locus-tag	class	description
GFH33_RS00010	COG0592	DNA-directed DNA polymerase activity
GFH33_RS00015	COG2501	S4 domain
GFH33_RS00025	COG0187	DNA topoisomerase II activity
GFH33_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GFH33_RS00065	COG0516	GMP reductase activity
GFH33_RS00065	COG0517	IMP dehydrogenase activity
GFH33_RS00070	COG1686	Belongs to the peptidase S11 family
GFH33_RS00100	COG1428	Deoxynucleoside kinase
GFH33_RS00105	COG1428	Deoxynucleoside kinase
GFH33_RS00110	COG1335	isochorismatase
GFH33_RS00115	COG0590	tRNA wobble adenosine to inosine editing
GFH33_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GFH33_RS00180	COG1982	Orn Lys Arg decarboxylase major
GFH33_RS00190	COG0470	DNA polymerase III
GFH33_RS00195	COG1774	PSP1 C-terminal conserved region
GFH33_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GFH33_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GFH33_RS00220	COG2002	toxin-antitoxin pair type II binding
GFH33_RS00230	COG0084	hydrolase, TatD family'
GFH33_RS00250	COG4466	Protein conserved in bacteria
GFH33_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GFH33_RS00270	COG0251	oxidation-reduction process
GFH33_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GFH33_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GFH33_RS00305	COG2002	toxin-antitoxin pair type II binding
GFH33_RS00310	COG2244	polysaccharide biosynthetic process
GFH33_RS00315	COG3956	TIGRFAM MazG family protein
GFH33_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GFH33_RS00340	COG1098	S1 RNA binding domain
GFH33_RS00355	COG2208	phosphoserine phosphatase activity
GFH33_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GFH33_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFH33_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GFH33_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GFH33_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
GFH33_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GFH33_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GFH33_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GFH33_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GFH33_RS00420	COG1396	sequence-specific DNA binding
GFH33_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GFH33_RS00515	COG3880	PFAM UvrB UvrC protein
GFH33_RS00525	COG0542	response to heat
GFH33_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GFH33_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
GFH33_RS00560	COG1045	serine acetyltransferase
GFH33_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFH33_RS00580	COG3688	RNA-binding protein containing a PIN domain
GFH33_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GFH33_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
GFH33_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GFH33_RS00625	COG2813	Specifically methylates the guanine in position
GFH33_RS00640	COG1358	cellular component organization or biogenesis
GFH33_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GFH33_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
GFH33_RS00770	COG0201	protein transport
GFH33_RS00780	COG0024	Methionine aminopeptidase
GFH33_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GFH33_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GFH33_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
GFH33_RS00855	COG0489	protein tyrosine kinase activity
GFH33_RS00865	COG2194	sulfuric ester hydrolase activity
GFH33_RS00870	COG0726	polysaccharide deacetylase
GFH33_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GFH33_RS00955	COG4856	YbbR-like protein
GFH33_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS00995	COG2011	ABC-type metal ion transport system permease component
GFH33_RS01000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GFH33_RS01005	COG1464	Belongs to the NlpA lipoprotein family
GFH33_RS01010	COG0604	alcohol dehydrogenase
GFH33_RS01020	COG0277	FAD linked oxidase domain protein
GFH33_RS01025	COG2271	Major facilitator Superfamily
GFH33_RS01035	COG2814	Major facilitator Superfamily
GFH33_RS01050	COG2207	Transcriptional regulator
GFH33_RS01065	COG4166	transmembrane transport
GFH33_RS01070	COG4166	transmembrane transport
GFH33_RS01080	COG0656	L-ascorbic acid biosynthetic process
GFH33_RS01095	COG4149	molybdate abc transporter
GFH33_RS01100	COG0725	ABC transporter, periplasmic molybdate-binding protein
GFH33_RS01105	COG1910	domain protein
GFH33_RS01120	COG0697	spore germination
GFH33_RS01135	COG0204	Acyl-transferase
GFH33_RS01145	COG1609	Transcriptional regulator
GFH33_RS01155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFH33_RS01170	COG5298	Protein conserved in bacteria
GFH33_RS01195	COG0488	(ABC) transporter
GFH33_RS01205	COG0747	negative chemotaxis
GFH33_RS01220	COG3344	reverse transcriptase
GFH33_RS01235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFH33_RS01240	COG0444	Belongs to the ABC transporter superfamily
GFH33_RS01245	COG4608	Belongs to the ABC transporter superfamily
GFH33_RS01255	COG0561	phosphatase activity
GFH33_RS01285	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GFH33_RS01290	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFH33_RS01300	COG0531	amino acid
GFH33_RS01305	COG2814	Major facilitator Superfamily
GFH33_RS01315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GFH33_RS01325	COG4294	response to UV
GFH33_RS01330	COG0705	Rhomboid family
GFH33_RS01340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GFH33_RS01345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GFH33_RS01350	COG0864	Transcriptional regulator
GFH33_RS01355	COG2337	Toxic component of a toxin-antitoxin (TA) module
GFH33_RS01360	COG2183	response to ionizing radiation
GFH33_RS01460	COG0802	atpase or kinase
GFH33_RS01465	COG1214	PFAM Peptidase M22, glycoprotease
GFH33_RS01470	COG0456	acetyltransferase
GFH33_RS01480	COG0488	(ABC) transporter
GFH33_RS01495	COG1266	CAAX protease self-immunity
GFH33_RS01510	COG0582	viral genome integration into host DNA
GFH33_RS01535	COG3378	Phage plasmid primase P4 family
GFH33_RS01600	COG0582	viral genome integration into host DNA
GFH33_RS01750	COG0582	viral genome integration into host DNA
GFH33_RS01850	COG4824	toxin secretion phage lysis holin
GFH33_RS01885	COG2252	PERMEase
GFH33_RS01895	COG5002	protein histidine kinase activity
GFH33_RS01920	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GFH33_RS01960	COG2205	protein histidine kinase activity
GFH33_RS01965	COG0745	RESPONSE REGULATOR receiver
GFH33_RS02020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFH33_RS02030	COG0463	Glycosyl transferase, family 2
GFH33_RS02030	COG1216	Glycosyl transferase, family 2
GFH33_RS02055	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GFH33_RS02060	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GFH33_RS02065	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GFH33_RS02075	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GFH33_RS02090	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GFH33_RS02100	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GFH33_RS02110	COG0151	Belongs to the GarS family
GFH33_RS02135	COG0210	DNA helicase
GFH33_RS02145	COG4851	CamS sex pheromone cAM373 precursor
GFH33_RS02160	COG1335	isochorismatase
GFH33_RS02170	COG2011	ABC-type metal ion transport system permease component
GFH33_RS02175	COG1464	Belongs to the NlpA lipoprotein family
GFH33_RS02190	COG0003	Pfam Anion-transporting ATPase
GFH33_RS02195	COG1846	Transcriptional regulator
GFH33_RS02200	COG4682	membrane
GFH33_RS02220	COG1597	lipid kinase activity
GFH33_RS02230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GFH33_RS02240	COG1012	belongs to the aldehyde dehydrogenase family
GFH33_RS02245	COG2076	Multidrug Resistance protein
GFH33_RS02255	COG2309	aminopeptidase activity
GFH33_RS02270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GFH33_RS02280	COG0582	viral genome integration into host DNA
GFH33_RS02330	COG1484	DNA-dependent DNA replication
GFH33_RS02340	COG2002	toxin-antitoxin pair type II binding
GFH33_RS02450	COG0582	viral genome integration into host DNA
GFH33_RS02490	COG1802	Transcriptional regulator
GFH33_RS02490	COG4626	Terminase
GFH33_RS02500	COG3547	Transposase (IS116 IS110 IS902 family)
GFH33_RS02505	COG0740	serine-type endopeptidase activity
GFH33_RS02590	COG0730	response to heat
GFH33_RS02615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GFH33_RS02620	COG4807	Protein conserved in bacteria
GFH33_RS02650	COG1473	amidohydrolase
GFH33_RS02665	COG0450	alkyl hydroperoxide reductase
GFH33_RS02685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFH33_RS02690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFH33_RS02695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GFH33_RS02700	COG0492	ferredoxin-NADP+ reductase activity
GFH33_RS02710	COG0166	Belongs to the GPI family
GFH33_RS02735	COG5002	protein histidine kinase activity
GFH33_RS02755	COG3541	Predicted nucleotidyltransferase
GFH33_RS02760	COG2814	Major facilitator Superfamily
GFH33_RS02785	COG0765	amino acid transport
GFH33_RS02790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFH33_RS02800	COG0840	transmembrane signaling receptor activity
GFH33_RS02825	COG0549	Belongs to the carbamate kinase family
GFH33_RS02830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFH33_RS02860	COG0366	Alpha amylase catalytic
GFH33_RS02865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFH33_RS02865	COG1263	PTS System
GFH33_RS02865	COG2190	(PTS) system
GFH33_RS02895	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GFH33_RS02915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFH33_RS02925	COG1116	anion transmembrane transporter activity
GFH33_RS02975	COG2270	Major facilitator Superfamily
GFH33_RS03005	COG2310	stress, protein
GFH33_RS03010	COG2310	stress, protein
GFH33_RS03015	COG2310	stress, protein
GFH33_RS03020	COG0861	Integral membrane protein TerC family
GFH33_RS03030	COG3853	Toxic anion resistance protein (TelA)
GFH33_RS03045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GFH33_RS03055	COG1295	ribonuclease BN
GFH33_RS03060	COG2217	Heavy metal translocating P-type atpase
GFH33_RS03085	COG0586	Pfam SNARE associated Golgi protein
GFH33_RS03100	COG3871	stress protein (general stress protein 26)
GFH33_RS03105	COG0387	Pfam Sodium calcium exchanger
GFH33_RS03115	COG0535	radical SAM domain protein
GFH33_RS03135	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GFH33_RS03140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GFH33_RS03155	COG3829	transcription factor binding
GFH33_RS03165	COG0833	amino acid
GFH33_RS03170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFH33_RS03200	COG1263	PTS System
GFH33_RS03200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFH33_RS03205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GFH33_RS03220	COG0463	Glycosyl transferase, family 2
GFH33_RS03230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFH33_RS03230	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GFH33_RS03250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GFH33_RS03270	COG1228	amidohydrolase
GFH33_RS03275	COG1090	epimerase
GFH33_RS03305	COG1988	membrane-bound metal-dependent
GFH33_RS03310	COG1194	a g-specific adenine glycosylase
GFH33_RS03335	COG1132	(ABC) transporter
GFH33_RS03340	COG4129	membrane
GFH33_RS03345	COG0067	glutamate synthase
GFH33_RS03345	COG0069	glutamate synthase activity
GFH33_RS03345	COG0070	glutamate synthase
GFH33_RS03355	COG4555	ABC transporter
GFH33_RS03375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GFH33_RS03380	COG0735	belongs to the Fur family
GFH33_RS03500	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GFH33_RS03525	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GFH33_RS03530	COG1716	ATPase activity
GFH33_RS03530	COG5001	Diguanylate cyclase
GFH33_RS03535	COG2766	serine protein kinase
GFH33_RS03555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GFH33_RS03565	COG1585	Membrane protein implicated in regulation of membrane protease activity
GFH33_RS03570	COG2268	Band 7 protein
GFH33_RS03580	COG3290	protein histidine kinase activity
GFH33_RS03585	COG4565	transcriptional regulatory protein
GFH33_RS03590	COG2851	Citrate transporter
GFH33_RS03615	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GFH33_RS03620	COG3842	ATPase activity
GFH33_RS03625	COG1175	transmembrane transport
GFH33_RS03630	COG0395	ABC-type sugar transport system, permease component
GFH33_RS03640	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GFH33_RS03645	COG0745	RESPONSE REGULATOR receiver
GFH33_RS03650	COG5002	protein histidine kinase activity
GFH33_RS03650	COG3850	Histidine kinase
GFH33_RS03660	COG4990	cell redox homeostasis
GFH33_RS03670	COG3290	protein histidine kinase activity
GFH33_RS03675	COG4565	transcriptional regulatory protein
GFH33_RS03680	COG3493	citrate carrier protein
GFH33_RS03685	COG0281	malic enzyme
GFH33_RS03695	COG0697	spore germination
GFH33_RS03700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFH33_RS03710	COG5002	protein histidine kinase activity
GFH33_RS03715	COG0745	RESPONSE REGULATOR receiver
GFH33_RS03720	COG0454	-acetyltransferase
GFH33_RS03720	COG0456	acetyltransferase
GFH33_RS03725	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GFH33_RS03730	COG3383	formate dehydrogenase (NAD+) activity
GFH33_RS03735	COG2427	Protein of unknown function (DUF1641)
GFH33_RS03750	COG0531	amino acid
GFH33_RS03760	COG0640	Transcriptional regulator
GFH33_RS03765	COG2217	Heavy metal translocating P-type atpase
GFH33_RS03770	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GFH33_RS03785	COG3227	Zinc metalloprotease (Elastase)
GFH33_RS03805	COG2720	vancomycin resistance protein
GFH33_RS03810	COG1316	TRANSCRIPTIONal
GFH33_RS03815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GFH33_RS03825	COG3344	reverse transcriptase
GFH33_RS03835	COG0346	lactoylglutathione lyase activity
GFH33_RS03840	COG1253	flavin adenine dinucleotide binding
GFH33_RS03845	COG1027	Aspartate ammonia-lyase
GFH33_RS03850	COG1620	l-lactate permease
GFH33_RS03875	COG3104	oligopeptide transport
GFH33_RS03880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GFH33_RS03885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFH33_RS03890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFH33_RS03900	COG2226	methyltransferase
GFH33_RS03910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFH33_RS03920	COG4548	von Willebrand factor, type A
GFH33_RS03925	COG0714	Associated with various cellular activities
GFH33_RS03945	COG0531	amino acid
GFH33_RS03950	COG2188	Transcriptional regulator
GFH33_RS03955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFH33_RS03955	COG1263	PTS System
GFH33_RS03960	COG0366	Alpha amylase catalytic
GFH33_RS03975	COG0697	spore germination
GFH33_RS03980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GFH33_RS03985	COG1115	amino acid carrier protein
GFH33_RS03990	COG1126	abc transporter atp-binding protein
GFH33_RS03995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFH33_RS04000	COG0765	amino acid transport
GFH33_RS04005	COG0765	amino acid transport
GFH33_RS04010	COG0833	amino acid
GFH33_RS04025	COG1595	DNA-templated transcription, initiation
GFH33_RS04035	COG2378	regulation of single-species biofilm formation
GFH33_RS04040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GFH33_RS04045	COG5002	protein histidine kinase activity
GFH33_RS04075	COG2271	Major facilitator Superfamily
GFH33_RS04080	COG1846	Transcriptional regulator
GFH33_RS04085	COG0477	Major facilitator Superfamily
GFH33_RS04090	COG1609	Transcriptional regulator
GFH33_RS04095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFH33_RS04110	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFH33_RS04115	COG1879	ABC-type sugar transport system periplasmic component
