locus-tag	class	description
O9K61_RS00010	COG0592	DNA-directed DNA polymerase activity
O9K61_RS00015	COG2501	S4 domain
O9K61_RS00030	COG0187	DNA topoisomerase II activity
O9K61_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
O9K61_RS00070	COG0516	GMP reductase activity
O9K61_RS00070	COG0517	IMP dehydrogenase activity
O9K61_RS00075	COG1686	Belongs to the peptidase S11 family
O9K61_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
O9K61_RS00105	COG1428	Deoxynucleoside kinase
O9K61_RS00110	COG1428	Deoxynucleoside kinase
O9K61_RS00115	COG1388	LysM domain
O9K61_RS00115	COG3858	chitin binding
O9K61_RS00120	COG1335	isochorismatase
O9K61_RS00125	COG0590	tRNA wobble adenosine to inosine editing
O9K61_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
O9K61_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
O9K61_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
O9K61_RS00195	COG3853	Toxic anion resistance protein (TelA)
O9K61_RS00200	COG1982	Orn Lys Arg decarboxylase major
O9K61_RS00210	COG3870	Protein conserved in bacteria
O9K61_RS00215	COG1728	Protein conserved in bacteria
O9K61_RS00220	COG0470	DNA polymerase III
O9K61_RS00225	COG1774	PSP1 C-terminal conserved region
O9K61_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
O9K61_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
O9K61_RS00250	COG2002	toxin-antitoxin pair type II binding
O9K61_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O9K61_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O9K61_RS00260	COG0084	hydrolase, TatD family'
O9K61_RS00265	COG3583	domain protein
O9K61_RS00265	COG3584	3D domain protein
O9K61_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
O9K61_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
O9K61_RS00285	COG4466	Protein conserved in bacteria
O9K61_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
O9K61_RS00305	COG0251	oxidation-reduction process
O9K61_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
O9K61_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
O9K61_RS00345	COG2002	toxin-antitoxin pair type II binding
O9K61_RS00350	COG2244	polysaccharide biosynthetic process
O9K61_RS00355	COG3956	TIGRFAM MazG family protein
O9K61_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
O9K61_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
O9K61_RS00380	COG1098	S1 RNA binding domain
O9K61_RS00395	COG2208	phosphoserine phosphatase activity
O9K61_RS00400	COG2304	oxidoreductase activity
O9K61_RS00405	COG0515	serine threonine protein kinase
O9K61_RS00410	COG0037	tRNA processing
O9K61_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
O9K61_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
O9K61_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
O9K61_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
O9K61_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
O9K61_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
O9K61_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O9K61_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
O9K61_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
O9K61_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
O9K61_RS00475	COG1396	sequence-specific DNA binding
O9K61_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
O9K61_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
O9K61_RS00565	COG4463	regulation of RNA biosynthetic process
O9K61_RS00570	COG3880	PFAM UvrB UvrC protein
O9K61_RS00580	COG0542	response to heat
O9K61_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
O9K61_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
O9K61_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
O9K61_RS00615	COG1045	serine acetyltransferase
O9K61_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
O9K61_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
O9K61_RS00635	COG3688	RNA-binding protein containing a PIN domain
O9K61_RS00640	COG1595	DNA-templated transcription, initiation
O9K61_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
O9K61_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
O9K61_RS00680	COG2813	Specifically methylates the guanine in position
O9K61_RS00695	COG1358	cellular component organization or biogenesis
O9K61_RS00720	COG0596	Alpha beta hydrolase
O9K61_RS00830	COG0201	protein transport
O9K61_RS00840	COG0024	Methionine aminopeptidase
O9K61_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
O9K61_RS00880	COG1122	ATPase activity
O9K61_RS00885	COG1122	ATPase activity
O9K61_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
O9K61_RS00910	COG2226	methyltransferase
O9K61_RS00915	COG2318	DinB family
O9K61_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
O9K61_RS00930	COG0489	protein tyrosine kinase activity
O9K61_RS00940	COG2194	sulfuric ester hydrolase activity
O9K61_RS00945	COG0726	polysaccharide deacetylase
O9K61_RS01005	COG0738	Major facilitator superfamily
O9K61_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
O9K61_RS01020	COG1063	alcohol dehydrogenase
O9K61_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
O9K61_RS01030	COG0385	Bile acid
O9K61_RS01035	COG2819	hydrolase of the alpha beta superfamily
O9K61_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O9K61_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O9K61_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O9K61_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O9K61_RS01055	COG2207	Transcriptional regulator
O9K61_RS01060	COG3876	Protein conserved in bacteria
O9K61_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
O9K61_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O9K61_RS01075	COG1263	PTS System
O9K61_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O9K61_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O9K61_RS01090	COG1683	Conserved Protein
O9K61_RS01120	COG1595	DNA-templated transcription, initiation
O9K61_RS01125	COG5662	AntiSigma factor
O9K61_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
O9K61_RS01135	COG4856	YbbR-like protein
O9K61_RS01160	COG0515	serine threonine protein kinase
O9K61_RS01170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
O9K61_RS01180	COG1346	cytolysis
O9K61_RS01185	COG1380	Effector of murein hydrolase LrgA
O9K61_RS01190	COG1846	Transcriptional regulator
O9K61_RS01195	COG1113	amino acid transport
O9K61_RS01200	COG1011	Hydrolase
O9K61_RS01205	COG4585	Histidine kinase
O9K61_RS01210	COG2197	response regulator
O9K61_RS01215	COG1131	(ABC) transporter
O9K61_RS01255	COG0531	amino acid
O9K61_RS01260	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
O9K61_RS01275	COG0584	glycerophosphoryl diester phosphodiesterase
O9K61_RS01280	COG2271	Major facilitator Superfamily
O9K61_RS01290	COG2368	4-hydroxyphenylacetate
O9K61_RS01300	COG3409	Peptidoglycan-binding domain 1 protein
O9K61_RS01315	COG0371	Dehydrogenase
O9K61_RS01325	COG1183	phosphatidylcholine synthase activity
O9K61_RS01330	COG0586	Pfam SNARE associated Golgi protein
O9K61_RS01335	COG0688	phosphatidylethanolamine metabolic process
O9K61_RS01350	COG1301	dicarboxylic acid transport
O9K61_RS01355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O9K61_RS01360	COG0833	amino acid
O9K61_RS01365	COG2040	homocysteine
O9K61_RS01370	COG1115	amino acid carrier protein
O9K61_RS01375	COG2066	Belongs to the glutaminase family
O9K61_RS01380	COG4191	Histidine kinase
O9K61_RS01385	COG0784	Response regulator, receiver
O9K61_RS01405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
O9K61_RS01410	COG0778	Nitroreductase
O9K61_RS01415	COG0346	lactoylglutathione lyase activity
O9K61_RS01420	COG2259	Doxx family
O9K61_RS01425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O9K61_RS01435	COG3773	Cell wall hydrolase
O9K61_RS01440	COG3540	Alkaline phosphatase
O9K61_RS01445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
O9K61_RS01450	COG0805	protein transport
O9K61_RS01460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
O9K61_RS01465	COG0477	Major facilitator Superfamily
O9K61_RS01470	COG1309	transcriptional regulator
O9K61_RS01475	COG0252	asparaginase activity
O9K61_RS01480	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
O9K61_RS01485	COG1405	negative regulation of cell septum assembly
O9K61_RS01485	COG3012	SEC-C Motif Domain Protein
O9K61_RS01490	COG0667	Aldo Keto reductase
O9K61_RS01500	COG1595	DNA-templated transcription, initiation
O9K61_RS01505	COG1595	DNA-templated transcription, initiation
O9K61_RS01510	COG1876	peptidase activity
O9K61_RS01515	COG0457	Tetratricopeptide repeat
O9K61_RS01520	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS01525	COG0366	Alpha amylase catalytic
O9K61_RS01530	COG0803	Belongs to the bacterial solute-binding protein 9 family
O9K61_RS01535	COG1121	(ABC) transporter
O9K61_RS01540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
O9K61_RS01545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O9K61_RS01550	COG2310	stress, protein
O9K61_RS01555	COG2310	stress, protein
O9K61_RS01560	COG2310	stress, protein
O9K61_RS01565	COG0861	Integral membrane protein TerC family
O9K61_RS01575	COG3853	Toxic anion resistance protein (TelA)
O9K61_RS01580	COG0477	Major facilitator Superfamily
O9K61_RS01585	COG4175	Glycine betaine
O9K61_RS01585	COG0517	IMP dehydrogenase activity
O9K61_RS01590	COG4176	ABC-type proline glycine betaine transport system permease component
O9K61_RS01595	COG2113	Glycine betaine
O9K61_RS01600	COG1473	amidohydrolase
O9K61_RS01605	COG1288	antiporter activity
O9K61_RS01615	COG0366	Alpha amylase catalytic
O9K61_RS01625	COG2814	Major facilitator Superfamily
O9K61_RS01630	COG1846	Transcriptional regulator
O9K61_RS01635	COG1280	lysine exporter protein (LysE YggA)
O9K61_RS01640	COG3403	YqcI/YcgG family
O9K61_RS01645	COG1113	amino acid transport
O9K61_RS01650	COG3665	Urea carboxylase-associated protein
O9K61_RS01665	COG1082	Xylose isomerase domain protein TIM barrel
O9K61_RS01670	COG2271	Major facilitator Superfamily
O9K61_RS01675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
O9K61_RS01680	COG3458	cephalosporin-C deacetylase activity
O9K61_RS01685	COG3541	Predicted nucleotidyltransferase
O9K61_RS01690	COG0506	proline dehydrogenase activity
O9K61_RS01695	COG1012	belongs to the aldehyde dehydrogenase family
O9K61_RS01700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O9K61_RS01705	COG2508	Transcriptional regulator
O9K61_RS01715	COG1587	Uroporphyrinogen-III synthase
O9K61_RS01715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
O9K61_RS01720	COG2146	nitrite reductase [NAD(P)H] activity
O9K61_RS01725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
O9K61_RS01730	COG0243	molybdopterin cofactor binding
O9K61_RS01735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
O9K61_RS01740	COG2223	nitrite transmembrane transporter activity
O9K61_RS01745	COG0523	cobalamin synthesis protein
O9K61_RS01750	COG1063	alcohol dehydrogenase
O9K61_RS01755	COG1714	RDD family
O9K61_RS01765	COG2723	6-phospho-beta-galactosidase activity
O9K61_RS01775	COG3209	COG3209 Rhs family protein
O9K61_RS01780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
O9K61_RS01785	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
O9K61_RS01790	COG1733	regulation of RNA biosynthetic process
O9K61_RS01795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS01815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS01820	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
O9K61_RS01835	COG0697	spore germination
O9K61_RS01840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O9K61_RS01850	COG2364	Membrane
O9K61_RS01855	COG1126	abc transporter atp-binding protein
O9K61_RS01860	COG0765	amino acid transport
O9K61_RS01865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O9K61_RS01870	COG0583	DNA-binding transcription factor activity
O9K61_RS01875	COG0163	prenyltransferase activity
O9K61_RS01880	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
O9K61_RS01895	COG3104	oligopeptide transport
O9K61_RS01900	COG5434	Belongs to the glycosyl hydrolase 28 family
O9K61_RS01910	COG0697	spore germination
O9K61_RS01920	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
O9K61_RS01925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O9K61_RS01930	COG0456	acetyltransferase
O9K61_RS01935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O9K61_RS01940	COG0765	amino acid transport
O9K61_RS01945	COG1126	abc transporter atp-binding protein
O9K61_RS01950	COG1473	amidohydrolase
O9K61_RS01955	COG2079	MmgE PrpD family protein
O9K61_RS01960	COG1136	(ABC) transporter
O9K61_RS01965	COG0577	efflux transmembrane transporter activity
O9K61_RS01970	COG0745	RESPONSE REGULATOR receiver
O9K61_RS01975	COG5002	protein histidine kinase activity
O9K61_RS01975	COG3850	Histidine kinase
O9K61_RS01980	COG0457	Tetratricopeptide repeat
O9K61_RS01995	COG0527	aspartate kinase activity
O9K61_RS02000	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O9K61_RS02005	COG4605	iron ion homeostasis
O9K61_RS02010	COG4604	ABC transporter, ATP-binding protein
O9K61_RS02015	COG4607	ABC-type enterochelin transport system periplasmic component
O9K61_RS02020	COG2814	Major facilitator Superfamily
O9K61_RS02025	COG1309	transcriptional regulator
O9K61_RS02030	COG0778	Nitroreductase
O9K61_RS02035	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
O9K61_RS02040	COG0640	Transcriptional regulator
O9K61_RS02045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O9K61_RS02050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
O9K61_RS02055	COG1012	belongs to the aldehyde dehydrogenase family
O9K61_RS02060	COG4975	Glucose uptake
O9K61_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS02070	COG4549	nuclear export factor GLE1
O9K61_RS02075	COG2372	response to copper ion
O9K61_RS02075	COG1276	copper resistance
O9K61_RS02080	COG1349	DNA-binding transcription factor activity
O9K61_RS02090	COG2213	PTS system mannitol-specific
O9K61_RS02095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
O9K61_RS02105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
O9K61_RS02115	COG0561	phosphatase activity
O9K61_RS02125	COG1914	H( )-stimulated, divalent metal cation uptake system
O9K61_RS02135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
O9K61_RS02140	COG1984	allophanate hydrolase subunit 2
O9K61_RS02145	COG1414	Transcriptional regulator
O9K61_RS02150	COG2755	lipolytic protein G-D-S-L family
O9K61_RS02160	COG2329	Antibiotic biosynthesis monooxygenase
O9K61_RS02165	COG0768	penicillin binding
O9K61_RS02170	COG4989	oxidoreductase activity
O9K61_RS02175	COG3711	transcriptional antiterminator
O9K61_RS02180	COG0318	PFAM AMP-dependent synthetase and ligase
O9K61_RS02185	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS02190	COG1917	Cupin 2, conserved barrel domain protein
O9K61_RS02195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O9K61_RS02200	COG3871	stress protein (general stress protein 26)
O9K61_RS02210	COG2814	Major facilitator Superfamily
O9K61_RS02215	COG1522	sequence-specific DNA binding
O9K61_RS02220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
O9K61_RS02220	COG0551	DNA topoisomerase type I activity
O9K61_RS02225	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
O9K61_RS02230	COG3706	GGDEF domain
O9K61_RS02235	COG5298	Protein conserved in bacteria
O9K61_RS02240	COG1215	transferase activity, transferring glycosyl groups
O9K61_RS02250	COG0531	amino acid
O9K61_RS02255	COG0494	nUDIX hydrolase
O9K61_RS02260	COG0028	Belongs to the TPP enzyme family
O9K61_RS02285	COG1794	racemase activity, acting on amino acids and derivatives
O9K61_RS02315	COG1914	H( )-stimulated, divalent metal cation uptake system
O9K61_RS02335	COG2076	Multidrug Resistance protein
O9K61_RS02340	COG2217	Heavy metal translocating P-type atpase
O9K61_RS02345	COG3729	General stress protein
O9K61_RS02350	COG0662	Cupin 2, conserved barrel domain protein
O9K61_RS02355	COG2329	Antibiotic biosynthesis monooxygenase
O9K61_RS02360	COG3546	catalase activity
O9K61_RS02365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
O9K61_RS02370	COG3290	protein histidine kinase activity
O9K61_RS02375	COG4565	transcriptional regulatory protein
O9K61_RS02380	COG1301	dicarboxylic acid transport
O9K61_RS02385	COG0628	permease
O9K61_RS02390	COG1131	(ABC) transporter
O9K61_RS02395	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
O9K61_RS02405	COG1960	acyl-CoA dehydrogenase activity
O9K61_RS02420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
O9K61_RS02425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O9K61_RS02435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
O9K61_RS02440	COG0513	Belongs to the DEAD box helicase family
O9K61_RS02445	COG3402	PFAM membrane-flanked domain
O9K61_RS02450	COG3428	Bacterial PH domain
O9K61_RS02455	COG0705	Rhomboid family
O9K61_RS02465	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
O9K61_RS02470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
O9K61_RS02475	COG0864	Transcriptional regulator
O9K61_RS02480	COG2337	Toxic component of a toxin-antitoxin (TA) module
O9K61_RS02485	COG1366	Belongs to the anti-sigma-factor antagonist family
O9K61_RS02490	COG1366	Belongs to the anti-sigma-factor antagonist family
O9K61_RS02495	COG2172	sigma factor antagonist activity
O9K61_RS02500	COG2208	phosphoserine phosphatase activity
O9K61_RS02505	COG1366	Belongs to the anti-sigma-factor antagonist family
O9K61_RS02515	COG1191	sigma factor activity
O9K61_RS02520	COG2208	phosphoserine phosphatase activity
O9K61_RS02525	COG2183	response to ionizing radiation
