locus-tag	class	description
O3S71_RS00005	COG1802	Transcriptional regulator
O3S71_RS00005	COG4626	Terminase
O3S71_RS00015	COG0740	serine-type endopeptidase activity
O3S71_RS00080	COG4824	toxin secretion phage lysis holin
O3S71_RS00085	COG1388	LysM domain
O3S71_RS00085	COG3409	Peptidoglycan-binding domain 1 protein
O3S71_RS00085	COG5632	N-Acetylmuramoyl-L-alanine amidase
O3S71_RS00105	COG1674	ftsk spoiiie
O3S71_RS00120	COG0557	exoribonuclease II activity
O3S71_RS00165	COG2233	PERMEase
O3S71_RS00170	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
O3S71_RS00175	COG0288	reversible hydration of carbon dioxide
O3S71_RS00180	COG1522	sequence-specific DNA binding
O3S71_RS00190	COG1522	sequence-specific DNA binding
O3S71_RS00195	COG1335	isochorismatase
O3S71_RS00215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O3S71_RS00220	COG0488	(ABC) transporter
O3S71_RS00255	COG3290	protein histidine kinase activity
O3S71_RS00255	COG0840	transmembrane signaling receptor activity
O3S71_RS00275	COG1252	NADH dehydrogenase
O3S71_RS00285	COG1733	regulation of RNA biosynthetic process
O3S71_RS00290	COG2814	Major facilitator Superfamily
O3S71_RS00295	COG0656	L-ascorbic acid biosynthetic process
O3S71_RS00310	COG2910	NAD(P)H-binding
O3S71_RS00315	COG1115	amino acid carrier protein
O3S71_RS00320	COG1115	amino acid carrier protein
O3S71_RS00325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O3S71_RS00330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O3S71_RS00335	COG2311	Membrane
O3S71_RS00350	COG1611	Belongs to the LOG family
O3S71_RS00370	COG0783	Belongs to the Dps family
O3S71_RS00375	COG1115	amino acid carrier protein
O3S71_RS00380	COG0490	domain, Protein
O3S71_RS00385	COG0475	glutathione-regulated potassium exporter activity
O3S71_RS00390	COG0586	Pfam SNARE associated Golgi protein
O3S71_RS00410	COG3227	Zinc metalloprotease (Elastase)
O3S71_RS00415	COG2151	metal-sulfur cluster biosynthetic enzyme
O3S71_RS00420	COG0840	transmembrane signaling receptor activity
O3S71_RS00450	COG5002	protein histidine kinase activity
O3S71_RS00455	COG0745	RESPONSE REGULATOR receiver
O3S71_RS00460	COG1376	ErfK ybiS ycfS ynhG family protein
O3S71_RS00470	COG0586	Pfam SNARE associated Golgi protein
O3S71_RS00510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O3S71_RS00535	COG0531	amino acid
O3S71_RS00540	COG2814	Major facilitator Superfamily
O3S71_RS00555	COG0840	transmembrane signaling receptor activity
O3S71_RS00560	COG0011	TIGRFAM Protein of
O3S71_RS00575	COG1686	Belongs to the peptidase S11 family
O3S71_RS00585	COG1250	3-hydroxyacyl-CoA dehydrogenase
O3S71_RS00585	COG1024	Enoyl-CoA hydratase
O3S71_RS00590	COG0183	Belongs to the thiolase family
O3S71_RS00595	COG1960	acyl-CoA dehydrogenase activity
O3S71_RS00600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O3S71_RS00615	COG0039	L-malate dehydrogenase activity
O3S71_RS00635	COG1393	Belongs to the ArsC family
O3S71_RS00645	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
O3S71_RS00650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O3S71_RS00665	COG2011	ABC-type metal ion transport system permease component
O3S71_RS00670	COG1464	Belongs to the NlpA lipoprotein family
O3S71_RS00675	COG1464	Belongs to the NlpA lipoprotein family
O3S71_RS00680	COG0396	ATPase activity
O3S71_RS00685	COG0719	Fe-S assembly protein
O3S71_RS00690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
O3S71_RS00695	COG0822	iron-sulfur transferase activity
O3S71_RS00700	COG0719	Fe-S assembly protein
O3S71_RS00705	COG0737	Belongs to the 5'-nucleotidase family
O3S71_RS00710	COG3377	Domain of unknown function (DUF1805)
O3S71_RS00720	COG0739	heme binding
O3S71_RS00745	COG4377	Putative membrane peptidase family (DUF2324)
O3S71_RS00750	COG0789	Transcriptional regulator
O3S71_RS00760	COG4470	Protein conserved in bacteria
O3S71_RS00775	COG1494	fructose-1,6-bisphosphatase
O3S71_RS00780	COG2445	Protein of unknown function DUF86
O3S71_RS00790	COG0647	UMP catabolic process
O3S71_RS00795	COG2249	NAD(P)H dehydrogenase (quinone) activity
O3S71_RS00810	COG1358	cellular component organization or biogenesis
O3S71_RS00830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
O3S71_RS00835	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
O3S71_RS00845	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
O3S71_RS00850	COG4837	Protein of unknown function (DUF1462)
O3S71_RS00875	COG2824	Alkylphosphonate utilization operon protein PhnA
O3S71_RS00880	COG0390	transport system, permease component
O3S71_RS00885	COG2274	protein secretion by the type I secretion system
O3S71_RS00895	COG1252	NADH dehydrogenase
O3S71_RS00910	COG0316	Belongs to the HesB IscA family
O3S71_RS00945	COG1683	Conserved Protein
O3S71_RS00960	COG3708	Transcriptional regulator
O3S71_RS00975	COG1252	NADH dehydrogenase
O3S71_RS00990	COG3584	3D domain protein
O3S71_RS01005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
O3S71_RS01010	COG1210	Utp--glucose-1-phosphate uridylyltransferase
O3S71_RS01015	COG1268	BioY protein
O3S71_RS01025	COG2050	protein possibly involved in aromatic compounds catabolism
O3S71_RS01045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
O3S71_RS01050	COG5018	Exonuclease
O3S71_RS01075	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
O3S71_RS01085	COG2267	carboxylic ester hydrolase activity
O3S71_RS01090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
O3S71_RS01095	COG1522	sequence-specific DNA binding
O3S71_RS01100	COG0436	Aminotransferase
O3S71_RS01105	COG1098	S1 RNA binding domain
O3S71_RS01110	COG2155	Conserved Protein
O3S71_RS01125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
O3S71_RS01130	COG1285	pathogenesis
O3S71_RS01265	COG1309	transcriptional regulator
O3S71_RS01290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
O3S71_RS01295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
O3S71_RS01305	COG0058	SHG alpha-glucan phosphorylase activity
O3S71_RS01330	COG1278	Cold shock
O3S71_RS01335	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
O3S71_RS01340	COG1575	Belongs to the MenA family. Type 1 subfamily
O3S71_RS01345	COG1169	isochorismate synthase
O3S71_RS01355	COG0596	Alpha beta hydrolase
O3S71_RS01360	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
O3S71_RS01370	COG4948	Mandelate Racemase Muconate Lactonizing
O3S71_RS01390	COG3964	amidohydrolase
O3S71_RS01410	COG2188	Transcriptional regulator
O3S71_RS01425	COG0577	efflux transmembrane transporter activity
O3S71_RS01430	COG1136	(ABC) transporter
O3S71_RS01435	COG0577	efflux transmembrane transporter activity
O3S71_RS01440	COG0577	efflux transmembrane transporter activity
O3S71_RS01445	COG2205	protein histidine kinase activity
O3S71_RS01450	COG0745	RESPONSE REGULATOR receiver
O3S71_RS01460	COG0640	Transcriptional regulator
O3S71_RS01465	COG5658	integral membrane protein
O3S71_RS01470	COG1131	(ABC) transporter
O3S71_RS01480	COG2207	Transcriptional regulator
O3S71_RS01480	COG3708	Transcriptional regulator
O3S71_RS01485	COG1136	(ABC) transporter
O3S71_RS01490	COG0577	efflux transmembrane transporter activity
O3S71_RS01500	COG0586	Pfam SNARE associated Golgi protein
O3S71_RS01550	COG1597	lipid kinase activity
O3S71_RS01555	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
O3S71_RS01580	COG0745	RESPONSE REGULATOR receiver
O3S71_RS01585	COG5002	protein histidine kinase activity
O3S71_RS01590	COG3859	Proton-coupled thiamine transporter YuaJ
O3S71_RS01615	COG1842	Phage shock protein A
O3S71_RS01640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O3S71_RS01660	COG1294	oxidase, subunit
O3S71_RS01665	COG1271	oxidase subunit
O3S71_RS01670	COG0288	reversible hydration of carbon dioxide
O3S71_RS01680	COG1854	S-ribosylhomocysteine lyase activity
O3S71_RS01685	COG0789	Transcriptional regulator
O3S71_RS01690	COG2076	Multidrug Resistance protein
O3S71_RS01695	COG2076	Multidrug Resistance protein
O3S71_RS01725	COG0494	nUDIX hydrolase
O3S71_RS01750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
O3S71_RS01755	COG1116	anion transmembrane transporter activity
O3S71_RS01760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
O3S71_RS01775	COG1368	sulfuric ester hydrolase activity
O3S71_RS01780	COG2267	carboxylic ester hydrolase activity
O3S71_RS01800	COG3852	Histidine kinase
O3S71_RS01805	COG5002	protein histidine kinase activity
O3S71_RS01900	COG0438	transferase activity, transferring glycosyl groups
O3S71_RS01905	COG0671	phosphoesterase, PA-phosphatase related
O3S71_RS01910	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
O3S71_RS01915	COG2267	carboxylic ester hydrolase activity
O3S71_RS01930	COG1794	racemase activity, acting on amino acids and derivatives
O3S71_RS01935	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
O3S71_RS01940	COG1242	4 iron, 4 sulfur cluster binding
O3S71_RS01960	COG1136	(ABC) transporter
O3S71_RS01970	COG0582	viral genome integration into host DNA
O3S71_RS01975	COG0490	domain, Protein
O3S71_RS01980	COG0475	glutathione-regulated potassium exporter activity
O3S71_RS01985	COG2814	Major facilitator Superfamily
O3S71_RS02025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
O3S71_RS02035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
O3S71_RS02055	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
O3S71_RS02060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
O3S71_RS02070	COG0303	'Molybdopterin
O3S71_RS02075	COG1763	Mo-molybdopterin cofactor biosynthetic process
O3S71_RS02080	COG0314	molybdopterin synthase activity
O3S71_RS02105	COG1329	Transcriptional regulator
O3S71_RS02125	COG3832	glyoxalase III activity
O3S71_RS02135	COG2814	Major facilitator Superfamily
O3S71_RS02140	COG2081	HI0933 family
O3S71_RS02145	COG2244	polysaccharide biosynthetic process
O3S71_RS02150	COG1187	pseudouridine synthase activity
O3S71_RS02155	COG1349	DNA-binding transcription factor activity
O3S71_RS02160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O3S71_RS02170	COG1523	belongs to the glycosyl hydrolase 13 family
O3S71_RS02175	COG0510	thiamine kinase activity
O3S71_RS02190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O3S71_RS02200	COG1363	Peptidase, m42
O3S71_RS02205	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
O3S71_RS02210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O3S71_RS02220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O3S71_RS02235	COG1674	ftsk spoiiie
O3S71_RS02250	COG0789	Transcriptional regulator
O3S71_RS02255	COG0697	spore germination
O3S71_RS02260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O3S71_RS02290	COG3118	belongs to the thioredoxin family
O3S71_RS02295	COG4851	CamS sex pheromone cAM373 precursor
O3S71_RS02310	COG1609	Transcriptional regulator
O3S71_RS02345	COG0666	response to abiotic stimulus
O3S71_RS02350	COG5002	protein histidine kinase activity
O3S71_RS02355	COG0745	RESPONSE REGULATOR receiver
O3S71_RS02370	COG0123	including yeast histone deacetylase and acetoin utilization protein
O3S71_RS02375	COG0517	IMP dehydrogenase activity
O3S71_RS02380	COG0454	-acetyltransferase
O3S71_RS02385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
O3S71_RS02390	COG0110	maltose O-acetyltransferase activity
O3S71_RS02425	COG0626	cystathionine gamma-synthase activity
O3S71_RS02430	COG1956	GAF domain-containing protein
O3S71_RS02435	COG1309	transcriptional regulator
O3S71_RS02440	COG0697	spore germination
O3S71_RS02445	COG0583	DNA-binding transcription factor activity
O3S71_RS02455	COG1104	cysteine desulfurase activity
O3S71_RS02470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
O3S71_RS02480	COG1574	metal-dependent hydrolase with the TIM-barrel fold
O3S71_RS02495	COG3874	Sporulation protein YtfJ
O3S71_RS02500	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
O3S71_RS02505	COG0827	DNA restriction-modification system
O3S71_RS02530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O3S71_RS02570	COG0589	response to stress
O3S71_RS02575	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS02590	COG0662	Cupin 2, conserved barrel domain protein
O3S71_RS02595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O3S71_RS02640	COG0006	proline dipeptidase activity
O3S71_RS02655	COG4109	DRTGG domain
O3S71_RS02670	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
O3S71_RS02685	COG0587	DNA-directed DNA polymerase activity
O3S71_RS02690	COG0281	malic enzyme
O3S71_RS02695	COG1725	Transcriptional regulator
O3S71_RS02720	COG3030	protein affecting phage T7 exclusion by the F plasmid
O3S71_RS02725	COG0628	permease
O3S71_RS02735	COG0372	Belongs to the citrate synthase family
O3S71_RS02740	COG0538	isocitrate dehydrogenase activity
O3S71_RS02765	COG0745	RESPONSE REGULATOR receiver
O3S71_RS02770	COG5002	protein histidine kinase activity
O3S71_RS02775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
O3S71_RS02775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
O3S71_RS02785	COG1971	Probably functions as a manganese efflux pump
O3S71_RS02790	COG0237	dephospho-CoA kinase activity
O3S71_RS02795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
O3S71_RS02800	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
O3S71_RS02810	COG3611	Membrane attachment protein
O3S71_RS02815	COG1484	DNA-dependent DNA replication
O3S71_RS02830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
O3S71_RS02855	COG1363	Peptidase, m42
O3S71_RS02860	COG1309	transcriptional regulator
O3S71_RS02865	COG1566	PFAM secretion protein HlyD family protein
O3S71_RS02870	COG2814	Major facilitator Superfamily
O3S71_RS02885	COG1418	mRNA catabolic process
O3S71_RS02895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
O3S71_RS02935	COG1286	toxin biosynthetic process
O3S71_RS02940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
O3S71_RS02940	COG1796	DNA polymerase
O3S71_RS02950	COG1187	pseudouridine synthase activity
O3S71_RS02955	COG1114	Component of the transport system for branched-chain amino acids
O3S71_RS02960	COG5386	Cell surface protein
O3S71_RS02970	COG5386	Cell surface protein
O3S71_RS02985	COG1120	ATPase activity
O3S71_RS02990	COG4509	Sortase family
O3S71_RS03000	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
O3S71_RS03005	COG4895	conserved protein (DUF2196)
O3S71_RS03015	COG0745	RESPONSE REGULATOR receiver
O3S71_RS03020	COG2205	protein histidine kinase activity
O3S71_RS03025	COG1131	(ABC) transporter
O3S71_RS03045	COG2318	DinB family
O3S71_RS03070	COG0318	PFAM AMP-dependent synthetase and ligase
O3S71_RS03075	COG1309	transcriptional regulator
O3S71_RS03080	COG1024	Enoyl-CoA hydratase
O3S71_RS03085	COG2086	electron transfer activity
O3S71_RS03090	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
O3S71_RS03095	COG3118	belongs to the thioredoxin family
O3S71_RS03105	COG1719	4-vinyl reductase, 4VR
O3S71_RS03110	COG2009	succinate dehydrogenase
O3S71_RS03115	COG1053	succinate dehydrogenase
O3S71_RS03120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
O3S71_RS03125	COG0824	Thioesterase
O3S71_RS03130	COG1876	peptidase activity
O3S71_RS03135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
O3S71_RS03140	COG1360	Flagellar Motor Protein
O3S71_RS03145	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
O3S71_RS03150	COG4152	abc transporter atp-binding protein
O3S71_RS03155	COG1668	transmembrane transport
O3S71_RS03160	COG1959	2 iron, 2 sulfur cluster binding
O3S71_RS03170	COG0697	spore germination
O3S71_RS03175	COG1396	sequence-specific DNA binding
O3S71_RS03180	COG1983	PspC domain protein
O3S71_RS03185	COG0402	S-adenosylhomocysteine deaminase activity
O3S71_RS03190	COG2233	PERMEase
O3S71_RS03195	COG2197	response regulator
