locus-tag	class	description
DA379_RS00010	COG0531	amino acid
DA379_RS00020	COG0028	Belongs to the TPP enzyme family
DA379_RS00050	COG1914	H( )-stimulated, divalent metal cation uptake system
DA379_RS00065	COG4876	unkown
DA379_RS00075	COG2076	Multidrug Resistance protein
DA379_RS00080	COG2217	Heavy metal translocating P-type atpase
DA379_RS00085	COG3729	General stress protein
DA379_RS00090	COG0662	Cupin 2, conserved barrel domain protein
DA379_RS00095	COG2329	Antibiotic biosynthesis monooxygenase
DA379_RS00100	COG3546	catalase activity
DA379_RS00105	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DA379_RS00110	COG3290	protein histidine kinase activity
DA379_RS00115	COG4565	transcriptional regulatory protein
DA379_RS00120	COG1301	dicarboxylic acid transport
DA379_RS00125	COG0628	permease
DA379_RS00130	COG1131	(ABC) transporter
DA379_RS00135	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DA379_RS00145	COG1960	acyl-CoA dehydrogenase activity
DA379_RS00160	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DA379_RS00165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA379_RS00175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DA379_RS00180	COG0513	Belongs to the DEAD box helicase family
DA379_RS00185	COG3402	PFAM membrane-flanked domain
DA379_RS00190	COG3428	Bacterial PH domain
DA379_RS00195	COG0705	Rhomboid family
DA379_RS00205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DA379_RS00210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DA379_RS00215	COG0864	Transcriptional regulator
DA379_RS00220	COG2337	Toxic component of a toxin-antitoxin (TA) module
DA379_RS00225	COG1366	Belongs to the anti-sigma-factor antagonist family
DA379_RS00230	COG1366	Belongs to the anti-sigma-factor antagonist family
DA379_RS00235	COG2172	sigma factor antagonist activity
DA379_RS00240	COG2208	phosphoserine phosphatase activity
DA379_RS00245	COG1366	Belongs to the anti-sigma-factor antagonist family
DA379_RS00255	COG1191	sigma factor activity
DA379_RS00260	COG2208	phosphoserine phosphatase activity
DA379_RS00265	COG2183	response to ionizing radiation
DA379_RS00315	COG2249	NAD(P)H dehydrogenase (quinone) activity
DA379_RS00330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DA379_RS00335	COG0477	Major facilitator Superfamily
DA379_RS00345	COG1764	response to oxidative stress
DA379_RS00350	COG1846	Transcriptional regulator
DA379_RS00360	COG2030	dehydratase
DA379_RS00370	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DA379_RS00375	COG1959	2 iron, 2 sulfur cluster binding
DA379_RS00380	COG2910	NAD(P)H-binding
DA379_RS00385	COG1278	Cold shock
DA379_RS00395	COG1937	Protein conserved in bacteria
DA379_RS00400	COG2210	Belongs to the sulfur carrier protein TusA family
DA379_RS00405	COG1054	Belongs to the UPF0176 family
DA379_RS00410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DA379_RS00410	COG0425	Belongs to the sulfur carrier protein TusA family
DA379_RS00415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DA379_RS00415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DA379_RS00420	COG0425	Belongs to the sulfur carrier protein TusA family
DA379_RS00425	COG0730	response to heat
DA379_RS00430	COG1794	racemase activity, acting on amino acids and derivatives
DA379_RS00445	COG3621	Patatin-like phospholipase
DA379_RS00455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DA379_RS00460	COG1802	Transcriptional regulator
DA379_RS00465	COG0251	oxidation-reduction process
DA379_RS00470	COG0814	amino acid
DA379_RS00475	COG1473	amidohydrolase
DA379_RS00480	COG2207	Transcriptional regulator
DA379_RS00480	COG1917	Cupin 2, conserved barrel domain protein
DA379_RS00490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DA379_RS00495	COG0477	Major facilitator Superfamily
DA379_RS00515	COG0277	FAD linked oxidase domain protein
DA379_RS00550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DA379_RS00575	COG1064	alcohol dehydrogenase
DA379_RS00580	COG0789	Transcriptional regulator
DA379_RS00590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DA379_RS00605	COG2814	Major facilitator Superfamily
DA379_RS00610	COG1309	transcriptional regulator
DA379_RS00620	COG5577	PFAM Coat F domain
DA379_RS00630	COG1063	alcohol dehydrogenase
DA379_RS00635	COG5577	PFAM Coat F domain
DA379_RS00645	COG4585	Histidine kinase
DA379_RS00650	COG2197	response regulator
DA379_RS00655	COG2409	Drug exporters of the RND superfamily
DA379_RS00660	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DA379_RS00665	COG0488	(ABC) transporter
DA379_RS00670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DA379_RS00675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DA379_RS00685	COG2814	Major facilitator Superfamily
DA379_RS00690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DA379_RS00700	COG0730	response to heat
DA379_RS00705	COG0456	acetyltransferase
DA379_RS00710	COG4978	Transcriptional regulator
DA379_RS00710	COG0789	Transcriptional regulator
DA379_RS00715	COG0697	spore germination
DA379_RS00720	COG1051	belongs to the nudix hydrolase family
DA379_RS00725	COG2226	methyltransferase
DA379_RS00735	COG1802	Transcriptional regulator
DA379_RS00740	COG1819	glycosyl
DA379_RS00755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DA379_RS00760	COG1388	LysM domain
DA379_RS00765	COG2814	Major facilitator Superfamily
DA379_RS00770	COG2188	Transcriptional regulator
DA379_RS00775	COG2186	Transcriptional regulator
DA379_RS00780	COG2807	transmembrane transport
DA379_RS00785	COG2076	Multidrug Resistance protein
DA379_RS00790	COG2076	Multidrug Resistance protein
DA379_RS00795	COG1309	transcriptional regulator
DA379_RS00800	COG0531	amino acid
DA379_RS00810	COG3832	glyoxalase III activity
DA379_RS00815	COG0604	alcohol dehydrogenase
DA379_RS00860	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DA379_RS00865	COG0802	atpase or kinase
DA379_RS00870	COG1214	PFAM Peptidase M22, glycoprotease
DA379_RS00875	COG0456	acetyltransferase
DA379_RS00880	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DA379_RS00900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DA379_RS00905	COG0805	protein transport
DA379_RS00915	COG1266	CAAX protease self-immunity
DA379_RS00935	COG2856	Zn peptidase
DA379_RS00945	COG1396	sequence-specific DNA binding
DA379_RS01010	COG3935	DnaD domain protein
DA379_RS01015	COG1484	DNA-dependent DNA replication
DA379_RS01110	COG1595	DNA-templated transcription, initiation
DA379_RS01125	COG5484	DNA packaging
DA379_RS01240	COG4824	toxin secretion phage lysis holin
DA379_RS01260	COG3409	Peptidoglycan-binding domain 1 protein
DA379_RS01275	COG0457	Tetratricopeptide repeat
DA379_RS01280	COG1063	alcohol dehydrogenase
DA379_RS01285	COG2211	Major facilitator Superfamily
DA379_RS01290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DA379_RS01300	COG1842	Phage shock protein A
DA379_RS01305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DA379_RS01310	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DA379_RS01315	COG4260	virion core protein, lumpy skin disease virus
DA379_RS01320	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DA379_RS01320	COG2755	lipolytic protein G-D-S-L family
DA379_RS01330	COG1595	DNA-templated transcription, initiation
DA379_RS01335	COG1063	alcohol dehydrogenase
DA379_RS01340	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DA379_RS01345	COG0823	Involved in the tonB-independent uptake of proteins
DA379_RS01355	COG2132	Multicopper oxidase
DA379_RS01360	COG1113	amino acid transport
DA379_RS01365	COG0714	Associated with various cellular activities
DA379_RS01370	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DA379_RS01375	COG1305	Transglutaminase-like
DA379_RS01395	COG2252	PERMEase
DA379_RS01400	COG3064	Membrane
DA379_RS01420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DA379_RS01425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DA379_RS01430	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DA379_RS01435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DA379_RS01440	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DA379_RS01455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DA379_RS01465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DA379_RS01470	COG0138	bifunctional purine biosynthesis protein purh
DA379_RS01475	COG0151	Belongs to the GarS family
DA379_RS01485	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DA379_RS01490	COG1470	cell adhesion involved in biofilm formation
DA379_RS01495	COG4496	protein, YerC YecD
DA379_RS01500	COG0069	glutamate synthase activity
DA379_RS01515	COG0210	DNA helicase
DA379_RS01525	COG4851	CamS sex pheromone cAM373 precursor
DA379_RS01530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DA379_RS01535	COG1285	pathogenesis
DA379_RS01540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DA379_RS01560	COG1309	transcriptional regulator
DA379_RS01565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DA379_RS01570	COG1597	lipid kinase activity
DA379_RS01575	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DA379_RS01585	COG1131	(ABC) transporter
DA379_RS01610	COG5444	nuclease activity
DA379_RS01645	COG3546	catalase activity
DA379_RS01650	COG0454	-acetyltransferase
DA379_RS01660	COG2323	membrane
DA379_RS01665	COG2329	Antibiotic biosynthesis monooxygenase
DA379_RS01670	COG0346	lactoylglutathione lyase activity
DA379_RS01675	COG1366	Belongs to the anti-sigma-factor antagonist family
DA379_RS01680	COG5583	Uncharacterized small protein (DUF2292)
DA379_RS01685	COG0196	riboflavin kinase activity
DA379_RS01690	COG0670	Belongs to the BI1 family
DA379_RS01695	COG1846	Transcriptional regulator
DA379_RS01700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DA379_RS01710	COG2124	cytochrome p450
DA379_RS01710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DA379_RS01715	COG1368	sulfuric ester hydrolase activity
DA379_RS01720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DA379_RS01725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA379_RS01730	COG1442	glycosyl transferase family 8
DA379_RS01735	COG1216	Glycosyl transferase, family 2
DA379_RS01740	COG1442	glycosyl transferase family 8
DA379_RS01745	COG2223	nitrite transmembrane transporter activity
DA379_RS01750	COG0531	amino acid
DA379_RS01755	COG1012	belongs to the aldehyde dehydrogenase family
DA379_RS01760	COG0840	transmembrane signaling receptor activity
DA379_RS01765	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS01770	COG0457	Tetratricopeptide repeat
DA379_RS01770	COG0463	Glycosyl transferase, family 2
DA379_RS01775	COG0488	(ABC) transporter
DA379_RS01780	COG0789	Transcriptional regulator
DA379_RS01785	COG2814	Major facilitator Superfamily
DA379_RS01790	COG0488	(ABC) transporter
DA379_RS01795	COG0513	Belongs to the DEAD box helicase family
DA379_RS01805	COG2130	NADP-dependent
DA379_RS01820	COG3866	Pectate lyase
DA379_RS01825	COG0471	metal ion transport
DA379_RS01845	COG3290	protein histidine kinase activity
DA379_RS01850	COG4565	transcriptional regulatory protein
DA379_RS01855	COG3181	Tripartite tricarboxylate transporter family receptor
DA379_RS01860	COG2851	Citrate transporter
DA379_RS01865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DA379_RS01870	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DA379_RS01880	COG2258	MOSC domain
DA379_RS01900	COG0024	Methionine aminopeptidase
DA379_RS01905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DA379_RS01905	COG1263	PTS System
DA379_RS01915	COG1368	sulfuric ester hydrolase activity
DA379_RS01925	COG0071	Belongs to the small heat shock protein (HSP20) family
DA379_RS01940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DA379_RS01940	COG1263	PTS System
DA379_RS01945	COG0366	Alpha amylase catalytic
DA379_RS01950	COG2188	Transcriptional regulator
DA379_RS01955	COG0778	Nitroreductase
DA379_RS01970	COG0737	Belongs to the 5'-nucleotidase family
DA379_RS01975	COG0693	protein deglycase activity
DA379_RS01980	COG1609	Transcriptional regulator
DA379_RS01995	COG2814	Major facilitator Superfamily
DA379_RS02005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DA379_RS02010	COG4980	gas vesicle protein
DA379_RS02015	COG1295	ribonuclease BN
DA379_RS02020	COG0477	Major facilitator Superfamily
DA379_RS02025	COG0387	Pfam Sodium calcium exchanger
DA379_RS02035	COG0668	transmembrane transport
DA379_RS02040	COG0535	radical SAM domain protein
DA379_RS02050	COG0726	polysaccharide deacetylase
DA379_RS02055	COG2084	Dehydrogenase
DA379_RS02065	COG0598	Magnesium transport protein CorA
DA379_RS02070	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DA379_RS02075	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DA379_RS02090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DA379_RS02095	COG4637	Psort location Cytoplasmic, score
DA379_RS02100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DA379_RS02105	COG0022	dehydrogenase e1 component
DA379_RS02110	COG0508	dehydrogenase complex catalyzes the overall conversion of
DA379_RS02115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DA379_RS02130	COG1486	melibiose metabolic process
DA379_RS02135	COG1737	Transcriptional regulator
DA379_RS02140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DA379_RS02140	COG1263	PTS System
DA379_RS02145	COG1132	(ABC) transporter
DA379_RS02150	COG1132	(ABC) transporter
DA379_RS02155	COG2259	Doxx family
DA379_RS02160	COG2514	catechol 2,3-dioxygenase activity
DA379_RS02170	COG1695	Transcriptional regulator
DA379_RS02175	COG2249	NAD(P)H dehydrogenase (quinone) activity
DA379_RS02180	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
DA379_RS02185	COG3848	Pyruvate phosphate dikinase
DA379_RS02185	COG0574	Belongs to the PEP-utilizing enzyme family
DA379_RS02190	COG2732	(Barnase) inhibitor
DA379_RS02195	COG2318	DinB family
DA379_RS02200	COG2814	Major facilitator Superfamily
DA379_RS02205	COG1846	Transcriptional regulator
DA379_RS02210	COG0392	lysyltransferase activity
DA379_RS02210	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DA379_RS02215	COG0384	phenazine biosynthesis protein PhzF
DA379_RS02220	COG0778	Nitroreductase
DA379_RS02235	COG1090	epimerase
DA379_RS02250	COG2814	Major facilitator Superfamily
DA379_RS02260	COG3591	Belongs to the peptidase S1B family
DA379_RS02275	COG3103	Sh3 type 3 domain protein
DA379_RS02280	COG5658	integral membrane protein
DA379_RS02285	COG0596	Alpha beta hydrolase
DA379_RS02290	COG0463	Glycosyl transferase, family 2
DA379_RS02295	COG4485	Bacterial membrane protein, YfhO
DA379_RS02300	COG1988	membrane-bound metal-dependent
DA379_RS02305	COG1194	a g-specific adenine glycosylase
DA379_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS02335	COG1132	(ABC) transporter
DA379_RS02340	COG4129	membrane
DA379_RS02350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DA379_RS02355	COG0735	belongs to the Fur family
DA379_RS02470	COG3340	Belongs to the peptidase S51 family
DA379_RS02480	COG0277	FAD linked oxidase domain protein
DA379_RS02490	COG0747	negative chemotaxis
DA379_RS02495	COG0601	transmembrane transport
DA379_RS02500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DA379_RS02505	COG0444	Belongs to the ABC transporter superfamily
DA379_RS02510	COG4608	Belongs to the ABC transporter superfamily
DA379_RS02515	COG0753	catalase activity
DA379_RS02525	COG1116	anion transmembrane transporter activity
DA379_RS02530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DA379_RS02535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DA379_RS02555	COG1476	TRANSCRIPTIONal
DA379_RS02565	COG3382	B3 4 domain protein
DA379_RS02570	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DA379_RS02580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DA379_RS02585	COG0789	Transcriptional regulator
DA379_RS02590	COG1664	Polymer-forming cytoskeletal
DA379_RS02595	COG1664	Polymer-forming cytoskeletal
DA379_RS02600	COG2766	serine protein kinase
DA379_RS02615	COG1846	Transcriptional regulator
DA379_RS02620	COG1566	PFAM secretion protein HlyD family protein
DA379_RS02625	COG2814	Major facilitator Superfamily
DA379_RS02630	COG0655	NAD(P)H dehydrogenase (quinone) activity
DA379_RS02645	COG1725	Transcriptional regulator
DA379_RS02650	COG1131	(ABC) transporter
DA379_RS02655	COG1131	(ABC) transporter
DA379_RS02660	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DA379_RS02665	COG1278	Cold shock
DA379_RS02675	COG1464	Belongs to the NlpA lipoprotein family
DA379_RS02680	COG3706	GGDEF domain
DA379_RS02685	COG1823	symporter activity
DA379_RS02705	COG5577	PFAM Coat F domain
DA379_RS02710	COG1525	nuclease
DA379_RS02710	COG0737	Belongs to the 5'-nucleotidase family
DA379_RS02710	COG4085	toxin activity
DA379_RS02715	COG3764	Sortase (surface protein transpeptidase)
DA379_RS02720	COG0564	pseudouridine synthase activity
DA379_RS02730	COG0517	IMP dehydrogenase activity
DA379_RS02735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DA379_RS02740	COG3153	acetyltransferase
