locus-tag	class	description
MG974_RS00010	COG0592	DNA-directed DNA polymerase activity
MG974_RS00015	COG2501	S4 domain
MG974_RS00030	COG0187	DNA topoisomerase II activity
MG974_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MG974_RS00070	COG0516	GMP reductase activity
MG974_RS00070	COG0517	IMP dehydrogenase activity
MG974_RS00075	COG1686	Belongs to the peptidase S11 family
MG974_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
MG974_RS00105	COG1428	Deoxynucleoside kinase
MG974_RS00110	COG1428	Deoxynucleoside kinase
MG974_RS00115	COG1388	LysM domain
MG974_RS00115	COG3858	chitin binding
MG974_RS00120	COG1335	isochorismatase
MG974_RS00125	COG0590	tRNA wobble adenosine to inosine editing
MG974_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MG974_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MG974_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MG974_RS00195	COG3853	Toxic anion resistance protein (TelA)
MG974_RS00200	COG1982	Orn Lys Arg decarboxylase major
MG974_RS00210	COG3870	Protein conserved in bacteria
MG974_RS00215	COG1728	Protein conserved in bacteria
MG974_RS00220	COG0470	DNA polymerase III
MG974_RS00225	COG1774	PSP1 C-terminal conserved region
MG974_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MG974_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MG974_RS00250	COG2002	toxin-antitoxin pair type II binding
MG974_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MG974_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MG974_RS00260	COG0084	hydrolase, TatD family'
MG974_RS00265	COG3584	3D domain protein
MG974_RS00265	COG3583	domain protein
MG974_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MG974_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MG974_RS00285	COG4466	Protein conserved in bacteria
MG974_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MG974_RS00305	COG0251	oxidation-reduction process
MG974_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MG974_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MG974_RS00345	COG2002	toxin-antitoxin pair type II binding
MG974_RS00350	COG2244	polysaccharide biosynthetic process
MG974_RS00355	COG3956	TIGRFAM MazG family protein
MG974_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MG974_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MG974_RS00380	COG1098	S1 RNA binding domain
MG974_RS00395	COG2208	phosphoserine phosphatase activity
MG974_RS00400	COG2304	oxidoreductase activity
MG974_RS00405	COG0515	serine threonine protein kinase
MG974_RS00410	COG0037	tRNA processing
MG974_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MG974_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MG974_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MG974_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MG974_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MG974_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
MG974_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MG974_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MG974_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MG974_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MG974_RS00475	COG1396	sequence-specific DNA binding
MG974_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MG974_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MG974_RS00565	COG4463	regulation of RNA biosynthetic process
MG974_RS00570	COG3880	PFAM UvrB UvrC protein
MG974_RS00580	COG0542	response to heat
MG974_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MG974_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MG974_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
MG974_RS00615	COG1045	serine acetyltransferase
MG974_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MG974_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MG974_RS00635	COG3688	RNA-binding protein containing a PIN domain
MG974_RS00640	COG1595	DNA-templated transcription, initiation
MG974_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MG974_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
MG974_RS00680	COG2813	Specifically methylates the guanine in position
MG974_RS00695	COG1358	cellular component organization or biogenesis
MG974_RS00720	COG0596	Alpha beta hydrolase
MG974_RS00830	COG0201	protein transport
MG974_RS00840	COG0024	Methionine aminopeptidase
MG974_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MG974_RS00880	COG1122	ATPase activity
MG974_RS00885	COG1122	ATPase activity
MG974_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MG974_RS00910	COG2226	methyltransferase
MG974_RS00915	COG2318	DinB family
MG974_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
MG974_RS00930	COG0489	protein tyrosine kinase activity
MG974_RS00940	COG2194	sulfuric ester hydrolase activity
MG974_RS00945	COG0726	polysaccharide deacetylase
MG974_RS01005	COG0738	Major facilitator superfamily
MG974_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MG974_RS01020	COG1063	alcohol dehydrogenase
MG974_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
MG974_RS01030	COG0385	Bile acid
MG974_RS01035	COG2819	hydrolase of the alpha beta superfamily
MG974_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MG974_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MG974_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MG974_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MG974_RS01055	COG2207	Transcriptional regulator
MG974_RS01060	COG3876	Protein conserved in bacteria
MG974_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
MG974_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MG974_RS01075	COG1263	PTS System
MG974_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MG974_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MG974_RS01090	COG1683	Conserved Protein
MG974_RS01120	COG1595	DNA-templated transcription, initiation
MG974_RS01125	COG5662	AntiSigma factor
MG974_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MG974_RS01135	COG4856	YbbR-like protein
MG974_RS01175	COG1346	cytolysis
MG974_RS01180	COG1380	Effector of murein hydrolase LrgA
MG974_RS01185	COG1846	Transcriptional regulator
MG974_RS01190	COG1113	amino acid transport
MG974_RS01195	COG1011	Hydrolase
MG974_RS01200	COG4585	Histidine kinase
MG974_RS01205	COG2197	response regulator
MG974_RS01210	COG1131	(ABC) transporter
MG974_RS01250	COG0531	amino acid
MG974_RS01255	COG0584	glycerophosphoryl diester phosphodiesterase
MG974_RS01260	COG2271	Major facilitator Superfamily
MG974_RS01270	COG2368	4-hydroxyphenylacetate
MG974_RS01280	COG3409	Peptidoglycan-binding domain 1 protein
MG974_RS01295	COG0371	Dehydrogenase
MG974_RS01305	COG1183	phosphatidylcholine synthase activity
MG974_RS01310	COG0586	Pfam SNARE associated Golgi protein
MG974_RS01315	COG0688	phosphatidylethanolamine metabolic process
MG974_RS01330	COG1301	dicarboxylic acid transport
MG974_RS01335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MG974_RS01340	COG0833	amino acid
MG974_RS01345	COG2040	homocysteine
MG974_RS01350	COG1115	amino acid carrier protein
MG974_RS01355	COG2066	Belongs to the glutaminase family
MG974_RS01360	COG4191	Histidine kinase
MG974_RS01365	COG0784	Response regulator, receiver
MG974_RS01370	COG3173	Aminoglycoside phosphotransferase
MG974_RS01380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MG974_RS01385	COG0778	Nitroreductase
MG974_RS01390	COG0346	lactoylglutathione lyase activity
MG974_RS01395	COG2259	Doxx family
MG974_RS01400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG974_RS01415	COG3773	Cell wall hydrolase
MG974_RS01420	COG3540	Alkaline phosphatase
MG974_RS01425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MG974_RS01430	COG0805	protein transport
MG974_RS01440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MG974_RS01445	COG0477	Major facilitator Superfamily
MG974_RS01450	COG1309	transcriptional regulator
MG974_RS01455	COG0252	asparaginase activity
MG974_RS01460	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MG974_RS01465	COG3012	SEC-C Motif Domain Protein
MG974_RS01465	COG1405	negative regulation of cell septum assembly
MG974_RS01470	COG0667	Aldo Keto reductase
MG974_RS01480	COG1595	DNA-templated transcription, initiation
MG974_RS01485	COG1595	DNA-templated transcription, initiation
MG974_RS01490	COG1876	peptidase activity
MG974_RS01495	COG0457	Tetratricopeptide repeat
MG974_RS01500	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS01505	COG0366	Alpha amylase catalytic
MG974_RS01510	COG0803	Belongs to the bacterial solute-binding protein 9 family
MG974_RS01515	COG1121	(ABC) transporter
MG974_RS01520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MG974_RS01525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MG974_RS01530	COG2310	stress, protein
MG974_RS01535	COG2310	stress, protein
MG974_RS01540	COG2310	stress, protein
MG974_RS01545	COG0861	Integral membrane protein TerC family
MG974_RS01555	COG3853	Toxic anion resistance protein (TelA)
MG974_RS01560	COG0477	Major facilitator Superfamily
MG974_RS01565	COG0517	IMP dehydrogenase activity
MG974_RS01565	COG4175	Glycine betaine
MG974_RS01570	COG4176	ABC-type proline glycine betaine transport system permease component
MG974_RS01575	COG2113	Glycine betaine
MG974_RS01580	COG1473	amidohydrolase
MG974_RS01585	COG1288	antiporter activity
MG974_RS01595	COG0366	Alpha amylase catalytic
MG974_RS01605	COG2814	Major facilitator Superfamily
MG974_RS01610	COG1846	Transcriptional regulator
MG974_RS01615	COG1280	lysine exporter protein (LysE YggA)
MG974_RS01620	COG3403	YqcI/YcgG family
MG974_RS01625	COG1113	amino acid transport
MG974_RS01630	COG3665	Urea carboxylase-associated protein
MG974_RS01645	COG1660	Displays ATPase and GTPase activities
MG974_RS01655	COG2271	Major facilitator Superfamily
MG974_RS01660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MG974_RS01665	COG3458	cephalosporin-C deacetylase activity
MG974_RS01670	COG3541	Predicted nucleotidyltransferase
MG974_RS01675	COG0506	proline dehydrogenase activity
MG974_RS01680	COG1012	belongs to the aldehyde dehydrogenase family
MG974_RS01685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MG974_RS01690	COG2508	Transcriptional regulator
MG974_RS01700	COG1587	Uroporphyrinogen-III synthase
MG974_RS01700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MG974_RS01705	COG2146	nitrite reductase [NAD(P)H] activity
MG974_RS01710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MG974_RS01720	COG0523	cobalamin synthesis protein
MG974_RS01725	COG1063	alcohol dehydrogenase
MG974_RS01730	COG1714	RDD family
MG974_RS01755	COG3209	COG3209 Rhs family protein
MG974_RS01760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MG974_RS01765	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MG974_RS01770	COG1733	regulation of RNA biosynthetic process
MG974_RS01775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS01795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS01805	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MG974_RS01820	COG2364	Membrane
MG974_RS01825	COG1126	abc transporter atp-binding protein
MG974_RS01830	COG0765	amino acid transport
MG974_RS01835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MG974_RS01840	COG0583	DNA-binding transcription factor activity
MG974_RS01845	COG0163	prenyltransferase activity
MG974_RS01850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MG974_RS01865	COG3104	oligopeptide transport
MG974_RS01870	COG5434	Belongs to the glycosyl hydrolase 28 family
MG974_RS01880	COG0697	spore germination
MG974_RS01890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MG974_RS01895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MG974_RS01900	COG0456	acetyltransferase
MG974_RS01905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MG974_RS01910	COG0765	amino acid transport
MG974_RS01915	COG1126	abc transporter atp-binding protein
MG974_RS01920	COG1473	amidohydrolase
MG974_RS01925	COG2079	MmgE PrpD family protein
MG974_RS01930	COG1136	(ABC) transporter
MG974_RS01935	COG0577	efflux transmembrane transporter activity
MG974_RS01940	COG0745	RESPONSE REGULATOR receiver
MG974_RS01945	COG5002	protein histidine kinase activity
MG974_RS01945	COG3850	Histidine kinase
MG974_RS01950	COG0457	Tetratricopeptide repeat
MG974_RS01965	COG0527	aspartate kinase activity
MG974_RS01970	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MG974_RS01975	COG4605	iron ion homeostasis
MG974_RS01980	COG4604	ABC transporter, ATP-binding protein
MG974_RS01985	COG4607	ABC-type enterochelin transport system periplasmic component
MG974_RS01990	COG2814	Major facilitator Superfamily
MG974_RS01995	COG1309	transcriptional regulator
MG974_RS02000	COG0778	Nitroreductase
MG974_RS02005	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MG974_RS02010	COG0640	Transcriptional regulator
MG974_RS02015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MG974_RS02020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MG974_RS02025	COG1012	belongs to the aldehyde dehydrogenase family
MG974_RS02030	COG4975	Glucose uptake
MG974_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS02040	COG4549	nuclear export factor GLE1
MG974_RS02045	COG1276	copper resistance
MG974_RS02045	COG2372	response to copper ion
MG974_RS02050	COG1349	DNA-binding transcription factor activity
MG974_RS02060	COG2213	PTS system mannitol-specific
MG974_RS02065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MG974_RS02075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MG974_RS02085	COG0561	phosphatase activity
MG974_RS02095	COG1914	H( )-stimulated, divalent metal cation uptake system
MG974_RS02105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MG974_RS02110	COG1984	allophanate hydrolase subunit 2
MG974_RS02115	COG1414	Transcriptional regulator
MG974_RS02120	COG2755	lipolytic protein G-D-S-L family
MG974_RS02130	COG2329	Antibiotic biosynthesis monooxygenase
MG974_RS02135	COG0768	penicillin binding
MG974_RS02140	COG4989	oxidoreductase activity
MG974_RS02145	COG3711	transcriptional antiterminator
MG974_RS02150	COG0318	PFAM AMP-dependent synthetase and ligase
MG974_RS02155	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS02160	COG1917	Cupin 2, conserved barrel domain protein
MG974_RS02165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MG974_RS02170	COG3871	stress protein (general stress protein 26)
MG974_RS02180	COG2814	Major facilitator Superfamily
MG974_RS02185	COG1522	sequence-specific DNA binding
MG974_RS02190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MG974_RS02190	COG0551	DNA topoisomerase type I activity
MG974_RS02195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MG974_RS02200	COG3706	GGDEF domain
MG974_RS02205	COG5298	Protein conserved in bacteria
MG974_RS02210	COG1215	transferase activity, transferring glycosyl groups
MG974_RS02220	COG0531	amino acid
MG974_RS02225	COG0494	nUDIX hydrolase
MG974_RS02230	COG0028	Belongs to the TPP enzyme family
MG974_RS02285	COG0457	Tetratricopeptide repeat
MG974_RS02310	COG1914	H( )-stimulated, divalent metal cation uptake system
MG974_RS02330	COG2076	Multidrug Resistance protein
MG974_RS02335	COG2217	Heavy metal translocating P-type atpase
MG974_RS02340	COG3729	General stress protein
MG974_RS02345	COG0662	Cupin 2, conserved barrel domain protein
MG974_RS02350	COG2329	Antibiotic biosynthesis monooxygenase
MG974_RS02355	COG3546	catalase activity
MG974_RS02360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MG974_RS02365	COG3290	protein histidine kinase activity
MG974_RS02370	COG4565	transcriptional regulatory protein
MG974_RS02375	COG1301	dicarboxylic acid transport
MG974_RS02380	COG0628	permease
MG974_RS02385	COG1131	(ABC) transporter
MG974_RS02390	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MG974_RS02400	COG1960	acyl-CoA dehydrogenase activity
MG974_RS02415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MG974_RS02420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG974_RS02430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MG974_RS02435	COG0513	Belongs to the DEAD box helicase family
MG974_RS02440	COG3402	PFAM membrane-flanked domain
MG974_RS02445	COG3428	Bacterial PH domain
MG974_RS02450	COG0705	Rhomboid family
MG974_RS02460	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MG974_RS02465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MG974_RS02470	COG0864	Transcriptional regulator
MG974_RS02475	COG2337	Toxic component of a toxin-antitoxin (TA) module
MG974_RS02480	COG1366	Belongs to the anti-sigma-factor antagonist family
MG974_RS02485	COG1366	Belongs to the anti-sigma-factor antagonist family
MG974_RS02490	COG2172	sigma factor antagonist activity
MG974_RS02495	COG2208	phosphoserine phosphatase activity
MG974_RS02500	COG1366	Belongs to the anti-sigma-factor antagonist family
MG974_RS02510	COG1191	sigma factor activity
MG974_RS02515	COG2208	phosphoserine phosphatase activity
MG974_RS02520	COG2183	response to ionizing radiation
MG974_RS02575	COG2249	NAD(P)H dehydrogenase (quinone) activity
MG974_RS02595	COG0477	Major facilitator Superfamily
MG974_RS02605	COG1764	response to oxidative stress
MG974_RS02610	COG1846	Transcriptional regulator
MG974_RS02620	COG1959	2 iron, 2 sulfur cluster binding
MG974_RS02625	COG2910	NAD(P)H-binding
MG974_RS02630	COG1278	Cold shock
