locus-tag	class	description
HNV93_RS00020	COG0656	L-ascorbic acid biosynthetic process
HNV93_RS00025	COG1733	regulation of RNA biosynthetic process
HNV93_RS00040	COG1794	racemase activity, acting on amino acids and derivatives
HNV93_RS00065	COG0398	Pfam SNARE associated Golgi protein
HNV93_RS00075	COG2755	lipolytic protein G-D-S-L family
HNV93_RS00085	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HNV93_RS00090	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HNV93_RS00095	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HNV93_RS00100	COG1534	Rna-binding protein
HNV93_RS00110	COG1713	HD superfamily hydrolase involved in NAD metabolism
HNV93_RS00115	COG0799	negative regulation of ribosome biogenesis
HNV93_RS00120	COG2226	methyltransferase
HNV93_RS00125	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HNV93_RS00130	COG1555	photosystem II stabilization
HNV93_RS00130	COG1596	polysaccharide export
HNV93_RS00135	COG2131	deaminase
HNV93_RS00140	COG2333	competence protein COMEC
HNV93_RS00140	COG0658	competence protein
HNV93_RS00155	COG1466	dna polymerase III delta subunit
HNV93_RS00170	COG0860	N-Acetylmuramoyl-L-alanine amidase
HNV93_RS00185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HNV93_RS00215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HNV93_RS00220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HNV93_RS00225	COG1283	sodium-dependent phosphate transmembrane transporter activity
HNV93_RS00235	COG1610	YqeY-like protein
HNV93_RS00240	COG1030	water channel activity
HNV93_RS00245	COG4864	UPF0365 protein
HNV93_RS00260	COG0561	phosphatase activity
HNV93_RS00265	COG1702	phosphate starvation-inducible protein PhoH
HNV93_RS00270	COG1480	7TM receptor with intracellular HD hydrolase
HNV93_RS00280	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HNV93_RS00285	COG0295	cytidine deaminase activity
HNV93_RS00290	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HNV93_RS00310	COG0751	glycine-tRNA ligase activity
HNV93_RS00315	COG0517	IMP dehydrogenase activity
HNV93_RS00330	COG0358	DNA primase activity
HNV93_RS00335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNV93_RS00340	COG2010	Cytochrome c
HNV93_RS00345	COG2384	SAM-dependent methyltransferase
HNV93_RS00350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HNV93_RS00365	COG0513	Belongs to the DEAD box helicase family
HNV93_RS00380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNV93_RS00385	COG0735	belongs to the Fur family
HNV93_RS00390	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
HNV93_RS00395	COG4709	membrane
HNV93_RS00405	COG1388	LysM domain
HNV93_RS00410	COG5521	maltodextrose utilization protein MalA
HNV93_RS00415	COG2839	Protein conserved in bacteria
HNV93_RS00420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HNV93_RS00425	COG0477	Major facilitator Superfamily
HNV93_RS00435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HNV93_RS00440	COG0573	inorganic phosphate transmembrane transporter activity
HNV93_RS00445	COG0581	inorganic phosphate transmembrane transporter activity
HNV93_RS00450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HNV93_RS00455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HNV93_RS00460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HNV93_RS00475	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HNV93_RS00485	COG1757	Na H antiporter
HNV93_RS00490	COG4483	Protein conserved in bacteria
HNV93_RS00495	COG1940	carbohydrate kinase activity
HNV93_RS00500	COG2866	Carboxypeptidase
HNV93_RS00510	COG0011	TIGRFAM Protein of
HNV93_RS00520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNV93_RS00530	COG1393	Belongs to the ArsC family
HNV93_RS00540	COG1366	Belongs to the anti-sigma-factor antagonist family
HNV93_RS00545	COG1253	flavin adenine dinucleotide binding
HNV93_RS00550	COG0598	Magnesium transport protein CorA
HNV93_RS00555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HNV93_RS00560	COG1459	type II secretion system
HNV93_RS00565	COG4537	Required for transformation and DNA binding
HNV93_RS00570	COG4970	Tfp pilus assembly protein FimT
HNV93_RS00580	COG4940	Competence protein ComGF
HNV93_RS00605	COG0681	Belongs to the peptidase S26 family
HNV93_RS00615	COG1396	sequence-specific DNA binding
HNV93_RS00630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HNV93_RS00650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNV93_RS00665	COG1752	Esterase of the alpha-beta hydrolase superfamily
HNV93_RS00675	COG3872	metal-dependent enzyme
HNV93_RS00685	COG0006	proline dipeptidase activity
HNV93_RS00700	COG3854	ATPases associated with a variety of cellular activities
HNV93_RS00740	COG0511	ligase activity, forming carbon-carbon bonds
HNV93_RS00745	COG0439	Biotin carboxylase
HNV93_RS00750	COG1302	Protein conserved in bacteria
HNV93_RS00765	COG1570	exodeoxyribonuclease VII activity
HNV93_RS00775	COG0142	geranyltranstransferase activity
HNV93_RS00785	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HNV93_RS00795	COG0497	DNA recombination
HNV93_RS00800	COG0750	zinc metalloprotease
HNV93_RS00805	COG0745	RESPONSE REGULATOR receiver
HNV93_RS00810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HNV93_RS00825	COG1902	pentaerythritol trinitrate reductase activity
HNV93_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
HNV93_RS00855	COG0584	glycerophosphoryl diester phosphodiesterase
HNV93_RS00860	COG0183	Belongs to the thiolase family
HNV93_RS00865	COG1250	3-hydroxyacyl-CoA dehydrogenase
HNV93_RS00870	COG1960	acyl-CoA dehydrogenase activity
HNV93_RS00875	COG0372	Belongs to the citrate synthase family
HNV93_RS00880	COG2079	MmgE PrpD family protein
HNV93_RS00885	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HNV93_RS00895	COG3290	protein histidine kinase activity
HNV93_RS00895	COG3829	transcription factor binding
HNV93_RS00900	COG0280	phosphate acetyltransferase
HNV93_RS00905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HNV93_RS00910	COG3426	butyrate kinase activity
HNV93_RS00915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HNV93_RS00920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HNV93_RS00925	COG0022	dehydrogenase e1 component
HNV93_RS00930	COG0508	dehydrogenase complex catalyzes the overall conversion of
HNV93_RS00935	COG1597	lipid kinase activity
HNV93_RS00945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNV93_RS00950	COG0765	amino acid transport
HNV93_RS00955	COG1126	abc transporter atp-binding protein
HNV93_RS00960	COG4129	membrane
HNV93_RS00975	COG0346	lactoylglutathione lyase activity
HNV93_RS00980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HNV93_RS00985	COG2195	Cleaves the N-terminal amino acid of tripeptides
HNV93_RS00990	COG0706	membrane insertase activity
HNV93_RS01005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HNV93_RS01010	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HNV93_RS01025	COG0596	Alpha beta hydrolase
HNV93_RS01045	COG0250	Participates in transcription elongation, termination and antitermination
HNV93_RS01050	COG2070	2-Nitropropane dioxygenase
HNV93_RS01050	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HNV93_RS01065	COG0318	PFAM AMP-dependent synthetase and ligase
HNV93_RS01070	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS01075	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS01075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNV93_RS01075	COG3321	synthase
HNV93_RS01075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNV93_RS01075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS01085	COG3321	synthase
HNV93_RS01085	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS01085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS01085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNV93_RS01085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNV93_RS01090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS01090	COG0300	oxidoreductase activity
HNV93_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS01090	COG0318	PFAM AMP-dependent synthetase and ligase
HNV93_RS01090	COG3321	synthase
HNV93_RS01095	COG0318	PFAM AMP-dependent synthetase and ligase
HNV93_RS01095	COG0300	oxidoreductase activity
HNV93_RS01095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS01095	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS01095	COG3321	synthase
