locus-tag	class	description
KNN_RS00005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KNN_RS00020	COG1847	R3H domain protein
KNN_RS00045	COG1192	Involved in chromosome partitioning
KNN_RS00050	COG1475	DNA binding
KNN_RS00060	COG0668	transmembrane transport
KNN_RS00065	COG4481	Protein conserved in bacteria
KNN_RS00070	COG0012	GTP binding
KNN_RS00090	COG4241	membrane
KNN_RS00095	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KNN_RS00105	COG0305	Participates in initiation and elongation during chromosome replication
KNN_RS00135	COG0745	RESPONSE REGULATOR receiver
KNN_RS00140	COG5002	protein histidine kinase activity
KNN_RS00150	COG4853	Protein conserved in bacteria
KNN_RS00155	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KNN_RS00160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNN_RS00185	COG5002	protein histidine kinase activity
KNN_RS00195	COG1164	Oligoendopeptidase f
KNN_RS00215	COG1272	protein, Hemolysin III
KNN_RS00220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KNN_RS00240	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KNN_RS00245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KNN_RS00250	COG2814	Major facilitator Superfamily
KNN_RS00275	COG0628	permease
KNN_RS00280	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNN_RS00280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNN_RS00285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KNN_RS00290	COG1309	transcriptional regulator
KNN_RS00295	COG0488	(ABC) transporter
KNN_RS00300	COG0463	Glycosyl transferase, family 2
KNN_RS00305	COG4485	Bacterial membrane protein, YfhO
KNN_RS00315	COG1216	Glycosyl transferase, family 2
KNN_RS00330	COG1216	Glycosyl transferase, family 2
KNN_RS00335	COG1607	acyl-coa hydrolase
KNN_RS00345	COG0840	transmembrane signaling receptor activity
KNN_RS00360	COG0438	transferase activity, transferring glycosyl groups
KNN_RS00370	COG0477	Major facilitator Superfamily
KNN_RS00375	COG3279	Response regulator of the LytR AlgR family
KNN_RS00380	COG1966	Carbon starvation protein
KNN_RS00385	COG2879	small protein
KNN_RS00390	COG3706	GGDEF domain
KNN_RS00395	COG0351	phosphomethylpyrimidine kinase
KNN_RS00400	COG4585	Histidine kinase
KNN_RS00400	COG2203	Gaf domain
KNN_RS00405	COG2197	response regulator
KNN_RS00415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KNN_RS00420	COG1011	Hydrolase
KNN_RS00430	COG2873	o-acetylhomoserine
KNN_RS00440	COG0460	homoserine dehydrogenase
KNN_RS00450	COG1609	Transcriptional regulator
KNN_RS00455	COG2755	lipolytic protein G-D-S-L family
KNN_RS00460	COG1131	(ABC) transporter
KNN_RS00465	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KNN_RS00475	COG2814	Major facilitator Superfamily
KNN_RS00480	COG0561	phosphatase activity
KNN_RS00485	COG2233	PERMEase
KNN_RS00490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KNN_RS00500	COG2363	Small membrane protein
KNN_RS00510	COG3773	Cell wall hydrolase
KNN_RS00525	COG0280	phosphate acetyltransferase
KNN_RS00545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNN_RS00550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNN_RS00555	COG1120	ATPase activity
KNN_RS00560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNN_RS00565	COG1078	dGTPase activity
KNN_RS00575	COG1994	Peptidase M50
KNN_RS00585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNN_RS00590	COG0584	glycerophosphoryl diester phosphodiesterase
KNN_RS00595	COG0789	Transcriptional regulator
KNN_RS00600	COG2814	Major facilitator Superfamily
KNN_RS00625	COG1619	proteins homologs of microcin C7 resistance protein MccF
KNN_RS00630	COG4506	Protein conserved in bacteria
KNN_RS00660	COG2234	aminopeptidase activity
KNN_RS00670	COG0024	Methionine aminopeptidase
KNN_RS00675	COG1131	(ABC) transporter
KNN_RS00680	COG0842	Transport permease protein
KNN_RS00685	COG4585	Histidine kinase
KNN_RS00690	COG2197	response regulator
KNN_RS00695	COG3227	Zinc metalloprotease (Elastase)
KNN_RS00710	COG5001	Diguanylate cyclase
KNN_RS00710	COG3300	MHYT domain
KNN_RS00720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNN_RS00725	COG0247	lactate metabolic process
KNN_RS00725	COG2181	nitrate reductase activity
KNN_RS00730	COG0183	Belongs to the thiolase family
KNN_RS00735	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNN_RS00740	COG1960	acyl-CoA dehydrogenase activity
KNN_RS00745	COG1960	acyl-CoA dehydrogenase activity
KNN_RS00765	COG4821	SIS domain
KNN_RS00785	COG1494	fructose-1,6-bisphosphatase
KNN_RS00790	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KNN_RS00825	COG0009	L-threonylcarbamoyladenylate synthase
KNN_RS00845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KNN_RS00850	COG2259	Doxx family
KNN_RS00865	COG0698	ribose 5-phosphate isomerase
KNN_RS00900	COG0356	it plays a direct role in the translocation of protons across the membrane
KNN_RS00980	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNN_RS01000	COG0839	Belongs to the complex I subunit 6 family
KNN_RS01010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KNN_RS01015	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNN_RS01020	COG1007	ATP synthesis coupled electron transport
KNN_RS01025	COG4836	Membrane
KNN_RS01040	COG2385	sporulation resulting in formation of a cellular spore
KNN_RS01045	COG3279	Response regulator of the LytR AlgR family
KNN_RS01060	COG0739	heme binding
KNN_RS01070	COG1609	Transcriptional regulator
KNN_RS01085	COG0489	protein tyrosine kinase activity
KNN_RS01090	COG3944	biosynthesis protein
KNN_RS01095	COG0489	protein tyrosine kinase activity
KNN_RS01100	COG4464	protein tyrosine phosphatase activity
KNN_RS01105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KNN_RS01110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KNN_RS01115	COG1215	transferase activity, transferring glycosyl groups
KNN_RS01140	COG1215	transferase activity, transferring glycosyl groups
KNN_RS01150	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KNN_RS01155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KNN_RS01160	COG1316	TRANSCRIPTIONal
KNN_RS01170	COG0745	RESPONSE REGULATOR receiver
KNN_RS01175	COG5002	protein histidine kinase activity
KNN_RS01200	COG1136	(ABC) transporter
KNN_RS01205	COG0577	efflux transmembrane transporter activity
KNN_RS01240	COG3547	Transposase (IS116 IS110 IS902 family)
KNN_RS01250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KNN_RS01255	COG4715	Zinc finger, swim domain protein
KNN_RS01280	COG3584	3D domain protein
KNN_RS01280	COG1388	LysM domain
KNN_RS01285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KNN_RS01295	COG1215	transferase activity, transferring glycosyl groups
KNN_RS01305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KNN_RS01310	COG0791	NLP P60 protein
KNN_RS01310	COG1388	LysM domain
KNN_RS01320	COG1368	sulfuric ester hydrolase activity
KNN_RS01330	COG2389	metal-binding protein
KNN_RS01340	COG1620	l-lactate permease
KNN_RS01350	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KNN_RS01355	COG1294	oxidase, subunit
KNN_RS01360	COG1271	oxidase subunit
KNN_RS01370	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KNN_RS01375	COG0583	DNA-binding transcription factor activity
KNN_RS01380	COG1511	domain protein
KNN_RS01395	COG1301	dicarboxylic acid transport
KNN_RS01400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KNN_RS01410	COG1447	Phosphotransferase system cellobiose-specific component IIA
KNN_RS01430	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KNN_RS01435	COG1447	Phosphotransferase system cellobiose-specific component IIA
KNN_RS01440	COG1486	melibiose metabolic process
KNN_RS01460	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KNN_RS01460	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KNN_RS01470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KNN_RS01475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KNN_RS01480	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KNN_RS01485	COG1316	TRANSCRIPTIONal
KNN_RS01490	COG1739	Uncharacterized protein family UPF0029
KNN_RS01495	COG1307	EDD domain protein, DegV family
KNN_RS01500	COG1733	regulation of RNA biosynthetic process
KNN_RS01505	COG0791	NLP P60 protein
KNN_RS01505	COG1388	LysM domain
KNN_RS01510	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KNN_RS01515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KNN_RS01520	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KNN_RS01695	COG4824	toxin secretion phage lysis holin
KNN_RS01700	COG1388	LysM domain
KNN_RS01700	COG3409	Peptidoglycan-binding domain 1 protein
KNN_RS01700	COG5632	N-Acetylmuramoyl-L-alanine amidase
KNN_RS01720	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KNN_RS01725	COG1040	competence protein
KNN_RS01730	COG1278	Cold shock
KNN_RS01735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KNN_RS01745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KNN_RS01755	COG2884	Cell division ATP-binding protein ftsE
KNN_RS01760	COG2177	Part of the ABC transporter FtsEX involved in
KNN_RS01765	COG3409	Peptidoglycan-binding domain 1 protein
KNN_RS01765	COG0793	Belongs to the peptidase S41A family
KNN_RS01770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNN_RS01775	COG1132	(ABC) transporter
KNN_RS01785	COG0488	(ABC) transporter
KNN_RS01790	COG0655	NAD(P)H dehydrogenase (quinone) activity
KNN_RS01800	COG0583	DNA-binding transcription factor activity
KNN_RS01820	COG0789	Transcriptional regulator
KNN_RS01835	COG0556	nucleotide-excision repair
KNN_RS01840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KNN_RS01850	COG1950	PFAM Membrane protein of
KNN_RS01870	COG0110	maltose O-acetyltransferase activity
KNN_RS01875	COG0457	Tetratricopeptide repeat
KNN_RS01880	COG0492	ferredoxin-NADP+ reductase activity
KNN_RS01890	COG1051	belongs to the nudix hydrolase family
KNN_RS01900	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KNN_RS01910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KNN_RS01920	COG2323	membrane
KNN_RS01935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNN_RS01960	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KNN_RS01975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KNN_RS02010	COG1346	cytolysis
KNN_RS02015	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KNN_RS02020	COG1647	Serine aminopeptidase, S33
KNN_RS02025	COG0557	exoribonuclease II activity
KNN_RS02095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS02100	COG0488	(ABC) transporter
KNN_RS02135	COG3290	protein histidine kinase activity
KNN_RS02135	COG0840	transmembrane signaling receptor activity
KNN_RS02140	COG2801	Transposase and inactivated derivatives
KNN_RS02160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KNN_RS02165	COG1252	NADH dehydrogenase
KNN_RS02175	COG1733	regulation of RNA biosynthetic process
KNN_RS02180	COG2814	Major facilitator Superfamily
KNN_RS02185	COG0656	L-ascorbic acid biosynthetic process
KNN_RS02200	COG2910	NAD(P)H-binding
KNN_RS02205	COG1115	amino acid carrier protein
KNN_RS02210	COG1115	amino acid carrier protein
KNN_RS02220	COG2801	Transposase and inactivated derivatives
KNN_RS02225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KNN_RS02230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KNN_RS02240	COG1528	Iron-storage protein
KNN_RS02250	COG1611	Belongs to the LOG family
KNN_RS02265	COG0783	Belongs to the Dps family
KNN_RS02275	COG1115	amino acid carrier protein
KNN_RS02280	COG0490	domain, Protein
KNN_RS02285	COG0475	glutathione-regulated potassium exporter activity
KNN_RS02290	COG0586	Pfam SNARE associated Golgi protein
KNN_RS02310	COG3227	Zinc metalloprotease (Elastase)
KNN_RS02325	COG2151	metal-sulfur cluster biosynthetic enzyme
KNN_RS02330	COG0840	transmembrane signaling receptor activity
KNN_RS02365	COG5002	protein histidine kinase activity
KNN_RS02370	COG0745	RESPONSE REGULATOR receiver
KNN_RS02375	COG1376	ErfK ybiS ycfS ynhG family protein
KNN_RS02385	COG0586	Pfam SNARE associated Golgi protein
KNN_RS02415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNN_RS02440	COG0531	amino acid
KNN_RS02445	COG2814	Major facilitator Superfamily
KNN_RS02460	COG0840	transmembrane signaling receptor activity
KNN_RS02465	COG0011	TIGRFAM Protein of
KNN_RS02480	COG1686	Belongs to the peptidase S11 family
KNN_RS02490	COG1024	Enoyl-CoA hydratase
KNN_RS02490	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNN_RS02495	COG0183	Belongs to the thiolase family
KNN_RS02500	COG1960	acyl-CoA dehydrogenase activity
KNN_RS02505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNN_RS02510	COG1309	transcriptional regulator
KNN_RS02560	COG1393	Belongs to the ArsC family
KNN_RS02570	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KNN_RS02575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KNN_RS02590	COG2011	ABC-type metal ion transport system permease component
KNN_RS02595	COG1464	Belongs to the NlpA lipoprotein family
KNN_RS02600	COG1464	Belongs to the NlpA lipoprotein family
KNN_RS02605	COG0396	ATPase activity
KNN_RS02610	COG0719	Fe-S assembly protein
KNN_RS02615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KNN_RS02620	COG0822	iron-sulfur transferase activity
KNN_RS02625	COG0719	Fe-S assembly protein
KNN_RS02630	COG0737	Belongs to the 5'-nucleotidase family
KNN_RS02635	COG3377	Domain of unknown function (DUF1805)
KNN_RS02645	COG0739	heme binding
KNN_RS02670	COG4377	Putative membrane peptidase family (DUF2324)
KNN_RS02675	COG0789	Transcriptional regulator
KNN_RS02685	COG4470	Protein conserved in bacteria
KNN_RS02705	COG1494	fructose-1,6-bisphosphatase
KNN_RS02710	COG2445	Protein of unknown function DUF86
KNN_RS02720	COG0647	UMP catabolic process
KNN_RS02725	COG2249	NAD(P)H dehydrogenase (quinone) activity
KNN_RS02735	COG1358	cellular component organization or biogenesis
KNN_RS02755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KNN_RS02760	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KNN_RS02770	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KNN_RS02775	COG4837	Protein of unknown function (DUF1462)
KNN_RS02820	COG2824	Alkylphosphonate utilization operon protein PhnA
KNN_RS02825	COG0390	transport system, permease component
KNN_RS02830	COG2274	protein secretion by the type I secretion system
KNN_RS02840	COG1252	NADH dehydrogenase
KNN_RS02855	COG0316	Belongs to the HesB IscA family
KNN_RS02890	COG3620	sequence-specific DNA binding
KNN_RS02905	COG3646	Phage regulatory protein
KNN_RS02905	COG3645	SOS response
KNN_RS02930	COG1191	sigma factor activity
KNN_RS02965	COG0582	viral genome integration into host DNA
KNN_RS03000	COG5484	DNA packaging
KNN_RS03015	COG0740	serine-type endopeptidase activity
KNN_RS03080	COG4824	toxin secretion phage lysis holin
KNN_RS03085	COG5632	N-Acetylmuramoyl-L-alanine amidase
KNN_RS03085	COG3409	Peptidoglycan-binding domain 1 protein
KNN_RS03085	COG1388	LysM domain
KNN_RS03140	COG1683	Conserved Protein
KNN_RS03155	COG3708	Transcriptional regulator
KNN_RS03170	COG1252	NADH dehydrogenase
KNN_RS03185	COG3584	3D domain protein
KNN_RS03200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KNN_RS03205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KNN_RS03210	COG1268	BioY protein
KNN_RS03220	COG2050	protein possibly involved in aromatic compounds catabolism
KNN_RS03240	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KNN_RS03245	COG5018	Exonuclease
KNN_RS03265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KNN_RS03275	COG2267	carboxylic ester hydrolase activity
KNN_RS03280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNN_RS03285	COG1522	sequence-specific DNA binding
KNN_RS03290	COG0436	Aminotransferase
KNN_RS03295	COG1098	S1 RNA binding domain
KNN_RS03300	COG2155	Conserved Protein
