transcription, initiation
BTK_RS19155	COG1131	(ABC) transporter
BTK_RS19175	COG0673	inositol 2-dehydrogenase activity
BTK_RS19180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTK_RS19185	COG0187	DNA topoisomerase II activity
BTK_RS19195	COG1832	CoA-binding protein
BTK_RS19200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTK_RS19205	COG0745	RESPONSE REGULATOR receiver
BTK_RS19215	COG1328	CTP reductase activity
BTK_RS19215	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BTK_RS19225	COG4841	protein insertion into membrane
BTK_RS19230	COG0824	Thioesterase
BTK_RS19265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTK_RS19280	COG1132	(ABC) transporter
BTK_RS19285	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTK_RS19315	COG2211	Major facilitator Superfamily
BTK_RS19325	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTK_RS19340	COG0183	Belongs to the thiolase family
BTK_RS19345	COG0318	PFAM AMP-dependent synthetase and ligase
BTK_RS19350	COG1268	BioY protein
BTK_RS19355	COG0318	PFAM AMP-dependent synthetase and ligase
BTK_RS19360	COG1396	sequence-specific DNA binding
BTK_RS19385	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BTK_RS19405	COG0830	nickel cation binding
BTK_RS19445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTK_RS19455	COG5002	protein histidine kinase activity
BTK_RS19460	COG0400	carboxylic ester hydrolase activity
BTK_RS19465	COG0346	lactoylglutathione lyase activity
BTK_RS19480	COG0069	glutamate synthase activity
BTK_RS19485	COG1902	pentaerythritol trinitrate reductase activity
BTK_RS19490	COG3344	reverse transcriptase
BTK_RS19500	COG1329	Transcriptional regulator
BTK_RS19505	COG0010	Belongs to the arginase family
BTK_RS19530	COG2226	methyltransferase
BTK_RS19560	COG4846	Membrane protein involved in cytochrome C biogenesis
BTK_RS19565	COG0785	Cytochrome C biogenesis protein
BTK_RS19575	COG1473	amidohydrolase
BTK_RS19580	COG2963	transposase activity
BTK_RS19585	COG2801	Transposase and inactivated derivatives
BTK_RS19610	COG0583	DNA-binding transcription factor activity
BTK_RS19620	COG1346	cytolysis
BTK_RS19635	COG0730	response to heat
BTK_RS19660	COG1132	(ABC) transporter
BTK_RS19665	COG1132	(ABC) transporter
BTK_RS19700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTK_RS19705	COG0737	Belongs to the 5'-nucleotidase family
BTK_RS19715	COG0737	Belongs to the 5'-nucleotidase family
BTK_RS19725	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTK_RS19745	COG1695	Transcriptional regulator
BTK_RS19750	COG0174	glutamine synthetase
BTK_RS19755	COG0789	Transcriptional regulator
BTK_RS19760	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BTK_RS19765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTK_RS19770	COG2860	membrane
BTK_RS19775	COG0464	growth
BTK_RS19810	COG3584	3D domain protein
BTK_RS19810	COG1388	LysM domain
BTK_RS19815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTK_RS19815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTK_RS19815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTK_RS19820	COG1105	Belongs to the carbohydrate kinase PfkB family
BTK_RS19825	COG1349	DNA-binding transcription factor activity
BTK_RS19830	COG1979	alcohol dehydrogenase
BTK_RS19835	COG2322	membrane
BTK_RS19850	COG1113	amino acid transport
BTK_RS19860	COG1408	metallophosphoesterase
BTK_RS19865	COG2116	formate transmembrane transporter activity
BTK_RS19880	COG2217	Heavy metal translocating P-type atpase
BTK_RS19885	COG2608	mercury ion transmembrane transporter activity
BTK_RS19890	COG1937	Protein conserved in bacteria
BTK_RS19900	COG2819	hydrolase of the alpha beta superfamily
BTK_RS19905	COG1120	ATPase activity
BTK_RS19910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTK_RS19915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTK_RS19920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTK_RS19925	COG2169	Transcriptional regulator
BTK_RS19930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTK_RS19935	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BTK_RS19955	COG2267	carboxylic ester hydrolase activity
BTK_RS19960	COG3300	MHYT domain
BTK_RS19960	COG5001	Diguanylate cyclase
BTK_RS19980	COG1086	Polysaccharide biosynthesis protein
BTK_RS20000	COG1346	cytolysis
BTK_RS20010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTK_RS20020	COG2188	Transcriptional regulator
BTK_RS20025	COG2723	6-phospho-beta-galactosidase activity
BTK_RS20030	COG0823	Involved in the tonB-independent uptake of proteins
BTK_RS20035	COG1404	Belongs to the peptidase S8 family
BTK_RS20040	COG3773	Cell wall hydrolase
BTK_RS20050	COG1368	sulfuric ester hydrolase activity
BTK_RS20055	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTK_RS20080	COG4550	Control of competence regulator ComK, YlbF/YmcA
BTK_RS20090	COG1013	pyruvate-flavodoxin oxidoreductase activity
BTK_RS20095	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BTK_RS20095	COG0674	pyruvate-flavodoxin oxidoreductase activity
BTK_RS20105	COG2359	stage V sporulation protein S
BTK_RS20110	COG1692	metallophosphoesterase
BTK_RS20130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTK_RS20135	COG1426	Protein conserved in bacteria
BTK_RS20150	COG0300	oxidoreductase activity
BTK_RS20155	COG0612	Peptidase, M16
BTK_RS20160	COG0612	Peptidase, M16
BTK_RS20165	COG1079	Belongs to the binding-protein-dependent transport system permease family
BTK_RS20170	COG4603	Belongs to the binding-protein-dependent transport system permease family
BTK_RS20175	COG3845	ABC transporter
BTK_RS20180	COG1744	ABC transporter substrate-binding protein PnrA-like
BTK_RS20185	COG2188	Transcriptional regulator
BTK_RS20200	COG0740	serine-type endopeptidase activity
BTK_RS20205	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTK_RS20220	COG0527	aspartate kinase activity
BTK_RS20225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTK_RS20230	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTK_RS20235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTK_RS20240	COG1873	PFAM PRC-barrel domain
BTK_RS20245	COG0612	Peptidase, M16
BTK_RS20250	COG0726	polysaccharide deacetylase
BTK_RS20265	COG0196	riboflavin kinase activity
BTK_RS20275	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BTK_RS20280	COG1550	Protein conserved in bacteria