O9K61_RS02590	COG1959	2 iron, 2 sulfur cluster binding
O9K61_RS02595	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
O9K61_RS02610	COG0457	Tetratricopeptide repeat
O9K61_RS02615	COG2249	NAD(P)H dehydrogenase (quinone) activity
O9K61_RS02630	COG0477	Major facilitator Superfamily
O9K61_RS02635	COG1846	Transcriptional regulator
O9K61_RS02645	COG2030	dehydratase
O9K61_RS02655	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
O9K61_RS02660	COG1959	2 iron, 2 sulfur cluster binding
O9K61_RS02665	COG2910	NAD(P)H-binding
O9K61_RS02670	COG1309	transcriptional regulator
O9K61_RS02675	COG0300	oxidoreductase activity
O9K61_RS02685	COG3239	Fatty acid desaturase
O9K61_RS02690	COG1278	Cold shock
O9K61_RS02695	COG1329	Transcriptional regulator
O9K61_RS02715	COG0456	acetyltransferase
O9K61_RS02715	COG1846	Transcriptional regulator
O9K61_RS02720	COG2271	Major facilitator Superfamily
O9K61_RS02725	COG3621	Patatin-like phospholipase
O9K61_RS02735	COG0662	Cupin 2, conserved barrel domain protein
O9K61_RS02750	COG0277	FAD linked oxidase domain protein
O9K61_RS02775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
O9K61_RS02810	COG0351	phosphomethylpyrimidine kinase
O9K61_RS02825	COG1064	alcohol dehydrogenase
O9K61_RS02830	COG0789	Transcriptional regulator
O9K61_RS02840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O9K61_RS02875	COG2814	Major facilitator Superfamily
O9K61_RS02880	COG1309	transcriptional regulator
O9K61_RS02885	COG0697	spore germination
O9K61_RS02890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O9K61_RS02895	COG5577	PFAM Coat F domain
O9K61_RS02905	COG1063	alcohol dehydrogenase
O9K61_RS02910	COG5577	PFAM Coat F domain
O9K61_RS02920	COG0738	Major facilitator superfamily
O9K61_RS02930	COG0110	maltose O-acetyltransferase activity
O9K61_RS02935	COG4585	Histidine kinase
O9K61_RS02940	COG2197	response regulator
O9K61_RS02945	COG2409	Drug exporters of the RND superfamily
O9K61_RS02950	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
O9K61_RS02955	COG0488	(ABC) transporter
O9K61_RS02960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O9K61_RS02965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O9K61_RS02975	COG2814	Major facilitator Superfamily
O9K61_RS02980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
O9K61_RS02990	COG0730	response to heat
O9K61_RS02995	COG0456	acetyltransferase
O9K61_RS03000	COG0789	Transcriptional regulator
O9K61_RS03000	COG4978	Transcriptional regulator
O9K61_RS03005	COG0697	spore germination
O9K61_RS03010	COG1051	belongs to the nudix hydrolase family
O9K61_RS03015	COG2226	methyltransferase
O9K61_RS03020	COG0473	3-isopropylmalate dehydrogenase activity
O9K61_RS03025	COG1802	Transcriptional regulator
O9K61_RS03030	COG1819	glycosyl
O9K61_RS03045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O9K61_RS03055	COG1388	LysM domain
O9K61_RS03060	COG2814	Major facilitator Superfamily
O9K61_RS03065	COG2188	Transcriptional regulator
O9K61_RS03070	COG2186	Transcriptional regulator
O9K61_RS03075	COG2807	transmembrane transport
O9K61_RS03080	COG2076	Multidrug Resistance protein
O9K61_RS03085	COG2076	Multidrug Resistance protein
O9K61_RS03090	COG1309	transcriptional regulator
O9K61_RS03095	COG0531	amino acid
O9K61_RS03105	COG3832	glyoxalase III activity
O9K61_RS03110	COG0604	alcohol dehydrogenase
O9K61_RS03115	COG2814	Major facilitator Superfamily
O9K61_RS03155	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
O9K61_RS03160	COG0802	atpase or kinase
O9K61_RS03165	COG1214	PFAM Peptidase M22, glycoprotease
O9K61_RS03170	COG0456	acetyltransferase
O9K61_RS03175	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
O9K61_RS03180	COG0488	(ABC) transporter
O9K61_RS03195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
O9K61_RS03200	COG0805	protein transport
O9K61_RS03210	COG1266	CAAX protease self-immunity
O9K61_RS03250	COG0457	Tetratricopeptide repeat
O9K61_RS03255	COG1063	alcohol dehydrogenase
O9K61_RS03260	COG2211	Major facilitator Superfamily
O9K61_RS03265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
O9K61_RS03275	COG1842	Phage shock protein A
O9K61_RS03280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
O9K61_RS03285	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
O9K61_RS03290	COG4260	virion core protein, lumpy skin disease virus
O9K61_RS03295	COG2755	lipolytic protein G-D-S-L family
O9K61_RS03295	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
O9K61_RS03305	COG1595	DNA-templated transcription, initiation
O9K61_RS03310	COG1063	alcohol dehydrogenase
O9K61_RS03315	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
O9K61_RS03320	COG0823	Involved in the tonB-independent uptake of proteins
O9K61_RS03335	COG2132	Multicopper oxidase
O9K61_RS03340	COG1113	amino acid transport
O9K61_RS03345	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
O9K61_RS03350	COG0714	Associated with various cellular activities
O9K61_RS03355	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
O9K61_RS03360	COG1305	Transglutaminase-like
O9K61_RS03385	COG2252	PERMEase
O9K61_RS03390	COG3064	Membrane
O9K61_RS03410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
O9K61_RS03415	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
O9K61_RS03420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
O9K61_RS03425	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
O9K61_RS03430	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
O9K61_RS03445	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
O9K61_RS03455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
O9K61_RS03460	COG0138	bifunctional purine biosynthesis protein purh
O9K61_RS03465	COG0151	Belongs to the GarS family
O9K61_RS03480	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
O9K61_RS03485	COG1470	cell adhesion involved in biofilm formation
O9K61_RS03490	COG4496	protein, YerC YecD
O9K61_RS03495	COG0069	glutamate synthase activity
O9K61_RS03505	COG0210	DNA helicase
O9K61_RS03515	COG4851	CamS sex pheromone cAM373 precursor
O9K61_RS03520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
O9K61_RS03525	COG1285	pathogenesis
O9K61_RS03530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O9K61_RS03550	COG1309	transcriptional regulator
O9K61_RS03555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
O9K61_RS03560	COG1597	lipid kinase activity
O9K61_RS03565	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
O9K61_RS03570	COG1106	Psort location Cytoplasmic, score
O9K61_RS03605	COG5444	nuclease activity
O9K61_RS03635	COG3546	catalase activity
O9K61_RS03640	COG0454	-acetyltransferase
O9K61_RS03650	COG2323	membrane
O9K61_RS03655	COG2329	Antibiotic biosynthesis monooxygenase
O9K61_RS03660	COG0346	lactoylglutathione lyase activity
O9K61_RS03665	COG1366	Belongs to the anti-sigma-factor antagonist family
O9K61_RS03670	COG5583	Uncharacterized small protein (DUF2292)
O9K61_RS03675	COG0196	riboflavin kinase activity
O9K61_RS03680	COG0670	Belongs to the BI1 family
O9K61_RS03685	COG1846	Transcriptional regulator
O9K61_RS03690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
O9K61_RS03700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
O9K61_RS03700	COG2124	cytochrome p450
O9K61_RS03715	COG1131	(ABC) transporter
O9K61_RS03760	COG4106	trans-aconitate 2-methyltransferase activity
O9K61_RS03765	COG1368	sulfuric ester hydrolase activity
O9K61_RS03770	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
O9K61_RS03775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O9K61_RS03780	COG1442	glycosyl transferase family 8
O9K61_RS03785	COG1216	Glycosyl transferase, family 2
O9K61_RS03790	COG1442	glycosyl transferase family 8
O9K61_RS03795	COG2223	nitrite transmembrane transporter activity
O9K61_RS03800	COG0531	amino acid
O9K61_RS03805	COG1012	belongs to the aldehyde dehydrogenase family
O9K61_RS03810	COG0840	transmembrane signaling receptor activity
O9K61_RS03815	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS03820	COG0463	Glycosyl transferase, family 2
O9K61_RS03820	COG0457	Tetratricopeptide repeat
O9K61_RS03825	COG0488	(ABC) transporter
O9K61_RS03830	COG0789	Transcriptional regulator
O9K61_RS03835	COG2814	Major facilitator Superfamily
O9K61_RS03840	COG0488	(ABC) transporter
O9K61_RS03845	COG0513	Belongs to the DEAD box helicase family
O9K61_RS03850	COG0456	acetyltransferase
O9K61_RS03855	COG2130	NADP-dependent
O9K61_RS03870	COG3866	Pectate lyase
O9K61_RS03875	COG0471	metal ion transport
O9K61_RS03910	COG3290	protein histidine kinase activity
O9K61_RS03915	COG4565	transcriptional regulatory protein
O9K61_RS03920	COG3181	Tripartite tricarboxylate transporter family receptor
O9K61_RS03925	COG2851	Citrate transporter
O9K61_RS03930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O9K61_RS03935	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
O9K61_RS03945	COG2258	MOSC domain
O9K61_RS03965	COG0024	Methionine aminopeptidase
O9K61_RS03970	COG1263	PTS System
O9K61_RS03970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O9K61_RS03980	COG1368	sulfuric ester hydrolase activity
O9K61_RS03990	COG0071	Belongs to the small heat shock protein (HSP20) family
O9K61_RS04005	COG1263	PTS System
O9K61_RS04005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O9K61_RS04010	COG0366	Alpha amylase catalytic
O9K61_RS04015	COG2188	Transcriptional regulator
O9K61_RS04020	COG0778	Nitroreductase
O9K61_RS04035	COG0737	Belongs to the 5'-nucleotidase family
O9K61_RS04040	COG0693	protein deglycase activity
O9K61_RS04045	COG1609	Transcriptional regulator
O9K61_RS04060	COG2814	Major facilitator Superfamily
O9K61_RS04070	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
O9K61_RS04075	COG4980	gas vesicle protein
O9K61_RS04080	COG1295	ribonuclease BN
O9K61_RS04090	COG0477	Major facilitator Superfamily
O9K61_RS04095	COG0387	Pfam Sodium calcium exchanger
O9K61_RS04105	COG0668	transmembrane transport
O9K61_RS04110	COG0535	radical SAM domain protein
O9K61_RS04120	COG0726	polysaccharide deacetylase
O9K61_RS04125	COG2084	Dehydrogenase
O9K61_RS04135	COG0598	Magnesium transport protein CorA
O9K61_RS04140	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
O9K61_RS04145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
O9K61_RS04155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
O9K61_RS04160	COG4637	Psort location Cytoplasmic, score
O9K61_RS04165	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
O9K61_RS04170	COG0022	dehydrogenase e1 component
O9K61_RS04175	COG0508	dehydrogenase complex catalyzes the overall conversion of
O9K61_RS04180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
O9K61_RS04185	COG3284	Transcriptional regulator
O9K61_RS04195	COG1486	melibiose metabolic process
O9K61_RS04200	COG1737	Transcriptional regulator
O9K61_RS04205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O9K61_RS04205	COG1263	PTS System
O9K61_RS04210	COG1132	(ABC) transporter
O9K61_RS04215	COG1132	(ABC) transporter
O9K61_RS04220	COG2259	Doxx family
O9K61_RS04225	COG2514	catechol 2,3-dioxygenase activity
O9K61_RS04235	COG1695	Transcriptional regulator
O9K61_RS04240	COG2249	NAD(P)H dehydrogenase (quinone) activity
O9K61_RS04245	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
O9K61_RS04250	COG0574	Belongs to the PEP-utilizing enzyme family
O9K61_RS04250	COG3848	Pyruvate phosphate dikinase
O9K61_RS04255	COG2732	(Barnase) inhibitor
O9K61_RS04260	COG2318	DinB family
O9K61_RS04265	COG2814	Major facilitator Superfamily
O9K61_RS04270	COG1846	Transcriptional regulator
O9K61_RS04275	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
O9K61_RS04275	COG0392	lysyltransferase activity
O9K61_RS04280	COG0384	phenazine biosynthesis protein PhzF
O9K61_RS04285	COG0778	Nitroreductase
O9K61_RS04300	COG1090	epimerase
O9K61_RS04315	COG2814	Major facilitator Superfamily
O9K61_RS04325	COG3591	Belongs to the peptidase S1B family
O9K61_RS04340	COG3103	Sh3 type 3 domain protein
O9K61_RS04345	COG5658	integral membrane protein
O9K61_RS04350	COG0596	Alpha beta hydrolase
O9K61_RS04355	COG0463	Glycosyl transferase, family 2
O9K61_RS04360	COG4485	Bacterial membrane protein, YfhO
O9K61_RS04365	COG1988	membrane-bound metal-dependent
O9K61_RS04370	COG0582	viral genome integration into host DNA
O9K61_RS04410	COG3645	SOS response
O9K61_RS04410	COG3646	Phage regulatory protein
O9K61_RS04435	COG0305	Participates in initiation and elongation during chromosome replication
O9K61_RS04460	COG1595	DNA-templated transcription, initiation
O9K61_RS04510	COG0740	serine-type endopeptidase activity
O9K61_RS04555	COG5280	Phage tail tape measure protein TP901
O9K61_RS04555	COG3953	SLT domain
O9K61_RS04620	COG0457	Tetratricopeptide repeat
O9K61_RS04630	COG1194	a g-specific adenine glycosylase
O9K61_RS04640	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS04660	COG1132	(ABC) transporter
O9K61_RS04665	COG4129	membrane
O9K61_RS04675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
O9K61_RS04680	COG0735	belongs to the Fur family
O9K61_RS04790	COG1757	Na H antiporter
O9K61_RS04795	COG3340	Belongs to the peptidase S51 family
O9K61_RS04805	COG0277	FAD linked oxidase domain protein
O9K61_RS04815	COG0747	negative chemotaxis
O9K61_RS04820	COG0601	transmembrane transport
O9K61_RS04825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O9K61_RS04830	COG0444	Belongs to the ABC transporter superfamily
O9K61_RS04835	COG4608	Belongs to the ABC transporter superfamily
O9K61_RS04840	COG0753	catalase activity
O9K61_RS04850	COG1116	anion transmembrane transporter activity
O9K61_RS04855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
O9K61_RS04860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
O9K61_RS04880	COG1476	TRANSCRIPTIONal
O9K61_RS04890	COG3382	B3 4 domain protein
O9K61_RS04895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
O9K61_RS04905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
O9K61_RS04910	COG0789	Transcriptional regulator
O9K61_RS04915	COG1664	Polymer-forming cytoskeletal
O9K61_RS04920	COG1664	Polymer-forming cytoskeletal
O9K61_RS04925	COG2766	serine protein kinase
O9K61_RS04935	COG1846	Transcriptional regulator
O9K61_RS04940	COG1566	PFAM secretion protein HlyD family protein
O9K61_RS04945	COG2814	Major facilitator Superfamily
O9K61_RS04950	COG0655	NAD(P)H dehydrogenase (quinone) activity
O9K61_RS04965	COG1725	Transcriptional regulator
O9K61_RS04970	COG1131	(ABC) transporter
O9K61_RS04975	COG1131	(ABC) transporter
O9K61_RS04980	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
O9K61_RS04985	COG1278	Cold shock
O9K61_RS04990	COG1464	Belongs to the NlpA lipoprotein family
O9K61_RS04995	COG3706	GGDEF domain
O9K61_RS05000	COG1823	symporter activity
O9K61_RS05020	COG5577	PFAM Coat F domain
O9K61_RS05025	COG0737	Belongs to the 5'-nucleotidase family
O9K61_RS05025	COG1525	nuclease
O9K61_RS05025	COG4085	toxin activity
O9K61_RS05030	COG3764	Sortase (surface protein transpeptidase)
O9K61_RS05035	COG0564	pseudouridine synthase activity
O9K61_RS05045	COG0517	IMP dehydrogenase activity
O9K61_RS05050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
O9K61_RS05055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
O9K61_RS05055	COG3153	acetyltransferase
O9K61_RS05065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
O9K61_RS05070	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
O9K61_RS05075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
O9K61_RS05085	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
O9K61_RS05090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
O9K61_RS05095	COG4585	Histidine kinase
O9K61_RS05095	COG2203	Gaf domain
O9K61_RS05100	COG2197	response regulator
O9K61_RS05105	COG0431	NADPH-dependent FMN reductase
O9K61_RS05120	COG0791	NLP P60 protein
O9K61_RS05120	COG1388	LysM domain
O9K61_RS05125	COG1959	2 iron, 2 sulfur cluster binding
O9K61_RS05135	COG2719	SpoVR family
O9K61_RS05140	COG1785	Belongs to the alkaline phosphatase family
O9K61_RS05145	COG0791	NLP P60 protein
O9K61_RS05145	COG1388	LysM domain
O9K61_RS05150	COG0583	DNA-binding transcription factor activity
O9K61_RS05155	COG0372	Belongs to the citrate synthase family
O9K61_RS05160	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS05165	COG0531	amino acid
O9K61_RS05170	COG0733	neurotransmitter:sodium symporter activity
O9K61_RS05185	COG1595	DNA-templated transcription, initiation
O9K61_RS05190	COG0204	Acyl-transferase
O9K61_RS05195	COG1253	flavin adenine dinucleotide binding
O9K61_RS05200	COG0789	Transcriptional regulator
O9K61_RS05205	COG0436	Aminotransferase
O9K61_RS05210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
O9K61_RS05215	COG1253	flavin adenine dinucleotide binding
O9K61_RS05220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
O9K61_RS05225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
O9K61_RS05230	COG0584	glycerophosphoryl diester phosphodiesterase
O9K61_RS05240	COG0668	transmembrane transport
O9K61_RS05245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
O9K61_RS05250	COG0726	polysaccharide deacetylase
O9K61_RS05255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O9K61_RS05260	COG3226	Transcriptional regulator
O9K61_RS05270	COG0589	response to stress
O9K61_RS05275	COG1132	(ABC) transporter
O9K61_RS05280	COG1132	(ABC) transporter
O9K61_RS05285	COG0702	epimerase
O9K61_RS05305	COG0189	ligase activity
O9K61_RS05310	COG0189	ligase activity
O9K61_RS05325	COG4335	DNA alkylation repair
O9K61_RS05330	COG0561	phosphatase activity
O9K61_RS05335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
O9K61_RS05345	COG0475	glutathione-regulated potassium exporter activity
O9K61_RS05350	COG0490	domain, Protein