DA379_RS02740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DA379_RS02745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DA379_RS02750	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DA379_RS02755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DA379_RS02765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DA379_RS02770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DA379_RS02785	COG0431	NADPH-dependent FMN reductase
DA379_RS02800	COG0791	NLP P60 protein
DA379_RS02800	COG1388	LysM domain
DA379_RS02805	COG1959	2 iron, 2 sulfur cluster binding
DA379_RS02810	COG0668	transmembrane transport
DA379_RS02815	COG2719	SpoVR family
DA379_RS02820	COG1785	Belongs to the alkaline phosphatase family
DA379_RS02825	COG1388	LysM domain
DA379_RS02825	COG0791	NLP P60 protein
DA379_RS02830	COG0583	DNA-binding transcription factor activity
DA379_RS02835	COG0372	Belongs to the citrate synthase family
DA379_RS02840	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS02845	COG0531	amino acid
DA379_RS02850	COG0733	neurotransmitter:sodium symporter activity
DA379_RS02865	COG1595	DNA-templated transcription, initiation
DA379_RS02870	COG0204	Acyl-transferase
DA379_RS02875	COG1253	flavin adenine dinucleotide binding
DA379_RS02880	COG0789	Transcriptional regulator
DA379_RS02885	COG0436	Aminotransferase
DA379_RS02890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DA379_RS02895	COG1253	flavin adenine dinucleotide binding
DA379_RS02900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DA379_RS02905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DA379_RS02910	COG0584	glycerophosphoryl diester phosphodiesterase
DA379_RS02920	COG0668	transmembrane transport
DA379_RS02925	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DA379_RS02930	COG0726	polysaccharide deacetylase
DA379_RS02935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DA379_RS02940	COG3226	Transcriptional regulator
DA379_RS02950	COG0589	response to stress
DA379_RS02955	COG1132	(ABC) transporter
DA379_RS02960	COG1132	(ABC) transporter
DA379_RS02965	COG0702	epimerase
DA379_RS02985	COG0189	ligase activity
DA379_RS02990	COG0189	ligase activity
DA379_RS03005	COG4335	DNA alkylation repair
DA379_RS03010	COG0561	phosphatase activity
DA379_RS03015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DA379_RS03025	COG0475	glutathione-regulated potassium exporter activity
DA379_RS03030	COG0490	domain, Protein
DA379_RS03040	COG1024	Enoyl-CoA hydratase
DA379_RS03050	COG4152	abc transporter atp-binding protein
DA379_RS03055	COG1668	transmembrane transport
DA379_RS03060	COG0420	3'-5' exonuclease activity
DA379_RS03065	COG4717	serine-type aminopeptidase activity
DA379_RS03080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DA379_RS03120	COG4980	gas vesicle protein
DA379_RS03135	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DA379_RS03140	COG0537	adenosine 5'-monophosphoramidase activity
DA379_RS03145	COG1131	(ABC) transporter
DA379_RS03150	COG4473	ABC transporter
DA379_RS03160	COG1473	amidohydrolase
DA379_RS03165	COG3069	C4-dicarboxylate transmembrane transporter activity
DA379_RS03170	COG2329	Antibiotic biosynthesis monooxygenase
DA379_RS03175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DA379_RS03185	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DA379_RS03190	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DA379_RS03195	COG1309	transcriptional regulator
DA379_RS03200	COG1511	domain protein
DA379_RS03205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DA379_RS03215	COG1363	Peptidase, m42
DA379_RS03220	COG1301	dicarboxylic acid transport
DA379_RS03230	COG1234	tRNA 3'-trailer cleavage
DA379_RS03235	COG0095	Lipoate-protein ligase
DA379_RS03240	COG0702	epimerase
DA379_RS03245	COG0318	PFAM AMP-dependent synthetase and ligase
DA379_RS03255	COG0501	Belongs to the peptidase M48B family
DA379_RS03260	COG1404	Belongs to the peptidase S8 family
DA379_RS03270	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DA379_RS03275	COG0406	alpha-ribazole phosphatase activity
DA379_RS03280	COG0183	Belongs to the thiolase family
DA379_RS03285	COG0318	PFAM AMP-dependent synthetase and ligase
DA379_RS03290	COG1268	BioY protein
DA379_RS03295	COG0840	transmembrane signaling receptor activity
DA379_RS03300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DA379_RS03300	COG0723	plastoquinol--plastocyanin reductase activity
DA379_RS03305	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS03315	COG4903	ComK protein
DA379_RS03325	COG5646	InterPro IPR014922
DA379_RS03345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DA379_RS03360	COG0398	Pfam SNARE associated Golgi protein
DA379_RS03365	COG0681	Belongs to the peptidase S26 family
DA379_RS03370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DA379_RS03375	COG1846	Transcriptional regulator
DA379_RS03380	COG3180	Ammonia monooxygenase
DA379_RS03395	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DA379_RS03400	COG2323	membrane
DA379_RS03415	COG0420	3'-5' exonuclease activity
DA379_RS03420	COG0419	ATPase involved in DNA repair
DA379_RS03425	COG1403	HNH endonuclease
DA379_RS03465	COG0179	Fumarylacetoacetate (FAA) hydrolase
DA379_RS03485	COG0367	asparagine synthase
DA379_RS03490	COG1562	ergosterol biosynthetic process
DA379_RS03495	COG0534	Mate efflux family protein
DA379_RS03500	COG2207	Transcriptional regulator
DA379_RS03500	COG1917	Cupin 2, conserved barrel domain protein
DA379_RS03505	COG1609	Transcriptional regulator
DA379_RS03510	COG0673	inositol 2-dehydrogenase activity
DA379_RS03515	COG2318	DinB family
DA379_RS03525	COG1357	PFAM Pentapeptide repeats (8 copies)
DA379_RS03530	COG2153	protein acetylation
DA379_RS03535	COG0646	methionine synthase
DA379_RS03535	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DA379_RS03545	COG2996	Protein conserved in bacteria
DA379_RS03550	COG1744	ABC transporter substrate-binding protein PnrA-like
DA379_RS03555	COG0840	transmembrane signaling receptor activity
DA379_RS03565	COG1307	EDD domain protein, DegV family
DA379_RS03570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DA379_RS03585	COG0561	phosphatase activity
DA379_RS03590	COG1073	alpha beta
DA379_RS03595	COG2151	metal-sulfur cluster biosynthetic enzyme
DA379_RS03605	COG0277	FAD linked oxidase domain protein
DA379_RS03610	COG2271	Major facilitator Superfamily
DA379_RS03620	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DA379_RS03630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DA379_RS03635	COG0505	Belongs to the CarA family
DA379_RS03645	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DA379_RS03665	COG2267	carboxylic ester hydrolase activity
DA379_RS03675	COG1744	ABC transporter substrate-binding protein PnrA-like
DA379_RS03690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DA379_RS03695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DA379_RS03700	COG5504	Zn-dependent protease
DA379_RS03705	COG0444	Belongs to the ABC transporter superfamily
DA379_RS03710	COG4608	Belongs to the ABC transporter superfamily
DA379_RS03720	COG0601	transmembrane transport
DA379_RS03725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DA379_RS03735	COG0180	Tryptophanyl-tRNA synthetase
DA379_RS03745	COG0601	transmembrane transport
DA379_RS03750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DA379_RS03755	COG0444	Belongs to the ABC transporter superfamily
DA379_RS03760	COG4608	Belongs to the ABC transporter superfamily
DA379_RS03770	COG0456	acetyltransferase
DA379_RS03775	COG1393	Belongs to the ArsC family
DA379_RS03780	COG0861	Integral membrane protein TerC family
DA379_RS03785	COG4862	establishment of competence for transformation
DA379_RS03790	COG4469	Competence protein
DA379_RS03795	COG1164	Oligoendopeptidase f
DA379_RS03800	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DA379_RS03805	COG2346	COG2346, Truncated hemoglobins
DA379_RS03810	COG0741	lytic transglycosylase activity
DA379_RS03815	COG4116	CYTH
DA379_RS03825	COG2357	RelA SpoT domain protein
DA379_RS03830	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DA379_RS03835	COG0564	pseudouridine synthase activity
DA379_RS03850	COG0569	domain protein
DA379_RS03850	COG0475	glutathione-regulated potassium exporter activity
DA379_RS03855	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DA379_RS03860	COG0352	thiamine-phosphate diphosphorylase activity
DA379_RS03865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DA379_RS03870	COG2104	thiamine diphosphate biosynthetic process
DA379_RS03880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DA379_RS03885	COG0351	phosphomethylpyrimidine kinase
DA379_RS03890	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DA379_RS03945	COG0210	DNA helicase
DA379_RS03965	COG1131	(ABC) transporter
DA379_RS03975	COG2153	protein acetylation
DA379_RS03985	COG2382	esterase
DA379_RS03990	COG0626	cystathionine gamma-synthase activity
DA379_RS03995	COG0626	cystathionine gamma-synthase activity
DA379_RS04010	COG5444	nuclease activity
DA379_RS04020	COG0346	lactoylglutathione lyase activity
DA379_RS04025	COG2367	Beta-lactamase
DA379_RS04030	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DA379_RS04040	COG1846	Transcriptional regulator
DA379_RS04050	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DA379_RS04055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DA379_RS04060	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DA379_RS04065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DA379_RS04065	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DA379_RS04070	COG1447	Phosphotransferase system cellobiose-specific component IIA
DA379_RS04080	COG1349	DNA-binding transcription factor activity
DA379_RS04095	COG1285	pathogenesis
DA379_RS04120	COG3383	formate dehydrogenase (NAD+) activity
DA379_RS04125	COG2427	Protein of unknown function (DUF1641)
DA379_RS04130	COG2124	cytochrome p450
DA379_RS04135	COG1819	glycosyl
DA379_RS04145	COG1587	Uroporphyrinogen-III synthase
DA379_RS04150	COG0390	transport system, permease component
DA379_RS04155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DA379_RS04160	COG0697	spore germination
DA379_RS04165	COG4297	protein containing double-stranded beta helix domain
DA379_RS04175	COG1252	NADH dehydrogenase
DA379_RS04185	COG2211	Major facilitator Superfamily
DA379_RS04190	COG1609	Transcriptional regulator
DA379_RS04195	COG0246	Mannitol dehydrogenase
DA379_RS04200	COG2721	sulfolactate sulfo-lyase activity
DA379_RS04205	COG0745	RESPONSE REGULATOR receiver
DA379_RS04210	COG2770	Histidine kinase
DA379_RS04210	COG2205	protein histidine kinase activity
DA379_RS04230	COG4585	Histidine kinase
DA379_RS04235	COG2197	response regulator
DA379_RS04260	COG0730	response to heat
DA379_RS04265	COG2318	DinB family
DA379_RS04270	COG0457	Tetratricopeptide repeat
DA379_RS04275	COG1388	LysM domain
DA379_RS04275	COG3409	Peptidoglycan-binding domain 1 protein
DA379_RS04275	COG5632	N-Acetylmuramoyl-L-alanine amidase
DA379_RS04290	COG2856	Zn peptidase
DA379_RS04295	COG1396	sequence-specific DNA binding
DA379_RS04305	COG1522	sequence-specific DNA binding
DA379_RS04310	COG1484	DNA-dependent DNA replication
DA379_RS04325	COG1595	DNA-templated transcription, initiation
DA379_RS04330	COG3728	DNA packaging
DA379_RS04330	COG5484	DNA packaging
DA379_RS04335	COG1783	phage Terminase large subunit
DA379_RS04340	COG5518	Phage portal protein
DA379_RS04345	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DA379_RS04350	COG4653	Phage capsid family
DA379_RS04400	COG3953	SLT domain
DA379_RS04400	COG3953	SLT domain
DA379_RS04400	COG3953	SLT domain
DA379_RS04400	COG5412	phage tail tape measure protein
DA379_RS04400	COG5412	phage tail tape measure protein
DA379_RS04400	COG5412	phage tail tape measure protein
DA379_RS04405	COG1652	LysM domain
DA379_RS04410	COG4193	domain, Protein
DA379_RS04420	COG3628	GPW Gp25 family protein
DA379_RS04425	COG3299	homolog of phage Mu protein gp47
DA379_RS04430	COG3778	Protein conserved in bacteria
DA379_RS04470	COG5632	N-Acetylmuramoyl-L-alanine amidase
DA379_RS04470	COG3409	Peptidoglycan-binding domain 1 protein
DA379_RS04485	COG0306	phosphate transporter
DA379_RS04490	COG1392	Phosphate transport regulator
DA379_RS04495	COG0531	amino acid
DA379_RS04500	COG0346	lactoylglutathione lyase activity
DA379_RS04505	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DA379_RS04510	COG0463	Glycosyl transferase, family 2
DA379_RS04515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA379_RS04520	COG0477	Major facilitator Superfamily
DA379_RS04525	COG2362	D-Aminopeptidase
DA379_RS04530	COG0601	transmembrane transport
DA379_RS04535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DA379_RS04540	COG0444	Belongs to the ABC transporter superfamily
DA379_RS04545	COG4166	transmembrane transport
DA379_RS04550	COG1619	proteins homologs of microcin C7 resistance protein MccF
DA379_RS04555	COG4948	Mandelate Racemase Muconate Lactonizing
DA379_RS04560	COG0791	NLP P60 protein
DA379_RS04565	COG4608	Belongs to the ABC transporter superfamily
DA379_RS04570	COG2706	6-phosphogluconolactonase activity
DA379_RS04575	COG1834	amidinotransferase
DA379_RS04580	COG1607	acyl-coa hydrolase
DA379_RS04585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DA379_RS04590	COG2076	Multidrug Resistance protein
DA379_RS04595	COG2076	Multidrug Resistance protein
DA379_RS04600	COG0788	formyltetrahydrofolate deformylase activity
DA379_RS04605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DA379_RS04615	COG1764	response to oxidative stress
DA379_RS04620	COG1846	Transcriptional regulator
DA379_RS04625	COG1764	response to oxidative stress
DA379_RS04640	COG0457	Tetratricopeptide repeat
DA379_RS04640	COG0463	Glycosyl transferase, family 2
DA379_RS04650	COG2814	Major facilitator Superfamily
DA379_RS04655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DA379_RS04665	COG1404	Belongs to the peptidase S8 family
DA379_RS04670	COG1366	Belongs to the anti-sigma-factor antagonist family
DA379_RS04675	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DA379_RS04680	COG1122	ATPase activity
DA379_RS04685	COG4721	ABC-type cobalt transport system, permease component
DA379_RS04690	COG3858	chitin binding
DA379_RS04690	COG1388	LysM domain
DA379_RS04710	COG2239	Acts as a magnesium transporter
DA379_RS04715	COG0789	Transcriptional regulator
DA379_RS04730	COG1846	Transcriptional regulator
DA379_RS04735	COG0726	polysaccharide deacetylase
DA379_RS04740	COG1793	dna ligase
DA379_RS04740	COG3285	dna ligase
DA379_RS04745	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DA379_RS04755	COG0586	Pfam SNARE associated Golgi protein
DA379_RS04760	COG0861	Integral membrane protein TerC family
DA379_RS04765	COG1191	sigma factor activity
DA379_RS04790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DA379_RS04795	COG2323	membrane
DA379_RS04805	COG3594	Acyltransferase
DA379_RS04810	COG5002	protein histidine kinase activity
DA379_RS04830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DA379_RS04835	COG0436	Aminotransferase
DA379_RS04865	COG3852	Histidine kinase
DA379_RS04870	COG1846	Transcriptional regulator
DA379_RS04875	COG1360	Flagellar Motor Protein
DA379_RS04880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DA379_RS04885	COG0542	response to heat
DA379_RS04895	COG3949	Membrane
DA379_RS04910	COG0720	synthase
DA379_RS04915	COG0602	queuosine metabolic process
DA379_RS04930	COG4873	Protein conserved in bacteria
DA379_RS04940	COG3773	Cell wall hydrolase
DA379_RS04945	COG2244	polysaccharide biosynthetic process
DA379_RS04950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA379_RS04955	COG2217	Heavy metal translocating P-type atpase
DA379_RS04960	COG0006	proline dipeptidase activity
DA379_RS04965	COG1609	Transcriptional regulator
DA379_RS04970	COG3711	transcriptional antiterminator
DA379_RS04975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DA379_RS04975	COG2190	(PTS) system
DA379_RS04975	COG1263	PTS System
DA379_RS04980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DA379_RS04985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DA379_RS04995	COG1533	DNA photolyase activity
DA379_RS05000	COG0840	transmembrane signaling receptor activity
DA379_RS05005	COG2084	Dehydrogenase
DA379_RS05015	COG0347	Belongs to the P(II) protein family
DA379_RS05020	COG2340	Cysteine-rich secretory protein family
DA379_RS05025	COG0768	penicillin binding
DA379_RS05030	COG4191	Histidine kinase
DA379_RS05035	COG0436	Aminotransferase
DA379_RS05045	COG0784	Response regulator, receiver
DA379_RS05045	COG0835	chemotaxis
DA379_RS05055	COG2814	Major facilitator Superfamily
DA379_RS05060	COG1376	ErfK ybiS ycfS ynhG family protein
DA379_RS05065	COG1408	metallophosphoesterase
DA379_RS05070	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS05080	COG2200	EAL domain
DA379_RS05085	COG4703	Protein of unknown function (DUF1797)
DA379_RS05090	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DA379_RS05100	COG0517	IMP dehydrogenase activity
DA379_RS05105	COG0583	DNA-binding transcription factor activity
DA379_RS05110	COG0716	FMN binding
DA379_RS05120	COG0716	FMN binding
DA379_RS05140	COG0668	transmembrane transport
DA379_RS05145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA379_RS05165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DA379_RS05170	COG0303	'Molybdopterin