BTK_RS20290	COG1358	cellular component organization or biogenesis
BTK_RS20295	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BTK_RS20300	COG0195	Participates in both transcription termination and antitermination
BTK_RS20320	COG0750	zinc metalloprotease
BTK_RS20330	COG4589	Belongs to the CDS family
BTK_RS20375	COG4974	Belongs to the 'phage' integrase family
BTK_RS20385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTK_RS20390	COG0758	DNA mediated transformation
BTK_RS20395	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BTK_RS20435	COG1837	Belongs to the UPF0109 family
BTK_RS20445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTK_RS20455	COG0552	protein localization to endoplasmic reticulum
BTK_RS20460	COG1196	nuclear chromosome segregation
BTK_RS20465	COG3344	reverse transcriptase
BTK_RS20470	COG1196	nuclear chromosome segregation
BTK_RS20480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTK_RS20485	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS20490	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BTK_RS20505	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BTK_RS20510	COG1461	Dihydroxyacetone kinase
BTK_RS20515	COG1302	Protein conserved in bacteria
BTK_RS20530	COG1564	THIamine pyrophosphokinase
BTK_RS20535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BTK_RS20545	COG2815	serine threonine protein kinase
BTK_RS20545	COG0515	serine threonine protein kinase
BTK_RS20550	COG0631	protein serine/threonine phosphatase activity
BTK_RS20560	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTK_RS20560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTK_RS20575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BTK_RS20580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTK_RS20600	COG1561	YicC-like family, N-terminal region
BTK_RS20605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BTK_RS20615	COG0006	proline dipeptidase activity
BTK_RS20630	COG3069	C4-dicarboxylate transmembrane transporter activity
BTK_RS20690	COG0564	pseudouridine synthase activity
BTK_RS20710	COG3599	regulation of cell shape
BTK_RS20715	COG2302	S4 RNA-binding domain
BTK_RS20720	COG0762	integral membrane protein
BTK_RS20730	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BTK_RS20740	COG1873	PFAM PRC-barrel domain
BTK_RS20745	COG1191	sigma factor activity
BTK_RS20750	COG1191	sigma factor activity
BTK_RS20760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BTK_RS20765	COG0849	cell division
BTK_RS20785	COG0772	Belongs to the SEDS family
BTK_RS20805	COG0768	penicillin binding
BTK_RS20810	COG0768	penicillin binding
BTK_RS20830	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTK_RS20845	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BTK_RS20850	COG1399	metal-binding, possibly nucleic acid-binding protein
BTK_RS20860	COG3480	Lon protease (S16) C-terminal proteolytic domain
BTK_RS20865	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTK_RS20870	COG3314	Sporulation integral membrane protein YlbJ
BTK_RS20880	COG0742	ribosomal rna small subunit methyltransferase
BTK_RS20895	COG3679	Belongs to the UPF0342 family
BTK_RS20900	COG0406	alpha-ribazole phosphatase activity
BTK_RS20915	COG2340	Cysteine-rich secretory protein family
BTK_RS20930	COG3336	cytochrome c oxidase
BTK_RS20965	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BTK_RS20970	COG0772	Belongs to the SEDS family
BTK_RS20980	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BTK_RS20985	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BTK_RS20995	COG4896	Protein conserved in bacteria
BTK_RS21010	COG1217	gtp-binding protein TYPA
BTK_RS21020	COG0483	inositol monophosphate 1-phosphatase activity
BTK_RS21040	COG1982	Orn Lys Arg decarboxylase major
BTK_RS21085	COG0022	dehydrogenase e1 component
BTK_RS21090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTK_RS21105	COG0561	phosphatase activity
BTK_RS21115	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTK_RS21120	COG0569	domain protein
BTK_RS21140	COG0583	DNA-binding transcription factor activity
BTK_RS21145	COG0517	IMP dehydrogenase activity
BTK_RS21155	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BTK_RS21165	COG4703	Protein of unknown function (DUF1797)
BTK_RS21180	COG2200	EAL domain
BTK_RS21185	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS21190	COG1408	metallophosphoesterase
BTK_RS21235	COG2814	Major facilitator Superfamily
BTK_RS21260	COG3209	COG3209 Rhs family protein
BTK_RS21270	COG2205	protein histidine kinase activity
BTK_RS21280	COG0436	Aminotransferase
BTK_RS21285	COG1609	Transcriptional regulator
BTK_RS21290	COG3833	ABC-type maltose transport systems, permease component
BTK_RS21295	COG1175	transmembrane transport
BTK_RS21300	COG2182	Extracellular solute-binding protein
BTK_RS21310	COG0366	Alpha amylase catalytic
BTK_RS21315	COG3842	ATPase activity
BTK_RS21350	COG0183	Belongs to the thiolase family
BTK_RS21385	COG1695	Transcriptional regulator
BTK_RS21390	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS21410	COG4974	Belongs to the 'phage' integrase family
BTK_RS21440	COG0640	Transcriptional regulator
BTK_RS21470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTK_RS21475	COG0436	Aminotransferase
BTK_RS21510	COG2084	Dehydrogenase
BTK_RS21520	COG2199	diguanylate cyclase activity
BTK_RS21525	COG0778	Nitroreductase
BTK_RS21550	COG1263	PTS System
BTK_RS21550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTK_RS21550	COG2190	(PTS) system
BTK_RS21555	COG3711	transcriptional antiterminator
BTK_RS21565	COG2188	Transcriptional regulator
BTK_RS21575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BTK_RS21605	COG1547	Domain of unknown function (DUF309)
BTK_RS21610	COG0456	acetyltransferase
BTK_RS21620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTK_RS21625	COG4086	secreted protein
BTK_RS21630	COG0561	phosphatase activity
BTK_RS21635	COG0697	spore germination
BTK_RS21650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTK_RS21695	COG1686	Belongs to the peptidase S11 family
BTK_RS21700	COG1725	Transcriptional regulator
BTK_RS21705	COG1131	(ABC) transporter
BTK_RS21720	COG1846	Transcriptional regulator
BTK_RS21735	COG0598	Magnesium transport protein CorA
BTK_RS21760	COG4974	Belongs to the 'phage' integrase family