HNV93_RS01100	COG3321	synthase
HNV93_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS01100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS01100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNV93_RS01100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNV93_RS01105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNV93_RS01105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNV93_RS01105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS01105	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS01105	COG3321	synthase
HNV93_RS01110	COG2124	cytochrome p450
HNV93_RS01115	COG3425	synthase
HNV93_RS01120	COG1024	Enoyl-CoA hydratase
HNV93_RS01125	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HNV93_RS01130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNV93_RS01135	COG0300	oxidoreductase activity
HNV93_RS01140	COG3048	D-serine ammonia-lyase activity
HNV93_RS01150	COG0346	lactoylglutathione lyase activity
HNV93_RS01160	COG0628	permease
HNV93_RS01175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNV93_RS01180	COG0456	acetyltransferase
HNV93_RS01185	COG2329	Antibiotic biosynthesis monooxygenase
HNV93_RS01190	COG0456	acetyltransferase
HNV93_RS01190	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HNV93_RS01195	COG4918	Iron-sulphur cluster biosynthesis
HNV93_RS01205	COG1073	alpha beta
HNV93_RS01215	COG0667	Aldo Keto reductase
HNV93_RS01225	COG0494	nUDIX hydrolase
HNV93_RS01230	COG1379	DNA repair
HNV93_RS01235	COG1396	sequence-specific DNA binding
HNV93_RS01240	COG0252	asparaginase activity
HNV93_RS01245	COG1027	Aspartate ammonia-lyase
HNV93_RS01250	COG1757	Na H antiporter
HNV93_RS01255	COG0281	malic enzyme
HNV93_RS01270	COG1300	Membrane
HNV93_RS01275	COG0735	belongs to the Fur family
HNV93_RS01285	COG4974	Belongs to the 'phage' integrase family
HNV93_RS01290	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HNV93_RS01295	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HNV93_RS01300	COG1686	Belongs to the peptidase S11 family
HNV93_RS01305	COG1366	Belongs to the anti-sigma-factor antagonist family
HNV93_RS01315	COG1191	sigma factor activity
HNV93_RS01335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HNV93_RS01350	COG0697	spore germination
HNV93_RS01355	COG0019	diaminopimelate decarboxylase activity
HNV93_RS01360	COG4086	secreted protein
HNV93_RS01365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HNV93_RS01375	COG0681	Belongs to the peptidase S26 family
HNV93_RS01385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HNV93_RS01385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HNV93_RS01390	COG0307	riboflavin synthase, alpha
HNV93_RS01405	COG0456	acetyltransferase
HNV93_RS01410	COG1547	Domain of unknown function (DUF309)
HNV93_RS01435	COG1686	Belongs to the peptidase S11 family
HNV93_RS01440	COG2715	membrane protein required for spore maturation
HNV93_RS01445	COG0700	Nucleoside recognition
HNV93_RS01450	COG1187	pseudouridine synthase activity
HNV93_RS01455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNV93_RS01460	COG1333	cytochrome c biogenesis protein
HNV93_RS01465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HNV93_RS01470	COG0745	RESPONSE REGULATOR receiver
HNV93_RS01475	COG5002	protein histidine kinase activity
HNV93_RS01480	COG1595	DNA-templated transcription, initiation
HNV93_RS01490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HNV93_RS01495	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HNV93_RS01500	COG1141	Ferredoxin
HNV93_RS01505	COG4955	Helix-turn-helix domain
HNV93_RS01515	COG1266	CAAX protease self-immunity
HNV93_RS01520	COG1388	LysM domain
HNV93_RS01530	COG1408	metallophosphoesterase
HNV93_RS01535	COG4862	establishment of competence for transformation
HNV93_RS01540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HNV93_RS01545	COG0492	ferredoxin-NADP+ reductase activity
HNV93_RS01550	COG2339	peptidase activity
HNV93_RS01555	COG3773	Cell wall hydrolase
HNV93_RS01555	COG3409	Peptidoglycan-binding domain 1 protein
HNV93_RS01560	COG2959	enzyme of heme biosynthesis
HNV93_RS01565	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HNV93_RS01580	COG0539	negative regulation of cytoplasmic translation
HNV93_RS01620	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HNV93_RS01625	COG0776	regulation of translation
HNV93_RS01640	COG0142	geranyltranstransferase activity
HNV93_RS01650	COG0142	geranyltranstransferase activity
HNV93_RS01655	COG0105	UTP biosynthetic process
HNV93_RS01660	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HNV93_RS01675	COG4401	Chorismate mutase type I
HNV93_RS01680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HNV93_RS01715	COG0287	Prephenate dehydrogenase
HNV93_RS01725	COG0457	Tetratricopeptide repeat
HNV93_RS01740	COG0723	plastoquinol--plastocyanin reductase activity
HNV93_RS01745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HNV93_RS01750	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HNV93_RS01750	COG2010	Cytochrome c
HNV93_RS01755	COG4347	Protein of unknown function (DUF1405)
HNV93_RS01770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNV93_RS01775	COG1694	Mazg nucleotide pyrophosphohydrolase
HNV93_RS01790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HNV93_RS01795	COG0438	transferase activity, transferring glycosyl groups
HNV93_RS01825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HNV93_RS01825	COG1199	ATP-dependent helicase activity
HNV93_RS01835	COG5353	protein conserved in bacteria
HNV93_RS01840	COG0436	Aminotransferase
HNV93_RS01850	COG3935	DnaD domain protein
HNV93_RS01855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HNV93_RS01865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HNV93_RS01865	COG4499	WXG100 protein secretion system (Wss), protein YukC
HNV93_RS01905	COG0071	Belongs to the small heat shock protein (HSP20) family
HNV93_RS01910	COG2190	(PTS) system
HNV93_RS01915	COG1111	helicase
HNV93_RS01915	COG1205	dead DEAH box helicase
HNV93_RS01920	COG3359	exonuclease
HNV93_RS01950	COG0116	Belongs to the methyltransferase superfamily
HNV93_RS01965	COG1199	ATP-dependent helicase activity
HNV93_RS01970	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HNV93_RS01980	COG2233	PERMEase
HNV93_RS01990	COG1335	isochorismatase
HNV93_RS02010	COG3424	synthase
HNV93_RS02015	COG1755	Isoprenylcysteine carboxyl methyltransferase
HNV93_RS02025	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HNV93_RS02040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HNV93_RS02050	COG0328	RNA-DNA hybrid ribonuclease activity
HNV93_RS02055	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HNV93_RS02060	COG0328	RNA-DNA hybrid ribonuclease activity
HNV93_RS02080	COG1278	Cold shock
HNV93_RS02090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HNV93_RS02100	COG0386	Belongs to the glutathione peroxidase family
HNV93_RS02105	COG1418	mRNA catabolic process
HNV93_RS02110	COG1413	lyase activity
HNV93_RS02125	COG2136	Putative SAM-dependent methyltransferase
HNV93_RS02125	COG2521	methyltransferase
HNV93_RS02140	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HNV93_RS02145	COG0204	Acyl-transferase
HNV93_RS02150	COG1272	protein, Hemolysin III
HNV93_RS02155	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HNV93_RS02160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HNV93_RS02170	COG1999	signal sequence binding
HNV93_RS02175	COG2755	lipolytic protein G-D-S-L family
HNV93_RS02180	COG4698	Protein conserved in bacteria
HNV93_RS02185	COG1846	Transcriptional regulator
HNV93_RS02205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HNV93_RS02210	COG1525	nuclease
HNV93_RS02215	COG4282	regulation of fungal-type cell wall biogenesis
HNV93_RS02220	COG5444	nuclease activity
HNV93_RS02240	COG3391	amine dehydrogenase activity
HNV93_RS02250	COG0457	Tetratricopeptide repeat
HNV93_RS02285	COG1086	Polysaccharide biosynthesis protein
HNV93_RS02295	COG4641	Protein conserved in bacteria
HNV93_RS02310	COG0463	Glycosyl transferase, family 2
HNV93_RS02315	COG0456	acetyltransferase
HNV93_RS02325	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HNV93_RS02330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HNV93_RS02335	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HNV93_RS02340	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HNV93_RS02345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HNV93_RS02350	COG0456	acetyltransferase
