locus-tag	class	description
C0W57_RS00030	COG2851	Citrate transporter
C0W57_RS00035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0W57_RS00040	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C0W57_RS00070	COG0024	Methionine aminopeptidase
C0W57_RS00075	COG1263	PTS System
C0W57_RS00075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0W57_RS00085	COG1368	sulfuric ester hydrolase activity
C0W57_RS00095	COG0071	Belongs to the small heat shock protein (HSP20) family
C0W57_RS00110	COG1263	PTS System
C0W57_RS00110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0W57_RS00115	COG0366	Alpha amylase catalytic
C0W57_RS00120	COG2188	Transcriptional regulator
C0W57_RS00125	COG0778	Nitroreductase
C0W57_RS00140	COG0737	Belongs to the 5'-nucleotidase family
C0W57_RS00145	COG0693	protein deglycase activity
C0W57_RS00150	COG1609	Transcriptional regulator
C0W57_RS00165	COG2814	Major facilitator Superfamily
C0W57_RS00175	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C0W57_RS00180	COG4980	gas vesicle protein
C0W57_RS00185	COG1295	ribonuclease BN
C0W57_RS00190	COG0477	Major facilitator Superfamily
C0W57_RS00195	COG0387	Pfam Sodium calcium exchanger
C0W57_RS00205	COG0668	transmembrane transport
C0W57_RS00210	COG0535	radical SAM domain protein
C0W57_RS00220	COG0726	polysaccharide deacetylase
C0W57_RS00225	COG2084	Dehydrogenase
C0W57_RS00235	COG0598	Magnesium transport protein CorA
C0W57_RS00240	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C0W57_RS00245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C0W57_RS00260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C0W57_RS00265	COG4637	Psort location Cytoplasmic, score
C0W57_RS00270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C0W57_RS00275	COG0022	dehydrogenase e1 component
C0W57_RS00280	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0W57_RS00285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0W57_RS00290	COG3284	Transcriptional regulator
C0W57_RS00300	COG1486	melibiose metabolic process
C0W57_RS00305	COG1737	Transcriptional regulator
C0W57_RS00310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0W57_RS00310	COG1263	PTS System
C0W57_RS00315	COG5434	Belongs to the glycosyl hydrolase 28 family
C0W57_RS00320	COG1132	(ABC) transporter
C0W57_RS00325	COG1132	(ABC) transporter
C0W57_RS00330	COG2259	Doxx family
C0W57_RS00335	COG2514	catechol 2,3-dioxygenase activity
C0W57_RS00350	COG1695	Transcriptional regulator
C0W57_RS00355	COG2249	NAD(P)H dehydrogenase (quinone) activity
C0W57_RS00360	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C0W57_RS00365	COG3848	Pyruvate phosphate dikinase
C0W57_RS00365	COG0574	Belongs to the PEP-utilizing enzyme family
C0W57_RS00370	COG2732	(Barnase) inhibitor
C0W57_RS00375	COG2318	DinB family
C0W57_RS00380	COG2814	Major facilitator Superfamily
C0W57_RS00385	COG1846	Transcriptional regulator
C0W57_RS00390	COG0392	lysyltransferase activity
C0W57_RS00390	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C0W57_RS00395	COG0384	phenazine biosynthesis protein PhzF
C0W57_RS00400	COG0778	Nitroreductase
C0W57_RS00415	COG1090	epimerase
C0W57_RS00430	COG2814	Major facilitator Superfamily
C0W57_RS00440	COG3591	Belongs to the peptidase S1B family
C0W57_RS00455	COG3103	Sh3 type 3 domain protein
C0W57_RS00460	COG5658	integral membrane protein
C0W57_RS00465	COG0596	Alpha beta hydrolase
C0W57_RS00470	COG0463	Glycosyl transferase, family 2
C0W57_RS00475	COG4485	Bacterial membrane protein, YfhO
C0W57_RS00480	COG1988	membrane-bound metal-dependent
C0W57_RS00485	COG1194	a g-specific adenine glycosylase
C0W57_RS00495	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS00515	COG1132	(ABC) transporter
C0W57_RS00520	COG4129	membrane
C0W57_RS00530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C0W57_RS00535	COG0735	belongs to the Fur family
C0W57_RS00640	COG4974	Belongs to the 'phage' integrase family
C0W57_RS00700	COG1484	DNA-dependent DNA replication
C0W57_RS00725	COG3655	Transcriptional regulator
C0W57_RS00765	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0W57_RS00765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0W57_RS00780	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C0W57_RS00805	COG1780	Probably involved in ribonucleotide reductase function
C0W57_RS00810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0W57_RS00820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0W57_RS00830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0W57_RS00835	COG0756	dUTP diphosphatase activity
C0W57_RS00845	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
C0W57_RS00900	COG1793	dna ligase
C0W57_RS00925	COG5434	Belongs to the glycosyl hydrolase 28 family
C0W57_RS00925	COG3420	alginic acid biosynthetic process
C0W57_RS00930	COG4195	phage-related replication protein
C0W57_RS00940	COG1216	Glycosyl transferase, family 2
C0W57_RS01010	COG0740	serine-type endopeptidase activity
C0W57_RS01055	COG3953	SLT domain
C0W57_RS01055	COG5280	Phage tail tape measure protein TP901
C0W57_RS01070	COG5434	Belongs to the glycosyl hydrolase 28 family
C0W57_RS01095	COG3409	Peptidoglycan-binding domain 1 protein
C0W57_RS01095	COG1388	LysM domain
C0W57_RS01095	COG5632	N-Acetylmuramoyl-L-alanine amidase
C0W57_RS01140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C0W57_RS01140	COG1017	nitric oxide dioxygenase activity
C0W57_RS01145	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0W57_RS01150	COG0569	domain protein
C0W57_RS01160	COG1510	regulation of RNA biosynthetic process
C0W57_RS01165	COG1012	belongs to the aldehyde dehydrogenase family
C0W57_RS01170	COG1454	alcohol dehydrogenase
C0W57_RS01180	COG2318	DinB family
C0W57_RS01185	COG1585	Membrane protein implicated in regulation of membrane protease activity
C0W57_RS01190	COG2268	Band 7 protein
C0W57_RS01195	COG3859	Proton-coupled thiamine transporter YuaJ
C0W57_RS01320	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C0W57_RS01325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C0W57_RS01330	COG1169	isochorismate synthase
C0W57_RS01340	COG0596	Alpha beta hydrolase
C0W57_RS01345	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C0W57_RS01355	COG4948	Mandelate Racemase Muconate Lactonizing
C0W57_RS01360	COG0803	Belongs to the bacterial solute-binding protein 9 family
C0W57_RS01365	COG1121	(ABC) transporter
C0W57_RS01370	COG1321	iron dependent repressor
C0W57_RS01370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C0W57_RS01375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C0W57_RS01385	COG1294	oxidase, subunit
C0W57_RS01390	COG1271	oxidase subunit
C0W57_RS01400	COG0288	reversible hydration of carbon dioxide
C0W57_RS01425	COG0783	Belongs to the Dps family
C0W57_RS01430	COG4824	toxin secretion phage lysis holin
C0W57_RS01435	COG0494	nUDIX hydrolase
C0W57_RS01440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C0W57_RS01445	COG1116	anion transmembrane transporter activity
C0W57_RS01450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C0W57_RS01455	COG1506	peptidase
C0W57_RS01475	COG0367	asparagine synthase
C0W57_RS01480	COG1113	amino acid transport
C0W57_RS01485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C0W57_RS01490	COG2267	carboxylic ester hydrolase activity
C0W57_RS01500	COG0584	glycerophosphoryl diester phosphodiesterase
C0W57_RS01510	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C0W57_RS01515	COG1242	4 iron, 4 sulfur cluster binding
C0W57_RS01525	COG1725	Transcriptional regulator
C0W57_RS01530	COG1131	(ABC) transporter
C0W57_RS01550	COG1136	(ABC) transporter
C0W57_RS01555	COG0577	efflux transmembrane transporter activity
C0W57_RS01560	COG0745	RESPONSE REGULATOR receiver
C0W57_RS01565	COG2205	protein histidine kinase activity
C0W57_RS01570	COG1136	(ABC) transporter
C0W57_RS01575	COG0577	efflux transmembrane transporter activity
C0W57_RS01580	COG5522	Integral membrane protein (intg_mem_TP0381)
C0W57_RS01585	COG2814	Major facilitator Superfamily
C0W57_RS01590	COG1366	Belongs to the anti-sigma-factor antagonist family
C0W57_RS01590	COG2202	Pas domain
C0W57_RS01605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0W57_RS01615	COG1486	melibiose metabolic process
C0W57_RS01620	COG0395	ABC-type sugar transport system, permease component
C0W57_RS01625	COG1175	transmembrane transport
C0W57_RS01630	COG1653	transport
C0W57_RS01635	COG1609	Transcriptional regulator
C0W57_RS01650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C0W57_RS01655	COG2081	HI0933 family
C0W57_RS01660	COG2244	polysaccharide biosynthetic process
C0W57_RS01665	COG1187	pseudouridine synthase activity
C0W57_RS01670	COG1349	DNA-binding transcription factor activity
C0W57_RS01675	COG1131	(ABC) transporter
C0W57_RS01680	COG4473	ABC transporter
C0W57_RS01685	COG2252	PERMEase
C0W57_RS01690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0W57_RS01695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C0W57_RS01700	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C0W57_RS01710	COG1597	lipid kinase activity
C0W57_RS01715	COG0510	thiamine kinase activity
C0W57_RS01730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0W57_RS01735	COG0281	malic enzyme
C0W57_RS01740	COG5584	Small secreted protein
C0W57_RS01745	COG1363	Peptidase, m42
C0W57_RS01755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0W57_RS01765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0W57_RS01770	COG1674	ftsk spoiiie
C0W57_RS01780	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C0W57_RS01785	COG4980	gas vesicle protein
C0W57_RS01790	COG3118	belongs to the thioredoxin family
C0W57_RS01795	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C0W57_RS01795	COG1605	Chorismate mutase
C0W57_RS01800	COG1609	Transcriptional regulator
C0W57_RS01805	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C0W57_RS01810	COG1360	Flagellar Motor Protein
C0W57_RS01815	COG0123	including yeast histone deacetylase and acetoin utilization protein
C0W57_RS01820	COG0517	IMP dehydrogenase activity
C0W57_RS01825	COG0454	-acetyltransferase
C0W57_RS01830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C0W57_RS01855	COG1378	Sugar-specific transcriptional regulator TrmB
C0W57_RS01860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C0W57_RS01875	COG0693	protein deglycase activity
C0W57_RS01885	COG1017	nitric oxide dioxygenase activity
C0W57_RS01885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C0W57_RS01925	COG1012	belongs to the aldehyde dehydrogenase family
C0W57_RS01940	COG2203	Gaf domain
C0W57_RS01940	COG2199	diguanylate cyclase activity
C0W57_RS01945	COG1956	GAF domain-containing protein
C0W57_RS01950	COG1309	transcriptional regulator
C0W57_RS01955	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C0W57_RS01965	COG1114	Component of the transport system for branched-chain amino acids
C0W57_RS01970	COG1104	cysteine desulfurase activity
C0W57_RS01985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C0W57_RS01990	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C0W57_RS01995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C0W57_RS02000	COG0616	signal peptide processing
C0W57_RS02005	COG1714	RDD family
C0W57_RS02015	COG3874	Sporulation protein YtfJ
C0W57_RS02020	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C0W57_RS02025	COG0827	DNA restriction-modification system
C0W57_RS02035	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0W57_RS02050	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS02060	COG4109	DRTGG domain
C0W57_RS02070	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C0W57_RS02090	COG0587	DNA-directed DNA polymerase activity
C0W57_RS02095	COG0281	malic enzyme
C0W57_RS02115	COG0469	pyruvate kinase activity
C0W57_RS02120	COG3030	protein affecting phage T7 exclusion by the F plasmid
C0W57_RS02125	COG0628	permease
C0W57_RS02150	COG0457	Tetratricopeptide repeat
C0W57_RS02155	COG0372	Belongs to the citrate synthase family
C0W57_RS02160	COG0538	isocitrate dehydrogenase activity
C0W57_RS02170	COG0745	RESPONSE REGULATOR receiver
C0W57_RS02175	COG5002	protein histidine kinase activity
C0W57_RS02180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0W57_RS02180	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0W57_RS02185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C0W57_RS02190	COG1971	Probably functions as a manganese efflux pump
C0W57_RS02195	COG0237	dephospho-CoA kinase activity
C0W57_RS02200	COG0656	L-ascorbic acid biosynthetic process
C0W57_RS02205	COG2814	Major facilitator Superfamily
C0W57_RS02210	COG1733	regulation of RNA biosynthetic process
C0W57_RS02215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C0W57_RS02230	COG3611	Membrane attachment protein
C0W57_RS02235	COG1484	DNA-dependent DNA replication
C0W57_RS02240	COG0398	Pfam SNARE associated Golgi protein
C0W57_RS02255	COG1011	Hydrolase
C0W57_RS02260	COG3275	phosphorelay sensor kinase activity
C0W57_RS02265	COG3279	Response regulator of the LytR AlgR family
C0W57_RS02270	COG1380	Effector of murein hydrolase LrgA
C0W57_RS02275	COG1346	cytolysis
C0W57_RS02280	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C0W57_RS02295	COG3326	Membrane
C0W57_RS02305	COG1363	Peptidase, m42
C0W57_RS02310	COG3507	Belongs to the glycosyl hydrolase 43 family
C0W57_RS02315	COG2160	L-arabinose isomerase activity
C0W57_RS02320	COG1069	ribulokinase activity
C0W57_RS02325	COG0235	Class ii aldolase
C0W57_RS02330	COG0647	UMP catabolic process
C0W57_RS02340	COG1653	transport
C0W57_RS02345	COG1175	transmembrane transport
C0W57_RS02355	COG3534	alpha-L-arabinofuranosidase
C0W57_RS02360	COG1966	Carbon starvation protein
C0W57_RS02365	COG0247	lactate metabolic process
C0W57_RS02370	COG0277	FAD linked oxidase domain protein
C0W57_RS02375	COG3835	regulator
C0W57_RS02385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0W57_RS02390	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C0W57_RS02395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0W57_RS02395	COG0072	phenylalanine-tRNA ligase activity
C0W57_RS02410	COG1286	toxin biosynthetic process
C0W57_RS02415	COG1796	DNA polymerase
C0W57_RS02415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C0W57_RS02425	COG3766	membrane
C0W57_RS02435	COG0318	PFAM AMP-dependent synthetase and ligase
C0W57_RS02440	COG1309	transcriptional regulator
C0W57_RS02445	COG1024	Enoyl-CoA hydratase
C0W57_RS02450	COG2086	electron transfer activity
C0W57_RS02455	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C0W57_RS02460	COG3534	alpha-L-arabinofuranosidase
C0W57_RS02465	COG3118	belongs to the thioredoxin family
C0W57_RS02480	COG0527	aspartate kinase activity
C0W57_RS02485	COG1719	4-vinyl reductase, 4VR
C0W57_RS02490	COG2009	succinate dehydrogenase
C0W57_RS02495	COG1053	succinate dehydrogenase
C0W57_RS02500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C0W57_RS02505	COG0824	Thioesterase
C0W57_RS02510	COG2197	response regulator
C0W57_RS02515	COG2856	Zn peptidase
C0W57_RS02525	COG3620	sequence-specific DNA binding
C0W57_RS02535	COG3617	BRO family, N-terminal domain
C0W57_RS02565	COG5377	YqaJ viral recombinase family
C0W57_RS02570	COG3723	Recombinational DNA repair protein, rece pathway
C0W57_RS02580	COG1484	DNA-dependent DNA replication
C0W57_RS02670	COG3677	Transposase
C0W57_RS02680	COG5484	DNA packaging
C0W57_RS02755	COG3953	SLT domain
C0W57_RS02755	COG5280	Phage tail tape measure protein TP901
C0W57_RS02840	COG5444	nuclease activity
C0W57_RS02845	COG0457	Tetratricopeptide repeat
C0W57_RS02870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C0W57_RS02875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C0W57_RS02880	COG2197	response regulator
C0W57_RS02885	COG1846	Transcriptional regulator
C0W57_RS02895	COG5401	PFAM Sporulation and spore germination
C0W57_RS02910	COG0622	Phosphoesterase
C0W57_RS02940	COG0440	acetolactate synthase activity
C0W57_RS02955	COG0473	3-isopropylmalate dehydrogenase activity
C0W57_RS02970	COG0457	Tetratricopeptide repeat
C0W57_RS02970	COG1477	protein flavinylation
C0W57_RS02990	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C0W57_RS03010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0W57_RS03020	COG1587	Uroporphyrinogen-III synthase
C0W57_RS03025	COG0113	porphobilinogen synthase activity
C0W57_RS03035	COG1388	LysM domain
C0W57_RS03040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C0W57_RS03050	COG0525	valine-tRNA ligase activity
C0W57_RS03055	COG0285	dihydrofolate synthase activity
C0W57_RS03060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C0W57_RS03080	COG1077	Cell shape determining protein MreB Mrl
C0W57_RS03090	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C0W57_RS03100	COG2894	cell division
C0W57_RS03105	COG0739	heme binding
C0W57_RS03110	COG1994	Peptidase M50
C0W57_RS03120	COG2868	ribosomal protein
C0W57_RS03125	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C0W57_RS03130	COG3290	protein histidine kinase activity
C0W57_RS03145	COG0077	Prephenate dehydratase
C0W57_RS03150	COG1827	regulation of RNA biosynthetic process
C0W57_RS03155	COG1104	cysteine desulfurase activity
C0W57_RS03160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C0W57_RS03165	COG0157	Belongs to the NadC ModD family
C0W57_RS03175	COG1388	LysM domain
C0W57_RS03220	COG1862	Preprotein translocase
C0W57_RS03230	COG2323	membrane
C0W57_RS03245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0W57_RS03245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0W57_RS03250	COG0490	domain, Protein
C0W57_RS03255	COG5416	Lipopolysaccharide assembly protein A domain
C0W57_RS03260	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C0W57_RS03260	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C0W57_RS03270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C0W57_RS03280	COG4991	sh3 domain protein
C0W57_RS03280	COG3103	Sh3 type 3 domain protein
C0W57_RS03280	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0W57_RS03300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C0W57_RS03305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C0W57_RS03310	COG1959	2 iron, 2 sulfur cluster binding