MG974_RS02640	COG1937	Protein conserved in bacteria
MG974_RS02645	COG2210	Belongs to the sulfur carrier protein TusA family
MG974_RS02655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MG974_RS02655	COG0425	Belongs to the sulfur carrier protein TusA family
MG974_RS02665	COG0425	Belongs to the sulfur carrier protein TusA family
MG974_RS02670	COG0730	response to heat
MG974_RS02675	COG1794	racemase activity, acting on amino acids and derivatives
MG974_RS02690	COG3621	Patatin-like phospholipase
MG974_RS02715	COG0277	FAD linked oxidase domain protein
MG974_RS02745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MG974_RS02760	COG1064	alcohol dehydrogenase
MG974_RS02765	COG0789	Transcriptional regulator
MG974_RS02775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MG974_RS02785	COG2814	Major facilitator Superfamily
MG974_RS02790	COG1309	transcriptional regulator
MG974_RS02795	COG5577	PFAM Coat F domain
MG974_RS02805	COG1063	alcohol dehydrogenase
MG974_RS02810	COG5577	PFAM Coat F domain
MG974_RS02820	COG4585	Histidine kinase
MG974_RS02825	COG2197	response regulator
MG974_RS02830	COG2409	Drug exporters of the RND superfamily
MG974_RS02835	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MG974_RS02840	COG0488	(ABC) transporter
MG974_RS02845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MG974_RS02850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MG974_RS02860	COG2814	Major facilitator Superfamily
MG974_RS02865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MG974_RS02875	COG0730	response to heat
MG974_RS02880	COG0456	acetyltransferase
MG974_RS02885	COG0789	Transcriptional regulator
MG974_RS02885	COG4978	Transcriptional regulator
MG974_RS02890	COG0697	spore germination
MG974_RS02895	COG1051	belongs to the nudix hydrolase family
MG974_RS02900	COG2226	methyltransferase
MG974_RS02905	COG0473	3-isopropylmalate dehydrogenase activity
MG974_RS02910	COG1802	Transcriptional regulator
MG974_RS02915	COG1819	glycosyl
MG974_RS02930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MG974_RS02940	COG1388	LysM domain
MG974_RS02945	COG2814	Major facilitator Superfamily
MG974_RS02950	COG2188	Transcriptional regulator
MG974_RS02955	COG2186	Transcriptional regulator
MG974_RS02960	COG2807	transmembrane transport
MG974_RS02965	COG2076	Multidrug Resistance protein
MG974_RS02970	COG2076	Multidrug Resistance protein
MG974_RS02975	COG1309	transcriptional regulator
MG974_RS02980	COG0531	amino acid
MG974_RS02990	COG3832	glyoxalase III activity
MG974_RS02995	COG0604	alcohol dehydrogenase
MG974_RS03000	COG2814	Major facilitator Superfamily
MG974_RS03040	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MG974_RS03045	COG0802	atpase or kinase
MG974_RS03050	COG1214	PFAM Peptidase M22, glycoprotease
MG974_RS03055	COG0456	acetyltransferase
MG974_RS03060	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MG974_RS03065	COG0488	(ABC) transporter
MG974_RS03080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MG974_RS03085	COG0805	protein transport
MG974_RS03095	COG1266	CAAX protease self-immunity
MG974_RS03155	COG1131	(ABC) transporter
MG974_RS03160	COG0842	Transport permease protein
MG974_RS03165	COG0457	Tetratricopeptide repeat
MG974_RS03170	COG1063	alcohol dehydrogenase
MG974_RS03175	COG2211	Major facilitator Superfamily
MG974_RS03180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MG974_RS03190	COG1842	Phage shock protein A
MG974_RS03195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MG974_RS03200	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MG974_RS03205	COG4260	virion core protein, lumpy skin disease virus
MG974_RS03210	COG2755	lipolytic protein G-D-S-L family
MG974_RS03210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MG974_RS03220	COG1595	DNA-templated transcription, initiation
MG974_RS03225	COG1063	alcohol dehydrogenase
MG974_RS03230	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MG974_RS03235	COG0823	Involved in the tonB-independent uptake of proteins
MG974_RS03250	COG2132	Multicopper oxidase
MG974_RS03255	COG1113	amino acid transport
MG974_RS03260	COG0714	Associated with various cellular activities
MG974_RS03265	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
MG974_RS03270	COG1305	Transglutaminase-like
MG974_RS03310	COG2252	PERMEase
MG974_RS03315	COG3064	Membrane
MG974_RS03335	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MG974_RS03340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MG974_RS03345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MG974_RS03350	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MG974_RS03355	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MG974_RS03370	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MG974_RS03380	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MG974_RS03385	COG0138	bifunctional purine biosynthesis protein purh
MG974_RS03390	COG0151	Belongs to the GarS family
MG974_RS03400	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MG974_RS03405	COG1470	cell adhesion involved in biofilm formation
MG974_RS03410	COG4496	protein, YerC YecD
MG974_RS03415	COG0069	glutamate synthase activity
MG974_RS03425	COG0210	DNA helicase
MG974_RS03435	COG4851	CamS sex pheromone cAM373 precursor
MG974_RS03440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MG974_RS03445	COG1285	pathogenesis
MG974_RS03450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MG974_RS03470	COG1309	transcriptional regulator
MG974_RS03475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MG974_RS03480	COG1597	lipid kinase activity
MG974_RS03485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MG974_RS03495	COG1131	(ABC) transporter
MG974_RS03520	COG5444	nuclease activity
MG974_RS03550	COG3546	catalase activity
MG974_RS03555	COG0454	-acetyltransferase
MG974_RS03565	COG2323	membrane
MG974_RS03570	COG2329	Antibiotic biosynthesis monooxygenase
MG974_RS03580	COG1366	Belongs to the anti-sigma-factor antagonist family
MG974_RS03585	COG5583	Uncharacterized small protein (DUF2292)
MG974_RS03590	COG0196	riboflavin kinase activity
MG974_RS03595	COG0670	Belongs to the BI1 family
MG974_RS03605	COG1846	Transcriptional regulator
MG974_RS03610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MG974_RS03620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MG974_RS03620	COG2124	cytochrome p450
MG974_RS03635	COG1131	(ABC) transporter
MG974_RS03680	COG4106	trans-aconitate 2-methyltransferase activity
MG974_RS03685	COG1368	sulfuric ester hydrolase activity
MG974_RS03690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MG974_RS03695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MG974_RS03700	COG1442	glycosyl transferase family 8
MG974_RS03705	COG1216	Glycosyl transferase, family 2
MG974_RS03710	COG1442	glycosyl transferase family 8
MG974_RS03715	COG2223	nitrite transmembrane transporter activity
MG974_RS03720	COG0531	amino acid
MG974_RS03725	COG1012	belongs to the aldehyde dehydrogenase family
MG974_RS03730	COG0840	transmembrane signaling receptor activity
MG974_RS03735	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS03740	COG0457	Tetratricopeptide repeat
MG974_RS03740	COG0463	Glycosyl transferase, family 2
MG974_RS03745	COG0488	(ABC) transporter
MG974_RS03750	COG0789	Transcriptional regulator
MG974_RS03755	COG2814	Major facilitator Superfamily
MG974_RS03760	COG0488	(ABC) transporter
MG974_RS03765	COG0513	Belongs to the DEAD box helicase family
MG974_RS03775	COG2130	NADP-dependent
MG974_RS03790	COG3866	Pectate lyase
MG974_RS03795	COG0471	metal ion transport
MG974_RS03825	COG2972	Histidine kinase
MG974_RS03825	COG0745	RESPONSE REGULATOR receiver
MG974_RS03835	COG3279	Response regulator of the LytR AlgR family
MG974_RS03845	COG3764	Sortase (surface protein transpeptidase)
MG974_RS03850	COG3290	protein histidine kinase activity
MG974_RS03855	COG4565	transcriptional regulatory protein
MG974_RS03860	COG3181	Tripartite tricarboxylate transporter family receptor
MG974_RS03865	COG2851	Citrate transporter
MG974_RS03870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MG974_RS03875	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MG974_RS03885	COG2258	MOSC domain
MG974_RS03905	COG0024	Methionine aminopeptidase
MG974_RS03910	COG1263	PTS System
MG974_RS03910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MG974_RS03920	COG1368	sulfuric ester hydrolase activity
MG974_RS03930	COG0071	Belongs to the small heat shock protein (HSP20) family
MG974_RS03945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MG974_RS03945	COG1263	PTS System
MG974_RS03950	COG0366	Alpha amylase catalytic
MG974_RS03955	COG2188	Transcriptional regulator
MG974_RS03960	COG0778	Nitroreductase
MG974_RS03975	COG0737	Belongs to the 5'-nucleotidase family
MG974_RS03980	COG0693	protein deglycase activity
MG974_RS03985	COG1609	Transcriptional regulator
MG974_RS04000	COG2814	Major facilitator Superfamily
MG974_RS04010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MG974_RS04015	COG4980	gas vesicle protein
MG974_RS04020	COG1295	ribonuclease BN
MG974_RS04025	COG0477	Major facilitator Superfamily
MG974_RS04030	COG0387	Pfam Sodium calcium exchanger
MG974_RS04040	COG0668	transmembrane transport
MG974_RS04045	COG0535	radical SAM domain protein
MG974_RS04055	COG0726	polysaccharide deacetylase
MG974_RS04060	COG2084	Dehydrogenase
MG974_RS04070	COG0598	Magnesium transport protein CorA
MG974_RS04075	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MG974_RS04080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MG974_RS04090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MG974_RS04095	COG4637	Psort location Cytoplasmic, score
MG974_RS04100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MG974_RS04105	COG0022	dehydrogenase e1 component
MG974_RS04110	COG0508	dehydrogenase complex catalyzes the overall conversion of
MG974_RS04115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MG974_RS04120	COG3284	Transcriptional regulator
MG974_RS04130	COG1486	melibiose metabolic process
MG974_RS04135	COG1737	Transcriptional regulator
MG974_RS04140	COG1263	PTS System
MG974_RS04140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MG974_RS04145	COG1132	(ABC) transporter
MG974_RS04150	COG1132	(ABC) transporter
MG974_RS04155	COG2259	Doxx family
MG974_RS04160	COG2514	catechol 2,3-dioxygenase activity
MG974_RS04170	COG1695	Transcriptional regulator
MG974_RS04175	COG2249	NAD(P)H dehydrogenase (quinone) activity
MG974_RS04180	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MG974_RS04185	COG3848	Pyruvate phosphate dikinase
MG974_RS04185	COG0574	Belongs to the PEP-utilizing enzyme family
MG974_RS04190	COG2732	(Barnase) inhibitor
MG974_RS04195	COG2318	DinB family
MG974_RS04200	COG2814	Major facilitator Superfamily
MG974_RS04205	COG1846	Transcriptional regulator
MG974_RS04210	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MG974_RS04210	COG0392	lysyltransferase activity
MG974_RS04215	COG0384	phenazine biosynthesis protein PhzF
MG974_RS04220	COG0778	Nitroreductase
MG974_RS04235	COG1090	epimerase
MG974_RS04250	COG2814	Major facilitator Superfamily
MG974_RS04260	COG3591	Belongs to the peptidase S1B family
MG974_RS04275	COG3103	Sh3 type 3 domain protein
MG974_RS04280	COG5658	integral membrane protein
MG974_RS04285	COG0596	Alpha beta hydrolase
MG974_RS04290	COG0463	Glycosyl transferase, family 2
MG974_RS04295	COG4485	Bacterial membrane protein, YfhO
MG974_RS04300	COG1988	membrane-bound metal-dependent
MG974_RS04305	COG1194	a g-specific adenine glycosylase
MG974_RS04315	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS04335	COG1132	(ABC) transporter
MG974_RS04340	COG4129	membrane
MG974_RS04350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MG974_RS04355	COG0735	belongs to the Fur family
MG974_RS04470	COG3340	Belongs to the peptidase S51 family
MG974_RS04480	COG0277	FAD linked oxidase domain protein
MG974_RS04490	COG0747	negative chemotaxis
MG974_RS04495	COG0601	transmembrane transport
MG974_RS04500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MG974_RS04505	COG0444	Belongs to the ABC transporter superfamily
MG974_RS04510	COG4608	Belongs to the ABC transporter superfamily
MG974_RS04515	COG0753	catalase activity
MG974_RS04525	COG1116	anion transmembrane transporter activity
MG974_RS04530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MG974_RS04535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MG974_RS04555	COG1476	TRANSCRIPTIONal
MG974_RS04565	COG3382	B3 4 domain protein
MG974_RS04570	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MG974_RS04580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MG974_RS04585	COG0789	Transcriptional regulator
MG974_RS04590	COG1664	Polymer-forming cytoskeletal
MG974_RS04595	COG1664	Polymer-forming cytoskeletal
MG974_RS04600	COG2766	serine protein kinase
MG974_RS04610	COG1846	Transcriptional regulator
MG974_RS04615	COG1566	PFAM secretion protein HlyD family protein
MG974_RS04620	COG2814	Major facilitator Superfamily
MG974_RS04625	COG0655	NAD(P)H dehydrogenase (quinone) activity
MG974_RS04640	COG1725	Transcriptional regulator
MG974_RS04645	COG1131	(ABC) transporter
MG974_RS04650	COG1131	(ABC) transporter
MG974_RS04655	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MG974_RS04660	COG1278	Cold shock
MG974_RS04665	COG1464	Belongs to the NlpA lipoprotein family
MG974_RS04670	COG3706	GGDEF domain
MG974_RS04675	COG1823	symporter activity
MG974_RS04695	COG5577	PFAM Coat F domain
MG974_RS04700	COG0737	Belongs to the 5'-nucleotidase family
MG974_RS04700	COG4085	toxin activity
MG974_RS04700	COG1525	nuclease
MG974_RS04710	COG3764	Sortase (surface protein transpeptidase)
MG974_RS04715	COG0564	pseudouridine synthase activity
MG974_RS04725	COG0517	IMP dehydrogenase activity
MG974_RS04730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MG974_RS04735	COG3153	acetyltransferase
MG974_RS04735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MG974_RS04740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MG974_RS04745	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MG974_RS04750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MG974_RS04760	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MG974_RS04765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MG974_RS04780	COG0431	NADPH-dependent FMN reductase
MG974_RS04795	COG1388	LysM domain
MG974_RS04795	COG0791	NLP P60 protein
MG974_RS04800	COG1959	2 iron, 2 sulfur cluster binding
MG974_RS04810	COG2719	SpoVR family
MG974_RS04815	COG1785	Belongs to the alkaline phosphatase family
MG974_RS04820	COG1388	LysM domain
MG974_RS04820	COG0791	NLP P60 protein
MG974_RS04825	COG0583	DNA-binding transcription factor activity
MG974_RS04830	COG0372	Belongs to the citrate synthase family
MG974_RS04835	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS04840	COG0531	amino acid
MG974_RS04845	COG0733	neurotransmitter:sodium symporter activity
MG974_RS04860	COG1595	DNA-templated transcription, initiation
MG974_RS04865	COG0204	Acyl-transferase
MG974_RS04870	COG1253	flavin adenine dinucleotide binding
MG974_RS04875	COG0789	Transcriptional regulator
MG974_RS04880	COG0436	Aminotransferase
MG974_RS04885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MG974_RS04890	COG1253	flavin adenine dinucleotide binding
MG974_RS04895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MG974_RS04900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MG974_RS04905	COG0584	glycerophosphoryl diester phosphodiesterase
MG974_RS04915	COG0668	transmembrane transport
MG974_RS04920	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MG974_RS04925	COG0726	polysaccharide deacetylase
MG974_RS04930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MG974_RS04935	COG3226	Transcriptional regulator
MG974_RS04945	COG0589	response to stress
MG974_RS04950	COG1132	(ABC) transporter
MG974_RS04955	COG1132	(ABC) transporter
MG974_RS04960	COG0702	epimerase
MG974_RS04980	COG0189	ligase activity
MG974_RS04985	COG0189	ligase activity
MG974_RS05000	COG4335	DNA alkylation repair
MG974_RS05005	COG0561	phosphatase activity
MG974_RS05010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MG974_RS05020	COG0475	glutathione-regulated potassium exporter activity
MG974_RS05025	COG0490	domain, Protein
MG974_RS05035	COG1024	Enoyl-CoA hydratase
MG974_RS05045	COG4152	abc transporter atp-binding protein
MG974_RS05050	COG1668	transmembrane transport
MG974_RS05055	COG0420	3'-5' exonuclease activity
MG974_RS05060	COG4717	serine-type aminopeptidase activity
MG974_RS05075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MG974_RS05110	COG4980	gas vesicle protein
MG974_RS05125	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MG974_RS05130	COG0537	adenosine 5'-monophosphoramidase activity
MG974_RS05135	COG1131	(ABC) transporter
MG974_RS05140	COG4473	ABC transporter
MG974_RS05150	COG1473	amidohydrolase
MG974_RS05155	COG3069	C4-dicarboxylate transmembrane transporter activity
MG974_RS05160	COG2329	Antibiotic biosynthesis monooxygenase
MG974_RS05165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MG974_RS05175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MG974_RS05180	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MG974_RS05185	COG1309	transcriptional regulator
MG974_RS05190	COG1511	domain protein