KNN_RS03315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KNN_RS03320	COG1285	pathogenesis
KNN_RS03355	COG0544	peptidyl-prolyl cis-trans isomerase activity
KNN_RS03455	COG1404	Belongs to the peptidase S8 family
KNN_RS03475	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KNN_RS03485	COG0058	SHG alpha-glucan phosphorylase activity
KNN_RS03515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KNN_RS03520	COG1575	Belongs to the MenA family. Type 1 subfamily
KNN_RS03525	COG1169	isochorismate synthase
KNN_RS03535	COG0596	Alpha beta hydrolase
KNN_RS03540	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KNN_RS03555	COG4948	Mandelate Racemase Muconate Lactonizing
KNN_RS03575	COG3964	amidohydrolase
KNN_RS03595	COG2188	Transcriptional regulator
KNN_RS03620	COG0577	efflux transmembrane transporter activity
KNN_RS03625	COG1136	(ABC) transporter
KNN_RS03630	COG0577	efflux transmembrane transporter activity
KNN_RS03635	COG0577	efflux transmembrane transporter activity
KNN_RS03640	COG2205	protein histidine kinase activity
KNN_RS03645	COG0745	RESPONSE REGULATOR receiver
KNN_RS03650	COG0640	Transcriptional regulator
KNN_RS03655	COG5658	integral membrane protein
KNN_RS03660	COG2207	Transcriptional regulator
KNN_RS03660	COG3708	Transcriptional regulator
KNN_RS03665	COG1136	(ABC) transporter
KNN_RS03670	COG0577	efflux transmembrane transporter activity
KNN_RS03680	COG0586	Pfam SNARE associated Golgi protein
KNN_RS03720	COG1597	lipid kinase activity
KNN_RS03725	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KNN_RS03750	COG0745	RESPONSE REGULATOR receiver
KNN_RS03755	COG5002	protein histidine kinase activity
KNN_RS03785	COG1842	Phage shock protein A
KNN_RS03810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNN_RS03825	COG1294	oxidase, subunit
KNN_RS03830	COG1271	oxidase subunit
KNN_RS03835	COG0288	reversible hydration of carbon dioxide
KNN_RS03845	COG1854	S-ribosylhomocysteine lyase activity
KNN_RS03875	COG0494	nUDIX hydrolase
KNN_RS03890	COG2801	Transposase and inactivated derivatives
KNN_RS03910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNN_RS03915	COG1116	anion transmembrane transporter activity
KNN_RS03920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KNN_RS03940	COG1368	sulfuric ester hydrolase activity
KNN_RS03945	COG2267	carboxylic ester hydrolase activity
KNN_RS03965	COG3852	Histidine kinase
KNN_RS03970	COG5002	protein histidine kinase activity
KNN_RS04010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS04030	COG0438	transferase activity, transferring glycosyl groups
KNN_RS04035	COG0671	phosphoesterase, PA-phosphatase related
KNN_RS04040	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KNN_RS04045	COG2267	carboxylic ester hydrolase activity
KNN_RS04060	COG1794	racemase activity, acting on amino acids and derivatives
KNN_RS04075	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KNN_RS04080	COG1242	4 iron, 4 sulfur cluster binding
KNN_RS04100	COG1136	(ABC) transporter
KNN_RS04110	COG0582	viral genome integration into host DNA
KNN_RS04115	COG0490	domain, Protein
KNN_RS04120	COG0475	glutathione-regulated potassium exporter activity
KNN_RS04125	COG2814	Major facilitator Superfamily
KNN_RS04165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KNN_RS04175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNN_RS04195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KNN_RS04200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KNN_RS04210	COG0303	'Molybdopterin
KNN_RS04215	COG1763	Mo-molybdopterin cofactor biosynthetic process
KNN_RS04220	COG0314	molybdopterin synthase activity
KNN_RS04245	COG1329	Transcriptional regulator
KNN_RS04265	COG3832	glyoxalase III activity
KNN_RS04275	COG2814	Major facilitator Superfamily
KNN_RS04280	COG2081	HI0933 family
KNN_RS04285	COG2244	polysaccharide biosynthetic process
KNN_RS04290	COG1187	pseudouridine synthase activity
KNN_RS04295	COG1349	DNA-binding transcription factor activity
KNN_RS04300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KNN_RS04310	COG1523	belongs to the glycosyl hydrolase 13 family
KNN_RS04315	COG0510	thiamine kinase activity
KNN_RS04330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNN_RS04340	COG1363	Peptidase, m42
KNN_RS04350	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KNN_RS04355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KNN_RS04365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KNN_RS04375	COG0860	N-Acetylmuramoyl-L-alanine amidase
KNN_RS04375	COG1388	LysM domain
KNN_RS04380	COG1674	ftsk spoiiie
KNN_RS04395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS04420	COG2309	aminopeptidase activity
KNN_RS04430	COG3118	belongs to the thioredoxin family
KNN_RS04435	COG4851	CamS sex pheromone cAM373 precursor
KNN_RS04440	COG1605	Chorismate mutase
KNN_RS04440	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KNN_RS04445	COG1609	Transcriptional regulator
KNN_RS04480	COG0666	response to abiotic stimulus
KNN_RS04490	COG0745	RESPONSE REGULATOR receiver
KNN_RS04505	COG0123	including yeast histone deacetylase and acetoin utilization protein
KNN_RS04510	COG0517	IMP dehydrogenase activity
KNN_RS04515	COG0454	-acetyltransferase
KNN_RS04520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KNN_RS04525	COG0110	maltose O-acetyltransferase activity
KNN_RS04535	COG1595	DNA-templated transcription, initiation
KNN_RS04560	COG0626	cystathionine gamma-synthase activity
KNN_RS04565	COG1956	GAF domain-containing protein
KNN_RS04570	COG1309	transcriptional regulator
KNN_RS04575	COG0697	spore germination
KNN_RS04580	COG0583	DNA-binding transcription factor activity
KNN_RS04590	COG1104	cysteine desulfurase activity
KNN_RS04605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KNN_RS04615	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KNN_RS04630	COG3874	Sporulation protein YtfJ
KNN_RS04635	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KNN_RS04640	COG0827	DNA restriction-modification system
KNN_RS04665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNN_RS04705	COG0589	response to stress
KNN_RS04710	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS04725	COG0662	Cupin 2, conserved barrel domain protein
KNN_RS04730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS04760	COG0006	proline dipeptidase activity
KNN_RS04775	COG4109	DRTGG domain
KNN_RS04790	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KNN_RS04805	COG0587	DNA-directed DNA polymerase activity
KNN_RS04810	COG0281	malic enzyme
KNN_RS04815	COG1725	Transcriptional regulator
KNN_RS04840	COG3030	protein affecting phage T7 exclusion by the F plasmid
KNN_RS04845	COG0628	permease
KNN_RS04855	COG0372	Belongs to the citrate synthase family
KNN_RS04860	COG0538	isocitrate dehydrogenase activity
KNN_RS04875	COG0745	RESPONSE REGULATOR receiver
KNN_RS04880	COG5002	protein histidine kinase activity
KNN_RS04885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNN_RS04885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNN_RS04895	COG1971	Probably functions as a manganese efflux pump
KNN_RS04905	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KNN_RS04910	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KNN_RS04920	COG3611	Membrane attachment protein
KNN_RS04925	COG1484	DNA-dependent DNA replication
KNN_RS04940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KNN_RS04965	COG1363	Peptidase, m42
KNN_RS04970	COG1309	transcriptional regulator
KNN_RS04975	COG1566	PFAM secretion protein HlyD family protein
KNN_RS04980	COG2814	Major facilitator Superfamily
KNN_RS05000	COG1418	mRNA catabolic process
KNN_RS05010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNN_RS05055	COG1286	toxin biosynthetic process
KNN_RS05060	COG1796	DNA polymerase
KNN_RS05060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KNN_RS05070	COG1187	pseudouridine synthase activity
KNN_RS05075	COG1114	Component of the transport system for branched-chain amino acids
KNN_RS05080	COG5386	Cell surface protein
KNN_RS05090	COG5386	Cell surface protein
KNN_RS05105	COG1120	ATPase activity
KNN_RS05110	COG4509	Sortase family
KNN_RS05120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KNN_RS05125	COG4895	conserved protein (DUF2196)
KNN_RS05135	COG0745	RESPONSE REGULATOR receiver
KNN_RS05140	COG2205	protein histidine kinase activity
KNN_RS05145	COG1131	(ABC) transporter
KNN_RS05170	COG2318	DinB family
KNN_RS05195	COG0318	PFAM AMP-dependent synthetase and ligase
KNN_RS05200	COG1309	transcriptional regulator
KNN_RS05205	COG1024	Enoyl-CoA hydratase
KNN_RS05210	COG2086	electron transfer activity
KNN_RS05215	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KNN_RS05220	COG3118	belongs to the thioredoxin family
KNN_RS05230	COG1719	4-vinyl reductase, 4VR
KNN_RS05235	COG2009	succinate dehydrogenase
KNN_RS05240	COG1053	succinate dehydrogenase
KNN_RS05245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KNN_RS05250	COG0824	Thioesterase
KNN_RS05255	COG1876	peptidase activity
KNN_RS05260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KNN_RS05265	COG1360	Flagellar Motor Protein
KNN_RS05270	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KNN_RS05275	COG4152	abc transporter atp-binding protein
KNN_RS05280	COG1668	transmembrane transport
KNN_RS05285	COG1959	2 iron, 2 sulfur cluster binding
KNN_RS05295	COG0697	spore germination
KNN_RS05300	COG1396	sequence-specific DNA binding
KNN_RS05305	COG1983	PspC domain protein
KNN_RS05310	COG0402	S-adenosylhomocysteine deaminase activity
KNN_RS05315	COG2233	PERMEase
KNN_RS05320	COG2197	response regulator
KNN_RS05330	COG1309	transcriptional regulator
KNN_RS05350	COG5401	PFAM Sporulation and spore germination
KNN_RS05365	COG0622	Phosphoesterase
KNN_RS05405	COG1067	ATP-dependent peptidase activity
KNN_RS05405	COG0470	DNA polymerase III
KNN_RS05420	COG1764	response to oxidative stress
KNN_RS05425	COG1846	Transcriptional regulator
KNN_RS05435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KNN_RS05445	COG1587	Uroporphyrinogen-III synthase
KNN_RS05450	COG0113	porphobilinogen synthase activity
KNN_RS05460	COG1388	LysM domain
KNN_RS05475	COG0285	dihydrofolate synthase activity
KNN_RS05715	COG5632	N-Acetylmuramoyl-L-alanine amidase
KNN_RS05745	COG1077	Cell shape determining protein MreB Mrl
KNN_RS05765	COG2894	cell division
KNN_RS05770	COG0739	heme binding
KNN_RS05775	COG1994	Peptidase M50
KNN_RS05780	COG1530	ribonuclease E activity
KNN_RS05790	COG2868	ribosomal protein
KNN_RS05800	COG3290	protein histidine kinase activity
KNN_RS05810	COG0745	RESPONSE REGULATOR receiver
KNN_RS05815	COG5002	protein histidine kinase activity
KNN_RS05820	COG1136	(ABC) transporter
KNN_RS05825	COG0577	efflux transmembrane transporter activity
KNN_RS05830	COG0577	efflux transmembrane transporter activity
KNN_RS05835	COG0077	Prephenate dehydratase
KNN_RS05840	COG2258	MOSC domain
KNN_RS05845	COG1827	regulation of RNA biosynthetic process
KNN_RS05850	COG1104	cysteine desulfurase activity
KNN_RS05855	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KNN_RS05860	COG0157	Belongs to the NadC ModD family
KNN_RS05890	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KNN_RS05920	COG1862	Preprotein translocase
KNN_RS05930	COG2323	membrane
KNN_RS05935	COG2244	polysaccharide biosynthetic process
KNN_RS05945	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KNN_RS05945	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KNN_RS05950	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KNN_RS05955	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KNN_RS05955	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KNN_RS05965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KNN_RS05990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KNN_RS06000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KNN_RS06005	COG1959	2 iron, 2 sulfur cluster binding
KNN_RS06010	COG1104	cysteine desulfurase activity
KNN_RS06025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KNN_RS06045	COG0628	permease
KNN_RS06075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KNN_RS06080	COG4122	O-methyltransferase activity
KNN_RS06085	COG0826	peptidase U32
KNN_RS06090	COG0826	peptidase U32
KNN_RS06110	COG0768	penicillin binding
KNN_RS06135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KNN_RS06140	COG0626	cystathionine gamma-synthase activity
KNN_RS06145	COG1012	belongs to the aldehyde dehydrogenase family
KNN_RS06145	COG1454	alcohol dehydrogenase
KNN_RS06155	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KNN_RS06195	COG2259	Doxx family
KNN_RS06200	COG2514	catechol 2,3-dioxygenase activity
KNN_RS06210	COG3186	Phenylalanine-4-hydroxylase
KNN_RS06215	COG3547	Transposase (IS116 IS110 IS902 family)
KNN_RS06220	COG1404	Belongs to the peptidase S8 family
KNN_RS06255	COG2267	carboxylic ester hydrolase activity
KNN_RS06265	COG1785	Belongs to the alkaline phosphatase family
KNN_RS06275	COG2357	RelA SpoT domain protein
KNN_RS06280	COG0778	Nitroreductase
KNN_RS06315	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KNN_RS06320	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KNN_RS06330	COG1534	Rna-binding protein
KNN_RS06340	COG1713	HD superfamily hydrolase involved in NAD metabolism
KNN_RS06345	COG0799	negative regulation of ribosome biogenesis
KNN_RS06350	COG2226	methyltransferase
KNN_RS06355	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KNN_RS06360	COG1596	polysaccharide export
KNN_RS06360	COG1555	photosystem II stabilization
KNN_RS06365	COG2131	deaminase
KNN_RS06370	COG2333	competence protein COMEC
KNN_RS06370	COG0658	competence protein
KNN_RS06380	COG1466	dna polymerase III delta subunit
KNN_RS06405	COG1733	regulation of RNA biosynthetic process
KNN_RS06410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KNN_RS06440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KNN_RS06445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KNN_RS06450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KNN_RS06455	COG1610	YqeY-like protein
KNN_RS06475	COG1702	phosphate starvation-inducible protein PhoH
KNN_RS06480	COG1480	7TM receptor with intracellular HD hydrolase
KNN_RS06490	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KNN_RS06495	COG0295	cytidine deaminase activity
KNN_RS06500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KNN_RS06515	COG0517	IMP dehydrogenase activity
KNN_RS06525	COG0358	DNA primase activity
KNN_RS06530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KNN_RS06540	COG2384	SAM-dependent methyltransferase
KNN_RS06545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KNN_RS06575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNN_RS06580	COG1121	(ABC) transporter
KNN_RS06585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KNN_RS06590	COG0735	belongs to the Fur family
KNN_RS06605	COG5521	maltodextrose utilization protein MalA
KNN_RS06615	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KNN_RS06620	COG0477	Major facilitator Superfamily
KNN_RS06625	COG0768	penicillin binding
KNN_RS06630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KNN_RS06635	COG0573	inorganic phosphate transmembrane transporter activity
KNN_RS06640	COG0573	inorganic phosphate transmembrane transporter activity
KNN_RS06650	COG0704	Plays a role in the regulation of phosphate uptake
KNN_RS06655	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KNN_RS06665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KNN_RS06670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KNN_RS06675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KNN_RS06680	COG4483	Protein conserved in bacteria
KNN_RS06685	COG1940	carbohydrate kinase activity