C0W57_RS03315	COG1104	cysteine desulfurase activity
C0W57_RS03325	COG0457	Tetratricopeptide repeat
C0W57_RS03330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C0W57_RS03335	COG3881	PFAM PRC-barrel domain
C0W57_RS03350	COG0765	amino acid transport
C0W57_RS03355	COG0765	amino acid transport
C0W57_RS03360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0W57_RS03365	COG1126	abc transporter atp-binding protein
C0W57_RS03370	COG0628	permease
C0W57_RS03380	COG4472	Bacterial protein of unknown function (DUF965)
C0W57_RS03395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C0W57_RS03400	COG4122	O-methyltransferase activity
C0W57_RS03405	COG0826	peptidase U32
C0W57_RS03410	COG0826	peptidase U32
C0W57_RS03425	COG0768	penicillin binding
C0W57_RS03450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C0W57_RS03455	COG0626	cystathionine gamma-synthase activity
C0W57_RS03465	COG2427	Protein of unknown function (DUF1641)
C0W57_RS03470	COG3383	formate dehydrogenase (NAD+) activity
C0W57_RS03475	COG5609	conserved protein (DUF2294)
C0W57_RS03480	COG2116	formate transmembrane transporter activity
C0W57_RS03495	COG2226	methyltransferase
C0W57_RS03500	COG1309	transcriptional regulator
C0W57_RS03505	COG2124	cytochrome p450
C0W57_RS03505	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C0W57_RS03510	COG2814	Major facilitator Superfamily
C0W57_RS03515	COG0583	DNA-binding transcription factor activity
C0W57_RS03520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C0W57_RS03530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0W57_RS03530	COG3711	transcriptional antiterminator
C0W57_RS03535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0W57_RS03535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0W57_RS03535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0W57_RS03540	COG1482	cell wall glycoprotein biosynthetic process
C0W57_RS03550	COG0561	phosphatase activity
C0W57_RS03555	COG0561	phosphatase activity
C0W57_RS03565	COG2318	DinB family
C0W57_RS03570	COG0456	acetyltransferase
C0W57_RS03605	COG5444	nuclease activity
C0W57_RS03620	COG2814	Major facilitator Superfamily
C0W57_RS03630	COG0563	adenylate kinase activity
C0W57_RS03635	COG0454	-acetyltransferase
C0W57_RS03640	COG2311	Membrane
C0W57_RS03645	COG0745	RESPONSE REGULATOR receiver
C0W57_RS03650	COG5002	protein histidine kinase activity
C0W57_RS03650	COG0642	Histidine kinase
C0W57_RS03665	COG0583	DNA-binding transcription factor activity
C0W57_RS03670	COG3708	Transcriptional regulator
C0W57_RS03670	COG2207	Transcriptional regulator
C0W57_RS03685	COG4282	regulation of fungal-type cell wall biogenesis
C0W57_RS03690	COG5444	nuclease activity
C0W57_RS03740	COG0398	Pfam SNARE associated Golgi protein
C0W57_RS03750	COG2755	lipolytic protein G-D-S-L family
C0W57_RS03760	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C0W57_RS03765	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C0W57_RS03770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C0W57_RS03775	COG1534	Rna-binding protein
C0W57_RS03785	COG1713	HD superfamily hydrolase involved in NAD metabolism
C0W57_RS03790	COG0799	negative regulation of ribosome biogenesis
C0W57_RS03795	COG2226	methyltransferase
C0W57_RS03800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C0W57_RS03805	COG1555	photosystem II stabilization
C0W57_RS03805	COG1596	polysaccharide export
C0W57_RS03810	COG2131	deaminase
C0W57_RS03815	COG0658	competence protein
C0W57_RS03815	COG2333	competence protein COMEC
C0W57_RS03825	COG1466	dna polymerase III delta subunit
C0W57_RS03840	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0W57_RS03855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C0W57_RS03885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C0W57_RS03890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C0W57_RS03895	COG1283	sodium-dependent phosphate transmembrane transporter activity
C0W57_RS03905	COG1610	YqeY-like protein
C0W57_RS03910	COG1030	water channel activity
C0W57_RS03915	COG4864	UPF0365 protein
C0W57_RS03930	COG0561	phosphatase activity
C0W57_RS03935	COG1702	phosphate starvation-inducible protein PhoH
C0W57_RS03940	COG1480	7TM receptor with intracellular HD hydrolase
C0W57_RS03950	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C0W57_RS03955	COG0295	cytidine deaminase activity
C0W57_RS03960	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C0W57_RS03980	COG0751	glycine-tRNA ligase activity
C0W57_RS03985	COG0517	IMP dehydrogenase activity
C0W57_RS04000	COG0358	DNA primase activity
C0W57_RS04005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C0W57_RS04010	COG2010	Cytochrome c
C0W57_RS04015	COG2384	SAM-dependent methyltransferase
C0W57_RS04020	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C0W57_RS04035	COG0513	Belongs to the DEAD box helicase family
C0W57_RS04055	COG0735	belongs to the Fur family
C0W57_RS04060	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C0W57_RS04065	COG4709	membrane
C0W57_RS04080	COG1388	LysM domain
C0W57_RS04085	COG5521	maltodextrose utilization protein MalA
C0W57_RS04090	COG2839	Protein conserved in bacteria
C0W57_RS04095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C0W57_RS04100	COG0477	Major facilitator Superfamily
C0W57_RS04105	COG0768	penicillin binding
C0W57_RS04110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C0W57_RS04115	COG0573	inorganic phosphate transmembrane transporter activity
C0W57_RS04120	COG0581	inorganic phosphate transmembrane transporter activity
C0W57_RS04125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C0W57_RS04130	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C0W57_RS04135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C0W57_RS04150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C0W57_RS04160	COG1757	Na H antiporter
C0W57_RS04165	COG4483	Protein conserved in bacteria
C0W57_RS04170	COG1940	carbohydrate kinase activity
C0W57_RS04175	COG2866	Carboxypeptidase
C0W57_RS04185	COG0011	TIGRFAM Protein of
C0W57_RS04195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0W57_RS04205	COG1393	Belongs to the ArsC family
C0W57_RS04215	COG1366	Belongs to the anti-sigma-factor antagonist family
C0W57_RS04220	COG1253	flavin adenine dinucleotide binding
C0W57_RS04225	COG0598	Magnesium transport protein CorA
C0W57_RS04230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C0W57_RS04235	COG1459	type II secretion system
C0W57_RS04240	COG4537	Required for transformation and DNA binding
C0W57_RS04245	COG4970	Tfp pilus assembly protein FimT
C0W57_RS04255	COG4940	Competence protein ComGF
C0W57_RS04280	COG0681	Belongs to the peptidase S26 family
C0W57_RS04290	COG1396	sequence-specific DNA binding
C0W57_RS04305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C0W57_RS04325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0W57_RS04340	COG1752	Esterase of the alpha-beta hydrolase superfamily
C0W57_RS04350	COG3872	metal-dependent enzyme
C0W57_RS04360	COG0006	proline dipeptidase activity
C0W57_RS04375	COG3854	ATPases associated with a variety of cellular activities
C0W57_RS04415	COG0511	ligase activity, forming carbon-carbon bonds
C0W57_RS04420	COG0439	Biotin carboxylase
C0W57_RS04425	COG1302	Protein conserved in bacteria
C0W57_RS04440	COG1570	exodeoxyribonuclease VII activity
C0W57_RS04450	COG0142	geranyltranstransferase activity
C0W57_RS04460	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C0W57_RS04470	COG0497	DNA recombination
C0W57_RS04475	COG0750	zinc metalloprotease
C0W57_RS04480	COG0745	RESPONSE REGULATOR receiver
C0W57_RS04485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C0W57_RS04500	COG1902	pentaerythritol trinitrate reductase activity
C0W57_RS04520	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0W57_RS04525	COG0584	glycerophosphoryl diester phosphodiesterase
C0W57_RS04530	COG0183	Belongs to the thiolase family
C0W57_RS04535	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0W57_RS04540	COG1960	acyl-CoA dehydrogenase activity
C0W57_RS04545	COG0372	Belongs to the citrate synthase family
C0W57_RS04550	COG2079	MmgE PrpD family protein
C0W57_RS04555	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C0W57_RS04565	COG3290	protein histidine kinase activity
C0W57_RS04565	COG3829	transcription factor binding
C0W57_RS04570	COG0280	phosphate acetyltransferase
C0W57_RS04575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C0W57_RS04580	COG3426	butyrate kinase activity
C0W57_RS04585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0W57_RS04590	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C0W57_RS04595	COG0022	dehydrogenase e1 component
C0W57_RS04600	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0W57_RS04605	COG1597	lipid kinase activity
C0W57_RS04615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0W57_RS04620	COG0765	amino acid transport
C0W57_RS04625	COG1126	abc transporter atp-binding protein
C0W57_RS04630	COG4129	membrane
C0W57_RS04635	COG1376	ErfK ybiS ycfS ynhG family protein
C0W57_RS04640	COG0346	lactoylglutathione lyase activity
C0W57_RS04645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0W57_RS04650	COG2195	Cleaves the N-terminal amino acid of tripeptides
C0W57_RS04655	COG0706	membrane insertase activity
C0W57_RS04670	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C0W57_RS04675	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C0W57_RS04690	COG0596	Alpha beta hydrolase
C0W57_RS04715	COG0250	Participates in transcription elongation, termination and antitermination
C0W57_RS04720	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C0W57_RS04720	COG2070	2-Nitropropane dioxygenase
C0W57_RS04735	COG0318	PFAM AMP-dependent synthetase and ligase
C0W57_RS04740	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS04745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS04745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0W57_RS04745	COG3321	synthase
C0W57_RS04745	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS04745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0W57_RS04750	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS04750	COG0318	PFAM AMP-dependent synthetase and ligase
C0W57_RS04750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS04750	COG0300	oxidoreductase activity
C0W57_RS04750	COG3321	synthase
C0W57_RS04755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0W57_RS04755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS04755	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS04755	COG3321	synthase
C0W57_RS04755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0W57_RS04760	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS04760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS04760	COG0318	PFAM AMP-dependent synthetase and ligase
C0W57_RS04760	COG0300	oxidoreductase activity
C0W57_RS04760	COG3321	synthase
C0W57_RS04765	COG0300	oxidoreductase activity
C0W57_RS04765	COG0318	PFAM AMP-dependent synthetase and ligase
C0W57_RS04765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS04765	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS04765	COG3321	synthase
C0W57_RS04775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0W57_RS04775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS04775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0W57_RS04775	COG3321	synthase
C0W57_RS04775	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS04780	COG2124	cytochrome p450
C0W57_RS04785	COG3425	synthase
C0W57_RS04790	COG1024	Enoyl-CoA hydratase
C0W57_RS04795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C0W57_RS04800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0W57_RS04805	COG0300	oxidoreductase activity
C0W57_RS04810	COG3048	D-serine ammonia-lyase activity
C0W57_RS04820	COG0346	lactoylglutathione lyase activity
C0W57_RS04830	COG0628	permease
C0W57_RS04845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C0W57_RS04850	COG0456	acetyltransferase
C0W57_RS04855	COG2329	Antibiotic biosynthesis monooxygenase
C0W57_RS04860	COG0456	acetyltransferase
C0W57_RS04860	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C0W57_RS04865	COG4918	Iron-sulphur cluster biosynthesis
C0W57_RS04875	COG1073	alpha beta
C0W57_RS04885	COG0667	Aldo Keto reductase
C0W57_RS04895	COG0494	nUDIX hydrolase
C0W57_RS04900	COG1379	DNA repair
C0W57_RS04905	COG1396	sequence-specific DNA binding
C0W57_RS04910	COG0252	asparaginase activity
C0W57_RS04915	COG1027	Aspartate ammonia-lyase
C0W57_RS04920	COG1757	Na H antiporter
C0W57_RS04925	COG0281	malic enzyme
C0W57_RS04940	COG1300	Membrane
C0W57_RS04945	COG0735	belongs to the Fur family
C0W57_RS04955	COG4974	Belongs to the 'phage' integrase family
C0W57_RS04960	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C0W57_RS04965	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C0W57_RS04975	COG1366	Belongs to the anti-sigma-factor antagonist family
C0W57_RS04985	COG1191	sigma factor activity
C0W57_RS05005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0W57_RS05020	COG0697	spore germination
C0W57_RS05025	COG0019	diaminopimelate decarboxylase activity
C0W57_RS05030	COG4086	secreted protein
C0W57_RS05035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C0W57_RS05045	COG0681	Belongs to the peptidase S26 family
C0W57_RS05055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0W57_RS05055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0W57_RS05060	COG0307	riboflavin synthase, alpha
C0W57_RS05075	COG0456	acetyltransferase
C0W57_RS05085	COG1547	Domain of unknown function (DUF309)
C0W57_RS05110	COG1686	Belongs to the peptidase S11 family
C0W57_RS05115	COG2715	membrane protein required for spore maturation
C0W57_RS05120	COG0700	Nucleoside recognition
C0W57_RS05125	COG1187	pseudouridine synthase activity
C0W57_RS05130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0W57_RS05135	COG1333	cytochrome c biogenesis protein
C0W57_RS05140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0W57_RS05145	COG0745	RESPONSE REGULATOR receiver
C0W57_RS05150	COG5002	protein histidine kinase activity
C0W57_RS05155	COG1595	DNA-templated transcription, initiation
C0W57_RS05165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C0W57_RS05170	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C0W57_RS05175	COG1141	Ferredoxin
C0W57_RS05180	COG4955	Helix-turn-helix domain
C0W57_RS05185	COG0514	ATP-dependent DNA helicase (RecQ)
C0W57_RS05190	COG1266	CAAX protease self-immunity
C0W57_RS05195	COG1388	LysM domain
C0W57_RS05205	COG1408	metallophosphoesterase
C0W57_RS05210	COG4862	establishment of competence for transformation
C0W57_RS05215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C0W57_RS05220	COG0492	ferredoxin-NADP+ reductase activity
C0W57_RS05225	COG2339	peptidase activity
C0W57_RS05230	COG3409	Peptidoglycan-binding domain 1 protein
C0W57_RS05230	COG3773	Cell wall hydrolase
C0W57_RS05235	COG2959	enzyme of heme biosynthesis
C0W57_RS05240	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C0W57_RS05250	COG0539	negative regulation of cytoplasmic translation
C0W57_RS05290	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C0W57_RS05295	COG0776	regulation of translation
C0W57_RS05310	COG0142	geranyltranstransferase activity
C0W57_RS05320	COG0142	geranyltranstransferase activity
C0W57_RS05325	COG0105	UTP biosynthetic process
C0W57_RS05330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C0W57_RS05345	COG4401	Chorismate mutase type I
C0W57_RS05350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C0W57_RS05385	COG0287	Prephenate dehydrogenase
C0W57_RS05395	COG0457	Tetratricopeptide repeat
C0W57_RS05410	COG0723	plastoquinol--plastocyanin reductase activity
C0W57_RS05415	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C0W57_RS05420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C0W57_RS05420	COG2010	Cytochrome c
C0W57_RS05425	COG4347	Protein of unknown function (DUF1405)
C0W57_RS05435	COG2140	Oxalate decarboxylase
C0W57_RS05440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0W57_RS05445	COG1694	Mazg nucleotide pyrophosphohydrolase
C0W57_RS05460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C0W57_RS05465	COG0438	transferase activity, transferring glycosyl groups
C0W57_RS05495	COG1199	ATP-dependent helicase activity
C0W57_RS05495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0W57_RS05505	COG5353	protein conserved in bacteria
C0W57_RS05510	COG0436	Aminotransferase
C0W57_RS05520	COG3935	DnaD domain protein
C0W57_RS05525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C0W57_RS05535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0W57_RS05535	COG4499	WXG100 protein secretion system (Wss), protein YukC
C0W57_RS05575	COG0071	Belongs to the small heat shock protein (HSP20) family
C0W57_RS05585	COG1205	dead DEAH box helicase
C0W57_RS05585	COG1111	helicase
C0W57_RS05590	COG3359	exonuclease
C0W57_RS05615	COG0116	Belongs to the methyltransferase superfamily
C0W57_RS05630	COG1199	ATP-dependent helicase activity
C0W57_RS05635	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C0W57_RS05645	COG2233	PERMEase
C0W57_RS05655	COG1335	isochorismatase
C0W57_RS05685	COG3424	synthase
C0W57_RS05690	COG1755	Isoprenylcysteine carboxyl methyltransferase
C0W57_RS05700	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C0W57_RS05715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0W57_RS05725	COG0328	RNA-DNA hybrid ribonuclease activity
C0W57_RS05730	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C0W57_RS05735	COG0328	RNA-DNA hybrid ribonuclease activity
C0W57_RS05755	COG1278	Cold shock
C0W57_RS05760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C0W57_RS05770	COG0386	Belongs to the glutathione peroxidase family
C0W57_RS05775	COG1418	mRNA catabolic process
C0W57_RS05780	COG1413	lyase activity
C0W57_RS05795	COG2136	Putative SAM-dependent methyltransferase
C0W57_RS05795	COG2521	methyltransferase
