locus-tag	class	description
BTOYO_RS00040	COG1011	Hydrolase
BTOYO_RS00045	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS00050	COG5002	protein histidine kinase activity
BTOYO_RS00080	COG1136	(ABC) transporter
BTOYO_RS00095	COG1073	alpha beta
BTOYO_RS00100	COG0657	acetylesterase activity
BTOYO_RS00105	COG0076	glutamate decarboxylase activity
BTOYO_RS00120	COG1523	belongs to the glycosyl hydrolase 13 family
BTOYO_RS00125	COG3227	Zinc metalloprotease (Elastase)
BTOYO_RS00130	COG0737	Belongs to the 5'-nucleotidase family
BTOYO_RS00140	COG0201	protein transport
BTOYO_RS00145	COG0697	spore germination
BTOYO_RS00150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTOYO_RS00185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTOYO_RS00200	COG2959	enzyme of heme biosynthesis
BTOYO_RS00240	COG1309	transcriptional regulator
BTOYO_RS00250	COG3284	Transcriptional regulator
BTOYO_RS00265	COG1349	DNA-binding transcription factor activity
BTOYO_RS00285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTOYO_RS00290	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTOYO_RS00295	COG0022	dehydrogenase e1 component
BTOYO_RS00300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTOYO_RS00310	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS00340	COG4176	ABC-type proline glycine betaine transport system permease component
BTOYO_RS00345	COG0517	IMP dehydrogenase activity
BTOYO_RS00345	COG4175	Glycine betaine
BTOYO_RS00375	COG2153	protein acetylation
BTOYO_RS00390	COG3397	chitin binding
BTOYO_RS00400	COG1819	glycosyl
BTOYO_RS00420	COG2205	protein histidine kinase activity
BTOYO_RS00425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTOYO_RS00430	COG2315	Protein conserved in bacteria
BTOYO_RS00480	COG3973	AAA domain
BTOYO_RS00490	COG0514	ATP-dependent DNA helicase (RecQ)
BTOYO_RS00515	COG4637	Psort location Cytoplasmic, score
BTOYO_RS00530	COG3397	chitin binding
BTOYO_RS00535	COG2318	DinB family
BTOYO_RS00550	COG1162	GTPase activity
BTOYO_RS00555	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTOYO_RS00560	COG1115	amino acid carrier protein
BTOYO_RS00565	COG1012	belongs to the aldehyde dehydrogenase family
BTOYO_RS00570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTOYO_RS00575	COG3938	Belongs to the proline racemase family
BTOYO_RS00580	COG3938	Belongs to the proline racemase family
BTOYO_RS00585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTOYO_RS00640	COG0586	Pfam SNARE associated Golgi protein
BTOYO_RS00655	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BTOYO_RS00660	COG4166	transmembrane transport
BTOYO_RS00670	COG4948	Mandelate Racemase Muconate Lactonizing
BTOYO_RS00720	COG2936	dipeptidyl-peptidase activity
BTOYO_RS00725	COG3850	Histidine kinase
BTOYO_RS00725	COG5002	protein histidine kinase activity
BTOYO_RS00730	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS00755	COG1164	Oligoendopeptidase f
BTOYO_RS00760	COG0456	acetyltransferase
BTOYO_RS00765	COG1307	EDD domain protein, DegV family
BTOYO_RS00800	COG2814	Major facilitator Superfamily
BTOYO_RS00810	COG1664	Polymer-forming cytoskeletal
BTOYO_RS00815	COG0789	Transcriptional regulator
BTOYO_RS00820	COG4533	DNA binding
BTOYO_RS00825	COG0477	Major facilitator Superfamily
BTOYO_RS00825	COG2814	Major facilitator Superfamily
BTOYO_RS00850	COG2261	transglycosylase associated protein
BTOYO_RS00865	COG2226	methyltransferase
BTOYO_RS00900	COG0436	Aminotransferase
BTOYO_RS00905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTOYO_RS00930	COG1131	(ABC) transporter
BTOYO_RS00975	COG0628	permease
BTOYO_RS00985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTOYO_RS00990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTOYO_RS00995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTOYO_RS01025	COG2746	aminoglycoside 3-N-acetyltransferase activity
BTOYO_RS01035	COG2801	Transposase and inactivated derivatives
BTOYO_RS01065	COG0697	spore germination
BTOYO_RS01095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTOYO_RS01100	COG0346	lactoylglutathione lyase activity
BTOYO_RS01105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTOYO_RS01130	COG2814	Major facilitator Superfamily
BTOYO_RS01135	COG0861	Integral membrane protein TerC family
BTOYO_RS01140	COG1368	sulfuric ester hydrolase activity
BTOYO_RS01145	COG0488	(ABC) transporter
BTOYO_RS01150	COG2409	Drug exporters of the RND superfamily
BTOYO_RS01150	COG1033	growth of symbiont in host cell
BTOYO_RS01155	COG1309	transcriptional regulator
BTOYO_RS01160	COG1051	belongs to the nudix hydrolase family
BTOYO_RS01175	COG0287	Prephenate dehydrogenase
BTOYO_RS01190	COG1605	Chorismate mutase
BTOYO_RS01190	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTOYO_RS01230	COG3584	3D domain protein
BTOYO_RS01230	COG1388	LysM domain
BTOYO_RS01240	COG0346	lactoylglutathione lyase activity
BTOYO_RS01245	COG0519	Catalyzes the synthesis of GMP from XMP
BTOYO_RS01250	COG0431	NADPH-dependent FMN reductase
BTOYO_RS01275	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTOYO_RS01280	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTOYO_RS01290	COG2390	Transcriptional regulator
BTOYO_RS01295	COG1070	Carbohydrate kinase
BTOYO_RS01325	COG2329	Antibiotic biosynthesis monooxygenase
BTOYO_RS01345	COG1472	Belongs to the glycosyl hydrolase 3 family
BTOYO_RS01350	COG2207	Transcriptional regulator
BTOYO_RS01355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTOYO_RS01360	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BTOYO_RS01365	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BTOYO_RS01370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTOYO_RS01375	COG4187	Peptidase family M20/M25/M40
BTOYO_RS01380	COG1414	Transcriptional regulator
BTOYO_RS01385	COG0833	amino acid
BTOYO_RS01395	COG3239	Fatty acid desaturase
BTOYO_RS01400	COG2720	vancomycin resistance protein
BTOYO_RS01405	COG1785	Belongs to the alkaline phosphatase family
BTOYO_RS01415	COG3655	Transcriptional regulator
BTOYO_RS01440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTOYO_RS01445	COG0346	lactoylglutathione lyase activity
BTOYO_RS01465	COG0714	Associated with various cellular activities
BTOYO_RS01480	COG2801	Transposase and inactivated derivatives
BTOYO_RS01500	COG0753	catalase activity
BTOYO_RS01540	COG0714	Associated with various cellular activities
BTOYO_RS01580	COG0778	Nitroreductase
BTOYO_RS01585	COG1846	Transcriptional regulator
BTOYO_RS01605	COG3831	ATPase activity
BTOYO_RS01605	COG4884	unkown
BTOYO_RS01640	COG0456	acetyltransferase
BTOYO_RS01660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTOYO_RS01675	COG0642	Histidine kinase
BTOYO_RS01680	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS01685	COG0596	Alpha beta hydrolase
BTOYO_RS01715	COG0730	response to heat
BTOYO_RS01725	COG0833	amino acid
BTOYO_RS01735	COG4335	DNA alkylation repair
BTOYO_RS01765	COG0768	penicillin binding
BTOYO_RS01795	COG1984	allophanate hydrolase subunit 2
BTOYO_RS01800	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BTOYO_RS01805	COG1414	Transcriptional regulator
BTOYO_RS01825	COG3142	Participates in the control of copper homeostasis
BTOYO_RS01835	COG1960	acyl-CoA dehydrogenase activity
BTOYO_RS01850	COG3314	Sporulation integral membrane protein YlbJ
BTOYO_RS01880	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BTOYO_RS01900	COG0574	Belongs to the PEP-utilizing enzyme family
BTOYO_RS01900	COG3848	Pyruvate phosphate dikinase
BTOYO_RS01915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BTOYO_RS01925	COG1876	peptidase activity
BTOYO_RS01930	COG0737	Belongs to the 5'-nucleotidase family
BTOYO_RS01935	COG2267	carboxylic ester hydrolase activity
BTOYO_RS01940	COG1335	isochorismatase
BTOYO_RS01960	COG0583	DNA-binding transcription factor activity
BTOYO_RS01965	COG1846	Transcriptional regulator
BTOYO_RS01970	COG0598	Magnesium transport protein CorA
BTOYO_RS02005	COG0415	Belongs to the DNA photolyase family
BTOYO_RS02010	COG0288	reversible hydration of carbon dioxide
BTOYO_RS02020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTOYO_RS02025	COG5609	conserved protein (DUF2294)
BTOYO_RS02030	COG2814	Major facilitator Superfamily
BTOYO_RS02035	COG0583	DNA-binding transcription factor activity
BTOYO_RS02070	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS02075	COG0456	acetyltransferase
BTOYO_RS02080	COG1575	Belongs to the MenA family. Type 1 subfamily
BTOYO_RS02085	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTOYO_RS02090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTOYO_RS02095	COG1121	(ABC) transporter
BTOYO_RS02110	COG1999	signal sequence binding
BTOYO_RS02115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BTOYO_RS02120	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BTOYO_RS02140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTOYO_RS02155	COG0798	PFAM Bile acid sodium symporter
BTOYO_RS02160	COG0346	lactoylglutathione lyase activity
BTOYO_RS02165	COG0640	Transcriptional regulator
BTOYO_RS02180	COG0825	malonyl-CoA metabolic process
BTOYO_RS02190	COG3320	Male sterility
BTOYO_RS02190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTOYO_RS02195	COG1309	transcriptional regulator
BTOYO_RS02205	COG2186	Transcriptional regulator
BTOYO_RS02220	COG0814	amino acid
BTOYO_RS02225	COG2801	Transposase and inactivated derivatives
BTOYO_RS02240	COG0697	spore germination
BTOYO_RS02245	COG2814	Major facilitator Superfamily
BTOYO_RS02255	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS02260	COG1522	sequence-specific DNA binding
BTOYO_RS02275	COG0346	lactoylglutathione lyase activity
BTOYO_RS02335	COG0384	phenazine biosynthesis protein PhzF
BTOYO_RS02340	COG2814	Major facilitator Superfamily
BTOYO_RS02345	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BTOYO_RS02360	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BTOYO_RS02380	COG0577	efflux transmembrane transporter activity
BTOYO_RS02400	COG3850	Histidine kinase
BTOYO_RS02400	COG5002	protein histidine kinase activity
BTOYO_RS02410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTOYO_RS02425	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTOYO_RS02445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTOYO_RS02490	COG2814	Major facilitator Superfamily
BTOYO_RS02520	COG4282	regulation of fungal-type cell wall biogenesis
BTOYO_RS02565	COG1876	peptidase activity
BTOYO_RS02570	COG2843	Capsule synthesis protein
BTOYO_RS02580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTOYO_RS02585	COG1012	belongs to the aldehyde dehydrogenase family
BTOYO_RS02595	COG0534	Mate efflux family protein
BTOYO_RS02600	COG1012	belongs to the aldehyde dehydrogenase family
BTOYO_RS02605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTOYO_RS02620	COG0477	Major facilitator Superfamily
BTOYO_RS02635	COG1846	Transcriptional regulator
BTOYO_RS02640	COG2814	Major facilitator Superfamily
BTOYO_RS02690	COG2356	endonuclease I
BTOYO_RS02700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTOYO_RS02705	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BTOYO_RS02725	COG1733	regulation of RNA biosynthetic process
BTOYO_RS02730	COG0778	Nitroreductase
BTOYO_RS02765	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS02775	COG1131	(ABC) transporter
BTOYO_RS02800	COG1011	Hydrolase
BTOYO_RS02810	COG2365	Tyrosine phosphatase family
BTOYO_RS02835	COG0346	lactoylglutathione lyase activity
BTOYO_RS02840	COG1940	carbohydrate kinase activity
BTOYO_RS02850	COG0110	maltose O-acetyltransferase activity
BTOYO_RS02865	COG0628	permease
BTOYO_RS02900	COG0477	Major facilitator Superfamily
BTOYO_RS02920	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BTOYO_RS02930	COG1253	flavin adenine dinucleotide binding
BTOYO_RS02935	COG0789	Transcriptional regulator
BTOYO_RS02945	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTOYO_RS02970	COG0697	spore germination
BTOYO_RS02980	COG1357	PFAM Pentapeptide repeats (8 copies)
BTOYO_RS02985	COG3813	Protein conserved in bacteria
BTOYO_RS02990	COG2706	6-phosphogluconolactonase activity
BTOYO_RS02995	COG1070	Carbohydrate kinase
BTOYO_RS03005	COG2610	gluconate transmembrane transporter activity
BTOYO_RS03015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BTOYO_RS03025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTOYO_RS03030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTOYO_RS03065	COG0814	amino acid
BTOYO_RS03070	COG3655	Transcriptional regulator
BTOYO_RS03100	COG1393	Belongs to the ArsC family
BTOYO_RS03105	COG1733	regulation of RNA biosynthetic process
BTOYO_RS03110	COG2188	Transcriptional regulator
BTOYO_RS03115	COG0673	inositol 2-dehydrogenase activity
BTOYO_RS03135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTOYO_RS03165	COG0318	PFAM AMP-dependent synthetase and ligase
BTOYO_RS03170	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTOYO_RS03175	COG1733	regulation of RNA biosynthetic process
BTOYO_RS03210	COG1191	sigma factor activity
BTOYO_RS03220	COG1280	lysine exporter protein (LysE YggA)
BTOYO_RS03265	COG1151	hydroxylamine reductase activity
BTOYO_RS03275	COG3757	hydrolase, family 25
BTOYO_RS03275	COG3409	Peptidoglycan-binding domain 1 protein
BTOYO_RS03310	COG2072	flavoprotein involved in K transport
BTOYO_RS03345	COG0604	alcohol dehydrogenase
BTOYO_RS03350	COG1113	amino acid transport
BTOYO_RS03355	COG0456	acetyltransferase
BTOYO_RS03360	COG2814	Major facilitator Superfamily
BTOYO_RS03410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BTOYO_RS03415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTOYO_RS03430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTOYO_RS03435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTOYO_RS03440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTOYO_RS03445	COG3739	integral membrane protein
BTOYO_RS03470	COG0583	DNA-binding transcription factor activity
BTOYO_RS03500	COG1193	negative regulation of DNA recombination
BTOYO_RS03510	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BTOYO_RS03515	COG1164	Oligoendopeptidase f
BTOYO_RS03540	COG3781	membrane
BTOYO_RS03555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTOYO_RS03570	COG0583	DNA-binding transcription factor activity
BTOYO_RS03580	COG0584	glycerophosphoryl diester phosphodiesterase
BTOYO_RS03595	COG0640	Transcriptional regulator
BTOYO_RS03600	COG0604	alcohol dehydrogenase
BTOYO_RS03610	COG0457	Tetratricopeptide repeat
BTOYO_RS03620	COG2808	Putative FMN-binding domain
BTOYO_RS03625	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTOYO_RS03635	COG0277	FAD linked oxidase domain protein
BTOYO_RS03650	COG3858	chitin binding
BTOYO_RS03660	COG5001	Diguanylate cyclase
BTOYO_RS03660	COG3300	MHYT domain
BTOYO_RS03670	COG1876	peptidase activity
BTOYO_RS03700	COG3852	Histidine kinase
BTOYO_RS03710	COG1285	pathogenesis
BTOYO_RS03720	COG2514	catechol 2,3-dioxygenase activity
BTOYO_RS03725	COG2720	vancomycin resistance protein
BTOYO_RS03760	COG0716	FMN binding
BTOYO_RS03790	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS03800	COG0165	Argininosuccinate lyase
BTOYO_RS03815	COG4145	pantothenate transmembrane transporter activity
BTOYO_RS03825	COG1012	belongs to the aldehyde dehydrogenase family
BTOYO_RS03830	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS03840	COG1657	PFAM Prenyltransferase squalene oxidase
BTOYO_RS03845	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BTOYO_RS03850	COG2962	Rard protein
BTOYO_RS03855	COG3326	Membrane
BTOYO_RS03870	COG0489	protein tyrosine kinase activity
BTOYO_RS03880	COG0314	molybdopterin synthase activity
BTOYO_RS03885	COG0303	'Molybdopterin