MG974_RS05195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MG974_RS05205	COG1363	Peptidase, m42
MG974_RS05210	COG1301	dicarboxylic acid transport
MG974_RS05220	COG1234	tRNA 3'-trailer cleavage
MG974_RS05225	COG0095	Lipoate-protein ligase
MG974_RS05230	COG0702	epimerase
MG974_RS05235	COG0318	PFAM AMP-dependent synthetase and ligase
MG974_RS05245	COG0501	Belongs to the peptidase M48B family
MG974_RS05250	COG1404	Belongs to the peptidase S8 family
MG974_RS05255	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MG974_RS05260	COG0406	alpha-ribazole phosphatase activity
MG974_RS05265	COG0183	Belongs to the thiolase family
MG974_RS05270	COG0318	PFAM AMP-dependent synthetase and ligase
MG974_RS05275	COG1268	BioY protein
MG974_RS05280	COG0840	transmembrane signaling receptor activity
MG974_RS05285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MG974_RS05285	COG0723	plastoquinol--plastocyanin reductase activity
MG974_RS05290	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS05300	COG4903	ComK protein
MG974_RS05310	COG5646	InterPro IPR014922
MG974_RS05330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MG974_RS05345	COG0398	Pfam SNARE associated Golgi protein
MG974_RS05350	COG0681	Belongs to the peptidase S26 family
MG974_RS05355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MG974_RS05360	COG1846	Transcriptional regulator
MG974_RS05365	COG3180	Ammonia monooxygenase
MG974_RS05370	COG2814	Major facilitator Superfamily
MG974_RS05380	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MG974_RS05385	COG2323	membrane
MG974_RS05400	COG0420	3'-5' exonuclease activity
MG974_RS05405	COG0419	ATPase involved in DNA repair
MG974_RS05410	COG1403	HNH endonuclease
MG974_RS05450	COG0179	Fumarylacetoacetate (FAA) hydrolase
MG974_RS05470	COG0367	asparagine synthase
MG974_RS05475	COG1562	ergosterol biosynthetic process
MG974_RS05480	COG0534	Mate efflux family protein
MG974_RS05485	COG2207	Transcriptional regulator
MG974_RS05485	COG1917	Cupin 2, conserved barrel domain protein
MG974_RS05490	COG1609	Transcriptional regulator
MG974_RS05495	COG0673	inositol 2-dehydrogenase activity
MG974_RS05500	COG2318	DinB family
MG974_RS05505	COG1357	PFAM Pentapeptide repeats (8 copies)
MG974_RS05510	COG2153	protein acetylation
MG974_RS05515	COG0646	methionine synthase
MG974_RS05515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MG974_RS05525	COG2996	Protein conserved in bacteria
MG974_RS05530	COG1744	ABC transporter substrate-binding protein PnrA-like
MG974_RS05535	COG0840	transmembrane signaling receptor activity
MG974_RS05545	COG1307	EDD domain protein, DegV family
MG974_RS05550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MG974_RS05570	COG0561	phosphatase activity
MG974_RS05575	COG1073	alpha beta
MG974_RS05580	COG2151	metal-sulfur cluster biosynthetic enzyme
MG974_RS05590	COG0277	FAD linked oxidase domain protein
MG974_RS05595	COG2271	Major facilitator Superfamily
MG974_RS05605	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MG974_RS05615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MG974_RS05620	COG0505	Belongs to the CarA family
MG974_RS05625	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MG974_RS05630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MG974_RS05645	COG2267	carboxylic ester hydrolase activity
MG974_RS05655	COG1744	ABC transporter substrate-binding protein PnrA-like
MG974_RS05670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MG974_RS05675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MG974_RS05680	COG5504	Zn-dependent protease
MG974_RS05685	COG0444	Belongs to the ABC transporter superfamily
MG974_RS05690	COG4608	Belongs to the ABC transporter superfamily
MG974_RS05700	COG0601	transmembrane transport
MG974_RS05705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MG974_RS05725	COG0180	Tryptophanyl-tRNA synthetase
MG974_RS05730	COG4166	transmembrane transport
MG974_RS05735	COG0601	transmembrane transport
MG974_RS05740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MG974_RS05745	COG0444	Belongs to the ABC transporter superfamily
MG974_RS05750	COG4608	Belongs to the ABC transporter superfamily
MG974_RS05760	COG0456	acetyltransferase
MG974_RS05765	COG1393	Belongs to the ArsC family
MG974_RS05770	COG0861	Integral membrane protein TerC family
MG974_RS05780	COG4862	establishment of competence for transformation
MG974_RS05785	COG4469	Competence protein
MG974_RS05790	COG1164	Oligoendopeptidase f
MG974_RS05800	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MG974_RS05805	COG2346	COG2346, Truncated hemoglobins
MG974_RS05810	COG0741	lytic transglycosylase activity
MG974_RS05815	COG4116	CYTH
MG974_RS05825	COG2357	RelA SpoT domain protein
MG974_RS05830	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MG974_RS05835	COG0564	pseudouridine synthase activity
MG974_RS05845	COG0475	glutathione-regulated potassium exporter activity
MG974_RS05845	COG0569	domain protein
MG974_RS05850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MG974_RS05855	COG0352	thiamine-phosphate diphosphorylase activity
MG974_RS05860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MG974_RS05865	COG2104	thiamine diphosphate biosynthetic process
MG974_RS05875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MG974_RS05880	COG0351	phosphomethylpyrimidine kinase
MG974_RS05885	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MG974_RS05940	COG0210	DNA helicase
MG974_RS05960	COG1131	(ABC) transporter
MG974_RS05970	COG2153	protein acetylation
MG974_RS05980	COG2382	esterase
MG974_RS05985	COG0626	cystathionine gamma-synthase activity
MG974_RS05990	COG0626	cystathionine gamma-synthase activity
MG974_RS06025	COG5444	nuclease activity
MG974_RS06045	COG1595	DNA-templated transcription, initiation
MG974_RS06070	COG2367	Beta-lactamase
MG974_RS06075	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MG974_RS06080	COG0477	Major facilitator Superfamily
MG974_RS06085	COG1846	Transcriptional regulator
MG974_RS06095	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MG974_RS06100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MG974_RS06105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MG974_RS06110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MG974_RS06110	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MG974_RS06115	COG1447	Phosphotransferase system cellobiose-specific component IIA
MG974_RS06125	COG1349	DNA-binding transcription factor activity
MG974_RS06140	COG1285	pathogenesis
MG974_RS06150	COG2205	protein histidine kinase activity
MG974_RS06160	COG3383	formate dehydrogenase (NAD+) activity
MG974_RS06165	COG2427	Protein of unknown function (DUF1641)
MG974_RS06170	COG2124	cytochrome p450
MG974_RS06175	COG1819	glycosyl
MG974_RS06185	COG1587	Uroporphyrinogen-III synthase
MG974_RS06190	COG0390	transport system, permease component
MG974_RS06195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MG974_RS06200	COG0697	spore germination
MG974_RS06205	COG4297	protein containing double-stranded beta helix domain
MG974_RS06215	COG1252	NADH dehydrogenase
MG974_RS06225	COG2211	Major facilitator Superfamily
MG974_RS06230	COG1609	Transcriptional regulator
MG974_RS06235	COG0246	Mannitol dehydrogenase
MG974_RS06240	COG2721	sulfolactate sulfo-lyase activity
MG974_RS06245	COG0745	RESPONSE REGULATOR receiver
MG974_RS06250	COG2770	Histidine kinase
MG974_RS06250	COG2205	protein histidine kinase activity
MG974_RS06265	COG0730	response to heat
MG974_RS06270	COG2318	DinB family
MG974_RS06275	COG0457	Tetratricopeptide repeat
MG974_RS06285	COG1388	LysM domain
MG974_RS06285	COG3409	Peptidoglycan-binding domain 1 protein
MG974_RS06285	COG5632	N-Acetylmuramoyl-L-alanine amidase
MG974_RS06295	COG4195	phage-related replication protein
MG974_RS06305	COG2856	Zn peptidase
MG974_RS06310	COG1396	sequence-specific DNA binding
MG974_RS06320	COG1522	sequence-specific DNA binding
MG974_RS06325	COG1484	DNA-dependent DNA replication
MG974_RS06345	COG1595	DNA-templated transcription, initiation
MG974_RS06350	COG3728	DNA packaging
MG974_RS06350	COG5484	DNA packaging
MG974_RS06355	COG1783	phage Terminase large subunit
MG974_RS06360	COG5518	Phage portal protein
MG974_RS06365	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MG974_RS06370	COG4653	Phage capsid family
MG974_RS06420	COG5412	phage tail tape measure protein
MG974_RS06420	COG3953	SLT domain
MG974_RS06420	COG5412	phage tail tape measure protein
MG974_RS06420	COG3953	SLT domain
MG974_RS06420	COG3953	SLT domain
MG974_RS06420	COG5412	phage tail tape measure protein
MG974_RS06425	COG1652	LysM domain
MG974_RS06430	COG4193	domain, Protein
MG974_RS06440	COG3628	GPW Gp25 family protein
MG974_RS06445	COG3299	homolog of phage Mu protein gp47
MG974_RS06450	COG3778	Protein conserved in bacteria
MG974_RS06490	COG5632	N-Acetylmuramoyl-L-alanine amidase
MG974_RS06490	COG3409	Peptidoglycan-binding domain 1 protein
MG974_RS06510	COG0306	phosphate transporter
MG974_RS06515	COG1392	Phosphate transport regulator
MG974_RS06520	COG0531	amino acid
MG974_RS06525	COG0346	lactoylglutathione lyase activity
MG974_RS06530	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MG974_RS06535	COG0463	Glycosyl transferase, family 2
MG974_RS06540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MG974_RS06545	COG0477	Major facilitator Superfamily
MG974_RS06550	COG2362	D-Aminopeptidase
MG974_RS06555	COG0601	transmembrane transport
MG974_RS06560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MG974_RS06565	COG0444	Belongs to the ABC transporter superfamily
MG974_RS06570	COG4166	transmembrane transport
MG974_RS06575	COG1619	proteins homologs of microcin C7 resistance protein MccF
MG974_RS06580	COG4948	Mandelate Racemase Muconate Lactonizing
MG974_RS06585	COG0791	NLP P60 protein
MG974_RS06590	COG4608	Belongs to the ABC transporter superfamily
MG974_RS06595	COG2706	6-phosphogluconolactonase activity
MG974_RS06600	COG1834	amidinotransferase
MG974_RS06605	COG1607	acyl-coa hydrolase
MG974_RS06610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MG974_RS06615	COG2076	Multidrug Resistance protein
MG974_RS06620	COG2076	Multidrug Resistance protein
MG974_RS06625	COG0788	formyltetrahydrofolate deformylase activity
MG974_RS06630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MG974_RS06640	COG1764	response to oxidative stress
MG974_RS06645	COG1846	Transcriptional regulator
MG974_RS06650	COG1764	response to oxidative stress
MG974_RS06665	COG0457	Tetratricopeptide repeat
MG974_RS06665	COG0463	Glycosyl transferase, family 2
MG974_RS06675	COG2814	Major facilitator Superfamily
MG974_RS06680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MG974_RS06690	COG1404	Belongs to the peptidase S8 family
MG974_RS06695	COG1366	Belongs to the anti-sigma-factor antagonist family
MG974_RS06700	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MG974_RS06705	COG1122	ATPase activity
MG974_RS06710	COG4721	ABC-type cobalt transport system, permease component
MG974_RS06715	COG1388	LysM domain
MG974_RS06715	COG3858	chitin binding
MG974_RS06725	COG2239	Acts as a magnesium transporter
MG974_RS06730	COG0789	Transcriptional regulator
MG974_RS06745	COG1846	Transcriptional regulator
MG974_RS06750	COG0726	polysaccharide deacetylase
MG974_RS06755	COG1793	dna ligase
MG974_RS06755	COG3285	dna ligase
MG974_RS06760	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MG974_RS06765	COG0586	Pfam SNARE associated Golgi protein
MG974_RS06775	COG1191	sigma factor activity
MG974_RS06800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MG974_RS06805	COG2323	membrane
MG974_RS06815	COG3594	Acyltransferase
MG974_RS06820	COG5002	protein histidine kinase activity
MG974_RS06825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MG974_RS06845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MG974_RS06850	COG0436	Aminotransferase
MG974_RS06880	COG3852	Histidine kinase
MG974_RS06885	COG1846	Transcriptional regulator
MG974_RS06890	COG1360	Flagellar Motor Protein
MG974_RS06895	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MG974_RS06900	COG0542	response to heat
MG974_RS06905	COG3949	Membrane
MG974_RS06920	COG0720	synthase
MG974_RS06925	COG0602	queuosine metabolic process
MG974_RS06940	COG4873	Protein conserved in bacteria
MG974_RS06950	COG3773	Cell wall hydrolase
MG974_RS06955	COG2244	polysaccharide biosynthetic process
MG974_RS06960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG974_RS06965	COG2217	Heavy metal translocating P-type atpase
MG974_RS06970	COG0006	proline dipeptidase activity
MG974_RS06975	COG1609	Transcriptional regulator
MG974_RS06980	COG3711	transcriptional antiterminator
MG974_RS06985	COG1263	PTS System
MG974_RS06985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MG974_RS06985	COG2190	(PTS) system
MG974_RS06990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MG974_RS06995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MG974_RS07005	COG1533	DNA photolyase activity
MG974_RS07010	COG0840	transmembrane signaling receptor activity
MG974_RS07015	COG2084	Dehydrogenase
MG974_RS07020	COG2340	Cysteine-rich secretory protein family
MG974_RS07025	COG0768	penicillin binding
MG974_RS07030	COG4191	Histidine kinase
MG974_RS07035	COG0436	Aminotransferase
MG974_RS07045	COG0784	Response regulator, receiver
MG974_RS07045	COG0835	chemotaxis
MG974_RS07055	COG2814	Major facilitator Superfamily
MG974_RS07060	COG1376	ErfK ybiS ycfS ynhG family protein
MG974_RS07065	COG1408	metallophosphoesterase
MG974_RS07070	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS07080	COG2200	EAL domain
MG974_RS07085	COG4703	Protein of unknown function (DUF1797)
MG974_RS07090	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
MG974_RS07100	COG0517	IMP dehydrogenase activity
MG974_RS07105	COG0583	DNA-binding transcription factor activity
MG974_RS07110	COG0716	FMN binding
MG974_RS07120	COG0716	FMN binding
MG974_RS07140	COG0668	transmembrane transport
MG974_RS07145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG974_RS07165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MG974_RS07170	COG0303	'Molybdopterin
MG974_RS07175	COG1763	Mo-molybdopterin cofactor biosynthetic process
MG974_RS07180	COG0314	molybdopterin synthase activity
MG974_RS07185	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MG974_RS07195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MG974_RS07200	COG1136	(ABC) transporter
MG974_RS07205	COG0577	efflux transmembrane transporter activity
MG974_RS07210	COG1349	DNA-binding transcription factor activity
MG974_RS07215	COG1105	Belongs to the carbohydrate kinase PfkB family
MG974_RS07220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MG974_RS07220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MG974_RS07220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MG974_RS07225	COG0681	Belongs to the peptidase S26 family
MG974_RS07235	COG0488	(ABC) transporter
MG974_RS07240	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MG974_RS07245	COG2309	aminopeptidase activity
MG974_RS07255	COG1077	Cell shape determining protein MreB Mrl
MG974_RS07260	COG2002	toxin-antitoxin pair type II binding
MG974_RS07265	COG3852	Histidine kinase
MG974_RS07270	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MG974_RS07270	COG2105	PFAM AIG2 family protein
MG974_RS07275	COG0569	domain protein
MG974_RS07285	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MG974_RS07295	COG0561	phosphatase activity
MG974_RS07300	COG0242	peptide deformylase activity
MG974_RS07310	COG0497	DNA recombination
MG974_RS07320	COG4221	oxidoreductase activity
MG974_RS07320	COG3321	synthase
MG974_RS07320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS07320	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS07325	COG3321	synthase
MG974_RS07325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG974_RS07325	COG0300	oxidoreductase activity
MG974_RS07325	COG4221	oxidoreductase activity
MG974_RS07330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS07330	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS07330	COG3321	synthase
MG974_RS07330	COG4221	oxidoreductase activity
MG974_RS07335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG974_RS07335	COG0300	oxidoreductase activity
MG974_RS07335	COG3321	synthase
MG974_RS07335	COG4221	oxidoreductase activity
MG974_RS07340	COG0300	oxidoreductase activity
MG974_RS07340	COG4221	oxidoreductase activity
MG974_RS07340	COG3321	synthase
MG974_RS07340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG974_RS07345	COG0300	oxidoreductase activity
MG974_RS07345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG974_RS07345	COG3321	synthase
MG974_RS07345	COG4221	oxidoreductase activity
MG974_RS07350	COG4221	oxidoreductase activity
MG974_RS07350	COG3321	synthase
MG974_RS07350	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS07350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS07355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MG974_RS07360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MG974_RS07365	COG0022	dehydrogenase e1 component
MG974_RS07370	COG0508	dehydrogenase complex catalyzes the overall conversion of
MG974_RS07375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MG974_RS07380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG974_RS07395	COG1982	Orn Lys Arg decarboxylase major