GFH33_RS04145	COG1063	alcohol dehydrogenase
GFH33_RS04180	COG1396	sequence-specific DNA binding
GFH33_RS04265	COG0582	viral genome integration into host DNA
GFH33_RS04315	COG1802	Transcriptional regulator
GFH33_RS04315	COG4626	Terminase
GFH33_RS04325	COG0740	serine-type endopeptidase activity
GFH33_RS04420	COG1674	ftsk spoiiie
GFH33_RS04465	COG0840	transmembrane signaling receptor activity
GFH33_RS04470	COG3583	domain protein
GFH33_RS04470	COG3584	3D domain protein
GFH33_RS04475	COG1476	TRANSCRIPTIONal
GFH33_RS04495	COG3104	oligopeptide transport
GFH33_RS04500	COG1114	Component of the transport system for branched-chain amino acids
GFH33_RS04515	COG1113	amino acid transport
GFH33_RS04520	COG2252	PERMEase
GFH33_RS04535	COG2153	protein acetylation
GFH33_RS04545	COG0569	domain protein
GFH33_RS04545	COG0475	glutathione-regulated potassium exporter activity
GFH33_RS04555	COG1845	cytochrome c oxidase, subunit III
GFH33_RS04560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GFH33_RS04570	COG0833	amino acid
GFH33_RS04575	COG4990	cell redox homeostasis
GFH33_RS04590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GFH33_RS04595	COG0697	spore germination
GFH33_RS04600	COG0531	amino acid
GFH33_RS04615	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GFH33_RS04620	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GFH33_RS04625	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GFH33_RS04625	COG1918	ferrous iron import across plasma membrane
GFH33_RS04630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GFH33_RS04635	COG0573	inorganic phosphate transmembrane transporter activity
GFH33_RS04640	COG0581	inorganic phosphate transmembrane transporter activity
GFH33_RS04645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFH33_RS04765	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GFH33_RS04785	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GFH33_RS04790	COG1116	anion transmembrane transporter activity
GFH33_RS04795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFH33_RS04800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFH33_RS04805	COG0352	thiamine-phosphate diphosphorylase activity
GFH33_RS04810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFH33_RS04815	COG2104	thiamine diphosphate biosynthetic process
GFH33_RS04825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GFH33_RS04830	COG0351	phosphomethylpyrimidine kinase
GFH33_RS04870	COG2205	protein histidine kinase activity
GFH33_RS04875	COG2814	Major facilitator Superfamily
GFH33_RS04880	COG1846	Transcriptional regulator
GFH33_RS04905	COG1136	(ABC) transporter
GFH33_RS04915	COG2252	PERMEase
GFH33_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS04985	COG0778	Nitroreductase
GFH33_RS04990	COG2719	SpoVR family
GFH33_RS05000	COG3591	Belongs to the peptidase S1B family
GFH33_RS05010	COG0446	pyridine nucleotide-disulphide oxidoreductase
GFH33_RS05015	COG1937	Protein conserved in bacteria
GFH33_RS05020	COG0425	Belongs to the sulfur carrier protein TusA family
GFH33_RS05020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFH33_RS05025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFH33_RS05025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFH33_RS05030	COG0425	Belongs to the sulfur carrier protein TusA family
GFH33_RS05045	COG2210	Belongs to the sulfur carrier protein TusA family
GFH33_RS05050	COG0730	response to heat
GFH33_RS05060	COG1316	TRANSCRIPTIONal
GFH33_RS05065	COG0604	alcohol dehydrogenase
GFH33_RS05070	COG1283	sodium-dependent phosphate transmembrane transporter activity
GFH33_RS05085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFH33_RS05085	COG3711	transcriptional antiterminator
GFH33_RS05090	COG1447	Phosphotransferase system cellobiose-specific component IIA
GFH33_RS05095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFH33_RS05120	COG3584	3D domain protein
GFH33_RS05120	COG1388	LysM domain
GFH33_RS05125	COG0577	efflux transmembrane transporter activity
GFH33_RS05130	COG1136	(ABC) transporter
GFH33_RS05140	COG5522	Integral membrane protein (intg_mem_TP0381)
GFH33_RS05155	COG1114	Component of the transport system for branched-chain amino acids
GFH33_RS05160	COG3546	catalase activity
GFH33_RS05195	COG0586	Pfam SNARE associated Golgi protein
GFH33_RS05230	COG0531	amino acid
GFH33_RS05235	COG0475	glutathione-regulated potassium exporter activity
GFH33_RS05245	COG1737	Transcriptional regulator
GFH33_RS05255	COG1263	PTS System
GFH33_RS05255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFH33_RS05265	COG2259	Doxx family
GFH33_RS05285	COG1522	sequence-specific DNA binding
GFH33_RS05290	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GFH33_RS05290	COG0165	Argininosuccinate lyase
GFH33_RS05295	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS05315	COG1309	transcriptional regulator
GFH33_RS05320	COG2814	Major facilitator Superfamily
GFH33_RS05325	COG1733	regulation of RNA biosynthetic process
GFH33_RS05340	COG4533	DNA binding
GFH33_RS05345	COG2211	Major facilitator Superfamily
GFH33_RS05360	COG0693	protein deglycase activity
GFH33_RS05365	COG0753	catalase activity
GFH33_RS05375	COG0531	amino acid
GFH33_RS05390	COG1012	belongs to the aldehyde dehydrogenase family
GFH33_RS05395	COG1132	(ABC) transporter
GFH33_RS05400	COG1132	(ABC) transporter
GFH33_RS05405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFH33_RS05410	COG0765	amino acid transport
GFH33_RS05415	COG1126	abc transporter atp-binding protein
GFH33_RS05430	COG0189	ligase activity
GFH33_RS05460	COG0028	Belongs to the TPP enzyme family
GFH33_RS05465	COG3527	Alpha-acetolactate decarboxylase
GFH33_RS05480	COG0561	phosphatase activity
GFH33_RS05490	COG5632	N-Acetylmuramoyl-L-alanine amidase
GFH33_RS05490	COG3409	Peptidoglycan-binding domain 1 protein
GFH33_RS05495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GFH33_RS05500	COG0318	PFAM AMP-dependent synthetase and ligase
GFH33_RS05515	COG0659	secondary active sulfate transmembrane transporter activity
GFH33_RS05520	COG2244	polysaccharide biosynthetic process
GFH33_RS05540	COG1024	Enoyl-CoA hydratase
GFH33_RS05560	COG1363	Peptidase, m42
GFH33_RS05600	COG0601	transmembrane transport
GFH33_RS05605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFH33_RS05610	COG0444	Belongs to the ABC transporter superfamily
GFH33_RS05615	COG4608	Belongs to the ABC transporter superfamily
GFH33_RS05635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFH33_RS05740	COG0477	Major facilitator Superfamily
GFH33_RS05745	COG3290	protein histidine kinase activity
GFH33_RS05750	COG4565	transcriptional regulatory protein
GFH33_RS05755	COG3181	Tripartite tricarboxylate transporter family receptor
GFH33_RS05760	COG0494	nUDIX hydrolase
GFH33_RS05775	COG0305	Participates in initiation and elongation during chromosome replication
GFH33_RS05790	COG0305	Participates in initiation and elongation during chromosome replication
GFH33_RS05815	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GFH33_RS05820	COG1288	antiporter activity
GFH33_RS05830	COG1842	Phage shock protein A
GFH33_RS05840	COG0477	Major facilitator Superfamily
GFH33_RS05860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS05910	COG2020	methyltransferase activity
GFH33_RS05930	COG3344	reverse transcriptase
GFH33_RS05950	COG1073	alpha beta
GFH33_RS05985	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GFH33_RS05990	COG1522	sequence-specific DNA binding
GFH33_RS06005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GFH33_RS06060	COG1183	phosphatidylcholine synthase activity
GFH33_RS06080	COG2814	Major facilitator Superfamily
GFH33_RS06085	COG0640	Transcriptional regulator
GFH33_RS06110	COG2376	Dihydroxyacetone kinase
GFH33_RS06120	COG2376	Dihydroxyacetone kinase
GFH33_RS06160	COG2373	Large extracellular alpha-helical protein
GFH33_RS06235	COG1191	sigma factor activity
GFH33_RS06245	COG2208	phosphoserine phosphatase activity
GFH33_RS06250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GFH33_RS06255	COG0784	Response regulator, receiver
GFH33_RS06255	COG2205	protein histidine kinase activity
GFH33_RS06255	COG5002	protein histidine kinase activity
GFH33_RS06300	COG2186	Transcriptional regulator
GFH33_RS06310	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GFH33_RS06330	COG0420	3'-5' exonuclease activity
GFH33_RS06335	COG4717	serine-type aminopeptidase activity
GFH33_RS06360	COG0346	lactoylglutathione lyase activity
GFH33_RS06365	COG0346	lactoylglutathione lyase activity
GFH33_RS06370	COG0457	Tetratricopeptide repeat
GFH33_RS06400	COG2140	Oxalate decarboxylase
GFH33_RS06410	COG3620	sequence-specific DNA binding
GFH33_RS06415	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GFH33_RS06420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GFH33_RS06430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GFH33_RS06445	COG1595	DNA-templated transcription, initiation
GFH33_RS06455	COG0772	Belongs to the SEDS family
GFH33_RS06460	COG3973	AAA domain
GFH33_RS06485	COG4980	gas vesicle protein
GFH33_RS06490	COG0537	adenosine 5'-monophosphoramidase activity
GFH33_RS06495	COG1131	(ABC) transporter
GFH33_RS06500	COG4473	ABC transporter
GFH33_RS06515	COG1309	transcriptional regulator
GFH33_RS06525	COG3402	PFAM membrane-flanked domain
GFH33_RS06530	COG3428	Bacterial PH domain
GFH33_RS06565	COG0697	spore germination
GFH33_RS06570	COG3402	PFAM membrane-flanked domain
GFH33_RS06575	COG3428	Bacterial PH domain
GFH33_RS06580	COG2329	Antibiotic biosynthesis monooxygenase
GFH33_RS06585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFH33_RS06600	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GFH33_RS06635	COG1309	transcriptional regulator
GFH33_RS06640	COG1511	domain protein
GFH33_RS06640	COG1511	domain protein
GFH33_RS06670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS06675	COG1609	Transcriptional regulator
GFH33_RS06685	COG1234	tRNA 3'-trailer cleavage
GFH33_RS06690	COG0095	Lipoate-protein ligase
GFH33_RS06700	COG0318	PFAM AMP-dependent synthetase and ligase
GFH33_RS06710	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GFH33_RS06720	COG4208	sulfate ABC transporter
GFH33_RS06810	COG1073	alpha beta
GFH33_RS06820	COG1078	dGTPase activity
GFH33_RS06830	COG1595	DNA-templated transcription, initiation
GFH33_RS06835	COG2207	Transcriptional regulator
GFH33_RS06835	COG3708	Transcriptional regulator
GFH33_RS06850	COG0745	RESPONSE REGULATOR receiver
GFH33_RS06870	COG0501	Belongs to the peptidase M48B family
GFH33_RS06875	COG0840	transmembrane signaling receptor activity
GFH33_RS06880	COG3693	PFAM glycoside hydrolase, family 10
GFH33_RS06890	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GFH33_RS06895	COG2224	Isocitrate lyase
GFH33_RS06910	COG1278	Cold shock
GFH33_RS06930	COG0398	Pfam SNARE associated Golgi protein
GFH33_RS06990	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFH33_RS07015	COG0367	asparagine synthase
GFH33_RS07030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GFH33_RS07130	COG3331	DNA recombination
GFH33_RS07155	COG3547	Transposase (IS116 IS110 IS902 family)
GFH33_RS07190	COG3547	Transposase (IS116 IS110 IS902 family)
GFH33_RS07260	COG4824	toxin secretion phage lysis holin
GFH33_RS07265	COG1388	LysM domain
GFH33_RS07265	COG3409	Peptidoglycan-binding domain 1 protein
GFH33_RS07265	COG5632	N-Acetylmuramoyl-L-alanine amidase
GFH33_RS07295	COG0753	catalase activity
GFH33_RS07305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GFH33_RS07330	COG3339	Conserved Protein
GFH33_RS07335	COG0004	ammonium transporteR
GFH33_RS07355	COG2996	Protein conserved in bacteria
GFH33_RS07380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFH33_RS07395	COG0561	phosphatase activity
GFH33_RS07415	COG2267	carboxylic ester hydrolase activity
GFH33_RS07430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GFH33_RS07435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GFH33_RS07440	COG5504	Zn-dependent protease
GFH33_RS07450	COG0180	Tryptophanyl-tRNA synthetase
GFH33_RS07460	COG4166	transmembrane transport
GFH33_RS07465	COG0601	transmembrane transport
GFH33_RS07470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFH33_RS07475	COG0444	Belongs to the ABC transporter superfamily
GFH33_RS07480	COG4608	Belongs to the ABC transporter superfamily
GFH33_RS07485	COG0534	Mate efflux family protein
GFH33_RS07490	COG4166	transmembrane transport
GFH33_RS07505	COG0861	Integral membrane protein TerC family
GFH33_RS07515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFH33_RS07525	COG1164	Oligoendopeptidase f
GFH33_RS07540	COG2346	COG2346, Truncated hemoglobins
GFH33_RS07545	COG4116	CYTH
GFH33_RS07555	COG2357	RelA SpoT domain protein
GFH33_RS07565	COG0564	pseudouridine synthase activity
GFH33_RS07580	COG0772	Belongs to the SEDS family
GFH33_RS07585	COG1216	Glycosyl transferase, family 2
GFH33_RS07605	COG0457	Tetratricopeptide repeat
GFH33_RS07605	COG0463	Glycosyl transferase, family 2
GFH33_RS07625	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GFH33_RS07640	COG1091	dTDP-4-dehydrorhamnose reductase activity
GFH33_RS07685	COG2153	protein acetylation
GFH33_RS07695	COG2382	esterase
GFH33_RS07720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GFH33_RS07730	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GFH33_RS07730	COG0512	Glutamine amidotransferase of anthranilate synthase
GFH33_RS07765	COG1620	l-lactate permease
GFH33_RS07770	COG5634	Uncharacterized conserved protein (DUF2278)
GFH33_RS07815	COG2226	methyltransferase
GFH33_RS07835	COG0508	dehydrogenase complex catalyzes the overall conversion of
GFH33_RS07845	COG1476	TRANSCRIPTIONal
GFH33_RS07890	COG4152	abc transporter atp-binding protein
GFH33_RS07895	COG1668	transmembrane transport
GFH33_RS07915	COG2226	methyltransferase
GFH33_RS07925	COG1686	Belongs to the peptidase S11 family
GFH33_RS07930	COG0681	Belongs to the peptidase S26 family
GFH33_RS07965	COG1012	belongs to the aldehyde dehydrogenase family
GFH33_RS07975	COG1176	ABC-type spermidine putrescine transport system, permease component I
GFH33_RS07980	COG1177	transmembrane transport
GFH33_RS07995	COG2409	Drug exporters of the RND superfamily
GFH33_RS08005	COG0564	pseudouridine synthase activity
GFH33_RS08015	COG2340	Cysteine-rich secretory protein family
GFH33_RS08020	COG0247	lactate metabolic process
GFH33_RS08025	COG0277	FAD linked oxidase domain protein
GFH33_RS08030	COG3835	regulator
GFH33_RS08040	COG0745	RESPONSE REGULATOR receiver
GFH33_RS08045	COG5002	protein histidine kinase activity
GFH33_RS08050	COG2186	Transcriptional regulator
GFH33_RS08070	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GFH33_RS08080	COG2116	formate transmembrane transporter activity
GFH33_RS08085	COG0861	Integral membrane protein TerC family
GFH33_RS08090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GFH33_RS08100	COG2030	dehydratase
GFH33_RS08120	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS08125	COG3243	poly(R)-hydroxyalkanoic acid synthase
GFH33_RS08135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GFH33_RS08150	COG1840	ABC-type Fe3 transport system, periplasmic component
GFH33_RS08155	COG3842	ATPase activity
GFH33_RS08180	COG1349	DNA-binding transcription factor activity
GFH33_RS08190	COG0235	Class ii aldolase
GFH33_RS08200	COG2861	carbohydrate metabolic process
GFH33_RS08210	COG3852	Histidine kinase
GFH33_RS08215	COG1846	Transcriptional regulator
GFH33_RS08225	COG2318	DinB family
GFH33_RS08235	COG5002	protein histidine kinase activity
GFH33_RS08245	COG0720	synthase
GFH33_RS08260	COG4873	Protein conserved in bacteria
GFH33_RS08290	COG1780	Probably involved in ribonucleotide reductase function
GFH33_RS08295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFH33_RS08310	COG1725	Transcriptional regulator
