locus-tag	class	description
EXW33_RS00020	COG2868	ribosomal protein
EXW33_RS00175	COG0741	lytic transglycosylase activity
EXW33_RS00175	COG0791	NLP P60 protein
EXW33_RS00260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW33_RS00260	COG0551	DNA topoisomerase type I activity
EXW33_RS00290	COG4974	Belongs to the 'phage' integrase family
EXW33_RS00305	COG3593	DNA synthesis involved in DNA repair
EXW33_RS00310	COG0210	DNA helicase
EXW33_RS00355	COG0840	transmembrane signaling receptor activity
EXW33_RS00375	COG0789	Transcriptional regulator
EXW33_RS00385	COG2318	DinB family
EXW33_RS00390	COG2378	regulation of single-species biofilm formation
EXW33_RS00405	COG0582	viral genome integration into host DNA
EXW33_RS00415	COG4974	Belongs to the 'phage' integrase family
EXW33_RS00425	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW33_RS00470	COG1533	DNA photolyase activity
EXW33_RS00490	COG1090	epimerase
EXW33_RS00505	COG2155	Conserved Protein
EXW33_RS00515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW33_RS00525	COG0415	Belongs to the DNA photolyase family
EXW33_RS00535	COG2814	Major facilitator Superfamily
EXW33_RS00545	COG0288	reversible hydration of carbon dioxide
EXW33_RS00550	COG0640	Transcriptional regulator
EXW33_RS00625	COG1329	Transcriptional regulator
EXW33_RS00635	COG0662	Cupin 2, conserved barrel domain protein
EXW33_RS00685	COG0737	Belongs to the 5'-nucleotidase family
EXW33_RS00690	COG2267	carboxylic ester hydrolase activity
EXW33_RS00695	COG1335	isochorismatase
EXW33_RS00715	COG0583	DNA-binding transcription factor activity
EXW33_RS00725	COG0598	Magnesium transport protein CorA
EXW33_RS00760	COG0415	Belongs to the DNA photolyase family
EXW33_RS00765	COG0288	reversible hydration of carbon dioxide
EXW33_RS00775	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW33_RS00780	COG5609	conserved protein (DUF2294)
EXW33_RS00785	COG2814	Major facilitator Superfamily
EXW33_RS00790	COG0583	DNA-binding transcription factor activity
EXW33_RS00815	COG5002	protein histidine kinase activity
EXW33_RS00820	COG0745	RESPONSE REGULATOR receiver
EXW33_RS00825	COG0456	acetyltransferase
EXW33_RS00830	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW33_RS00835	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW33_RS00840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW33_RS00845	COG1121	(ABC) transporter
EXW33_RS00860	COG1999	signal sequence binding
EXW33_RS00865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW33_RS00870	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW33_RS00890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW33_RS00900	COG0798	PFAM Bile acid sodium symporter
EXW33_RS00905	COG0346	lactoylglutathione lyase activity
EXW33_RS00910	COG0640	Transcriptional regulator
EXW33_RS00920	COG0825	malonyl-CoA metabolic process
EXW33_RS00930	COG3320	Male sterility
EXW33_RS00930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW33_RS00935	COG1309	transcriptional regulator
EXW33_RS00940	COG2186	Transcriptional regulator
EXW33_RS00955	COG0814	amino acid
EXW33_RS00960	COG0697	spore germination
EXW33_RS00975	COG1522	sequence-specific DNA binding
EXW33_RS00990	COG0346	lactoylglutathione lyase activity
EXW33_RS01050	COG0384	phenazine biosynthesis protein PhzF
EXW33_RS01055	COG2814	Major facilitator Superfamily
EXW33_RS01060	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW33_RS01075	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW33_RS01095	COG0577	efflux transmembrane transporter activity
EXW33_RS01115	COG5002	protein histidine kinase activity
EXW33_RS01115	COG3850	Histidine kinase
EXW33_RS01125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW33_RS01140	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW33_RS01160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW33_RS01210	COG2814	Major facilitator Superfamily
EXW33_RS01240	COG4282	regulation of fungal-type cell wall biogenesis
EXW33_RS01295	COG1876	peptidase activity
EXW33_RS01300	COG2843	Capsule synthesis protein
EXW33_RS01310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW33_RS01315	COG1012	belongs to the aldehyde dehydrogenase family
EXW33_RS01325	COG0534	Mate efflux family protein
EXW33_RS01330	COG1012	belongs to the aldehyde dehydrogenase family
EXW33_RS01335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW33_RS01350	COG0477	Major facilitator Superfamily
EXW33_RS01365	COG1846	Transcriptional regulator
EXW33_RS01370	COG2814	Major facilitator Superfamily
EXW33_RS01390	COG1819	glycosyl
EXW33_RS01395	COG2031	fatty acid transporter
EXW33_RS01405	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW33_RS01460	COG1288	antiporter activity
EXW33_RS01465	COG2356	endonuclease I
EXW33_RS01475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW33_RS01480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW33_RS01500	COG1733	regulation of RNA biosynthetic process
EXW33_RS01505	COG0778	Nitroreductase
EXW33_RS01535	COG1028	Short-chain dehydrogenase reductase Sdr
EXW33_RS01545	COG1131	(ABC) transporter
EXW33_RS01570	COG1011	Hydrolase
EXW33_RS01580	COG2365	Tyrosine phosphatase family
EXW33_RS01605	COG0346	lactoylglutathione lyase activity
EXW33_RS01610	COG1940	carbohydrate kinase activity
EXW33_RS01620	COG0110	maltose O-acetyltransferase activity
EXW33_RS01635	COG0628	permease
EXW33_RS01660	COG0477	Major facilitator Superfamily
EXW33_RS01680	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW33_RS01690	COG1253	flavin adenine dinucleotide binding
EXW33_RS01695	COG0789	Transcriptional regulator
EXW33_RS01705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW33_RS01730	COG0697	spore germination
EXW33_RS01740	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW33_RS01745	COG3813	Protein conserved in bacteria
EXW33_RS01750	COG2706	6-phosphogluconolactonase activity
EXW33_RS01755	COG1070	Carbohydrate kinase
EXW33_RS01770	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW33_RS01780	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW33_RS01785	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW33_RS01830	COG0814	amino acid
EXW33_RS01835	COG3655	Transcriptional regulator
EXW33_RS01865	COG1393	Belongs to the ArsC family
EXW33_RS01870	COG1733	regulation of RNA biosynthetic process
EXW33_RS01875	COG2188	Transcriptional regulator
EXW33_RS01880	COG0673	inositol 2-dehydrogenase activity
EXW33_RS01900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW33_RS01930	COG0318	PFAM AMP-dependent synthetase and ligase
EXW33_RS01935	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW33_RS01940	COG1733	regulation of RNA biosynthetic process
EXW33_RS01970	COG1191	sigma factor activity
EXW33_RS01980	COG1280	lysine exporter protein (LysE YggA)
EXW33_RS02025	COG1151	hydroxylamine reductase activity
EXW33_RS02035	COG3409	Peptidoglycan-binding domain 1 protein
EXW33_RS02035	COG3757	hydrolase, family 25
EXW33_RS02070	COG2072	flavoprotein involved in K transport
EXW33_RS02105	COG0604	alcohol dehydrogenase
EXW33_RS02110	COG1113	amino acid transport
EXW33_RS02120	COG2814	Major facilitator Superfamily
EXW33_RS02170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW33_RS02175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW33_RS02185	COG1247	-acetyltransferase
EXW33_RS02190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW33_RS02195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW33_RS02200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW33_RS02205	COG3739	integral membrane protein
EXW33_RS02235	COG0583	DNA-binding transcription factor activity
EXW33_RS02260	COG1193	negative regulation of DNA recombination
EXW33_RS02270	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW33_RS02275	COG1164	Oligoendopeptidase f
EXW33_RS02300	COG3781	membrane
EXW33_RS02315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW33_RS02330	COG0583	DNA-binding transcription factor activity
EXW33_RS02340	COG0584	glycerophosphoryl diester phosphodiesterase
EXW33_RS02350	COG0640	Transcriptional regulator
EXW33_RS02355	COG0604	alcohol dehydrogenase
EXW33_RS02365	COG0457	Tetratricopeptide repeat
EXW33_RS02380	COG2808	Putative FMN-binding domain
EXW33_RS02385	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW33_RS02400	COG0277	FAD linked oxidase domain protein
EXW33_RS02415	COG3858	chitin binding
EXW33_RS02425	COG5001	Diguanylate cyclase
EXW33_RS02425	COG3300	MHYT domain
EXW33_RS02435	COG1876	peptidase activity
EXW33_RS02465	COG3852	Histidine kinase
EXW33_RS02475	COG1285	pathogenesis
EXW33_RS02485	COG2514	catechol 2,3-dioxygenase activity
EXW33_RS02490	COG2720	vancomycin resistance protein
EXW33_RS02525	COG0716	FMN binding
EXW33_RS02555	COG1028	Short-chain dehydrogenase reductase Sdr
EXW33_RS02565	COG0165	Argininosuccinate lyase
EXW33_RS02580	COG4145	pantothenate transmembrane transporter activity
EXW33_RS02590	COG1012	belongs to the aldehyde dehydrogenase family
EXW33_RS02595	COG1028	Short-chain dehydrogenase reductase Sdr
EXW33_RS02605	COG1657	PFAM Prenyltransferase squalene oxidase
EXW33_RS02610	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW33_RS02615	COG2962	Rard protein
EXW33_RS02620	COG3326	Membrane
EXW33_RS02635	COG0489	protein tyrosine kinase activity
EXW33_RS02645	COG0314	molybdopterin synthase activity
EXW33_RS02650	COG0303	'Molybdopterin
EXW33_RS02655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW33_RS02660	COG2116	formate transmembrane transporter activity
EXW33_RS02670	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW33_RS02675	COG5609	conserved protein (DUF2294)
EXW33_RS02680	COG2427	Protein of unknown function (DUF1641)
EXW33_RS02685	COG3383	formate dehydrogenase (NAD+) activity
EXW33_RS02700	COG0531	amino acid
EXW33_RS02735	COG2226	methyltransferase
EXW33_RS02740	COG4166	transmembrane transport
EXW33_RS02745	COG4166	transmembrane transport
EXW33_RS02750	COG4166	transmembrane transport
EXW33_RS02760	COG1316	TRANSCRIPTIONal
EXW33_RS02770	COG1595	DNA-templated transcription, initiation
EXW33_RS02780	COG1131	(ABC) transporter
EXW33_RS02790	COG0673	inositol 2-dehydrogenase activity
EXW33_RS02795	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW33_RS02800	COG0187	DNA topoisomerase II activity
EXW33_RS02805	COG1832	CoA-binding protein
EXW33_RS02810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW33_RS02815	COG0745	RESPONSE REGULATOR receiver
EXW33_RS02835	COG4841	protein insertion into membrane
EXW33_RS02840	COG0824	Thioesterase
EXW33_RS02865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW33_RS02875	COG1132	(ABC) transporter
EXW33_RS02880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW33_RS02910	COG2211	Major facilitator Superfamily
EXW33_RS02920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW33_RS02935	COG0183	Belongs to the thiolase family
EXW33_RS02940	COG0318	PFAM AMP-dependent synthetase and ligase
EXW33_RS02945	COG1268	BioY protein
EXW33_RS02950	COG0318	PFAM AMP-dependent synthetase and ligase
EXW33_RS02955	COG1396	sequence-specific DNA binding
EXW33_RS02995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW33_RS03005	COG5002	protein histidine kinase activity
EXW33_RS03010	COG0400	carboxylic ester hydrolase activity
EXW33_RS03015	COG0346	lactoylglutathione lyase activity
EXW33_RS03020	COG0069	glutamate synthase activity
EXW33_RS03025	COG1902	pentaerythritol trinitrate reductase activity
EXW33_RS03030	COG1329	Transcriptional regulator
EXW33_RS03035	COG0010	Belongs to the arginase family
EXW33_RS03060	COG2226	methyltransferase
EXW33_RS03085	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW33_RS03090	COG0785	Cytochrome C biogenesis protein
EXW33_RS03100	COG1473	amidohydrolase
EXW33_RS03110	COG1131	(ABC) transporter
EXW33_RS03125	COG0583	DNA-binding transcription factor activity
EXW33_RS03135	COG1346	cytolysis
EXW33_RS03150	COG0730	response to heat
EXW33_RS03175	COG1132	(ABC) transporter
EXW33_RS03180	COG1132	(ABC) transporter
EXW33_RS03185	COG3763	UPF0154 protein
EXW33_RS03205	COG3639	organic phosphonate transmembrane transporter activity
EXW33_RS03220	COG0737	Belongs to the 5'-nucleotidase family
EXW33_RS03230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW33_RS03250	COG1695	Transcriptional regulator
EXW33_RS03255	COG1132	(ABC) transporter
EXW33_RS03285	COG0367	asparagine synthase
EXW33_RS03290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW33_RS03300	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW33_RS03305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW33_RS03310	COG3420	alginic acid biosynthetic process
EXW33_RS03310	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW33_RS03335	COG0438	transferase activity, transferring glycosyl groups
EXW33_RS03345	COG0463	Glycosyl transferase, family 2
EXW33_RS03345	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW33_RS03350	COG0438	transferase activity, transferring glycosyl groups
EXW33_RS03355	COG0438	transferase activity, transferring glycosyl groups
EXW33_RS03360	COG1086	Polysaccharide biosynthesis protein
EXW33_RS03365	COG0489	protein tyrosine kinase activity
EXW33_RS03385	COG0739	heme binding
EXW33_RS03385	COG0741	lytic transglycosylase activity
EXW33_RS03385	COG1196	nuclear chromosome segregation
EXW33_RS03390	COG0741	lytic transglycosylase activity
EXW33_RS03420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW33_RS03425	COG0174	glutamine synthetase
EXW33_RS03430	COG0789	Transcriptional regulator
EXW33_RS03435	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW33_RS03440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW33_RS03445	COG2860	membrane
EXW33_RS03455	COG0464	growth
EXW33_RS03485	COG1388	LysM domain
EXW33_RS03485	COG3584	3D domain protein
EXW33_RS03490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW33_RS03490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW33_RS03490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW33_RS03495	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW33_RS03500	COG1349	DNA-binding transcription factor activity
EXW33_RS03505	COG1979	alcohol dehydrogenase
EXW33_RS03510	COG2322	membrane
EXW33_RS03520	COG1113	amino acid transport
EXW33_RS03530	COG1473	amidohydrolase
EXW33_RS03535	COG1408	metallophosphoesterase
EXW33_RS03555	COG2217	Heavy metal translocating P-type atpase
EXW33_RS03560	COG2608	mercury ion transmembrane transporter activity
EXW33_RS03565	COG1937	Protein conserved in bacteria
EXW33_RS03585	COG2819	hydrolase of the alpha beta superfamily
EXW33_RS03590	COG1120	ATPase activity
EXW33_RS03595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW33_RS03600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW33_RS03605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW33_RS03610	COG0708	Exodeoxyribonuclease III
EXW33_RS03615	COG2169	Transcriptional regulator
EXW33_RS03620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW33_RS03625	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW33_RS03635	COG2364	Membrane
EXW33_RS03655	COG3300	MHYT domain
EXW33_RS03655	COG5001	Diguanylate cyclase
EXW33_RS03695	COG1346	cytolysis
EXW33_RS03705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW33_RS03710	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW33_RS03710	COG0596	Alpha beta hydrolase
EXW33_RS03715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW33_RS03735	COG1404	Belongs to the peptidase S8 family
EXW33_RS03740	COG3773	Cell wall hydrolase
EXW33_RS03750	COG1368	sulfuric ester hydrolase activity
EXW33_RS03765	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW33_RS03780	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW33_RS03790	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW33_RS03795	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW33_RS03795	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW33_RS03805	COG2359	stage V sporulation protein S
EXW33_RS03810	COG1692	metallophosphoesterase
EXW33_RS03840	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW33_RS03845	COG1426	Protein conserved in bacteria
EXW33_RS03860	COG0300	oxidoreductase activity
EXW33_RS03865	COG0612	Peptidase, M16
EXW33_RS03870	COG0612	Peptidase, M16
EXW33_RS03875	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW33_RS03880	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW33_RS03885	COG3845	ABC transporter
EXW33_RS03890	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW33_RS03895	COG2188	Transcriptional regulator
EXW33_RS03900	COG1674	ftsk spoiiie