O9K61_RS05360	COG1024	Enoyl-CoA hydratase
O9K61_RS05370	COG4152	abc transporter atp-binding protein
O9K61_RS05375	COG1668	transmembrane transport
O9K61_RS05380	COG0420	3'-5' exonuclease activity
O9K61_RS05385	COG4717	serine-type aminopeptidase activity
O9K61_RS05400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
O9K61_RS05435	COG4980	gas vesicle protein
O9K61_RS05450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
O9K61_RS05455	COG0537	adenosine 5'-monophosphoramidase activity
O9K61_RS05460	COG1131	(ABC) transporter
O9K61_RS05465	COG4473	ABC transporter
O9K61_RS05475	COG1473	amidohydrolase
O9K61_RS05480	COG3069	C4-dicarboxylate transmembrane transporter activity
O9K61_RS05485	COG2329	Antibiotic biosynthesis monooxygenase
O9K61_RS05490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O9K61_RS05500	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
O9K61_RS05505	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
O9K61_RS05510	COG1309	transcriptional regulator
O9K61_RS05515	COG1511	domain protein
O9K61_RS05520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
O9K61_RS05530	COG1363	Peptidase, m42
O9K61_RS05535	COG1301	dicarboxylic acid transport
O9K61_RS05545	COG1234	tRNA 3'-trailer cleavage
O9K61_RS05550	COG0095	Lipoate-protein ligase
O9K61_RS05555	COG0702	epimerase
O9K61_RS05560	COG0318	PFAM AMP-dependent synthetase and ligase
O9K61_RS05570	COG0501	Belongs to the peptidase M48B family
O9K61_RS05575	COG1404	Belongs to the peptidase S8 family
O9K61_RS05580	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
O9K61_RS05585	COG0406	alpha-ribazole phosphatase activity
O9K61_RS05590	COG0183	Belongs to the thiolase family
O9K61_RS05595	COG0318	PFAM AMP-dependent synthetase and ligase
O9K61_RS05600	COG1268	BioY protein
O9K61_RS05605	COG0840	transmembrane signaling receptor activity
O9K61_RS05610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
O9K61_RS05610	COG0723	plastoquinol--plastocyanin reductase activity
O9K61_RS05615	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS05625	COG4903	ComK protein
O9K61_RS05635	COG5646	InterPro IPR014922
O9K61_RS05660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O9K61_RS05675	COG0398	Pfam SNARE associated Golgi protein
O9K61_RS05680	COG0681	Belongs to the peptidase S26 family
O9K61_RS05685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
O9K61_RS05690	COG1846	Transcriptional regulator
O9K61_RS05695	COG3180	Ammonia monooxygenase
O9K61_RS05700	COG2814	Major facilitator Superfamily
O9K61_RS05710	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
O9K61_RS05730	COG0420	3'-5' exonuclease activity
O9K61_RS05735	COG0419	ATPase involved in DNA repair
O9K61_RS05740	COG1403	HNH endonuclease
O9K61_RS05780	COG0179	Fumarylacetoacetate (FAA) hydrolase
O9K61_RS05795	COG0367	asparagine synthase
O9K61_RS05800	COG1562	ergosterol biosynthetic process
O9K61_RS05805	COG0534	Mate efflux family protein
O9K61_RS05810	COG1917	Cupin 2, conserved barrel domain protein
O9K61_RS05810	COG2207	Transcriptional regulator
O9K61_RS05815	COG2318	DinB family
O9K61_RS05820	COG1357	PFAM Pentapeptide repeats (8 copies)
O9K61_RS05825	COG2153	protein acetylation
O9K61_RS05830	COG0646	methionine synthase
O9K61_RS05830	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
O9K61_RS05840	COG2996	Protein conserved in bacteria
O9K61_RS05845	COG1744	ABC transporter substrate-binding protein PnrA-like
O9K61_RS05850	COG0840	transmembrane signaling receptor activity
O9K61_RS05855	COG2124	cytochrome p450
O9K61_RS05865	COG1307	EDD domain protein, DegV family
O9K61_RS05870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O9K61_RS05890	COG0561	phosphatase activity
O9K61_RS05895	COG1073	alpha beta
O9K61_RS05900	COG2151	metal-sulfur cluster biosynthetic enzyme
O9K61_RS05910	COG0277	FAD linked oxidase domain protein
O9K61_RS05915	COG2271	Major facilitator Superfamily
O9K61_RS05925	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
O9K61_RS05935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
O9K61_RS05940	COG0505	Belongs to the CarA family
O9K61_RS05945	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
O9K61_RS05950	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
O9K61_RS05965	COG2267	carboxylic ester hydrolase activity
O9K61_RS05975	COG1744	ABC transporter substrate-binding protein PnrA-like
O9K61_RS05990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
O9K61_RS05995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
O9K61_RS06000	COG5504	Zn-dependent protease
O9K61_RS06005	COG0444	Belongs to the ABC transporter superfamily
O9K61_RS06010	COG4608	Belongs to the ABC transporter superfamily
O9K61_RS06020	COG0601	transmembrane transport
O9K61_RS06025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O9K61_RS06035	COG0180	Tryptophanyl-tRNA synthetase
O9K61_RS06040	COG4166	transmembrane transport
O9K61_RS06045	COG0601	transmembrane transport
O9K61_RS06050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O9K61_RS06055	COG0444	Belongs to the ABC transporter superfamily
O9K61_RS06060	COG4608	Belongs to the ABC transporter superfamily
O9K61_RS06070	COG0456	acetyltransferase
O9K61_RS06075	COG1393	Belongs to the ArsC family
O9K61_RS06080	COG0861	Integral membrane protein TerC family
O9K61_RS06085	COG4862	establishment of competence for transformation
O9K61_RS06090	COG4469	Competence protein
O9K61_RS06095	COG1164	Oligoendopeptidase f
O9K61_RS06105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
O9K61_RS06110	COG2346	COG2346, Truncated hemoglobins
O9K61_RS06115	COG0741	lytic transglycosylase activity
O9K61_RS06120	COG4116	CYTH
O9K61_RS06130	COG2357	RelA SpoT domain protein
O9K61_RS06135	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
O9K61_RS06140	COG0564	pseudouridine synthase activity
O9K61_RS06150	COG0569	domain protein
O9K61_RS06150	COG0475	glutathione-regulated potassium exporter activity
O9K61_RS06155	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
O9K61_RS06160	COG0352	thiamine-phosphate diphosphorylase activity
O9K61_RS06165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
O9K61_RS06170	COG2104	thiamine diphosphate biosynthetic process
O9K61_RS06180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
O9K61_RS06185	COG0351	phosphomethylpyrimidine kinase
O9K61_RS06190	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
O9K61_RS06245	COG0210	DNA helicase
O9K61_RS06265	COG1131	(ABC) transporter
O9K61_RS06275	COG2153	protein acetylation
O9K61_RS06285	COG2382	esterase
O9K61_RS06290	COG0626	cystathionine gamma-synthase activity
O9K61_RS06295	COG0626	cystathionine gamma-synthase activity
O9K61_RS06335	COG5444	nuclease activity
O9K61_RS06355	COG2367	Beta-lactamase
O9K61_RS06360	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
O9K61_RS06365	COG2814	Major facilitator Superfamily
O9K61_RS06370	COG1846	Transcriptional regulator
O9K61_RS06380	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
O9K61_RS06385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
O9K61_RS06390	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
O9K61_RS06395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O9K61_RS06395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O9K61_RS06400	COG1447	Phosphotransferase system cellobiose-specific component IIA
O9K61_RS06430	COG1285	pathogenesis
O9K61_RS06445	COG2205	protein histidine kinase activity
O9K61_RS06455	COG3383	formate dehydrogenase (NAD+) activity
O9K61_RS06460	COG2427	Protein of unknown function (DUF1641)
O9K61_RS06465	COG2124	cytochrome p450
O9K61_RS06470	COG1819	glycosyl
O9K61_RS06480	COG1587	Uroporphyrinogen-III synthase
O9K61_RS06485	COG0390	transport system, permease component
O9K61_RS06490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
O9K61_RS06495	COG0697	spore germination
O9K61_RS06500	COG4297	protein containing double-stranded beta helix domain
O9K61_RS06510	COG1252	NADH dehydrogenase
O9K61_RS06520	COG2211	Major facilitator Superfamily
O9K61_RS06525	COG1609	Transcriptional regulator
O9K61_RS06530	COG0246	Mannitol dehydrogenase
O9K61_RS06535	COG2721	sulfolactate sulfo-lyase activity
O9K61_RS06540	COG0730	response to heat
O9K61_RS06545	COG2318	DinB family
O9K61_RS06550	COG0457	Tetratricopeptide repeat
O9K61_RS06560	COG1388	LysM domain
O9K61_RS06560	COG3409	Peptidoglycan-binding domain 1 protein
O9K61_RS06560	COG5632	N-Acetylmuramoyl-L-alanine amidase
O9K61_RS06570	COG4195	phage-related replication protein
O9K61_RS06580	COG2856	Zn peptidase
O9K61_RS06585	COG1396	sequence-specific DNA binding
O9K61_RS06595	COG1522	sequence-specific DNA binding
O9K61_RS06600	COG1484	DNA-dependent DNA replication
O9K61_RS06620	COG1595	DNA-templated transcription, initiation
O9K61_RS06625	COG3728	DNA packaging
O9K61_RS06625	COG5484	DNA packaging
O9K61_RS06630	COG1783	phage Terminase large subunit
O9K61_RS06635	COG5518	Phage portal protein
O9K61_RS06640	COG0338	D12 class N6 adenine-specific DNA methyltransferase
O9K61_RS06645	COG4653	Phage capsid family
O9K61_RS06695	COG5412	phage tail tape measure protein
O9K61_RS06695	COG3953	SLT domain
O9K61_RS06695	COG3953	SLT domain
O9K61_RS06695	COG3953	SLT domain
O9K61_RS06695	COG5412	phage tail tape measure protein
O9K61_RS06695	COG5412	phage tail tape measure protein
O9K61_RS06700	COG1652	LysM domain
O9K61_RS06705	COG4193	domain, Protein
O9K61_RS06715	COG3628	GPW Gp25 family protein
O9K61_RS06720	COG3299	homolog of phage Mu protein gp47
O9K61_RS06725	COG3778	Protein conserved in bacteria
O9K61_RS06765	COG3409	Peptidoglycan-binding domain 1 protein
O9K61_RS06765	COG5632	N-Acetylmuramoyl-L-alanine amidase
O9K61_RS06780	COG0306	phosphate transporter
O9K61_RS06785	COG1392	Phosphate transport regulator
O9K61_RS06790	COG0531	amino acid
O9K61_RS06795	COG0346	lactoylglutathione lyase activity
O9K61_RS06800	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
O9K61_RS06805	COG0463	Glycosyl transferase, family 2
O9K61_RS06815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O9K61_RS06820	COG0477	Major facilitator Superfamily
O9K61_RS06825	COG2362	D-Aminopeptidase
O9K61_RS06830	COG0601	transmembrane transport
O9K61_RS06835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
O9K61_RS06840	COG0444	Belongs to the ABC transporter superfamily
O9K61_RS06845	COG4166	transmembrane transport
O9K61_RS06850	COG1619	proteins homologs of microcin C7 resistance protein MccF
O9K61_RS06855	COG4948	Mandelate Racemase Muconate Lactonizing
O9K61_RS06860	COG0791	NLP P60 protein
O9K61_RS06865	COG4608	Belongs to the ABC transporter superfamily
O9K61_RS06870	COG2706	6-phosphogluconolactonase activity
O9K61_RS06875	COG1834	amidinotransferase
O9K61_RS06880	COG1607	acyl-coa hydrolase
O9K61_RS06885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O9K61_RS06890	COG2076	Multidrug Resistance protein
O9K61_RS06895	COG2076	Multidrug Resistance protein
O9K61_RS06900	COG0788	formyltetrahydrofolate deformylase activity
O9K61_RS06905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
O9K61_RS06915	COG1764	response to oxidative stress
O9K61_RS06920	COG1846	Transcriptional regulator
O9K61_RS06925	COG1764	response to oxidative stress
O9K61_RS06940	COG0457	Tetratricopeptide repeat
O9K61_RS06940	COG0463	Glycosyl transferase, family 2
O9K61_RS06950	COG2814	Major facilitator Superfamily
O9K61_RS06955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
O9K61_RS06965	COG1404	Belongs to the peptidase S8 family
O9K61_RS06970	COG1366	Belongs to the anti-sigma-factor antagonist family
O9K61_RS06975	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
O9K61_RS06980	COG1122	ATPase activity
O9K61_RS06985	COG4721	ABC-type cobalt transport system, permease component
O9K61_RS06990	COG3858	chitin binding
O9K61_RS06990	COG1388	LysM domain
O9K61_RS07000	COG2239	Acts as a magnesium transporter
O9K61_RS07005	COG0789	Transcriptional regulator
O9K61_RS07020	COG1846	Transcriptional regulator
O9K61_RS07025	COG0726	polysaccharide deacetylase
O9K61_RS07030	COG1793	dna ligase
O9K61_RS07030	COG3285	dna ligase
O9K61_RS07035	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
O9K61_RS07040	COG0586	Pfam SNARE associated Golgi protein
O9K61_RS07050	COG1191	sigma factor activity
O9K61_RS07075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
O9K61_RS07080	COG2323	membrane
O9K61_RS07090	COG3594	Acyltransferase
O9K61_RS07095	COG5002	protein histidine kinase activity
O9K61_RS07100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
O9K61_RS07120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
O9K61_RS07125	COG0436	Aminotransferase
O9K61_RS07155	COG3852	Histidine kinase
O9K61_RS07160	COG1846	Transcriptional regulator
O9K61_RS07165	COG1360	Flagellar Motor Protein
O9K61_RS07170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
O9K61_RS07175	COG0542	response to heat
O9K61_RS07180	COG3949	Membrane
O9K61_RS07195	COG0720	synthase
O9K61_RS07200	COG0602	queuosine metabolic process
O9K61_RS07210	COG1733	regulation of RNA biosynthetic process
O9K61_RS07215	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS07225	COG1388	LysM domain
O9K61_RS07225	COG4641	Protein conserved in bacteria
O9K61_RS07230	COG1388	LysM domain
O9K61_RS07235	COG3858	chitin binding
O9K61_RS07245	COG4873	Protein conserved in bacteria
O9K61_RS07255	COG3773	Cell wall hydrolase
O9K61_RS07260	COG2244	polysaccharide biosynthetic process
O9K61_RS07265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O9K61_RS07270	COG2217	Heavy metal translocating P-type atpase
O9K61_RS07275	COG0006	proline dipeptidase activity
O9K61_RS07285	COG1609	Transcriptional regulator
O9K61_RS07290	COG3711	transcriptional antiterminator
O9K61_RS07295	COG1263	PTS System
O9K61_RS07295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O9K61_RS07295	COG2190	(PTS) system
O9K61_RS07300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
O9K61_RS07305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
O9K61_RS07315	COG1533	DNA photolyase activity
O9K61_RS07320	COG0840	transmembrane signaling receptor activity
O9K61_RS07325	COG2084	Dehydrogenase
O9K61_RS07330	COG2340	Cysteine-rich secretory protein family
O9K61_RS07335	COG0768	penicillin binding
O9K61_RS07340	COG4191	Histidine kinase
O9K61_RS07345	COG0436	Aminotransferase
O9K61_RS07355	COG0784	Response regulator, receiver
O9K61_RS07355	COG0835	chemotaxis
O9K61_RS07365	COG2814	Major facilitator Superfamily
O9K61_RS07370	COG1376	ErfK ybiS ycfS ynhG family protein
O9K61_RS07375	COG1408	metallophosphoesterase
O9K61_RS07380	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS07390	COG2200	EAL domain
O9K61_RS07395	COG4703	Protein of unknown function (DUF1797)
O9K61_RS07400	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
O9K61_RS07410	COG0517	IMP dehydrogenase activity
O9K61_RS07415	COG0583	DNA-binding transcription factor activity
O9K61_RS07420	COG0716	FMN binding
O9K61_RS07430	COG0716	FMN binding
O9K61_RS07450	COG0668	transmembrane transport
O9K61_RS07455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O9K61_RS07475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
O9K61_RS07480	COG0303	'Molybdopterin
O9K61_RS07485	COG1763	Mo-molybdopterin cofactor biosynthetic process
O9K61_RS07490	COG0314	molybdopterin synthase activity
O9K61_RS07495	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
O9K61_RS07505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
O9K61_RS07510	COG1136	(ABC) transporter
O9K61_RS07515	COG0577	efflux transmembrane transporter activity
O9K61_RS07520	COG1349	DNA-binding transcription factor activity
O9K61_RS07525	COG1105	Belongs to the carbohydrate kinase PfkB family
O9K61_RS07530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O9K61_RS07530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O9K61_RS07530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O9K61_RS07535	COG0681	Belongs to the peptidase S26 family
O9K61_RS07545	COG0488	(ABC) transporter
O9K61_RS07550	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
O9K61_RS07555	COG2309	aminopeptidase activity
O9K61_RS07565	COG1077	Cell shape determining protein MreB Mrl
O9K61_RS07570	COG2002	toxin-antitoxin pair type II binding
O9K61_RS07575	COG3852	Histidine kinase
O9K61_RS07580	COG2105	PFAM AIG2 family protein
O9K61_RS07580	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
O9K61_RS07585	COG0569	domain protein
O9K61_RS07600	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
O9K61_RS07610	COG0561	phosphatase activity
O9K61_RS07615	COG0242	peptide deformylase activity
O9K61_RS07625	COG0497	DNA recombination
O9K61_RS07635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS07635	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS07635	COG3321	synthase
O9K61_RS07635	COG4221	oxidoreductase activity
O9K61_RS07640	COG4221	oxidoreductase activity
O9K61_RS07640	COG0300	oxidoreductase activity
O9K61_RS07640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O9K61_RS07640	COG3321	synthase
O9K61_RS07645	COG4221	oxidoreductase activity
O9K61_RS07645	COG3321	synthase
O9K61_RS07645	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS07645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS07650	COG4221	oxidoreductase activity
O9K61_RS07650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O9K61_RS07650	COG0300	oxidoreductase activity
O9K61_RS07650	COG3321	synthase
O9K61_RS07655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O9K61_RS07655	COG0300	oxidoreductase activity
O9K61_RS07655	COG3321	synthase
O9K61_RS07655	COG4221	oxidoreductase activity
O9K61_RS07660	COG4221	oxidoreductase activity