BTOYO_RS03890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTOYO_RS03895	COG2116	formate transmembrane transporter activity
BTOYO_RS03905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTOYO_RS03910	COG5609	conserved protein (DUF2294)
BTOYO_RS03915	COG2427	Protein of unknown function (DUF1641)
BTOYO_RS03920	COG3383	formate dehydrogenase (NAD+) activity
BTOYO_RS03935	COG0531	amino acid
BTOYO_RS03970	COG2226	methyltransferase
BTOYO_RS03975	COG4166	transmembrane transport
BTOYO_RS03980	COG4166	transmembrane transport
BTOYO_RS03985	COG4166	transmembrane transport
BTOYO_RS03990	COG1301	dicarboxylic acid transport
BTOYO_RS03995	COG1316	TRANSCRIPTIONal
BTOYO_RS04015	COG1131	(ABC) transporter
BTOYO_RS04025	COG0673	inositol 2-dehydrogenase activity
BTOYO_RS04030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTOYO_RS04035	COG0187	DNA topoisomerase II activity
BTOYO_RS04040	COG1832	CoA-binding protein
BTOYO_RS04045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTOYO_RS04050	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS04070	COG4841	protein insertion into membrane
BTOYO_RS04075	COG0824	Thioesterase
BTOYO_RS04100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTOYO_RS04110	COG1132	(ABC) transporter
BTOYO_RS04115	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTOYO_RS04145	COG2211	Major facilitator Superfamily
BTOYO_RS04155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTOYO_RS04170	COG0183	Belongs to the thiolase family
BTOYO_RS04175	COG0318	PFAM AMP-dependent synthetase and ligase
BTOYO_RS04180	COG1268	BioY protein
BTOYO_RS04185	COG0318	PFAM AMP-dependent synthetase and ligase
BTOYO_RS04190	COG1396	sequence-specific DNA binding
BTOYO_RS04230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTOYO_RS04240	COG5002	protein histidine kinase activity
BTOYO_RS04245	COG0400	carboxylic ester hydrolase activity
BTOYO_RS04250	COG0346	lactoylglutathione lyase activity
BTOYO_RS04255	COG0069	glutamate synthase activity
BTOYO_RS04260	COG1902	pentaerythritol trinitrate reductase activity
BTOYO_RS04265	COG1329	Transcriptional regulator
BTOYO_RS04270	COG0010	Belongs to the arginase family
BTOYO_RS04295	COG2226	methyltransferase
BTOYO_RS04320	COG4846	Membrane protein involved in cytochrome C biogenesis
BTOYO_RS04325	COG0785	Cytochrome C biogenesis protein
BTOYO_RS04335	COG1473	amidohydrolase
BTOYO_RS04345	COG1131	(ABC) transporter
BTOYO_RS04360	COG0583	DNA-binding transcription factor activity
BTOYO_RS04370	COG1346	cytolysis
BTOYO_RS04385	COG0730	response to heat
BTOYO_RS04415	COG1132	(ABC) transporter
BTOYO_RS04420	COG1132	(ABC) transporter
BTOYO_RS04425	COG3763	UPF0154 protein
BTOYO_RS04445	COG3639	organic phosphonate transmembrane transporter activity
BTOYO_RS04470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTOYO_RS04490	COG1695	Transcriptional regulator
BTOYO_RS04495	COG1132	(ABC) transporter
BTOYO_RS04525	COG0367	asparagine synthase
BTOYO_RS04530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BTOYO_RS04540	COG1181	Belongs to the D-alanine--D-alanine ligase family
BTOYO_RS04545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTOYO_RS04550	COG3420	alginic acid biosynthetic process
BTOYO_RS04550	COG5434	Belongs to the glycosyl hydrolase 28 family
BTOYO_RS04575	COG0438	transferase activity, transferring glycosyl groups
BTOYO_RS04585	COG0463	Glycosyl transferase, family 2
BTOYO_RS04585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BTOYO_RS04590	COG0438	transferase activity, transferring glycosyl groups
BTOYO_RS04595	COG0438	transferase activity, transferring glycosyl groups
BTOYO_RS04605	COG0489	protein tyrosine kinase activity
BTOYO_RS04625	COG1196	nuclear chromosome segregation
BTOYO_RS04625	COG0739	heme binding
BTOYO_RS04625	COG0741	lytic transglycosylase activity
BTOYO_RS04630	COG0741	lytic transglycosylase activity
BTOYO_RS04665	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BTOYO_RS04670	COG0174	glutamine synthetase
BTOYO_RS04675	COG0789	Transcriptional regulator
BTOYO_RS04680	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BTOYO_RS04685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTOYO_RS04690	COG2860	membrane
BTOYO_RS04700	COG0464	growth
BTOYO_RS04740	COG3584	3D domain protein
BTOYO_RS04740	COG1388	LysM domain
BTOYO_RS04745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTOYO_RS04745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTOYO_RS04745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTOYO_RS04750	COG1105	Belongs to the carbohydrate kinase PfkB family
BTOYO_RS04755	COG1349	DNA-binding transcription factor activity
BTOYO_RS04760	COG1979	alcohol dehydrogenase
BTOYO_RS04765	COG2322	membrane
BTOYO_RS04780	COG1113	amino acid transport
BTOYO_RS04790	COG1473	amidohydrolase
BTOYO_RS04795	COG1408	metallophosphoesterase
BTOYO_RS04810	COG2217	Heavy metal translocating P-type atpase
BTOYO_RS04815	COG2608	mercury ion transmembrane transporter activity
BTOYO_RS04820	COG1937	Protein conserved in bacteria
BTOYO_RS04840	COG2819	hydrolase of the alpha beta superfamily
BTOYO_RS04845	COG1120	ATPase activity
BTOYO_RS04850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTOYO_RS04855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTOYO_RS04860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTOYO_RS04865	COG0708	Exodeoxyribonuclease III
BTOYO_RS04870	COG2169	Transcriptional regulator
BTOYO_RS04875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTOYO_RS04880	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BTOYO_RS04890	COG2364	Membrane
BTOYO_RS04905	COG2267	carboxylic ester hydrolase activity
BTOYO_RS04910	COG3300	MHYT domain
BTOYO_RS04910	COG5001	Diguanylate cyclase
BTOYO_RS04950	COG1346	cytolysis
BTOYO_RS04960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTOYO_RS04965	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTOYO_RS04965	COG0596	Alpha beta hydrolase
BTOYO_RS04970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BTOYO_RS04985	COG1404	Belongs to the peptidase S8 family
BTOYO_RS04990	COG3773	Cell wall hydrolase
BTOYO_RS05005	COG1368	sulfuric ester hydrolase activity
BTOYO_RS05020	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BTOYO_RS05035	COG4550	Control of competence regulator ComK, YlbF/YmcA
BTOYO_RS05045	COG1013	pyruvate-flavodoxin oxidoreductase activity
BTOYO_RS05050	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BTOYO_RS05050	COG0674	pyruvate-flavodoxin oxidoreductase activity
BTOYO_RS05060	COG2359	stage V sporulation protein S
BTOYO_RS05065	COG1692	metallophosphoesterase
BTOYO_RS05100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTOYO_RS05105	COG1426	Protein conserved in bacteria
BTOYO_RS05120	COG0300	oxidoreductase activity
BTOYO_RS05125	COG0612	Peptidase, M16
BTOYO_RS05130	COG0612	Peptidase, M16
BTOYO_RS05135	COG1079	Belongs to the binding-protein-dependent transport system permease family
BTOYO_RS05140	COG4603	Belongs to the binding-protein-dependent transport system permease family
BTOYO_RS05145	COG3845	ABC transporter
BTOYO_RS05150	COG1744	ABC transporter substrate-binding protein PnrA-like
BTOYO_RS05155	COG2188	Transcriptional regulator
BTOYO_RS05160	COG1674	ftsk spoiiie
BTOYO_RS05170	COG0740	serine-type endopeptidase activity
BTOYO_RS05175	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTOYO_RS05185	COG0527	aspartate kinase activity
BTOYO_RS05190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTOYO_RS05195	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTOYO_RS05200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTOYO_RS05205	COG1873	PFAM PRC-barrel domain
BTOYO_RS05210	COG0612	Peptidase, M16
BTOYO_RS05215	COG0726	polysaccharide deacetylase
BTOYO_RS05230	COG0196	riboflavin kinase activity
BTOYO_RS05240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BTOYO_RS05245	COG1550	Protein conserved in bacteria
BTOYO_RS05255	COG1358	cellular component organization or biogenesis
BTOYO_RS05260	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BTOYO_RS05265	COG0195	Participates in both transcription termination and antitermination
BTOYO_RS05285	COG0750	zinc metalloprotease
BTOYO_RS05295	COG4589	Belongs to the CDS family
BTOYO_RS05310	COG0528	UMP kinase activity
BTOYO_RS05315	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BTOYO_RS05350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTOYO_RS05355	COG0758	DNA mediated transformation
BTOYO_RS05360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BTOYO_RS05385	COG0335	large ribosomal subunit rRNA binding
BTOYO_RS05400	COG1837	Belongs to the UPF0109 family
BTOYO_RS05410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTOYO_RS05420	COG0552	protein localization to endoplasmic reticulum
BTOYO_RS05425	COG1196	nuclear chromosome segregation
BTOYO_RS05435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTOYO_RS05440	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS05445	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BTOYO_RS05460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BTOYO_RS05465	COG1461	Dihydroxyacetone kinase
BTOYO_RS05470	COG1302	Protein conserved in bacteria
BTOYO_RS05485	COG1564	THIamine pyrophosphokinase
BTOYO_RS05490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BTOYO_RS05495	COG1162	GTPase activity
BTOYO_RS05500	COG0515	serine threonine protein kinase
BTOYO_RS05500	COG2815	serine threonine protein kinase
BTOYO_RS05505	COG0631	protein serine/threonine phosphatase activity
BTOYO_RS05515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTOYO_RS05515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTOYO_RS05520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTOYO_RS05530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BTOYO_RS05535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTOYO_RS05555	COG1561	YicC-like family, N-terminal region
BTOYO_RS05560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BTOYO_RS05570	COG0006	proline dipeptidase activity
BTOYO_RS05590	COG3069	C4-dicarboxylate transmembrane transporter activity
BTOYO_RS05645	COG3069	C4-dicarboxylate transmembrane transporter activity
BTOYO_RS05705	COG0564	pseudouridine synthase activity
BTOYO_RS05725	COG3599	regulation of cell shape
BTOYO_RS05730	COG2302	S4 RNA-binding domain
BTOYO_RS05735	COG0762	integral membrane protein
BTOYO_RS05745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BTOYO_RS05755	COG1873	PFAM PRC-barrel domain
BTOYO_RS05760	COG1191	sigma factor activity
BTOYO_RS05765	COG1191	sigma factor activity
BTOYO_RS05775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BTOYO_RS05780	COG0849	cell division
BTOYO_RS05800	COG0772	Belongs to the SEDS family
BTOYO_RS05820	COG0768	penicillin binding
BTOYO_RS05825	COG0768	penicillin binding
BTOYO_RS05845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTOYO_RS05860	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BTOYO_RS05865	COG1399	metal-binding, possibly nucleic acid-binding protein
BTOYO_RS05875	COG3480	Lon protease (S16) C-terminal proteolytic domain
BTOYO_RS05880	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTOYO_RS05885	COG3314	Sporulation integral membrane protein YlbJ
BTOYO_RS05895	COG0742	ribosomal rna small subunit methyltransferase
BTOYO_RS05910	COG3679	Belongs to the UPF0342 family
BTOYO_RS05915	COG0406	alpha-ribazole phosphatase activity
BTOYO_RS05930	COG2340	Cysteine-rich secretory protein family
BTOYO_RS05945	COG3336	cytochrome c oxidase
BTOYO_RS05980	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BTOYO_RS05985	COG0772	Belongs to the SEDS family
BTOYO_RS05995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BTOYO_RS06000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BTOYO_RS06010	COG4896	Protein conserved in bacteria
BTOYO_RS06025	COG1217	gtp-binding protein TYPA
BTOYO_RS06035	COG0483	inositol monophosphate 1-phosphatase activity
BTOYO_RS06055	COG1982	Orn Lys Arg decarboxylase major
BTOYO_RS06115	COG0022	dehydrogenase e1 component
BTOYO_RS06120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTOYO_RS06135	COG0561	phosphatase activity
BTOYO_RS06140	COG5503	Protein of unknown function (DUF1447)
BTOYO_RS06145	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTOYO_RS06150	COG0569	domain protein
BTOYO_RS06165	COG2171	N-acyltransferase activity
BTOYO_RS06170	COG0583	DNA-binding transcription factor activity
BTOYO_RS06175	COG0517	IMP dehydrogenase activity
BTOYO_RS06185	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BTOYO_RS06195	COG4703	Protein of unknown function (DUF1797)
BTOYO_RS06215	COG2200	EAL domain
BTOYO_RS06220	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS06225	COG1408	metallophosphoesterase
BTOYO_RS06235	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BTOYO_RS06270	COG2814	Major facilitator Superfamily
BTOYO_RS06290	COG3209	COG3209 Rhs family protein
BTOYO_RS06300	COG2205	protein histidine kinase activity
BTOYO_RS06310	COG0436	Aminotransferase
BTOYO_RS06315	COG1609	Transcriptional regulator
BTOYO_RS06320	COG3833	ABC-type maltose transport systems, permease component
BTOYO_RS06325	COG1175	transmembrane transport
BTOYO_RS06330	COG2182	Extracellular solute-binding protein
BTOYO_RS06340	COG0366	Alpha amylase catalytic
BTOYO_RS06345	COG3842	ATPase activity
BTOYO_RS06390	COG0183	Belongs to the thiolase family
BTOYO_RS06425	COG1695	Transcriptional regulator
BTOYO_RS06430	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS06445	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BTOYO_RS06450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTOYO_RS06455	COG0436	Aminotransferase
BTOYO_RS06490	COG2084	Dehydrogenase
BTOYO_RS06500	COG2199	diguanylate cyclase activity
BTOYO_RS06505	COG0778	Nitroreductase
BTOYO_RS06530	COG2190	(PTS) system
BTOYO_RS06530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTOYO_RS06530	COG1263	PTS System
BTOYO_RS06535	COG3711	transcriptional antiterminator
BTOYO_RS06545	COG2188	Transcriptional regulator
BTOYO_RS06555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BTOYO_RS06575	COG1547	Domain of unknown function (DUF309)
BTOYO_RS06580	COG0456	acetyltransferase
BTOYO_RS06585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTOYO_RS06590	COG4086	secreted protein
BTOYO_RS06595	COG0561	phosphatase activity
BTOYO_RS06600	COG0697	spore germination
BTOYO_RS06615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTOYO_RS06640	COG0733	neurotransmitter:sodium symporter activity
BTOYO_RS06665	COG1725	Transcriptional regulator
BTOYO_RS06670	COG1131	(ABC) transporter
BTOYO_RS06690	COG1846	Transcriptional regulator
BTOYO_RS06705	COG0598	Magnesium transport protein CorA
BTOYO_RS06730	COG4974	Belongs to the 'phage' integrase family
BTOYO_RS06740	COG0735	belongs to the Fur family
BTOYO_RS06745	COG1300	Membrane
BTOYO_RS06765	COG0667	Aldo Keto reductase
BTOYO_RS06770	COG0656	L-ascorbic acid biosynthetic process
BTOYO_RS06775	COG0456	acetyltransferase
BTOYO_RS06775	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTOYO_RS06785	COG1525	nuclease
BTOYO_RS06785	COG4085	toxin activity
BTOYO_RS06785	COG0737	Belongs to the 5'-nucleotidase family
BTOYO_RS06795	COG0596	Alpha beta hydrolase
BTOYO_RS06800	COG2056	Na+-H+ antiporter family
BTOYO_RS06805	COG1609	Transcriptional regulator
BTOYO_RS06810	COG0454	-acetyltransferase
BTOYO_RS06815	COG1073	alpha beta
BTOYO_RS06830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTOYO_RS06830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTOYO_RS06835	COG0307	riboflavin synthase, alpha
BTOYO_RS06860	COG4106	trans-aconitate 2-methyltransferase activity