GFH33_RS08315	COG1131	(ABC) transporter
GFH33_RS08325	COG1131	(ABC) transporter
GFH33_RS08345	COG1522	sequence-specific DNA binding
GFH33_RS08355	COG1335	isochorismatase
GFH33_RS08365	COG1619	proteins homologs of microcin C7 resistance protein MccF
GFH33_RS08370	COG2070	2-Nitropropane dioxygenase
GFH33_RS08375	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GFH33_RS08385	COG1696	Membrane protein involved in D-alanine export
GFH33_RS08410	COG0716	FMN binding
GFH33_RS08460	COG1846	Transcriptional regulator
GFH33_RS08470	COG1301	dicarboxylic acid transport
GFH33_RS08475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GFH33_RS08480	COG4709	membrane
GFH33_RS08485	COG3874	Sporulation protein YtfJ
GFH33_RS08505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GFH33_RS08510	COG0028	Belongs to the TPP enzyme family
GFH33_RS08515	COG0440	acetolactate synthase activity
GFH33_RS08590	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GFH33_RS08605	COG1183	phosphatidylcholine synthase activity
GFH33_RS08610	COG1368	sulfuric ester hydrolase activity
GFH33_RS08620	COG0019	diaminopimelate decarboxylase activity
GFH33_RS08640	COG0529	Catalyzes the synthesis of activated sulfate
GFH33_RS08645	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GFH33_RS08665	COG1648	precorrin-2 dehydrogenase activity
GFH33_RS08670	COG0733	neurotransmitter:sodium symporter activity
GFH33_RS08695	COG1757	Na H antiporter
GFH33_RS08710	COG4758	membrane
GFH33_RS08715	COG4585	Histidine kinase
GFH33_RS08720	COG2197	response regulator
GFH33_RS08730	COG1114	Component of the transport system for branched-chain amino acids
GFH33_RS08780	COG0730	response to heat
GFH33_RS08785	COG0306	phosphate transporter
GFH33_RS08790	COG1392	Phosphate transport regulator
GFH33_RS08795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFH33_RS08810	COG3852	Histidine kinase
GFH33_RS08815	COG1801	Protein of unknown function DUF72
GFH33_RS08825	COG0582	viral genome integration into host DNA
GFH33_RS08830	COG5002	protein histidine kinase activity
GFH33_RS08845	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GFH33_RS08845	COG0392	lysyltransferase activity
GFH33_RS08860	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GFH33_RS08865	COG1686	Belongs to the peptidase S11 family
GFH33_RS08870	COG2715	membrane protein required for spore maturation
GFH33_RS08875	COG0700	Nucleoside recognition
GFH33_RS08880	COG1187	pseudouridine synthase activity
GFH33_RS08890	COG1333	cytochrome c biogenesis protein
GFH33_RS08895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GFH33_RS08900	COG0745	RESPONSE REGULATOR receiver
GFH33_RS08905	COG5002	protein histidine kinase activity
GFH33_RS08910	COG2096	Adenosyltransferase
GFH33_RS08925	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GFH33_RS08930	COG1141	Ferredoxin
GFH33_RS08940	COG0514	ATP-dependent DNA helicase (RecQ)
GFH33_RS08945	COG1266	CAAX protease self-immunity
GFH33_RS08955	COG1408	metallophosphoesterase
GFH33_RS08960	COG0789	Transcriptional regulator
GFH33_RS08970	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GFH33_RS08990	COG0492	ferredoxin-NADP+ reductase activity
GFH33_RS08995	COG0252	asparaginase activity
GFH33_RS09065	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GFH33_RS09080	COG0142	geranyltranstransferase activity
GFH33_RS09090	COG0142	geranyltranstransferase activity
GFH33_RS09120	COG0457	Tetratricopeptide repeat
GFH33_RS09140	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GFH33_RS09145	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GFH33_RS09145	COG2010	Cytochrome c
GFH33_RS09150	COG4347	Protein of unknown function (DUF1405)
GFH33_RS09165	COG2738	Putative neutral zinc metallopeptidase
GFH33_RS09180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFH33_RS09185	COG1694	Mazg nucleotide pyrophosphohydrolase
GFH33_RS09205	COG0438	transferase activity, transferring glycosyl groups
GFH33_RS09240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GFH33_RS09240	COG1199	ATP-dependent helicase activity
GFH33_RS09260	COG3935	DnaD domain protein
GFH33_RS09265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GFH33_RS09275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFH33_RS09275	COG4499	WXG100 protein secretion system (Wss), protein YukC
GFH33_RS09330	COG0116	Belongs to the methyltransferase superfamily
GFH33_RS09340	COG1199	ATP-dependent helicase activity
GFH33_RS09345	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GFH33_RS09355	COG0024	Methionine aminopeptidase
GFH33_RS09365	COG2233	PERMEase
GFH33_RS09370	COG2311	Membrane
GFH33_RS09380	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GFH33_RS09390	COG0456	acetyltransferase
GFH33_RS09440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFH33_RS09455	COG3944	biosynthesis protein
GFH33_RS09465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GFH33_RS09480	COG1215	transferase activity, transferring glycosyl groups
GFH33_RS09485	COG0438	transferase activity, transferring glycosyl groups
GFH33_RS09500	COG0454	-acetyltransferase
GFH33_RS09520	COG0328	RNA-DNA hybrid ribonuclease activity
GFH33_RS09555	COG3403	YqcI/YcgG family
GFH33_RS09560	COG1280	lysine exporter protein (LysE YggA)
GFH33_RS09580	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GFH33_RS09585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GFH33_RS09595	COG0475	glutathione-regulated potassium exporter activity
GFH33_RS09600	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GFH33_RS09605	COG0789	Transcriptional regulator
GFH33_RS09605	COG4978	Transcriptional regulator
GFH33_RS09615	COG2323	membrane
GFH33_RS09620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GFH33_RS09660	COG1923	regulation of RNA biosynthetic process
GFH33_RS09670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GFH33_RS09675	COG1360	Flagellar Motor Protein
GFH33_RS09680	COG2201	protein-glutamate methylesterase activity
GFH33_RS09685	COG2198	Histidine kinase
GFH33_RS09685	COG0643	Histidine kinase
GFH33_RS09690	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GFH33_RS09690	COG1776	CheC inhibitor of MCP methylation
GFH33_RS09705	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GFH33_RS09725	COG1256	bacterial-type flagellum assembly
GFH33_RS09730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GFH33_RS09750	COG1815	bacterial-type flagellum-dependent cell motility
GFH33_RS09755	COG1558	bacterial-type flagellum-dependent cell motility
GFH33_RS09765	COG1766	The M ring may be actively involved in energy transduction
GFH33_RS09770	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GFH33_RS09780	COG1157	protein secretion by the type III secretion system
GFH33_RS09815	COG0835	chemotaxis
GFH33_RS09815	COG0784	Response regulator, receiver
GFH33_RS09825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GFH33_RS09830	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GFH33_RS09835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GFH33_RS09840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GFH33_RS09845	COG0741	lytic transglycosylase activity
GFH33_RS09855	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GFH33_RS09860	COG1776	CheC inhibitor of MCP methylation
GFH33_RS09860	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GFH33_RS09870	COG1338	Plays a role in the flagellum-specific transport system
GFH33_RS09875	COG1987	bacterial-type flagellum assembly
GFH33_RS09885	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GFH33_RS09890	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GFH33_RS09895	COG1419	protein localization to endoplasmic reticulum
GFH33_RS09900	COG4786	Flagellar basal body rod
GFH33_RS09905	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GFH33_RS09965	COG0583	DNA-binding transcription factor activity
GFH33_RS09970	COG3842	ATPase activity
GFH33_RS09975	COG0725	ABC transporter, periplasmic molybdate-binding protein
GFH33_RS10015	COG0406	alpha-ribazole phosphatase activity
GFH33_RS10030	COG3547	Transposase (IS116 IS110 IS902 family)
GFH33_RS10055	COG0367	asparagine synthase
GFH33_RS10085	COG1802	Transcriptional regulator
GFH33_RS10090	COG0697	spore germination
GFH33_RS10100	COG0523	cobalamin synthesis protein
GFH33_RS10105	COG0701	Predicted permease
GFH33_RS10120	COG1757	Na H antiporter
GFH33_RS10125	COG0789	Transcriptional regulator
GFH33_RS10150	COG0534	Mate efflux family protein
GFH33_RS10155	COG3340	Belongs to the peptidase S51 family
GFH33_RS10175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFH33_RS10195	COG2733	membrane
GFH33_RS10230	COG1131	(ABC) transporter
GFH33_RS10250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFH33_RS10255	COG0528	UMP kinase activity
GFH33_RS10270	COG1027	Aspartate ammonia-lyase
GFH33_RS10275	COG0281	malic enzyme
GFH33_RS10280	COG4191	Histidine kinase
GFH33_RS10285	COG0784	Response regulator, receiver
GFH33_RS10290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GFH33_RS10310	COG3620	sequence-specific DNA binding
GFH33_RS10345	COG2814	Major facilitator Superfamily
GFH33_RS10360	COG1695	Transcriptional regulator
GFH33_RS10370	COG0477	Major facilitator Superfamily
GFH33_RS10380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GFH33_RS10385	COG2223	nitrite transmembrane transporter activity
GFH33_RS10390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GFH33_RS10410	COG0733	neurotransmitter:sodium symporter activity
GFH33_RS10415	COG5566	PFAM Mor transcription activator
GFH33_RS10420	COG2323	membrane
GFH33_RS10440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFH33_RS10450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GFH33_RS10455	COG0028	Belongs to the TPP enzyme family
GFH33_RS10475	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GFH33_RS10500	COG2814	Major facilitator Superfamily
GFH33_RS10505	COG3384	dioxygenase
GFH33_RS10515	COG3279	Response regulator of the LytR AlgR family
GFH33_RS10520	COG0427	acetyl-CoA hydrolase
GFH33_RS10540	COG4166	transmembrane transport
GFH33_RS10545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS10550	COG1914	H( )-stimulated, divalent metal cation uptake system
GFH33_RS10565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GFH33_RS10570	COG0531	amino acid
GFH33_RS10605	COG1309	transcriptional regulator
GFH33_RS10610	COG2390	Transcriptional regulator
GFH33_RS10620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GFH33_RS10625	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GFH33_RS10640	COG4846	Membrane protein involved in cytochrome C biogenesis
GFH33_RS10650	COG0006	proline dipeptidase activity
GFH33_RS10660	COG2132	Multicopper oxidase
GFH33_RS10670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GFH33_RS10690	COG1114	Component of the transport system for branched-chain amino acids
GFH33_RS10700	COG2372	response to copper ion
GFH33_RS10700	COG1276	copper resistance
GFH33_RS10705	COG4549	nuclear export factor GLE1
GFH33_RS10710	COG0697	spore germination
GFH33_RS10715	COG0583	DNA-binding transcription factor activity
GFH33_RS10720	COG1959	2 iron, 2 sulfur cluster binding
GFH33_RS10725	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GFH33_RS10730	COG0778	Nitroreductase
GFH33_RS10740	COG0628	permease
GFH33_RS10750	COG1231	oxidoreductase activity
GFH33_RS10755	COG0523	cobalamin synthesis protein
GFH33_RS10765	COG0411	ABC transporter
GFH33_RS10785	COG0583	DNA-binding transcription factor activity
GFH33_RS10815	COG1271	oxidase subunit
GFH33_RS10820	COG1294	oxidase, subunit
GFH33_RS10825	COG4988	ABC transporter
GFH33_RS10830	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GFH33_RS10840	COG1216	Glycosyl transferase, family 2
GFH33_RS10880	COG1686	Belongs to the peptidase S11 family
GFH33_RS10895	COG1388	LysM domain
GFH33_RS10895	COG0791	NLP P60 protein
GFH33_RS10905	COG1132	(ABC) transporter
GFH33_RS10910	COG0745	RESPONSE REGULATOR receiver
GFH33_RS10915	COG5002	protein histidine kinase activity
GFH33_RS10920	COG0300	oxidoreductase activity
GFH33_RS10950	COG3547	Transposase (IS116 IS110 IS902 family)
GFH33_RS10955	COG0460	homoserine dehydrogenase
GFH33_RS10980	COG1316	TRANSCRIPTIONal
GFH33_RS10990	COG0745	RESPONSE REGULATOR receiver
GFH33_RS10995	COG5002	protein histidine kinase activity
GFH33_RS11010	COG1285	pathogenesis
GFH33_RS11015	COG1247	-acetyltransferase
GFH33_RS11055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFH33_RS11065	COG1082	Xylose isomerase domain protein TIM barrel
GFH33_RS11075	COG2814	Major facilitator Superfamily
GFH33_RS11080	COG1279	arginine transmembrane transporter activity
GFH33_RS11085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFH33_RS11095	COG1752	Esterase of the alpha-beta hydrolase superfamily
GFH33_RS11130	COG0577	efflux transmembrane transporter activity
GFH33_RS11135	COG2002	toxin-antitoxin pair type II binding
GFH33_RS11140	COG1404	Belongs to the peptidase S8 family
GFH33_RS11145	COG0640	Transcriptional regulator
GFH33_RS11150	COG0667	Aldo Keto reductase
GFH33_RS11155	COG2814	Major facilitator Superfamily
GFH33_RS11160	COG3152	Membrane
GFH33_RS11185	COG0840	transmembrane signaling receptor activity
GFH33_RS11200	COG3949	Membrane
GFH33_RS11205	COG0783	Belongs to the Dps family
GFH33_RS11225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFH33_RS11235	COG1231	oxidoreductase activity
GFH33_RS11240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS11245	COG4989	oxidoreductase activity
GFH33_RS11255	COG0523	cobalamin synthesis protein
GFH33_RS11260	COG0456	acetyltransferase
GFH33_RS11265	COG0803	Belongs to the bacterial solute-binding protein 9 family
GFH33_RS11280	COG3344	reverse transcriptase
GFH33_RS11290	COG0702	epimerase
GFH33_RS11300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GFH33_RS11310	COG4166	transmembrane transport
GFH33_RS11335	COG5337	Spore coat protein CotH
GFH33_RS11340	COG1051	belongs to the nudix hydrolase family
GFH33_RS11345	COG0586	Pfam SNARE associated Golgi protein
GFH33_RS11350	COG2244	polysaccharide biosynthetic process
GFH33_RS11360	COG0701	Predicted permease
GFH33_RS11365	COG3689	TIGRFAM TIGR03943 family protein
GFH33_RS11370	COG1607	acyl-coa hydrolase
GFH33_RS11380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFH33_RS11395	COG0702	epimerase
GFH33_RS11400	COG2839	Protein conserved in bacteria
GFH33_RS11405	COG1253	flavin adenine dinucleotide binding
GFH33_RS11425	COG1114	Component of the transport system for branched-chain amino acids
GFH33_RS11430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFH33_RS11450	COG0860	N-Acetylmuramoyl-L-alanine amidase
GFH33_RS11460	COG1876	peptidase activity
GFH33_RS11475	COG2211	Major facilitator Superfamily
GFH33_RS11490	COG0860	N-Acetylmuramoyl-L-alanine amidase
GFH33_RS11540	COG3646	Phage regulatory protein
GFH33_RS11610	COG0582	viral genome integration into host DNA
GFH33_RS11660	COG4626	Terminase
GFH33_RS11660	COG1802	Transcriptional regulator
GFH33_RS11670	COG0740	serine-type endopeptidase activity
GFH33_RS11715	COG3344	reverse transcriptase
GFH33_RS11750	COG3547	Transposase (IS116 IS110 IS902 family)
GFH33_RS11815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GFH33_RS11835	COG1819	glycosyl
GFH33_RS11840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFH33_RS11845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFH33_RS11875	COG0456	acetyltransferase
GFH33_RS11910	COG4499	WXG100 protein secretion system (Wss), protein YukC
GFH33_RS12010	COG3874	Sporulation protein YtfJ
GFH33_RS12035	COG2226	methyltransferase
GFH33_RS12055	COG1082	Xylose isomerase domain protein TIM barrel
GFH33_RS12060	COG0346	lactoylglutathione lyase activity
GFH33_RS12070	COG0604	alcohol dehydrogenase
GFH33_RS12080	COG1595	DNA-templated transcription, initiation
GFH33_RS12095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFH33_RS12095	COG0426	domain, Protein