O3S71_RS03205	COG1396	sequence-specific DNA binding
O3S71_RS03205	COG3800	Transcriptional regulator
O3S71_RS03350	COG1802	Transcriptional regulator
O3S71_RS03350	COG4626	Terminase
O3S71_RS03430	COG5632	N-Acetylmuramoyl-L-alanine amidase
O3S71_RS03500	COG1309	transcriptional regulator
O3S71_RS03520	COG5401	PFAM Sporulation and spore germination
O3S71_RS03535	COG0622	Phosphoesterase
O3S71_RS03580	COG0470	DNA polymerase III
O3S71_RS03580	COG1067	ATP-dependent peptidase activity
O3S71_RS03595	COG1764	response to oxidative stress
O3S71_RS03600	COG1846	Transcriptional regulator
O3S71_RS03610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
O3S71_RS03620	COG1587	Uroporphyrinogen-III synthase
O3S71_RS03625	COG0113	porphobilinogen synthase activity
O3S71_RS03635	COG1388	LysM domain
O3S71_RS03650	COG0285	dihydrofolate synthase activity
O3S71_RS03670	COG1077	Cell shape determining protein MreB Mrl
O3S71_RS03690	COG2894	cell division
O3S71_RS03695	COG0739	heme binding
O3S71_RS03700	COG1994	Peptidase M50
O3S71_RS03705	COG1530	ribonuclease E activity
O3S71_RS03715	COG2868	ribosomal protein
O3S71_RS03725	COG3290	protein histidine kinase activity
O3S71_RS03735	COG0745	RESPONSE REGULATOR receiver
O3S71_RS03740	COG5002	protein histidine kinase activity
O3S71_RS03745	COG1136	(ABC) transporter
O3S71_RS03750	COG0577	efflux transmembrane transporter activity
O3S71_RS03755	COG0577	efflux transmembrane transporter activity
O3S71_RS03760	COG0077	Prephenate dehydratase
O3S71_RS03770	COG2258	MOSC domain
O3S71_RS03775	COG1827	regulation of RNA biosynthetic process
O3S71_RS03780	COG1104	cysteine desulfurase activity
O3S71_RS03785	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
O3S71_RS03790	COG0157	Belongs to the NadC ModD family
O3S71_RS03825	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
O3S71_RS03855	COG1862	Preprotein translocase
O3S71_RS03865	COG2323	membrane
O3S71_RS03870	COG2244	polysaccharide biosynthetic process
O3S71_RS03880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
O3S71_RS03880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
O3S71_RS03885	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
O3S71_RS03890	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
O3S71_RS03890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
O3S71_RS03900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
O3S71_RS03930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
O3S71_RS03940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
O3S71_RS03945	COG1959	2 iron, 2 sulfur cluster binding
O3S71_RS03950	COG1104	cysteine desulfurase activity
O3S71_RS03965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
O3S71_RS03985	COG0628	permease
O3S71_RS04000	COG4472	Bacterial protein of unknown function (DUF965)
O3S71_RS04015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
O3S71_RS04020	COG4122	O-methyltransferase activity
O3S71_RS04025	COG0826	peptidase U32
O3S71_RS04030	COG0826	peptidase U32
O3S71_RS04050	COG0768	penicillin binding
O3S71_RS04075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
O3S71_RS04080	COG0626	cystathionine gamma-synthase activity
O3S71_RS04085	COG1012	belongs to the aldehyde dehydrogenase family
O3S71_RS04085	COG1454	alcohol dehydrogenase
O3S71_RS04095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O3S71_RS04135	COG2259	Doxx family
O3S71_RS04140	COG2514	catechol 2,3-dioxygenase activity
O3S71_RS04150	COG3186	Phenylalanine-4-hydroxylase
O3S71_RS04155	COG1404	Belongs to the peptidase S8 family
O3S71_RS04190	COG2267	carboxylic ester hydrolase activity
O3S71_RS04200	COG1785	Belongs to the alkaline phosphatase family
O3S71_RS04210	COG2357	RelA SpoT domain protein
O3S71_RS04220	COG0778	Nitroreductase
O3S71_RS04230	COG1595	DNA-templated transcription, initiation
O3S71_RS04255	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
O3S71_RS04260	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
O3S71_RS04270	COG1534	Rna-binding protein
O3S71_RS04280	COG1713	HD superfamily hydrolase involved in NAD metabolism
O3S71_RS04285	COG0799	negative regulation of ribosome biogenesis
O3S71_RS04290	COG2226	methyltransferase
O3S71_RS04295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
O3S71_RS04300	COG1555	photosystem II stabilization
O3S71_RS04300	COG1596	polysaccharide export
O3S71_RS04305	COG2131	deaminase
O3S71_RS04310	COG0658	competence protein
O3S71_RS04310	COG2333	competence protein COMEC
O3S71_RS04320	COG1466	dna polymerase III delta subunit
O3S71_RS04345	COG1733	regulation of RNA biosynthetic process
O3S71_RS04350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
O3S71_RS04380	COG1385	rRNA (uridine-N3-)-methyltransferase activity
O3S71_RS04385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
O3S71_RS04390	COG0828	Belongs to the bacterial ribosomal protein bS21 family
O3S71_RS04395	COG1610	YqeY-like protein
O3S71_RS04415	COG1702	phosphate starvation-inducible protein PhoH
O3S71_RS04420	COG1480	7TM receptor with intracellular HD hydrolase
O3S71_RS04430	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
O3S71_RS04435	COG0295	cytidine deaminase activity
O3S71_RS04440	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
O3S71_RS04455	COG0517	IMP dehydrogenase activity
O3S71_RS04465	COG1671	Belongs to the UPF0178 family
O3S71_RS04470	COG1671	Belongs to the UPF0178 family
O3S71_RS04475	COG0358	DNA primase activity
O3S71_RS04480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
O3S71_RS04490	COG2384	SAM-dependent methyltransferase
O3S71_RS04495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
O3S71_RS04525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O3S71_RS04530	COG1121	(ABC) transporter
O3S71_RS04535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
O3S71_RS04540	COG0735	belongs to the Fur family
O3S71_RS04555	COG5521	maltodextrose utilization protein MalA
O3S71_RS04565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
O3S71_RS04570	COG0477	Major facilitator Superfamily
O3S71_RS04575	COG0768	penicillin binding
O3S71_RS04585	COG0573	inorganic phosphate transmembrane transporter activity
O3S71_RS04590	COG0573	inorganic phosphate transmembrane transporter activity
O3S71_RS04600	COG0704	Plays a role in the regulation of phosphate uptake
O3S71_RS04605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
O3S71_RS04610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
O3S71_RS04615	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
O3S71_RS04620	COG4483	Protein conserved in bacteria
O3S71_RS04625	COG1940	carbohydrate kinase activity
O3S71_RS04635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O3S71_RS04655	COG0626	cystathionine gamma-synthase activity
O3S71_RS04660	COG0626	cystathionine gamma-synthase activity
O3S71_RS04665	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
O3S71_RS04665	COG0646	methionine synthase
O3S71_RS04725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
O3S71_RS04730	COG1459	type II secretion system
O3S71_RS04800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
O3S71_RS04840	COG2076	Multidrug Resistance protein
O3S71_RS04845	COG2076	Multidrug Resistance protein
O3S71_RS04855	COG1609	Transcriptional regulator
O3S71_RS04865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
O3S71_RS04900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
O3S71_RS04910	COG3872	metal-dependent enzyme
O3S71_RS04925	COG0006	proline dipeptidase activity
O3S71_RS04950	COG3854	ATPases associated with a variety of cellular activities
O3S71_RS04995	COG0511	ligase activity, forming carbon-carbon bonds
O3S71_RS05000	COG0439	Biotin carboxylase
O3S71_RS05005	COG1302	Protein conserved in bacteria
O3S71_RS05030	COG0142	geranyltranstransferase activity
O3S71_RS05040	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
O3S71_RS05050	COG0497	DNA recombination
O3S71_RS05055	COG0750	zinc metalloprotease
O3S71_RS05070	COG3093	addiction module antidote protein HigA
O3S71_RS05075	COG0584	glycerophosphoryl diester phosphodiesterase
O3S71_RS05085	COG3290	protein histidine kinase activity
O3S71_RS05085	COG3829	transcription factor binding
O3S71_RS05090	COG0280	phosphate acetyltransferase
O3S71_RS05105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
O3S71_RS05110	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
O3S71_RS05115	COG0022	dehydrogenase e1 component
O3S71_RS05120	COG0508	dehydrogenase complex catalyzes the overall conversion of
O3S71_RS05125	COG0772	Belongs to the SEDS family
O3S71_RS05130	COG2323	membrane
O3S71_RS05150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O3S71_RS05155	COG0765	amino acid transport
O3S71_RS05160	COG1126	abc transporter atp-binding protein
O3S71_RS05165	COG4129	membrane
O3S71_RS05170	COG1376	ErfK ybiS ycfS ynhG family protein
O3S71_RS05185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O3S71_RS05190	COG2195	Cleaves the N-terminal amino acid of tripeptides
O3S71_RS05200	COG1285	pathogenesis
O3S71_RS05230	COG1760	l-serine dehydratase
O3S71_RS05235	COG1760	l-serine dehydratase
O3S71_RS05240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
O3S71_RS05245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O3S71_RS05250	COG0300	oxidoreductase activity
O3S71_RS05295	COG1522	sequence-specific DNA binding
O3S71_RS05305	COG0737	Belongs to the 5'-nucleotidase family
O3S71_RS05310	COG1757	Na H antiporter
O3S71_RS05320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
O3S71_RS05335	COG1073	alpha beta
O3S71_RS05335	COG2226	methyltransferase
O3S71_RS05365	COG0307	riboflavin synthase, alpha
O3S71_RS05370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
O3S71_RS05370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
O3S71_RS05385	COG1073	alpha beta
O3S71_RS05390	COG0456	acetyltransferase
O3S71_RS05395	COG1609	Transcriptional regulator
O3S71_RS05400	COG2056	Na+-H+ antiporter family
O3S71_RS05405	COG0596	Alpha beta hydrolase
O3S71_RS05415	COG0737	Belongs to the 5'-nucleotidase family
O3S71_RS05415	COG4085	toxin activity
O3S71_RS05415	COG1525	nuclease
O3S71_RS05425	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
O3S71_RS05425	COG0456	acetyltransferase
O3S71_RS05430	COG0656	L-ascorbic acid biosynthetic process
O3S71_RS05435	COG0667	Aldo Keto reductase
O3S71_RS05455	COG1300	Membrane
O3S71_RS05460	COG0735	belongs to the Fur family
O3S71_RS05470	COG4974	Belongs to the 'phage' integrase family
O3S71_RS05495	COG0598	Magnesium transport protein CorA
O3S71_RS05510	COG1846	Transcriptional regulator
O3S71_RS05535	COG1131	(ABC) transporter
O3S71_RS05540	COG1725	Transcriptional regulator
O3S71_RS05545	COG1686	Belongs to the peptidase S11 family
O3S71_RS05565	COG0733	neurotransmitter:sodium symporter activity
O3S71_RS05590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
O3S71_RS05605	COG0697	spore germination
O3S71_RS05610	COG0561	phosphatase activity
O3S71_RS05615	COG4086	secreted protein
O3S71_RS05620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
O3S71_RS05625	COG0456	acetyltransferase
O3S71_RS05630	COG1547	Domain of unknown function (DUF309)
O3S71_RS05655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
O3S71_RS05670	COG2188	Transcriptional regulator
O3S71_RS05680	COG3711	transcriptional antiterminator
O3S71_RS05685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O3S71_RS05685	COG2190	(PTS) system
O3S71_RS05685	COG1263	PTS System
O3S71_RS05710	COG0778	Nitroreductase
O3S71_RS05715	COG2199	diguanylate cyclase activity
O3S71_RS05725	COG2084	Dehydrogenase
O3S71_RS05760	COG0436	Aminotransferase
O3S71_RS05765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
O3S71_RS05785	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS05790	COG1695	Transcriptional regulator
O3S71_RS05825	COG0183	Belongs to the thiolase family
O3S71_RS05865	COG3842	ATPase activity
O3S71_RS05870	COG0366	Alpha amylase catalytic
O3S71_RS05880	COG2182	Extracellular solute-binding protein
O3S71_RS05885	COG1175	transmembrane transport
O3S71_RS05890	COG3833	ABC-type maltose transport systems, permease component
O3S71_RS05895	COG1609	Transcriptional regulator
O3S71_RS05900	COG0436	Aminotransferase
O3S71_RS05910	COG2205	protein histidine kinase activity
O3S71_RS05920	COG3209	COG3209 Rhs family protein
O3S71_RS05995	COG1408	metallophosphoesterase
O3S71_RS06000	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS06005	COG2200	EAL domain
O3S71_RS06020	COG4703	Protein of unknown function (DUF1797)
O3S71_RS06030	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
O3S71_RS06040	COG0517	IMP dehydrogenase activity
O3S71_RS06045	COG0583	DNA-binding transcription factor activity
O3S71_RS06065	COG0569	domain protein
O3S71_RS06070	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
O3S71_RS06080	COG0561	phosphatase activity
O3S71_RS06095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
O3S71_RS06100	COG0022	dehydrogenase e1 component
O3S71_RS06150	COG1982	Orn Lys Arg decarboxylase major
O3S71_RS06170	COG0483	inositol monophosphate 1-phosphatase activity
O3S71_RS06180	COG1217	gtp-binding protein TYPA
O3S71_RS06195	COG4896	Protein conserved in bacteria
O3S71_RS06205	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
O3S71_RS06210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
O3S71_RS06220	COG0772	Belongs to the SEDS family
O3S71_RS06225	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
O3S71_RS06260	COG3336	cytochrome c oxidase
O3S71_RS06275	COG2340	Cysteine-rich secretory protein family
O3S71_RS06290	COG0406	alpha-ribazole phosphatase activity
O3S71_RS06295	COG3679	Belongs to the UPF0342 family
O3S71_RS06310	COG0742	ribosomal rna small subunit methyltransferase
O3S71_RS06320	COG3314	Sporulation integral membrane protein YlbJ
O3S71_RS06325	COG1752	Esterase of the alpha-beta hydrolase superfamily
O3S71_RS06330	COG3480	Lon protease (S16) C-terminal proteolytic domain
O3S71_RS06340	COG1399	metal-binding, possibly nucleic acid-binding protein
O3S71_RS06345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
O3S71_RS06360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
O3S71_RS06380	COG0768	penicillin binding
O3S71_RS06385	COG0768	penicillin binding
O3S71_RS06405	COG0772	Belongs to the SEDS family
O3S71_RS06425	COG0849	cell division
O3S71_RS06430	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
O3S71_RS06440	COG1191	sigma factor activity
O3S71_RS06445	COG1191	sigma factor activity
O3S71_RS06450	COG1873	PFAM PRC-barrel domain
O3S71_RS06460	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
O3S71_RS06470	COG0762	integral membrane protein
O3S71_RS06475	COG2302	S4 RNA-binding domain
O3S71_RS06480	COG3599	regulation of cell shape
O3S71_RS06500	COG0564	pseudouridine synthase activity
O3S71_RS06560	COG3069	C4-dicarboxylate transmembrane transporter activity
O3S71_RS06590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
O3S71_RS06595	COG1561	YicC-like family, N-terminal region
O3S71_RS06615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
O3S71_RS06620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
O3S71_RS06635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
O3S71_RS06635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
O3S71_RS06645	COG0631	protein serine/threonine phosphatase activity
O3S71_RS06650	COG0515	serine threonine protein kinase
O3S71_RS06650	COG2815	serine threonine protein kinase
O3S71_RS06660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
O3S71_RS06665	COG1564	THIamine pyrophosphokinase
O3S71_RS06680	COG1302	Protein conserved in bacteria
O3S71_RS06685	COG1461	Dihydroxyacetone kinase
O3S71_RS06690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