HNV93_RS02355	COG1509	lysine 2,3-aminomutase activity
HNV93_RS02385	COG0671	phosphoesterase, PA-phosphatase related
HNV93_RS02405	COG1876	peptidase activity
HNV93_RS02415	COG2226	methyltransferase
HNV93_RS02420	COG0793	Belongs to the peptidase S41A family
HNV93_RS02420	COG3409	Peptidoglycan-binding domain 1 protein
HNV93_RS02425	COG2188	Transcriptional regulator
HNV93_RS02430	COG2723	6-phospho-beta-galactosidase activity
HNV93_RS02440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNV93_RS02450	COG0346	lactoylglutathione lyase activity
HNV93_RS02455	COG0400	carboxylic ester hydrolase activity
HNV93_RS02460	COG0778	Nitroreductase
HNV93_RS02465	COG1733	regulation of RNA biosynthetic process
HNV93_RS02475	COG1942	4-Oxalocrotonate Tautomerase
HNV93_RS02490	COG2962	Rard protein
HNV93_RS02500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HNV93_RS02505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HNV93_RS02510	COG1366	Belongs to the anti-sigma-factor antagonist family
HNV93_RS02515	COG0534	Mate efflux family protein
HNV93_RS02520	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HNV93_RS02525	COG1819	glycosyl
HNV93_RS02530	COG1388	LysM domain
HNV93_RS02530	COG0791	NLP P60 protein
HNV93_RS02535	COG2032	superoxide dismutase activity
HNV93_RS02540	COG0714	Associated with various cellular activities
HNV93_RS02545	COG4548	von Willebrand factor, type A
HNV93_RS02555	COG0508	dehydrogenase complex catalyzes the overall conversion of
HNV93_RS02560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNV93_RS02565	COG0385	Bile acid
HNV93_RS02570	COG0733	neurotransmitter:sodium symporter activity
HNV93_RS02575	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HNV93_RS02580	COG1657	PFAM Prenyltransferase squalene oxidase
HNV93_RS02585	COG1012	belongs to the aldehyde dehydrogenase family
HNV93_RS02615	COG0071	Belongs to the small heat shock protein (HSP20) family
HNV93_RS02630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HNV93_RS02635	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HNV93_RS02645	COG0514	ATP-dependent DNA helicase (RecQ)
HNV93_RS02650	COG3584	3D domain protein
HNV93_RS02650	COG1388	LysM domain
HNV93_RS02660	COG1619	proteins homologs of microcin C7 resistance protein MccF
HNV93_RS02675	COG2322	membrane
HNV93_RS02680	COG0741	lytic transglycosylase activity
HNV93_RS02685	COG0640	Transcriptional regulator
HNV93_RS02695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNV93_RS02700	COG1309	transcriptional regulator
HNV93_RS02705	COG2207	Transcriptional regulator
HNV93_RS02705	COG0662	Cupin 2, conserved barrel domain protein
HNV93_RS02710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNV93_RS02715	COG5444	nuclease activity
HNV93_RS02745	COG0243	molybdopterin cofactor binding
HNV93_RS02750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HNV93_RS02755	COG1070	Carbohydrate kinase
HNV93_RS02760	COG2814	Major facilitator Superfamily
HNV93_RS02770	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HNV93_RS02775	COG0300	oxidoreductase activity
HNV93_RS02790	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HNV93_RS02795	COG0583	DNA-binding transcription factor activity
HNV93_RS02800	COG0069	glutamate synthase activity
HNV93_RS02800	COG0067	glutamate synthase
HNV93_RS02800	COG0070	glutamate synthase
HNV93_RS02805	COG0493	'glutamate synthase
HNV93_RS02810	COG0604	alcohol dehydrogenase
HNV93_RS02820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HNV93_RS02825	COG0640	Transcriptional regulator
HNV93_RS02830	COG2814	Major facilitator Superfamily
HNV93_RS02835	COG0405	Gamma-glutamyltransferase
HNV93_RS02840	COG0166	Belongs to the GPI family
HNV93_RS02845	COG0582	viral genome integration into host DNA
HNV93_RS02860	COG0534	Mate efflux family protein
HNV93_RS02865	COG2017	converts alpha-aldose to the beta-anomer
HNV93_RS02870	COG2027	D-alanyl-D-alanine carboxypeptidase
HNV93_RS02875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS02880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS02885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS02890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS02895	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HNV93_RS02895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS02905	COG1649	PFAM Uncharacterised BCR, COG1649
HNV93_RS02910	COG1960	acyl-CoA dehydrogenase activity
HNV93_RS02915	COG0318	PFAM AMP-dependent synthetase and ligase
HNV93_RS02920	COG0439	Biotin carboxylase
HNV93_RS02925	COG0511	ligase activity, forming carbon-carbon bonds
HNV93_RS02930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HNV93_RS02935	COG1024	Enoyl-CoA hydratase
HNV93_RS02940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HNV93_RS02945	COG0586	Pfam SNARE associated Golgi protein
HNV93_RS02955	COG2246	polysaccharide biosynthetic process
HNV93_RS02965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HNV93_RS02985	COG2124	cytochrome p450
HNV93_RS02990	COG2610	gluconate transmembrane transporter activity
HNV93_RS02995	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HNV93_RS03000	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HNV93_RS03005	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS03030	COG3507	Belongs to the glycosyl hydrolase 43 family
HNV93_RS03040	COG0745	RESPONSE REGULATOR receiver
HNV93_RS03045	COG2205	protein histidine kinase activity
HNV93_RS03090	COG2271	Major facilitator Superfamily
HNV93_RS03095	COG1609	Transcriptional regulator
HNV93_RS03100	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS03105	COG1312	Catalyzes the dehydration of D-mannonate
HNV93_RS03110	COG0800	Aldolase
HNV93_RS03115	COG1063	alcohol dehydrogenase
HNV93_RS03125	COG1115	amino acid carrier protein
HNV93_RS03135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNV93_RS03140	COG0187	DNA topoisomerase II activity
HNV93_RS03145	COG1832	CoA-binding protein
HNV93_RS03155	COG4841	protein insertion into membrane
HNV93_RS03165	COG0824	Thioesterase
HNV93_RS03185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNV93_RS03190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HNV93_RS03205	COG0071	Belongs to the small heat shock protein (HSP20) family
HNV93_RS03215	COG4846	Membrane protein involved in cytochrome C biogenesis
HNV93_RS03220	COG2201	protein-glutamate methylesterase activity
HNV93_RS03225	COG0785	Cytochrome C biogenesis protein
HNV93_RS03245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HNV93_RS03255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HNV93_RS03290	COG4195	phage-related replication protein
HNV93_RS03295	COG0756	dUTP diphosphatase activity
HNV93_RS03300	COG5434	Belongs to the glycosyl hydrolase 28 family
HNV93_RS03320	COG3397	chitin binding
HNV93_RS03360	COG4451	ribulose bisphosphate carboxylase, small
HNV93_RS03360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HNV93_RS03365	COG1064	alcohol dehydrogenase
HNV93_RS03390	COG3848	Pyruvate phosphate dikinase
HNV93_RS03390	COG0574	Belongs to the PEP-utilizing enzyme family
HNV93_RS03395	COG1070	Carbohydrate kinase
HNV93_RS03410	COG3507	Belongs to the glycosyl hydrolase 43 family
HNV93_RS03415	COG2211	Major facilitator Superfamily
HNV93_RS03455	COG0174	glutamine synthetase
HNV93_RS03460	COG0789	Transcriptional regulator
HNV93_RS03465	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HNV93_RS03470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HNV93_RS03475	COG0464	growth
HNV93_RS03480	COG0860	N-Acetylmuramoyl-L-alanine amidase
HNV93_RS03485	COG4112	unkown
HNV93_RS03490	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNV93_RS03495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNV93_RS03535	COG2076	Multidrug Resistance protein
HNV93_RS03545	COG1764	response to oxidative stress
HNV93_RS03550	COG4195	phage-related replication protein
HNV93_RS03560	COG1404	Belongs to the peptidase S8 family
HNV93_RS03570	COG3619	membrane
HNV93_RS03575	COG3209	COG3209 Rhs family protein
HNV93_RS03580	COG2124	cytochrome p450
HNV93_RS03585	COG3321	synthase
HNV93_RS03585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNV93_RS03585	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HNV93_RS03585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HNV93_RS03590	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS03590	COG3321	synthase