C0W57_RS05810	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C0W57_RS05815	COG0204	Acyl-transferase
C0W57_RS05825	COG1272	protein, Hemolysin III
C0W57_RS05830	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C0W57_RS05835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C0W57_RS05845	COG1999	signal sequence binding
C0W57_RS05850	COG2755	lipolytic protein G-D-S-L family
C0W57_RS05855	COG4698	Protein conserved in bacteria
C0W57_RS05860	COG1846	Transcriptional regulator
C0W57_RS05880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C0W57_RS05900	COG1525	nuclease
C0W57_RS05905	COG4282	regulation of fungal-type cell wall biogenesis
C0W57_RS05910	COG5444	nuclease activity
C0W57_RS05935	COG0730	response to heat
C0W57_RS05945	COG4585	Histidine kinase
C0W57_RS05950	COG2197	response regulator
C0W57_RS05975	COG0457	Tetratricopeptide repeat
C0W57_RS06005	COG3655	Transcriptional regulator
C0W57_RS06040	COG0457	Tetratricopeptide repeat
C0W57_RS06045	COG1388	LysM domain
C0W57_RS06070	COG3331	DNA recombination
C0W57_RS06080	COG1086	Polysaccharide biosynthesis protein
C0W57_RS06090	COG4641	Protein conserved in bacteria
C0W57_RS06105	COG0463	Glycosyl transferase, family 2
C0W57_RS06110	COG0456	acetyltransferase
C0W57_RS06120	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C0W57_RS06130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C0W57_RS06135	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C0W57_RS06140	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C0W57_RS06145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0W57_RS06150	COG0456	acetyltransferase
C0W57_RS06155	COG1509	lysine 2,3-aminomutase activity
C0W57_RS06185	COG0671	phosphoesterase, PA-phosphatase related
C0W57_RS06210	COG1876	peptidase activity
C0W57_RS06220	COG2226	methyltransferase
C0W57_RS06225	COG0793	Belongs to the peptidase S41A family
C0W57_RS06225	COG3409	Peptidoglycan-binding domain 1 protein
C0W57_RS06230	COG2188	Transcriptional regulator
C0W57_RS06235	COG2723	6-phospho-beta-galactosidase activity
C0W57_RS06245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C0W57_RS06255	COG0346	lactoylglutathione lyase activity
C0W57_RS06260	COG0400	carboxylic ester hydrolase activity
C0W57_RS06265	COG0778	Nitroreductase
C0W57_RS06270	COG1733	regulation of RNA biosynthetic process
C0W57_RS06280	COG1942	4-Oxalocrotonate Tautomerase
C0W57_RS06295	COG2962	Rard protein
C0W57_RS06305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C0W57_RS06310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C0W57_RS06315	COG1366	Belongs to the anti-sigma-factor antagonist family
C0W57_RS06320	COG0534	Mate efflux family protein
C0W57_RS06325	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C0W57_RS06330	COG1819	glycosyl
C0W57_RS06335	COG0791	NLP P60 protein
C0W57_RS06335	COG1388	LysM domain
C0W57_RS06340	COG2032	superoxide dismutase activity
C0W57_RS06345	COG0714	Associated with various cellular activities
C0W57_RS06350	COG4548	von Willebrand factor, type A
C0W57_RS06360	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0W57_RS06365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0W57_RS06370	COG0385	Bile acid
C0W57_RS06375	COG0733	neurotransmitter:sodium symporter activity
C0W57_RS06380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C0W57_RS06385	COG1657	PFAM Prenyltransferase squalene oxidase
C0W57_RS06390	COG1012	belongs to the aldehyde dehydrogenase family
C0W57_RS06420	COG0071	Belongs to the small heat shock protein (HSP20) family
C0W57_RS06435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C0W57_RS06440	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C0W57_RS06450	COG0514	ATP-dependent DNA helicase (RecQ)
C0W57_RS06455	COG1388	LysM domain
C0W57_RS06455	COG3584	3D domain protein
C0W57_RS06465	COG1619	proteins homologs of microcin C7 resistance protein MccF
C0W57_RS06480	COG2322	membrane
C0W57_RS06485	COG0741	lytic transglycosylase activity
C0W57_RS06490	COG0640	Transcriptional regulator
C0W57_RS06500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0W57_RS06505	COG1309	transcriptional regulator
C0W57_RS06510	COG0662	Cupin 2, conserved barrel domain protein
C0W57_RS06510	COG2207	Transcriptional regulator
C0W57_RS06515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0W57_RS06520	COG5444	nuclease activity
C0W57_RS06565	COG3397	chitin binding
C0W57_RS06580	COG5434	Belongs to the glycosyl hydrolase 28 family
C0W57_RS06590	COG0756	dUTP diphosphatase activity
C0W57_RS06600	COG4195	phage-related replication protein
C0W57_RS06630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C0W57_RS06640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C0W57_RS06660	COG0785	Cytochrome C biogenesis protein
C0W57_RS06665	COG2201	protein-glutamate methylesterase activity
C0W57_RS06670	COG4846	Membrane protein involved in cytochrome C biogenesis
C0W57_RS06680	COG0071	Belongs to the small heat shock protein (HSP20) family
C0W57_RS06695	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C0W57_RS06700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0W57_RS06720	COG0824	Thioesterase
C0W57_RS06730	COG4841	protein insertion into membrane
C0W57_RS06740	COG1832	CoA-binding protein
C0W57_RS06745	COG0187	DNA topoisomerase II activity
C0W57_RS06750	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C0W57_RS06760	COG1115	amino acid carrier protein
C0W57_RS06770	COG1063	alcohol dehydrogenase
C0W57_RS06775	COG0800	Aldolase
C0W57_RS06780	COG1312	Catalyzes the dehydration of D-mannonate
C0W57_RS06785	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS06790	COG1609	Transcriptional regulator
C0W57_RS06795	COG2271	Major facilitator Superfamily
C0W57_RS06820	COG0577	efflux transmembrane transporter activity
C0W57_RS06820	COG1136	(ABC) transporter
C0W57_RS06850	COG0745	RESPONSE REGULATOR receiver
C0W57_RS06860	COG3507	Belongs to the glycosyl hydrolase 43 family
C0W57_RS06885	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS06890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C0W57_RS06895	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C0W57_RS06900	COG2610	gluconate transmembrane transporter activity
C0W57_RS06905	COG2124	cytochrome p450
C0W57_RS06925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C0W57_RS06935	COG2246	polysaccharide biosynthetic process
C0W57_RS06940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C0W57_RS06945	COG0586	Pfam SNARE associated Golgi protein
C0W57_RS06950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0W57_RS06955	COG1024	Enoyl-CoA hydratase
C0W57_RS06960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C0W57_RS06965	COG0511	ligase activity, forming carbon-carbon bonds
C0W57_RS06970	COG0439	Biotin carboxylase
C0W57_RS06975	COG0318	PFAM AMP-dependent synthetase and ligase
C0W57_RS06980	COG1960	acyl-CoA dehydrogenase activity
C0W57_RS06985	COG1649	PFAM Uncharacterised BCR, COG1649
C0W57_RS07000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS07005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS07010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS07015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS07020	COG2027	D-alanyl-D-alanine carboxypeptidase
C0W57_RS07025	COG2017	converts alpha-aldose to the beta-anomer
C0W57_RS07030	COG0534	Mate efflux family protein
C0W57_RS07045	COG0582	viral genome integration into host DNA
C0W57_RS07050	COG0166	Belongs to the GPI family
C0W57_RS07055	COG0405	Gamma-glutamyltransferase
C0W57_RS07060	COG2814	Major facilitator Superfamily
C0W57_RS07065	COG0640	Transcriptional regulator
C0W57_RS07070	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C0W57_RS07080	COG0604	alcohol dehydrogenase
C0W57_RS07090	COG0493	'glutamate synthase
C0W57_RS07095	COG0070	glutamate synthase
C0W57_RS07095	COG0069	glutamate synthase activity
C0W57_RS07095	COG0067	glutamate synthase
C0W57_RS07100	COG0583	DNA-binding transcription factor activity
C0W57_RS07105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C0W57_RS07125	COG0300	oxidoreductase activity
C0W57_RS07130	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C0W57_RS07140	COG2814	Major facilitator Superfamily
C0W57_RS07145	COG1070	Carbohydrate kinase
C0W57_RS07150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C0W57_RS07155	COG0243	molybdopterin cofactor binding
C0W57_RS07185	COG5444	nuclease activity
C0W57_RS07190	COG0456	acetyltransferase
C0W57_RS07220	COG1064	alcohol dehydrogenase
C0W57_RS07225	COG2318	DinB family
C0W57_RS07230	COG2378	regulation of single-species biofilm formation
C0W57_RS07255	COG0574	Belongs to the PEP-utilizing enzyme family
C0W57_RS07255	COG3848	Pyruvate phosphate dikinase
C0W57_RS07260	COG1070	Carbohydrate kinase
C0W57_RS07275	COG3507	Belongs to the glycosyl hydrolase 43 family
C0W57_RS07280	COG2211	Major facilitator Superfamily
C0W57_RS07315	COG0174	glutamine synthetase
C0W57_RS07320	COG0789	Transcriptional regulator
C0W57_RS07325	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C0W57_RS07330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C0W57_RS07335	COG0464	growth
C0W57_RS07345	COG3331	DNA recombination
C0W57_RS07375	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C0W57_RS07415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C0W57_RS07420	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C0W57_RS07455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0W57_RS07485	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0W57_RS07490	COG1780	Probably involved in ribonucleotide reductase function
C0W57_RS07595	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C0W57_RS07605	COG3584	3D domain protein
C0W57_RS07645	COG2404	hydrolase activity, acting on ester bonds
C0W57_RS07670	COG3420	alginic acid biosynthetic process
C0W57_RS07670	COG5434	Belongs to the glycosyl hydrolase 28 family
C0W57_RS07675	COG4195	phage-related replication protein
C0W57_RS07690	COG2135	peptidase activity
C0W57_RS07695	COG1793	dna ligase
C0W57_RS07790	COG3655	Transcriptional regulator
C0W57_RS07885	COG3655	Transcriptional regulator
C0W57_RS07890	COG3655	Transcriptional regulator
C0W57_RS07985	COG0776	regulation of translation
C0W57_RS08130	COG4974	Belongs to the 'phage' integrase family
C0W57_RS08165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C0W57_RS08205	COG5444	nuclease activity
C0W57_RS08210	COG1525	nuclease
C0W57_RS08230	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0W57_RS08240	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0W57_RS08245	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0W57_RS08285	COG2076	Multidrug Resistance protein
C0W57_RS08295	COG1764	response to oxidative stress
C0W57_RS08300	COG4195	phage-related replication protein
C0W57_RS08310	COG1404	Belongs to the peptidase S8 family
C0W57_RS08320	COG3619	membrane
C0W57_RS08325	COG3209	COG3209 Rhs family protein
C0W57_RS08330	COG2124	cytochrome p450
C0W57_RS08335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0W57_RS08335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C0W57_RS08335	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C0W57_RS08335	COG3321	synthase
C0W57_RS08340	COG4221	oxidoreductase activity
C0W57_RS08340	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS08340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS08340	COG3321	synthase
C0W57_RS08345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0W57_RS08345	COG3321	synthase
C0W57_RS08345	COG3321	synthase
C0W57_RS08345	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS08345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0W57_RS08345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0W57_RS08345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0W57_RS08345	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS08345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS08345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS08350	COG3321	synthase
C0W57_RS08350	COG4221	oxidoreductase activity
C0W57_RS08350	COG0300	oxidoreductase activity
C0W57_RS08350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0W57_RS08355	COG0300	oxidoreductase activity
C0W57_RS08355	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS08355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS08355	COG0318	PFAM AMP-dependent synthetase and ligase
C0W57_RS08355	COG3321	synthase
C0W57_RS08360	COG1024	Enoyl-CoA hydratase
C0W57_RS08365	COG1024	Enoyl-CoA hydratase
C0W57_RS08370	COG3425	synthase
C0W57_RS08375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0W57_RS08410	COG5444	nuclease activity
C0W57_RS08440	COG0582	viral genome integration into host DNA
C0W57_RS08465	COG4550	Control of competence regulator ComK, YlbF/YmcA
C0W57_RS08485	COG2359	stage V sporulation protein S
C0W57_RS08490	COG1692	metallophosphoesterase
C0W57_RS08500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C0W57_RS08515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C0W57_RS08520	COG1426	Protein conserved in bacteria
C0W57_RS08535	COG0300	oxidoreductase activity
C0W57_RS08540	COG0612	Peptidase, M16
C0W57_RS08545	COG0612	Peptidase, M16
C0W57_RS08550	COG1033	growth of symbiont in host cell
C0W57_RS08550	COG2409	Drug exporters of the RND superfamily
C0W57_RS08555	COG1846	Transcriptional regulator
C0W57_RS08560	COG2814	Major facilitator Superfamily
C0W57_RS08565	COG2188	Transcriptional regulator
C0W57_RS08570	COG1674	ftsk spoiiie
C0W57_RS08570	COG4980	gas vesicle protein
C0W57_RS08580	COG0740	serine-type endopeptidase activity
C0W57_RS08585	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C0W57_RS08595	COG0527	aspartate kinase activity
C0W57_RS08600	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C0W57_RS08605	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C0W57_RS08610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0W57_RS08615	COG1873	PFAM PRC-barrel domain
C0W57_RS08620	COG0612	Peptidase, M16
C0W57_RS08625	COG0726	polysaccharide deacetylase
C0W57_RS08640	COG0196	riboflavin kinase activity
C0W57_RS08655	COG1550	Protein conserved in bacteria
C0W57_RS08665	COG1358	cellular component organization or biogenesis
C0W57_RS08670	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C0W57_RS08675	COG0195	Participates in both transcription termination and antitermination
C0W57_RS08695	COG0750	zinc metalloprotease
C0W57_RS08705	COG4589	Belongs to the CDS family
C0W57_RS08710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C0W57_RS08740	COG1191	sigma factor activity
C0W57_RS08750	COG1776	CheC inhibitor of MCP methylation
C0W57_RS08755	COG0835	chemotaxis
C0W57_RS08760	COG0643	Histidine kinase
C0W57_RS08760	COG2198	Histidine kinase
C0W57_RS08765	COG2201	protein-glutamate methylesterase activity
C0W57_RS08770	COG0455	bacterial-type flagellum organization
C0W57_RS08775	COG1419	protein localization to endoplasmic reticulum
C0W57_RS08780	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C0W57_RS08785	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C0W57_RS08790	COG1684	flagellar biosynthetic protein fliR
C0W57_RS08795	COG1987	bacterial-type flagellum assembly
C0W57_RS08800	COG1338	Plays a role in the flagellum-specific transport system
C0W57_RS08805	COG3190	flagellar
C0W57_RS08810	COG2201	protein-glutamate methylesterase activity
C0W57_RS08815	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C0W57_RS08815	COG1776	CheC inhibitor of MCP methylation
C0W57_RS08820	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C0W57_RS08825	COG1580	Controls the rotational direction of flagella during chemotaxis
C0W57_RS08830	COG1582	Flagellar protein (FlbD)
C0W57_RS08835	COG4786	Flagellar basal body rod
C0W57_RS08840	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C0W57_RS08845	COG3144	bacterial-type flagellum assembly
C0W57_RS08850	COG3334	PFAM MgtE intracellular
C0W57_RS08855	COG2882	bacterial-type flagellum organization
C0W57_RS08860	COG1157	protein secretion by the type III secretion system
C0W57_RS08865	COG1317	bacterial-type flagellum organization
C0W57_RS08870	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C0W57_RS08875	COG1766	The M ring may be actively involved in energy transduction
C0W57_RS08880	COG1677	Flagellar hook-basal body complex protein FliE
C0W57_RS08885	COG1558	bacterial-type flagellum-dependent cell motility
C0W57_RS08890	COG1815	bacterial-type flagellum-dependent cell motility
C0W57_RS08910	COG4974	Belongs to the 'phage' integrase family
C0W57_RS08920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C0W57_RS08925	COG0758	DNA mediated transformation
C0W57_RS08930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C0W57_RS08940	COG2257	FlhB HrpN YscU SpaS Family
C0W57_RS08955	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C0W57_RS08980	COG1837	Belongs to the UPF0109 family
C0W57_RS08990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C0W57_RS09005	COG0552	protein localization to endoplasmic reticulum
C0W57_RS09025	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS09030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C0W57_RS09045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C0W57_RS09050	COG1760	l-serine dehydratase
C0W57_RS09055	COG1760	l-serine dehydratase
C0W57_RS09060	COG1461	Dihydroxyacetone kinase
C0W57_RS09065	COG1302	Protein conserved in bacteria
C0W57_RS09080	COG1564	THIamine pyrophosphokinase
C0W57_RS09085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C0W57_RS09095	COG2815	serine threonine protein kinase
C0W57_RS09095	COG0515	serine threonine protein kinase
C0W57_RS09100	COG0631	protein serine/threonine phosphatase activity
C0W57_RS09110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0W57_RS09110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C0W57_RS09120	COG0242	peptide deformylase activity
C0W57_RS09125	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C0W57_RS09130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C0W57_RS09140	COG0194	GDP metabolic process