MG974_RS07415	COG0483	inositol monophosphate 1-phosphatase activity
MG974_RS07425	COG3227	Zinc metalloprotease (Elastase)
MG974_RS07440	COG1595	DNA-templated transcription, initiation
MG974_RS07460	COG1217	gtp-binding protein TYPA
MG974_RS07470	COG4896	Protein conserved in bacteria
MG974_RS07480	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MG974_RS07485	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MG974_RS07490	COG2066	Belongs to the glutaminase family
MG974_RS07500	COG0772	Belongs to the SEDS family
MG974_RS07505	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MG974_RS07520	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MG974_RS07520	COG2010	Cytochrome c
MG974_RS07525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MG974_RS07530	COG1845	cytochrome c oxidase, subunit III
MG974_RS07535	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MG974_RS07540	COG3336	cytochrome c oxidase
MG974_RS07550	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MG974_RS07555	COG2340	Cysteine-rich secretory protein family
MG974_RS07570	COG3679	Belongs to the UPF0342 family
MG974_RS07585	COG0742	ribosomal rna small subunit methyltransferase
MG974_RS07595	COG3314	Sporulation integral membrane protein YlbJ
MG974_RS07600	COG1752	Esterase of the alpha-beta hydrolase superfamily
MG974_RS07605	COG3480	Lon protease (S16) C-terminal proteolytic domain
MG974_RS07615	COG1399	metal-binding, possibly nucleic acid-binding protein
MG974_RS07635	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MG974_RS07655	COG4839	cell division protein FtsL
MG974_RS07660	COG0768	penicillin binding
MG974_RS07665	COG0768	penicillin binding
MG974_RS07685	COG0772	Belongs to the SEDS family
MG974_RS07700	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MG974_RS07705	COG0849	cell division
MG974_RS07710	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MG974_RS07715	COG4412	M6 family metalloprotease domain protein
MG974_RS07715	COG1404	Belongs to the peptidase S8 family
MG974_RS07725	COG1191	sigma factor activity
MG974_RS07730	COG1191	sigma factor activity
MG974_RS07735	COG1119	ATPase activity
MG974_RS07740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MG974_RS07745	COG1873	PFAM PRC-barrel domain
MG974_RS07750	COG1496	oxidoreductase activity
MG974_RS07755	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MG974_RS07765	COG0762	integral membrane protein
MG974_RS07770	COG2302	S4 RNA-binding domain
MG974_RS07775	COG3599	regulation of cell shape
MG974_RS07780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MG974_RS07785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MG974_RS07795	COG0564	pseudouridine synthase activity
MG974_RS07805	COG2233	PERMEase
MG974_RS07815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MG974_RS07820	COG0505	Belongs to the CarA family
MG974_RS07825	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MG974_RS07840	COG0284	orotidine-5'-phosphate decarboxylase activity
MG974_RS07845	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MG974_RS07855	COG0306	phosphate transporter
MG974_RS07870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MG974_RS07875	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
MG974_RS07880	COG1648	precorrin-2 dehydrogenase activity
MG974_RS07890	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MG974_RS07895	COG1561	YicC-like family, N-terminal region
MG974_RS07905	COG0194	GDP metabolic process
MG974_RS07915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MG974_RS07920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MG974_RS07925	COG0242	peptide deformylase activity
MG974_RS07935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MG974_RS07935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MG974_RS07945	COG0631	protein serine/threonine phosphatase activity
MG974_RS07950	COG0515	serine threonine protein kinase
MG974_RS07950	COG2815	serine threonine protein kinase
MG974_RS07960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MG974_RS07965	COG1564	THIamine pyrophosphokinase
MG974_RS07980	COG1302	Protein conserved in bacteria
MG974_RS07985	COG1461	Dihydroxyacetone kinase
MG974_RS07990	COG1760	l-serine dehydratase
MG974_RS07995	COG1760	l-serine dehydratase
MG974_RS08000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MG974_RS08015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MG974_RS08020	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS08035	COG1196	nuclear chromosome segregation
MG974_RS08040	COG0552	protein localization to endoplasmic reticulum
MG974_RS08055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MG974_RS08065	COG1837	Belongs to the UPF0109 family
MG974_RS08090	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MG974_RS08105	COG2257	FlhB HrpN YscU SpaS Family
MG974_RS08115	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MG974_RS08120	COG0758	DNA mediated transformation
MG974_RS08125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MG974_RS08135	COG4974	Belongs to the 'phage' integrase family
MG974_RS08155	COG1815	bacterial-type flagellum-dependent cell motility
MG974_RS08160	COG1558	bacterial-type flagellum-dependent cell motility
MG974_RS08165	COG1677	Flagellar hook-basal body complex protein FliE
MG974_RS08170	COG1766	The M ring may be actively involved in energy transduction
MG974_RS08175	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MG974_RS08180	COG1317	bacterial-type flagellum organization
MG974_RS08185	COG1157	protein secretion by the type III secretion system
MG974_RS08190	COG2882	bacterial-type flagellum organization
MG974_RS08195	COG3334	PFAM MgtE intracellular
MG974_RS08200	COG3144	bacterial-type flagellum assembly
MG974_RS08205	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MG974_RS08210	COG4786	Flagellar basal body rod
MG974_RS08215	COG1582	Flagellar protein (FlbD)
MG974_RS08220	COG1580	Controls the rotational direction of flagella during chemotaxis
MG974_RS08225	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MG974_RS08230	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MG974_RS08230	COG1776	CheC inhibitor of MCP methylation
MG974_RS08235	COG2201	protein-glutamate methylesterase activity
MG974_RS08240	COG3190	flagellar
MG974_RS08245	COG1338	Plays a role in the flagellum-specific transport system
MG974_RS08250	COG1987	bacterial-type flagellum assembly
MG974_RS08255	COG1684	flagellar biosynthetic protein fliR
MG974_RS08260	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MG974_RS08265	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MG974_RS08270	COG1419	protein localization to endoplasmic reticulum
MG974_RS08275	COG0455	bacterial-type flagellum organization
MG974_RS08280	COG2201	protein-glutamate methylesterase activity
MG974_RS08285	COG0643	Histidine kinase
MG974_RS08285	COG2198	Histidine kinase
MG974_RS08290	COG0835	chemotaxis
MG974_RS08295	COG1776	CheC inhibitor of MCP methylation
MG974_RS08305	COG1191	sigma factor activity
MG974_RS08335	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MG974_RS08340	COG4589	Belongs to the CDS family
MG974_RS08350	COG0750	zinc metalloprotease
MG974_RS08370	COG0195	Participates in both transcription termination and antitermination
MG974_RS08375	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MG974_RS08380	COG1358	cellular component organization or biogenesis
MG974_RS08390	COG1550	Protein conserved in bacteria
MG974_RS08405	COG0196	riboflavin kinase activity
MG974_RS08420	COG0726	polysaccharide deacetylase
MG974_RS08425	COG0612	Peptidase, M16
MG974_RS08430	COG1873	PFAM PRC-barrel domain
MG974_RS08435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MG974_RS08440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MG974_RS08445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MG974_RS08450	COG0527	aspartate kinase activity
MG974_RS08460	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MG974_RS08465	COG0740	serine-type endopeptidase activity
MG974_RS08475	COG4980	gas vesicle protein
MG974_RS08475	COG1674	ftsk spoiiie
MG974_RS08480	COG2188	Transcriptional regulator
MG974_RS08485	COG2814	Major facilitator Superfamily
MG974_RS08490	COG1846	Transcriptional regulator
MG974_RS08495	COG1033	growth of symbiont in host cell
MG974_RS08495	COG2409	Drug exporters of the RND superfamily
MG974_RS08500	COG0612	Peptidase, M16
MG974_RS08505	COG0612	Peptidase, M16
MG974_RS08510	COG0300	oxidoreductase activity
MG974_RS08525	COG1426	Protein conserved in bacteria
MG974_RS08530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MG974_RS08545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MG974_RS08555	COG1692	metallophosphoesterase
MG974_RS08560	COG2359	stage V sporulation protein S
MG974_RS08580	COG4550	Control of competence regulator ComK, YlbF/YmcA
MG974_RS08625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG974_RS08630	COG3425	synthase
MG974_RS08635	COG1024	Enoyl-CoA hydratase
MG974_RS08640	COG1024	Enoyl-CoA hydratase
MG974_RS08645	COG0300	oxidoreductase activity
MG974_RS08645	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS08645	COG3321	synthase
MG974_RS08645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS08645	COG0318	PFAM AMP-dependent synthetase and ligase
MG974_RS08650	COG4221	oxidoreductase activity
MG974_RS08650	COG3321	synthase
MG974_RS08650	COG0300	oxidoreductase activity
MG974_RS08650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG974_RS08655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG974_RS08655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MG974_RS08655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS08655	COG3321	synthase
MG974_RS08655	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS08655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MG974_RS08655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS08655	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS08655	COG3321	synthase
MG974_RS08655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG974_RS08660	COG4221	oxidoreductase activity
MG974_RS08660	COG3321	synthase
MG974_RS08660	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS08660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS08665	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MG974_RS08665	COG3321	synthase
MG974_RS08665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG974_RS08665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MG974_RS08670	COG2124	cytochrome p450
MG974_RS08675	COG3209	COG3209 Rhs family protein
MG974_RS08680	COG3619	membrane
MG974_RS08690	COG1404	Belongs to the peptidase S8 family
MG974_RS08700	COG4195	phage-related replication protein
MG974_RS08705	COG1764	response to oxidative stress
MG974_RS08715	COG2076	Multidrug Resistance protein
MG974_RS08755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MG974_RS08760	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MG974_RS08765	COG4112	unkown
MG974_RS08770	COG0860	N-Acetylmuramoyl-L-alanine amidase
MG974_RS08775	COG0464	growth
MG974_RS08780	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MG974_RS08785	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MG974_RS08790	COG0789	Transcriptional regulator
MG974_RS08795	COG0174	glutamine synthetase
MG974_RS08840	COG2211	Major facilitator Superfamily
MG974_RS08845	COG3507	Belongs to the glycosyl hydrolase 43 family
MG974_RS08860	COG1070	Carbohydrate kinase
MG974_RS08865	COG3848	Pyruvate phosphate dikinase
MG974_RS08865	COG0574	Belongs to the PEP-utilizing enzyme family
MG974_RS08885	COG1064	alcohol dehydrogenase
MG974_RS08905	COG0456	acetyltransferase
MG974_RS08925	COG3397	chitin binding
MG974_RS08945	COG5434	Belongs to the glycosyl hydrolase 28 family
MG974_RS08950	COG0756	dUTP diphosphatase activity
MG974_RS08955	COG4195	phage-related replication protein
MG974_RS08990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MG974_RS09000	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MG974_RS09020	COG0785	Cytochrome C biogenesis protein
MG974_RS09025	COG2201	protein-glutamate methylesterase activity
MG974_RS09030	COG4846	Membrane protein involved in cytochrome C biogenesis
MG974_RS09040	COG0071	Belongs to the small heat shock protein (HSP20) family
MG974_RS09055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MG974_RS09060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG974_RS09080	COG0824	Thioesterase
MG974_RS09090	COG4841	protein insertion into membrane
MG974_RS09100	COG1832	CoA-binding protein
MG974_RS09105	COG0187	DNA topoisomerase II activity
MG974_RS09110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MG974_RS09120	COG1115	amino acid carrier protein
MG974_RS09130	COG1063	alcohol dehydrogenase
MG974_RS09135	COG0800	Aldolase
MG974_RS09140	COG1312	Catalyzes the dehydration of D-mannonate
MG974_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS09150	COG1609	Transcriptional regulator
MG974_RS09155	COG2271	Major facilitator Superfamily
MG974_RS09200	COG2205	protein histidine kinase activity
MG974_RS09205	COG0745	RESPONSE REGULATOR receiver
MG974_RS09215	COG3507	Belongs to the glycosyl hydrolase 43 family
MG974_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS09245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MG974_RS09250	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MG974_RS09255	COG2610	gluconate transmembrane transporter activity
MG974_RS09260	COG2124	cytochrome p450
MG974_RS09280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MG974_RS09290	COG2246	polysaccharide biosynthetic process
MG974_RS09295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MG974_RS09300	COG0586	Pfam SNARE associated Golgi protein
MG974_RS09305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MG974_RS09310	COG1024	Enoyl-CoA hydratase
MG974_RS09315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MG974_RS09320	COG0511	ligase activity, forming carbon-carbon bonds
MG974_RS09325	COG0439	Biotin carboxylase
MG974_RS09330	COG0318	PFAM AMP-dependent synthetase and ligase
MG974_RS09335	COG1960	acyl-CoA dehydrogenase activity
MG974_RS09340	COG1649	PFAM Uncharacterised BCR, COG1649
MG974_RS09350	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MG974_RS09350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS09355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS09360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS09365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS09370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS09375	COG2027	D-alanyl-D-alanine carboxypeptidase
MG974_RS09380	COG2017	converts alpha-aldose to the beta-anomer
MG974_RS09385	COG0534	Mate efflux family protein
MG974_RS09400	COG0582	viral genome integration into host DNA
MG974_RS09405	COG0166	Belongs to the GPI family
MG974_RS09410	COG0405	Gamma-glutamyltransferase
MG974_RS09415	COG2814	Major facilitator Superfamily
MG974_RS09420	COG0640	Transcriptional regulator
MG974_RS09435	COG0604	alcohol dehydrogenase
MG974_RS09440	COG0493	'glutamate synthase
MG974_RS09445	COG0067	glutamate synthase
MG974_RS09445	COG0069	glutamate synthase activity
MG974_RS09445	COG0070	glutamate synthase
MG974_RS09450	COG0583	DNA-binding transcription factor activity
MG974_RS09455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MG974_RS09470	COG0300	oxidoreductase activity
MG974_RS09475	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MG974_RS09485	COG2814	Major facilitator Superfamily
MG974_RS09490	COG1070	Carbohydrate kinase
MG974_RS09495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MG974_RS09500	COG0243	molybdopterin cofactor binding
MG974_RS09515	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS09520	COG1733	regulation of RNA biosynthetic process
MG974_RS09525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MG974_RS09530	COG2207	Transcriptional regulator
MG974_RS09530	COG0662	Cupin 2, conserved barrel domain protein
MG974_RS09535	COG1309	transcriptional regulator
MG974_RS09540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MG974_RS09550	COG0640	Transcriptional regulator
MG974_RS09555	COG0741	lytic transglycosylase activity
MG974_RS09560	COG2322	membrane
MG974_RS09575	COG1619	proteins homologs of microcin C7 resistance protein MccF
MG974_RS09585	COG1388	LysM domain
MG974_RS09585	COG3584	3D domain protein
MG974_RS09590	COG0514	ATP-dependent DNA helicase (RecQ)
MG974_RS09600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MG974_RS09605	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MG974_RS09620	COG0071	Belongs to the small heat shock protein (HSP20) family
MG974_RS09650	COG1012	belongs to the aldehyde dehydrogenase family
MG974_RS09655	COG1657	PFAM Prenyltransferase squalene oxidase
MG974_RS09660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MG974_RS09665	COG0733	neurotransmitter:sodium symporter activity
MG974_RS09670	COG0385	Bile acid
MG974_RS09675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MG974_RS09680	COG0508	dehydrogenase complex catalyzes the overall conversion of
MG974_RS09690	COG4548	von Willebrand factor, type A
MG974_RS09695	COG0714	Associated with various cellular activities
MG974_RS09700	COG2032	superoxide dismutase activity
MG974_RS09705	COG0791	NLP P60 protein
MG974_RS09705	COG1388	LysM domain