HNV93_RS03590	COG4221	oxidoreductase activity
HNV93_RS03590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS03595	COG3321	synthase
HNV93_RS03595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNV93_RS03595	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS03595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS03595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNV93_RS03595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNV93_RS03595	COG3321	synthase
HNV93_RS03595	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS03595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS03595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNV93_RS03600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNV93_RS03600	COG3321	synthase
HNV93_RS03600	COG0300	oxidoreductase activity
HNV93_RS03600	COG4221	oxidoreductase activity
HNV93_RS03605	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS03605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS03605	COG3321	synthase
HNV93_RS03605	COG0318	PFAM AMP-dependent synthetase and ligase
HNV93_RS03605	COG0300	oxidoreductase activity
HNV93_RS03610	COG1024	Enoyl-CoA hydratase
HNV93_RS03615	COG1024	Enoyl-CoA hydratase
HNV93_RS03620	COG3425	synthase
HNV93_RS03625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNV93_RS03670	COG4550	Control of competence regulator ComK, YlbF/YmcA
HNV93_RS03690	COG2359	stage V sporulation protein S
HNV93_RS03695	COG1692	metallophosphoesterase
HNV93_RS03705	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HNV93_RS03720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HNV93_RS03725	COG1426	Protein conserved in bacteria
HNV93_RS03740	COG0300	oxidoreductase activity
HNV93_RS03745	COG0612	Peptidase, M16
HNV93_RS03750	COG0612	Peptidase, M16
HNV93_RS03755	COG1033	growth of symbiont in host cell
HNV93_RS03755	COG2409	Drug exporters of the RND superfamily
HNV93_RS03760	COG1846	Transcriptional regulator
HNV93_RS03765	COG2814	Major facilitator Superfamily
HNV93_RS03770	COG2188	Transcriptional regulator
HNV93_RS03775	COG4980	gas vesicle protein
HNV93_RS03775	COG1674	ftsk spoiiie
HNV93_RS03785	COG0740	serine-type endopeptidase activity
HNV93_RS03790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNV93_RS03800	COG0527	aspartate kinase activity
HNV93_RS03805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HNV93_RS03810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HNV93_RS03815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNV93_RS03820	COG1873	PFAM PRC-barrel domain
HNV93_RS03825	COG0612	Peptidase, M16
HNV93_RS03830	COG0726	polysaccharide deacetylase
HNV93_RS03845	COG0196	riboflavin kinase activity
HNV93_RS03860	COG1550	Protein conserved in bacteria
HNV93_RS03870	COG1358	cellular component organization or biogenesis
HNV93_RS03875	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HNV93_RS03880	COG0195	Participates in both transcription termination and antitermination
HNV93_RS03890	COG2176	DNA-directed DNA polymerase activity
HNV93_RS03900	COG0750	zinc metalloprotease
HNV93_RS03910	COG4589	Belongs to the CDS family
HNV93_RS03915	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HNV93_RS03945	COG1191	sigma factor activity
HNV93_RS03955	COG1776	CheC inhibitor of MCP methylation
HNV93_RS03960	COG0835	chemotaxis
HNV93_RS03965	COG0643	Histidine kinase
HNV93_RS03965	COG2198	Histidine kinase
HNV93_RS03970	COG2201	protein-glutamate methylesterase activity
HNV93_RS03975	COG0455	bacterial-type flagellum organization
HNV93_RS03980	COG1419	protein localization to endoplasmic reticulum
HNV93_RS03985	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HNV93_RS03990	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HNV93_RS03995	COG1684	flagellar biosynthetic protein fliR
HNV93_RS04000	COG1987	bacterial-type flagellum assembly
HNV93_RS04005	COG1338	Plays a role in the flagellum-specific transport system
HNV93_RS04010	COG3190	flagellar
HNV93_RS04015	COG2201	protein-glutamate methylesterase activity
HNV93_RS04020	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HNV93_RS04020	COG1776	CheC inhibitor of MCP methylation
HNV93_RS04025	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HNV93_RS04030	COG1580	Controls the rotational direction of flagella during chemotaxis
HNV93_RS04035	COG1582	Flagellar protein (FlbD)
HNV93_RS04040	COG4786	Flagellar basal body rod
HNV93_RS04045	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HNV93_RS04050	COG3144	bacterial-type flagellum assembly
HNV93_RS04055	COG3334	PFAM MgtE intracellular
HNV93_RS04060	COG2882	bacterial-type flagellum organization
HNV93_RS04065	COG1157	protein secretion by the type III secretion system
HNV93_RS04070	COG1317	bacterial-type flagellum organization
HNV93_RS04075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HNV93_RS04080	COG1766	The M ring may be actively involved in energy transduction
HNV93_RS04085	COG1677	Flagellar hook-basal body complex protein FliE
HNV93_RS04090	COG1558	bacterial-type flagellum-dependent cell motility
HNV93_RS04095	COG1815	bacterial-type flagellum-dependent cell motility
HNV93_RS04115	COG4974	Belongs to the 'phage' integrase family
HNV93_RS04125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HNV93_RS04130	COG0758	DNA mediated transformation
HNV93_RS04135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HNV93_RS04145	COG2257	FlhB HrpN YscU SpaS Family
HNV93_RS04160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HNV93_RS04185	COG1837	Belongs to the UPF0109 family
HNV93_RS04195	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HNV93_RS04210	COG0552	protein localization to endoplasmic reticulum
HNV93_RS04215	COG1196	nuclear chromosome segregation
HNV93_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS04235	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HNV93_RS04250	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HNV93_RS04255	COG1760	l-serine dehydratase
HNV93_RS04260	COG1760	l-serine dehydratase
HNV93_RS04265	COG1461	Dihydroxyacetone kinase
HNV93_RS04270	COG1302	Protein conserved in bacteria
HNV93_RS04285	COG1564	THIamine pyrophosphokinase
HNV93_RS04290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HNV93_RS04300	COG2815	serine threonine protein kinase
HNV93_RS04300	COG0515	serine threonine protein kinase
HNV93_RS04305	COG0631	protein serine/threonine phosphatase activity
HNV93_RS04315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HNV93_RS04315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HNV93_RS04325	COG0242	peptide deformylase activity
HNV93_RS04330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HNV93_RS04335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HNV93_RS04345	COG0194	GDP metabolic process
HNV93_RS04355	COG1561	YicC-like family, N-terminal region
HNV93_RS04360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HNV93_RS04370	COG1648	precorrin-2 dehydrogenase activity
HNV93_RS04375	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
HNV93_RS04380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HNV93_RS04395	COG0306	phosphate transporter
HNV93_RS04405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HNV93_RS04410	COG0284	orotidine-5'-phosphate decarboxylase activity
HNV93_RS04425	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HNV93_RS04430	COG0505	Belongs to the CarA family
HNV93_RS04435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HNV93_RS04445	COG2233	PERMEase
HNV93_RS04455	COG0564	pseudouridine synthase activity
HNV93_RS04465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HNV93_RS04470	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HNV93_RS04475	COG3599	regulation of cell shape
HNV93_RS04480	COG2302	S4 RNA-binding domain
HNV93_RS04485	COG0762	integral membrane protein
HNV93_RS04495	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HNV93_RS04505	COG1873	PFAM PRC-barrel domain
HNV93_RS04510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HNV93_RS04515	COG1119	ATPase activity
HNV93_RS04520	COG1191	sigma factor activity
HNV93_RS04525	COG1191	sigma factor activity
HNV93_RS04535	COG4412	M6 family metalloprotease domain protein
HNV93_RS04535	COG1404	Belongs to the peptidase S8 family
HNV93_RS04540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HNV93_RS04545	COG0849	cell division