BTK_RS21770	COG0735	belongs to the Fur family
BTK_RS21775	COG1300	Membrane
BTK_RS21795	COG0667	Aldo Keto reductase
BTK_RS21800	COG0656	L-ascorbic acid biosynthetic process
BTK_RS21805	COG0456	acetyltransferase
BTK_RS21805	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTK_RS21815	COG4085	toxin activity
BTK_RS21815	COG0737	Belongs to the 5'-nucleotidase family
BTK_RS21815	COG1525	nuclease
BTK_RS21825	COG0596	Alpha beta hydrolase
BTK_RS21830	COG2056	Na+-H+ antiporter family
BTK_RS21835	COG1609	Transcriptional regulator
BTK_RS21840	COG0456	acetyltransferase
BTK_RS21845	COG1073	alpha beta
BTK_RS21860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTK_RS21860	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTK_RS21865	COG0307	riboflavin synthase, alpha
BTK_RS21895	COG1073	alpha beta
BTK_RS21895	COG2226	methyltransferase
BTK_RS21910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTK_RS21920	COG1757	Na H antiporter
BTK_RS21935	COG1522	sequence-specific DNA binding
BTK_RS21980	COG0300	oxidoreductase activity
BTK_RS21985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTK_RS21990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTK_RS21995	COG1760	l-serine dehydratase
BTK_RS22000	COG1760	l-serine dehydratase
BTK_RS22035	COG1285	pathogenesis
BTK_RS22050	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTK_RS22055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS22070	COG1376	ErfK ybiS ycfS ynhG family protein
BTK_RS22075	COG4129	membrane
BTK_RS22080	COG1126	abc transporter atp-binding protein
BTK_RS22085	COG0765	amino acid transport
BTK_RS22090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTK_RS22115	COG2323	membrane
BTK_RS22120	COG0772	Belongs to the SEDS family
BTK_RS22130	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTK_RS22135	COG0022	dehydrogenase e1 component
BTK_RS22140	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTK_RS22145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTK_RS22160	COG0280	phosphate acetyltransferase
BTK_RS22170	COG3290	protein histidine kinase activity
BTK_RS22170	COG3829	transcription factor binding
BTK_RS22180	COG0584	glycerophosphoryl diester phosphodiesterase
BTK_RS22185	COG3093	addiction module antidote protein HigA
BTK_RS22205	COG0750	zinc metalloprotease
BTK_RS22220	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BTK_RS22230	COG0142	geranyltranstransferase activity
BTK_RS22255	COG1302	Protein conserved in bacteria
BTK_RS22260	COG0439	Biotin carboxylase
BTK_RS22265	COG0511	ligase activity, forming carbon-carbon bonds
BTK_RS22310	COG3854	ATPases associated with a variety of cellular activities
BTK_RS22335	COG0006	proline dipeptidase activity
BTK_RS22350	COG3872	metal-dependent enzyme
BTK_RS22360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTK_RS22395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTK_RS22405	COG1609	Transcriptional regulator
BTK_RS22415	COG2076	Multidrug Resistance protein
BTK_RS22420	COG2076	Multidrug Resistance protein
BTK_RS22455	COG1131	(ABC) transporter
BTK_RS22460	COG1725	Transcriptional regulator
BTK_RS22490	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTK_RS22555	COG1459	type II secretion system
BTK_RS22560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BTK_RS22615	COG0646	methionine synthase
BTK_RS22615	COG1410	methionine synthase
BTK_RS22620	COG0646	methionine synthase
BTK_RS22620	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BTK_RS22630	COG0626	cystathionine gamma-synthase activity
BTK_RS22635	COG0626	cystathionine gamma-synthase activity
BTK_RS22655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTK_RS22665	COG1940	carbohydrate kinase activity
BTK_RS22670	COG4483	Protein conserved in bacteria
BTK_RS22675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTK_RS22680	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BTK_RS22685	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTK_RS22690	COG0704	Plays a role in the regulation of phosphate uptake
BTK_RS22700	COG0573	inorganic phosphate transmembrane transporter activity
BTK_RS22705	COG0573	inorganic phosphate transmembrane transporter activity
BTK_RS22710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BTK_RS22715	COG0768	penicillin binding
BTK_RS22720	COG0477	Major facilitator Superfamily
BTK_RS22725	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTK_RS22735	COG5521	maltodextrose utilization protein MalA
BTK_RS22750	COG0735	belongs to the Fur family
BTK_RS22755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTK_RS22760	COG1121	(ABC) transporter
BTK_RS22765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTK_RS22795	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BTK_RS22800	COG2384	SAM-dependent methyltransferase
BTK_RS22810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTK_RS22815	COG0358	DNA primase activity
BTK_RS22830	COG0517	IMP dehydrogenase activity
BTK_RS22845	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BTK_RS22850	COG0295	cytidine deaminase activity
BTK_RS22855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BTK_RS22865	COG1480	7TM receptor with intracellular HD hydrolase
BTK_RS22870	COG1702	phosphate starvation-inducible protein PhoH
BTK_RS22895	COG1610	YqeY-like protein
BTK_RS22900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BTK_RS22905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTK_RS22910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BTK_RS22940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTK_RS22945	COG1733	regulation of RNA biosynthetic process
BTK_RS22970	COG1466	dna polymerase III delta subunit
BTK_RS22980	COG2333	competence protein COMEC
BTK_RS22980	COG0658	competence protein
BTK_RS22985	COG2131	deaminase
BTK_RS22990	COG1555	photosystem II stabilization
BTK_RS22990	COG1596	polysaccharide export
BTK_RS22995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTK_RS23000	COG2226	methyltransferase
BTK_RS23005	COG0799	negative regulation of ribosome biogenesis
BTK_RS23010	COG1713	HD superfamily hydrolase involved in NAD metabolism
BTK_RS23020	COG1534	Rna-binding protein
BTK_RS23030	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BTK_RS23035	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BTK_RS23060	COG1595	DNA-templated transcription, initiation