EXW33_RS03910	COG0740	serine-type endopeptidase activity
EXW33_RS03915	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW33_RS03925	COG0527	aspartate kinase activity
EXW33_RS03930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW33_RS03935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW33_RS03940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW33_RS03945	COG1873	PFAM PRC-barrel domain
EXW33_RS03950	COG0612	Peptidase, M16
EXW33_RS03955	COG0726	polysaccharide deacetylase
EXW33_RS03970	COG0196	riboflavin kinase activity
EXW33_RS03980	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW33_RS03985	COG1550	Protein conserved in bacteria
EXW33_RS03995	COG1358	cellular component organization or biogenesis
EXW33_RS04000	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW33_RS04005	COG0195	Participates in both transcription termination and antitermination
EXW33_RS04025	COG0750	zinc metalloprotease
EXW33_RS04035	COG4589	Belongs to the CDS family
EXW33_RS04050	COG0528	UMP kinase activity
EXW33_RS04055	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW33_RS04080	COG4974	Belongs to the 'phage' integrase family
EXW33_RS04090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW33_RS04095	COG0758	DNA mediated transformation
EXW33_RS04100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW33_RS04125	COG0335	large ribosomal subunit rRNA binding
EXW33_RS04140	COG1837	Belongs to the UPF0109 family
EXW33_RS04150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW33_RS04160	COG0552	protein localization to endoplasmic reticulum
EXW33_RS04165	COG1196	nuclear chromosome segregation
EXW33_RS04175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW33_RS04180	COG1028	Short-chain dehydrogenase reductase Sdr
EXW33_RS04185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW33_RS04200	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW33_RS04205	COG1461	Dihydroxyacetone kinase
EXW33_RS04210	COG1302	Protein conserved in bacteria
EXW33_RS04225	COG1564	THIamine pyrophosphokinase
EXW33_RS04230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW33_RS04235	COG1162	GTPase activity
EXW33_RS04240	COG2815	serine threonine protein kinase
EXW33_RS04240	COG0515	serine threonine protein kinase
EXW33_RS04245	COG0631	protein serine/threonine phosphatase activity
EXW33_RS04255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW33_RS04255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW33_RS04260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW33_RS04270	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW33_RS04275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW33_RS04295	COG1561	YicC-like family, N-terminal region
EXW33_RS04300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW33_RS04310	COG0006	proline dipeptidase activity
EXW33_RS04440	COG0564	pseudouridine synthase activity
EXW33_RS04460	COG3599	regulation of cell shape
EXW33_RS04465	COG2302	S4 RNA-binding domain
EXW33_RS04470	COG0762	integral membrane protein
EXW33_RS04480	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW33_RS04490	COG1873	PFAM PRC-barrel domain
EXW33_RS04495	COG1191	sigma factor activity
EXW33_RS04500	COG1191	sigma factor activity
EXW33_RS04510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW33_RS04515	COG0849	cell division
EXW33_RS04520	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW33_RS04535	COG0772	Belongs to the SEDS family
EXW33_RS04555	COG0768	penicillin binding
EXW33_RS04560	COG0768	penicillin binding
EXW33_RS04580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW33_RS04595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW33_RS04600	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW33_RS04610	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW33_RS04615	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW33_RS04620	COG3314	Sporulation integral membrane protein YlbJ
EXW33_RS04630	COG0742	ribosomal rna small subunit methyltransferase
EXW33_RS04645	COG3679	Belongs to the UPF0342 family
EXW33_RS04650	COG0406	alpha-ribazole phosphatase activity
EXW33_RS04665	COG2340	Cysteine-rich secretory protein family
EXW33_RS04680	COG3336	cytochrome c oxidase
EXW33_RS04715	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW33_RS04720	COG0772	Belongs to the SEDS family
EXW33_RS04730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW33_RS04735	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW33_RS04745	COG4896	Protein conserved in bacteria
EXW33_RS04760	COG1217	gtp-binding protein TYPA
EXW33_RS04770	COG0483	inositol monophosphate 1-phosphatase activity
EXW33_RS04790	COG1982	Orn Lys Arg decarboxylase major
EXW33_RS04850	COG0022	dehydrogenase e1 component
EXW33_RS04855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW33_RS04870	COG0561	phosphatase activity
EXW33_RS04875	COG5503	Protein of unknown function (DUF1447)
EXW33_RS04880	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW33_RS04885	COG0569	domain protein
EXW33_RS04900	COG2171	N-acyltransferase activity
EXW33_RS04905	COG0583	DNA-binding transcription factor activity
EXW33_RS04910	COG0517	IMP dehydrogenase activity
EXW33_RS04920	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW33_RS04930	COG4703	Protein of unknown function (DUF1797)
EXW33_RS04950	COG2200	EAL domain
EXW33_RS04955	COG1028	Short-chain dehydrogenase reductase Sdr
EXW33_RS04960	COG1408	metallophosphoesterase
EXW33_RS04970	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EXW33_RS05005	COG2814	Major facilitator Superfamily
EXW33_RS05025	COG3209	COG3209 Rhs family protein
EXW33_RS05035	COG2205	protein histidine kinase activity
EXW33_RS05045	COG0436	Aminotransferase
EXW33_RS05050	COG1609	Transcriptional regulator
EXW33_RS05055	COG3833	ABC-type maltose transport systems, permease component
EXW33_RS05060	COG1175	transmembrane transport
EXW33_RS05065	COG2182	Extracellular solute-binding protein
EXW33_RS05075	COG0366	Alpha amylase catalytic
EXW33_RS05080	COG3842	ATPase activity
EXW33_RS05120	COG0183	Belongs to the thiolase family
EXW33_RS05155	COG1695	Transcriptional regulator
EXW33_RS05160	COG1028	Short-chain dehydrogenase reductase Sdr
EXW33_RS05175	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW33_RS05180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW33_RS05185	COG0436	Aminotransferase
EXW33_RS05220	COG2084	Dehydrogenase
EXW33_RS05230	COG2199	diguanylate cyclase activity
EXW33_RS05235	COG0778	Nitroreductase
EXW33_RS05260	COG1263	PTS System
EXW33_RS05260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW33_RS05260	COG2190	(PTS) system
EXW33_RS05265	COG3711	transcriptional antiterminator
EXW33_RS05275	COG2188	Transcriptional regulator
EXW33_RS05285	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW33_RS05310	COG1547	Domain of unknown function (DUF309)
EXW33_RS05315	COG0456	acetyltransferase
EXW33_RS05320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW33_RS05325	COG4086	secreted protein
EXW33_RS05330	COG0561	phosphatase activity
EXW33_RS05335	COG0697	spore germination
EXW33_RS05350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW33_RS05375	COG0733	neurotransmitter:sodium symporter activity
EXW33_RS05395	COG1686	Belongs to the peptidase S11 family
EXW33_RS05400	COG1725	Transcriptional regulator
EXW33_RS05405	COG1131	(ABC) transporter
EXW33_RS05425	COG1846	Transcriptional regulator
EXW33_RS05440	COG0598	Magnesium transport protein CorA
EXW33_RS05465	COG4974	Belongs to the 'phage' integrase family
EXW33_RS05475	COG0735	belongs to the Fur family
EXW33_RS05480	COG1300	Membrane
EXW33_RS05500	COG0667	Aldo Keto reductase
EXW33_RS05505	COG0656	L-ascorbic acid biosynthetic process
EXW33_RS05510	COG0456	acetyltransferase
EXW33_RS05510	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW33_RS05520	COG0737	Belongs to the 5'-nucleotidase family
EXW33_RS05520	COG1525	nuclease
EXW33_RS05520	COG4085	toxin activity
EXW33_RS05530	COG0596	Alpha beta hydrolase
EXW33_RS05535	COG2056	Na+-H+ antiporter family
EXW33_RS05540	COG1609	Transcriptional regulator
EXW33_RS05545	COG0454	-acetyltransferase
EXW33_RS05550	COG1073	alpha beta
EXW33_RS05565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW33_RS05565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW33_RS05570	COG0307	riboflavin synthase, alpha
EXW33_RS05595	COG4106	trans-aconitate 2-methyltransferase activity
EXW33_RS05600	COG1073	alpha beta
EXW33_RS05600	COG2226	methyltransferase
EXW33_RS05615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW33_RS05625	COG1757	Na H antiporter
EXW33_RS05630	COG0737	Belongs to the 5'-nucleotidase family
EXW33_RS05640	COG1522	sequence-specific DNA binding
EXW33_RS05675	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW33_RS05685	COG0300	oxidoreductase activity
EXW33_RS05690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW33_RS05695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW33_RS05700	COG1760	l-serine dehydratase
EXW33_RS05705	COG1760	l-serine dehydratase
EXW33_RS05730	COG1285	pathogenesis
EXW33_RS05745	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW33_RS05750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW33_RS05765	COG1376	ErfK ybiS ycfS ynhG family protein
EXW33_RS05770	COG4129	membrane
EXW33_RS05775	COG1126	abc transporter atp-binding protein
EXW33_RS05780	COG0765	amino acid transport
EXW33_RS05785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW33_RS05800	COG2816	NAD+ diphosphatase activity
EXW33_RS05805	COG2323	membrane
EXW33_RS05810	COG0772	Belongs to the SEDS family
EXW33_RS05815	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW33_RS05820	COG0022	dehydrogenase e1 component
EXW33_RS05825	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW33_RS05830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW33_RS05845	COG0280	phosphate acetyltransferase
EXW33_RS05850	COG3829	transcription factor binding
EXW33_RS05850	COG3290	protein histidine kinase activity
EXW33_RS05860	COG0584	glycerophosphoryl diester phosphodiesterase
EXW33_RS05865	COG3093	addiction module antidote protein HigA
EXW33_RS05870	COG1215	transferase activity, transferring glycosyl groups
EXW33_RS05880	COG0745	RESPONSE REGULATOR receiver
EXW33_RS05885	COG0750	zinc metalloprotease
EXW33_RS05890	COG0497	DNA recombination
EXW33_RS05900	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW33_RS05910	COG0142	geranyltranstransferase activity
EXW33_RS05930	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW33_RS05935	COG1302	Protein conserved in bacteria
EXW33_RS05940	COG0439	Biotin carboxylase
EXW33_RS05945	COG0511	ligase activity, forming carbon-carbon bonds
EXW33_RS05990	COG3854	ATPases associated with a variety of cellular activities
EXW33_RS06015	COG0006	proline dipeptidase activity
EXW33_RS06030	COG3872	metal-dependent enzyme
EXW33_RS06040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW33_RS06070	COG0095	Lipoate-protein ligase
EXW33_RS06075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW33_RS06085	COG1609	Transcriptional regulator
EXW33_RS06095	COG2076	Multidrug Resistance protein
EXW33_RS06100	COG2076	Multidrug Resistance protein
EXW33_RS06130	COG1131	(ABC) transporter
EXW33_RS06135	COG1725	Transcriptional regulator
EXW33_RS06150	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW33_RS06160	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW33_RS06165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW33_RS06220	COG4970	Tfp pilus assembly protein FimT
EXW33_RS06230	COG1459	type II secretion system
EXW33_RS06235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW33_RS06290	COG0646	methionine synthase
EXW33_RS06290	COG1410	methionine synthase
EXW33_RS06295	COG0646	methionine synthase
EXW33_RS06295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW33_RS06300	COG0626	cystathionine gamma-synthase activity
EXW33_RS06305	COG0626	cystathionine gamma-synthase activity
EXW33_RS06330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW33_RS06340	COG1940	carbohydrate kinase activity
EXW33_RS06345	COG4483	Protein conserved in bacteria
EXW33_RS06350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW33_RS06355	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW33_RS06360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW33_RS06365	COG0704	Plays a role in the regulation of phosphate uptake
EXW33_RS06375	COG0581	inorganic phosphate transmembrane transporter activity
EXW33_RS06380	COG0573	inorganic phosphate transmembrane transporter activity
EXW33_RS06385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW33_RS06390	COG0768	penicillin binding
EXW33_RS06395	COG0477	Major facilitator Superfamily
EXW33_RS06400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW33_RS06425	COG0735	belongs to the Fur family
EXW33_RS06430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW33_RS06435	COG1121	(ABC) transporter
EXW33_RS06440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW33_RS06470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW33_RS06475	COG2384	SAM-dependent methyltransferase
EXW33_RS06480	COG2010	Cytochrome c
EXW33_RS06485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW33_RS06490	COG0358	DNA primase activity
EXW33_RS06495	COG1671	Belongs to the UPF0178 family
EXW33_RS06505	COG0517	IMP dehydrogenase activity
EXW33_RS06520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW33_RS06525	COG0295	cytidine deaminase activity
EXW33_RS06530	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW33_RS06535	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW33_RS06540	COG1480	7TM receptor with intracellular HD hydrolase
EXW33_RS06545	COG1702	phosphate starvation-inducible protein PhoH
EXW33_RS06560	COG1610	YqeY-like protein
EXW33_RS06565	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW33_RS06570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW33_RS06575	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW33_RS06585	COG0484	heat shock protein binding
EXW33_RS06600	COG1420	regulation of RNA biosynthetic process
EXW33_RS06605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW33_RS06610	COG1733	regulation of RNA biosynthetic process
EXW33_RS06635	COG1466	dna polymerase III delta subunit
EXW33_RS06645	COG0658	competence protein
EXW33_RS06645	COG2333	competence protein COMEC
EXW33_RS06650	COG2131	deaminase
EXW33_RS06655	COG1555	photosystem II stabilization
EXW33_RS06655	COG1596	polysaccharide export
EXW33_RS06660	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW33_RS06665	COG2226	methyltransferase
EXW33_RS06670	COG0799	negative regulation of ribosome biogenesis
EXW33_RS06675	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW33_RS06680	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW33_RS06685	COG1534	Rna-binding protein
EXW33_RS06695	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW33_RS06700	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW33_RS06735	COG0778	Nitroreductase
EXW33_RS06740	COG2357	RelA SpoT domain protein
EXW33_RS06750	COG1785	Belongs to the alkaline phosphatase family
EXW33_RS06760	COG2267	carboxylic ester hydrolase activity
EXW33_RS06795	COG1404	Belongs to the peptidase S8 family
EXW33_RS06800	COG3186	Phenylalanine-4-hydroxylase
EXW33_RS06810	COG2514	catechol 2,3-dioxygenase activity
EXW33_RS06815	COG2259	Doxx family
EXW33_RS06855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW33_RS06865	COG1454	alcohol dehydrogenase
EXW33_RS06865	COG1012	belongs to the aldehyde dehydrogenase family
EXW33_RS06870	COG0626	cystathionine gamma-synthase activity
EXW33_RS06875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW33_RS06900	COG0768	penicillin binding
EXW33_RS06915	COG0826	peptidase U32
EXW33_RS06920	COG0826	peptidase U32
EXW33_RS06925	COG4122	O-methyltransferase activity
EXW33_RS06930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW33_RS06945	COG4472	Bacterial protein of unknown function (DUF965)
EXW33_RS06960	COG0628	permease
EXW33_RS06980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW33_RS06995	COG1104	cysteine desulfurase activity
EXW33_RS07000	COG1959	2 iron, 2 sulfur cluster binding
EXW33_RS07005	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW33_RS07015	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW33_RS07050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW33_RS07060	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW33_RS07060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW33_RS07065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW33_RS07070	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW33_RS07070	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW33_RS07080	COG2244	polysaccharide biosynthetic process