O3S71_RS06705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
O3S71_RS06710	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS06715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O3S71_RS06725	COG1196	nuclear chromosome segregation
O3S71_RS06730	COG0552	protein localization to endoplasmic reticulum
O3S71_RS06740	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
O3S71_RS06750	COG1837	Belongs to the UPF0109 family
O3S71_RS06790	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
O3S71_RS06795	COG0758	DNA mediated transformation
O3S71_RS06800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
O3S71_RS06810	COG4974	Belongs to the 'phage' integrase family
O3S71_RS06855	COG4589	Belongs to the CDS family
O3S71_RS06865	COG0750	zinc metalloprotease
O3S71_RS06885	COG0195	Participates in both transcription termination and antitermination
O3S71_RS06890	COG2740	Nucleic-acid-binding protein implicated in transcription termination
O3S71_RS06895	COG1358	cellular component organization or biogenesis
O3S71_RS06905	COG1550	Protein conserved in bacteria
O3S71_RS06910	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
O3S71_RS06920	COG0196	riboflavin kinase activity
O3S71_RS06935	COG0726	polysaccharide deacetylase
O3S71_RS06940	COG0612	Peptidase, M16
O3S71_RS06945	COG1873	PFAM PRC-barrel domain
O3S71_RS06950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
O3S71_RS06975	COG1396	sequence-specific DNA binding
O3S71_RS07010	COG0305	Participates in initiation and elongation during chromosome replication
O3S71_RS07055	COG0582	viral genome integration into host DNA
O3S71_RS07060	COG1278	Cold shock
O3S71_RS07215	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
O3S71_RS07220	COG0527	aspartate kinase activity
O3S71_RS07230	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
O3S71_RS07235	COG0740	serine-type endopeptidase activity
O3S71_RS07250	COG2188	Transcriptional regulator
O3S71_RS07255	COG1744	ABC transporter substrate-binding protein PnrA-like
O3S71_RS07260	COG3845	ABC transporter
O3S71_RS07265	COG4603	Belongs to the binding-protein-dependent transport system permease family
O3S71_RS07270	COG1079	Belongs to the binding-protein-dependent transport system permease family
O3S71_RS07275	COG0612	Peptidase, M16
O3S71_RS07280	COG0612	Peptidase, M16
O3S71_RS07285	COG0300	oxidoreductase activity
O3S71_RS07300	COG1426	Protein conserved in bacteria
O3S71_RS07305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
O3S71_RS07325	COG1692	metallophosphoesterase
O3S71_RS07330	COG2359	stage V sporulation protein S
O3S71_RS07340	COG0674	pyruvate-flavodoxin oxidoreductase activity
O3S71_RS07340	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
O3S71_RS07345	COG1013	pyruvate-flavodoxin oxidoreductase activity
O3S71_RS07355	COG4550	Control of competence regulator ComK, YlbF/YmcA
O3S71_RS07395	COG1396	sequence-specific DNA binding
O3S71_RS07410	COG0840	transmembrane signaling receptor activity
O3S71_RS07450	COG1725	Transcriptional regulator
O3S71_RS07455	COG1131	(ABC) transporter
O3S71_RS07480	COG1131	(ABC) transporter
O3S71_RS07485	COG1132	(ABC) transporter
O3S71_RS07530	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
O3S71_RS07535	COG1368	sulfuric ester hydrolase activity
O3S71_RS07545	COG3773	Cell wall hydrolase
O3S71_RS07555	COG1404	Belongs to the peptidase S8 family
O3S71_RS07565	COG0840	transmembrane signaling receptor activity
O3S71_RS07580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O3S71_RS07590	COG1346	cytolysis
O3S71_RS07610	COG1086	Polysaccharide biosynthesis protein
O3S71_RS07630	COG3300	MHYT domain
O3S71_RS07630	COG5001	Diguanylate cyclase
O3S71_RS07635	COG2267	carboxylic ester hydrolase activity
O3S71_RS07650	COG2364	Membrane
O3S71_RS07660	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
O3S71_RS07665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
O3S71_RS07670	COG2169	Transcriptional regulator
O3S71_RS07675	COG0708	Exodeoxyribonuclease III
O3S71_RS07680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O3S71_RS07685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O3S71_RS07690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O3S71_RS07695	COG1120	ATPase activity
O3S71_RS07700	COG2819	hydrolase of the alpha beta superfamily
O3S71_RS07720	COG1937	Protein conserved in bacteria
O3S71_RS07725	COG2608	mercury ion transmembrane transporter activity
O3S71_RS07730	COG2217	Heavy metal translocating P-type atpase
O3S71_RS07745	COG2116	formate transmembrane transporter activity
O3S71_RS07750	COG1408	metallophosphoesterase
O3S71_RS07765	COG1113	amino acid transport
O3S71_RS07775	COG2322	membrane
O3S71_RS07780	COG1979	alcohol dehydrogenase
O3S71_RS07785	COG1349	DNA-binding transcription factor activity
O3S71_RS07790	COG1105	Belongs to the carbohydrate kinase PfkB family
O3S71_RS07795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O3S71_RS07795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O3S71_RS07795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O3S71_RS07800	COG1388	LysM domain
O3S71_RS07800	COG3584	3D domain protein
O3S71_RS07830	COG0464	growth
O3S71_RS07840	COG2860	membrane
O3S71_RS07845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
O3S71_RS07850	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
O3S71_RS07855	COG0789	Transcriptional regulator
O3S71_RS07860	COG0174	glutamine synthetase
O3S71_RS07865	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
O3S71_RS07900	COG0741	lytic transglycosylase activity
O3S71_RS07905	COG1196	nuclear chromosome segregation
O3S71_RS07905	COG0741	lytic transglycosylase activity
O3S71_RS07905	COG0739	heme binding
O3S71_RS07915	COG1695	Transcriptional regulator
O3S71_RS07935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
O3S71_RS07960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O3S71_RS07995	COG1132	(ABC) transporter
O3S71_RS08000	COG1132	(ABC) transporter
O3S71_RS08025	COG0730	response to heat
O3S71_RS08040	COG1346	cytolysis
O3S71_RS08050	COG0583	DNA-binding transcription factor activity
O3S71_RS08070	COG1131	(ABC) transporter
O3S71_RS08080	COG1473	amidohydrolase
O3S71_RS08090	COG0785	Cytochrome C biogenesis protein
O3S71_RS08095	COG4846	Membrane protein involved in cytochrome C biogenesis
O3S71_RS08145	COG0010	Belongs to the arginase family
O3S71_RS08150	COG1329	Transcriptional regulator
O3S71_RS08155	COG1902	pentaerythritol trinitrate reductase activity
O3S71_RS08160	COG0069	glutamate synthase activity
O3S71_RS08170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O3S71_RS08175	COG0346	lactoylglutathione lyase activity
O3S71_RS08180	COG0400	carboxylic ester hydrolase activity
O3S71_RS08185	COG5002	protein histidine kinase activity
O3S71_RS08195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O3S71_RS08230	COG1396	sequence-specific DNA binding
O3S71_RS08235	COG0318	PFAM AMP-dependent synthetase and ligase
O3S71_RS08240	COG1268	BioY protein
O3S71_RS08245	COG0318	PFAM AMP-dependent synthetase and ligase
O3S71_RS08250	COG0183	Belongs to the thiolase family
O3S71_RS08265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
O3S71_RS08275	COG2211	Major facilitator Superfamily
O3S71_RS08305	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
O3S71_RS08310	COG1132	(ABC) transporter
O3S71_RS08320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O3S71_RS08345	COG0824	Thioesterase
O3S71_RS08350	COG4841	protein insertion into membrane
O3S71_RS08370	COG0745	RESPONSE REGULATOR receiver
O3S71_RS08375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O3S71_RS08380	COG1832	CoA-binding protein
O3S71_RS08385	COG0187	DNA topoisomerase II activity
O3S71_RS08390	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
O3S71_RS08395	COG0673	inositol 2-dehydrogenase activity
O3S71_RS08415	COG1131	(ABC) transporter
O3S71_RS08425	COG1595	DNA-templated transcription, initiation
O3S71_RS08435	COG1316	TRANSCRIPTIONal
O3S71_RS08440	COG1301	dicarboxylic acid transport
O3S71_RS08445	COG4166	transmembrane transport
O3S71_RS08455	COG4166	transmembrane transport
O3S71_RS08460	COG2226	methyltransferase
O3S71_RS08495	COG0531	amino acid
O3S71_RS08510	COG0697	spore germination
O3S71_RS08515	COG3383	formate dehydrogenase (NAD+) activity
O3S71_RS08520	COG2427	Protein of unknown function (DUF1641)
O3S71_RS08525	COG5609	conserved protein (DUF2294)
O3S71_RS08530	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
O3S71_RS08540	COG2116	formate transmembrane transporter activity
O3S71_RS08545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
O3S71_RS08550	COG0303	'Molybdopterin
O3S71_RS08555	COG0314	molybdopterin synthase activity
O3S71_RS08565	COG0489	protein tyrosine kinase activity
O3S71_RS08580	COG3326	Membrane
O3S71_RS08585	COG2962	Rard protein
O3S71_RS08590	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
O3S71_RS08595	COG1657	PFAM Prenyltransferase squalene oxidase
O3S71_RS08605	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS08610	COG1012	belongs to the aldehyde dehydrogenase family
O3S71_RS08620	COG4145	pantothenate transmembrane transporter activity
O3S71_RS08635	COG0165	Argininosuccinate lyase
O3S71_RS08645	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS08665	COG0494	nUDIX hydrolase
O3S71_RS08675	COG0716	FMN binding
O3S71_RS08715	COG2720	vancomycin resistance protein
O3S71_RS08720	COG2514	catechol 2,3-dioxygenase activity
O3S71_RS08730	COG1285	pathogenesis
O3S71_RS08740	COG3852	Histidine kinase
O3S71_RS08765	COG1876	peptidase activity
O3S71_RS08780	COG1309	transcriptional regulator
O3S71_RS08785	COG0488	(ABC) transporter
O3S71_RS08835	COG0457	Tetratricopeptide repeat
O3S71_RS08855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
O3S71_RS08875	COG0697	spore germination
O3S71_RS08885	COG3397	chitin binding
O3S71_RS08890	COG0823	Involved in the tonB-independent uptake of proteins
O3S71_RS08900	COG0463	Glycosyl transferase, family 2
O3S71_RS08905	COG0463	Glycosyl transferase, family 2
O3S71_RS08910	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
O3S71_RS08920	COG1088	dTDP-glucose 4,6-dehydratase activity
O3S71_RS08925	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
O3S71_RS08930	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
O3S71_RS08945	COG2089	acid synthase
O3S71_RS08955	COG4641	Protein conserved in bacteria
O3S71_RS08970	COG1252	NADH dehydrogenase
O3S71_RS08990	COG0277	FAD linked oxidase domain protein
O3S71_RS08995	COG0385	Bile acid
O3S71_RS09005	COG0457	Tetratricopeptide repeat
O3S71_RS09020	COG0604	alcohol dehydrogenase
O3S71_RS09025	COG0640	Transcriptional regulator
O3S71_RS09040	COG0584	glycerophosphoryl diester phosphodiesterase
O3S71_RS09055	COG2271	Major facilitator Superfamily
O3S71_RS09065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O3S71_RS09070	COG1164	Oligoendopeptidase f
O3S71_RS09100	COG1193	negative regulation of DNA recombination
O3S71_RS09120	COG0583	DNA-binding transcription factor activity
O3S71_RS09155	COG3739	integral membrane protein
O3S71_RS09160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O3S71_RS09165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O3S71_RS09170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O3S71_RS09175	COG1247	-acetyltransferase
O3S71_RS09185	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
O3S71_RS09190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
O3S71_RS09220	COG2814	Major facilitator Superfamily
O3S71_RS09225	COG1113	amino acid transport
O3S71_RS09230	COG0604	alcohol dehydrogenase
O3S71_RS09235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O3S71_RS09265	COG2072	flavoprotein involved in K transport
O3S71_RS09300	COG1151	hydroxylamine reductase activity
O3S71_RS09345	COG1191	sigma factor activity
O3S71_RS09375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
O3S71_RS09385	COG1733	regulation of RNA biosynthetic process
O3S71_RS09390	COG2249	NAD(P)H dehydrogenase (quinone) activity
O3S71_RS09395	COG0318	PFAM AMP-dependent synthetase and ligase
O3S71_RS09430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O3S71_RS09460	COG0673	inositol 2-dehydrogenase activity
O3S71_RS09465	COG2188	Transcriptional regulator
O3S71_RS09470	COG1733	regulation of RNA biosynthetic process
O3S71_RS09505	COG0814	amino acid
O3S71_RS09525	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
O3S71_RS09530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
O3S71_RS09535	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
O3S71_RS09540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
O3S71_RS09545	COG1070	Carbohydrate kinase
O3S71_RS09550	COG2706	6-phosphogluconolactonase activity
O3S71_RS09555	COG3813	Protein conserved in bacteria
O3S71_RS09560	COG1357	PFAM Pentapeptide repeats (8 copies)
O3S71_RS09575	COG0697	spore germination
O3S71_RS09600	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
O3S71_RS09610	COG0789	Transcriptional regulator
O3S71_RS09615	COG1253	flavin adenine dinucleotide binding
O3S71_RS09645	COG0477	Major facilitator Superfamily
O3S71_RS09685	COG0628	permease
O3S71_RS09700	COG0110	maltose O-acetyltransferase activity
O3S71_RS09705	COG0738	Major facilitator superfamily
O3S71_RS09710	COG1940	carbohydrate kinase activity
O3S71_RS09715	COG0346	lactoylglutathione lyase activity
O3S71_RS09725	COG1051	belongs to the nudix hydrolase family
O3S71_RS09740	COG2365	Tyrosine phosphatase family
O3S71_RS09750	COG1011	Hydrolase
O3S71_RS09775	COG1131	(ABC) transporter
O3S71_RS09785	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS09815	COG0778	Nitroreductase
O3S71_RS09820	COG1733	regulation of RNA biosynthetic process
O3S71_RS09845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
O3S71_RS09850	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
O3S71_RS09860	COG2356	endonuclease I
O3S71_RS09865	COG1288	antiporter activity
O3S71_RS09920	COG2249	NAD(P)H dehydrogenase (quinone) activity
O3S71_RS09935	COG2031	fatty acid transporter
O3S71_RS09945	COG2814	Major facilitator Superfamily
O3S71_RS09950	COG1846	Transcriptional regulator
O3S71_RS09965	COG0477	Major facilitator Superfamily
O3S71_RS09975	COG2843	Capsule synthesis protein
O3S71_RS09980	COG1876	peptidase activity
O3S71_RS10025	COG5444	nuclease activity
O3S71_RS10040	COG5444	nuclease activity
O3S71_RS10105	COG2814	Major facilitator Superfamily
O3S71_RS10120	COG5632	N-Acetylmuramoyl-L-alanine amidase
O3S71_RS10120	COG3409	Peptidoglycan-binding domain 1 protein
O3S71_RS10140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O3S71_RS10140	COG2207	Transcriptional regulator
O3S71_RS10145	COG0662	Cupin 2, conserved barrel domain protein
O3S71_RS10165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
O3S71_RS10185	COG1619	proteins homologs of microcin C7 resistance protein MccF
O3S71_RS10200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O3S71_RS10210	COG3850	Histidine kinase
O3S71_RS10210	COG5002	protein histidine kinase activity
O3S71_RS10230	COG0577	efflux transmembrane transporter activity
O3S71_RS10255	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
O3S71_RS10280	COG2515	1-aminocyclopropane-1-carboxylate deaminase
O3S71_RS10290	COG2814	Major facilitator Superfamily
O3S71_RS10325	COG1136	(ABC) transporter
O3S71_RS10335	COG0277	FAD linked oxidase domain protein
O3S71_RS10375	COG3850	Histidine kinase
O3S71_RS10375	COG5002	protein histidine kinase activity
O3S71_RS10380	COG0745	RESPONSE REGULATOR receiver
O3S71_RS10405	COG0346	lactoylglutathione lyase activity
O3S71_RS10425	COG0640	Transcriptional regulator
O3S71_RS10430	COG0798	PFAM Bile acid sodium symporter
O3S71_RS10455	COG1121	(ABC) transporter