BTOYO_RS06865	COG1073	alpha beta
BTOYO_RS06865	COG2226	methyltransferase
BTOYO_RS06880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTOYO_RS06890	COG1757	Na H antiporter
BTOYO_RS06895	COG0737	Belongs to the 5'-nucleotidase family
BTOYO_RS06905	COG1522	sequence-specific DNA binding
BTOYO_RS06940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BTOYO_RS06955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTOYO_RS06960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTOYO_RS06965	COG1760	l-serine dehydratase
BTOYO_RS06970	COG1760	l-serine dehydratase
BTOYO_RS06995	COG1285	pathogenesis
BTOYO_RS07005	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTOYO_RS07010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTOYO_RS07020	COG1376	ErfK ybiS ycfS ynhG family protein
BTOYO_RS07025	COG4129	membrane
BTOYO_RS07030	COG1126	abc transporter atp-binding protein
BTOYO_RS07035	COG0765	amino acid transport
BTOYO_RS07040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTOYO_RS07050	COG2816	NAD+ diphosphatase activity
BTOYO_RS07055	COG2323	membrane
BTOYO_RS07060	COG0772	Belongs to the SEDS family
BTOYO_RS07065	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTOYO_RS07070	COG0022	dehydrogenase e1 component
BTOYO_RS07075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTOYO_RS07080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTOYO_RS07095	COG0280	phosphate acetyltransferase
BTOYO_RS07100	COG3829	transcription factor binding
BTOYO_RS07100	COG3290	protein histidine kinase activity
BTOYO_RS07110	COG0584	glycerophosphoryl diester phosphodiesterase
BTOYO_RS07115	COG3093	addiction module antidote protein HigA
BTOYO_RS07120	COG1215	transferase activity, transferring glycosyl groups
BTOYO_RS07130	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS07135	COG0750	zinc metalloprotease
BTOYO_RS07140	COG0497	DNA recombination
BTOYO_RS07150	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BTOYO_RS07160	COG0142	geranyltranstransferase activity
BTOYO_RS07180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTOYO_RS07185	COG1302	Protein conserved in bacteria
BTOYO_RS07190	COG0439	Biotin carboxylase
BTOYO_RS07195	COG0511	ligase activity, forming carbon-carbon bonds
BTOYO_RS07240	COG3854	ATPases associated with a variety of cellular activities
BTOYO_RS07265	COG0006	proline dipeptidase activity
BTOYO_RS07290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTOYO_RS07320	COG0095	Lipoate-protein ligase
BTOYO_RS07325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTOYO_RS07335	COG1609	Transcriptional regulator
BTOYO_RS07345	COG2076	Multidrug Resistance protein
BTOYO_RS07350	COG2076	Multidrug Resistance protein
BTOYO_RS07380	COG1131	(ABC) transporter
BTOYO_RS07385	COG1725	Transcriptional regulator
BTOYO_RS07400	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BTOYO_RS07410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BTOYO_RS07415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTOYO_RS07470	COG4970	Tfp pilus assembly protein FimT
BTOYO_RS07480	COG1459	type II secretion system
BTOYO_RS07485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BTOYO_RS07540	COG1410	methionine synthase
BTOYO_RS07540	COG0646	methionine synthase
BTOYO_RS07545	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BTOYO_RS07545	COG0646	methionine synthase
BTOYO_RS07550	COG0626	cystathionine gamma-synthase activity
BTOYO_RS07555	COG0626	cystathionine gamma-synthase activity
BTOYO_RS07580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTOYO_RS07590	COG1940	carbohydrate kinase activity
BTOYO_RS07595	COG4483	Protein conserved in bacteria
BTOYO_RS07600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTOYO_RS07605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BTOYO_RS07610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTOYO_RS07615	COG0704	Plays a role in the regulation of phosphate uptake
BTOYO_RS07625	COG0581	inorganic phosphate transmembrane transporter activity
BTOYO_RS07630	COG0573	inorganic phosphate transmembrane transporter activity
BTOYO_RS07635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BTOYO_RS07640	COG0768	penicillin binding
BTOYO_RS07645	COG0477	Major facilitator Superfamily
BTOYO_RS07650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTOYO_RS07675	COG0735	belongs to the Fur family
BTOYO_RS07680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTOYO_RS07685	COG1121	(ABC) transporter
BTOYO_RS07690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTOYO_RS07720	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BTOYO_RS07725	COG2384	SAM-dependent methyltransferase
BTOYO_RS07730	COG2010	Cytochrome c
BTOYO_RS07735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTOYO_RS07740	COG0358	DNA primase activity
BTOYO_RS07745	COG1671	Belongs to the UPF0178 family
BTOYO_RS07755	COG0517	IMP dehydrogenase activity
BTOYO_RS07770	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BTOYO_RS07775	COG0295	cytidine deaminase activity
BTOYO_RS07780	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BTOYO_RS07785	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BTOYO_RS07790	COG1480	7TM receptor with intracellular HD hydrolase
BTOYO_RS07795	COG1702	phosphate starvation-inducible protein PhoH
BTOYO_RS07810	COG1610	YqeY-like protein
BTOYO_RS07815	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BTOYO_RS07820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTOYO_RS07825	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BTOYO_RS07835	COG0484	heat shock protein binding
BTOYO_RS07850	COG1420	regulation of RNA biosynthetic process
BTOYO_RS07855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTOYO_RS07860	COG1733	regulation of RNA biosynthetic process
BTOYO_RS07885	COG1466	dna polymerase III delta subunit
BTOYO_RS07895	COG2333	competence protein COMEC
BTOYO_RS07895	COG0658	competence protein
BTOYO_RS07900	COG2131	deaminase
BTOYO_RS07905	COG1555	photosystem II stabilization
BTOYO_RS07905	COG1596	polysaccharide export
BTOYO_RS07910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTOYO_RS07915	COG2226	methyltransferase
BTOYO_RS07920	COG0799	negative regulation of ribosome biogenesis
BTOYO_RS07925	COG1713	HD superfamily hydrolase involved in NAD metabolism
BTOYO_RS07930	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BTOYO_RS07935	COG1534	Rna-binding protein
BTOYO_RS07945	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BTOYO_RS07950	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BTOYO_RS07985	COG0778	Nitroreductase
BTOYO_RS07990	COG2357	RelA SpoT domain protein
BTOYO_RS08000	COG1785	Belongs to the alkaline phosphatase family
BTOYO_RS08010	COG2267	carboxylic ester hydrolase activity
BTOYO_RS08045	COG1404	Belongs to the peptidase S8 family
BTOYO_RS08050	COG3186	Phenylalanine-4-hydroxylase
BTOYO_RS08060	COG2514	catechol 2,3-dioxygenase activity
BTOYO_RS08065	COG2259	Doxx family
BTOYO_RS08105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTOYO_RS08115	COG1012	belongs to the aldehyde dehydrogenase family
BTOYO_RS08115	COG1454	alcohol dehydrogenase
BTOYO_RS08120	COG0626	cystathionine gamma-synthase activity
BTOYO_RS08125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTOYO_RS08150	COG0768	penicillin binding
BTOYO_RS08165	COG0826	peptidase U32
BTOYO_RS08170	COG0826	peptidase U32
BTOYO_RS08175	COG4122	O-methyltransferase activity
BTOYO_RS08180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BTOYO_RS08195	COG4472	Bacterial protein of unknown function (DUF965)
BTOYO_RS08210	COG0628	permease
BTOYO_RS08245	COG1104	cysteine desulfurase activity
BTOYO_RS08250	COG1959	2 iron, 2 sulfur cluster binding
BTOYO_RS08255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BTOYO_RS08265	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BTOYO_RS08300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTOYO_RS08315	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTOYO_RS08320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTOYO_RS08320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTOYO_RS08345	COG1862	Preprotein translocase
BTOYO_RS08350	COG0343	queuine tRNA-ribosyltransferase activity
BTOYO_RS08365	COG2255	four-way junction helicase activity
BTOYO_RS08370	COG0632	four-way junction helicase activity
BTOYO_RS08375	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BTOYO_RS08405	COG0157	Belongs to the NadC ModD family
BTOYO_RS08410	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BTOYO_RS08415	COG1104	cysteine desulfurase activity
BTOYO_RS08420	COG1827	regulation of RNA biosynthetic process
BTOYO_RS08425	COG2258	MOSC domain
BTOYO_RS08430	COG0077	Prephenate dehydratase
BTOYO_RS08435	COG0577	efflux transmembrane transporter activity
BTOYO_RS08440	COG0577	efflux transmembrane transporter activity
BTOYO_RS08445	COG1136	(ABC) transporter
BTOYO_RS08450	COG5002	protein histidine kinase activity
BTOYO_RS08455	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS08465	COG3290	protein histidine kinase activity
BTOYO_RS08475	COG2868	ribosomal protein
BTOYO_RS08485	COG1530	ribonuclease E activity
BTOYO_RS08490	COG1994	Peptidase M50
BTOYO_RS08495	COG0739	heme binding
BTOYO_RS08500	COG2894	cell division
BTOYO_RS08520	COG1077	Cell shape determining protein MreB Mrl
BTOYO_RS08540	COG0285	dihydrofolate synthase activity
BTOYO_RS08555	COG1388	LysM domain
BTOYO_RS08565	COG0113	porphobilinogen synthase activity
BTOYO_RS08570	COG1587	Uroporphyrinogen-III synthase
BTOYO_RS08580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTOYO_RS08590	COG1846	Transcriptional regulator
BTOYO_RS08595	COG1764	response to oxidative stress
BTOYO_RS08610	COG1067	ATP-dependent peptidase activity
BTOYO_RS08610	COG0470	DNA polymerase III
BTOYO_RS08650	COG0622	Phosphoesterase
BTOYO_RS08665	COG5401	PFAM Sporulation and spore germination
BTOYO_RS08680	COG2197	response regulator
BTOYO_RS08690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTOYO_RS08750	COG2197	response regulator
BTOYO_RS08755	COG2233	PERMEase
BTOYO_RS08760	COG0402	S-adenosylhomocysteine deaminase activity
BTOYO_RS08765	COG1983	PspC domain protein
BTOYO_RS08770	COG1396	sequence-specific DNA binding
BTOYO_RS08775	COG0697	spore germination
BTOYO_RS08785	COG1959	2 iron, 2 sulfur cluster binding
BTOYO_RS08790	COG1668	transmembrane transport
BTOYO_RS08795	COG4152	abc transporter atp-binding protein
BTOYO_RS08800	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BTOYO_RS08805	COG1360	Flagellar Motor Protein
BTOYO_RS08810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BTOYO_RS08815	COG1876	peptidase activity
BTOYO_RS08820	COG0824	Thioesterase
BTOYO_RS08825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BTOYO_RS08830	COG1053	succinate dehydrogenase
BTOYO_RS08835	COG2009	succinate dehydrogenase
BTOYO_RS08840	COG1719	4-vinyl reductase, 4VR
BTOYO_RS08850	COG3118	belongs to the thioredoxin family
BTOYO_RS08855	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BTOYO_RS08860	COG2086	electron transfer activity
BTOYO_RS08865	COG1024	Enoyl-CoA hydratase
BTOYO_RS08870	COG1309	transcriptional regulator
BTOYO_RS08875	COG0318	PFAM AMP-dependent synthetase and ligase
BTOYO_RS08905	COG2318	DinB family
BTOYO_RS08930	COG1131	(ABC) transporter
BTOYO_RS08935	COG2205	protein histidine kinase activity
BTOYO_RS08940	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS08950	COG4895	conserved protein (DUF2196)
BTOYO_RS08955	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BTOYO_RS08965	COG4509	Sortase family
BTOYO_RS08970	COG1120	ATPase activity
BTOYO_RS08985	COG5386	Cell surface protein
BTOYO_RS08995	COG5386	Cell surface protein
BTOYO_RS09000	COG1114	Component of the transport system for branched-chain amino acids
BTOYO_RS09005	COG1187	pseudouridine synthase activity
BTOYO_RS09015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTOYO_RS09015	COG1796	DNA polymerase
BTOYO_RS09020	COG1286	toxin biosynthetic process
BTOYO_RS09025	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BTOYO_RS09060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTOYO_RS09070	COG1418	mRNA catabolic process
BTOYO_RS09090	COG1566	PFAM secretion protein HlyD family protein
BTOYO_RS09095	COG1309	transcriptional regulator
BTOYO_RS09100	COG1363	Peptidase, m42
BTOYO_RS09125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTOYO_RS09135	COG1484	DNA-dependent DNA replication
BTOYO_RS09140	COG3611	Membrane attachment protein
BTOYO_RS09150	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BTOYO_RS09155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTOYO_RS09160	COG0237	dephospho-CoA kinase activity
BTOYO_RS09165	COG1971	Probably functions as a manganese efflux pump
BTOYO_RS09175	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTOYO_RS09175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTOYO_RS09180	COG5002	protein histidine kinase activity
BTOYO_RS09185	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS09205	COG0538	isocitrate dehydrogenase activity
BTOYO_RS09210	COG0372	Belongs to the citrate synthase family
BTOYO_RS09220	COG0628	permease
BTOYO_RS09225	COG3030	protein affecting phage T7 exclusion by the F plasmid
BTOYO_RS09250	COG1725	Transcriptional regulator
BTOYO_RS09255	COG0281	malic enzyme
BTOYO_RS09260	COG0587	DNA-directed DNA polymerase activity
BTOYO_RS09275	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BTOYO_RS09290	COG4109	DRTGG domain
BTOYO_RS09305	COG0006	proline dipeptidase activity
BTOYO_RS09340	COG0662	Cupin 2, conserved barrel domain protein
BTOYO_RS09355	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS09360	COG0589	response to stress
BTOYO_RS09365	COG0346	lactoylglutathione lyase activity
BTOYO_RS09405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTOYO_RS09430	COG0827	DNA restriction-modification system
BTOYO_RS09435	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BTOYO_RS09440	COG3874	Sporulation protein YtfJ
BTOYO_RS09455	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BTOYO_RS09465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTOYO_RS09480	COG1104	cysteine desulfurase activity
BTOYO_RS09485	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BTOYO_RS09490	COG0583	DNA-binding transcription factor activity
BTOYO_RS09495	COG0697	spore germination
BTOYO_RS09500	COG1309	transcriptional regulator
BTOYO_RS09505	COG1956	GAF domain-containing protein
BTOYO_RS09510	COG0626	cystathionine gamma-synthase activity
BTOYO_RS09545	COG1595	DNA-templated transcription, initiation
BTOYO_RS09555	COG0110	maltose O-acetyltransferase activity
BTOYO_RS09560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTOYO_RS09565	COG0454	-acetyltransferase
BTOYO_RS09570	COG0517	IMP dehydrogenase activity
BTOYO_RS09575	COG0123	including yeast histone deacetylase and acetoin utilization protein
BTOYO_RS09590	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS09595	COG5002	protein histidine kinase activity
BTOYO_RS09630	COG1609	Transcriptional regulator
BTOYO_RS09635	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTOYO_RS09635	COG1605	Chorismate mutase
BTOYO_RS09640	COG4851	CamS sex pheromone cAM373 precursor
BTOYO_RS09645	COG3118	belongs to the thioredoxin family
BTOYO_RS09655	COG2309	aminopeptidase activity
BTOYO_RS09675	COG0697	spore germination
BTOYO_RS09680	COG0789	Transcriptional regulator
BTOYO_RS09700	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTOYO_RS09700	COG1388	LysM domain
BTOYO_RS09710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTOYO_RS09715	COG4848	Belongs to the UPF0354 family