O9K61_RS07660	COG3321	synthase
O9K61_RS07660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O9K61_RS07660	COG0300	oxidoreductase activity
O9K61_RS07665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS07665	COG4221	oxidoreductase activity
O9K61_RS07665	COG3321	synthase
O9K61_RS07665	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS07670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O9K61_RS07675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
O9K61_RS07680	COG0022	dehydrogenase e1 component
O9K61_RS07685	COG0508	dehydrogenase complex catalyzes the overall conversion of
O9K61_RS07690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
O9K61_RS07695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O9K61_RS07710	COG1982	Orn Lys Arg decarboxylase major
O9K61_RS07730	COG0483	inositol monophosphate 1-phosphatase activity
O9K61_RS07740	COG3227	Zinc metalloprotease (Elastase)
O9K61_RS07745	COG1595	DNA-templated transcription, initiation
O9K61_RS07765	COG1217	gtp-binding protein TYPA
O9K61_RS07775	COG4896	Protein conserved in bacteria
O9K61_RS07785	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
O9K61_RS07790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
O9K61_RS07795	COG2066	Belongs to the glutaminase family
O9K61_RS07805	COG0772	Belongs to the SEDS family
O9K61_RS07810	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
O9K61_RS07825	COG2010	Cytochrome c
O9K61_RS07825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
O9K61_RS07830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
O9K61_RS07835	COG1845	cytochrome c oxidase, subunit III
O9K61_RS07840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
O9K61_RS07845	COG3336	cytochrome c oxidase
O9K61_RS07860	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
O9K61_RS07865	COG2340	Cysteine-rich secretory protein family
O9K61_RS07880	COG3679	Belongs to the UPF0342 family
O9K61_RS07895	COG0742	ribosomal rna small subunit methyltransferase
O9K61_RS07905	COG3314	Sporulation integral membrane protein YlbJ
O9K61_RS07910	COG1752	Esterase of the alpha-beta hydrolase superfamily
O9K61_RS07915	COG3480	Lon protease (S16) C-terminal proteolytic domain
O9K61_RS07925	COG1399	metal-binding, possibly nucleic acid-binding protein
O9K61_RS07945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
O9K61_RS07965	COG4839	cell division protein FtsL
O9K61_RS07970	COG0768	penicillin binding
O9K61_RS07975	COG0768	penicillin binding
O9K61_RS07995	COG0772	Belongs to the SEDS family
O9K61_RS08010	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
O9K61_RS08015	COG0849	cell division
O9K61_RS08020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
O9K61_RS08025	COG1404	Belongs to the peptidase S8 family
O9K61_RS08025	COG4412	M6 family metalloprotease domain protein
O9K61_RS08035	COG1191	sigma factor activity
O9K61_RS08040	COG1191	sigma factor activity
O9K61_RS08045	COG1119	ATPase activity
O9K61_RS08050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O9K61_RS08055	COG1873	PFAM PRC-barrel domain
O9K61_RS08060	COG1496	oxidoreductase activity
O9K61_RS08065	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
O9K61_RS08075	COG0762	integral membrane protein
O9K61_RS08080	COG2302	S4 RNA-binding domain
O9K61_RS08085	COG3599	regulation of cell shape
O9K61_RS08090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
O9K61_RS08095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
O9K61_RS08105	COG0564	pseudouridine synthase activity
O9K61_RS08115	COG2233	PERMEase
O9K61_RS08125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
O9K61_RS08130	COG0505	Belongs to the CarA family
O9K61_RS08135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
O9K61_RS08150	COG0284	orotidine-5'-phosphate decarboxylase activity
O9K61_RS08155	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
O9K61_RS08165	COG0306	phosphate transporter
O9K61_RS08180	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
O9K61_RS08185	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
O9K61_RS08190	COG1648	precorrin-2 dehydrogenase activity
O9K61_RS08200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
O9K61_RS08205	COG1561	YicC-like family, N-terminal region
O9K61_RS08215	COG0194	GDP metabolic process
O9K61_RS08225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
O9K61_RS08230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
O9K61_RS08235	COG0242	peptide deformylase activity
O9K61_RS08245	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
O9K61_RS08245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
O9K61_RS08255	COG0631	protein serine/threonine phosphatase activity
O9K61_RS08260	COG0515	serine threonine protein kinase
O9K61_RS08260	COG2815	serine threonine protein kinase
O9K61_RS08270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
O9K61_RS08275	COG1564	THIamine pyrophosphokinase
O9K61_RS08290	COG1302	Protein conserved in bacteria
O9K61_RS08295	COG1461	Dihydroxyacetone kinase
O9K61_RS08300	COG1760	l-serine dehydratase
O9K61_RS08305	COG1760	l-serine dehydratase
O9K61_RS08310	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
O9K61_RS08325	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
O9K61_RS08330	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS08345	COG1196	nuclear chromosome segregation
O9K61_RS08350	COG0552	protein localization to endoplasmic reticulum
O9K61_RS08365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
O9K61_RS08375	COG1837	Belongs to the UPF0109 family
O9K61_RS08400	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
O9K61_RS08415	COG2257	FlhB HrpN YscU SpaS Family
O9K61_RS08425	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
O9K61_RS08430	COG0758	DNA mediated transformation
O9K61_RS08435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
O9K61_RS08445	COG4974	Belongs to the 'phage' integrase family
O9K61_RS08465	COG1815	bacterial-type flagellum-dependent cell motility
O9K61_RS08470	COG1558	bacterial-type flagellum-dependent cell motility
O9K61_RS08475	COG1677	Flagellar hook-basal body complex protein FliE
O9K61_RS08480	COG1766	The M ring may be actively involved in energy transduction
O9K61_RS08485	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
O9K61_RS08490	COG1317	bacterial-type flagellum organization
O9K61_RS08495	COG1157	protein secretion by the type III secretion system
O9K61_RS08500	COG2882	bacterial-type flagellum organization
O9K61_RS08505	COG3334	PFAM MgtE intracellular
O9K61_RS08510	COG3144	bacterial-type flagellum assembly
O9K61_RS08515	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
O9K61_RS08520	COG4786	Flagellar basal body rod
O9K61_RS08525	COG1582	Flagellar protein (FlbD)
O9K61_RS08530	COG1580	Controls the rotational direction of flagella during chemotaxis
O9K61_RS08535	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
O9K61_RS08540	COG1776	CheC inhibitor of MCP methylation
O9K61_RS08540	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
O9K61_RS08545	COG2201	protein-glutamate methylesterase activity
O9K61_RS08550	COG3190	flagellar
O9K61_RS08555	COG1338	Plays a role in the flagellum-specific transport system
O9K61_RS08560	COG1987	bacterial-type flagellum assembly
O9K61_RS08565	COG1684	flagellar biosynthetic protein fliR
O9K61_RS08570	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
O9K61_RS08575	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
O9K61_RS08580	COG1419	protein localization to endoplasmic reticulum
O9K61_RS08585	COG0455	bacterial-type flagellum organization
O9K61_RS08590	COG2201	protein-glutamate methylesterase activity
O9K61_RS08595	COG2198	Histidine kinase
O9K61_RS08595	COG0643	Histidine kinase
O9K61_RS08600	COG0835	chemotaxis
O9K61_RS08605	COG1776	CheC inhibitor of MCP methylation
O9K61_RS08615	COG1191	sigma factor activity
O9K61_RS08645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
O9K61_RS08650	COG4589	Belongs to the CDS family
O9K61_RS08660	COG0750	zinc metalloprotease
O9K61_RS08680	COG0195	Participates in both transcription termination and antitermination
O9K61_RS08685	COG2740	Nucleic-acid-binding protein implicated in transcription termination
O9K61_RS08690	COG1358	cellular component organization or biogenesis
O9K61_RS08700	COG1550	Protein conserved in bacteria
O9K61_RS08715	COG0196	riboflavin kinase activity
O9K61_RS08730	COG0726	polysaccharide deacetylase
O9K61_RS08735	COG0612	Peptidase, M16
O9K61_RS08740	COG1873	PFAM PRC-barrel domain
O9K61_RS08745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
O9K61_RS08750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
O9K61_RS08755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
O9K61_RS08760	COG0527	aspartate kinase activity
O9K61_RS08770	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
O9K61_RS08775	COG0740	serine-type endopeptidase activity
O9K61_RS08785	COG1674	ftsk spoiiie
O9K61_RS08785	COG4980	gas vesicle protein
O9K61_RS08790	COG2188	Transcriptional regulator
O9K61_RS08795	COG2814	Major facilitator Superfamily
O9K61_RS08800	COG1846	Transcriptional regulator
O9K61_RS08805	COG1033	growth of symbiont in host cell
O9K61_RS08805	COG2409	Drug exporters of the RND superfamily
O9K61_RS08810	COG0612	Peptidase, M16
O9K61_RS08815	COG0612	Peptidase, M16
O9K61_RS08820	COG0300	oxidoreductase activity
O9K61_RS08835	COG1426	Protein conserved in bacteria
O9K61_RS08840	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
O9K61_RS08855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
O9K61_RS08865	COG1692	metallophosphoesterase
O9K61_RS08870	COG2359	stage V sporulation protein S
O9K61_RS08890	COG4550	Control of competence regulator ComK, YlbF/YmcA
O9K61_RS08910	COG0582	viral genome integration into host DNA
O9K61_RS08945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O9K61_RS08950	COG3425	synthase
O9K61_RS08955	COG1024	Enoyl-CoA hydratase
O9K61_RS08960	COG1024	Enoyl-CoA hydratase
O9K61_RS08965	COG0300	oxidoreductase activity
O9K61_RS08965	COG3321	synthase
O9K61_RS08965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS08965	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS08965	COG0318	PFAM AMP-dependent synthetase and ligase
O9K61_RS08970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O9K61_RS08970	COG0300	oxidoreductase activity
O9K61_RS08970	COG3321	synthase
O9K61_RS08970	COG4221	oxidoreductase activity
O9K61_RS08975	COG3321	synthase
O9K61_RS08975	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS08975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS08975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O9K61_RS08975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O9K61_RS08975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O9K61_RS08975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O9K61_RS08975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS08975	COG3321	synthase
O9K61_RS08975	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS08980	COG4221	oxidoreductase activity
O9K61_RS08980	COG3321	synthase
O9K61_RS08980	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS08980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS08985	COG3321	synthase
O9K61_RS08985	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
O9K61_RS08985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
O9K61_RS08985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O9K61_RS08990	COG2124	cytochrome p450
O9K61_RS08995	COG3209	COG3209 Rhs family protein
O9K61_RS09000	COG3619	membrane
O9K61_RS09010	COG1404	Belongs to the peptidase S8 family
O9K61_RS09020	COG4195	phage-related replication protein
O9K61_RS09025	COG1764	response to oxidative stress
O9K61_RS09035	COG2076	Multidrug Resistance protein
O9K61_RS09075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
O9K61_RS09080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
O9K61_RS09085	COG4112	unkown
O9K61_RS09090	COG0860	N-Acetylmuramoyl-L-alanine amidase
O9K61_RS09095	COG0464	growth
O9K61_RS09100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
O9K61_RS09105	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
O9K61_RS09110	COG0789	Transcriptional regulator
O9K61_RS09115	COG0174	glutamine synthetase
O9K61_RS09125	COG2211	Major facilitator Superfamily
O9K61_RS09130	COG3507	Belongs to the glycosyl hydrolase 43 family
O9K61_RS09145	COG1070	Carbohydrate kinase
O9K61_RS09150	COG0574	Belongs to the PEP-utilizing enzyme family
O9K61_RS09150	COG3848	Pyruvate phosphate dikinase
O9K61_RS09170	COG2318	DinB family
O9K61_RS09175	COG1064	alcohol dehydrogenase
O9K61_RS09190	COG0456	acetyltransferase
O9K61_RS09220	COG3397	chitin binding
O9K61_RS09230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O9K61_RS09245	COG5434	Belongs to the glycosyl hydrolase 28 family
O9K61_RS09250	COG0756	dUTP diphosphatase activity
O9K61_RS09255	COG4195	phage-related replication protein
O9K61_RS09290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
O9K61_RS09300	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
O9K61_RS09320	COG0785	Cytochrome C biogenesis protein
O9K61_RS09325	COG2201	protein-glutamate methylesterase activity
O9K61_RS09330	COG4846	Membrane protein involved in cytochrome C biogenesis
O9K61_RS09340	COG0071	Belongs to the small heat shock protein (HSP20) family
O9K61_RS09355	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
O9K61_RS09360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O9K61_RS09380	COG0824	Thioesterase
O9K61_RS09390	COG4841	protein insertion into membrane
O9K61_RS09400	COG1832	CoA-binding protein
O9K61_RS09405	COG0187	DNA topoisomerase II activity
O9K61_RS09410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
O9K61_RS09425	COG1115	amino acid carrier protein
O9K61_RS09435	COG1063	alcohol dehydrogenase
O9K61_RS09440	COG0800	Aldolase
O9K61_RS09445	COG1312	Catalyzes the dehydration of D-mannonate
O9K61_RS09450	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS09455	COG1609	Transcriptional regulator
O9K61_RS09460	COG2271	Major facilitator Superfamily
O9K61_RS09500	COG2205	protein histidine kinase activity
O9K61_RS09505	COG0745	RESPONSE REGULATOR receiver
O9K61_RS09515	COG3507	Belongs to the glycosyl hydrolase 43 family
O9K61_RS09540	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS09545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
O9K61_RS09550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
O9K61_RS09555	COG2610	gluconate transmembrane transporter activity
O9K61_RS09560	COG2124	cytochrome p450
O9K61_RS09580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
O9K61_RS09590	COG2246	polysaccharide biosynthetic process
O9K61_RS09595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
O9K61_RS09600	COG0586	Pfam SNARE associated Golgi protein
O9K61_RS09605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
O9K61_RS09610	COG1024	Enoyl-CoA hydratase
O9K61_RS09615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
O9K61_RS09620	COG0511	ligase activity, forming carbon-carbon bonds
O9K61_RS09625	COG0439	Biotin carboxylase
O9K61_RS09630	COG0318	PFAM AMP-dependent synthetase and ligase
O9K61_RS09635	COG1960	acyl-CoA dehydrogenase activity
O9K61_RS09640	COG1649	PFAM Uncharacterised BCR, COG1649
O9K61_RS09650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS09650	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
O9K61_RS09655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS09660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS09665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS09670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS09675	COG2027	D-alanyl-D-alanine carboxypeptidase
O9K61_RS09680	COG2017	converts alpha-aldose to the beta-anomer
O9K61_RS09685	COG0534	Mate efflux family protein
O9K61_RS09700	COG0582	viral genome integration into host DNA
O9K61_RS09705	COG0166	Belongs to the GPI family
O9K61_RS09710	COG0405	Gamma-glutamyltransferase
O9K61_RS09715	COG2814	Major facilitator Superfamily
O9K61_RS09720	COG0640	Transcriptional regulator
O9K61_RS09725	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
O9K61_RS09735	COG0604	alcohol dehydrogenase
O9K61_RS09745	COG0493	'glutamate synthase
O9K61_RS09750	COG0067	glutamate synthase
O9K61_RS09750	COG0069	glutamate synthase activity
O9K61_RS09750	COG0070	glutamate synthase
O9K61_RS09755	COG0583	DNA-binding transcription factor activity
O9K61_RS09760	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
O9K61_RS09775	COG0300	oxidoreductase activity
O9K61_RS09780	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
O9K61_RS09790	COG2814	Major facilitator Superfamily
O9K61_RS09795	COG1070	Carbohydrate kinase
O9K61_RS09800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
O9K61_RS09805	COG0243	molybdopterin cofactor binding
O9K61_RS09840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O9K61_RS09845	COG0662	Cupin 2, conserved barrel domain protein
O9K61_RS09845	COG2207	Transcriptional regulator
O9K61_RS09850	COG1309	transcriptional regulator
O9K61_RS09855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O9K61_RS09865	COG0640	Transcriptional regulator
O9K61_RS09870	COG0741	lytic transglycosylase activity
O9K61_RS09875	COG2322	membrane
O9K61_RS09890	COG1619	proteins homologs of microcin C7 resistance protein MccF
O9K61_RS09900	COG1388	LysM domain
O9K61_RS09900	COG3584	3D domain protein
O9K61_RS09905	COG0514	ATP-dependent DNA helicase (RecQ)
O9K61_RS09915	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
O9K61_RS09920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
O9K61_RS09935	COG0071	Belongs to the small heat shock protein (HSP20) family