C0W57_RS09150	COG1561	YicC-like family, N-terminal region
C0W57_RS09155	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C0W57_RS09170	COG1648	precorrin-2 dehydrogenase activity
C0W57_RS09175	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C0W57_RS09180	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0W57_RS09195	COG0306	phosphate transporter
C0W57_RS09205	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C0W57_RS09210	COG0284	orotidine-5'-phosphate decarboxylase activity
C0W57_RS09225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C0W57_RS09230	COG0505	Belongs to the CarA family
C0W57_RS09235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C0W57_RS09245	COG2233	PERMEase
C0W57_RS09255	COG0564	pseudouridine synthase activity
C0W57_RS09265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C0W57_RS09270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C0W57_RS09280	COG3599	regulation of cell shape
C0W57_RS09285	COG2302	S4 RNA-binding domain
C0W57_RS09290	COG0762	integral membrane protein
C0W57_RS09300	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C0W57_RS09305	COG1496	oxidoreductase activity
C0W57_RS09310	COG1873	PFAM PRC-barrel domain
C0W57_RS09315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0W57_RS09320	COG1119	ATPase activity
C0W57_RS09325	COG1191	sigma factor activity
C0W57_RS09330	COG1191	sigma factor activity
C0W57_RS09340	COG1404	Belongs to the peptidase S8 family
C0W57_RS09340	COG4412	M6 family metalloprotease domain protein
C0W57_RS09345	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C0W57_RS09350	COG0849	cell division
C0W57_RS09355	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C0W57_RS09370	COG0772	Belongs to the SEDS family
C0W57_RS09390	COG0768	penicillin binding
C0W57_RS09395	COG0768	penicillin binding
C0W57_RS09400	COG4839	cell division protein FtsL
C0W57_RS09420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C0W57_RS09440	COG1399	metal-binding, possibly nucleic acid-binding protein
C0W57_RS09455	COG3480	Lon protease (S16) C-terminal proteolytic domain
C0W57_RS09460	COG1752	Esterase of the alpha-beta hydrolase superfamily
C0W57_RS09465	COG3314	Sporulation integral membrane protein YlbJ
C0W57_RS09475	COG0742	ribosomal rna small subunit methyltransferase
C0W57_RS09490	COG3679	Belongs to the UPF0342 family
C0W57_RS09505	COG2340	Cysteine-rich secretory protein family
C0W57_RS09510	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C0W57_RS09520	COG3336	cytochrome c oxidase
C0W57_RS09525	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C0W57_RS09530	COG1845	cytochrome c oxidase, subunit III
C0W57_RS09535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C0W57_RS09540	COG2010	Cytochrome c
C0W57_RS09540	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C0W57_RS09555	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C0W57_RS09560	COG0772	Belongs to the SEDS family
C0W57_RS09570	COG2066	Belongs to the glutaminase family
C0W57_RS09575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C0W57_RS09580	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C0W57_RS09590	COG4896	Protein conserved in bacteria
C0W57_RS09600	COG1217	gtp-binding protein TYPA
C0W57_RS09625	COG3227	Zinc metalloprotease (Elastase)
C0W57_RS09635	COG0483	inositol monophosphate 1-phosphatase activity
C0W57_RS09660	COG1982	Orn Lys Arg decarboxylase major
C0W57_RS09675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0W57_RS09680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0W57_RS09685	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0W57_RS09690	COG0022	dehydrogenase e1 component
C0W57_RS09695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C0W57_RS09700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C0W57_RS09705	COG4221	oxidoreductase activity
C0W57_RS09705	COG3321	synthase
C0W57_RS09705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS09705	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS09715	COG3321	synthase
C0W57_RS09715	COG0300	oxidoreductase activity
C0W57_RS09715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0W57_RS09715	COG4221	oxidoreductase activity
C0W57_RS09720	COG0300	oxidoreductase activity
C0W57_RS09720	COG3321	synthase
C0W57_RS09720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0W57_RS09720	COG4221	oxidoreductase activity
C0W57_RS09725	COG4221	oxidoreductase activity
C0W57_RS09725	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS09725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS09725	COG3321	synthase
C0W57_RS09730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0W57_RS09730	COG0300	oxidoreductase activity
C0W57_RS09730	COG3321	synthase
C0W57_RS09730	COG4221	oxidoreductase activity
C0W57_RS09735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS09735	COG4221	oxidoreductase activity
C0W57_RS09735	COG3321	synthase
C0W57_RS09735	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS09750	COG0497	DNA recombination
C0W57_RS09760	COG0242	peptide deformylase activity
C0W57_RS09765	COG0561	phosphatase activity
C0W57_RS09775	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C0W57_RS09785	COG0569	domain protein
C0W57_RS09790	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C0W57_RS09790	COG2105	PFAM AIG2 family protein
C0W57_RS09795	COG3852	Histidine kinase
C0W57_RS09800	COG2002	toxin-antitoxin pair type II binding
C0W57_RS09810	COG1077	Cell shape determining protein MreB Mrl
C0W57_RS09820	COG2309	aminopeptidase activity
C0W57_RS09825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C0W57_RS09830	COG0488	(ABC) transporter
C0W57_RS09840	COG0681	Belongs to the peptidase S26 family
C0W57_RS09845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0W57_RS09845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0W57_RS09845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0W57_RS09850	COG1105	Belongs to the carbohydrate kinase PfkB family
C0W57_RS09855	COG1349	DNA-binding transcription factor activity
C0W57_RS09860	COG0577	efflux transmembrane transporter activity
C0W57_RS09865	COG1136	(ABC) transporter
C0W57_RS09870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0W57_RS09880	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C0W57_RS09885	COG0314	molybdopterin synthase activity
C0W57_RS09890	COG1763	Mo-molybdopterin cofactor biosynthetic process
C0W57_RS09895	COG0303	'Molybdopterin
C0W57_RS09900	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C0W57_RS09920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0W57_RS09925	COG0668	transmembrane transport
C0W57_RS09945	COG0716	FMN binding
C0W57_RS09955	COG0716	FMN binding
C0W57_RS09960	COG0583	DNA-binding transcription factor activity
C0W57_RS09965	COG0517	IMP dehydrogenase activity
C0W57_RS09975	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C0W57_RS09980	COG4703	Protein of unknown function (DUF1797)
C0W57_RS09995	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS10000	COG1408	metallophosphoesterase
C0W57_RS10005	COG1376	ErfK ybiS ycfS ynhG family protein
C0W57_RS10010	COG2814	Major facilitator Superfamily
C0W57_RS10030	COG0436	Aminotransferase
C0W57_RS10035	COG4191	Histidine kinase
C0W57_RS10040	COG0768	penicillin binding
C0W57_RS10045	COG2340	Cysteine-rich secretory protein family
C0W57_RS10050	COG2084	Dehydrogenase
C0W57_RS10055	COG0840	transmembrane signaling receptor activity
C0W57_RS10060	COG1533	DNA photolyase activity
C0W57_RS10075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0W57_RS10080	COG2190	(PTS) system
C0W57_RS10080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0W57_RS10080	COG1263	PTS System
C0W57_RS10085	COG3711	transcriptional antiterminator
C0W57_RS10090	COG1609	Transcriptional regulator
C0W57_RS10095	COG0006	proline dipeptidase activity
C0W57_RS10100	COG2217	Heavy metal translocating P-type atpase
C0W57_RS10105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0W57_RS10110	COG2244	polysaccharide biosynthetic process
C0W57_RS10115	COG3773	Cell wall hydrolase
C0W57_RS10125	COG4873	Protein conserved in bacteria
C0W57_RS10145	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS10150	COG1733	regulation of RNA biosynthetic process
C0W57_RS10160	COG0602	queuosine metabolic process
C0W57_RS10165	COG0720	synthase
C0W57_RS10180	COG3949	Membrane
C0W57_RS10190	COG0542	response to heat
C0W57_RS10195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C0W57_RS10205	COG1846	Transcriptional regulator
C0W57_RS10210	COG3852	Histidine kinase
C0W57_RS10240	COG0436	Aminotransferase
C0W57_RS10245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0W57_RS10260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C0W57_RS10265	COG5002	protein histidine kinase activity
C0W57_RS10270	COG3594	Acyltransferase
C0W57_RS10285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C0W57_RS10310	COG1191	sigma factor activity
C0W57_RS10315	COG0861	Integral membrane protein TerC family
C0W57_RS10320	COG0586	Pfam SNARE associated Golgi protein
C0W57_RS10325	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C0W57_RS10330	COG1793	dna ligase
C0W57_RS10330	COG3285	dna ligase
C0W57_RS10335	COG0726	polysaccharide deacetylase
C0W57_RS10340	COG1846	Transcriptional regulator
C0W57_RS10355	COG0789	Transcriptional regulator
C0W57_RS10360	COG2239	Acts as a magnesium transporter
C0W57_RS10375	COG1388	LysM domain
C0W57_RS10375	COG3858	chitin binding
C0W57_RS10380	COG4721	ABC-type cobalt transport system, permease component
C0W57_RS10385	COG1122	ATPase activity
C0W57_RS10390	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C0W57_RS10395	COG1366	Belongs to the anti-sigma-factor antagonist family
C0W57_RS10400	COG1404	Belongs to the peptidase S8 family
C0W57_RS10410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0W57_RS10415	COG2814	Major facilitator Superfamily
C0W57_RS10425	COG0457	Tetratricopeptide repeat
C0W57_RS10425	COG0463	Glycosyl transferase, family 2
C0W57_RS10445	COG1764	response to oxidative stress
C0W57_RS10450	COG1846	Transcriptional regulator
C0W57_RS10455	COG1764	response to oxidative stress
C0W57_RS10465	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C0W57_RS10470	COG0788	formyltetrahydrofolate deformylase activity
C0W57_RS10475	COG2076	Multidrug Resistance protein
C0W57_RS10480	COG2076	Multidrug Resistance protein
C0W57_RS10485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0W57_RS10490	COG1607	acyl-coa hydrolase
C0W57_RS10495	COG1834	amidinotransferase
C0W57_RS10500	COG2706	6-phosphogluconolactonase activity
C0W57_RS10505	COG4608	Belongs to the ABC transporter superfamily
C0W57_RS10510	COG0791	NLP P60 protein
C0W57_RS10515	COG4948	Mandelate Racemase Muconate Lactonizing
C0W57_RS10520	COG1619	proteins homologs of microcin C7 resistance protein MccF
C0W57_RS10525	COG4166	transmembrane transport
C0W57_RS10530	COG0444	Belongs to the ABC transporter superfamily
C0W57_RS10535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0W57_RS10540	COG0601	transmembrane transport
C0W57_RS10545	COG2362	D-Aminopeptidase
C0W57_RS10550	COG0477	Major facilitator Superfamily
C0W57_RS10555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0W57_RS10560	COG0463	Glycosyl transferase, family 2
C0W57_RS10565	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C0W57_RS10570	COG0346	lactoylglutathione lyase activity
C0W57_RS10575	COG0531	amino acid
C0W57_RS10580	COG1392	Phosphate transport regulator
C0W57_RS10585	COG0306	phosphate transporter
C0W57_RS10600	COG3409	Peptidoglycan-binding domain 1 protein
C0W57_RS10600	COG5632	N-Acetylmuramoyl-L-alanine amidase
C0W57_RS10640	COG3778	Protein conserved in bacteria
C0W57_RS10645	COG3299	homolog of phage Mu protein gp47
C0W57_RS10650	COG3628	GPW Gp25 family protein
C0W57_RS10660	COG4193	domain, Protein
C0W57_RS10665	COG1652	LysM domain
C0W57_RS10670	COG3953	SLT domain
C0W57_RS10670	COG3953	SLT domain
C0W57_RS10670	COG5412	phage tail tape measure protein
C0W57_RS10670	COG5412	phage tail tape measure protein
C0W57_RS10670	COG5412	phage tail tape measure protein
C0W57_RS10670	COG3953	SLT domain
C0W57_RS10720	COG4653	Phage capsid family
C0W57_RS10725	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C0W57_RS10730	COG5518	Phage portal protein
C0W57_RS10735	COG1783	phage Terminase large subunit
C0W57_RS10740	COG3728	DNA packaging
C0W57_RS10740	COG5484	DNA packaging
C0W57_RS10745	COG1595	DNA-templated transcription, initiation
C0W57_RS10760	COG1484	DNA-dependent DNA replication
C0W57_RS10765	COG1522	sequence-specific DNA binding
C0W57_RS10775	COG1396	sequence-specific DNA binding
C0W57_RS10780	COG2856	Zn peptidase
C0W57_RS10785	COG3546	catalase activity
C0W57_RS10790	COG4195	phage-related replication protein
C0W57_RS10800	COG1388	LysM domain
C0W57_RS10800	COG3409	Peptidoglycan-binding domain 1 protein
C0W57_RS10800	COG5632	N-Acetylmuramoyl-L-alanine amidase
C0W57_RS10805	COG0457	Tetratricopeptide repeat
C0W57_RS10810	COG2318	DinB family
C0W57_RS10815	COG0730	response to heat
C0W57_RS10820	COG2721	sulfolactate sulfo-lyase activity
C0W57_RS10825	COG0246	Mannitol dehydrogenase
C0W57_RS10830	COG1609	Transcriptional regulator
C0W57_RS10835	COG2211	Major facilitator Superfamily
C0W57_RS10845	COG1252	NADH dehydrogenase
C0W57_RS10855	COG4297	protein containing double-stranded beta helix domain
C0W57_RS10860	COG0697	spore germination
C0W57_RS10865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C0W57_RS10870	COG0390	transport system, permease component
C0W57_RS10875	COG1587	Uroporphyrinogen-III synthase
C0W57_RS10885	COG1819	glycosyl
C0W57_RS10890	COG2124	cytochrome p450
C0W57_RS10895	COG2427	Protein of unknown function (DUF1641)
C0W57_RS10900	COG3383	formate dehydrogenase (NAD+) activity
C0W57_RS10910	COG2205	protein histidine kinase activity
C0W57_RS10925	COG1285	pathogenesis
C0W57_RS10955	COG1447	Phosphotransferase system cellobiose-specific component IIA
C0W57_RS10960	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C0W57_RS10960	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C0W57_RS10965	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C0W57_RS10970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C0W57_RS10975	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C0W57_RS10985	COG1846	Transcriptional regulator
C0W57_RS10990	COG0477	Major facilitator Superfamily
C0W57_RS10995	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C0W57_RS11000	COG2367	Beta-lactamase
C0W57_RS11065	COG0135	phosphoribosylanthranilate isomerase activity
C0W57_RS11085	COG5444	nuclease activity
C0W57_RS11115	COG0626	cystathionine gamma-synthase activity
C0W57_RS11120	COG0626	cystathionine gamma-synthase activity
C0W57_RS11125	COG2382	esterase
C0W57_RS11135	COG2153	protein acetylation
C0W57_RS11145	COG1131	(ABC) transporter
C0W57_RS11165	COG0210	DNA helicase
C0W57_RS11220	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C0W57_RS11225	COG0351	phosphomethylpyrimidine kinase
C0W57_RS11230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C0W57_RS11240	COG2104	thiamine diphosphate biosynthetic process
C0W57_RS11245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0W57_RS11250	COG0352	thiamine-phosphate diphosphorylase activity
C0W57_RS11255	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C0W57_RS11260	COG0569	domain protein
C0W57_RS11260	COG0475	glutathione-regulated potassium exporter activity
C0W57_RS11275	COG0564	pseudouridine synthase activity
C0W57_RS11280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C0W57_RS11285	COG2357	RelA SpoT domain protein
C0W57_RS11295	COG4116	CYTH
C0W57_RS11300	COG0741	lytic transglycosylase activity
C0W57_RS11305	COG2346	COG2346, Truncated hemoglobins
C0W57_RS11310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C0W57_RS11315	COG1164	Oligoendopeptidase f
C0W57_RS11320	COG4469	Competence protein
C0W57_RS11325	COG4862	establishment of competence for transformation
C0W57_RS11330	COG0861	Integral membrane protein TerC family
C0W57_RS11335	COG1393	Belongs to the ArsC family
C0W57_RS11340	COG0456	acetyltransferase
C0W57_RS11350	COG4608	Belongs to the ABC transporter superfamily
C0W57_RS11355	COG0444	Belongs to the ABC transporter superfamily
C0W57_RS11360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0W57_RS11365	COG0601	transmembrane transport
C0W57_RS11370	COG4166	transmembrane transport
C0W57_RS11375	COG0180	Tryptophanyl-tRNA synthetase
C0W57_RS11385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0W57_RS11390	COG0601	transmembrane transport
C0W57_RS11400	COG4608	Belongs to the ABC transporter superfamily
C0W57_RS11405	COG0444	Belongs to the ABC transporter superfamily
C0W57_RS11410	COG5504	Zn-dependent protease
C0W57_RS11415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C0W57_RS11420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0W57_RS11435	COG1744	ABC transporter substrate-binding protein PnrA-like
C0W57_RS11445	COG2267	carboxylic ester hydrolase activity
C0W57_RS11465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C0W57_RS11470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C0W57_RS11475	COG0505	Belongs to the CarA family
C0W57_RS11480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0W57_RS11490	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C0W57_RS11500	COG2271	Major facilitator Superfamily
C0W57_RS11505	COG0277	FAD linked oxidase domain protein
C0W57_RS11515	COG2151	metal-sulfur cluster biosynthetic enzyme
C0W57_RS11520	COG1073	alpha beta
C0W57_RS11525	COG0561	phosphatase activity
C0W57_RS11540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0W57_RS11545	COG1307	EDD domain protein, DegV family
C0W57_RS11555	COG2124	cytochrome p450
C0W57_RS11560	COG0840	transmembrane signaling receptor activity
C0W57_RS11565	COG1744	ABC transporter substrate-binding protein PnrA-like
C0W57_RS11570	COG2996	Protein conserved in bacteria
C0W57_RS11580	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C0W57_RS11580	COG0646	methionine synthase
C0W57_RS11585	COG2153	protein acetylation