DA379_RS05175	COG1763	Mo-molybdopterin cofactor biosynthetic process
DA379_RS05180	COG0314	molybdopterin synthase activity
DA379_RS05185	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DA379_RS05195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DA379_RS05200	COG1136	(ABC) transporter
DA379_RS05205	COG0577	efflux transmembrane transporter activity
DA379_RS05210	COG1349	DNA-binding transcription factor activity
DA379_RS05215	COG1105	Belongs to the carbohydrate kinase PfkB family
DA379_RS05220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DA379_RS05220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DA379_RS05220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DA379_RS05225	COG0681	Belongs to the peptidase S26 family
DA379_RS05235	COG0488	(ABC) transporter
DA379_RS05240	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DA379_RS05245	COG2309	aminopeptidase activity
DA379_RS05255	COG1077	Cell shape determining protein MreB Mrl
DA379_RS05265	COG2002	toxin-antitoxin pair type II binding
DA379_RS05270	COG3852	Histidine kinase
DA379_RS05275	COG2105	PFAM AIG2 family protein
DA379_RS05275	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DA379_RS05280	COG0569	domain protein
DA379_RS05290	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DA379_RS05300	COG0561	phosphatase activity
DA379_RS05305	COG0242	peptide deformylase activity
DA379_RS05315	COG0497	DNA recombination
DA379_RS05340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS05340	COG3321	synthase
DA379_RS05340	COG4221	oxidoreductase activity
DA379_RS05340	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS05345	COG0300	oxidoreductase activity
DA379_RS05345	COG4221	oxidoreductase activity
DA379_RS05345	COG3321	synthase
DA379_RS05345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA379_RS05350	COG0300	oxidoreductase activity
DA379_RS05350	COG3321	synthase
DA379_RS05350	COG4221	oxidoreductase activity
DA379_RS05350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA379_RS05355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA379_RS05355	COG3321	synthase
DA379_RS05355	COG0300	oxidoreductase activity
DA379_RS05355	COG4221	oxidoreductase activity
DA379_RS05360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS05360	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS05360	COG3321	synthase
DA379_RS05360	COG4221	oxidoreductase activity
DA379_RS05365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DA379_RS05370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DA379_RS05375	COG0022	dehydrogenase e1 component
DA379_RS05380	COG0508	dehydrogenase complex catalyzes the overall conversion of
DA379_RS05385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DA379_RS05390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA379_RS05405	COG1982	Orn Lys Arg decarboxylase major
DA379_RS05430	COG0483	inositol monophosphate 1-phosphatase activity
DA379_RS05440	COG3227	Zinc metalloprotease (Elastase)
DA379_RS05465	COG1217	gtp-binding protein TYPA
DA379_RS05475	COG4896	Protein conserved in bacteria
DA379_RS05485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DA379_RS05490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DA379_RS05495	COG2066	Belongs to the glutaminase family
DA379_RS05505	COG0772	Belongs to the SEDS family
DA379_RS05510	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DA379_RS05525	COG2010	Cytochrome c
DA379_RS05525	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DA379_RS05530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DA379_RS05535	COG1845	cytochrome c oxidase, subunit III
DA379_RS05540	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DA379_RS05545	COG3336	cytochrome c oxidase
DA379_RS05555	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DA379_RS05560	COG2340	Cysteine-rich secretory protein family
DA379_RS05575	COG3679	Belongs to the UPF0342 family
DA379_RS05590	COG0742	ribosomal rna small subunit methyltransferase
DA379_RS05600	COG3314	Sporulation integral membrane protein YlbJ
DA379_RS05605	COG1752	Esterase of the alpha-beta hydrolase superfamily
DA379_RS05610	COG3480	Lon protease (S16) C-terminal proteolytic domain
DA379_RS05620	COG1399	metal-binding, possibly nucleic acid-binding protein
DA379_RS05640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DA379_RS05660	COG4839	cell division protein FtsL
DA379_RS05665	COG0768	penicillin binding
DA379_RS05670	COG0768	penicillin binding
DA379_RS05690	COG0772	Belongs to the SEDS family
DA379_RS05705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DA379_RS05710	COG0849	cell division
DA379_RS05715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DA379_RS05720	COG1404	Belongs to the peptidase S8 family
DA379_RS05720	COG4412	M6 family metalloprotease domain protein
DA379_RS05730	COG1191	sigma factor activity
DA379_RS05735	COG1191	sigma factor activity
DA379_RS05740	COG1119	ATPase activity
DA379_RS05745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DA379_RS05750	COG1873	PFAM PRC-barrel domain
DA379_RS05755	COG1496	oxidoreductase activity
DA379_RS05760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DA379_RS05770	COG0762	integral membrane protein
DA379_RS05775	COG2302	S4 RNA-binding domain
DA379_RS05780	COG3599	regulation of cell shape
DA379_RS05790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DA379_RS05795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DA379_RS05805	COG0564	pseudouridine synthase activity
DA379_RS05815	COG2233	PERMEase
DA379_RS05825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DA379_RS05830	COG0505	Belongs to the CarA family
DA379_RS05835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DA379_RS05850	COG0284	orotidine-5'-phosphate decarboxylase activity
DA379_RS05855	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DA379_RS05865	COG0306	phosphate transporter
DA379_RS05880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DA379_RS05885	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
DA379_RS05890	COG1648	precorrin-2 dehydrogenase activity
DA379_RS05905	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DA379_RS05910	COG1561	YicC-like family, N-terminal region
DA379_RS05920	COG0194	GDP metabolic process
DA379_RS05930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DA379_RS05935	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DA379_RS05940	COG0242	peptide deformylase activity
DA379_RS05950	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DA379_RS05950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DA379_RS05960	COG0631	protein serine/threonine phosphatase activity
DA379_RS05965	COG2815	serine threonine protein kinase
DA379_RS05965	COG0515	serine threonine protein kinase
DA379_RS05975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DA379_RS05980	COG1564	THIamine pyrophosphokinase
DA379_RS05995	COG1302	Protein conserved in bacteria
DA379_RS06000	COG1461	Dihydroxyacetone kinase
DA379_RS06005	COG1760	l-serine dehydratase
DA379_RS06010	COG1760	l-serine dehydratase
DA379_RS06015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DA379_RS06030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DA379_RS06035	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS06050	COG1196	nuclear chromosome segregation
DA379_RS06055	COG0552	protein localization to endoplasmic reticulum
DA379_RS06070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DA379_RS06080	COG1837	Belongs to the UPF0109 family
DA379_RS06105	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DA379_RS06120	COG2257	FlhB HrpN YscU SpaS Family
DA379_RS06130	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DA379_RS06135	COG0758	DNA mediated transformation
DA379_RS06140	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DA379_RS06150	COG4974	Belongs to the 'phage' integrase family
DA379_RS06170	COG1815	bacterial-type flagellum-dependent cell motility
DA379_RS06175	COG1558	bacterial-type flagellum-dependent cell motility
DA379_RS06180	COG1677	Flagellar hook-basal body complex protein FliE
DA379_RS06185	COG1766	The M ring may be actively involved in energy transduction
DA379_RS06190	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DA379_RS06195	COG1317	bacterial-type flagellum organization
DA379_RS06200	COG1157	protein secretion by the type III secretion system
DA379_RS06205	COG2882	bacterial-type flagellum organization
DA379_RS06210	COG3334	PFAM MgtE intracellular
DA379_RS06215	COG3144	bacterial-type flagellum assembly
DA379_RS06220	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DA379_RS06225	COG4786	Flagellar basal body rod
DA379_RS06230	COG1582	Flagellar protein (FlbD)
DA379_RS06235	COG1580	Controls the rotational direction of flagella during chemotaxis
DA379_RS06240	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DA379_RS06245	COG1776	CheC inhibitor of MCP methylation
DA379_RS06245	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DA379_RS06250	COG2201	protein-glutamate methylesterase activity
DA379_RS06255	COG3190	flagellar
DA379_RS06260	COG1338	Plays a role in the flagellum-specific transport system
DA379_RS06265	COG1987	bacterial-type flagellum assembly
DA379_RS06270	COG1684	flagellar biosynthetic protein fliR
DA379_RS06275	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DA379_RS06280	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DA379_RS06285	COG1419	protein localization to endoplasmic reticulum
DA379_RS06290	COG0455	bacterial-type flagellum organization
DA379_RS06295	COG2201	protein-glutamate methylesterase activity
DA379_RS06300	COG2198	Histidine kinase
DA379_RS06300	COG0643	Histidine kinase
DA379_RS06305	COG0835	chemotaxis
DA379_RS06310	COG1776	CheC inhibitor of MCP methylation
DA379_RS06320	COG1191	sigma factor activity
DA379_RS06350	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DA379_RS06355	COG4589	Belongs to the CDS family
DA379_RS06365	COG0750	zinc metalloprotease
DA379_RS06375	COG2176	DNA-directed DNA polymerase activity
DA379_RS06385	COG0195	Participates in both transcription termination and antitermination
DA379_RS06390	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DA379_RS06395	COG1358	cellular component organization or biogenesis
DA379_RS06405	COG1550	Protein conserved in bacteria
DA379_RS06420	COG0196	riboflavin kinase activity
DA379_RS06435	COG0726	polysaccharide deacetylase
DA379_RS06440	COG0612	Peptidase, M16
DA379_RS06445	COG1873	PFAM PRC-barrel domain
DA379_RS06450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DA379_RS06455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DA379_RS06460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DA379_RS06465	COG0527	aspartate kinase activity
DA379_RS06475	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DA379_RS06480	COG0740	serine-type endopeptidase activity
DA379_RS06490	COG1674	ftsk spoiiie
DA379_RS06490	COG4980	gas vesicle protein
DA379_RS06495	COG2188	Transcriptional regulator
DA379_RS06500	COG2814	Major facilitator Superfamily
DA379_RS06505	COG1846	Transcriptional regulator
DA379_RS06510	COG1033	growth of symbiont in host cell
DA379_RS06510	COG2409	Drug exporters of the RND superfamily
DA379_RS06515	COG0612	Peptidase, M16
DA379_RS06520	COG0612	Peptidase, M16
DA379_RS06525	COG0300	oxidoreductase activity
DA379_RS06540	COG1426	Protein conserved in bacteria
DA379_RS06545	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DA379_RS06560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DA379_RS06570	COG1692	metallophosphoesterase
DA379_RS06575	COG2359	stage V sporulation protein S
DA379_RS06595	COG4550	Control of competence regulator ComK, YlbF/YmcA
DA379_RS06645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA379_RS06650	COG3425	synthase
DA379_RS06655	COG1024	Enoyl-CoA hydratase
DA379_RS06660	COG1024	Enoyl-CoA hydratase
DA379_RS06665	COG3321	synthase
DA379_RS06665	COG0300	oxidoreductase activity
DA379_RS06665	COG0318	PFAM AMP-dependent synthetase and ligase
DA379_RS06665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS06665	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS06670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA379_RS06670	COG0300	oxidoreductase activity
DA379_RS06670	COG3321	synthase
DA379_RS06670	COG4221	oxidoreductase activity
DA379_RS06675	COG3321	synthase
DA379_RS06675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA379_RS06675	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS06675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA379_RS06675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA379_RS06675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA379_RS06675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS06675	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS06675	COG3321	synthase
DA379_RS06675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS06680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS06680	COG3321	synthase
DA379_RS06680	COG4221	oxidoreductase activity
DA379_RS06685	COG3321	synthase
DA379_RS06685	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DA379_RS06685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DA379_RS06685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA379_RS06690	COG2124	cytochrome p450
DA379_RS06695	COG3209	COG3209 Rhs family protein
DA379_RS06700	COG3619	membrane
DA379_RS06710	COG1404	Belongs to the peptidase S8 family
DA379_RS06720	COG4195	phage-related replication protein
DA379_RS06725	COG1764	response to oxidative stress
DA379_RS06735	COG2076	Multidrug Resistance protein
DA379_RS06775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DA379_RS06780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DA379_RS06785	COG4112	unkown
DA379_RS06790	COG0860	N-Acetylmuramoyl-L-alanine amidase
DA379_RS06805	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DA379_RS06810	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DA379_RS06815	COG0789	Transcriptional regulator
DA379_RS06820	COG0174	glutamine synthetase
DA379_RS06830	COG2211	Major facilitator Superfamily
DA379_RS06835	COG3507	Belongs to the glycosyl hydrolase 43 family
DA379_RS06850	COG1070	Carbohydrate kinase
DA379_RS06855	COG3848	Pyruvate phosphate dikinase
DA379_RS06855	COG0574	Belongs to the PEP-utilizing enzyme family
DA379_RS06880	COG1064	alcohol dehydrogenase
DA379_RS06910	COG3397	chitin binding
DA379_RS06920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DA379_RS06935	COG5434	Belongs to the glycosyl hydrolase 28 family
DA379_RS06940	COG0756	dUTP diphosphatase activity
DA379_RS06945	COG4195	phage-related replication protein
DA379_RS06975	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DA379_RS06985	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DA379_RS07005	COG0785	Cytochrome C biogenesis protein
DA379_RS07010	COG2201	protein-glutamate methylesterase activity
DA379_RS07015	COG4846	Membrane protein involved in cytochrome C biogenesis
DA379_RS07025	COG0071	Belongs to the small heat shock protein (HSP20) family
DA379_RS07040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DA379_RS07045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA379_RS07065	COG0824	Thioesterase
DA379_RS07075	COG4841	protein insertion into membrane
DA379_RS07085	COG1832	CoA-binding protein
DA379_RS07090	COG0187	DNA topoisomerase II activity
DA379_RS07095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DA379_RS07105	COG1115	amino acid carrier protein
DA379_RS07115	COG1063	alcohol dehydrogenase
DA379_RS07120	COG0800	Aldolase
DA379_RS07130	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS07135	COG1609	Transcriptional regulator
DA379_RS07140	COG2271	Major facilitator Superfamily
DA379_RS07175	COG2205	protein histidine kinase activity
DA379_RS07180	COG0745	RESPONSE REGULATOR receiver
DA379_RS07190	COG3507	Belongs to the glycosyl hydrolase 43 family
DA379_RS07220	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS07225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DA379_RS07230	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DA379_RS07235	COG2610	gluconate transmembrane transporter activity
DA379_RS07240	COG2124	cytochrome p450
DA379_RS07260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DA379_RS07270	COG2246	polysaccharide biosynthetic process
DA379_RS07275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DA379_RS07280	COG0586	Pfam SNARE associated Golgi protein
DA379_RS07285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DA379_RS07290	COG1024	Enoyl-CoA hydratase
DA379_RS07295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DA379_RS07300	COG0511	ligase activity, forming carbon-carbon bonds
DA379_RS07305	COG0439	Biotin carboxylase
DA379_RS07310	COG0318	PFAM AMP-dependent synthetase and ligase
DA379_RS07315	COG1960	acyl-CoA dehydrogenase activity
DA379_RS07320	COG1649	PFAM Uncharacterised BCR, COG1649
DA379_RS07330	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DA379_RS07330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS07335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS07340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS07345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS07350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS07360	COG2027	D-alanyl-D-alanine carboxypeptidase