KNN_RS06690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNN_RS06710	COG0626	cystathionine gamma-synthase activity
KNN_RS06715	COG0626	cystathionine gamma-synthase activity
KNN_RS06720	COG0646	methionine synthase
KNN_RS06720	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KNN_RS06725	COG0646	methionine synthase
KNN_RS06725	COG1410	methionine synthase
KNN_RS06790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KNN_RS06795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KNN_RS06860	COG0305	Participates in initiation and elongation during chromosome replication
KNN_RS06900	COG3728	DNA packaging
KNN_RS06995	COG4824	toxin secretion phage lysis holin
KNN_RS07000	COG3409	Peptidoglycan-binding domain 1 protein
KNN_RS07000	COG5632	N-Acetylmuramoyl-L-alanine amidase
KNN_RS07000	COG1388	LysM domain
KNN_RS07015	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KNN_RS07040	COG1459	type II secretion system
KNN_RS07080	COG1396	sequence-specific DNA binding
KNN_RS07100	COG1846	Transcriptional regulator
KNN_RS07105	COG1484	DNA-dependent DNA replication
KNN_RS07115	COG2002	toxin-antitoxin pair type II binding
KNN_RS07200	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KNN_RS07205	COG0582	viral genome integration into host DNA
KNN_RS07235	COG4626	Terminase
KNN_RS07235	COG1802	Transcriptional regulator
KNN_RS07245	COG0740	serine-type endopeptidase activity
KNN_RS07315	COG4824	toxin secretion phage lysis holin
KNN_RS07320	COG3409	Peptidoglycan-binding domain 1 protein
KNN_RS07320	COG5632	N-Acetylmuramoyl-L-alanine amidase
KNN_RS07320	COG1388	LysM domain
KNN_RS07330	COG2801	Transposase and inactivated derivatives
KNN_RS07410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KNN_RS07440	COG1725	Transcriptional regulator
KNN_RS07445	COG1131	(ABC) transporter
KNN_RS07475	COG2076	Multidrug Resistance protein
KNN_RS07480	COG2076	Multidrug Resistance protein
KNN_RS07490	COG1609	Transcriptional regulator
KNN_RS07500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNN_RS07535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KNN_RS07545	COG3872	metal-dependent enzyme
KNN_RS07560	COG0006	proline dipeptidase activity
KNN_RS07585	COG3854	ATPases associated with a variety of cellular activities
KNN_RS07625	COG0511	ligase activity, forming carbon-carbon bonds
KNN_RS07630	COG0439	Biotin carboxylase
KNN_RS07635	COG1302	Protein conserved in bacteria
KNN_RS07660	COG0142	geranyltranstransferase activity
KNN_RS07670	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KNN_RS07680	COG0497	DNA recombination
KNN_RS07685	COG0750	zinc metalloprotease
KNN_RS07700	COG3093	addiction module antidote protein HigA
KNN_RS07705	COG0584	glycerophosphoryl diester phosphodiesterase
KNN_RS07715	COG3290	protein histidine kinase activity
KNN_RS07715	COG3829	transcription factor binding
KNN_RS07720	COG0280	phosphate acetyltransferase
KNN_RS07735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KNN_RS07740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KNN_RS07745	COG0022	dehydrogenase e1 component
KNN_RS07750	COG0508	dehydrogenase complex catalyzes the overall conversion of
KNN_RS07755	COG0772	Belongs to the SEDS family
KNN_RS07760	COG2323	membrane
KNN_RS07780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNN_RS07785	COG0765	amino acid transport
KNN_RS07790	COG1126	abc transporter atp-binding protein
KNN_RS07795	COG4129	membrane
KNN_RS07800	COG1376	ErfK ybiS ycfS ynhG family protein
KNN_RS07810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS07815	COG2195	Cleaves the N-terminal amino acid of tripeptides
KNN_RS07825	COG1285	pathogenesis
KNN_RS07845	COG1760	l-serine dehydratase
KNN_RS07850	COG1760	l-serine dehydratase
KNN_RS07855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KNN_RS07860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNN_RS07865	COG0300	oxidoreductase activity
KNN_RS07910	COG1522	sequence-specific DNA binding
KNN_RS07920	COG0737	Belongs to the 5'-nucleotidase family
KNN_RS07925	COG1757	Na H antiporter
KNN_RS07935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KNN_RS07950	COG2226	methyltransferase
KNN_RS07950	COG1073	alpha beta
KNN_RS07980	COG0307	riboflavin synthase, alpha
KNN_RS07985	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KNN_RS07985	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KNN_RS08000	COG1073	alpha beta
KNN_RS08005	COG0456	acetyltransferase
KNN_RS08010	COG1609	Transcriptional regulator
KNN_RS08015	COG2056	Na+-H+ antiporter family
KNN_RS08020	COG0596	Alpha beta hydrolase
KNN_RS08030	COG0737	Belongs to the 5'-nucleotidase family
KNN_RS08030	COG4085	toxin activity
KNN_RS08030	COG1525	nuclease
KNN_RS08040	COG0456	acetyltransferase
KNN_RS08040	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KNN_RS08045	COG0656	L-ascorbic acid biosynthetic process
KNN_RS08050	COG0667	Aldo Keto reductase
KNN_RS08070	COG1300	Membrane
KNN_RS08075	COG0735	belongs to the Fur family
KNN_RS08085	COG4974	Belongs to the 'phage' integrase family
KNN_RS08110	COG0598	Magnesium transport protein CorA
KNN_RS08125	COG1846	Transcriptional regulator
KNN_RS08145	COG1131	(ABC) transporter
KNN_RS08150	COG1725	Transcriptional regulator
KNN_RS08155	COG1686	Belongs to the peptidase S11 family
KNN_RS08175	COG0733	neurotransmitter:sodium symporter activity
KNN_RS08200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNN_RS08215	COG0697	spore germination
KNN_RS08220	COG0561	phosphatase activity
KNN_RS08225	COG4086	secreted protein
KNN_RS08230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KNN_RS08235	COG0456	acetyltransferase
KNN_RS08240	COG1547	Domain of unknown function (DUF309)
KNN_RS08260	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KNN_RS08270	COG2188	Transcriptional regulator
KNN_RS08280	COG3711	transcriptional antiterminator
KNN_RS08285	COG2190	(PTS) system
KNN_RS08285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KNN_RS08285	COG1263	PTS System
KNN_RS08310	COG0778	Nitroreductase
KNN_RS08315	COG2199	diguanylate cyclase activity
KNN_RS08325	COG2084	Dehydrogenase
KNN_RS08360	COG0436	Aminotransferase
KNN_RS08365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KNN_RS08385	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS08390	COG1695	Transcriptional regulator
KNN_RS08415	COG2801	Transposase and inactivated derivatives
KNN_RS08430	COG0183	Belongs to the thiolase family
KNN_RS08475	COG3842	ATPase activity
KNN_RS08480	COG0366	Alpha amylase catalytic
KNN_RS08490	COG2182	Extracellular solute-binding protein
KNN_RS08495	COG1175	transmembrane transport
KNN_RS08500	COG3833	ABC-type maltose transport systems, permease component
KNN_RS08505	COG1609	Transcriptional regulator
KNN_RS08510	COG0436	Aminotransferase
KNN_RS08520	COG2205	protein histidine kinase activity
KNN_RS08530	COG3209	COG3209 Rhs family protein
KNN_RS08550	COG2814	Major facilitator Superfamily
KNN_RS08595	COG1408	metallophosphoesterase
KNN_RS08600	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS08605	COG2200	EAL domain
KNN_RS08620	COG4703	Protein of unknown function (DUF1797)
KNN_RS08630	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KNN_RS08640	COG0517	IMP dehydrogenase activity
KNN_RS08645	COG0583	DNA-binding transcription factor activity
KNN_RS08665	COG0569	domain protein
KNN_RS08670	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNN_RS08680	COG0561	phosphatase activity
KNN_RS08695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KNN_RS08700	COG0022	dehydrogenase e1 component
KNN_RS08750	COG1982	Orn Lys Arg decarboxylase major
KNN_RS08770	COG0483	inositol monophosphate 1-phosphatase activity
KNN_RS08780	COG1217	gtp-binding protein TYPA
KNN_RS08795	COG4896	Protein conserved in bacteria
KNN_RS08805	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KNN_RS08810	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KNN_RS08820	COG0772	Belongs to the SEDS family
KNN_RS08825	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KNN_RS08830	COG2801	Transposase and inactivated derivatives
KNN_RS08875	COG3336	cytochrome c oxidase
KNN_RS08890	COG2340	Cysteine-rich secretory protein family
KNN_RS08905	COG0406	alpha-ribazole phosphatase activity
KNN_RS08910	COG3679	Belongs to the UPF0342 family
KNN_RS08925	COG0742	ribosomal rna small subunit methyltransferase
KNN_RS08935	COG3314	Sporulation integral membrane protein YlbJ
KNN_RS08940	COG1752	Esterase of the alpha-beta hydrolase superfamily
KNN_RS08945	COG3480	Lon protease (S16) C-terminal proteolytic domain
KNN_RS08955	COG1399	metal-binding, possibly nucleic acid-binding protein
KNN_RS08960	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KNN_RS08975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KNN_RS08995	COG0768	penicillin binding
KNN_RS09000	COG0768	penicillin binding
KNN_RS09020	COG0772	Belongs to the SEDS family
KNN_RS09040	COG0849	cell division
KNN_RS09045	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KNN_RS09055	COG1191	sigma factor activity
KNN_RS09060	COG1191	sigma factor activity
KNN_RS09065	COG1873	PFAM PRC-barrel domain
KNN_RS09075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KNN_RS09085	COG0762	integral membrane protein
KNN_RS09090	COG2302	S4 RNA-binding domain
KNN_RS09095	COG3599	regulation of cell shape
KNN_RS09115	COG0564	pseudouridine synthase activity
KNN_RS09175	COG3069	C4-dicarboxylate transmembrane transporter activity
KNN_RS09195	COG0006	proline dipeptidase activity
KNN_RS09205	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KNN_RS09210	COG1561	YicC-like family, N-terminal region
KNN_RS09230	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KNN_RS09235	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KNN_RS09250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KNN_RS09250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KNN_RS09260	COG0631	protein serine/threonine phosphatase activity
KNN_RS09265	COG0515	serine threonine protein kinase
KNN_RS09265	COG2815	serine threonine protein kinase
KNN_RS09275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KNN_RS09280	COG1564	THIamine pyrophosphokinase
KNN_RS09295	COG1302	Protein conserved in bacteria
KNN_RS09300	COG1461	Dihydroxyacetone kinase
KNN_RS09305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KNN_RS09320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KNN_RS09325	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS09330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNN_RS09340	COG1196	nuclear chromosome segregation
KNN_RS09345	COG0552	protein localization to endoplasmic reticulum
KNN_RS09355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KNN_RS09365	COG1837	Belongs to the UPF0109 family
KNN_RS09405	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KNN_RS09410	COG0758	DNA mediated transformation
KNN_RS09415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KNN_RS09425	COG4974	Belongs to the 'phage' integrase family
KNN_RS09470	COG4589	Belongs to the CDS family
KNN_RS09480	COG0750	zinc metalloprotease
KNN_RS09500	COG0195	Participates in both transcription termination and antitermination
KNN_RS09505	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KNN_RS09510	COG1358	cellular component organization or biogenesis
KNN_RS09520	COG1550	Protein conserved in bacteria
KNN_RS09525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KNN_RS09535	COG0196	riboflavin kinase activity
KNN_RS09550	COG0726	polysaccharide deacetylase
KNN_RS09555	COG0612	Peptidase, M16
KNN_RS09560	COG1873	PFAM PRC-barrel domain
KNN_RS09565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNN_RS09570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KNN_RS09575	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KNN_RS09580	COG0527	aspartate kinase activity
KNN_RS09590	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNN_RS09595	COG0740	serine-type endopeptidase activity
KNN_RS09610	COG2188	Transcriptional regulator
KNN_RS09615	COG1744	ABC transporter substrate-binding protein PnrA-like
KNN_RS09620	COG3845	ABC transporter
KNN_RS09625	COG4603	Belongs to the binding-protein-dependent transport system permease family
KNN_RS09630	COG1079	Belongs to the binding-protein-dependent transport system permease family
KNN_RS09635	COG0612	Peptidase, M16
KNN_RS09640	COG0612	Peptidase, M16
KNN_RS09645	COG0300	oxidoreductase activity
KNN_RS09660	COG1426	Protein conserved in bacteria
KNN_RS09665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KNN_RS09685	COG1692	metallophosphoesterase
KNN_RS09690	COG2359	stage V sporulation protein S
KNN_RS09700	COG0674	pyruvate-flavodoxin oxidoreductase activity
KNN_RS09700	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KNN_RS09705	COG1013	pyruvate-flavodoxin oxidoreductase activity
KNN_RS09715	COG4550	Control of competence regulator ComK, YlbF/YmcA
KNN_RS09760	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KNN_RS09765	COG1368	sulfuric ester hydrolase activity
KNN_RS09775	COG3773	Cell wall hydrolase
KNN_RS09780	COG1404	Belongs to the peptidase S8 family
KNN_RS09790	COG2723	6-phospho-beta-galactosidase activity
KNN_RS09795	COG2188	Transcriptional regulator
KNN_RS09805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNN_RS09815	COG1346	cytolysis
KNN_RS09830	COG1086	Polysaccharide biosynthesis protein
KNN_RS09850	COG5001	Diguanylate cyclase
KNN_RS09850	COG3300	MHYT domain
KNN_RS09855	COG2267	carboxylic ester hydrolase activity
KNN_RS09875	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KNN_RS09880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KNN_RS09885	COG2169	Transcriptional regulator
KNN_RS09890	COG0708	Exodeoxyribonuclease III
KNN_RS09910	COG3344	reverse transcriptase
KNN_RS09930	COG3344	reverse transcriptase
KNN_RS09940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNN_RS09945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNN_RS09950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNN_RS09955	COG1120	ATPase activity
KNN_RS09960	COG2819	hydrolase of the alpha beta superfamily
KNN_RS09970	COG1937	Protein conserved in bacteria
KNN_RS09975	COG2608	mercury ion transmembrane transporter activity
KNN_RS09980	COG2217	Heavy metal translocating P-type atpase
KNN_RS09995	COG2116	formate transmembrane transporter activity
KNN_RS10000	COG1408	metallophosphoesterase
KNN_RS10010	COG1113	amino acid transport
KNN_RS10025	COG2322	membrane
KNN_RS10035	COG1979	alcohol dehydrogenase
KNN_RS10040	COG1349	DNA-binding transcription factor activity
KNN_RS10045	COG1105	Belongs to the carbohydrate kinase PfkB family
KNN_RS10050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KNN_RS10050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KNN_RS10050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KNN_RS10055	COG1388	LysM domain
KNN_RS10055	COG3584	3D domain protein
KNN_RS10080	COG2801	Transposase and inactivated derivatives
KNN_RS10095	COG0464	growth
KNN_RS10105	COG2860	membrane
KNN_RS10110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KNN_RS10115	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KNN_RS10120	COG0789	Transcriptional regulator
KNN_RS10125	COG0174	glutamine synthetase
KNN_RS10130	COG0582	viral genome integration into host DNA
KNN_RS10265	COG0582	viral genome integration into host DNA
KNN_RS10365	COG4824	toxin secretion phage lysis holin
KNN_RS10375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KNN_RS10405	COG0741	lytic transglycosylase activity
KNN_RS10410	COG0739	heme binding
KNN_RS10425	COG1388	LysM domain
KNN_RS10425	COG5632	N-Acetylmuramoyl-L-alanine amidase
KNN_RS10425	COG3409	Peptidoglycan-binding domain 1 protein
KNN_RS10435	COG1695	Transcriptional regulator