BTOYO_RS09720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTOYO_RS09725	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BTOYO_RS09730	COG1363	Peptidase, m42
BTOYO_RS09740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTOYO_RS09755	COG0510	thiamine kinase activity
BTOYO_RS09760	COG1523	belongs to the glycosyl hydrolase 13 family
BTOYO_RS09770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTOYO_RS09775	COG1349	DNA-binding transcription factor activity
BTOYO_RS09780	COG1187	pseudouridine synthase activity
BTOYO_RS09785	COG2244	polysaccharide biosynthetic process
BTOYO_RS09790	COG2081	HI0933 family
BTOYO_RS09795	COG2814	Major facilitator Superfamily
BTOYO_RS09805	COG3832	glyoxalase III activity
BTOYO_RS09835	COG1329	Transcriptional regulator
BTOYO_RS09860	COG0314	molybdopterin synthase activity
BTOYO_RS09865	COG1763	Mo-molybdopterin cofactor biosynthetic process
BTOYO_RS09870	COG0303	'Molybdopterin
BTOYO_RS09880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTOYO_RS09885	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTOYO_RS09905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTOYO_RS09915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTOYO_RS09960	COG2814	Major facilitator Superfamily
BTOYO_RS09965	COG0475	glutathione-regulated potassium exporter activity
BTOYO_RS09970	COG0490	domain, Protein
BTOYO_RS09975	COG0582	viral genome integration into host DNA
BTOYO_RS09990	COG1136	(ABC) transporter
BTOYO_RS10010	COG1242	4 iron, 4 sulfur cluster binding
BTOYO_RS10015	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BTOYO_RS10020	COG1794	racemase activity, acting on amino acids and derivatives
BTOYO_RS10035	COG2267	carboxylic ester hydrolase activity
BTOYO_RS10040	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTOYO_RS10045	COG0671	phosphoesterase, PA-phosphatase related
BTOYO_RS10050	COG0438	transferase activity, transferring glycosyl groups
BTOYO_RS10110	COG3852	Histidine kinase
BTOYO_RS10115	COG3852	Histidine kinase
BTOYO_RS10120	COG0753	catalase activity
BTOYO_RS10125	COG2267	carboxylic ester hydrolase activity
BTOYO_RS10130	COG1368	sulfuric ester hydrolase activity
BTOYO_RS10145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTOYO_RS10150	COG1116	anion transmembrane transporter activity
BTOYO_RS10155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTOYO_RS10180	COG0494	nUDIX hydrolase
BTOYO_RS10210	COG2076	Multidrug Resistance protein
BTOYO_RS10215	COG2076	Multidrug Resistance protein
BTOYO_RS10220	COG0789	Transcriptional regulator
BTOYO_RS10225	COG1854	S-ribosylhomocysteine lyase activity
BTOYO_RS10235	COG0288	reversible hydration of carbon dioxide
BTOYO_RS10240	COG1271	oxidase subunit
BTOYO_RS10245	COG1294	oxidase, subunit
BTOYO_RS10260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTOYO_RS10285	COG1842	Phage shock protein A
BTOYO_RS10315	COG5002	protein histidine kinase activity
BTOYO_RS10320	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS10345	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTOYO_RS10350	COG1597	lipid kinase activity
BTOYO_RS10375	COG0577	efflux transmembrane transporter activity
BTOYO_RS10380	COG1136	(ABC) transporter
BTOYO_RS10395	COG0586	Pfam SNARE associated Golgi protein
BTOYO_RS10400	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BTOYO_RS10405	COG0577	efflux transmembrane transporter activity
BTOYO_RS10410	COG1136	(ABC) transporter
BTOYO_RS10415	COG2207	Transcriptional regulator
BTOYO_RS10415	COG3708	Transcriptional regulator
BTOYO_RS10425	COG1131	(ABC) transporter
BTOYO_RS10430	COG5658	integral membrane protein
BTOYO_RS10435	COG0640	Transcriptional regulator
BTOYO_RS10445	COG1595	DNA-templated transcription, initiation
BTOYO_RS10450	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS10455	COG2205	protein histidine kinase activity
BTOYO_RS10460	COG0577	efflux transmembrane transporter activity
BTOYO_RS10465	COG0577	efflux transmembrane transporter activity
BTOYO_RS10470	COG1136	(ABC) transporter
BTOYO_RS10475	COG0577	efflux transmembrane transporter activity
BTOYO_RS10490	COG2188	Transcriptional regulator
BTOYO_RS10510	COG3964	amidohydrolase
BTOYO_RS10525	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS10530	COG4948	Mandelate Racemase Muconate Lactonizing
BTOYO_RS10540	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BTOYO_RS10555	COG1169	isochorismate synthase
BTOYO_RS10560	COG1575	Belongs to the MenA family. Type 1 subfamily
BTOYO_RS10565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BTOYO_RS10570	COG1278	Cold shock
BTOYO_RS10590	COG0058	SHG alpha-glucan phosphorylase activity
BTOYO_RS10600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BTOYO_RS10605	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BTOYO_RS10730	COG0544	peptidyl-prolyl cis-trans isomerase activity
BTOYO_RS10765	COG1285	pathogenesis
BTOYO_RS10770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTOYO_RS10785	COG2155	Conserved Protein
BTOYO_RS10790	COG1098	S1 RNA binding domain
BTOYO_RS10795	COG0436	Aminotransferase
BTOYO_RS10800	COG1522	sequence-specific DNA binding
BTOYO_RS10805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTOYO_RS10810	COG2267	carboxylic ester hydrolase activity
BTOYO_RS10820	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BTOYO_RS10840	COG5018	Exonuclease
BTOYO_RS10845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTOYO_RS10865	COG2050	protein possibly involved in aromatic compounds catabolism
BTOYO_RS10875	COG1268	BioY protein
BTOYO_RS10880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTOYO_RS10885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTOYO_RS10900	COG3584	3D domain protein
BTOYO_RS10915	COG1252	NADH dehydrogenase
BTOYO_RS10925	COG3708	Transcriptional regulator
BTOYO_RS10940	COG1683	Conserved Protein
BTOYO_RS10960	COG0316	Belongs to the HesB IscA family
BTOYO_RS10975	COG1252	NADH dehydrogenase
BTOYO_RS10985	COG2274	protein secretion by the type I secretion system
BTOYO_RS10990	COG0390	transport system, permease component
BTOYO_RS10995	COG2824	Alkylphosphonate utilization operon protein PhnA
BTOYO_RS11025	COG4837	Protein of unknown function (DUF1462)
BTOYO_RS11030	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BTOYO_RS11040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTOYO_RS11045	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BTOYO_RS11065	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTOYO_RS11075	COG0647	UMP catabolic process
BTOYO_RS11085	COG2445	Protein of unknown function DUF86
BTOYO_RS11090	COG1494	fructose-1,6-bisphosphatase
BTOYO_RS11110	COG4470	Protein conserved in bacteria
BTOYO_RS11120	COG0789	Transcriptional regulator
BTOYO_RS11125	COG4377	Putative membrane peptidase family (DUF2324)
BTOYO_RS11150	COG0739	heme binding
BTOYO_RS11160	COG3377	Domain of unknown function (DUF1805)
BTOYO_RS11165	COG0737	Belongs to the 5'-nucleotidase family
BTOYO_RS11170	COG0719	Fe-S assembly protein
BTOYO_RS11175	COG0822	iron-sulfur transferase activity
BTOYO_RS11180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BTOYO_RS11185	COG0719	Fe-S assembly protein
BTOYO_RS11190	COG0396	ATPase activity
BTOYO_RS11195	COG1464	Belongs to the NlpA lipoprotein family
BTOYO_RS11200	COG1464	Belongs to the NlpA lipoprotein family
BTOYO_RS11205	COG2011	ABC-type metal ion transport system permease component
BTOYO_RS11220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTOYO_RS11225	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BTOYO_RS11235	COG1393	Belongs to the ArsC family
BTOYO_RS11255	COG0039	L-malate dehydrogenase activity
BTOYO_RS11275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTOYO_RS11280	COG1960	acyl-CoA dehydrogenase activity
BTOYO_RS11290	COG0183	Belongs to the thiolase family
BTOYO_RS11295	COG1024	Enoyl-CoA hydratase
BTOYO_RS11295	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTOYO_RS11305	COG1686	Belongs to the peptidase S11 family
BTOYO_RS11310	COG0506	proline dehydrogenase activity
BTOYO_RS11320	COG0011	TIGRFAM Protein of
BTOYO_RS11325	COG0840	transmembrane signaling receptor activity
BTOYO_RS11340	COG2814	Major facilitator Superfamily
BTOYO_RS11345	COG0531	amino acid
BTOYO_RS11370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTOYO_RS11400	COG0586	Pfam SNARE associated Golgi protein
BTOYO_RS11410	COG1376	ErfK ybiS ycfS ynhG family protein
BTOYO_RS11415	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS11420	COG5002	protein histidine kinase activity
BTOYO_RS11440	COG0840	transmembrane signaling receptor activity
BTOYO_RS11445	COG0840	transmembrane signaling receptor activity
BTOYO_RS11450	COG2151	metal-sulfur cluster biosynthetic enzyme
BTOYO_RS11455	COG3227	Zinc metalloprotease (Elastase)
BTOYO_RS11475	COG0586	Pfam SNARE associated Golgi protein
BTOYO_RS11480	COG0475	glutathione-regulated potassium exporter activity
BTOYO_RS11485	COG0490	domain, Protein
BTOYO_RS11490	COG1115	amino acid carrier protein
BTOYO_RS11495	COG0783	Belongs to the Dps family
BTOYO_RS11510	COG1611	Belongs to the LOG family
BTOYO_RS11520	COG1528	Iron-storage protein
BTOYO_RS11525	COG2311	Membrane
BTOYO_RS11530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTOYO_RS11535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTOYO_RS11540	COG1115	amino acid carrier protein
BTOYO_RS11545	COG1115	amino acid carrier protein
BTOYO_RS11550	COG2910	NAD(P)H-binding
BTOYO_RS11565	COG0656	L-ascorbic acid biosynthetic process
BTOYO_RS11570	COG2814	Major facilitator Superfamily
BTOYO_RS11575	COG1733	regulation of RNA biosynthetic process
BTOYO_RS11585	COG1252	NADH dehydrogenase
BTOYO_RS11590	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BTOYO_RS11605	COG3290	protein histidine kinase activity
BTOYO_RS11605	COG0840	transmembrane signaling receptor activity
BTOYO_RS11615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BTOYO_RS11640	COG0488	(ABC) transporter
BTOYO_RS11645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTOYO_RS11660	COG1335	isochorismatase
BTOYO_RS11665	COG1522	sequence-specific DNA binding
BTOYO_RS11675	COG1522	sequence-specific DNA binding
BTOYO_RS11680	COG0288	reversible hydration of carbon dioxide
BTOYO_RS11685	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BTOYO_RS11690	COG2233	PERMEase
BTOYO_RS11735	COG0557	exoribonuclease II activity
BTOYO_RS11740	COG1647	Serine aminopeptidase, S33
BTOYO_RS11745	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTOYO_RS11750	COG1346	cytolysis
BTOYO_RS11785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTOYO_RS11800	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BTOYO_RS11835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTOYO_RS11850	COG2323	membrane
BTOYO_RS11860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTOYO_RS11870	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BTOYO_RS11880	COG1051	belongs to the nudix hydrolase family
BTOYO_RS11890	COG0492	ferredoxin-NADP+ reductase activity
BTOYO_RS11895	COG0457	Tetratricopeptide repeat
BTOYO_RS11900	COG0110	maltose O-acetyltransferase activity
BTOYO_RS11920	COG1950	PFAM Membrane protein of
BTOYO_RS11930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BTOYO_RS11935	COG0556	nucleotide-excision repair
BTOYO_RS11950	COG0789	Transcriptional regulator
BTOYO_RS11975	COG0583	DNA-binding transcription factor activity
BTOYO_RS11980	COG0789	Transcriptional regulator
BTOYO_RS11985	COG0655	NAD(P)H dehydrogenase (quinone) activity
BTOYO_RS11990	COG0488	(ABC) transporter
BTOYO_RS12000	COG1132	(ABC) transporter
BTOYO_RS12005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTOYO_RS12010	COG0793	Belongs to the peptidase S41A family
BTOYO_RS12010	COG3409	Peptidoglycan-binding domain 1 protein
BTOYO_RS12015	COG2177	Part of the ABC transporter FtsEX involved in
BTOYO_RS12020	COG2884	Cell division ATP-binding protein ftsE
BTOYO_RS12030	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BTOYO_RS12040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BTOYO_RS12045	COG1278	Cold shock
BTOYO_RS12050	COG1040	competence protein
BTOYO_RS12055	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BTOYO_RS12060	COG0791	NLP P60 protein
BTOYO_RS12060	COG1388	LysM domain
BTOYO_RS12065	COG1733	regulation of RNA biosynthetic process
BTOYO_RS12070	COG1307	EDD domain protein, DegV family
BTOYO_RS12080	COG1316	TRANSCRIPTIONal
BTOYO_RS12085	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BTOYO_RS12090	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BTOYO_RS12095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTOYO_RS12105	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BTOYO_RS12105	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BTOYO_RS12125	COG1486	melibiose metabolic process
BTOYO_RS12130	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTOYO_RS12135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTOYO_RS12145	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BTOYO_RS12155	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTOYO_RS12165	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTOYO_RS12170	COG1301	dicarboxylic acid transport
BTOYO_RS12180	COG0346	lactoylglutathione lyase activity
BTOYO_RS12185	COG1511	domain protein
BTOYO_RS12190	COG0583	DNA-binding transcription factor activity
BTOYO_RS12195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BTOYO_RS12205	COG1271	oxidase subunit
BTOYO_RS12210	COG1294	oxidase, subunit
BTOYO_RS12215	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTOYO_RS12225	COG1620	l-lactate permease
BTOYO_RS12235	COG2389	metal-binding protein
BTOYO_RS12245	COG1368	sulfuric ester hydrolase activity
BTOYO_RS12255	COG0791	NLP P60 protein
BTOYO_RS12255	COG1388	LysM domain
BTOYO_RS12260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTOYO_RS12270	COG1215	transferase activity, transferring glycosyl groups
BTOYO_RS12280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTOYO_RS12285	COG3584	3D domain protein
BTOYO_RS12285	COG1388	LysM domain
BTOYO_RS12295	COG4715	Zinc finger, swim domain protein
BTOYO_RS12300	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTOYO_RS12340	COG0577	efflux transmembrane transporter activity
BTOYO_RS12345	COG1136	(ABC) transporter
BTOYO_RS12370	COG5002	protein histidine kinase activity
BTOYO_RS12370	COG3850	Histidine kinase
BTOYO_RS12375	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS12380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTOYO_RS12385	COG4750	Nucleotidyl transferase
BTOYO_RS12390	COG0697	spore germination
BTOYO_RS12400	COG3475	LICD family
BTOYO_RS12410	COG1316	TRANSCRIPTIONal
BTOYO_RS12425	COG1216	Glycosyl transferase, family 2
BTOYO_RS12425	COG0463	Glycosyl transferase, family 2
BTOYO_RS12460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTOYO_RS12465	COG4464	protein tyrosine phosphatase activity
BTOYO_RS12470	COG0489	protein tyrosine kinase activity
BTOYO_RS12475	COG3944	biosynthesis protein
BTOYO_RS12480	COG0489	protein tyrosine kinase activity
BTOYO_RS12495	COG1609	Transcriptional regulator
BTOYO_RS12505	COG0739	heme binding
BTOYO_RS12520	COG3279	Response regulator of the LytR AlgR family
BTOYO_RS12525	COG2385	sporulation resulting in formation of a cellular spore
BTOYO_RS12540	COG4836	Membrane
BTOYO_RS12545	COG1007	ATP synthesis coupled electron transport
BTOYO_RS12550	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTOYO_RS12555	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTOYO_RS12565	COG0839	Belongs to the complex I subunit 6 family