C0W57_RS11590	COG1357	PFAM Pentapeptide repeats (8 copies)
C0W57_RS11600	COG2318	DinB family
C0W57_RS11605	COG0673	inositol 2-dehydrogenase activity
C0W57_RS11610	COG1609	Transcriptional regulator
C0W57_RS11615	COG1917	Cupin 2, conserved barrel domain protein
C0W57_RS11615	COG2207	Transcriptional regulator
C0W57_RS11620	COG0534	Mate efflux family protein
C0W57_RS11625	COG1562	ergosterol biosynthetic process
C0W57_RS11630	COG0367	asparagine synthase
C0W57_RS11645	COG0179	Fumarylacetoacetate (FAA) hydrolase
C0W57_RS11685	COG1403	HNH endonuclease
C0W57_RS11690	COG0419	ATPase involved in DNA repair
C0W57_RS11695	COG0420	3'-5' exonuclease activity
C0W57_RS11710	COG2323	membrane
C0W57_RS11715	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C0W57_RS11725	COG2814	Major facilitator Superfamily
C0W57_RS11730	COG3180	Ammonia monooxygenase
C0W57_RS11735	COG1846	Transcriptional regulator
C0W57_RS11740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0W57_RS11745	COG0681	Belongs to the peptidase S26 family
C0W57_RS11750	COG0398	Pfam SNARE associated Golgi protein
C0W57_RS11765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C0W57_RS11790	COG5646	InterPro IPR014922
C0W57_RS11800	COG4903	ComK protein
C0W57_RS11810	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS11815	COG0723	plastoquinol--plastocyanin reductase activity
C0W57_RS11815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0W57_RS11820	COG0840	transmembrane signaling receptor activity
C0W57_RS11825	COG1268	BioY protein
C0W57_RS11830	COG0318	PFAM AMP-dependent synthetase and ligase
C0W57_RS11835	COG0183	Belongs to the thiolase family
C0W57_RS11840	COG0406	alpha-ribazole phosphatase activity
C0W57_RS11845	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C0W57_RS11855	COG1404	Belongs to the peptidase S8 family
C0W57_RS11860	COG0501	Belongs to the peptidase M48B family
C0W57_RS11870	COG0318	PFAM AMP-dependent synthetase and ligase
C0W57_RS11875	COG0702	epimerase
C0W57_RS11880	COG0095	Lipoate-protein ligase
C0W57_RS11885	COG1234	tRNA 3'-trailer cleavage
C0W57_RS11895	COG1301	dicarboxylic acid transport
C0W57_RS11900	COG1363	Peptidase, m42
C0W57_RS11910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0W57_RS11915	COG1511	domain protein
C0W57_RS11920	COG1309	transcriptional regulator
C0W57_RS11925	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C0W57_RS11930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C0W57_RS11940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0W57_RS11945	COG2329	Antibiotic biosynthesis monooxygenase
C0W57_RS11950	COG3069	C4-dicarboxylate transmembrane transporter activity
C0W57_RS11955	COG1473	amidohydrolase
C0W57_RS11965	COG4473	ABC transporter
C0W57_RS11970	COG1131	(ABC) transporter
C0W57_RS11975	COG0537	adenosine 5'-monophosphoramidase activity
C0W57_RS11980	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C0W57_RS11995	COG4980	gas vesicle protein
C0W57_RS12035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0W57_RS12050	COG4717	serine-type aminopeptidase activity
C0W57_RS12055	COG0420	3'-5' exonuclease activity
C0W57_RS12060	COG1668	transmembrane transport
C0W57_RS12065	COG4152	abc transporter atp-binding protein
C0W57_RS12075	COG1024	Enoyl-CoA hydratase
C0W57_RS12085	COG0490	domain, Protein
C0W57_RS12090	COG0475	glutathione-regulated potassium exporter activity
C0W57_RS12100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C0W57_RS12105	COG0561	phosphatase activity
C0W57_RS12110	COG4335	DNA alkylation repair
C0W57_RS12125	COG0189	ligase activity
C0W57_RS12130	COG0189	ligase activity
C0W57_RS12150	COG0702	epimerase
C0W57_RS12155	COG1132	(ABC) transporter
C0W57_RS12165	COG0589	response to stress
C0W57_RS12175	COG3226	Transcriptional regulator
C0W57_RS12180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C0W57_RS12185	COG0726	polysaccharide deacetylase
C0W57_RS12190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C0W57_RS12195	COG0668	transmembrane transport
C0W57_RS12205	COG0584	glycerophosphoryl diester phosphodiesterase
C0W57_RS12210	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C0W57_RS12215	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C0W57_RS12220	COG1253	flavin adenine dinucleotide binding
C0W57_RS12225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C0W57_RS12230	COG0436	Aminotransferase
C0W57_RS12235	COG0789	Transcriptional regulator
C0W57_RS12240	COG1253	flavin adenine dinucleotide binding
C0W57_RS12245	COG0204	Acyl-transferase
C0W57_RS12250	COG1595	DNA-templated transcription, initiation
C0W57_RS12265	COG0733	neurotransmitter:sodium symporter activity
C0W57_RS12270	COG0531	amino acid
C0W57_RS12275	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS12280	COG0372	Belongs to the citrate synthase family
C0W57_RS12285	COG0583	DNA-binding transcription factor activity
C0W57_RS12290	COG0791	NLP P60 protein
C0W57_RS12290	COG1388	LysM domain
C0W57_RS12295	COG1785	Belongs to the alkaline phosphatase family
C0W57_RS12300	COG2719	SpoVR family
C0W57_RS12305	COG0668	transmembrane transport
C0W57_RS12310	COG1959	2 iron, 2 sulfur cluster binding
C0W57_RS12315	COG1388	LysM domain
C0W57_RS12315	COG0791	NLP P60 protein
C0W57_RS12330	COG0431	NADPH-dependent FMN reductase
C0W57_RS12335	COG2197	response regulator
C0W57_RS12340	COG2203	Gaf domain
C0W57_RS12340	COG4585	Histidine kinase
C0W57_RS12345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0W57_RS12350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C0W57_RS12360	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C0W57_RS12365	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C0W57_RS12370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C0W57_RS12375	COG3153	acetyltransferase
C0W57_RS12375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0W57_RS12380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0W57_RS12385	COG0517	IMP dehydrogenase activity
C0W57_RS12395	COG0564	pseudouridine synthase activity
C0W57_RS12400	COG3764	Sortase (surface protein transpeptidase)
C0W57_RS12405	COG4085	toxin activity
C0W57_RS12405	COG1525	nuclease
C0W57_RS12405	COG0737	Belongs to the 5'-nucleotidase family
C0W57_RS12410	COG5577	PFAM Coat F domain
C0W57_RS12430	COG1823	symporter activity
C0W57_RS12435	COG3706	GGDEF domain
C0W57_RS12440	COG1464	Belongs to the NlpA lipoprotein family
C0W57_RS12450	COG1278	Cold shock
C0W57_RS12455	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C0W57_RS12460	COG1131	(ABC) transporter
C0W57_RS12465	COG1131	(ABC) transporter
C0W57_RS12470	COG1725	Transcriptional regulator
C0W57_RS12485	COG0655	NAD(P)H dehydrogenase (quinone) activity
C0W57_RS12490	COG2814	Major facilitator Superfamily
C0W57_RS12495	COG1566	PFAM secretion protein HlyD family protein
C0W57_RS12500	COG1846	Transcriptional regulator
C0W57_RS12515	COG2766	serine protein kinase
C0W57_RS12525	COG1664	Polymer-forming cytoskeletal
C0W57_RS12530	COG1664	Polymer-forming cytoskeletal
C0W57_RS12540	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C0W57_RS12550	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C0W57_RS12555	COG3382	B3 4 domain protein
C0W57_RS12565	COG1476	TRANSCRIPTIONal
C0W57_RS12585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C0W57_RS12590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C0W57_RS12595	COG1116	anion transmembrane transporter activity
C0W57_RS12610	COG0753	catalase activity
C0W57_RS12615	COG4608	Belongs to the ABC transporter superfamily
C0W57_RS12620	COG0444	Belongs to the ABC transporter superfamily
C0W57_RS12625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0W57_RS12630	COG0601	transmembrane transport
C0W57_RS12635	COG0747	negative chemotaxis
C0W57_RS12645	COG0277	FAD linked oxidase domain protein
C0W57_RS12655	COG3340	Belongs to the peptidase S51 family
C0W57_RS12660	COG1757	Na H antiporter
C0W57_RS12695	COG3409	Peptidoglycan-binding domain 1 protein
C0W57_RS12695	COG5632	N-Acetylmuramoyl-L-alanine amidase
C0W57_RS12715	COG5434	Belongs to the glycosyl hydrolase 28 family
C0W57_RS12725	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0W57_RS12810	COG0582	viral genome integration into host DNA
C0W57_RS12855	COG1793	dna ligase
C0W57_RS12870	COG1595	DNA-templated transcription, initiation
C0W57_RS12900	COG1388	LysM domain
C0W57_RS12900	COG3584	3D domain protein
C0W57_RS12905	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
C0W57_RS12920	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0W57_RS12930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0W57_RS12940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0W57_RS12945	COG1780	Probably involved in ribonucleotide reductase function
C0W57_RS12970	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C0W57_RS12985	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0W57_RS12985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0W57_RS13060	COG1484	DNA-dependent DNA replication
C0W57_RS13115	COG4974	Belongs to the 'phage' integrase family
C0W57_RS13130	COG0628	permease
C0W57_RS13135	COG0673	inositol 2-dehydrogenase activity
C0W57_RS13140	COG0693	protein deglycase activity
C0W57_RS13145	COG0840	transmembrane signaling receptor activity
C0W57_RS13150	COG0840	transmembrane signaling receptor activity
C0W57_RS13155	COG0840	transmembrane signaling receptor activity
C0W57_RS13160	COG0840	transmembrane signaling receptor activity
C0W57_RS13175	COG2070	2-Nitropropane dioxygenase
C0W57_RS13180	COG0432	Pfam Uncharacterised protein family UPF0047
C0W57_RS13185	COG0366	Alpha amylase catalytic
C0W57_RS13190	COG1253	flavin adenine dinucleotide binding
C0W57_RS13195	COG2738	Putative neutral zinc metallopeptidase
C0W57_RS13210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C0W57_RS13240	COG1335	isochorismatase
C0W57_RS13245	COG1979	alcohol dehydrogenase
C0W57_RS13250	COG1979	alcohol dehydrogenase
C0W57_RS13255	COG2155	Conserved Protein
C0W57_RS13260	COG1098	S1 RNA binding domain
C0W57_RS13265	COG0436	Aminotransferase
C0W57_RS13270	COG1522	sequence-specific DNA binding
C0W57_RS13275	COG2267	carboxylic ester hydrolase activity
C0W57_RS13285	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C0W57_RS13290	COG2205	protein histidine kinase activity
C0W57_RS13300	COG5018	Exonuclease
C0W57_RS13305	COG2814	Major facilitator Superfamily
C0W57_RS13310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0W57_RS13315	COG3011	Protein conserved in bacteria
C0W57_RS13325	COG3290	protein histidine kinase activity
C0W57_RS13330	COG4565	transcriptional regulatory protein
C0W57_RS13335	COG1744	ABC transporter substrate-binding protein PnrA-like
C0W57_RS13340	COG3845	ABC transporter
C0W57_RS13345	COG4603	Belongs to the binding-protein-dependent transport system permease family
C0W57_RS13350	COG1079	Belongs to the binding-protein-dependent transport system permease family
C0W57_RS13360	COG2111	Na H antiporter
C0W57_RS13360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C0W57_RS13365	COG2111	Na H antiporter
C0W57_RS13370	COG1006	Multisubunit Na H antiporter MnhC subunit
C0W57_RS13375	COG0651	ATP synthesis coupled electron transport
C0W57_RS13380	COG1863	multisubunit Na H antiporter MnhE subunit
C0W57_RS13385	COG2212	antiporter activity
C0W57_RS13390	COG1320	monovalent cation:proton antiporter activity
C0W57_RS13395	COG2050	protein possibly involved in aromatic compounds catabolism
C0W57_RS13400	COG2197	response regulator
C0W57_RS13405	COG4585	Histidine kinase
C0W57_RS13435	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C0W57_RS13440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C0W57_RS13445	COG1335	isochorismatase
C0W57_RS13450	COG5506	Protein of unknown function (DUF1694)
C0W57_RS13465	COG0628	permease
C0W57_RS13475	COG1418	mRNA catabolic process
C0W57_RS13480	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS13490	COG1511	domain protein
C0W57_RS13495	COG1674	ftsk spoiiie
C0W57_RS13495	COG0433	COG0433 Predicted ATPase
C0W57_RS13500	COG4499	WXG100 protein secretion system (Wss), protein YukC
C0W57_RS13505	COG5417	Belongs to the EsaB family
C0W57_RS13510	COG4842	Belongs to the WXG100 family
C0W57_RS13515	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C0W57_RS13515	COG2508	Transcriptional regulator
C0W57_RS13520	COG0686	Belongs to the AlaDH PNT family
C0W57_RS13525	COG5634	Uncharacterized conserved protein (DUF2278)
C0W57_RS13530	COG3251	PFAM MbtH domain protein
C0W57_RS13535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS13540	COG1535	isochorismatase
C0W57_RS13540	COG3433	isochorismatase activity
C0W57_RS13545	COG1021	2,3-dihydroxybenzoate-AMP ligase
C0W57_RS13550	COG1169	isochorismate synthase
C0W57_RS13555	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS13560	COG2819	hydrolase of the alpha beta superfamily
C0W57_RS13565	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C0W57_RS13570	COG1268	BioY protein
C0W57_RS13575	COG2056	Na+-H+ antiporter family
C0W57_RS13585	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C0W57_RS13590	COG3584	3D domain protein
C0W57_RS13605	COG1252	NADH dehydrogenase
C0W57_RS13635	COG1131	(ABC) transporter
C0W57_RS13655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0W57_RS13660	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C0W57_RS13665	COG0316	Belongs to the HesB IscA family
C0W57_RS13675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C0W57_RS13685	COG1252	NADH dehydrogenase
C0W57_RS13690	COG4837	Protein of unknown function (DUF1462)
C0W57_RS13695	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C0W57_RS13700	COG4946	Tricorn protease homolog
C0W57_RS13700	COG0823	Involved in the tonB-independent uptake of proteins
C0W57_RS13700	COG1506	peptidase
C0W57_RS13710	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C0W57_RS13715	COG0460	homoserine dehydrogenase
C0W57_RS13720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C0W57_RS13725	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C0W57_RS13730	COG0647	UMP catabolic process
C0W57_RS13735	COG2445	Protein of unknown function DUF86
C0W57_RS13740	COG4470	Protein conserved in bacteria
C0W57_RS13755	COG0739	heme binding
C0W57_RS13765	COG0737	Belongs to the 5'-nucleotidase family
C0W57_RS13770	COG0730	response to heat
C0W57_RS13775	COG1801	Protein of unknown function DUF72
C0W57_RS13790	COG2508	Transcriptional regulator
C0W57_RS13795	COG0457	Tetratricopeptide repeat
C0W57_RS13810	COG2814	Major facilitator Superfamily
C0W57_RS13815	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C0W57_RS13820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0W57_RS13825	COG2356	endonuclease I
C0W57_RS13830	COG3842	ATPase activity
C0W57_RS13835	COG2188	Transcriptional regulator
C0W57_RS13840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0W57_RS13845	COG0395	ABC-type sugar transport system, permease component
C0W57_RS13850	COG1175	transmembrane transport
C0W57_RS13855	COG1653	transport
C0W57_RS13860	COG2222	sugar isomerase
C0W57_RS13865	COG0789	Transcriptional regulator
C0W57_RS13890	COG0322	excinuclease ABC activity
C0W57_RS13895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0W57_RS13915	COG3409	Peptidoglycan-binding domain 1 protein
C0W57_RS13920	COG0719	Fe-S assembly protein
C0W57_RS13925	COG0822	iron-sulfur transferase activity
C0W57_RS13930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C0W57_RS13935	COG0719	Fe-S assembly protein
C0W57_RS13940	COG0396	ATPase activity
C0W57_RS13950	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C0W57_RS13955	COG1464	Belongs to the NlpA lipoprotein family
C0W57_RS13960	COG2011	ABC-type metal ion transport system permease component
C0W57_RS13965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C0W57_RS13975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0W57_RS13980	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C0W57_RS13995	COG1393	Belongs to the ArsC family
C0W57_RS14000	COG1960	acyl-CoA dehydrogenase activity
C0W57_RS14005	COG0183	Belongs to the thiolase family
C0W57_RS14010	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0W57_RS14010	COG1024	Enoyl-CoA hydratase
C0W57_RS14030	COG5577	PFAM Coat F domain
C0W57_RS14035	COG1846	Transcriptional regulator
C0W57_RS14040	COG0477	Major facilitator Superfamily
C0W57_RS14045	COG0583	DNA-binding transcription factor activity
C0W57_RS14065	COG1120	ATPase activity
C0W57_RS14080	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS14085	COG0783	Belongs to the Dps family
C0W57_RS14090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0W57_RS14095	COG0745	RESPONSE REGULATOR receiver
C0W57_RS14100	COG2770	Histidine kinase
C0W57_RS14100	COG2205	protein histidine kinase activity
C0W57_RS14110	COG1309	transcriptional regulator
C0W57_RS14115	COG0114	fumarate hydratase activity
C0W57_RS14125	COG0697	spore germination
C0W57_RS14130	COG0814	amino acid
C0W57_RS14140	COG2197	response regulator
C0W57_RS14145	COG4585	Histidine kinase
C0W57_RS14150	COG4758	membrane
C0W57_RS14155	COG3595	metallopeptidase activity
C0W57_RS14160	COG1842	Phage shock protein A
C0W57_RS14165	COG4758	membrane
C0W57_RS14170	COG2814	Major facilitator Superfamily
C0W57_RS14175	COG2096	Adenosyltransferase
C0W57_RS14180	COG1120	ATPase activity
C0W57_RS14185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0W57_RS14190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0W57_RS14195	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS14200	COG3386	PFAM SMP-30 Gluconolaconase
C0W57_RS14205	COG2205	protein histidine kinase activity
C0W57_RS14210	COG0745	RESPONSE REGULATOR receiver
C0W57_RS14220	COG1191	sigma factor activity
C0W57_RS14230	COG2140	Oxalate decarboxylase
C0W57_RS14240	COG1120	ATPase activity
C0W57_RS14245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0W57_RS14250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0W57_RS14255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0W57_RS14260	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C0W57_RS14265	COG0531	amino acid