KNN_RS10455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KNN_RS10465	COG0737	Belongs to the 5'-nucleotidase family
KNN_RS10475	COG0737	Belongs to the 5'-nucleotidase family
KNN_RS10480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNN_RS10490	COG3639	organic phosphonate transmembrane transporter activity
KNN_RS10515	COG1132	(ABC) transporter
KNN_RS10520	COG1132	(ABC) transporter
KNN_RS10545	COG0730	response to heat
KNN_RS10560	COG1346	cytolysis
KNN_RS10570	COG0583	DNA-binding transcription factor activity
KNN_RS10585	COG1131	(ABC) transporter
KNN_RS10595	COG1473	amidohydrolase
KNN_RS10605	COG0785	Cytochrome C biogenesis protein
KNN_RS10610	COG4846	Membrane protein involved in cytochrome C biogenesis
KNN_RS10660	COG0010	Belongs to the arginase family
KNN_RS10665	COG1329	Transcriptional regulator
KNN_RS10670	COG1902	pentaerythritol trinitrate reductase activity
KNN_RS10675	COG0069	glutamate synthase activity
KNN_RS10680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNN_RS10685	COG0346	lactoylglutathione lyase activity
KNN_RS10690	COG0400	carboxylic ester hydrolase activity
KNN_RS10695	COG5002	protein histidine kinase activity
KNN_RS10705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNN_RS10755	COG0318	PFAM AMP-dependent synthetase and ligase
KNN_RS10760	COG1268	BioY protein
KNN_RS10765	COG0318	PFAM AMP-dependent synthetase and ligase
KNN_RS10770	COG0183	Belongs to the thiolase family
KNN_RS10785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KNN_RS10795	COG2211	Major facilitator Superfamily
KNN_RS10825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KNN_RS10830	COG1132	(ABC) transporter
KNN_RS10845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KNN_RS10875	COG0824	Thioesterase
KNN_RS10880	COG4841	protein insertion into membrane
KNN_RS10900	COG0745	RESPONSE REGULATOR receiver
KNN_RS10905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNN_RS10910	COG1832	CoA-binding protein
KNN_RS10915	COG0187	DNA topoisomerase II activity
KNN_RS10920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNN_RS10925	COG0673	inositol 2-dehydrogenase activity
KNN_RS10945	COG1131	(ABC) transporter
KNN_RS10965	COG1595	DNA-templated transcription, initiation
KNN_RS10975	COG1316	TRANSCRIPTIONal
KNN_RS10980	COG1301	dicarboxylic acid transport
KNN_RS10985	COG4166	transmembrane transport
KNN_RS10990	COG4166	transmembrane transport
KNN_RS10995	COG4166	transmembrane transport
KNN_RS11000	COG2226	methyltransferase
KNN_RS11035	COG0531	amino acid
KNN_RS11050	COG0697	spore germination
KNN_RS11055	COG3383	formate dehydrogenase (NAD+) activity
KNN_RS11140	COG0582	viral genome integration into host DNA
KNN_RS11200	COG1802	Transcriptional regulator
KNN_RS11200	COG4626	Terminase
KNN_RS11210	COG0740	serine-type endopeptidase activity
KNN_RS11270	COG4824	toxin secretion phage lysis holin
KNN_RS11275	COG5632	N-Acetylmuramoyl-L-alanine amidase
KNN_RS11275	COG3409	Peptidoglycan-binding domain 1 protein
KNN_RS11275	COG1388	LysM domain
KNN_RS11315	COG3383	formate dehydrogenase (NAD+) activity
KNN_RS11320	COG2427	Protein of unknown function (DUF1641)
KNN_RS11325	COG5609	conserved protein (DUF2294)
KNN_RS11330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KNN_RS11340	COG2116	formate transmembrane transporter activity
KNN_RS11345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KNN_RS11350	COG0303	'Molybdopterin
KNN_RS11355	COG0314	molybdopterin synthase activity
KNN_RS11365	COG0489	protein tyrosine kinase activity
KNN_RS11380	COG3326	Membrane
KNN_RS11385	COG2962	Rard protein
KNN_RS11390	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KNN_RS11395	COG1657	PFAM Prenyltransferase squalene oxidase
KNN_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS11410	COG1012	belongs to the aldehyde dehydrogenase family
KNN_RS11420	COG4145	pantothenate transmembrane transporter activity
KNN_RS11435	COG0165	Argininosuccinate lyase
KNN_RS11445	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS11465	COG1051	belongs to the nudix hydrolase family
KNN_RS11475	COG0716	FMN binding
KNN_RS11510	COG2720	vancomycin resistance protein
KNN_RS11515	COG2801	Transposase and inactivated derivatives
KNN_RS11520	COG2963	transposase activity
KNN_RS11525	COG2514	catechol 2,3-dioxygenase activity
KNN_RS11535	COG1285	pathogenesis
KNN_RS11545	COG3852	Histidine kinase
KNN_RS11580	COG1309	transcriptional regulator
KNN_RS11590	COG2801	Transposase and inactivated derivatives
KNN_RS11620	COG0457	Tetratricopeptide repeat
KNN_RS11630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KNN_RS11640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KNN_RS11660	COG1252	NADH dehydrogenase
KNN_RS11665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNN_RS11665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNN_RS11675	COG1183	phosphatidylcholine synthase activity
KNN_RS11700	COG0277	FAD linked oxidase domain protein
KNN_RS11710	COG0457	Tetratricopeptide repeat
KNN_RS11720	COG0604	alcohol dehydrogenase
KNN_RS11725	COG0640	Transcriptional regulator
KNN_RS11735	COG0584	glycerophosphoryl diester phosphodiesterase
KNN_RS11760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KNN_RS11775	COG3781	membrane
KNN_RS11800	COG1164	Oligoendopeptidase f
KNN_RS11805	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KNN_RS11820	COG1193	negative regulation of DNA recombination
KNN_RS11840	COG0583	DNA-binding transcription factor activity
KNN_RS11855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS11875	COG3739	integral membrane protein
KNN_RS11880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNN_RS11885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNN_RS11890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNN_RS11905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KNN_RS11910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KNN_RS11940	COG2814	Major facilitator Superfamily
KNN_RS11945	COG1113	amino acid transport
KNN_RS11985	COG2801	Transposase and inactivated derivatives
KNN_RS11995	COG2072	flavoprotein involved in K transport
KNN_RS12025	COG1151	hydroxylamine reductase activity
KNN_RS12085	COG1280	lysine exporter protein (LysE YggA)
KNN_RS12095	COG1191	sigma factor activity
KNN_RS12105	COG0726	polysaccharide deacetylase
KNN_RS12115	COG1733	regulation of RNA biosynthetic process
KNN_RS12120	COG2249	NAD(P)H dehydrogenase (quinone) activity
KNN_RS12125	COG0318	PFAM AMP-dependent synthetase and ligase
KNN_RS12130	COG0384	phenazine biosynthesis protein PhzF
KNN_RS12150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNN_RS12175	COG1733	regulation of RNA biosynthetic process
KNN_RS12180	COG1733	regulation of RNA biosynthetic process
KNN_RS12185	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KNN_RS12190	COG0673	inositol 2-dehydrogenase activity
KNN_RS12195	COG2188	Transcriptional regulator
KNN_RS12200	COG1733	regulation of RNA biosynthetic process
KNN_RS12230	COG0814	amino acid
KNN_RS12245	COG0659	secondary active sulfate transmembrane transporter activity
KNN_RS12250	COG2824	Alkylphosphonate utilization operon protein PhnA
KNN_RS12270	COG2814	Major facilitator Superfamily
KNN_RS12275	COG0656	L-ascorbic acid biosynthetic process
KNN_RS12290	COG1733	regulation of RNA biosynthetic process
KNN_RS12295	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KNN_RS12295	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KNN_RS12300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KNN_RS12300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KNN_RS12310	COG0840	transmembrane signaling receptor activity
KNN_RS12325	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS12330	COG3321	synthase
KNN_RS12330	COG0604	alcohol dehydrogenase
KNN_RS12335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNN_RS12340	COG0604	alcohol dehydrogenase
KNN_RS12350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KNN_RS12355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KNN_RS12360	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KNN_RS12375	COG1070	Carbohydrate kinase
KNN_RS12380	COG2706	6-phosphogluconolactonase activity
KNN_RS12385	COG3813	Protein conserved in bacteria
KNN_RS12390	COG1357	PFAM Pentapeptide repeats (8 copies)
KNN_RS12400	COG0697	spore germination
KNN_RS12430	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KNN_RS12440	COG0789	Transcriptional regulator
KNN_RS12445	COG1253	flavin adenine dinucleotide binding
KNN_RS12495	COG0628	permease
KNN_RS12540	COG1011	Hydrolase
KNN_RS12565	COG1131	(ABC) transporter
KNN_RS12575	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS12595	COG0469	pyruvate kinase activity
KNN_RS12605	COG0778	Nitroreductase
KNN_RS12610	COG1733	regulation of RNA biosynthetic process
KNN_RS12650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KNN_RS12655	COG3547	Transposase (IS116 IS110 IS902 family)
KNN_RS12675	COG2356	endonuclease I
KNN_RS12680	COG1288	antiporter activity
KNN_RS12705	COG3344	reverse transcriptase
KNN_RS12760	COG2249	NAD(P)H dehydrogenase (quinone) activity
KNN_RS12770	COG2031	fatty acid transporter
KNN_RS12780	COG2814	Major facilitator Superfamily
KNN_RS12785	COG1846	Transcriptional regulator
KNN_RS12800	COG0477	Major facilitator Superfamily
KNN_RS12810	COG2843	Capsule synthesis protein
KNN_RS12815	COG1876	peptidase activity
KNN_RS12920	COG3409	Peptidoglycan-binding domain 1 protein
KNN_RS12920	COG5632	N-Acetylmuramoyl-L-alanine amidase
KNN_RS12940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNN_RS12940	COG2207	Transcriptional regulator
KNN_RS12945	COG0662	Cupin 2, conserved barrel domain protein
KNN_RS12965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KNN_RS12995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNN_RS13000	COG2808	Putative FMN-binding domain
KNN_RS13005	COG0456	acetyltransferase
KNN_RS13010	COG1846	Transcriptional regulator
KNN_RS13015	COG2364	Membrane
KNN_RS13025	COG3850	Histidine kinase
KNN_RS13025	COG5002	protein histidine kinase activity
KNN_RS13045	COG0577	efflux transmembrane transporter activity
KNN_RS13065	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KNN_RS13075	COG1690	Belongs to the RtcB family
KNN_RS13085	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KNN_RS13095	COG2814	Major facilitator Superfamily
KNN_RS13130	COG1136	(ABC) transporter
KNN_RS13180	COG3850	Histidine kinase
KNN_RS13180	COG5002	protein histidine kinase activity
KNN_RS13185	COG0745	RESPONSE REGULATOR receiver
KNN_RS13210	COG3547	Transposase (IS116 IS110 IS902 family)
KNN_RS13235	COG0697	spore germination
KNN_RS13240	COG0583	DNA-binding transcription factor activity
KNN_RS13245	COG0814	amino acid
KNN_RS13265	COG1309	transcriptional regulator
KNN_RS13330	COG0346	lactoylglutathione lyase activity
KNN_RS13345	COG1522	sequence-specific DNA binding
KNN_RS13350	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS13360	COG3320	Male sterility
KNN_RS13360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNN_RS13365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KNN_RS13375	COG0640	Transcriptional regulator
KNN_RS13380	COG0346	lactoylglutathione lyase activity
KNN_RS13385	COG0798	PFAM Bile acid sodium symporter
KNN_RS13395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS13410	COG1575	Belongs to the MenA family. Type 1 subfamily
KNN_RS13415	COG0456	acetyltransferase
KNN_RS13425	COG0697	spore germination
KNN_RS13440	COG5609	conserved protein (DUF2294)
KNN_RS13445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KNN_RS13455	COG0288	reversible hydration of carbon dioxide
KNN_RS13470	COG0415	Belongs to the DNA photolyase family
KNN_RS13490	COG1073	alpha beta
KNN_RS13510	COG0598	Magnesium transport protein CorA
KNN_RS13515	COG1846	Transcriptional regulator
KNN_RS13520	COG0583	DNA-binding transcription factor activity
KNN_RS13540	COG1335	isochorismatase
KNN_RS13545	COG2267	carboxylic ester hydrolase activity
KNN_RS13550	COG0737	Belongs to the 5'-nucleotidase family
KNN_RS13575	COG1115	amino acid carrier protein
KNN_RS13580	COG2066	Belongs to the glutaminase family
KNN_RS13585	COG4191	Histidine kinase
KNN_RS13590	COG0784	Response regulator, receiver
KNN_RS13605	COG0697	spore germination
KNN_RS13610	COG0531	amino acid
KNN_RS13620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KNN_RS13625	COG0531	amino acid
KNN_RS13630	COG0322	excinuclease ABC activity
KNN_RS13645	COG2207	Transcriptional regulator
KNN_RS13670	COG5002	protein histidine kinase activity
KNN_RS13690	COG1396	sequence-specific DNA binding
KNN_RS13695	COG0252	asparaginase activity
KNN_RS13700	COG1027	Aspartate ammonia-lyase
KNN_RS13710	COG1063	alcohol dehydrogenase
KNN_RS13735	COG1113	amino acid transport
KNN_RS13740	COG1280	lysine exporter protein (LysE YggA)
KNN_RS13750	COG5577	PFAM Coat F domain
KNN_RS13760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNN_RS13790	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KNN_RS13810	COG3314	Sporulation integral membrane protein YlbJ
KNN_RS13825	COG1960	acyl-CoA dehydrogenase activity
KNN_RS13835	COG0640	Transcriptional regulator
KNN_RS13840	COG3142	Participates in the control of copper homeostasis
KNN_RS13850	COG1414	Transcriptional regulator
KNN_RS13855	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KNN_RS13860	COG1984	allophanate hydrolase subunit 2
KNN_RS13890	COG0768	penicillin binding
KNN_RS13920	COG4335	DNA alkylation repair
KNN_RS13930	COG0833	amino acid
KNN_RS13940	COG0730	response to heat
KNN_RS13980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNN_RS14000	COG0456	acetyltransferase
KNN_RS14045	COG2801	Transposase and inactivated derivatives
KNN_RS14055	COG2814	Major facilitator Superfamily
KNN_RS14060	COG2508	Transcriptional regulator
KNN_RS14070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KNN_RS14085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KNN_RS14090	COG1447	Phosphotransferase system cellobiose-specific component IIA
KNN_RS14095	COG2723	6-phospho-beta-galactosidase activity
KNN_RS14100	COG1250	3-hydroxyacyl-CoA dehydrogenase
KNN_RS14105	COG1024	Enoyl-CoA hydratase
KNN_RS14110	COG0183	Belongs to the thiolase family
KNN_RS14115	COG0318	PFAM AMP-dependent synthetase and ligase
KNN_RS14125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KNN_RS14135	COG0179	Fumarylacetoacetate (FAA) hydrolase
KNN_RS14155	COG1846	Transcriptional regulator
KNN_RS14160	COG0778	Nitroreductase
KNN_RS14225	COG3344	reverse transcriptase
KNN_RS14240	COG0714	Associated with various cellular activities
KNN_RS14280	COG0753	catalase activity
KNN_RS14285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KNN_RS14320	COG0463	Glycosyl transferase, family 2
KNN_RS14365	COG0714	Associated with various cellular activities
KNN_RS14390	COG0346	lactoylglutathione lyase activity
KNN_RS14395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS14415	COG3655	Transcriptional regulator
KNN_RS14430	COG2720	vancomycin resistance protein
KNN_RS14440	COG3239	Fatty acid desaturase
KNN_RS14460	COG0833	amino acid
KNN_RS14465	COG1414	Transcriptional regulator
KNN_RS14470	COG4187	Peptidase family M20/M25/M40
KNN_RS14475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KNN_RS14490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KNN_RS14510	COG2329	Antibiotic biosynthesis monooxygenase
KNN_RS14530	COG1070	Carbohydrate kinase
KNN_RS14535	COG2390	Transcriptional regulator
KNN_RS14545	COG1172	Belongs to the binding-protein-dependent transport system permease family
KNN_RS14550	COG1172	Belongs to the binding-protein-dependent transport system permease family
KNN_RS14555	COG1879	ABC-type sugar transport system periplasmic component
KNN_RS14585	COG0346	lactoylglutathione lyase activity
KNN_RS14595	COG3584	3D domain protein