MG974_RS09710	COG1819	glycosyl
MG974_RS09715	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MG974_RS09720	COG0534	Mate efflux family protein
MG974_RS09725	COG1366	Belongs to the anti-sigma-factor antagonist family
MG974_RS09730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MG974_RS09735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MG974_RS09745	COG2962	Rard protein
MG974_RS09760	COG1942	4-Oxalocrotonate Tautomerase
MG974_RS09770	COG1733	regulation of RNA biosynthetic process
MG974_RS09775	COG0778	Nitroreductase
MG974_RS09780	COG0400	carboxylic ester hydrolase activity
MG974_RS09785	COG0346	lactoylglutathione lyase activity
MG974_RS09795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MG974_RS09805	COG2723	6-phospho-beta-galactosidase activity
MG974_RS09810	COG2188	Transcriptional regulator
MG974_RS09815	COG0793	Belongs to the peptidase S41A family
MG974_RS09815	COG3409	Peptidoglycan-binding domain 1 protein
MG974_RS09820	COG2226	methyltransferase
MG974_RS09830	COG1876	peptidase activity
MG974_RS09850	COG0671	phosphoesterase, PA-phosphatase related
MG974_RS09885	COG1509	lysine 2,3-aminomutase activity
MG974_RS09890	COG0456	acetyltransferase
MG974_RS09895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MG974_RS09900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MG974_RS09905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MG974_RS09910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MG974_RS09915	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
MG974_RS09925	COG0456	acetyltransferase
MG974_RS09930	COG0463	Glycosyl transferase, family 2
MG974_RS09945	COG4641	Protein conserved in bacteria
MG974_RS09955	COG1086	Polysaccharide biosynthesis protein
MG974_RS10005	COG1388	LysM domain
MG974_RS10010	COG0457	Tetratricopeptide repeat
MG974_RS10020	COG3391	amine dehydrogenase activity
MG974_RS10065	COG4282	regulation of fungal-type cell wall biogenesis
MG974_RS10070	COG1525	nuclease
MG974_RS10105	COG1846	Transcriptional regulator
MG974_RS10110	COG4698	Protein conserved in bacteria
MG974_RS10115	COG2755	lipolytic protein G-D-S-L family
MG974_RS10120	COG1999	signal sequence binding
MG974_RS10130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MG974_RS10135	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MG974_RS10140	COG1272	protein, Hemolysin III
MG974_RS10145	COG0204	Acyl-transferase
MG974_RS10150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MG974_RS10165	COG2136	Putative SAM-dependent methyltransferase
MG974_RS10165	COG2521	methyltransferase
MG974_RS10180	COG1413	lyase activity
MG974_RS10185	COG1418	mRNA catabolic process
MG974_RS10190	COG0386	Belongs to the glutathione peroxidase family
MG974_RS10200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MG974_RS10210	COG1278	Cold shock
MG974_RS10230	COG0328	RNA-DNA hybrid ribonuclease activity
MG974_RS10235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MG974_RS10240	COG0328	RNA-DNA hybrid ribonuclease activity
MG974_RS10250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MG974_RS10265	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MG974_RS10275	COG1755	Isoprenylcysteine carboxyl methyltransferase
MG974_RS10280	COG3424	synthase
MG974_RS10305	COG1335	isochorismatase
MG974_RS10315	COG2233	PERMEase
MG974_RS10325	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MG974_RS10330	COG1199	ATP-dependent helicase activity
MG974_RS10345	COG0116	Belongs to the methyltransferase superfamily
MG974_RS10375	COG3359	exonuclease
MG974_RS10380	COG1111	helicase
MG974_RS10380	COG1205	dead DEAH box helicase
MG974_RS10385	COG2190	(PTS) system
MG974_RS10390	COG0071	Belongs to the small heat shock protein (HSP20) family
MG974_RS10430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MG974_RS10430	COG4499	WXG100 protein secretion system (Wss), protein YukC
MG974_RS10440	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MG974_RS10445	COG3935	DnaD domain protein
MG974_RS10455	COG0436	Aminotransferase
MG974_RS10460	COG5353	protein conserved in bacteria
MG974_RS10470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MG974_RS10470	COG1199	ATP-dependent helicase activity
MG974_RS10500	COG0438	transferase activity, transferring glycosyl groups
MG974_RS10505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MG974_RS10520	COG1694	Mazg nucleotide pyrophosphohydrolase
MG974_RS10525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MG974_RS10530	COG2140	Oxalate decarboxylase
MG974_RS10540	COG4347	Protein of unknown function (DUF1405)
MG974_RS10545	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MG974_RS10545	COG2010	Cytochrome c
MG974_RS10550	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MG974_RS10555	COG0723	plastoquinol--plastocyanin reductase activity
MG974_RS10570	COG0457	Tetratricopeptide repeat
MG974_RS10580	COG0287	Prephenate dehydrogenase
MG974_RS10615	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MG974_RS10620	COG4401	Chorismate mutase type I
MG974_RS10635	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MG974_RS10640	COG0105	UTP biosynthetic process
MG974_RS10645	COG0142	geranyltranstransferase activity
MG974_RS10655	COG0142	geranyltranstransferase activity
MG974_RS10670	COG0776	regulation of translation
MG974_RS10675	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MG974_RS10715	COG0539	negative regulation of cytoplasmic translation
MG974_RS10730	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
MG974_RS10735	COG2959	enzyme of heme biosynthesis
MG974_RS10740	COG3773	Cell wall hydrolase
MG974_RS10740	COG3409	Peptidoglycan-binding domain 1 protein
MG974_RS10745	COG2339	peptidase activity
MG974_RS10750	COG0492	ferredoxin-NADP+ reductase activity
MG974_RS10755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MG974_RS10760	COG4862	establishment of competence for transformation
MG974_RS10765	COG1408	metallophosphoesterase
MG974_RS10775	COG1388	LysM domain
MG974_RS10780	COG1266	CAAX protease self-immunity
MG974_RS10785	COG0514	ATP-dependent DNA helicase (RecQ)
MG974_RS10790	COG4955	Helix-turn-helix domain
MG974_RS10795	COG1141	Ferredoxin
MG974_RS10800	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MG974_RS10805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MG974_RS10815	COG1595	DNA-templated transcription, initiation
MG974_RS10820	COG5002	protein histidine kinase activity
MG974_RS10825	COG0745	RESPONSE REGULATOR receiver
MG974_RS10830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MG974_RS10835	COG1333	cytochrome c biogenesis protein
MG974_RS10840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG974_RS10845	COG1187	pseudouridine synthase activity
MG974_RS10850	COG0700	Nucleoside recognition
MG974_RS10855	COG2715	membrane protein required for spore maturation
MG974_RS10860	COG1686	Belongs to the peptidase S11 family
MG974_RS10885	COG1547	Domain of unknown function (DUF309)
MG974_RS10890	COG0456	acetyltransferase
MG974_RS10905	COG0307	riboflavin synthase, alpha
MG974_RS10910	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MG974_RS10910	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MG974_RS10920	COG0681	Belongs to the peptidase S26 family
MG974_RS10930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MG974_RS10935	COG4086	secreted protein
MG974_RS10940	COG0019	diaminopimelate decarboxylase activity
MG974_RS10945	COG0697	spore germination
MG974_RS10960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MG974_RS10980	COG1191	sigma factor activity
MG974_RS10990	COG1366	Belongs to the anti-sigma-factor antagonist family
MG974_RS10995	COG1686	Belongs to the peptidase S11 family
MG974_RS11000	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MG974_RS11005	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MG974_RS11010	COG4974	Belongs to the 'phage' integrase family
MG974_RS11020	COG0735	belongs to the Fur family
MG974_RS11025	COG1300	Membrane
MG974_RS11040	COG0281	malic enzyme
MG974_RS11045	COG1757	Na H antiporter
MG974_RS11050	COG1027	Aspartate ammonia-lyase
MG974_RS11055	COG0252	asparaginase activity
MG974_RS11060	COG1396	sequence-specific DNA binding
MG974_RS11065	COG1379	DNA repair
MG974_RS11070	COG0494	nUDIX hydrolase
MG974_RS11080	COG0667	Aldo Keto reductase
MG974_RS11090	COG1073	alpha beta
MG974_RS11100	COG4918	Iron-sulphur cluster biosynthesis
MG974_RS11105	COG0456	acetyltransferase
MG974_RS11105	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MG974_RS11110	COG2329	Antibiotic biosynthesis monooxygenase
MG974_RS11115	COG0456	acetyltransferase
MG974_RS11120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MG974_RS11135	COG0628	permease
MG974_RS11145	COG0346	lactoylglutathione lyase activity
MG974_RS11155	COG3048	D-serine ammonia-lyase activity
MG974_RS11160	COG0300	oxidoreductase activity
MG974_RS11165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MG974_RS11170	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MG974_RS11175	COG1024	Enoyl-CoA hydratase
MG974_RS11180	COG3425	synthase
MG974_RS11185	COG2124	cytochrome p450
MG974_RS11190	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS11190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MG974_RS11190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS11190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG974_RS11190	COG3321	synthase
MG974_RS11195	COG3321	synthase
MG974_RS11195	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS11195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MG974_RS11195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS11195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG974_RS11200	COG3321	synthase
MG974_RS11200	COG0300	oxidoreductase activity
MG974_RS11200	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS11200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS11200	COG0318	PFAM AMP-dependent synthetase and ligase
MG974_RS11205	COG0300	oxidoreductase activity
MG974_RS11205	COG0318	PFAM AMP-dependent synthetase and ligase
MG974_RS11205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS11205	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS11205	COG3321	synthase
MG974_RS11210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MG974_RS11210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS11210	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS11210	COG3321	synthase
MG974_RS11210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG974_RS11215	COG0300	oxidoreductase activity
MG974_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS11215	COG3321	synthase
MG974_RS11215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS11215	COG0318	PFAM AMP-dependent synthetase and ligase
MG974_RS11220	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS11220	COG3321	synthase
MG974_RS11220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MG974_RS11220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS11220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MG974_RS11225	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS11230	COG0318	PFAM AMP-dependent synthetase and ligase
MG974_RS11245	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MG974_RS11245	COG2070	2-Nitropropane dioxygenase
MG974_RS11250	COG0250	Participates in transcription elongation, termination and antitermination
MG974_RS11270	COG0596	Alpha beta hydrolase
MG974_RS11285	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MG974_RS11290	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MG974_RS11305	COG0706	membrane insertase activity
MG974_RS11310	COG2195	Cleaves the N-terminal amino acid of tripeptides
MG974_RS11315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MG974_RS11320	COG0346	lactoylglutathione lyase activity
MG974_RS11330	COG1376	ErfK ybiS ycfS ynhG family protein
MG974_RS11335	COG4129	membrane
MG974_RS11340	COG1126	abc transporter atp-binding protein
MG974_RS11345	COG0765	amino acid transport
MG974_RS11350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MG974_RS11360	COG1597	lipid kinase activity
MG974_RS11365	COG0508	dehydrogenase complex catalyzes the overall conversion of
MG974_RS11370	COG0022	dehydrogenase e1 component
MG974_RS11375	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MG974_RS11380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MG974_RS11385	COG3426	butyrate kinase activity
MG974_RS11390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MG974_RS11395	COG0280	phosphate acetyltransferase
MG974_RS11400	COG3290	protein histidine kinase activity
MG974_RS11400	COG3829	transcription factor binding
MG974_RS11410	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MG974_RS11415	COG2079	MmgE PrpD family protein
MG974_RS11420	COG0372	Belongs to the citrate synthase family
MG974_RS11425	COG1960	acyl-CoA dehydrogenase activity
MG974_RS11430	COG1250	3-hydroxyacyl-CoA dehydrogenase
MG974_RS11435	COG0183	Belongs to the thiolase family
MG974_RS11445	COG0860	N-Acetylmuramoyl-L-alanine amidase
MG974_RS11470	COG1902	pentaerythritol trinitrate reductase activity
MG974_RS11485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MG974_RS11490	COG0745	RESPONSE REGULATOR receiver
MG974_RS11495	COG0750	zinc metalloprotease
MG974_RS11500	COG0497	DNA recombination
MG974_RS11510	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MG974_RS11520	COG0142	geranyltranstransferase activity
MG974_RS11530	COG1570	exodeoxyribonuclease VII activity
MG974_RS11545	COG1302	Protein conserved in bacteria
MG974_RS11550	COG0439	Biotin carboxylase
MG974_RS11555	COG0511	ligase activity, forming carbon-carbon bonds
MG974_RS11595	COG3854	ATPases associated with a variety of cellular activities
MG974_RS11610	COG0006	proline dipeptidase activity
MG974_RS11620	COG3872	metal-dependent enzyme
MG974_RS11630	COG1752	Esterase of the alpha-beta hydrolase superfamily
MG974_RS11645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MG974_RS11665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MG974_RS11680	COG1396	sequence-specific DNA binding
MG974_RS11690	COG0681	Belongs to the peptidase S26 family
MG974_RS11715	COG4940	Competence protein ComGF
MG974_RS11725	COG4970	Tfp pilus assembly protein FimT
MG974_RS11730	COG4537	Required for transformation and DNA binding
MG974_RS11735	COG1459	type II secretion system
MG974_RS11740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MG974_RS11745	COG0598	Magnesium transport protein CorA
MG974_RS11750	COG1253	flavin adenine dinucleotide binding
MG974_RS11755	COG1366	Belongs to the anti-sigma-factor antagonist family
MG974_RS11765	COG1393	Belongs to the ArsC family
MG974_RS11775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MG974_RS11785	COG0011	TIGRFAM Protein of
MG974_RS11795	COG2866	Carboxypeptidase
MG974_RS11800	COG1940	carbohydrate kinase activity
MG974_RS11805	COG4483	Protein conserved in bacteria
MG974_RS11810	COG1757	Na H antiporter
MG974_RS11820	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MG974_RS11835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MG974_RS11840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MG974_RS11845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MG974_RS11850	COG0581	inorganic phosphate transmembrane transporter activity
MG974_RS11855	COG0573	inorganic phosphate transmembrane transporter activity
MG974_RS11860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MG974_RS11865	COG0768	penicillin binding
MG974_RS11870	COG0477	Major facilitator Superfamily
MG974_RS11875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MG974_RS11880	COG2839	Protein conserved in bacteria
MG974_RS11885	COG5521	maltodextrose utilization protein MalA
MG974_RS11890	COG1388	LysM domain
MG974_RS11900	COG4709	membrane
MG974_RS11905	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
MG974_RS11910	COG0735	belongs to the Fur family
MG974_RS11915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MG974_RS11930	COG0513	Belongs to the DEAD box helicase family
MG974_RS11945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MG974_RS11950	COG2384	SAM-dependent methyltransferase
MG974_RS11955	COG2010	Cytochrome c
MG974_RS11960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MG974_RS11965	COG0358	DNA primase activity
MG974_RS11980	COG0517	IMP dehydrogenase activity
MG974_RS11985	COG0751	glycine-tRNA ligase activity
MG974_RS12005	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MG974_RS12010	COG0295	cytidine deaminase activity
MG974_RS12015	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MG974_RS12025	COG1480	7TM receptor with intracellular HD hydrolase
MG974_RS12030	COG1702	phosphate starvation-inducible protein PhoH
MG974_RS12035	COG0561	phosphatase activity
MG974_RS12050	COG4864	UPF0365 protein
MG974_RS12055	COG1030	water channel activity
MG974_RS12060	COG1610	YqeY-like protein
MG974_RS12070	COG1283	sodium-dependent phosphate transmembrane transporter activity
MG974_RS12075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MG974_RS12080	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MG974_RS12110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MG974_RS12125	COG0860	N-Acetylmuramoyl-L-alanine amidase
MG974_RS12155	COG2333	competence protein COMEC
MG974_RS12155	COG0658	competence protein
MG974_RS12160	COG2131	deaminase