O3S71_RS10460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
O3S71_RS10465	COG0803	Belongs to the bacterial solute-binding protein 9 family
O3S71_RS10470	COG1575	Belongs to the MenA family. Type 1 subfamily
O3S71_RS10485	COG0697	spore germination
O3S71_RS10500	COG5609	conserved protein (DUF2294)
O3S71_RS10505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
O3S71_RS10515	COG0288	reversible hydration of carbon dioxide
O3S71_RS10520	COG0415	Belongs to the DNA photolyase family
O3S71_RS10545	COG1073	alpha beta
O3S71_RS10565	COG0598	Magnesium transport protein CorA
O3S71_RS10580	COG1476	TRANSCRIPTIONal
O3S71_RS10590	COG1846	Transcriptional regulator
O3S71_RS10595	COG0583	DNA-binding transcription factor activity
O3S71_RS10615	COG1335	isochorismatase
O3S71_RS10620	COG2267	carboxylic ester hydrolase activity
O3S71_RS10625	COG0737	Belongs to the 5'-nucleotidase family
O3S71_RS10640	COG2124	cytochrome p450
O3S71_RS10650	COG1115	amino acid carrier protein
O3S71_RS10660	COG4191	Histidine kinase
O3S71_RS10665	COG0784	Response regulator, receiver
O3S71_RS10670	COG0697	spore germination
O3S71_RS10675	COG0531	amino acid
O3S71_RS10685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
O3S71_RS10690	COG0531	amino acid
O3S71_RS10695	COG0322	excinuclease ABC activity
O3S71_RS10710	COG2207	Transcriptional regulator
O3S71_RS10740	COG5002	protein histidine kinase activity
O3S71_RS10765	COG1396	sequence-specific DNA binding
O3S71_RS10770	COG0252	asparaginase activity
O3S71_RS10775	COG1027	Aspartate ammonia-lyase
O3S71_RS10785	COG1063	alcohol dehydrogenase
O3S71_RS10815	COG1113	amino acid transport
O3S71_RS10820	COG1280	lysine exporter protein (LysE YggA)
O3S71_RS10825	COG3403	YqcI/YcgG family
O3S71_RS10830	COG5577	PFAM Coat F domain
O3S71_RS10850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O3S71_RS10855	COG3848	Pyruvate phosphate dikinase
O3S71_RS10855	COG0574	Belongs to the PEP-utilizing enzyme family
O3S71_RS10875	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
O3S71_RS10895	COG3314	Sporulation integral membrane protein YlbJ
O3S71_RS10910	COG1960	acyl-CoA dehydrogenase activity
O3S71_RS10920	COG0640	Transcriptional regulator
O3S71_RS10935	COG1414	Transcriptional regulator
O3S71_RS10940	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
O3S71_RS10945	COG1984	allophanate hydrolase subunit 2
O3S71_RS10975	COG0768	penicillin binding
O3S71_RS11000	COG5002	protein histidine kinase activity
O3S71_RS11010	COG1329	Transcriptional regulator
O3S71_RS11060	COG0833	amino acid
O3S71_RS11070	COG0730	response to heat
O3S71_RS11110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O3S71_RS11115	COG0697	spore germination
O3S71_RS11120	COG2816	NAD+ diphosphatase activity
O3S71_RS11130	COG0456	acetyltransferase
O3S71_RS11135	COG2207	Transcriptional regulator
O3S71_RS11155	COG3831	ATPase activity
O3S71_RS11155	COG4884	unkown
O3S71_RS11175	COG1846	Transcriptional regulator
O3S71_RS11180	COG0778	Nitroreductase
O3S71_RS11260	COG0753	catalase activity
O3S71_RS11265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
O3S71_RS11290	COG0714	Associated with various cellular activities
O3S71_RS11315	COG0346	lactoylglutathione lyase activity
O3S71_RS11340	COG3655	Transcriptional regulator
O3S71_RS11350	COG1785	Belongs to the alkaline phosphatase family
O3S71_RS11355	COG2720	vancomycin resistance protein
O3S71_RS11365	COG3239	Fatty acid desaturase
O3S71_RS11380	COG0833	amino acid
O3S71_RS11385	COG1414	Transcriptional regulator
O3S71_RS11390	COG4187	Peptidase family M20/M25/M40
O3S71_RS11395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
O3S71_RS11410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O3S71_RS11425	COG2329	Antibiotic biosynthesis monooxygenase
O3S71_RS11455	COG1070	Carbohydrate kinase
O3S71_RS11460	COG2390	Transcriptional regulator
O3S71_RS11465	COG1129	ABC transporter
O3S71_RS11470	COG1172	Belongs to the binding-protein-dependent transport system permease family
O3S71_RS11480	COG1879	ABC-type sugar transport system periplasmic component
O3S71_RS11510	COG3584	3D domain protein
O3S71_RS11510	COG1388	LysM domain
O3S71_RS11550	COG1605	Chorismate mutase
O3S71_RS11550	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
O3S71_RS11565	COG0287	Prephenate dehydrogenase
O3S71_RS11580	COG1309	transcriptional regulator
O3S71_RS11585	COG1033	growth of symbiont in host cell
O3S71_RS11585	COG2409	Drug exporters of the RND superfamily
O3S71_RS11590	COG0488	(ABC) transporter
O3S71_RS11595	COG1368	sulfuric ester hydrolase activity
O3S71_RS11600	COG0861	Integral membrane protein TerC family
O3S71_RS11630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O3S71_RS11635	COG0346	lactoylglutathione lyase activity
O3S71_RS11640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
O3S71_RS11645	COG4912	Dna alkylation repair
O3S71_RS11665	COG2318	DinB family
O3S71_RS11670	COG0697	spore germination
O3S71_RS11680	COG2746	aminoglycoside 3-N-acetyltransferase activity
O3S71_RS11710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
O3S71_RS11715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
O3S71_RS11735	COG0628	permease
O3S71_RS11780	COG1131	(ABC) transporter
O3S71_RS11795	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
O3S71_RS11805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
O3S71_RS11810	COG0436	Aminotransferase
O3S71_RS11860	COG2261	transglycosylase associated protein
O3S71_RS11885	COG0477	Major facilitator Superfamily
O3S71_RS11885	COG2814	Major facilitator Superfamily
O3S71_RS11890	COG4533	DNA binding
O3S71_RS11895	COG0789	Transcriptional regulator
O3S71_RS11900	COG1664	Polymer-forming cytoskeletal
O3S71_RS11910	COG2814	Major facilitator Superfamily
O3S71_RS11950	COG1307	EDD domain protein, DegV family
O3S71_RS11955	COG1164	Oligoendopeptidase f
O3S71_RS11980	COG0745	RESPONSE REGULATOR receiver
O3S71_RS11985	COG3850	Histidine kinase
O3S71_RS11985	COG5002	protein histidine kinase activity
O3S71_RS12030	COG0667	Aldo Keto reductase
O3S71_RS12045	COG4948	Mandelate Racemase Muconate Lactonizing
O3S71_RS12055	COG4166	transmembrane transport
O3S71_RS12060	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
O3S71_RS12070	COG0586	Pfam SNARE associated Golgi protein
O3S71_RS12110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
O3S71_RS12115	COG3938	Belongs to the proline racemase family
O3S71_RS12125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
O3S71_RS12130	COG1012	belongs to the aldehyde dehydrogenase family
O3S71_RS12135	COG1115	amino acid carrier protein
O3S71_RS12140	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
O3S71_RS12155	COG3397	chitin binding
O3S71_RS12170	COG4637	Psort location Cytoplasmic, score
O3S71_RS12215	COG0514	ATP-dependent DNA helicase (RecQ)
O3S71_RS12220	COG2105	PFAM AIG2 family protein
O3S71_RS12230	COG3973	AAA domain
O3S71_RS12235	COG0456	acetyltransferase
O3S71_RS12285	COG2315	Protein conserved in bacteria
O3S71_RS12290	COG2226	methyltransferase
O3S71_RS12295	COG2205	protein histidine kinase activity
O3S71_RS12305	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
O3S71_RS12320	COG3397	chitin binding
O3S71_RS12340	COG2153	protein acetylation
O3S71_RS12370	COG0517	IMP dehydrogenase activity
O3S71_RS12370	COG4175	Glycine betaine
O3S71_RS12375	COG4176	ABC-type proline glycine betaine transport system permease component
O3S71_RS12405	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS12415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
O3S71_RS12420	COG0022	dehydrogenase e1 component
O3S71_RS12425	COG0508	dehydrogenase complex catalyzes the overall conversion of
O3S71_RS12430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
O3S71_RS12445	COG1959	2 iron, 2 sulfur cluster binding
O3S71_RS12460	COG1349	DNA-binding transcription factor activity
O3S71_RS12475	COG3284	Transcriptional regulator
O3S71_RS12495	COG1309	transcriptional regulator
O3S71_RS12535	COG2959	enzyme of heme biosynthesis
O3S71_RS12550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O3S71_RS12585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O3S71_RS12590	COG0697	spore germination
O3S71_RS12595	COG0201	protein transport
O3S71_RS12615	COG0737	Belongs to the 5'-nucleotidase family
O3S71_RS12620	COG3227	Zinc metalloprotease (Elastase)
O3S71_RS12625	COG1523	belongs to the glycosyl hydrolase 13 family
O3S71_RS12640	COG0076	glutamate decarboxylase activity
O3S71_RS12645	COG0657	acetylesterase activity
O3S71_RS12650	COG1073	alpha beta
O3S71_RS12655	COG0577	efflux transmembrane transporter activity
O3S71_RS12660	COG1136	(ABC) transporter
O3S71_RS12675	COG5002	protein histidine kinase activity
O3S71_RS12680	COG0745	RESPONSE REGULATOR receiver
O3S71_RS12685	COG1011	Hydrolase
O3S71_RS12710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
O3S71_RS12730	COG1132	(ABC) transporter
O3S71_RS12735	COG1131	(ABC) transporter
O3S71_RS12755	COG1819	glycosyl
O3S71_RS12760	COG1819	glycosyl
O3S71_RS12795	COG0322	excinuclease ABC activity
O3S71_RS12835	COG4667	esterase of the alpha-beta hydrolase superfamily
O3S71_RS12860	COG3878	Protein conserved in bacteria
O3S71_RS12885	COG1051	belongs to the nudix hydrolase family
O3S71_RS12890	COG0592	DNA-directed DNA polymerase activity
O3S71_RS12905	COG2223	nitrite transmembrane transporter activity
O3S71_RS12915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O3S71_RS12925	COG0494	nUDIX hydrolase
O3S71_RS12950	COG0697	spore germination
O3S71_RS12955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O3S71_RS12980	COG0584	glycerophosphoryl diester phosphodiesterase
O3S71_RS13040	COG0768	penicillin binding
O3S71_RS13045	COG0671	phosphoesterase, PA-phosphatase related
O3S71_RS13050	COG0604	alcohol dehydrogenase
O3S71_RS13055	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
O3S71_RS13080	COG2169	Transcriptional regulator
O3S71_RS13140	COG2205	protein histidine kinase activity
O3S71_RS13165	COG1794	racemase activity, acting on amino acids and derivatives
O3S71_RS13170	COG1819	glycosyl
O3S71_RS13180	COG0768	penicillin binding
O3S71_RS13185	COG5002	protein histidine kinase activity
O3S71_RS13190	COG0561	phosphatase activity
O3S71_RS13225	COG2124	cytochrome p450
O3S71_RS13270	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
O3S71_RS13275	COG5632	N-Acetylmuramoyl-L-alanine amidase
O3S71_RS13350	COG0740	serine-type endopeptidase activity
O3S71_RS13395	COG0582	viral genome integration into host DNA
O3S71_RS13460	COG1484	DNA-dependent DNA replication
O3S71_RS13490	COG1396	sequence-specific DNA binding
O3S71_RS13510	COG0582	viral genome integration into host DNA
O3S71_RS13540	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
O3S71_RS13550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O3S71_RS13575	COG0577	efflux transmembrane transporter activity
O3S71_RS13580	COG1136	(ABC) transporter
O3S71_RS13595	COG0488	(ABC) transporter
O3S71_RS13600	COG0667	Aldo Keto reductase
O3S71_RS13605	COG0583	DNA-binding transcription factor activity
O3S71_RS13610	COG2205	protein histidine kinase activity
O3S71_RS13615	COG0745	RESPONSE REGULATOR receiver
O3S71_RS13625	COG3773	Cell wall hydrolase
O3S71_RS13630	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
O3S71_RS13640	COG3386	PFAM SMP-30 Gluconolaconase
O3S71_RS13650	COG0693	protein deglycase activity
O3S71_RS13660	COG2323	membrane
O3S71_RS13670	COG1063	alcohol dehydrogenase
O3S71_RS13690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O3S71_RS13730	COG1733	regulation of RNA biosynthetic process
O3S71_RS13735	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS13745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
O3S71_RS13775	COG2207	Transcriptional regulator
O3S71_RS13780	COG3227	Zinc metalloprotease (Elastase)
O3S71_RS13795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
O3S71_RS13825	COG1686	Belongs to the peptidase S11 family
O3S71_RS13845	COG0572	uridine kinase
O3S71_RS13865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
O3S71_RS13870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
O3S71_RS13875	COG1024	Enoyl-CoA hydratase
O3S71_RS13880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
O3S71_RS13885	COG0511	ligase activity, forming carbon-carbon bonds
O3S71_RS13890	COG0439	Biotin carboxylase
O3S71_RS13895	COG1960	acyl-CoA dehydrogenase activity
O3S71_RS13910	COG1309	transcriptional regulator
O3S71_RS13920	COG1131	(ABC) transporter
O3S71_RS13930	COG1408	metallophosphoesterase
O3S71_RS13940	COG0768	penicillin binding
O3S71_RS13945	COG0768	penicillin binding
O3S71_RS13955	COG1595	DNA-templated transcription, initiation
O3S71_RS13960	COG0768	penicillin binding
O3S71_RS14020	COG1404	Belongs to the peptidase S8 family
O3S71_RS14030	COG4585	Histidine kinase
O3S71_RS14035	COG0367	asparagine synthase
O3S71_RS14040	COG1309	transcriptional regulator
O3S71_RS14060	COG1396	sequence-specific DNA binding
O3S71_RS14105	COG2814	Major facilitator Superfamily
O3S71_RS14110	COG2234	aminopeptidase activity
O3S71_RS14120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
O3S71_RS14135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
O3S71_RS14140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O3S71_RS14145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
O3S71_RS14160	COG0456	acetyltransferase
O3S71_RS14170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O3S71_RS14180	COG0741	lytic transglycosylase activity
O3S71_RS14230	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS14260	COG2814	Major facilitator Superfamily
O3S71_RS14275	COG1686	Belongs to the peptidase S11 family
O3S71_RS14285	COG0730	response to heat
O3S71_RS14295	COG2002	toxin-antitoxin pair type II binding
O3S71_RS14320	COG2195	Cleaves the N-terminal amino acid of tripeptides
O3S71_RS14355	COG3961	Belongs to the TPP enzyme family
O3S71_RS14360	COG2226	methyltransferase
O3S71_RS14370	COG0500	methyltransferase
O3S71_RS14370	COG3615	Tellurite resistance protein tehB
O3S71_RS14490	COG1309	transcriptional regulator
O3S71_RS14510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O3S71_RS14525	COG1846	Transcriptional regulator
O3S71_RS14535	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
O3S71_RS14545	COG2971	BadF BadG BcrA BcrD
O3S71_RS14570	COG1649	PFAM Uncharacterised BCR, COG1649
O3S71_RS14600	COG1595	DNA-templated transcription, initiation
O3S71_RS14605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
O3S71_RS14635	COG1396	sequence-specific DNA binding
O3S71_RS14660	COG1132	(ABC) transporter
O3S71_RS14665	COG1132	(ABC) transporter
O3S71_RS14680	COG2258	MOSC domain
O3S71_RS14685	COG0583	DNA-binding transcription factor activity
O3S71_RS14700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
O3S71_RS14705	COG0583	DNA-binding transcription factor activity
O3S71_RS14745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O3S71_RS14755	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
O3S71_RS14780	COG1247	-acetyltransferase
O3S71_RS14815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O3S71_RS14830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
O3S71_RS14875	COG1136	(ABC) transporter
O3S71_RS14880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
O3S71_RS14885	COG1187	pseudouridine synthase activity
O3S71_RS14905	COG1115	amino acid carrier protein
O3S71_RS14915	COG2318	DinB family
O3S71_RS14925	COG0776	regulation of translation
O3S71_RS14940	COG2814	Major facilitator Superfamily
O3S71_RS14945	COG3251	PFAM MbtH domain protein
O3S71_RS14950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O3S71_RS14955	COG1535	isochorismatase
O3S71_RS14955	COG3433	isochorismatase activity