GFH33_RS12110	COG0386	Belongs to the glutathione peroxidase family
GFH33_RS12115	COG1305	Transglutaminase-like
GFH33_RS12120	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GFH33_RS12125	COG0714	Associated with various cellular activities
GFH33_RS12135	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GFH33_RS12140	COG1140	nitrate reductase beta subunit
GFH33_RS12145	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GFH33_RS12150	COG2181	nitrate reductase activity
GFH33_RS12155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFH33_RS12160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GFH33_RS12165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GFH33_RS12170	COG0303	'Molybdopterin
GFH33_RS12175	COG0314	molybdopterin synthase activity
GFH33_RS12180	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GFH33_RS12185	COG2223	nitrite transmembrane transporter activity
GFH33_RS12195	COG1648	precorrin-2 dehydrogenase activity
GFH33_RS12205	COG1587	Uroporphyrinogen-III synthase
GFH33_RS12205	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GFH33_RS12210	COG2146	nitrite reductase [NAD(P)H] activity
GFH33_RS12215	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GFH33_RS12220	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GFH33_RS12255	COG2359	stage V sporulation protein S
GFH33_RS12280	COG0730	response to heat
GFH33_RS12305	COG0457	Tetratricopeptide repeat
GFH33_RS12320	COG1418	mRNA catabolic process
GFH33_RS12325	COG0488	(ABC) transporter
GFH33_RS12435	COG0629	single-stranded DNA binding
GFH33_RS12445	COG1413	lyase activity
GFH33_RS12460	COG2136	Putative SAM-dependent methyltransferase
GFH33_RS12460	COG2521	methyltransferase
GFH33_RS12465	COG0018	arginyl-trna synthetase
GFH33_RS12520	COG0017	Asparaginyl-tRNA synthetase
GFH33_RS12525	COG0733	neurotransmitter:sodium symporter activity
GFH33_RS12550	COG2610	gluconate transmembrane transporter activity
GFH33_RS12560	COG1794	racemase activity, acting on amino acids and derivatives
GFH33_RS12570	COG0456	acetyltransferase
GFH33_RS12580	COG3655	Transcriptional regulator
GFH33_RS12585	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GFH33_RS12595	COG1131	(ABC) transporter
GFH33_RS12600	COG4473	ABC transporter
GFH33_RS12610	COG0546	phosphoglycolate phosphatase activity
GFH33_RS12625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GFH33_RS12640	COG0768	penicillin binding
GFH33_RS12650	COG0204	Acyl-transferase
GFH33_RS12655	COG1272	protein, Hemolysin III
GFH33_RS12665	COG0805	protein transport
GFH33_RS12675	COG1307	EDD domain protein, DegV family
GFH33_RS12685	COG1999	signal sequence binding
GFH33_RS12690	COG0071	Belongs to the small heat shock protein (HSP20) family
GFH33_RS12695	COG0367	asparagine synthase
GFH33_RS12715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GFH33_RS12720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GFH33_RS12740	COG1335	isochorismatase
GFH33_RS12755	COG0668	transmembrane transport
GFH33_RS12760	COG2203	Gaf domain
GFH33_RS12760	COG4585	Histidine kinase
GFH33_RS12765	COG2197	response regulator
GFH33_RS12770	COG1737	Transcriptional regulator
GFH33_RS12775	COG0384	phenazine biosynthesis protein PhzF
GFH33_RS12780	COG1064	alcohol dehydrogenase
GFH33_RS12805	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GFH33_RS12840	COG1125	glycine betaine transport
GFH33_RS12840	COG0517	IMP dehydrogenase activity
GFH33_RS12845	COG1174	glycine betaine transport
GFH33_RS12880	COG1253	flavin adenine dinucleotide binding
GFH33_RS12885	COG1012	belongs to the aldehyde dehydrogenase family
GFH33_RS12890	COG5506	Protein of unknown function (DUF1694)
GFH33_RS12905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GFH33_RS12910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GFH33_RS12915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GFH33_RS12920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFH33_RS12925	COG0456	acetyltransferase
GFH33_RS12930	COG3829	transcription factor binding
GFH33_RS12935	COG1509	lysine 2,3-aminomutase activity
GFH33_RS12970	COG4991	sh3 domain protein
GFH33_RS12970	COG3064	Membrane
GFH33_RS12970	COG0515	serine threonine protein kinase
GFH33_RS12980	COG0671	phosphoesterase, PA-phosphatase related
GFH33_RS12985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GFH33_RS12990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFH33_RS13075	COG0300	oxidoreductase activity
GFH33_RS13095	COG4499	WXG100 protein secretion system (Wss), protein YukC
GFH33_RS13095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFH33_RS13105	COG2814	Major facilitator Superfamily
GFH33_RS13110	COG4841	protein insertion into membrane
GFH33_RS13115	COG0372	Belongs to the citrate synthase family
GFH33_RS13120	COG2079	MmgE PrpD family protein
GFH33_RS13125	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GFH33_RS13130	COG1960	acyl-CoA dehydrogenase activity
GFH33_RS13135	COG2084	Dehydrogenase
GFH33_RS13145	COG1280	lysine exporter protein (LysE YggA)
GFH33_RS13150	COG1024	Enoyl-CoA hydratase
GFH33_RS13165	COG0420	3'-5' exonuclease activity
GFH33_RS13170	COG0419	ATPase involved in DNA repair
GFH33_RS13190	COG2223	nitrite transmembrane transporter activity
GFH33_RS13195	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS13200	COG1169	isochorismate synthase
GFH33_RS13205	COG1021	2,3-dihydroxybenzoate-AMP ligase
GFH33_RS13210	COG1535	isochorismatase
GFH33_RS13210	COG3433	isochorismatase activity
GFH33_RS13215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GFH33_RS13220	COG3251	PFAM MbtH domain protein
GFH33_RS13225	COG2814	Major facilitator Superfamily
GFH33_RS13240	COG0776	regulation of translation
GFH33_RS13250	COG2318	DinB family
GFH33_RS13260	COG1115	amino acid carrier protein
GFH33_RS13275	COG2329	Antibiotic biosynthesis monooxygenase
GFH33_RS13280	COG1187	pseudouridine synthase activity
GFH33_RS13285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GFH33_RS13290	COG1136	(ABC) transporter
GFH33_RS13305	COG0028	Belongs to the TPP enzyme family
GFH33_RS13345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFH33_RS13370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFH33_RS13405	COG1247	-acetyltransferase
GFH33_RS13430	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GFH33_RS13440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS13470	COG0583	DNA-binding transcription factor activity
GFH33_RS13475	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GFH33_RS13495	COG0583	DNA-binding transcription factor activity
GFH33_RS13500	COG2258	MOSC domain
GFH33_RS13515	COG1132	(ABC) transporter
GFH33_RS13520	COG1132	(ABC) transporter
GFH33_RS13545	COG1396	sequence-specific DNA binding
GFH33_RS13585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFH33_RS13590	COG1595	DNA-templated transcription, initiation
GFH33_RS13615	COG1649	PFAM Uncharacterised BCR, COG1649
GFH33_RS13640	COG2971	BadF BadG BcrA BcrD
GFH33_RS13660	COG1846	Transcriptional regulator
GFH33_RS13680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFH33_RS13700	COG1309	transcriptional regulator
GFH33_RS13720	COG3615	Tellurite resistance protein tehB
GFH33_RS13720	COG0500	methyltransferase
GFH33_RS13730	COG2226	methyltransferase
GFH33_RS13735	COG3961	Belongs to the TPP enzyme family
GFH33_RS13740	COG1846	Transcriptional regulator
GFH33_RS13770	COG2195	Cleaves the N-terminal amino acid of tripeptides
GFH33_RS13795	COG2002	toxin-antitoxin pair type II binding
GFH33_RS13810	COG0730	response to heat
GFH33_RS13815	COG0110	maltose O-acetyltransferase activity
GFH33_RS13820	COG1686	Belongs to the peptidase S11 family
GFH33_RS13835	COG2814	Major facilitator Superfamily
GFH33_RS13900	COG0741	lytic transglycosylase activity
GFH33_RS13910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS13915	COG2239	Acts as a magnesium transporter
GFH33_RS13990	COG5632	N-Acetylmuramoyl-L-alanine amidase
GFH33_RS13990	COG3409	Peptidoglycan-binding domain 1 protein
GFH33_RS14000	COG3831	ATPase activity
GFH33_RS14030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFH33_RS14060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFH33_RS14070	COG3850	Histidine kinase
GFH33_RS14070	COG5002	protein histidine kinase activity
GFH33_RS14075	COG0577	efflux transmembrane transporter activity
GFH33_RS14095	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GFH33_RS14105	COG1690	Belongs to the RtcB family
GFH33_RS14115	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GFH33_RS14130	COG2814	Major facilitator Superfamily
GFH33_RS14215	COG0346	lactoylglutathione lyase activity
GFH33_RS14230	COG1522	sequence-specific DNA binding
GFH33_RS14235	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS14240	COG1309	transcriptional regulator
GFH33_RS14245	COG2814	Major facilitator Superfamily
GFH33_RS14250	COG0640	Transcriptional regulator
GFH33_RS14255	COG0346	lactoylglutathione lyase activity
GFH33_RS14260	COG0798	PFAM Bile acid sodium symporter
GFH33_RS14270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS14280	COG1575	Belongs to the MenA family. Type 1 subfamily
GFH33_RS14285	COG0456	acetyltransferase
GFH33_RS14295	COG5609	conserved protein (DUF2294)
GFH33_RS14300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GFH33_RS14310	COG0288	reversible hydration of carbon dioxide
GFH33_RS14315	COG0657	acetylesterase activity
GFH33_RS14340	COG0415	Belongs to the DNA photolyase family
GFH33_RS14390	COG0598	Magnesium transport protein CorA
GFH33_RS14435	COG0583	DNA-binding transcription factor activity
GFH33_RS14455	COG1335	isochorismatase
GFH33_RS14460	COG2267	carboxylic ester hydrolase activity
GFH33_RS14465	COG0737	Belongs to the 5'-nucleotidase family
GFH33_RS14485	COG2207	Transcriptional regulator
GFH33_RS14515	COG5002	protein histidine kinase activity
GFH33_RS14525	COG1063	alcohol dehydrogenase
GFH33_RS14545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFH33_RS14555	COG1522	sequence-specific DNA binding
GFH33_RS14575	COG0574	Belongs to the PEP-utilizing enzyme family
GFH33_RS14575	COG3848	Pyruvate phosphate dikinase
GFH33_RS14600	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GFH33_RS14610	COG0454	-acetyltransferase
GFH33_RS14620	COG3314	Sporulation integral membrane protein YlbJ
GFH33_RS14635	COG1960	acyl-CoA dehydrogenase activity
GFH33_RS14645	COG0640	Transcriptional regulator
GFH33_RS14650	COG3142	Participates in the control of copper homeostasis
GFH33_RS14660	COG1414	Transcriptional regulator
GFH33_RS14665	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GFH33_RS14670	COG1984	allophanate hydrolase subunit 2
GFH33_RS14705	COG0768	penicillin binding
GFH33_RS14750	COG0833	amino acid
GFH33_RS14760	COG0730	response to heat
GFH33_RS14800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFH33_RS14805	COG0697	spore germination
GFH33_RS14820	COG0456	acetyltransferase
GFH33_RS14830	COG0037	tRNA processing
GFH33_RS14830	COG0590	tRNA wobble adenosine to inosine editing
GFH33_RS14855	COG3831	ATPase activity
GFH33_RS14855	COG4884	unkown
GFH33_RS14875	COG1846	Transcriptional regulator
GFH33_RS14880	COG0778	Nitroreductase
GFH33_RS14965	COG0714	Associated with various cellular activities
GFH33_RS15005	COG0753	catalase activity
GFH33_RS15010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GFH33_RS15030	COG0463	Glycosyl transferase, family 2
GFH33_RS15075	COG0714	Associated with various cellular activities
GFH33_RS15110	COG0346	lactoylglutathione lyase activity
GFH33_RS15115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS15135	COG3655	Transcriptional regulator
GFH33_RS15145	COG1785	Belongs to the alkaline phosphatase family
GFH33_RS15150	COG2720	vancomycin resistance protein
GFH33_RS15160	COG3239	Fatty acid desaturase
GFH33_RS15170	COG0833	amino acid
GFH33_RS15175	COG1414	Transcriptional regulator
GFH33_RS15180	COG4187	Peptidase family M20/M25/M40
GFH33_RS15185	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GFH33_RS15205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GFH33_RS15225	COG2329	Antibiotic biosynthesis monooxygenase
GFH33_RS15250	COG1070	Carbohydrate kinase
GFH33_RS15255	COG2390	Transcriptional regulator
GFH33_RS15265	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFH33_RS15275	COG1879	ABC-type sugar transport system periplasmic component
GFH33_RS15295	COG0277	FAD linked oxidase domain protein
GFH33_RS15310	COG1388	LysM domain
GFH33_RS15310	COG3584	3D domain protein
GFH33_RS15350	COG1605	Chorismate mutase
GFH33_RS15350	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GFH33_RS15365	COG0287	Prephenate dehydrogenase
GFH33_RS15380	COG1309	transcriptional regulator
GFH33_RS15400	COG0488	(ABC) transporter
GFH33_RS15405	COG1368	sulfuric ester hydrolase activity
GFH33_RS15410	COG0861	Integral membrane protein TerC family
GFH33_RS15420	COG0346	lactoylglutathione lyase activity
GFH33_RS15425	COG4912	Dna alkylation repair
GFH33_RS15450	COG0697	spore germination
GFH33_RS15470	COG2746	aminoglycoside 3-N-acetyltransferase activity
GFH33_RS15500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFH33_RS15505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFH33_RS15510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFH33_RS15525	COG0628	permease
GFH33_RS15575	COG1131	(ABC) transporter
GFH33_RS15590	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GFH33_RS15600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GFH33_RS15605	COG0436	Aminotransferase
GFH33_RS15640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GFH33_RS15655	COG2261	transglycosylase associated protein
GFH33_RS15680	COG2814	Major facilitator Superfamily
GFH33_RS15680	COG0477	Major facilitator Superfamily
GFH33_RS15685	COG4533	DNA binding
GFH33_RS15690	COG0789	Transcriptional regulator
GFH33_RS15695	COG1664	Polymer-forming cytoskeletal
GFH33_RS15705	COG2814	Major facilitator Superfamily
GFH33_RS15745	COG1307	EDD domain protein, DegV family
GFH33_RS15750	COG1164	Oligoendopeptidase f
GFH33_RS15760	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GFH33_RS15780	COG0745	RESPONSE REGULATOR receiver
GFH33_RS15785	COG3850	Histidine kinase
GFH33_RS15785	COG5002	protein histidine kinase activity
GFH33_RS15830	COG0667	Aldo Keto reductase
GFH33_RS15845	COG4948	Mandelate Racemase Muconate Lactonizing
GFH33_RS15855	COG4166	transmembrane transport
GFH33_RS15865	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GFH33_RS15875	COG0586	Pfam SNARE associated Golgi protein
GFH33_RS15915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFH33_RS15920	COG3938	Belongs to the proline racemase family
GFH33_RS15930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFH33_RS15935	COG1012	belongs to the aldehyde dehydrogenase family
GFH33_RS15940	COG1115	amino acid carrier protein
GFH33_RS15945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GFH33_RS15950	COG1162	GTPase activity
GFH33_RS15965	COG3397	chitin binding
GFH33_RS15980	COG4637	Psort location Cytoplasmic, score
GFH33_RS16025	COG0514	ATP-dependent DNA helicase (RecQ)
GFH33_RS16030	COG2105	PFAM AIG2 family protein
GFH33_RS16040	COG3973	AAA domain
GFH33_RS16045	COG0456	acetyltransferase
GFH33_RS16090	COG2315	Protein conserved in bacteria
GFH33_RS16095	COG2226	methyltransferase
GFH33_RS16100	COG2205	protein histidine kinase activity
GFH33_RS16120	COG1819	glycosyl
GFH33_RS16125	COG3397	chitin binding
GFH33_RS16130	COG2153	protein acetylation
GFH33_RS16160	COG4175	Glycine betaine
GFH33_RS16160	COG0517	IMP dehydrogenase activity
GFH33_RS16165	COG4176	ABC-type proline glycine betaine transport system permease component
GFH33_RS16205	COG0456	acetyltransferase
GFH33_RS16205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GFH33_RS16210	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS16225	COG3344	reverse transcriptase
GFH33_RS16240	COG2814	Major facilitator Superfamily