EXW33_RS07085	COG2323	membrane
EXW33_RS07095	COG1862	Preprotein translocase
EXW33_RS07100	COG0343	queuine tRNA-ribosyltransferase activity
EXW33_RS07115	COG2255	four-way junction helicase activity
EXW33_RS07120	COG0632	four-way junction helicase activity
EXW33_RS07125	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW33_RS07155	COG0157	Belongs to the NadC ModD family
EXW33_RS07160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW33_RS07165	COG1104	cysteine desulfurase activity
EXW33_RS07170	COG1827	regulation of RNA biosynthetic process
EXW33_RS07175	COG2258	MOSC domain
EXW33_RS07180	COG0077	Prephenate dehydratase
EXW33_RS07185	COG0577	efflux transmembrane transporter activity
EXW33_RS07190	COG0577	efflux transmembrane transporter activity
EXW33_RS07195	COG1136	(ABC) transporter
EXW33_RS07200	COG5002	protein histidine kinase activity
EXW33_RS07205	COG0745	RESPONSE REGULATOR receiver
EXW33_RS07220	COG3290	protein histidine kinase activity
EXW33_RS07230	COG2868	ribosomal protein
EXW33_RS07240	COG1530	ribonuclease E activity
EXW33_RS07245	COG1994	Peptidase M50
EXW33_RS07250	COG0739	heme binding
EXW33_RS07255	COG2894	cell division
EXW33_RS07275	COG1077	Cell shape determining protein MreB Mrl
EXW33_RS07310	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW33_RS07540	COG0285	dihydrofolate synthase activity
EXW33_RS07555	COG1388	LysM domain
EXW33_RS07565	COG0113	porphobilinogen synthase activity
EXW33_RS07570	COG1587	Uroporphyrinogen-III synthase
EXW33_RS07580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW33_RS07590	COG1846	Transcriptional regulator
EXW33_RS07595	COG1764	response to oxidative stress
EXW33_RS07610	COG1067	ATP-dependent peptidase activity
EXW33_RS07610	COG0470	DNA polymerase III
EXW33_RS07655	COG0622	Phosphoesterase
EXW33_RS07670	COG5401	PFAM Sporulation and spore germination
EXW33_RS07685	COG2197	response regulator
EXW33_RS07690	COG2233	PERMEase
EXW33_RS07695	COG0402	S-adenosylhomocysteine deaminase activity
EXW33_RS07700	COG1983	PspC domain protein
EXW33_RS07705	COG1396	sequence-specific DNA binding
EXW33_RS07710	COG0697	spore germination
EXW33_RS07720	COG1959	2 iron, 2 sulfur cluster binding
EXW33_RS07725	COG1668	transmembrane transport
EXW33_RS07730	COG4152	abc transporter atp-binding protein
EXW33_RS07735	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW33_RS07740	COG1360	Flagellar Motor Protein
EXW33_RS07745	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW33_RS07750	COG1876	peptidase activity
EXW33_RS07755	COG0824	Thioesterase
EXW33_RS07760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW33_RS07765	COG1053	succinate dehydrogenase
EXW33_RS07770	COG2009	succinate dehydrogenase
EXW33_RS07775	COG1719	4-vinyl reductase, 4VR
EXW33_RS07780	COG0322	excinuclease ABC activity
EXW33_RS07785	COG3118	belongs to the thioredoxin family
EXW33_RS07790	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW33_RS07795	COG2086	electron transfer activity
EXW33_RS07800	COG1024	Enoyl-CoA hydratase
EXW33_RS07805	COG1309	transcriptional regulator
EXW33_RS07810	COG0318	PFAM AMP-dependent synthetase and ligase
EXW33_RS07840	COG2318	DinB family
EXW33_RS07865	COG4974	Belongs to the 'phage' integrase family
EXW33_RS07900	COG1131	(ABC) transporter
EXW33_RS07905	COG2205	protein histidine kinase activity
EXW33_RS07910	COG0745	RESPONSE REGULATOR receiver
EXW33_RS07920	COG4895	conserved protein (DUF2196)
EXW33_RS07925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW33_RS07935	COG4509	Sortase family
EXW33_RS07940	COG1120	ATPase activity
EXW33_RS07955	COG5386	Cell surface protein
EXW33_RS07965	COG5386	Cell surface protein
EXW33_RS07970	COG1114	Component of the transport system for branched-chain amino acids
EXW33_RS07975	COG1187	pseudouridine synthase activity
EXW33_RS07985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW33_RS07985	COG1796	DNA polymerase
EXW33_RS07990	COG1286	toxin biosynthetic process
EXW33_RS07995	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW33_RS08000	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW33_RS08030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW33_RS08040	COG1418	mRNA catabolic process
EXW33_RS08060	COG2814	Major facilitator Superfamily
EXW33_RS08065	COG1566	PFAM secretion protein HlyD family protein
EXW33_RS08070	COG1309	transcriptional regulator
EXW33_RS08075	COG1363	Peptidase, m42
EXW33_RS08100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW33_RS08110	COG1484	DNA-dependent DNA replication
EXW33_RS08115	COG3611	Membrane attachment protein
EXW33_RS08125	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW33_RS08130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW33_RS08135	COG0237	dephospho-CoA kinase activity
EXW33_RS08140	COG1971	Probably functions as a manganese efflux pump
EXW33_RS08150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW33_RS08150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW33_RS08155	COG5002	protein histidine kinase activity
EXW33_RS08160	COG0745	RESPONSE REGULATOR receiver
EXW33_RS08180	COG0538	isocitrate dehydrogenase activity
EXW33_RS08185	COG0372	Belongs to the citrate synthase family
EXW33_RS08195	COG0628	permease
EXW33_RS08200	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW33_RS08225	COG1725	Transcriptional regulator
EXW33_RS08230	COG0281	malic enzyme
EXW33_RS08235	COG0587	DNA-directed DNA polymerase activity
EXW33_RS08250	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW33_RS08265	COG4109	DRTGG domain
EXW33_RS08280	COG0006	proline dipeptidase activity
EXW33_RS08325	COG0662	Cupin 2, conserved barrel domain protein
EXW33_RS08340	COG1028	Short-chain dehydrogenase reductase Sdr
EXW33_RS08345	COG0589	response to stress
EXW33_RS08350	COG0346	lactoylglutathione lyase activity
EXW33_RS08390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW33_RS08415	COG0827	DNA restriction-modification system
EXW33_RS08420	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW33_RS08425	COG3874	Sporulation protein YtfJ
EXW33_RS08440	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW33_RS08450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW33_RS08465	COG1104	cysteine desulfurase activity
EXW33_RS08470	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW33_RS08475	COG0583	DNA-binding transcription factor activity
EXW33_RS08480	COG0697	spore germination
EXW33_RS08485	COG1309	transcriptional regulator
EXW33_RS08490	COG1956	GAF domain-containing protein
EXW33_RS08495	COG0626	cystathionine gamma-synthase activity
EXW33_RS08530	COG1595	DNA-templated transcription, initiation
EXW33_RS08540	COG0110	maltose O-acetyltransferase activity
EXW33_RS08545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW33_RS08550	COG0454	-acetyltransferase
EXW33_RS08555	COG0517	IMP dehydrogenase activity
EXW33_RS08560	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW33_RS08575	COG0745	RESPONSE REGULATOR receiver
EXW33_RS08580	COG5002	protein histidine kinase activity
EXW33_RS08585	COG0666	response to abiotic stimulus
EXW33_RS08615	COG1609	Transcriptional regulator
EXW33_RS08625	COG4851	CamS sex pheromone cAM373 precursor
EXW33_RS08630	COG3118	belongs to the thioredoxin family
EXW33_RS08640	COG2309	aminopeptidase activity
EXW33_RS08665	COG0697	spore germination
EXW33_RS08670	COG0789	Transcriptional regulator
EXW33_RS08685	COG1674	ftsk spoiiie
EXW33_RS08690	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW33_RS08690	COG1388	LysM domain
EXW33_RS08700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW33_RS08705	COG4848	Belongs to the UPF0354 family
EXW33_RS08710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW33_RS08715	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW33_RS08720	COG1363	Peptidase, m42
EXW33_RS08730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW33_RS08745	COG0510	thiamine kinase activity
EXW33_RS08750	COG1523	belongs to the glycosyl hydrolase 13 family
EXW33_RS08760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW33_RS08765	COG1349	DNA-binding transcription factor activity
EXW33_RS08770	COG1187	pseudouridine synthase activity
EXW33_RS08775	COG2244	polysaccharide biosynthetic process
EXW33_RS08780	COG2081	HI0933 family
EXW33_RS08785	COG2814	Major facilitator Superfamily
EXW33_RS08795	COG3832	glyoxalase III activity
EXW33_RS08815	COG1329	Transcriptional regulator
EXW33_RS08840	COG0314	molybdopterin synthase activity
EXW33_RS08845	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW33_RS08850	COG0303	'Molybdopterin
EXW33_RS08860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW33_RS08865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW33_RS08885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW33_RS08895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW33_RS08940	COG2814	Major facilitator Superfamily
EXW33_RS08945	COG0475	glutathione-regulated potassium exporter activity
EXW33_RS08950	COG0490	domain, Protein
EXW33_RS08955	COG0582	viral genome integration into host DNA
EXW33_RS08970	COG1136	(ABC) transporter
EXW33_RS08990	COG1242	4 iron, 4 sulfur cluster binding
EXW33_RS08995	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW33_RS09000	COG1794	racemase activity, acting on amino acids and derivatives
EXW33_RS09015	COG2267	carboxylic ester hydrolase activity
EXW33_RS09020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW33_RS09025	COG0671	phosphoesterase, PA-phosphatase related
EXW33_RS09090	COG3852	Histidine kinase
EXW33_RS09095	COG3852	Histidine kinase
EXW33_RS09105	COG2267	carboxylic ester hydrolase activity
EXW33_RS09110	COG1368	sulfuric ester hydrolase activity
EXW33_RS09125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW33_RS09130	COG1116	anion transmembrane transporter activity
EXW33_RS09135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW33_RS09160	COG0494	nUDIX hydrolase
EXW33_RS09185	COG1854	S-ribosylhomocysteine lyase activity
EXW33_RS09195	COG0288	reversible hydration of carbon dioxide
EXW33_RS09200	COG1271	oxidase subunit
EXW33_RS09205	COG1294	oxidase, subunit
EXW33_RS09220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW33_RS09245	COG1842	Phage shock protein A
EXW33_RS09275	COG5002	protein histidine kinase activity
EXW33_RS09280	COG0745	RESPONSE REGULATOR receiver
EXW33_RS09305	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW33_RS09310	COG1597	lipid kinase activity
EXW33_RS09340	COG0577	efflux transmembrane transporter activity
EXW33_RS09345	COG1136	(ABC) transporter
EXW33_RS09360	COG0586	Pfam SNARE associated Golgi protein
EXW33_RS09365	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW33_RS09370	COG0577	efflux transmembrane transporter activity
EXW33_RS09375	COG1136	(ABC) transporter
EXW33_RS09380	COG3708	Transcriptional regulator
EXW33_RS09380	COG2207	Transcriptional regulator
EXW33_RS09390	COG1131	(ABC) transporter
EXW33_RS09395	COG5658	integral membrane protein
EXW33_RS09400	COG0640	Transcriptional regulator
EXW33_RS09410	COG1595	DNA-templated transcription, initiation
EXW33_RS09415	COG0745	RESPONSE REGULATOR receiver
EXW33_RS09420	COG2205	protein histidine kinase activity
EXW33_RS09425	COG0577	efflux transmembrane transporter activity
EXW33_RS09430	COG0577	efflux transmembrane transporter activity
EXW33_RS09435	COG1136	(ABC) transporter
EXW33_RS09440	COG0577	efflux transmembrane transporter activity
EXW33_RS09455	COG2188	Transcriptional regulator
EXW33_RS09475	COG3964	amidohydrolase
EXW33_RS09490	COG0745	RESPONSE REGULATOR receiver
EXW33_RS09495	COG4948	Mandelate Racemase Muconate Lactonizing
EXW33_RS09505	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW33_RS09510	COG0596	Alpha beta hydrolase
EXW33_RS09520	COG1169	isochorismate synthase
EXW33_RS09525	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW33_RS09530	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW33_RS09535	COG1278	Cold shock
EXW33_RS09555	COG0058	SHG alpha-glucan phosphorylase activity
EXW33_RS09565	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW33_RS09570	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW33_RS09730	COG1285	pathogenesis
EXW33_RS09735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW33_RS09750	COG2155	Conserved Protein
EXW33_RS09755	COG1098	S1 RNA binding domain
EXW33_RS09760	COG0436	Aminotransferase
EXW33_RS09765	COG1522	sequence-specific DNA binding
EXW33_RS09770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW33_RS09775	COG2267	carboxylic ester hydrolase activity
EXW33_RS09785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW33_RS09805	COG5018	Exonuclease
EXW33_RS09810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW33_RS09830	COG2050	protein possibly involved in aromatic compounds catabolism
EXW33_RS09840	COG1268	BioY protein
EXW33_RS09845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW33_RS09850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW33_RS09865	COG3584	3D domain protein
EXW33_RS09880	COG1252	NADH dehydrogenase
EXW33_RS09890	COG3708	Transcriptional regulator
EXW33_RS09905	COG1683	Conserved Protein
EXW33_RS09925	COG0316	Belongs to the HesB IscA family
EXW33_RS09940	COG1252	NADH dehydrogenase
EXW33_RS09950	COG2274	protein secretion by the type I secretion system
EXW33_RS09955	COG0390	transport system, permease component
EXW33_RS09960	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW33_RS09990	COG4837	Protein of unknown function (DUF1462)
EXW33_RS09995	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW33_RS10005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW33_RS10010	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW33_RS10030	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW33_RS10040	COG0647	UMP catabolic process
EXW33_RS10050	COG2445	Protein of unknown function DUF86
EXW33_RS10055	COG1494	fructose-1,6-bisphosphatase
EXW33_RS10075	COG4470	Protein conserved in bacteria
EXW33_RS10085	COG0789	Transcriptional regulator
EXW33_RS10090	COG4377	Putative membrane peptidase family (DUF2324)
EXW33_RS10115	COG0739	heme binding
EXW33_RS10125	COG3377	Domain of unknown function (DUF1805)
EXW33_RS10130	COG0737	Belongs to the 5'-nucleotidase family
EXW33_RS10135	COG0719	Fe-S assembly protein
EXW33_RS10140	COG0822	iron-sulfur transferase activity
EXW33_RS10145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW33_RS10150	COG0719	Fe-S assembly protein
EXW33_RS10155	COG0396	ATPase activity
EXW33_RS10160	COG1464	Belongs to the NlpA lipoprotein family
EXW33_RS10165	COG1464	Belongs to the NlpA lipoprotein family
EXW33_RS10170	COG2011	ABC-type metal ion transport system permease component
EXW33_RS10185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW33_RS10190	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW33_RS10200	COG1393	Belongs to the ArsC family
EXW33_RS10220	COG0039	L-malate dehydrogenase activity
EXW33_RS10240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW33_RS10245	COG1960	acyl-CoA dehydrogenase activity
EXW33_RS10250	COG0183	Belongs to the thiolase family
EXW33_RS10255	COG1024	Enoyl-CoA hydratase
EXW33_RS10255	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW33_RS10265	COG1686	Belongs to the peptidase S11 family
EXW33_RS10270	COG0506	proline dehydrogenase activity
EXW33_RS10280	COG0011	TIGRFAM Protein of
EXW33_RS10285	COG0840	transmembrane signaling receptor activity
EXW33_RS10300	COG2814	Major facilitator Superfamily
EXW33_RS10305	COG0531	amino acid
EXW33_RS10330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW33_RS10365	COG0586	Pfam SNARE associated Golgi protein
EXW33_RS10375	COG1376	ErfK ybiS ycfS ynhG family protein
EXW33_RS10380	COG0745	RESPONSE REGULATOR receiver
EXW33_RS10385	COG5002	protein histidine kinase activity
EXW33_RS10395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW33_RS10405	COG0840	transmembrane signaling receptor activity
EXW33_RS10410	COG0840	transmembrane signaling receptor activity
EXW33_RS10415	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW33_RS10420	COG3227	Zinc metalloprotease (Elastase)
EXW33_RS10440	COG0586	Pfam SNARE associated Golgi protein
EXW33_RS10445	COG0475	glutathione-regulated potassium exporter activity
EXW33_RS10450	COG0490	domain, Protein
EXW33_RS10455	COG1115	amino acid carrier protein
EXW33_RS10460	COG0783	Belongs to the Dps family