BTK_RS23070	COG0778	Nitroreductase
BTK_RS23075	COG2357	RelA SpoT domain protein
BTK_RS23085	COG1785	Belongs to the alkaline phosphatase family
BTK_RS23095	COG2267	carboxylic ester hydrolase activity
BTK_RS23145	COG3186	Phenylalanine-4-hydroxylase
BTK_RS23155	COG2514	catechol 2,3-dioxygenase activity
BTK_RS23160	COG2259	Doxx family
BTK_RS23200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTK_RS23210	COG1454	alcohol dehydrogenase
BTK_RS23210	COG1012	belongs to the aldehyde dehydrogenase family
BTK_RS23215	COG0626	cystathionine gamma-synthase activity
BTK_RS23220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTK_RS23245	COG0768	penicillin binding
BTK_RS23265	COG0826	peptidase U32
BTK_RS23270	COG0826	peptidase U32
BTK_RS23275	COG4122	O-methyltransferase activity
BTK_RS23280	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BTK_RS23310	COG0628	permease
BTK_RS23330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BTK_RS23345	COG1104	cysteine desulfurase activity
BTK_RS23350	COG1959	2 iron, 2 sulfur cluster binding
BTK_RS23370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BTK_RS23395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTK_RS23405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BTK_RS23405	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BTK_RS23410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTK_RS23415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTK_RS23415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTK_RS23430	COG2323	membrane
BTK_RS23440	COG1862	Preprotein translocase
BTK_RS23470	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BTK_RS23500	COG0157	Belongs to the NadC ModD family
BTK_RS23505	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BTK_RS23510	COG1104	cysteine desulfurase activity
BTK_RS23515	COG1827	regulation of RNA biosynthetic process
BTK_RS23520	COG2258	MOSC domain
BTK_RS23525	COG0077	Prephenate dehydratase
BTK_RS23530	COG0577	efflux transmembrane transporter activity
BTK_RS23535	COG0577	efflux transmembrane transporter activity
BTK_RS23540	COG1136	(ABC) transporter
BTK_RS23545	COG5002	protein histidine kinase activity
BTK_RS23550	COG0745	RESPONSE REGULATOR receiver
BTK_RS23560	COG3290	protein histidine kinase activity
BTK_RS23570	COG2868	ribosomal protein
BTK_RS23580	COG1530	ribonuclease E activity
BTK_RS23585	COG1994	Peptidase M50
BTK_RS23590	COG0739	heme binding
BTK_RS23595	COG2894	cell division
BTK_RS23615	COG1077	Cell shape determining protein MreB Mrl
BTK_RS23635	COG0285	dihydrofolate synthase activity
BTK_RS23650	COG1388	LysM domain
BTK_RS23660	COG0113	porphobilinogen synthase activity
BTK_RS23665	COG1587	Uroporphyrinogen-III synthase
BTK_RS23675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTK_RS23685	COG1846	Transcriptional regulator
BTK_RS23690	COG1764	response to oxidative stress
BTK_RS23705	COG1067	ATP-dependent peptidase activity
BTK_RS23705	COG0470	DNA polymerase III
BTK_RS23755	COG0622	Phosphoesterase
BTK_RS23770	COG5401	PFAM Sporulation and spore germination
BTK_RS23790	COG2197	response regulator
BTK_RS23795	COG2233	PERMEase
BTK_RS23800	COG0402	S-adenosylhomocysteine deaminase activity
BTK_RS23805	COG1983	PspC domain protein
BTK_RS23810	COG1396	sequence-specific DNA binding
BTK_RS23815	COG0697	spore germination
BTK_RS23825	COG1959	2 iron, 2 sulfur cluster binding
BTK_RS23830	COG1668	transmembrane transport
BTK_RS23835	COG4152	abc transporter atp-binding protein
BTK_RS23840	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BTK_RS23845	COG1360	Flagellar Motor Protein
BTK_RS23850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BTK_RS23855	COG1876	peptidase activity
BTK_RS23860	COG0824	Thioesterase
BTK_RS23865	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BTK_RS23870	COG1053	succinate dehydrogenase
BTK_RS23875	COG2009	succinate dehydrogenase
BTK_RS23880	COG1719	4-vinyl reductase, 4VR
BTK_RS23890	COG3118	belongs to the thioredoxin family
BTK_RS23895	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BTK_RS23900	COG2086	electron transfer activity
BTK_RS23905	COG1024	Enoyl-CoA hydratase
BTK_RS23910	COG1309	transcriptional regulator
BTK_RS23915	COG0318	PFAM AMP-dependent synthetase and ligase
BTK_RS23940	COG2318	DinB family
BTK_RS23970	COG1131	(ABC) transporter
BTK_RS23975	COG2205	protein histidine kinase activity
BTK_RS23980	COG0745	RESPONSE REGULATOR receiver
BTK_RS23990	COG4895	conserved protein (DUF2196)
BTK_RS23995	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BTK_RS24005	COG4509	Sortase family
BTK_RS24010	COG1120	ATPase activity
BTK_RS24025	COG5386	Cell surface protein
BTK_RS24035	COG5386	Cell surface protein
BTK_RS24040	COG1114	Component of the transport system for branched-chain amino acids
BTK_RS24045	COG1187	pseudouridine synthase activity
BTK_RS24060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTK_RS24060	COG1796	DNA polymerase
BTK_RS24065	COG1286	toxin biosynthetic process
BTK_RS24110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTK_RS24120	COG1418	mRNA catabolic process
BTK_RS24140	COG2814	Major facilitator Superfamily
BTK_RS24145	COG1566	PFAM secretion protein HlyD family protein
BTK_RS24150	COG1309	transcriptional regulator
BTK_RS24155	COG1363	Peptidase, m42
BTK_RS24180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTK_RS24195	COG1484	DNA-dependent DNA replication
BTK_RS24200	COG3611	Membrane attachment protein
BTK_RS24210	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BTK_RS24215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTK_RS24225	COG1971	Probably functions as a manganese efflux pump
BTK_RS24235	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTK_RS24235	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTK_RS24240	COG5002	protein histidine kinase activity
BTK_RS24245	COG0745	RESPONSE REGULATOR receiver
BTK_RS24265	COG0538	isocitrate dehydrogenase activity
BTK_RS24270	COG0372	Belongs to the citrate synthase family
BTK_RS24285	COG0628	permease
BTK_RS24290	COG3030	protein affecting phage T7 exclusion by the F plasmid
BTK_RS24315	COG1725	Transcriptional regulator
BTK_RS24320	COG0281	malic enzyme
BTK_RS24325	COG0587	DNA-directed DNA polymerase activity