BTOYO_RS12585	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTOYO_RS12630	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BTOYO_RS12650	COG0356	it plays a direct role in the translocation of protons across the membrane
BTOYO_RS12685	COG0698	ribose 5-phosphate isomerase
BTOYO_RS12695	COG2190	(PTS) system
BTOYO_RS12700	COG2259	Doxx family
BTOYO_RS12705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTOYO_RS12720	COG0009	L-threonylcarbamoyladenylate synthase
BTOYO_RS12740	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BTOYO_RS12755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BTOYO_RS12760	COG1494	fructose-1,6-bisphosphatase
BTOYO_RS12780	COG4821	SIS domain
BTOYO_RS12785	COG0504	CTP synthase activity
BTOYO_RS12800	COG1960	acyl-CoA dehydrogenase activity
BTOYO_RS12805	COG1960	acyl-CoA dehydrogenase activity
BTOYO_RS12810	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTOYO_RS12815	COG0183	Belongs to the thiolase family
BTOYO_RS12820	COG2181	nitrate reductase activity
BTOYO_RS12820	COG0247	lactate metabolic process
BTOYO_RS12825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTOYO_RS12835	COG5001	Diguanylate cyclase
BTOYO_RS12835	COG3300	MHYT domain
BTOYO_RS12850	COG3227	Zinc metalloprotease (Elastase)
BTOYO_RS12855	COG2197	response regulator
BTOYO_RS12860	COG4585	Histidine kinase
BTOYO_RS12865	COG0842	Transport permease protein
BTOYO_RS12870	COG1131	(ABC) transporter
BTOYO_RS12875	COG0024	Methionine aminopeptidase
BTOYO_RS12880	COG2234	aminopeptidase activity
BTOYO_RS12895	COG4506	Protein conserved in bacteria
BTOYO_RS12900	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTOYO_RS12920	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BTOYO_RS12925	COG2814	Major facilitator Superfamily
BTOYO_RS12930	COG0789	Transcriptional regulator
BTOYO_RS12935	COG0584	glycerophosphoryl diester phosphodiesterase
BTOYO_RS12940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTOYO_RS12950	COG1994	Peptidase M50
BTOYO_RS12960	COG1078	dGTPase activity
BTOYO_RS12965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTOYO_RS12970	COG1120	ATPase activity
BTOYO_RS12975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTOYO_RS12980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTOYO_RS12985	COG4844	belongs to the
BTOYO_RS13000	COG0280	phosphate acetyltransferase
BTOYO_RS13015	COG3773	Cell wall hydrolase
BTOYO_RS13025	COG2363	Small membrane protein
BTOYO_RS13035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTOYO_RS13040	COG2233	PERMEase
BTOYO_RS13045	COG0561	phosphatase activity
BTOYO_RS13050	COG2814	Major facilitator Superfamily
BTOYO_RS13060	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BTOYO_RS13065	COG1131	(ABC) transporter
BTOYO_RS13070	COG2755	lipolytic protein G-D-S-L family
BTOYO_RS13075	COG1609	Transcriptional regulator
BTOYO_RS13085	COG0460	homoserine dehydrogenase
BTOYO_RS13095	COG2873	o-acetylhomoserine
BTOYO_RS13105	COG1011	Hydrolase
BTOYO_RS13110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTOYO_RS13120	COG2197	response regulator
BTOYO_RS13125	COG2203	Gaf domain
BTOYO_RS13125	COG4585	Histidine kinase
BTOYO_RS13130	COG0351	phosphomethylpyrimidine kinase
BTOYO_RS13135	COG3706	GGDEF domain
BTOYO_RS13140	COG2879	small protein
BTOYO_RS13145	COG1966	Carbon starvation protein
BTOYO_RS13150	COG3279	Response regulator of the LytR AlgR family
BTOYO_RS13155	COG0477	Major facilitator Superfamily
BTOYO_RS13165	COG0438	transferase activity, transferring glycosyl groups
BTOYO_RS13180	COG0840	transmembrane signaling receptor activity
BTOYO_RS13190	COG1607	acyl-coa hydrolase
BTOYO_RS13200	COG1215	transferase activity, transferring glycosyl groups
BTOYO_RS13210	COG1309	transcriptional regulator
BTOYO_RS13215	COG0488	(ABC) transporter
BTOYO_RS13235	COG0463	Glycosyl transferase, family 2
BTOYO_RS13240	COG1309	transcriptional regulator
BTOYO_RS13245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTOYO_RS13250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTOYO_RS13250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTOYO_RS13255	COG0628	permease
BTOYO_RS13275	COG3275	phosphorelay sensor kinase activity
BTOYO_RS13280	COG2814	Major facilitator Superfamily
BTOYO_RS13285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTOYO_RS13290	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BTOYO_RS13315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTOYO_RS13320	COG1272	protein, Hemolysin III
BTOYO_RS13345	COG1164	Oligoendopeptidase f
BTOYO_RS13365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTOYO_RS13370	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BTOYO_RS13375	COG4853	Protein conserved in bacteria
BTOYO_RS13385	COG5002	protein histidine kinase activity
BTOYO_RS13390	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS13420	COG0305	Participates in initiation and elongation during chromosome replication
BTOYO_RS13430	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BTOYO_RS13435	COG4241	membrane
BTOYO_RS13445	COG0629	single-stranded DNA binding
BTOYO_RS13455	COG0012	GTP binding
BTOYO_RS13460	COG4481	Protein conserved in bacteria
BTOYO_RS13465	COG0668	transmembrane transport
BTOYO_RS13475	COG1475	DNA binding
BTOYO_RS13480	COG1192	Involved in chromosome partitioning
BTOYO_RS13510	COG0706	membrane insertase activity
BTOYO_RS13520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BTOYO_RS13530	COG0592	DNA-directed DNA polymerase activity
BTOYO_RS13535	COG2501	S4 domain
BTOYO_RS13545	COG0187	DNA topoisomerase II activity
BTOYO_RS13550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTOYO_RS13585	COG0517	IMP dehydrogenase activity
BTOYO_RS13585	COG0516	GMP reductase activity
BTOYO_RS13590	COG1686	Belongs to the peptidase S11 family
BTOYO_RS13620	COG1428	Deoxynucleoside kinase
BTOYO_RS13625	COG1428	Deoxynucleoside kinase
BTOYO_RS13630	COG1335	isochorismatase
BTOYO_RS13635	COG0590	tRNA wobble adenosine to inosine editing
BTOYO_RS13640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTOYO_RS13695	COG1982	Orn Lys Arg decarboxylase major
BTOYO_RS13705	COG0470	DNA polymerase III
BTOYO_RS13710	COG1774	PSP1 C-terminal conserved region
BTOYO_RS13720	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BTOYO_RS13730	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BTOYO_RS13735	COG2002	toxin-antitoxin pair type II binding
BTOYO_RS13745	COG0084	hydrolase, TatD family'
BTOYO_RS13755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BTOYO_RS13765	COG4466	Protein conserved in bacteria
BTOYO_RS13780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BTOYO_RS13785	COG0251	oxidation-reduction process
BTOYO_RS13790	COG2088	sporulation resulting in formation of a cellular spore
BTOYO_RS13815	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTOYO_RS13820	COG2002	toxin-antitoxin pair type II binding
BTOYO_RS13825	COG2244	polysaccharide biosynthetic process
BTOYO_RS13830	COG3956	TIGRFAM MazG family protein
BTOYO_RS13835	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BTOYO_RS13855	COG1098	S1 RNA binding domain
BTOYO_RS13870	COG2208	phosphoserine phosphatase activity
BTOYO_RS13880	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTOYO_RS13885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTOYO_RS13900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTOYO_RS13905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BTOYO_RS13910	COG0512	Glutamine amidotransferase of anthranilate synthase
BTOYO_RS13915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTOYO_RS13920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BTOYO_RS13925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BTOYO_RS13930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BTOYO_RS13935	COG1396	sequence-specific DNA binding
BTOYO_RS13940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTOYO_RS13970	COG3880	PFAM UvrB UvrC protein
BTOYO_RS13980	COG0542	response to heat
BTOYO_RS13985	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BTOYO_RS13995	COG4956	integral membrane protein (PIN domain superfamily)
BTOYO_RS14015	COG1045	serine acetyltransferase
BTOYO_RS14030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTOYO_RS14035	COG3688	RNA-binding protein containing a PIN domain
BTOYO_RS14045	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTOYO_RS14050	COG0250	Participates in transcription elongation, termination and antitermination
BTOYO_RS14055	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BTOYO_RS14060	COG0081	regulation of translation
BTOYO_RS14070	COG0222	ribosome binding
BTOYO_RS14075	COG2813	Specifically methylates the guanine in position
BTOYO_RS14090	COG1358	cellular component organization or biogenesis
BTOYO_RS14095	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BTOYO_RS14115	COG0051	transcription antitermination factor activity, RNA binding
BTOYO_RS14120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BTOYO_RS14160	COG0255	Belongs to the universal ribosomal protein uL29 family
BTOYO_RS14210	COG1841	ribosomal large subunit assembly
BTOYO_RS14220	COG0201	protein transport
BTOYO_RS14230	COG0024	Methionine aminopeptidase
BTOYO_RS14240	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BTOYO_RS14275	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BTOYO_RS14305	COG0489	protein tyrosine kinase activity
BTOYO_RS14315	COG2194	sulfuric ester hydrolase activity
BTOYO_RS14320	COG0726	polysaccharide deacetylase
BTOYO_RS14400	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BTOYO_RS14405	COG4856	YbbR-like protein
BTOYO_RS14440	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS14445	COG2011	ABC-type metal ion transport system permease component
BTOYO_RS14455	COG1464	Belongs to the NlpA lipoprotein family
BTOYO_RS14460	COG0604	alcohol dehydrogenase
BTOYO_RS14470	COG0277	FAD linked oxidase domain protein
BTOYO_RS14475	COG2271	Major facilitator Superfamily
BTOYO_RS14485	COG2814	Major facilitator Superfamily
BTOYO_RS14500	COG0601	transmembrane transport
BTOYO_RS14505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTOYO_RS14510	COG0444	Belongs to the ABC transporter superfamily
BTOYO_RS14515	COG4608	Belongs to the ABC transporter superfamily
BTOYO_RS14520	COG4166	transmembrane transport
BTOYO_RS14530	COG2207	Transcriptional regulator
BTOYO_RS14540	COG4166	transmembrane transport
BTOYO_RS14545	COG4166	transmembrane transport
BTOYO_RS14550	COG0656	L-ascorbic acid biosynthetic process
BTOYO_RS14570	COG4149	molybdate abc transporter
BTOYO_RS14575	COG0725	ABC transporter, periplasmic molybdate-binding protein
BTOYO_RS14580	COG1910	domain protein
BTOYO_RS14590	COG0697	spore germination
BTOYO_RS14600	COG0204	Acyl-transferase
BTOYO_RS14605	COG1609	Transcriptional regulator
BTOYO_RS14615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTOYO_RS14635	COG5298	Protein conserved in bacteria
BTOYO_RS14665	COG0747	negative chemotaxis
BTOYO_RS14670	COG0601	transmembrane transport
BTOYO_RS14675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTOYO_RS14680	COG0444	Belongs to the ABC transporter superfamily
BTOYO_RS14685	COG4608	Belongs to the ABC transporter superfamily
BTOYO_RS14690	COG0561	phosphatase activity
BTOYO_RS14720	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BTOYO_RS14725	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTOYO_RS14735	COG0531	amino acid
BTOYO_RS14740	COG2814	Major facilitator Superfamily
BTOYO_RS14750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BTOYO_RS14760	COG4294	response to UV
BTOYO_RS14765	COG0705	Rhomboid family
BTOYO_RS14775	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BTOYO_RS14780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTOYO_RS14785	COG0864	Transcriptional regulator
BTOYO_RS14790	COG2337	Toxic component of a toxin-antitoxin (TA) module
BTOYO_RS14795	COG2183	response to ionizing radiation
BTOYO_RS14890	COG0802	atpase or kinase
BTOYO_RS14895	COG1214	PFAM Peptidase M22, glycoprotease
BTOYO_RS14900	COG0456	acetyltransferase
BTOYO_RS14910	COG0488	(ABC) transporter
BTOYO_RS14925	COG1266	CAAX protease self-immunity
BTOYO_RS14935	COG0459	protein refolding
BTOYO_RS14950	COG2252	PERMEase
BTOYO_RS14960	COG5002	protein histidine kinase activity
BTOYO_RS15000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTOYO_RS15010	COG1215	transferase activity, transferring glycosyl groups
BTOYO_RS15030	COG0697	spore germination
BTOYO_RS15080	COG2205	protein histidine kinase activity
BTOYO_RS15085	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS15110	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTOYO_RS15115	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BTOYO_RS15120	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTOYO_RS15130	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTOYO_RS15145	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BTOYO_RS15155	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BTOYO_RS15160	COG0138	bifunctional purine biosynthesis protein purh
BTOYO_RS15165	COG0151	Belongs to the GarS family
BTOYO_RS15190	COG0210	DNA helicase
BTOYO_RS15200	COG4851	CamS sex pheromone cAM373 precursor
BTOYO_RS15215	COG1335	isochorismatase
BTOYO_RS15225	COG2011	ABC-type metal ion transport system permease component
BTOYO_RS15230	COG1464	Belongs to the NlpA lipoprotein family
BTOYO_RS15240	COG0003	Pfam Anion-transporting ATPase
BTOYO_RS15245	COG1846	Transcriptional regulator
BTOYO_RS15250	COG4682	membrane
BTOYO_RS15270	COG1597	lipid kinase activity
BTOYO_RS15275	COG0546	phosphoglycolate phosphatase activity
BTOYO_RS15280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTOYO_RS15290	COG1012	belongs to the aldehyde dehydrogenase family
BTOYO_RS15295	COG2076	Multidrug Resistance protein
BTOYO_RS15305	COG2309	aminopeptidase activity
BTOYO_RS15320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTOYO_RS15330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTOYO_RS15335	COG5002	protein histidine kinase activity
BTOYO_RS15345	COG4807	Protein conserved in bacteria
BTOYO_RS15370	COG1757	Na H antiporter
BTOYO_RS15375	COG1473	amidohydrolase
BTOYO_RS15390	COG0450	alkyl hydroperoxide reductase
BTOYO_RS15410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTOYO_RS15415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTOYO_RS15420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTOYO_RS15425	COG0492	ferredoxin-NADP+ reductase activity
BTOYO_RS15435	COG0166	Belongs to the GPI family
BTOYO_RS15460	COG5002	protein histidine kinase activity
BTOYO_RS15480	COG3541	Predicted nucleotidyltransferase
BTOYO_RS15485	COG2814	Major facilitator Superfamily
BTOYO_RS15490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTOYO_RS15490	COG0723	plastoquinol--plastocyanin reductase activity
BTOYO_RS15500	COG0765	amino acid transport
BTOYO_RS15505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTOYO_RS15515	COG0840	transmembrane signaling receptor activity
BTOYO_RS15540	COG0549	Belongs to the carbamate kinase family
BTOYO_RS15555	COG0277	FAD linked oxidase domain protein
BTOYO_RS15560	COG0366	Alpha amylase catalytic
BTOYO_RS15565	COG2190	(PTS) system
BTOYO_RS15565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTOYO_RS15565	COG1263	PTS System
BTOYO_RS15595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTOYO_RS15600	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BTOYO_RS15620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTOYO_RS15630	COG1116	anion transmembrane transporter activity
BTOYO_RS15675	COG2270	Major facilitator Superfamily
BTOYO_RS15700	COG4193	domain, Protein
BTOYO_RS15710	COG2310	stress, protein
BTOYO_RS15715	COG2310	stress, protein