O9K61_RS09965	COG1012	belongs to the aldehyde dehydrogenase family
O9K61_RS09970	COG1657	PFAM Prenyltransferase squalene oxidase
O9K61_RS09975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
O9K61_RS09980	COG0733	neurotransmitter:sodium symporter activity
O9K61_RS09985	COG0385	Bile acid
O9K61_RS09990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O9K61_RS09995	COG0508	dehydrogenase complex catalyzes the overall conversion of
O9K61_RS10005	COG4548	von Willebrand factor, type A
O9K61_RS10010	COG0714	Associated with various cellular activities
O9K61_RS10015	COG2032	superoxide dismutase activity
O9K61_RS10020	COG1388	LysM domain
O9K61_RS10020	COG0791	NLP P60 protein
O9K61_RS10025	COG1819	glycosyl
O9K61_RS10030	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
O9K61_RS10035	COG0534	Mate efflux family protein
O9K61_RS10040	COG1366	Belongs to the anti-sigma-factor antagonist family
O9K61_RS10045	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
O9K61_RS10050	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
O9K61_RS10060	COG2962	Rard protein
O9K61_RS10075	COG1942	4-Oxalocrotonate Tautomerase
O9K61_RS10085	COG1733	regulation of RNA biosynthetic process
O9K61_RS10090	COG0778	Nitroreductase
O9K61_RS10095	COG0400	carboxylic ester hydrolase activity
O9K61_RS10100	COG0346	lactoylglutathione lyase activity
O9K61_RS10110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
O9K61_RS10130	COG3409	Peptidoglycan-binding domain 1 protein
O9K61_RS10130	COG0793	Belongs to the peptidase S41A family
O9K61_RS10135	COG2226	methyltransferase
O9K61_RS10145	COG1876	peptidase activity
O9K61_RS10165	COG0671	phosphoesterase, PA-phosphatase related
O9K61_RS10200	COG1509	lysine 2,3-aminomutase activity
O9K61_RS10205	COG0456	acetyltransferase
O9K61_RS10210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O9K61_RS10215	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
O9K61_RS10220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
O9K61_RS10225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
O9K61_RS10230	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
O9K61_RS10240	COG0456	acetyltransferase
O9K61_RS10245	COG0463	Glycosyl transferase, family 2
O9K61_RS10260	COG4641	Protein conserved in bacteria
O9K61_RS10270	COG1086	Polysaccharide biosynthesis protein
O9K61_RS10295	COG1388	LysM domain
O9K61_RS10300	COG0457	Tetratricopeptide repeat
O9K61_RS10320	COG5444	nuclease activity
O9K61_RS10325	COG4282	regulation of fungal-type cell wall biogenesis
O9K61_RS10330	COG1525	nuclease
O9K61_RS10335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
O9K61_RS10355	COG1846	Transcriptional regulator
O9K61_RS10360	COG4698	Protein conserved in bacteria
O9K61_RS10365	COG2755	lipolytic protein G-D-S-L family
O9K61_RS10370	COG1999	signal sequence binding
O9K61_RS10380	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
O9K61_RS10385	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
O9K61_RS10390	COG1272	protein, Hemolysin III
O9K61_RS10395	COG0204	Acyl-transferase
O9K61_RS10400	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
O9K61_RS10415	COG2521	methyltransferase
O9K61_RS10415	COG2136	Putative SAM-dependent methyltransferase
O9K61_RS10430	COG1413	lyase activity
O9K61_RS10435	COG1418	mRNA catabolic process
O9K61_RS10440	COG0386	Belongs to the glutathione peroxidase family
O9K61_RS10450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
O9K61_RS10460	COG1278	Cold shock
O9K61_RS10480	COG0328	RNA-DNA hybrid ribonuclease activity
O9K61_RS10485	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
O9K61_RS10490	COG0328	RNA-DNA hybrid ribonuclease activity
O9K61_RS10500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
O9K61_RS10515	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
O9K61_RS10525	COG1755	Isoprenylcysteine carboxyl methyltransferase
O9K61_RS10530	COG3424	synthase
O9K61_RS10555	COG1335	isochorismatase
O9K61_RS10565	COG2233	PERMEase
O9K61_RS10575	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
O9K61_RS10580	COG1199	ATP-dependent helicase activity
O9K61_RS10595	COG0116	Belongs to the methyltransferase superfamily
O9K61_RS10625	COG3359	exonuclease
O9K61_RS10630	COG1111	helicase
O9K61_RS10630	COG1205	dead DEAH box helicase
O9K61_RS10635	COG2190	(PTS) system
O9K61_RS10640	COG0071	Belongs to the small heat shock protein (HSP20) family
O9K61_RS10680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O9K61_RS10680	COG4499	WXG100 protein secretion system (Wss), protein YukC
O9K61_RS10690	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
O9K61_RS10695	COG3935	DnaD domain protein
O9K61_RS10705	COG0436	Aminotransferase
O9K61_RS10710	COG5353	protein conserved in bacteria
O9K61_RS10720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
O9K61_RS10720	COG1199	ATP-dependent helicase activity
O9K61_RS10750	COG0438	transferase activity, transferring glycosyl groups
O9K61_RS10755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
O9K61_RS10770	COG1694	Mazg nucleotide pyrophosphohydrolase
O9K61_RS10775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O9K61_RS10780	COG2140	Oxalate decarboxylase
O9K61_RS10790	COG4347	Protein of unknown function (DUF1405)
O9K61_RS10795	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
O9K61_RS10795	COG2010	Cytochrome c
O9K61_RS10800	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
O9K61_RS10805	COG0723	plastoquinol--plastocyanin reductase activity
O9K61_RS10820	COG0457	Tetratricopeptide repeat
O9K61_RS10830	COG0287	Prephenate dehydrogenase
O9K61_RS10865	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
O9K61_RS10870	COG4401	Chorismate mutase type I
O9K61_RS10885	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
O9K61_RS10890	COG0105	UTP biosynthetic process
O9K61_RS10895	COG0142	geranyltranstransferase activity
O9K61_RS10905	COG0142	geranyltranstransferase activity
O9K61_RS10920	COG0776	regulation of translation
O9K61_RS10925	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
O9K61_RS10965	COG0539	negative regulation of cytoplasmic translation
O9K61_RS10980	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
O9K61_RS10985	COG2959	enzyme of heme biosynthesis
O9K61_RS10990	COG3409	Peptidoglycan-binding domain 1 protein
O9K61_RS10990	COG3773	Cell wall hydrolase
O9K61_RS10995	COG2339	peptidase activity
O9K61_RS11000	COG0492	ferredoxin-NADP+ reductase activity
O9K61_RS11005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
O9K61_RS11010	COG4862	establishment of competence for transformation
O9K61_RS11015	COG1408	metallophosphoesterase
O9K61_RS11025	COG1388	LysM domain
O9K61_RS11030	COG1266	CAAX protease self-immunity
O9K61_RS11035	COG0514	ATP-dependent DNA helicase (RecQ)
O9K61_RS11040	COG4955	Helix-turn-helix domain
O9K61_RS11045	COG1141	Ferredoxin
O9K61_RS11050	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
O9K61_RS11055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
O9K61_RS11065	COG1595	DNA-templated transcription, initiation
O9K61_RS11070	COG5002	protein histidine kinase activity
O9K61_RS11075	COG0745	RESPONSE REGULATOR receiver
O9K61_RS11080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
O9K61_RS11085	COG1333	cytochrome c biogenesis protein
O9K61_RS11090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O9K61_RS11095	COG1187	pseudouridine synthase activity
O9K61_RS11100	COG0700	Nucleoside recognition
O9K61_RS11105	COG2715	membrane protein required for spore maturation
O9K61_RS11110	COG1686	Belongs to the peptidase S11 family
O9K61_RS11135	COG1547	Domain of unknown function (DUF309)
O9K61_RS11140	COG0456	acetyltransferase
O9K61_RS11155	COG0307	riboflavin synthase, alpha
O9K61_RS11160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
O9K61_RS11160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
O9K61_RS11170	COG0681	Belongs to the peptidase S26 family
O9K61_RS11180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
O9K61_RS11185	COG4086	secreted protein
O9K61_RS11190	COG0019	diaminopimelate decarboxylase activity
O9K61_RS11195	COG0697	spore germination
O9K61_RS11210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
O9K61_RS11230	COG1191	sigma factor activity
O9K61_RS11240	COG1366	Belongs to the anti-sigma-factor antagonist family
O9K61_RS11245	COG1686	Belongs to the peptidase S11 family
O9K61_RS11250	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
O9K61_RS11255	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
O9K61_RS11260	COG4974	Belongs to the 'phage' integrase family
O9K61_RS11270	COG0735	belongs to the Fur family
O9K61_RS11275	COG1300	Membrane
O9K61_RS11290	COG0281	malic enzyme
O9K61_RS11295	COG1757	Na H antiporter
O9K61_RS11300	COG1027	Aspartate ammonia-lyase
O9K61_RS11305	COG0252	asparaginase activity
O9K61_RS11310	COG1396	sequence-specific DNA binding
O9K61_RS11315	COG1379	DNA repair
O9K61_RS11320	COG0494	nUDIX hydrolase
O9K61_RS11330	COG0667	Aldo Keto reductase
O9K61_RS11340	COG1073	alpha beta
O9K61_RS11350	COG4918	Iron-sulphur cluster biosynthesis
O9K61_RS11355	COG0456	acetyltransferase
O9K61_RS11355	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
O9K61_RS11360	COG2329	Antibiotic biosynthesis monooxygenase
O9K61_RS11365	COG0456	acetyltransferase
O9K61_RS11370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
O9K61_RS11385	COG0628	permease
O9K61_RS11395	COG0346	lactoylglutathione lyase activity
O9K61_RS11405	COG3048	D-serine ammonia-lyase activity
O9K61_RS11410	COG0300	oxidoreductase activity
O9K61_RS11415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O9K61_RS11420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
O9K61_RS11425	COG1024	Enoyl-CoA hydratase
O9K61_RS11430	COG3425	synthase
O9K61_RS11435	COG2124	cytochrome p450
O9K61_RS11440	COG3321	synthase
O9K61_RS11440	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS11440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O9K61_RS11440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O9K61_RS11440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS11445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O9K61_RS11445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O9K61_RS11445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS11445	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS11445	COG3321	synthase
O9K61_RS11450	COG0300	oxidoreductase activity
O9K61_RS11450	COG0318	PFAM AMP-dependent synthetase and ligase
O9K61_RS11450	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS11450	COG3321	synthase
O9K61_RS11450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS11455	COG0300	oxidoreductase activity
O9K61_RS11455	COG0318	PFAM AMP-dependent synthetase and ligase
O9K61_RS11455	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS11455	COG3321	synthase
O9K61_RS11455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS11460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O9K61_RS11460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS11460	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS11460	COG3321	synthase
O9K61_RS11460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O9K61_RS11465	COG3321	synthase
O9K61_RS11465	COG0318	PFAM AMP-dependent synthetase and ligase
O9K61_RS11465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS11465	COG0300	oxidoreductase activity
O9K61_RS11465	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS11470	COG3321	synthase
O9K61_RS11470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
O9K61_RS11470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O9K61_RS11470	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS11470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS11475	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS11480	COG0318	PFAM AMP-dependent synthetase and ligase
O9K61_RS11495	COG2070	2-Nitropropane dioxygenase
O9K61_RS11495	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
O9K61_RS11500	COG0250	Participates in transcription elongation, termination and antitermination
O9K61_RS11520	COG0596	Alpha beta hydrolase
O9K61_RS11535	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
O9K61_RS11540	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
O9K61_RS11555	COG0706	membrane insertase activity
O9K61_RS11560	COG2195	Cleaves the N-terminal amino acid of tripeptides
O9K61_RS11565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
O9K61_RS11570	COG0346	lactoylglutathione lyase activity
O9K61_RS11580	COG1376	ErfK ybiS ycfS ynhG family protein
O9K61_RS11585	COG4129	membrane
O9K61_RS11590	COG1126	abc transporter atp-binding protein
O9K61_RS11595	COG0765	amino acid transport
O9K61_RS11600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O9K61_RS11610	COG1597	lipid kinase activity
O9K61_RS11615	COG0508	dehydrogenase complex catalyzes the overall conversion of
O9K61_RS11620	COG0022	dehydrogenase e1 component
O9K61_RS11625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
O9K61_RS11630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
O9K61_RS11635	COG3426	butyrate kinase activity
O9K61_RS11640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
O9K61_RS11645	COG0280	phosphate acetyltransferase
O9K61_RS11650	COG3829	transcription factor binding
O9K61_RS11650	COG3290	protein histidine kinase activity
O9K61_RS11660	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
O9K61_RS11665	COG2079	MmgE PrpD family protein
O9K61_RS11670	COG0372	Belongs to the citrate synthase family
O9K61_RS11675	COG1960	acyl-CoA dehydrogenase activity
O9K61_RS11680	COG1250	3-hydroxyacyl-CoA dehydrogenase
O9K61_RS11685	COG0183	Belongs to the thiolase family
O9K61_RS11690	COG0584	glycerophosphoryl diester phosphodiesterase
O9K61_RS11695	COG0860	N-Acetylmuramoyl-L-alanine amidase
O9K61_RS11720	COG1902	pentaerythritol trinitrate reductase activity
O9K61_RS11735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
O9K61_RS11740	COG0745	RESPONSE REGULATOR receiver
O9K61_RS11745	COG0750	zinc metalloprotease
O9K61_RS11750	COG0497	DNA recombination
O9K61_RS11760	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
O9K61_RS11770	COG0142	geranyltranstransferase activity
O9K61_RS11780	COG1570	exodeoxyribonuclease VII activity
O9K61_RS11795	COG1302	Protein conserved in bacteria
O9K61_RS11800	COG0439	Biotin carboxylase
O9K61_RS11805	COG0511	ligase activity, forming carbon-carbon bonds
O9K61_RS11845	COG3854	ATPases associated with a variety of cellular activities
O9K61_RS11860	COG0006	proline dipeptidase activity
O9K61_RS11870	COG3872	metal-dependent enzyme
O9K61_RS11880	COG1752	Esterase of the alpha-beta hydrolase superfamily
O9K61_RS11895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
O9K61_RS11915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
O9K61_RS11930	COG1396	sequence-specific DNA binding
O9K61_RS11940	COG0681	Belongs to the peptidase S26 family
O9K61_RS11965	COG4940	Competence protein ComGF
O9K61_RS11970	COG4940	Competence protein ComGF
O9K61_RS11980	COG4970	Tfp pilus assembly protein FimT
O9K61_RS11985	COG4537	Required for transformation and DNA binding
O9K61_RS11990	COG1459	type II secretion system
O9K61_RS11995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
O9K61_RS12000	COG0598	Magnesium transport protein CorA
O9K61_RS12005	COG1253	flavin adenine dinucleotide binding
O9K61_RS12010	COG1366	Belongs to the anti-sigma-factor antagonist family
O9K61_RS12020	COG1393	Belongs to the ArsC family
O9K61_RS12030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O9K61_RS12040	COG0011	TIGRFAM Protein of
O9K61_RS12050	COG2866	Carboxypeptidase
O9K61_RS12055	COG1940	carbohydrate kinase activity
O9K61_RS12060	COG4483	Protein conserved in bacteria
O9K61_RS12065	COG1757	Na H antiporter
O9K61_RS12075	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
O9K61_RS12090	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
O9K61_RS12095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
O9K61_RS12100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
O9K61_RS12105	COG0581	inorganic phosphate transmembrane transporter activity
O9K61_RS12110	COG0573	inorganic phosphate transmembrane transporter activity
O9K61_RS12115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
O9K61_RS12120	COG0768	penicillin binding
O9K61_RS12125	COG0477	Major facilitator Superfamily
O9K61_RS12130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
O9K61_RS12135	COG2839	Protein conserved in bacteria
O9K61_RS12140	COG5521	maltodextrose utilization protein MalA
O9K61_RS12145	COG1388	LysM domain
O9K61_RS12155	COG4709	membrane
O9K61_RS12160	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
O9K61_RS12165	COG0735	belongs to the Fur family
O9K61_RS12170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O9K61_RS12185	COG0513	Belongs to the DEAD box helicase family
O9K61_RS12200	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
O9K61_RS12205	COG2384	SAM-dependent methyltransferase
O9K61_RS12210	COG2010	Cytochrome c
O9K61_RS12215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
O9K61_RS12220	COG0358	DNA primase activity
O9K61_RS12235	COG0517	IMP dehydrogenase activity
O9K61_RS12240	COG0751	glycine-tRNA ligase activity
O9K61_RS12260	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
O9K61_RS12265	COG0295	cytidine deaminase activity
O9K61_RS12270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
O9K61_RS12280	COG1480	7TM receptor with intracellular HD hydrolase
O9K61_RS12285	COG1702	phosphate starvation-inducible protein PhoH
O9K61_RS12290	COG0561	phosphatase activity
O9K61_RS12305	COG4864	UPF0365 protein