C0W57_RS14280	COG1988	membrane-bound metal-dependent
C0W57_RS14285	COG1368	sulfuric ester hydrolase activity
C0W57_RS14290	COG1910	domain protein
C0W57_RS14295	COG0725	ABC transporter, periplasmic molybdate-binding protein
C0W57_RS14300	COG4149	molybdate abc transporter
C0W57_RS14305	COG2197	response regulator
C0W57_RS14310	COG3850	Histidine kinase
C0W57_RS14315	COG1131	(ABC) transporter
C0W57_RS14325	COG0842	Transport permease protein
C0W57_RS14330	COG0656	L-ascorbic acid biosynthetic process
C0W57_RS14355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C0W57_RS14360	COG3973	AAA domain
C0W57_RS14365	COG2860	membrane
C0W57_RS14375	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C0W57_RS14380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C0W57_RS14385	COG2217	Heavy metal translocating P-type atpase
C0W57_RS14395	COG2608	mercury ion transmembrane transporter activity
C0W57_RS14400	COG1937	Protein conserved in bacteria
C0W57_RS14405	COG0673	inositol 2-dehydrogenase activity
C0W57_RS14415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0W57_RS14420	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C0W57_RS14425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0W57_RS14430	COG1126	abc transporter atp-binding protein
C0W57_RS14435	COG0765	amino acid transport
C0W57_RS14440	COG0765	amino acid transport
C0W57_RS14445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0W57_RS14450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0W57_RS14455	COG0454	-acetyltransferase
C0W57_RS14460	COG0583	DNA-binding transcription factor activity
C0W57_RS14465	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS14470	COG2732	(Barnase) inhibitor
C0W57_RS14480	COG2732	(Barnase) inhibitor
C0W57_RS14495	COG0557	exoribonuclease II activity
C0W57_RS14500	COG1647	Serine aminopeptidase, S33
C0W57_RS14505	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C0W57_RS14510	COG1476	TRANSCRIPTIONal
C0W57_RS14515	COG1396	sequence-specific DNA binding
C0W57_RS14520	COG1396	sequence-specific DNA binding
C0W57_RS14525	COG1733	regulation of RNA biosynthetic process
C0W57_RS14550	COG1131	(ABC) transporter
C0W57_RS14555	COG1174	glycine betaine transport
C0W57_RS14560	COG1732	Glycine betaine
C0W57_RS14565	COG1174	glycine betaine transport
C0W57_RS14570	COG1125	glycine betaine transport
C0W57_RS14570	COG0517	IMP dehydrogenase activity
C0W57_RS14575	COG1510	regulation of RNA biosynthetic process
C0W57_RS14580	COG1174	glycine betaine transport
C0W57_RS14585	COG1732	Glycine betaine
C0W57_RS14590	COG1174	glycine betaine transport
C0W57_RS14595	COG1125	glycine betaine transport
C0W57_RS14595	COG0517	IMP dehydrogenase activity
C0W57_RS14600	COG1510	regulation of RNA biosynthetic process
C0W57_RS14605	COG2095	MarC family integral membrane protein
C0W57_RS14615	COG3064	Membrane
C0W57_RS14620	COG4640	response to antibiotic
C0W57_RS14625	COG0456	acetyltransferase
C0W57_RS14645	COG0126	phosphoglycerate kinase activity
C0W57_RS14655	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C0W57_RS14660	COG2390	Transcriptional regulator
C0W57_RS14665	COG2814	Major facilitator Superfamily
C0W57_RS14670	COG1609	Transcriptional regulator
C0W57_RS14675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0W57_RS14680	COG0583	DNA-binding transcription factor activity
C0W57_RS14685	COG0697	spore germination
C0W57_RS14690	COG1113	amino acid transport
C0W57_RS14695	COG1737	Transcriptional regulator
C0W57_RS14700	COG1070	Carbohydrate kinase
C0W57_RS14735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0W57_RS14740	COG2186	Transcriptional regulator
C0W57_RS14745	COG1620	l-lactate permease
C0W57_RS14750	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C0W57_RS14760	COG5039	Polysaccharide pyruvyl transferase
C0W57_RS14765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C0W57_RS14770	COG0110	maltose O-acetyltransferase activity
C0W57_RS14775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C0W57_RS14780	COG2244	polysaccharide biosynthetic process
C0W57_RS14785	COG1216	Glycosyl transferase, family 2
C0W57_RS14790	COG5039	Polysaccharide pyruvyl transferase
C0W57_RS14795	COG1216	Glycosyl transferase, family 2
C0W57_RS14805	COG0438	transferase activity, transferring glycosyl groups
C0W57_RS14810	COG1215	transferase activity, transferring glycosyl groups
C0W57_RS14815	COG0438	transferase activity, transferring glycosyl groups
C0W57_RS14820	COG1086	Polysaccharide biosynthesis protein
C0W57_RS14825	COG0489	protein tyrosine kinase activity
C0W57_RS14830	COG3944	biosynthesis protein
C0W57_RS14835	COG1396	sequence-specific DNA binding
C0W57_RS14840	COG2272	Belongs to the type-B carboxylesterase lipase family
C0W57_RS14850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C0W57_RS14855	COG2364	Membrane
C0W57_RS14860	COG0456	acetyltransferase
C0W57_RS14865	COG3479	Phenolic acid decarboxylase
C0W57_RS14925	COG2223	nitrite transmembrane transporter activity
C0W57_RS14930	COG1609	Transcriptional regulator
C0W57_RS14940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0W57_RS14945	COG0366	Alpha amylase catalytic
C0W57_RS14950	COG1554	hydrolase, family 65, central catalytic
C0W57_RS14955	COG5521	maltodextrose utilization protein MalA
C0W57_RS14960	COG3833	ABC-type maltose transport systems, permease component
C0W57_RS14965	COG1175	transmembrane transport
C0W57_RS14970	COG2182	Extracellular solute-binding protein
C0W57_RS14975	COG0366	Alpha amylase catalytic
C0W57_RS14980	COG1609	Transcriptional regulator
C0W57_RS14985	COG1611	Belongs to the LOG family
C0W57_RS14990	COG1694	Mazg nucleotide pyrophosphohydrolase
C0W57_RS14995	COG0659	secondary active sulfate transmembrane transporter activity
C0W57_RS15000	COG0288	reversible hydration of carbon dioxide
C0W57_RS15010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0W57_RS15015	COG4290	ribonuclease
C0W57_RS15020	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C0W57_RS15025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0W57_RS15035	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C0W57_RS15045	COG1051	belongs to the nudix hydrolase family
C0W57_RS15050	COG0492	ferredoxin-NADP+ reductase activity
C0W57_RS15055	COG3883	PFAM NLP P60 protein
C0W57_RS15055	COG0791	NLP P60 protein
C0W57_RS15060	COG0457	Tetratricopeptide repeat
C0W57_RS15065	COG5002	protein histidine kinase activity
C0W57_RS15070	COG0745	RESPONSE REGULATOR receiver
C0W57_RS15080	COG1132	(ABC) transporter
C0W57_RS15085	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C0W57_RS15085	COG0140	phosphoribosyl-ATP diphosphatase activity
C0W57_RS15110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C0W57_RS15125	COG4990	cell redox homeostasis
C0W57_RS15130	COG0110	maltose O-acetyltransferase activity
C0W57_RS15150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C0W57_RS15160	COG2188	Transcriptional regulator
C0W57_RS15165	COG1309	transcriptional regulator
C0W57_RS15170	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C0W57_RS15175	COG1950	PFAM Membrane protein of
C0W57_RS15180	COG1983	PspC domain protein
C0W57_RS15185	COG3595	metallopeptidase activity
C0W57_RS15200	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C0W57_RS15210	COG4897	Protein conserved in bacteria
C0W57_RS15215	COG0574	Belongs to the PEP-utilizing enzyme family
C0W57_RS15215	COG3848	Pyruvate phosphate dikinase
C0W57_RS15220	COG1309	transcriptional regulator
C0W57_RS15225	COG2814	Major facilitator Superfamily
C0W57_RS15260	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS15275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0W57_RS15285	COG3409	Peptidoglycan-binding domain 1 protein
C0W57_RS15285	COG0793	Belongs to the peptidase S41A family
C0W57_RS15290	COG3420	alginic acid biosynthetic process
C0W57_RS15295	COG2177	Part of the ABC transporter FtsEX involved in
C0W57_RS15300	COG2884	Cell division ATP-binding protein ftsE
C0W57_RS15305	COG2010	Cytochrome c
C0W57_RS15310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0W57_RS15315	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C0W57_RS15325	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C0W57_RS15340	COG1516	flagellar protein fliS
C0W57_RS15345	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C0W57_RS15350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C0W57_RS15370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C0W57_RS15375	COG1256	bacterial-type flagellum assembly
C0W57_RS15375	COG4786	Flagellar basal body rod
C0W57_RS15380	COG3418	PFAM FlgN family protein
C0W57_RS15385	COG2747	anti-sigma28 factor FlgM
C0W57_RS15395	COG1040	competence protein
C0W57_RS15405	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C0W57_RS15410	COG1307	EDD domain protein, DegV family
C0W57_RS15415	COG2197	response regulator
C0W57_RS15420	COG4585	Histidine kinase
C0W57_RS15425	COG1739	Uncharacterized protein family UPF0029
C0W57_RS15430	COG1316	TRANSCRIPTIONal
C0W57_RS15435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C0W57_RS15440	COG0438	transferase activity, transferring glycosyl groups
C0W57_RS15445	COG1215	transferase activity, transferring glycosyl groups
C0W57_RS15450	COG3206	protein involved in exopolysaccharide biosynthesis
C0W57_RS15455	COG3307	-O-antigen
C0W57_RS15460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C0W57_RS15465	COG0297	glycogen (starch) synthase activity
C0W57_RS15465	COG0438	transferase activity, transferring glycosyl groups
C0W57_RS15470	COG2244	polysaccharide biosynthetic process
C0W57_RS15480	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0W57_RS15480	COG2247	cell wall binding repeat
C0W57_RS15485	COG2247	cell wall binding repeat
C0W57_RS15485	COG2385	sporulation resulting in formation of a cellular spore
C0W57_RS15495	COG1316	TRANSCRIPTIONal
C0W57_RS15500	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C0W57_RS15505	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C0W57_RS15510	COG1134	teichoic acid transport
C0W57_RS15515	COG1682	transport, permease protein
C0W57_RS15520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C0W57_RS15525	COG0438	transferase activity, transferring glycosyl groups
C0W57_RS15530	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C0W57_RS15535	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C0W57_RS15540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C0W57_RS15545	COG4193	domain, Protein
C0W57_RS15550	COG1482	cell wall glycoprotein biosynthetic process
C0W57_RS15555	COG0697	spore germination
C0W57_RS15560	COG0814	amino acid
C0W57_RS15570	COG1215	transferase activity, transferring glycosyl groups
C0W57_RS15575	COG2814	Major facilitator Superfamily
C0W57_RS15580	COG1316	TRANSCRIPTIONal
C0W57_RS15585	COG0561	phosphatase activity
C0W57_RS15590	COG2433	Pfam Transposase IS66
C0W57_RS15595	COG0791	NLP P60 protein
C0W57_RS15605	COG2843	Capsule synthesis protein
C0W57_RS15615	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C0W57_RS15625	COG0697	spore germination
C0W57_RS15630	COG0814	amino acid
C0W57_RS15640	COG1609	Transcriptional regulator
C0W57_RS15645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0W57_RS15655	COG1129	ABC transporter
C0W57_RS15660	COG1172	Belongs to the binding-protein-dependent transport system permease family
C0W57_RS15665	COG1879	ABC-type sugar transport system periplasmic component
C0W57_RS15670	COG3103	Sh3 type 3 domain protein
C0W57_RS15675	COG2249	NAD(P)H dehydrogenase (quinone) activity
C0W57_RS15680	COG3527	Alpha-acetolactate decarboxylase
C0W57_RS15685	COG0028	Belongs to the TPP enzyme family
C0W57_RS15690	COG0583	DNA-binding transcription factor activity
C0W57_RS15695	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C0W57_RS15710	COG5337	Spore coat protein CotH
C0W57_RS15720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C0W57_RS15730	COG0405	Gamma-glutamyltransferase
C0W57_RS15735	COG1522	sequence-specific DNA binding
C0W57_RS15740	COG2059	Chromate
C0W57_RS15745	COG2059	Chromate
C0W57_RS15755	COG0655	NAD(P)H dehydrogenase (quinone) activity
C0W57_RS15760	COG0583	DNA-binding transcription factor activity
C0W57_RS15775	COG5444	nuclease activity
C0W57_RS15790	COG3878	Protein conserved in bacteria
C0W57_RS15795	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C0W57_RS15800	COG4464	protein tyrosine phosphatase activity
C0W57_RS15805	COG0489	protein tyrosine kinase activity
C0W57_RS15810	COG3944	biosynthesis protein
C0W57_RS15825	COG4715	Zinc finger, swim domain protein
C0W57_RS15830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C0W57_RS15835	COG0561	phosphatase activity
C0W57_RS15840	COG1349	DNA-binding transcription factor activity
C0W57_RS15845	COG0629	single-stranded DNA binding
C0W57_RS15870	COG0457	Tetratricopeptide repeat
C0W57_RS15875	COG4786	Flagellar basal body rod
C0W57_RS15880	COG4786	Flagellar basal body rod
C0W57_RS15885	COG1077	Cell shape determining protein MreB Mrl
C0W57_RS15890	COG1609	Transcriptional regulator
C0W57_RS15895	COG1846	Transcriptional regulator
C0W57_RS15900	COG2814	Major facilitator Superfamily
C0W57_RS15905	COG1953	Uracil, thiamine, allantoin
C0W57_RS15910	COG0477	Major facilitator Superfamily
C0W57_RS15915	COG1335	isochorismatase
C0W57_RS15920	COG0004	ammonium transporteR
C0W57_RS15925	COG0347	Belongs to the P(II) protein family
C0W57_RS15930	COG0772	Belongs to the SEDS family
C0W57_RS15935	COG0671	phosphoesterase, PA-phosphatase related
C0W57_RS15945	COG0739	heme binding
C0W57_RS15950	COG1247	-acetyltransferase
C0W57_RS15965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0W57_RS15975	COG0726	polysaccharide deacetylase
C0W57_RS15985	COG1959	2 iron, 2 sulfur cluster binding
C0W57_RS16000	COG0831	urea catabolic process
C0W57_RS16010	COG1994	Peptidase M50
C0W57_RS16015	COG0457	Tetratricopeptide repeat
C0W57_RS16025	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C0W57_RS16030	COG2304	oxidoreductase activity
C0W57_RS16035	COG2304	oxidoreductase activity
C0W57_RS16045	COG2385	sporulation resulting in formation of a cellular spore
C0W57_RS16050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C0W57_RS16060	COG4836	Membrane
C0W57_RS16130	COG0698	ribose 5-phosphate isomerase
C0W57_RS16135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C0W57_RS16145	COG0009	L-threonylcarbamoyladenylate synthase
C0W57_RS16150	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C0W57_RS16170	COG2890	protein-(glutamine-N5) methyltransferase activity
C0W57_RS16175	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C0W57_RS16180	COG0346	lactoylglutathione lyase activity
C0W57_RS16185	COG0789	Transcriptional regulator
C0W57_RS16190	COG0679	Auxin Efflux Carrier
C0W57_RS16195	COG0281	malic enzyme
C0W57_RS16210	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C0W57_RS16215	COG1494	fructose-1,6-bisphosphatase
C0W57_RS16220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C0W57_RS16230	COG0191	fructose-bisphosphate aldolase activity
C0W57_RS16235	COG2204	response regulator
C0W57_RS16240	COG4821	SIS domain
C0W57_RS16255	COG2181	nitrate reductase activity
C0W57_RS16255	COG0247	lactate metabolic process
C0W57_RS16260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0W57_RS16275	COG1132	(ABC) transporter
C0W57_RS16280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0W57_RS16290	COG2181	nitrate reductase activity
C0W57_RS16295	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C0W57_RS16300	COG1140	nitrate reductase beta subunit
C0W57_RS16305	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C0W57_RS16310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0W57_RS16320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0W57_RS16325	COG2223	nitrite transmembrane transporter activity
C0W57_RS16335	COG4506	Protein conserved in bacteria
C0W57_RS16340	COG0457	Tetratricopeptide repeat
C0W57_RS16385	COG0010	Belongs to the arginase family
C0W57_RS16390	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C0W57_RS16395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0W57_RS16410	COG1994	Peptidase M50
C0W57_RS16415	COG1942	4-Oxalocrotonate Tautomerase
C0W57_RS16420	COG1846	Transcriptional regulator
C0W57_RS16430	COG0531	amino acid
C0W57_RS16435	COG3465	dGTPase activity
C0W57_RS16440	COG1078	dGTPase activity
C0W57_RS16455	COG1695	Transcriptional regulator
C0W57_RS16465	COG1131	(ABC) transporter
C0W57_RS16500	COG0583	DNA-binding transcription factor activity
C0W57_RS16505	COG2855	membrane
C0W57_RS16510	COG0280	phosphate acetyltransferase
C0W57_RS16520	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS16525	COG0436	Aminotransferase
C0W57_RS16560	COG2814	Major facilitator Superfamily
C0W57_RS16565	COG0833	amino acid
C0W57_RS16570	COG4187	Peptidase family M20/M25/M40
C0W57_RS16575	COG1012	belongs to the aldehyde dehydrogenase family
C0W57_RS16580	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C0W57_RS16585	COG2205	protein histidine kinase activity
C0W57_RS16590	COG0745	RESPONSE REGULATOR receiver
C0W57_RS16605	COG1131	(ABC) transporter
C0W57_RS16610	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C0W57_RS16615	COG1091	dTDP-4-dehydrorhamnose reductase activity
C0W57_RS16620	COG1088	dTDP-glucose 4,6-dehydratase activity
C0W57_RS16625	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C0W57_RS16630	COG3980	spore coat polysaccharide biosynthesis protein
C0W57_RS16635	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C0W57_RS16640	COG2089	acid synthase
C0W57_RS16645	COG0456	acetyltransferase
C0W57_RS16650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C0W57_RS16655	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C0W57_RS16660	COG0463	Glycosyl transferase, family 2
C0W57_RS16670	COG2363	Small membrane protein
C0W57_RS16675	COG2233	PERMEase
C0W57_RS16690	COG1216	Glycosyl transferase, family 2
C0W57_RS16705	COG1695	Transcriptional regulator
C0W57_RS16710	COG0351	phosphomethylpyrimidine kinase
C0W57_RS16720	COG1621	beta-fructofuranosidase activity
C0W57_RS16725	COG1263	PTS System