O3S71_RS14960	COG1021	2,3-dihydroxybenzoate-AMP ligase
O3S71_RS14965	COG1169	isochorismate synthase
O3S71_RS14970	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS14975	COG2223	nitrite transmembrane transporter activity
O3S71_RS14995	COG0419	ATPase involved in DNA repair
O3S71_RS15000	COG0420	3'-5' exonuclease activity
O3S71_RS15015	COG1024	Enoyl-CoA hydratase
O3S71_RS15020	COG1280	lysine exporter protein (LysE YggA)
O3S71_RS15030	COG2084	Dehydrogenase
O3S71_RS15035	COG1960	acyl-CoA dehydrogenase activity
O3S71_RS15045	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
O3S71_RS15050	COG2079	MmgE PrpD family protein
O3S71_RS15055	COG0372	Belongs to the citrate synthase family
O3S71_RS15060	COG4841	protein insertion into membrane
O3S71_RS15065	COG2814	Major facilitator Superfamily
O3S71_RS15075	COG4499	WXG100 protein secretion system (Wss), protein YukC
O3S71_RS15075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O3S71_RS15095	COG0300	oxidoreductase activity
O3S71_RS15195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O3S71_RS15200	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
O3S71_RS15205	COG0671	phosphoesterase, PA-phosphatase related
O3S71_RS15215	COG4991	sh3 domain protein
O3S71_RS15215	COG0515	serine threonine protein kinase
O3S71_RS15215	COG3064	Membrane
O3S71_RS15250	COG1509	lysine 2,3-aminomutase activity
O3S71_RS15255	COG3829	transcription factor binding
O3S71_RS15260	COG0456	acetyltransferase
O3S71_RS15265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O3S71_RS15270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
O3S71_RS15275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
O3S71_RS15280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
O3S71_RS15295	COG5506	Protein of unknown function (DUF1694)
O3S71_RS15300	COG1012	belongs to the aldehyde dehydrogenase family
O3S71_RS15305	COG1253	flavin adenine dinucleotide binding
O3S71_RS15340	COG1174	glycine betaine transport
O3S71_RS15345	COG0517	IMP dehydrogenase activity
O3S71_RS15345	COG1125	glycine betaine transport
O3S71_RS15380	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
O3S71_RS15390	COG1070	Carbohydrate kinase
O3S71_RS15405	COG1064	alcohol dehydrogenase
O3S71_RS15410	COG0384	phenazine biosynthesis protein PhzF
O3S71_RS15415	COG1737	Transcriptional regulator
O3S71_RS15420	COG2197	response regulator
O3S71_RS15425	COG2203	Gaf domain
O3S71_RS15425	COG4585	Histidine kinase
O3S71_RS15430	COG0668	transmembrane transport
O3S71_RS15435	COG1051	belongs to the nudix hydrolase family
O3S71_RS15440	COG1335	isochorismatase
O3S71_RS15460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O3S71_RS15465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O3S71_RS15470	COG0860	N-Acetylmuramoyl-L-alanine amidase
O3S71_RS15485	COG0367	asparagine synthase
O3S71_RS15490	COG0071	Belongs to the small heat shock protein (HSP20) family
O3S71_RS15495	COG1999	signal sequence binding
O3S71_RS15505	COG1307	EDD domain protein, DegV family
O3S71_RS15515	COG0805	protein transport
O3S71_RS15525	COG1272	protein, Hemolysin III
O3S71_RS15530	COG0204	Acyl-transferase
O3S71_RS15540	COG0768	penicillin binding
O3S71_RS15555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O3S71_RS15570	COG0546	phosphoglycolate phosphatase activity
O3S71_RS15585	COG1131	(ABC) transporter
O3S71_RS15595	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
O3S71_RS15600	COG3655	Transcriptional regulator
O3S71_RS15610	COG0456	acetyltransferase
O3S71_RS15620	COG1794	racemase activity, acting on amino acids and derivatives
O3S71_RS15630	COG2610	gluconate transmembrane transporter activity
O3S71_RS15655	COG0733	neurotransmitter:sodium symporter activity
O3S71_RS15660	COG0017	Asparaginyl-tRNA synthetase
O3S71_RS15690	COG0018	arginyl-trna synthetase
O3S71_RS15695	COG2136	Putative SAM-dependent methyltransferase
O3S71_RS15695	COG2521	methyltransferase
O3S71_RS15710	COG1413	lyase activity
O3S71_RS15725	COG0629	single-stranded DNA binding
O3S71_RS15740	COG0488	(ABC) transporter
O3S71_RS15745	COG1418	mRNA catabolic process
O3S71_RS15760	COG0457	Tetratricopeptide repeat
O3S71_RS15775	COG2359	stage V sporulation protein S
O3S71_RS15810	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
O3S71_RS15815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
O3S71_RS15820	COG2146	nitrite reductase [NAD(P)H] activity
O3S71_RS15825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
O3S71_RS15825	COG1587	Uroporphyrinogen-III synthase
O3S71_RS15830	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
O3S71_RS15835	COG1648	precorrin-2 dehydrogenase activity
O3S71_RS15850	COG2223	nitrite transmembrane transporter activity
O3S71_RS15860	COG0314	molybdopterin synthase activity
O3S71_RS15865	COG0303	'Molybdopterin
O3S71_RS15870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
O3S71_RS15875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
O3S71_RS15880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
O3S71_RS15885	COG2181	nitrate reductase activity
O3S71_RS15890	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
O3S71_RS15895	COG1140	nitrate reductase beta subunit
O3S71_RS15900	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
O3S71_RS15905	COG0714	Associated with various cellular activities
O3S71_RS15910	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
O3S71_RS15915	COG1305	Transglutaminase-like
O3S71_RS15920	COG0386	Belongs to the glutathione peroxidase family
O3S71_RS15935	COG0426	domain, Protein
O3S71_RS15935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
O3S71_RS15945	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
O3S71_RS15955	COG1595	DNA-templated transcription, initiation
O3S71_RS15960	COG0604	alcohol dehydrogenase
O3S71_RS15970	COG0346	lactoylglutathione lyase activity
O3S71_RS15975	COG1082	Xylose isomerase domain protein TIM barrel
O3S71_RS15995	COG2226	methyltransferase
O3S71_RS16020	COG3874	Sporulation protein YtfJ
O3S71_RS16120	COG0456	acetyltransferase
O3S71_RS16150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O3S71_RS16155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O3S71_RS16160	COG1819	glycosyl
O3S71_RS16175	COG4106	trans-aconitate 2-methyltransferase activity
O3S71_RS16180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
O3S71_RS16190	COG2814	Major facilitator Superfamily
O3S71_RS16195	COG1846	Transcriptional regulator
O3S71_RS16210	COG0860	N-Acetylmuramoyl-L-alanine amidase
O3S71_RS16225	COG2211	Major facilitator Superfamily
O3S71_RS16240	COG1876	peptidase activity
O3S71_RS16250	COG0860	N-Acetylmuramoyl-L-alanine amidase
O3S71_RS16270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O3S71_RS16275	COG1114	Component of the transport system for branched-chain amino acids
O3S71_RS16300	COG1253	flavin adenine dinucleotide binding
O3S71_RS16305	COG2839	Protein conserved in bacteria
O3S71_RS16310	COG0702	epimerase
O3S71_RS16325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O3S71_RS16335	COG1607	acyl-coa hydrolase
O3S71_RS16340	COG3689	TIGRFAM TIGR03943 family protein
O3S71_RS16345	COG0701	Predicted permease
O3S71_RS16355	COG2244	polysaccharide biosynthetic process
O3S71_RS16360	COG0586	Pfam SNARE associated Golgi protein
O3S71_RS16365	COG1051	belongs to the nudix hydrolase family
O3S71_RS16370	COG5337	Spore coat protein CotH
O3S71_RS16380	COG0406	alpha-ribazole phosphatase activity
O3S71_RS16395	COG4166	transmembrane transport
O3S71_RS16405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
O3S71_RS16415	COG0702	epimerase
O3S71_RS16425	COG0803	Belongs to the bacterial solute-binding protein 9 family
O3S71_RS16430	COG0456	acetyltransferase
O3S71_RS16435	COG0523	cobalamin synthesis protein
O3S71_RS16440	COG4989	oxidoreductase activity
O3S71_RS16445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O3S71_RS16450	COG1231	oxidoreductase activity
O3S71_RS16460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O3S71_RS16475	COG0783	Belongs to the Dps family
O3S71_RS16480	COG3949	Membrane
O3S71_RS16495	COG0840	transmembrane signaling receptor activity
O3S71_RS16530	COG0667	Aldo Keto reductase
O3S71_RS16535	COG0640	Transcriptional regulator
O3S71_RS16540	COG1404	Belongs to the peptidase S8 family
O3S71_RS16545	COG2002	toxin-antitoxin pair type II binding
O3S71_RS16550	COG0577	efflux transmembrane transporter activity
O3S71_RS16585	COG1752	Esterase of the alpha-beta hydrolase superfamily
O3S71_RS16595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O3S71_RS16600	COG1279	arginine transmembrane transporter activity
O3S71_RS16605	COG2814	Major facilitator Superfamily
O3S71_RS16615	COG1082	Xylose isomerase domain protein TIM barrel
O3S71_RS16625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O3S71_RS16645	COG1247	-acetyltransferase
O3S71_RS16650	COG1285	pathogenesis
O3S71_RS16665	COG1316	TRANSCRIPTIONal
O3S71_RS16690	COG0460	homoserine dehydrogenase
O3S71_RS16730	COG0300	oxidoreductase activity
O3S71_RS16735	COG5002	protein histidine kinase activity
O3S71_RS16740	COG0745	RESPONSE REGULATOR receiver
O3S71_RS16905	COG0305	Participates in initiation and elongation during chromosome replication
O3S71_RS16935	COG3646	Phage regulatory protein
O3S71_RS17005	COG1132	(ABC) transporter
O3S71_RS17015	COG1388	LysM domain
O3S71_RS17015	COG0791	NLP P60 protein
O3S71_RS17030	COG1686	Belongs to the peptidase S11 family
O3S71_RS17070	COG1216	Glycosyl transferase, family 2
O3S71_RS17080	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
O3S71_RS17085	COG4988	ABC transporter
O3S71_RS17090	COG1294	oxidase, subunit
O3S71_RS17095	COG1271	oxidase subunit
O3S71_RS17115	COG1942	4-Oxalocrotonate Tautomerase
O3S71_RS17125	COG0583	DNA-binding transcription factor activity
O3S71_RS17145	COG0411	ABC transporter
O3S71_RS17155	COG0523	cobalamin synthesis protein
O3S71_RS17160	COG1231	oxidoreductase activity
O3S71_RS17170	COG0628	permease
O3S71_RS17185	COG0778	Nitroreductase
O3S71_RS17190	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
O3S71_RS17195	COG1959	2 iron, 2 sulfur cluster binding
O3S71_RS17200	COG0583	DNA-binding transcription factor activity
O3S71_RS17205	COG0697	spore germination
O3S71_RS17210	COG4549	nuclear export factor GLE1
O3S71_RS17215	COG1276	copper resistance
O3S71_RS17215	COG2372	response to copper ion
O3S71_RS17225	COG1114	Component of the transport system for branched-chain amino acids
O3S71_RS17250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
O3S71_RS17260	COG2132	Multicopper oxidase
O3S71_RS17270	COG0006	proline dipeptidase activity
O3S71_RS17280	COG4846	Membrane protein involved in cytochrome C biogenesis
O3S71_RS17320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
O3S71_RS17325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O3S71_RS17335	COG2390	Transcriptional regulator
O3S71_RS17340	COG1309	transcriptional regulator
O3S71_RS17355	COG0456	acetyltransferase
O3S71_RS17370	COG2309	aminopeptidase activity
O3S71_RS17395	COG0531	amino acid
O3S71_RS17405	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
O3S71_RS17420	COG1914	H( )-stimulated, divalent metal cation uptake system
O3S71_RS17425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O3S71_RS17430	COG4166	transmembrane transport
O3S71_RS17450	COG0427	acetyl-CoA hydrolase
O3S71_RS17455	COG3279	Response regulator of the LytR AlgR family
O3S71_RS17470	COG3384	dioxygenase
O3S71_RS17475	COG2814	Major facilitator Superfamily
O3S71_RS17500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
O3S71_RS17520	COG0028	Belongs to the TPP enzyme family
O3S71_RS17525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O3S71_RS17535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
O3S71_RS17555	COG2323	membrane
O3S71_RS17560	COG5566	PFAM Mor transcription activator
O3S71_RS17570	COG0733	neurotransmitter:sodium symporter activity
O3S71_RS17590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
O3S71_RS17595	COG2223	nitrite transmembrane transporter activity
O3S71_RS17600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
O3S71_RS17610	COG0477	Major facilitator Superfamily
O3S71_RS17620	COG1695	Transcriptional regulator
O3S71_RS17635	COG2814	Major facilitator Superfamily
O3S71_RS17680	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
O3S71_RS17685	COG0784	Response regulator, receiver
O3S71_RS17690	COG4191	Histidine kinase
O3S71_RS17695	COG0281	malic enzyme
O3S71_RS17700	COG1027	Aspartate ammonia-lyase
O3S71_RS17710	COG0528	UMP kinase activity
O3S71_RS17715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O3S71_RS17730	COG1131	(ABC) transporter
O3S71_RS17765	COG2733	membrane
O3S71_RS17805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O3S71_RS17810	COG0785	Cytochrome C biogenesis protein
O3S71_RS17830	COG3340	Belongs to the peptidase S51 family
O3S71_RS17835	COG0534	Mate efflux family protein
O3S71_RS17870	COG0789	Transcriptional regulator
O3S71_RS17875	COG1757	Na H antiporter
O3S71_RS17880	COG0438	transferase activity, transferring glycosyl groups
O3S71_RS17880	COG1216	Glycosyl transferase, family 2
O3S71_RS17890	COG0701	Predicted permease
O3S71_RS17895	COG0523	cobalamin synthesis protein
O3S71_RS17930	COG0367	asparagine synthase
O3S71_RS17940	COG1846	Transcriptional regulator
O3S71_RS17960	COG0406	alpha-ribazole phosphatase activity
O3S71_RS18015	COG3842	ATPase activity
O3S71_RS18020	COG0583	DNA-binding transcription factor activity
O3S71_RS18045	COG1215	transferase activity, transferring glycosyl groups
O3S71_RS18050	COG2329	Antibiotic biosynthesis monooxygenase
O3S71_RS18080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
O3S71_RS18085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O3S71_RS18090	COG4786	Flagellar basal body rod
O3S71_RS18095	COG1419	protein localization to endoplasmic reticulum
O3S71_RS18100	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
O3S71_RS18105	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
O3S71_RS18115	COG1987	bacterial-type flagellum assembly
O3S71_RS18120	COG1338	Plays a role in the flagellum-specific transport system
O3S71_RS18130	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
O3S71_RS18130	COG1776	CheC inhibitor of MCP methylation
O3S71_RS18135	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
O3S71_RS18145	COG0741	lytic transglycosylase activity
O3S71_RS18150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
O3S71_RS18155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
O3S71_RS18165	COG0835	chemotaxis
O3S71_RS18165	COG0784	Response regulator, receiver
O3S71_RS18180	COG1749	Flagellar hook protein flgE
O3S71_RS18200	COG1157	protein secretion by the type III secretion system
O3S71_RS18210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
O3S71_RS18215	COG1766	The M ring may be actively involved in energy transduction
O3S71_RS18225	COG1558	bacterial-type flagellum-dependent cell motility
O3S71_RS18230	COG1815	bacterial-type flagellum-dependent cell motility
O3S71_RS18245	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
O3S71_RS18250	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
O3S71_RS18255	COG1256	bacterial-type flagellum assembly
O3S71_RS18275	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
O3S71_RS18290	COG1776	CheC inhibitor of MCP methylation
O3S71_RS18290	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
O3S71_RS18295	COG2198	Histidine kinase
O3S71_RS18295	COG0643	Histidine kinase
O3S71_RS18300	COG2201	protein-glutamate methylesterase activity
O3S71_RS18305	COG1360	Flagellar Motor Protein
O3S71_RS18310	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