HNV93_RS04550	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HNV93_RS04565	COG0772	Belongs to the SEDS family
HNV93_RS04585	COG0768	penicillin binding
HNV93_RS04595	COG4839	cell division protein FtsL
HNV93_RS04615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HNV93_RS04635	COG1399	metal-binding, possibly nucleic acid-binding protein
HNV93_RS04645	COG3480	Lon protease (S16) C-terminal proteolytic domain
HNV93_RS04650	COG1752	Esterase of the alpha-beta hydrolase superfamily
HNV93_RS04655	COG3314	Sporulation integral membrane protein YlbJ
HNV93_RS04665	COG0742	ribosomal rna small subunit methyltransferase
HNV93_RS04675	COG3679	Belongs to the UPF0342 family
HNV93_RS04690	COG2340	Cysteine-rich secretory protein family
HNV93_RS04695	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HNV93_RS04705	COG3336	cytochrome c oxidase
HNV93_RS04710	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HNV93_RS04715	COG1845	cytochrome c oxidase, subunit III
HNV93_RS04720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HNV93_RS04725	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HNV93_RS04725	COG2010	Cytochrome c
HNV93_RS04740	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HNV93_RS04745	COG0772	Belongs to the SEDS family
HNV93_RS04755	COG2066	Belongs to the glutaminase family
HNV93_RS04760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HNV93_RS04765	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HNV93_RS04775	COG4896	Protein conserved in bacteria
HNV93_RS04810	COG3227	Zinc metalloprotease (Elastase)
HNV93_RS04820	COG0483	inositol monophosphate 1-phosphatase activity
HNV93_RS04840	COG1982	Orn Lys Arg decarboxylase major
HNV93_RS04855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNV93_RS04860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HNV93_RS04865	COG0508	dehydrogenase complex catalyzes the overall conversion of
HNV93_RS04870	COG0022	dehydrogenase e1 component
HNV93_RS04875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HNV93_RS04880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HNV93_RS04885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS04885	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS04885	COG3321	synthase
HNV93_RS04885	COG4221	oxidoreductase activity
HNV93_RS04890	COG3321	synthase
HNV93_RS04890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNV93_RS04890	COG0300	oxidoreductase activity
HNV93_RS04890	COG4221	oxidoreductase activity
HNV93_RS04895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNV93_RS04895	COG0300	oxidoreductase activity
HNV93_RS04895	COG3321	synthase
HNV93_RS04895	COG4221	oxidoreductase activity
HNV93_RS04900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNV93_RS04900	COG0300	oxidoreductase activity
HNV93_RS04900	COG3321	synthase
HNV93_RS04900	COG4221	oxidoreductase activity
HNV93_RS04905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS04905	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS04905	COG3321	synthase
HNV93_RS04905	COG4221	oxidoreductase activity
HNV93_RS04910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNV93_RS04910	COG0300	oxidoreductase activity
HNV93_RS04910	COG3321	synthase
HNV93_RS04910	COG4221	oxidoreductase activity
HNV93_RS04915	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS04915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS04915	COG3321	synthase
HNV93_RS04915	COG4221	oxidoreductase activity
HNV93_RS04920	COG2070	2-Nitropropane dioxygenase
HNV93_RS04920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HNV93_RS04925	COG0497	DNA recombination
HNV93_RS04935	COG0242	peptide deformylase activity
HNV93_RS04940	COG0561	phosphatase activity
HNV93_RS04950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNV93_RS04960	COG0569	domain protein
HNV93_RS04965	COG2105	PFAM AIG2 family protein
HNV93_RS04965	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HNV93_RS04970	COG3852	Histidine kinase
HNV93_RS04975	COG2002	toxin-antitoxin pair type II binding
HNV93_RS04980	COG1077	Cell shape determining protein MreB Mrl
HNV93_RS04990	COG2309	aminopeptidase activity
HNV93_RS04995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HNV93_RS05000	COG0488	(ABC) transporter
HNV93_RS05010	COG0681	Belongs to the peptidase S26 family
HNV93_RS05015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNV93_RS05015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HNV93_RS05015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HNV93_RS05020	COG1105	Belongs to the carbohydrate kinase PfkB family
HNV93_RS05025	COG1349	DNA-binding transcription factor activity
HNV93_RS05030	COG0577	efflux transmembrane transporter activity
HNV93_RS05035	COG1136	(ABC) transporter
HNV93_RS05040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HNV93_RS05050	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HNV93_RS05055	COG0314	molybdopterin synthase activity
HNV93_RS05060	COG1763	Mo-molybdopterin cofactor biosynthetic process
HNV93_RS05065	COG0303	'Molybdopterin
HNV93_RS05070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HNV93_RS05090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNV93_RS05095	COG0668	transmembrane transport
HNV93_RS05115	COG0716	FMN binding
HNV93_RS05125	COG0716	FMN binding
HNV93_RS05130	COG0583	DNA-binding transcription factor activity
HNV93_RS05135	COG0517	IMP dehydrogenase activity
HNV93_RS05145	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
HNV93_RS05150	COG4703	Protein of unknown function (DUF1797)
HNV93_RS05155	COG2200	EAL domain
HNV93_RS05165	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS05170	COG1408	metallophosphoesterase
HNV93_RS05175	COG1376	ErfK ybiS ycfS ynhG family protein
HNV93_RS05180	COG2814	Major facilitator Superfamily
HNV93_RS05190	COG0784	Response regulator, receiver
HNV93_RS05190	COG0835	chemotaxis
HNV93_RS05200	COG0436	Aminotransferase
HNV93_RS05205	COG4191	Histidine kinase
HNV93_RS05210	COG0768	penicillin binding
HNV93_RS05215	COG2340	Cysteine-rich secretory protein family
HNV93_RS05220	COG2084	Dehydrogenase
HNV93_RS05225	COG0840	transmembrane signaling receptor activity
HNV93_RS05230	COG1533	DNA photolyase activity
HNV93_RS05240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HNV93_RS05245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNV93_RS05250	COG2190	(PTS) system
HNV93_RS05250	COG1263	PTS System
HNV93_RS05250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HNV93_RS05255	COG3711	transcriptional antiterminator
HNV93_RS05260	COG1609	Transcriptional regulator
HNV93_RS05265	COG0006	proline dipeptidase activity
HNV93_RS05270	COG2217	Heavy metal translocating P-type atpase
HNV93_RS05275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNV93_RS05280	COG2244	polysaccharide biosynthetic process
HNV93_RS05285	COG3773	Cell wall hydrolase
HNV93_RS05295	COG4873	Protein conserved in bacteria
HNV93_RS05310	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS05315	COG1733	regulation of RNA biosynthetic process
HNV93_RS05330	COG0602	queuosine metabolic process
HNV93_RS05335	COG0720	synthase
HNV93_RS05350	COG3949	Membrane
HNV93_RS05355	COG0542	response to heat
HNV93_RS05360	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HNV93_RS05365	COG1360	Flagellar Motor Protein
HNV93_RS05370	COG1846	Transcriptional regulator
HNV93_RS05375	COG3852	Histidine kinase
HNV93_RS05405	COG0436	Aminotransferase
HNV93_RS05410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HNV93_RS05425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HNV93_RS05430	COG5002	protein histidine kinase activity
HNV93_RS05435	COG3594	Acyltransferase
HNV93_RS05445	COG2323	membrane
HNV93_RS05450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HNV93_RS05475	COG1191	sigma factor activity
HNV93_RS05480	COG0861	Integral membrane protein TerC family
HNV93_RS05485	COG0586	Pfam SNARE associated Golgi protein
HNV93_RS05490	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HNV93_RS05495	COG3285	dna ligase
HNV93_RS05495	COG1793	dna ligase
HNV93_RS05500	COG0726	polysaccharide deacetylase
HNV93_RS05505	COG1846	Transcriptional regulator
HNV93_RS05520	COG0789	Transcriptional regulator
HNV93_RS05525	COG2239	Acts as a magnesium transporter
HNV93_RS05535	COG3858	chitin binding
HNV93_RS05535	COG1388	LysM domain
HNV93_RS05540	COG4721	ABC-type cobalt transport system, permease component