C0W57_RS16725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0W57_RS16730	COG3711	transcriptional antiterminator
C0W57_RS16740	COG1404	Belongs to the peptidase S8 family
C0W57_RS16745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0W57_RS16750	COG0778	Nitroreductase
C0W57_RS16755	COG0772	Belongs to the SEDS family
C0W57_RS16760	COG0454	-acetyltransferase
C0W57_RS16780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C0W57_RS16785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C0W57_RS16790	COG2261	transglycosylase associated protein
C0W57_RS16795	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C0W57_RS16805	COG2246	polysaccharide biosynthetic process
C0W57_RS16810	COG1309	transcriptional regulator
C0W57_RS16830	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C0W57_RS16835	COG2837	iron assimilation
C0W57_RS16840	COG2822	iron ion transport
C0W57_RS16855	COG0583	DNA-binding transcription factor activity
C0W57_RS16865	COG1346	cytolysis
C0W57_RS16870	COG4895	conserved protein (DUF2196)
C0W57_RS16875	COG0789	Transcriptional regulator
C0W57_RS16880	COG5504	Zn-dependent protease
C0W57_RS16885	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C0W57_RS16890	COG0346	lactoylglutathione lyase activity
C0W57_RS16895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C0W57_RS16900	COG1404	Belongs to the peptidase S8 family
C0W57_RS16905	COG1442	glycosyl transferase family 8
C0W57_RS16910	COG1846	Transcriptional regulator
C0W57_RS16915	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C0W57_RS16920	COG2357	RelA SpoT domain protein
C0W57_RS16925	COG1575	Belongs to the MenA family. Type 1 subfamily
C0W57_RS16945	COG1696	Membrane protein involved in D-alanine export
C0W57_RS16955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C0W57_RS16960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C0W57_RS16965	COG1486	melibiose metabolic process
C0W57_RS16970	COG1447	Phosphotransferase system cellobiose-specific component IIA
C0W57_RS16975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C0W57_RS16980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C0W57_RS16985	COG3711	transcriptional antiterminator
C0W57_RS16985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0W57_RS17000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0W57_RS17005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0W57_RS17015	COG0640	Transcriptional regulator
C0W57_RS17020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C0W57_RS17025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C0W57_RS17030	COG1447	Phosphotransferase system cellobiose-specific component IIA
C0W57_RS17035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C0W57_RS17040	COG2723	6-phospho-beta-galactosidase activity
C0W57_RS17045	COG1940	carbohydrate kinase activity
C0W57_RS17050	COG1482	cell wall glycoprotein biosynthetic process
C0W57_RS17060	COG0753	catalase activity
C0W57_RS17065	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C0W57_RS17070	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C0W57_RS17075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C0W57_RS17080	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C0W57_RS17085	COG4988	ABC transporter
C0W57_RS17090	COG1294	oxidase, subunit
C0W57_RS17095	COG1271	oxidase subunit
C0W57_RS17100	COG3493	citrate carrier protein
C0W57_RS17105	COG0726	polysaccharide deacetylase
C0W57_RS17110	COG3842	ATPase activity
C0W57_RS17115	COG2508	Transcriptional regulator
C0W57_RS17120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0W57_RS17130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C0W57_RS17140	COG4894	glucomannan catabolic process
C0W57_RS17145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C0W57_RS17150	COG0500	methyltransferase
C0W57_RS17155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C0W57_RS17175	COG0693	protein deglycase activity
C0W57_RS17175	COG0753	catalase activity
C0W57_RS17180	COG2851	Citrate transporter
C0W57_RS17185	COG2273	Hydrolase Family 16
C0W57_RS17190	COG3711	transcriptional antiterminator
C0W57_RS17195	COG2270	Major facilitator Superfamily
C0W57_RS17200	COG0513	Belongs to the DEAD box helicase family
C0W57_RS17290	COG3209	COG3209 Rhs family protein
C0W57_RS17300	COG0697	spore germination
C0W57_RS17305	COG0589	response to stress
C0W57_RS17315	COG0494	nUDIX hydrolase
C0W57_RS17320	COG3507	Belongs to the glycosyl hydrolase 43 family
C0W57_RS17345	COG0010	Belongs to the arginase family
C0W57_RS17350	COG0833	amino acid
C0W57_RS17355	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C0W57_RS17360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C0W57_RS17370	COG2390	Transcriptional regulator
C0W57_RS17375	COG0561	phosphatase activity
C0W57_RS17405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0W57_RS17410	COG5294	Protein conserved in bacteria
C0W57_RS17415	COG0577	efflux transmembrane transporter activity
C0W57_RS17420	COG1136	(ABC) transporter
C0W57_RS17425	COG2205	protein histidine kinase activity
C0W57_RS17430	COG0745	RESPONSE REGULATOR receiver
C0W57_RS17435	COG2205	protein histidine kinase activity
C0W57_RS17440	COG0745	RESPONSE REGULATOR receiver
C0W57_RS17470	COG1082	Xylose isomerase domain protein TIM barrel
C0W57_RS17480	COG2814	Major facilitator Superfamily
C0W57_RS17510	COG1349	DNA-binding transcription factor activity
C0W57_RS17515	COG0667	Aldo Keto reductase
C0W57_RS17520	COG2814	Major facilitator Superfamily
C0W57_RS17535	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS17540	COG2197	response regulator
C0W57_RS17545	COG4585	Histidine kinase
C0W57_RS17550	COG3239	Fatty acid desaturase
C0W57_RS17560	COG1309	transcriptional regulator
C0W57_RS17565	COG1012	belongs to the aldehyde dehydrogenase family
C0W57_RS17570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0W57_RS17580	COG0640	Transcriptional regulator
C0W57_RS17585	COG2814	Major facilitator Superfamily
C0W57_RS17590	COG1714	RDD family
C0W57_RS17600	COG0501	Belongs to the peptidase M48B family
C0W57_RS17605	COG1715	Restriction endonuclease
C0W57_RS17610	COG0450	alkyl hydroperoxide reductase
C0W57_RS17615	COG3634	alkyl hydroperoxide reductase activity
C0W57_RS17630	COG1113	amino acid transport
C0W57_RS17640	COG2080	2 iron, 2 sulfur cluster binding
C0W57_RS17655	COG2068	MobA-Related Protein
C0W57_RS17660	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C0W57_RS17705	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C0W57_RS17710	COG0667	Aldo Keto reductase
C0W57_RS17715	COG0456	acetyltransferase
C0W57_RS17720	COG0457	Tetratricopeptide repeat
C0W57_RS17725	COG0010	Belongs to the arginase family
C0W57_RS17730	COG0833	amino acid
C0W57_RS17735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0W57_RS17740	COG3829	transcription factor binding
C0W57_RS17750	COG0488	(ABC) transporter
C0W57_RS17765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C0W57_RS17770	COG5002	protein histidine kinase activity
C0W57_RS17775	COG0745	RESPONSE REGULATOR receiver
C0W57_RS17785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0W57_RS17790	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C0W57_RS17795	COG4853	Protein conserved in bacteria
C0W57_RS17800	COG4863	YycH protein
C0W57_RS17805	COG5002	protein histidine kinase activity
C0W57_RS17810	COG0745	RESPONSE REGULATOR receiver
C0W57_RS17845	COG0346	lactoylglutathione lyase activity
C0W57_RS17850	COG0305	Participates in initiation and elongation during chromosome replication
C0W57_RS17865	COG3093	addiction module antidote protein HigA
C0W57_RS17870	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C0W57_RS17885	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C0W57_RS17900	COG2112	serine threonine protein kinase
C0W57_RS17910	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C0W57_RS17915	COG4241	membrane
C0W57_RS17925	COG5577	PFAM Coat F domain
C0W57_RS17930	COG1733	regulation of RNA biosynthetic process
C0W57_RS17940	COG0697	spore germination
C0W57_RS17945	COG1621	beta-fructofuranosidase activity
C0W57_RS17950	COG1621	beta-fructofuranosidase activity
C0W57_RS17955	COG1802	Transcriptional regulator
C0W57_RS17960	COG2318	DinB family
C0W57_RS17965	COG2211	Major facilitator Superfamily
C0W57_RS17980	COG0778	Nitroreductase
C0W57_RS17985	COG1846	Transcriptional regulator
C0W57_RS17990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0W57_RS17995	COG1846	Transcriptional regulator
C0W57_RS18000	COG2153	protein acetylation
C0W57_RS18010	COG0546	phosphoglycolate phosphatase activity
C0W57_RS18040	COG1404	Belongs to the peptidase S8 family
C0W57_RS18050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0W57_RS18055	COG0697	spore germination
C0W57_RS18060	COG1078	dGTPase activity
C0W57_RS18070	COG1331	Highly conserved protein containing a thioredoxin domain
C0W57_RS18075	COG1266	CAAX protease self-immunity
C0W57_RS18080	COG0477	Major facilitator Superfamily
C0W57_RS18080	COG2814	Major facilitator Superfamily
C0W57_RS18085	COG0346	lactoylglutathione lyase activity
C0W57_RS18090	COG1609	Transcriptional regulator
C0W57_RS18095	COG0708	Exodeoxyribonuclease III
C0W57_RS18100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C0W57_RS18105	COG2169	Transcriptional regulator
C0W57_RS18115	COG0629	single-stranded DNA binding
C0W57_RS18125	COG0012	GTP binding
C0W57_RS18130	COG0243	molybdopterin cofactor binding
C0W57_RS18135	COG4481	Protein conserved in bacteria
C0W57_RS18140	COG3949	Membrane
C0W57_RS18155	COG1475	DNA binding
C0W57_RS18160	COG1192	Involved in chromosome partitioning
C0W57_RS18185	COG1847	R3H domain protein
C0W57_RS18190	COG0706	membrane insertase activity
C0W57_RS18210	COG0592	DNA-directed DNA polymerase activity
C0W57_RS18215	COG2501	S4 domain
C0W57_RS18230	COG0187	DNA topoisomerase II activity
C0W57_RS18235	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C0W57_RS18270	COG0516	GMP reductase activity
C0W57_RS18270	COG0517	IMP dehydrogenase activity
C0W57_RS18275	COG1686	Belongs to the peptidase S11 family
C0W57_RS18295	COG1929	Belongs to the glycerate kinase type-1 family
C0W57_RS18305	COG1428	Deoxynucleoside kinase
C0W57_RS18310	COG1428	Deoxynucleoside kinase
C0W57_RS18315	COG3858	chitin binding
C0W57_RS18315	COG1388	LysM domain
C0W57_RS18320	COG1335	isochorismatase
C0W57_RS18325	COG0590	tRNA wobble adenosine to inosine editing
C0W57_RS18335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C0W57_RS18340	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C0W57_RS18390	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C0W57_RS18395	COG3853	Toxic anion resistance protein (TelA)
C0W57_RS18400	COG1982	Orn Lys Arg decarboxylase major
C0W57_RS18410	COG3870	Protein conserved in bacteria
C0W57_RS18415	COG1728	Protein conserved in bacteria
C0W57_RS18420	COG0470	DNA polymerase III
C0W57_RS18425	COG1774	PSP1 C-terminal conserved region
C0W57_RS18435	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C0W57_RS18445	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C0W57_RS18450	COG2002	toxin-antitoxin pair type II binding
C0W57_RS18455	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0W57_RS18455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0W57_RS18460	COG0084	hydrolase, TatD family'
C0W57_RS18465	COG3583	domain protein
C0W57_RS18465	COG3584	3D domain protein
C0W57_RS18470	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C0W57_RS18475	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C0W57_RS18485	COG4466	Protein conserved in bacteria
C0W57_RS18500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C0W57_RS18505	COG0251	oxidation-reduction process
C0W57_RS18520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C0W57_RS18540	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C0W57_RS18545	COG2002	toxin-antitoxin pair type II binding
C0W57_RS18550	COG2244	polysaccharide biosynthetic process
C0W57_RS18555	COG3956	TIGRFAM MazG family protein
C0W57_RS18560	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C0W57_RS18575	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C0W57_RS18580	COG1098	S1 RNA binding domain
C0W57_RS18595	COG2208	phosphoserine phosphatase activity
C0W57_RS18600	COG2304	oxidoreductase activity
C0W57_RS18605	COG0515	serine threonine protein kinase
C0W57_RS18615	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C0W57_RS18620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0W57_RS18635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0W57_RS18640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C0W57_RS18645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C0W57_RS18650	COG0512	Glutamine amidotransferase of anthranilate synthase
C0W57_RS18655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C0W57_RS18660	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C0W57_RS18665	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C0W57_RS18670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C0W57_RS18675	COG1396	sequence-specific DNA binding
C0W57_RS18680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C0W57_RS18685	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C0W57_RS18770	COG4463	regulation of RNA biosynthetic process
C0W57_RS18775	COG3880	PFAM UvrB UvrC protein
C0W57_RS18785	COG0542	response to heat
C0W57_RS18790	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C0W57_RS18795	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C0W57_RS18800	COG4956	integral membrane protein (PIN domain superfamily)
C0W57_RS18820	COG1045	serine acetyltransferase
C0W57_RS18830	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C0W57_RS18835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0W57_RS18840	COG3688	RNA-binding protein containing a PIN domain
C0W57_RS18845	COG1595	DNA-templated transcription, initiation
C0W57_RS18855	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C0W57_RS18860	COG0250	Participates in transcription elongation, termination and antitermination
C0W57_RS18885	COG2813	Specifically methylates the guanine in position
C0W57_RS18900	COG1358	cellular component organization or biogenesis
C0W57_RS18925	COG0596	Alpha beta hydrolase
C0W57_RS19035	COG0201	protein transport
C0W57_RS19045	COG0024	Methionine aminopeptidase
C0W57_RS19060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C0W57_RS19085	COG1122	ATPase activity
C0W57_RS19090	COG1122	ATPase activity
C0W57_RS19095	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C0W57_RS19115	COG2226	methyltransferase
C0W57_RS19120	COG2318	DinB family
C0W57_RS19130	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0W57_RS19135	COG0489	protein tyrosine kinase activity
C0W57_RS19145	COG2194	sulfuric ester hydrolase activity
C0W57_RS19150	COG0726	polysaccharide deacetylase
C0W57_RS19210	COG0738	Major facilitator superfamily
C0W57_RS19215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C0W57_RS19230	COG0659	secondary active sulfate transmembrane transporter activity
C0W57_RS19235	COG0385	Bile acid
C0W57_RS19240	COG2819	hydrolase of the alpha beta superfamily
C0W57_RS19245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0W57_RS19250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0W57_RS19255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0W57_RS19260	COG2207	Transcriptional regulator
C0W57_RS19260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0W57_RS19265	COG3876	Protein conserved in bacteria
C0W57_RS19270	COG1472	Belongs to the glycosyl hydrolase 3 family
C0W57_RS19275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C0W57_RS19280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0W57_RS19280	COG1263	PTS System
C0W57_RS19290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0W57_RS19295	COG1683	Conserved Protein
C0W57_RS19325	COG1595	DNA-templated transcription, initiation
C0W57_RS19330	COG5662	AntiSigma factor
C0W57_RS19335	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C0W57_RS19340	COG4856	YbbR-like protein
C0W57_RS19380	COG1346	cytolysis
C0W57_RS19385	COG1380	Effector of murein hydrolase LrgA
C0W57_RS19390	COG1846	Transcriptional regulator
C0W57_RS19395	COG1113	amino acid transport
C0W57_RS19400	COG1011	Hydrolase
C0W57_RS19405	COG4585	Histidine kinase
C0W57_RS19410	COG2197	response regulator
C0W57_RS19415	COG1131	(ABC) transporter
C0W57_RS19455	COG0531	amino acid
C0W57_RS19480	COG0584	glycerophosphoryl diester phosphodiesterase
C0W57_RS19485	COG2271	Major facilitator Superfamily
C0W57_RS19500	COG2368	4-hydroxyphenylacetate
C0W57_RS19510	COG3409	Peptidoglycan-binding domain 1 protein
C0W57_RS19525	COG0371	Dehydrogenase
C0W57_RS19535	COG1183	phosphatidylcholine synthase activity
C0W57_RS19540	COG0586	Pfam SNARE associated Golgi protein
C0W57_RS19545	COG0688	phosphatidylethanolamine metabolic process
C0W57_RS19560	COG1301	dicarboxylic acid transport
C0W57_RS19565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C0W57_RS19570	COG0833	amino acid
C0W57_RS19575	COG2040	homocysteine
C0W57_RS19580	COG1115	amino acid carrier protein
C0W57_RS19585	COG2066	Belongs to the glutaminase family
C0W57_RS19590	COG4191	Histidine kinase
C0W57_RS19595	COG0784	Response regulator, receiver
C0W57_RS19600	COG3173	Aminoglycoside phosphotransferase
C0W57_RS19620	COG3773	Cell wall hydrolase
C0W57_RS19630	COG3540	Alkaline phosphatase
C0W57_RS19635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0W57_RS19640	COG0805	protein transport
C0W57_RS19650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C0W57_RS19655	COG0477	Major facilitator Superfamily
C0W57_RS19660	COG1309	transcriptional regulator
C0W57_RS19665	COG0252	asparaginase activity
C0W57_RS19670	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C0W57_RS19675	COG1405	negative regulation of cell septum assembly
C0W57_RS19675	COG3012	SEC-C Motif Domain Protein
C0W57_RS19680	COG0667	Aldo Keto reductase
C0W57_RS19690	COG1595	DNA-templated transcription, initiation
C0W57_RS19695	COG1595	DNA-templated transcription, initiation