EXW33_RS10475	COG1611	Belongs to the LOG family
EXW33_RS10485	COG1528	Iron-storage protein
EXW33_RS10490	COG2311	Membrane
EXW33_RS10495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW33_RS10500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW33_RS10505	COG1115	amino acid carrier protein
EXW33_RS10510	COG1115	amino acid carrier protein
EXW33_RS10515	COG2910	NAD(P)H-binding
EXW33_RS10530	COG0656	L-ascorbic acid biosynthetic process
EXW33_RS10535	COG2814	Major facilitator Superfamily
EXW33_RS10540	COG1733	regulation of RNA biosynthetic process
EXW33_RS10550	COG1252	NADH dehydrogenase
EXW33_RS10555	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EXW33_RS10570	COG3290	protein histidine kinase activity
EXW33_RS10570	COG0840	transmembrane signaling receptor activity
EXW33_RS10580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW33_RS10605	COG0488	(ABC) transporter
EXW33_RS10610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW33_RS10625	COG1335	isochorismatase
EXW33_RS10630	COG1522	sequence-specific DNA binding
EXW33_RS10640	COG1522	sequence-specific DNA binding
EXW33_RS10645	COG0288	reversible hydration of carbon dioxide
EXW33_RS10650	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW33_RS10655	COG2233	PERMEase
EXW33_RS10700	COG0557	exoribonuclease II activity
EXW33_RS10705	COG1647	Serine aminopeptidase, S33
EXW33_RS10710	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW33_RS10715	COG1346	cytolysis
EXW33_RS10750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW33_RS10765	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW33_RS10800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW33_RS10815	COG2323	membrane
EXW33_RS10825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW33_RS10835	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW33_RS10845	COG1051	belongs to the nudix hydrolase family
EXW33_RS10855	COG0492	ferredoxin-NADP+ reductase activity
EXW33_RS10860	COG0457	Tetratricopeptide repeat
EXW33_RS10865	COG0110	maltose O-acetyltransferase activity
EXW33_RS10885	COG1950	PFAM Membrane protein of
EXW33_RS10895	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW33_RS10900	COG0556	nucleotide-excision repair
EXW33_RS10910	COG0789	Transcriptional regulator
EXW33_RS10930	COG0583	DNA-binding transcription factor activity
EXW33_RS10940	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW33_RS10945	COG0488	(ABC) transporter
EXW33_RS10955	COG1132	(ABC) transporter
EXW33_RS10960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW33_RS10965	COG0793	Belongs to the peptidase S41A family
EXW33_RS10965	COG3409	Peptidoglycan-binding domain 1 protein
EXW33_RS10970	COG2177	Part of the ABC transporter FtsEX involved in
EXW33_RS10975	COG2884	Cell division ATP-binding protein ftsE
EXW33_RS10995	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EXW33_RS11000	COG1278	Cold shock
EXW33_RS11005	COG1040	competence protein
EXW33_RS11010	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW33_RS11020	COG1733	regulation of RNA biosynthetic process
EXW33_RS11025	COG1307	EDD domain protein, DegV family
EXW33_RS11030	COG1739	Uncharacterized protein family UPF0029
EXW33_RS11035	COG1316	TRANSCRIPTIONal
EXW33_RS11040	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW33_RS11045	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW33_RS11050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW33_RS11060	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW33_RS11060	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW33_RS11080	COG1486	melibiose metabolic process
EXW33_RS11085	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW33_RS11090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW33_RS11115	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW33_RS11125	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW33_RS11130	COG1301	dicarboxylic acid transport
EXW33_RS11140	COG0346	lactoylglutathione lyase activity
EXW33_RS11145	COG1511	domain protein
EXW33_RS11150	COG0583	DNA-binding transcription factor activity
EXW33_RS11155	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW33_RS11165	COG1271	oxidase subunit
EXW33_RS11170	COG1294	oxidase, subunit
EXW33_RS11175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW33_RS11185	COG1620	l-lactate permease
EXW33_RS11195	COG2389	metal-binding protein
EXW33_RS11205	COG1368	sulfuric ester hydrolase activity
EXW33_RS11215	COG0791	NLP P60 protein
EXW33_RS11215	COG1388	LysM domain
EXW33_RS11220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW33_RS11230	COG1215	transferase activity, transferring glycosyl groups
EXW33_RS11235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW33_RS11240	COG3584	3D domain protein
EXW33_RS11240	COG1388	LysM domain
EXW33_RS11250	COG4715	Zinc finger, swim domain protein
EXW33_RS11255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW33_RS11295	COG0577	efflux transmembrane transporter activity
EXW33_RS11300	COG1136	(ABC) transporter
EXW33_RS11325	COG3850	Histidine kinase
EXW33_RS11325	COG5002	protein histidine kinase activity
EXW33_RS11330	COG0745	RESPONSE REGULATOR receiver
EXW33_RS11335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW33_RS11340	COG4750	Nucleotidyl transferase
EXW33_RS11345	COG0697	spore germination
EXW33_RS11355	COG3475	LICD family
EXW33_RS11365	COG1316	TRANSCRIPTIONal
EXW33_RS11370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW33_RS11375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW33_RS11380	COG1215	transferase activity, transferring glycosyl groups
EXW33_RS11405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW33_RS11410	COG4464	protein tyrosine phosphatase activity
EXW33_RS11415	COG0489	protein tyrosine kinase activity
EXW33_RS11420	COG3944	biosynthesis protein
EXW33_RS11425	COG0489	protein tyrosine kinase activity
EXW33_RS11440	COG1609	Transcriptional regulator
EXW33_RS11450	COG0739	heme binding
EXW33_RS11465	COG3279	Response regulator of the LytR AlgR family
EXW33_RS11470	COG2385	sporulation resulting in formation of a cellular spore
EXW33_RS11485	COG4836	Membrane
EXW33_RS11490	COG1007	ATP synthesis coupled electron transport
EXW33_RS11495	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW33_RS11500	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW33_RS11510	COG0839	Belongs to the complex I subunit 6 family
EXW33_RS11530	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW33_RS11575	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW33_RS11595	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW33_RS11630	COG0698	ribose 5-phosphate isomerase
EXW33_RS11640	COG2190	(PTS) system
EXW33_RS11645	COG2259	Doxx family
EXW33_RS11650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW33_RS11665	COG0009	L-threonylcarbamoyladenylate synthase
EXW33_RS11685	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW33_RS11700	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW33_RS11705	COG1494	fructose-1,6-bisphosphatase
EXW33_RS11725	COG4821	SIS domain
EXW33_RS11730	COG0504	CTP synthase activity
EXW33_RS11745	COG1960	acyl-CoA dehydrogenase activity
EXW33_RS11750	COG1960	acyl-CoA dehydrogenase activity
EXW33_RS11755	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW33_RS11765	COG2181	nitrate reductase activity
EXW33_RS11765	COG0247	lactate metabolic process
EXW33_RS11770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW33_RS11780	COG3300	MHYT domain
EXW33_RS11780	COG5001	Diguanylate cyclase
EXW33_RS11795	COG3227	Zinc metalloprotease (Elastase)
EXW33_RS11800	COG2197	response regulator
EXW33_RS11805	COG4585	Histidine kinase
EXW33_RS11810	COG0842	Transport permease protein
EXW33_RS11815	COG1131	(ABC) transporter
EXW33_RS11820	COG0024	Methionine aminopeptidase
EXW33_RS11825	COG2234	aminopeptidase activity
EXW33_RS11840	COG4506	Protein conserved in bacteria
EXW33_RS11845	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW33_RS11865	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW33_RS11870	COG2814	Major facilitator Superfamily
EXW33_RS11875	COG0789	Transcriptional regulator
EXW33_RS11880	COG0584	glycerophosphoryl diester phosphodiesterase
EXW33_RS11885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW33_RS11895	COG1994	Peptidase M50
EXW33_RS11905	COG1078	dGTPase activity
EXW33_RS11910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW33_RS11915	COG1120	ATPase activity
EXW33_RS11920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW33_RS11925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW33_RS11930	COG4844	belongs to the
EXW33_RS11945	COG0280	phosphate acetyltransferase
EXW33_RS11960	COG3773	Cell wall hydrolase
EXW33_RS11970	COG2363	Small membrane protein
EXW33_RS11980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW33_RS11985	COG2233	PERMEase
EXW33_RS11990	COG0561	phosphatase activity
EXW33_RS11995	COG2814	Major facilitator Superfamily
EXW33_RS12005	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW33_RS12010	COG1131	(ABC) transporter
EXW33_RS12015	COG2755	lipolytic protein G-D-S-L family
EXW33_RS12020	COG1609	Transcriptional regulator
EXW33_RS12030	COG0460	homoserine dehydrogenase
EXW33_RS12040	COG2873	o-acetylhomoserine
EXW33_RS12050	COG1011	Hydrolase
EXW33_RS12055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW33_RS12065	COG2197	response regulator
EXW33_RS12070	COG2203	Gaf domain
EXW33_RS12070	COG4585	Histidine kinase
EXW33_RS12075	COG0351	phosphomethylpyrimidine kinase
EXW33_RS12080	COG3706	GGDEF domain
EXW33_RS12085	COG2879	small protein
EXW33_RS12090	COG1966	Carbon starvation protein
EXW33_RS12095	COG3279	Response regulator of the LytR AlgR family
EXW33_RS12100	COG0477	Major facilitator Superfamily
EXW33_RS12110	COG0438	transferase activity, transferring glycosyl groups
EXW33_RS12125	COG0840	transmembrane signaling receptor activity
EXW33_RS12135	COG1607	acyl-coa hydrolase
EXW33_RS12145	COG1215	transferase activity, transferring glycosyl groups
EXW33_RS12155	COG1309	transcriptional regulator
EXW33_RS12160	COG0488	(ABC) transporter
EXW33_RS12175	COG0463	Glycosyl transferase, family 2
EXW33_RS12180	COG1309	transcriptional regulator
EXW33_RS12185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW33_RS12190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW33_RS12190	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW33_RS12195	COG0628	permease
EXW33_RS12215	COG3275	phosphorelay sensor kinase activity
EXW33_RS12220	COG2814	Major facilitator Superfamily
EXW33_RS12225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW33_RS12230	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW33_RS12255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW33_RS12260	COG1272	protein, Hemolysin III
EXW33_RS12285	COG1164	Oligoendopeptidase f
EXW33_RS12305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW33_RS12310	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW33_RS12315	COG4853	Protein conserved in bacteria
EXW33_RS12325	COG5002	protein histidine kinase activity
EXW33_RS12330	COG0745	RESPONSE REGULATOR receiver
EXW33_RS12360	COG0305	Participates in initiation and elongation during chromosome replication
EXW33_RS12370	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW33_RS12375	COG4241	membrane
EXW33_RS12385	COG0629	single-stranded DNA binding
EXW33_RS12395	COG0012	GTP binding
EXW33_RS12400	COG4481	Protein conserved in bacteria
EXW33_RS12405	COG0668	transmembrane transport
EXW33_RS12415	COG1475	DNA binding
EXW33_RS12420	COG1192	Involved in chromosome partitioning
EXW33_RS12445	COG1847	R3H domain protein
EXW33_RS12450	COG0706	membrane insertase activity
EXW33_RS12460	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW33_RS12470	COG0592	DNA-directed DNA polymerase activity
EXW33_RS12475	COG2501	S4 domain
EXW33_RS12485	COG0187	DNA topoisomerase II activity
EXW33_RS12490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW33_RS12525	COG0517	IMP dehydrogenase activity
EXW33_RS12525	COG0516	GMP reductase activity
EXW33_RS12530	COG1686	Belongs to the peptidase S11 family
EXW33_RS12560	COG1428	Deoxynucleoside kinase
EXW33_RS12565	COG1428	Deoxynucleoside kinase
EXW33_RS12570	COG1335	isochorismatase
EXW33_RS12575	COG0590	tRNA wobble adenosine to inosine editing
EXW33_RS12585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW33_RS12640	COG1982	Orn Lys Arg decarboxylase major
EXW33_RS12650	COG0470	DNA polymerase III
EXW33_RS12655	COG1774	PSP1 C-terminal conserved region
EXW33_RS12665	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW33_RS12675	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW33_RS12680	COG2002	toxin-antitoxin pair type II binding
EXW33_RS12690	COG0084	hydrolase, TatD family'
EXW33_RS12700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW33_RS12710	COG4466	Protein conserved in bacteria
EXW33_RS12725	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW33_RS12730	COG0251	oxidation-reduction process
EXW33_RS12735	COG2088	sporulation resulting in formation of a cellular spore
EXW33_RS12760	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW33_RS12765	COG2002	toxin-antitoxin pair type II binding
EXW33_RS12770	COG2244	polysaccharide biosynthetic process
EXW33_RS12775	COG3956	TIGRFAM MazG family protein
EXW33_RS12780	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW33_RS12800	COG1098	S1 RNA binding domain
EXW33_RS12815	COG2208	phosphoserine phosphatase activity
EXW33_RS12825	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW33_RS12830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW33_RS12845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW33_RS12850	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW33_RS12855	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW33_RS12860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW33_RS12865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW33_RS12870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW33_RS12875	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW33_RS12880	COG1396	sequence-specific DNA binding
EXW33_RS12885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW33_RS12975	COG3880	PFAM UvrB UvrC protein
EXW33_RS12985	COG0542	response to heat
EXW33_RS12990	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW33_RS13000	COG4956	integral membrane protein (PIN domain superfamily)
EXW33_RS13020	COG1045	serine acetyltransferase
EXW33_RS13035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW33_RS13040	COG3688	RNA-binding protein containing a PIN domain
EXW33_RS13050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW33_RS13055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW33_RS13060	COG0250	Participates in transcription elongation, termination and antitermination
EXW33_RS13065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW33_RS13070	COG0081	regulation of translation
EXW33_RS13080	COG0222	ribosome binding
EXW33_RS13085	COG2813	Specifically methylates the guanine in position
EXW33_RS13100	COG1358	cellular component organization or biogenesis
EXW33_RS13105	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW33_RS13125	COG0051	transcription antitermination factor activity, RNA binding
EXW33_RS13130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW33_RS13170	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW33_RS13220	COG1841	ribosomal large subunit assembly
EXW33_RS13230	COG0201	protein transport
EXW33_RS13240	COG0024	Methionine aminopeptidase
EXW33_RS13250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW33_RS13285	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW33_RS13310	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW33_RS13315	COG0489	protein tyrosine kinase activity
EXW33_RS13325	COG2194	sulfuric ester hydrolase activity
EXW33_RS13330	COG0726	polysaccharide deacetylase
EXW33_RS13410	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW33_RS13415	COG4856	YbbR-like protein
EXW33_RS13455	COG1028	Short-chain dehydrogenase reductase Sdr
EXW33_RS13460	COG2011	ABC-type metal ion transport system permease component
EXW33_RS13470	COG1464	Belongs to the NlpA lipoprotein family
EXW33_RS13475	COG0604	alcohol dehydrogenase
EXW33_RS13485	COG0277	FAD linked oxidase domain protein
EXW33_RS13490	COG2271	Major facilitator Superfamily
EXW33_RS13500	COG2814	Major facilitator Superfamily
EXW33_RS13515	COG0601	transmembrane transport
EXW33_RS13520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW33_RS13525	COG0444	Belongs to the ABC transporter superfamily