O9K61_RS12310	COG1030	water channel activity
O9K61_RS12315	COG1610	YqeY-like protein
O9K61_RS12325	COG1283	sodium-dependent phosphate transmembrane transporter activity
O9K61_RS12335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
O9K61_RS12340	COG1385	rRNA (uridine-N3-)-methyltransferase activity
O9K61_RS12370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
O9K61_RS12385	COG0860	N-Acetylmuramoyl-L-alanine amidase
O9K61_RS12415	COG2333	competence protein COMEC
O9K61_RS12415	COG0658	competence protein
O9K61_RS12420	COG2131	deaminase
O9K61_RS12425	COG1596	polysaccharide export
O9K61_RS12425	COG1555	photosystem II stabilization
O9K61_RS12430	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
O9K61_RS12435	COG2226	methyltransferase
O9K61_RS12440	COG0799	negative regulation of ribosome biogenesis
O9K61_RS12445	COG1713	HD superfamily hydrolase involved in NAD metabolism
O9K61_RS12455	COG1534	Rna-binding protein
O9K61_RS12460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
O9K61_RS12465	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
O9K61_RS12470	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
O9K61_RS12485	COG2755	lipolytic protein G-D-S-L family
O9K61_RS12495	COG0398	Pfam SNARE associated Golgi protein
O9K61_RS12525	COG2207	Transcriptional regulator
O9K61_RS12525	COG3708	Transcriptional regulator
O9K61_RS12535	COG0563	adenylate kinase activity
O9K61_RS12550	COG0456	acetyltransferase
O9K61_RS12555	COG2318	DinB family
O9K61_RS12565	COG0561	phosphatase activity
O9K61_RS12570	COG0561	phosphatase activity
O9K61_RS12580	COG1482	cell wall glycoprotein biosynthetic process
O9K61_RS12585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O9K61_RS12585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O9K61_RS12585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
O9K61_RS12590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O9K61_RS12590	COG3711	transcriptional antiterminator
O9K61_RS12600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
O9K61_RS12605	COG0583	DNA-binding transcription factor activity
O9K61_RS12610	COG2814	Major facilitator Superfamily
O9K61_RS12615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
O9K61_RS12615	COG2124	cytochrome p450
O9K61_RS12620	COG1309	transcriptional regulator
O9K61_RS12625	COG2226	methyltransferase
O9K61_RS12640	COG2116	formate transmembrane transporter activity
O9K61_RS12645	COG5609	conserved protein (DUF2294)
O9K61_RS12650	COG3383	formate dehydrogenase (NAD+) activity
O9K61_RS12655	COG2427	Protein of unknown function (DUF1641)
O9K61_RS12665	COG0626	cystathionine gamma-synthase activity
O9K61_RS12670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
O9K61_RS12695	COG0768	penicillin binding
O9K61_RS12710	COG0826	peptidase U32
O9K61_RS12715	COG0826	peptidase U32
O9K61_RS12720	COG4122	O-methyltransferase activity
O9K61_RS12725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
O9K61_RS12750	COG0628	permease
O9K61_RS12755	COG1126	abc transporter atp-binding protein
O9K61_RS12760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O9K61_RS12765	COG0765	amino acid transport
O9K61_RS12770	COG0765	amino acid transport
O9K61_RS12785	COG3881	PFAM PRC-barrel domain
O9K61_RS12790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
O9K61_RS12795	COG0457	Tetratricopeptide repeat
O9K61_RS12805	COG1104	cysteine desulfurase activity
O9K61_RS12810	COG1959	2 iron, 2 sulfur cluster binding
O9K61_RS12815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
O9K61_RS12820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
O9K61_RS12845	COG4991	sh3 domain protein
O9K61_RS12845	COG3103	Sh3 type 3 domain protein
O9K61_RS12845	COG0860	N-Acetylmuramoyl-L-alanine amidase
O9K61_RS12855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
O9K61_RS12865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
O9K61_RS12865	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
O9K61_RS12870	COG5416	Lipopolysaccharide assembly protein A domain
O9K61_RS12875	COG0490	domain, Protein
O9K61_RS12880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
O9K61_RS12880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
O9K61_RS12890	COG2244	polysaccharide biosynthetic process
O9K61_RS12895	COG2323	membrane
O9K61_RS12905	COG1862	Preprotein translocase
O9K61_RS12945	COG1388	LysM domain
O9K61_RS12955	COG0157	Belongs to the NadC ModD family
O9K61_RS12960	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
O9K61_RS12965	COG1104	cysteine desulfurase activity
O9K61_RS12970	COG1827	regulation of RNA biosynthetic process
O9K61_RS12975	COG0077	Prephenate dehydratase
O9K61_RS12990	COG3290	protein histidine kinase activity
O9K61_RS12995	COG0211	Belongs to the bacterial ribosomal protein bL27 family
O9K61_RS13000	COG2868	ribosomal protein
O9K61_RS13010	COG1994	Peptidase M50
O9K61_RS13015	COG0739	heme binding
O9K61_RS13020	COG2894	cell division
O9K61_RS13030	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
O9K61_RS13040	COG1077	Cell shape determining protein MreB Mrl
O9K61_RS13060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
O9K61_RS13065	COG0285	dihydrofolate synthase activity
O9K61_RS13070	COG0525	valine-tRNA ligase activity
O9K61_RS13080	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
O9K61_RS13085	COG1388	LysM domain
O9K61_RS13095	COG0113	porphobilinogen synthase activity
O9K61_RS13100	COG1587	Uroporphyrinogen-III synthase
O9K61_RS13110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
O9K61_RS13130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
O9K61_RS13135	COG0470	DNA polymerase III
O9K61_RS13135	COG1067	ATP-dependent peptidase activity
O9K61_RS13150	COG0457	Tetratricopeptide repeat
O9K61_RS13150	COG1477	protein flavinylation
O9K61_RS13165	COG0473	3-isopropylmalate dehydrogenase activity
O9K61_RS13180	COG0440	acetolactate synthase activity
O9K61_RS13185	COG0028	Belongs to the TPP enzyme family
O9K61_RS13210	COG0622	Phosphoesterase
O9K61_RS13215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
O9K61_RS13225	COG5401	PFAM Sporulation and spore germination
O9K61_RS13235	COG1846	Transcriptional regulator
O9K61_RS13240	COG2197	response regulator
O9K61_RS13245	COG0824	Thioesterase
O9K61_RS13250	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
O9K61_RS13255	COG1053	succinate dehydrogenase
O9K61_RS13260	COG2009	succinate dehydrogenase
O9K61_RS13265	COG1719	4-vinyl reductase, 4VR
O9K61_RS13270	COG0527	aspartate kinase activity
O9K61_RS13280	COG3118	belongs to the thioredoxin family
O9K61_RS13285	COG3534	alpha-L-arabinofuranosidase
O9K61_RS13290	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
O9K61_RS13295	COG2086	electron transfer activity
O9K61_RS13300	COG1024	Enoyl-CoA hydratase
O9K61_RS13305	COG1309	transcriptional regulator
O9K61_RS13310	COG0318	PFAM AMP-dependent synthetase and ligase
O9K61_RS13320	COG3766	membrane
O9K61_RS13330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
O9K61_RS13330	COG1796	DNA polymerase
O9K61_RS13335	COG1286	toxin biosynthetic process
O9K61_RS13350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O9K61_RS13350	COG0072	phenylalanine-tRNA ligase activity
O9K61_RS13355	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
O9K61_RS13360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
O9K61_RS13370	COG3835	regulator
O9K61_RS13375	COG0277	FAD linked oxidase domain protein
O9K61_RS13380	COG0247	lactate metabolic process
O9K61_RS13385	COG1966	Carbon starvation protein
O9K61_RS13390	COG3534	alpha-L-arabinofuranosidase
O9K61_RS13395	COG0395	ABC-type sugar transport system, permease component
O9K61_RS13400	COG1175	transmembrane transport
O9K61_RS13405	COG1653	transport
O9K61_RS13415	COG0647	UMP catabolic process
O9K61_RS13420	COG0235	Class ii aldolase
O9K61_RS13425	COG1069	ribulokinase activity
O9K61_RS13430	COG2160	L-arabinose isomerase activity
O9K61_RS13435	COG3507	Belongs to the glycosyl hydrolase 43 family
O9K61_RS13440	COG1363	Peptidase, m42
O9K61_RS13450	COG3326	Membrane
O9K61_RS13455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
O9K61_RS13465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
O9K61_RS13470	COG1346	cytolysis
O9K61_RS13475	COG1380	Effector of murein hydrolase LrgA
O9K61_RS13480	COG3279	Response regulator of the LytR AlgR family
O9K61_RS13485	COG3275	phosphorelay sensor kinase activity
O9K61_RS13490	COG1011	Hydrolase
O9K61_RS13505	COG0398	Pfam SNARE associated Golgi protein
O9K61_RS13510	COG1484	DNA-dependent DNA replication
O9K61_RS13515	COG3611	Membrane attachment protein
O9K61_RS13530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
O9K61_RS13535	COG1733	regulation of RNA biosynthetic process
O9K61_RS13540	COG2814	Major facilitator Superfamily
O9K61_RS13545	COG0656	L-ascorbic acid biosynthetic process
O9K61_RS13550	COG0237	dephospho-CoA kinase activity
O9K61_RS13555	COG1971	Probably functions as a manganese efflux pump
O9K61_RS13560	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
O9K61_RS13565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
O9K61_RS13565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
O9K61_RS13570	COG5002	protein histidine kinase activity
O9K61_RS13575	COG0745	RESPONSE REGULATOR receiver
O9K61_RS13585	COG0538	isocitrate dehydrogenase activity
O9K61_RS13590	COG0372	Belongs to the citrate synthase family
O9K61_RS13610	COG0628	permease
O9K61_RS13615	COG3030	protein affecting phage T7 exclusion by the F plasmid
O9K61_RS13620	COG0469	pyruvate kinase activity
O9K61_RS13640	COG0281	malic enzyme
O9K61_RS13645	COG0587	DNA-directed DNA polymerase activity
O9K61_RS13665	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
O9K61_RS13675	COG4109	DRTGG domain
O9K61_RS13685	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS13705	COG0521	Mo-molybdopterin cofactor biosynthetic process
O9K61_RS13715	COG0827	DNA restriction-modification system
O9K61_RS13720	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
O9K61_RS13725	COG3874	Sporulation protein YtfJ
O9K61_RS13735	COG1714	RDD family
O9K61_RS13740	COG0616	signal peptide processing
O9K61_RS13745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
O9K61_RS13750	COG1574	metal-dependent hydrolase with the TIM-barrel fold
O9K61_RS13755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
O9K61_RS13770	COG1104	cysteine desulfurase activity
O9K61_RS13775	COG1114	Component of the transport system for branched-chain amino acids
O9K61_RS13785	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
O9K61_RS13790	COG1309	transcriptional regulator
O9K61_RS13795	COG1956	GAF domain-containing protein
O9K61_RS13800	COG2199	diguanylate cyclase activity
O9K61_RS13800	COG2203	Gaf domain
O9K61_RS13810	COG1012	belongs to the aldehyde dehydrogenase family
O9K61_RS13815	COG4282	regulation of fungal-type cell wall biogenesis
O9K61_RS13830	COG1017	nitric oxide dioxygenase activity
O9K61_RS13830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
O9K61_RS13840	COG0693	protein deglycase activity
O9K61_RS13860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
O9K61_RS13865	COG1378	Sugar-specific transcriptional regulator TrmB
O9K61_RS13890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
O9K61_RS13895	COG0454	-acetyltransferase
O9K61_RS13900	COG0517	IMP dehydrogenase activity
O9K61_RS13905	COG0123	including yeast histone deacetylase and acetoin utilization protein
O9K61_RS13915	COG1360	Flagellar Motor Protein
O9K61_RS13920	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
O9K61_RS13925	COG1609	Transcriptional regulator
O9K61_RS13930	COG1605	Chorismate mutase
O9K61_RS13930	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
O9K61_RS13935	COG3118	belongs to the thioredoxin family
O9K61_RS13940	COG4980	gas vesicle protein
O9K61_RS13945	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
O9K61_RS13955	COG1674	ftsk spoiiie
O9K61_RS13960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
O9K61_RS13970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O9K61_RS13980	COG1363	Peptidase, m42
O9K61_RS13985	COG5584	Small secreted protein
O9K61_RS13990	COG0281	malic enzyme
O9K61_RS13995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
O9K61_RS14010	COG0510	thiamine kinase activity
O9K61_RS14015	COG1597	lipid kinase activity
O9K61_RS14025	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
O9K61_RS14030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
O9K61_RS14035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O9K61_RS14040	COG2252	PERMEase
O9K61_RS14045	COG4473	ABC transporter
O9K61_RS14050	COG1131	(ABC) transporter
O9K61_RS14055	COG1349	DNA-binding transcription factor activity
O9K61_RS14060	COG1187	pseudouridine synthase activity
O9K61_RS14065	COG2244	polysaccharide biosynthetic process
O9K61_RS14070	COG2081	HI0933 family
O9K61_RS14075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
O9K61_RS14085	COG1609	Transcriptional regulator
O9K61_RS14090	COG1653	transport
O9K61_RS14095	COG1175	transmembrane transport
O9K61_RS14100	COG0395	ABC-type sugar transport system, permease component
O9K61_RS14105	COG1486	melibiose metabolic process
O9K61_RS14115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
O9K61_RS14130	COG2202	Pas domain
O9K61_RS14130	COG1366	Belongs to the anti-sigma-factor antagonist family
O9K61_RS14135	COG2814	Major facilitator Superfamily
O9K61_RS14140	COG5522	Integral membrane protein (intg_mem_TP0381)
O9K61_RS14145	COG0577	efflux transmembrane transporter activity
O9K61_RS14150	COG1136	(ABC) transporter
O9K61_RS14155	COG2205	protein histidine kinase activity
O9K61_RS14160	COG0745	RESPONSE REGULATOR receiver
O9K61_RS14165	COG0577	efflux transmembrane transporter activity
O9K61_RS14170	COG1136	(ABC) transporter
O9K61_RS14190	COG1131	(ABC) transporter
O9K61_RS14195	COG1725	Transcriptional regulator
O9K61_RS14215	COG0640	Transcriptional regulator
O9K61_RS14240	COG0477	Major facilitator Superfamily
O9K61_RS14245	COG1242	4 iron, 4 sulfur cluster binding
O9K61_RS14250	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
O9K61_RS14260	COG0584	glycerophosphoryl diester phosphodiesterase
O9K61_RS14270	COG2267	carboxylic ester hydrolase activity
O9K61_RS14275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
O9K61_RS14280	COG1113	amino acid transport
O9K61_RS14285	COG0367	asparagine synthase
O9K61_RS14305	COG1506	peptidase
O9K61_RS14310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
O9K61_RS14315	COG1116	anion transmembrane transporter activity
O9K61_RS14320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
O9K61_RS14325	COG0494	nUDIX hydrolase
O9K61_RS14330	COG4824	toxin secretion phage lysis holin
O9K61_RS14335	COG0783	Belongs to the Dps family
O9K61_RS14360	COG0288	reversible hydration of carbon dioxide
O9K61_RS14370	COG1271	oxidase subunit
O9K61_RS14375	COG1294	oxidase, subunit
O9K61_RS14385	COG4948	Mandelate Racemase Muconate Lactonizing
O9K61_RS14395	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
O9K61_RS14400	COG0596	Alpha beta hydrolase
O9K61_RS14410	COG1169	isochorismate synthase
O9K61_RS14415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
O9K61_RS14420	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
O9K61_RS14545	COG3859	Proton-coupled thiamine transporter YuaJ
O9K61_RS14550	COG2268	Band 7 protein
O9K61_RS14555	COG1585	Membrane protein implicated in regulation of membrane protease activity
O9K61_RS14560	COG2318	DinB family
O9K61_RS14570	COG1454	alcohol dehydrogenase
O9K61_RS14575	COG1012	belongs to the aldehyde dehydrogenase family
O9K61_RS14580	COG1510	regulation of RNA biosynthetic process
O9K61_RS14590	COG0569	domain protein
O9K61_RS14595	COG1705	Flagellar rod assembly protein muramidase FlgJ
O9K61_RS14600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
O9K61_RS14600	COG1017	nitric oxide dioxygenase activity
O9K61_RS14625	COG0628	permease
O9K61_RS14630	COG0673	inositol 2-dehydrogenase activity
O9K61_RS14635	COG0693	protein deglycase activity
O9K61_RS14640	COG0840	transmembrane signaling receptor activity
O9K61_RS14645	COG0840	transmembrane signaling receptor activity
O9K61_RS14650	COG0840	transmembrane signaling receptor activity
O9K61_RS14655	COG0840	transmembrane signaling receptor activity
O9K61_RS14670	COG2070	2-Nitropropane dioxygenase
O9K61_RS14675	COG0432	Pfam Uncharacterised protein family UPF0047
O9K61_RS14680	COG0366	Alpha amylase catalytic
O9K61_RS14685	COG1253	flavin adenine dinucleotide binding
O9K61_RS14690	COG2738	Putative neutral zinc metallopeptidase
O9K61_RS14705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
O9K61_RS14735	COG1979	alcohol dehydrogenase
O9K61_RS14740	COG1979	alcohol dehydrogenase
O9K61_RS14745	COG2155	Conserved Protein
O9K61_RS14750	COG1098	S1 RNA binding domain
O9K61_RS14755	COG0436	Aminotransferase
O9K61_RS14760	COG1522	sequence-specific DNA binding
O9K61_RS14765	COG2267	carboxylic ester hydrolase activity
O9K61_RS14775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
O9K61_RS14780	COG2205	protein histidine kinase activity
O9K61_RS14790	COG5018	Exonuclease
O9K61_RS14795	COG2814	Major facilitator Superfamily
O9K61_RS14800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O9K61_RS14805	COG3011	Protein conserved in bacteria
O9K61_RS14815	COG3290	protein histidine kinase activity
O9K61_RS14820	COG4565	transcriptional regulatory protein
O9K61_RS14825	COG1744	ABC transporter substrate-binding protein PnrA-like
O9K61_RS14830	COG3845	ABC transporter
O9K61_RS14835	COG4603	Belongs to the binding-protein-dependent transport system permease family