GFH33_RS16250	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GFH33_RS16255	COG0022	dehydrogenase e1 component
GFH33_RS16260	COG0508	dehydrogenase complex catalyzes the overall conversion of
GFH33_RS16265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFH33_RS16280	COG1959	2 iron, 2 sulfur cluster binding
GFH33_RS16310	COG3284	Transcriptional regulator
GFH33_RS16340	COG1309	transcriptional regulator
GFH33_RS16380	COG2959	enzyme of heme biosynthesis
GFH33_RS16395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS16430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFH33_RS16435	COG0697	spore germination
GFH33_RS16440	COG0201	protein transport
GFH33_RS16455	COG0737	Belongs to the 5'-nucleotidase family
GFH33_RS16460	COG3227	Zinc metalloprotease (Elastase)
GFH33_RS16465	COG1523	belongs to the glycosyl hydrolase 13 family
GFH33_RS16495	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GFH33_RS16510	COG0076	glutamate decarboxylase activity
GFH33_RS16515	COG0657	acetylesterase activity
GFH33_RS16520	COG1073	alpha beta
GFH33_RS16525	COG0577	efflux transmembrane transporter activity
GFH33_RS16530	COG1136	(ABC) transporter
GFH33_RS16545	COG5002	protein histidine kinase activity
GFH33_RS16550	COG0745	RESPONSE REGULATOR receiver
GFH33_RS16555	COG1011	Hydrolase
GFH33_RS16585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFH33_RS16605	COG0322	excinuclease ABC activity
GFH33_RS16645	COG4667	esterase of the alpha-beta hydrolase superfamily
GFH33_RS16665	COG3878	Protein conserved in bacteria
GFH33_RS16700	COG0592	DNA-directed DNA polymerase activity
GFH33_RS16715	COG2223	nitrite transmembrane transporter activity
GFH33_RS16725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GFH33_RS16760	COG0697	spore germination
GFH33_RS16765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFH33_RS16780	COG0584	glycerophosphoryl diester phosphodiesterase
GFH33_RS16800	COG2814	Major facilitator Superfamily
GFH33_RS16805	COG2814	Major facilitator Superfamily
GFH33_RS16850	COG0768	penicillin binding
GFH33_RS16855	COG0671	phosphoesterase, PA-phosphatase related
GFH33_RS16860	COG0604	alcohol dehydrogenase
GFH33_RS16865	COG5002	protein histidine kinase activity
GFH33_RS16870	COG0745	RESPONSE REGULATOR receiver
GFH33_RS16880	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GFH33_RS16895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GFH33_RS16945	COG2205	protein histidine kinase activity
GFH33_RS16970	COG1794	racemase activity, acting on amino acids and derivatives
GFH33_RS16975	COG1819	glycosyl
GFH33_RS16985	COG0768	penicillin binding
GFH33_RS16990	COG5002	protein histidine kinase activity
GFH33_RS16995	COG0561	phosphatase activity
GFH33_RS17030	COG2124	cytochrome p450
GFH33_RS17055	COG3547	Transposase (IS116 IS110 IS902 family)
GFH33_RS17095	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GFH33_RS17105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFH33_RS17110	COG0460	homoserine dehydrogenase
GFH33_RS17130	COG0577	efflux transmembrane transporter activity
GFH33_RS17135	COG1136	(ABC) transporter
GFH33_RS17145	COG0488	(ABC) transporter
GFH33_RS17155	COG3344	reverse transcriptase
GFH33_RS17165	COG0745	RESPONSE REGULATOR receiver
GFH33_RS17175	COG3773	Cell wall hydrolase
GFH33_RS17180	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GFH33_RS17190	COG3386	PFAM SMP-30 Gluconolaconase
GFH33_RS17200	COG0693	protein deglycase activity
GFH33_RS17205	COG2323	membrane
GFH33_RS17225	COG3344	reverse transcriptase
GFH33_RS17245	COG2368	4-hydroxyphenylacetate
GFH33_RS17250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFH33_RS17280	COG1131	(ABC) transporter
GFH33_RS17290	COG0583	DNA-binding transcription factor activity
GFH33_RS17295	COG1942	4-Oxalocrotonate Tautomerase
GFH33_RS17350	COG2207	Transcriptional regulator
GFH33_RS17355	COG3227	Zinc metalloprotease (Elastase)
GFH33_RS17370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GFH33_RS17420	COG0572	uridine kinase
GFH33_RS17435	COG3547	Transposase (IS116 IS110 IS902 family)
GFH33_RS17465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GFH33_RS17470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GFH33_RS17475	COG1024	Enoyl-CoA hydratase
GFH33_RS17480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFH33_RS17485	COG0511	ligase activity, forming carbon-carbon bonds
GFH33_RS17490	COG0439	Biotin carboxylase
GFH33_RS17495	COG1960	acyl-CoA dehydrogenase activity
GFH33_RS17510	COG1309	transcriptional regulator
GFH33_RS17520	COG1131	(ABC) transporter
GFH33_RS17535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFH33_RS17550	COG0768	penicillin binding
GFH33_RS17555	COG0768	penicillin binding
GFH33_RS17565	COG1595	DNA-templated transcription, initiation
GFH33_RS17570	COG0768	penicillin binding
GFH33_RS17580	COG2239	Acts as a magnesium transporter
GFH33_RS17585	COG0772	Belongs to the SEDS family
GFH33_RS17615	COG0076	glutamate decarboxylase activity
GFH33_RS17625	COG1533	DNA photolyase activity
GFH33_RS17650	COG0814	amino acid
GFH33_RS17655	COG1760	l-serine dehydratase
GFH33_RS17660	COG1760	l-serine dehydratase
GFH33_RS17685	COG0367	asparagine synthase
GFH33_RS17690	COG1309	transcriptional regulator
GFH33_RS17710	COG1396	sequence-specific DNA binding
GFH33_RS17830	COG5444	nuclease activity
GFH33_RS17855	COG1876	peptidase activity
GFH33_RS17860	COG2843	Capsule synthesis protein
GFH33_RS17870	COG0477	Major facilitator Superfamily
GFH33_RS17885	COG1846	Transcriptional regulator
GFH33_RS17890	COG2814	Major facilitator Superfamily
GFH33_RS17905	COG2031	fatty acid transporter
GFH33_RS17915	COG2249	NAD(P)H dehydrogenase (quinone) activity
GFH33_RS17970	COG1288	antiporter activity
GFH33_RS17990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GFH33_RS18000	COG1733	regulation of RNA biosynthetic process
GFH33_RS18005	COG0778	Nitroreductase
GFH33_RS18015	COG0469	pyruvate kinase activity
GFH33_RS18035	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS18045	COG1131	(ABC) transporter
GFH33_RS18070	COG1011	Hydrolase
GFH33_RS18080	COG2365	Tyrosine phosphatase family
GFH33_RS18115	COG0628	permease
GFH33_RS18140	COG0500	methyltransferase
GFH33_RS18150	COG0477	Major facilitator Superfamily
GFH33_RS18180	COG1253	flavin adenine dinucleotide binding
GFH33_RS18185	COG0789	Transcriptional regulator
GFH33_RS18195	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GFH33_RS18225	COG0697	spore germination
GFH33_RS18235	COG1357	PFAM Pentapeptide repeats (8 copies)
GFH33_RS18240	COG3813	Protein conserved in bacteria
GFH33_RS18245	COG2706	6-phosphogluconolactonase activity
GFH33_RS18250	COG1070	Carbohydrate kinase
GFH33_RS18260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GFH33_RS18265	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GFH33_RS18270	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GFH33_RS18275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GFH33_RS18300	COG0840	transmembrane signaling receptor activity
GFH33_RS18310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GFH33_RS18310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GFH33_RS18315	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GFH33_RS18315	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GFH33_RS18320	COG1733	regulation of RNA biosynthetic process
GFH33_RS18335	COG0814	amino acid
GFH33_RS18365	COG2188	Transcriptional regulator
GFH33_RS18370	COG0673	inositol 2-dehydrogenase activity
GFH33_RS18390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFH33_RS18410	COG0384	phenazine biosynthesis protein PhzF
GFH33_RS18430	COG0318	PFAM AMP-dependent synthetase and ligase
GFH33_RS18435	COG2249	NAD(P)H dehydrogenase (quinone) activity
GFH33_RS18440	COG1733	regulation of RNA biosynthetic process
GFH33_RS18465	COG1191	sigma factor activity
GFH33_RS18520	COG1151	hydroxylamine reductase activity
GFH33_RS18585	COG1113	amino acid transport
GFH33_RS18590	COG2814	Major facilitator Superfamily
GFH33_RS18620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GFH33_RS18625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GFH33_RS18635	COG1247	-acetyltransferase
GFH33_RS18640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GFH33_RS18645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFH33_RS18650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFH33_RS18655	COG3739	integral membrane protein
GFH33_RS18675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS18690	COG0583	DNA-binding transcription factor activity
GFH33_RS18700	COG2890	protein-(glutamine-N5) methyltransferase activity
GFH33_RS18715	COG1193	negative regulation of DNA recombination
GFH33_RS18725	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GFH33_RS18730	COG1164	Oligoendopeptidase f
GFH33_RS18755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GFH33_RS18780	COG0584	glycerophosphoryl diester phosphodiesterase
GFH33_RS18790	COG0640	Transcriptional regulator
GFH33_RS18795	COG0604	alcohol dehydrogenase
GFH33_RS18805	COG0457	Tetratricopeptide repeat
GFH33_RS18815	COG0385	Bile acid
GFH33_RS18820	COG0277	FAD linked oxidase domain protein
GFH33_RS18845	COG1183	phosphatidylcholine synthase activity
GFH33_RS18850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFH33_RS18850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFH33_RS18855	COG1252	NADH dehydrogenase
GFH33_RS18865	COG0823	Involved in the tonB-independent uptake of proteins
GFH33_RS18870	COG3397	chitin binding
GFH33_RS18880	COG0697	spore germination
GFH33_RS18910	COG3344	reverse transcriptase
GFH33_RS18930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GFH33_RS18940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFH33_RS18950	COG0457	Tetratricopeptide repeat
GFH33_RS18985	COG1404	Belongs to the peptidase S8 family
GFH33_RS19025	COG0488	(ABC) transporter
GFH33_RS19050	COG3852	Histidine kinase
GFH33_RS19060	COG1285	pathogenesis
GFH33_RS19070	COG2514	catechol 2,3-dioxygenase activity
GFH33_RS19075	COG2720	vancomycin resistance protein
GFH33_RS19110	COG0716	FMN binding
GFH33_RS19145	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS19155	COG0165	Argininosuccinate lyase
GFH33_RS19170	COG4145	pantothenate transmembrane transporter activity
GFH33_RS19180	COG1012	belongs to the aldehyde dehydrogenase family
GFH33_RS19185	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS19195	COG1657	PFAM Prenyltransferase squalene oxidase
GFH33_RS19200	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GFH33_RS19205	COG2962	Rard protein
GFH33_RS19210	COG3326	Membrane
GFH33_RS19225	COG0489	protein tyrosine kinase activity
GFH33_RS19235	COG0314	molybdopterin synthase activity
GFH33_RS19240	COG0303	'Molybdopterin
GFH33_RS19245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GFH33_RS19250	COG2116	formate transmembrane transporter activity
GFH33_RS19260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GFH33_RS19265	COG5609	conserved protein (DUF2294)
GFH33_RS19270	COG2427	Protein of unknown function (DUF1641)
GFH33_RS19275	COG3383	formate dehydrogenase (NAD+) activity
GFH33_RS19280	COG0697	spore germination
GFH33_RS19295	COG0531	amino acid
GFH33_RS19330	COG2226	methyltransferase
GFH33_RS19335	COG4166	transmembrane transport
GFH33_RS19340	COG4166	transmembrane transport
GFH33_RS19345	COG4166	transmembrane transport
GFH33_RS19350	COG1316	TRANSCRIPTIONal
GFH33_RS19360	COG1595	DNA-templated transcription, initiation
GFH33_RS19370	COG1131	(ABC) transporter
GFH33_RS19390	COG0673	inositol 2-dehydrogenase activity
GFH33_RS19395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GFH33_RS19400	COG0187	DNA topoisomerase II activity
GFH33_RS19405	COG1832	CoA-binding protein
GFH33_RS19410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFH33_RS19415	COG0745	RESPONSE REGULATOR receiver
GFH33_RS19425	COG1328	CTP reductase activity
GFH33_RS19425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GFH33_RS19435	COG4841	protein insertion into membrane
GFH33_RS19440	COG0824	Thioesterase
GFH33_RS19475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFH33_RS19490	COG1132	(ABC) transporter
GFH33_RS19495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GFH33_RS19525	COG2211	Major facilitator Superfamily
GFH33_RS19535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GFH33_RS19550	COG0183	Belongs to the thiolase family
GFH33_RS19555	COG0318	PFAM AMP-dependent synthetase and ligase
GFH33_RS19560	COG1268	BioY protein
GFH33_RS19565	COG0318	PFAM AMP-dependent synthetase and ligase
GFH33_RS19570	COG1396	sequence-specific DNA binding
GFH33_RS19595	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GFH33_RS19615	COG0830	nickel cation binding
GFH33_RS19655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFH33_RS19665	COG5002	protein histidine kinase activity
GFH33_RS19670	COG0400	carboxylic ester hydrolase activity
GFH33_RS19675	COG0346	lactoylglutathione lyase activity
GFH33_RS19690	COG0069	glutamate synthase activity
GFH33_RS19700	COG3344	reverse transcriptase
GFH33_RS19710	COG1329	Transcriptional regulator
GFH33_RS19715	COG0010	Belongs to the arginase family
GFH33_RS19740	COG2226	methyltransferase
GFH33_RS19765	COG4846	Membrane protein involved in cytochrome C biogenesis
GFH33_RS19770	COG0785	Cytochrome C biogenesis protein
GFH33_RS19780	COG1473	amidohydrolase
GFH33_RS19810	COG0583	DNA-binding transcription factor activity
GFH33_RS19820	COG1346	cytolysis
GFH33_RS19835	COG0730	response to heat
GFH33_RS19860	COG1132	(ABC) transporter
GFH33_RS19865	COG1132	(ABC) transporter
GFH33_RS19900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFH33_RS19925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GFH33_RS19945	COG1695	Transcriptional regulator
GFH33_RS19955	COG0174	glutamine synthetase
GFH33_RS19960	COG0789	Transcriptional regulator
GFH33_RS19965	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GFH33_RS19970	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GFH33_RS19975	COG2860	membrane
GFH33_RS19985	COG0464	growth
GFH33_RS20015	COG1388	LysM domain
GFH33_RS20015	COG3584	3D domain protein
GFH33_RS20020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFH33_RS20020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFH33_RS20020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFH33_RS20025	COG1105	Belongs to the carbohydrate kinase PfkB family
GFH33_RS20030	COG1349	DNA-binding transcription factor activity
GFH33_RS20035	COG1979	alcohol dehydrogenase
GFH33_RS20040	COG2322	membrane
GFH33_RS20050	COG1113	amino acid transport
GFH33_RS20060	COG1408	metallophosphoesterase
GFH33_RS20065	COG2116	formate transmembrane transporter activity
GFH33_RS20080	COG2217	Heavy metal translocating P-type atpase
GFH33_RS20085	COG2608	mercury ion transmembrane transporter activity
GFH33_RS20090	COG1937	Protein conserved in bacteria
GFH33_RS20100	COG2819	hydrolase of the alpha beta superfamily
GFH33_RS20105	COG1120	ATPase activity
GFH33_RS20110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFH33_RS20115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFH33_RS20120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GFH33_RS20130	COG2169	Transcriptional regulator
GFH33_RS20135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GFH33_RS20140	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GFH33_RS20160	COG2267	carboxylic ester hydrolase activity
GFH33_RS20165	COG3300	MHYT domain
GFH33_RS20165	COG5001	Diguanylate cyclase
GFH33_RS20185	COG1086	Polysaccharide biosynthesis protein
GFH33_RS20205	COG1346	cytolysis
GFH33_RS20215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFH33_RS20225	COG2188	Transcriptional regulator
GFH33_RS20230	COG2723	6-phospho-beta-galactosidase activity
GFH33_RS20235	COG0823	Involved in the tonB-independent uptake of proteins
GFH33_RS20240	COG1404	Belongs to the peptidase S8 family