DA379_RS07365	COG2017	converts alpha-aldose to the beta-anomer
DA379_RS07370	COG0534	Mate efflux family protein
DA379_RS07385	COG0582	viral genome integration into host DNA
DA379_RS07390	COG0166	Belongs to the GPI family
DA379_RS07395	COG0405	Gamma-glutamyltransferase
DA379_RS07400	COG2814	Major facilitator Superfamily
DA379_RS07405	COG0640	Transcriptional regulator
DA379_RS07430	COG0493	'glutamate synthase
DA379_RS07435	COG0070	glutamate synthase
DA379_RS07435	COG0069	glutamate synthase activity
DA379_RS07435	COG0067	glutamate synthase
DA379_RS07440	COG0583	DNA-binding transcription factor activity
DA379_RS07445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DA379_RS07460	COG0300	oxidoreductase activity
DA379_RS07465	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DA379_RS07475	COG2814	Major facilitator Superfamily
DA379_RS07480	COG1070	Carbohydrate kinase
DA379_RS07485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DA379_RS07490	COG0243	molybdopterin cofactor binding
DA379_RS07515	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS07520	COG1733	regulation of RNA biosynthetic process
DA379_RS07525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DA379_RS07530	COG2207	Transcriptional regulator
DA379_RS07530	COG0662	Cupin 2, conserved barrel domain protein
DA379_RS07535	COG1309	transcriptional regulator
DA379_RS07540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DA379_RS07550	COG0640	Transcriptional regulator
DA379_RS07555	COG0741	lytic transglycosylase activity
DA379_RS07560	COG2322	membrane
DA379_RS07575	COG1619	proteins homologs of microcin C7 resistance protein MccF
DA379_RS07585	COG3584	3D domain protein
DA379_RS07585	COG1388	LysM domain
DA379_RS07590	COG0514	ATP-dependent DNA helicase (RecQ)
DA379_RS07600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DA379_RS07605	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DA379_RS07620	COG0071	Belongs to the small heat shock protein (HSP20) family
DA379_RS07650	COG1012	belongs to the aldehyde dehydrogenase family
DA379_RS07655	COG1657	PFAM Prenyltransferase squalene oxidase
DA379_RS07660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DA379_RS07665	COG0733	neurotransmitter:sodium symporter activity
DA379_RS07670	COG0385	Bile acid
DA379_RS07675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DA379_RS07680	COG0508	dehydrogenase complex catalyzes the overall conversion of
DA379_RS07690	COG4548	von Willebrand factor, type A
DA379_RS07695	COG0714	Associated with various cellular activities
DA379_RS07700	COG2032	superoxide dismutase activity
DA379_RS07705	COG1388	LysM domain
DA379_RS07705	COG0791	NLP P60 protein
DA379_RS07710	COG1819	glycosyl
DA379_RS07715	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DA379_RS07720	COG0534	Mate efflux family protein
DA379_RS07725	COG1366	Belongs to the anti-sigma-factor antagonist family
DA379_RS07730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DA379_RS07735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DA379_RS07745	COG2962	Rard protein
DA379_RS07760	COG1942	4-Oxalocrotonate Tautomerase
DA379_RS07770	COG1733	regulation of RNA biosynthetic process
DA379_RS07775	COG0778	Nitroreductase
DA379_RS07780	COG0400	carboxylic ester hydrolase activity
DA379_RS07785	COG0346	lactoylglutathione lyase activity
DA379_RS07795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DA379_RS07805	COG2723	6-phospho-beta-galactosidase activity
DA379_RS07810	COG2188	Transcriptional regulator
DA379_RS07815	COG3409	Peptidoglycan-binding domain 1 protein
DA379_RS07815	COG0793	Belongs to the peptidase S41A family
DA379_RS07820	COG2226	methyltransferase
DA379_RS07830	COG1876	peptidase activity
DA379_RS07850	COG0671	phosphoesterase, PA-phosphatase related
DA379_RS07885	COG1509	lysine 2,3-aminomutase activity
DA379_RS07890	COG0456	acetyltransferase
DA379_RS07895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DA379_RS07900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DA379_RS07905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DA379_RS07910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DA379_RS07930	COG0456	acetyltransferase
DA379_RS07935	COG0463	Glycosyl transferase, family 2
DA379_RS07950	COG4641	Protein conserved in bacteria
DA379_RS07960	COG1086	Polysaccharide biosynthesis protein
DA379_RS07995	COG1388	LysM domain
DA379_RS08000	COG0457	Tetratricopeptide repeat
DA379_RS08025	COG5444	nuclease activity
DA379_RS08030	COG4282	regulation of fungal-type cell wall biogenesis
DA379_RS08035	COG1525	nuclease
DA379_RS08050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DA379_RS08070	COG1846	Transcriptional regulator
DA379_RS08075	COG4698	Protein conserved in bacteria
DA379_RS08080	COG2755	lipolytic protein G-D-S-L family
DA379_RS08085	COG1999	signal sequence binding
DA379_RS08095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DA379_RS08100	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DA379_RS08105	COG1272	protein, Hemolysin III
DA379_RS08110	COG0204	Acyl-transferase
DA379_RS08115	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DA379_RS08130	COG2136	Putative SAM-dependent methyltransferase
DA379_RS08130	COG2521	methyltransferase
DA379_RS08145	COG1413	lyase activity
DA379_RS08150	COG1418	mRNA catabolic process
DA379_RS08155	COG0386	Belongs to the glutathione peroxidase family
DA379_RS08165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DA379_RS08170	COG1278	Cold shock
DA379_RS08190	COG0328	RNA-DNA hybrid ribonuclease activity
DA379_RS08195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DA379_RS08200	COG0328	RNA-DNA hybrid ribonuclease activity
DA379_RS08210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DA379_RS08225	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DA379_RS08235	COG1755	Isoprenylcysteine carboxyl methyltransferase
DA379_RS08240	COG3424	synthase
DA379_RS08265	COG1335	isochorismatase
DA379_RS08275	COG2233	PERMEase
DA379_RS08285	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DA379_RS08290	COG1199	ATP-dependent helicase activity
DA379_RS08310	COG0116	Belongs to the methyltransferase superfamily
DA379_RS08335	COG3359	exonuclease
DA379_RS08340	COG1205	dead DEAH box helicase
DA379_RS08340	COG1111	helicase
DA379_RS08345	COG2190	(PTS) system
DA379_RS08350	COG0071	Belongs to the small heat shock protein (HSP20) family
DA379_RS08390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DA379_RS08390	COG4499	WXG100 protein secretion system (Wss), protein YukC
DA379_RS08400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DA379_RS08405	COG3935	DnaD domain protein
DA379_RS08415	COG0436	Aminotransferase
DA379_RS08420	COG5353	protein conserved in bacteria
DA379_RS08430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DA379_RS08430	COG1199	ATP-dependent helicase activity
DA379_RS08460	COG0438	transferase activity, transferring glycosyl groups
DA379_RS08465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DA379_RS08480	COG1694	Mazg nucleotide pyrophosphohydrolase
DA379_RS08485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DA379_RS08490	COG2140	Oxalate decarboxylase
DA379_RS08500	COG4347	Protein of unknown function (DUF1405)
DA379_RS08505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DA379_RS08505	COG2010	Cytochrome c
DA379_RS08510	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DA379_RS08530	COG0457	Tetratricopeptide repeat
DA379_RS08540	COG0287	Prephenate dehydrogenase
DA379_RS08575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DA379_RS08580	COG4401	Chorismate mutase type I
DA379_RS08595	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DA379_RS08600	COG0105	UTP biosynthetic process
DA379_RS08605	COG0142	geranyltranstransferase activity
DA379_RS08615	COG0142	geranyltranstransferase activity
DA379_RS08630	COG0776	regulation of translation
DA379_RS08635	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DA379_RS08675	COG0539	negative regulation of cytoplasmic translation
DA379_RS08685	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DA379_RS08690	COG2959	enzyme of heme biosynthesis
DA379_RS08695	COG3773	Cell wall hydrolase
DA379_RS08695	COG3409	Peptidoglycan-binding domain 1 protein
DA379_RS08700	COG2339	peptidase activity
DA379_RS08705	COG0492	ferredoxin-NADP+ reductase activity
DA379_RS08710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DA379_RS08715	COG4862	establishment of competence for transformation
DA379_RS08720	COG1408	metallophosphoesterase
DA379_RS08730	COG1388	LysM domain
DA379_RS08735	COG1266	CAAX protease self-immunity
DA379_RS08740	COG0514	ATP-dependent DNA helicase (RecQ)
DA379_RS08745	COG4955	Helix-turn-helix domain
DA379_RS08750	COG1141	Ferredoxin
DA379_RS08755	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DA379_RS08760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DA379_RS08770	COG1595	DNA-templated transcription, initiation
DA379_RS08775	COG5002	protein histidine kinase activity
DA379_RS08780	COG0745	RESPONSE REGULATOR receiver
DA379_RS08785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DA379_RS08790	COG1333	cytochrome c biogenesis protein
DA379_RS08795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA379_RS08800	COG1187	pseudouridine synthase activity
DA379_RS08805	COG0700	Nucleoside recognition
DA379_RS08810	COG2715	membrane protein required for spore maturation
DA379_RS08815	COG1686	Belongs to the peptidase S11 family
DA379_RS08840	COG1547	Domain of unknown function (DUF309)
DA379_RS08850	COG0456	acetyltransferase
DA379_RS08865	COG0307	riboflavin synthase, alpha
DA379_RS08870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DA379_RS08870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DA379_RS08880	COG0681	Belongs to the peptidase S26 family
DA379_RS08890	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DA379_RS08895	COG4086	secreted protein
DA379_RS08900	COG0019	diaminopimelate decarboxylase activity
DA379_RS08905	COG0697	spore germination
DA379_RS08940	COG1191	sigma factor activity
DA379_RS08950	COG1366	Belongs to the anti-sigma-factor antagonist family
DA379_RS08955	COG1686	Belongs to the peptidase S11 family
DA379_RS08960	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DA379_RS08965	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DA379_RS08970	COG4974	Belongs to the 'phage' integrase family
DA379_RS08980	COG0735	belongs to the Fur family
DA379_RS08985	COG1300	Membrane
DA379_RS09000	COG0281	malic enzyme
DA379_RS09005	COG1757	Na H antiporter
DA379_RS09010	COG1027	Aspartate ammonia-lyase
DA379_RS09015	COG0252	asparaginase activity
DA379_RS09020	COG1396	sequence-specific DNA binding
DA379_RS09025	COG1379	DNA repair
DA379_RS09030	COG0494	nUDIX hydrolase
DA379_RS09040	COG0667	Aldo Keto reductase
DA379_RS09050	COG1073	alpha beta
DA379_RS09060	COG4918	Iron-sulphur cluster biosynthesis
DA379_RS09065	COG0456	acetyltransferase
DA379_RS09065	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DA379_RS09070	COG2329	Antibiotic biosynthesis monooxygenase
DA379_RS09075	COG0456	acetyltransferase
DA379_RS09080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DA379_RS09105	COG0346	lactoylglutathione lyase activity
DA379_RS09115	COG3048	D-serine ammonia-lyase activity
DA379_RS09120	COG0300	oxidoreductase activity
DA379_RS09125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DA379_RS09130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DA379_RS09135	COG1024	Enoyl-CoA hydratase
DA379_RS09140	COG3425	synthase
DA379_RS09145	COG2124	cytochrome p450
DA379_RS09155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA379_RS09155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA379_RS09155	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS09155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS09155	COG3321	synthase
DA379_RS09160	COG0318	PFAM AMP-dependent synthetase and ligase
DA379_RS09160	COG0300	oxidoreductase activity
DA379_RS09160	COG3321	synthase
DA379_RS09160	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS09160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS09165	COG0300	oxidoreductase activity
DA379_RS09165	COG0318	PFAM AMP-dependent synthetase and ligase
DA379_RS09165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS09165	COG3321	synthase
DA379_RS09170	COG3321	synthase
DA379_RS09170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS09170	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS09170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA379_RS09170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA379_RS09175	COG3321	synthase
DA379_RS09175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS09175	COG0318	PFAM AMP-dependent synthetase and ligase
DA379_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS09175	COG0300	oxidoreductase activity
DA379_RS09180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS09180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DA379_RS09180	COG3321	synthase
DA379_RS09180	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS09180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA379_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS09190	COG0318	PFAM AMP-dependent synthetase and ligase
DA379_RS09205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DA379_RS09205	COG2070	2-Nitropropane dioxygenase
DA379_RS09215	COG0250	Participates in transcription elongation, termination and antitermination
DA379_RS09240	COG0596	Alpha beta hydrolase
DA379_RS09255	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DA379_RS09260	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DA379_RS09275	COG0706	membrane insertase activity
DA379_RS09280	COG2195	Cleaves the N-terminal amino acid of tripeptides
DA379_RS09285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DA379_RS09290	COG0346	lactoylglutathione lyase activity
DA379_RS09295	COG1376	ErfK ybiS ycfS ynhG family protein
DA379_RS09300	COG4129	membrane
DA379_RS09305	COG1126	abc transporter atp-binding protein
DA379_RS09310	COG0765	amino acid transport
DA379_RS09315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DA379_RS09325	COG1597	lipid kinase activity
DA379_RS09330	COG0508	dehydrogenase complex catalyzes the overall conversion of
DA379_RS09335	COG0022	dehydrogenase e1 component
DA379_RS09340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DA379_RS09345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DA379_RS09350	COG3426	butyrate kinase activity
DA379_RS09355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DA379_RS09360	COG0280	phosphate acetyltransferase
DA379_RS09365	COG3829	transcription factor binding
DA379_RS09365	COG3290	protein histidine kinase activity
DA379_RS09375	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DA379_RS09380	COG2079	MmgE PrpD family protein
DA379_RS09385	COG0372	Belongs to the citrate synthase family
DA379_RS09390	COG1960	acyl-CoA dehydrogenase activity
DA379_RS09395	COG1250	3-hydroxyacyl-CoA dehydrogenase
DA379_RS09400	COG0183	Belongs to the thiolase family
DA379_RS09405	COG0584	glycerophosphoryl diester phosphodiesterase
DA379_RS09410	COG0860	N-Acetylmuramoyl-L-alanine amidase
DA379_RS09430	COG1902	pentaerythritol trinitrate reductase activity
DA379_RS09445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DA379_RS09450	COG0745	RESPONSE REGULATOR receiver
DA379_RS09455	COG0750	zinc metalloprotease
DA379_RS09460	COG0497	DNA recombination
DA379_RS09470	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DA379_RS09480	COG0142	geranyltranstransferase activity
DA379_RS09490	COG1570	exodeoxyribonuclease VII activity
DA379_RS09505	COG1302	Protein conserved in bacteria
DA379_RS09510	COG0439	Biotin carboxylase
DA379_RS09515	COG0511	ligase activity, forming carbon-carbon bonds
DA379_RS09555	COG3854	ATPases associated with a variety of cellular activities
DA379_RS09570	COG0006	proline dipeptidase activity
DA379_RS09580	COG3872	metal-dependent enzyme
DA379_RS09590	COG1752	Esterase of the alpha-beta hydrolase superfamily
DA379_RS09605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DA379_RS09625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DA379_RS09640	COG1396	sequence-specific DNA binding
DA379_RS09650	COG0681	Belongs to the peptidase S26 family
DA379_RS09675	COG4940	Competence protein ComGF
DA379_RS09685	COG4970	Tfp pilus assembly protein FimT
DA379_RS09690	COG4537	Required for transformation and DNA binding
DA379_RS09695	COG1459	type II secretion system
DA379_RS09700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DA379_RS09705	COG0598	Magnesium transport protein CorA
DA379_RS09710	COG1253	flavin adenine dinucleotide binding
DA379_RS09715	COG1366	Belongs to the anti-sigma-factor antagonist family
DA379_RS09725	COG1393	Belongs to the ArsC family
DA379_RS09735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DA379_RS09745	COG0011	TIGRFAM Protein of
DA379_RS09755	COG2866	Carboxypeptidase
DA379_RS09760	COG1940	carbohydrate kinase activity
DA379_RS09765	COG4483	Protein conserved in bacteria