O3S71_RS18320	COG1923	regulation of RNA biosynthetic process
O3S71_RS18360	COG1434	Gram-negative-bacterium-type cell wall biogenesis
O3S71_RS18365	COG2323	membrane
O3S71_RS18375	COG0789	Transcriptional regulator
O3S71_RS18375	COG4978	Transcriptional regulator
O3S71_RS18380	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
O3S71_RS18385	COG0475	glutathione-regulated potassium exporter activity
O3S71_RS18395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
O3S71_RS18400	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O3S71_RS18420	COG1280	lysine exporter protein (LysE YggA)
O3S71_RS18425	COG3403	YqcI/YcgG family
O3S71_RS18460	COG0328	RNA-DNA hybrid ribonuclease activity
O3S71_RS18480	COG0454	-acetyltransferase
O3S71_RS18495	COG0438	transferase activity, transferring glycosyl groups
O3S71_RS18500	COG1215	transferase activity, transferring glycosyl groups
O3S71_RS18515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
O3S71_RS18540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
O3S71_RS18555	COG0754	glutathionylspermidine amidase activity
O3S71_RS18590	COG0456	acetyltransferase
O3S71_RS18600	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
O3S71_RS18625	COG2233	PERMEase
O3S71_RS18635	COG0024	Methionine aminopeptidase
O3S71_RS18655	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
O3S71_RS18660	COG1199	ATP-dependent helicase activity
O3S71_RS18670	COG0116	Belongs to the methyltransferase superfamily
O3S71_RS18725	COG4499	WXG100 protein secretion system (Wss), protein YukC
O3S71_RS18725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O3S71_RS18735	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
O3S71_RS18740	COG3935	DnaD domain protein
O3S71_RS18760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
O3S71_RS18760	COG1199	ATP-dependent helicase activity
O3S71_RS18795	COG0438	transferase activity, transferring glycosyl groups
O3S71_RS18815	COG1694	Mazg nucleotide pyrophosphohydrolase
O3S71_RS18820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O3S71_RS18830	COG2738	Putative neutral zinc metallopeptidase
O3S71_RS18845	COG4347	Protein of unknown function (DUF1405)
O3S71_RS18850	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
O3S71_RS18850	COG2010	Cytochrome c
O3S71_RS18855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
O3S71_RS18875	COG0457	Tetratricopeptide repeat
O3S71_RS18920	COG0142	geranyltranstransferase activity
O3S71_RS18930	COG0142	geranyltranstransferase activity
O3S71_RS18945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
O3S71_RS19015	COG0252	asparaginase activity
O3S71_RS19020	COG0492	ferredoxin-NADP+ reductase activity
O3S71_RS19040	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
O3S71_RS19050	COG0789	Transcriptional regulator
O3S71_RS19055	COG1408	metallophosphoesterase
O3S71_RS19065	COG1266	CAAX protease self-immunity
O3S71_RS19070	COG0514	ATP-dependent DNA helicase (RecQ)
O3S71_RS19080	COG1141	Ferredoxin
O3S71_RS19085	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
O3S71_RS19100	COG2096	Adenosyltransferase
O3S71_RS19105	COG5002	protein histidine kinase activity
O3S71_RS19110	COG0745	RESPONSE REGULATOR receiver
O3S71_RS19115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
O3S71_RS19120	COG1333	cytochrome c biogenesis protein
O3S71_RS19130	COG1187	pseudouridine synthase activity
O3S71_RS19135	COG0700	Nucleoside recognition
O3S71_RS19140	COG2715	membrane protein required for spore maturation
O3S71_RS19145	COG1686	Belongs to the peptidase S11 family
O3S71_RS19150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
O3S71_RS19165	COG0392	lysyltransferase activity
O3S71_RS19165	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
O3S71_RS19180	COG5002	protein histidine kinase activity
O3S71_RS19185	COG0582	viral genome integration into host DNA
O3S71_RS19195	COG1801	Protein of unknown function DUF72
O3S71_RS19200	COG3852	Histidine kinase
O3S71_RS19215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O3S71_RS19220	COG1392	Phosphate transport regulator
O3S71_RS19225	COG0306	phosphate transporter
O3S71_RS19230	COG0730	response to heat
O3S71_RS19280	COG1114	Component of the transport system for branched-chain amino acids
O3S71_RS19290	COG2197	response regulator
O3S71_RS19295	COG4585	Histidine kinase
O3S71_RS19300	COG4758	membrane
O3S71_RS19315	COG1757	Na H antiporter
O3S71_RS19340	COG0733	neurotransmitter:sodium symporter activity
O3S71_RS19345	COG1648	precorrin-2 dehydrogenase activity
O3S71_RS19365	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
O3S71_RS19370	COG0529	Catalyzes the synthesis of activated sulfate
O3S71_RS19390	COG0019	diaminopimelate decarboxylase activity
O3S71_RS19400	COG1368	sulfuric ester hydrolase activity
O3S71_RS19405	COG1183	phosphatidylcholine synthase activity
O3S71_RS19420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
O3S71_RS19495	COG0440	acetolactate synthase activity
O3S71_RS19500	COG0028	Belongs to the TPP enzyme family
O3S71_RS19505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O3S71_RS19525	COG3874	Sporulation protein YtfJ
O3S71_RS19530	COG4709	membrane
O3S71_RS19535	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
O3S71_RS19550	COG1301	dicarboxylic acid transport
O3S71_RS19560	COG1846	Transcriptional regulator
O3S71_RS19615	COG0716	FMN binding
O3S71_RS19640	COG1696	Membrane protein involved in D-alanine export
O3S71_RS19650	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
O3S71_RS19655	COG2070	2-Nitropropane dioxygenase
O3S71_RS19660	COG1619	proteins homologs of microcin C7 resistance protein MccF
O3S71_RS19670	COG1335	isochorismatase
O3S71_RS19680	COG1522	sequence-specific DNA binding
O3S71_RS19700	COG1131	(ABC) transporter
O3S71_RS19710	COG1131	(ABC) transporter
O3S71_RS19715	COG1725	Transcriptional regulator
O3S71_RS19730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
O3S71_RS19735	COG1780	Probably involved in ribonucleotide reductase function
O3S71_RS19765	COG4873	Protein conserved in bacteria
O3S71_RS19780	COG0720	synthase
O3S71_RS19790	COG5002	protein histidine kinase activity
O3S71_RS19800	COG2318	DinB family
O3S71_RS19810	COG1846	Transcriptional regulator
O3S71_RS19815	COG3852	Histidine kinase
O3S71_RS19825	COG2861	carbohydrate metabolic process
O3S71_RS19835	COG0235	Class ii aldolase
O3S71_RS19845	COG1349	DNA-binding transcription factor activity
O3S71_RS19870	COG3842	ATPase activity
O3S71_RS19875	COG1840	ABC-type Fe3 transport system, periplasmic component
O3S71_RS19890	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
O3S71_RS19900	COG3243	poly(R)-hydroxyalkanoic acid synthase
O3S71_RS19905	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS19925	COG2030	dehydratase
O3S71_RS19935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
O3S71_RS19940	COG0861	Integral membrane protein TerC family
O3S71_RS19945	COG2116	formate transmembrane transporter activity
O3S71_RS19955	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
O3S71_RS19975	COG2186	Transcriptional regulator
O3S71_RS19980	COG5002	protein histidine kinase activity
O3S71_RS19985	COG0745	RESPONSE REGULATOR receiver
O3S71_RS19995	COG3835	regulator
O3S71_RS20000	COG0277	FAD linked oxidase domain protein
O3S71_RS20005	COG0247	lactate metabolic process
O3S71_RS20010	COG2340	Cysteine-rich secretory protein family
O3S71_RS20020	COG0564	pseudouridine synthase activity
O3S71_RS20030	COG2409	Drug exporters of the RND superfamily
O3S71_RS20035	COG0671	phosphoesterase, PA-phosphatase related
O3S71_RS20045	COG1177	transmembrane transport
O3S71_RS20050	COG1176	ABC-type spermidine putrescine transport system, permease component I
O3S71_RS20060	COG1012	belongs to the aldehyde dehydrogenase family
O3S71_RS20095	COG0681	Belongs to the peptidase S26 family
O3S71_RS20100	COG1686	Belongs to the peptidase S11 family
O3S71_RS20130	COG1668	transmembrane transport
O3S71_RS20135	COG4152	abc transporter atp-binding protein
O3S71_RS20170	COG1476	TRANSCRIPTIONal
O3S71_RS20180	COG0508	dehydrogenase complex catalyzes the overall conversion of
O3S71_RS20235	COG5634	Uncharacterized conserved protein (DUF2278)
O3S71_RS20240	COG1620	l-lactate permease
O3S71_RS20275	COG0512	Glutamine amidotransferase of anthranilate synthase
O3S71_RS20275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
O3S71_RS20285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O3S71_RS20290	COG5492	domain, Protein
O3S71_RS20310	COG2382	esterase
O3S71_RS20320	COG2153	protein acetylation
O3S71_RS20365	COG1091	dTDP-4-dehydrorhamnose reductase activity
O3S71_RS20380	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
O3S71_RS20400	COG0457	Tetratricopeptide repeat
O3S71_RS20400	COG0463	Glycosyl transferase, family 2
O3S71_RS20420	COG1216	Glycosyl transferase, family 2
O3S71_RS20425	COG0772	Belongs to the SEDS family
O3S71_RS20440	COG0564	pseudouridine synthase activity
O3S71_RS20450	COG2357	RelA SpoT domain protein
O3S71_RS20460	COG4116	CYTH
O3S71_RS20465	COG2346	COG2346, Truncated hemoglobins
O3S71_RS20480	COG1164	Oligoendopeptidase f
O3S71_RS20500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O3S71_RS20510	COG0861	Integral membrane protein TerC family
O3S71_RS20525	COG4166	transmembrane transport
O3S71_RS20530	COG0534	Mate efflux family protein
O3S71_RS20535	COG4608	Belongs to the ABC transporter superfamily
O3S71_RS20540	COG0444	Belongs to the ABC transporter superfamily
O3S71_RS20545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O3S71_RS20550	COG0601	transmembrane transport
O3S71_RS20555	COG4166	transmembrane transport
O3S71_RS20565	COG0180	Tryptophanyl-tRNA synthetase
O3S71_RS20575	COG5504	Zn-dependent protease
O3S71_RS20580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
O3S71_RS20585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
O3S71_RS20600	COG2267	carboxylic ester hydrolase activity
O3S71_RS20620	COG0561	phosphatase activity
O3S71_RS20635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O3S71_RS20650	COG2996	Protein conserved in bacteria
O3S71_RS20670	COG0004	ammonium transporteR
O3S71_RS20675	COG0753	catalase activity
O3S71_RS20685	COG0367	asparagine synthase
O3S71_RS20710	COG0179	Fumarylacetoacetate (FAA) hydrolase
O3S71_RS20770	COG0398	Pfam SNARE associated Golgi protein
O3S71_RS20775	COG4903	ComK protein
O3S71_RS20790	COG1278	Cold shock
O3S71_RS20805	COG2224	Isocitrate lyase
O3S71_RS20810	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
O3S71_RS20820	COG3693	PFAM glycoside hydrolase, family 10
O3S71_RS20825	COG0697	spore germination
O3S71_RS20830	COG0840	transmembrane signaling receptor activity
O3S71_RS20835	COG0501	Belongs to the peptidase M48B family
O3S71_RS20855	COG0745	RESPONSE REGULATOR receiver
O3S71_RS20860	COG2205	protein histidine kinase activity
O3S71_RS20875	COG3708	Transcriptional regulator
O3S71_RS20875	COG2207	Transcriptional regulator
O3S71_RS20880	COG1595	DNA-templated transcription, initiation
O3S71_RS20890	COG1078	dGTPase activity
O3S71_RS20895	COG1408	metallophosphoesterase
O3S71_RS20900	COG1073	alpha beta
O3S71_RS20930	COG0318	PFAM AMP-dependent synthetase and ligase
O3S71_RS20940	COG0095	Lipoate-protein ligase
O3S71_RS20945	COG1234	tRNA 3'-trailer cleavage
O3S71_RS20955	COG1609	Transcriptional regulator
O3S71_RS20980	COG1511	domain protein
O3S71_RS20985	COG1309	transcriptional regulator
O3S71_RS21010	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
O3S71_RS21025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O3S71_RS21030	COG2329	Antibiotic biosynthesis monooxygenase
O3S71_RS21035	COG3428	Bacterial PH domain
O3S71_RS21040	COG3402	PFAM membrane-flanked domain
O3S71_RS21045	COG0697	spore germination
O3S71_RS21080	COG3428	Bacterial PH domain
O3S71_RS21085	COG3402	PFAM membrane-flanked domain
O3S71_RS21095	COG1309	transcriptional regulator
O3S71_RS21110	COG4473	ABC transporter
O3S71_RS21115	COG1131	(ABC) transporter
O3S71_RS21120	COG0537	adenosine 5'-monophosphoramidase activity
O3S71_RS21125	COG4980	gas vesicle protein
O3S71_RS21150	COG3973	AAA domain
O3S71_RS21185	COG1404	Belongs to the peptidase S8 family
O3S71_RS21200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
O3S71_RS21210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
O3S71_RS21215	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
O3S71_RS21220	COG3620	sequence-specific DNA binding
O3S71_RS21225	COG2140	Oxalate decarboxylase
O3S71_RS21250	COG2267	carboxylic ester hydrolase activity
O3S71_RS21275	COG0346	lactoylglutathione lyase activity
O3S71_RS21280	COG0346	lactoylglutathione lyase activity
O3S71_RS21285	COG1280	lysine exporter protein (LysE YggA)
O3S71_RS21300	COG4717	serine-type aminopeptidase activity
O3S71_RS21305	COG0420	3'-5' exonuclease activity
O3S71_RS21325	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
O3S71_RS21380	COG5002	protein histidine kinase activity
O3S71_RS21380	COG0784	Response regulator, receiver
O3S71_RS21380	COG2205	protein histidine kinase activity
O3S71_RS21385	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
O3S71_RS21390	COG2208	phosphoserine phosphatase activity
O3S71_RS21400	COG1191	sigma factor activity
O3S71_RS21425	COG3237	CsbD-like
O3S71_RS21480	COG2373	Large extracellular alpha-helical protein
O3S71_RS21505	COG1959	2 iron, 2 sulfur cluster binding
O3S71_RS21515	COG2376	Dihydroxyacetone kinase
O3S71_RS21525	COG2376	Dihydroxyacetone kinase
O3S71_RS21540	COG1183	phosphatidylcholine synthase activity
O3S71_RS21555	COG1309	transcriptional regulator
O3S71_RS21560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O3S71_RS21560	COG3320	Male sterility
O3S71_RS21670	COG0477	Major facilitator Superfamily
O3S71_RS21710	COG0305	Participates in initiation and elongation during chromosome replication
O3S71_RS21730	COG0513	Belongs to the DEAD box helicase family
O3S71_RS21735	COG0494	nUDIX hydrolase
O3S71_RS21740	COG3181	Tripartite tricarboxylate transporter family receptor
O3S71_RS21745	COG4565	transcriptional regulatory protein
O3S71_RS21750	COG3290	protein histidine kinase activity
O3S71_RS21810	COG1609	Transcriptional regulator
O3S71_RS21815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O3S71_RS21815	COG1263	PTS System
O3S71_RS21820	COG1621	beta-fructofuranosidase activity
O3S71_RS21825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
O3S71_RS21840	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS21845	COG2252	PERMEase
O3S71_RS21855	COG1136	(ABC) transporter
O3S71_RS21880	COG1846	Transcriptional regulator
O3S71_RS21885	COG2814	Major facilitator Superfamily
O3S71_RS21890	COG2205	protein histidine kinase activity
O3S71_RS21930	COG0351	phosphomethylpyrimidine kinase
O3S71_RS21935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
O3S71_RS21945	COG2104	thiamine diphosphate biosynthetic process
O3S71_RS21950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
O3S71_RS21955	COG0352	thiamine-phosphate diphosphorylase activity
O3S71_RS21960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
O3S71_RS21965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
O3S71_RS21970	COG1116	anion transmembrane transporter activity
O3S71_RS21975	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
O3S71_RS21995	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
O3S71_RS22115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
O3S71_RS22125	COG0581	inorganic phosphate transmembrane transporter activity
O3S71_RS22130	COG0573	inorganic phosphate transmembrane transporter activity
O3S71_RS22135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
O3S71_RS22140	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