KNN_RS14595	COG1388	LysM domain
KNN_RS14640	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KNN_RS14640	COG1605	Chorismate mutase
KNN_RS14655	COG0287	Prephenate dehydrogenase
KNN_RS14670	COG1309	transcriptional regulator
KNN_RS14675	COG1033	growth of symbiont in host cell
KNN_RS14675	COG2409	Drug exporters of the RND superfamily
KNN_RS14700	COG3344	reverse transcriptase
KNN_RS14715	COG1033	growth of symbiont in host cell
KNN_RS14715	COG2409	Drug exporters of the RND superfamily
KNN_RS14730	COG1033	growth of symbiont in host cell
KNN_RS14730	COG2409	Drug exporters of the RND superfamily
KNN_RS14735	COG0488	(ABC) transporter
KNN_RS14740	COG1368	sulfuric ester hydrolase activity
KNN_RS14745	COG0861	Integral membrane protein TerC family
KNN_RS14760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNN_RS14765	COG0346	lactoylglutathione lyase activity
KNN_RS14770	COG4912	Dna alkylation repair
KNN_RS14790	COG0697	spore germination
KNN_RS14800	COG2746	aminoglycoside 3-N-acetyltransferase activity
KNN_RS14840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KNN_RS14845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNN_RS14850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNN_RS14860	COG0628	permease
KNN_RS14910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KNN_RS14915	COG0436	Aminotransferase
KNN_RS14950	COG2226	methyltransferase
KNN_RS14965	COG2261	transglycosylase associated protein
KNN_RS14985	COG0477	Major facilitator Superfamily
KNN_RS14985	COG2814	Major facilitator Superfamily
KNN_RS14990	COG4533	DNA binding
KNN_RS14995	COG0789	Transcriptional regulator
KNN_RS15000	COG1664	Polymer-forming cytoskeletal
KNN_RS15010	COG2814	Major facilitator Superfamily
KNN_RS15050	COG1307	EDD domain protein, DegV family
KNN_RS15055	COG1164	Oligoendopeptidase f
KNN_RS15095	COG0745	RESPONSE REGULATOR receiver
KNN_RS15100	COG3850	Histidine kinase
KNN_RS15100	COG5002	protein histidine kinase activity
KNN_RS15145	COG0667	Aldo Keto reductase
KNN_RS15160	COG4948	Mandelate Racemase Muconate Lactonizing
KNN_RS15170	COG4166	transmembrane transport
KNN_RS15180	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KNN_RS15190	COG0586	Pfam SNARE associated Golgi protein
KNN_RS15195	COG1078	dGTPase activity
KNN_RS15235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KNN_RS15240	COG3938	Belongs to the proline racemase family
KNN_RS15250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KNN_RS15255	COG1012	belongs to the aldehyde dehydrogenase family
KNN_RS15260	COG1115	amino acid carrier protein
KNN_RS15265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KNN_RS15280	COG3397	chitin binding
KNN_RS15295	COG4637	Psort location Cytoplasmic, score
KNN_RS15315	COG2801	Transposase and inactivated derivatives
KNN_RS15335	COG0514	ATP-dependent DNA helicase (RecQ)
KNN_RS15350	COG3973	AAA domain
KNN_RS15355	COG0456	acetyltransferase
KNN_RS15400	COG2315	Protein conserved in bacteria
KNN_RS15405	COG2226	methyltransferase
KNN_RS15410	COG2205	protein histidine kinase activity
KNN_RS15420	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KNN_RS15430	COG1819	glycosyl
KNN_RS15435	COG3397	chitin binding
KNN_RS15440	COG2153	protein acetylation
KNN_RS15470	COG4175	Glycine betaine
KNN_RS15470	COG0517	IMP dehydrogenase activity
KNN_RS15475	COG4176	ABC-type proline glycine betaine transport system permease component
KNN_RS15505	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KNN_RS15505	COG0456	acetyltransferase
KNN_RS15510	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS15520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KNN_RS15525	COG0022	dehydrogenase e1 component
KNN_RS15530	COG0508	dehydrogenase complex catalyzes the overall conversion of
KNN_RS15535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KNN_RS15550	COG1959	2 iron, 2 sulfur cluster binding
KNN_RS15565	COG1349	DNA-binding transcription factor activity
KNN_RS15580	COG3284	Transcriptional regulator
KNN_RS15615	COG1309	transcriptional regulator
KNN_RS15655	COG2959	enzyme of heme biosynthesis
KNN_RS15670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS15700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KNN_RS15710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNN_RS15715	COG0697	spore germination
KNN_RS15720	COG0201	protein transport
KNN_RS15735	COG0737	Belongs to the 5'-nucleotidase family
KNN_RS15740	COG3227	Zinc metalloprotease (Elastase)
KNN_RS15745	COG1523	belongs to the glycosyl hydrolase 13 family
KNN_RS15750	COG1073	alpha beta
KNN_RS15755	COG0577	efflux transmembrane transporter activity
KNN_RS15760	COG1136	(ABC) transporter
KNN_RS15775	COG5002	protein histidine kinase activity
KNN_RS15780	COG0745	RESPONSE REGULATOR receiver
KNN_RS15785	COG1011	Hydrolase
KNN_RS15815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KNN_RS15870	COG0322	excinuclease ABC activity
KNN_RS15910	COG4667	esterase of the alpha-beta hydrolase superfamily
KNN_RS15935	COG3878	Protein conserved in bacteria
KNN_RS15940	COG0251	oxidation-reduction process
KNN_RS15960	COG0592	DNA-directed DNA polymerase activity
KNN_RS15980	COG2223	nitrite transmembrane transporter activity
KNN_RS15990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KNN_RS16070	COG0768	penicillin binding
KNN_RS16075	COG0671	phosphoesterase, PA-phosphatase related
KNN_RS16080	COG0604	alcohol dehydrogenase
KNN_RS16140	COG2205	protein histidine kinase activity
KNN_RS16160	COG1794	racemase activity, acting on amino acids and derivatives
KNN_RS16165	COG1819	glycosyl
KNN_RS16175	COG0768	penicillin binding
KNN_RS16180	COG5002	protein histidine kinase activity
KNN_RS16185	COG0561	phosphatase activity
KNN_RS16220	COG2124	cytochrome p450
KNN_RS16275	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KNN_RS16285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNN_RS16290	COG0460	homoserine dehydrogenase
KNN_RS16310	COG0577	efflux transmembrane transporter activity
KNN_RS16315	COG1136	(ABC) transporter
KNN_RS16335	COG0488	(ABC) transporter
KNN_RS16345	COG2205	protein histidine kinase activity
KNN_RS16350	COG0745	RESPONSE REGULATOR receiver
KNN_RS16360	COG3773	Cell wall hydrolase
KNN_RS16365	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
KNN_RS16370	COG3386	PFAM SMP-30 Gluconolaconase
KNN_RS16380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KNN_RS16385	COG2323	membrane
KNN_RS16395	COG1063	alcohol dehydrogenase
KNN_RS16410	COG2368	4-hydroxyphenylacetate
KNN_RS16415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNN_RS16460	COG1733	regulation of RNA biosynthetic process
KNN_RS16475	COG3344	reverse transcriptase
KNN_RS16495	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS16500	COG0789	Transcriptional regulator
KNN_RS16500	COG4978	Transcriptional regulator
KNN_RS16505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KNN_RS16535	COG2207	Transcriptional regulator
KNN_RS16540	COG3227	Zinc metalloprotease (Elastase)
KNN_RS16555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KNN_RS16580	COG1686	Belongs to the peptidase S11 family
KNN_RS16590	COG2801	Transposase and inactivated derivatives
KNN_RS16605	COG0572	uridine kinase
KNN_RS16620	COG3547	Transposase (IS116 IS110 IS902 family)
KNN_RS16630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KNN_RS16635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KNN_RS16640	COG1024	Enoyl-CoA hydratase
KNN_RS16645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KNN_RS16650	COG0511	ligase activity, forming carbon-carbon bonds
KNN_RS16655	COG0439	Biotin carboxylase
KNN_RS16660	COG1960	acyl-CoA dehydrogenase activity
KNN_RS16675	COG1309	transcriptional regulator
KNN_RS16685	COG1131	(ABC) transporter
KNN_RS16695	COG1408	metallophosphoesterase
KNN_RS16705	COG0768	penicillin binding
KNN_RS16710	COG0768	penicillin binding
KNN_RS16720	COG1595	DNA-templated transcription, initiation
KNN_RS16730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KNN_RS16770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS16795	COG0741	lytic transglycosylase activity
KNN_RS16800	COG2312	Erythromycin esterase
KNN_RS16830	COG2814	Major facilitator Superfamily
KNN_RS16845	COG1686	Belongs to the peptidase S11 family
KNN_RS16850	COG0110	maltose O-acetyltransferase activity
KNN_RS16855	COG0730	response to heat
KNN_RS16865	COG2002	toxin-antitoxin pair type II binding
KNN_RS16895	COG2195	Cleaves the N-terminal amino acid of tripeptides
KNN_RS16925	COG1846	Transcriptional regulator
KNN_RS16935	COG2226	methyltransferase
KNN_RS16945	COG3615	Tellurite resistance protein tehB
KNN_RS16945	COG0500	methyltransferase
KNN_RS16990	COG0582	viral genome integration into host DNA
KNN_RS17040	COG1309	transcriptional regulator
KNN_RS17060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNN_RS17080	COG1846	Transcriptional regulator
KNN_RS17090	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KNN_RS17100	COG2971	BadF BadG BcrA BcrD
KNN_RS17150	COG1595	DNA-templated transcription, initiation
KNN_RS17155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KNN_RS17185	COG1396	sequence-specific DNA binding
KNN_RS17215	COG1132	(ABC) transporter
KNN_RS17220	COG1132	(ABC) transporter
KNN_RS17235	COG2258	MOSC domain
KNN_RS17240	COG0583	DNA-binding transcription factor activity
KNN_RS17260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KNN_RS17265	COG0583	DNA-binding transcription factor activity
KNN_RS17295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS17305	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KNN_RS17330	COG1247	-acetyltransferase
KNN_RS17375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNN_RS17390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KNN_RS17420	COG1234	tRNA 3'-trailer cleavage
KNN_RS17430	COG0028	Belongs to the TPP enzyme family
KNN_RS17450	COG2814	Major facilitator Superfamily
KNN_RS17460	COG1136	(ABC) transporter
KNN_RS17465	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KNN_RS17470	COG1187	pseudouridine synthase activity
KNN_RS17490	COG1115	amino acid carrier protein
KNN_RS17525	COG3344	reverse transcriptase
KNN_RS17550	COG2318	DinB family
KNN_RS17560	COG0776	regulation of translation
KNN_RS17575	COG2814	Major facilitator Superfamily
KNN_RS17580	COG3251	PFAM MbtH domain protein
KNN_RS17585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KNN_RS17590	COG3433	isochorismatase activity
KNN_RS17590	COG1535	isochorismatase
KNN_RS17595	COG1021	2,3-dihydroxybenzoate-AMP ligase
KNN_RS17600	COG1169	isochorismate synthase
KNN_RS17605	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS17610	COG2223	nitrite transmembrane transporter activity
KNN_RS17635	COG0419	ATPase involved in DNA repair
KNN_RS17640	COG0420	3'-5' exonuclease activity
KNN_RS17655	COG1024	Enoyl-CoA hydratase
KNN_RS17660	COG1280	lysine exporter protein (LysE YggA)
KNN_RS17670	COG2084	Dehydrogenase
KNN_RS17675	COG1960	acyl-CoA dehydrogenase activity
KNN_RS17680	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KNN_RS17685	COG2079	MmgE PrpD family protein
KNN_RS17690	COG0372	Belongs to the citrate synthase family
KNN_RS17695	COG4841	protein insertion into membrane
KNN_RS17700	COG2814	Major facilitator Superfamily
KNN_RS17710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNN_RS17710	COG4499	WXG100 protein secretion system (Wss), protein YukC
KNN_RS17730	COG0300	oxidoreductase activity
KNN_RS17765	COG2801	Transposase and inactivated derivatives
KNN_RS17835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KNN_RS17840	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KNN_RS17845	COG0671	phosphoesterase, PA-phosphatase related
KNN_RS17855	COG4991	sh3 domain protein
KNN_RS17855	COG3064	Membrane
KNN_RS17855	COG0515	serine threonine protein kinase
KNN_RS17885	COG1509	lysine 2,3-aminomutase activity
KNN_RS17890	COG3829	transcription factor binding
KNN_RS17895	COG0456	acetyltransferase
KNN_RS17900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KNN_RS17905	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KNN_RS17910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KNN_RS17915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KNN_RS17930	COG5506	Protein of unknown function (DUF1694)
KNN_RS17935	COG1012	belongs to the aldehyde dehydrogenase family
KNN_RS17940	COG1253	flavin adenine dinucleotide binding
KNN_RS17975	COG1174	glycine betaine transport
KNN_RS17980	COG0517	IMP dehydrogenase activity
KNN_RS17980	COG1125	glycine betaine transport
KNN_RS18015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KNN_RS18040	COG1064	alcohol dehydrogenase
KNN_RS18045	COG0384	phenazine biosynthesis protein PhzF
KNN_RS18050	COG1737	Transcriptional regulator
KNN_RS18055	COG2197	response regulator
KNN_RS18060	COG4585	Histidine kinase
KNN_RS18060	COG2203	Gaf domain
KNN_RS18065	COG0668	transmembrane transport
KNN_RS18075	COG1051	belongs to the nudix hydrolase family
KNN_RS18080	COG1335	isochorismatase
KNN_RS18100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KNN_RS18105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNN_RS18110	COG0860	N-Acetylmuramoyl-L-alanine amidase
KNN_RS18125	COG0367	asparagine synthase
KNN_RS18130	COG0071	Belongs to the small heat shock protein (HSP20) family
KNN_RS18135	COG1999	signal sequence binding
KNN_RS18145	COG1307	EDD domain protein, DegV family
KNN_RS18155	COG0805	protein transport
KNN_RS18165	COG1272	protein, Hemolysin III
KNN_RS18170	COG2801	Transposase and inactivated derivatives
KNN_RS18180	COG0204	Acyl-transferase
KNN_RS18190	COG0768	penicillin binding
KNN_RS18205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KNN_RS18220	COG0546	phosphoglycolate phosphatase activity
KNN_RS18230	COG4473	ABC transporter
KNN_RS18250	COG3655	Transcriptional regulator
KNN_RS18260	COG0456	acetyltransferase
KNN_RS18270	COG1794	racemase activity, acting on amino acids and derivatives
KNN_RS18280	COG2610	gluconate transmembrane transporter activity
KNN_RS18305	COG0733	neurotransmitter:sodium symporter activity
KNN_RS18310	COG0017	Asparaginyl-tRNA synthetase
KNN_RS18365	COG0018	arginyl-trna synthetase
KNN_RS18370	COG2521	methyltransferase
KNN_RS18370	COG2136	Putative SAM-dependent methyltransferase
KNN_RS18385	COG1413	lyase activity
KNN_RS18390	COG0629	single-stranded DNA binding
KNN_RS18405	COG0488	(ABC) transporter
KNN_RS18410	COG1418	mRNA catabolic process
KNN_RS18425	COG0457	Tetratricopeptide repeat
KNN_RS18450	COG2359	stage V sporulation protein S
KNN_RS18485	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KNN_RS18490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KNN_RS18495	COG2146	nitrite reductase [NAD(P)H] activity
KNN_RS18500	COG1587	Uroporphyrinogen-III synthase
KNN_RS18500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KNN_RS18510	COG1648	precorrin-2 dehydrogenase activity
KNN_RS18525	COG2223	nitrite transmembrane transporter activity
KNN_RS18535	COG0314	molybdopterin synthase activity
KNN_RS18540	COG0303	'Molybdopterin
KNN_RS18545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KNN_RS18550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KNN_RS18555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KNN_RS18560	COG2181	nitrate reductase activity
KNN_RS18565	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KNN_RS18570	COG1140	nitrate reductase beta subunit
KNN_RS18575	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KNN_RS18580	COG0714	Associated with various cellular activities
KNN_RS18585	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KNN_RS18590	COG1305	Transglutaminase-like
KNN_RS18595	COG0386	Belongs to the glutathione peroxidase family
KNN_RS18610	COG0426	domain, Protein