BTK_RS24340	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BTK_RS24355	COG4109	DRTGG domain
BTK_RS24370	COG0006	proline dipeptidase activity
BTK_RS24405	COG0662	Cupin 2, conserved barrel domain protein
BTK_RS24420	COG0686	Belongs to the AlaDH PNT family
BTK_RS24425	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS24430	COG0589	response to stress
BTK_RS24475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTK_RS24500	COG0827	DNA restriction-modification system
BTK_RS24505	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BTK_RS24510	COG3874	Sporulation protein YtfJ
BTK_RS24525	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BTK_RS24535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTK_RS24550	COG1104	cysteine desulfurase activity
BTK_RS24560	COG0583	DNA-binding transcription factor activity
BTK_RS24565	COG0697	spore germination
BTK_RS24570	COG1309	transcriptional regulator
BTK_RS24575	COG1956	GAF domain-containing protein
BTK_RS24580	COG0626	cystathionine gamma-synthase activity
BTK_RS24620	COG1595	DNA-templated transcription, initiation
BTK_RS24630	COG0110	maltose O-acetyltransferase activity
BTK_RS24635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTK_RS24640	COG0454	-acetyltransferase
BTK_RS24645	COG0517	IMP dehydrogenase activity
BTK_RS24650	COG0123	including yeast histone deacetylase and acetoin utilization protein
BTK_RS24665	COG0745	RESPONSE REGULATOR receiver
BTK_RS24675	COG0666	response to abiotic stimulus
BTK_RS24680	COG2972	Histidine kinase
BTK_RS24680	COG0745	RESPONSE REGULATOR receiver
BTK_RS24700	COG3279	Response regulator of the LytR AlgR family
BTK_RS24735	COG1609	Transcriptional regulator
BTK_RS24745	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTK_RS24745	COG1605	Chorismate mutase
BTK_RS24750	COG4851	CamS sex pheromone cAM373 precursor
BTK_RS24755	COG3118	belongs to the thioredoxin family
BTK_RS24765	COG2309	aminopeptidase activity
BTK_RS24780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS24795	COG1674	ftsk spoiiie
BTK_RS24810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTK_RS24820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTK_RS24825	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BTK_RS24830	COG1363	Peptidase, m42
BTK_RS24840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTK_RS24860	COG1523	belongs to the glycosyl hydrolase 13 family
BTK_RS24875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTK_RS24880	COG1349	DNA-binding transcription factor activity
BTK_RS24885	COG1187	pseudouridine synthase activity
BTK_RS24890	COG2244	polysaccharide biosynthetic process
BTK_RS24895	COG2081	HI0933 family
BTK_RS24900	COG2814	Major facilitator Superfamily
BTK_RS24910	COG3832	glyoxalase III activity
BTK_RS24930	COG1329	Transcriptional regulator
BTK_RS24955	COG0314	molybdopterin synthase activity
BTK_RS24960	COG1763	Mo-molybdopterin cofactor biosynthetic process
BTK_RS24965	COG0303	'Molybdopterin
BTK_RS24975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTK_RS24980	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTK_RS25005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTK_RS25015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTK_RS25070	COG2814	Major facilitator Superfamily
BTK_RS25075	COG0475	glutathione-regulated potassium exporter activity
BTK_RS25080	COG0490	domain, Protein
BTK_RS25085	COG0582	viral genome integration into host DNA
BTK_RS25095	COG1136	(ABC) transporter
BTK_RS25115	COG1242	4 iron, 4 sulfur cluster binding
BTK_RS25120	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BTK_RS25125	COG1794	racemase activity, acting on amino acids and derivatives
BTK_RS25145	COG2267	carboxylic ester hydrolase activity
BTK_RS25150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTK_RS25155	COG0671	phosphoesterase, PA-phosphatase related
BTK_RS25160	COG0438	transferase activity, transferring glycosyl groups
BTK_RS25185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS25230	COG0546	phosphoglycolate phosphatase activity
BTK_RS25235	COG1349	DNA-binding transcription factor activity
BTK_RS25245	COG5002	protein histidine kinase activity
BTK_RS25250	COG3852	Histidine kinase
BTK_RS25255	COG2267	carboxylic ester hydrolase activity
BTK_RS25260	COG1368	sulfuric ester hydrolase activity
BTK_RS25280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTK_RS25285	COG1116	anion transmembrane transporter activity
BTK_RS25290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTK_RS25310	COG0494	nUDIX hydrolase
BTK_RS25340	COG1854	S-ribosylhomocysteine lyase activity
BTK_RS25350	COG0288	reversible hydration of carbon dioxide
BTK_RS25355	COG1271	oxidase subunit
BTK_RS25360	COG1294	oxidase, subunit
BTK_RS25375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTK_RS25395	COG1842	Phage shock protein A
BTK_RS25425	COG5002	protein histidine kinase activity
BTK_RS25430	COG0745	RESPONSE REGULATOR receiver
BTK_RS25455	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTK_RS25460	COG1597	lipid kinase activity
BTK_RS25490	COG0586	Pfam SNARE associated Golgi protein
BTK_RS25500	COG0577	efflux transmembrane transporter activity
BTK_RS25505	COG1136	(ABC) transporter
BTK_RS25510	COG2207	Transcriptional regulator
BTK_RS25510	COG3708	Transcriptional regulator
BTK_RS25520	COG5658	integral membrane protein
BTK_RS25525	COG0640	Transcriptional regulator
BTK_RS25530	COG0745	RESPONSE REGULATOR receiver
BTK_RS25535	COG2205	protein histidine kinase activity
BTK_RS25540	COG0577	efflux transmembrane transporter activity
BTK_RS25545	COG0577	efflux transmembrane transporter activity
BTK_RS25550	COG1136	(ABC) transporter
BTK_RS25555	COG0577	efflux transmembrane transporter activity
BTK_RS25585	COG2801	Transposase and inactivated derivatives
BTK_RS25590	COG2188	Transcriptional regulator
BTK_RS25610	COG3964	amidohydrolase
BTK_RS25630	COG4948	Mandelate Racemase Muconate Lactonizing
BTK_RS25650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BTK_RS25655	COG0596	Alpha beta hydrolase
BTK_RS25665	COG1169	isochorismate synthase
BTK_RS25670	COG1575	Belongs to the MenA family. Type 1 subfamily
BTK_RS25675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BTK_RS25710	COG0058	SHG alpha-glucan phosphorylase activity
BTK_RS25720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BTK_RS25835	COG0544	peptidyl-prolyl cis-trans isomerase activity