O3S71_RS22140	COG1918	ferrous iron import across plasma membrane
O3S71_RS22145	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
O3S71_RS22150	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
O3S71_RS22165	COG0531	amino acid
O3S71_RS22170	COG0697	spore germination
O3S71_RS22175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O3S71_RS22190	COG4990	cell redox homeostasis
O3S71_RS22195	COG0833	amino acid
O3S71_RS22205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
O3S71_RS22220	COG0569	domain protein
O3S71_RS22220	COG0475	glutathione-regulated potassium exporter activity
O3S71_RS22230	COG2153	protein acetylation
O3S71_RS22245	COG2252	PERMEase
O3S71_RS22250	COG1113	amino acid transport
O3S71_RS22265	COG1114	Component of the transport system for branched-chain amino acids
O3S71_RS22270	COG3104	oligopeptide transport
O3S71_RS22290	COG1476	TRANSCRIPTIONal
O3S71_RS22295	COG1388	LysM domain
O3S71_RS22295	COG3584	3D domain protein
O3S71_RS22300	COG0840	transmembrane signaling receptor activity
O3S71_RS22350	COG1063	alcohol dehydrogenase
O3S71_RS22380	COG1879	ABC-type sugar transport system periplasmic component
O3S71_RS22385	COG1172	Belongs to the binding-protein-dependent transport system permease family
O3S71_RS22425	COG5632	N-Acetylmuramoyl-L-alanine amidase
O3S71_RS22570	COG3331	DNA recombination
O3S71_RS22675	COG4974	Belongs to the 'phage' integrase family
O3S71_RS22690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
O3S71_RS22695	COG1609	Transcriptional regulator
O3S71_RS22700	COG0477	Major facilitator Superfamily
O3S71_RS22705	COG1846	Transcriptional regulator
O3S71_RS22710	COG2271	Major facilitator Superfamily
O3S71_RS22725	COG0659	secondary active sulfate transmembrane transporter activity
O3S71_RS22740	COG5002	protein histidine kinase activity
O3S71_RS22745	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
O3S71_RS22750	COG2378	regulation of single-species biofilm formation
O3S71_RS22760	COG1595	DNA-templated transcription, initiation
O3S71_RS22775	COG0833	amino acid
O3S71_RS22780	COG0765	amino acid transport
O3S71_RS22785	COG0765	amino acid transport
O3S71_RS22790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O3S71_RS22795	COG1126	abc transporter atp-binding protein
O3S71_RS22800	COG1115	amino acid carrier protein
O3S71_RS22805	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
O3S71_RS22810	COG0697	spore germination
O3S71_RS22825	COG0366	Alpha amylase catalytic
O3S71_RS22830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O3S71_RS22830	COG1263	PTS System
O3S71_RS22835	COG2188	Transcriptional regulator
O3S71_RS22840	COG0531	amino acid
O3S71_RS22860	COG0714	Associated with various cellular activities
O3S71_RS22865	COG4548	von Willebrand factor, type A
O3S71_RS22875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O3S71_RS22880	COG0156	8-amino-7-oxononanoate synthase activity
O3S71_RS22895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O3S71_RS22900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O3S71_RS22905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O3S71_RS22910	COG3104	oligopeptide transport
O3S71_RS22925	COG1620	l-lactate permease
O3S71_RS22930	COG1027	Aspartate ammonia-lyase
O3S71_RS22935	COG1253	flavin adenine dinucleotide binding
O3S71_RS22940	COG0346	lactoylglutathione lyase activity
O3S71_RS22945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O3S71_RS22950	COG1316	TRANSCRIPTIONal
O3S71_RS22955	COG2720	vancomycin resistance protein
O3S71_RS22975	COG3227	Zinc metalloprotease (Elastase)
O3S71_RS22990	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
O3S71_RS22995	COG2217	Heavy metal translocating P-type atpase
O3S71_RS23000	COG0640	Transcriptional regulator
O3S71_RS23005	COG0531	amino acid
O3S71_RS23020	COG2427	Protein of unknown function (DUF1641)
O3S71_RS23025	COG3383	formate dehydrogenase (NAD+) activity
O3S71_RS23030	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
O3S71_RS23055	COG5002	protein histidine kinase activity
O3S71_RS23065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O3S71_RS23080	COG0281	malic enzyme
O3S71_RS23085	COG3493	citrate carrier protein
O3S71_RS23090	COG4565	transcriptional regulatory protein
O3S71_RS23095	COG3290	protein histidine kinase activity
O3S71_RS23105	COG4990	cell redox homeostasis
O3S71_RS23115	COG5002	protein histidine kinase activity
O3S71_RS23120	COG0745	RESPONSE REGULATOR receiver
O3S71_RS23125	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
O3S71_RS23135	COG0395	ABC-type sugar transport system, permease component
O3S71_RS23140	COG1175	transmembrane transport
O3S71_RS23145	COG3842	ATPase activity
O3S71_RS23150	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
O3S71_RS23175	COG2851	Citrate transporter
O3S71_RS23180	COG4565	transcriptional regulatory protein
O3S71_RS23185	COG3290	protein histidine kinase activity
O3S71_RS23195	COG2268	Band 7 protein
O3S71_RS23200	COG1585	Membrane protein implicated in regulation of membrane protease activity
O3S71_RS23210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
O3S71_RS23225	COG2766	serine protein kinase
O3S71_RS23235	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
O3S71_RS23260	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
O3S71_RS23380	COG0735	belongs to the Fur family
O3S71_RS23385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
O3S71_RS23405	COG4555	ABC transporter
O3S71_RS23415	COG0067	glutamate synthase
O3S71_RS23415	COG0069	glutamate synthase activity
O3S71_RS23415	COG0070	glutamate synthase
O3S71_RS23420	COG4129	membrane
O3S71_RS23425	COG1132	(ABC) transporter
O3S71_RS23450	COG1194	a g-specific adenine glycosylase
O3S71_RS23455	COG1988	membrane-bound metal-dependent
O3S71_RS23485	COG1090	epimerase
O3S71_RS23490	COG1228	amidohydrolase
O3S71_RS23510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
O3S71_RS23525	COG0463	Glycosyl transferase, family 2
O3S71_RS23530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O3S71_RS23530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
O3S71_RS23540	COG1216	Glycosyl transferase, family 2
O3S71_RS23555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O3S71_RS23560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O3S71_RS23560	COG1263	PTS System
O3S71_RS23590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O3S71_RS23595	COG0833	amino acid
O3S71_RS23605	COG3829	transcription factor binding
O3S71_RS23625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
O3S71_RS23630	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
O3S71_RS23650	COG0535	radical SAM domain protein
O3S71_RS23660	COG0387	Pfam Sodium calcium exchanger
O3S71_RS23665	COG3871	stress protein (general stress protein 26)
O3S71_RS23680	COG0586	Pfam SNARE associated Golgi protein
O3S71_RS23690	COG0681	Belongs to the peptidase S26 family
O3S71_RS23700	COG0697	spore germination
O3S71_RS23705	COG2217	Heavy metal translocating P-type atpase
O3S71_RS23710	COG1295	ribonuclease BN
O3S71_RS23720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
O3S71_RS23735	COG3853	Toxic anion resistance protein (TelA)
O3S71_RS23745	COG0861	Integral membrane protein TerC family
O3S71_RS23750	COG2310	stress, protein
O3S71_RS23755	COG2310	stress, protein
O3S71_RS23760	COG2310	stress, protein
O3S71_RS23790	COG2270	Major facilitator Superfamily
O3S71_RS23840	COG1116	anion transmembrane transporter activity
O3S71_RS23845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
O3S71_RS23850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
O3S71_RS23870	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
O3S71_RS23900	COG1263	PTS System
O3S71_RS23900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O3S71_RS23900	COG2190	(PTS) system
O3S71_RS23905	COG0366	Alpha amylase catalytic
O3S71_RS23910	COG0277	FAD linked oxidase domain protein
O3S71_RS23920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
O3S71_RS23925	COG0549	Belongs to the carbamate kinase family
O3S71_RS23950	COG0840	transmembrane signaling receptor activity
O3S71_RS23960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O3S71_RS23965	COG0765	amino acid transport
O3S71_RS23990	COG2814	Major facilitator Superfamily
O3S71_RS24000	COG3541	Predicted nucleotidyltransferase
O3S71_RS24020	COG5002	protein histidine kinase activity
O3S71_RS24045	COG0166	Belongs to the GPI family
O3S71_RS24060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O3S71_RS24065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O3S71_RS24070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O3S71_RS24080	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
O3S71_RS24090	COG0450	alkyl hydroperoxide reductase
O3S71_RS24105	COG1473	amidohydrolase
O3S71_RS24110	COG1757	Na H antiporter
O3S71_RS24135	COG4807	Protein conserved in bacteria
O3S71_RS24140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
O3S71_RS24150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O3S71_RS24165	COG2309	aminopeptidase activity
O3S71_RS24175	COG2076	Multidrug Resistance protein
O3S71_RS24180	COG1012	belongs to the aldehyde dehydrogenase family
O3S71_RS24190	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
O3S71_RS24195	COG0546	phosphoglycolate phosphatase activity
O3S71_RS24200	COG1597	lipid kinase activity
O3S71_RS24220	COG4682	membrane
O3S71_RS24225	COG1846	Transcriptional regulator
O3S71_RS24230	COG0003	Pfam Anion-transporting ATPase
O3S71_RS24245	COG1464	Belongs to the NlpA lipoprotein family
O3S71_RS24250	COG2011	ABC-type metal ion transport system permease component
O3S71_RS24260	COG1335	isochorismatase
O3S71_RS24275	COG4851	CamS sex pheromone cAM373 precursor
O3S71_RS24285	COG0210	DNA helicase
O3S71_RS24310	COG0151	Belongs to the GarS family
O3S71_RS24320	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
O3S71_RS24330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
O3S71_RS24345	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
O3S71_RS24355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
O3S71_RS24360	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
O3S71_RS24365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
O3S71_RS24395	COG0697	spore germination
O3S71_RS24415	COG0745	RESPONSE REGULATOR receiver
O3S71_RS24420	COG2205	protein histidine kinase activity
O3S71_RS24485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
O3S71_RS24510	COG5002	protein histidine kinase activity
O3S71_RS24520	COG2252	PERMEase
O3S71_RS24540	COG1266	CAAX protease self-immunity
O3S71_RS24555	COG0488	(ABC) transporter
O3S71_RS24565	COG0456	acetyltransferase
O3S71_RS24570	COG1214	PFAM Peptidase M22, glycoprotease
O3S71_RS24575	COG0802	atpase or kinase
O3S71_RS24675	COG2183	response to ionizing radiation
O3S71_RS24680	COG2337	Toxic component of a toxin-antitoxin (TA) module
O3S71_RS24685	COG0864	Transcriptional regulator
O3S71_RS24690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
O3S71_RS24695	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
O3S71_RS24705	COG0705	Rhomboid family
O3S71_RS24710	COG4294	response to UV
O3S71_RS24720	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
O3S71_RS24730	COG2814	Major facilitator Superfamily
O3S71_RS24735	COG0531	amino acid
O3S71_RS24745	COG0179	Fumarylacetoacetate (FAA) hydrolase
O3S71_RS24750	COG3185	4-Hydroxyphenylpyruvate dioxygenase
O3S71_RS24780	COG0561	phosphatase activity
O3S71_RS24785	COG4608	Belongs to the ABC transporter superfamily
O3S71_RS24790	COG0444	Belongs to the ABC transporter superfamily
O3S71_RS24795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O3S71_RS24800	COG0601	transmembrane transport
O3S71_RS24805	COG0747	negative chemotaxis
O3S71_RS24815	COG0488	(ABC) transporter
O3S71_RS24865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O3S71_RS24875	COG1609	Transcriptional regulator
O3S71_RS24885	COG0204	Acyl-transferase
O3S71_RS24900	COG0697	spore germination
O3S71_RS24915	COG1910	domain protein
O3S71_RS24920	COG0725	ABC transporter, periplasmic molybdate-binding protein
O3S71_RS24925	COG4149	molybdate abc transporter
O3S71_RS24945	COG0656	L-ascorbic acid biosynthetic process
O3S71_RS24950	COG4166	transmembrane transport
O3S71_RS24955	COG4166	transmembrane transport
O3S71_RS24970	COG4166	transmembrane transport
O3S71_RS24975	COG4608	Belongs to the ABC transporter superfamily
O3S71_RS24980	COG0444	Belongs to the ABC transporter superfamily
O3S71_RS24985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O3S71_RS24990	COG0601	transmembrane transport
O3S71_RS25010	COG2814	Major facilitator Superfamily
O3S71_RS25020	COG2271	Major facilitator Superfamily
O3S71_RS25025	COG0277	FAD linked oxidase domain protein
O3S71_RS25035	COG0604	alcohol dehydrogenase
O3S71_RS25040	COG1464	Belongs to the NlpA lipoprotein family
O3S71_RS25045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
O3S71_RS25050	COG2011	ABC-type metal ion transport system permease component
O3S71_RS25055	COG1028	Short-chain dehydrogenase reductase Sdr
O3S71_RS25090	COG4856	YbbR-like protein
O3S71_RS25095	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
O3S71_RS25175	COG0726	polysaccharide deacetylase
O3S71_RS25180	COG2194	sulfuric ester hydrolase activity
O3S71_RS25190	COG0489	protein tyrosine kinase activity
O3S71_RS25195	COG0860	N-Acetylmuramoyl-L-alanine amidase
O3S71_RS25220	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
O3S71_RS25255	COG0257	Belongs to the bacterial ribosomal protein bL36 family
O3S71_RS25265	COG0024	Methionine aminopeptidase
O3S71_RS25275	COG0201	protein transport
O3S71_RS25335	COG0255	Belongs to the universal ribosomal protein uL29 family
O3S71_RS25375	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
O3S71_RS25380	COG0051	transcription antitermination factor activity, RNA binding
O3S71_RS25400	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
O3S71_RS25405	COG1358	cellular component organization or biogenesis
O3S71_RS25410	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
O3S71_RS25420	COG2813	Specifically methylates the guanine in position
O3S71_RS25440	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
O3S71_RS25445	COG0250	Participates in transcription elongation, termination and antitermination
O3S71_RS25450	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
O3S71_RS25465	COG3688	RNA-binding protein containing a PIN domain
O3S71_RS25470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
O3S71_RS25485	COG1045	serine acetyltransferase
O3S71_RS25505	COG4956	integral membrane protein (PIN domain superfamily)
O3S71_RS25515	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
O3S71_RS25520	COG0542	response to heat
O3S71_RS25530	COG3880	PFAM UvrB UvrC protein
O3S71_RS25620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
O3S71_RS25625	COG1396	sequence-specific DNA binding
O3S71_RS25630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
O3S71_RS25635	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
O3S71_RS25640	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
O3S71_RS25645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O3S71_RS25650	COG0512	Glutamine amidotransferase of anthranilate synthase
O3S71_RS25655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
O3S71_RS25660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
O3S71_RS25675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
O3S71_RS25680	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
O3S71_RS25690	COG2208	phosphoserine phosphatase activity
O3S71_RS25705	COG1098	S1 RNA binding domain
O3S71_RS25725	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
O3S71_RS25730	COG3956	TIGRFAM MazG family protein