KNN_RS18610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KNN_RS18625	COG1595	DNA-templated transcription, initiation
KNN_RS18630	COG0604	alcohol dehydrogenase
KNN_RS18640	COG0346	lactoylglutathione lyase activity
KNN_RS18665	COG2226	methyltransferase
KNN_RS18690	COG3874	Sporulation protein YtfJ
KNN_RS18765	COG4499	WXG100 protein secretion system (Wss), protein YukC
KNN_RS18800	COG0456	acetyltransferase
KNN_RS18830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNN_RS18835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNN_RS18840	COG1819	glycosyl
KNN_RS18855	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KNN_RS18870	COG0561	phosphatase activity
KNN_RS18880	COG0860	N-Acetylmuramoyl-L-alanine amidase
KNN_RS18895	COG2211	Major facilitator Superfamily
KNN_RS18900	COG0154	amidase activity
KNN_RS18910	COG1876	peptidase activity
KNN_RS18920	COG0860	N-Acetylmuramoyl-L-alanine amidase
KNN_RS18935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KNN_RS18940	COG1114	Component of the transport system for branched-chain amino acids
KNN_RS18955	COG1253	flavin adenine dinucleotide binding
KNN_RS18960	COG2839	Protein conserved in bacteria
KNN_RS18965	COG0702	epimerase
KNN_RS18980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNN_RS18985	COG1607	acyl-coa hydrolase
KNN_RS18995	COG3689	TIGRFAM TIGR03943 family protein
KNN_RS19000	COG0701	Predicted permease
KNN_RS19010	COG2244	polysaccharide biosynthetic process
KNN_RS19015	COG0586	Pfam SNARE associated Golgi protein
KNN_RS19020	COG1051	belongs to the nudix hydrolase family
KNN_RS19025	COG5337	Spore coat protein CotH
KNN_RS19050	COG4166	transmembrane transport
KNN_RS19060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KNN_RS19070	COG0702	epimerase
KNN_RS19080	COG0803	Belongs to the bacterial solute-binding protein 9 family
KNN_RS19085	COG0456	acetyltransferase
KNN_RS19090	COG0523	cobalamin synthesis protein
KNN_RS19095	COG4989	oxidoreductase activity
KNN_RS19100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS19105	COG1231	oxidoreductase activity
KNN_RS19115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNN_RS19130	COG0783	Belongs to the Dps family
KNN_RS19135	COG3949	Membrane
KNN_RS19150	COG0840	transmembrane signaling receptor activity
KNN_RS19175	COG3152	Membrane
KNN_RS19190	COG1404	Belongs to the peptidase S8 family
KNN_RS19195	COG2002	toxin-antitoxin pair type II binding
KNN_RS19200	COG0577	efflux transmembrane transporter activity
KNN_RS19235	COG3547	Transposase (IS116 IS110 IS902 family)
KNN_RS19240	COG1752	Esterase of the alpha-beta hydrolase superfamily
KNN_RS19250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNN_RS19255	COG1279	arginine transmembrane transporter activity
KNN_RS19260	COG2814	Major facilitator Superfamily
KNN_RS19270	COG1082	Xylose isomerase domain protein TIM barrel
KNN_RS19280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNN_RS19300	COG1247	-acetyltransferase
KNN_RS19305	COG2801	Transposase and inactivated derivatives
KNN_RS19315	COG1285	pathogenesis
KNN_RS19330	COG5002	protein histidine kinase activity
KNN_RS19335	COG0745	RESPONSE REGULATOR receiver
KNN_RS19345	COG1316	TRANSCRIPTIONal
KNN_RS19370	COG0460	homoserine dehydrogenase
KNN_RS19400	COG0300	oxidoreductase activity
KNN_RS19410	COG5002	protein histidine kinase activity
KNN_RS19415	COG0745	RESPONSE REGULATOR receiver
KNN_RS19420	COG1132	(ABC) transporter
KNN_RS19585	COG0305	Participates in initiation and elongation during chromosome replication
KNN_RS19685	COG1132	(ABC) transporter
KNN_RS19695	COG0791	NLP P60 protein
KNN_RS19695	COG1388	LysM domain
KNN_RS19710	COG1686	Belongs to the peptidase S11 family
KNN_RS19770	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KNN_RS19775	COG4988	ABC transporter
KNN_RS19780	COG1294	oxidase, subunit
KNN_RS19785	COG1271	oxidase subunit
KNN_RS19805	COG1942	4-Oxalocrotonate Tautomerase
KNN_RS19815	COG0583	DNA-binding transcription factor activity
KNN_RS19845	COG0411	ABC transporter
KNN_RS19865	COG0523	cobalamin synthesis protein
KNN_RS19870	COG1231	oxidoreductase activity
KNN_RS19880	COG0628	permease
KNN_RS19895	COG0778	Nitroreductase
KNN_RS19900	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KNN_RS19905	COG1959	2 iron, 2 sulfur cluster binding
KNN_RS19910	COG0583	DNA-binding transcription factor activity
KNN_RS19915	COG0697	spore germination
KNN_RS19920	COG4549	nuclear export factor GLE1
KNN_RS19925	COG2372	response to copper ion
KNN_RS19925	COG1276	copper resistance
KNN_RS19935	COG1114	Component of the transport system for branched-chain amino acids
KNN_RS19955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KNN_RS19965	COG2132	Multicopper oxidase
KNN_RS19975	COG0006	proline dipeptidase activity
KNN_RS19985	COG4846	Membrane protein involved in cytochrome C biogenesis
KNN_RS19995	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KNN_RS20000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KNN_RS20010	COG2390	Transcriptional regulator
KNN_RS20015	COG1309	transcriptional regulator
KNN_RS20030	COG0456	acetyltransferase
KNN_RS20045	COG2309	aminopeptidase activity
KNN_RS20065	COG0531	amino acid
KNN_RS20075	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KNN_RS20090	COG1914	H( )-stimulated, divalent metal cation uptake system
KNN_RS20095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS20115	COG4166	transmembrane transport
KNN_RS20135	COG0427	acetyl-CoA hydrolase
KNN_RS20140	COG3279	Response regulator of the LytR AlgR family
KNN_RS20150	COG3384	dioxygenase
KNN_RS20155	COG2814	Major facilitator Superfamily
KNN_RS20180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KNN_RS20200	COG0028	Belongs to the TPP enzyme family
KNN_RS20205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KNN_RS20215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNN_RS20240	COG2323	membrane
KNN_RS20245	COG5566	PFAM Mor transcription activator
KNN_RS20255	COG0733	neurotransmitter:sodium symporter activity
KNN_RS20275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KNN_RS20280	COG2223	nitrite transmembrane transporter activity
KNN_RS20285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KNN_RS20295	COG0477	Major facilitator Superfamily
KNN_RS20310	COG1695	Transcriptional regulator
KNN_RS20330	COG2814	Major facilitator Superfamily
KNN_RS20380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KNN_RS20385	COG0784	Response regulator, receiver
KNN_RS20390	COG4191	Histidine kinase
KNN_RS20395	COG0281	malic enzyme
KNN_RS20400	COG1027	Aspartate ammonia-lyase
KNN_RS20410	COG0528	UMP kinase activity
KNN_RS20415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNN_RS20430	COG1131	(ABC) transporter
KNN_RS20435	COG3850	Histidine kinase
KNN_RS20465	COG2733	membrane
KNN_RS20505	COG1484	DNA-dependent DNA replication
KNN_RS20530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNN_RS20530	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNN_RS20780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KNN_RS20800	COG3340	Belongs to the peptidase S51 family
KNN_RS20830	COG0789	Transcriptional regulator
KNN_RS20835	COG1757	Na H antiporter
KNN_RS20850	COG0701	Predicted permease
KNN_RS20855	COG0523	cobalamin synthesis protein
KNN_RS20865	COG0697	spore germination
KNN_RS20870	COG1802	Transcriptional regulator
KNN_RS20900	COG0367	asparagine synthase
KNN_RS20930	COG0406	alpha-ribazole phosphatase activity
KNN_RS20975	COG0583	DNA-binding transcription factor activity
KNN_RS21000	COG2329	Antibiotic biosynthesis monooxygenase
KNN_RS21030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KNN_RS21035	COG4786	Flagellar basal body rod
KNN_RS21040	COG1419	protein localization to endoplasmic reticulum
KNN_RS21045	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KNN_RS21050	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KNN_RS21060	COG1987	bacterial-type flagellum assembly
KNN_RS21065	COG1338	Plays a role in the flagellum-specific transport system
KNN_RS21075	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KNN_RS21075	COG1776	CheC inhibitor of MCP methylation
KNN_RS21080	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KNN_RS21090	COG0741	lytic transglycosylase activity
KNN_RS21095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KNN_RS21110	COG0835	chemotaxis
KNN_RS21110	COG0784	Response regulator, receiver
KNN_RS21125	COG1749	Flagellar hook protein flgE
KNN_RS21145	COG1157	protein secretion by the type III secretion system
KNN_RS21155	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KNN_RS21160	COG1766	The M ring may be actively involved in energy transduction
KNN_RS21170	COG1558	bacterial-type flagellum-dependent cell motility
KNN_RS21175	COG1815	bacterial-type flagellum-dependent cell motility
KNN_RS21195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KNN_RS21200	COG1256	bacterial-type flagellum assembly
KNN_RS21220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KNN_RS21235	COG1776	CheC inhibitor of MCP methylation
KNN_RS21235	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KNN_RS21240	COG0643	Histidine kinase
KNN_RS21240	COG2198	Histidine kinase
KNN_RS21245	COG2201	protein-glutamate methylesterase activity
KNN_RS21250	COG1360	Flagellar Motor Protein
KNN_RS21255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KNN_RS21265	COG1923	regulation of RNA biosynthetic process
KNN_RS21295	COG2801	Transposase and inactivated derivatives
KNN_RS21310	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KNN_RS21315	COG2323	membrane
KNN_RS21325	COG0789	Transcriptional regulator
KNN_RS21325	COG4978	Transcriptional regulator
KNN_RS21330	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNN_RS21335	COG0475	glutathione-regulated potassium exporter activity
KNN_RS21345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KNN_RS21355	COG2801	Transposase and inactivated derivatives
KNN_RS21360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNN_RS21380	COG1280	lysine exporter protein (LysE YggA)
KNN_RS21385	COG3403	YqcI/YcgG family
KNN_RS21420	COG0328	RNA-DNA hybrid ribonuclease activity
KNN_RS21440	COG0454	-acetyltransferase
KNN_RS21455	COG0438	transferase activity, transferring glycosyl groups
KNN_RS21460	COG1215	transferase activity, transferring glycosyl groups
KNN_RS21475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KNN_RS21485	COG3944	biosynthesis protein
KNN_RS21500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNN_RS21550	COG0456	acetyltransferase
KNN_RS21560	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KNN_RS21565	COG2311	Membrane
KNN_RS21570	COG2233	PERMEase
KNN_RS21580	COG0024	Methionine aminopeptidase
KNN_RS21590	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KNN_RS21595	COG1199	ATP-dependent helicase activity
KNN_RS21605	COG0116	Belongs to the methyltransferase superfamily
KNN_RS21660	COG4499	WXG100 protein secretion system (Wss), protein YukC
KNN_RS21660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNN_RS21670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KNN_RS21675	COG3935	DnaD domain protein
KNN_RS21695	COG1199	ATP-dependent helicase activity
KNN_RS21695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KNN_RS21730	COG0438	transferase activity, transferring glycosyl groups
KNN_RS21750	COG1694	Mazg nucleotide pyrophosphohydrolase
KNN_RS21760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNN_RS21770	COG2738	Putative neutral zinc metallopeptidase
KNN_RS21785	COG4347	Protein of unknown function (DUF1405)
KNN_RS21790	COG2010	Cytochrome c
KNN_RS21790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KNN_RS21795	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KNN_RS21815	COG0457	Tetratricopeptide repeat
KNN_RS21845	COG0142	geranyltranstransferase activity
KNN_RS21855	COG0142	geranyltranstransferase activity
KNN_RS21870	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KNN_RS21935	COG0252	asparaginase activity
KNN_RS21940	COG0492	ferredoxin-NADP+ reductase activity
KNN_RS21960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KNN_RS21970	COG0789	Transcriptional regulator
KNN_RS21975	COG1408	metallophosphoesterase
KNN_RS21985	COG1266	CAAX protease self-immunity
KNN_RS21990	COG0514	ATP-dependent DNA helicase (RecQ)
KNN_RS22000	COG1141	Ferredoxin
KNN_RS22005	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KNN_RS22020	COG2096	Adenosyltransferase
KNN_RS22025	COG5002	protein histidine kinase activity
KNN_RS22030	COG0745	RESPONSE REGULATOR receiver
KNN_RS22035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KNN_RS22040	COG1333	cytochrome c biogenesis protein
KNN_RS22050	COG1187	pseudouridine synthase activity
KNN_RS22055	COG0700	Nucleoside recognition
KNN_RS22060	COG2715	membrane protein required for spore maturation
KNN_RS22065	COG1686	Belongs to the peptidase S11 family
KNN_RS22070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KNN_RS22085	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KNN_RS22085	COG0392	lysyltransferase activity
KNN_RS22100	COG5002	protein histidine kinase activity
KNN_RS22105	COG0582	viral genome integration into host DNA
KNN_RS22115	COG1801	Protein of unknown function DUF72
KNN_RS22120	COG3852	Histidine kinase
KNN_RS22135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNN_RS22140	COG1392	Phosphate transport regulator
KNN_RS22145	COG0306	phosphate transporter
KNN_RS22150	COG0730	response to heat
KNN_RS22190	COG2226	methyltransferase
KNN_RS22200	COG1114	Component of the transport system for branched-chain amino acids
KNN_RS22210	COG2197	response regulator
KNN_RS22215	COG4585	Histidine kinase
KNN_RS22220	COG4758	membrane
KNN_RS22235	COG1757	Na H antiporter
KNN_RS22255	COG0733	neurotransmitter:sodium symporter activity
KNN_RS22260	COG1648	precorrin-2 dehydrogenase activity
KNN_RS22280	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KNN_RS22285	COG0529	Catalyzes the synthesis of activated sulfate
KNN_RS22305	COG0019	diaminopimelate decarboxylase activity
KNN_RS22315	COG1368	sulfuric ester hydrolase activity
KNN_RS22320	COG1183	phosphatidylcholine synthase activity
KNN_RS22335	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KNN_RS22410	COG0440	acetolactate synthase activity
KNN_RS22415	COG0028	Belongs to the TPP enzyme family
KNN_RS22420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KNN_RS22440	COG3874	Sporulation protein YtfJ
KNN_RS22445	COG4709	membrane
KNN_RS22450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KNN_RS22455	COG1301	dicarboxylic acid transport
KNN_RS22465	COG1846	Transcriptional regulator
KNN_RS22520	COG3173	Aminoglycoside phosphotransferase
KNN_RS22535	COG0716	FMN binding
KNN_RS22560	COG1696	Membrane protein involved in D-alanine export
KNN_RS22570	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KNN_RS22585	COG2070	2-Nitropropane dioxygenase
KNN_RS22590	COG1619	proteins homologs of microcin C7 resistance protein MccF
KNN_RS22605	COG1335	isochorismatase
KNN_RS22615	COG1522	sequence-specific DNA binding
KNN_RS22635	COG1131	(ABC) transporter
KNN_RS22645	COG1131	(ABC) transporter
KNN_RS22650	COG1725	Transcriptional regulator
KNN_RS22655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNN_RS22660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNN_RS22665	COG1780	Probably involved in ribonucleotide reductase function
KNN_RS22695	COG4873	Protein conserved in bacteria
KNN_RS22710	COG0720	synthase
KNN_RS22720	COG5002	protein histidine kinase activity
KNN_RS22730	COG2318	DinB family
KNN_RS22740	COG1846	Transcriptional regulator
KNN_RS22745	COG3852	Histidine kinase
KNN_RS22755	COG2861	carbohydrate metabolic process
KNN_RS22765	COG0235	Class ii aldolase
KNN_RS22780	COG1349	DNA-binding transcription factor activity