DA379_RS09770	COG1757	Na H antiporter
DA379_RS09780	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DA379_RS09795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DA379_RS09800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DA379_RS09805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DA379_RS09810	COG0581	inorganic phosphate transmembrane transporter activity
DA379_RS09815	COG0573	inorganic phosphate transmembrane transporter activity
DA379_RS09820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DA379_RS09825	COG0768	penicillin binding
DA379_RS09830	COG0477	Major facilitator Superfamily
DA379_RS09835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DA379_RS09840	COG2839	Protein conserved in bacteria
DA379_RS09845	COG5521	maltodextrose utilization protein MalA
DA379_RS09850	COG1388	LysM domain
DA379_RS09860	COG4709	membrane
DA379_RS09865	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
DA379_RS09870	COG0735	belongs to the Fur family
DA379_RS09875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DA379_RS09890	COG0513	Belongs to the DEAD box helicase family
DA379_RS09905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DA379_RS09910	COG2384	SAM-dependent methyltransferase
DA379_RS09915	COG2010	Cytochrome c
DA379_RS09920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DA379_RS09925	COG0358	DNA primase activity
DA379_RS09940	COG0517	IMP dehydrogenase activity
DA379_RS09945	COG0751	glycine-tRNA ligase activity
DA379_RS09965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DA379_RS09970	COG0295	cytidine deaminase activity
DA379_RS09975	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DA379_RS09985	COG1480	7TM receptor with intracellular HD hydrolase
DA379_RS09990	COG1702	phosphate starvation-inducible protein PhoH
DA379_RS09995	COG0561	phosphatase activity
DA379_RS10010	COG4864	UPF0365 protein
DA379_RS10015	COG1030	water channel activity
DA379_RS10020	COG1610	YqeY-like protein
DA379_RS10030	COG1283	sodium-dependent phosphate transmembrane transporter activity
DA379_RS10035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DA379_RS10040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DA379_RS10070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DA379_RS10085	COG0860	N-Acetylmuramoyl-L-alanine amidase
DA379_RS10100	COG1466	dna polymerase III delta subunit
DA379_RS10110	COG2333	competence protein COMEC
DA379_RS10110	COG0658	competence protein
DA379_RS10115	COG2131	deaminase
DA379_RS10120	COG1596	polysaccharide export
DA379_RS10120	COG1555	photosystem II stabilization
DA379_RS10125	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DA379_RS10130	COG2226	methyltransferase
DA379_RS10135	COG0799	negative regulation of ribosome biogenesis
DA379_RS10140	COG1713	HD superfamily hydrolase involved in NAD metabolism
DA379_RS10150	COG1534	Rna-binding protein
DA379_RS10155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DA379_RS10160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DA379_RS10165	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DA379_RS10175	COG2755	lipolytic protein G-D-S-L family
DA379_RS10185	COG0398	Pfam SNARE associated Golgi protein
DA379_RS10220	COG5444	nuclease activity
DA379_RS10225	COG4282	regulation of fungal-type cell wall biogenesis
DA379_RS10240	COG3708	Transcriptional regulator
DA379_RS10240	COG2207	Transcriptional regulator
DA379_RS10250	COG0563	adenylate kinase activity
DA379_RS10260	COG2814	Major facilitator Superfamily
DA379_RS10270	COG0456	acetyltransferase
DA379_RS10275	COG2318	DinB family
DA379_RS10285	COG0561	phosphatase activity
DA379_RS10290	COG0561	phosphatase activity
DA379_RS10300	COG1482	cell wall glycoprotein biosynthetic process
DA379_RS10305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DA379_RS10305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DA379_RS10305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DA379_RS10310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DA379_RS10310	COG3711	transcriptional antiterminator
DA379_RS10320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DA379_RS10325	COG0583	DNA-binding transcription factor activity
DA379_RS10330	COG2814	Major facilitator Superfamily
DA379_RS10335	COG2124	cytochrome p450
DA379_RS10335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DA379_RS10340	COG1309	transcriptional regulator
DA379_RS10345	COG2226	methyltransferase
DA379_RS10360	COG2116	formate transmembrane transporter activity
DA379_RS10365	COG5609	conserved protein (DUF2294)
DA379_RS10370	COG3383	formate dehydrogenase (NAD+) activity
DA379_RS10375	COG2427	Protein of unknown function (DUF1641)
DA379_RS10385	COG0626	cystathionine gamma-synthase activity
DA379_RS10390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DA379_RS10430	COG0826	peptidase U32
DA379_RS10435	COG0826	peptidase U32
DA379_RS10440	COG4122	O-methyltransferase activity
DA379_RS10445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DA379_RS10460	COG4472	Bacterial protein of unknown function (DUF965)
DA379_RS10470	COG0628	permease
DA379_RS10475	COG1126	abc transporter atp-binding protein
DA379_RS10480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DA379_RS10485	COG0765	amino acid transport
DA379_RS10490	COG0765	amino acid transport
DA379_RS10505	COG3881	PFAM PRC-barrel domain
DA379_RS10510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DA379_RS10515	COG0457	Tetratricopeptide repeat
DA379_RS10525	COG1104	cysteine desulfurase activity
DA379_RS10530	COG1959	2 iron, 2 sulfur cluster binding
DA379_RS10535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DA379_RS10540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DA379_RS10560	COG3103	Sh3 type 3 domain protein
DA379_RS10560	COG4991	sh3 domain protein
DA379_RS10560	COG0860	N-Acetylmuramoyl-L-alanine amidase
DA379_RS10570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DA379_RS10580	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DA379_RS10580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DA379_RS10585	COG5416	Lipopolysaccharide assembly protein A domain
DA379_RS10590	COG0490	domain, Protein
DA379_RS10595	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DA379_RS10595	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DA379_RS10610	COG2323	membrane
DA379_RS10620	COG1862	Preprotein translocase
DA379_RS10665	COG1388	LysM domain
DA379_RS10675	COG0157	Belongs to the NadC ModD family
DA379_RS10680	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DA379_RS10685	COG1104	cysteine desulfurase activity
DA379_RS10690	COG1827	regulation of RNA biosynthetic process
DA379_RS10695	COG0077	Prephenate dehydratase
DA379_RS10710	COG3290	protein histidine kinase activity
DA379_RS10715	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DA379_RS10720	COG2868	ribosomal protein
DA379_RS10730	COG1994	Peptidase M50
DA379_RS10735	COG0739	heme binding
DA379_RS10740	COG2894	cell division
DA379_RS10750	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DA379_RS10760	COG1077	Cell shape determining protein MreB Mrl
DA379_RS10780	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DA379_RS10785	COG0285	dihydrofolate synthase activity
DA379_RS10790	COG0525	valine-tRNA ligase activity
DA379_RS10800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DA379_RS10805	COG1388	LysM domain
DA379_RS10815	COG0113	porphobilinogen synthase activity
DA379_RS10820	COG1587	Uroporphyrinogen-III synthase
DA379_RS10830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DA379_RS10850	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DA379_RS10855	COG1067	ATP-dependent peptidase activity
DA379_RS10855	COG0470	DNA polymerase III
DA379_RS10870	COG0457	Tetratricopeptide repeat
DA379_RS10870	COG1477	protein flavinylation
DA379_RS10885	COG0473	3-isopropylmalate dehydrogenase activity
DA379_RS10900	COG0440	acetolactate synthase activity
DA379_RS10930	COG0622	Phosphoesterase
DA379_RS10935	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DA379_RS10945	COG5401	PFAM Sporulation and spore germination
DA379_RS10955	COG1846	Transcriptional regulator
DA379_RS10960	COG2197	response regulator
DA379_RS10965	COG0824	Thioesterase
DA379_RS10970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DA379_RS10975	COG1053	succinate dehydrogenase
DA379_RS10980	COG2009	succinate dehydrogenase
DA379_RS10985	COG1719	4-vinyl reductase, 4VR
DA379_RS10990	COG0527	aspartate kinase activity
DA379_RS11005	COG3118	belongs to the thioredoxin family
DA379_RS11010	COG3534	alpha-L-arabinofuranosidase
DA379_RS11015	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DA379_RS11020	COG2086	electron transfer activity
DA379_RS11025	COG1024	Enoyl-CoA hydratase
DA379_RS11030	COG1309	transcriptional regulator
DA379_RS11035	COG0318	PFAM AMP-dependent synthetase and ligase
DA379_RS11045	COG3766	membrane
DA379_RS11055	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DA379_RS11055	COG1796	DNA polymerase
DA379_RS11060	COG1286	toxin biosynthetic process
DA379_RS11075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DA379_RS11075	COG0072	phenylalanine-tRNA ligase activity
DA379_RS11080	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DA379_RS11085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DA379_RS11095	COG3835	regulator
DA379_RS11100	COG0277	FAD linked oxidase domain protein
DA379_RS11105	COG0247	lactate metabolic process
DA379_RS11110	COG1966	Carbon starvation protein
DA379_RS11115	COG3534	alpha-L-arabinofuranosidase
DA379_RS11120	COG0395	ABC-type sugar transport system, permease component
DA379_RS11125	COG1175	transmembrane transport
DA379_RS11130	COG1653	transport
DA379_RS11140	COG0647	UMP catabolic process
DA379_RS11145	COG0235	Class ii aldolase
DA379_RS11150	COG1069	ribulokinase activity
DA379_RS11155	COG2160	L-arabinose isomerase activity
DA379_RS11160	COG3507	Belongs to the glycosyl hydrolase 43 family
DA379_RS11165	COG1363	Peptidase, m42
DA379_RS11175	COG3326	Membrane
DA379_RS11180	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DA379_RS11190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DA379_RS11195	COG1346	cytolysis
DA379_RS11200	COG1380	Effector of murein hydrolase LrgA
DA379_RS11205	COG3279	Response regulator of the LytR AlgR family
DA379_RS11210	COG3275	phosphorelay sensor kinase activity
DA379_RS11220	COG1011	Hydrolase
DA379_RS11235	COG0398	Pfam SNARE associated Golgi protein
DA379_RS11240	COG1484	DNA-dependent DNA replication
DA379_RS11245	COG3611	Membrane attachment protein
DA379_RS11260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DA379_RS11265	COG1733	regulation of RNA biosynthetic process
DA379_RS11270	COG2814	Major facilitator Superfamily
DA379_RS11275	COG0656	L-ascorbic acid biosynthetic process
DA379_RS11280	COG0237	dephospho-CoA kinase activity
DA379_RS11285	COG1971	Probably functions as a manganese efflux pump
DA379_RS11290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DA379_RS11295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DA379_RS11295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DA379_RS11300	COG5002	protein histidine kinase activity
DA379_RS11305	COG0745	RESPONSE REGULATOR receiver
DA379_RS11315	COG0538	isocitrate dehydrogenase activity
DA379_RS11320	COG0372	Belongs to the citrate synthase family
DA379_RS11350	COG0628	permease
DA379_RS11355	COG3030	protein affecting phage T7 exclusion by the F plasmid
DA379_RS11360	COG0469	pyruvate kinase activity
DA379_RS11380	COG0281	malic enzyme
DA379_RS11385	COG0587	DNA-directed DNA polymerase activity
DA379_RS11405	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DA379_RS11415	COG4109	DRTGG domain
DA379_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS11440	COG0521	Mo-molybdopterin cofactor biosynthetic process
DA379_RS11450	COG0827	DNA restriction-modification system
DA379_RS11455	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DA379_RS11460	COG3874	Sporulation protein YtfJ
DA379_RS11470	COG1714	RDD family
DA379_RS11475	COG0616	signal peptide processing
DA379_RS11480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DA379_RS11485	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DA379_RS11490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DA379_RS11505	COG1104	cysteine desulfurase activity
DA379_RS11510	COG1114	Component of the transport system for branched-chain amino acids
DA379_RS11520	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DA379_RS11525	COG1309	transcriptional regulator
DA379_RS11530	COG1956	GAF domain-containing protein
DA379_RS11535	COG2203	Gaf domain
DA379_RS11535	COG2199	diguanylate cyclase activity
DA379_RS11550	COG1012	belongs to the aldehyde dehydrogenase family
DA379_RS11555	COG4282	regulation of fungal-type cell wall biogenesis
DA379_RS11565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DA379_RS11565	COG1017	nitric oxide dioxygenase activity
DA379_RS11575	COG0693	protein deglycase activity
DA379_RS11590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DA379_RS11595	COG1378	Sugar-specific transcriptional regulator TrmB
DA379_RS11620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DA379_RS11625	COG0454	-acetyltransferase
DA379_RS11630	COG0517	IMP dehydrogenase activity
DA379_RS11635	COG0123	including yeast histone deacetylase and acetoin utilization protein
DA379_RS11640	COG1360	Flagellar Motor Protein
DA379_RS11645	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DA379_RS11650	COG1609	Transcriptional regulator
DA379_RS11655	COG1605	Chorismate mutase
DA379_RS11655	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DA379_RS11660	COG3118	belongs to the thioredoxin family
DA379_RS11665	COG4980	gas vesicle protein
DA379_RS11670	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DA379_RS11680	COG1674	ftsk spoiiie
DA379_RS11685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DA379_RS11695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA379_RS11705	COG1363	Peptidase, m42
DA379_RS11710	COG5584	Small secreted protein
DA379_RS11715	COG0281	malic enzyme
DA379_RS11720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DA379_RS11735	COG0510	thiamine kinase activity
DA379_RS11740	COG1597	lipid kinase activity
DA379_RS11750	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DA379_RS11755	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DA379_RS11760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DA379_RS11765	COG2252	PERMEase
DA379_RS11770	COG4473	ABC transporter
DA379_RS11775	COG1131	(ABC) transporter
DA379_RS11780	COG1349	DNA-binding transcription factor activity
DA379_RS11785	COG1187	pseudouridine synthase activity
DA379_RS11790	COG2244	polysaccharide biosynthetic process
DA379_RS11795	COG2081	HI0933 family
DA379_RS11800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DA379_RS11815	COG1653	transport
DA379_RS11820	COG1175	transmembrane transport
DA379_RS11825	COG0395	ABC-type sugar transport system, permease component
DA379_RS11830	COG1486	melibiose metabolic process
DA379_RS11840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DA379_RS11855	COG2202	Pas domain
DA379_RS11855	COG1366	Belongs to the anti-sigma-factor antagonist family
DA379_RS11860	COG2814	Major facilitator Superfamily
DA379_RS11865	COG5522	Integral membrane protein (intg_mem_TP0381)
DA379_RS11870	COG0577	efflux transmembrane transporter activity
DA379_RS11875	COG1136	(ABC) transporter
DA379_RS11880	COG2205	protein histidine kinase activity
DA379_RS11885	COG0745	RESPONSE REGULATOR receiver
DA379_RS11890	COG0577	efflux transmembrane transporter activity
DA379_RS11895	COG1136	(ABC) transporter
DA379_RS11915	COG1131	(ABC) transporter
DA379_RS11920	COG1725	Transcriptional regulator
DA379_RS11930	COG1242	4 iron, 4 sulfur cluster binding
DA379_RS11935	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DA379_RS11945	COG0584	glycerophosphoryl diester phosphodiesterase
DA379_RS11955	COG2267	carboxylic ester hydrolase activity
DA379_RS11960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DA379_RS11965	COG1113	amino acid transport
DA379_RS11970	COG0367	asparagine synthase
DA379_RS11990	COG1506	peptidase
DA379_RS11995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DA379_RS12000	COG1116	anion transmembrane transporter activity
DA379_RS12005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DA379_RS12010	COG0494	nUDIX hydrolase
DA379_RS12015	COG4824	toxin secretion phage lysis holin
DA379_RS12020	COG0783	Belongs to the Dps family
DA379_RS12045	COG0288	reversible hydration of carbon dioxide
DA379_RS12055	COG1271	oxidase subunit
DA379_RS12060	COG1294	oxidase, subunit
DA379_RS12075	COG4948	Mandelate Racemase Muconate Lactonizing
DA379_RS12085	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DA379_RS12090	COG0596	Alpha beta hydrolase
DA379_RS12100	COG1169	isochorismate synthase
DA379_RS12105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DA379_RS12110	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DA379_RS12235	COG3859	Proton-coupled thiamine transporter YuaJ
DA379_RS12240	COG2268	Band 7 protein
DA379_RS12245	COG1585	Membrane protein implicated in regulation of membrane protease activity