C0W57_RS19700	COG1876	peptidase activity
C0W57_RS19705	COG0457	Tetratricopeptide repeat
C0W57_RS19710	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS19715	COG0366	Alpha amylase catalytic
C0W57_RS19720	COG0803	Belongs to the bacterial solute-binding protein 9 family
C0W57_RS19725	COG1121	(ABC) transporter
C0W57_RS19730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C0W57_RS19735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0W57_RS19740	COG2310	stress, protein
C0W57_RS19745	COG2310	stress, protein
C0W57_RS19750	COG2310	stress, protein
C0W57_RS19755	COG0861	Integral membrane protein TerC family
C0W57_RS19765	COG3853	Toxic anion resistance protein (TelA)
C0W57_RS19770	COG0477	Major facilitator Superfamily
C0W57_RS19775	COG4175	Glycine betaine
C0W57_RS19775	COG0517	IMP dehydrogenase activity
C0W57_RS19780	COG4176	ABC-type proline glycine betaine transport system permease component
C0W57_RS19785	COG2113	Glycine betaine
C0W57_RS19790	COG1473	amidohydrolase
C0W57_RS19795	COG1288	antiporter activity
C0W57_RS19805	COG0366	Alpha amylase catalytic
C0W57_RS19815	COG2814	Major facilitator Superfamily
C0W57_RS19820	COG1846	Transcriptional regulator
C0W57_RS19825	COG1280	lysine exporter protein (LysE YggA)
C0W57_RS19830	COG3403	YqcI/YcgG family
C0W57_RS19835	COG1113	amino acid transport
C0W57_RS19840	COG3665	Urea carboxylase-associated protein
C0W57_RS19855	COG1660	Displays ATPase and GTPase activities
C0W57_RS19865	COG2271	Major facilitator Superfamily
C0W57_RS19870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C0W57_RS19875	COG3458	cephalosporin-C deacetylase activity
C0W57_RS19880	COG3541	Predicted nucleotidyltransferase
C0W57_RS19885	COG0506	proline dehydrogenase activity
C0W57_RS19890	COG1012	belongs to the aldehyde dehydrogenase family
C0W57_RS19895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C0W57_RS19900	COG2508	Transcriptional regulator
C0W57_RS19910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0W57_RS19910	COG1587	Uroporphyrinogen-III synthase
C0W57_RS19915	COG2146	nitrite reductase [NAD(P)H] activity
C0W57_RS19920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C0W57_RS19925	COG0243	molybdopterin cofactor binding
C0W57_RS19930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C0W57_RS19935	COG2223	nitrite transmembrane transporter activity
C0W57_RS19940	COG0523	cobalamin synthesis protein
C0W57_RS19945	COG1063	alcohol dehydrogenase
C0W57_RS19950	COG1714	RDD family
C0W57_RS19960	COG2723	6-phospho-beta-galactosidase activity
C0W57_RS19970	COG3209	COG3209 Rhs family protein
C0W57_RS19975	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C0W57_RS19980	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C0W57_RS19985	COG1733	regulation of RNA biosynthetic process
C0W57_RS19995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS20005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0W57_RS20010	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C0W57_RS20025	COG2364	Membrane
C0W57_RS20030	COG1126	abc transporter atp-binding protein
C0W57_RS20035	COG0765	amino acid transport
C0W57_RS20040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0W57_RS20045	COG0583	DNA-binding transcription factor activity
C0W57_RS20050	COG0163	prenyltransferase activity
C0W57_RS20055	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C0W57_RS20075	COG3104	oligopeptide transport
C0W57_RS20080	COG5434	Belongs to the glycosyl hydrolase 28 family
C0W57_RS20090	COG0697	spore germination
C0W57_RS20100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C0W57_RS20105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0W57_RS20110	COG0456	acetyltransferase
C0W57_RS20115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0W57_RS20120	COG0765	amino acid transport
C0W57_RS20125	COG1126	abc transporter atp-binding protein
C0W57_RS20130	COG1473	amidohydrolase
C0W57_RS20135	COG2079	MmgE PrpD family protein
C0W57_RS20140	COG1136	(ABC) transporter
C0W57_RS20145	COG0577	efflux transmembrane transporter activity
C0W57_RS20150	COG0745	RESPONSE REGULATOR receiver
C0W57_RS20155	COG3850	Histidine kinase
C0W57_RS20155	COG5002	protein histidine kinase activity
C0W57_RS20160	COG0457	Tetratricopeptide repeat
C0W57_RS20175	COG0527	aspartate kinase activity
C0W57_RS20180	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0W57_RS20185	COG4605	iron ion homeostasis
C0W57_RS20190	COG4604	ABC transporter, ATP-binding protein
C0W57_RS20195	COG4607	ABC-type enterochelin transport system periplasmic component
C0W57_RS20200	COG2814	Major facilitator Superfamily
C0W57_RS20205	COG1309	transcriptional regulator
C0W57_RS20210	COG0778	Nitroreductase
C0W57_RS20215	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C0W57_RS20220	COG0640	Transcriptional regulator
C0W57_RS20225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0W57_RS20230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C0W57_RS20235	COG1012	belongs to the aldehyde dehydrogenase family
C0W57_RS20240	COG4975	Glucose uptake
C0W57_RS20245	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS20250	COG4549	nuclear export factor GLE1
C0W57_RS20255	COG2372	response to copper ion
C0W57_RS20255	COG1276	copper resistance
C0W57_RS20260	COG1349	DNA-binding transcription factor activity
C0W57_RS20270	COG2213	PTS system mannitol-specific
C0W57_RS20275	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0W57_RS20285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C0W57_RS20295	COG0561	phosphatase activity
C0W57_RS20305	COG1914	H( )-stimulated, divalent metal cation uptake system
C0W57_RS20315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C0W57_RS20320	COG1984	allophanate hydrolase subunit 2
C0W57_RS20325	COG1414	Transcriptional regulator
C0W57_RS20330	COG2755	lipolytic protein G-D-S-L family
C0W57_RS20340	COG2329	Antibiotic biosynthesis monooxygenase
C0W57_RS20345	COG0768	penicillin binding
C0W57_RS20350	COG4989	oxidoreductase activity
C0W57_RS20355	COG3711	transcriptional antiterminator
C0W57_RS20360	COG0318	PFAM AMP-dependent synthetase and ligase
C0W57_RS20365	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS20370	COG1917	Cupin 2, conserved barrel domain protein
C0W57_RS20375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0W57_RS20380	COG3871	stress protein (general stress protein 26)
C0W57_RS20390	COG2814	Major facilitator Superfamily
C0W57_RS20395	COG1522	sequence-specific DNA binding
C0W57_RS20400	COG0551	DNA topoisomerase type I activity
C0W57_RS20400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C0W57_RS20405	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C0W57_RS20410	COG3706	GGDEF domain
C0W57_RS20415	COG5298	Protein conserved in bacteria
C0W57_RS20420	COG1215	transferase activity, transferring glycosyl groups
C0W57_RS20430	COG0531	amino acid
C0W57_RS20440	COG0028	Belongs to the TPP enzyme family
C0W57_RS20475	COG1914	H( )-stimulated, divalent metal cation uptake system
C0W57_RS20490	COG4876	unkown
C0W57_RS20500	COG2076	Multidrug Resistance protein
C0W57_RS20505	COG2217	Heavy metal translocating P-type atpase
C0W57_RS20510	COG3729	General stress protein
C0W57_RS20515	COG0662	Cupin 2, conserved barrel domain protein
C0W57_RS20520	COG2329	Antibiotic biosynthesis monooxygenase
C0W57_RS20525	COG3546	catalase activity
C0W57_RS20530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C0W57_RS20535	COG3290	protein histidine kinase activity
C0W57_RS20540	COG4565	transcriptional regulatory protein
C0W57_RS20545	COG1301	dicarboxylic acid transport
C0W57_RS20550	COG0628	permease
C0W57_RS20555	COG1131	(ABC) transporter
C0W57_RS20560	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C0W57_RS20570	COG1960	acyl-CoA dehydrogenase activity
C0W57_RS20585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C0W57_RS20590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0W57_RS20600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C0W57_RS20605	COG0513	Belongs to the DEAD box helicase family
C0W57_RS20610	COG3402	PFAM membrane-flanked domain
C0W57_RS20615	COG3428	Bacterial PH domain
C0W57_RS20620	COG0705	Rhomboid family
C0W57_RS20630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C0W57_RS20635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C0W57_RS20640	COG0864	Transcriptional regulator
C0W57_RS20645	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0W57_RS20650	COG1366	Belongs to the anti-sigma-factor antagonist family
C0W57_RS20655	COG1366	Belongs to the anti-sigma-factor antagonist family
C0W57_RS20660	COG2172	sigma factor antagonist activity
C0W57_RS20665	COG2208	phosphoserine phosphatase activity
C0W57_RS20670	COG1366	Belongs to the anti-sigma-factor antagonist family
C0W57_RS20680	COG1191	sigma factor activity
C0W57_RS20685	COG2208	phosphoserine phosphatase activity
C0W57_RS20690	COG2183	response to ionizing radiation
C0W57_RS20755	COG1959	2 iron, 2 sulfur cluster binding
C0W57_RS20780	COG2249	NAD(P)H dehydrogenase (quinone) activity
C0W57_RS20785	COG0457	Tetratricopeptide repeat
C0W57_RS20805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C0W57_RS20810	COG0477	Major facilitator Superfamily
C0W57_RS20830	COG2030	dehydratase
C0W57_RS20845	COG1959	2 iron, 2 sulfur cluster binding
C0W57_RS20850	COG2910	NAD(P)H-binding
C0W57_RS20860	COG1278	Cold shock
C0W57_RS20865	COG1329	Transcriptional regulator
C0W57_RS20870	COG1937	Protein conserved in bacteria
C0W57_RS20875	COG2210	Belongs to the sulfur carrier protein TusA family
C0W57_RS20880	COG1054	Belongs to the UPF0176 family
C0W57_RS20885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0W57_RS20885	COG0425	Belongs to the sulfur carrier protein TusA family
C0W57_RS20890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0W57_RS20890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0W57_RS20895	COG0425	Belongs to the sulfur carrier protein TusA family
C0W57_RS20900	COG0730	response to heat
C0W57_RS20905	COG1794	racemase activity, acting on amino acids and derivatives
C0W57_RS20920	COG3621	Patatin-like phospholipase
C0W57_RS20930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C0W57_RS20935	COG1802	Transcriptional regulator
C0W57_RS20940	COG0251	oxidation-reduction process
C0W57_RS20945	COG0814	amino acid
C0W57_RS20950	COG1473	amidohydrolase
C0W57_RS20955	COG1917	Cupin 2, conserved barrel domain protein
C0W57_RS20955	COG2207	Transcriptional regulator
C0W57_RS20965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0W57_RS20970	COG0477	Major facilitator Superfamily
C0W57_RS21010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0W57_RS21035	COG0351	phosphomethylpyrimidine kinase
C0W57_RS21050	COG1064	alcohol dehydrogenase
C0W57_RS21055	COG0789	Transcriptional regulator
C0W57_RS21065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0W57_RS21080	COG2814	Major facilitator Superfamily
C0W57_RS21085	COG1309	transcriptional regulator
C0W57_RS21090	COG0697	spore germination
C0W57_RS21095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0W57_RS21100	COG5577	PFAM Coat F domain
C0W57_RS21110	COG1063	alcohol dehydrogenase
C0W57_RS21115	COG5577	PFAM Coat F domain
C0W57_RS21125	COG0738	Major facilitator superfamily
C0W57_RS21140	COG4585	Histidine kinase
C0W57_RS21145	COG2197	response regulator
C0W57_RS21150	COG2409	Drug exporters of the RND superfamily
C0W57_RS21155	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C0W57_RS21160	COG0488	(ABC) transporter
C0W57_RS21165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0W57_RS21170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0W57_RS21180	COG2814	Major facilitator Superfamily
C0W57_RS21185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C0W57_RS21195	COG0730	response to heat
C0W57_RS21200	COG0456	acetyltransferase
C0W57_RS21205	COG0789	Transcriptional regulator
C0W57_RS21205	COG4978	Transcriptional regulator
C0W57_RS21210	COG0697	spore germination
C0W57_RS21215	COG1051	belongs to the nudix hydrolase family
C0W57_RS21220	COG2226	methyltransferase
C0W57_RS21225	COG0473	3-isopropylmalate dehydrogenase activity
C0W57_RS21230	COG1802	Transcriptional regulator
C0W57_RS21235	COG1819	glycosyl
C0W57_RS21250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C0W57_RS21255	COG1388	LysM domain
C0W57_RS21260	COG2814	Major facilitator Superfamily
C0W57_RS21265	COG2188	Transcriptional regulator
C0W57_RS21270	COG2186	Transcriptional regulator
C0W57_RS21275	COG2807	transmembrane transport
C0W57_RS21280	COG2076	Multidrug Resistance protein
C0W57_RS21285	COG2076	Multidrug Resistance protein
C0W57_RS21290	COG1309	transcriptional regulator
C0W57_RS21295	COG0531	amino acid
C0W57_RS21305	COG3832	glyoxalase III activity
C0W57_RS21310	COG0604	alcohol dehydrogenase
C0W57_RS21315	COG2814	Major facilitator Superfamily
C0W57_RS21355	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C0W57_RS21360	COG0802	atpase or kinase
C0W57_RS21365	COG1214	PFAM Peptidase M22, glycoprotease
C0W57_RS21370	COG0456	acetyltransferase
C0W57_RS21375	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C0W57_RS21380	COG0488	(ABC) transporter
C0W57_RS21395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0W57_RS21400	COG0805	protein transport
C0W57_RS21410	COG1266	CAAX protease self-immunity
C0W57_RS21435	COG0457	Tetratricopeptide repeat
C0W57_RS21440	COG1063	alcohol dehydrogenase
C0W57_RS21445	COG2211	Major facilitator Superfamily
C0W57_RS21450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0W57_RS21460	COG1842	Phage shock protein A
C0W57_RS21465	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C0W57_RS21470	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C0W57_RS21475	COG4260	virion core protein, lumpy skin disease virus
C0W57_RS21480	COG2755	lipolytic protein G-D-S-L family
C0W57_RS21480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C0W57_RS21490	COG1595	DNA-templated transcription, initiation
C0W57_RS21495	COG1063	alcohol dehydrogenase
C0W57_RS21500	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C0W57_RS21505	COG0823	Involved in the tonB-independent uptake of proteins
C0W57_RS21515	COG2132	Multicopper oxidase
C0W57_RS21520	COG1113	amino acid transport
C0W57_RS21525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C0W57_RS21530	COG0714	Associated with various cellular activities
C0W57_RS21535	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C0W57_RS21540	COG1305	Transglutaminase-like
C0W57_RS21550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C0W57_RS21570	COG2211	Major facilitator Superfamily
C0W57_RS21585	COG2252	PERMEase
C0W57_RS21590	COG3064	Membrane
C0W57_RS21610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C0W57_RS21615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C0W57_RS21620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C0W57_RS21625	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C0W57_RS21630	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C0W57_RS21645	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C0W57_RS21655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C0W57_RS21660	COG0138	bifunctional purine biosynthesis protein purh
C0W57_RS21665	COG0151	Belongs to the GarS family
C0W57_RS21675	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C0W57_RS21680	COG1470	cell adhesion involved in biofilm formation
C0W57_RS21685	COG4496	protein, YerC YecD
C0W57_RS21690	COG0069	glutamate synthase activity
C0W57_RS21705	COG0210	DNA helicase
C0W57_RS21715	COG4851	CamS sex pheromone cAM373 precursor
C0W57_RS21720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C0W57_RS21725	COG1285	pathogenesis
C0W57_RS21730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C0W57_RS21750	COG1309	transcriptional regulator
C0W57_RS21755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0W57_RS21760	COG1597	lipid kinase activity
C0W57_RS21765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C0W57_RS21800	COG5444	nuclease activity
C0W57_RS21830	COG3546	catalase activity
C0W57_RS21835	COG0454	-acetyltransferase
C0W57_RS21845	COG2323	membrane
C0W57_RS21850	COG2329	Antibiotic biosynthesis monooxygenase
C0W57_RS21855	COG0346	lactoylglutathione lyase activity
C0W57_RS21860	COG1366	Belongs to the anti-sigma-factor antagonist family
C0W57_RS21865	COG5583	Uncharacterized small protein (DUF2292)
C0W57_RS21870	COG0196	riboflavin kinase activity
C0W57_RS21875	COG0670	Belongs to the BI1 family
C0W57_RS21880	COG1846	Transcriptional regulator
C0W57_RS21885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0W57_RS21895	COG2124	cytochrome p450
C0W57_RS21895	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C0W57_RS21910	COG1131	(ABC) transporter
C0W57_RS21955	COG4106	trans-aconitate 2-methyltransferase activity
C0W57_RS21960	COG1368	sulfuric ester hydrolase activity
C0W57_RS21965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C0W57_RS21970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0W57_RS21975	COG1442	glycosyl transferase family 8
C0W57_RS21980	COG1216	Glycosyl transferase, family 2
C0W57_RS21985	COG1442	glycosyl transferase family 8
C0W57_RS21990	COG2223	nitrite transmembrane transporter activity
C0W57_RS21995	COG0531	amino acid
C0W57_RS22000	COG1012	belongs to the aldehyde dehydrogenase family
C0W57_RS22005	COG0840	transmembrane signaling receptor activity
C0W57_RS22010	COG1028	Short-chain dehydrogenase reductase Sdr
C0W57_RS22015	COG0463	Glycosyl transferase, family 2
C0W57_RS22015	COG0457	Tetratricopeptide repeat
C0W57_RS22020	COG0488	(ABC) transporter
C0W57_RS22025	COG0789	Transcriptional regulator
C0W57_RS22030	COG2814	Major facilitator Superfamily
C0W57_RS22035	COG0488	(ABC) transporter
C0W57_RS22040	COG0513	Belongs to the DEAD box helicase family
C0W57_RS22045	COG0456	acetyltransferase
C0W57_RS22050	COG2130	NADP-dependent
C0W57_RS22065	COG3866	Pectate lyase
C0W57_RS22070	COG0471	metal ion transport
C0W57_RS22090	COG0745	RESPONSE REGULATOR receiver
C0W57_RS22090	COG2972	Histidine kinase
C0W57_RS22095	COG3279	Response regulator of the LytR AlgR family