EXW33_RS13530	COG4608	Belongs to the ABC transporter superfamily
EXW33_RS13535	COG4166	transmembrane transport
EXW33_RS13545	COG2207	Transcriptional regulator
EXW33_RS13555	COG4166	transmembrane transport
EXW33_RS13560	COG4166	transmembrane transport
EXW33_RS13565	COG0656	L-ascorbic acid biosynthetic process
EXW33_RS13585	COG4149	molybdate abc transporter
EXW33_RS13590	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW33_RS13595	COG1910	domain protein
EXW33_RS13610	COG0697	spore germination
EXW33_RS13625	COG0204	Acyl-transferase
EXW33_RS13635	COG1609	Transcriptional regulator
EXW33_RS13645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW33_RS13660	COG5298	Protein conserved in bacteria
EXW33_RS13680	COG0488	(ABC) transporter
EXW33_RS13690	COG0747	negative chemotaxis
EXW33_RS13695	COG0601	transmembrane transport
EXW33_RS13700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW33_RS13705	COG0444	Belongs to the ABC transporter superfamily
EXW33_RS13710	COG4608	Belongs to the ABC transporter superfamily
EXW33_RS13715	COG0561	phosphatase activity
EXW33_RS13740	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW33_RS13745	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW33_RS13755	COG0531	amino acid
EXW33_RS13760	COG2814	Major facilitator Superfamily
EXW33_RS13770	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW33_RS13780	COG4294	response to UV
EXW33_RS13785	COG0705	Rhomboid family
EXW33_RS13795	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW33_RS13800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW33_RS13805	COG0864	Transcriptional regulator
EXW33_RS13810	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW33_RS13815	COG2183	response to ionizing radiation
EXW33_RS13915	COG0802	atpase or kinase
EXW33_RS13920	COG1214	PFAM Peptidase M22, glycoprotease
EXW33_RS13925	COG0456	acetyltransferase
EXW33_RS13935	COG0488	(ABC) transporter
EXW33_RS13950	COG1266	CAAX protease self-immunity
EXW33_RS13960	COG0459	protein refolding
EXW33_RS13975	COG2252	PERMEase
EXW33_RS13985	COG5002	protein histidine kinase activity
EXW33_RS14010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW33_RS14050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW33_RS14060	COG1215	transferase activity, transferring glycosyl groups
EXW33_RS14080	COG0697	spore germination
EXW33_RS14125	COG2205	protein histidine kinase activity
EXW33_RS14130	COG0745	RESPONSE REGULATOR receiver
EXW33_RS14150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW33_RS14155	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW33_RS14160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW33_RS14170	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW33_RS14185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW33_RS14195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW33_RS14200	COG0138	bifunctional purine biosynthesis protein purh
EXW33_RS14205	COG0151	Belongs to the GarS family
EXW33_RS14230	COG0210	DNA helicase
EXW33_RS14240	COG4851	CamS sex pheromone cAM373 precursor
EXW33_RS14255	COG1335	isochorismatase
EXW33_RS14265	COG2011	ABC-type metal ion transport system permease component
EXW33_RS14270	COG1464	Belongs to the NlpA lipoprotein family
EXW33_RS14285	COG0003	Pfam Anion-transporting ATPase
EXW33_RS14290	COG1846	Transcriptional regulator
EXW33_RS14295	COG4682	membrane
EXW33_RS14315	COG1597	lipid kinase activity
EXW33_RS14320	COG0546	phosphoglycolate phosphatase activity
EXW33_RS14325	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW33_RS14335	COG1012	belongs to the aldehyde dehydrogenase family
EXW33_RS14340	COG2076	Multidrug Resistance protein
EXW33_RS14350	COG2309	aminopeptidase activity
EXW33_RS14365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW33_RS14375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW33_RS14380	COG5002	protein histidine kinase activity
EXW33_RS14390	COG4807	Protein conserved in bacteria
EXW33_RS14415	COG1757	Na H antiporter
EXW33_RS14420	COG1473	amidohydrolase
EXW33_RS14435	COG0450	alkyl hydroperoxide reductase
EXW33_RS14455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW33_RS14460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW33_RS14465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW33_RS14470	COG0492	ferredoxin-NADP+ reductase activity
EXW33_RS14480	COG0166	Belongs to the GPI family
EXW33_RS14505	COG5002	protein histidine kinase activity
EXW33_RS14525	COG3541	Predicted nucleotidyltransferase
EXW33_RS14530	COG2814	Major facilitator Superfamily
EXW33_RS14535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW33_RS14535	COG0723	plastoquinol--plastocyanin reductase activity
EXW33_RS14545	COG0765	amino acid transport
EXW33_RS14550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW33_RS14560	COG0840	transmembrane signaling receptor activity
EXW33_RS14585	COG0549	Belongs to the carbamate kinase family
EXW33_RS14600	COG0277	FAD linked oxidase domain protein
EXW33_RS14605	COG0366	Alpha amylase catalytic
EXW33_RS14610	COG2190	(PTS) system
EXW33_RS14610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW33_RS14610	COG1263	PTS System
EXW33_RS14640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW33_RS14645	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW33_RS14665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW33_RS14675	COG1116	anion transmembrane transporter activity
EXW33_RS14720	COG2270	Major facilitator Superfamily
EXW33_RS14745	COG4193	domain, Protein
EXW33_RS14745	COG4193	domain, Protein
EXW33_RS14755	COG2310	stress, protein
EXW33_RS14760	COG2310	stress, protein
EXW33_RS14765	COG2310	stress, protein
EXW33_RS14770	COG0861	Integral membrane protein TerC family
EXW33_RS14780	COG3853	Toxic anion resistance protein (TelA)
EXW33_RS14795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW33_RS14805	COG1295	ribonuclease BN
EXW33_RS14810	COG2217	Heavy metal translocating P-type atpase
EXW33_RS14815	COG0697	spore germination
EXW33_RS14835	COG0586	Pfam SNARE associated Golgi protein
EXW33_RS14850	COG3871	stress protein (general stress protein 26)
EXW33_RS14855	COG0387	Pfam Sodium calcium exchanger
EXW33_RS14865	COG0535	radical SAM domain protein
EXW33_RS14885	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW33_RS14905	COG3829	transcription factor binding
EXW33_RS14915	COG0833	amino acid
EXW33_RS14920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW33_RS14945	COG1263	PTS System
EXW33_RS14945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW33_RS14950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW33_RS14970	COG0463	Glycosyl transferase, family 2
EXW33_RS14980	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW33_RS14980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW33_RS14985	COG0463	Glycosyl transferase, family 2
EXW33_RS14990	COG1882	Formate acetyltransferase
EXW33_RS14995	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW33_RS15015	COG1228	amidohydrolase
EXW33_RS15020	COG1090	epimerase
EXW33_RS15050	COG1988	membrane-bound metal-dependent
EXW33_RS15055	COG1194	a g-specific adenine glycosylase
EXW33_RS15075	COG3557	Belongs to the UPF0374 family
EXW33_RS15080	COG1132	(ABC) transporter
EXW33_RS15085	COG4129	membrane
EXW33_RS15090	COG0069	glutamate synthase activity
EXW33_RS15090	COG0070	glutamate synthase
EXW33_RS15090	COG0067	glutamate synthase
EXW33_RS15095	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW33_RS15100	COG4555	ABC transporter
EXW33_RS15120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW33_RS15125	COG0735	belongs to the Fur family
EXW33_RS15245	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW33_RS15270	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW33_RS15275	COG5001	Diguanylate cyclase
EXW33_RS15275	COG1716	ATPase activity
EXW33_RS15280	COG2766	serine protein kinase
EXW33_RS15285	COG2718	Belongs to the UPF0229 family
EXW33_RS15300	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW33_RS15305	COG2268	Band 7 protein
EXW33_RS15315	COG3290	protein histidine kinase activity
EXW33_RS15320	COG4565	transcriptional regulatory protein
EXW33_RS15325	COG2851	Citrate transporter
EXW33_RS15350	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW33_RS15355	COG3842	ATPase activity
EXW33_RS15360	COG1175	transmembrane transport
EXW33_RS15365	COG0395	ABC-type sugar transport system, permease component
EXW33_RS15375	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW33_RS15380	COG0745	RESPONSE REGULATOR receiver
EXW33_RS15385	COG5002	protein histidine kinase activity
EXW33_RS15395	COG4990	cell redox homeostasis
EXW33_RS15405	COG3290	protein histidine kinase activity
EXW33_RS15410	COG4565	transcriptional regulatory protein
EXW33_RS15415	COG3493	citrate carrier protein
EXW33_RS15420	COG0281	malic enzyme
EXW33_RS15430	COG0697	spore germination
EXW33_RS15435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW33_RS15445	COG5002	protein histidine kinase activity
EXW33_RS15450	COG0745	RESPONSE REGULATOR receiver
EXW33_RS15455	COG0454	-acetyltransferase
EXW33_RS15455	COG0456	acetyltransferase
EXW33_RS15460	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW33_RS15465	COG3383	formate dehydrogenase (NAD+) activity
EXW33_RS15485	COG0531	amino acid
EXW33_RS15495	COG0640	Transcriptional regulator
EXW33_RS15500	COG2217	Heavy metal translocating P-type atpase
EXW33_RS15505	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW33_RS15520	COG3227	Zinc metalloprotease (Elastase)
EXW33_RS15540	COG2720	vancomycin resistance protein
EXW33_RS15545	COG1316	TRANSCRIPTIONal
EXW33_RS15550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW33_RS15555	COG0346	lactoylglutathione lyase activity
EXW33_RS15560	COG1253	flavin adenine dinucleotide binding
EXW33_RS15565	COG1027	Aspartate ammonia-lyase
EXW33_RS15570	COG1620	l-lactate permease
EXW33_RS15585	COG3104	oligopeptide transport
EXW33_RS15590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW33_RS15595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW33_RS15600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW33_RS15610	COG2226	methyltransferase
EXW33_RS15620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW33_RS15630	COG4548	von Willebrand factor, type A
EXW33_RS15635	COG0714	Associated with various cellular activities
EXW33_RS15655	COG0531	amino acid
EXW33_RS15660	COG2188	Transcriptional regulator
EXW33_RS15665	COG1263	PTS System
EXW33_RS15665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW33_RS15670	COG0366	Alpha amylase catalytic
EXW33_RS15685	COG0697	spore germination
EXW33_RS15690	COG4585	Histidine kinase
EXW33_RS15695	COG2197	response regulator
EXW33_RS15700	COG1404	Belongs to the peptidase S8 family
EXW33_RS15710	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW33_RS15715	COG1115	amino acid carrier protein
EXW33_RS15720	COG1126	abc transporter atp-binding protein
EXW33_RS15725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW33_RS15730	COG0765	amino acid transport
EXW33_RS15735	COG0765	amino acid transport
EXW33_RS15740	COG0833	amino acid
EXW33_RS15765	COG2378	regulation of single-species biofilm formation
EXW33_RS15770	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW33_RS15775	COG5002	protein histidine kinase activity
EXW33_RS15790	COG0659	secondary active sulfate transmembrane transporter activity
EXW33_RS15805	COG2271	Major facilitator Superfamily
EXW33_RS15810	COG1846	Transcriptional regulator
EXW33_RS15815	COG0477	Major facilitator Superfamily
EXW33_RS15820	COG1609	Transcriptional regulator
EXW33_RS15825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW33_RS15840	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW33_RS15845	COG1879	ABC-type sugar transport system periplasmic component
EXW33_RS15875	COG1063	alcohol dehydrogenase
EXW33_RS15925	COG0840	transmembrane signaling receptor activity
EXW33_RS15930	COG1388	LysM domain
EXW33_RS15930	COG3584	3D domain protein
EXW33_RS15935	COG1476	TRANSCRIPTIONal
EXW33_RS15955	COG3104	oligopeptide transport
EXW33_RS15960	COG1114	Component of the transport system for branched-chain amino acids
EXW33_RS15975	COG1113	amino acid transport
EXW33_RS15980	COG2252	PERMEase
EXW33_RS16005	COG0569	domain protein
EXW33_RS16005	COG0475	glutathione-regulated potassium exporter activity
EXW33_RS16015	COG1845	cytochrome c oxidase, subunit III
EXW33_RS16020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW33_RS16025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EXW33_RS16030	COG0833	amino acid
EXW33_RS16035	COG4990	cell redox homeostasis
EXW33_RS16050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW33_RS16055	COG0697	spore germination
EXW33_RS16060	COG0531	amino acid
EXW33_RS16070	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW33_RS16075	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW33_RS16080	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW33_RS16080	COG1918	ferrous iron import across plasma membrane
EXW33_RS16085	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW33_RS16090	COG0573	inorganic phosphate transmembrane transporter activity
EXW33_RS16095	COG0581	inorganic phosphate transmembrane transporter activity
EXW33_RS16100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW33_RS16220	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW33_RS16240	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW33_RS16245	COG1116	anion transmembrane transporter activity
EXW33_RS16250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW33_RS16255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW33_RS16260	COG0352	thiamine-phosphate diphosphorylase activity
EXW33_RS16265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW33_RS16270	COG2104	thiamine diphosphate biosynthetic process
EXW33_RS16275	COG2022	thiamine diphosphate biosynthetic process
EXW33_RS16280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW33_RS16285	COG0351	phosphomethylpyrimidine kinase
EXW33_RS16310	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW33_RS16315	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW33_RS16320	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW33_RS16325	COG2205	protein histidine kinase activity
EXW33_RS16330	COG2814	Major facilitator Superfamily
EXW33_RS16335	COG1846	Transcriptional regulator
EXW33_RS16350	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW33_RS16355	COG1129	ABC transporter
EXW33_RS16365	COG2252	PERMEase
EXW33_RS16370	COG1028	Short-chain dehydrogenase reductase Sdr
EXW33_RS16430	COG0778	Nitroreductase
EXW33_RS16435	COG2719	SpoVR family
EXW33_RS16460	COG1937	Protein conserved in bacteria
EXW33_RS16465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW33_RS16465	COG0425	Belongs to the sulfur carrier protein TusA family
EXW33_RS16470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW33_RS16470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW33_RS16475	COG0425	Belongs to the sulfur carrier protein TusA family
EXW33_RS16480	COG0425	Belongs to the sulfur carrier protein TusA family
EXW33_RS16480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW33_RS16485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW33_RS16490	COG2210	Belongs to the sulfur carrier protein TusA family
EXW33_RS16495	COG0730	response to heat
EXW33_RS16505	COG1316	TRANSCRIPTIONal
EXW33_RS16510	COG0604	alcohol dehydrogenase
EXW33_RS16515	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW33_RS16520	COG2814	Major facilitator Superfamily
EXW33_RS16530	COG3711	transcriptional antiterminator
EXW33_RS16530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW33_RS16535	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW33_RS16540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW33_RS16560	COG1388	LysM domain
EXW33_RS16560	COG3584	3D domain protein
EXW33_RS16565	COG0577	efflux transmembrane transporter activity
EXW33_RS16570	COG1136	(ABC) transporter
EXW33_RS16580	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW33_RS16595	COG1114	Component of the transport system for branched-chain amino acids
EXW33_RS16600	COG3546	catalase activity
EXW33_RS16635	COG0586	Pfam SNARE associated Golgi protein
EXW33_RS16670	COG0531	amino acid
EXW33_RS16675	COG0475	glutathione-regulated potassium exporter activity
EXW33_RS16685	COG1737	Transcriptional regulator
EXW33_RS16695	COG1263	PTS System
EXW33_RS16695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW33_RS16705	COG2259	Doxx family