BTOYO_RS15720	COG2310	stress, protein
BTOYO_RS15725	COG0861	Integral membrane protein TerC family
BTOYO_RS15735	COG3853	Toxic anion resistance protein (TelA)
BTOYO_RS15750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BTOYO_RS15760	COG1295	ribonuclease BN
BTOYO_RS15765	COG2217	Heavy metal translocating P-type atpase
BTOYO_RS15770	COG0697	spore germination
BTOYO_RS15790	COG0586	Pfam SNARE associated Golgi protein
BTOYO_RS15805	COG3871	stress protein (general stress protein 26)
BTOYO_RS15810	COG0387	Pfam Sodium calcium exchanger
BTOYO_RS15820	COG0535	radical SAM domain protein
BTOYO_RS15840	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BTOYO_RS15870	COG0833	amino acid
BTOYO_RS15875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTOYO_RS15900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTOYO_RS15900	COG1263	PTS System
BTOYO_RS15905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTOYO_RS15925	COG0463	Glycosyl transferase, family 2
BTOYO_RS15935	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTOYO_RS15935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTOYO_RS15945	COG1882	Formate acetyltransferase
BTOYO_RS15950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BTOYO_RS15970	COG1228	amidohydrolase
BTOYO_RS15975	COG1090	epimerase
BTOYO_RS16005	COG1988	membrane-bound metal-dependent
BTOYO_RS16010	COG1194	a g-specific adenine glycosylase
BTOYO_RS16030	COG3557	Belongs to the UPF0374 family
BTOYO_RS16035	COG1132	(ABC) transporter
BTOYO_RS16040	COG4129	membrane
BTOYO_RS16045	COG0069	glutamate synthase activity
BTOYO_RS16045	COG0067	glutamate synthase
BTOYO_RS16045	COG0070	glutamate synthase
BTOYO_RS16050	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BTOYO_RS16055	COG4555	ABC transporter
BTOYO_RS16075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTOYO_RS16080	COG0735	belongs to the Fur family
BTOYO_RS16200	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BTOYO_RS16225	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BTOYO_RS16230	COG5001	Diguanylate cyclase
BTOYO_RS16230	COG1716	ATPase activity
BTOYO_RS16235	COG2766	serine protein kinase
BTOYO_RS16240	COG2718	Belongs to the UPF0229 family
BTOYO_RS16255	COG1585	Membrane protein implicated in regulation of membrane protease activity
BTOYO_RS16260	COG2268	Band 7 protein
BTOYO_RS16270	COG3290	protein histidine kinase activity
BTOYO_RS16275	COG4565	transcriptional regulatory protein
BTOYO_RS16280	COG2851	Citrate transporter
BTOYO_RS16305	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BTOYO_RS16310	COG3842	ATPase activity
BTOYO_RS16315	COG1175	transmembrane transport
BTOYO_RS16320	COG0395	ABC-type sugar transport system, permease component
BTOYO_RS16330	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BTOYO_RS16335	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS16340	COG5002	protein histidine kinase activity
BTOYO_RS16350	COG4990	cell redox homeostasis
BTOYO_RS16360	COG3290	protein histidine kinase activity
BTOYO_RS16365	COG4565	transcriptional regulatory protein
BTOYO_RS16370	COG3493	citrate carrier protein
BTOYO_RS16375	COG0281	malic enzyme
BTOYO_RS16385	COG0697	spore germination
BTOYO_RS16390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTOYO_RS16400	COG5002	protein histidine kinase activity
BTOYO_RS16405	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS16415	COG0456	acetyltransferase
BTOYO_RS16415	COG0454	-acetyltransferase
BTOYO_RS16420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTOYO_RS16425	COG3383	formate dehydrogenase (NAD+) activity
BTOYO_RS16430	COG2427	Protein of unknown function (DUF1641)
BTOYO_RS16445	COG0531	amino acid
BTOYO_RS16455	COG0640	Transcriptional regulator
BTOYO_RS16460	COG2217	Heavy metal translocating P-type atpase
BTOYO_RS16465	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BTOYO_RS16475	COG3227	Zinc metalloprotease (Elastase)
BTOYO_RS16495	COG2720	vancomycin resistance protein
BTOYO_RS16500	COG1316	TRANSCRIPTIONal
BTOYO_RS16505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTOYO_RS16510	COG0346	lactoylglutathione lyase activity
BTOYO_RS16515	COG1253	flavin adenine dinucleotide binding
BTOYO_RS16520	COG1027	Aspartate ammonia-lyase
BTOYO_RS16525	COG1620	l-lactate permease
BTOYO_RS16540	COG3104	oligopeptide transport
BTOYO_RS16545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTOYO_RS16550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTOYO_RS16555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTOYO_RS16565	COG2226	methyltransferase
BTOYO_RS16575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTOYO_RS16585	COG4548	von Willebrand factor, type A
BTOYO_RS16590	COG0714	Associated with various cellular activities
BTOYO_RS16610	COG0531	amino acid
BTOYO_RS16615	COG2188	Transcriptional regulator
BTOYO_RS16620	COG1263	PTS System
BTOYO_RS16620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTOYO_RS16625	COG0366	Alpha amylase catalytic
BTOYO_RS16640	COG0697	spore germination
BTOYO_RS16650	COG4585	Histidine kinase
BTOYO_RS16655	COG2197	response regulator
BTOYO_RS16660	COG1404	Belongs to the peptidase S8 family
BTOYO_RS16670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTOYO_RS16675	COG1115	amino acid carrier protein
BTOYO_RS16680	COG1126	abc transporter atp-binding protein
BTOYO_RS16685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTOYO_RS16690	COG0765	amino acid transport
BTOYO_RS16695	COG0765	amino acid transport
BTOYO_RS16700	COG0833	amino acid
BTOYO_RS16725	COG2378	regulation of single-species biofilm formation
BTOYO_RS16730	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BTOYO_RS16735	COG5002	protein histidine kinase activity
BTOYO_RS16750	COG0659	secondary active sulfate transmembrane transporter activity
BTOYO_RS16765	COG2271	Major facilitator Superfamily
BTOYO_RS16770	COG1846	Transcriptional regulator
BTOYO_RS16775	COG0477	Major facilitator Superfamily
BTOYO_RS16780	COG1609	Transcriptional regulator
BTOYO_RS16785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTOYO_RS16800	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTOYO_RS16805	COG1879	ABC-type sugar transport system periplasmic component
BTOYO_RS16830	COG1063	alcohol dehydrogenase
BTOYO_RS16880	COG0840	transmembrane signaling receptor activity
BTOYO_RS16885	COG3584	3D domain protein
BTOYO_RS16885	COG1388	LysM domain
BTOYO_RS16890	COG1476	TRANSCRIPTIONal
BTOYO_RS16915	COG1114	Component of the transport system for branched-chain amino acids
BTOYO_RS16930	COG1113	amino acid transport
BTOYO_RS16935	COG2252	PERMEase
BTOYO_RS16955	COG0475	glutathione-regulated potassium exporter activity
BTOYO_RS16955	COG0569	domain protein
BTOYO_RS16965	COG1845	cytochrome c oxidase, subunit III
BTOYO_RS16970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTOYO_RS16975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BTOYO_RS16980	COG0833	amino acid
BTOYO_RS16985	COG4990	cell redox homeostasis
BTOYO_RS17000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTOYO_RS17005	COG0697	spore germination
BTOYO_RS17010	COG0531	amino acid
BTOYO_RS17020	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTOYO_RS17025	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTOYO_RS17030	COG1918	ferrous iron import across plasma membrane
BTOYO_RS17030	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTOYO_RS17035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BTOYO_RS17040	COG0573	inorganic phosphate transmembrane transporter activity
BTOYO_RS17045	COG0581	inorganic phosphate transmembrane transporter activity
BTOYO_RS17050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTOYO_RS17175	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BTOYO_RS17195	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BTOYO_RS17200	COG1116	anion transmembrane transporter activity
BTOYO_RS17205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTOYO_RS17210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTOYO_RS17215	COG0352	thiamine-phosphate diphosphorylase activity
BTOYO_RS17220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTOYO_RS17225	COG2104	thiamine diphosphate biosynthetic process
BTOYO_RS17230	COG2022	thiamine diphosphate biosynthetic process
BTOYO_RS17235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTOYO_RS17240	COG0351	phosphomethylpyrimidine kinase
BTOYO_RS17265	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BTOYO_RS17270	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BTOYO_RS17275	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BTOYO_RS17280	COG2205	protein histidine kinase activity
BTOYO_RS17285	COG2814	Major facilitator Superfamily
BTOYO_RS17290	COG1846	Transcriptional regulator
BTOYO_RS17305	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTOYO_RS17310	COG1129	ABC transporter
BTOYO_RS17320	COG2252	PERMEase
BTOYO_RS17325	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS17385	COG0778	Nitroreductase
BTOYO_RS17390	COG2719	SpoVR family
BTOYO_RS17415	COG1937	Protein conserved in bacteria
BTOYO_RS17420	COG0425	Belongs to the sulfur carrier protein TusA family
BTOYO_RS17420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTOYO_RS17425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTOYO_RS17425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTOYO_RS17430	COG0425	Belongs to the sulfur carrier protein TusA family
BTOYO_RS17435	COG0425	Belongs to the sulfur carrier protein TusA family
BTOYO_RS17435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTOYO_RS17440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTOYO_RS17445	COG2210	Belongs to the sulfur carrier protein TusA family
BTOYO_RS17450	COG0730	response to heat
BTOYO_RS17460	COG1316	TRANSCRIPTIONal
BTOYO_RS17465	COG0604	alcohol dehydrogenase
BTOYO_RS17470	COG1283	sodium-dependent phosphate transmembrane transporter activity
BTOYO_RS17475	COG2814	Major facilitator Superfamily
BTOYO_RS17485	COG3711	transcriptional antiterminator
BTOYO_RS17485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTOYO_RS17490	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTOYO_RS17495	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTOYO_RS17515	COG1388	LysM domain
BTOYO_RS17515	COG3584	3D domain protein
BTOYO_RS17520	COG0577	efflux transmembrane transporter activity
BTOYO_RS17525	COG1136	(ABC) transporter
BTOYO_RS17535	COG5522	Integral membrane protein (intg_mem_TP0381)
BTOYO_RS17550	COG1114	Component of the transport system for branched-chain amino acids
BTOYO_RS17555	COG3546	catalase activity
BTOYO_RS17590	COG0586	Pfam SNARE associated Golgi protein
BTOYO_RS17625	COG0531	amino acid
BTOYO_RS17630	COG0475	glutathione-regulated potassium exporter activity
BTOYO_RS17640	COG1737	Transcriptional regulator
BTOYO_RS17650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTOYO_RS17650	COG1263	PTS System
BTOYO_RS17660	COG2259	Doxx family
BTOYO_RS17680	COG1522	sequence-specific DNA binding
BTOYO_RS17710	COG2076	Multidrug Resistance protein
BTOYO_RS17715	COG1309	transcriptional regulator
BTOYO_RS17720	COG2814	Major facilitator Superfamily
BTOYO_RS17725	COG1733	regulation of RNA biosynthetic process
BTOYO_RS17735	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTOYO_RS17745	COG4533	DNA binding
BTOYO_RS17750	COG2814	Major facilitator Superfamily
BTOYO_RS17760	COG0693	protein deglycase activity
BTOYO_RS17770	COG0531	amino acid
BTOYO_RS17775	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BTOYO_RS17780	COG1012	belongs to the aldehyde dehydrogenase family
BTOYO_RS17785	COG1132	(ABC) transporter
BTOYO_RS17790	COG1132	(ABC) transporter
BTOYO_RS17795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTOYO_RS17800	COG0765	amino acid transport
BTOYO_RS17805	COG1126	abc transporter atp-binding protein
BTOYO_RS17820	COG0189	ligase activity
BTOYO_RS17840	COG0028	Belongs to the TPP enzyme family
BTOYO_RS17845	COG3527	Alpha-acetolactate decarboxylase
BTOYO_RS17855	COG0561	phosphatase activity
BTOYO_RS17865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTOYO_RS17880	COG0659	secondary active sulfate transmembrane transporter activity
BTOYO_RS17890	COG1024	Enoyl-CoA hydratase
BTOYO_RS17910	COG1363	Peptidase, m42
BTOYO_RS17940	COG0579	oxidoreductase
BTOYO_RS17960	COG0601	transmembrane transport
BTOYO_RS17965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTOYO_RS17970	COG0444	Belongs to the ABC transporter superfamily
BTOYO_RS17975	COG4608	Belongs to the ABC transporter superfamily
BTOYO_RS18085	COG0477	Major facilitator Superfamily
BTOYO_RS18090	COG3290	protein histidine kinase activity
BTOYO_RS18095	COG4565	transcriptional regulatory protein
BTOYO_RS18100	COG3181	Tripartite tricarboxylate transporter family receptor
BTOYO_RS18155	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BTOYO_RS18170	COG1204	response to ionizing radiation
BTOYO_RS18185	COG0305	Participates in initiation and elongation during chromosome replication
BTOYO_RS18190	COG1012	belongs to the aldehyde dehydrogenase family
BTOYO_RS18205	COG0477	Major facilitator Superfamily
BTOYO_RS18240	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTOYO_RS18240	COG3409	Peptidoglycan-binding domain 1 protein
BTOYO_RS18250	COG3711	transcriptional antiterminator
BTOYO_RS18255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTOYO_RS18255	COG2190	(PTS) system
BTOYO_RS18255	COG1263	PTS System
BTOYO_RS18260	COG2723	6-phospho-beta-galactosidase activity
BTOYO_RS18270	COG1183	phosphatidylcholine synthase activity
BTOYO_RS18290	COG2814	Major facilitator Superfamily
BTOYO_RS18295	COG0640	Transcriptional regulator
BTOYO_RS18305	COG2376	Dihydroxyacetone kinase
BTOYO_RS18325	COG1959	2 iron, 2 sulfur cluster binding
BTOYO_RS18340	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS18345	COG5002	protein histidine kinase activity
BTOYO_RS18345	COG3850	Histidine kinase
BTOYO_RS18385	COG3237	CsbD-like
BTOYO_RS18410	COG1191	sigma factor activity
BTOYO_RS18420	COG2208	phosphoserine phosphatase activity
BTOYO_RS18425	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTOYO_RS18430	COG2205	protein histidine kinase activity
BTOYO_RS18430	COG2198	Histidine kinase
BTOYO_RS18430	COG0784	Response regulator, receiver
BTOYO_RS18455	COG2807	transmembrane transport
BTOYO_RS18460	COG2186	Transcriptional regulator
BTOYO_RS18495	COG0420	3'-5' exonuclease activity
BTOYO_RS18500	COG4717	serine-type aminopeptidase activity
BTOYO_RS18515	COG0714	Associated with various cellular activities
BTOYO_RS18520	COG0346	lactoylglutathione lyase activity
BTOYO_RS18525	COG0346	lactoylglutathione lyase activity
BTOYO_RS18530	COG0457	Tetratricopeptide repeat
BTOYO_RS18540	COG2267	carboxylic ester hydrolase activity
BTOYO_RS18550	COG3620	sequence-specific DNA binding
BTOYO_RS18555	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BTOYO_RS18560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BTOYO_RS18570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BTOYO_RS18585	COG0772	Belongs to the SEDS family
BTOYO_RS18595	COG3973	AAA domain
BTOYO_RS18600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTOYO_RS18625	COG0537	adenosine 5'-monophosphoramidase activity
BTOYO_RS18630	COG1131	(ABC) transporter
BTOYO_RS18635	COG4473	ABC transporter
BTOYO_RS18650	COG1309	transcriptional regulator
BTOYO_RS18660	COG3402	PFAM membrane-flanked domain
BTOYO_RS18665	COG3428	Bacterial PH domain
BTOYO_RS18700	COG3402	PFAM membrane-flanked domain
BTOYO_RS18705	COG3428	Bacterial PH domain
BTOYO_RS18710	COG2329	Antibiotic biosynthesis monooxygenase