MG974_RS12165	COG1555	photosystem II stabilization
MG974_RS12165	COG1596	polysaccharide export
MG974_RS12170	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MG974_RS12175	COG2226	methyltransferase
MG974_RS12180	COG0799	negative regulation of ribosome biogenesis
MG974_RS12185	COG1713	HD superfamily hydrolase involved in NAD metabolism
MG974_RS12195	COG1534	Rna-binding protein
MG974_RS12200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MG974_RS12205	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MG974_RS12210	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MG974_RS12220	COG2755	lipolytic protein G-D-S-L family
MG974_RS12230	COG0398	Pfam SNARE associated Golgi protein
MG974_RS12255	COG2207	Transcriptional regulator
MG974_RS12255	COG3708	Transcriptional regulator
MG974_RS12260	COG0563	adenylate kinase activity
MG974_RS12270	COG2814	Major facilitator Superfamily
MG974_RS12275	COG0456	acetyltransferase
MG974_RS12280	COG2318	DinB family
MG974_RS12290	COG0561	phosphatase activity
MG974_RS12295	COG0561	phosphatase activity
MG974_RS12305	COG1482	cell wall glycoprotein biosynthetic process
MG974_RS12310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MG974_RS12310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MG974_RS12310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MG974_RS12315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MG974_RS12315	COG3711	transcriptional antiterminator
MG974_RS12325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MG974_RS12330	COG0583	DNA-binding transcription factor activity
MG974_RS12335	COG2814	Major facilitator Superfamily
MG974_RS12340	COG2124	cytochrome p450
MG974_RS12340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MG974_RS12345	COG1309	transcriptional regulator
MG974_RS12350	COG2226	methyltransferase
MG974_RS12365	COG2116	formate transmembrane transporter activity
MG974_RS12370	COG5609	conserved protein (DUF2294)
MG974_RS12375	COG3383	formate dehydrogenase (NAD+) activity
MG974_RS12380	COG2427	Protein of unknown function (DUF1641)
MG974_RS12390	COG0626	cystathionine gamma-synthase activity
MG974_RS12395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MG974_RS12420	COG0768	penicillin binding
MG974_RS12435	COG0826	peptidase U32
MG974_RS12440	COG0826	peptidase U32
MG974_RS12445	COG4122	O-methyltransferase activity
MG974_RS12450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MG974_RS12465	COG4472	Bacterial protein of unknown function (DUF965)
MG974_RS12475	COG0628	permease
MG974_RS12480	COG1126	abc transporter atp-binding protein
MG974_RS12485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MG974_RS12490	COG0765	amino acid transport
MG974_RS12495	COG0765	amino acid transport
MG974_RS12510	COG3881	PFAM PRC-barrel domain
MG974_RS12515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MG974_RS12520	COG0457	Tetratricopeptide repeat
MG974_RS12530	COG1104	cysteine desulfurase activity
MG974_RS12535	COG1959	2 iron, 2 sulfur cluster binding
MG974_RS12540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MG974_RS12545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MG974_RS12570	COG3103	Sh3 type 3 domain protein
MG974_RS12570	COG0860	N-Acetylmuramoyl-L-alanine amidase
MG974_RS12570	COG4991	sh3 domain protein
MG974_RS12580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MG974_RS12590	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MG974_RS12590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MG974_RS12595	COG5416	Lipopolysaccharide assembly protein A domain
MG974_RS12600	COG0490	domain, Protein
MG974_RS12605	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MG974_RS12605	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MG974_RS12615	COG2244	polysaccharide biosynthetic process
MG974_RS12620	COG2323	membrane
MG974_RS12630	COG1862	Preprotein translocase
MG974_RS12670	COG1388	LysM domain
MG974_RS12680	COG0157	Belongs to the NadC ModD family
MG974_RS12685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MG974_RS12690	COG1104	cysteine desulfurase activity
MG974_RS12695	COG1827	regulation of RNA biosynthetic process
MG974_RS12700	COG0077	Prephenate dehydratase
MG974_RS12715	COG3290	protein histidine kinase activity
MG974_RS12720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MG974_RS12725	COG2868	ribosomal protein
MG974_RS12735	COG1994	Peptidase M50
MG974_RS12740	COG0739	heme binding
MG974_RS12745	COG2894	cell division
MG974_RS12755	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MG974_RS12765	COG1077	Cell shape determining protein MreB Mrl
MG974_RS12785	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MG974_RS12790	COG0285	dihydrofolate synthase activity
MG974_RS12795	COG0525	valine-tRNA ligase activity
MG974_RS12805	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MG974_RS12810	COG1388	LysM domain
MG974_RS12820	COG0113	porphobilinogen synthase activity
MG974_RS12825	COG1587	Uroporphyrinogen-III synthase
MG974_RS12835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MG974_RS12855	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MG974_RS12860	COG0470	DNA polymerase III
MG974_RS12860	COG1067	ATP-dependent peptidase activity
MG974_RS12875	COG0457	Tetratricopeptide repeat
MG974_RS12875	COG1477	protein flavinylation
MG974_RS12890	COG0473	3-isopropylmalate dehydrogenase activity
MG974_RS12905	COG0440	acetolactate synthase activity
MG974_RS12910	COG0028	Belongs to the TPP enzyme family
MG974_RS12940	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
MG974_RS12960	COG0622	Phosphoesterase
MG974_RS12965	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MG974_RS12975	COG5401	PFAM Sporulation and spore germination
MG974_RS12985	COG1846	Transcriptional regulator
MG974_RS12990	COG2197	response regulator
MG974_RS12995	COG0824	Thioesterase
MG974_RS13000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MG974_RS13005	COG1053	succinate dehydrogenase
MG974_RS13010	COG2009	succinate dehydrogenase
MG974_RS13015	COG1719	4-vinyl reductase, 4VR
MG974_RS13020	COG0527	aspartate kinase activity
MG974_RS13030	COG3118	belongs to the thioredoxin family
MG974_RS13035	COG3534	alpha-L-arabinofuranosidase
MG974_RS13040	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MG974_RS13045	COG2086	electron transfer activity
MG974_RS13050	COG1024	Enoyl-CoA hydratase
MG974_RS13055	COG1309	transcriptional regulator
MG974_RS13060	COG0318	PFAM AMP-dependent synthetase and ligase
MG974_RS13070	COG3766	membrane
MG974_RS13080	COG1796	DNA polymerase
MG974_RS13080	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MG974_RS13085	COG1286	toxin biosynthetic process
MG974_RS13100	COG0072	phenylalanine-tRNA ligase activity
MG974_RS13100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MG974_RS13105	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MG974_RS13110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MG974_RS13120	COG3835	regulator
MG974_RS13125	COG0277	FAD linked oxidase domain protein
MG974_RS13130	COG0247	lactate metabolic process
MG974_RS13135	COG1966	Carbon starvation protein
MG974_RS13140	COG3534	alpha-L-arabinofuranosidase
MG974_RS13145	COG0395	ABC-type sugar transport system, permease component
MG974_RS13150	COG1175	transmembrane transport
MG974_RS13155	COG1653	transport
MG974_RS13165	COG0647	UMP catabolic process
MG974_RS13170	COG0235	Class ii aldolase
MG974_RS13175	COG1069	ribulokinase activity
MG974_RS13180	COG2160	L-arabinose isomerase activity
MG974_RS13185	COG3507	Belongs to the glycosyl hydrolase 43 family
MG974_RS13190	COG1363	Peptidase, m42
MG974_RS13200	COG3326	Membrane
MG974_RS13205	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MG974_RS13215	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MG974_RS13220	COG1346	cytolysis
MG974_RS13225	COG1380	Effector of murein hydrolase LrgA
MG974_RS13230	COG3279	Response regulator of the LytR AlgR family
MG974_RS13235	COG3275	phosphorelay sensor kinase activity
MG974_RS13240	COG1011	Hydrolase
MG974_RS13255	COG0398	Pfam SNARE associated Golgi protein
MG974_RS13260	COG1484	DNA-dependent DNA replication
MG974_RS13265	COG3611	Membrane attachment protein
MG974_RS13280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MG974_RS13285	COG1733	regulation of RNA biosynthetic process
MG974_RS13290	COG2814	Major facilitator Superfamily
MG974_RS13295	COG0656	L-ascorbic acid biosynthetic process
MG974_RS13300	COG0237	dephospho-CoA kinase activity
MG974_RS13305	COG1971	Probably functions as a manganese efflux pump
MG974_RS13310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MG974_RS13315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MG974_RS13315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MG974_RS13320	COG5002	protein histidine kinase activity
MG974_RS13325	COG0745	RESPONSE REGULATOR receiver
MG974_RS13335	COG0538	isocitrate dehydrogenase activity
MG974_RS13340	COG0372	Belongs to the citrate synthase family
MG974_RS13360	COG0628	permease
MG974_RS13365	COG3030	protein affecting phage T7 exclusion by the F plasmid
MG974_RS13370	COG0469	pyruvate kinase activity
MG974_RS13390	COG0281	malic enzyme
MG974_RS13395	COG0587	DNA-directed DNA polymerase activity
MG974_RS13415	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MG974_RS13425	COG4109	DRTGG domain
MG974_RS13435	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS13450	COG0521	Mo-molybdopterin cofactor biosynthetic process
MG974_RS13460	COG0827	DNA restriction-modification system
MG974_RS13465	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MG974_RS13470	COG3874	Sporulation protein YtfJ
MG974_RS13480	COG1714	RDD family
MG974_RS13485	COG0616	signal peptide processing
MG974_RS13490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MG974_RS13495	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MG974_RS13500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MG974_RS13515	COG1104	cysteine desulfurase activity
MG974_RS13520	COG1114	Component of the transport system for branched-chain amino acids
MG974_RS13530	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MG974_RS13535	COG1309	transcriptional regulator
MG974_RS13540	COG1956	GAF domain-containing protein
MG974_RS13545	COG2199	diguanylate cyclase activity
MG974_RS13545	COG2203	Gaf domain
MG974_RS13555	COG1012	belongs to the aldehyde dehydrogenase family
MG974_RS13560	COG4282	regulation of fungal-type cell wall biogenesis
MG974_RS13565	COG1017	nitric oxide dioxygenase activity
MG974_RS13565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MG974_RS13575	COG0693	protein deglycase activity
MG974_RS13590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MG974_RS13595	COG1378	Sugar-specific transcriptional regulator TrmB
MG974_RS13615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MG974_RS13620	COG0454	-acetyltransferase
MG974_RS13625	COG0517	IMP dehydrogenase activity
MG974_RS13630	COG0123	including yeast histone deacetylase and acetoin utilization protein
MG974_RS13635	COG1360	Flagellar Motor Protein
MG974_RS13640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MG974_RS13645	COG1609	Transcriptional regulator
MG974_RS13650	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MG974_RS13650	COG1605	Chorismate mutase
MG974_RS13655	COG3118	belongs to the thioredoxin family
MG974_RS13660	COG4980	gas vesicle protein
MG974_RS13665	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MG974_RS13675	COG1674	ftsk spoiiie
MG974_RS13680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MG974_RS13690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG974_RS13700	COG1363	Peptidase, m42
MG974_RS13705	COG5584	Small secreted protein
MG974_RS13710	COG0281	malic enzyme
MG974_RS13715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MG974_RS13730	COG0510	thiamine kinase activity
MG974_RS13735	COG1597	lipid kinase activity
MG974_RS13745	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MG974_RS13750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MG974_RS13755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MG974_RS13760	COG2252	PERMEase
MG974_RS13765	COG4473	ABC transporter
MG974_RS13770	COG1131	(ABC) transporter
MG974_RS13775	COG1349	DNA-binding transcription factor activity
MG974_RS13780	COG1187	pseudouridine synthase activity
MG974_RS13785	COG2244	polysaccharide biosynthetic process
MG974_RS13790	COG2081	HI0933 family
MG974_RS13795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MG974_RS13805	COG1609	Transcriptional regulator
MG974_RS13810	COG1653	transport
MG974_RS13815	COG1175	transmembrane transport
MG974_RS13820	COG0395	ABC-type sugar transport system, permease component
MG974_RS13825	COG1486	melibiose metabolic process
MG974_RS13835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MG974_RS13850	COG2202	Pas domain
MG974_RS13850	COG1366	Belongs to the anti-sigma-factor antagonist family
MG974_RS13855	COG2814	Major facilitator Superfamily
MG974_RS13860	COG5522	Integral membrane protein (intg_mem_TP0381)
MG974_RS13865	COG0577	efflux transmembrane transporter activity
MG974_RS13870	COG1136	(ABC) transporter
MG974_RS13875	COG2205	protein histidine kinase activity
MG974_RS13880	COG0745	RESPONSE REGULATOR receiver
MG974_RS13885	COG0577	efflux transmembrane transporter activity
MG974_RS13890	COG1136	(ABC) transporter
MG974_RS13910	COG1131	(ABC) transporter
MG974_RS13915	COG1725	Transcriptional regulator
MG974_RS13935	COG0640	Transcriptional regulator
MG974_RS13960	COG0477	Major facilitator Superfamily
MG974_RS13965	COG1242	4 iron, 4 sulfur cluster binding
MG974_RS13970	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MG974_RS13980	COG0584	glycerophosphoryl diester phosphodiesterase
MG974_RS13990	COG2267	carboxylic ester hydrolase activity
MG974_RS13995	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MG974_RS14000	COG1113	amino acid transport
MG974_RS14005	COG0367	asparagine synthase
MG974_RS14025	COG1506	peptidase
MG974_RS14030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MG974_RS14035	COG1116	anion transmembrane transporter activity
MG974_RS14040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MG974_RS14045	COG0494	nUDIX hydrolase
MG974_RS14050	COG4824	toxin secretion phage lysis holin
MG974_RS14055	COG0783	Belongs to the Dps family
MG974_RS14080	COG0288	reversible hydration of carbon dioxide
MG974_RS14090	COG1271	oxidase subunit
MG974_RS14095	COG1294	oxidase, subunit
MG974_RS14105	COG4948	Mandelate Racemase Muconate Lactonizing
MG974_RS14115	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MG974_RS14120	COG0596	Alpha beta hydrolase
MG974_RS14130	COG1169	isochorismate synthase
MG974_RS14135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MG974_RS14140	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
MG974_RS14265	COG3859	Proton-coupled thiamine transporter YuaJ
MG974_RS14270	COG2268	Band 7 protein
MG974_RS14275	COG1585	Membrane protein implicated in regulation of membrane protease activity
MG974_RS14280	COG2318	DinB family
MG974_RS14290	COG1454	alcohol dehydrogenase
MG974_RS14295	COG1012	belongs to the aldehyde dehydrogenase family
MG974_RS14300	COG1510	regulation of RNA biosynthetic process
MG974_RS14310	COG0569	domain protein
MG974_RS14315	COG1705	Flagellar rod assembly protein muramidase FlgJ
MG974_RS14320	COG1017	nitric oxide dioxygenase activity
MG974_RS14320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MG974_RS14340	COG0457	Tetratricopeptide repeat
MG974_RS14365	COG0628	permease
MG974_RS14370	COG0673	inositol 2-dehydrogenase activity
MG974_RS14375	COG0693	protein deglycase activity
MG974_RS14380	COG0840	transmembrane signaling receptor activity
MG974_RS14385	COG0840	transmembrane signaling receptor activity
MG974_RS14390	COG0840	transmembrane signaling receptor activity
MG974_RS14395	COG0840	transmembrane signaling receptor activity
MG974_RS14410	COG2070	2-Nitropropane dioxygenase
MG974_RS14415	COG0432	Pfam Uncharacterised protein family UPF0047
MG974_RS14420	COG0366	Alpha amylase catalytic
MG974_RS14425	COG1253	flavin adenine dinucleotide binding
MG974_RS14430	COG2738	Putative neutral zinc metallopeptidase
MG974_RS14445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MG974_RS14475	COG1335	isochorismatase
MG974_RS14480	COG1979	alcohol dehydrogenase
MG974_RS14485	COG1979	alcohol dehydrogenase
MG974_RS14490	COG2155	Conserved Protein
MG974_RS14495	COG1098	S1 RNA binding domain
MG974_RS14500	COG0436	Aminotransferase
MG974_RS14505	COG1522	sequence-specific DNA binding
MG974_RS14510	COG2267	carboxylic ester hydrolase activity
MG974_RS14520	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MG974_RS14525	COG2205	protein histidine kinase activity
MG974_RS14535	COG5018	Exonuclease
MG974_RS14540	COG2814	Major facilitator Superfamily
MG974_RS14545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MG974_RS14550	COG3011	Protein conserved in bacteria
MG974_RS14560	COG3290	protein histidine kinase activity
MG974_RS14565	COG4565	transcriptional regulatory protein
MG974_RS14570	COG1744	ABC transporter substrate-binding protein PnrA-like
MG974_RS14575	COG3845	ABC transporter
MG974_RS14580	COG4603	Belongs to the binding-protein-dependent transport system permease family
MG974_RS14585	COG1079	Belongs to the binding-protein-dependent transport system permease family