DA379_RS12250	COG2318	DinB family
DA379_RS12260	COG1454	alcohol dehydrogenase
DA379_RS12265	COG1012	belongs to the aldehyde dehydrogenase family
DA379_RS12270	COG1510	regulation of RNA biosynthetic process
DA379_RS12280	COG0569	domain protein
DA379_RS12285	COG1705	Flagellar rod assembly protein muramidase FlgJ
DA379_RS12290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DA379_RS12290	COG1017	nitric oxide dioxygenase activity
DA379_RS12315	COG0628	permease
DA379_RS12320	COG0673	inositol 2-dehydrogenase activity
DA379_RS12325	COG0693	protein deglycase activity
DA379_RS12330	COG0840	transmembrane signaling receptor activity
DA379_RS12335	COG0840	transmembrane signaling receptor activity
DA379_RS12340	COG0840	transmembrane signaling receptor activity
DA379_RS12345	COG0840	transmembrane signaling receptor activity
DA379_RS12360	COG2070	2-Nitropropane dioxygenase
DA379_RS12365	COG0432	Pfam Uncharacterised protein family UPF0047
DA379_RS12370	COG0366	Alpha amylase catalytic
DA379_RS12375	COG1253	flavin adenine dinucleotide binding
DA379_RS12380	COG2738	Putative neutral zinc metallopeptidase
DA379_RS12395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DA379_RS12425	COG1335	isochorismatase
DA379_RS12435	COG1979	alcohol dehydrogenase
DA379_RS12440	COG1979	alcohol dehydrogenase
DA379_RS12445	COG2155	Conserved Protein
DA379_RS12450	COG1098	S1 RNA binding domain
DA379_RS12455	COG0436	Aminotransferase
DA379_RS12460	COG1522	sequence-specific DNA binding
DA379_RS12465	COG2267	carboxylic ester hydrolase activity
DA379_RS12475	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DA379_RS12480	COG2205	protein histidine kinase activity
DA379_RS12490	COG5018	Exonuclease
DA379_RS12495	COG2814	Major facilitator Superfamily
DA379_RS12500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DA379_RS12505	COG3011	Protein conserved in bacteria
DA379_RS12515	COG3290	protein histidine kinase activity
DA379_RS12520	COG4565	transcriptional regulatory protein
DA379_RS12525	COG1744	ABC transporter substrate-binding protein PnrA-like
DA379_RS12530	COG3845	ABC transporter
DA379_RS12535	COG4603	Belongs to the binding-protein-dependent transport system permease family
DA379_RS12540	COG1079	Belongs to the binding-protein-dependent transport system permease family
DA379_RS12550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DA379_RS12550	COG2111	Na H antiporter
DA379_RS12555	COG2111	Na H antiporter
DA379_RS12560	COG1006	Multisubunit Na H antiporter MnhC subunit
DA379_RS12565	COG0651	ATP synthesis coupled electron transport
DA379_RS12570	COG1863	multisubunit Na H antiporter MnhE subunit
DA379_RS12575	COG2212	antiporter activity
DA379_RS12580	COG1320	monovalent cation:proton antiporter activity
DA379_RS12585	COG2050	protein possibly involved in aromatic compounds catabolism
DA379_RS12590	COG2197	response regulator
DA379_RS12595	COG4585	Histidine kinase
DA379_RS12605	COG0142	geranyltranstransferase activity
DA379_RS12620	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DA379_RS12625	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DA379_RS12630	COG1335	isochorismatase
DA379_RS12635	COG5506	Protein of unknown function (DUF1694)
DA379_RS12650	COG0628	permease
DA379_RS12660	COG1418	mRNA catabolic process
DA379_RS12665	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS12675	COG1511	domain protein
DA379_RS12680	COG1674	ftsk spoiiie
DA379_RS12680	COG0433	COG0433 Predicted ATPase
DA379_RS12685	COG4499	WXG100 protein secretion system (Wss), protein YukC
DA379_RS12690	COG5417	Belongs to the EsaB family
DA379_RS12695	COG4842	Belongs to the WXG100 family
DA379_RS12700	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DA379_RS12700	COG2508	Transcriptional regulator
DA379_RS12705	COG0686	Belongs to the AlaDH PNT family
DA379_RS12710	COG5634	Uncharacterized conserved protein (DUF2278)
DA379_RS12715	COG3251	PFAM MbtH domain protein
DA379_RS12720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS12725	COG1535	isochorismatase
DA379_RS12725	COG3433	isochorismatase activity
DA379_RS12730	COG1021	2,3-dihydroxybenzoate-AMP ligase
DA379_RS12735	COG1169	isochorismate synthase
DA379_RS12740	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS12745	COG2819	hydrolase of the alpha beta superfamily
DA379_RS12750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DA379_RS12755	COG1268	BioY protein
DA379_RS12760	COG2056	Na+-H+ antiporter family
DA379_RS12770	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DA379_RS12775	COG3584	3D domain protein
DA379_RS12790	COG1252	NADH dehydrogenase
DA379_RS12820	COG1131	(ABC) transporter
DA379_RS12845	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
DA379_RS12850	COG0316	Belongs to the HesB IscA family
DA379_RS12860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DA379_RS12870	COG1252	NADH dehydrogenase
DA379_RS12875	COG4837	Protein of unknown function (DUF1462)
DA379_RS12880	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DA379_RS12885	COG1506	peptidase
DA379_RS12885	COG4946	Tricorn protease homolog
DA379_RS12885	COG0823	Involved in the tonB-independent uptake of proteins
DA379_RS12895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DA379_RS12900	COG0460	homoserine dehydrogenase
DA379_RS12905	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DA379_RS12910	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DA379_RS12915	COG0647	UMP catabolic process
DA379_RS12920	COG2445	Protein of unknown function DUF86
DA379_RS12925	COG4470	Protein conserved in bacteria
DA379_RS12940	COG0739	heme binding
DA379_RS12950	COG0737	Belongs to the 5'-nucleotidase family
DA379_RS12955	COG0730	response to heat
DA379_RS12960	COG1801	Protein of unknown function DUF72
DA379_RS12975	COG2508	Transcriptional regulator
DA379_RS12985	COG2814	Major facilitator Superfamily
DA379_RS12990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DA379_RS12995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DA379_RS13000	COG2356	endonuclease I
DA379_RS13005	COG3842	ATPase activity
DA379_RS13010	COG2188	Transcriptional regulator
DA379_RS13015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DA379_RS13020	COG0395	ABC-type sugar transport system, permease component
DA379_RS13025	COG1175	transmembrane transport
DA379_RS13030	COG1653	transport
DA379_RS13035	COG2222	sugar isomerase
DA379_RS13040	COG0789	Transcriptional regulator
DA379_RS13055	COG0322	excinuclease ABC activity
DA379_RS13060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DA379_RS13065	COG2226	methyltransferase
DA379_RS13075	COG3409	Peptidoglycan-binding domain 1 protein
DA379_RS13080	COG0719	Fe-S assembly protein
DA379_RS13085	COG0822	iron-sulfur transferase activity
DA379_RS13090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DA379_RS13095	COG0719	Fe-S assembly protein
DA379_RS13100	COG0396	ATPase activity
DA379_RS13110	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DA379_RS13115	COG1464	Belongs to the NlpA lipoprotein family
DA379_RS13120	COG2011	ABC-type metal ion transport system permease component
DA379_RS13125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DA379_RS13135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA379_RS13140	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DA379_RS13155	COG1393	Belongs to the ArsC family
DA379_RS13160	COG1960	acyl-CoA dehydrogenase activity
DA379_RS13165	COG0183	Belongs to the thiolase family
DA379_RS13170	COG1250	3-hydroxyacyl-CoA dehydrogenase
DA379_RS13170	COG1024	Enoyl-CoA hydratase
DA379_RS13190	COG5577	PFAM Coat F domain
DA379_RS13195	COG1846	Transcriptional regulator
DA379_RS13200	COG0477	Major facilitator Superfamily
DA379_RS13205	COG0583	DNA-binding transcription factor activity
DA379_RS13225	COG1120	ATPase activity
DA379_RS13240	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS13245	COG0783	Belongs to the Dps family
DA379_RS13250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA379_RS13255	COG0745	RESPONSE REGULATOR receiver
DA379_RS13260	COG2205	protein histidine kinase activity
DA379_RS13260	COG2770	Histidine kinase
DA379_RS13270	COG1309	transcriptional regulator
DA379_RS13275	COG0114	fumarate hydratase activity
DA379_RS13285	COG0697	spore germination
DA379_RS13290	COG0814	amino acid
DA379_RS13300	COG2197	response regulator
DA379_RS13305	COG4585	Histidine kinase
DA379_RS13310	COG4758	membrane
DA379_RS13315	COG3595	metallopeptidase activity
DA379_RS13320	COG1842	Phage shock protein A
DA379_RS13325	COG4758	membrane
DA379_RS13330	COG2814	Major facilitator Superfamily
DA379_RS13335	COG2096	Adenosyltransferase
DA379_RS13340	COG1120	ATPase activity
DA379_RS13345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DA379_RS13350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DA379_RS13355	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS13360	COG3386	PFAM SMP-30 Gluconolaconase
DA379_RS13365	COG2205	protein histidine kinase activity
DA379_RS13370	COG0745	RESPONSE REGULATOR receiver
DA379_RS13380	COG1191	sigma factor activity
DA379_RS13390	COG2140	Oxalate decarboxylase
DA379_RS13400	COG1120	ATPase activity
DA379_RS13405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DA379_RS13410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DA379_RS13415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DA379_RS13420	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DA379_RS13425	COG0531	amino acid
DA379_RS13440	COG1988	membrane-bound metal-dependent
DA379_RS13445	COG1368	sulfuric ester hydrolase activity
DA379_RS13450	COG1910	domain protein
DA379_RS13455	COG0725	ABC transporter, periplasmic molybdate-binding protein
DA379_RS13460	COG4149	molybdate abc transporter
DA379_RS13465	COG2197	response regulator
DA379_RS13470	COG3850	Histidine kinase
DA379_RS13475	COG1131	(ABC) transporter
DA379_RS13485	COG0842	Transport permease protein
DA379_RS13490	COG0656	L-ascorbic acid biosynthetic process
DA379_RS13515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DA379_RS13520	COG3973	AAA domain
DA379_RS13525	COG2860	membrane
DA379_RS13535	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DA379_RS13540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DA379_RS13545	COG2217	Heavy metal translocating P-type atpase
DA379_RS13555	COG2608	mercury ion transmembrane transporter activity
DA379_RS13560	COG1937	Protein conserved in bacteria
DA379_RS13565	COG0673	inositol 2-dehydrogenase activity
DA379_RS13575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DA379_RS13580	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DA379_RS13585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DA379_RS13590	COG1126	abc transporter atp-binding protein
DA379_RS13595	COG0765	amino acid transport
DA379_RS13600	COG0765	amino acid transport
DA379_RS13605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DA379_RS13610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DA379_RS13615	COG0454	-acetyltransferase
DA379_RS13620	COG0583	DNA-binding transcription factor activity
DA379_RS13625	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS13630	COG2732	(Barnase) inhibitor
DA379_RS13655	COG0557	exoribonuclease II activity
DA379_RS13660	COG1647	Serine aminopeptidase, S33
DA379_RS13665	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DA379_RS13670	COG1476	TRANSCRIPTIONal
DA379_RS13675	COG1396	sequence-specific DNA binding
DA379_RS13680	COG1396	sequence-specific DNA binding
DA379_RS13685	COG1733	regulation of RNA biosynthetic process
DA379_RS13710	COG1131	(ABC) transporter
DA379_RS13715	COG1174	glycine betaine transport
DA379_RS13720	COG1732	Glycine betaine
DA379_RS13725	COG1174	glycine betaine transport
DA379_RS13730	COG0517	IMP dehydrogenase activity
DA379_RS13730	COG1125	glycine betaine transport
DA379_RS13735	COG1510	regulation of RNA biosynthetic process
DA379_RS13740	COG1174	glycine betaine transport
DA379_RS13745	COG1732	Glycine betaine
DA379_RS13750	COG1174	glycine betaine transport
DA379_RS13755	COG0517	IMP dehydrogenase activity
DA379_RS13755	COG1125	glycine betaine transport
DA379_RS13760	COG1510	regulation of RNA biosynthetic process
DA379_RS13765	COG2095	MarC family integral membrane protein
DA379_RS13770	COG3064	Membrane
DA379_RS13775	COG4640	response to antibiotic
DA379_RS13780	COG0456	acetyltransferase
DA379_RS13795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DA379_RS13810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DA379_RS13815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DA379_RS13820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DA379_RS13830	COG2234	aminopeptidase activity
DA379_RS13850	COG0126	phosphoglycerate kinase activity
DA379_RS13860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DA379_RS13865	COG2390	Transcriptional regulator
DA379_RS13875	COG1609	Transcriptional regulator
DA379_RS13880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DA379_RS13890	COG0583	DNA-binding transcription factor activity
DA379_RS13895	COG0697	spore germination
DA379_RS13900	COG1113	amino acid transport
DA379_RS13905	COG1737	Transcriptional regulator
DA379_RS13910	COG1070	Carbohydrate kinase
DA379_RS13935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DA379_RS13940	COG2186	Transcriptional regulator
DA379_RS13945	COG1620	l-lactate permease
DA379_RS13950	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DA379_RS13960	COG5039	Polysaccharide pyruvyl transferase
DA379_RS13965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DA379_RS13970	COG0110	maltose O-acetyltransferase activity
DA379_RS13975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DA379_RS13980	COG2244	polysaccharide biosynthetic process
DA379_RS13985	COG1216	Glycosyl transferase, family 2
DA379_RS13990	COG5039	Polysaccharide pyruvyl transferase
DA379_RS13995	COG1216	Glycosyl transferase, family 2
DA379_RS14005	COG0438	transferase activity, transferring glycosyl groups
DA379_RS14010	COG1215	transferase activity, transferring glycosyl groups
DA379_RS14015	COG0438	transferase activity, transferring glycosyl groups
DA379_RS14020	COG1086	Polysaccharide biosynthesis protein
DA379_RS14025	COG0489	protein tyrosine kinase activity
DA379_RS14030	COG3944	biosynthesis protein
DA379_RS14035	COG1396	sequence-specific DNA binding
DA379_RS14040	COG2272	Belongs to the type-B carboxylesterase lipase family
DA379_RS14050	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DA379_RS14055	COG2364	Membrane
DA379_RS14060	COG0456	acetyltransferase
DA379_RS14065	COG3479	Phenolic acid decarboxylase
DA379_RS14120	COG2223	nitrite transmembrane transporter activity
DA379_RS14125	COG1609	Transcriptional regulator
DA379_RS14135	COG0583	DNA-binding transcription factor activity
DA379_RS14140	COG2828	Protein conserved in bacteria
DA379_RS14145	COG2814	Major facilitator Superfamily
DA379_RS14145	COG0477	Major facilitator Superfamily
DA379_RS14150	COG1611	Belongs to the LOG family
DA379_RS14155	COG1694	Mazg nucleotide pyrophosphohydrolase
DA379_RS14160	COG0659	secondary active sulfate transmembrane transporter activity
DA379_RS14165	COG0288	reversible hydration of carbon dioxide
DA379_RS14175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DA379_RS14180	COG4290	ribonuclease
DA379_RS14185	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DA379_RS14190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DA379_RS14200	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DA379_RS14210	COG1051	belongs to the nudix hydrolase family
DA379_RS14215	COG0492	ferredoxin-NADP+ reductase activity
DA379_RS14220	COG0791	NLP P60 protein
DA379_RS14220	COG3883	PFAM NLP P60 protein
DA379_RS14225	COG0457	Tetratricopeptide repeat
DA379_RS14230	COG5002	protein histidine kinase activity
DA379_RS14235	COG0745	RESPONSE REGULATOR receiver
DA379_RS14245	COG1132	(ABC) transporter
DA379_RS14250	COG0140	phosphoribosyl-ATP diphosphatase activity
DA379_RS14250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DA379_RS14275	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DA379_RS14290	COG4990	cell redox homeostasis
DA379_RS14295	COG0110	maltose O-acetyltransferase activity
DA379_RS14315	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DA379_RS14325	COG2188	Transcriptional regulator
DA379_RS14330	COG1309	transcriptional regulator
DA379_RS14335	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DA379_RS14340	COG1950	PFAM Membrane protein of
DA379_RS14345	COG1983	PspC domain protein
DA379_RS14350	COG3595	metallopeptidase activity
DA379_RS14365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DA379_RS14375	COG4897	Protein conserved in bacteria
DA379_RS14380	COG0574	Belongs to the PEP-utilizing enzyme family
DA379_RS14380	COG3848	Pyruvate phosphate dikinase
DA379_RS14385	COG1309	transcriptional regulator
DA379_RS14390	COG2814	Major facilitator Superfamily
DA379_RS14420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA379_RS14430	COG3409	Peptidoglycan-binding domain 1 protein
DA379_RS14430	COG0793	Belongs to the peptidase S41A family
DA379_RS14435	COG3420	alginic acid biosynthetic process
DA379_RS14440	COG2177	Part of the ABC transporter FtsEX involved in