EXW33_RS16725	COG1522	sequence-specific DNA binding
EXW33_RS16755	COG2076	Multidrug Resistance protein
EXW33_RS16760	COG1309	transcriptional regulator
EXW33_RS16765	COG2814	Major facilitator Superfamily
EXW33_RS16770	COG1733	regulation of RNA biosynthetic process
EXW33_RS16780	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW33_RS16790	COG4533	DNA binding
EXW33_RS16795	COG2211	Major facilitator Superfamily
EXW33_RS16805	COG0693	protein deglycase activity
EXW33_RS16815	COG0531	amino acid
EXW33_RS16820	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EXW33_RS16825	COG1012	belongs to the aldehyde dehydrogenase family
EXW33_RS16830	COG1132	(ABC) transporter
EXW33_RS16835	COG1132	(ABC) transporter
EXW33_RS16840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW33_RS16845	COG0765	amino acid transport
EXW33_RS16850	COG1126	abc transporter atp-binding protein
EXW33_RS16865	COG0189	ligase activity
EXW33_RS16885	COG0028	Belongs to the TPP enzyme family
EXW33_RS16890	COG3527	Alpha-acetolactate decarboxylase
EXW33_RS16900	COG0561	phosphatase activity
EXW33_RS16910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW33_RS16925	COG0659	secondary active sulfate transmembrane transporter activity
EXW33_RS16935	COG1024	Enoyl-CoA hydratase
EXW33_RS16955	COG1363	Peptidase, m42
EXW33_RS16985	COG0579	oxidoreductase
EXW33_RS17020	COG0601	transmembrane transport
EXW33_RS17025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW33_RS17030	COG0444	Belongs to the ABC transporter superfamily
EXW33_RS17035	COG4608	Belongs to the ABC transporter superfamily
EXW33_RS17210	COG0477	Major facilitator Superfamily
EXW33_RS17215	COG3290	protein histidine kinase activity
EXW33_RS17220	COG4565	transcriptional regulatory protein
EXW33_RS17225	COG3181	Tripartite tricarboxylate transporter family receptor
EXW33_RS17270	COG0305	Participates in initiation and elongation during chromosome replication
EXW33_RS17280	COG1012	belongs to the aldehyde dehydrogenase family
EXW33_RS17295	COG0477	Major facilitator Superfamily
EXW33_RS17335	COG3409	Peptidoglycan-binding domain 1 protein
EXW33_RS17335	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW33_RS17345	COG3711	transcriptional antiterminator
EXW33_RS17350	COG2190	(PTS) system
EXW33_RS17350	COG1263	PTS System
EXW33_RS17350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW33_RS17355	COG2723	6-phospho-beta-galactosidase activity
EXW33_RS17365	COG1183	phosphatidylcholine synthase activity
EXW33_RS17390	COG2814	Major facilitator Superfamily
EXW33_RS17395	COG0640	Transcriptional regulator
EXW33_RS17405	COG2376	Dihydroxyacetone kinase
EXW33_RS17415	COG2376	Dihydroxyacetone kinase
EXW33_RS17425	COG1959	2 iron, 2 sulfur cluster binding
EXW33_RS17440	COG0745	RESPONSE REGULATOR receiver
EXW33_RS17445	COG5002	protein histidine kinase activity
EXW33_RS17445	COG3850	Histidine kinase
EXW33_RS17480	COG3237	CsbD-like
EXW33_RS17505	COG1191	sigma factor activity
EXW33_RS17515	COG2208	phosphoserine phosphatase activity
EXW33_RS17520	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW33_RS17525	COG2198	Histidine kinase
EXW33_RS17525	COG2205	protein histidine kinase activity
EXW33_RS17525	COG0784	Response regulator, receiver
EXW33_RS17555	COG2807	transmembrane transport
EXW33_RS17560	COG2186	Transcriptional regulator
EXW33_RS17595	COG0420	3'-5' exonuclease activity
EXW33_RS17600	COG4717	serine-type aminopeptidase activity
EXW33_RS17625	COG0346	lactoylglutathione lyase activity
EXW33_RS17640	COG0457	Tetratricopeptide repeat
EXW33_RS17650	COG2267	carboxylic ester hydrolase activity
EXW33_RS17660	COG3620	sequence-specific DNA binding
EXW33_RS17665	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW33_RS17670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW33_RS17680	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW33_RS17700	COG3973	AAA domain
EXW33_RS17705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW33_RS17730	COG0537	adenosine 5'-monophosphoramidase activity
EXW33_RS17735	COG1131	(ABC) transporter
EXW33_RS17740	COG4473	ABC transporter
EXW33_RS17755	COG1309	transcriptional regulator
EXW33_RS17765	COG3402	PFAM membrane-flanked domain
EXW33_RS17770	COG3428	Bacterial PH domain
EXW33_RS17810	COG3402	PFAM membrane-flanked domain
EXW33_RS17815	COG3428	Bacterial PH domain
EXW33_RS17820	COG2329	Antibiotic biosynthesis monooxygenase
EXW33_RS17825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW33_RS17840	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW33_RS17865	COG1309	transcriptional regulator
EXW33_RS17870	COG1511	domain protein
EXW33_RS17915	COG1609	Transcriptional regulator
EXW33_RS17925	COG1234	tRNA 3'-trailer cleavage
EXW33_RS17930	COG0095	Lipoate-protein ligase
EXW33_RS17940	COG0318	PFAM AMP-dependent synthetase and ligase
EXW33_RS17965	COG1408	metallophosphoesterase
EXW33_RS17975	COG1078	dGTPase activity
EXW33_RS17985	COG1595	DNA-templated transcription, initiation
EXW33_RS17990	COG3708	Transcriptional regulator
EXW33_RS17990	COG2207	Transcriptional regulator
EXW33_RS18005	COG2205	protein histidine kinase activity
EXW33_RS18010	COG0745	RESPONSE REGULATOR receiver
EXW33_RS18035	COG0501	Belongs to the peptidase M48B family
EXW33_RS18040	COG0840	transmembrane signaling receptor activity
EXW33_RS18045	COG0697	spore germination
EXW33_RS18050	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW33_RS18055	COG2224	Isocitrate lyase
EXW33_RS18085	COG4903	ComK protein
EXW33_RS18090	COG0398	Pfam SNARE associated Golgi protein
EXW33_RS18150	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW33_RS18175	COG0367	asparagine synthase
EXW33_RS18185	COG0753	catalase activity
EXW33_RS18190	COG0004	ammonium transporteR
EXW33_RS18210	COG2996	Protein conserved in bacteria
EXW33_RS18235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW33_RS18250	COG0561	phosphatase activity
EXW33_RS18270	COG2267	carboxylic ester hydrolase activity
EXW33_RS18285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW33_RS18290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW33_RS18295	COG5504	Zn-dependent protease
EXW33_RS18305	COG0180	Tryptophanyl-tRNA synthetase
EXW33_RS18315	COG4166	transmembrane transport
EXW33_RS18320	COG0601	transmembrane transport
EXW33_RS18325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW33_RS18330	COG0444	Belongs to the ABC transporter superfamily
EXW33_RS18335	COG4608	Belongs to the ABC transporter superfamily
EXW33_RS18340	COG0534	Mate efflux family protein
EXW33_RS18345	COG4166	transmembrane transport
EXW33_RS18360	COG0861	Integral membrane protein TerC family
EXW33_RS18370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW33_RS18380	COG1164	Oligoendopeptidase f
EXW33_RS18390	COG2346	COG2346, Truncated hemoglobins
EXW33_RS18395	COG4116	CYTH
EXW33_RS18405	COG2357	RelA SpoT domain protein
EXW33_RS18415	COG0564	pseudouridine synthase activity
EXW33_RS18430	COG0772	Belongs to the SEDS family
EXW33_RS18435	COG1216	Glycosyl transferase, family 2
EXW33_RS18455	COG0457	Tetratricopeptide repeat
EXW33_RS18455	COG0463	Glycosyl transferase, family 2
EXW33_RS18475	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW33_RS18490	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW33_RS18535	COG2153	protein acetylation
EXW33_RS18545	COG2382	esterase
EXW33_RS18550	COG0697	spore germination
EXW33_RS18560	COG5492	domain, Protein
EXW33_RS18565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW33_RS18575	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW33_RS18575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW33_RS18580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW33_RS18595	COG0133	tryptophan synthase activity
EXW33_RS18610	COG1620	l-lactate permease
EXW33_RS18615	COG5634	Uncharacterized conserved protein (DUF2278)
EXW33_RS18680	COG2226	methyltransferase
EXW33_RS18700	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW33_RS18710	COG1476	TRANSCRIPTIONal
EXW33_RS18750	COG4152	abc transporter atp-binding protein
EXW33_RS18755	COG1668	transmembrane transport
EXW33_RS18790	COG1686	Belongs to the peptidase S11 family
EXW33_RS18795	COG0681	Belongs to the peptidase S26 family
EXW33_RS18830	COG1012	belongs to the aldehyde dehydrogenase family
EXW33_RS18840	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW33_RS18845	COG1177	transmembrane transport
EXW33_RS18850	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW33_RS18860	COG2409	Drug exporters of the RND superfamily
EXW33_RS18870	COG0564	pseudouridine synthase activity
EXW33_RS18880	COG2340	Cysteine-rich secretory protein family
EXW33_RS18885	COG0247	lactate metabolic process
EXW33_RS18890	COG0277	FAD linked oxidase domain protein
EXW33_RS18895	COG3835	regulator
EXW33_RS18905	COG0745	RESPONSE REGULATOR receiver
EXW33_RS18910	COG5002	protein histidine kinase activity
EXW33_RS18915	COG2186	Transcriptional regulator
EXW33_RS18935	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW33_RS18945	COG2116	formate transmembrane transporter activity
EXW33_RS18950	COG0861	Integral membrane protein TerC family
EXW33_RS18955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW33_RS18965	COG2030	dehydratase
EXW33_RS18985	COG1028	Short-chain dehydrogenase reductase Sdr
EXW33_RS18990	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW33_RS19000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW33_RS19015	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW33_RS19020	COG3842	ATPase activity
EXW33_RS19045	COG1349	DNA-binding transcription factor activity
EXW33_RS19055	COG0235	Class ii aldolase
EXW33_RS19065	COG2861	carbohydrate metabolic process
EXW33_RS19075	COG3852	Histidine kinase
EXW33_RS19080	COG1846	Transcriptional regulator
EXW33_RS19090	COG2318	DinB family
EXW33_RS19095	COG5002	protein histidine kinase activity
EXW33_RS19105	COG0720	synthase
EXW33_RS19120	COG4873	Protein conserved in bacteria
EXW33_RS19135	COG0456	acetyltransferase
EXW33_RS19150	COG1780	Probably involved in ribonucleotide reductase function
EXW33_RS19165	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW33_RS19175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW33_RS19190	COG2204	response regulator
EXW33_RS19195	COG1012	belongs to the aldehyde dehydrogenase family
EXW33_RS19205	COG1725	Transcriptional regulator
EXW33_RS19210	COG1131	(ABC) transporter
EXW33_RS19220	COG1131	(ABC) transporter
EXW33_RS19225	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW33_RS19230	COG1266	CAAX protease self-immunity
EXW33_RS19240	COG1522	sequence-specific DNA binding
EXW33_RS19260	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW33_RS19265	COG2070	2-Nitropropane dioxygenase
EXW33_RS19270	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW33_RS19280	COG1696	Membrane protein involved in D-alanine export
EXW33_RS19305	COG0716	FMN binding
EXW33_RS19335	COG0534	Mate efflux family protein
EXW33_RS19360	COG1846	Transcriptional regulator
EXW33_RS19370	COG1301	dicarboxylic acid transport
EXW33_RS19375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW33_RS19380	COG4709	membrane
EXW33_RS19385	COG3874	Sporulation protein YtfJ
EXW33_RS19405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW33_RS19410	COG0028	Belongs to the TPP enzyme family
EXW33_RS19415	COG0440	acetolactate synthase activity
EXW33_RS19435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW33_RS19465	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW33_RS19475	COG0107	imidazoleglycerol-phosphate synthase activity
EXW33_RS19485	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW33_RS19490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW33_RS19500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW33_RS19505	COG1183	phosphatidylcholine synthase activity
EXW33_RS19510	COG1368	sulfuric ester hydrolase activity
EXW33_RS19520	COG0019	diaminopimelate decarboxylase activity
EXW33_RS19540	COG0529	Catalyzes the synthesis of activated sulfate
EXW33_RS19545	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW33_RS19565	COG1648	precorrin-2 dehydrogenase activity
EXW33_RS19570	COG0733	neurotransmitter:sodium symporter activity
EXW33_RS19595	COG1757	Na H antiporter
EXW33_RS19610	COG4758	membrane
EXW33_RS19615	COG4585	Histidine kinase
EXW33_RS19620	COG2197	response regulator
EXW33_RS19630	COG1114	Component of the transport system for branched-chain amino acids
EXW33_RS19640	COG2226	methyltransferase
EXW33_RS19680	COG0730	response to heat
EXW33_RS19685	COG0306	phosphate transporter
EXW33_RS19690	COG1392	Phosphate transport regulator
EXW33_RS19695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW33_RS19710	COG3852	Histidine kinase
EXW33_RS19715	COG1801	Protein of unknown function DUF72
EXW33_RS19725	COG0582	viral genome integration into host DNA
EXW33_RS19730	COG5002	protein histidine kinase activity
EXW33_RS19745	COG0392	lysyltransferase activity
EXW33_RS19745	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW33_RS19760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW33_RS19765	COG1686	Belongs to the peptidase S11 family
EXW33_RS19770	COG2715	membrane protein required for spore maturation
EXW33_RS19775	COG0700	Nucleoside recognition
EXW33_RS19780	COG1187	pseudouridine synthase activity
EXW33_RS19790	COG1333	cytochrome c biogenesis protein
EXW33_RS19795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW33_RS19800	COG0745	RESPONSE REGULATOR receiver
EXW33_RS19805	COG5002	protein histidine kinase activity
EXW33_RS19810	COG2096	Adenosyltransferase
EXW33_RS19815	COG4942	peptidase
EXW33_RS19825	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW33_RS19830	COG1141	Ferredoxin
EXW33_RS19835	COG4955	Helix-turn-helix domain
EXW33_RS19840	COG0514	ATP-dependent DNA helicase (RecQ)
EXW33_RS19845	COG1266	CAAX protease self-immunity
EXW33_RS19855	COG1408	metallophosphoesterase
EXW33_RS19860	COG0789	Transcriptional regulator
EXW33_RS19865	COG4862	establishment of competence for transformation
EXW33_RS19870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW33_RS19890	COG0492	ferredoxin-NADP+ reductase activity
EXW33_RS19895	COG0252	asparaginase activity
EXW33_RS19965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW33_RS19980	COG0142	geranyltranstransferase activity
EXW33_RS19990	COG0142	geranyltranstransferase activity
EXW33_RS20015	COG0457	Tetratricopeptide repeat
EXW33_RS20035	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW33_RS20040	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW33_RS20040	COG2010	Cytochrome c
EXW33_RS20045	COG4347	Protein of unknown function (DUF1405)
EXW33_RS20060	COG2738	Putative neutral zinc metallopeptidase
EXW33_RS20070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW33_RS20075	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW33_RS20090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW33_RS20095	COG0438	transferase activity, transferring glycosyl groups
EXW33_RS20130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW33_RS20130	COG1199	ATP-dependent helicase activity
EXW33_RS20150	COG3935	DnaD domain protein
EXW33_RS20155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW33_RS20165	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW33_RS20165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW33_RS20210	COG3599	regulation of cell shape
EXW33_RS20220	COG0116	Belongs to the methyltransferase superfamily
EXW33_RS20230	COG1199	ATP-dependent helicase activity
EXW33_RS20235	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW33_RS20245	COG3173	Aminoglycoside phosphotransferase
EXW33_RS20250	COG0024	Methionine aminopeptidase
EXW33_RS20260	COG2233	PERMEase
EXW33_RS20265	COG2311	Membrane
EXW33_RS20270	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW33_RS20280	COG0456	acetyltransferase
EXW33_RS20320	COG0754	glutathionylspermidine amidase activity
EXW33_RS20335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW33_RS20350	COG0454	-acetyltransferase
EXW33_RS20370	COG0328	RNA-DNA hybrid ribonuclease activity
EXW33_RS20405	COG3403	YqcI/YcgG family
EXW33_RS20410	COG1280	lysine exporter protein (LysE YggA)
EXW33_RS20425	COG3162	membrane
EXW33_RS20430	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW33_RS20435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW33_RS20445	COG0475	glutathione-regulated potassium exporter activity
EXW33_RS20450	COG0789	Transcriptional regulator
EXW33_RS20450	COG4978	Transcriptional regulator
EXW33_RS20460	COG2323	membrane
EXW33_RS20465	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW33_RS20495	COG2814	Major facilitator Superfamily
EXW33_RS20515	COG1923	regulation of RNA biosynthetic process
EXW33_RS20525	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW33_RS20530	COG1360	Flagellar Motor Protein
EXW33_RS20535	COG2201	protein-glutamate methylesterase activity
EXW33_RS20540	COG2198	Histidine kinase
EXW33_RS20540	COG0643	Histidine kinase
EXW33_RS20545	COG1776	CheC inhibitor of MCP methylation
EXW33_RS20545	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW33_RS20560	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW33_RS20580	COG1256	bacterial-type flagellum assembly
EXW33_RS20585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW33_RS20605	COG1815	bacterial-type flagellum-dependent cell motility
EXW33_RS20610	COG1558	bacterial-type flagellum-dependent cell motility
EXW33_RS20620	COG1766	The M ring may be actively involved in energy transduction
EXW33_RS20625	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW33_RS20635	COG1157	protein secretion by the type III secretion system
EXW33_RS20655	COG1749	Flagellar hook protein flgE
EXW33_RS20670	COG0835	chemotaxis
EXW33_RS20670	COG0784	Response regulator, receiver
EXW33_RS20680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW33_RS20685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW33_RS20690	COG0741	lytic transglycosylase activity
EXW33_RS20700	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW33_RS20705	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW33_RS20705	COG1776	CheC inhibitor of MCP methylation
EXW33_RS20715	COG1338	Plays a role in the flagellum-specific transport system
EXW33_RS20720	COG1987	bacterial-type flagellum assembly
EXW33_RS20730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW33_RS20735	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW33_RS20740	COG1419	protein localization to endoplasmic reticulum
EXW33_RS20745	COG4787	bacterial-type flagellum-dependent cell motility
EXW33_RS20750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW33_RS20785	COG2329	Antibiotic biosynthesis monooxygenase
EXW33_RS20800	COG2814	Major facilitator Superfamily
EXW33_RS20810	COG0583	DNA-binding transcription factor activity
EXW33_RS20815	COG3842	ATPase activity
EXW33_RS20820	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW33_RS20830	COG1234	tRNA 3'-trailer cleavage
EXW33_RS20865	COG0406	alpha-ribazole phosphatase activity
EXW33_RS20885	COG1846	Transcriptional regulator
EXW33_RS20895	COG0367	asparagine synthase
EXW33_RS20925	COG1802	Transcriptional regulator
EXW33_RS20930	COG0697	spore germination
EXW33_RS20940	COG0523	cobalamin synthesis protein
EXW33_RS20945	COG0438	transferase activity, transferring glycosyl groups
EXW33_RS20945	COG1216	Glycosyl transferase, family 2
EXW33_RS20950	COG1757	Na H antiporter
EXW33_RS20955	COG0789	Transcriptional regulator
EXW33_RS20960	COG4221	oxidoreductase activity
EXW33_RS20980	COG0534	Mate efflux family protein
EXW33_RS20985	COG3340	Belongs to the peptidase S51 family
EXW33_RS21005	COG0785	Cytochrome C biogenesis protein
EXW33_RS21010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW33_RS21030	COG2733	membrane
EXW33_RS21065	COG1131	(ABC) transporter
EXW33_RS21080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW33_RS21085	COG0528	UMP kinase activity
EXW33_RS21095	COG1027	Aspartate ammonia-lyase
EXW33_RS21100	COG0281	malic enzyme
EXW33_RS21105	COG4191	Histidine kinase
EXW33_RS21110	COG0784	Response regulator, receiver
EXW33_RS21115	COG1846	Transcriptional regulator
EXW33_RS21125	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW33_RS21140	COG3620	sequence-specific DNA binding
EXW33_RS21185	COG1695	Transcriptional regulator
EXW33_RS21195	COG0477	Major facilitator Superfamily
EXW33_RS21200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW33_RS21210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW33_RS21215	COG2223	nitrite transmembrane transporter activity
EXW33_RS21220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW33_RS21235	COG2244	polysaccharide biosynthetic process
EXW33_RS21240	COG0733	neurotransmitter:sodium symporter activity
EXW33_RS21250	COG5566	PFAM Mor transcription activator
EXW33_RS21255	COG2323	membrane
EXW33_RS21275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW33_RS21285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW33_RS21290	COG0028	Belongs to the TPP enzyme family
EXW33_RS21310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW33_RS21330	COG2814	Major facilitator Superfamily
EXW33_RS21335	COG3384	dioxygenase
EXW33_RS21345	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW33_RS21365	COG4166	transmembrane transport
EXW33_RS21375	COG0535	radical SAM domain protein
EXW33_RS21380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW33_RS21400	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW33_RS21415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW33_RS21420	COG0531	amino acid
EXW33_RS21445	COG1266	CAAX protease self-immunity
EXW33_RS21450	COG1309	transcriptional regulator
EXW33_RS21455	COG2390	Transcriptional regulator
EXW33_RS21465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW33_RS21470	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW33_RS21475	COG0295	cytidine deaminase activity
EXW33_RS21505	COG0583	DNA-binding transcription factor activity
EXW33_RS21520	COG0006	proline dipeptidase activity
EXW33_RS21525	COG2132	Multicopper oxidase
EXW33_RS21535	COG1073	alpha beta
EXW33_RS21570	COG1760	l-serine dehydratase
EXW33_RS21575	COG1760	l-serine dehydratase
EXW33_RS21580	COG0814	amino acid
EXW33_RS21590	COG1136	(ABC) transporter
EXW33_RS21595	COG0577	efflux transmembrane transporter activity
EXW33_RS21600	COG0745	RESPONSE REGULATOR receiver
EXW33_RS21605	COG2205	protein histidine kinase activity
EXW33_RS21635	COG0772	Belongs to the SEDS family
EXW33_RS21640	COG2239	Acts as a magnesium transporter
EXW33_RS21650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW33_RS21670	COG1073	alpha beta
EXW33_RS21695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW33_RS21705	COG0583	DNA-binding transcription factor activity
EXW33_RS21725	COG1114	Component of the transport system for branched-chain amino acids
EXW33_RS21735	COG1276	copper resistance
EXW33_RS21735	COG2372	response to copper ion
EXW33_RS21740	COG4549	nuclear export factor GLE1
EXW33_RS21745	COG0697	spore germination
EXW33_RS21750	COG0583	DNA-binding transcription factor activity
EXW33_RS21755	COG1959	2 iron, 2 sulfur cluster binding
EXW33_RS21760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW33_RS21765	COG0778	Nitroreductase
EXW33_RS21775	COG0628	permease
EXW33_RS21790	COG1231	oxidoreductase activity
EXW33_RS21795	COG0523	cobalamin synthesis protein
EXW33_RS21805	COG0411	ABC transporter
EXW33_RS21815	COG0559	Belongs to the binding-protein-dependent transport system permease family
EXW33_RS21825	COG0583	DNA-binding transcription factor activity
EXW33_RS21850	COG1271	oxidase subunit
EXW33_RS21855	COG1294	oxidase, subunit
EXW33_RS21860	COG4988	ABC transporter
EXW33_RS21865	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW33_RS21870	COG1216	Glycosyl transferase, family 2
EXW33_RS21890	COG1686	Belongs to the peptidase S11 family
EXW33_RS21905	COG0791	NLP P60 protein
EXW33_RS21905	COG1388	LysM domain
EXW33_RS21915	COG1132	(ABC) transporter
EXW33_RS21920	COG0745	RESPONSE REGULATOR receiver
EXW33_RS21925	COG5002	protein histidine kinase activity
EXW33_RS21930	COG0300	oxidoreductase activity
EXW33_RS21955	COG5658	integral membrane protein
EXW33_RS21970	COG0460	homoserine dehydrogenase
EXW33_RS21980	COG0083	homoserine kinase activity
EXW33_RS21995	COG1316	TRANSCRIPTIONal
EXW33_RS22005	COG0745	RESPONSE REGULATOR receiver
EXW33_RS22010	COG5002	protein histidine kinase activity
EXW33_RS22025	COG1285	pathogenesis
EXW33_RS22030	COG1247	-acetyltransferase
EXW33_RS22050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW33_RS22060	COG1082	Xylose isomerase domain protein TIM barrel
EXW33_RS22070	COG2814	Major facilitator Superfamily
EXW33_RS22075	COG1279	arginine transmembrane transporter activity
EXW33_RS22080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW33_RS22090	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW33_RS22125	COG0577	efflux transmembrane transporter activity
EXW33_RS22130	COG2002	toxin-antitoxin pair type II binding
EXW33_RS22135	COG1404	Belongs to the peptidase S8 family
EXW33_RS22140	COG0640	Transcriptional regulator
EXW33_RS22145	COG0667	Aldo Keto reductase
EXW33_RS22185	COG3949	Membrane
EXW33_RS22190	COG0783	Belongs to the Dps family
EXW33_RS22205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW33_RS22215	COG1231	oxidoreductase activity
EXW33_RS22220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW33_RS22225	COG4989	oxidoreductase activity
EXW33_RS22230	COG0523	cobalamin synthesis protein
EXW33_RS22240	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW33_RS22250	COG0702	epimerase
EXW33_RS22260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW33_RS22270	COG4166	transmembrane transport
EXW33_RS22275	COG0346	lactoylglutathione lyase activity
EXW33_RS22285	COG0406	alpha-ribazole phosphatase activity
EXW33_RS22295	COG5337	Spore coat protein CotH
EXW33_RS22300	COG1051	belongs to the nudix hydrolase family
EXW33_RS22305	COG0586	Pfam SNARE associated Golgi protein
EXW33_RS22310	COG2244	polysaccharide biosynthetic process
EXW33_RS22320	COG0701	Predicted permease
EXW33_RS22325	COG3689	TIGRFAM TIGR03943 family protein
EXW33_RS22330	COG1607	acyl-coa hydrolase
EXW33_RS22340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW33_RS22355	COG0702	epimerase
EXW33_RS22360	COG2839	Protein conserved in bacteria
EXW33_RS22365	COG1253	flavin adenine dinucleotide binding
EXW33_RS22380	COG1114	Component of the transport system for branched-chain amino acids
EXW33_RS22385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW33_RS22405	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW33_RS22415	COG1876	peptidase activity
EXW33_RS22430	COG2211	Major facilitator Superfamily
EXW33_RS22445	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW33_RS22455	COG0561	phosphatase activity
EXW33_RS22460	COG1846	Transcriptional regulator
EXW33_RS22465	COG2814	Major facilitator Superfamily
EXW33_RS22475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW33_RS22490	COG1819	glycosyl
EXW33_RS22495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW33_RS22500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW33_RS22525	COG0456	acetyltransferase
EXW33_RS22630	COG3874	Sporulation protein YtfJ
EXW33_RS22655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW33_RS22675	COG0346	lactoylglutathione lyase activity
EXW33_RS22690	COG1595	DNA-templated transcription, initiation
EXW33_RS22710	COG0426	domain, Protein
EXW33_RS22710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW33_RS22720	COG0386	Belongs to the glutathione peroxidase family
EXW33_RS22725	COG1305	Transglutaminase-like
EXW33_RS22730	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW33_RS22735	COG0714	Associated with various cellular activities
EXW33_RS22740	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW33_RS22745	COG1140	nitrate reductase beta subunit
EXW33_RS22750	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW33_RS22755	COG2181	nitrate reductase activity
EXW33_RS22760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW33_RS22765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW33_RS22770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW33_RS22775	COG0303	'Molybdopterin
EXW33_RS22780	COG0314	molybdopterin synthase activity
EXW33_RS22790	COG2223	nitrite transmembrane transporter activity
EXW33_RS22810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW33_RS22810	COG1587	Uroporphyrinogen-III synthase
EXW33_RS22815	COG2146	nitrite reductase [NAD(P)H] activity
EXW33_RS22820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW33_RS22825	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW33_RS22860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW33_RS22905	COG2359	stage V sporulation protein S
EXW33_RS22915	COG1418	mRNA catabolic process
EXW33_RS22920	COG0488	(ABC) transporter
EXW33_RS22965	COG0210	DNA helicase
EXW33_RS22990	COG0629	single-stranded DNA binding
EXW33_RS23000	COG1413	lyase activity
EXW33_RS23015	COG2136	Putative SAM-dependent methyltransferase
EXW33_RS23015	COG2521	methyltransferase
EXW33_RS23020	COG0018	arginyl-trna synthetase
EXW33_RS23050	COG0017	Asparaginyl-tRNA synthetase
EXW33_RS23055	COG0733	neurotransmitter:sodium symporter activity
EXW33_RS23080	COG2610	gluconate transmembrane transporter activity
EXW33_RS23090	COG1794	racemase activity, acting on amino acids and derivatives
EXW33_RS23100	COG0456	acetyltransferase
EXW33_RS23105	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW33_RS23120	COG0546	phosphoglycolate phosphatase activity
EXW33_RS23135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW33_RS23150	COG0768	penicillin binding
EXW33_RS23160	COG0204	Acyl-transferase
EXW33_RS23165	COG1272	protein, Hemolysin III
EXW33_RS23175	COG0805	protein transport
EXW33_RS23185	COG1307	EDD domain protein, DegV family
EXW33_RS23190	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW33_RS23195	COG1999	signal sequence binding
EXW33_RS23200	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW33_RS23205	COG0367	asparagine synthase
EXW33_RS23220	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW33_RS23225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW33_RS23230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW33_RS23245	COG1335	isochorismatase
EXW33_RS23250	COG1051	belongs to the nudix hydrolase family
EXW33_RS23255	COG0668	transmembrane transport
EXW33_RS23260	COG4585	Histidine kinase
EXW33_RS23260	COG2203	Gaf domain
EXW33_RS23265	COG2197	response regulator
EXW33_RS23270	COG1737	Transcriptional regulator
EXW33_RS23275	COG1064	alcohol dehydrogenase
EXW33_RS23300	COG1070	Carbohydrate kinase
EXW33_RS23310	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW33_RS23345	COG0517	IMP dehydrogenase activity
EXW33_RS23345	COG1125	glycine betaine transport
EXW33_RS23350	COG1174	glycine betaine transport
EXW33_RS23385	COG1253	flavin adenine dinucleotide binding
EXW33_RS23390	COG1012	belongs to the aldehyde dehydrogenase family
EXW33_RS23395	COG5506	Protein of unknown function (DUF1694)
EXW33_RS23410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW33_RS23415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW33_RS23420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW33_RS23425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW33_RS23430	COG0456	acetyltransferase
EXW33_RS23435	COG3829	transcription factor binding
EXW33_RS23440	COG1509	lysine 2,3-aminomutase activity
EXW33_RS23475	COG3064	Membrane
EXW33_RS23475	COG0515	serine threonine protein kinase
EXW33_RS23475	COG4991	sh3 domain protein
EXW33_RS23485	COG0671	phosphoesterase, PA-phosphatase related
EXW33_RS23490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW33_RS23495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW33_RS23540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW33_RS23565	COG1028	Short-chain dehydrogenase reductase Sdr
EXW33_RS23585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW33_RS23585	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW33_RS23595	COG2814	Major facilitator Superfamily
EXW33_RS23605	COG0372	Belongs to the citrate synthase family
EXW33_RS23610	COG2079	MmgE PrpD family protein
EXW33_RS23615	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW33_RS23620	COG1960	acyl-CoA dehydrogenase activity
EXW33_RS23625	COG2084	Dehydrogenase
EXW33_RS23635	COG1280	lysine exporter protein (LysE YggA)
EXW33_RS23640	COG1024	Enoyl-CoA hydratase
EXW33_RS23655	COG0420	3'-5' exonuclease activity
EXW33_RS23685	COG2223	nitrite transmembrane transporter activity
EXW33_RS23690	COG1028	Short-chain dehydrogenase reductase Sdr
EXW33_RS23695	COG1169	isochorismate synthase
EXW33_RS23700	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW33_RS23705	COG3433	isochorismatase activity
EXW33_RS23705	COG1535	isochorismatase
EXW33_RS23710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW33_RS23715	COG3251	PFAM MbtH domain protein
EXW33_RS23720	COG2814	Major facilitator Superfamily
EXW33_RS23735	COG0776	regulation of translation