HNV93_RS05545	COG1122	ATPase activity
HNV93_RS05550	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNV93_RS05555	COG1366	Belongs to the anti-sigma-factor antagonist family
HNV93_RS05560	COG1404	Belongs to the peptidase S8 family
HNV93_RS05580	COG0457	Tetratricopeptide repeat
HNV93_RS05580	COG0463	Glycosyl transferase, family 2
HNV93_RS05595	COG1764	response to oxidative stress
HNV93_RS05600	COG1846	Transcriptional regulator
HNV93_RS05605	COG1764	response to oxidative stress
HNV93_RS05615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HNV93_RS05620	COG0788	formyltetrahydrofolate deformylase activity
HNV93_RS05625	COG2076	Multidrug Resistance protein
HNV93_RS05630	COG2076	Multidrug Resistance protein
HNV93_RS05635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HNV93_RS05640	COG1607	acyl-coa hydrolase
HNV93_RS05645	COG1834	amidinotransferase
HNV93_RS05650	COG2706	6-phosphogluconolactonase activity
HNV93_RS05655	COG4608	Belongs to the ABC transporter superfamily
HNV93_RS05660	COG0791	NLP P60 protein
HNV93_RS05665	COG4948	Mandelate Racemase Muconate Lactonizing
HNV93_RS05670	COG1619	proteins homologs of microcin C7 resistance protein MccF
HNV93_RS05675	COG4166	transmembrane transport
HNV93_RS05680	COG0444	Belongs to the ABC transporter superfamily
HNV93_RS05685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNV93_RS05690	COG0601	transmembrane transport
HNV93_RS05695	COG2362	D-Aminopeptidase
HNV93_RS05700	COG0477	Major facilitator Superfamily
HNV93_RS05705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNV93_RS05715	COG0463	Glycosyl transferase, family 2
HNV93_RS05720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HNV93_RS05725	COG0346	lactoylglutathione lyase activity
HNV93_RS05730	COG0531	amino acid
HNV93_RS05735	COG1392	Phosphate transport regulator
HNV93_RS05740	COG0306	phosphate transporter
HNV93_RS05755	COG5632	N-Acetylmuramoyl-L-alanine amidase
HNV93_RS05755	COG3409	Peptidoglycan-binding domain 1 protein
HNV93_RS05795	COG3778	Protein conserved in bacteria
HNV93_RS05800	COG3299	homolog of phage Mu protein gp47
HNV93_RS05805	COG3628	GPW Gp25 family protein
HNV93_RS05815	COG4193	domain, Protein
HNV93_RS05820	COG1652	LysM domain
HNV93_RS05825	COG5412	phage tail tape measure protein
HNV93_RS05825	COG3953	SLT domain
HNV93_RS05825	COG5412	phage tail tape measure protein
HNV93_RS05825	COG5412	phage tail tape measure protein
HNV93_RS05825	COG3953	SLT domain
HNV93_RS05825	COG3953	SLT domain
HNV93_RS05875	COG4653	Phage capsid family
HNV93_RS05880	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HNV93_RS05885	COG5518	Phage portal protein
HNV93_RS05890	COG1783	phage Terminase large subunit
HNV93_RS05895	COG3728	DNA packaging
HNV93_RS05895	COG5484	DNA packaging
HNV93_RS05900	COG1595	DNA-templated transcription, initiation
HNV93_RS05920	COG1484	DNA-dependent DNA replication
HNV93_RS05925	COG1522	sequence-specific DNA binding
HNV93_RS05930	COG1396	sequence-specific DNA binding
HNV93_RS05935	COG2856	Zn peptidase
HNV93_RS05940	COG4195	phage-related replication protein
HNV93_RS05950	COG3409	Peptidoglycan-binding domain 1 protein
HNV93_RS05950	COG1388	LysM domain
HNV93_RS05950	COG5632	N-Acetylmuramoyl-L-alanine amidase
HNV93_RS05960	COG0457	Tetratricopeptide repeat
HNV93_RS05965	COG2318	DinB family
HNV93_RS05970	COG0730	response to heat
HNV93_RS06005	COG2197	response regulator
HNV93_RS06010	COG4585	Histidine kinase
HNV93_RS06030	COG2770	Histidine kinase
HNV93_RS06030	COG2205	protein histidine kinase activity
HNV93_RS06035	COG0745	RESPONSE REGULATOR receiver
HNV93_RS06040	COG2721	sulfolactate sulfo-lyase activity
HNV93_RS06045	COG0246	Mannitol dehydrogenase
HNV93_RS06050	COG1609	Transcriptional regulator
HNV93_RS06055	COG2211	Major facilitator Superfamily
HNV93_RS06065	COG1252	NADH dehydrogenase
HNV93_RS06075	COG4297	protein containing double-stranded beta helix domain
HNV93_RS06080	COG0697	spore germination
HNV93_RS06085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HNV93_RS06090	COG0390	transport system, permease component
HNV93_RS06095	COG1587	Uroporphyrinogen-III synthase
HNV93_RS06105	COG1819	glycosyl
HNV93_RS06110	COG2124	cytochrome p450
HNV93_RS06115	COG2427	Protein of unknown function (DUF1641)
HNV93_RS06120	COG3383	formate dehydrogenase (NAD+) activity
HNV93_RS06130	COG2205	protein histidine kinase activity
HNV93_RS06145	COG1285	pathogenesis
HNV93_RS06165	COG1349	DNA-binding transcription factor activity
HNV93_RS06175	COG1447	Phosphotransferase system cellobiose-specific component IIA
HNV93_RS06180	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNV93_RS06180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNV93_RS06185	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HNV93_RS06190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HNV93_RS06195	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HNV93_RS06205	COG1846	Transcriptional regulator
HNV93_RS06210	COG0477	Major facilitator Superfamily
HNV93_RS06215	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HNV93_RS06220	COG2367	Beta-lactamase
HNV93_RS06225	COG0346	lactoylglutathione lyase activity
HNV93_RS06235	COG5444	nuclease activity
HNV93_RS06265	COG0626	cystathionine gamma-synthase activity
HNV93_RS06270	COG0626	cystathionine gamma-synthase activity
HNV93_RS06275	COG2382	esterase
HNV93_RS06285	COG2153	protein acetylation
HNV93_RS06295	COG1131	(ABC) transporter
HNV93_RS06315	COG0210	DNA helicase
HNV93_RS06370	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HNV93_RS06375	COG0351	phosphomethylpyrimidine kinase
HNV93_RS06380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HNV93_RS06390	COG2104	thiamine diphosphate biosynthetic process
HNV93_RS06395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNV93_RS06400	COG0352	thiamine-phosphate diphosphorylase activity
HNV93_RS06405	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HNV93_RS06410	COG0475	glutathione-regulated potassium exporter activity
HNV93_RS06410	COG0569	domain protein
HNV93_RS06420	COG0564	pseudouridine synthase activity
HNV93_RS06425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNV93_RS06430	COG2357	RelA SpoT domain protein
HNV93_RS06440	COG4116	CYTH
HNV93_RS06445	COG0741	lytic transglycosylase activity
HNV93_RS06450	COG2346	COG2346, Truncated hemoglobins
HNV93_RS06465	COG1164	Oligoendopeptidase f
HNV93_RS06470	COG4469	Competence protein
HNV93_RS06475	COG4862	establishment of competence for transformation
HNV93_RS06480	COG0861	Integral membrane protein TerC family
HNV93_RS06485	COG1393	Belongs to the ArsC family
HNV93_RS06490	COG0456	acetyltransferase
HNV93_RS06500	COG4608	Belongs to the ABC transporter superfamily
HNV93_RS06505	COG0444	Belongs to the ABC transporter superfamily
HNV93_RS06510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNV93_RS06515	COG0601	transmembrane transport
HNV93_RS06520	COG4166	transmembrane transport
HNV93_RS06525	COG0180	Tryptophanyl-tRNA synthetase
HNV93_RS06535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNV93_RS06540	COG0601	transmembrane transport
HNV93_RS06550	COG4608	Belongs to the ABC transporter superfamily
HNV93_RS06555	COG0444	Belongs to the ABC transporter superfamily
HNV93_RS06560	COG5504	Zn-dependent protease
HNV93_RS06565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HNV93_RS06570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HNV93_RS06585	COG1744	ABC transporter substrate-binding protein PnrA-like
HNV93_RS06595	COG2267	carboxylic ester hydrolase activity
HNV93_RS06610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HNV93_RS06615	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HNV93_RS06620	COG0505	Belongs to the CarA family
HNV93_RS06625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HNV93_RS06635	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HNV93_RS06645	COG2271	Major facilitator Superfamily
HNV93_RS06650	COG0277	FAD linked oxidase domain protein
HNV93_RS06660	COG2151	metal-sulfur cluster biosynthetic enzyme
HNV93_RS06665	COG1073	alpha beta
HNV93_RS06670	COG0561	phosphatase activity
HNV93_RS06690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNV93_RS06695	COG1307	EDD domain protein, DegV family
HNV93_RS06705	COG2124	cytochrome p450
HNV93_RS06710	COG0840	transmembrane signaling receptor activity