DA379_RS14445	COG2884	Cell division ATP-binding protein ftsE
DA379_RS14450	COG2010	Cytochrome c
DA379_RS14470	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DA379_RS14485	COG1516	flagellar protein fliS
DA379_RS14490	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DA379_RS14495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DA379_RS14515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DA379_RS14520	COG1256	bacterial-type flagellum assembly
DA379_RS14520	COG4786	Flagellar basal body rod
DA379_RS14525	COG3418	PFAM FlgN family protein
DA379_RS14530	COG2747	anti-sigma28 factor FlgM
DA379_RS14540	COG1040	competence protein
DA379_RS14550	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DA379_RS14555	COG1307	EDD domain protein, DegV family
DA379_RS14560	COG2197	response regulator
DA379_RS14565	COG4585	Histidine kinase
DA379_RS14570	COG1739	Uncharacterized protein family UPF0029
DA379_RS14575	COG1316	TRANSCRIPTIONal
DA379_RS14580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DA379_RS14585	COG0438	transferase activity, transferring glycosyl groups
DA379_RS14590	COG1215	transferase activity, transferring glycosyl groups
DA379_RS14595	COG3206	protein involved in exopolysaccharide biosynthesis
DA379_RS14600	COG3307	-O-antigen
DA379_RS14605	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DA379_RS14610	COG0438	transferase activity, transferring glycosyl groups
DA379_RS14610	COG0297	glycogen (starch) synthase activity
DA379_RS14615	COG2244	polysaccharide biosynthetic process
DA379_RS14625	COG0860	N-Acetylmuramoyl-L-alanine amidase
DA379_RS14625	COG2247	cell wall binding repeat
DA379_RS14630	COG2247	cell wall binding repeat
DA379_RS14630	COG2385	sporulation resulting in formation of a cellular spore
DA379_RS14640	COG1316	TRANSCRIPTIONal
DA379_RS14645	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DA379_RS14650	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DA379_RS14655	COG1134	teichoic acid transport
DA379_RS14660	COG1682	transport, permease protein
DA379_RS14665	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DA379_RS14675	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DA379_RS14680	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DA379_RS14685	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DA379_RS14690	COG4193	domain, Protein
DA379_RS14695	COG1482	cell wall glycoprotein biosynthetic process
DA379_RS14700	COG0697	spore germination
DA379_RS14705	COG0814	amino acid
DA379_RS14715	COG1215	transferase activity, transferring glycosyl groups
DA379_RS14725	COG1316	TRANSCRIPTIONal
DA379_RS14730	COG0561	phosphatase activity
DA379_RS14735	COG2433	Pfam Transposase IS66
DA379_RS14740	COG0791	NLP P60 protein
DA379_RS14750	COG2843	Capsule synthesis protein
DA379_RS14760	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DA379_RS14770	COG0697	spore germination
DA379_RS14775	COG0814	amino acid
DA379_RS14785	COG1609	Transcriptional regulator
DA379_RS14790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DA379_RS14800	COG1129	ABC transporter
DA379_RS14805	COG1172	Belongs to the binding-protein-dependent transport system permease family
DA379_RS14810	COG1879	ABC-type sugar transport system periplasmic component
DA379_RS14815	COG3103	Sh3 type 3 domain protein
DA379_RS14820	COG2249	NAD(P)H dehydrogenase (quinone) activity
DA379_RS14825	COG3527	Alpha-acetolactate decarboxylase
DA379_RS14830	COG0028	Belongs to the TPP enzyme family
DA379_RS14835	COG0583	DNA-binding transcription factor activity
DA379_RS14840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DA379_RS14855	COG5337	Spore coat protein CotH
DA379_RS14865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DA379_RS14875	COG0405	Gamma-glutamyltransferase
DA379_RS14880	COG1522	sequence-specific DNA binding
DA379_RS14885	COG2059	Chromate
DA379_RS14890	COG2059	Chromate
DA379_RS14900	COG0655	NAD(P)H dehydrogenase (quinone) activity
DA379_RS14905	COG0583	DNA-binding transcription factor activity
DA379_RS14950	COG5444	nuclease activity
DA379_RS14965	COG3878	Protein conserved in bacteria
DA379_RS14970	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DA379_RS14975	COG4464	protein tyrosine phosphatase activity
DA379_RS14980	COG0489	protein tyrosine kinase activity
DA379_RS14985	COG3944	biosynthesis protein
DA379_RS15000	COG4715	Zinc finger, swim domain protein
DA379_RS15005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DA379_RS15010	COG0561	phosphatase activity
DA379_RS15015	COG1349	DNA-binding transcription factor activity
DA379_RS15020	COG0629	single-stranded DNA binding
DA379_RS15045	COG0457	Tetratricopeptide repeat
DA379_RS15050	COG4786	Flagellar basal body rod
DA379_RS15055	COG4786	Flagellar basal body rod
DA379_RS15060	COG1077	Cell shape determining protein MreB Mrl
DA379_RS15065	COG1609	Transcriptional regulator
DA379_RS15070	COG1846	Transcriptional regulator
DA379_RS15075	COG2814	Major facilitator Superfamily
DA379_RS15080	COG1953	Uracil, thiamine, allantoin
DA379_RS15085	COG0477	Major facilitator Superfamily
DA379_RS15090	COG1335	isochorismatase
DA379_RS15095	COG0004	ammonium transporteR
DA379_RS15100	COG0347	Belongs to the P(II) protein family
DA379_RS15105	COG0772	Belongs to the SEDS family
DA379_RS15110	COG0671	phosphoesterase, PA-phosphatase related
DA379_RS15120	COG0739	heme binding
DA379_RS15125	COG1247	-acetyltransferase
DA379_RS15140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DA379_RS15150	COG0726	polysaccharide deacetylase
DA379_RS15160	COG1959	2 iron, 2 sulfur cluster binding
DA379_RS15175	COG0831	urea catabolic process
DA379_RS15180	COG3237	CsbD-like
DA379_RS15185	COG1994	Peptidase M50
DA379_RS15190	COG0457	Tetratricopeptide repeat
DA379_RS15200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DA379_RS15205	COG2304	oxidoreductase activity
DA379_RS15210	COG2304	oxidoreductase activity
DA379_RS15215	COG2385	sporulation resulting in formation of a cellular spore
DA379_RS15220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DA379_RS15230	COG4836	Membrane
DA379_RS15300	COG0698	ribose 5-phosphate isomerase
DA379_RS15305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DA379_RS15315	COG0009	L-threonylcarbamoyladenylate synthase
DA379_RS15320	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DA379_RS15340	COG2890	protein-(glutamine-N5) methyltransferase activity
DA379_RS15345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DA379_RS15350	COG0346	lactoylglutathione lyase activity
DA379_RS15355	COG0789	Transcriptional regulator
DA379_RS15360	COG0679	Auxin Efflux Carrier
DA379_RS15365	COG0281	malic enzyme
DA379_RS15380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DA379_RS15385	COG1494	fructose-1,6-bisphosphatase
DA379_RS15390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DA379_RS15400	COG0191	fructose-bisphosphate aldolase activity
DA379_RS15405	COG2204	response regulator
DA379_RS15410	COG4821	SIS domain
DA379_RS15425	COG0247	lactate metabolic process
DA379_RS15425	COG2181	nitrate reductase activity
DA379_RS15430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DA379_RS15445	COG1132	(ABC) transporter
DA379_RS15450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DA379_RS15460	COG2181	nitrate reductase activity
DA379_RS15465	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DA379_RS15470	COG1140	nitrate reductase beta subunit
DA379_RS15475	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DA379_RS15480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DA379_RS15490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DA379_RS15495	COG2223	nitrite transmembrane transporter activity
DA379_RS15505	COG4506	Protein conserved in bacteria
DA379_RS15510	COG0457	Tetratricopeptide repeat
DA379_RS15555	COG0010	Belongs to the arginase family
DA379_RS15560	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DA379_RS15565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DA379_RS15580	COG1994	Peptidase M50
DA379_RS15585	COG1942	4-Oxalocrotonate Tautomerase
DA379_RS15590	COG1846	Transcriptional regulator
DA379_RS15600	COG0531	amino acid
DA379_RS15605	COG3465	dGTPase activity
DA379_RS15610	COG1078	dGTPase activity
DA379_RS15625	COG1695	Transcriptional regulator
DA379_RS15635	COG1131	(ABC) transporter
DA379_RS15640	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DA379_RS15670	COG0583	DNA-binding transcription factor activity
DA379_RS15675	COG2855	membrane
DA379_RS15680	COG0280	phosphate acetyltransferase
DA379_RS15690	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS15695	COG0436	Aminotransferase
DA379_RS15725	COG2814	Major facilitator Superfamily
DA379_RS15730	COG2814	Major facilitator Superfamily
DA379_RS15735	COG0833	amino acid
DA379_RS15740	COG4187	Peptidase family M20/M25/M40
DA379_RS15745	COG1012	belongs to the aldehyde dehydrogenase family
DA379_RS15750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DA379_RS15760	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DA379_RS15765	COG1091	dTDP-4-dehydrorhamnose reductase activity
DA379_RS15770	COG1088	dTDP-glucose 4,6-dehydratase activity
DA379_RS15775	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DA379_RS15780	COG3980	spore coat polysaccharide biosynthesis protein
DA379_RS15785	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
DA379_RS15790	COG2089	acid synthase
DA379_RS15795	COG0456	acetyltransferase
DA379_RS15800	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DA379_RS15805	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DA379_RS15810	COG0463	Glycosyl transferase, family 2
DA379_RS15820	COG2363	Small membrane protein
DA379_RS15825	COG2233	PERMEase
DA379_RS15840	COG1216	Glycosyl transferase, family 2
DA379_RS15855	COG1695	Transcriptional regulator
DA379_RS15860	COG0351	phosphomethylpyrimidine kinase
DA379_RS15870	COG1621	beta-fructofuranosidase activity
DA379_RS15880	COG3711	transcriptional antiterminator
DA379_RS15890	COG1404	Belongs to the peptidase S8 family
DA379_RS15895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DA379_RS15900	COG0778	Nitroreductase
DA379_RS15905	COG0772	Belongs to the SEDS family
DA379_RS15910	COG0454	-acetyltransferase
DA379_RS15930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DA379_RS15935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DA379_RS15940	COG2261	transglycosylase associated protein
DA379_RS15945	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DA379_RS15950	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DA379_RS15950	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DA379_RS15955	COG2246	polysaccharide biosynthetic process
DA379_RS15960	COG1309	transcriptional regulator
DA379_RS15980	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DA379_RS15985	COG2837	iron assimilation
DA379_RS15990	COG2822	iron ion transport
DA379_RS16010	COG0583	DNA-binding transcription factor activity
DA379_RS16020	COG1346	cytolysis
DA379_RS16025	COG4895	conserved protein (DUF2196)
DA379_RS16030	COG0789	Transcriptional regulator
DA379_RS16035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DA379_RS16040	COG0346	lactoylglutathione lyase activity
DA379_RS16045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DA379_RS16050	COG1404	Belongs to the peptidase S8 family
DA379_RS16055	COG1442	glycosyl transferase family 8
DA379_RS16060	COG2357	RelA SpoT domain protein
DA379_RS16065	COG1575	Belongs to the MenA family. Type 1 subfamily
DA379_RS16085	COG1696	Membrane protein involved in D-alanine export
DA379_RS16095	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DA379_RS16100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DA379_RS16105	COG1486	melibiose metabolic process
DA379_RS16110	COG1447	Phosphotransferase system cellobiose-specific component IIA
DA379_RS16115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DA379_RS16120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DA379_RS16125	COG3711	transcriptional antiterminator
DA379_RS16125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DA379_RS16140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DA379_RS16145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DA379_RS16155	COG0640	Transcriptional regulator
DA379_RS16160	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DA379_RS16165	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DA379_RS16170	COG1447	Phosphotransferase system cellobiose-specific component IIA
DA379_RS16175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DA379_RS16180	COG2723	6-phospho-beta-galactosidase activity
DA379_RS16185	COG1940	carbohydrate kinase activity
DA379_RS16190	COG1482	cell wall glycoprotein biosynthetic process
DA379_RS16200	COG0753	catalase activity
DA379_RS16205	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DA379_RS16210	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DA379_RS16215	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DA379_RS16220	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DA379_RS16225	COG4988	ABC transporter
DA379_RS16230	COG1294	oxidase, subunit
DA379_RS16235	COG1271	oxidase subunit
DA379_RS16240	COG3493	citrate carrier protein
DA379_RS16245	COG0726	polysaccharide deacetylase
DA379_RS16250	COG3842	ATPase activity
DA379_RS16255	COG2508	Transcriptional regulator
DA379_RS16260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DA379_RS16270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DA379_RS16280	COG4894	glucomannan catabolic process
DA379_RS16285	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DA379_RS16290	COG0500	methyltransferase
DA379_RS16295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DA379_RS16310	COG0753	catalase activity
DA379_RS16310	COG0693	protein deglycase activity
DA379_RS16315	COG2851	Citrate transporter
DA379_RS16320	COG2273	Hydrolase Family 16
DA379_RS16330	COG2270	Major facilitator Superfamily
DA379_RS16335	COG0513	Belongs to the DEAD box helicase family
DA379_RS16410	COG0697	spore germination
DA379_RS16415	COG0589	response to stress
DA379_RS16430	COG0494	nUDIX hydrolase
DA379_RS16435	COG3507	Belongs to the glycosyl hydrolase 43 family
DA379_RS16460	COG0010	Belongs to the arginase family
DA379_RS16465	COG0833	amino acid
DA379_RS16470	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DA379_RS16475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DA379_RS16485	COG2390	Transcriptional regulator
DA379_RS16490	COG0561	phosphatase activity
DA379_RS16520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DA379_RS16525	COG5294	Protein conserved in bacteria
DA379_RS16530	COG0577	efflux transmembrane transporter activity
DA379_RS16535	COG1136	(ABC) transporter
DA379_RS16540	COG2205	protein histidine kinase activity
DA379_RS16545	COG0745	RESPONSE REGULATOR receiver
DA379_RS16560	COG1082	Xylose isomerase domain protein TIM barrel
DA379_RS16600	COG1349	DNA-binding transcription factor activity
DA379_RS16605	COG0667	Aldo Keto reductase
DA379_RS16610	COG2814	Major facilitator Superfamily
DA379_RS16620	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS16625	COG2197	response regulator
DA379_RS16630	COG4585	Histidine kinase
DA379_RS16635	COG3239	Fatty acid desaturase
DA379_RS16645	COG1309	transcriptional regulator
DA379_RS16650	COG1012	belongs to the aldehyde dehydrogenase family
DA379_RS16655	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DA379_RS16665	COG0640	Transcriptional regulator
DA379_RS16670	COG2814	Major facilitator Superfamily
DA379_RS16675	COG1714	RDD family
DA379_RS16685	COG0450	alkyl hydroperoxide reductase
DA379_RS16690	COG3634	alkyl hydroperoxide reductase activity
DA379_RS16695	COG1113	amino acid transport
DA379_RS16705	COG2080	2 iron, 2 sulfur cluster binding
DA379_RS16720	COG2068	MobA-Related Protein
DA379_RS16725	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DA379_RS16785	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DA379_RS16790	COG0667	Aldo Keto reductase
DA379_RS16795	COG0456	acetyltransferase
DA379_RS16800	COG0457	Tetratricopeptide repeat
DA379_RS16805	COG0010	Belongs to the arginase family
DA379_RS16810	COG0833	amino acid
DA379_RS16815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DA379_RS16820	COG3829	transcription factor binding
DA379_RS16830	COG0488	(ABC) transporter
DA379_RS16845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DA379_RS16850	COG5002	protein histidine kinase activity
DA379_RS16860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DA379_RS16865	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DA379_RS16870	COG4853	Protein conserved in bacteria
DA379_RS16875	COG4863	YycH protein
DA379_RS16880	COG5002	protein histidine kinase activity
DA379_RS16885	COG0745	RESPONSE REGULATOR receiver
DA379_RS16920	COG0346	lactoylglutathione lyase activity
DA379_RS16925	COG0305	Participates in initiation and elongation during chromosome replication
DA379_RS16940	COG3093	addiction module antidote protein HigA
DA379_RS16950	COG0297	glycogen (starch) synthase activity
DA379_RS16960	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DA379_RS16965	COG0438	transferase activity, transferring glycosyl groups