BTK_RS25870	COG1285	pathogenesis
BTK_RS25875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTK_RS25895	COG2155	Conserved Protein
BTK_RS25900	COG1098	S1 RNA binding domain
BTK_RS25905	COG0436	Aminotransferase
BTK_RS25910	COG1522	sequence-specific DNA binding
BTK_RS25920	COG2267	carboxylic ester hydrolase activity
BTK_RS25930	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BTK_RS25950	COG5018	Exonuclease
BTK_RS25955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTK_RS25980	COG2801	Transposase and inactivated derivatives
BTK_RS25985	COG2050	protein possibly involved in aromatic compounds catabolism
BTK_RS25995	COG1268	BioY protein
BTK_RS26000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTK_RS26005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTK_RS26020	COG3584	3D domain protein
BTK_RS26035	COG1252	NADH dehydrogenase
BTK_RS26050	COG3708	Transcriptional regulator
BTK_RS26065	COG1683	Conserved Protein
BTK_RS26135	COG4824	toxin secretion phage lysis holin
BTK_RS26200	COG0740	serine-type endopeptidase activity
BTK_RS26210	COG1802	Transcriptional regulator
BTK_RS26210	COG4626	Terminase
BTK_RS26260	COG0582	viral genome integration into host DNA
BTK_RS26350	COG1396	sequence-specific DNA binding
BTK_RS26385	COG2963	transposase activity
BTK_RS26390	COG2801	Transposase and inactivated derivatives
BTK_RS26395	COG0316	Belongs to the HesB IscA family
BTK_RS26410	COG1252	NADH dehydrogenase
BTK_RS26425	COG0390	transport system, permease component
BTK_RS26430	COG2824	Alkylphosphonate utilization operon protein PhnA
BTK_RS26475	COG4837	Protein of unknown function (DUF1462)
BTK_RS26480	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BTK_RS26490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTK_RS26495	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BTK_RS26515	COG1358	cellular component organization or biogenesis
BTK_RS26525	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTK_RS26530	COG0647	UMP catabolic process
BTK_RS26540	COG2445	Protein of unknown function DUF86
BTK_RS26545	COG1494	fructose-1,6-bisphosphatase
BTK_RS26570	COG4470	Protein conserved in bacteria
BTK_RS26580	COG0789	Transcriptional regulator
BTK_RS26585	COG4377	Putative membrane peptidase family (DUF2324)
BTK_RS26610	COG0739	heme binding
BTK_RS26620	COG3377	Domain of unknown function (DUF1805)
BTK_RS26625	COG0737	Belongs to the 5'-nucleotidase family
BTK_RS26630	COG0719	Fe-S assembly protein
BTK_RS26635	COG0822	iron-sulfur transferase activity
BTK_RS26640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BTK_RS26650	COG0396	ATPase activity
BTK_RS26655	COG1464	Belongs to the NlpA lipoprotein family
BTK_RS26660	COG1464	Belongs to the NlpA lipoprotein family
BTK_RS26665	COG2011	ABC-type metal ion transport system permease component
BTK_RS26680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTK_RS26685	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BTK_RS26695	COG1393	Belongs to the ArsC family
BTK_RS26715	COG0039	L-malate dehydrogenase activity
BTK_RS26730	COG1309	transcriptional regulator
BTK_RS26735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTK_RS26740	COG1960	acyl-CoA dehydrogenase activity
BTK_RS26745	COG0183	Belongs to the thiolase family
BTK_RS26750	COG1024	Enoyl-CoA hydratase
BTK_RS26750	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTK_RS26760	COG1686	Belongs to the peptidase S11 family
BTK_RS26775	COG0011	TIGRFAM Protein of
BTK_RS26780	COG0840	transmembrane signaling receptor activity
BTK_RS26795	COG2814	Major facilitator Superfamily
BTK_RS26800	COG0531	amino acid
BTK_RS26820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTK_RS26855	COG0586	Pfam SNARE associated Golgi protein
BTK_RS26865	COG1376	ErfK ybiS ycfS ynhG family protein
BTK_RS26870	COG0745	RESPONSE REGULATOR receiver
BTK_RS26875	COG5002	protein histidine kinase activity
BTK_RS26905	COG0840	transmembrane signaling receptor activity
BTK_RS26910	COG2151	metal-sulfur cluster biosynthetic enzyme
BTK_RS26915	COG3227	Zinc metalloprotease (Elastase)
BTK_RS26935	COG0586	Pfam SNARE associated Golgi protein
BTK_RS26940	COG0475	glutathione-regulated potassium exporter activity
BTK_RS26945	COG0490	domain, Protein
BTK_RS26955	COG1115	amino acid carrier protein
BTK_RS26960	COG0783	Belongs to the Dps family
BTK_RS26985	COG1611	Belongs to the LOG family
BTK_RS26995	COG1528	Iron-storage protein
BTK_RS27000	COG2311	Membrane
BTK_RS27005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTK_RS27010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTK_RS27025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTK_RS27030	COG1115	amino acid carrier protein
BTK_RS27035	COG1115	amino acid carrier protein
BTK_RS27040	COG1115	amino acid carrier protein
BTK_RS27045	COG2910	NAD(P)H-binding
BTK_RS27060	COG0656	L-ascorbic acid biosynthetic process
BTK_RS27065	COG2814	Major facilitator Superfamily
BTK_RS27070	COG1733	regulation of RNA biosynthetic process
BTK_RS27080	COG1252	NADH dehydrogenase
BTK_RS27135	COG0488	(ABC) transporter
BTK_RS27140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTK_RS27190	COG0745	RESPONSE REGULATOR receiver
BTK_RS27205	COG3344	reverse transcriptase
BTK_RS27230	COG0557	exoribonuclease II activity
BTK_RS27235	COG1647	Serine aminopeptidase, S33
BTK_RS27240	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTK_RS27245	COG0557	exoribonuclease II activity
BTK_RS27260	COG0557	exoribonuclease II activity
BTK_RS27265	COG1647	Serine aminopeptidase, S33
BTK_RS27270	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTK_RS27275	COG1346	cytolysis
BTK_RS27310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTK_RS27325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BTK_RS27350	COG0457	Tetratricopeptide repeat
BTK_RS27355	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTK_RS27355	COG3409	Peptidoglycan-binding domain 1 protein
BTK_RS27355	COG1388	LysM domain
BTK_RS27365	COG4824	toxin secretion phage lysis holin
BTK_RS27410	COG0582	viral genome integration into host DNA
BTK_RS27435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTK_RS27450	COG2323	membrane
BTK_RS27460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTK_RS27470	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BTK_RS27480	COG1051	belongs to the nudix hydrolase family