GFH33_RS20245	COG3773	Cell wall hydrolase
GFH33_RS20255	COG1368	sulfuric ester hydrolase activity
GFH33_RS20260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GFH33_RS20285	COG4550	Control of competence regulator ComK, YlbF/YmcA
GFH33_RS20295	COG1013	pyruvate-flavodoxin oxidoreductase activity
GFH33_RS20300	COG0674	pyruvate-flavodoxin oxidoreductase activity
GFH33_RS20300	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GFH33_RS20310	COG2359	stage V sporulation protein S
GFH33_RS20315	COG1692	metallophosphoesterase
GFH33_RS20335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GFH33_RS20340	COG1426	Protein conserved in bacteria
GFH33_RS20355	COG0300	oxidoreductase activity
GFH33_RS20360	COG0612	Peptidase, M16
GFH33_RS20365	COG0612	Peptidase, M16
GFH33_RS20370	COG1079	Belongs to the binding-protein-dependent transport system permease family
GFH33_RS20375	COG4603	Belongs to the binding-protein-dependent transport system permease family
GFH33_RS20380	COG3845	ABC transporter
GFH33_RS20385	COG1744	ABC transporter substrate-binding protein PnrA-like
GFH33_RS20390	COG2188	Transcriptional regulator
GFH33_RS20405	COG0740	serine-type endopeptidase activity
GFH33_RS20410	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GFH33_RS20420	COG0527	aspartate kinase activity
GFH33_RS20425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GFH33_RS20430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GFH33_RS20435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GFH33_RS20440	COG1873	PFAM PRC-barrel domain
GFH33_RS20445	COG0612	Peptidase, M16
GFH33_RS20450	COG0726	polysaccharide deacetylase
GFH33_RS20465	COG0196	riboflavin kinase activity
GFH33_RS20475	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GFH33_RS20480	COG1550	Protein conserved in bacteria
GFH33_RS20490	COG1358	cellular component organization or biogenesis
GFH33_RS20495	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GFH33_RS20500	COG0195	Participates in both transcription termination and antitermination
GFH33_RS20520	COG0750	zinc metalloprotease
GFH33_RS20530	COG4589	Belongs to the CDS family
GFH33_RS20575	COG4974	Belongs to the 'phage' integrase family
GFH33_RS20585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GFH33_RS20590	COG0758	DNA mediated transformation
GFH33_RS20595	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GFH33_RS20635	COG1837	Belongs to the UPF0109 family
GFH33_RS20645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GFH33_RS20655	COG0552	protein localization to endoplasmic reticulum
GFH33_RS20665	COG3344	reverse transcriptase
GFH33_RS20680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFH33_RS20685	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS20690	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GFH33_RS20705	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GFH33_RS20710	COG1461	Dihydroxyacetone kinase
GFH33_RS20715	COG1302	Protein conserved in bacteria
GFH33_RS20730	COG1564	THIamine pyrophosphokinase
GFH33_RS20735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GFH33_RS20745	COG0515	serine threonine protein kinase
GFH33_RS20745	COG2815	serine threonine protein kinase
GFH33_RS20750	COG0631	protein serine/threonine phosphatase activity
GFH33_RS20760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GFH33_RS20760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GFH33_RS20775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GFH33_RS20780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GFH33_RS20800	COG1561	YicC-like family, N-terminal region
GFH33_RS20805	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GFH33_RS20815	COG0006	proline dipeptidase activity
GFH33_RS20830	COG3069	C4-dicarboxylate transmembrane transporter activity
GFH33_RS20890	COG0564	pseudouridine synthase activity
GFH33_RS20910	COG3599	regulation of cell shape
GFH33_RS20915	COG2302	S4 RNA-binding domain
GFH33_RS20920	COG0762	integral membrane protein
GFH33_RS20930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GFH33_RS20940	COG1873	PFAM PRC-barrel domain
GFH33_RS20945	COG1191	sigma factor activity
GFH33_RS20950	COG1191	sigma factor activity
GFH33_RS20960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GFH33_RS20965	COG0849	cell division
GFH33_RS20985	COG0772	Belongs to the SEDS family
GFH33_RS21005	COG0768	penicillin binding
GFH33_RS21010	COG0768	penicillin binding
GFH33_RS21030	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GFH33_RS21045	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GFH33_RS21050	COG1399	metal-binding, possibly nucleic acid-binding protein
GFH33_RS21060	COG3480	Lon protease (S16) C-terminal proteolytic domain
GFH33_RS21065	COG1752	Esterase of the alpha-beta hydrolase superfamily
GFH33_RS21070	COG3314	Sporulation integral membrane protein YlbJ
GFH33_RS21080	COG0742	ribosomal rna small subunit methyltransferase
GFH33_RS21095	COG3679	Belongs to the UPF0342 family
GFH33_RS21100	COG0406	alpha-ribazole phosphatase activity
GFH33_RS21115	COG2340	Cysteine-rich secretory protein family
GFH33_RS21130	COG3336	cytochrome c oxidase
GFH33_RS21165	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GFH33_RS21170	COG0772	Belongs to the SEDS family
GFH33_RS21180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GFH33_RS21185	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GFH33_RS21195	COG4896	Protein conserved in bacteria
GFH33_RS21210	COG1217	gtp-binding protein TYPA
GFH33_RS21220	COG0483	inositol monophosphate 1-phosphatase activity
GFH33_RS21240	COG1982	Orn Lys Arg decarboxylase major
GFH33_RS21285	COG0022	dehydrogenase e1 component
GFH33_RS21290	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GFH33_RS21305	COG0561	phosphatase activity
GFH33_RS21315	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GFH33_RS21320	COG0569	domain protein
GFH33_RS21340	COG0583	DNA-binding transcription factor activity
GFH33_RS21345	COG0517	IMP dehydrogenase activity
GFH33_RS21355	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GFH33_RS21365	COG4703	Protein of unknown function (DUF1797)
GFH33_RS21380	COG2200	EAL domain
GFH33_RS21385	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS21390	COG1408	metallophosphoesterase
GFH33_RS21435	COG2814	Major facilitator Superfamily
GFH33_RS21455	COG3209	COG3209 Rhs family protein
GFH33_RS21465	COG2205	protein histidine kinase activity
GFH33_RS21475	COG0436	Aminotransferase
GFH33_RS21480	COG1609	Transcriptional regulator
GFH33_RS21485	COG3833	ABC-type maltose transport systems, permease component
GFH33_RS21490	COG1175	transmembrane transport
GFH33_RS21495	COG2182	Extracellular solute-binding protein
GFH33_RS21505	COG0366	Alpha amylase catalytic
GFH33_RS21510	COG3842	ATPase activity
GFH33_RS21545	COG0183	Belongs to the thiolase family
GFH33_RS21580	COG1695	Transcriptional regulator
GFH33_RS21585	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS21605	COG4974	Belongs to the 'phage' integrase family
GFH33_RS21630	COG1012	belongs to the aldehyde dehydrogenase family
GFH33_RS21635	COG0640	Transcriptional regulator
GFH33_RS21665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFH33_RS21670	COG0436	Aminotransferase
GFH33_RS21705	COG2084	Dehydrogenase
GFH33_RS21715	COG2199	diguanylate cyclase activity
GFH33_RS21720	COG0778	Nitroreductase
GFH33_RS21745	COG2190	(PTS) system
GFH33_RS21745	COG1263	PTS System
GFH33_RS21745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFH33_RS21750	COG3711	transcriptional antiterminator
GFH33_RS21760	COG2188	Transcriptional regulator
GFH33_RS21770	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GFH33_RS21795	COG1547	Domain of unknown function (DUF309)
GFH33_RS21800	COG0456	acetyltransferase
GFH33_RS21805	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GFH33_RS21810	COG4086	secreted protein
GFH33_RS21815	COG0561	phosphatase activity
GFH33_RS21820	COG0697	spore germination
GFH33_RS21835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GFH33_RS21880	COG1686	Belongs to the peptidase S11 family
GFH33_RS21885	COG1725	Transcriptional regulator
GFH33_RS21890	COG1131	(ABC) transporter
GFH33_RS21905	COG1846	Transcriptional regulator
GFH33_RS21920	COG0598	Magnesium transport protein CorA
GFH33_RS21945	COG4974	Belongs to the 'phage' integrase family
GFH33_RS21955	COG0735	belongs to the Fur family
GFH33_RS21960	COG1300	Membrane
GFH33_RS21980	COG0667	Aldo Keto reductase
GFH33_RS21985	COG0656	L-ascorbic acid biosynthetic process
GFH33_RS21990	COG0456	acetyltransferase
GFH33_RS21990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GFH33_RS22000	COG4085	toxin activity
GFH33_RS22000	COG0737	Belongs to the 5'-nucleotidase family
GFH33_RS22000	COG1525	nuclease
GFH33_RS22010	COG0596	Alpha beta hydrolase
GFH33_RS22015	COG2056	Na+-H+ antiporter family
GFH33_RS22020	COG1609	Transcriptional regulator
GFH33_RS22025	COG0456	acetyltransferase
GFH33_RS22030	COG1073	alpha beta
GFH33_RS22045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GFH33_RS22045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GFH33_RS22050	COG0307	riboflavin synthase, alpha
GFH33_RS22080	COG1073	alpha beta
GFH33_RS22080	COG2226	methyltransferase
GFH33_RS22095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GFH33_RS22105	COG1757	Na H antiporter
GFH33_RS22110	COG0737	Belongs to the 5'-nucleotidase family
GFH33_RS22120	COG1522	sequence-specific DNA binding
GFH33_RS22165	COG0300	oxidoreductase activity
GFH33_RS22170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFH33_RS22175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GFH33_RS22180	COG1760	l-serine dehydratase
GFH33_RS22185	COG1760	l-serine dehydratase
GFH33_RS22220	COG1285	pathogenesis
GFH33_RS22230	COG2195	Cleaves the N-terminal amino acid of tripeptides
GFH33_RS22235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS22250	COG1376	ErfK ybiS ycfS ynhG family protein
GFH33_RS22255	COG4129	membrane
GFH33_RS22260	COG1126	abc transporter atp-binding protein
GFH33_RS22265	COG0765	amino acid transport
GFH33_RS22270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFH33_RS22290	COG2323	membrane
GFH33_RS22295	COG0772	Belongs to the SEDS family
GFH33_RS22300	COG0508	dehydrogenase complex catalyzes the overall conversion of
GFH33_RS22305	COG0022	dehydrogenase e1 component
GFH33_RS22310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GFH33_RS22315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFH33_RS22330	COG0280	phosphate acetyltransferase
GFH33_RS22335	COG3290	protein histidine kinase activity
GFH33_RS22335	COG3829	transcription factor binding
GFH33_RS22345	COG0584	glycerophosphoryl diester phosphodiesterase
GFH33_RS22350	COG3093	addiction module antidote protein HigA
GFH33_RS22365	COG0750	zinc metalloprotease
GFH33_RS22370	COG0497	DNA recombination
GFH33_RS22380	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GFH33_RS22390	COG0142	geranyltranstransferase activity
GFH33_RS22415	COG1302	Protein conserved in bacteria
GFH33_RS22420	COG0439	Biotin carboxylase
GFH33_RS22425	COG0511	ligase activity, forming carbon-carbon bonds
GFH33_RS22470	COG3854	ATPases associated with a variety of cellular activities
GFH33_RS22495	COG0006	proline dipeptidase activity
GFH33_RS22510	COG3872	metal-dependent enzyme
GFH33_RS22520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GFH33_RS22560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFH33_RS22570	COG1609	Transcriptional regulator
GFH33_RS22580	COG2076	Multidrug Resistance protein
GFH33_RS22585	COG2076	Multidrug Resistance protein
GFH33_RS22615	COG1131	(ABC) transporter
GFH33_RS22620	COG1725	Transcriptional regulator
GFH33_RS22650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GFH33_RS22715	COG1459	type II secretion system
GFH33_RS22720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GFH33_RS22775	COG1410	methionine synthase
GFH33_RS22775	COG0646	methionine synthase
GFH33_RS22780	COG0646	methionine synthase
GFH33_RS22780	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GFH33_RS22785	COG0626	cystathionine gamma-synthase activity
GFH33_RS22790	COG0626	cystathionine gamma-synthase activity
GFH33_RS22810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFH33_RS22820	COG1940	carbohydrate kinase activity
GFH33_RS22825	COG4483	Protein conserved in bacteria
GFH33_RS22830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GFH33_RS22835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GFH33_RS22840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GFH33_RS22845	COG0704	Plays a role in the regulation of phosphate uptake
GFH33_RS22855	COG0573	inorganic phosphate transmembrane transporter activity
GFH33_RS22860	COG0573	inorganic phosphate transmembrane transporter activity
GFH33_RS22865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GFH33_RS22870	COG0768	penicillin binding
GFH33_RS22875	COG0477	Major facilitator Superfamily
GFH33_RS22880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GFH33_RS22890	COG5521	maltodextrose utilization protein MalA
GFH33_RS22905	COG0735	belongs to the Fur family
GFH33_RS22910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GFH33_RS22915	COG1121	(ABC) transporter
GFH33_RS22920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFH33_RS22950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GFH33_RS22955	COG2384	SAM-dependent methyltransferase
GFH33_RS22965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GFH33_RS22970	COG0358	DNA primase activity
GFH33_RS22985	COG0517	IMP dehydrogenase activity
GFH33_RS23000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GFH33_RS23005	COG0295	cytidine deaminase activity
GFH33_RS23010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GFH33_RS23020	COG1480	7TM receptor with intracellular HD hydrolase
GFH33_RS23025	COG1702	phosphate starvation-inducible protein PhoH
GFH33_RS23040	COG1610	YqeY-like protein
GFH33_RS23045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GFH33_RS23050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GFH33_RS23055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GFH33_RS23085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GFH33_RS23090	COG1733	regulation of RNA biosynthetic process
GFH33_RS23115	COG1466	dna polymerase III delta subunit
GFH33_RS23125	COG0658	competence protein
GFH33_RS23125	COG2333	competence protein COMEC
GFH33_RS23130	COG2131	deaminase
GFH33_RS23135	COG1555	photosystem II stabilization
GFH33_RS23135	COG1596	polysaccharide export
GFH33_RS23140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GFH33_RS23145	COG2226	methyltransferase
GFH33_RS23150	COG0799	negative regulation of ribosome biogenesis
GFH33_RS23155	COG1713	HD superfamily hydrolase involved in NAD metabolism
GFH33_RS23165	COG1534	Rna-binding protein
GFH33_RS23175	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GFH33_RS23180	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GFH33_RS23205	COG1595	DNA-templated transcription, initiation
GFH33_RS23215	COG0778	Nitroreductase
GFH33_RS23220	COG2357	RelA SpoT domain protein
GFH33_RS23230	COG1785	Belongs to the alkaline phosphatase family
GFH33_RS23240	COG2267	carboxylic ester hydrolase activity
GFH33_RS23295	COG3186	Phenylalanine-4-hydroxylase
GFH33_RS23305	COG2514	catechol 2,3-dioxygenase activity
GFH33_RS23310	COG2259	Doxx family
GFH33_RS23350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GFH33_RS23360	COG1454	alcohol dehydrogenase
GFH33_RS23360	COG1012	belongs to the aldehyde dehydrogenase family
GFH33_RS23365	COG0626	cystathionine gamma-synthase activity
GFH33_RS23370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GFH33_RS23395	COG0768	penicillin binding
GFH33_RS23415	COG0826	peptidase U32
GFH33_RS23420	COG0826	peptidase U32
GFH33_RS23425	COG4122	O-methyltransferase activity