DA379_RS16985	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DA379_RS16990	COG4241	membrane
DA379_RS17000	COG5577	PFAM Coat F domain
DA379_RS17005	COG1733	regulation of RNA biosynthetic process
DA379_RS17015	COG0697	spore germination
DA379_RS17020	COG1621	beta-fructofuranosidase activity
DA379_RS17025	COG1621	beta-fructofuranosidase activity
DA379_RS17030	COG1802	Transcriptional regulator
DA379_RS17035	COG2318	DinB family
DA379_RS17040	COG2211	Major facilitator Superfamily
DA379_RS17050	COG0778	Nitroreductase
DA379_RS17055	COG1846	Transcriptional regulator
DA379_RS17060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DA379_RS17065	COG1846	Transcriptional regulator
DA379_RS17090	COG0583	DNA-binding transcription factor activity
DA379_RS17095	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS17105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DA379_RS17110	COG0697	spore germination
DA379_RS17115	COG1331	Highly conserved protein containing a thioredoxin domain
DA379_RS17120	COG1090	epimerase
DA379_RS17130	COG1959	2 iron, 2 sulfur cluster binding
DA379_RS17145	COG1331	Highly conserved protein containing a thioredoxin domain
DA379_RS17150	COG1266	CAAX protease self-immunity
DA379_RS17155	COG2814	Major facilitator Superfamily
DA379_RS17155	COG0477	Major facilitator Superfamily
DA379_RS17160	COG0346	lactoylglutathione lyase activity
DA379_RS17165	COG1609	Transcriptional regulator
DA379_RS17170	COG0708	Exodeoxyribonuclease III
DA379_RS17175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DA379_RS17180	COG2169	Transcriptional regulator
DA379_RS17190	COG0629	single-stranded DNA binding
DA379_RS17200	COG0012	GTP binding
DA379_RS17205	COG0243	molybdopterin cofactor binding
DA379_RS17210	COG4481	Protein conserved in bacteria
DA379_RS17215	COG3949	Membrane
DA379_RS17230	COG1475	DNA binding
DA379_RS17235	COG1192	Involved in chromosome partitioning
DA379_RS17260	COG1847	R3H domain protein
DA379_RS17265	COG0706	membrane insertase activity
DA379_RS17285	COG0592	DNA-directed DNA polymerase activity
DA379_RS17290	COG2501	S4 domain
DA379_RS17305	COG0187	DNA topoisomerase II activity
DA379_RS17310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DA379_RS17345	COG0517	IMP dehydrogenase activity
DA379_RS17345	COG0516	GMP reductase activity
DA379_RS17350	COG1686	Belongs to the peptidase S11 family
DA379_RS17370	COG1929	Belongs to the glycerate kinase type-1 family
DA379_RS17380	COG1428	Deoxynucleoside kinase
DA379_RS17385	COG1428	Deoxynucleoside kinase
DA379_RS17390	COG1388	LysM domain
DA379_RS17390	COG3858	chitin binding
DA379_RS17395	COG1335	isochorismatase
DA379_RS17400	COG0590	tRNA wobble adenosine to inosine editing
DA379_RS17410	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DA379_RS17415	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DA379_RS17465	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
DA379_RS17470	COG3853	Toxic anion resistance protein (TelA)
DA379_RS17475	COG1982	Orn Lys Arg decarboxylase major
DA379_RS17485	COG3870	Protein conserved in bacteria
DA379_RS17490	COG1728	Protein conserved in bacteria
DA379_RS17495	COG0470	DNA polymerase III
DA379_RS17500	COG1774	PSP1 C-terminal conserved region
DA379_RS17510	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DA379_RS17520	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DA379_RS17525	COG2002	toxin-antitoxin pair type II binding
DA379_RS17530	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DA379_RS17530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DA379_RS17535	COG0084	hydrolase, TatD family'
DA379_RS17540	COG3584	3D domain protein
DA379_RS17540	COG3583	domain protein
DA379_RS17545	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DA379_RS17550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DA379_RS17560	COG4466	Protein conserved in bacteria
DA379_RS17575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DA379_RS17580	COG0251	oxidation-reduction process
DA379_RS17595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DA379_RS17615	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DA379_RS17620	COG2002	toxin-antitoxin pair type II binding
DA379_RS17625	COG2244	polysaccharide biosynthetic process
DA379_RS17630	COG3956	TIGRFAM MazG family protein
DA379_RS17635	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DA379_RS17650	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DA379_RS17655	COG1098	S1 RNA binding domain
DA379_RS17670	COG2208	phosphoserine phosphatase activity
DA379_RS17675	COG2304	oxidoreductase activity
DA379_RS17680	COG0515	serine threonine protein kinase
DA379_RS17685	COG0037	tRNA processing
DA379_RS17690	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DA379_RS17695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DA379_RS17710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DA379_RS17715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DA379_RS17720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DA379_RS17725	COG0512	Glutamine amidotransferase of anthranilate synthase
DA379_RS17730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DA379_RS17735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DA379_RS17740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DA379_RS17745	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DA379_RS17750	COG1396	sequence-specific DNA binding
DA379_RS17755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DA379_RS17760	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DA379_RS17840	COG4463	regulation of RNA biosynthetic process
DA379_RS17845	COG3880	PFAM UvrB UvrC protein
DA379_RS17860	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DA379_RS17865	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DA379_RS17870	COG4956	integral membrane protein (PIN domain superfamily)
DA379_RS17895	COG1045	serine acetyltransferase
DA379_RS17905	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DA379_RS17910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DA379_RS17915	COG3688	RNA-binding protein containing a PIN domain
DA379_RS17920	COG1595	DNA-templated transcription, initiation
DA379_RS17930	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DA379_RS17935	COG0250	Participates in transcription elongation, termination and antitermination
DA379_RS17960	COG2813	Specifically methylates the guanine in position
DA379_RS17975	COG1358	cellular component organization or biogenesis
DA379_RS18000	COG0596	Alpha beta hydrolase
DA379_RS18110	COG0201	protein transport
DA379_RS18120	COG0024	Methionine aminopeptidase
DA379_RS18135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DA379_RS18160	COG1122	ATPase activity
DA379_RS18165	COG1122	ATPase activity
DA379_RS18170	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DA379_RS18190	COG2226	methyltransferase
DA379_RS18195	COG2318	DinB family
DA379_RS18205	COG0860	N-Acetylmuramoyl-L-alanine amidase
DA379_RS18210	COG0489	protein tyrosine kinase activity
DA379_RS18220	COG2194	sulfuric ester hydrolase activity
DA379_RS18225	COG0726	polysaccharide deacetylase
DA379_RS18285	COG0738	Major facilitator superfamily
DA379_RS18290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DA379_RS18305	COG0659	secondary active sulfate transmembrane transporter activity
DA379_RS18310	COG0385	Bile acid
DA379_RS18315	COG2819	hydrolase of the alpha beta superfamily
DA379_RS18320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DA379_RS18325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DA379_RS18330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DA379_RS18335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DA379_RS18335	COG2207	Transcriptional regulator
DA379_RS18340	COG3876	Protein conserved in bacteria
DA379_RS18345	COG1472	Belongs to the glycosyl hydrolase 3 family
DA379_RS18350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DA379_RS18355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DA379_RS18355	COG1263	PTS System
DA379_RS18365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DA379_RS18370	COG1683	Conserved Protein
DA379_RS18400	COG1595	DNA-templated transcription, initiation
DA379_RS18405	COG5662	AntiSigma factor
DA379_RS18410	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DA379_RS18415	COG4856	YbbR-like protein
DA379_RS18460	COG1346	cytolysis
DA379_RS18465	COG1380	Effector of murein hydrolase LrgA
DA379_RS18470	COG1846	Transcriptional regulator
DA379_RS18475	COG1113	amino acid transport
DA379_RS18480	COG1011	Hydrolase
DA379_RS18490	COG2197	response regulator
DA379_RS18495	COG1131	(ABC) transporter
DA379_RS18540	COG0584	glycerophosphoryl diester phosphodiesterase
DA379_RS18545	COG2271	Major facilitator Superfamily
DA379_RS18560	COG2368	4-hydroxyphenylacetate
DA379_RS18570	COG3409	Peptidoglycan-binding domain 1 protein
DA379_RS18585	COG0371	Dehydrogenase
DA379_RS18595	COG1183	phosphatidylcholine synthase activity
DA379_RS18600	COG0586	Pfam SNARE associated Golgi protein
DA379_RS18605	COG0688	phosphatidylethanolamine metabolic process
DA379_RS18620	COG1301	dicarboxylic acid transport
DA379_RS18625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DA379_RS18630	COG0833	amino acid
DA379_RS18635	COG2040	homocysteine
DA379_RS18640	COG1115	amino acid carrier protein
DA379_RS18645	COG2066	Belongs to the glutaminase family
DA379_RS18650	COG4191	Histidine kinase
DA379_RS18655	COG0784	Response regulator, receiver
DA379_RS18660	COG3173	Aminoglycoside phosphotransferase
DA379_RS18670	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DA379_RS18675	COG0778	Nitroreductase
DA379_RS18680	COG0346	lactoylglutathione lyase activity
DA379_RS18685	COG2259	Doxx family
DA379_RS18690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DA379_RS18710	COG3773	Cell wall hydrolase
DA379_RS18720	COG3540	Alkaline phosphatase
DA379_RS18725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DA379_RS18730	COG0805	protein transport
DA379_RS18740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DA379_RS18745	COG0477	Major facilitator Superfamily
DA379_RS18750	COG1309	transcriptional regulator
DA379_RS18755	COG0252	asparaginase activity
DA379_RS18760	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DA379_RS18765	COG3012	SEC-C Motif Domain Protein
DA379_RS18765	COG1405	negative regulation of cell septum assembly
DA379_RS18770	COG0667	Aldo Keto reductase
DA379_RS18780	COG1595	DNA-templated transcription, initiation
DA379_RS18785	COG1595	DNA-templated transcription, initiation
DA379_RS18790	COG1876	peptidase activity
DA379_RS18795	COG0457	Tetratricopeptide repeat
DA379_RS18800	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS18805	COG0366	Alpha amylase catalytic
DA379_RS18810	COG0803	Belongs to the bacterial solute-binding protein 9 family
DA379_RS18815	COG1121	(ABC) transporter
DA379_RS18820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DA379_RS18825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DA379_RS18830	COG2310	stress, protein
DA379_RS18835	COG2310	stress, protein
DA379_RS18840	COG2310	stress, protein
DA379_RS18845	COG0861	Integral membrane protein TerC family
DA379_RS18855	COG3853	Toxic anion resistance protein (TelA)
DA379_RS18860	COG0477	Major facilitator Superfamily
DA379_RS18865	COG4175	Glycine betaine
DA379_RS18865	COG0517	IMP dehydrogenase activity
DA379_RS18870	COG4176	ABC-type proline glycine betaine transport system permease component
DA379_RS18875	COG2113	Glycine betaine
DA379_RS18880	COG1473	amidohydrolase
DA379_RS18885	COG1288	antiporter activity
DA379_RS18895	COG0366	Alpha amylase catalytic
DA379_RS18905	COG2814	Major facilitator Superfamily
DA379_RS18910	COG1846	Transcriptional regulator
DA379_RS18915	COG1280	lysine exporter protein (LysE YggA)
DA379_RS18920	COG3403	YqcI/YcgG family
DA379_RS18925	COG1113	amino acid transport
DA379_RS18930	COG3665	Urea carboxylase-associated protein
DA379_RS18945	COG1660	Displays ATPase and GTPase activities
DA379_RS18955	COG2271	Major facilitator Superfamily
DA379_RS18960	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DA379_RS18965	COG3458	cephalosporin-C deacetylase activity
DA379_RS18970	COG3541	Predicted nucleotidyltransferase
DA379_RS18975	COG0506	proline dehydrogenase activity
DA379_RS18980	COG1012	belongs to the aldehyde dehydrogenase family
DA379_RS18985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DA379_RS18990	COG2508	Transcriptional regulator
DA379_RS19000	COG1587	Uroporphyrinogen-III synthase
DA379_RS19000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DA379_RS19005	COG2146	nitrite reductase [NAD(P)H] activity
DA379_RS19010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DA379_RS19015	COG0523	cobalamin synthesis protein
DA379_RS19020	COG1063	alcohol dehydrogenase
DA379_RS19025	COG1714	RDD family
DA379_RS19035	COG2723	6-phospho-beta-galactosidase activity
DA379_RS19050	COG3209	COG3209 Rhs family protein
DA379_RS19055	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DA379_RS19060	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DA379_RS19065	COG1733	regulation of RNA biosynthetic process
DA379_RS19070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS19075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS19080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DA379_RS19085	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DA379_RS19100	COG2364	Membrane
DA379_RS19105	COG1126	abc transporter atp-binding protein
DA379_RS19110	COG0765	amino acid transport
DA379_RS19115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DA379_RS19120	COG0583	DNA-binding transcription factor activity
DA379_RS19125	COG0163	prenyltransferase activity
DA379_RS19130	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DA379_RS19145	COG3104	oligopeptide transport
DA379_RS19150	COG5434	Belongs to the glycosyl hydrolase 28 family
DA379_RS19160	COG0697	spore germination
DA379_RS19170	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DA379_RS19175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DA379_RS19180	COG0456	acetyltransferase
DA379_RS19185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DA379_RS19190	COG0765	amino acid transport
DA379_RS19195	COG1126	abc transporter atp-binding protein
DA379_RS19200	COG1473	amidohydrolase
DA379_RS19205	COG2079	MmgE PrpD family protein
DA379_RS19210	COG1136	(ABC) transporter
DA379_RS19215	COG0577	efflux transmembrane transporter activity
DA379_RS19220	COG0745	RESPONSE REGULATOR receiver
DA379_RS19225	COG3850	Histidine kinase
DA379_RS19225	COG5002	protein histidine kinase activity
DA379_RS19230	COG0457	Tetratricopeptide repeat
DA379_RS19245	COG0527	aspartate kinase activity
DA379_RS19255	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DA379_RS19260	COG4605	iron ion homeostasis
DA379_RS19265	COG4604	ABC transporter, ATP-binding protein
DA379_RS19270	COG4607	ABC-type enterochelin transport system periplasmic component
DA379_RS19275	COG2814	Major facilitator Superfamily
DA379_RS19280	COG1309	transcriptional regulator
DA379_RS19285	COG0778	Nitroreductase
DA379_RS19290	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DA379_RS19295	COG0640	Transcriptional regulator
DA379_RS19300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DA379_RS19305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DA379_RS19310	COG1012	belongs to the aldehyde dehydrogenase family
DA379_RS19315	COG4975	Glucose uptake
DA379_RS19320	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS19325	COG4549	nuclear export factor GLE1
DA379_RS19330	COG1276	copper resistance
DA379_RS19330	COG2372	response to copper ion
DA379_RS19335	COG1349	DNA-binding transcription factor activity
DA379_RS19345	COG2213	PTS system mannitol-specific
DA379_RS19350	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DA379_RS19360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DA379_RS19370	COG0561	phosphatase activity
DA379_RS19380	COG1914	H( )-stimulated, divalent metal cation uptake system
DA379_RS19390	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DA379_RS19395	COG1984	allophanate hydrolase subunit 2
DA379_RS19400	COG1414	Transcriptional regulator
DA379_RS19405	COG2755	lipolytic protein G-D-S-L family
DA379_RS19415	COG2329	Antibiotic biosynthesis monooxygenase
DA379_RS19420	COG0768	penicillin binding
DA379_RS19425	COG4989	oxidoreductase activity
DA379_RS19430	COG3711	transcriptional antiterminator
DA379_RS19435	COG0318	PFAM AMP-dependent synthetase and ligase
DA379_RS19440	COG1028	Short-chain dehydrogenase reductase Sdr
DA379_RS19445	COG1917	Cupin 2, conserved barrel domain protein
DA379_RS19450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DA379_RS19455	COG3871	stress protein (general stress protein 26)
DA379_RS19465	COG2814	Major facilitator Superfamily
DA379_RS19470	COG1522	sequence-specific DNA binding
DA379_RS19475	COG0551	DNA topoisomerase type I activity
DA379_RS19475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DA379_RS19480	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DA379_RS19485	COG3706	GGDEF domain
DA379_RS19490	COG5298	Protein conserved in bacteria
DA379_RS19495	COG1215	transferase activity, transferring glycosyl groups