O9K61_RS14840	COG1079	Belongs to the binding-protein-dependent transport system permease family
O9K61_RS14850	COG2111	Na H antiporter
O9K61_RS14850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
O9K61_RS14855	COG2111	Na H antiporter
O9K61_RS14860	COG1006	Multisubunit Na H antiporter MnhC subunit
O9K61_RS14865	COG0651	ATP synthesis coupled electron transport
O9K61_RS14870	COG1863	multisubunit Na H antiporter MnhE subunit
O9K61_RS14875	COG2212	antiporter activity
O9K61_RS14880	COG1320	monovalent cation:proton antiporter activity
O9K61_RS14885	COG2050	protein possibly involved in aromatic compounds catabolism
O9K61_RS14890	COG2197	response regulator
O9K61_RS14895	COG4585	Histidine kinase
O9K61_RS14920	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
O9K61_RS14925	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
O9K61_RS14930	COG1335	isochorismatase
O9K61_RS14935	COG5506	Protein of unknown function (DUF1694)
O9K61_RS14950	COG0628	permease
O9K61_RS14960	COG1418	mRNA catabolic process
O9K61_RS14965	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS14975	COG1511	domain protein
O9K61_RS14980	COG1674	ftsk spoiiie
O9K61_RS14980	COG0433	COG0433 Predicted ATPase
O9K61_RS14985	COG4499	WXG100 protein secretion system (Wss), protein YukC
O9K61_RS14990	COG5417	Belongs to the EsaB family
O9K61_RS14995	COG4842	Belongs to the WXG100 family
O9K61_RS15000	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
O9K61_RS15000	COG2508	Transcriptional regulator
O9K61_RS15005	COG0686	Belongs to the AlaDH PNT family
O9K61_RS15010	COG5634	Uncharacterized conserved protein (DUF2278)
O9K61_RS15015	COG3251	PFAM MbtH domain protein
O9K61_RS15020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
O9K61_RS15025	COG3433	isochorismatase activity
O9K61_RS15025	COG1535	isochorismatase
O9K61_RS15030	COG1021	2,3-dihydroxybenzoate-AMP ligase
O9K61_RS15035	COG1169	isochorismate synthase
O9K61_RS15040	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS15045	COG2819	hydrolase of the alpha beta superfamily
O9K61_RS15050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
O9K61_RS15055	COG1268	BioY protein
O9K61_RS15060	COG2056	Na+-H+ antiporter family
O9K61_RS15070	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
O9K61_RS15075	COG3584	3D domain protein
O9K61_RS15090	COG1252	NADH dehydrogenase
O9K61_RS15120	COG1131	(ABC) transporter
O9K61_RS15140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
O9K61_RS15145	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
O9K61_RS15150	COG0316	Belongs to the HesB IscA family
O9K61_RS15160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O9K61_RS15170	COG1252	NADH dehydrogenase
O9K61_RS15175	COG4837	Protein of unknown function (DUF1462)
O9K61_RS15180	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
O9K61_RS15185	COG0823	Involved in the tonB-independent uptake of proteins
O9K61_RS15185	COG1506	peptidase
O9K61_RS15185	COG4946	Tricorn protease homolog
O9K61_RS15195	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
O9K61_RS15200	COG0460	homoserine dehydrogenase
O9K61_RS15205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
O9K61_RS15210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
O9K61_RS15215	COG0647	UMP catabolic process
O9K61_RS15220	COG2445	Protein of unknown function DUF86
O9K61_RS15225	COG4470	Protein conserved in bacteria
O9K61_RS15235	COG0739	heme binding
O9K61_RS15245	COG0737	Belongs to the 5'-nucleotidase family
O9K61_RS15250	COG0730	response to heat
O9K61_RS15255	COG1801	Protein of unknown function DUF72
O9K61_RS15270	COG2508	Transcriptional regulator
O9K61_RS15295	COG2814	Major facilitator Superfamily
O9K61_RS15300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
O9K61_RS15305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
O9K61_RS15310	COG2356	endonuclease I
O9K61_RS15315	COG3842	ATPase activity
O9K61_RS15320	COG2188	Transcriptional regulator
O9K61_RS15325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
O9K61_RS15330	COG0395	ABC-type sugar transport system, permease component
O9K61_RS15335	COG1175	transmembrane transport
O9K61_RS15340	COG1653	transport
O9K61_RS15345	COG2222	sugar isomerase
O9K61_RS15350	COG0789	Transcriptional regulator
O9K61_RS15380	COG0322	excinuclease ABC activity
O9K61_RS15385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
O9K61_RS15400	COG3409	Peptidoglycan-binding domain 1 protein
O9K61_RS15405	COG0719	Fe-S assembly protein
O9K61_RS15410	COG0822	iron-sulfur transferase activity
O9K61_RS15415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
O9K61_RS15420	COG0719	Fe-S assembly protein
O9K61_RS15425	COG0396	ATPase activity
O9K61_RS15435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
O9K61_RS15440	COG1464	Belongs to the NlpA lipoprotein family
O9K61_RS15445	COG2011	ABC-type metal ion transport system permease component
O9K61_RS15450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
O9K61_RS15460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
O9K61_RS15465	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
O9K61_RS15480	COG1393	Belongs to the ArsC family
O9K61_RS15485	COG1960	acyl-CoA dehydrogenase activity
O9K61_RS15490	COG0183	Belongs to the thiolase family
O9K61_RS15495	COG1024	Enoyl-CoA hydratase
O9K61_RS15495	COG1250	3-hydroxyacyl-CoA dehydrogenase
O9K61_RS15515	COG5577	PFAM Coat F domain
O9K61_RS15520	COG1846	Transcriptional regulator
O9K61_RS15525	COG0477	Major facilitator Superfamily
O9K61_RS15530	COG0583	DNA-binding transcription factor activity
O9K61_RS15550	COG1120	ATPase activity
O9K61_RS15565	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS15570	COG0783	Belongs to the Dps family
O9K61_RS15575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O9K61_RS15580	COG0745	RESPONSE REGULATOR receiver
O9K61_RS15585	COG2770	Histidine kinase
O9K61_RS15585	COG2205	protein histidine kinase activity
O9K61_RS15595	COG1309	transcriptional regulator
O9K61_RS15600	COG0114	fumarate hydratase activity
O9K61_RS15610	COG0697	spore germination
O9K61_RS15615	COG0814	amino acid
O9K61_RS15625	COG2197	response regulator
O9K61_RS15630	COG4585	Histidine kinase
O9K61_RS15635	COG4758	membrane
O9K61_RS15640	COG3595	metallopeptidase activity
O9K61_RS15645	COG1842	Phage shock protein A
O9K61_RS15650	COG4758	membrane
O9K61_RS15655	COG2814	Major facilitator Superfamily
O9K61_RS15660	COG2096	Adenosyltransferase
O9K61_RS15665	COG1120	ATPase activity
O9K61_RS15670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O9K61_RS15675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O9K61_RS15680	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS15685	COG3386	PFAM SMP-30 Gluconolaconase
O9K61_RS15690	COG2205	protein histidine kinase activity
O9K61_RS15695	COG0745	RESPONSE REGULATOR receiver
O9K61_RS15705	COG1191	sigma factor activity
O9K61_RS15715	COG2140	Oxalate decarboxylase
O9K61_RS15725	COG1120	ATPase activity
O9K61_RS15730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O9K61_RS15735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O9K61_RS15740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O9K61_RS15745	COG0531	amino acid
O9K61_RS15755	COG1988	membrane-bound metal-dependent
O9K61_RS15760	COG1368	sulfuric ester hydrolase activity
O9K61_RS15765	COG1910	domain protein
O9K61_RS15770	COG0725	ABC transporter, periplasmic molybdate-binding protein
O9K61_RS15775	COG4149	molybdate abc transporter
O9K61_RS15780	COG2197	response regulator
O9K61_RS15785	COG3850	Histidine kinase
O9K61_RS15790	COG1131	(ABC) transporter
O9K61_RS15800	COG0842	Transport permease protein
O9K61_RS15805	COG0656	L-ascorbic acid biosynthetic process
O9K61_RS15825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
O9K61_RS15830	COG3973	AAA domain
O9K61_RS15835	COG2860	membrane
O9K61_RS15845	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
O9K61_RS15850	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
O9K61_RS15855	COG2217	Heavy metal translocating P-type atpase
O9K61_RS15860	COG2217	Heavy metal translocating P-type atpase
O9K61_RS15865	COG2608	mercury ion transmembrane transporter activity
O9K61_RS15870	COG1937	Protein conserved in bacteria
O9K61_RS15875	COG0673	inositol 2-dehydrogenase activity
O9K61_RS15890	COG2814	Major facilitator Superfamily
O9K61_RS15905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O9K61_RS15910	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
O9K61_RS15915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O9K61_RS15920	COG1126	abc transporter atp-binding protein
O9K61_RS15925	COG0765	amino acid transport
O9K61_RS15930	COG0765	amino acid transport
O9K61_RS15935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O9K61_RS15940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
O9K61_RS15945	COG0454	-acetyltransferase
O9K61_RS15950	COG0583	DNA-binding transcription factor activity
O9K61_RS15955	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS15960	COG2732	(Barnase) inhibitor
O9K61_RS15970	COG2732	(Barnase) inhibitor
O9K61_RS15990	COG0557	exoribonuclease II activity
O9K61_RS15995	COG1647	Serine aminopeptidase, S33
O9K61_RS16000	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
O9K61_RS16005	COG1476	TRANSCRIPTIONal
O9K61_RS16010	COG1396	sequence-specific DNA binding
O9K61_RS16015	COG1396	sequence-specific DNA binding
O9K61_RS16020	COG1733	regulation of RNA biosynthetic process
O9K61_RS16045	COG1131	(ABC) transporter
O9K61_RS16050	COG1174	glycine betaine transport
O9K61_RS16055	COG1732	Glycine betaine
O9K61_RS16060	COG1174	glycine betaine transport
O9K61_RS16065	COG0517	IMP dehydrogenase activity
O9K61_RS16065	COG1125	glycine betaine transport
O9K61_RS16070	COG1510	regulation of RNA biosynthetic process
O9K61_RS16075	COG1174	glycine betaine transport
O9K61_RS16080	COG1732	Glycine betaine
O9K61_RS16085	COG1174	glycine betaine transport
O9K61_RS16090	COG0517	IMP dehydrogenase activity
O9K61_RS16090	COG1125	glycine betaine transport
O9K61_RS16095	COG1510	regulation of RNA biosynthetic process
O9K61_RS16100	COG2095	MarC family integral membrane protein
O9K61_RS16105	COG3064	Membrane
O9K61_RS16110	COG4640	response to antibiotic
O9K61_RS16115	COG0456	acetyltransferase
O9K61_RS16130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
O9K61_RS16150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
O9K61_RS16155	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
O9K61_RS16165	COG2234	aminopeptidase activity
O9K61_RS16185	COG0126	phosphoglycerate kinase activity
O9K61_RS16190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
O9K61_RS16195	COG2390	Transcriptional regulator
O9K61_RS16200	COG2814	Major facilitator Superfamily
O9K61_RS16205	COG1609	Transcriptional regulator
O9K61_RS16210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O9K61_RS16220	COG0583	DNA-binding transcription factor activity
O9K61_RS16225	COG0697	spore germination
O9K61_RS16230	COG1113	amino acid transport
O9K61_RS16245	COG1609	Transcriptional regulator
O9K61_RS16255	COG0561	phosphatase activity
O9K61_RS16260	COG1737	Transcriptional regulator
O9K61_RS16265	COG1070	Carbohydrate kinase
O9K61_RS16290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O9K61_RS16295	COG2186	Transcriptional regulator
O9K61_RS16300	COG1620	l-lactate permease
O9K61_RS16305	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
O9K61_RS16315	COG5039	Polysaccharide pyruvyl transferase
O9K61_RS16320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
O9K61_RS16325	COG0110	maltose O-acetyltransferase activity
O9K61_RS16330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
O9K61_RS16335	COG2244	polysaccharide biosynthetic process
O9K61_RS16340	COG1216	Glycosyl transferase, family 2
O9K61_RS16345	COG5039	Polysaccharide pyruvyl transferase
O9K61_RS16350	COG1216	Glycosyl transferase, family 2
O9K61_RS16360	COG0438	transferase activity, transferring glycosyl groups
O9K61_RS16365	COG1215	transferase activity, transferring glycosyl groups
O9K61_RS16370	COG0438	transferase activity, transferring glycosyl groups
O9K61_RS16375	COG1086	Polysaccharide biosynthesis protein
O9K61_RS16380	COG0489	protein tyrosine kinase activity
O9K61_RS16385	COG3944	biosynthesis protein
O9K61_RS16390	COG1396	sequence-specific DNA binding
O9K61_RS16395	COG2272	Belongs to the type-B carboxylesterase lipase family
O9K61_RS16405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
O9K61_RS16410	COG2364	Membrane
O9K61_RS16415	COG0456	acetyltransferase
O9K61_RS16420	COG3479	Phenolic acid decarboxylase
O9K61_RS16475	COG2223	nitrite transmembrane transporter activity
O9K61_RS16480	COG1609	Transcriptional regulator
O9K61_RS16490	COG0583	DNA-binding transcription factor activity
O9K61_RS16495	COG2828	Protein conserved in bacteria
O9K61_RS16500	COG0477	Major facilitator Superfamily
O9K61_RS16500	COG2814	Major facilitator Superfamily
O9K61_RS16505	COG1611	Belongs to the LOG family
O9K61_RS16510	COG1694	Mazg nucleotide pyrophosphohydrolase
O9K61_RS16515	COG0659	secondary active sulfate transmembrane transporter activity
O9K61_RS16520	COG0288	reversible hydration of carbon dioxide
O9K61_RS16525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
O9K61_RS16530	COG4290	ribonuclease
O9K61_RS16535	COG2162	N-hydroxyarylamine O-acetyltransferase activity
O9K61_RS16540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
O9K61_RS16550	COG0391	Required for morphogenesis under gluconeogenic growth conditions
O9K61_RS16560	COG1051	belongs to the nudix hydrolase family
O9K61_RS16565	COG0492	ferredoxin-NADP+ reductase activity
O9K61_RS16570	COG0791	NLP P60 protein
O9K61_RS16570	COG3883	PFAM NLP P60 protein
O9K61_RS16575	COG0457	Tetratricopeptide repeat
O9K61_RS16580	COG5002	protein histidine kinase activity
O9K61_RS16585	COG0745	RESPONSE REGULATOR receiver
O9K61_RS16590	COG1132	(ABC) transporter
O9K61_RS16595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
O9K61_RS16595	COG0140	phosphoribosyl-ATP diphosphatase activity
O9K61_RS16620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
O9K61_RS16635	COG4990	cell redox homeostasis
O9K61_RS16640	COG0110	maltose O-acetyltransferase activity
O9K61_RS16660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
O9K61_RS16670	COG2188	Transcriptional regulator
O9K61_RS16675	COG1309	transcriptional regulator
O9K61_RS16680	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
O9K61_RS16685	COG1950	PFAM Membrane protein of
O9K61_RS16690	COG1983	PspC domain protein
O9K61_RS16695	COG3595	metallopeptidase activity
O9K61_RS16710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
O9K61_RS16720	COG4897	Protein conserved in bacteria
O9K61_RS16725	COG3848	Pyruvate phosphate dikinase
O9K61_RS16725	COG0574	Belongs to the PEP-utilizing enzyme family
O9K61_RS16730	COG1309	transcriptional regulator
O9K61_RS16735	COG2814	Major facilitator Superfamily
O9K61_RS16750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O9K61_RS16760	COG0793	Belongs to the peptidase S41A family
O9K61_RS16760	COG3409	Peptidoglycan-binding domain 1 protein
O9K61_RS16765	COG3420	alginic acid biosynthetic process
O9K61_RS16770	COG2177	Part of the ABC transporter FtsEX involved in
O9K61_RS16775	COG2884	Cell division ATP-binding protein ftsE
O9K61_RS16780	COG2010	Cytochrome c
O9K61_RS16785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O9K61_RS16800	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
O9K61_RS16815	COG1516	flagellar protein fliS
O9K61_RS16820	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
O9K61_RS16825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
O9K61_RS16845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
O9K61_RS16850	COG1256	bacterial-type flagellum assembly
O9K61_RS16850	COG4786	Flagellar basal body rod
O9K61_RS16855	COG3418	PFAM FlgN family protein
O9K61_RS16860	COG2747	anti-sigma28 factor FlgM
O9K61_RS16870	COG1040	competence protein
O9K61_RS16880	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
O9K61_RS16885	COG1307	EDD domain protein, DegV family
O9K61_RS16890	COG2197	response regulator
O9K61_RS16895	COG4585	Histidine kinase
O9K61_RS16900	COG1739	Uncharacterized protein family UPF0029
O9K61_RS16905	COG1316	TRANSCRIPTIONal
O9K61_RS16910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
O9K61_RS16915	COG0438	transferase activity, transferring glycosyl groups
O9K61_RS16920	COG1215	transferase activity, transferring glycosyl groups
O9K61_RS16925	COG3206	protein involved in exopolysaccharide biosynthesis
O9K61_RS16930	COG3307	-O-antigen
O9K61_RS16935	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
O9K61_RS16940	COG0297	glycogen (starch) synthase activity
O9K61_RS16940	COG0438	transferase activity, transferring glycosyl groups
O9K61_RS16945	COG2244	polysaccharide biosynthetic process
O9K61_RS16955	COG0860	N-Acetylmuramoyl-L-alanine amidase
O9K61_RS16955	COG2247	cell wall binding repeat
O9K61_RS16960	COG2247	cell wall binding repeat
O9K61_RS16960	COG2385	sporulation resulting in formation of a cellular spore
O9K61_RS16970	COG1316	TRANSCRIPTIONal
O9K61_RS16980	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
O9K61_RS16985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
O9K61_RS16990	COG1134	teichoic acid transport
O9K61_RS16995	COG1682	transport, permease protein
O9K61_RS17000	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
O9K61_RS17010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
O9K61_RS17015	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
O9K61_RS17020	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
O9K61_RS17025	COG4193	domain, Protein