BTOYO_RS18715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTOYO_RS18730	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BTOYO_RS18755	COG1309	transcriptional regulator
BTOYO_RS18760	COG1511	domain protein
BTOYO_RS18795	COG1609	Transcriptional regulator
BTOYO_RS18805	COG1234	tRNA 3'-trailer cleavage
BTOYO_RS18810	COG0095	Lipoate-protein ligase
BTOYO_RS18820	COG0318	PFAM AMP-dependent synthetase and ligase
BTOYO_RS18840	COG1408	metallophosphoesterase
BTOYO_RS18850	COG1078	dGTPase activity
BTOYO_RS18860	COG1595	DNA-templated transcription, initiation
BTOYO_RS18865	COG3708	Transcriptional regulator
BTOYO_RS18865	COG2207	Transcriptional regulator
BTOYO_RS18875	COG2205	protein histidine kinase activity
BTOYO_RS18880	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS18905	COG0501	Belongs to the peptidase M48B family
BTOYO_RS18910	COG0840	transmembrane signaling receptor activity
BTOYO_RS18915	COG0697	spore germination
BTOYO_RS18920	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BTOYO_RS18925	COG2224	Isocitrate lyase
BTOYO_RS18955	COG4903	ComK protein
BTOYO_RS18960	COG0398	Pfam SNARE associated Golgi protein
BTOYO_RS19045	COG0367	asparagine synthase
BTOYO_RS19055	COG0753	catalase activity
BTOYO_RS19060	COG0004	ammonium transporteR
BTOYO_RS19080	COG2996	Protein conserved in bacteria
BTOYO_RS19100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTOYO_RS19115	COG0561	phosphatase activity
BTOYO_RS19135	COG2267	carboxylic ester hydrolase activity
BTOYO_RS19150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTOYO_RS19155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTOYO_RS19160	COG5504	Zn-dependent protease
BTOYO_RS19175	COG0180	Tryptophanyl-tRNA synthetase
BTOYO_RS19185	COG4166	transmembrane transport
BTOYO_RS19190	COG0601	transmembrane transport
BTOYO_RS19195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTOYO_RS19200	COG0444	Belongs to the ABC transporter superfamily
BTOYO_RS19205	COG4608	Belongs to the ABC transporter superfamily
BTOYO_RS19210	COG0534	Mate efflux family protein
BTOYO_RS19215	COG4166	transmembrane transport
BTOYO_RS19230	COG0861	Integral membrane protein TerC family
BTOYO_RS19240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTOYO_RS19250	COG1164	Oligoendopeptidase f
BTOYO_RS19260	COG2346	COG2346, Truncated hemoglobins
BTOYO_RS19265	COG4116	CYTH
BTOYO_RS19275	COG2357	RelA SpoT domain protein
BTOYO_RS19285	COG0564	pseudouridine synthase activity
BTOYO_RS19300	COG0772	Belongs to the SEDS family
BTOYO_RS19305	COG1216	Glycosyl transferase, family 2
BTOYO_RS19325	COG0463	Glycosyl transferase, family 2
BTOYO_RS19325	COG0457	Tetratricopeptide repeat
BTOYO_RS19345	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BTOYO_RS19360	COG1091	dTDP-4-dehydrorhamnose reductase activity
BTOYO_RS19405	COG2153	protein acetylation
BTOYO_RS19415	COG2382	esterase
BTOYO_RS19420	COG0697	spore germination
BTOYO_RS19430	COG5492	domain, Protein
BTOYO_RS19435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTOYO_RS19445	COG0512	Glutamine amidotransferase of anthranilate synthase
BTOYO_RS19445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTOYO_RS19450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTOYO_RS19465	COG0133	tryptophan synthase activity
BTOYO_RS19480	COG1620	l-lactate permease
BTOYO_RS19485	COG5634	Uncharacterized conserved protein (DUF2278)
BTOYO_RS19550	COG2226	methyltransferase
BTOYO_RS19570	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTOYO_RS19580	COG1476	TRANSCRIPTIONal
BTOYO_RS19615	COG4152	abc transporter atp-binding protein
BTOYO_RS19620	COG1668	transmembrane transport
BTOYO_RS19660	COG1686	Belongs to the peptidase S11 family
BTOYO_RS19665	COG0681	Belongs to the peptidase S26 family
BTOYO_RS19700	COG1012	belongs to the aldehyde dehydrogenase family
BTOYO_RS19710	COG1176	ABC-type spermidine putrescine transport system, permease component I
BTOYO_RS19715	COG1177	transmembrane transport
BTOYO_RS19720	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BTOYO_RS19730	COG2409	Drug exporters of the RND superfamily
BTOYO_RS19740	COG0564	pseudouridine synthase activity
BTOYO_RS19750	COG2340	Cysteine-rich secretory protein family
BTOYO_RS19755	COG0247	lactate metabolic process
BTOYO_RS19760	COG0277	FAD linked oxidase domain protein
BTOYO_RS19765	COG3835	regulator
BTOYO_RS19775	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS19780	COG5002	protein histidine kinase activity
BTOYO_RS19785	COG2186	Transcriptional regulator
BTOYO_RS19805	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BTOYO_RS19815	COG2116	formate transmembrane transporter activity
BTOYO_RS19820	COG0861	Integral membrane protein TerC family
BTOYO_RS19825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTOYO_RS19835	COG2030	dehydratase
BTOYO_RS19855	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS19860	COG3243	poly(R)-hydroxyalkanoic acid synthase
BTOYO_RS19870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTOYO_RS19885	COG1840	ABC-type Fe3 transport system, periplasmic component
BTOYO_RS19890	COG3842	ATPase activity
BTOYO_RS19915	COG1349	DNA-binding transcription factor activity
BTOYO_RS19930	COG0235	Class ii aldolase
BTOYO_RS19940	COG2861	carbohydrate metabolic process
BTOYO_RS19950	COG3852	Histidine kinase
BTOYO_RS19955	COG1846	Transcriptional regulator
BTOYO_RS19965	COG2318	DinB family
BTOYO_RS19975	COG5002	protein histidine kinase activity
BTOYO_RS19985	COG0720	synthase
BTOYO_RS20000	COG4873	Protein conserved in bacteria
BTOYO_RS20015	COG0456	acetyltransferase
BTOYO_RS20030	COG1780	Probably involved in ribonucleotide reductase function
BTOYO_RS20035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTOYO_RS20040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTOYO_RS20045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTOYO_RS20050	COG0531	amino acid
BTOYO_RS20055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTOYO_RS20070	COG2204	response regulator
BTOYO_RS20075	COG1012	belongs to the aldehyde dehydrogenase family
BTOYO_RS20085	COG1725	Transcriptional regulator
BTOYO_RS20090	COG1131	(ABC) transporter
BTOYO_RS20100	COG1131	(ABC) transporter
BTOYO_RS20105	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BTOYO_RS20110	COG1266	CAAX protease self-immunity
BTOYO_RS20120	COG1522	sequence-specific DNA binding
BTOYO_RS20130	COG1335	isochorismatase
BTOYO_RS20140	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTOYO_RS20145	COG2070	2-Nitropropane dioxygenase
BTOYO_RS20150	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BTOYO_RS20160	COG1696	Membrane protein involved in D-alanine export
BTOYO_RS20185	COG0716	FMN binding
BTOYO_RS20220	COG0534	Mate efflux family protein
BTOYO_RS20245	COG1846	Transcriptional regulator
BTOYO_RS20255	COG1301	dicarboxylic acid transport
BTOYO_RS20260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTOYO_RS20265	COG4709	membrane
BTOYO_RS20270	COG3874	Sporulation protein YtfJ
BTOYO_RS20290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTOYO_RS20295	COG0028	Belongs to the TPP enzyme family
BTOYO_RS20300	COG0440	acetolactate synthase activity
BTOYO_RS20320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BTOYO_RS20350	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BTOYO_RS20360	COG0107	imidazoleglycerol-phosphate synthase activity
BTOYO_RS20370	COG0140	phosphoribosyl-ATP diphosphatase activity
BTOYO_RS20375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTOYO_RS20385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTOYO_RS20390	COG1183	phosphatidylcholine synthase activity
BTOYO_RS20395	COG1368	sulfuric ester hydrolase activity
BTOYO_RS20405	COG0019	diaminopimelate decarboxylase activity
BTOYO_RS20425	COG0529	Catalyzes the synthesis of activated sulfate
BTOYO_RS20430	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTOYO_RS20450	COG1648	precorrin-2 dehydrogenase activity
BTOYO_RS20455	COG0733	neurotransmitter:sodium symporter activity
BTOYO_RS20475	COG1757	Na H antiporter
BTOYO_RS20490	COG4758	membrane
BTOYO_RS20495	COG4585	Histidine kinase
BTOYO_RS20500	COG2197	response regulator
BTOYO_RS20510	COG1114	Component of the transport system for branched-chain amino acids
BTOYO_RS20520	COG2226	methyltransferase
BTOYO_RS20560	COG0730	response to heat
BTOYO_RS20565	COG0306	phosphate transporter
BTOYO_RS20570	COG1392	Phosphate transport regulator
BTOYO_RS20575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTOYO_RS20590	COG3852	Histidine kinase
BTOYO_RS20595	COG1801	Protein of unknown function DUF72
BTOYO_RS20605	COG0582	viral genome integration into host DNA
BTOYO_RS20610	COG5002	protein histidine kinase activity
BTOYO_RS20625	COG0392	lysyltransferase activity
BTOYO_RS20625	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BTOYO_RS20640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTOYO_RS20645	COG1686	Belongs to the peptidase S11 family
BTOYO_RS20650	COG2715	membrane protein required for spore maturation
BTOYO_RS20655	COG0700	Nucleoside recognition
BTOYO_RS20660	COG1187	pseudouridine synthase activity
BTOYO_RS20670	COG1333	cytochrome c biogenesis protein
BTOYO_RS20675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTOYO_RS20680	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS20685	COG5002	protein histidine kinase activity
BTOYO_RS20690	COG2096	Adenosyltransferase
BTOYO_RS20695	COG4942	peptidase
BTOYO_RS20705	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BTOYO_RS20710	COG1141	Ferredoxin
BTOYO_RS20715	COG4955	Helix-turn-helix domain
BTOYO_RS20720	COG0514	ATP-dependent DNA helicase (RecQ)
BTOYO_RS20725	COG1266	CAAX protease self-immunity
BTOYO_RS20735	COG1408	metallophosphoesterase
BTOYO_RS20740	COG0789	Transcriptional regulator
BTOYO_RS20745	COG4862	establishment of competence for transformation
BTOYO_RS20750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTOYO_RS20770	COG0492	ferredoxin-NADP+ reductase activity
BTOYO_RS20775	COG0252	asparaginase activity
BTOYO_RS20840	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTOYO_RS20855	COG0142	geranyltranstransferase activity
BTOYO_RS20865	COG0142	geranyltranstransferase activity
BTOYO_RS20890	COG0457	Tetratricopeptide repeat
BTOYO_RS20910	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTOYO_RS20915	COG2010	Cytochrome c
BTOYO_RS20915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTOYO_RS20920	COG4347	Protein of unknown function (DUF1405)
BTOYO_RS20935	COG2738	Putative neutral zinc metallopeptidase
BTOYO_RS20945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTOYO_RS20950	COG1694	Mazg nucleotide pyrophosphohydrolase
BTOYO_RS20965	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BTOYO_RS20970	COG0438	transferase activity, transferring glycosyl groups
BTOYO_RS21010	COG1199	ATP-dependent helicase activity
BTOYO_RS21010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BTOYO_RS21030	COG3935	DnaD domain protein
BTOYO_RS21035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTOYO_RS21045	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTOYO_RS21045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTOYO_RS21090	COG3599	regulation of cell shape
BTOYO_RS21095	COG0116	Belongs to the methyltransferase superfamily
BTOYO_RS21105	COG1199	ATP-dependent helicase activity
BTOYO_RS21110	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BTOYO_RS21120	COG3173	Aminoglycoside phosphotransferase
BTOYO_RS21125	COG0024	Methionine aminopeptidase
BTOYO_RS21135	COG2233	PERMEase
BTOYO_RS21140	COG2311	Membrane
BTOYO_RS21145	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTOYO_RS21155	COG0456	acetyltransferase
BTOYO_RS21185	COG0754	glutathionylspermidine amidase activity
BTOYO_RS21200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTOYO_RS21215	COG0454	-acetyltransferase
BTOYO_RS21235	COG0328	RNA-DNA hybrid ribonuclease activity
BTOYO_RS21270	COG3403	YqcI/YcgG family
BTOYO_RS21275	COG1280	lysine exporter protein (LysE YggA)
BTOYO_RS21290	COG3162	membrane
BTOYO_RS21295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTOYO_RS21300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTOYO_RS21310	COG0475	glutathione-regulated potassium exporter activity
BTOYO_RS21315	COG0789	Transcriptional regulator
BTOYO_RS21315	COG4978	Transcriptional regulator
BTOYO_RS21325	COG2323	membrane
BTOYO_RS21330	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BTOYO_RS21360	COG2814	Major facilitator Superfamily
BTOYO_RS21380	COG1923	regulation of RNA biosynthetic process
BTOYO_RS21390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BTOYO_RS21395	COG1360	Flagellar Motor Protein
BTOYO_RS21400	COG2201	protein-glutamate methylesterase activity
BTOYO_RS21405	COG0643	Histidine kinase
BTOYO_RS21405	COG2198	Histidine kinase
BTOYO_RS21410	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTOYO_RS21410	COG1776	CheC inhibitor of MCP methylation
BTOYO_RS21425	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTOYO_RS21445	COG1256	bacterial-type flagellum assembly
BTOYO_RS21450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTOYO_RS21455	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BTOYO_RS21470	COG1815	bacterial-type flagellum-dependent cell motility
BTOYO_RS21475	COG1558	bacterial-type flagellum-dependent cell motility
BTOYO_RS21485	COG1766	The M ring may be actively involved in energy transduction
BTOYO_RS21490	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTOYO_RS21500	COG1157	protein secretion by the type III secretion system
BTOYO_RS21520	COG1749	Flagellar hook protein flgE
BTOYO_RS21535	COG0835	chemotaxis
BTOYO_RS21535	COG0784	Response regulator, receiver
BTOYO_RS21545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTOYO_RS21550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTOYO_RS21555	COG0741	lytic transglycosylase activity
BTOYO_RS21565	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTOYO_RS21570	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTOYO_RS21570	COG1776	CheC inhibitor of MCP methylation
BTOYO_RS21580	COG1338	Plays a role in the flagellum-specific transport system
BTOYO_RS21585	COG1987	bacterial-type flagellum assembly
BTOYO_RS21595	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTOYO_RS21600	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTOYO_RS21605	COG1419	protein localization to endoplasmic reticulum
BTOYO_RS21610	COG4787	bacterial-type flagellum-dependent cell motility
BTOYO_RS21650	COG2329	Antibiotic biosynthesis monooxygenase
BTOYO_RS21665	COG2814	Major facilitator Superfamily
BTOYO_RS21675	COG0583	DNA-binding transcription factor activity
BTOYO_RS21680	COG3842	ATPase activity
BTOYO_RS21685	COG1840	ABC-type Fe3 transport system, periplasmic component
BTOYO_RS21695	COG1234	tRNA 3'-trailer cleavage
BTOYO_RS21725	COG0406	alpha-ribazole phosphatase activity
BTOYO_RS21745	COG1846	Transcriptional regulator
BTOYO_RS21755	COG0367	asparagine synthase
BTOYO_RS21785	COG1802	Transcriptional regulator
BTOYO_RS21790	COG0697	spore germination
BTOYO_RS21800	COG0523	cobalamin synthesis protein
BTOYO_RS21805	COG0438	transferase activity, transferring glycosyl groups
BTOYO_RS21805	COG1216	Glycosyl transferase, family 2
BTOYO_RS21810	COG1757	Na H antiporter
BTOYO_RS21815	COG0789	Transcriptional regulator
BTOYO_RS21820	COG4221	oxidoreductase activity
BTOYO_RS21840	COG0534	Mate efflux family protein
BTOYO_RS21845	COG3340	Belongs to the peptidase S51 family
BTOYO_RS21865	COG0785	Cytochrome C biogenesis protein
BTOYO_RS21870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTOYO_RS21890	COG2733	membrane
BTOYO_RS21925	COG1131	(ABC) transporter