GFH33_RS23430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GFH33_RS23460	COG0628	permease
GFH33_RS23480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GFH33_RS23495	COG1104	cysteine desulfurase activity
GFH33_RS23500	COG1959	2 iron, 2 sulfur cluster binding
GFH33_RS23505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GFH33_RS23515	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GFH33_RS23540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GFH33_RS23550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GFH33_RS23550	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GFH33_RS23555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GFH33_RS23560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GFH33_RS23560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GFH33_RS23570	COG2244	polysaccharide biosynthetic process
GFH33_RS23575	COG2323	membrane
GFH33_RS23580	COG3547	Transposase (IS116 IS110 IS902 family)
GFH33_RS23590	COG1862	Preprotein translocase
GFH33_RS23620	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GFH33_RS23650	COG0157	Belongs to the NadC ModD family
GFH33_RS23655	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GFH33_RS23660	COG1104	cysteine desulfurase activity
GFH33_RS23665	COG1827	regulation of RNA biosynthetic process
GFH33_RS23670	COG2258	MOSC domain
GFH33_RS23675	COG0077	Prephenate dehydratase
GFH33_RS23680	COG0577	efflux transmembrane transporter activity
GFH33_RS23685	COG0577	efflux transmembrane transporter activity
GFH33_RS23690	COG1136	(ABC) transporter
GFH33_RS23695	COG5002	protein histidine kinase activity
GFH33_RS23700	COG0745	RESPONSE REGULATOR receiver
GFH33_RS23710	COG3290	protein histidine kinase activity
GFH33_RS23720	COG2868	ribosomal protein
GFH33_RS23730	COG1530	ribonuclease E activity
GFH33_RS23735	COG1994	Peptidase M50
GFH33_RS23740	COG0739	heme binding
GFH33_RS23745	COG2894	cell division
GFH33_RS23765	COG1077	Cell shape determining protein MreB Mrl
GFH33_RS23785	COG0285	dihydrofolate synthase activity
GFH33_RS23800	COG1388	LysM domain
GFH33_RS23810	COG0113	porphobilinogen synthase activity
GFH33_RS23815	COG1587	Uroporphyrinogen-III synthase
GFH33_RS23825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GFH33_RS23835	COG1846	Transcriptional regulator
GFH33_RS23840	COG1764	response to oxidative stress
GFH33_RS23855	COG0470	DNA polymerase III
GFH33_RS23855	COG1067	ATP-dependent peptidase activity
GFH33_RS23900	COG0622	Phosphoesterase
GFH33_RS23915	COG5401	PFAM Sporulation and spore germination
GFH33_RS23935	COG2197	response regulator
GFH33_RS23940	COG2233	PERMEase
GFH33_RS23945	COG0402	S-adenosylhomocysteine deaminase activity
GFH33_RS23950	COG1983	PspC domain protein
GFH33_RS23955	COG1396	sequence-specific DNA binding
GFH33_RS23960	COG0697	spore germination
GFH33_RS23970	COG1959	2 iron, 2 sulfur cluster binding
GFH33_RS23975	COG1668	transmembrane transport
GFH33_RS23980	COG4152	abc transporter atp-binding protein
GFH33_RS23985	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GFH33_RS23990	COG1360	Flagellar Motor Protein
GFH33_RS23995	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GFH33_RS24000	COG1876	peptidase activity
GFH33_RS24005	COG0824	Thioesterase
GFH33_RS24010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GFH33_RS24015	COG1053	succinate dehydrogenase
GFH33_RS24020	COG2009	succinate dehydrogenase
GFH33_RS24025	COG1719	4-vinyl reductase, 4VR
GFH33_RS24035	COG3118	belongs to the thioredoxin family
GFH33_RS24040	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GFH33_RS24045	COG2086	electron transfer activity
GFH33_RS24050	COG1024	Enoyl-CoA hydratase
GFH33_RS24055	COG1309	transcriptional regulator
GFH33_RS24060	COG0318	PFAM AMP-dependent synthetase and ligase
GFH33_RS24090	COG2318	DinB family
GFH33_RS24120	COG1131	(ABC) transporter
GFH33_RS24125	COG2205	protein histidine kinase activity
GFH33_RS24130	COG0745	RESPONSE REGULATOR receiver
GFH33_RS24140	COG4895	conserved protein (DUF2196)
GFH33_RS24145	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GFH33_RS24155	COG4509	Sortase family
GFH33_RS24160	COG1120	ATPase activity
GFH33_RS24175	COG5386	Cell surface protein
GFH33_RS24185	COG5386	Cell surface protein
GFH33_RS24190	COG1114	Component of the transport system for branched-chain amino acids
GFH33_RS24195	COG1187	pseudouridine synthase activity
GFH33_RS24205	COG1796	DNA polymerase
GFH33_RS24205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GFH33_RS24210	COG1286	toxin biosynthetic process
GFH33_RS24255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFH33_RS24265	COG1418	mRNA catabolic process
GFH33_RS24285	COG2814	Major facilitator Superfamily
GFH33_RS24290	COG1566	PFAM secretion protein HlyD family protein
GFH33_RS24295	COG1309	transcriptional regulator
GFH33_RS24300	COG1363	Peptidase, m42
GFH33_RS24325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GFH33_RS24340	COG1484	DNA-dependent DNA replication
GFH33_RS24345	COG3611	Membrane attachment protein
GFH33_RS24355	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GFH33_RS24360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GFH33_RS24370	COG1971	Probably functions as a manganese efflux pump
GFH33_RS24380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFH33_RS24380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFH33_RS24385	COG5002	protein histidine kinase activity
GFH33_RS24390	COG0745	RESPONSE REGULATOR receiver
GFH33_RS24410	COG0538	isocitrate dehydrogenase activity
GFH33_RS24415	COG0372	Belongs to the citrate synthase family
GFH33_RS24425	COG0628	permease
GFH33_RS24430	COG3030	protein affecting phage T7 exclusion by the F plasmid
GFH33_RS24455	COG1725	Transcriptional regulator
GFH33_RS24460	COG0281	malic enzyme
GFH33_RS24465	COG0587	DNA-directed DNA polymerase activity
GFH33_RS24480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GFH33_RS24495	COG4109	DRTGG domain
GFH33_RS24510	COG0006	proline dipeptidase activity
GFH33_RS24550	COG0662	Cupin 2, conserved barrel domain protein
GFH33_RS24565	COG1028	Short-chain dehydrogenase reductase Sdr
GFH33_RS24570	COG0589	response to stress
GFH33_RS24615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFH33_RS24640	COG0827	DNA restriction-modification system
GFH33_RS24645	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GFH33_RS24650	COG3874	Sporulation protein YtfJ
GFH33_RS24665	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GFH33_RS24675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GFH33_RS24690	COG1104	cysteine desulfurase activity
GFH33_RS24700	COG0583	DNA-binding transcription factor activity
GFH33_RS24705	COG0697	spore germination
GFH33_RS24710	COG1309	transcriptional regulator
GFH33_RS24715	COG1956	GAF domain-containing protein
GFH33_RS24720	COG0626	cystathionine gamma-synthase activity
GFH33_RS24775	COG1595	DNA-templated transcription, initiation
GFH33_RS24785	COG0110	maltose O-acetyltransferase activity
GFH33_RS24790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GFH33_RS24795	COG0454	-acetyltransferase
GFH33_RS24800	COG0517	IMP dehydrogenase activity
GFH33_RS24805	COG0123	including yeast histone deacetylase and acetoin utilization protein
GFH33_RS24820	COG0745	RESPONSE REGULATOR receiver
GFH33_RS24830	COG0666	response to abiotic stimulus
GFH33_RS24835	COG2972	Histidine kinase
GFH33_RS24835	COG0745	RESPONSE REGULATOR receiver
GFH33_RS24855	COG3279	Response regulator of the LytR AlgR family
GFH33_RS24890	COG1609	Transcriptional regulator
GFH33_RS24895	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GFH33_RS24895	COG1605	Chorismate mutase
GFH33_RS24900	COG4851	CamS sex pheromone cAM373 precursor
GFH33_RS24905	COG3118	belongs to the thioredoxin family
GFH33_RS24915	COG2309	aminopeptidase activity
GFH33_RS24930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS24945	COG1674	ftsk spoiiie
GFH33_RS24960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFH33_RS24970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFH33_RS24975	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GFH33_RS24980	COG1363	Peptidase, m42
GFH33_RS24990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFH33_RS25005	COG0510	thiamine kinase activity
GFH33_RS25010	COG1523	belongs to the glycosyl hydrolase 13 family
GFH33_RS25020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFH33_RS25025	COG1349	DNA-binding transcription factor activity
GFH33_RS25030	COG1187	pseudouridine synthase activity
GFH33_RS25035	COG2244	polysaccharide biosynthetic process
GFH33_RS25040	COG2081	HI0933 family
GFH33_RS25045	COG2814	Major facilitator Superfamily
GFH33_RS25055	COG3832	glyoxalase III activity
GFH33_RS25075	COG1329	Transcriptional regulator
GFH33_RS25100	COG0314	molybdopterin synthase activity
GFH33_RS25105	COG1763	Mo-molybdopterin cofactor biosynthetic process
GFH33_RS25110	COG0303	'Molybdopterin
GFH33_RS25120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GFH33_RS25125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GFH33_RS25145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFH33_RS25155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFH33_RS25200	COG2814	Major facilitator Superfamily
GFH33_RS25205	COG0475	glutathione-regulated potassium exporter activity
GFH33_RS25210	COG0490	domain, Protein
GFH33_RS25215	COG0582	viral genome integration into host DNA
GFH33_RS25225	COG1136	(ABC) transporter
GFH33_RS25245	COG1242	4 iron, 4 sulfur cluster binding
GFH33_RS25250	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GFH33_RS25255	COG1794	racemase activity, acting on amino acids and derivatives
GFH33_RS25275	COG2267	carboxylic ester hydrolase activity
GFH33_RS25280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GFH33_RS25285	COG0671	phosphoesterase, PA-phosphatase related
GFH33_RS25290	COG0438	transferase activity, transferring glycosyl groups
GFH33_RS25315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS25355	COG0546	phosphoglycolate phosphatase activity
GFH33_RS25360	COG1349	DNA-binding transcription factor activity
GFH33_RS25375	COG5002	protein histidine kinase activity
GFH33_RS25380	COG3852	Histidine kinase
GFH33_RS25385	COG2267	carboxylic ester hydrolase activity
GFH33_RS25390	COG1368	sulfuric ester hydrolase activity
GFH33_RS25415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFH33_RS25420	COG1116	anion transmembrane transporter activity
GFH33_RS25425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFH33_RS25450	COG0494	nUDIX hydrolase
GFH33_RS25480	COG1854	S-ribosylhomocysteine lyase activity
GFH33_RS25490	COG0288	reversible hydration of carbon dioxide
GFH33_RS25495	COG1271	oxidase subunit
GFH33_RS25500	COG1294	oxidase, subunit
GFH33_RS25515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFH33_RS25535	COG1842	Phage shock protein A
GFH33_RS25565	COG5002	protein histidine kinase activity
GFH33_RS25570	COG0745	RESPONSE REGULATOR receiver
GFH33_RS25595	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GFH33_RS25600	COG1597	lipid kinase activity
GFH33_RS25630	COG0586	Pfam SNARE associated Golgi protein
GFH33_RS25640	COG0577	efflux transmembrane transporter activity
GFH33_RS25645	COG1136	(ABC) transporter
GFH33_RS25650	COG2207	Transcriptional regulator
GFH33_RS25650	COG3708	Transcriptional regulator
GFH33_RS25660	COG5658	integral membrane protein
GFH33_RS25665	COG0640	Transcriptional regulator
GFH33_RS25670	COG0745	RESPONSE REGULATOR receiver
GFH33_RS25675	COG2205	protein histidine kinase activity
GFH33_RS25680	COG0577	efflux transmembrane transporter activity
GFH33_RS25685	COG0577	efflux transmembrane transporter activity
GFH33_RS25690	COG1136	(ABC) transporter
GFH33_RS25695	COG0577	efflux transmembrane transporter activity
GFH33_RS25725	COG2188	Transcriptional regulator
GFH33_RS25745	COG3964	amidohydrolase
GFH33_RS25765	COG4948	Mandelate Racemase Muconate Lactonizing
GFH33_RS25785	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GFH33_RS25790	COG0596	Alpha beta hydrolase
GFH33_RS25800	COG1169	isochorismate synthase
GFH33_RS25805	COG1575	Belongs to the MenA family. Type 1 subfamily
GFH33_RS25810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GFH33_RS25840	COG0058	SHG alpha-glucan phosphorylase activity
GFH33_RS25850	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GFH33_RS25965	COG0544	peptidyl-prolyl cis-trans isomerase activity
GFH33_RS26000	COG1285	pathogenesis
GFH33_RS26005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GFH33_RS26020	COG2155	Conserved Protein
GFH33_RS26025	COG1098	S1 RNA binding domain
GFH33_RS26030	COG0436	Aminotransferase
GFH33_RS26035	COG1522	sequence-specific DNA binding
GFH33_RS26040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GFH33_RS26045	COG2267	carboxylic ester hydrolase activity
GFH33_RS26055	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GFH33_RS26075	COG5018	Exonuclease
GFH33_RS26080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GFH33_RS26105	COG2050	protein possibly involved in aromatic compounds catabolism
GFH33_RS26115	COG1268	BioY protein
GFH33_RS26120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GFH33_RS26125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GFH33_RS26140	COG3584	3D domain protein
GFH33_RS26155	COG1252	NADH dehydrogenase
GFH33_RS26170	COG3708	Transcriptional regulator
GFH33_RS26185	COG1683	Conserved Protein
GFH33_RS26240	COG1388	LysM domain
GFH33_RS26240	COG3409	Peptidoglycan-binding domain 1 protein
GFH33_RS26240	COG5632	N-Acetylmuramoyl-L-alanine amidase
GFH33_RS26245	COG4824	toxin secretion phage lysis holin
GFH33_RS26300	COG0740	serine-type endopeptidase activity
GFH33_RS26310	COG1802	Transcriptional regulator
GFH33_RS26310	COG4626	Terminase
GFH33_RS26360	COG0582	viral genome integration into host DNA
GFH33_RS26445	COG1396	sequence-specific DNA binding
GFH33_RS26490	COG0316	Belongs to the HesB IscA family
GFH33_RS26505	COG1252	NADH dehydrogenase
GFH33_RS26520	COG0390	transport system, permease component
GFH33_RS26525	COG2824	Alkylphosphonate utilization operon protein PhnA
GFH33_RS26570	COG4837	Protein of unknown function (DUF1462)
GFH33_RS26575	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GFH33_RS26585	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GFH33_RS26590	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GFH33_RS26610	COG1358	cellular component organization or biogenesis
GFH33_RS26620	COG2249	NAD(P)H dehydrogenase (quinone) activity
GFH33_RS26625	COG0647	UMP catabolic process
GFH33_RS26635	COG2445	Protein of unknown function DUF86
GFH33_RS26640	COG1494	fructose-1,6-bisphosphatase
GFH33_RS26660	COG4470	Protein conserved in bacteria
GFH33_RS26670	COG0789	Transcriptional regulator
GFH33_RS26675	COG4377	Putative membrane peptidase family (DUF2324)
GFH33_RS26700	COG0739	heme binding
GFH33_RS26710	COG3377	Domain of unknown function (DUF1805)
GFH33_RS26715	COG0737	Belongs to the 5'-nucleotidase family
GFH33_RS26720	COG0719	Fe-S assembly protein
GFH33_RS26725	COG0822	iron-sulfur transferase activity
GFH33_RS26730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GFH33_RS26735	COG0719	Fe-S assembly protein
GFH33_RS26740	COG0396	ATPase activity
GFH33_RS26745	COG1464	Belongs to the NlpA lipoprotein family
GFH33_RS26750	COG1464	Belongs to the NlpA lipoprotein family
GFH33_RS26755	COG2011	ABC-type metal ion transport system permease component
GFH33_RS26770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GFH33_RS26775	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GFH33_RS26785	COG1393	Belongs to the ArsC family
GFH33_RS26805	COG0039	L-malate dehydrogenase activity
GFH33_RS26820	COG1309	transcriptional regulator
GFH33_RS26825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFH33_RS26830	COG1960	acyl-CoA dehydrogenase activity
GFH33_RS26835	COG0183	Belongs to the thiolase family