HNV93_RS06720	COG2996	Protein conserved in bacteria
HNV93_RS06730	COG0646	methionine synthase
HNV93_RS06730	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HNV93_RS06735	COG2153	protein acetylation
HNV93_RS06740	COG1357	PFAM Pentapeptide repeats (8 copies)
HNV93_RS06745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNV93_RS06750	COG1279	arginine transmembrane transporter activity
HNV93_RS06755	COG2318	DinB family
HNV93_RS06765	COG1917	Cupin 2, conserved barrel domain protein
HNV93_RS06765	COG2207	Transcriptional regulator
HNV93_RS06770	COG0534	Mate efflux family protein
HNV93_RS06775	COG1562	ergosterol biosynthetic process
HNV93_RS06780	COG0367	asparagine synthase
HNV93_RS06795	COG0179	Fumarylacetoacetate (FAA) hydrolase
HNV93_RS06835	COG1403	HNH endonuclease
HNV93_RS06840	COG0419	ATPase involved in DNA repair
HNV93_RS06845	COG0420	3'-5' exonuclease activity
HNV93_RS06860	COG2323	membrane
HNV93_RS06865	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HNV93_RS06875	COG2814	Major facilitator Superfamily
HNV93_RS06880	COG3180	Ammonia monooxygenase
HNV93_RS06885	COG1846	Transcriptional regulator
HNV93_RS06890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HNV93_RS06895	COG0681	Belongs to the peptidase S26 family
HNV93_RS06900	COG0398	Pfam SNARE associated Golgi protein
HNV93_RS06915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNV93_RS06935	COG5646	InterPro IPR014922
HNV93_RS06945	COG4903	ComK protein
HNV93_RS06955	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS06960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNV93_RS06960	COG0723	plastoquinol--plastocyanin reductase activity
HNV93_RS06965	COG0840	transmembrane signaling receptor activity
HNV93_RS06970	COG1268	BioY protein
HNV93_RS06975	COG0318	PFAM AMP-dependent synthetase and ligase
HNV93_RS06980	COG0183	Belongs to the thiolase family
HNV93_RS06985	COG0406	alpha-ribazole phosphatase activity
HNV93_RS06990	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HNV93_RS06995	COG1404	Belongs to the peptidase S8 family
HNV93_RS07000	COG0501	Belongs to the peptidase M48B family
HNV93_RS07010	COG0318	PFAM AMP-dependent synthetase and ligase
HNV93_RS07015	COG0702	epimerase
HNV93_RS07020	COG0095	Lipoate-protein ligase
HNV93_RS07025	COG1234	tRNA 3'-trailer cleavage
HNV93_RS07035	COG1301	dicarboxylic acid transport
HNV93_RS07040	COG1363	Peptidase, m42
HNV93_RS07050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HNV93_RS07055	COG1511	domain protein
HNV93_RS07060	COG1309	transcriptional regulator
HNV93_RS07080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HNV93_RS07085	COG2329	Antibiotic biosynthesis monooxygenase
HNV93_RS07090	COG3069	C4-dicarboxylate transmembrane transporter activity
HNV93_RS07095	COG1473	amidohydrolase
HNV93_RS07105	COG4473	ABC transporter
HNV93_RS07110	COG1131	(ABC) transporter
HNV93_RS07115	COG0537	adenosine 5'-monophosphoramidase activity
HNV93_RS07120	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HNV93_RS07135	COG4980	gas vesicle protein
HNV93_RS07170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HNV93_RS07185	COG4717	serine-type aminopeptidase activity
HNV93_RS07190	COG0420	3'-5' exonuclease activity
HNV93_RS07195	COG1668	transmembrane transport
HNV93_RS07200	COG4152	abc transporter atp-binding protein
HNV93_RS07210	COG1024	Enoyl-CoA hydratase
HNV93_RS07220	COG0490	domain, Protein
HNV93_RS07225	COG0475	glutathione-regulated potassium exporter activity
HNV93_RS07235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HNV93_RS07240	COG0561	phosphatase activity
HNV93_RS07245	COG4335	DNA alkylation repair
HNV93_RS07260	COG0189	ligase activity
HNV93_RS07265	COG0189	ligase activity
HNV93_RS07280	COG0702	epimerase
HNV93_RS07285	COG1132	(ABC) transporter
HNV93_RS07290	COG1132	(ABC) transporter
HNV93_RS07295	COG0589	response to stress
HNV93_RS07305	COG3226	Transcriptional regulator
HNV93_RS07310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HNV93_RS07315	COG0726	polysaccharide deacetylase
HNV93_RS07320	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HNV93_RS07325	COG0668	transmembrane transport
HNV93_RS07335	COG0584	glycerophosphoryl diester phosphodiesterase
HNV93_RS07340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNV93_RS07345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNV93_RS07350	COG1253	flavin adenine dinucleotide binding
HNV93_RS07355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HNV93_RS07360	COG0436	Aminotransferase
HNV93_RS07365	COG0789	Transcriptional regulator
HNV93_RS07370	COG1253	flavin adenine dinucleotide binding
HNV93_RS07375	COG0204	Acyl-transferase
HNV93_RS07380	COG1595	DNA-templated transcription, initiation
HNV93_RS07395	COG0733	neurotransmitter:sodium symporter activity
HNV93_RS07400	COG0531	amino acid
HNV93_RS07405	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS07410	COG0372	Belongs to the citrate synthase family
HNV93_RS07415	COG0583	DNA-binding transcription factor activity
HNV93_RS07420	COG1388	LysM domain
HNV93_RS07420	COG0791	NLP P60 protein
HNV93_RS07425	COG1785	Belongs to the alkaline phosphatase family
HNV93_RS07430	COG2719	SpoVR family
HNV93_RS07435	COG0668	transmembrane transport
HNV93_RS07440	COG1959	2 iron, 2 sulfur cluster binding
HNV93_RS07445	COG1388	LysM domain
HNV93_RS07445	COG0791	NLP P60 protein
HNV93_RS07460	COG0431	NADPH-dependent FMN reductase
HNV93_RS07465	COG2197	response regulator
HNV93_RS07470	COG2203	Gaf domain
HNV93_RS07470	COG4585	Histidine kinase
HNV93_RS07475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HNV93_RS07480	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HNV93_RS07490	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HNV93_RS07495	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HNV93_RS07500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HNV93_RS07505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HNV93_RS07505	COG3153	acetyltransferase
HNV93_RS07510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HNV93_RS07515	COG0517	IMP dehydrogenase activity
HNV93_RS07525	COG0564	pseudouridine synthase activity
HNV93_RS07530	COG3764	Sortase (surface protein transpeptidase)
HNV93_RS07535	COG1525	nuclease
HNV93_RS07535	COG4085	toxin activity
HNV93_RS07535	COG0737	Belongs to the 5'-nucleotidase family
HNV93_RS07540	COG5577	PFAM Coat F domain
HNV93_RS07560	COG1823	symporter activity
HNV93_RS07565	COG3706	GGDEF domain
HNV93_RS07570	COG1464	Belongs to the NlpA lipoprotein family
HNV93_RS07575	COG1278	Cold shock
HNV93_RS07580	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HNV93_RS07595	COG0655	NAD(P)H dehydrogenase (quinone) activity
HNV93_RS07600	COG2814	Major facilitator Superfamily
HNV93_RS07605	COG1566	PFAM secretion protein HlyD family protein
HNV93_RS07610	COG1846	Transcriptional regulator
HNV93_RS07620	COG2766	serine protein kinase
HNV93_RS07625	COG1664	Polymer-forming cytoskeletal
HNV93_RS07630	COG1664	Polymer-forming cytoskeletal
HNV93_RS07635	COG0789	Transcriptional regulator
HNV93_RS07640	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HNV93_RS07650	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HNV93_RS07655	COG3382	B3 4 domain protein
HNV93_RS07665	COG1476	TRANSCRIPTIONal
HNV93_RS07685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HNV93_RS07690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HNV93_RS07695	COG1116	anion transmembrane transporter activity
HNV93_RS07705	COG0753	catalase activity
HNV93_RS07710	COG4608	Belongs to the ABC transporter superfamily
HNV93_RS07715	COG0444	Belongs to the ABC transporter superfamily
HNV93_RS07720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNV93_RS07725	COG0601	transmembrane transport
HNV93_RS07730	COG0747	negative chemotaxis
HNV93_RS07740	COG0277	FAD linked oxidase domain protein
HNV93_RS07750	COG3340	Belongs to the peptidase S51 family
HNV93_RS07865	COG0735	belongs to the Fur family
HNV93_RS07870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HNV93_RS07880	COG4129	membrane
HNV93_RS07885	COG1132	(ABC) transporter
HNV93_RS07905	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS07915	COG1194	a g-specific adenine glycosylase
HNV93_RS07920	COG1988	membrane-bound metal-dependent
HNV93_RS07925	COG4485	Bacterial membrane protein, YfhO
HNV93_RS07930	COG0463	Glycosyl transferase, family 2