O3S71_RS25735	COG2244	polysaccharide biosynthetic process
O3S71_RS25740	COG2002	toxin-antitoxin pair type II binding
O3S71_RS25745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
O3S71_RS25775	COG0251	oxidation-reduction process
O3S71_RS25780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
O3S71_RS25795	COG4466	Protein conserved in bacteria
O3S71_RS25815	COG0084	hydrolase, TatD family'
O3S71_RS25825	COG2002	toxin-antitoxin pair type II binding
O3S71_RS25830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
O3S71_RS25840	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
O3S71_RS25850	COG1774	PSP1 C-terminal conserved region
O3S71_RS25855	COG0470	DNA polymerase III
O3S71_RS25865	COG1982	Orn Lys Arg decarboxylase major
O3S71_RS25925	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
O3S71_RS25935	COG0590	tRNA wobble adenosine to inosine editing
O3S71_RS25940	COG1335	isochorismatase
O3S71_RS25945	COG1428	Deoxynucleoside kinase
O3S71_RS25950	COG1428	Deoxynucleoside kinase
O3S71_RS25980	COG1686	Belongs to the peptidase S11 family
O3S71_RS25985	COG0517	IMP dehydrogenase activity
O3S71_RS25985	COG0516	GMP reductase activity
O3S71_RS26020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
O3S71_RS26025	COG0187	DNA topoisomerase II activity
O3S71_RS26035	COG2501	S4 domain
O3S71_RS26040	COG0592	DNA-directed DNA polymerase activity
O3S71_RS26050	COG0230	Belongs to the bacterial ribosomal protein bL34 family
O3S71_RS26065	COG1847	R3H domain protein
O3S71_RS26090	COG1192	Involved in chromosome partitioning
O3S71_RS26095	COG1475	DNA binding
O3S71_RS26105	COG0668	transmembrane transport
O3S71_RS26110	COG4481	Protein conserved in bacteria
O3S71_RS26115	COG0012	GTP binding
O3S71_RS26125	COG0629	single-stranded DNA binding
O3S71_RS26135	COG4241	membrane
O3S71_RS26140	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
O3S71_RS26150	COG0305	Participates in initiation and elongation during chromosome replication
O3S71_RS26180	COG0745	RESPONSE REGULATOR receiver
O3S71_RS26185	COG5002	protein histidine kinase activity
O3S71_RS26195	COG4853	Protein conserved in bacteria
O3S71_RS26200	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
O3S71_RS26205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O3S71_RS26220	COG5002	protein histidine kinase activity
O3S71_RS26235	COG1164	Oligoendopeptidase f
O3S71_RS26255	COG1272	protein, Hemolysin III
O3S71_RS26260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
O3S71_RS26290	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
O3S71_RS26295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
O3S71_RS26300	COG2814	Major facilitator Superfamily
O3S71_RS26305	COG3275	phosphorelay sensor kinase activity
O3S71_RS26325	COG0628	permease
O3S71_RS26330	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
O3S71_RS26330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
O3S71_RS26335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
O3S71_RS26340	COG1309	transcriptional regulator
O3S71_RS26345	COG0488	(ABC) transporter
O3S71_RS26350	COG1309	transcriptional regulator
O3S71_RS26360	COG0463	Glycosyl transferase, family 2
O3S71_RS26375	COG1216	Glycosyl transferase, family 2
O3S71_RS26390	COG1216	Glycosyl transferase, family 2
O3S71_RS26395	COG1607	acyl-coa hydrolase
O3S71_RS26405	COG0840	transmembrane signaling receptor activity
O3S71_RS26420	COG0438	transferase activity, transferring glycosyl groups
O3S71_RS26430	COG0477	Major facilitator Superfamily
O3S71_RS26435	COG3279	Response regulator of the LytR AlgR family
O3S71_RS26440	COG1966	Carbon starvation protein
O3S71_RS26445	COG2879	small protein
O3S71_RS26450	COG3706	GGDEF domain
O3S71_RS26455	COG0351	phosphomethylpyrimidine kinase
O3S71_RS26460	COG4585	Histidine kinase
O3S71_RS26460	COG2203	Gaf domain
O3S71_RS26465	COG2197	response regulator
O3S71_RS26475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
O3S71_RS26480	COG1011	Hydrolase
O3S71_RS26485	COG2873	o-acetylhomoserine
O3S71_RS26495	COG0460	homoserine dehydrogenase
O3S71_RS26505	COG1609	Transcriptional regulator
O3S71_RS26510	COG2755	lipolytic protein G-D-S-L family
O3S71_RS26515	COG1131	(ABC) transporter
O3S71_RS26520	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
O3S71_RS26530	COG2814	Major facilitator Superfamily
O3S71_RS26535	COG0561	phosphatase activity
O3S71_RS26540	COG2233	PERMEase
O3S71_RS26545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
O3S71_RS26555	COG2363	Small membrane protein
O3S71_RS26565	COG3773	Cell wall hydrolase
O3S71_RS26580	COG0280	phosphate acetyltransferase
O3S71_RS26600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O3S71_RS26605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O3S71_RS26610	COG1120	ATPase activity
O3S71_RS26615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O3S71_RS26620	COG1078	dGTPase activity
O3S71_RS26630	COG1994	Peptidase M50
O3S71_RS26640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O3S71_RS26645	COG0584	glycerophosphoryl diester phosphodiesterase
O3S71_RS26650	COG0789	Transcriptional regulator
O3S71_RS26655	COG2814	Major facilitator Superfamily
O3S71_RS26680	COG1619	proteins homologs of microcin C7 resistance protein MccF
O3S71_RS26685	COG4506	Protein conserved in bacteria
O3S71_RS26695	COG1595	DNA-templated transcription, initiation
O3S71_RS26715	COG2234	aminopeptidase activity
O3S71_RS26725	COG0024	Methionine aminopeptidase
O3S71_RS26730	COG1131	(ABC) transporter
O3S71_RS26735	COG0842	Transport permease protein
O3S71_RS26740	COG4585	Histidine kinase
O3S71_RS26745	COG2197	response regulator
O3S71_RS26750	COG3227	Zinc metalloprotease (Elastase)
O3S71_RS26765	COG3300	MHYT domain
O3S71_RS26765	COG5001	Diguanylate cyclase
O3S71_RS26775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O3S71_RS26780	COG0247	lactate metabolic process
O3S71_RS26780	COG2181	nitrate reductase activity
O3S71_RS26785	COG0183	Belongs to the thiolase family
O3S71_RS26790	COG1250	3-hydroxyacyl-CoA dehydrogenase
O3S71_RS26795	COG1960	acyl-CoA dehydrogenase activity
O3S71_RS26800	COG1960	acyl-CoA dehydrogenase activity
O3S71_RS26820	COG4821	SIS domain
O3S71_RS26840	COG1494	fructose-1,6-bisphosphatase
O3S71_RS26845	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
O3S71_RS26880	COG0009	L-threonylcarbamoyladenylate synthase
O3S71_RS26900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
O3S71_RS26905	COG2259	Doxx family
O3S71_RS26910	COG2190	(PTS) system
O3S71_RS26920	COG0698	ribose 5-phosphate isomerase
O3S71_RS26955	COG0356	it plays a direct role in the translocation of protons across the membrane
O3S71_RS27005	COG3300	MHYT domain
O3S71_RS27005	COG5001	Diguanylate cyclase
O3S71_RS27020	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
O3S71_RS27040	COG0839	Belongs to the complex I subunit 6 family
O3S71_RS27050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
O3S71_RS27055	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
O3S71_RS27060	COG1007	ATP synthesis coupled electron transport
O3S71_RS27065	COG4836	Membrane
O3S71_RS27080	COG2385	sporulation resulting in formation of a cellular spore
O3S71_RS27085	COG3279	Response regulator of the LytR AlgR family
O3S71_RS27100	COG0739	heme binding
O3S71_RS27110	COG1609	Transcriptional regulator
O3S71_RS27125	COG0489	protein tyrosine kinase activity
O3S71_RS27130	COG3944	biosynthesis protein
O3S71_RS27135	COG0489	protein tyrosine kinase activity
O3S71_RS27140	COG4464	protein tyrosine phosphatase activity
O3S71_RS27160	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
O3S71_RS27165	COG1215	transferase activity, transferring glycosyl groups
O3S71_RS27190	COG1215	transferase activity, transferring glycosyl groups
O3S71_RS27200	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
O3S71_RS27210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
O3S71_RS27215	COG1316	TRANSCRIPTIONal
O3S71_RS27225	COG0745	RESPONSE REGULATOR receiver
O3S71_RS27230	COG5002	protein histidine kinase activity
O3S71_RS27255	COG1136	(ABC) transporter
O3S71_RS27260	COG0577	efflux transmembrane transporter activity
O3S71_RS27300	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
O3S71_RS27305	COG4715	Zinc finger, swim domain protein
O3S71_RS27330	COG1388	LysM domain
O3S71_RS27330	COG3584	3D domain protein
O3S71_RS27335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
O3S71_RS27340	COG1215	transferase activity, transferring glycosyl groups
O3S71_RS27355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O3S71_RS27360	COG1388	LysM domain
O3S71_RS27360	COG0791	NLP P60 protein
O3S71_RS27370	COG1368	sulfuric ester hydrolase activity
O3S71_RS27380	COG2389	metal-binding protein
O3S71_RS27390	COG1620	l-lactate permease
O3S71_RS27400	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
O3S71_RS27405	COG1294	oxidase, subunit
O3S71_RS27410	COG1271	oxidase subunit
O3S71_RS27425	COG0583	DNA-binding transcription factor activity
O3S71_RS27430	COG1511	domain protein
O3S71_RS27445	COG1301	dicarboxylic acid transport
O3S71_RS27450	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O3S71_RS27460	COG1447	Phosphotransferase system cellobiose-specific component IIA
O3S71_RS27470	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
O3S71_RS27480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O3S71_RS27485	COG1447	Phosphotransferase system cellobiose-specific component IIA
O3S71_RS27490	COG1486	melibiose metabolic process
O3S71_RS27510	COG3933	PFAM sigma-54 factor interaction domain-containing protein
O3S71_RS27510	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
O3S71_RS27520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
O3S71_RS27525	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
O3S71_RS27530	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
O3S71_RS27535	COG1316	TRANSCRIPTIONal
O3S71_RS27540	COG1739	Uncharacterized protein family UPF0029
O3S71_RS27545	COG1307	EDD domain protein, DegV family
O3S71_RS27550	COG1733	regulation of RNA biosynthetic process
O3S71_RS27555	COG0791	NLP P60 protein
O3S71_RS27555	COG1388	LysM domain
O3S71_RS27560	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
O3S71_RS27565	COG1040	competence protein
O3S71_RS27570	COG1278	Cold shock
O3S71_RS27575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
O3S71_RS27615	COG1131	(ABC) transporter
O3S71_RS27640	COG2884	Cell division ATP-binding protein ftsE
O3S71_RS27645	COG2177	Part of the ABC transporter FtsEX involved in
O3S71_RS27650	COG3409	Peptidoglycan-binding domain 1 protein
O3S71_RS27650	COG0793	Belongs to the peptidase S41A family
O3S71_RS27655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O3S71_RS27660	COG1132	(ABC) transporter
O3S71_RS27670	COG0655	NAD(P)H dehydrogenase (quinone) activity
O3S71_RS27680	COG0583	DNA-binding transcription factor activity
O3S71_RS27700	COG0789	Transcriptional regulator
O3S71_RS27715	COG0556	nucleotide-excision repair
O3S71_RS27720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
O3S71_RS27730	COG1950	PFAM Membrane protein of
O3S71_RS27750	COG0110	maltose O-acetyltransferase activity
O3S71_RS27755	COG0457	Tetratricopeptide repeat
O3S71_RS27760	COG0492	ferredoxin-NADP+ reductase activity
O3S71_RS27770	COG1051	belongs to the nudix hydrolase family
O3S71_RS27780	COG0391	Required for morphogenesis under gluconeogenic growth conditions
O3S71_RS27790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
O3S71_RS27800	COG2323	membrane
O3S71_RS27815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
O3S71_RS27880	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
O3S71_RS27895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
O3S71_RS27930	COG1346	cytolysis
O3S71_RS27935	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
O3S71_RS27940	COG1647	Serine aminopeptidase, S33
O3S71_RS27945	COG0582	viral genome integration into host DNA
O3S71_RS27960	COG1396	sequence-specific DNA binding
O3S71_RS28045	COG0582	viral genome integration into host DNA
O3S71_RS28250	COG2814	Major facilitator Superfamily
O3S71_RS28325	COG0745	RESPONSE REGULATOR receiver
O3S71_RS28330	COG2205	protein histidine kinase activity
O3S71_RS28335	COG1131	(ABC) transporter
O3S71_RS28355	COG0456	acetyltransferase
O3S71_RS28365	COG0456	acetyltransferase
O3S71_RS28385	COG1309	transcriptional regulator
O3S71_RS28395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
O3S71_RS28400	COG3711	transcriptional antiterminator
O3S71_RS28400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O3S71_RS28405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O3S71_RS28405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O3S71_RS28405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O3S71_RS28410	COG1482	cell wall glycoprotein biosynthetic process
O3S71_RS28575	COG3344	reverse transcriptase
O3S71_RS28595	COG2311	Membrane
O3S71_RS28615	COG1131	(ABC) transporter
O3S71_RS28620	COG1132	(ABC) transporter
O3S71_RS28645	COG0457	Tetratricopeptide repeat
O3S71_RS28670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
O3S71_RS28675	COG0776	regulation of translation
O3S71_RS28685	COG2002	toxin-antitoxin pair type II binding
O3S71_RS28720	COG4166	transmembrane transport
O3S71_RS28740	COG4974	Belongs to the 'phage' integrase family
O3S71_RS28785	COG2801	Transposase and inactivated derivatives
O3S71_RS28840	COG3437	response regulator, receiver
O3S71_RS28910	COG0457	Tetratricopeptide repeat
O3S71_RS29065	COG3409	Peptidoglycan-binding domain 1 protein
O3S71_RS29065	COG5632	N-Acetylmuramoyl-L-alanine amidase
O3S71_RS29215	COG4974	Belongs to the 'phage' integrase family
O3S71_RS29315	COG2162	N-hydroxyarylamine O-acetyltransferase activity
O3S71_RS29325	COG0840	transmembrane signaling receptor activity
O3S71_RS29340	COG2162	N-hydroxyarylamine O-acetyltransferase activity
O3S71_RS29355	COG0657	acetylesterase activity
O3S71_RS29375	COG0457	Tetratricopeptide repeat
O3S71_RS29595	COG3344	reverse transcriptase
O3S71_RS29845	COG3344	reverse transcriptase
O3S71_RS29865	COG2311	Membrane
O3S71_RS29885	COG1131	(ABC) transporter
O3S71_RS29890	COG1132	(ABC) transporter
O3S71_RS29915	COG0457	Tetratricopeptide repeat
O3S71_RS29940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
O3S71_RS29945	COG0776	regulation of translation
O3S71_RS29955	COG2002	toxin-antitoxin pair type II binding
O3S71_RS29990	COG2162	N-hydroxyarylamine O-acetyltransferase activity
O3S71_RS30205	COG2002	toxin-antitoxin pair type II binding
O3S71_RS30305	COG2162	N-hydroxyarylamine O-acetyltransferase activity
O3S71_RS30315	COG3397	chitin binding
O3S71_RS30340	COG3335	DDE superfamily endonuclease
O3S71_RS30385	COG2801	Transposase and inactivated derivatives
O3S71_RS30395	COG3654	unkown
O3S71_RS30405	COG2801	Transposase and inactivated derivatives
O3S71_RS30415	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
O3S71_RS30420	COG0697	spore germination
O3S71_RS30450	COG0457	Tetratricopeptide repeat
O3S71_RS30475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
O3S71_RS30480	COG0776	regulation of translation
O3S71_RS30490	COG2002	toxin-antitoxin pair type II binding
O3S71_RS30525	COG2162	N-hydroxyarylamine O-acetyltransferase activity
O3S71_RS30720	COG0741	lytic transglycosylase activity
O3S71_RS30720	COG0791	NLP P60 protein
O3S71_RS30895	COG1923	regulation of RNA biosynthetic process
O3S71_RS30905	COG0457	Tetratricopeptide repeat
O3S71_RS30970	COG4824	toxin secretion phage lysis holin
O3S71_RS30985	COG3611	Membrane attachment protein
O3S71_RS31030	COG3646	Phage regulatory protein
O3S71_RS31100	COG3331	DNA recombination
O3S71_RS31215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD