locus-tag class description FOC76_RS00025 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FOC76_RS00050 ENOG410847I Transcriptional regulator, BadM Rrf2 family FOC76_RS00060 ENOG4105CMT Dihydroxyacetone kinase FOC76_RS00070 ENOG4105CMT Dihydroxyacetone kinase FOC76_RS00090 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC76_RS00155 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC76_RS00185 ENOG4105CDU Replicative dna helicase FOC76_RS00225 ENOG4105CFI type iii restriction protein res subunit FOC76_RS00240 ENOG4105M6F mutator MutT protein FOC76_RS00250 ENOG4108MRH transcriptional regulatory protein FOC76_RS00260 ENOG4105CSH Transporter FOC76_RS00290 ENOG4105CTU Proline racemase FOC76_RS00310 ENOG4105DER m42 family FOC76_RS00330 ENOG4105CGU Enoyl-CoA hydratase FOC76_RS00340 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FOC76_RS00350 ENOG4106AKK s-layer domain-containing protein FOC76_RS00380 ENOG4105CHH sulfate transporter FOC76_RS00405 ENOG4105D4P Coproporphyrinogen iii oxidase FOC76_RS00410 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC76_RS00430 ENOG4107FQX Alpha-acetolactate decarboxylase FOC76_RS00465 ENOG410839P FOC76_RS00480 ENOG4105CDA abc transporter atp-binding protein FOC76_RS00485 ENOG4105DRP amino acid AbC transporter FOC76_RS00495 ENOG4105BZ1 (ABC) transporter FOC76_RS00500 ENOG4105BZ1 (ABC) transporter FOC76_RS00505 ENOG4105C26 Dehydrogenase FOC76_RS00515 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FOC76_RS00520 ENOG4105D5Q Arginine ornithine antiporter FOC76_RS00530 ENOG4105CH6 catalase FOC76_RS00535 ENOG4107RKG DJ-1/PfpI family FOC76_RS00545 ENOG4105E5W Transporter FOC76_RS00585 ENOG4105KPY Small multidrug resistance protein FOC76_RS00600 ENOG4108YXU transcriptional regulator AsnC family FOC76_RS00640 ENOG4106KNT transcriptional regulator FOC76_RS00650 ENOG4107RWR Sodium hydrogen exchanger FOC76_RS00655 ENOG4105CUB amino acid FOC76_RS00690 ENOG4107T5V SNARE associated Golgi FOC76_RS00725 ENOG4105WEF catalase FOC76_RS00755 ENOG4105C19 ABC transporter FOC76_RS00760 ENOG4107RBB ABC transporter, permease FOC76_RS00780 ENOG4105YVS arsR family transcriptional regulator FOC76_RS00790 ENOG4107SET aldo keto reductase FOC76_RS00795 ENOG4105F27 Major Facilitator FOC76_RS00800 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase FOC76_RS00805 ENOG4107XZQ multidrug resistance protein FOC76_RS00815 ENOG4105C1B dTDP-glucose 4-6-dehydratase FOC76_RS00835 ENOG41069ER domain protein FOC76_RS00855 ENOG4105VZJ PTS System FOC76_RS00860 ENOG4105VCP PTS System FOC76_RS00865 ENOG4105EMD TRANSCRIPTIONal FOC76_RS00890 ENOG4108KGH TRANSCRIPTIONal FOC76_RS00900 ENOG41087NI Sulfite exporter TauE/SafE FOC76_RS00905 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase FOC76_RS00915 ENOG4105VFE sira family FOC76_RS00920 ENOG4105VFE sira family FOC76_RS00925 ENOG4107TPS domain protein FOC76_RS00930 ENOG4105VFE sira family FOC76_RS00935 ENOG4105XTG Pfam:DUF156 FOC76_RS00940 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase FOC76_RS00965 ENOG4105ED1 spovr family FOC76_RS00970 ENOG4107Y03 Nitroreductase FOC76_RS00990 ENOG4108B31 Spore germination protein FOC76_RS01025 ENOG4105C5Y PTS System FOC76_RS01045 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FOC76_RS01055 ENOG4105C7N Xanthine uracil vitamin C permease FOC76_RS01070 ENOG4108INS Transcriptional regulator FOC76_RS01120 ENOG4105DWF phosphomethylpyrimidine kinase FOC76_RS01125 ENOG4105D06 uba thif-type nad fad binding protein FOC76_RS01140 ENOG41080HI glycine oxidase FOC76_RS01145 ENOG4108VEU Thiamine monophosphate synthase FOC76_RS01155 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC76_RS01165 ENOG4105ETU transcriptional activator (TenA FOC76_RS01185 ENOG41080XQ Signal transduction protein with cbs domains FOC76_RS01315 ENOG4105E2Z phosphate ABC transporter (Permease FOC76_RS01320 ENOG4105C8U phosphate abc transporter FOC76_RS01325 ENOG4105CVA phosphate FOC76_RS01330 ENOG4105CE1 Ferrous iron transport protein b FOC76_RS01335 ENOG4105CE1 Ferrous iron transport protein b FOC76_RS01340 ENOG4105CE1 Ferrous iron transport protein b FOC76_RS01350 ENOG4108NHD germination protein FOC76_RS01365 ENOG4105E1V na solute symporter FOC76_RS01390 ENOG4105E2S oxidase) subunit II FOC76_RS01395 ENOG4105BZ9 Cytochrome C oxidase, subunit I FOC76_RS01420 ENOG4105MA6 gCN5-related N-acetyltransferase FOC76_RS01435 ENOG4105C7N Xanthine uracil vitamin C permease FOC76_RS01440 ENOG4105C85 amino acid FOC76_RS01460 ENOG4105DUX Transporter FOC76_RS01470 ENOG4107D63 FOC76_RS01475 ENOG4105VZ8 Transcriptional regulator FOC76_RS01480 ENOG41069ER domain protein FOC76_RS01485 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC76_RS01490 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FOC76_RS01550 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FOC76_RS01555 ENOG4105CNN ABC, transporter FOC76_RS01570 ENOG4108RVA ribokinase FOC76_RS01575 ENOG4105ETE Transcriptional regulator (LacI family FOC76_RS01580 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC76_RS01585 ENOG41067TZ transcriptional regulator, MarR family FOC76_RS01590 ENOG4105CXY transporter FOC76_RS01600 ENOG4108JQ7 (ABC) transporter FOC76_RS01605 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC76_RS01625 ENOG41068KF Universal stress protein FOC76_RS01630 ENOG4105CHH sulfate transporter FOC76_RS01640 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC76_RS01645 ENOG4105BZU Histidine kinase FOC76_RS01650 ENOG4105NAE bifunctional deaminase-reductase domain protein FOC76_RS01655 ENOG4105D29 Helix-turn-helix type 11 domain protein FOC76_RS01665 ENOG4105GFR rna polymerase sigma factor FOC76_RS01680 ENOG4108IQI permease FOC76_RS01685 ENOG4105DRP amino acid AbC transporter FOC76_RS01690 ENOG4105EAD ABC transporter FOC76_RS01695 ENOG4105CT1 (ABC) transporter FOC76_RS01700 ENOG4105CDA abc transporter atp-binding protein FOC76_RS01705 ENOG4105BZG amino acid carrier protein FOC76_RS01710 ENOG4105CRN Aminoglycoside phosphotransferase FOC76_RS01720 ENOG4105E1K spore germination protein FOC76_RS01735 ENOG4105CG3 alpha amylase, catalytic region FOC76_RS01740 ENOG4105C5Y PTS System FOC76_RS01745 ENOG4107414 GntR family transcriptional regulator FOC76_RS01750 ENOG4105D5Q Arginine ornithine antiporter FOC76_RS01755 ENOG4105BZU Histidine kinase FOC76_RS01770 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC76_RS01775 ENOG4105GMT ATPase associated with various cellular activities aaa_5 FOC76_RS01780 ENOG4107T89 von Willebrand factor, type A FOC76_RS01790 ENOG4105EXW epimerase dehydratase FOC76_RS01800 ENOG4105DMQ Methyltransferase FOC76_RS01805 ENOG4105E0A ABC, transporter FOC76_RS01810 ENOG4108IHU transport system permease protein FOC76_RS01815 ENOG4105DQ5 transport system permease protein FOC76_RS01820 ENOG4108MES Periplasmic binding protein FOC76_RS01825 ENOG4105DUX Transporter FOC76_RS01840 ENOG4105DAA L-lactate FOC76_RS01845 ENOG4108IJ0 Aspartate ammonia-lyase FOC76_RS01850 ENOG4105C37 (CBS) domain FOC76_RS01855 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FOC76_RS01860 ENOG4105D9N nucleoside FOC76_RS01865 ENOG4108KGH TRANSCRIPTIONal FOC76_RS01870 ENOG41073R8 VanW family FOC76_RS01905 ENOG4105DAP Nicotinate phosphoribosyltransferase FOC76_RS01910 ENOG4105C59 p-type ATPase FOC76_RS01920 ENOG4105CUB amino acid FOC76_RS01940 ENOG4108JB9 formate dehydrogenase FOC76_RS01945 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC76_RS01950 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC76_RS01955 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC76_RS01960 ENOG4105BZU Histidine kinase FOC76_RS01970 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC76_RS01975 ENOG4108UZ3 Transporter FOC76_RS01985 ENOG4105C6K Malic enzyme FOC76_RS01995 ENOG4108MRH transcriptional regulatory protein FOC76_RS02020 ENOG4105US7 Histidine kinase FOC76_RS02025 ENOG4108STX response regulator FOC76_RS02050 ENOG4105D4T Citrate transporter FOC76_RS02055 ENOG4108V9W transcriptional regulatory protein FOC76_RS02060 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FOC76_RS02070 ENOG4105DZ6 Band 7 protein FOC76_RS02085 ENOG4105C94 Transporter FOC76_RS02105 ENOG4105CYN Serine protein kinase FOC76_RS02110 ENOG4105BZU Histidine kinase FOC76_RS02115 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FOC76_RS02125 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FOC76_RS02140 ENOG4107ZQN disulfide bond FOC76_RS02145 ENOG4108JQC penicillin-binding protein 1A FOC76_RS02260 ENOG4105G5W regulator Fur family FOC76_RS02265 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC76_RS02285 ENOG4108IUW ABC transporter FOC76_RS02295 ENOG4105CBC glutamate synthase FOC76_RS02300 ENOG4107NBY Membrane FOC76_RS02305 ENOG4105BZ1 (ABC) transporter FOC76_RS02325 ENOG4106BXE FOC76_RS02330 ENOG4105CEN a g-specific adenine glycosylase FOC76_RS02335 ENOG41067AE Membrane-bound metal-dependent hydrolase FOC76_RS02365 ENOG4105ECP epimerase FOC76_RS02370 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) FOC76_RS02390 ENOG4105F1A Pyruvate formate-lyase FOC76_RS02410 ENOG4105C3I Nad-dependent epimerase dehydratase FOC76_RS02415 ENOG4107QQG Dehydrogenase FOC76_RS02420 ENOG4105CKK Glycosyl transferase, family 2 FOC76_RS02440 ENOG4108A04 Beta-lactamase FOC76_RS02480 ENOG4108IQI permease FOC76_RS02490 ENOG4108JUB Transcriptional regulator FOC76_RS02540 ENOG4105UPD Calcium Proton FOC76_RS02545 ENOG410606W general stress protein FOC76_RS02560 ENOG4107ZTW SNARE associated Golgi FOC76_RS02570 ENOG4105C3F Signal peptidase i FOC76_RS02580 ENOG4108IPJ Membrane FOC76_RS02585 ENOG4105C59 p-type ATPase FOC76_RS02590 ENOG4107U9T Pfam:Ribonuclease_BN FOC76_RS02600 ENOG4105KJF protein tyrosine phosphatase FOC76_RS02620 ENOG4108TTB tellurium resistance protein FOC76_RS02625 ENOG4107TS3 membrane protein, TerC FOC76_RS02630 ENOG4106FN3 tellurium resistance protein FOC76_RS02635 ENOG4106FN3 tellurium resistance protein FOC76_RS02640 ENOG4108N0M stress protein FOC76_RS02675 ENOG4105DEU major facilitator superfamily FOC76_RS02690 ENOG41062JF Transcriptional regulator FOC76_RS02720 ENOG4105C5H ABC transporter FOC76_RS02740 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC76_RS02755 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FOC76_RS02785 ENOG4105CI1 PTS System FOC76_RS02795 ENOG4105DNP FAD linked oxidase domain protein FOC76_RS02805 ENOG4108W63 CRP FNR family transcriptional regulator FOC76_RS02810 ENOG4105C5B carbamate kinase FOC76_RS02835 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC76_RS02845 ENOG4105EAB amino acid AbC transporter FOC76_RS02850 ENOG4105E5Q amino acid AbC transporter FOC76_RS02865 ENOG4105D2S major facilitator superfamily FOC76_RS02870 ENOG410756H nucleotidyltransferase FOC76_RS02890 ENOG4105BZU Histidine kinase FOC76_RS02910 ENOG4106UIA FOC76_RS02915 ENOG4106UIA FOC76_RS02935 ENOG4108V5C ABC transporter FOC76_RS02940 ENOG4105DQ5 transport system permease protein FOC76_RS02945 ENOG4105EHG Permease protein FOC76_RS02965 ENOG4105D3R alkyl hydroperoxide reductase FOC76_RS02985 ENOG4105DFD Na H antiporter FOC76_RS02995 ENOG4105DTQ mandelate racemase muconate lactonizing FOC76_RS03010 ENOG4108W15 Protein of unknown function (DUF1456) FOC76_RS03015 ENOG4105BZU Histidine kinase FOC76_RS03025 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FOC76_RS03030 ENOG4105D9N nucleoside FOC76_RS03050 ENOG4105KPY Small multidrug resistance protein FOC76_RS03055 ENOG4105C26 Dehydrogenase FOC76_RS03065 ENOG4108JPW Aminotransferase FOC76_RS03070 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FOC76_RS03075 ENOG4105CBD Diacylglycerol kinase FOC76_RS03095 ENOG4107I77 yiaA/B two helix domain FOC76_RS03100 ENOG410834F Transcriptional regulator FOC76_RS03120 ENOG4105D01 (LipO)protein FOC76_RS03125 ENOG4108UMI ABC transporter, permease FOC76_RS03135 ENOG4108W2Y isochorismatase FOC76_RS03165 ENOG4105C4R Atp-dependent dna helicase FOC76_RS03190 ENOG4105C12 Phosphoribosylglycinamide synthetase FOC76_RS03200 ENOG4108V3E phosphoribosylglycinamide formyltransferase FOC76_RS03225 ENOG4105VR9 phosphoribosylformylglycinamidine synthase FOC76_RS03235 ENOG4105C83 adenylosuccinate lyase FOC76_RS03240 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FOC76_RS03245 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FOC76_RS03270 ENOG4105SX7 Transporter FOC76_RS03295 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC76_RS03335 ENOG4107ZXU DSBA oxidoreductase FOC76_RS03360 ENOG4105BZU Histidine kinase FOC76_RS03370 ENOG4105C7N Xanthine uracil vitamin C permease FOC76_RS03390 ENOG4108TYN CAAX amino terminal protease family protein FOC76_RS03405 ENOG4105C5H ABC transporter FOC76_RS03415 ENOG410801F ribosomal-protein-alanine acetyltransferase FOC76_RS03420 ENOG41072GX Peptidase M22 Glycoprotease FOC76_RS03425 ENOG4105K8N protein family UPF0079, ATPase FOC76_RS03525 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) FOC76_RS03535 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC76_RS03540 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein FOC76_RS03565 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FOC76_RS03570 ENOG4105CPF Cell wall formation (By similarity) FOC76_RS03580 ENOG4105CUB amino acid FOC76_RS03590 ENOG4105ERH Fumarylacetoacetate hydrolase FOC76_RS03595 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase FOC76_RS03625 ENOG410667J hydrolase FOC76_RS03630 ENOG4108JQ7 (ABC) transporter FOC76_RS03635 ENOG4105C3U ABC transporter FOC76_RS03640 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC76_RS03650 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein FOC76_RS03665 ENOG4105C5H ABC transporter FOC76_RS03690 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) FOC76_RS03700 ENOG4108RE7 deoxyribonuclease FOC76_RS03710 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC76_RS03730 ENOG4105F6E Acyl-transferase FOC76_RS03760 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family FOC76_RS03765 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FOC76_RS03770 ENOG4105E0C molybdate abc transporter FOC76_RS03790 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC76_RS03795 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC76_RS03815 ENOG4108JQ7 (ABC) transporter FOC76_RS03820 ENOG4105C3U ABC transporter FOC76_RS03825 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC76_RS03830 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC76_RS03845 ENOG4105C2C drug resistance transporter, Bcr CflA FOC76_RS03860 ENOG4105IQ5 FAD linked oxidase domain protein FOC76_RS03875 ENOG4108PSK reductase FOC76_RS03900 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FOC76_RS03910 ENOG4105CMG Carbohydrate kinase FOC76_RS03920 ENOG4108VQT Alpha beta hydrolase fold protein FOC76_RS03930 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FOC76_RS03945 ENOG4107U5W ybbr family FOC76_RS03950 ENOG4105C8B TIGR00159 family FOC76_RS04030 ENOG4108NMV polysaccharide deacetylase FOC76_RS04045 ENOG4105D1F ATP-binding protein FOC76_RS04075 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FOC76_RS04120 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC76_RS04130 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOC76_RS04260 ENOG4105XPM ribosomal protein FOC76_RS04275 ENOG4107Y49 methyltransferase FOC76_RS04300 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FOC76_RS04315 ENOG4105QIV RNA polymerase FOC76_RS04320 ENOG4105M0M Tetracycline resistance protein FOC76_RS04325 ENOG4105C2N RNA methyltransferase TrmH family group 3 FOC76_RS04340 ENOG4105D7W serine acetyltransferase FOC76_RS04360 ENOG4105CTP PilT protein domain protein FOC76_RS04370 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FOC76_RS04385 ENOG4108Z0C Uvrb UvrC protein FOC76_RS04475 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FOC76_RS04485 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FOC76_RS04490 ENOG4105KRF dihydroneopterin aldolase FOC76_RS04495 ENOG4105EEI dihydropteroate synthase FOC76_RS04500 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 FOC76_RS04505 ENOG4105DDQ anthranilate synthase FOC76_RS04510 ENOG4105CRQ synthase (Component I) FOC76_RS04515 ENOG4105C6T cysteine synthase FOC76_RS04530 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FOC76_RS04535 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC76_RS04560 ENOG41060GV RNA binding s1 domain protein FOC76_RS04575 ENOG4105VYY sporulation protein yabp FOC76_RS04580 ENOG41082I2 s4 domain protein FOC76_RS04585 ENOG4108IY2 MazG family FOC76_RS04595 ENOG4108M14 stage v sporulation protein t FOC76_RS04600 ENOG4108JA2 transcriptioN-repair coupling factor FOC76_RS04630 ENOG4105KME endoribonuclease L-psp FOC76_RS04635 ENOG4105DFT pur operon repressor FOC76_RS04650 ENOG4105W42 Veg protein FOC76_RS04655 ENOG4105XFA sporulation peptidase YabG FOC76_RS04665 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) FOC76_RS04670 ENOG4105F8V Hydrolase, tatD family FOC76_RS04675 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FOC76_RS04680 ENOG4105KRN Transcriptional regulator, abrb family FOC76_RS04685 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FOC76_RS04695 ENOG41060K3 Methyltransferase FOC76_RS04705 ENOG4105MA4 psp1 domain protein FOC76_RS04710 ENOG4105FA2 dna polymerase iii FOC76_RS04720 ENOG4105CXN decarboxylase FOC76_RS04755 ENOG41067KS pro-sigma K processing FOC76_RS04775 ENOG4105C6E dna polymerase iii FOC76_RS04785 ENOG4108Z6B deaminase FOC76_RS04790 ENOG4105GTG Isochorismatase FOC76_RS04800 ENOG4105ZMH deoxynucleoside kinase FOC76_RS04835 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FOC76_RS04870 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC76_RS04885 ENOG410848D S4 domain protein YaaA FOC76_RS04890 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC76_RS04910 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC76_RS04940 ENOG4107QJE Chromosome Partitioning Protein FOC76_RS04945 ENOG4105FA0 parb-like partition protein FOC76_RS04950 ENOG4108ZDA Sporulation protein YyaC FOC76_RS04955 ENOG4105D8X mechanosensitive ion channel FOC76_RS04960 ENOG4105VDK protein, conserved in bacteria FOC76_RS04965 ENOG4105C3G gtp-binding protein FOC76_RS04975 ENOG4108UUM single-stranded DNA-binding protein FOC76_RS04985 ENOG4108XMW Membrane FOC76_RS04990 ENOG4105BZR domain protein FOC76_RS05000 ENOG4105CDU Replicative dna helicase FOC76_RS05030 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC76_RS05035 ENOG4105BZU Histidine kinase FOC76_RS05050 ENOG4105Q2H domain protein FOC76_RS05055 ENOG4105C0H protease FOC76_RS05075 ENOG4105DPN Oligoendopeptidase f FOC76_RS05090 ENOG4105C1J atp-dependent rna helicase FOC76_RS05100 ENOG4108UT2 hemolysin iii FOC76_RS05105 ENOG4105CMR udp-glucose 4-epimerase FOC76_RS05115 ENOG4105IW1 AmiS UreI transporter FOC76_RS05125 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC76_RS05140 ENOG4107RGD Major Facilitator superfamily FOC76_RS05145 ENOG4108HRK Histidine kinase FOC76_RS05150 ENOG4105DY9 regulatoR FOC76_RS05165 ENOG4106F5Q Membrane FOC76_RS05170 ENOG4105E0X reductase FOC76_RS05180 ENOG41067SE Tetr family transcriptional regulator FOC76_RS05185 ENOG4105CKK Glycosyl transferase, family 2 FOC76_RS05205 ENOG4105C5H ABC transporter FOC76_RS05210 ENOG4105JEU Glycosyl transferase, family 2 FOC76_RS05220 ENOG4108S4H thioesterase Superfamily protein FOC76_RS05230 ENOG4106YBV Methyl-accepting chemotaxis FOC76_RS05235 ENOG4105EN6 Membrane FOC76_RS05255 ENOG41079KZ Major Facilitator Superfamily FOC76_RS05260 ENOG4105DY9 regulatoR FOC76_RS05265 ENOG4105D22 carbon starvation protein FOC76_RS05270 ENOG4105VCD cytoplasmic protein FOC76_RS05275 ENOG4105BZU Histidine kinase FOC76_RS05280 ENOG4105DWF phosphomethylpyrimidine kinase FOC76_RS05285 ENOG4105BZU Histidine kinase FOC76_RS05290 ENOG4105WH1 Two component transcriptional regulator luxr family FOC76_RS05300 ENOG4108Y4K DNA-binding transcriptional activator FOC76_RS05325 ENOG4105D6E homoserine dehydrogenase FOC76_RS05340 ENOG41090WU lipolytic protein G-D-S-L family FOC76_RS05345 ENOG4105CJ1 ABC, transporter FOC76_RS05350 ENOG4108TU7 Inherit from COG: (ABC) transporter FOC76_RS05360 ENOG4105VCH membrane FOC76_RS05365 ENOG410667J hydrolase FOC76_RS05375 ENOG4107SVH Potassium channel protein FOC76_RS05395 ENOG4108VKI Cell wall hydrolase FOC76_RS05410 ENOG4108IJ2 phosphate acetyltransferase FOC76_RS05415 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) FOC76_RS05425 ENOG4108VCI transcription factor, rsfa family FOC76_RS05435 ENOG4105DQ5 transport system permease protein FOC76_RS05440 ENOG4105EHG Permease protein FOC76_RS05445 ENOG4105E0A ABC, transporter FOC76_RS05450 ENOG4108MES Periplasmic binding protein FOC76_RS05455 ENOG4105DCI Phosphohydrolase FOC76_RS05460 ENOG41069HH 4-oxalocrotonate tautomerase FOC76_RS05465 ENOG4108Z4T Peptidase M50 FOC76_RS05470 ENOG4108XFG YwhD family FOC76_RS05475 ENOG4105BZ4 penicillin-binding protein FOC76_RS05480 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC76_RS05485 ENOG4107SWG transcriptional regulator MERR family FOC76_RS05490 ENOG4105DXB Major Facilitator superfamily FOC76_RS05500 ENOG4105CYW agmatinase FOC76_RS05520 ENOG410684U Domain of unknown function (DUF1934) FOC76_RS05555 ENOG4105IIU Aminopeptidase FOC76_RS05560 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) FOC76_RS05565 ENOG4108M15 ABC transporter FOC76_RS05570 ENOG4105KCT ABC transporter FOC76_RS05575 ENOG4105BZU Histidine kinase FOC76_RS05600 ENOG4105BZU Histidine kinase FOC76_RS05615 ENOG4105DF6 Fe-S oxidoreductase FOC76_RS05625 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FOC76_RS05630 ENOG4105C1G acyl-Coa dehydrogenase FOC76_RS05635 ENOG4105C1G acyl-Coa dehydrogenase FOC76_RS05675 ENOG4105CBT Fructose-1,6-bisphosphatase FOC76_RS05680 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FOC76_RS05700 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FOC76_RS05705 ENOG4108ZXQ stage ii sporulation protein r FOC76_RS05715 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FOC76_RS05730 ENOG4107XC4 flavin reductase domain protein, FMN-binding FOC76_RS05735 ENOG4108VGI doxx family FOC76_RS05750 ENOG4108YZG isomerase FOC76_RS05780 ENOG41062M3 atp synthase FOC76_RS05785 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) FOC76_RS05835 ENOG4105BZU Histidine kinase FOC76_RS05840 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FOC76_RS05850 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FOC76_RS05855 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOC76_RS05880 ENOG4105D65 subunit l FOC76_RS05885 ENOG4105C8S subunit m FOC76_RS05890 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOC76_RS05895 ENOG4106778 Protein of unknown function (DUF1146) FOC76_RS05915 ENOG4105DY9 regulatoR FOC76_RS05930 ENOG4105FRN stage II sporulation protein FOC76_RS05940 ENOG4105MT0 Sporulation transcriptional regulator spoiiid FOC76_RS05950 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase FOC76_RS05955 ENOG4107RZX Teichoic acid biosynthesis protein FOC76_RS05960 ENOG4107SJB teichoic acid biosynthesis FOC76_RS05965 ENOG4105CG5 Glycosyl transferase (Group 1 FOC76_RS05975 ENOG4107SJB teichoic acid biosynthesis FOC76_RS05985 ENOG4105EY8 ABC transporter FOC76_RS05990 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOC76_RS06010 ENOG4108RB3 Capsular polysaccharide biosynthesis protein FOC76_RS06015 ENOG4105CMR udp-glucose 4-epimerase FOC76_RS06020 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC76_RS06025 ENOG4105BZU Histidine kinase FOC76_RS06040 ENOG4105CXY transporter FOC76_RS06050 ENOG4105C19 ABC transporter FOC76_RS06055 ENOG4107RBB ABC transporter, permease FOC76_RS06095 ENOG4105C0D helicase FOC76_RS06100 ENOG4105KBK Zinc finger, swim domain protein FOC76_RS06125 ENOG41069ER domain protein FOC76_RS06130 ENOG4105C94 Transporter FOC76_RS06135 ENOG4107R8N Glycosyl transferase, family 2 FOC76_RS06160 ENOG4105E0M Sulfatase FOC76_RS06170 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) FOC76_RS06180 ENOG4105DAA L-lactate FOC76_RS06215 ENOG4107RSM transcriptional regulator FOC76_RS06220 ENOG4105ECB domain protein FOC76_RS06225 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase FOC76_RS06240 ENOG4105VZJ PTS System FOC76_RS06250 ENOG4105VCP PTS System FOC76_RS06260 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) FOC76_RS06270 ENOG4105CK1 PTS System FOC76_RS06275 ENOG4105VCP PTS System FOC76_RS06280 ENOG4105F8D glycoside hydrolase family 4 FOC76_RS06300 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FOC76_RS06310 ENOG4105ESV Glycosyl transferase, family 4 FOC76_RS06315 ENOG4105C6Y Udp-glucose 6-dehydrogenase FOC76_RS06320 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FOC76_RS06325 ENOG4108KGH TRANSCRIPTIONal FOC76_RS06330 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FOC76_RS06340 ENOG4105KVH Transcriptional regulator FOC76_RS06355 ENOG41081UC Inherit from COG: Competence protein FOC76_RS06360 ENOG4105VEQ Cold shock protein FOC76_RS06365 ENOG4105MS2 ribosomal subunit Interface protein FOC76_RS06385 ENOG4105CAK Cell division ATP-binding protein ftsE FOC76_RS06390 ENOG4105CRP Part of the ABC transporter FtsEX involved in FOC76_RS06395 ENOG4105CN1 protease FOC76_RS06405 ENOG4105BZ1 (ABC) transporter FOC76_RS06420 ENOG4108WS4 fmn reductase FOC76_RS06430 ENOG4105DUM transcriptional regulator, lysR family FOC76_RS06435 ENOG4105HMI Membrane FOC76_RS06460 ENOG4107TXC Transcriptional regulator FOC76_RS06475 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FOC76_RS06480 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOC76_RS06490 ENOG41086DT Membrane protein of unknown function FOC76_RS06510 ENOG4108S4C acetyltransferase FOC76_RS06520 ENOG4105C3M thioredoxin reductase FOC76_RS06530 ENOG4108Z4K mutator MutT protein FOC76_RS06540 ENOG4105CHW UPF0052 protein FOC76_RS06550 ENOG4105KRI phosphocarrier protein (HPr FOC76_RS06560 ENOG4108QY0 Membrane FOC76_RS06575 ENOG4105CZ3 stage V sporulation protein ad FOC76_RS06580 ENOG41090VF Stage v sporulation protein ac FOC76_RS06600 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC76_RS06650 ENOG41067MG lrgb family FOC76_RS06655 ENOG4105XZU Preprotein translocase, subunit SecG FOC76_RS06665 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FOC76_RS06685 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC76_RS06700 ENOG4105CM4 permease protein FOC76_RS06705 ENOG4108IPW abc transporter atp-binding protein FOC76_RS06715 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC76_RS06720 ENOG4105C5H ABC transporter FOC76_RS06745 ENOG4105WMR Protein CrcB homolog FOC76_RS06755 ENOG4105C8Q Methyl-accepting chemotaxis FOC76_RS06770 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FOC76_RS06785 ENOG4105KVH Transcriptional regulator FOC76_RS06790 ENOG4105F27 Major Facilitator FOC76_RS06795 ENOG4105CV8 reductase FOC76_RS06810 ENOG4108RYK Nad-dependent epimerase dehydratase FOC76_RS06825 ENOG4105D9N nucleoside FOC76_RS06830 ENOG4105D9N nucleoside FOC76_RS06850 ENOG4108URH decarboxylase FOC76_RS06870 ENOG4108RMU ferritin dps family protein FOC76_RS06880 ENOG4105NCW Trka-c domain protein FOC76_RS06885 ENOG4107S91 Sodium hydrogen exchanger FOC76_RS06890 ENOG4107T5V SNARE associated Golgi FOC76_RS06910 ENOG4105D4Y metalloprotease FOC76_RS06915 ENOG4105VG1 fes assembly suf system protein FOC76_RS06920 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC76_RS06925 ENOG4105C8Q Methyl-accepting chemotaxis FOC76_RS06945 ENOG4105BZU Histidine kinase FOC76_RS06950 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC76_RS06955 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FOC76_RS06965 ENOG4107ZTW SNARE associated Golgi FOC76_RS07000 ENOG4107AYK membrAne FOC76_RS07010 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC76_RS07025 ENOG4107R7I amino acid FOC76_RS07030 ENOG4108SUT Major Facilitator Superfamily FOC76_RS07050 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC76_RS07070 ENOG4105DZ1 carboxypeptidase FOC76_RS07085 ENOG4105CHU acetyl-coa acetyltransferase FOC76_RS07095 ENOG4105C1G acyl-Coa dehydrogenase FOC76_RS07100 ENOG4108W8B Beta-lactamase domain protein FOC76_RS07175 ENOG41080E8 Transcriptional regulator, Spx MgsR family FOC76_RS07210 ENOG4108UMI ABC transporter, permease FOC76_RS07215 ENOG4105D01 (LipO)protein FOC76_RS07220 ENOG4105D01 (LipO)protein FOC76_RS07225 ENOG4105C3K feS assembly ATPase SufC FOC76_RS07230 ENOG4105JRK feS assembly protein SufD FOC76_RS07235 ENOG4105C9B Cysteine desulfurase FOC76_RS07240 ENOG4108UNV SUF system FeS assembly protein, NifU family FOC76_RS07245 ENOG4105DIW FeS assembly protein SUFB FOC76_RS07260 ENOG4107R8B 5'-nucleotidase FOC76_RS07265 ENOG4105KZD Domain of unknown function (DUF1805) FOC76_RS07275 ENOG4105FAA peptidase M23 FOC76_RS07300 ENOG41090T1 Membrane FOC76_RS07305 ENOG4107TXC Transcriptional regulator FOC76_RS07310 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FOC76_RS07315 ENOG4105MMD transcriptional regulator FOC76_RS07330 ENOG4105CBT Fructose-1,6-bisphosphatase FOC76_RS07345 ENOG4105D4U had-superfamily hydrolase, subfamily iia FOC76_RS07355 ENOG4105DYS nad(p)h dehydrogenase (quinone) FOC76_RS07365 ENOG4108W5N phosphatidylglycerophosphatase a FOC76_RS07380 ENOG41083MR nifu domain-containing protein FOC76_RS07400 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FOC76_RS07405 ENOG4105C4B ABC transporter, permease FOC76_RS07410 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FOC76_RS07435 ENOG4108YX9 iron--sulfur cluster insertion protein erpA FOC76_RS07450 ENOG4105EWC Purine nucleoside phosphorylase FOC76_RS07475 ENOG4105CEP NADH dehydrogenase FOC76_RS07490 ENOG41069ER domain protein FOC76_RS07510 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOC76_RS07525 ENOG4105KA0 thioesterase Superfamily protein FOC76_RS07545 ENOG4107R3E Citrate transporter FOC76_RS07555 ENOG4105Y38 Kinase-associated protein B FOC76_RS07570 ENOG4105C87 Aminotransferase class I and II FOC76_RS07580 ENOG4108MUZ hydrolase FOC76_RS07585 ENOG4105C5I Dehydrogenase FOC76_RS07590 ENOG4108ZB6 transcriptional regulator AsnC family FOC76_RS07595 ENOG4105CHM Aminotransferase FOC76_RS07605 ENOG4105WG9 Conserved Protein FOC76_RS07620 ENOG4107PBV potassium channel FOC76_RS07625 ENOG4105KT7 mgtC SapB transporter FOC76_RS07660 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FOC76_RS07755 ENOG4105EMN RNA polymerase sigma factor FOC76_RS07770 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FOC76_RS07820 ENOG4105VEQ Cold shock protein FOC76_RS07830 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC76_RS07835 ENOG4105E4F Isochorismate synthase FOC76_RS07845 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) FOC76_RS07850 ENOG4108IPT Naphthoate synthase FOC76_RS07860 ENOG4105DTQ mandelate racemase muconate lactonizing FOC76_RS07880 ENOG41069H0 dihydroorotase EC 3.5.2.3 FOC76_RS07905 ENOG4105C6Z Gluconate FOC76_RS07945 ENOG41082BM Transcriptional regulator, arsr family FOC76_RS07955 ENOG41086D8 Transcriptional regulator FOC76_RS07960 ENOG4105C19 ABC transporter FOC76_RS07975 ENOG41063TF transcriptional regulator (AraC FOC76_RS07980 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) FOC76_RS07985 ENOG4107ZTW SNARE associated Golgi FOC76_RS08025 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) FOC76_RS08030 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC76_RS08055 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC76_RS08060 ENOG4105BZU Histidine kinase FOC76_RS08065 ENOG4105N67 Proton-coupled thiamine transporter YuaJ FOC76_RS08095 ENOG4108IBT Inherit from COG: transposase FOC76_RS08110 ENOG41087YS Phage shock protein A FOC76_RS08160 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC76_RS08165 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC76_RS08170 ENOG4108V2W Carbonate dehydratase FOC76_RS08225 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component FOC76_RS08235 ENOG4105D2X ABC transporter substrate-binding protein FOC76_RS08250 ENOG4107T7U Sulfatase FOC76_RS08255 ENOG4107S9D Alpha beta hydrolase FOC76_RS08265 ENOG4105BZU Histidine kinase FOC76_RS08335 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC76_RS08345 ENOG4108RIR Molybdenum cofactor biosynthesis protein FOC76_RS08355 ENOG4105BZF Glycosyl transferase (Group 1 FOC76_RS08360 ENOG4105YVM Phosphoesterase, PA-phosphatase related FOC76_RS08365 ENOG4108Z0R Transferase FOC76_RS08370 ENOG4105E8V Alpha Beta Hydrolase Fold protein FOC76_RS08405 ENOG4105CIG ABC transporter FOC76_RS08415 ENOG4105N5T Radical SAM Protein FOC76_RS08435 ENOG4105C19 ABC transporter FOC76_RS08450 ENOG4105NCW Trka-c domain protein FOC76_RS08455 ENOG4107S91 Sodium hydrogen exchanger FOC76_RS08460 ENOG410605W Major Facilitator FOC76_RS08490 ENOG4108B31 Spore germination protein FOC76_RS08500 ENOG4105DWV Homoserine O-trans-acetylase FOC76_RS08510 ENOG41085GJ domain protein FOC76_RS08530 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC76_RS08535 ENOG4105D06 uba thif-type nad fad binding protein FOC76_RS08545 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC76_RS08550 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein FOC76_RS08555 ENOG4108ZAF Molybdopterin FOC76_RS08575 ENOG4107EXU Short-chain dehydrogenase reductase Sdr FOC76_RS08580 ENOG4108VJ1 Transcriptional regulator (CarD family FOC76_RS08615 ENOG4105CBX hi0933 family FOC76_RS08630 ENOG4105YW5 deoR family transcriptional regulator FOC76_RS08635 ENOG4107QSE Dipeptidase FOC76_RS08645 ENOG4108IUM Glycogen debranching enzyme FOC76_RS08650 ENOG4108V15 phosphotransferase enzyme family FOC76_RS08665 ENOG4105C8F Beta-lactamase domain protein FOC76_RS08695 ENOG4108VDD TRNA binding domain protein FOC76_RS08705 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FOC76_RS08730 ENOG4105K7K Transcriptional regulator FOC76_RS08740 ENOG4108IPJ Membrane FOC76_RS08770 ENOG4105C88 aminopeptidase FOC76_RS08790 ENOG4105ETE Transcriptional regulator (LacI family FOC76_RS08820 ENOG4105EP9 oxidoreductase FOC76_RS08825 ENOG4107SNB ankyrin repeat protein YahD FOC76_RS08835 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC76_RS08850 ENOG4105DGU Histone deacetylase FOC76_RS08855 ENOG4105W87 Cbs domain FOC76_RS08860 ENOG4105F1V Acetoin utilization protein FOC76_RS08875 ENOG4105EMN RNA polymerase sigma factor FOC76_RS08905 ENOG4105C28 cystathionine FOC76_RS08915 ENOG4105U5Y Transcriptional regulator FOC76_RS08925 ENOG4105C5Q Transcriptional regulator FOC76_RS08950 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC76_RS08960 ENOG4105EFZ amidohydrolase FOC76_RS08975 ENOG4105KBJ sporulation protein ytfj FOC76_RS08980 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FOC76_RS09010 ENOG4108JYZ YitT family FOC76_RS09045 ENOG4107YZX Universal stress protein FOC76_RS09065 ENOG4105VZ8 Transcriptional regulator FOC76_RS09075 ENOG41082W1 Cupin 2, conserved barrel domain protein FOC76_RS09080 ENOG4105Z7P Acetyltransferase (GNAT) family FOC76_RS09120 ENOG4105DC7 peptidase M24 FOC76_RS09160 ENOG4105SFS phosphoesterase RecJ domain protein FOC76_RS09170 ENOG4105VV2 FOC76_RS09175 ENOG4105C0B DNA polymerase III (alpha subunit) FOC76_RS09180 ENOG4105C6K Malic enzyme FOC76_RS09185 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC76_RS09210 ENOG4105FS0 cytoplasmic membrane protein FOC76_RS09215 ENOG4108REF Sporulation integral membrane protein ytvi FOC76_RS09225 ENOG4105BZN citrate synthase FOC76_RS09230 ENOG4108HMX isocitrate dehydrogenase (NADP) FOC76_RS09250 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC76_RS09255 ENOG4105BZU Histidine kinase FOC76_RS09260 ENOG4105C2M dna polymerase I FOC76_RS09275 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FOC76_RS09280 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FOC76_RS09305 ENOG4108TDW sporulation protein YtxC FOC76_RS09310 ENOG4105C22 threonyL-tRNA synthetase FOC76_RS09335 ENOG4105CN9 Peptidase m42 family protein FOC76_RS09340 ENOG4108JGH Tetr family transcriptional regulator FOC76_RS09345 ENOG4105CW7 secretion protein, HlyD family FOC76_RS09350 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC76_RS09370 ENOG4108RWN rrna methyltransferase FOC76_RS09380 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) FOC76_RS09405 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FOC76_RS09420 ENOG4105DCG PHP domain protein FOC76_RS09430 ENOG4105FE9 pseudouridine synthase FOC76_RS09440 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) FOC76_RS09450 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) FOC76_RS09465 ENOG4105E0A ABC, transporter FOC76_RS09470 ENOG4105KFN sortase, SrtB family FOC76_RS09480 ENOG4105DR4 Methyltransferase FOC76_RS09495 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC76_RS09545 ENOG4105CEY Amp-dependent synthetase and ligase FOC76_RS09550 ENOG4107Z3H Transcriptional regulator, TetR family FOC76_RS09555 ENOG41060WC Enoyl-CoA hydratase FOC76_RS09560 ENOG4105BZJ Electron transfer flavoprotein FOC76_RS09565 ENOG4105C10 Electron transfer flavoprotein FOC76_RS09570 ENOG4105K63 Thioredoxin FOC76_RS09585 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit FOC76_RS09595 ENOG4105E33 succinate dehydrogenase FOC76_RS09605 ENOG4108VXD carboxy-peptidase FOC76_RS09610 ENOG4105E14 MotA TolQ exbB proton channel FOC76_RS09615 ENOG4105ER2 Ompa motb domain protein FOC76_RS09620 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family FOC76_RS09625 ENOG4108IUX (ABC) transporter FOC76_RS09630 ENOG4105RHA ABC transporter, permease FOC76_RS09635 ENOG4108Z40 Transcriptional regulator FOC76_RS09640 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FOC76_RS09650 ENOG4108JCI Transcriptional regulator FOC76_RS09655 ENOG41067S9 phage shock protein C, PspC FOC76_RS09660 ENOG4105DZC cytosine deaminase FOC76_RS09670 ENOG4105PFC Transcriptional regulator FOC76_RS09685 ENOG4105KBX Transcriptional regulator, TetR family FOC76_RS09695 ENOG4108PCX Major Facilitator FOC76_RS09705 ENOG4108XJQ germination protein FOC76_RS09720 ENOG4105M59 Phosphodiesterase, mj0936 family FOC76_RS09775 ENOG4108IUQ atp-dependent protease FOC76_RS09795 ENOG4105K56 Transcriptional regulator FOC76_RS09820 ENOG4105D52 delta-aminolevulinic acid dehydratase FOC76_RS09830 ENOG41068KH stage VI sporulation protein D FOC76_RS09845 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FOC76_RS09870 ENOG4105EKQ RNA-directed DNA polymerase FOC76_RS09880 ENOG4105DFF Rod shape-determining protein mreb FOC76_RS09900 ENOG4107QMS site-determining protein FOC76_RS09915 ENOG4105C03 ribonuclease FOC76_RS09925 ENOG4105X36 (ribosomal) protein FOC76_RS09940 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control FOC76_RS09950 ENOG4105EWM Histidine kinase FOC76_RS09970 ENOG4105CQC Prephenate dehydratase FOC76_RS09975 ENOG4108RPX mosc domain containing protein FOC76_RS09990 ENOG4108IYU L-aspartate oxidase FOC76_RS09995 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FOC76_RS10020 ENOG41082BM Transcriptional regulator, arsr family FOC76_RS10025 ENOG4108IPJ Membrane FOC76_RS10035 ENOG4108HUF Transporter FOC76_RS10050 ENOG41061AI Protein of unknown function (DUF2905) FOC76_RS10065 ENOG4105VIE preprotein translocase, subunit YajC FOC76_RS10075 ENOG4108QG2 Membrane FOC76_RS10080 ENOG4105CKP Polysaccharide Biosynthesis Protein FOC76_RS10090 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FOC76_RS10095 ENOG41076HS cation diffusion facilitator family transporter FOC76_RS10100 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FOC76_RS10110 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FOC76_RS10125 ENOG4105CUT histidyl-tRNA synthetase FOC76_RS10135 ENOG4105CUZ uba thif-type nad fad binding protein FOC76_RS10140 ENOG4108VCI transcription factor, rsfa family FOC76_RS10145 ENOG4105D1H recombination factor protein RarA FOC76_RS10155 ENOG4105C3J Cysteine desulfurase FOC76_RS10170 ENOG4105C7H Helicase, RecD TraA family FOC76_RS10175 ENOG41060CR FOC76_RS10190 ENOG4105C02 permease FOC76_RS10220 ENOG4105HHA aminodeoxychorismate lyase FOC76_RS10230 ENOG4105XYU peptidase (U32 family) FOC76_RS10235 ENOG4105CFP Peptidase U32 FOC76_RS10250 ENOG4107XRG penicillin-binding protein FOC76_RS10280 ENOG4105C28 cystathionine FOC76_RS10285 ENOG4105C0A alcohol dehydrogenase FOC76_RS10295 ENOG4108V5C ABC transporter FOC76_RS10300 ENOG4105S6R Iron-hydroxamate transporter permease subunit FOC76_RS10340 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FOC76_RS10350 ENOG4105MIR Phenylalanine 4-monooxygenase FOC76_RS10355 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FOC76_RS10390 ENOG4108MUZ hydrolase FOC76_RS10395 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FOC76_RS10400 ENOG4105G6Z alkaline phosphatase FOC76_RS10415 ENOG4108TVJ Nitroreductase FOC76_RS10435 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC76_RS10450 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase FOC76_RS10455 ENOG4105CQW ribosome biogenesis GTPase YqeH FOC76_RS10465 ENOG410812S Rna-binding protein FOC76_RS10475 ENOG4108WF2 Metal Dependent Phosphohydrolase FOC76_RS10485 ENOG4105DXX methyltransferase FOC76_RS10495 ENOG4105KQC Competence protein FOC76_RS10500 ENOG4108UK2 deaminase FOC76_RS10505 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FOC76_RS10515 ENOG4105TQK DNA polymerase iii, delta' subunit FOC76_RS10540 ENOG4105KVH Transcriptional regulator FOC76_RS10545 ENOG4105CSA Coproporphyrinogen iii oxidase FOC76_RS10575 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FOC76_RS10580 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FOC76_RS10590 ENOG4105KTH gatB Yqey FOC76_RS10595 ENOG41068P3 sporulation protein YqfC FOC76_RS10605 ENOG4105C9A Phoh family FOC76_RS10610 ENOG4105CTJ Metal Dependent Phosphohydrolase FOC76_RS10620 ENOG4107YR5 Diacylglycerol kinase FOC76_RS10625 ENOG4105KG3 cytidine deaminase FOC76_RS10630 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FOC76_RS10655 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FOC76_RS10660 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC76_RS10675 ENOG4105EGD dinuclear metal center protein, YbgI family FOC76_RS10700 ENOG41069ZM Protein of unknown function (DUF2624) FOC76_RS10705 ENOG4108JYZ YitT family FOC76_RS10710 ENOG4105FDK ABC transporter FOC76_RS10720 ENOG4105N80 Ferric uptake regulator, Fur family FOC76_RS10745 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC76_RS10755 ENOG4107RF6 penicillin-binding protein FOC76_RS10760 ENOG4105PWN phosphate abc transporter FOC76_RS10765 ENOG4105C8U phosphate abc transporter FOC76_RS10770 ENOG4105E2Z phosphate ABC transporter (Permease FOC76_RS10780 ENOG4108UTW Plays a role in the regulation of phosphate uptake FOC76_RS10795 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FOC76_RS10805 ENOG4105DKQ ROK family FOC76_RS10815 ENOG4105C5X domain protein FOC76_RS10835 ENOG4105C28 cystathionine FOC76_RS10840 ENOG4105C28 cystathionine FOC76_RS10850 ENOG4105C3R Methionine synthase FOC76_RS11035 ENOG4105C0D helicase FOC76_RS11065 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC76_RS11110 ENOG41080TC multidrug resistance protein FOC76_RS11135 ENOG4105WZW rhodanese family FOC76_RS11140 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) FOC76_RS11170 ENOG4107YBY Hydrolase FOC76_RS11180 ENOG4105CBJ Metal-dependent enzyme FOC76_RS11195 ENOG4105DC7 peptidase M24 FOC76_RS11220 ENOG4105CD2 stage iii sporulation protein aa FOC76_RS11225 ENOG4105KR5 Stage iii sporulation protein FOC76_RS11230 ENOG4108CQH stage III sporulation protein AC FOC76_RS11235 ENOG4105KQ4 Stage iii sporulation protein ad FOC76_RS11245 ENOG410644B Stage III sporulation protein af FOC76_RS11270 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC76_RS11275 ENOG4108ZSR alkaline shock protein FOC76_RS11300 ENOG4105CTB Polyprenyl synthetase FOC76_RS11310 ENOG4105DX0 Hemolysin A FOC76_RS11320 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FOC76_RS11325 ENOG4105S1Z Stage IV sporulation protein B FOC76_RS11330 ENOG4107QQR Sporulation FOC76_RS11340 ENOG41062GF Polar chromosome segregation protein FOC76_RS11435 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC76_RS11445 ENOG4108JUB Transcriptional regulator FOC76_RS11455 ENOG4107RDP Dehydrogenase FOC76_RS11460 ENOG4105CKM Branched-chain carboxylic acid kinase FOC76_RS11475 ENOG4105CPP Dehydrogenase, E1 component FOC76_RS11480 ENOG4105C7S Dehydrogenase FOC76_RS11490 ENOG4108QY0 Membrane FOC76_RS11500 ENOG4105G7B Protein of unknown function (DUF2992) FOC76_RS11510 ENOG4108HW3 (ABC) transporter FOC76_RS11515 ENOG4105E5Q amino acid AbC transporter FOC76_RS11520 ENOG4105CDA abc transporter atp-binding protein FOC76_RS11525 ENOG4108QEG Membrane FOC76_RS11530 ENOG4108VZI ErfK ybiS ycfS ynhG family protein FOC76_RS11545 ENOG4105D9U N-acetyltransferase FOC76_RS11550 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FOC76_RS11585 ENOG4105EJQ L-serine dehydratase FOC76_RS11590 ENOG4105II7 pyrroline-5-carboxylate reductase FOC76_RS11595 ENOG41069FQ Metallo-beta-lactamase superfamily FOC76_RS11600 ENOG4108IXY short-chain dehydrogenase reductase FOC76_RS11655 ENOG4105CGH 5'-nucleotidase FOC76_RS11660 ENOG4105DFD Na H antiporter FOC76_RS11670 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC76_RS11685 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC76_RS11690 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC76_RS11715 ENOG4108R6K riboflavin synthase, subunit alpha FOC76_RS11720 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FOC76_RS11740 ENOG4108YM7 Gcn5-related n-acetyltransferase FOC76_RS11745 ENOG4105ETE Transcriptional regulator (LacI family FOC76_RS11755 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FOC76_RS11775 ENOG4105RHY Pfam:UPF0157 FOC76_RS11785 ENOG4105CPC Aldo Keto reductase FOC76_RS11805 ENOG4105MZ9 stage II sporulation protein m FOC76_RS11810 ENOG4105I3K Ferric uptake regulator, Fur family FOC76_RS11820 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC76_RS11845 ENOG4105D7N magnesium and cobalt transport protein CorA FOC76_RS11880 ENOG4105DVE abc transporter atp-binding protein FOC76_RS11885 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC76_RS11890 ENOG4105DZ1 carboxypeptidase FOC76_RS11895 ENOG41082AN stage II sporulation protein FOC76_RS11905 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC76_RS11910 ENOG4105C8J )-transporter FOC76_RS11930 ENOG41090VF Stage v sporulation protein ac FOC76_RS11935 ENOG4105CZ3 stage V sporulation protein ad FOC76_RS11945 ENOG4105G6R Stage v sporulation protein ae FOC76_RS11955 ENOG4105J7I hydrolase FOC76_RS11960 ENOG4105PTM secreted protein FOC76_RS11965 ENOG4107ZE5 PPIases accelerate the folding of proteins FOC76_RS12000 ENOG4105CE4 GlcNAc 6-P deacetylase FOC76_RS12020 ENOG4105CID antiterminator FOC76_RS12035 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FOC76_RS12055 ENOG4105BZU Histidine kinase FOC76_RS12065 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOC76_RS12105 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FOC76_RS12125 ENOG4105DTD Dehydrogenase FOC76_RS12130 ENOG4105K7K Transcriptional regulator FOC76_RS12165 ENOG4105CHU acetyl-coa acetyltransferase FOC76_RS12170 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) FOC76_RS12210 ENOG4105CG3 alpha amylase, catalytic region FOC76_RS12220 ENOG4107FKK extracellular solute-binding protein family 1 FOC76_RS12230 ENOG4105EG2 ABC transporter, permease FOC76_RS12235 ENOG4105FKQ transcriptional regulator FOC76_RS12240 ENOG4105CHM Aminotransferase FOC76_RS12250 ENOG4108HGU Histidine kinase FOC76_RS12305 ENOG4105UIN FOC76_RS12315 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FOC76_RS12330 ENOG4105K6S Short-chain dehydrogenase reductase Sdr FOC76_RS12350 ENOG4107IN1 Protein of unknown function (DUF1797) FOC76_RS12360 ENOG4108XRC Protein of unknown function (DUF458) FOC76_RS12395 ENOG4107ZYR domain protein FOC76_RS12400 ENOG4105CN5 Metallo-Beta-Lactamase FOC76_RS12410 ENOG4108X4Q Hydrolase FOC76_RS12415 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FOC76_RS12430 ENOG4105CPP Dehydrogenase, E1 component FOC76_RS12480 ENOG4105CXN decarboxylase FOC76_RS12500 ENOG4105ECY inositol monophosphatase FOC76_RS12510 ENOG4105CI3 gtp-binding protein typa FOC76_RS12515 ENOG4105QA2 FOC76_RS12535 ENOG4108IAB Phoh family FOC76_RS12550 ENOG4105CNI cell division protein FtsW FOC76_RS12555 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) FOC76_RS12600 ENOG4106UY4 Inherit from COG: Scp-like extracellular FOC76_RS12615 ENOG4107TB6 phosphoglycerate mutase FOC76_RS12635 ENOG4106H78 methyltransferase FOC76_RS12645 ENOG4105H20 Sporulation integral membrane protein YlbJ FOC76_RS12650 ENOG4105D78 K07001 NTE family protein FOC76_RS12655 ENOG41063PX domain protein FOC76_RS12665 ENOG4105KNH Nucleic acid-binding protein FOC76_RS12700 ENOG41068DC Essential cell division protein (By similarity) FOC76_RS12705 ENOG4105CJN penicillin-binding protein FOC76_RS12710 ENOG4105CJN penicillin-binding protein FOC76_RS12715 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FOC76_RS12730 ENOG4105CNI cell division protein FtsW FOC76_RS12745 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) FOC76_RS12750 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FOC76_RS12755 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FOC76_RS12765 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC76_RS12775 ENOG4105WR5 sporulation protein, YlmC YmxH family FOC76_RS12780 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FOC76_RS12785 ENOG4105DFA alanine racemase domain protein FOC76_RS12795 ENOG41067XK integral membrane protein FOC76_RS12800 ENOG4105DBK s4 domain protein FOC76_RS12825 ENOG4105C34 Pseudouridine synthase FOC76_RS12910 ENOG4105DC7 peptidase M24 FOC76_RS12930 ENOG4105DSJ YicC domain protein FOC76_RS12950 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FOC76_RS12955 ENOG4105C25 Primosomal protein n' FOC76_RS12960 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FOC76_RS12970 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FOC76_RS12980 ENOG4108ZF3 Phosphatase FOC76_RS12985 ENOG4105D9P serine threonine protein kinase FOC76_RS12995 ENOG4105DJV ribulose-phosphate 3-epimerase FOC76_RS13000 ENOG4105FJ0 thiamine FOC76_RS13015 ENOG4108ZAA Alkaline-shock protein FOC76_RS13020 ENOG4105DP4 dak2 domain fusion protein ylov FOC76_RS13025 ENOG4105CB5 ATP-dependent DNA helicase recG FOC76_RS13040 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FOC76_RS13045 ENOG4105CHR reductase FOC76_RS13060 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FOC76_RS13065 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FOC76_RS13085 ENOG4105VB6 UPF0109 protein FOC76_RS13110 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) FOC76_RS13125 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FOC76_RS13130 ENOG4105C79 DNA protecting protein DprA FOC76_RS13135 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FOC76_RS13145 ENOG4108HE4 integrase family FOC76_RS13190 ENOG4105KNE Phosphatidate cytidylyltransferase FOC76_RS13200 ENOG4105DZP Membrane-associated zinc metalloprotease FOC76_RS13210 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC76_RS13220 ENOG4105CHV Transcription elongation factor NusA FOC76_RS13225 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination FOC76_RS13230 ENOG4105VHM ribosomal protein FOC76_RS13240 ENOG4105W7A Protein of unknown function (DUF503) FOC76_RS13255 ENOG4105DTN riboflavin biosynthesis protein ribF FOC76_RS13275 ENOG4105C1V Peptidase, M16 FOC76_RS13285 ENOG4105E35 Dipicolinate synthase subunit A FOC76_RS13290 ENOG4108S0H Dipicolinic acid synthetase, b subunit FOC76_RS13295 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC76_RS13305 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC76_RS13315 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit FOC76_RS13325 ENOG4107QZI cell division protein FtsK FOC76_RS13330 ENOG4105FDP GntR family transcriptional regulator FOC76_RS13335 ENOG4105DIH basic membrane FOC76_RS13340 ENOG4108JQ9 ABC transporter FOC76_RS13345 ENOG4105UIB (ABC) transporter FOC76_RS13365 ENOG4108RKS Short-chain dehydrogenase reductase Sdr FOC76_RS13370 ENOG4105XZV Protein of unknown function (DUF3243) FOC76_RS13385 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FOC76_RS13405 ENOG4105D48 metallophosphoesterase FOC76_RS13410 ENOG4105MCT stage V sporulation protein S FOC76_RS13415 ENOG4108IGT Dipeptidase FOC76_RS13420 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein FOC76_RS13425 ENOG4105DQU oxidoreductase, subunit beta FOC76_RS13455 ENOG4107QHE Choloylglycine hydrolase FOC76_RS13465 ENOG410890F Dynamin family FOC76_RS13470 ENOG4105E0M Sulfatase FOC76_RS13480 ENOG4105F0V Cell wall hydrolase FOC76_RS13515 ENOG41067MG lrgb family FOC76_RS13525 ENOG4107ZY0 Phenazine biosynthesis-like protein FOC76_RS13560 ENOG4105BZU Histidine kinase FOC76_RS13590 ENOG4105D03 DNA-3-methyladenine glycosylase II FOC76_RS13595 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC76_RS13605 ENOG4105CGK Exodeoxyribonuclease III FOC76_RS13625 ENOG4105E0A ABC, transporter FOC76_RS13630 ENOG4105NIV Esterase FOC76_RS13640 ENOG4105VPX protein, conserved in bacteria FOC76_RS13645 ENOG410681U heavy metal transport detoxification protein FOC76_RS13650 ENOG4105C59 p-type ATPase FOC76_RS13660 ENOG4105K70 DNA-binding protein FOC76_RS13665 ENOG4105TMB Formate nitrite transporter FOC76_RS13680 ENOG4105C85 amino acid FOC76_RS13690 ENOG4108SJC Membrane FOC76_RS13695 ENOG4107QW4 alcohol dehydrogenase FOC76_RS13700 ENOG4105E98 transcriptional regulator DeoR family FOC76_RS13705 ENOG4105DE4 1-phosphofructokinase FOC76_RS13710 ENOG4105DM4 PTS System FOC76_RS13715 ENOG41069ER domain protein FOC76_RS13745 ENOG4106F1P AAA ATPase, central domain protein FOC76_RS13750 ENOG4105EN6 Membrane FOC76_RS13755 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOC76_RS13760 ENOG4105CXI aluminum resistance protein FOC76_RS13765 ENOG4105KV4 Transcriptional regulator FOC76_RS13770 ENOG4105C5F glutamine synthetase FOC76_RS13800 ENOG4105K7K Transcriptional regulator FOC76_RS13820 ENOG4108SVB resolvase FOC76_RS13830 ENOG4105CGH 5'-nucleotidase FOC76_RS13835 ENOG4108HW3 (ABC) transporter FOC76_RS13870 ENOG4105BZ1 (ABC) transporter FOC76_RS13875 ENOG4105BZ1 (ABC) transporter FOC76_RS13890 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC76_RS13915 ENOG41067MG lrgb family FOC76_RS13925 ENOG4107RSM transcriptional regulator FOC76_RS13935 ENOG4105CJ1 ABC, transporter FOC76_RS13955 ENOG4107QIV Cytochrome c biogenesis protein FOC76_RS14020 ENOG4108903 Formimidoylglutamase FOC76_RS14025 ENOG4108VJ1 Transcriptional regulator (CarD family FOC76_RS14030 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FOC76_RS14035 ENOG4105CBC glutamate synthase FOC76_RS14045 ENOG4105CK7 Sodium proline symporter FOC76_RS14050 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase FOC76_RS14055 ENOG4105FBA Phospholipase Carboxylesterase FOC76_RS14060 ENOG4105BZU Histidine kinase FOC76_RS14070 ENOG4107AYK membrAne FOC76_RS14120 ENOG4108IMY Transcriptional regulator FOC76_RS14135 ENOG4105CEY Amp-dependent synthetase and ligase FOC76_RS14140 ENOG4107ZYJ bioY protein FOC76_RS14145 ENOG4107F3J Amp-dependent synthetase and ligase FOC76_RS14165 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC76_RS14175 ENOG4105E5W Transporter FOC76_RS14205 ENOG4108I0Z Aconitate hydratase FOC76_RS14210 ENOG4108JJA ABC, transporter FOC76_RS14220 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC76_RS14225 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC76_RS14250 ENOG4105D7V transposase FOC76_RS14260 ENOG4105W8X HesB YadR YfhF-family protein FOC76_RS14270 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase FOC76_RS14275 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) FOC76_RS14280 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC76_RS14285 ENOG4105C0H protease FOC76_RS14290 ENOG4105K4P CoA-binding domain protein FOC76_RS14295 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC76_RS14305 ENOG4105D9R oxidoreductase FOC76_RS14325 ENOG4105CIG ABC transporter FOC76_RS14340 ENOG4105EMN RNA polymerase sigma factor FOC76_RS14350 ENOG4108KGH TRANSCRIPTIONal FOC76_RS14355 ENOG4107QJT sodium dicarboxylate symporter FOC76_RS14410 ENOG4105CUB amino acid FOC76_RS14425 ENOG4105E1K spore germination protein FOC76_RS14430 ENOG4108JB9 formate dehydrogenase FOC76_RS14440 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) FOC76_RS14445 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC76_RS14455 ENOG4105TMB Formate nitrite transporter FOC76_RS14460 ENOG4105D06 uba thif-type nad fad binding protein FOC76_RS14465 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC76_RS14470 ENOG4108ZAF Molybdopterin FOC76_RS14480 ENOG4105D1F ATP-binding protein FOC76_RS14495 ENOG410696E Membrane FOC76_RS14500 ENOG4105FR1 rard protein FOC76_RS14510 ENOG4105EWU Squalene--hopene cyclase FOC76_RS14520 ENOG4105CHR reductase FOC76_RS14525 ENOG4105C26 Dehydrogenase FOC76_RS14535 ENOG4108IA2 Sodium pantothenate symporter FOC76_RS14550 ENOG4106IQC argininosuccinate lyase FOC76_RS14560 ENOG410904N short-chain dehydrogenase reductase FOC76_RS14580 ENOG4105M6F mutator MutT protein FOC76_RS14600 ENOG4105VEQ Cold shock protein FOC76_RS14620 ENOG4108R1P FOC76_RS14640 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FOC76_RS14655 ENOG4105KT7 mgtC SapB transporter FOC76_RS14665 ENOG4105BZU Histidine kinase FOC76_RS14690 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity FOC76_RS14695 ENOG41067SE Tetr family transcriptional regulator FOC76_RS14710 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) FOC76_RS14730 ENOG4105CQB FAD linked oxidase domain protein FOC76_RS14735 ENOG4105C09 Bile acid FOC76_RS14760 ENOG4105CIS alcohol dehydrogenase FOC76_RS14765 ENOG41082BM Transcriptional regulator, arsr family FOC76_RS14775 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC76_RS14805 ENOG4108A04 Beta-lactamase FOC76_RS14835 ENOG4105DPN Oligoendopeptidase f FOC76_RS14840 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FOC76_RS14845 ENOG4105E5K Alpha-amylase FOC76_RS14855 ENOG4105C98 muts2 protein FOC76_RS14870 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FOC76_RS14880 ENOG4107V2S Transcriptional regulator FOC76_RS14890 ENOG4107CUJ Protein of unknown function (DUF2690) FOC76_RS14895 ENOG41068WN FOC76_RS14915 ENOG4105NX3 Membrane FOC76_RS14920 ENOG4105DQ5 transport system permease protein FOC76_RS14925 ENOG4105EHG Permease protein FOC76_RS14930 ENOG4108MES Periplasmic binding protein FOC76_RS14945 ENOG4107R3E Citrate transporter FOC76_RS14955 ENOG4108TN2 lmbE family FOC76_RS14995 ENOG4105K7K Transcriptional regulator FOC76_RS15040 ENOG4105H3G oxidoreductase FOC76_RS15075 ENOG4107YXZ hydrolase, family 25 FOC76_RS15090 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) FOC76_RS15120 ENOG4105KAF membrAne FOC76_RS15140 ENOG410829K Lysine exporter protein (Lyse ygga) FOC76_RS15180 ENOG4105KVH Transcriptional regulator FOC76_RS15185 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein FOC76_RS15195 ENOG4105KNA -acetyltransferase FOC76_RS15205 ENOG4105CHR reductase FOC76_RS15215 ENOG4105JAB phenazine biosynthesis protein, phzf family FOC76_RS15250 ENOG4105D9R oxidoreductase FOC76_RS15255 ENOG4108TZY GntR Family Transcriptional Regulator FOC76_RS15280 ENOG4105C44 Serine transporter FOC76_RS15315 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FOC76_RS15330 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FOC76_RS15340 ENOG4105CMG Carbohydrate kinase FOC76_RS15345 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) FOC76_RS15350 ENOG4105XDF Protein of unknown function (DUF1272) FOC76_RS15355 ENOG4105DDN Pentapeptide repeat-containing protein FOC76_RS15380 ENOG4105FAW cDP-glucose 4,6-dehydratase FOC76_RS15385 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase FOC76_RS15400 ENOG4105C37 (CBS) domain FOC76_RS15430 ENOG4105EV4 Multidrug resistance protein mdtH FOC76_RS15440 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) FOC76_RS15480 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC76_RS15490 ENOG4108UW5 maltose o-acetyltransferase FOC76_RS15500 ENOG4105DKQ ROK family FOC76_RS15505 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase FOC76_RS15565 ENOG4105CJ1 ABC, transporter FOC76_RS15575 ENOG4108PSK reductase FOC76_RS15595 ENOG4108RCM Nitroreductase FOC76_RS15600 ENOG4105KVH Transcriptional regulator FOC76_RS15620 ENOG4108Z66 YbaK ebsC protein FOC76_RS15630 ENOG41067QW Transcriptional regulator FOC76_RS15645 ENOG4108K8S endonuclease I FOC76_RS15670 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FOC76_RS15710 ENOG4105CRW Short chain fatty acid transporter FOC76_RS15725 ENOG4105CZM Major Facilitator FOC76_RS15730 ENOG4107MII Sugar-specific transcriptional regulator TrmB FOC76_RS15745 ENOG4108ISG Major Facilitator FOC76_RS15755 ENOG4105PNM synthesis protein FOC76_RS15760 ENOG4108VXD carboxy-peptidase FOC76_RS15790 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC76_RS15805 ENOG410874W AraC family transcriptional regulator FOC76_RS15810 ENOG41082W1 Cupin 2, conserved barrel domain protein FOC76_RS15830 ENOG4108JQ1 Dehydrogenase FOC76_RS15845 ENOG4105DVH amino acid FOC76_RS15855 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) FOC76_RS15870 ENOG4108JPW Aminotransferase FOC76_RS15885 ENOG4105EJQ L-serine dehydratase FOC76_RS15890 ENOG4105C44 Serine transporter FOC76_RS15965 ENOG4105TRI Hydrolase FOC76_RS15990 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC76_RS16005 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC76_RS16015 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 FOC76_RS16020 ENOG4108U05 Transcriptional regulator FOC76_RS16035 ENOG4105BZU Histidine kinase FOC76_RS16050 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) FOC76_RS16070 ENOG4105JQZ Methyltransferase FOC76_RS16090 ENOG4105VZ8 Transcriptional regulator FOC76_RS16110 ENOG4105K6H D-cysteine desulfhydrase FOC76_RS16135 ENOG4108NIW Leucine export protein LeuE FOC76_RS16155 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC76_RS16160 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FOC76_RS16175 ENOG4105N0V mono-oxygenase ydhR FOC76_RS16225 ENOG4108YXU transcriptional regulator AsnC family FOC76_RS16230 ENOG4105CHR reductase FOC76_RS16235 ENOG4108IG5 Transcriptional regulator FOC76_RS16240 ENOG4107P5I polyketide synthase FOC76_RS16295 ENOG4105NAE bifunctional deaminase-reductase domain protein FOC76_RS16305 ENOG41085FC arsR family transcriptional regulator FOC76_RS16310 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC76_RS16315 ENOG4105D6J arsenicaL-resistance protein FOC76_RS16345 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC76_RS16360 ENOG4105GPN Uncharacterized conserved protein (DUF2294) FOC76_RS16365 ENOG4108TWJ NADH dehydrogenase subunit 5 FOC76_RS16380 ENOG4105F2M alpha beta hydrolase fold-3 domain protein FOC76_RS16400 ENOG4105CVP deoxyribo-dipyrimidine photolyase FOC76_RS16405 ENOG4108606 TspO/MBR family FOC76_RS16515 ENOG4105CHJ isochorismatase hydrolase FOC76_RS16525 ENOG4105CGH 5'-nucleotidase FOC76_RS16560 ENOG4105CSV Glutaminase FOC76_RS16580 ENOG4108Q8B Spore germination protein FOC76_RS16585 ENOG4108NHD germination protein FOC76_RS16590 ENOG4105II7 pyrroline-5-carboxylate reductase FOC76_RS16595 ENOG4105CUB amino acid FOC76_RS16600 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FOC76_RS16610 ENOG41075H3 AraC family transcriptional regulator FOC76_RS16635 ENOG4105BZU Histidine kinase FOC76_RS16645 ENOG4108B31 Spore germination protein FOC76_RS16670 ENOG4108IMY Transcriptional regulator FOC76_RS16675 ENOG4105HDK L-asparaginase FOC76_RS16680 ENOG4108IJ0 Aspartate ammonia-lyase FOC76_RS16690 ENOG4105E2A Dehydrogenase FOC76_RS16750 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FOC76_RS16780 ENOG4105DWD nucleoside recognition domain protein FOC76_RS16795 ENOG4105FDT acyl-CoA dehydrogenase FOC76_RS16805 ENOG4108ZHR arsR family transcriptional regulator FOC76_RS16810 ENOG4108ZRV stage ii sporulation protein p FOC76_RS16815 ENOG4106N3A copper homeostasis protein cutc FOC76_RS16825 ENOG4107258 Transcriptional regulator FOC76_RS16860 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FOC76_RS16870 ENOG4107RF6 penicillin-binding protein FOC76_RS16905 ENOG4105F1N DNA alkylation repair FOC76_RS16915 ENOG4108IQI permease FOC76_RS16925 ENOG410635A Membrane FOC76_RS16975 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) FOC76_RS17000 ENOG4108XET gCN5-related N-acetyltransferase FOC76_RS17005 ENOG4108DMH HTH_ARAC FOC76_RS17030 ENOG4105C19 ABC transporter FOC76_RS17040 ENOG4105WEC Molybdate metabolism regulator FOC76_RS17045 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FOC76_RS17065 ENOG4105FS7 Transcriptional regulator FOC76_RS17070 ENOG4108TVJ Nitroreductase FOC76_RS17090 ENOG4105CHH sulfate transporter FOC76_RS17095 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FOC76_RS17100 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC76_RS17140 ENOG4105C8Y Acetylornithine aminotransferase FOC76_RS17150 ENOG4105CKK Glycosyl transferase, family 2 FOC76_RS17165 ENOG4105CKK Glycosyl transferase, family 2 FOC76_RS17175 ENOG4105CSH Transporter FOC76_RS17190 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC76_RS17215 ENOG4105KNA -acetyltransferase FOC76_RS17230 ENOG4108NEV two component transcriptional regulator, LytTR family FOC76_RS17240 ENOG41090T1 Membrane FOC76_RS17255 ENOG4105VMP Transcriptional regulator FOC76_RS17265 ENOG4105G6Z alkaline phosphatase FOC76_RS17275 ENOG4105ECK Fatty Acid Desaturase FOC76_RS17280 ENOG4105E0Y RtcB Protein FOC76_RS17290 ENOG4107258 Transcriptional regulator FOC76_RS17300 ENOG4105II7 pyrroline-5-carboxylate reductase FOC76_RS17335 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) FOC76_RS17360 ENOG41061GT Aldolase FOC76_RS17370 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) FOC76_RS17375 ENOG4105DKT Transcriptional regulator FOC76_RS17385 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane FOC76_RS17390 ENOG4105F5R ABC transporter FOC76_RS17395 ENOG4105D4B ABC, transporter FOC76_RS17420 ENOG41069ER domain protein FOC76_RS17430 ENOG4105FFM Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein (By similarity) FOC76_RS17445 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase FOC76_RS17455 ENOG4105CIH Imidazole acetol-phosphate transaminase FOC76_RS17475 ENOG41082JN Transcriptional regulator FOC76_RS17480 ENOG4105EYF MMPL domain protein FOC76_RS17490 ENOG4105C5H ABC transporter FOC76_RS17495 ENOG4105E0M Sulfatase FOC76_RS17500 ENOG4108ZCF integral membrane protein FOC76_RS17505 ENOG4106ETB IIa component FOC76_RS17535 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC76_RS17590 ENOG4108AQF aminoglycoside N(3)-acetyltransferase FOC76_RS17610 ENOG4105E09 nadh pyrophosphatase FOC76_RS17625 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein FOC76_RS17630 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FOC76_RS17635 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FOC76_RS17645 ENOG4105C02 permease FOC76_RS17695 ENOG4105DVE abc transporter atp-binding protein FOC76_RS17710 ENOG4108ZMI UPF0477 protein FOC76_RS17725 ENOG4105CHM Aminotransferase FOC76_RS17765 ENOG41089UC methyltransferase, type 11 FOC76_RS17780 ENOG4107BMA Transglycosylase associated protein FOC76_RS17800 ENOG4106K7D Major facilitator family transporter FOC76_RS17805 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FOC76_RS17865 ENOG4105EPR degv family FOC76_RS17875 ENOG4105DPN Oligoendopeptidase f FOC76_RS17910 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC76_RS17915 ENOG4105BZU Histidine kinase FOC76_RS17920 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) FOC76_RS17970 ENOG4105DTQ mandelate racemase muconate lactonizing FOC76_RS18000 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC76_RS18015 ENOG4107T5V SNARE associated Golgi FOC76_RS18060 ENOG41080HI glycine oxidase FOC76_RS18065 ENOG4105CTU Proline racemase FOC76_RS18070 ENOG4105CTU Proline racemase FOC76_RS18075 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC76_RS18080 ENOG4105C26 Dehydrogenase FOC76_RS18085 ENOG4105BZG amino acid carrier protein FOC76_RS18105 ENOG4108M1A Chitin-binding protein FOC76_RS18155 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC76_RS18175 ENOG4105EEM helicase FOC76_RS18195 ENOG4108Z7F N-acetyltransferase FOC76_RS18230 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FOC76_RS18240 ENOG4105MSB protein, conserved in bacteria FOC76_RS18245 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC76_RS18270 ENOG41087PP glycosyltransferase MGT family FOC76_RS18275 ENOG4108M1A Chitin-binding protein FOC76_RS18280 ENOG41082BV acetyltransferase FOC76_RS18310 ENOG4108IJ7 Glycine betaine FOC76_RS18315 ENOG4107SQ8 Glycine betaine FOC76_RS18355 ENOG4105RHY Pfam:UPF0157 FOC76_RS18360 ENOG4105E1F short-chain dehydrogenase reductase FOC76_RS18370 ENOG4107RUY (E1 component), alpha subunit FOC76_RS18380 ENOG4107QKR Dehydrogenase FOC76_RS18405 ENOG4105E98 transcriptional regulator DeoR family FOC76_RS18425 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FOC76_RS18445 ENOG4107Z3H Transcriptional regulator, TetR family FOC76_RS18485 ENOG4105MSI germination protein ypeb FOC76_RS18535 ENOG4105CIS alcohol dehydrogenase FOC76_RS18545 ENOG4105FDR Membrane FOC76_RS18565 ENOG4108IUM Glycogen debranching enzyme FOC76_RS18610 ENOG4107VFR oxidoreductase FOC76_RS18645 ENOG4105PKS Excinuclease abc c subunit domain protein FOC76_RS18680 ENOG4105KWG Pfam:DUF1696 FOC76_RS18685 ENOG4108NRW Phospholipase, patatin family FOC76_RS18710 ENOG4108XI2 Domain of unknown function (DUF1963) FOC76_RS18740 ENOG4108Z4K mutator MutT protein FOC76_RS18745 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC76_RS18750 ENOG4105E09 nadh pyrophosphatase FOC76_RS18765 ENOG4105FCD Major Facilitator FOC76_RS18810 ENOG4107Y9U Membrane FOC76_RS18830 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC76_RS18845 ENOG4107Y80 Major Facilitator superfamily FOC76_RS18855 ENOG4108V4B ThiJ pfpI FOC76_RS18905 ENOG4105CHR reductase FOC76_RS18910 ENOG4108IG5 Transcriptional regulator FOC76_RS18915 ENOG4105CJN penicillin-binding protein FOC76_RS18920 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOC76_RS18925 ENOG4105CB2 alcohol dehydrogenase FOC76_RS18930 ENOG4105RHY Pfam:UPF0157 FOC76_RS18940 ENOG4108HGU Histidine kinase FOC76_RS18975 ENOG4105BZU Histidine kinase FOC76_RS18980 ENOG410667J hydrolase FOC76_RS19065 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC76_RS19135 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FOC76_RS19145 ENOG4105CAR Terminase, large subunit FOC76_RS19195 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin FOC76_RS19255 ENOG4105KRN Transcriptional regulator, abrb family FOC76_RS19265 ENOG4106CVF DNA replication protein FOC76_RS19315 ENOG4105VTR Integrase FOC76_RS19340 ENOG4105ETU transcriptional activator (TenA FOC76_RS19355 ENOG4105D6E homoserine dehydrogenase FOC76_RS19425 ENOG4105DK7 lysyl-tRNA synthetase FOC76_RS19435 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein FOC76_RS19445 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FOC76_RS19455 ENOG410900G Protein of unknown function (DUF421) FOC76_RS19475 ENOG4105EFA 4-hydroxyphenylacetate FOC76_RS19520 ENOG41089UC methyltransferase, type 11 FOC76_RS19530 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr FOC76_RS19540 ENOG4107Y80 Major Facilitator superfamily FOC76_RS19550 ENOG4105FQP Beta-lactamase FOC76_RS19565 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOC76_RS19600 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FOC76_RS19615 ENOG4105T9C HD domain FOC76_RS19640 ENOG4105DBI uridine monophosphokinase FOC76_RS19655 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC76_RS19660 ENOG4107QX3 carboxylase FOC76_RS19665 ENOG4105E39 Enoyl-CoA hydratase FOC76_RS19670 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FOC76_RS19675 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit FOC76_RS19680 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC76_RS19685 ENOG4105C1G acyl-Coa dehydrogenase FOC76_RS19700 ENOG4107Z3H Transcriptional regulator, TetR family FOC76_RS19710 ENOG4105CJ1 ABC, transporter FOC76_RS19725 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) FOC76_RS19735 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC76_RS19815 ENOG4105BZU Histidine kinase FOC76_RS19840 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FOC76_RS19845 ENOG4105WH1 Two component transcriptional regulator luxr family FOC76_RS19850 ENOG4108XG2 Histidine kinase FOC76_RS19855 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FOC76_RS19900 ENOG4105EXC Acyl-transferase FOC76_RS19920 ENOG4105DH8 myo-inositol catabolism FOC76_RS19925 ENOG4105D2N Aldolase FOC76_RS19950 ENOG4105CK5 oxidoreductase FOC76_RS19955 ENOG4105IE8 Alpha-ketoglutarate permease FOC76_RS19960 ENOG4105ETE Transcriptional regulator (LacI family FOC76_RS19965 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOC76_RS19975 ENOG4107RF6 penicillin-binding protein FOC76_RS19980 ENOG4107RF6 penicillin-binding protein FOC76_RS19995 ENOG4107RVG penicillin-binding protein FOC76_RS20020 ENOG4105EQK -acetyltransferase FOC76_RS20030 ENOG4105CIN aminoacyl-histidine dipeptidase FOC76_RS20055 ENOG4105K56 Transcriptional regulator FOC76_RS20060 ENOG4107RA9 decarboxylase FOC76_RS20065 ENOG4108I0C methyltransferase FOC76_RS20075 ENOG41088CC tellurite resistance protein tehB FOC76_RS20080 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC76_RS20095 ENOG4108RZE Tetr family transcriptional regulator FOC76_RS20110 ENOG4105C1J atp-dependent rna helicase FOC76_RS20125 ENOG4105D7V transposase FOC76_RS20130 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FOC76_RS20150 ENOG4108INS Transcriptional regulator FOC76_RS20170 ENOG4105RD7 BadF BadG BcrA BcrD FOC76_RS20195 ENOG4105F32 YngK protein FOC76_RS20220 ENOG4108KPJ rna polymerase sigma factor FOC76_RS20225 ENOG4108KJ0 anaerobic glycerol-3-phosphate dehydrogenase, subunit B FOC76_RS20235 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FOC76_RS20265 ENOG4108JCI Transcriptional regulator FOC76_RS20285 ENOG4105BZ1 (ABC) transporter FOC76_RS20290 ENOG4105BZ1 (ABC) transporter FOC76_RS20305 ENOG4108RPX mosc domain containing protein FOC76_RS20310 ENOG4105DND Transcriptional regulator FOC76_RS20325 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC76_RS20330 ENOG4107V2S Transcriptional regulator FOC76_RS20340 ENOG410667J hydrolase FOC76_RS20360 ENOG4105VEQ Cold shock protein FOC76_RS20370 ENOG41068WN FOC76_RS20380 ENOG4105C1Q protoporphyrinogen oxidase FOC76_RS20385 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) FOC76_RS20410 ENOG4105WCN acetyltransferase FOC76_RS20430 ENOG4105EYF MMPL domain protein FOC76_RS20440 ENOG4105C5X domain protein FOC76_RS20455 ENOG4107RU9 Transcriptional regulator, Crp Fnr family FOC76_RS20465 ENOG41081I9 integral membrane protein FOC76_RS20490 ENOG4108D32 Methyltransferase FOC76_RS20525 ENOG4105C19 ABC transporter FOC76_RS20535 ENOG4105C22 threonyL-tRNA synthetase FOC76_RS20540 ENOG4105FE9 pseudouridine synthase FOC76_RS20560 ENOG4105BZG amino acid carrier protein FOC76_RS20580 ENOG4105K70 DNA-binding protein FOC76_RS20595 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC76_RS20605 ENOG4105CEY Amp-dependent synthetase and ligase FOC76_RS20610 ENOG4105WQI isochorismatase FOC76_RS20615 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FOC76_RS20620 ENOG4105E4F Isochorismate synthase FOC76_RS20625 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FOC76_RS20630 ENOG4105FCD Major Facilitator FOC76_RS20655 ENOG4107RFY SbcCD D subunit FOC76_RS20670 ENOG4105E39 Enoyl-CoA hydratase FOC76_RS20675 ENOG4105N14 lysine exporter protein LysE YggA FOC76_RS20685 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOC76_RS20690 ENOG4105C1G acyl-Coa dehydrogenase FOC76_RS20695 ENOG4105CR4 methylisocitrate lyase FOC76_RS20700 ENOG4105DXD 2-methylcitrate dehydratase FOC76_RS20710 ENOG4105W8X HesB YadR YfhF-family protein FOC76_RS20725 ENOG4105BZ4 penicillin-binding protein FOC76_RS20745 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FOC76_RS20780 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC76_RS20815 ENOG4108AEY RNA polymerase sigma factor FOC76_RS20870 ENOG4105SZ6 Thioredoxin FOC76_RS20880 ENOG410841Q phosphoesterase PA-phosphatase related protein FOC76_RS20885 ENOG4108N23 SpoOM-related protein FOC76_RS20925 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FOC76_RS20930 ENOG4108JUB Transcriptional regulator FOC76_RS20935 ENOG4108TSC N-acetyltransferase FOC76_RS20940 ENOG4107S4Y M20 DapE family protein YgeY FOC76_RS20955 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC76_RS20980 ENOG4105C37 (CBS) domain FOC76_RS21015 ENOG4105E90 ABC transporter FOC76_RS21020 ENOG4108IJ8 ABC transporter FOC76_RS21050 ENOG4108YV3 Protein of unknown function (DUF2711) FOC76_RS21095 ENOG4105WH1 Two component transcriptional regulator luxr family FOC76_RS21100 ENOG4105BZU Histidine kinase FOC76_RS21105 ENOG4105D8X mechanosensitive ion channel FOC76_RS21115 ENOG4105E09 nadh pyrophosphatase FOC76_RS21135 ENOG4105F0I Aminotransferase FOC76_RS21140 ENOG4108MES Periplasmic binding protein FOC76_RS21160 ENOG4105CAQ asparagine synthetase FOC76_RS21165 ENOG4107Y70 Heat shock protein FOC76_RS21170 ENOG4108KF3 Electron transport protein SCO1 SenC FOC76_RS21175 ENOG4105E8R UPF0173 metal-dependent hydrolase FOC76_RS21180 ENOG4108RCR degv family FOC76_RS21190 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FOC76_RS21200 ENOG4108UT2 hemolysin iii FOC76_RS21205 ENOG4105E9Q Acyl-transferase FOC76_RS21215 ENOG4107RVG penicillin-binding protein FOC76_RS21235 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) FOC76_RS21255 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 FOC76_RS21280 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FOC76_RS21285 ENOG4105KD7 acetyltransferase FOC76_RS21300 ENOG4105C0A alcohol dehydrogenase FOC76_RS21305 ENOG4105CY2 Citrate transporter FOC76_RS21310 ENOG4107XGZ Hydrolase FOC76_RS21330 ENOG4105C8J )-transporter FOC76_RS21390 ENOG4105EC2 ftsk spoIIIe FOC76_RS21410 ENOG4105C5S asparaginyl-tRNA synthetase FOC76_RS21460 ENOG4107YX5 Pfam:DUF548 FOC76_RS21480 ENOG4108UUM single-stranded DNA-binding protein FOC76_RS21495 ENOG4105C5H ABC transporter FOC76_RS21515 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC76_RS21530 ENOG4105MCT stage V sporulation protein S FOC76_RS21555 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) FOC76_RS21560 ENOG4108IFG nitrite reductase, (NAD(P)H) FOC76_RS21565 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit FOC76_RS21570 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC76_RS21575 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC76_RS21580 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC76_RS21610 ENOG4108ZAF Molybdopterin FOC76_RS21615 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC76_RS21620 ENOG4105D06 uba thif-type nad fad binding protein FOC76_RS21625 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC76_RS21630 ENOG4107V6Q Cyclic nucleotide-binding domain FOC76_RS21640 ENOG4105R3A Nitrate reductase FOC76_RS21645 ENOG4108IUE nitrate reductase beta subunit FOC76_RS21665 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC76_RS21680 ENOG4108V06 Glutathione peroxidase FOC76_RS21690 ENOG4105CNW domain protein FOC76_RS21710 ENOG4105EMN RNA polymerase sigma factor FOC76_RS21715 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FOC76_RS21725 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FOC76_RS21750 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FOC76_RS21775 ENOG4105KBJ sporulation protein ytfj FOC76_RS21815 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC76_RS21845 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC76_RS21850 ENOG4108JYZ YitT family FOC76_RS21855 ENOG41087PP glycosyltransferase MGT family FOC76_RS21875 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC76_RS21885 ENOG4108X4Q Hydrolase FOC76_RS21895 ENOG41069HH 4-oxalocrotonate tautomerase FOC76_RS21915 ENOG4105IKQ hydratase FOC76_RS21925 ENOG4105KME endoribonuclease L-psp FOC76_RS21940 ENOG4105U1N riboflavin FOC76_RS21950 ENOG4105EFA 4-hydroxyphenylacetate FOC76_RS21970 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FOC76_RS21980 ENOG4108VXD carboxy-peptidase FOC76_RS21990 ENOG4108ZRV stage ii sporulation protein p FOC76_RS22010 ENOG4108Z7R Chaperone CsaA FOC76_RS22035 ENOG4105C37 (CBS) domain FOC76_RS22040 ENOG4105SXS Protein of unknown function (DUF456) FOC76_RS22060 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC76_RS22070 ENOG4108S4H thioesterase Superfamily protein FOC76_RS22080 ENOG4108PJD permease FOC76_RS22095 ENOG4107T5V SNARE associated Golgi FOC76_RS22115 ENOG4105CVJ phosphoglycerate mutase FOC76_RS22140 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC76_RS22150 ENOG4105K4T epimerase FOC76_RS22160 ENOG4105DSE periplasmic solute binding protein FOC76_RS22170 ENOG4105CKI cobalamin synthesis protein FOC76_RS22175 ENOG4107QM2 Aldo Keto reductase FOC76_RS22180 ENOG4105VMI -acetyltransferase FOC76_RS22195 ENOG4105DEN Luciferase family FOC76_RS22210 ENOG4108WPJ Ferritin-like domain FOC76_RS22215 ENOG4108K88 Membrane FOC76_RS22255 ENOG4107XZQ multidrug resistance protein FOC76_RS22260 ENOG4105CPC Aldo Keto reductase FOC76_RS22265 ENOG4105YVS arsR family transcriptional regulator FOC76_RS22270 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase FOC76_RS22280 ENOG4105KRN Transcriptional regulator, abrb family FOC76_RS22330 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC76_RS22335 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FOC76_RS22345 ENOG4105YWU small acid-soluble spore protein FOC76_RS22350 ENOG4108WBH protein TIM barrel FOC76_RS22365 ENOG4105CEY Amp-dependent synthetase and ligase FOC76_RS22370 ENOG4105DUU IucA IucC family protein FOC76_RS22380 ENOG4105VRR gCN5-related N-acetyltransferase FOC76_RS22385 ENOG4105KT7 mgtC SapB transporter FOC76_RS22400 ENOG4105BZU Histidine kinase FOC76_RS22405 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC76_RS22415 ENOG4108KGH TRANSCRIPTIONal FOC76_RS22440 ENOG4105D6E homoserine dehydrogenase FOC76_RS22465 ENOG41075D4 Aminoglycoside 6-adenylyltransferase FOC76_RS22485 ENOG4105BZU Histidine kinase FOC76_RS22490 ENOG4105EFI regulatoR FOC76_RS22495 ENOG4105BZ1 (ABC) transporter FOC76_RS22540 ENOG4108UT6 Transferase hexapeptide repeat containing protein FOC76_RS22550 ENOG4105K64 Glycosyl transferase, family 2 FOC76_RS22560 ENOG4108JJ8 (ABC) transporter FOC76_RS22565 ENOG4108JJ9 ABC, transporter FOC76_RS22570 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC76_RS22575 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC76_RS22595 ENOG4105MDS 4-oxalocrotonate tautomerase FOC76_RS22605 ENOG4105SKE transcriptional Regulator LysR family FOC76_RS22615 ENOG4105C32 Amino acid ABC transporter (Permease) FOC76_RS22620 ENOG4108IV0 ABC, transporter FOC76_RS22625 ENOG4105C0Z ABC transporter FOC76_RS22640 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC76_RS22645 ENOG4108Z7G MaoC domain protein dehydratase FOC76_RS22660 ENOG4105CKI cobalamin synthesis protein FOC76_RS22675 ENOG4106F5Q Membrane FOC76_RS22685 ENOG4108TVJ Nitroreductase FOC76_RS22690 ENOG4107ZXU DSBA oxidoreductase FOC76_RS22695 ENOG4108Z40 Transcriptional regulator FOC76_RS22700 ENOG4105GZI Transcriptional regulator FOC76_RS22705 ENOG4107RT3 EamA-like transporter family FOC76_RS22710 ENOG4105KTB nuclear export factor GLE1 FOC76_RS22715 ENOG4108T5E Copper resistance protein FOC76_RS22760 ENOG4107R16 Multicopper oxidase FOC76_RS22765 ENOG4107RAQ aminopeptidase FOC76_RS22790 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) FOC76_RS22795 ENOG4105D9N nucleoside FOC76_RS22805 ENOG4107RHR regulatoR FOC76_RS22845 ENOG4105C0X amino acid FOC76_RS22850 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FOC76_RS22865 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) FOC76_RS22885 ENOG41068WN FOC76_RS22945 ENOG4105CYC Transferase FOC76_RS22950 ENOG4105DY9 regulatoR FOC76_RS22960 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FOC76_RS22965 ENOG4105C6X Major Facilitator FOC76_RS22990 ENOG4105C7B Threonine dehydratase FOC76_RS23010 ENOG4105C7K acetolactate synthase FOC76_RS23015 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC76_RS23020 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FOC76_RS23040 ENOG4105H67 Protein of unknown function (DUF421) FOC76_RS23045 ENOG4105X5K response regulator receiver protein FOC76_RS23055 ENOG4105C8J )-transporter FOC76_RS23075 ENOG4105C6T cysteine synthase FOC76_RS23080 ENOG4105EU0 Major facilitator Superfamily FOC76_RS23090 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOC76_RS23105 ENOG4105DXI Major Facilitator superfamily FOC76_RS23115 ENOG4105U3E Transcriptional regulator FOC76_RS23120 ENOG4105CSR polyphosphate kinase 2 FOC76_RS23155 ENOG4105FVX FOC76_RS23180 ENOG41067QW Transcriptional regulator FOC76_RS23210 ENOG4105C6K Malic enzyme FOC76_RS23215 ENOG4108IJ0 Aspartate ammonia-lyase FOC76_RS23225 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FOC76_RS23245 ENOG4105CJ1 ABC, transporter FOC76_RS23280 ENOG4106BRA Membrane FOC76_RS23300 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC76_RS23305 ENOG4107QIV Cytochrome c biogenesis protein FOC76_RS23325 ENOG4105EC3 peptidase S51, dipeptidase E FOC76_RS23330 ENOG4107QJQ Mate efflux family protein FOC76_RS23340 ENOG4105C5X domain protein FOC76_RS23350 ENOG4105C9Q fumarate hydratase class II FOC76_RS23355 ENOG4105EMU Dehydrogenase FOC76_RS23360 ENOG4105VUF Transcriptional regulator FOC76_RS23365 ENOG4105DFD Na H antiporter FOC76_RS23380 ENOG4108PJD permease FOC76_RS23385 ENOG4105CKI cobalamin synthesis protein FOC76_RS23390 ENOG4108UZ3 Transporter FOC76_RS23395 ENOG4105DRR Transcriptional regulator, GntR family FOC76_RS23405 ENOG4105PGM cation diffusion facilitator family transporter FOC76_RS23425 ENOG4105CAQ asparagine synthetase FOC76_RS23435 ENOG4105K56 Transcriptional regulator FOC76_RS23500 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component FOC76_RS23505 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FOC76_RS23510 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC76_RS23545 ENOG4108U4N (sortase) family FOC76_RS23575 ENOG4105KAC Antibiotic biosynthesis monooxygenase FOC76_RS23610 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC76_RS23615 ENOG4105KTQ flagellar basal-body rod protein FOC76_RS23620 ENOG4105FZW flagellar biosynthesis regulator FlhF FOC76_RS23625 ENOG4105D7B Flagellar biosynthesis protein flha FOC76_RS23630 ENOG4105D00 flagellar biosynthetic protein flhB FOC76_RS23640 ENOG4105VS8 Flagellar biosynthetic protein fliq FOC76_RS23645 ENOG4105CN7 Flagellar biosynthetic protein FliP FOC76_RS23655 ENOG4105DD5 Flagellar motor switch protein FOC76_RS23660 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOC76_RS23670 ENOG4105E4C Lytic transglycosylase catalytic FOC76_RS23675 ENOG4105I03 Flagellin FOC76_RS23690 ENOG4107R88 Chemotaxis protein (CheV) FOC76_RS23705 ENOG4105BZE flagellar hook protein, FlgE FOC76_RS23735 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOC76_RS23740 ENOG4107U2N Flagellar M-ring protein FOC76_RS23750 ENOG4108ZC9 flagellar basal-body rod protein flgc FOC76_RS23755 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FOC76_RS23770 ENOG410804A Flagellar hook-associated 2 domain-containing protein FOC76_RS23775 ENOG4105DTJ flagellar hook-associated protein FOC76_RS23780 ENOG4105E1Q flagellar hook-associated protein FOC76_RS23800 ENOG4105BZU Histidine kinase FOC76_RS23815 ENOG4105DD5 Flagellar motor switch protein FOC76_RS23820 ENOG4105CBS Chea signal transduction histidine kinase FOC76_RS23825 ENOG4107YTP response regulator receiver protein FOC76_RS23830 ENOG4105ER2 Ompa motb domain protein FOC76_RS23835 ENOG4107R0U MotA TolQ exbB proton channel FOC76_RS23845 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FOC76_RS23900 ENOG41080C8 DUF218 domain FOC76_RS23905 ENOG4105H67 Protein of unknown function (DUF421) FOC76_RS23915 ENOG4108Z5V transcriptional regulator, merr family FOC76_RS23920 ENOG4105CN5 Metallo-Beta-Lactamase FOC76_RS23925 ENOG4107RWR Sodium hydrogen exchanger FOC76_RS23935 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC76_RS24000 ENOG41081VK Ribonuclease FOC76_RS24020 ENOG4108SZE gCN5-related N-acetyltransferase FOC76_RS24035 ENOG4105CPK Glycosyl transferase (Group 1 FOC76_RS24070 ENOG4105EXC Acyl-transferase FOC76_RS24095 ENOG4106032 Glutathionylspermidine synthase FOC76_RS24120 ENOG4105KHC sulfurtransferase FOC76_RS24130 ENOG4108W0I acetyltransferase FOC76_RS24140 ENOG410890F Dynamin family FOC76_RS24145 ENOG4105DHF Membrane FOC76_RS24150 ENOG4105C2W permease FOC76_RS24155 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) FOC76_RS24160 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC76_RS24170 ENOG4105CTD carboxy-peptidase FOC76_RS24175 ENOG4105DVT helicase FOC76_RS24185 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FOC76_RS24255 ENOG4105CSM endonuclease III FOC76_RS24275 ENOG4105YAC FOC76_RS24280 ENOG4105DVT helicase FOC76_RS24315 ENOG4105CPK Glycosyl transferase (Group 1 FOC76_RS24320 ENOG4105FJR Lmbe family FOC76_RS24335 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase FOC76_RS24340 ENOG4108JYZ YitT family FOC76_RS24375 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FOC76_RS24380 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) FOC76_RS24395 ENOG41068YB TPR repeat-containing protein FOC76_RS24420 ENOG4105EAH synthase FOC76_RS24430 ENOG4105XXQ heptaprenyl diphosphate synthase component I FOC76_RS24445 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) FOC76_RS24475 ENOG41065D1 FOC76_RS24480 ENOG4105S2F FOC76_RS24515 ENOG4105HDK L-asparaginase FOC76_RS24520 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase FOC76_RS24545 ENOG4108S6Z Negative regulator of genetic competence FOC76_RS24550 ENOG4107X2D transcriptional regulator, merr family FOC76_RS24555 ENOG4107RGJ metallophosphoesterase FOC76_RS24565 ENOG4105I7S Abortive infection protein FOC76_RS24570 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC76_RS24585 ENOG4108SAX Membrane FOC76_RS24595 ENOG41063SB peptidase FOC76_RS24600 ENOG4108WBT adenosyltransferase FOC76_RS24605 ENOG4105BZU Histidine kinase FOC76_RS24610 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC76_RS24615 ENOG4105CRE cytochrome C FOC76_RS24620 ENOG4107TWT Cytochrome c biogenesis protein FOC76_RS24630 ENOG4105FE9 pseudouridine synthase FOC76_RS24640 ENOG4108JIC nucleoside recognition domain protein FOC76_RS24645 ENOG4105DZ1 carboxypeptidase FOC76_RS24650 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC76_RS24675 ENOG4105D3A purine nucleoside phosphorylase DeoD-type FOC76_RS24680 ENOG4105BZU Histidine kinase FOC76_RS24695 ENOG4105I3N Conserved Protein FOC76_RS24700 ENOG4105BZU Histidine kinase FOC76_RS24715 ENOG4105BZ4 penicillin-binding protein FOC76_RS24720 ENOG4107GRR phosphate transport regulator FOC76_RS24725 ENOG4105CJ3 phosphate transporter FOC76_RS24770 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FOC76_RS24790 ENOG4105WH1 Two component transcriptional regulator luxr family FOC76_RS24795 ENOG4105ENE Histidine kinase FOC76_RS24815 ENOG4105DFD Na H antiporter FOC76_RS24840 ENOG4105C8J )-transporter FOC76_RS24845 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC76_RS24850 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC76_RS24855 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC76_RS24865 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FOC76_RS24870 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) FOC76_RS24890 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FOC76_RS24900 ENOG4105E0M Sulfatase FOC76_RS24905 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC76_RS24920 ENOG4107RVV histidinol phosphate phosphatase, hisj family FOC76_RS24995 ENOG4108ZP8 Acetolactate synthase small subunit FOC76_RS25000 ENOG4105C7K acetolactate synthase FOC76_RS25005 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC76_RS25025 ENOG4105KBJ sporulation protein ytfj FOC76_RS25030 ENOG41063Y9 FOC76_RS25035 ENOG4105CZN Potassium uptake protein FOC76_RS25070 ENOG4107QMU Mate efflux family protein FOC76_RS25105 ENOG4105NQC Flavodoxin FOC76_RS25130 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FOC76_RS25140 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC76_RS25145 ENOG4105EA8 2-Nitropropane dioxygenase FOC76_RS25150 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC76_RS25190 ENOG4105CJ1 ABC, transporter FOC76_RS25200 ENOG4105CZV ABC transporter FOC76_RS25205 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC76_RS25210 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FOC76_RS25225 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) FOC76_RS25265 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FOC76_RS25270 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase FOC76_RS25280 ENOG4105BZU Histidine kinase FOC76_RS25285 ENOG4106DF1 FOC76_RS25295 ENOG41090MY MarR family Transcriptional regulator FOC76_RS25300 ENOG4105BZU Histidine kinase FOC76_RS25310 ENOG4105PXI polysaccharide deacetylase FOC76_RS25320 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) FOC76_RS25330 ENOG4105E98 transcriptional regulator DeoR family FOC76_RS25350 ENOG4107RCV ABC transporter, permease FOC76_RS25355 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC76_RS25360 ENOG4105C4Y ABC transporter FOC76_RS25390 ENOG4105CHR reductase FOC76_RS25410 ENOG4108Z7G MaoC domain protein dehydratase FOC76_RS25415 ENOG410681C small acid-soluble spore protein FOC76_RS25420 ENOG4105CZN Potassium uptake protein FOC76_RS25425 ENOG4107TS3 membrane protein, TerC FOC76_RS25430 ENOG4108QTI )-transporter FOC76_RS25440 ENOG4106A3R peptidase FOC76_RS25465 ENOG4105BZU Histidine kinase FOC76_RS25470 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC76_RS25485 ENOG4105CQB FAD linked oxidase domain protein FOC76_RS25490 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FOC76_RS25495 ENOG4105K4I Scp-like extracellular FOC76_RS25505 ENOG4108YBP pseudouridine synthase FOC76_RS25515 ENOG4105EYF MMPL domain protein FOC76_RS25525 ENOG4107RUE extracellular solute-binding protein family 1 FOC76_RS25530 ENOG4105D38 putrescine abc transporter FOC76_RS25535 ENOG4105F38 ABC transporter, permease FOC76_RS25545 ENOG4105C26 Dehydrogenase FOC76_RS25560 ENOG4108IMY Transcriptional regulator FOC76_RS25580 ENOG4105VFR signal peptidase FOC76_RS25585 ENOG4105DZ1 carboxypeptidase FOC76_RS25595 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) FOC76_RS25670 ENOG4105VZ8 Transcriptional regulator FOC76_RS25680 ENOG4105C7S Dehydrogenase FOC76_RS25760 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FOC76_RS25780 ENOG4105DDQ anthranilate synthase FOC76_RS25790 ENOG4105CK7 Sodium proline symporter FOC76_RS25865 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase FOC76_RS25875 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase FOC76_RS25880 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FOC76_RS25900 ENOG4107TVC Glycosyl transferase, family 2 FOC76_RS25920 ENOG4105K64 Glycosyl transferase, family 2 FOC76_RS25940 ENOG4105EMS pseudouridine synthase FOC76_RS25960 ENOG4105MIX Adenylate cyclase FOC76_RS25965 ENOG4108Z18 K06886 hemoglobin FOC76_RS25980 ENOG4105DPN Oligoendopeptidase f FOC76_RS25990 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC76_RS26000 ENOG4108ZCF integral membrane protein FOC76_RS26020 ENOG4105UQX Mate efflux family protein FOC76_RS26025 ENOG4108JQ7 (ABC) transporter FOC76_RS26035 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC76_RS26040 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC76_RS26055 ENOG4105C31 Tryptophanyl-tRNA synthetase FOC76_RS26070 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FOC76_RS26075 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC76_RS26110 ENOG4108KP7 hydrolase FOC76_RS26120 ENOG41073B9 FOC76_RS26125 ENOG4107AYK membrAne FOC76_RS26135 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC76_RS26140 ENOG4105QNR S1 RNA binding domain protein FOC76_RS26160 ENOG4105BZU Histidine kinase FOC76_RS26165 ENOG4105CH6 catalase FOC76_RS26175 ENOG4105CAQ asparagine synthetase FOC76_RS26200 ENOG4105ERH Fumarylacetoacetate hydrolase FOC76_RS26290 ENOG4105XVF Competence transcription factor FOC76_RS26320 ENOG4107QP3 malate synthase g FOC76_RS26345 ENOG4105C8Q Methyl-accepting chemotaxis FOC76_RS26350 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 FOC76_RS26375 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC76_RS26395 ENOG41086D8 Transcriptional regulator FOC76_RS26400 ENOG4108AEY RNA polymerase sigma factor FOC76_RS26410 ENOG4107TVP HD domain protein FOC76_RS26415 ENOG4107RN3 metallophosphoesterase FOC76_RS26420 ENOG4105ENX hydrolase FOC76_RS26445 ENOG4105CNA YD repeat protein FOC76_RS26460 ENOG4105CEY Amp-dependent synthetase and ligase FOC76_RS26470 ENOG4105DF9 Lipoate-protein, ligase FOC76_RS26475 ENOG4108RQ5 Beta-lactamase domain-containing protein FOC76_RS26480 ENOG4106AXD FOC76_RS26490 ENOG4105D29 Helix-turn-helix type 11 domain protein FOC76_RS26515 ENOG4105ECB domain protein FOC76_RS26545 ENOG4105C1Q protoporphyrinogen oxidase FOC76_RS26550 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FOC76_RS26560 ENOG4105BZ4 penicillin-binding protein FOC76_RS26565 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation FOC76_RS26570 ENOG4105CKV Membrane FOC76_RS26575 ENOG410905X membrane-flanked domain protein FOC76_RS26605 ENOG4105CKV Membrane FOC76_RS26610 ENOG410905X membrane-flanked domain protein FOC76_RS26645 ENOG4105K59 histidine triad (HIT) protein FOC76_RS26670 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC76_RS26675 ENOG4105EEM helicase FOC76_RS26695 ENOG4105EMN RNA polymerase sigma factor FOC76_RS26725 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FOC76_RS26740 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FOC76_RS26760 ENOG4108MUZ hydrolase FOC76_RS26815 ENOG4105ED2 Beta-lactamase FOC76_RS26825 ENOG4106D4I domain protein FOC76_RS26830 ENOG4107VRP DNA repair exonuclease FOC76_RS26855 ENOG4108VB1 regulatoR FOC76_RS26860 ENOG4105ENE Histidine kinase FOC76_RS26910 ENOG4105BZU Histidine kinase FOC76_RS26915 ENOG4105BZU Histidine kinase FOC76_RS26920 ENOG4108MJI response regulator FOC76_RS26930 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC76_RS26940 ENOG4105WN5 stage II sporulation protein FOC76_RS27005 ENOG4108JJA ABC, transporter FOC76_RS27045 ENOG41067QW Transcriptional regulator FOC76_RS27065 ENOG4107QJE Chromosome Partitioning Protein FOC76_RS27080 ENOG4105C19 ABC transporter