BTOYO_RS21940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTOYO_RS21945	COG0528	UMP kinase activity
BTOYO_RS21955	COG1027	Aspartate ammonia-lyase
BTOYO_RS21960	COG0281	malic enzyme
BTOYO_RS21965	COG4191	Histidine kinase
BTOYO_RS21970	COG0784	Response regulator, receiver
BTOYO_RS21975	COG1846	Transcriptional regulator
BTOYO_RS21985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTOYO_RS22005	COG3620	sequence-specific DNA binding
BTOYO_RS22035	COG2814	Major facilitator Superfamily
BTOYO_RS22060	COG0477	Major facilitator Superfamily
BTOYO_RS22065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTOYO_RS22075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTOYO_RS22080	COG2223	nitrite transmembrane transporter activity
BTOYO_RS22085	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTOYO_RS22100	COG2244	polysaccharide biosynthetic process
BTOYO_RS22105	COG0733	neurotransmitter:sodium symporter activity
BTOYO_RS22115	COG5566	PFAM Mor transcription activator
BTOYO_RS22120	COG2323	membrane
BTOYO_RS22135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTOYO_RS22145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTOYO_RS22150	COG0028	Belongs to the TPP enzyme family
BTOYO_RS22170	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTOYO_RS22190	COG2814	Major facilitator Superfamily
BTOYO_RS22195	COG3384	dioxygenase
BTOYO_RS22205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTOYO_RS22225	COG4166	transmembrane transport
BTOYO_RS22235	COG0535	radical SAM domain protein
BTOYO_RS22240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTOYO_RS22260	COG1914	H( )-stimulated, divalent metal cation uptake system
BTOYO_RS22275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTOYO_RS22285	COG0531	amino acid
BTOYO_RS22310	COG1266	CAAX protease self-immunity
BTOYO_RS22315	COG1309	transcriptional regulator
BTOYO_RS22320	COG2390	Transcriptional regulator
BTOYO_RS22330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTOYO_RS22335	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BTOYO_RS22340	COG0295	cytidine deaminase activity
BTOYO_RS22370	COG0583	DNA-binding transcription factor activity
BTOYO_RS22385	COG0006	proline dipeptidase activity
BTOYO_RS22390	COG2132	Multicopper oxidase
BTOYO_RS22435	COG1760	l-serine dehydratase
BTOYO_RS22440	COG1760	l-serine dehydratase
BTOYO_RS22445	COG0814	amino acid
BTOYO_RS22450	COG2205	protein histidine kinase activity
BTOYO_RS22480	COG2239	Acts as a magnesium transporter
BTOYO_RS22490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTOYO_RS22510	COG1073	alpha beta
BTOYO_RS22535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTOYO_RS22545	COG0583	DNA-binding transcription factor activity
BTOYO_RS22565	COG1114	Component of the transport system for branched-chain amino acids
BTOYO_RS22575	COG2372	response to copper ion
BTOYO_RS22575	COG1276	copper resistance
BTOYO_RS22580	COG4549	nuclear export factor GLE1
BTOYO_RS22585	COG0697	spore germination
BTOYO_RS22590	COG0583	DNA-binding transcription factor activity
BTOYO_RS22595	COG1959	2 iron, 2 sulfur cluster binding
BTOYO_RS22600	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BTOYO_RS22605	COG0778	Nitroreductase
BTOYO_RS22620	COG0628	permease
BTOYO_RS22635	COG1231	oxidoreductase activity
BTOYO_RS22640	COG0523	cobalamin synthesis protein
BTOYO_RS22650	COG0411	ABC transporter
BTOYO_RS22660	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTOYO_RS22670	COG0583	DNA-binding transcription factor activity
BTOYO_RS22695	COG1271	oxidase subunit
BTOYO_RS22700	COG1294	oxidase, subunit
BTOYO_RS22705	COG4988	ABC transporter
BTOYO_RS22710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BTOYO_RS22715	COG1216	Glycosyl transferase, family 2
BTOYO_RS22735	COG1686	Belongs to the peptidase S11 family
BTOYO_RS22750	COG0791	NLP P60 protein
BTOYO_RS22750	COG1388	LysM domain
BTOYO_RS22760	COG1132	(ABC) transporter
BTOYO_RS22765	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS22770	COG5002	protein histidine kinase activity
BTOYO_RS22775	COG0300	oxidoreductase activity
BTOYO_RS22780	COG4122	O-methyltransferase activity
BTOYO_RS22795	COG5658	integral membrane protein
BTOYO_RS22810	COG0460	homoserine dehydrogenase
BTOYO_RS22820	COG0083	homoserine kinase activity
BTOYO_RS22835	COG1316	TRANSCRIPTIONal
BTOYO_RS22845	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS22850	COG5002	protein histidine kinase activity
BTOYO_RS22865	COG1285	pathogenesis
BTOYO_RS22870	COG1247	-acetyltransferase
BTOYO_RS22890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTOYO_RS22900	COG1082	Xylose isomerase domain protein TIM barrel
BTOYO_RS22910	COG2814	Major facilitator Superfamily
BTOYO_RS22915	COG1279	arginine transmembrane transporter activity
BTOYO_RS22920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTOYO_RS22930	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTOYO_RS22965	COG0577	efflux transmembrane transporter activity
BTOYO_RS22970	COG2002	toxin-antitoxin pair type II binding
BTOYO_RS22975	COG1404	Belongs to the peptidase S8 family
BTOYO_RS22980	COG0640	Transcriptional regulator
BTOYO_RS22985	COG0667	Aldo Keto reductase
BTOYO_RS23025	COG3949	Membrane
BTOYO_RS23030	COG0783	Belongs to the Dps family
BTOYO_RS23045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTOYO_RS23055	COG1231	oxidoreductase activity
BTOYO_RS23060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTOYO_RS23065	COG4989	oxidoreductase activity
BTOYO_RS23070	COG0523	cobalamin synthesis protein
BTOYO_RS23080	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTOYO_RS23085	COG0702	epimerase
BTOYO_RS23095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTOYO_RS23105	COG4166	transmembrane transport
BTOYO_RS23110	COG0346	lactoylglutathione lyase activity
BTOYO_RS23120	COG0406	alpha-ribazole phosphatase activity
BTOYO_RS23130	COG5337	Spore coat protein CotH
BTOYO_RS23135	COG1051	belongs to the nudix hydrolase family
BTOYO_RS23140	COG0586	Pfam SNARE associated Golgi protein
BTOYO_RS23145	COG2244	polysaccharide biosynthetic process
BTOYO_RS23155	COG0701	Predicted permease
BTOYO_RS23160	COG3689	TIGRFAM TIGR03943 family protein
BTOYO_RS23165	COG1607	acyl-coa hydrolase
BTOYO_RS23170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTOYO_RS23185	COG0702	epimerase
BTOYO_RS23190	COG2839	Protein conserved in bacteria
BTOYO_RS23195	COG1253	flavin adenine dinucleotide binding
BTOYO_RS23210	COG1114	Component of the transport system for branched-chain amino acids
BTOYO_RS23215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTOYO_RS23230	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTOYO_RS23240	COG1876	peptidase activity
BTOYO_RS23250	COG0154	amidase activity
BTOYO_RS23255	COG2211	Major facilitator Superfamily
BTOYO_RS23270	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTOYO_RS23280	COG0561	phosphatase activity
BTOYO_RS23285	COG1846	Transcriptional regulator
BTOYO_RS23290	COG2814	Major facilitator Superfamily
BTOYO_RS23300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTOYO_RS23315	COG1819	glycosyl
BTOYO_RS23320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTOYO_RS23325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTOYO_RS23355	COG0456	acetyltransferase
BTOYO_RS23390	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTOYO_RS23510	COG4974	Belongs to the 'phage' integrase family
BTOYO_RS23520	COG3874	Sporulation protein YtfJ
BTOYO_RS23545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTOYO_RS23565	COG0346	lactoylglutathione lyase activity
BTOYO_RS23580	COG1595	DNA-templated transcription, initiation
BTOYO_RS23600	COG0426	domain, Protein
BTOYO_RS23600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTOYO_RS23610	COG0386	Belongs to the glutathione peroxidase family
BTOYO_RS23615	COG1305	Transglutaminase-like
BTOYO_RS23620	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BTOYO_RS23625	COG0714	Associated with various cellular activities
BTOYO_RS23630	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BTOYO_RS23635	COG1140	nitrate reductase beta subunit
BTOYO_RS23640	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BTOYO_RS23645	COG2181	nitrate reductase activity
BTOYO_RS23650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTOYO_RS23655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTOYO_RS23660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTOYO_RS23665	COG0303	'Molybdopterin
BTOYO_RS23670	COG0314	molybdopterin synthase activity
BTOYO_RS23680	COG2223	nitrite transmembrane transporter activity
BTOYO_RS23690	COG1648	precorrin-2 dehydrogenase activity
BTOYO_RS23700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BTOYO_RS23700	COG1587	Uroporphyrinogen-III synthase
BTOYO_RS23705	COG2146	nitrite reductase [NAD(P)H] activity
BTOYO_RS23710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTOYO_RS23715	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BTOYO_RS23745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTOYO_RS23785	COG2359	stage V sporulation protein S
BTOYO_RS23795	COG2856	Zn peptidase
BTOYO_RS23800	COG1396	sequence-specific DNA binding
BTOYO_RS23855	COG0662	Cupin 2, conserved barrel domain protein
BTOYO_RS23895	COG0582	viral genome integration into host DNA
BTOYO_RS23925	COG5484	DNA packaging
BTOYO_RS23930	COG1783	phage Terminase large subunit
BTOYO_RS23945	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BTOYO_RS23950	COG4653	Phage capsid family
BTOYO_RS24070	COG2132	Multicopper oxidase
BTOYO_RS24080	COG1418	mRNA catabolic process
BTOYO_RS24085	COG0488	(ABC) transporter
BTOYO_RS24100	COG0629	single-stranded DNA binding
BTOYO_RS24115	COG1413	lyase activity
BTOYO_RS24130	COG2521	methyltransferase
BTOYO_RS24130	COG2136	Putative SAM-dependent methyltransferase
BTOYO_RS24135	COG0018	arginyl-trna synthetase
BTOYO_RS24165	COG0017	Asparaginyl-tRNA synthetase
BTOYO_RS24170	COG0733	neurotransmitter:sodium symporter activity
BTOYO_RS24175	COG2267	carboxylic ester hydrolase activity
BTOYO_RS24195	COG2610	gluconate transmembrane transporter activity
BTOYO_RS24205	COG1794	racemase activity, acting on amino acids and derivatives
BTOYO_RS24215	COG0456	acetyltransferase
BTOYO_RS24220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTOYO_RS24235	COG0546	phosphoglycolate phosphatase activity
BTOYO_RS24250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTOYO_RS24265	COG0768	penicillin binding
BTOYO_RS24275	COG0204	Acyl-transferase
BTOYO_RS24280	COG1272	protein, Hemolysin III
BTOYO_RS24290	COG0805	protein transport
BTOYO_RS24300	COG1307	EDD domain protein, DegV family
BTOYO_RS24305	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BTOYO_RS24310	COG1999	signal sequence binding
BTOYO_RS24315	COG0071	Belongs to the small heat shock protein (HSP20) family
BTOYO_RS24320	COG0367	asparagine synthase
BTOYO_RS24335	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTOYO_RS24340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTOYO_RS24345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTOYO_RS24360	COG1335	isochorismatase
BTOYO_RS24365	COG1051	belongs to the nudix hydrolase family
BTOYO_RS24370	COG0668	transmembrane transport
BTOYO_RS24375	COG2203	Gaf domain
BTOYO_RS24375	COG4585	Histidine kinase
BTOYO_RS24380	COG2197	response regulator
BTOYO_RS24385	COG1737	Transcriptional regulator
BTOYO_RS24390	COG1064	alcohol dehydrogenase
BTOYO_RS24415	COG2801	Transposase and inactivated derivatives
BTOYO_RS24430	COG1070	Carbohydrate kinase
BTOYO_RS24440	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BTOYO_RS24475	COG0517	IMP dehydrogenase activity
BTOYO_RS24475	COG1125	glycine betaine transport
BTOYO_RS24480	COG1174	glycine betaine transport
BTOYO_RS24515	COG1253	flavin adenine dinucleotide binding
BTOYO_RS24520	COG1012	belongs to the aldehyde dehydrogenase family
BTOYO_RS24525	COG5506	Protein of unknown function (DUF1694)
BTOYO_RS24530	COG3852	Histidine kinase
BTOYO_RS24540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTOYO_RS24545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BTOYO_RS24550	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BTOYO_RS24555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTOYO_RS24560	COG0456	acetyltransferase
BTOYO_RS24565	COG3829	transcription factor binding
BTOYO_RS24570	COG1509	lysine 2,3-aminomutase activity
BTOYO_RS24600	COG4991	sh3 domain protein
BTOYO_RS24600	COG3064	Membrane
BTOYO_RS24600	COG0515	serine threonine protein kinase
BTOYO_RS24610	COG0671	phosphoesterase, PA-phosphatase related
BTOYO_RS24615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTOYO_RS24620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTOYO_RS24670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTOYO_RS24700	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS24720	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTOYO_RS24720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTOYO_RS24730	COG2814	Major facilitator Superfamily
BTOYO_RS24735	COG0372	Belongs to the citrate synthase family
BTOYO_RS24740	COG2079	MmgE PrpD family protein
BTOYO_RS24745	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BTOYO_RS24750	COG1960	acyl-CoA dehydrogenase activity
BTOYO_RS24755	COG2084	Dehydrogenase
BTOYO_RS24765	COG1280	lysine exporter protein (LysE YggA)
BTOYO_RS24770	COG1024	Enoyl-CoA hydratase
BTOYO_RS24785	COG0420	3'-5' exonuclease activity
BTOYO_RS24815	COG2223	nitrite transmembrane transporter activity
BTOYO_RS24820	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS24825	COG1169	isochorismate synthase
BTOYO_RS24830	COG1021	2,3-dihydroxybenzoate-AMP ligase
BTOYO_RS24835	COG1535	isochorismatase
BTOYO_RS24835	COG3433	isochorismatase activity
BTOYO_RS24840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BTOYO_RS24845	COG3251	PFAM MbtH domain protein
BTOYO_RS24850	COG2814	Major facilitator Superfamily
BTOYO_RS24865	COG0776	regulation of translation
BTOYO_RS24875	COG2318	DinB family
BTOYO_RS24895	COG1115	amino acid carrier protein
BTOYO_RS24905	COG2329	Antibiotic biosynthesis monooxygenase
BTOYO_RS24910	COG1187	pseudouridine synthase activity
BTOYO_RS24915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTOYO_RS24920	COG1136	(ABC) transporter
BTOYO_RS24945	COG0028	Belongs to the TPP enzyme family
BTOYO_RS24980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTOYO_RS24990	COG2207	Transcriptional regulator
BTOYO_RS25015	COG2755	lipolytic protein G-D-S-L family
BTOYO_RS25015	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BTOYO_RS25025	COG5002	protein histidine kinase activity
BTOYO_RS25035	COG0745	RESPONSE REGULATOR receiver
BTOYO_RS25055	COG1846	Transcriptional regulator
BTOYO_RS25070	COG1309	transcriptional regulator
BTOYO_RS25095	COG1247	-acetyltransferase
BTOYO_RS25110	COG1846	Transcriptional regulator
BTOYO_RS25130	COG1278	Cold shock
BTOYO_RS25145	COG1329	Transcriptional regulator
BTOYO_RS25180	COG2732	(Barnase) inhibitor
BTOYO_RS25190	COG0582	viral genome integration into host DNA
BTOYO_RS25210	COG1668	transmembrane transport
BTOYO_RS25215	COG4152	abc transporter atp-binding protein
BTOYO_RS25220	COG1028	Short-chain dehydrogenase reductase Sdr
BTOYO_RS25225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTOYO_RS25250	COG2801	Transposase and inactivated derivatives
BTOYO_RS25440	COG0561	phosphatase activity
BTOYO_RS25490	COG1923	regulation of RNA biosynthetic process
BTOYO_RS25535	COG3209	COG3209 Rhs family protein
BTOYO_RS25550	COG0582	viral genome integration into host DNA
BTOYO_RS25605	COG1674	ftsk spoiiie
BTOYO_RS25620	COG2376	Dihydroxyacetone kinase