EXW33_RS23745	COG2318	DinB family
EXW33_RS23765	COG1115	amino acid carrier protein
EXW33_RS23780	COG2329	Antibiotic biosynthesis monooxygenase
EXW33_RS23785	COG1187	pseudouridine synthase activity
EXW33_RS23790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW33_RS23795	COG1136	(ABC) transporter
EXW33_RS23805	COG0596	Alpha beta hydrolase
EXW33_RS23820	COG0028	Belongs to the TPP enzyme family
EXW33_RS23855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW33_RS23865	COG2207	Transcriptional regulator
EXW33_RS23890	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW33_RS23890	COG2755	lipolytic protein G-D-S-L family
EXW33_RS23900	COG5002	protein histidine kinase activity
EXW33_RS23910	COG0745	RESPONSE REGULATOR receiver
EXW33_RS23930	COG1846	Transcriptional regulator
EXW33_RS23940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW33_RS23945	COG1309	transcriptional regulator
EXW33_RS23970	COG1247	-acetyltransferase
EXW33_RS23995	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW33_RS24005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW33_RS24035	COG0583	DNA-binding transcription factor activity
EXW33_RS24040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW33_RS24045	COG0583	DNA-binding transcription factor activity
EXW33_RS24050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW33_RS24055	COG2258	MOSC domain
EXW33_RS24070	COG1132	(ABC) transporter
EXW33_RS24075	COG1132	(ABC) transporter
EXW33_RS24090	COG1396	sequence-specific DNA binding
EXW33_RS24125	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW33_RS24130	COG1595	DNA-templated transcription, initiation
EXW33_RS24155	COG1649	PFAM Uncharacterised BCR, COG1649
EXW33_RS24175	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW33_RS24180	COG2971	BadF BadG BcrA BcrD
EXW33_RS24210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW33_RS24240	COG2226	methyltransferase
EXW33_RS24245	COG3961	Belongs to the TPP enzyme family
EXW33_RS24280	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW33_RS24310	COG2002	toxin-antitoxin pair type II binding
EXW33_RS24320	COG0730	response to heat
EXW33_RS24325	COG0110	maltose O-acetyltransferase activity
EXW33_RS24330	COG1686	Belongs to the peptidase S11 family
EXW33_RS24350	COG0768	penicillin binding
EXW33_RS24355	COG1595	DNA-templated transcription, initiation
EXW33_RS24365	COG0768	penicillin binding
EXW33_RS24370	COG0768	penicillin binding
EXW33_RS24415	COG0697	spore germination
EXW33_RS24425	COG3397	chitin binding
EXW33_RS24430	COG0823	Involved in the tonB-independent uptake of proteins
EXW33_RS24450	COG1131	(ABC) transporter
EXW33_RS24460	COG1309	transcriptional regulator
EXW33_RS24470	COG1960	acyl-CoA dehydrogenase activity
EXW33_RS24475	COG0439	Biotin carboxylase
EXW33_RS24480	COG0511	ligase activity, forming carbon-carbon bonds
EXW33_RS24485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW33_RS24490	COG1024	Enoyl-CoA hydratase
EXW33_RS24495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW33_RS24500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW33_RS24555	COG2318	DinB family
EXW33_RS24560	COG1686	Belongs to the peptidase S11 family
EXW33_RS24585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW33_RS24605	COG3227	Zinc metalloprotease (Elastase)
EXW33_RS24610	COG2207	Transcriptional regulator
EXW33_RS24640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW33_RS24655	COG1733	regulation of RNA biosynthetic process
EXW33_RS24660	COG2226	methyltransferase
EXW33_RS24670	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW33_RS24680	COG1942	4-Oxalocrotonate Tautomerase
EXW33_RS24685	COG0583	DNA-binding transcription factor activity
EXW33_RS24710	COG0697	spore germination
EXW33_RS24715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW33_RS24740	COG2323	membrane
EXW33_RS24750	COG0693	protein deglycase activity
EXW33_RS24760	COG3386	PFAM SMP-30 Gluconolaconase
EXW33_RS24770	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW33_RS24775	COG3773	Cell wall hydrolase
EXW33_RS24785	COG0745	RESPONSE REGULATOR receiver
EXW33_RS24790	COG2205	protein histidine kinase activity
EXW33_RS24800	COG0583	DNA-binding transcription factor activity
EXW33_RS24805	COG0667	Aldo Keto reductase
EXW33_RS24810	COG0488	(ABC) transporter
EXW33_RS24820	COG1136	(ABC) transporter
EXW33_RS24825	COG0577	efflux transmembrane transporter activity
EXW33_RS24850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW33_RS24860	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW33_RS25015	COG0582	viral genome integration into host DNA
EXW33_RS25025	COG1011	Hydrolase
EXW33_RS25045	COG1216	Glycosyl transferase, family 2
EXW33_RS25110	COG2124	cytochrome p450
EXW33_RS25145	COG0561	phosphatase activity
EXW33_RS25150	COG5002	protein histidine kinase activity
EXW33_RS25155	COG0768	penicillin binding
EXW33_RS25165	COG1819	glycosyl
EXW33_RS25170	COG1794	racemase activity, acting on amino acids and derivatives
EXW33_RS25195	COG2205	protein histidine kinase activity
EXW33_RS25205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW33_RS25210	COG0604	alcohol dehydrogenase
EXW33_RS25215	COG0671	phosphoesterase, PA-phosphatase related
EXW33_RS25220	COG0768	penicillin binding
EXW33_RS25280	COG2814	Major facilitator Superfamily
EXW33_RS25295	COG0584	glycerophosphoryl diester phosphodiesterase
EXW33_RS25315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW33_RS25320	COG0697	spore germination
EXW33_RS25350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW33_RS25355	COG2223	nitrite transmembrane transporter activity
EXW33_RS25365	COG2816	NAD+ diphosphatase activity
EXW33_RS25370	COG0592	DNA-directed DNA polymerase activity
EXW33_RS25395	COG3878	Protein conserved in bacteria
EXW33_RS25420	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW33_RS25460	COG0322	excinuclease ABC activity
EXW33_RS25485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW33_RS25510	COG1011	Hydrolase
EXW33_RS25515	COG0745	RESPONSE REGULATOR receiver
EXW33_RS25520	COG5002	protein histidine kinase activity
EXW33_RS25555	COG1136	(ABC) transporter
EXW33_RS25560	COG0577	efflux transmembrane transporter activity
EXW33_RS25570	COG1073	alpha beta
EXW33_RS25575	COG0657	acetylesterase activity
EXW33_RS25580	COG0076	glutamate decarboxylase activity
EXW33_RS25595	COG1523	belongs to the glycosyl hydrolase 13 family
EXW33_RS25600	COG3227	Zinc metalloprotease (Elastase)
EXW33_RS25605	COG0737	Belongs to the 5'-nucleotidase family
EXW33_RS25615	COG0201	protein transport
EXW33_RS25620	COG0697	spore germination
EXW33_RS25625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW33_RS25660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW33_RS25675	COG2959	enzyme of heme biosynthesis
EXW33_RS25715	COG1309	transcriptional regulator
EXW33_RS25725	COG3284	Transcriptional regulator
EXW33_RS25740	COG1349	DNA-binding transcription factor activity
EXW33_RS25760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW33_RS25765	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW33_RS25770	COG0022	dehydrogenase e1 component
EXW33_RS25775	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW33_RS25785	COG1028	Short-chain dehydrogenase reductase Sdr
EXW33_RS25815	COG4176	ABC-type proline glycine betaine transport system permease component
EXW33_RS25820	COG0517	IMP dehydrogenase activity
EXW33_RS25820	COG4175	Glycine betaine
EXW33_RS25850	COG2153	protein acetylation
EXW33_RS25865	COG3397	chitin binding
EXW33_RS25875	COG1819	glycosyl
EXW33_RS25895	COG2205	protein histidine kinase activity
EXW33_RS25900	COG2226	methyltransferase
EXW33_RS25900	COG2267	carboxylic ester hydrolase activity
EXW33_RS25905	COG2315	Protein conserved in bacteria
EXW33_RS25960	COG3973	AAA domain
EXW33_RS25970	COG0514	ATP-dependent DNA helicase (RecQ)
EXW33_RS26000	COG4637	Psort location Cytoplasmic, score
EXW33_RS26015	COG3397	chitin binding
EXW33_RS26020	COG2318	DinB family
EXW33_RS26035	COG1162	GTPase activity
EXW33_RS26040	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW33_RS26045	COG1115	amino acid carrier protein
EXW33_RS26050	COG1012	belongs to the aldehyde dehydrogenase family
EXW33_RS26055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW33_RS26060	COG3938	Belongs to the proline racemase family
EXW33_RS26065	COG3938	Belongs to the proline racemase family
EXW33_RS26070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW33_RS26120	COG1078	dGTPase activity
EXW33_RS26125	COG0586	Pfam SNARE associated Golgi protein
EXW33_RS26140	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW33_RS26145	COG4166	transmembrane transport
EXW33_RS26155	COG4948	Mandelate Racemase Muconate Lactonizing
EXW33_RS26205	COG2936	dipeptidyl-peptidase activity
EXW33_RS26210	COG3850	Histidine kinase
EXW33_RS26210	COG5002	protein histidine kinase activity
EXW33_RS26215	COG0745	RESPONSE REGULATOR receiver
EXW33_RS26240	COG1164	Oligoendopeptidase f
EXW33_RS26245	COG0456	acetyltransferase
EXW33_RS26250	COG1307	EDD domain protein, DegV family
EXW33_RS26290	COG2814	Major facilitator Superfamily
EXW33_RS26300	COG1664	Polymer-forming cytoskeletal
EXW33_RS26305	COG0789	Transcriptional regulator
EXW33_RS26310	COG4533	DNA binding
EXW33_RS26315	COG0477	Major facilitator Superfamily
EXW33_RS26315	COG2814	Major facilitator Superfamily
EXW33_RS26340	COG2261	transglycosylase associated protein
EXW33_RS26355	COG2226	methyltransferase
EXW33_RS26390	COG0436	Aminotransferase
EXW33_RS26395	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW33_RS26405	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW33_RS26420	COG1131	(ABC) transporter
EXW33_RS26465	COG0628	permease
EXW33_RS26475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW33_RS26480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW33_RS26485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW33_RS26515	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW33_RS26550	COG0697	spore germination
EXW33_RS26580	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW33_RS26585	COG0346	lactoylglutathione lyase activity
EXW33_RS26590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW33_RS26615	COG2814	Major facilitator Superfamily
EXW33_RS26620	COG0861	Integral membrane protein TerC family
EXW33_RS26625	COG1368	sulfuric ester hydrolase activity
EXW33_RS26630	COG0488	(ABC) transporter
EXW33_RS26635	COG1033	growth of symbiont in host cell
EXW33_RS26635	COG2409	Drug exporters of the RND superfamily
EXW33_RS26640	COG1309	transcriptional regulator
EXW33_RS26645	COG1051	belongs to the nudix hydrolase family
EXW33_RS26660	COG0287	Prephenate dehydrogenase
EXW33_RS26675	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW33_RS26675	COG1605	Chorismate mutase
EXW33_RS26720	COG1388	LysM domain
EXW33_RS26720	COG3584	3D domain protein
EXW33_RS26730	COG0346	lactoylglutathione lyase activity
EXW33_RS26735	COG0519	Catalyzes the synthesis of GMP from XMP
EXW33_RS26740	COG0431	NADPH-dependent FMN reductase
EXW33_RS26765	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW33_RS26770	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW33_RS26780	COG2390	Transcriptional regulator
EXW33_RS26785	COG1070	Carbohydrate kinase
EXW33_RS26815	COG2329	Antibiotic biosynthesis monooxygenase
EXW33_RS26835	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW33_RS26840	COG2207	Transcriptional regulator
EXW33_RS26845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW33_RS26850	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW33_RS26855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW33_RS26860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW33_RS26865	COG4187	Peptidase family M20/M25/M40
EXW33_RS26870	COG1414	Transcriptional regulator
EXW33_RS26875	COG0833	amino acid
EXW33_RS26890	COG3239	Fatty acid desaturase
EXW33_RS26900	COG1785	Belongs to the alkaline phosphatase family
EXW33_RS26910	COG3655	Transcriptional regulator
EXW33_RS26935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW33_RS26940	COG0346	lactoylglutathione lyase activity
EXW33_RS26960	COG0714	Associated with various cellular activities
EXW33_RS26990	COG0753	catalase activity
EXW33_RS27030	COG0714	Associated with various cellular activities
EXW33_RS27070	COG0778	Nitroreductase
EXW33_RS27075	COG1846	Transcriptional regulator
EXW33_RS27095	COG4884	unkown
EXW33_RS27095	COG3831	ATPase activity
EXW33_RS27130	COG0456	acetyltransferase
EXW33_RS27150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW33_RS27195	COG0730	response to heat
EXW33_RS27205	COG0833	amino acid
EXW33_RS27215	COG4335	DNA alkylation repair
EXW33_RS27245	COG0768	penicillin binding
EXW33_RS27275	COG1984	allophanate hydrolase subunit 2
EXW33_RS27280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW33_RS27285	COG1414	Transcriptional regulator
EXW33_RS27300	COG3142	Participates in the control of copper homeostasis
EXW33_RS27310	COG1960	acyl-CoA dehydrogenase activity
EXW33_RS27325	COG3314	Sporulation integral membrane protein YlbJ
EXW33_RS27355	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW33_RS27375	COG0574	Belongs to the PEP-utilizing enzyme family
EXW33_RS27375	COG3848	Pyruvate phosphate dikinase
EXW33_RS27390	COG3344	reverse transcriptase
EXW33_RS27420	COG1533	DNA photolyase activity
EXW33_RS27440	COG1090	epimerase
EXW33_RS27455	COG2155	Conserved Protein
EXW33_RS27465	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW33_RS27475	COG0415	Belongs to the DNA photolyase family
EXW33_RS27485	COG2814	Major facilitator Superfamily
EXW33_RS27495	COG0288	reversible hydration of carbon dioxide
EXW33_RS27500	COG0640	Transcriptional regulator
EXW33_RS27575	COG1329	Transcriptional regulator
EXW33_RS27585	COG0662	Cupin 2, conserved barrel domain protein
EXW33_RS27640	COG3118	belongs to the thioredoxin family
EXW33_RS27645	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW33_RS27655	COG0457	Tetratricopeptide repeat
EXW33_RS27665	COG4166	transmembrane transport
EXW33_RS27715	COG0706	membrane insertase activity
EXW33_RS27725	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EXW33_RS27745	COG1131	(ABC) transporter
EXW33_RS27895	COG1476	TRANSCRIPTIONal
EXW33_RS27940	COG1696	Membrane protein involved in D-alanine export
EXW33_RS27955	COG0745	RESPONSE REGULATOR receiver
EXW33_RS27980	COG2318	DinB family
EXW33_RS27985	COG2378	regulation of single-species biofilm formation
EXW33_RS27995	COG1329	Transcriptional regulator
EXW33_RS28030	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW33_RS28080	COG3711	transcriptional antiterminator
EXW33_RS28085	COG1263	PTS System
EXW33_RS28085	COG2190	(PTS) system
EXW33_RS28085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW33_RS28090	COG2723	6-phospho-beta-galactosidase activity
EXW33_RS28105	COG2312	Erythromycin esterase
EXW33_RS28190	COG1725	Transcriptional regulator
EXW33_RS28195	COG1131	(ABC) transporter
EXW33_RS28215	COG3338	carbonate dehydratase activity
EXW33_RS28225	COG5002	protein histidine kinase activity
EXW33_RS28255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW33_RS28315	COG0583	DNA-binding transcription factor activity
EXW33_RS28335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW33_RS28340	COG4974	Belongs to the 'phage' integrase family
EXW33_RS28345	COG4257	antibiotic catabolic process
EXW33_RS28360	COG0302	gtp cyclohydrolase
EXW33_RS28370	COG0720	synthase
EXW33_RS28390	COG4555	ABC transporter
EXW33_RS28400	COG2226	methyltransferase
EXW33_RS28510	COG0798	PFAM Bile acid sodium symporter
EXW33_RS28515	COG0346	lactoylglutathione lyase activity
EXW33_RS28520	COG0640	Transcriptional regulator
EXW33_RS28565	COG1136	(ABC) transporter
EXW33_RS28590	COG0745	RESPONSE REGULATOR receiver
EXW33_RS28605	COG0753	catalase activity
EXW33_RS28610	COG4565	transcriptional regulatory protein
EXW33_RS28615	COG3290	protein histidine kinase activity
EXW33_RS28645	COG0456	acetyltransferase
EXW33_RS28660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW33_RS28670	COG0010	Belongs to the arginase family
EXW33_RS28680	COG0662	Cupin 2, conserved barrel domain protein
EXW33_RS28685	COG1999	signal sequence binding
EXW33_RS28700	COG1131	(ABC) transporter
EXW33_RS28720	COG1957	nucleoside hydrolase
EXW33_RS28730	COG3227	Zinc metalloprotease (Elastase)
EXW33_RS28740	COG2226	methyltransferase
EXW33_RS28765	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW33_RS28775	COG2002	toxin-antitoxin pair type II binding
EXW33_RS28985	COG1475	DNA binding