MG974_RS14595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MG974_RS14595	COG2111	Na H antiporter
MG974_RS14600	COG2111	Na H antiporter
MG974_RS14605	COG1006	Multisubunit Na H antiporter MnhC subunit
MG974_RS14610	COG0651	ATP synthesis coupled electron transport
MG974_RS14615	COG1863	multisubunit Na H antiporter MnhE subunit
MG974_RS14620	COG2212	antiporter activity
MG974_RS14625	COG1320	monovalent cation:proton antiporter activity
MG974_RS14630	COG2050	protein possibly involved in aromatic compounds catabolism
MG974_RS14635	COG2197	response regulator
MG974_RS14640	COG4585	Histidine kinase
MG974_RS14650	COG0142	geranyltranstransferase activity
MG974_RS14665	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MG974_RS14670	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MG974_RS14675	COG1335	isochorismatase
MG974_RS14680	COG5506	Protein of unknown function (DUF1694)
MG974_RS14695	COG0628	permease
MG974_RS14705	COG1418	mRNA catabolic process
MG974_RS14710	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS14720	COG1511	domain protein
MG974_RS14725	COG0433	COG0433 Predicted ATPase
MG974_RS14725	COG1674	ftsk spoiiie
MG974_RS14730	COG4499	WXG100 protein secretion system (Wss), protein YukC
MG974_RS14735	COG5417	Belongs to the EsaB family
MG974_RS14740	COG4842	Belongs to the WXG100 family
MG974_RS14745	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MG974_RS14745	COG2508	Transcriptional regulator
MG974_RS14750	COG0686	Belongs to the AlaDH PNT family
MG974_RS14755	COG5634	Uncharacterized conserved protein (DUF2278)
MG974_RS14760	COG3251	PFAM MbtH domain protein
MG974_RS14765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MG974_RS14770	COG1535	isochorismatase
MG974_RS14770	COG3433	isochorismatase activity
MG974_RS14775	COG1021	2,3-dihydroxybenzoate-AMP ligase
MG974_RS14780	COG1169	isochorismate synthase
MG974_RS14785	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS14790	COG2819	hydrolase of the alpha beta superfamily
MG974_RS14795	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MG974_RS14800	COG1268	BioY protein
MG974_RS14805	COG2056	Na+-H+ antiporter family
MG974_RS14815	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
MG974_RS14820	COG3584	3D domain protein
MG974_RS14835	COG1252	NADH dehydrogenase
MG974_RS14865	COG1131	(ABC) transporter
MG974_RS14890	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MG974_RS14895	COG0316	Belongs to the HesB IscA family
MG974_RS14905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MG974_RS14915	COG1252	NADH dehydrogenase
MG974_RS14920	COG4837	Protein of unknown function (DUF1462)
MG974_RS14925	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MG974_RS14930	COG0823	Involved in the tonB-independent uptake of proteins
MG974_RS14930	COG1506	peptidase
MG974_RS14930	COG4946	Tricorn protease homolog
MG974_RS14940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MG974_RS14945	COG0460	homoserine dehydrogenase
MG974_RS14950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MG974_RS14955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MG974_RS14960	COG0647	UMP catabolic process
MG974_RS14965	COG2445	Protein of unknown function DUF86
MG974_RS14970	COG4470	Protein conserved in bacteria
MG974_RS14980	COG0739	heme binding
MG974_RS14990	COG0737	Belongs to the 5'-nucleotidase family
MG974_RS14995	COG0730	response to heat
MG974_RS15000	COG1801	Protein of unknown function DUF72
MG974_RS15015	COG2508	Transcriptional regulator
MG974_RS15030	COG2814	Major facilitator Superfamily
MG974_RS15035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MG974_RS15040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MG974_RS15045	COG2356	endonuclease I
MG974_RS15050	COG3842	ATPase activity
MG974_RS15055	COG2188	Transcriptional regulator
MG974_RS15060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MG974_RS15065	COG0395	ABC-type sugar transport system, permease component
MG974_RS15070	COG1175	transmembrane transport
MG974_RS15075	COG1653	transport
MG974_RS15080	COG2222	sugar isomerase
MG974_RS15085	COG0789	Transcriptional regulator
MG974_RS15095	COG0322	excinuclease ABC activity
MG974_RS15100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MG974_RS15110	COG3409	Peptidoglycan-binding domain 1 protein
MG974_RS15115	COG0719	Fe-S assembly protein
MG974_RS15120	COG0822	iron-sulfur transferase activity
MG974_RS15125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MG974_RS15130	COG0719	Fe-S assembly protein
MG974_RS15135	COG0396	ATPase activity
MG974_RS15145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MG974_RS15150	COG1464	Belongs to the NlpA lipoprotein family
MG974_RS15155	COG2011	ABC-type metal ion transport system permease component
MG974_RS15160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MG974_RS15170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MG974_RS15175	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MG974_RS15190	COG1393	Belongs to the ArsC family
MG974_RS15195	COG1960	acyl-CoA dehydrogenase activity
MG974_RS15200	COG0183	Belongs to the thiolase family
MG974_RS15205	COG1024	Enoyl-CoA hydratase
MG974_RS15205	COG1250	3-hydroxyacyl-CoA dehydrogenase
MG974_RS15225	COG5577	PFAM Coat F domain
MG974_RS15230	COG1846	Transcriptional regulator
MG974_RS15235	COG0477	Major facilitator Superfamily
MG974_RS15240	COG0583	DNA-binding transcription factor activity
MG974_RS15260	COG1120	ATPase activity
MG974_RS15275	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS15280	COG0783	Belongs to the Dps family
MG974_RS15285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MG974_RS15290	COG0745	RESPONSE REGULATOR receiver
MG974_RS15295	COG2205	protein histidine kinase activity
MG974_RS15295	COG2770	Histidine kinase
MG974_RS15305	COG1309	transcriptional regulator
MG974_RS15310	COG0114	fumarate hydratase activity
MG974_RS15320	COG0697	spore germination
MG974_RS15325	COG0814	amino acid
MG974_RS15335	COG2197	response regulator
MG974_RS15340	COG4585	Histidine kinase
MG974_RS15345	COG4758	membrane
MG974_RS15350	COG3595	metallopeptidase activity
MG974_RS15355	COG1842	Phage shock protein A
MG974_RS15360	COG4758	membrane
MG974_RS15365	COG2814	Major facilitator Superfamily
MG974_RS15370	COG2096	Adenosyltransferase
MG974_RS15375	COG1120	ATPase activity
MG974_RS15380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MG974_RS15385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MG974_RS15390	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS15395	COG3386	PFAM SMP-30 Gluconolaconase
MG974_RS15400	COG2205	protein histidine kinase activity
MG974_RS15405	COG0745	RESPONSE REGULATOR receiver
MG974_RS15415	COG1191	sigma factor activity
MG974_RS15425	COG2140	Oxalate decarboxylase
MG974_RS15435	COG1120	ATPase activity
MG974_RS15440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MG974_RS15445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MG974_RS15450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MG974_RS15455	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MG974_RS15460	COG0531	amino acid
MG974_RS15470	COG1988	membrane-bound metal-dependent
MG974_RS15475	COG1368	sulfuric ester hydrolase activity
MG974_RS15480	COG1910	domain protein
MG974_RS15485	COG0725	ABC transporter, periplasmic molybdate-binding protein
MG974_RS15490	COG4149	molybdate abc transporter
MG974_RS15495	COG2197	response regulator
MG974_RS15500	COG3850	Histidine kinase
MG974_RS15505	COG1131	(ABC) transporter
MG974_RS15515	COG0842	Transport permease protein
MG974_RS15520	COG0656	L-ascorbic acid biosynthetic process
MG974_RS15540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MG974_RS15545	COG3973	AAA domain
MG974_RS15550	COG2860	membrane
MG974_RS15560	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MG974_RS15565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MG974_RS15570	COG2217	Heavy metal translocating P-type atpase
MG974_RS15575	COG2217	Heavy metal translocating P-type atpase
MG974_RS15580	COG2608	mercury ion transmembrane transporter activity
MG974_RS15585	COG1937	Protein conserved in bacteria
MG974_RS15590	COG0673	inositol 2-dehydrogenase activity
MG974_RS15600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MG974_RS15605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MG974_RS15610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MG974_RS15615	COG1126	abc transporter atp-binding protein
MG974_RS15620	COG0765	amino acid transport
MG974_RS15625	COG0765	amino acid transport
MG974_RS15630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MG974_RS15635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MG974_RS15640	COG0454	-acetyltransferase
MG974_RS15645	COG0583	DNA-binding transcription factor activity
MG974_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS15655	COG2732	(Barnase) inhibitor
MG974_RS15670	COG0557	exoribonuclease II activity
MG974_RS15675	COG1647	Serine aminopeptidase, S33
MG974_RS15680	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MG974_RS15685	COG1476	TRANSCRIPTIONal
MG974_RS15690	COG1396	sequence-specific DNA binding
MG974_RS15695	COG1396	sequence-specific DNA binding
MG974_RS15700	COG1733	regulation of RNA biosynthetic process
MG974_RS15725	COG1131	(ABC) transporter
MG974_RS15730	COG1174	glycine betaine transport
MG974_RS15735	COG1732	Glycine betaine
MG974_RS15740	COG1174	glycine betaine transport
MG974_RS15745	COG1125	glycine betaine transport
MG974_RS15745	COG0517	IMP dehydrogenase activity
MG974_RS15750	COG1510	regulation of RNA biosynthetic process
MG974_RS15755	COG1174	glycine betaine transport
MG974_RS15760	COG1732	Glycine betaine
MG974_RS15765	COG1174	glycine betaine transport
MG974_RS15770	COG1125	glycine betaine transport
MG974_RS15770	COG0517	IMP dehydrogenase activity
MG974_RS15775	COG1510	regulation of RNA biosynthetic process
MG974_RS15780	COG2095	MarC family integral membrane protein
MG974_RS15785	COG3064	Membrane
MG974_RS15790	COG4640	response to antibiotic
MG974_RS15795	COG0456	acetyltransferase
MG974_RS15810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MG974_RS15825	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MG974_RS15830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MG974_RS15835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MG974_RS15845	COG2234	aminopeptidase activity
MG974_RS15865	COG0126	phosphoglycerate kinase activity
MG974_RS15870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MG974_RS15875	COG2390	Transcriptional regulator
MG974_RS15880	COG2814	Major facilitator Superfamily
MG974_RS15885	COG1609	Transcriptional regulator
MG974_RS15890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MG974_RS15895	COG0583	DNA-binding transcription factor activity
MG974_RS15900	COG0697	spore germination
MG974_RS15905	COG1113	amino acid transport
MG974_RS15910	COG1737	Transcriptional regulator
MG974_RS15915	COG1070	Carbohydrate kinase
MG974_RS15940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MG974_RS15945	COG2186	Transcriptional regulator
MG974_RS15950	COG1620	l-lactate permease
MG974_RS15955	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MG974_RS15965	COG5039	Polysaccharide pyruvyl transferase
MG974_RS15970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MG974_RS15975	COG0110	maltose O-acetyltransferase activity
MG974_RS15980	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MG974_RS15985	COG2244	polysaccharide biosynthetic process
MG974_RS15990	COG1216	Glycosyl transferase, family 2
MG974_RS15995	COG5039	Polysaccharide pyruvyl transferase
MG974_RS16000	COG1216	Glycosyl transferase, family 2
MG974_RS16010	COG0438	transferase activity, transferring glycosyl groups
MG974_RS16015	COG1215	transferase activity, transferring glycosyl groups
MG974_RS16020	COG0438	transferase activity, transferring glycosyl groups
MG974_RS16025	COG1086	Polysaccharide biosynthesis protein
MG974_RS16030	COG0489	protein tyrosine kinase activity
MG974_RS16035	COG3944	biosynthesis protein
MG974_RS16040	COG1396	sequence-specific DNA binding
MG974_RS16045	COG2272	Belongs to the type-B carboxylesterase lipase family
MG974_RS16055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MG974_RS16060	COG2364	Membrane
MG974_RS16065	COG0456	acetyltransferase
MG974_RS16070	COG3479	Phenolic acid decarboxylase
MG974_RS16110	COG2223	nitrite transmembrane transporter activity
MG974_RS16115	COG1609	Transcriptional regulator
MG974_RS16125	COG0583	DNA-binding transcription factor activity
MG974_RS16130	COG2828	Protein conserved in bacteria
MG974_RS16135	COG2814	Major facilitator Superfamily
MG974_RS16135	COG0477	Major facilitator Superfamily
MG974_RS16140	COG1611	Belongs to the LOG family
MG974_RS16145	COG1694	Mazg nucleotide pyrophosphohydrolase
MG974_RS16150	COG0659	secondary active sulfate transmembrane transporter activity
MG974_RS16155	COG0288	reversible hydration of carbon dioxide
MG974_RS16160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MG974_RS16165	COG4290	ribonuclease
MG974_RS16170	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MG974_RS16175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MG974_RS16185	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MG974_RS16195	COG1051	belongs to the nudix hydrolase family
MG974_RS16200	COG0492	ferredoxin-NADP+ reductase activity
MG974_RS16205	COG3883	PFAM NLP P60 protein
MG974_RS16205	COG0791	NLP P60 protein
MG974_RS16210	COG0457	Tetratricopeptide repeat
MG974_RS16215	COG5002	protein histidine kinase activity
MG974_RS16220	COG0745	RESPONSE REGULATOR receiver
MG974_RS16230	COG1132	(ABC) transporter
MG974_RS16235	COG0140	phosphoribosyl-ATP diphosphatase activity
MG974_RS16235	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MG974_RS16260	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MG974_RS16275	COG4990	cell redox homeostasis
MG974_RS16280	COG0110	maltose O-acetyltransferase activity
MG974_RS16300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MG974_RS16310	COG2188	Transcriptional regulator
MG974_RS16315	COG1309	transcriptional regulator
MG974_RS16320	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MG974_RS16325	COG1950	PFAM Membrane protein of
MG974_RS16330	COG1983	PspC domain protein
MG974_RS16335	COG3595	metallopeptidase activity
MG974_RS16350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MG974_RS16360	COG4897	Protein conserved in bacteria
MG974_RS16365	COG0574	Belongs to the PEP-utilizing enzyme family
MG974_RS16365	COG3848	Pyruvate phosphate dikinase
MG974_RS16370	COG1309	transcriptional regulator
MG974_RS16375	COG2814	Major facilitator Superfamily
MG974_RS16385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MG974_RS16395	COG0793	Belongs to the peptidase S41A family
MG974_RS16395	COG3409	Peptidoglycan-binding domain 1 protein
MG974_RS16400	COG3420	alginic acid biosynthetic process
MG974_RS16405	COG2177	Part of the ABC transporter FtsEX involved in
MG974_RS16410	COG2884	Cell division ATP-binding protein ftsE
MG974_RS16415	COG2010	Cytochrome c
MG974_RS16420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MG974_RS16435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MG974_RS16450	COG1516	flagellar protein fliS
MG974_RS16455	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MG974_RS16460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MG974_RS16480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MG974_RS16485	COG4786	Flagellar basal body rod
MG974_RS16485	COG1256	bacterial-type flagellum assembly
MG974_RS16490	COG3418	PFAM FlgN family protein
MG974_RS16495	COG2747	anti-sigma28 factor FlgM
MG974_RS16505	COG1040	competence protein
MG974_RS16515	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MG974_RS16520	COG1307	EDD domain protein, DegV family
MG974_RS16525	COG2197	response regulator
MG974_RS16530	COG4585	Histidine kinase
MG974_RS16535	COG1739	Uncharacterized protein family UPF0029
MG974_RS16540	COG1316	TRANSCRIPTIONal
MG974_RS16545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MG974_RS16550	COG0438	transferase activity, transferring glycosyl groups
MG974_RS16555	COG1215	transferase activity, transferring glycosyl groups
MG974_RS16560	COG3206	protein involved in exopolysaccharide biosynthesis
MG974_RS16565	COG3307	-O-antigen
MG974_RS16570	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MG974_RS16575	COG0438	transferase activity, transferring glycosyl groups
MG974_RS16575	COG0297	glycogen (starch) synthase activity
MG974_RS16580	COG2244	polysaccharide biosynthetic process
MG974_RS16590	COG2247	cell wall binding repeat
MG974_RS16590	COG0860	N-Acetylmuramoyl-L-alanine amidase
MG974_RS16595	COG2247	cell wall binding repeat
MG974_RS16595	COG2385	sporulation resulting in formation of a cellular spore
MG974_RS16605	COG1316	TRANSCRIPTIONal
MG974_RS16610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MG974_RS16615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MG974_RS16620	COG1134	teichoic acid transport
MG974_RS16625	COG1682	transport, permease protein
MG974_RS16630	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MG974_RS16640	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MG974_RS16645	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MG974_RS16650	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MG974_RS16655	COG4193	domain, Protein