O9K61_RS17030	COG1482	cell wall glycoprotein biosynthetic process
O9K61_RS17035	COG0697	spore germination
O9K61_RS17040	COG0814	amino acid
O9K61_RS17050	COG1215	transferase activity, transferring glycosyl groups
O9K61_RS17055	COG2814	Major facilitator Superfamily
O9K61_RS17060	COG1316	TRANSCRIPTIONal
O9K61_RS17065	COG0561	phosphatase activity
O9K61_RS17070	COG2433	Pfam Transposase IS66
O9K61_RS17075	COG0791	NLP P60 protein
O9K61_RS17085	COG2843	Capsule synthesis protein
O9K61_RS17095	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
O9K61_RS17100	COG0697	spore germination
O9K61_RS17105	COG0814	amino acid
O9K61_RS17115	COG1609	Transcriptional regulator
O9K61_RS17120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
O9K61_RS17130	COG1129	ABC transporter
O9K61_RS17135	COG1172	Belongs to the binding-protein-dependent transport system permease family
O9K61_RS17140	COG1879	ABC-type sugar transport system periplasmic component
O9K61_RS17145	COG3103	Sh3 type 3 domain protein
O9K61_RS17150	COG2249	NAD(P)H dehydrogenase (quinone) activity
O9K61_RS17155	COG3527	Alpha-acetolactate decarboxylase
O9K61_RS17160	COG0028	Belongs to the TPP enzyme family
O9K61_RS17165	COG0583	DNA-binding transcription factor activity
O9K61_RS17170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
O9K61_RS17185	COG5337	Spore coat protein CotH
O9K61_RS17195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
O9K61_RS17205	COG0405	Gamma-glutamyltransferase
O9K61_RS17210	COG1522	sequence-specific DNA binding
O9K61_RS17215	COG2059	Chromate
O9K61_RS17220	COG2059	Chromate
O9K61_RS17270	COG5444	nuclease activity
O9K61_RS17285	COG3878	Protein conserved in bacteria
O9K61_RS17290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
O9K61_RS17295	COG4464	protein tyrosine phosphatase activity
O9K61_RS17300	COG0489	protein tyrosine kinase activity
O9K61_RS17305	COG3944	biosynthesis protein
O9K61_RS17315	COG4715	Zinc finger, swim domain protein
O9K61_RS17320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
O9K61_RS17325	COG0561	phosphatase activity
O9K61_RS17330	COG1349	DNA-binding transcription factor activity
O9K61_RS17335	COG0629	single-stranded DNA binding
O9K61_RS17360	COG0457	Tetratricopeptide repeat
O9K61_RS17365	COG4786	Flagellar basal body rod
O9K61_RS17370	COG4786	Flagellar basal body rod
O9K61_RS17375	COG1077	Cell shape determining protein MreB Mrl
O9K61_RS17380	COG1609	Transcriptional regulator
O9K61_RS17385	COG1846	Transcriptional regulator
O9K61_RS17390	COG2814	Major facilitator Superfamily
O9K61_RS17395	COG1953	Uracil, thiamine, allantoin
O9K61_RS17400	COG0477	Major facilitator Superfamily
O9K61_RS17405	COG1335	isochorismatase
O9K61_RS17410	COG0004	ammonium transporteR
O9K61_RS17415	COG0347	Belongs to the P(II) protein family
O9K61_RS17420	COG0772	Belongs to the SEDS family
O9K61_RS17425	COG0671	phosphoesterase, PA-phosphatase related
O9K61_RS17435	COG0739	heme binding
O9K61_RS17440	COG1247	-acetyltransferase
O9K61_RS17455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O9K61_RS17465	COG0726	polysaccharide deacetylase
O9K61_RS17470	COG1959	2 iron, 2 sulfur cluster binding
O9K61_RS17485	COG0831	urea catabolic process
O9K61_RS17490	COG3237	CsbD-like
O9K61_RS17495	COG1994	Peptidase M50
O9K61_RS17500	COG0457	Tetratricopeptide repeat
O9K61_RS17510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
O9K61_RS17520	COG2304	oxidoreductase activity
O9K61_RS17525	COG2304	oxidoreductase activity
O9K61_RS17530	COG2385	sporulation resulting in formation of a cellular spore
O9K61_RS17535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
O9K61_RS17545	COG4836	Membrane
O9K61_RS17615	COG0698	ribose 5-phosphate isomerase
O9K61_RS17620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
O9K61_RS17630	COG0009	L-threonylcarbamoyladenylate synthase
O9K61_RS17635	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
O9K61_RS17655	COG2890	protein-(glutamine-N5) methyltransferase activity
O9K61_RS17660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
O9K61_RS17665	COG0346	lactoylglutathione lyase activity
O9K61_RS17670	COG0789	Transcriptional regulator
O9K61_RS17675	COG0679	Auxin Efflux Carrier
O9K61_RS17680	COG0281	malic enzyme
O9K61_RS17695	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
O9K61_RS17705	COG1494	fructose-1,6-bisphosphatase
O9K61_RS17710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
O9K61_RS17720	COG0191	fructose-bisphosphate aldolase activity
O9K61_RS17725	COG2204	response regulator
O9K61_RS17730	COG4821	SIS domain
O9K61_RS17745	COG0247	lactate metabolic process
O9K61_RS17745	COG2181	nitrate reductase activity
O9K61_RS17750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O9K61_RS17765	COG1132	(ABC) transporter
O9K61_RS17770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
O9K61_RS17780	COG2181	nitrate reductase activity
O9K61_RS17785	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
O9K61_RS17790	COG1140	nitrate reductase beta subunit
O9K61_RS17795	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
O9K61_RS17800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
O9K61_RS17810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
O9K61_RS17815	COG2223	nitrite transmembrane transporter activity
O9K61_RS17825	COG4506	Protein conserved in bacteria
O9K61_RS17835	COG3391	amine dehydrogenase activity
O9K61_RS17840	COG3391	amine dehydrogenase activity
O9K61_RS17845	COG0457	Tetratricopeptide repeat
O9K61_RS17885	COG0010	Belongs to the arginase family
O9K61_RS17890	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
O9K61_RS17895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
O9K61_RS17910	COG1994	Peptidase M50
O9K61_RS17915	COG1942	4-Oxalocrotonate Tautomerase
O9K61_RS17920	COG1846	Transcriptional regulator
O9K61_RS17925	COG0531	amino acid
O9K61_RS17930	COG3465	dGTPase activity
O9K61_RS17935	COG1078	dGTPase activity
O9K61_RS17950	COG1695	Transcriptional regulator
O9K61_RS17960	COG1131	(ABC) transporter
O9K61_RS17965	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
O9K61_RS17995	COG0583	DNA-binding transcription factor activity
O9K61_RS18000	COG2855	membrane
O9K61_RS18005	COG0280	phosphate acetyltransferase
O9K61_RS18015	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS18020	COG0436	Aminotransferase
O9K61_RS18050	COG2814	Major facilitator Superfamily
O9K61_RS18055	COG2814	Major facilitator Superfamily
O9K61_RS18060	COG0833	amino acid
O9K61_RS18065	COG4187	Peptidase family M20/M25/M40
O9K61_RS18070	COG1012	belongs to the aldehyde dehydrogenase family
O9K61_RS18075	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
O9K61_RS18085	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
O9K61_RS18090	COG1091	dTDP-4-dehydrorhamnose reductase activity
O9K61_RS18095	COG1088	dTDP-glucose 4,6-dehydratase activity
O9K61_RS18100	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
O9K61_RS18105	COG3980	spore coat polysaccharide biosynthesis protein
O9K61_RS18110	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
O9K61_RS18115	COG2089	acid synthase
O9K61_RS18120	COG0456	acetyltransferase
O9K61_RS18125	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
O9K61_RS18130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
O9K61_RS18135	COG0463	Glycosyl transferase, family 2
O9K61_RS18145	COG2363	Small membrane protein
O9K61_RS18150	COG2233	PERMEase
O9K61_RS18165	COG1216	Glycosyl transferase, family 2
O9K61_RS18180	COG1695	Transcriptional regulator
O9K61_RS18185	COG0351	phosphomethylpyrimidine kinase
O9K61_RS18195	COG1621	beta-fructofuranosidase activity
O9K61_RS18200	COG1263	PTS System
O9K61_RS18200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O9K61_RS18205	COG3711	transcriptional antiterminator
O9K61_RS18215	COG1404	Belongs to the peptidase S8 family
O9K61_RS18220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
O9K61_RS18230	COG0778	Nitroreductase
O9K61_RS18235	COG0772	Belongs to the SEDS family
O9K61_RS18240	COG0454	-acetyltransferase
O9K61_RS18260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
O9K61_RS18265	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
O9K61_RS18270	COG2261	transglycosylase associated protein
O9K61_RS18275	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
O9K61_RS18280	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
O9K61_RS18285	COG2246	polysaccharide biosynthetic process
O9K61_RS18290	COG1309	transcriptional regulator
O9K61_RS18310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
O9K61_RS18315	COG2837	iron assimilation
O9K61_RS18335	COG0583	DNA-binding transcription factor activity
O9K61_RS18345	COG1346	cytolysis
O9K61_RS18350	COG4895	conserved protein (DUF2196)
O9K61_RS18360	COG0789	Transcriptional regulator
O9K61_RS18365	COG5504	Zn-dependent protease
O9K61_RS18370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
O9K61_RS18375	COG0346	lactoylglutathione lyase activity
O9K61_RS18380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O9K61_RS18385	COG1404	Belongs to the peptidase S8 family
O9K61_RS18390	COG1442	glycosyl transferase family 8
O9K61_RS18395	COG2357	RelA SpoT domain protein
O9K61_RS18400	COG1575	Belongs to the MenA family. Type 1 subfamily
O9K61_RS18415	COG1696	Membrane protein involved in D-alanine export
O9K61_RS18425	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
O9K61_RS18430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
O9K61_RS18435	COG1486	melibiose metabolic process
O9K61_RS18440	COG1447	Phosphotransferase system cellobiose-specific component IIA
O9K61_RS18445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O9K61_RS18450	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O9K61_RS18455	COG3711	transcriptional antiterminator
O9K61_RS18455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
O9K61_RS18470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O9K61_RS18475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
O9K61_RS18485	COG0640	Transcriptional regulator
O9K61_RS18490	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
O9K61_RS18495	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O9K61_RS18500	COG1447	Phosphotransferase system cellobiose-specific component IIA
O9K61_RS18505	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
O9K61_RS18510	COG2723	6-phospho-beta-galactosidase activity
O9K61_RS18515	COG1940	carbohydrate kinase activity
O9K61_RS18520	COG1482	cell wall glycoprotein biosynthetic process
O9K61_RS18530	COG0753	catalase activity
O9K61_RS18535	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
O9K61_RS18540	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
O9K61_RS18545	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
O9K61_RS18550	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
O9K61_RS18555	COG4988	ABC transporter
O9K61_RS18560	COG1294	oxidase, subunit
O9K61_RS18565	COG1271	oxidase subunit
O9K61_RS18570	COG3493	citrate carrier protein
O9K61_RS18575	COG0726	polysaccharide deacetylase
O9K61_RS18580	COG3842	ATPase activity
O9K61_RS18585	COG2508	Transcriptional regulator
O9K61_RS18590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O9K61_RS18600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
O9K61_RS18615	COG4894	glucomannan catabolic process
O9K61_RS18620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
O9K61_RS18625	COG0500	methyltransferase
O9K61_RS18630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O9K61_RS18645	COG0753	catalase activity
O9K61_RS18645	COG0693	protein deglycase activity
O9K61_RS18650	COG2851	Citrate transporter
O9K61_RS18655	COG2273	Hydrolase Family 16
O9K61_RS18660	COG3711	transcriptional antiterminator
O9K61_RS18665	COG2270	Major facilitator Superfamily
O9K61_RS18670	COG0513	Belongs to the DEAD box helicase family
O9K61_RS18715	COG3209	COG3209 Rhs family protein
O9K61_RS18725	COG0697	spore germination
O9K61_RS18730	COG0589	response to stress
O9K61_RS18735	COG2723	6-phospho-beta-galactosidase activity
O9K61_RS18740	COG2190	(PTS) system
O9K61_RS18740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
O9K61_RS18740	COG1263	PTS System
O9K61_RS18750	COG0494	nUDIX hydrolase
O9K61_RS18755	COG3507	Belongs to the glycosyl hydrolase 43 family
O9K61_RS18780	COG0010	Belongs to the arginase family
O9K61_RS18785	COG0833	amino acid
O9K61_RS18790	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
O9K61_RS18795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
O9K61_RS18805	COG2390	Transcriptional regulator
O9K61_RS18810	COG0561	phosphatase activity
O9K61_RS18840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
O9K61_RS18845	COG5294	Protein conserved in bacteria
O9K61_RS18850	COG0577	efflux transmembrane transporter activity
O9K61_RS18855	COG1136	(ABC) transporter
O9K61_RS18860	COG2205	protein histidine kinase activity
O9K61_RS18865	COG0745	RESPONSE REGULATOR receiver
O9K61_RS18880	COG1082	Xylose isomerase domain protein TIM barrel
O9K61_RS18890	COG2814	Major facilitator Superfamily
O9K61_RS18920	COG1349	DNA-binding transcription factor activity
O9K61_RS18925	COG0667	Aldo Keto reductase
O9K61_RS18935	COG2814	Major facilitator Superfamily
O9K61_RS18950	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS18955	COG2197	response regulator
O9K61_RS18960	COG4585	Histidine kinase
O9K61_RS18965	COG3239	Fatty acid desaturase
O9K61_RS18970	COG1309	transcriptional regulator
O9K61_RS18975	COG1012	belongs to the aldehyde dehydrogenase family
O9K61_RS18980	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
O9K61_RS18990	COG0640	Transcriptional regulator
O9K61_RS18995	COG2814	Major facilitator Superfamily
O9K61_RS19000	COG1714	RDD family
O9K61_RS19010	COG0450	alkyl hydroperoxide reductase
O9K61_RS19015	COG3634	alkyl hydroperoxide reductase activity
O9K61_RS19020	COG3177	Filamentation induced by cAMP protein fic
O9K61_RS19025	COG1113	amino acid transport
O9K61_RS19050	COG2068	MobA-Related Protein
O9K61_RS19055	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
O9K61_RS19090	COG0210	DNA helicase
O9K61_RS19140	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
O9K61_RS19145	COG0667	Aldo Keto reductase
O9K61_RS19150	COG0456	acetyltransferase
O9K61_RS19160	COG0457	Tetratricopeptide repeat
O9K61_RS19165	COG0010	Belongs to the arginase family
O9K61_RS19170	COG0833	amino acid
O9K61_RS19175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
O9K61_RS19180	COG5658	integral membrane protein
O9K61_RS19185	COG0640	Transcriptional regulator
O9K61_RS19190	COG3829	transcription factor binding
O9K61_RS19200	COG0488	(ABC) transporter
O9K61_RS19215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
O9K61_RS19220	COG3850	Histidine kinase
O9K61_RS19220	COG5002	protein histidine kinase activity
O9K61_RS19225	COG0745	RESPONSE REGULATOR receiver
O9K61_RS19230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
O9K61_RS19235	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
O9K61_RS19240	COG4853	Protein conserved in bacteria
O9K61_RS19245	COG4863	YycH protein
O9K61_RS19250	COG5002	protein histidine kinase activity
O9K61_RS19255	COG0745	RESPONSE REGULATOR receiver
O9K61_RS19285	COG0346	lactoylglutathione lyase activity
O9K61_RS19290	COG0305	Participates in initiation and elongation during chromosome replication
O9K61_RS19305	COG3093	addiction module antidote protein HigA
O9K61_RS19310	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
O9K61_RS19325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
O9K61_RS19330	COG0438	transferase activity, transferring glycosyl groups
O9K61_RS19350	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
O9K61_RS19355	COG4241	membrane
O9K61_RS19365	COG5577	PFAM Coat F domain
O9K61_RS19370	COG1733	regulation of RNA biosynthetic process
O9K61_RS19385	COG0697	spore germination
O9K61_RS19390	COG1621	beta-fructofuranosidase activity
O9K61_RS19395	COG1621	beta-fructofuranosidase activity
O9K61_RS19400	COG1802	Transcriptional regulator
O9K61_RS19405	COG2318	DinB family
O9K61_RS19410	COG2211	Major facilitator Superfamily
O9K61_RS19415	COG0583	DNA-binding transcription factor activity
O9K61_RS19430	COG0778	Nitroreductase
O9K61_RS19435	COG1846	Transcriptional regulator
O9K61_RS19440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
O9K61_RS19445	COG1846	Transcriptional regulator
O9K61_RS19450	COG2153	protein acetylation
O9K61_RS19460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
O9K61_RS19465	COG0583	DNA-binding transcription factor activity
O9K61_RS19470	COG1028	Short-chain dehydrogenase reductase Sdr
O9K61_RS19475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
O9K61_RS19480	COG0697	spore germination
O9K61_RS19495	COG1078	dGTPase activity
O9K61_RS19510	COG1331	Highly conserved protein containing a thioredoxin domain
O9K61_RS19515	COG1266	CAAX protease self-immunity
O9K61_RS19520	COG0477	Major facilitator Superfamily
O9K61_RS19520	COG2814	Major facilitator Superfamily
O9K61_RS19525	COG0346	lactoylglutathione lyase activity
O9K61_RS19530	COG1609	Transcriptional regulator
O9K61_RS19535	COG0708	Exodeoxyribonuclease III
O9K61_RS19540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
O9K61_RS19545	COG2169	Transcriptional regulator
O9K61_RS19555	COG0629	single-stranded DNA binding
O9K61_RS19565	COG0012	GTP binding
O9K61_RS19570	COG0243	molybdopterin cofactor binding
O9K61_RS19575	COG4481	Protein conserved in bacteria
O9K61_RS19580	COG3949	Membrane
O9K61_RS19595	COG1475	DNA binding
O9K61_RS19600	COG1192	Involved in chromosome partitioning
O9K61_RS19625	COG1847	R3H domain protein
O9K61_RS19630	COG0706	membrane insertase activity