KNN_RS22805	COG3842	ATPase activity
KNN_RS22810	COG1840	ABC-type Fe3 transport system, periplasmic component
KNN_RS22825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KNN_RS22835	COG3243	poly(R)-hydroxyalkanoic acid synthase
KNN_RS22840	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS22860	COG2030	dehydratase
KNN_RS22870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KNN_RS22875	COG0861	Integral membrane protein TerC family
KNN_RS22880	COG2116	formate transmembrane transporter activity
KNN_RS22890	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KNN_RS22910	COG2186	Transcriptional regulator
KNN_RS22915	COG5002	protein histidine kinase activity
KNN_RS22920	COG0745	RESPONSE REGULATOR receiver
KNN_RS22930	COG3835	regulator
KNN_RS22935	COG0277	FAD linked oxidase domain protein
KNN_RS22940	COG0247	lactate metabolic process
KNN_RS22945	COG2340	Cysteine-rich secretory protein family
KNN_RS22955	COG0564	pseudouridine synthase activity
KNN_RS22965	COG2409	Drug exporters of the RND superfamily
KNN_RS22980	COG1177	transmembrane transport
KNN_RS22985	COG1176	ABC-type spermidine putrescine transport system, permease component I
KNN_RS22995	COG1012	belongs to the aldehyde dehydrogenase family
KNN_RS23030	COG0681	Belongs to the peptidase S26 family
KNN_RS23045	COG1686	Belongs to the peptidase S11 family
KNN_RS23100	COG0508	dehydrogenase complex catalyzes the overall conversion of
KNN_RS23150	COG5634	Uncharacterized conserved protein (DUF2278)
KNN_RS23155	COG1620	l-lactate permease
KNN_RS23190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KNN_RS23190	COG0512	Glutamine amidotransferase of anthranilate synthase
KNN_RS23200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNN_RS23225	COG2382	esterase
KNN_RS23235	COG2153	protein acetylation
KNN_RS23280	COG1091	dTDP-4-dehydrorhamnose reductase activity
KNN_RS23295	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KNN_RS23315	COG0457	Tetratricopeptide repeat
KNN_RS23315	COG0463	Glycosyl transferase, family 2
KNN_RS23335	COG1216	Glycosyl transferase, family 2
KNN_RS23340	COG0772	Belongs to the SEDS family
KNN_RS23355	COG0564	pseudouridine synthase activity
KNN_RS23365	COG2357	RelA SpoT domain protein
KNN_RS23375	COG4116	CYTH
KNN_RS23380	COG2346	COG2346, Truncated hemoglobins
KNN_RS23400	COG1164	Oligoendopeptidase f
KNN_RS23420	COG0861	Integral membrane protein TerC family
KNN_RS23435	COG4166	transmembrane transport
KNN_RS23440	COG0534	Mate efflux family protein
KNN_RS23445	COG4608	Belongs to the ABC transporter superfamily
KNN_RS23450	COG0444	Belongs to the ABC transporter superfamily
KNN_RS23455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNN_RS23460	COG0601	transmembrane transport
KNN_RS23465	COG4166	transmembrane transport
KNN_RS23475	COG0180	Tryptophanyl-tRNA synthetase
KNN_RS23485	COG5504	Zn-dependent protease
KNN_RS23490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KNN_RS23510	COG2267	carboxylic ester hydrolase activity
KNN_RS23530	COG0561	phosphatase activity
KNN_RS23545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNN_RS23555	COG2996	Protein conserved in bacteria
KNN_RS23575	COG0004	ammonium transporteR
KNN_RS23580	COG0753	catalase activity
KNN_RS23620	COG5632	N-Acetylmuramoyl-L-alanine amidase
KNN_RS23825	COG0367	asparagine synthase
KNN_RS23850	COG0179	Fumarylacetoacetate (FAA) hydrolase
KNN_RS23910	COG0398	Pfam SNARE associated Golgi protein
KNN_RS23940	COG1388	LysM domain
KNN_RS23940	COG5632	N-Acetylmuramoyl-L-alanine amidase
KNN_RS23940	COG3409	Peptidoglycan-binding domain 1 protein
KNN_RS23945	COG4824	toxin secretion phage lysis holin
KNN_RS24045	COG5484	DNA packaging
KNN_RS24085	COG1595	DNA-templated transcription, initiation
KNN_RS24095	COG3331	DNA recombination
KNN_RS24195	COG1396	sequence-specific DNA binding
KNN_RS24205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KNN_RS24240	COG2224	Isocitrate lyase
KNN_RS24245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KNN_RS24255	COG3693	PFAM glycoside hydrolase, family 10
KNN_RS24260	COG0840	transmembrane signaling receptor activity
KNN_RS24265	COG0501	Belongs to the peptidase M48B family
KNN_RS24285	COG0745	RESPONSE REGULATOR receiver
KNN_RS24290	COG2205	protein histidine kinase activity
KNN_RS24295	COG3547	Transposase (IS116 IS110 IS902 family)
KNN_RS24300	COG3708	Transcriptional regulator
KNN_RS24300	COG2207	Transcriptional regulator
KNN_RS24305	COG1595	DNA-templated transcription, initiation
KNN_RS24315	COG1078	dGTPase activity
KNN_RS24320	COG1408	metallophosphoesterase
KNN_RS24335	COG4208	sulfate ABC transporter
KNN_RS24345	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KNN_RS24355	COG0318	PFAM AMP-dependent synthetase and ligase
KNN_RS24365	COG0095	Lipoate-protein ligase
KNN_RS24370	COG1234	tRNA 3'-trailer cleavage
KNN_RS24380	COG1609	Transcriptional regulator
KNN_RS24385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KNN_RS24395	COG1511	domain protein
KNN_RS24400	COG1309	transcriptional regulator
KNN_RS24435	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KNN_RS24450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNN_RS24455	COG2329	Antibiotic biosynthesis monooxygenase
KNN_RS24460	COG3428	Bacterial PH domain
KNN_RS24465	COG3402	PFAM membrane-flanked domain
KNN_RS24470	COG0697	spore germination
KNN_RS24505	COG3428	Bacterial PH domain
KNN_RS24510	COG3402	PFAM membrane-flanked domain
KNN_RS24530	COG4473	ABC transporter
KNN_RS24535	COG1131	(ABC) transporter
KNN_RS24540	COG0537	adenosine 5'-monophosphoramidase activity
KNN_RS24545	COG4980	gas vesicle protein
KNN_RS24565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KNN_RS24575	COG3973	AAA domain
KNN_RS24590	COG1695	Transcriptional regulator
KNN_RS24595	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KNN_RS24605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KNN_RS24610	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KNN_RS24620	COG2140	Oxalate decarboxylase
KNN_RS24650	COG2267	carboxylic ester hydrolase activity
KNN_RS24660	COG0457	Tetratricopeptide repeat
KNN_RS24665	COG0346	lactoylglutathione lyase activity
KNN_RS24670	COG0346	lactoylglutathione lyase activity
KNN_RS24680	COG4717	serine-type aminopeptidase activity
KNN_RS24685	COG0420	3'-5' exonuclease activity
KNN_RS24705	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KNN_RS24715	COG3344	reverse transcriptase
KNN_RS24745	COG5002	protein histidine kinase activity
KNN_RS24745	COG0784	Response regulator, receiver
KNN_RS24745	COG2205	protein histidine kinase activity
KNN_RS24750	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KNN_RS24755	COG2208	phosphoserine phosphatase activity
KNN_RS24765	COG1191	sigma factor activity
KNN_RS24855	COG2373	Large extracellular alpha-helical protein
KNN_RS24875	COG0457	Tetratricopeptide repeat
KNN_RS24900	COG2376	Dihydroxyacetone kinase
KNN_RS24910	COG2376	Dihydroxyacetone kinase
KNN_RS24925	COG3344	reverse transcriptase
KNN_RS24945	COG3344	reverse transcriptase
KNN_RS25060	COG0457	Tetratricopeptide repeat
KNN_RS25080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNN_RS25090	COG4608	Belongs to the ABC transporter superfamily
KNN_RS25095	COG0444	Belongs to the ABC transporter superfamily
KNN_RS25100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNN_RS25105	COG0601	transmembrane transport
KNN_RS25145	COG1363	Peptidase, m42
KNN_RS25165	COG1024	Enoyl-CoA hydratase
KNN_RS25185	COG2244	polysaccharide biosynthetic process
KNN_RS25190	COG0659	secondary active sulfate transmembrane transporter activity
KNN_RS25205	COG0318	PFAM AMP-dependent synthetase and ligase
KNN_RS25210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KNN_RS25215	COG3409	Peptidoglycan-binding domain 1 protein
KNN_RS25215	COG5632	N-Acetylmuramoyl-L-alanine amidase
KNN_RS25225	COG0561	phosphatase activity
KNN_RS25235	COG3527	Alpha-acetolactate decarboxylase
KNN_RS25240	COG0028	Belongs to the TPP enzyme family
KNN_RS25245	COG2197	response regulator
KNN_RS25250	COG4585	Histidine kinase
KNN_RS25270	COG0189	ligase activity
KNN_RS25285	COG1126	abc transporter atp-binding protein
KNN_RS25290	COG0765	amino acid transport
KNN_RS25295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNN_RS25300	COG3547	Transposase (IS116 IS110 IS902 family)
KNN_RS25305	COG1132	(ABC) transporter
KNN_RS25310	COG1132	(ABC) transporter
KNN_RS25315	COG1012	belongs to the aldehyde dehydrogenase family
KNN_RS25335	COG0531	amino acid
KNN_RS25345	COG0753	catalase activity
KNN_RS25345	COG0693	protein deglycase activity
KNN_RS25350	COG0693	protein deglycase activity
KNN_RS25360	COG2211	Major facilitator Superfamily
KNN_RS25365	COG4533	DNA binding
KNN_RS25370	COG2249	NAD(P)H dehydrogenase (quinone) activity
KNN_RS25380	COG1733	regulation of RNA biosynthetic process
KNN_RS25385	COG2814	Major facilitator Superfamily
KNN_RS25390	COG1309	transcriptional regulator
KNN_RS25410	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS25415	COG0165	Argininosuccinate lyase
KNN_RS25415	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KNN_RS25420	COG1522	sequence-specific DNA binding
KNN_RS25440	COG2259	Doxx family
KNN_RS25450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KNN_RS25450	COG1263	PTS System
KNN_RS25460	COG1737	Transcriptional regulator
KNN_RS25470	COG0475	glutathione-regulated potassium exporter activity
KNN_RS25475	COG0531	amino acid
KNN_RS25505	COG0586	Pfam SNARE associated Golgi protein
KNN_RS25540	COG3546	catalase activity
KNN_RS25545	COG1114	Component of the transport system for branched-chain amino acids
KNN_RS25560	COG5522	Integral membrane protein (intg_mem_TP0381)
KNN_RS25570	COG1136	(ABC) transporter
KNN_RS25575	COG0577	efflux transmembrane transporter activity
KNN_RS25580	COG1388	LysM domain
KNN_RS25580	COG3584	3D domain protein
KNN_RS25585	COG2801	Transposase and inactivated derivatives
KNN_RS25610	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KNN_RS25615	COG1447	Phosphotransferase system cellobiose-specific component IIA
KNN_RS25620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KNN_RS25620	COG3711	transcriptional antiterminator
KNN_RS25635	COG1283	sodium-dependent phosphate transmembrane transporter activity
KNN_RS25640	COG0604	alcohol dehydrogenase
KNN_RS25645	COG1316	TRANSCRIPTIONal
KNN_RS25655	COG0730	response to heat
KNN_RS25660	COG2210	Belongs to the sulfur carrier protein TusA family
KNN_RS25670	COG0425	Belongs to the sulfur carrier protein TusA family
KNN_RS25670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNN_RS25675	COG0425	Belongs to the sulfur carrier protein TusA family
KNN_RS25680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KNN_RS25680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNN_RS25685	COG0425	Belongs to the sulfur carrier protein TusA family
KNN_RS25685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNN_RS25690	COG1937	Protein conserved in bacteria
KNN_RS25695	COG0446	pyridine nucleotide-disulphide oxidoreductase
KNN_RS25710	COG1414	Transcriptional regulator
KNN_RS25720	COG2719	SpoVR family
KNN_RS25725	COG0778	Nitroreductase
KNN_RS25775	COG1609	Transcriptional regulator
KNN_RS25780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KNN_RS25780	COG1263	PTS System
KNN_RS25785	COG1621	beta-fructofuranosidase activity
KNN_RS25790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNN_RS25805	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS25810	COG2252	PERMEase
KNN_RS25820	COG1129	ABC transporter
KNN_RS25825	COG1172	Belongs to the binding-protein-dependent transport system permease family
KNN_RS25840	COG1136	(ABC) transporter
KNN_RS25865	COG1846	Transcriptional regulator
KNN_RS25870	COG2814	Major facilitator Superfamily
KNN_RS25875	COG2205	protein histidine kinase activity
KNN_RS25915	COG0351	phosphomethylpyrimidine kinase
KNN_RS25920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KNN_RS25930	COG2104	thiamine diphosphate biosynthetic process
KNN_RS25935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KNN_RS25940	COG0352	thiamine-phosphate diphosphorylase activity
KNN_RS25945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KNN_RS25950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNN_RS25955	COG1116	anion transmembrane transporter activity
KNN_RS25960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KNN_RS25980	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KNN_RS26100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KNN_RS26105	COG0581	inorganic phosphate transmembrane transporter activity
KNN_RS26110	COG0573	inorganic phosphate transmembrane transporter activity
KNN_RS26115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KNN_RS26120	COG1918	ferrous iron import across plasma membrane
KNN_RS26120	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KNN_RS26125	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KNN_RS26130	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KNN_RS26140	COG0531	amino acid
KNN_RS26145	COG0697	spore germination
KNN_RS26150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNN_RS26165	COG4990	cell redox homeostasis
KNN_RS26170	COG0833	amino acid
KNN_RS26180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KNN_RS26195	COG0475	glutathione-regulated potassium exporter activity
KNN_RS26195	COG0569	domain protein
KNN_RS26205	COG2153	protein acetylation
KNN_RS26230	COG2252	PERMEase
KNN_RS26235	COG1113	amino acid transport
KNN_RS26250	COG1114	Component of the transport system for branched-chain amino acids
KNN_RS26255	COG3104	oligopeptide transport
KNN_RS26265	COG2801	Transposase and inactivated derivatives
KNN_RS26285	COG1476	TRANSCRIPTIONal
KNN_RS26290	COG3583	domain protein
KNN_RS26290	COG3584	3D domain protein
KNN_RS26295	COG0840	transmembrane signaling receptor activity
KNN_RS26340	COG1674	ftsk spoiiie
KNN_RS26430	COG0740	serine-type endopeptidase activity
KNN_RS26440	COG1802	Transcriptional regulator
KNN_RS26440	COG4626	Terminase
KNN_RS26490	COG0582	viral genome integration into host DNA
KNN_RS26570	COG1396	sequence-specific DNA binding
KNN_RS26600	COG1063	alcohol dehydrogenase
KNN_RS26620	COG1879	ABC-type sugar transport system periplasmic component
KNN_RS26625	COG1172	Belongs to the binding-protein-dependent transport system permease family
KNN_RS26640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNN_RS26645	COG1609	Transcriptional regulator
KNN_RS26650	COG0477	Major facilitator Superfamily
KNN_RS26655	COG1846	Transcriptional regulator
KNN_RS26660	COG2271	Major facilitator Superfamily
KNN_RS26675	COG0659	secondary active sulfate transmembrane transporter activity
KNN_RS26705	COG5002	protein histidine kinase activity
KNN_RS26710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KNN_RS26715	COG2378	regulation of single-species biofilm formation
KNN_RS26725	COG1595	DNA-templated transcription, initiation
KNN_RS26740	COG0833	amino acid
KNN_RS26745	COG0765	amino acid transport
KNN_RS26750	COG0765	amino acid transport
KNN_RS26755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNN_RS26760	COG1126	abc transporter atp-binding protein
KNN_RS26770	COG1115	amino acid carrier protein
KNN_RS26775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KNN_RS26785	COG1404	Belongs to the peptidase S8 family
KNN_RS26790	COG2197	response regulator
KNN_RS26795	COG4585	Histidine kinase
KNN_RS26800	COG0697	spore germination
KNN_RS26815	COG0366	Alpha amylase catalytic
KNN_RS26820	COG1263	PTS System
KNN_RS26820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KNN_RS26825	COG2188	Transcriptional regulator
KNN_RS26830	COG0531	amino acid
KNN_RS26840	COG2801	Transposase and inactivated derivatives