MG974_RS16660	COG1482	cell wall glycoprotein biosynthetic process
MG974_RS16665	COG0697	spore germination
MG974_RS16670	COG0814	amino acid
MG974_RS16680	COG1215	transferase activity, transferring glycosyl groups
MG974_RS16685	COG2814	Major facilitator Superfamily
MG974_RS16690	COG1316	TRANSCRIPTIONal
MG974_RS16695	COG0561	phosphatase activity
MG974_RS16700	COG2433	Pfam Transposase IS66
MG974_RS16705	COG0791	NLP P60 protein
MG974_RS16715	COG2843	Capsule synthesis protein
MG974_RS16725	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MG974_RS16730	COG0697	spore germination
MG974_RS16735	COG0814	amino acid
MG974_RS16745	COG1609	Transcriptional regulator
MG974_RS16750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MG974_RS16760	COG1129	ABC transporter
MG974_RS16765	COG1172	Belongs to the binding-protein-dependent transport system permease family
MG974_RS16770	COG1879	ABC-type sugar transport system periplasmic component
MG974_RS16775	COG3103	Sh3 type 3 domain protein
MG974_RS16780	COG2249	NAD(P)H dehydrogenase (quinone) activity
MG974_RS16785	COG3527	Alpha-acetolactate decarboxylase
MG974_RS16790	COG0028	Belongs to the TPP enzyme family
MG974_RS16795	COG0583	DNA-binding transcription factor activity
MG974_RS16800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MG974_RS16815	COG5337	Spore coat protein CotH
MG974_RS16825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MG974_RS16835	COG0405	Gamma-glutamyltransferase
MG974_RS16840	COG1522	sequence-specific DNA binding
MG974_RS16845	COG2059	Chromate
MG974_RS16850	COG2059	Chromate
MG974_RS16860	COG0655	NAD(P)H dehydrogenase (quinone) activity
MG974_RS16865	COG0583	DNA-binding transcription factor activity
MG974_RS16905	COG5444	nuclease activity
MG974_RS16920	COG3878	Protein conserved in bacteria
MG974_RS16925	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MG974_RS16930	COG4464	protein tyrosine phosphatase activity
MG974_RS16935	COG0489	protein tyrosine kinase activity
MG974_RS16940	COG3944	biosynthesis protein
MG974_RS16950	COG4715	Zinc finger, swim domain protein
MG974_RS16955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MG974_RS16960	COG0561	phosphatase activity
MG974_RS16965	COG1349	DNA-binding transcription factor activity
MG974_RS16970	COG0629	single-stranded DNA binding
MG974_RS16995	COG0457	Tetratricopeptide repeat
MG974_RS17000	COG4786	Flagellar basal body rod
MG974_RS17005	COG4786	Flagellar basal body rod
MG974_RS17010	COG1077	Cell shape determining protein MreB Mrl
MG974_RS17015	COG1609	Transcriptional regulator
MG974_RS17020	COG1846	Transcriptional regulator
MG974_RS17025	COG2814	Major facilitator Superfamily
MG974_RS17030	COG1953	Uracil, thiamine, allantoin
MG974_RS17035	COG0477	Major facilitator Superfamily
MG974_RS17040	COG1335	isochorismatase
MG974_RS17045	COG0004	ammonium transporteR
MG974_RS17050	COG0347	Belongs to the P(II) protein family
MG974_RS17055	COG0772	Belongs to the SEDS family
MG974_RS17060	COG0671	phosphoesterase, PA-phosphatase related
MG974_RS17070	COG0739	heme binding
MG974_RS17075	COG1247	-acetyltransferase
MG974_RS17090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MG974_RS17100	COG0726	polysaccharide deacetylase
MG974_RS17110	COG1959	2 iron, 2 sulfur cluster binding
MG974_RS17125	COG0831	urea catabolic process
MG974_RS17130	COG3237	CsbD-like
MG974_RS17135	COG1994	Peptidase M50
MG974_RS17140	COG0457	Tetratricopeptide repeat
MG974_RS17150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MG974_RS17160	COG2304	oxidoreductase activity
MG974_RS17165	COG2304	oxidoreductase activity
MG974_RS17170	COG2385	sporulation resulting in formation of a cellular spore
MG974_RS17175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MG974_RS17185	COG4836	Membrane
MG974_RS17255	COG0698	ribose 5-phosphate isomerase
MG974_RS17260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MG974_RS17270	COG0009	L-threonylcarbamoyladenylate synthase
MG974_RS17275	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MG974_RS17295	COG2890	protein-(glutamine-N5) methyltransferase activity
MG974_RS17300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MG974_RS17305	COG0346	lactoylglutathione lyase activity
MG974_RS17310	COG0789	Transcriptional regulator
MG974_RS17315	COG0679	Auxin Efflux Carrier
MG974_RS17320	COG0281	malic enzyme
MG974_RS17335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MG974_RS17345	COG1494	fructose-1,6-bisphosphatase
MG974_RS17350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MG974_RS17360	COG0191	fructose-bisphosphate aldolase activity
MG974_RS17365	COG2204	response regulator
MG974_RS17370	COG4821	SIS domain
MG974_RS17385	COG2181	nitrate reductase activity
MG974_RS17385	COG0247	lactate metabolic process
MG974_RS17390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MG974_RS17405	COG1132	(ABC) transporter
MG974_RS17410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MG974_RS17420	COG2181	nitrate reductase activity
MG974_RS17425	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MG974_RS17430	COG1140	nitrate reductase beta subunit
MG974_RS17435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MG974_RS17440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MG974_RS17450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MG974_RS17455	COG2223	nitrite transmembrane transporter activity
MG974_RS17465	COG4506	Protein conserved in bacteria
MG974_RS17470	COG0457	Tetratricopeptide repeat
MG974_RS17510	COG0010	Belongs to the arginase family
MG974_RS17515	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MG974_RS17520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MG974_RS17535	COG1994	Peptidase M50
MG974_RS17540	COG1942	4-Oxalocrotonate Tautomerase
MG974_RS17545	COG1846	Transcriptional regulator
MG974_RS17550	COG0531	amino acid
MG974_RS17555	COG3465	dGTPase activity
MG974_RS17560	COG1078	dGTPase activity
MG974_RS17575	COG1695	Transcriptional regulator
MG974_RS17585	COG1131	(ABC) transporter
MG974_RS17590	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MG974_RS17620	COG0583	DNA-binding transcription factor activity
MG974_RS17625	COG2855	membrane
MG974_RS17630	COG0280	phosphate acetyltransferase
MG974_RS17640	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS17645	COG0436	Aminotransferase
MG974_RS17675	COG2814	Major facilitator Superfamily
MG974_RS17680	COG2814	Major facilitator Superfamily
MG974_RS17685	COG0833	amino acid
MG974_RS17690	COG4187	Peptidase family M20/M25/M40
MG974_RS17695	COG1012	belongs to the aldehyde dehydrogenase family
MG974_RS17700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MG974_RS17710	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MG974_RS17715	COG1091	dTDP-4-dehydrorhamnose reductase activity
MG974_RS17720	COG1088	dTDP-glucose 4,6-dehydratase activity
MG974_RS17725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MG974_RS17730	COG3980	spore coat polysaccharide biosynthesis protein
MG974_RS17735	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
MG974_RS17740	COG2089	acid synthase
MG974_RS17745	COG0456	acetyltransferase
MG974_RS17750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MG974_RS17755	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MG974_RS17760	COG0463	Glycosyl transferase, family 2
MG974_RS17770	COG2363	Small membrane protein
MG974_RS17775	COG2233	PERMEase
MG974_RS17790	COG1216	Glycosyl transferase, family 2
MG974_RS17805	COG1695	Transcriptional regulator
MG974_RS17810	COG0351	phosphomethylpyrimidine kinase
MG974_RS17820	COG1621	beta-fructofuranosidase activity
MG974_RS17825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MG974_RS17825	COG1263	PTS System
MG974_RS17830	COG3711	transcriptional antiterminator
MG974_RS17840	COG1404	Belongs to the peptidase S8 family
MG974_RS17845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MG974_RS17850	COG0778	Nitroreductase
MG974_RS17855	COG0772	Belongs to the SEDS family
MG974_RS17860	COG0454	-acetyltransferase
MG974_RS17880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MG974_RS17885	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MG974_RS17890	COG2261	transglycosylase associated protein
MG974_RS17895	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MG974_RS17905	COG2246	polysaccharide biosynthetic process
MG974_RS17910	COG1309	transcriptional regulator
MG974_RS17930	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MG974_RS17935	COG2837	iron assimilation
MG974_RS17955	COG0583	DNA-binding transcription factor activity
MG974_RS17965	COG1346	cytolysis
MG974_RS17970	COG4895	conserved protein (DUF2196)
MG974_RS17975	COG0789	Transcriptional regulator
MG974_RS17980	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MG974_RS17985	COG0346	lactoylglutathione lyase activity
MG974_RS17990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MG974_RS17995	COG1404	Belongs to the peptidase S8 family
MG974_RS18000	COG1442	glycosyl transferase family 8
MG974_RS18005	COG1846	Transcriptional regulator
MG974_RS18010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MG974_RS18015	COG2357	RelA SpoT domain protein
MG974_RS18020	COG1575	Belongs to the MenA family. Type 1 subfamily
MG974_RS18035	COG1696	Membrane protein involved in D-alanine export
MG974_RS18045	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MG974_RS18050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MG974_RS18055	COG1486	melibiose metabolic process
MG974_RS18060	COG1447	Phosphotransferase system cellobiose-specific component IIA
MG974_RS18065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MG974_RS18070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MG974_RS18075	COG3711	transcriptional antiterminator
MG974_RS18075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MG974_RS18085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MG974_RS18090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MG974_RS18100	COG0640	Transcriptional regulator
MG974_RS18105	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MG974_RS18110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MG974_RS18115	COG1447	Phosphotransferase system cellobiose-specific component IIA
MG974_RS18120	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MG974_RS18125	COG2723	6-phospho-beta-galactosidase activity
MG974_RS18130	COG1940	carbohydrate kinase activity
MG974_RS18135	COG1482	cell wall glycoprotein biosynthetic process
MG974_RS18145	COG0753	catalase activity
MG974_RS18150	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MG974_RS18155	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MG974_RS18160	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MG974_RS18165	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MG974_RS18170	COG4988	ABC transporter
MG974_RS18175	COG1294	oxidase, subunit
MG974_RS18180	COG1271	oxidase subunit
MG974_RS18185	COG3493	citrate carrier protein
MG974_RS18190	COG0726	polysaccharide deacetylase
MG974_RS18195	COG3842	ATPase activity
MG974_RS18200	COG2508	Transcriptional regulator
MG974_RS18205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MG974_RS18215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MG974_RS18230	COG4894	glucomannan catabolic process
MG974_RS18235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MG974_RS18240	COG0500	methyltransferase
MG974_RS18245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MG974_RS18260	COG0753	catalase activity
MG974_RS18260	COG0693	protein deglycase activity
MG974_RS18265	COG2851	Citrate transporter
MG974_RS18270	COG2273	Hydrolase Family 16
MG974_RS18280	COG2270	Major facilitator Superfamily
MG974_RS18285	COG0513	Belongs to the DEAD box helicase family
MG974_RS18375	COG0697	spore germination
MG974_RS18380	COG0589	response to stress
MG974_RS18390	COG0494	nUDIX hydrolase
MG974_RS18395	COG3507	Belongs to the glycosyl hydrolase 43 family
MG974_RS18420	COG0010	Belongs to the arginase family
MG974_RS18425	COG0833	amino acid
MG974_RS18430	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MG974_RS18435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MG974_RS18445	COG2390	Transcriptional regulator
MG974_RS18450	COG0561	phosphatase activity
MG974_RS18480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MG974_RS18485	COG5294	Protein conserved in bacteria
MG974_RS18490	COG0577	efflux transmembrane transporter activity
MG974_RS18495	COG1136	(ABC) transporter
MG974_RS18500	COG2205	protein histidine kinase activity
MG974_RS18505	COG0745	RESPONSE REGULATOR receiver
MG974_RS18520	COG1082	Xylose isomerase domain protein TIM barrel
MG974_RS18530	COG2814	Major facilitator Superfamily
MG974_RS18560	COG1349	DNA-binding transcription factor activity
MG974_RS18565	COG0667	Aldo Keto reductase
MG974_RS18570	COG2814	Major facilitator Superfamily
MG974_RS18585	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS18590	COG2197	response regulator
MG974_RS18595	COG4585	Histidine kinase
MG974_RS18600	COG3239	Fatty acid desaturase
MG974_RS18605	COG1309	transcriptional regulator
MG974_RS18610	COG1012	belongs to the aldehyde dehydrogenase family
MG974_RS18615	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MG974_RS18625	COG0640	Transcriptional regulator
MG974_RS18630	COG2814	Major facilitator Superfamily
MG974_RS18635	COG1714	RDD family
MG974_RS18650	COG0501	Belongs to the peptidase M48B family
MG974_RS18655	COG1715	Restriction endonuclease
MG974_RS18660	COG0450	alkyl hydroperoxide reductase
MG974_RS18665	COG3634	alkyl hydroperoxide reductase activity
MG974_RS18670	COG1113	amino acid transport
MG974_RS18680	COG2080	2 iron, 2 sulfur cluster binding
MG974_RS18695	COG2068	MobA-Related Protein
MG974_RS18700	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MG974_RS18745	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MG974_RS18750	COG0667	Aldo Keto reductase
MG974_RS18755	COG0456	acetyltransferase
MG974_RS18760	COG0457	Tetratricopeptide repeat
MG974_RS18765	COG0010	Belongs to the arginase family
MG974_RS18770	COG0833	amino acid
MG974_RS18775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MG974_RS18780	COG5658	integral membrane protein
MG974_RS18785	COG0640	Transcriptional regulator
MG974_RS18790	COG3829	transcription factor binding
MG974_RS18800	COG0488	(ABC) transporter
MG974_RS18815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MG974_RS18820	COG5002	protein histidine kinase activity
MG974_RS18830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MG974_RS18835	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MG974_RS18840	COG4853	Protein conserved in bacteria
MG974_RS18845	COG4863	YycH protein
MG974_RS18850	COG5002	protein histidine kinase activity
MG974_RS18855	COG0745	RESPONSE REGULATOR receiver
MG974_RS18885	COG0346	lactoylglutathione lyase activity
MG974_RS18890	COG0305	Participates in initiation and elongation during chromosome replication
MG974_RS18905	COG3093	addiction module antidote protein HigA
MG974_RS18910	COG0297	glycogen (starch) synthase activity
MG974_RS18920	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MG974_RS18925	COG0438	transferase activity, transferring glycosyl groups
MG974_RS18935	COG0515	serine threonine protein kinase
MG974_RS18945	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MG974_RS18950	COG4241	membrane
MG974_RS18960	COG5577	PFAM Coat F domain
MG974_RS18965	COG1733	regulation of RNA biosynthetic process
MG974_RS18975	COG0697	spore germination
MG974_RS18980	COG1621	beta-fructofuranosidase activity
MG974_RS18985	COG1621	beta-fructofuranosidase activity
MG974_RS18990	COG1802	Transcriptional regulator
MG974_RS18995	COG2318	DinB family
MG974_RS19000	COG2211	Major facilitator Superfamily
MG974_RS19010	COG0778	Nitroreductase
MG974_RS19015	COG1846	Transcriptional regulator
MG974_RS19020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MG974_RS19025	COG1846	Transcriptional regulator
MG974_RS19040	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MG974_RS19045	COG0583	DNA-binding transcription factor activity
MG974_RS19050	COG1028	Short-chain dehydrogenase reductase Sdr
MG974_RS19055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MG974_RS19060	COG0697	spore germination
MG974_RS19070	COG1959	2 iron, 2 sulfur cluster binding
MG974_RS19075	COG1396	sequence-specific DNA binding
MG974_RS19085	COG1331	Highly conserved protein containing a thioredoxin domain
MG974_RS19090	COG1266	CAAX protease self-immunity
MG974_RS19095	COG2814	Major facilitator Superfamily
MG974_RS19095	COG0477	Major facilitator Superfamily
MG974_RS19100	COG0346	lactoylglutathione lyase activity
MG974_RS19105	COG1609	Transcriptional regulator
MG974_RS19110	COG0708	Exodeoxyribonuclease III
MG974_RS19115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MG974_RS19120	COG2169	Transcriptional regulator
MG974_RS19130	COG0629	single-stranded DNA binding
MG974_RS19140	COG0012	GTP binding
MG974_RS19145	COG0243	molybdopterin cofactor binding
MG974_RS19150	COG4481	Protein conserved in bacteria
MG974_RS19155	COG3949	Membrane
MG974_RS19170	COG1475	DNA binding
MG974_RS19175	COG1192	Involved in chromosome partitioning
MG974_RS19200	COG1847	R3H domain protein
MG974_RS19205	COG0706	membrane insertase activity
MG974_RS19225	COG0457	Tetratricopeptide repeat