BTK_RS27490	COG0492	ferredoxin-NADP+ reductase activity
BTK_RS27495	COG0457	Tetratricopeptide repeat
BTK_RS27500	COG0110	maltose O-acetyltransferase activity
BTK_RS27520	COG1950	PFAM Membrane protein of
BTK_RS27530	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BTK_RS27535	COG0556	nucleotide-excision repair
BTK_RS27550	COG0789	Transcriptional regulator
BTK_RS27570	COG0583	DNA-binding transcription factor activity
BTK_RS27580	COG0655	NAD(P)H dehydrogenase (quinone) activity
BTK_RS27585	COG0488	(ABC) transporter
BTK_RS27595	COG1132	(ABC) transporter
BTK_RS27600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTK_RS27605	COG0793	Belongs to the peptidase S41A family
BTK_RS27605	COG3409	Peptidoglycan-binding domain 1 protein
BTK_RS27610	COG2177	Part of the ABC transporter FtsEX involved in
BTK_RS27615	COG2884	Cell division ATP-binding protein ftsE
BTK_RS27630	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BTK_RS27650	COG1131	(ABC) transporter
BTK_RS27680	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BTK_RS27685	COG1278	Cold shock
BTK_RS27690	COG1040	competence protein
BTK_RS27695	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BTK_RS27700	COG0791	NLP P60 protein
BTK_RS27700	COG1388	LysM domain
BTK_RS27705	COG1733	regulation of RNA biosynthetic process
BTK_RS27710	COG1307	EDD domain protein, DegV family
BTK_RS27715	COG1739	Uncharacterized protein family UPF0029
BTK_RS27720	COG1316	TRANSCRIPTIONal
BTK_RS27725	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BTK_RS27730	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BTK_RS27735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTK_RS27765	COG1486	melibiose metabolic process
BTK_RS27770	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTK_RS27775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTK_RS27785	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTK_RS27795	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTK_RS27800	COG1301	dicarboxylic acid transport
BTK_RS27815	COG1511	domain protein
BTK_RS27820	COG0583	DNA-binding transcription factor activity
BTK_RS27825	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BTK_RS27835	COG1271	oxidase subunit
BTK_RS27840	COG1294	oxidase, subunit
BTK_RS27845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTK_RS27855	COG1620	l-lactate permease
BTK_RS27870	COG2389	metal-binding protein
BTK_RS27880	COG1368	sulfuric ester hydrolase activity
BTK_RS27890	COG1388	LysM domain
BTK_RS27890	COG0791	NLP P60 protein
BTK_RS27895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTK_RS27905	COG1215	transferase activity, transferring glycosyl groups
BTK_RS27915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTK_RS27920	COG1388	LysM domain
BTK_RS27920	COG3584	3D domain protein
BTK_RS27945	COG4715	Zinc finger, swim domain protein
BTK_RS27950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTK_RS27990	COG0577	efflux transmembrane transporter activity
BTK_RS27995	COG1136	(ABC) transporter
BTK_RS28025	COG0745	RESPONSE REGULATOR receiver
BTK_RS28035	COG1316	TRANSCRIPTIONal
BTK_RS28045	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BTK_RS28050	COG1215	transferase activity, transferring glycosyl groups
BTK_RS28055	COG0463	Glycosyl transferase, family 2
BTK_RS28060	COG0438	transferase activity, transferring glycosyl groups
BTK_RS28070	COG1216	Glycosyl transferase, family 2
BTK_RS28085	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTK_RS28090	COG4464	protein tyrosine phosphatase activity
BTK_RS28095	COG0489	protein tyrosine kinase activity
BTK_RS28100	COG3944	biosynthesis protein
BTK_RS28105	COG0489	protein tyrosine kinase activity
BTK_RS28120	COG1609	Transcriptional regulator
BTK_RS28130	COG0739	heme binding
BTK_RS28145	COG3279	Response regulator of the LytR AlgR family
BTK_RS28150	COG2385	sporulation resulting in formation of a cellular spore
BTK_RS28165	COG4836	Membrane
BTK_RS28170	COG1007	ATP synthesis coupled electron transport
BTK_RS28175	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTK_RS28180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTK_RS28185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTK_RS28195	COG0839	Belongs to the complex I subunit 6 family
BTK_RS28215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTK_RS28280	COG0356	it plays a direct role in the translocation of protons across the membrane
BTK_RS28315	COG0698	ribose 5-phosphate isomerase
BTK_RS28330	COG2259	Doxx family
BTK_RS28335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTK_RS28355	COG0009	L-threonylcarbamoyladenylate synthase
BTK_RS28390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BTK_RS28395	COG1494	fructose-1,6-bisphosphatase
BTK_RS28415	COG4821	SIS domain
BTK_RS28425	COG3343	RNA polymerase activity
BTK_RS28435	COG1960	acyl-CoA dehydrogenase activity
BTK_RS28440	COG1960	acyl-CoA dehydrogenase activity
BTK_RS28445	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTK_RS28450	COG0183	Belongs to the thiolase family
BTK_RS28455	COG0183	Belongs to the thiolase family
BTK_RS28460	COG0247	lactate metabolic process
BTK_RS28460	COG2181	nitrate reductase activity
BTK_RS28465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTK_RS28475	COG0183	Belongs to the thiolase family
BTK_RS28480	COG1960	acyl-CoA dehydrogenase activity
BTK_RS28485	COG1960	acyl-CoA dehydrogenase activity
BTK_RS28490	COG1960	acyl-CoA dehydrogenase activity
BTK_RS28495	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTK_RS28500	COG0183	Belongs to the thiolase family
BTK_RS28505	COG0247	lactate metabolic process
BTK_RS28505	COG2181	nitrate reductase activity
BTK_RS28510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTK_RS28525	COG3344	reverse transcriptase
BTK_RS28545	COG5001	Diguanylate cyclase
BTK_RS28545	COG3300	MHYT domain
BTK_RS28560	COG3227	Zinc metalloprotease (Elastase)
BTK_RS28565	COG2197	response regulator
BTK_RS28570	COG4585	Histidine kinase
BTK_RS28575	COG0842	Transport permease protein
BTK_RS28580	COG1131	(ABC) transporter
BTK_RS28585	COG0024	Methionine aminopeptidase
BTK_RS28595	COG2234	aminopeptidase activity
BTK_RS28600	COG2801	Transposase and inactivated derivatives