KNN_RS26870	COG0714	Associated with various cellular activities
KNN_RS26875	COG4548	von Willebrand factor, type A
KNN_RS26885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KNN_RS26905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNN_RS26910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNN_RS26915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNN_RS26920	COG3104	oligopeptide transport
KNN_RS26935	COG1620	l-lactate permease
KNN_RS26940	COG1027	Aspartate ammonia-lyase
KNN_RS26945	COG1253	flavin adenine dinucleotide binding
KNN_RS26950	COG3547	Transposase (IS116 IS110 IS902 family)
KNN_RS26955	COG0346	lactoylglutathione lyase activity
KNN_RS26960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KNN_RS26965	COG1316	TRANSCRIPTIONal
KNN_RS26970	COG2720	vancomycin resistance protein
KNN_RS26990	COG3227	Zinc metalloprotease (Elastase)
KNN_RS27000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KNN_RS27005	COG2217	Heavy metal translocating P-type atpase
KNN_RS27010	COG0640	Transcriptional regulator
KNN_RS27015	COG0531	amino acid
KNN_RS27055	COG2427	Protein of unknown function (DUF1641)
KNN_RS27060	COG3383	formate dehydrogenase (NAD+) activity
KNN_RS27065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KNN_RS27085	COG5002	protein histidine kinase activity
KNN_RS27095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KNN_RS27100	COG0697	spore germination
KNN_RS27110	COG0281	malic enzyme
KNN_RS27115	COG3493	citrate carrier protein
KNN_RS27120	COG4565	transcriptional regulatory protein
KNN_RS27125	COG3290	protein histidine kinase activity
KNN_RS27135	COG4990	cell redox homeostasis
KNN_RS27145	COG5002	protein histidine kinase activity
KNN_RS27150	COG0745	RESPONSE REGULATOR receiver
KNN_RS27155	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KNN_RS27165	COG0395	ABC-type sugar transport system, permease component
KNN_RS27170	COG1175	transmembrane transport
KNN_RS27175	COG3842	ATPase activity
KNN_RS27180	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KNN_RS27205	COG2851	Citrate transporter
KNN_RS27210	COG4565	transcriptional regulatory protein
KNN_RS27215	COG3290	protein histidine kinase activity
KNN_RS27225	COG2268	Band 7 protein
KNN_RS27230	COG1585	Membrane protein implicated in regulation of membrane protease activity
KNN_RS27240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KNN_RS27260	COG2766	serine protein kinase
KNN_RS27270	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KNN_RS27295	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KNN_RS27420	COG2801	Transposase and inactivated derivatives
KNN_RS27425	COG0735	belongs to the Fur family
KNN_RS27430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KNN_RS27450	COG4555	ABC transporter
KNN_RS27460	COG0070	glutamate synthase
KNN_RS27460	COG0067	glutamate synthase
KNN_RS27460	COG0069	glutamate synthase activity
KNN_RS27465	COG4129	membrane
KNN_RS27470	COG1132	(ABC) transporter
KNN_RS27495	COG1194	a g-specific adenine glycosylase
KNN_RS27500	COG1988	membrane-bound metal-dependent
KNN_RS27530	COG1090	epimerase
KNN_RS27535	COG1228	amidohydrolase
KNN_RS27565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KNN_RS27585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KNN_RS27585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KNN_RS27595	COG0463	Glycosyl transferase, family 2
KNN_RS27610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KNN_RS27615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KNN_RS27615	COG1263	PTS System
KNN_RS27640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KNN_RS27645	COG0833	amino acid
KNN_RS27670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KNN_RS27675	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KNN_RS27695	COG0535	radical SAM domain protein
KNN_RS27705	COG0387	Pfam Sodium calcium exchanger
KNN_RS27710	COG3871	stress protein (general stress protein 26)
KNN_RS27725	COG0586	Pfam SNARE associated Golgi protein
KNN_RS27735	COG0681	Belongs to the peptidase S26 family
KNN_RS27745	COG0697	spore germination
KNN_RS27750	COG2217	Heavy metal translocating P-type atpase
KNN_RS27755	COG1295	ribonuclease BN
KNN_RS27765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KNN_RS27790	COG3853	Toxic anion resistance protein (TelA)
KNN_RS27800	COG0861	Integral membrane protein TerC family
KNN_RS27805	COG2310	stress, protein
KNN_RS27810	COG2310	stress, protein
KNN_RS27815	COG2310	stress, protein
KNN_RS27845	COG2270	Major facilitator Superfamily
KNN_RS27850	COG2801	Transposase and inactivated derivatives
KNN_RS27900	COG1116	anion transmembrane transporter activity
KNN_RS27905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KNN_RS27910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KNN_RS27930	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KNN_RS27960	COG2190	(PTS) system
KNN_RS27960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KNN_RS27960	COG1263	PTS System
KNN_RS27965	COG0366	Alpha amylase catalytic
KNN_RS27970	COG0277	FAD linked oxidase domain protein
KNN_RS27980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KNN_RS27985	COG0549	Belongs to the carbamate kinase family
KNN_RS28010	COG0840	transmembrane signaling receptor activity
KNN_RS28015	COG1126	abc transporter atp-binding protein
KNN_RS28020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KNN_RS28025	COG0765	amino acid transport
KNN_RS28035	COG0723	plastoquinol--plastocyanin reductase activity
KNN_RS28035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KNN_RS28040	COG2814	Major facilitator Superfamily
KNN_RS28045	COG3541	Predicted nucleotidyltransferase
KNN_RS28065	COG5002	protein histidine kinase activity
KNN_RS28090	COG0166	Belongs to the GPI family
KNN_RS28100	COG0492	ferredoxin-NADP+ reductase activity
KNN_RS28105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KNN_RS28110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNN_RS28115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNN_RS28135	COG0450	alkyl hydroperoxide reductase
KNN_RS28155	COG1473	amidohydrolase
KNN_RS28160	COG1757	Na H antiporter
KNN_RS28185	COG4807	Protein conserved in bacteria
KNN_RS28190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KNN_RS28200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KNN_RS28215	COG2309	aminopeptidase activity
KNN_RS28225	COG2076	Multidrug Resistance protein
KNN_RS28230	COG1012	belongs to the aldehyde dehydrogenase family
KNN_RS28240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KNN_RS28250	COG1597	lipid kinase activity
KNN_RS28305	COG1388	LysM domain
KNN_RS28305	COG5632	N-Acetylmuramoyl-L-alanine amidase
KNN_RS28305	COG3409	Peptidoglycan-binding domain 1 protein
KNN_RS28375	COG0740	serine-type endopeptidase activity
KNN_RS28385	COG1802	Transcriptional regulator
KNN_RS28385	COG4626	Terminase
KNN_RS28420	COG1674	ftsk spoiiie
KNN_RS28420	COG4980	gas vesicle protein
KNN_RS28425	COG0582	viral genome integration into host DNA
KNN_RS28445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KNN_RS28495	COG1396	sequence-specific DNA binding
KNN_RS28515	COG1846	Transcriptional regulator
KNN_RS28520	COG0003	Pfam Anion-transporting ATPase
KNN_RS28535	COG1464	Belongs to the NlpA lipoprotein family
KNN_RS28540	COG2011	ABC-type metal ion transport system permease component
KNN_RS28550	COG1335	isochorismatase
KNN_RS28565	COG4851	CamS sex pheromone cAM373 precursor
KNN_RS28575	COG0210	DNA helicase
KNN_RS28600	COG0151	Belongs to the GarS family
KNN_RS28610	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KNN_RS28620	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KNN_RS28635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNN_RS28645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KNN_RS28650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KNN_RS28655	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KNN_RS28680	COG1215	transferase activity, transferring glycosyl groups
KNN_RS28700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KNN_RS28710	COG2226	methyltransferase
KNN_RS28740	COG0745	RESPONSE REGULATOR receiver
KNN_RS28745	COG2205	protein histidine kinase activity
KNN_RS28785	COG5002	protein histidine kinase activity
KNN_RS28795	COG2252	PERMEase
KNN_RS28855	COG3378	Phage plasmid primase P4 family
KNN_RS28875	COG0582	viral genome integration into host DNA
KNN_RS28890	COG1266	CAAX protease self-immunity
KNN_RS28905	COG0488	(ABC) transporter
KNN_RS28915	COG0456	acetyltransferase
KNN_RS28920	COG1214	PFAM Peptidase M22, glycoprotease
KNN_RS28925	COG0802	atpase or kinase
KNN_RS29020	COG2183	response to ionizing radiation
KNN_RS29025	COG2337	Toxic component of a toxin-antitoxin (TA) module
KNN_RS29030	COG0864	Transcriptional regulator
KNN_RS29035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KNN_RS29040	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KNN_RS29050	COG0705	Rhomboid family
KNN_RS29055	COG4294	response to UV
KNN_RS29060	COG2801	Transposase and inactivated derivatives
KNN_RS29075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KNN_RS29085	COG2814	Major facilitator Superfamily
KNN_RS29090	COG0531	amino acid
KNN_RS29100	COG0179	Fumarylacetoacetate (FAA) hydrolase
KNN_RS29105	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KNN_RS29135	COG0561	phosphatase activity
KNN_RS29140	COG4608	Belongs to the ABC transporter superfamily
KNN_RS29145	COG0444	Belongs to the ABC transporter superfamily
KNN_RS29150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNN_RS29155	COG0601	transmembrane transport
KNN_RS29170	COG0747	negative chemotaxis
KNN_RS29180	COG0488	(ABC) transporter
KNN_RS29195	COG2801	Transposase and inactivated derivatives
KNN_RS29210	COG5298	Protein conserved in bacteria
KNN_RS29230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNN_RS29240	COG1609	Transcriptional regulator
KNN_RS29245	COG0204	Acyl-transferase
KNN_RS29255	COG0697	spore germination
KNN_RS29265	COG1910	domain protein
KNN_RS29270	COG0725	ABC transporter, periplasmic molybdate-binding protein
KNN_RS29275	COG4149	molybdate abc transporter
KNN_RS29290	COG0656	L-ascorbic acid biosynthetic process
KNN_RS29305	COG4166	transmembrane transport
KNN_RS29310	COG4166	transmembrane transport
KNN_RS29325	COG2207	Transcriptional regulator
KNN_RS29345	COG2814	Major facilitator Superfamily
KNN_RS29355	COG2271	Major facilitator Superfamily
KNN_RS29360	COG0277	FAD linked oxidase domain protein
KNN_RS29370	COG0604	alcohol dehydrogenase
KNN_RS29375	COG1464	Belongs to the NlpA lipoprotein family
KNN_RS29380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KNN_RS29385	COG2011	ABC-type metal ion transport system permease component
KNN_RS29390	COG1028	Short-chain dehydrogenase reductase Sdr
KNN_RS29430	COG4856	YbbR-like protein
KNN_RS29435	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KNN_RS29515	COG0726	polysaccharide deacetylase
KNN_RS29520	COG2194	sulfuric ester hydrolase activity
KNN_RS29530	COG0489	protein tyrosine kinase activity
KNN_RS29535	COG0860	N-Acetylmuramoyl-L-alanine amidase
KNN_RS29560	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNN_RS29595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KNN_RS29605	COG0024	Methionine aminopeptidase
KNN_RS29615	COG0201	protein transport
KNN_RS29675	COG0255	Belongs to the universal ribosomal protein uL29 family
KNN_RS29740	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KNN_RS29745	COG1358	cellular component organization or biogenesis
KNN_RS29760	COG2813	Specifically methylates the guanine in position
KNN_RS29780	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KNN_RS29785	COG0250	Participates in transcription elongation, termination and antitermination
KNN_RS29790	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KNN_RS29800	COG3688	RNA-binding protein containing a PIN domain
KNN_RS29805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNN_RS29820	COG1045	serine acetyltransferase
KNN_RS29840	COG4956	integral membrane protein (PIN domain superfamily)
KNN_RS29850	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KNN_RS29855	COG0542	response to heat
KNN_RS29865	COG3880	PFAM UvrB UvrC protein
KNN_RS29955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KNN_RS29960	COG1396	sequence-specific DNA binding
KNN_RS29965	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KNN_RS29970	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KNN_RS29975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KNN_RS29980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KNN_RS29985	COG0512	Glutamine amidotransferase of anthranilate synthase
KNN_RS29990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KNN_RS29995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KNN_RS30010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KNN_RS30015	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KNN_RS30025	COG2208	phosphoserine phosphatase activity
KNN_RS30040	COG1098	S1 RNA binding domain
KNN_RS30060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KNN_RS30065	COG3956	TIGRFAM MazG family protein
KNN_RS30070	COG2244	polysaccharide biosynthetic process
KNN_RS30075	COG2002	toxin-antitoxin pair type II binding
KNN_RS30080	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KNN_RS30110	COG0251	oxidation-reduction process
KNN_RS30115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KNN_RS30130	COG4466	Protein conserved in bacteria
KNN_RS30150	COG0084	hydrolase, TatD family'
KNN_RS30160	COG2002	toxin-antitoxin pair type II binding
KNN_RS30165	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KNN_RS30175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KNN_RS30185	COG1774	PSP1 C-terminal conserved region
KNN_RS30190	COG0470	DNA polymerase III
KNN_RS30200	COG1982	Orn Lys Arg decarboxylase major
KNN_RS30255	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNN_RS30265	COG0590	tRNA wobble adenosine to inosine editing
KNN_RS30270	COG1335	isochorismatase
KNN_RS30275	COG1428	Deoxynucleoside kinase
KNN_RS30280	COG1428	Deoxynucleoside kinase
KNN_RS30310	COG1686	Belongs to the peptidase S11 family
KNN_RS30315	COG0516	GMP reductase activity
KNN_RS30315	COG0517	IMP dehydrogenase activity
KNN_RS30350	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNN_RS30355	COG0187	DNA topoisomerase II activity
KNN_RS30365	COG2501	S4 domain
KNN_RS30370	COG0592	DNA-directed DNA polymerase activity
KNN_RS30495	COG5002	protein histidine kinase activity
KNN_RS30565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KNN_RS30785	COG0460	homoserine dehydrogenase
KNN_RS30840	COG0280	phosphate acetyltransferase
KNN_RS30905	COG1619	proteins homologs of microcin C7 resistance protein MccF
KNN_RS31355	COG1620	l-lactate permease
KNN_RS31395	COG0583	DNA-binding transcription factor activity
KNN_RS31480	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KNN_RS31480	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KNN_RS31500	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KNN_RS31870	COG1051	belongs to the nudix hydrolase family
KNN_RS32090	COG0012	GTP binding
KNN_RS32415	COG2199	diguanylate cyclase activity
KNN_RS32720	COG0024	Methionine aminopeptidase
KNN_RS32985	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KNN_RS33165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KNN_RS33175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KNN_RS33455	COG5002	protein histidine kinase activity
KNN_RS33705	COG0351	phosphomethylpyrimidine kinase
KNN_RS33870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KNN_RS33880	COG0789	Transcriptional regulator
KNN_RS34470	COG1192	Involved in chromosome partitioning
KNN_RS34490	COG0668	transmembrane transport