GFH33_RS26840	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFH33_RS26840	COG1024	Enoyl-CoA hydratase
GFH33_RS26850	COG1686	Belongs to the peptidase S11 family
GFH33_RS26865	COG0011	TIGRFAM Protein of
GFH33_RS26870	COG0840	transmembrane signaling receptor activity
GFH33_RS26885	COG2814	Major facilitator Superfamily
GFH33_RS26890	COG0531	amino acid
GFH33_RS26910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFH33_RS26945	COG0586	Pfam SNARE associated Golgi protein
GFH33_RS26955	COG1376	ErfK ybiS ycfS ynhG family protein
GFH33_RS26960	COG0745	RESPONSE REGULATOR receiver
GFH33_RS26965	COG5002	protein histidine kinase activity
GFH33_RS26995	COG0840	transmembrane signaling receptor activity
GFH33_RS27000	COG2151	metal-sulfur cluster biosynthetic enzyme
GFH33_RS27005	COG3227	Zinc metalloprotease (Elastase)
GFH33_RS27025	COG0586	Pfam SNARE associated Golgi protein
GFH33_RS27030	COG0475	glutathione-regulated potassium exporter activity
GFH33_RS27035	COG0490	domain, Protein
GFH33_RS27040	COG1115	amino acid carrier protein
GFH33_RS27045	COG0783	Belongs to the Dps family
GFH33_RS27060	COG1611	Belongs to the LOG family
GFH33_RS27070	COG1528	Iron-storage protein
GFH33_RS27075	COG2311	Membrane
GFH33_RS27080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GFH33_RS27105	COG1115	amino acid carrier protein
GFH33_RS27110	COG1115	amino acid carrier protein
GFH33_RS27115	COG2910	NAD(P)H-binding
GFH33_RS27130	COG0656	L-ascorbic acid biosynthetic process
GFH33_RS27135	COG2814	Major facilitator Superfamily
GFH33_RS27140	COG1733	regulation of RNA biosynthetic process
GFH33_RS27150	COG1252	NADH dehydrogenase
GFH33_RS27205	COG0488	(ABC) transporter
GFH33_RS27210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GFH33_RS27255	COG0745	RESPONSE REGULATOR receiver
GFH33_RS27270	COG3344	reverse transcriptase
GFH33_RS27295	COG0557	exoribonuclease II activity
GFH33_RS27300	COG1647	Serine aminopeptidase, S33
GFH33_RS27305	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GFH33_RS27310	COG1346	cytolysis
GFH33_RS27345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GFH33_RS27360	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GFH33_RS27390	COG0457	Tetratricopeptide repeat
GFH33_RS27395	COG1388	LysM domain
GFH33_RS27395	COG3409	Peptidoglycan-binding domain 1 protein
GFH33_RS27395	COG5632	N-Acetylmuramoyl-L-alanine amidase
GFH33_RS27400	COG3547	Transposase (IS116 IS110 IS902 family)
GFH33_RS27405	COG4824	toxin secretion phage lysis holin
GFH33_RS27410	COG3547	Transposase (IS116 IS110 IS902 family)
GFH33_RS27550	COG3331	DNA recombination
GFH33_RS27640	COG3646	Phage regulatory protein
GFH33_RS27670	COG0582	viral genome integration into host DNA
GFH33_RS27695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GFH33_RS27710	COG2323	membrane
GFH33_RS27720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFH33_RS27730	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GFH33_RS27740	COG1051	belongs to the nudix hydrolase family
GFH33_RS27750	COG0492	ferredoxin-NADP+ reductase activity
GFH33_RS27755	COG0457	Tetratricopeptide repeat
GFH33_RS27760	COG0110	maltose O-acetyltransferase activity
GFH33_RS27780	COG1950	PFAM Membrane protein of
GFH33_RS27790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GFH33_RS27795	COG0556	nucleotide-excision repair
GFH33_RS27810	COG0789	Transcriptional regulator
GFH33_RS27830	COG0583	DNA-binding transcription factor activity
GFH33_RS27840	COG0655	NAD(P)H dehydrogenase (quinone) activity
GFH33_RS27845	COG0488	(ABC) transporter
GFH33_RS27855	COG1132	(ABC) transporter
GFH33_RS27860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFH33_RS27865	COG3409	Peptidoglycan-binding domain 1 protein
GFH33_RS27865	COG0793	Belongs to the peptidase S41A family
GFH33_RS27870	COG2177	Part of the ABC transporter FtsEX involved in
GFH33_RS27875	COG2884	Cell division ATP-binding protein ftsE
GFH33_RS27900	COG1131	(ABC) transporter
GFH33_RS27930	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GFH33_RS27935	COG1278	Cold shock
GFH33_RS27940	COG1040	competence protein
GFH33_RS27945	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GFH33_RS27950	COG1388	LysM domain
GFH33_RS27950	COG0791	NLP P60 protein
GFH33_RS27955	COG1733	regulation of RNA biosynthetic process
GFH33_RS27960	COG1307	EDD domain protein, DegV family
GFH33_RS27965	COG1739	Uncharacterized protein family UPF0029
GFH33_RS27970	COG1316	TRANSCRIPTIONal
GFH33_RS27975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GFH33_RS27980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GFH33_RS27985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GFH33_RS27995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GFH33_RS27995	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GFH33_RS28015	COG1486	melibiose metabolic process
GFH33_RS28020	COG1447	Phosphotransferase system cellobiose-specific component IIA
GFH33_RS28025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFH33_RS28035	COG1447	Phosphotransferase system cellobiose-specific component IIA
GFH33_RS28045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFH33_RS28050	COG1301	dicarboxylic acid transport
GFH33_RS28065	COG1511	domain protein
GFH33_RS28070	COG0583	DNA-binding transcription factor activity
GFH33_RS28075	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GFH33_RS28085	COG1271	oxidase subunit
GFH33_RS28090	COG1294	oxidase, subunit
GFH33_RS28095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GFH33_RS28105	COG1620	l-lactate permease
GFH33_RS28120	COG2389	metal-binding protein
GFH33_RS28130	COG1368	sulfuric ester hydrolase activity
GFH33_RS28140	COG1388	LysM domain
GFH33_RS28140	COG0791	NLP P60 protein
GFH33_RS28145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GFH33_RS28155	COG1215	transferase activity, transferring glycosyl groups
GFH33_RS28160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GFH33_RS28165	COG1388	LysM domain
GFH33_RS28165	COG3584	3D domain protein
GFH33_RS28190	COG4715	Zinc finger, swim domain protein
GFH33_RS28195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GFH33_RS28235	COG0577	efflux transmembrane transporter activity
GFH33_RS28240	COG1136	(ABC) transporter
GFH33_RS28265	COG5002	protein histidine kinase activity
GFH33_RS28270	COG0745	RESPONSE REGULATOR receiver
GFH33_RS28280	COG1316	TRANSCRIPTIONal
GFH33_RS28285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GFH33_RS28295	COG1215	transferase activity, transferring glycosyl groups
GFH33_RS28300	COG0463	Glycosyl transferase, family 2
GFH33_RS28305	COG0438	transferase activity, transferring glycosyl groups
GFH33_RS28315	COG1216	Glycosyl transferase, family 2
GFH33_RS28330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GFH33_RS28335	COG4464	protein tyrosine phosphatase activity
GFH33_RS28340	COG0489	protein tyrosine kinase activity
GFH33_RS28345	COG3944	biosynthesis protein
GFH33_RS28350	COG0489	protein tyrosine kinase activity
GFH33_RS28365	COG1609	Transcriptional regulator
GFH33_RS28375	COG0739	heme binding
GFH33_RS28390	COG3279	Response regulator of the LytR AlgR family
GFH33_RS28395	COG2385	sporulation resulting in formation of a cellular spore
GFH33_RS28410	COG4836	Membrane
GFH33_RS28415	COG1007	ATP synthesis coupled electron transport
GFH33_RS28420	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GFH33_RS28425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GFH33_RS28435	COG0839	Belongs to the complex I subunit 6 family
GFH33_RS28455	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GFH33_RS28520	COG0356	it plays a direct role in the translocation of protons across the membrane
GFH33_RS28555	COG0698	ribose 5-phosphate isomerase
GFH33_RS28570	COG2259	Doxx family
GFH33_RS28575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFH33_RS28590	COG0009	L-threonylcarbamoyladenylate synthase
GFH33_RS28625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GFH33_RS28630	COG1494	fructose-1,6-bisphosphatase
GFH33_RS28650	COG4821	SIS domain
GFH33_RS28660	COG3343	RNA polymerase activity
GFH33_RS28670	COG1960	acyl-CoA dehydrogenase activity
GFH33_RS28675	COG1960	acyl-CoA dehydrogenase activity
GFH33_RS28680	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFH33_RS28685	COG0183	Belongs to the thiolase family
GFH33_RS28690	COG2181	nitrate reductase activity
GFH33_RS28690	COG0247	lactate metabolic process
GFH33_RS28695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFH33_RS28710	COG3344	reverse transcriptase
GFH33_RS28725	COG3300	MHYT domain
GFH33_RS28725	COG5001	Diguanylate cyclase
GFH33_RS28740	COG3227	Zinc metalloprotease (Elastase)
GFH33_RS28745	COG2197	response regulator
GFH33_RS28750	COG4585	Histidine kinase
GFH33_RS28755	COG0842	Transport permease protein
GFH33_RS28760	COG1131	(ABC) transporter
GFH33_RS28765	COG0024	Methionine aminopeptidase
GFH33_RS28775	COG2234	aminopeptidase activity
GFH33_RS28800	COG1595	DNA-templated transcription, initiation
GFH33_RS28810	COG4506	Protein conserved in bacteria
GFH33_RS28815	COG1619	proteins homologs of microcin C7 resistance protein MccF
GFH33_RS28840	COG2814	Major facilitator Superfamily
GFH33_RS28845	COG0789	Transcriptional regulator
GFH33_RS28850	COG0584	glycerophosphoryl diester phosphodiesterase
GFH33_RS28855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFH33_RS28865	COG1994	Peptidase M50
GFH33_RS28875	COG1078	dGTPase activity
GFH33_RS28880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GFH33_RS28885	COG1120	ATPase activity
GFH33_RS28890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFH33_RS28895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFH33_RS28915	COG0280	phosphate acetyltransferase
GFH33_RS28930	COG3773	Cell wall hydrolase
GFH33_RS28940	COG2363	Small membrane protein
GFH33_RS28950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GFH33_RS28955	COG2233	PERMEase
GFH33_RS28960	COG0561	phosphatase activity
GFH33_RS28965	COG2814	Major facilitator Superfamily
GFH33_RS28975	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GFH33_RS28980	COG1131	(ABC) transporter
GFH33_RS28985	COG2755	lipolytic protein G-D-S-L family
GFH33_RS28990	COG1609	Transcriptional regulator
GFH33_RS29000	COG0460	homoserine dehydrogenase
GFH33_RS29010	COG2873	o-acetylhomoserine
GFH33_RS29020	COG1011	Hydrolase
GFH33_RS29025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFH33_RS29035	COG2197	response regulator
GFH33_RS29040	COG2203	Gaf domain
GFH33_RS29040	COG4585	Histidine kinase
GFH33_RS29045	COG0351	phosphomethylpyrimidine kinase
GFH33_RS29050	COG3706	GGDEF domain
GFH33_RS29055	COG2879	small protein
GFH33_RS29060	COG1966	Carbon starvation protein
GFH33_RS29065	COG3279	Response regulator of the LytR AlgR family
GFH33_RS29070	COG0477	Major facilitator Superfamily
GFH33_RS29080	COG0438	transferase activity, transferring glycosyl groups
GFH33_RS29095	COG0840	transmembrane signaling receptor activity
GFH33_RS29105	COG1607	acyl-coa hydrolase
GFH33_RS29110	COG1216	Glycosyl transferase, family 2
GFH33_RS29125	COG1216	Glycosyl transferase, family 2
GFH33_RS29135	COG4485	Bacterial membrane protein, YfhO
GFH33_RS29140	COG0463	Glycosyl transferase, family 2
GFH33_RS29145	COG0488	(ABC) transporter
GFH33_RS29150	COG1309	transcriptional regulator
GFH33_RS29155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFH33_RS29160	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFH33_RS29160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFH33_RS29165	COG0628	permease
GFH33_RS29185	COG3275	phosphorelay sensor kinase activity
GFH33_RS29190	COG2814	Major facilitator Superfamily
GFH33_RS29195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GFH33_RS29200	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GFH33_RS29220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GFH33_RS29225	COG1272	protein, Hemolysin III
GFH33_RS29245	COG3344	reverse transcriptase
GFH33_RS29280	COG5002	protein histidine kinase activity
GFH33_RS29295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFH33_RS29300	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GFH33_RS29305	COG4853	Protein conserved in bacteria
GFH33_RS29315	COG5002	protein histidine kinase activity
GFH33_RS29320	COG0745	RESPONSE REGULATOR receiver
GFH33_RS29350	COG0305	Participates in initiation and elongation during chromosome replication
GFH33_RS29360	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GFH33_RS29365	COG4241	membrane
GFH33_RS29385	COG0012	GTP binding
GFH33_RS29390	COG4481	Protein conserved in bacteria
GFH33_RS29395	COG0668	transmembrane transport
GFH33_RS29405	COG1475	DNA binding
GFH33_RS29410	COG1192	Involved in chromosome partitioning
GFH33_RS29435	COG1847	R3H domain protein
GFH33_RS29450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GFH33_RS29460	COG3409	Peptidoglycan-binding domain 1 protein
GFH33_RS29460	COG5632	N-Acetylmuramoyl-L-alanine amidase
GFH33_RS29500	COG0659	secondary active sulfate transmembrane transporter activity
GFH33_RS29505	COG0589	response to stress
GFH33_RS29510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GFH33_RS29525	COG2323	membrane
GFH33_RS29530	COG1522	sequence-specific DNA binding
GFH33_RS29535	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GFH33_RS29590	COG4824	toxin secretion phage lysis holin
GFH33_RS29645	COG3409	Peptidoglycan-binding domain 1 protein
GFH33_RS29645	COG5632	N-Acetylmuramoyl-L-alanine amidase
GFH33_RS29650	COG0475	glutathione-regulated potassium exporter activity
GFH33_RS29655	COG0490	domain, Protein
GFH33_RS29665	COG0840	transmembrane signaling receptor activity
GFH33_RS29720	COG0583	DNA-binding transcription factor activity
GFH33_RS29760	COG0640	Transcriptional regulator
GFH33_RS29800	COG0675	Transposase, IS605 OrfB family
GFH33_RS29815	COG2828	Protein conserved in bacteria
GFH33_RS29850	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GFH33_RS29885	COG0457	Tetratricopeptide repeat
GFH33_RS30170	COG0592	DNA-directed DNA polymerase activity
GFH33_RS30175	COG4712	double-strand break repair protein
GFH33_RS30210	COG3344	reverse transcriptase
GFH33_RS30220	COG3344	reverse transcriptase
GFH33_RS30450	COG3344	reverse transcriptase
GFH33_RS30460	COG3344	reverse transcriptase
GFH33_RS30515	COG2311	Membrane
GFH33_RS30535	COG0457	Tetratricopeptide repeat
GFH33_RS30560	COG0583	DNA-binding transcription factor activity
GFH33_RS30565	COG0655	NAD(P)H dehydrogenase (quinone) activity
GFH33_RS30610	COG0730	response to heat
GFH33_RS30635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFH33_RS30665	COG2002	toxin-antitoxin pair type II binding
GFH33_RS30670	COG4166	transmembrane transport
GFH33_RS30690	COG4974	Belongs to the 'phage' integrase family
GFH33_RS30745	COG0653	protein targeting
GFH33_RS30760	COG0457	Tetratricopeptide repeat
GFH33_RS30790	COG0697	spore germination
GFH33_RS30800	COG3344	reverse transcriptase
GFH33_RS30825	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GFH33_RS30845	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GFH33_RS31010	COG0457	Tetratricopeptide repeat
GFH33_RS31055	COG0739	heme binding
GFH33_RS31215	COG0791	NLP P60 protein
GFH33_RS31215	COG0741	lytic transglycosylase activity
GFH33_RS31290	COG2323	membrane
GFH33_RS31295	COG1522	sequence-specific DNA binding
GFH33_RS31300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GFH33_RS31415	COG0358	DNA primase activity
GFH33_RS31545	COG0358	DNA primase activity
GFH33_RS31585	COG0457	Tetratricopeptide repeat
GFH33_RS31640	COG0457	Tetratricopeptide repeat
GFH33_RS31720	COG0457	Tetratricopeptide repeat
GFH33_RS31770	COG0457	Tetratricopeptide repeat
GFH33_RS31785	COG0457	Tetratricopeptide repeat
GFH33_RS31830	COG0457	Tetratricopeptide repeat
GFH33_RS31880	COG0457	Tetratricopeptide repeat
GFH33_RS31935	COG0457	Tetratricopeptide repeat
GFH33_RS31975	COG3654	unkown
GFH33_RS32025	COG3654	unkown