BTK_RS28625	COG1595	DNA-templated transcription, initiation
BTK_RS28635	COG4506	Protein conserved in bacteria
BTK_RS28640	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTK_RS28670	COG2814	Major facilitator Superfamily
BTK_RS28675	COG0789	Transcriptional regulator
BTK_RS28680	COG0584	glycerophosphoryl diester phosphodiesterase
BTK_RS28685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTK_RS28695	COG1994	Peptidase M50
BTK_RS28705	COG1078	dGTPase activity
BTK_RS28710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTK_RS28715	COG1120	ATPase activity
BTK_RS28720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTK_RS28725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTK_RS28745	COG0280	phosphate acetyltransferase
BTK_RS28760	COG3773	Cell wall hydrolase
BTK_RS28770	COG2363	Small membrane protein
BTK_RS28780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTK_RS28785	COG2233	PERMEase
BTK_RS28790	COG0561	phosphatase activity
BTK_RS28795	COG2814	Major facilitator Superfamily
BTK_RS28805	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BTK_RS28810	COG1131	(ABC) transporter
BTK_RS28815	COG2755	lipolytic protein G-D-S-L family
BTK_RS28820	COG1609	Transcriptional regulator
BTK_RS28830	COG0460	homoserine dehydrogenase
BTK_RS28840	COG2873	o-acetylhomoserine
BTK_RS28850	COG1011	Hydrolase
BTK_RS28855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTK_RS28865	COG2197	response regulator
BTK_RS28870	COG2203	Gaf domain
BTK_RS28870	COG4585	Histidine kinase
BTK_RS28875	COG0351	phosphomethylpyrimidine kinase
BTK_RS28880	COG3706	GGDEF domain
BTK_RS28885	COG2879	small protein
BTK_RS28890	COG1966	Carbon starvation protein
BTK_RS28895	COG3279	Response regulator of the LytR AlgR family
BTK_RS28900	COG0477	Major facilitator Superfamily
BTK_RS28910	COG0438	transferase activity, transferring glycosyl groups
BTK_RS28920	COG0840	transmembrane signaling receptor activity
BTK_RS28930	COG0840	transmembrane signaling receptor activity
BTK_RS28940	COG1607	acyl-coa hydrolase
BTK_RS28945	COG1216	Glycosyl transferase, family 2
BTK_RS28960	COG1216	Glycosyl transferase, family 2
BTK_RS28970	COG4485	Bacterial membrane protein, YfhO
BTK_RS28975	COG0463	Glycosyl transferase, family 2
BTK_RS28980	COG0488	(ABC) transporter
BTK_RS28985	COG1309	transcriptional regulator
BTK_RS28990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTK_RS28995	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTK_RS28995	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTK_RS29000	COG0628	permease
BTK_RS29020	COG3275	phosphorelay sensor kinase activity
BTK_RS29025	COG2814	Major facilitator Superfamily
BTK_RS29030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTK_RS29035	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BTK_RS29065	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTK_RS29070	COG1272	protein, Hemolysin III
BTK_RS29085	COG1272	protein, Hemolysin III
BTK_RS29105	COG3344	reverse transcriptase
BTK_RS29145	COG5002	protein histidine kinase activity
BTK_RS29160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTK_RS29165	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BTK_RS29170	COG4853	Protein conserved in bacteria
BTK_RS29180	COG5002	protein histidine kinase activity
BTK_RS29185	COG0745	RESPONSE REGULATOR receiver
BTK_RS29215	COG0305	Participates in initiation and elongation during chromosome replication
BTK_RS29225	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BTK_RS29230	COG4241	membrane
BTK_RS29250	COG0012	GTP binding
BTK_RS29255	COG4481	Protein conserved in bacteria
BTK_RS29260	COG0668	transmembrane transport
BTK_RS29270	COG1475	DNA binding
BTK_RS29300	COG1847	R3H domain protein
BTK_RS29315	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BTK_RS29335	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTK_RS29615	COG0470	DNA polymerase III
BTK_RS29645	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BTK_RS29665	COG0592	DNA-directed DNA polymerase activity
BTK_RS29670	COG0592	DNA-directed DNA polymerase activity
BTK_RS29825	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTK_RS29835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTK_RS29905	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BTK_RS30080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTK_RS30335	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTK_RS30720	COG0592	DNA-directed DNA polymerase activity
BTK_RS30980	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BTK_RS31025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BTK_RS31030	COG0251	oxidation-reduction process
BTK_RS31155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTK_RS31190	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BTK_RS31700	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BTK_RS31935	COG0489	protein tyrosine kinase activity
BTK_RS32055	COG1028	Short-chain dehydrogenase reductase Sdr
BTK_RS32115	COG2814	Major facilitator Superfamily
BTK_RS32245	COG0747	negative chemotaxis
BTK_RS32250	COG0747	negative chemotaxis
BTK_RS32650	COG1982	Orn Lys Arg decarboxylase major
BTK_RS32690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTK_RS32695	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTK_RS32900	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BTK_RS33475	COG2183	response to ionizing radiation
BTK_RS34080	COG0210	DNA helicase
BTK_RS34100	COG4851	CamS sex pheromone cAM373 precursor
BTK_RS34305	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTK_RS34360	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTK_RS34365	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTK_RS34375	COG0592	DNA-directed DNA polymerase activity
BTK_RS34400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTK_RS34430	COG0187	DNA topoisomerase II activity
BTK_RS34435	COG0187	DNA topoisomerase II activity
BTK_RS34440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTK_RS34490	COG0187	DNA topoisomerase II activity
BTK_RS34500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTK_RS34585	COG0187	DNA topoisomerase II activity
BTK_RS34595	COG0187	DNA topoisomerase II activity
BTK_RS34605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTK_RS34620	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTK_RS34660	COG2376	Dihydroxyacetone kinase