HNV93_RS07935	COG0596	Alpha beta hydrolase
HNV93_RS07940	COG5658	integral membrane protein
HNV93_RS07945	COG3103	Sh3 type 3 domain protein
HNV93_RS07960	COG3591	Belongs to the peptidase S1B family
HNV93_RS07970	COG2814	Major facilitator Superfamily
HNV93_RS07985	COG1090	epimerase
HNV93_RS08000	COG0778	Nitroreductase
HNV93_RS08005	COG0384	phenazine biosynthesis protein PhzF
HNV93_RS08010	COG0392	lysyltransferase activity
HNV93_RS08010	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HNV93_RS08015	COG1846	Transcriptional regulator
HNV93_RS08020	COG2814	Major facilitator Superfamily
HNV93_RS08025	COG2318	DinB family
HNV93_RS08030	COG2732	(Barnase) inhibitor
HNV93_RS08035	COG0574	Belongs to the PEP-utilizing enzyme family
HNV93_RS08035	COG3848	Pyruvate phosphate dikinase
HNV93_RS08040	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HNV93_RS08045	COG2249	NAD(P)H dehydrogenase (quinone) activity
HNV93_RS08050	COG1695	Transcriptional regulator
HNV93_RS08060	COG2514	catechol 2,3-dioxygenase activity
HNV93_RS08065	COG2259	Doxx family
HNV93_RS08070	COG1132	(ABC) transporter
HNV93_RS08075	COG1132	(ABC) transporter
HNV93_RS08085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HNV93_RS08085	COG1263	PTS System
HNV93_RS08090	COG1737	Transcriptional regulator
HNV93_RS08095	COG1486	melibiose metabolic process
HNV93_RS08105	COG3284	Transcriptional regulator
HNV93_RS08110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HNV93_RS08115	COG0508	dehydrogenase complex catalyzes the overall conversion of
HNV93_RS08120	COG0022	dehydrogenase e1 component
HNV93_RS08125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HNV93_RS08130	COG4637	Psort location Cytoplasmic, score
HNV93_RS08135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HNV93_RS08145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNV93_RS08150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HNV93_RS08155	COG0598	Magnesium transport protein CorA
HNV93_RS08165	COG2084	Dehydrogenase
HNV93_RS08170	COG2205	protein histidine kinase activity
HNV93_RS08175	COG0745	RESPONSE REGULATOR receiver
HNV93_RS08195	COG0726	polysaccharide deacetylase
HNV93_RS08205	COG0535	radical SAM domain protein
HNV93_RS08210	COG0668	transmembrane transport
HNV93_RS08220	COG0387	Pfam Sodium calcium exchanger
HNV93_RS08225	COG0477	Major facilitator Superfamily
HNV93_RS08230	COG1295	ribonuclease BN
HNV93_RS08235	COG4980	gas vesicle protein
HNV93_RS08240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNV93_RS08250	COG2814	Major facilitator Superfamily
HNV93_RS08265	COG1609	Transcriptional regulator
HNV93_RS08270	COG0693	protein deglycase activity
HNV93_RS08275	COG0737	Belongs to the 5'-nucleotidase family
HNV93_RS08290	COG0778	Nitroreductase
HNV93_RS08295	COG2188	Transcriptional regulator
HNV93_RS08300	COG0366	Alpha amylase catalytic
HNV93_RS08305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HNV93_RS08305	COG1263	PTS System
HNV93_RS08320	COG0071	Belongs to the small heat shock protein (HSP20) family
HNV93_RS08330	COG1368	sulfuric ester hydrolase activity
HNV93_RS08340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HNV93_RS08340	COG1263	PTS System
HNV93_RS08345	COG0024	Methionine aminopeptidase
HNV93_RS08365	COG2258	MOSC domain
HNV93_RS08375	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HNV93_RS08380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNV93_RS08385	COG2851	Citrate transporter
HNV93_RS08390	COG3181	Tripartite tricarboxylate transporter family receptor
HNV93_RS08395	COG4565	transcriptional regulatory protein
HNV93_RS08400	COG3290	protein histidine kinase activity
HNV93_RS08420	COG0471	metal ion transport
HNV93_RS08425	COG3866	Pectate lyase
HNV93_RS08440	COG2130	NADP-dependent
HNV93_RS08445	COG0456	acetyltransferase
HNV93_RS08450	COG0513	Belongs to the DEAD box helicase family
HNV93_RS08455	COG0488	(ABC) transporter
HNV93_RS08460	COG2814	Major facilitator Superfamily
HNV93_RS08465	COG0789	Transcriptional regulator
HNV93_RS08470	COG0488	(ABC) transporter
HNV93_RS08475	COG0463	Glycosyl transferase, family 2
HNV93_RS08475	COG0457	Tetratricopeptide repeat
HNV93_RS08480	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS08485	COG0840	transmembrane signaling receptor activity
HNV93_RS08490	COG1012	belongs to the aldehyde dehydrogenase family
HNV93_RS08495	COG0531	amino acid
HNV93_RS08500	COG2223	nitrite transmembrane transporter activity
HNV93_RS08505	COG1442	glycosyl transferase family 8
HNV93_RS08510	COG1216	Glycosyl transferase, family 2
HNV93_RS08515	COG1442	glycosyl transferase family 8
HNV93_RS08520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNV93_RS08525	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HNV93_RS08530	COG1368	sulfuric ester hydrolase activity
HNV93_RS08535	COG2124	cytochrome p450
HNV93_RS08535	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HNV93_RS08545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HNV93_RS08550	COG1846	Transcriptional regulator
HNV93_RS08555	COG0670	Belongs to the BI1 family
HNV93_RS08560	COG0196	riboflavin kinase activity
HNV93_RS08565	COG5583	Uncharacterized small protein (DUF2292)
HNV93_RS08570	COG1366	Belongs to the anti-sigma-factor antagonist family
HNV93_RS08575	COG0346	lactoylglutathione lyase activity
HNV93_RS08580	COG2329	Antibiotic biosynthesis monooxygenase
HNV93_RS08585	COG2323	membrane
HNV93_RS08595	COG0454	-acetyltransferase
HNV93_RS08600	COG3546	catalase activity
HNV93_RS08630	COG5444	nuclease activity
HNV93_RS08670	COG1131	(ABC) transporter
HNV93_RS08680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNV93_RS08685	COG1597	lipid kinase activity
HNV93_RS08690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HNV93_RS08695	COG1309	transcriptional regulator
HNV93_RS08715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNV93_RS08720	COG1285	pathogenesis
HNV93_RS08725	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HNV93_RS08730	COG4851	CamS sex pheromone cAM373 precursor
HNV93_RS08740	COG0210	DNA helicase
HNV93_RS08750	COG0069	glutamate synthase activity
HNV93_RS08755	COG4496	protein, YerC YecD
HNV93_RS08760	COG1470	cell adhesion involved in biofilm formation
HNV93_RS08765	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HNV93_RS08775	COG0151	Belongs to the GarS family
HNV93_RS08780	COG0138	bifunctional purine biosynthesis protein purh
HNV93_RS08785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HNV93_RS08795	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HNV93_RS08810	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HNV93_RS08815	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HNV93_RS08820	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HNV93_RS08825	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HNV93_RS08830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HNV93_RS08850	COG3064	Membrane
HNV93_RS08855	COG2252	PERMEase
HNV93_RS08880	COG1305	Transglutaminase-like
HNV93_RS08885	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
HNV93_RS08890	COG0714	Associated with various cellular activities
HNV93_RS08895	COG1113	amino acid transport
HNV93_RS08900	COG2132	Multicopper oxidase
HNV93_RS08910	COG0823	Involved in the tonB-independent uptake of proteins
HNV93_RS08915	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HNV93_RS08920	COG1063	alcohol dehydrogenase
HNV93_RS08925	COG1595	DNA-templated transcription, initiation
HNV93_RS08935	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HNV93_RS08935	COG2755	lipolytic protein G-D-S-L family
HNV93_RS08940	COG4260	virion core protein, lumpy skin disease virus
HNV93_RS08945	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HNV93_RS08950	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HNV93_RS08955	COG1842	Phage shock protein A
HNV93_RS08965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HNV93_RS08970	COG2211	Major facilitator Superfamily
HNV93_RS08975	COG1063	alcohol dehydrogenase
HNV93_RS08980	COG0457	Tetratricopeptide repeat
HNV93_RS09020	COG1266	CAAX protease self-immunity
HNV93_RS09030	COG0805	protein transport
HNV93_RS09035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HNV93_RS09050	COG0488	(ABC) transporter
HNV93_RS09055	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HNV93_RS09060	COG0456	acetyltransferase
HNV93_RS09065	COG1214	PFAM Peptidase M22, glycoprotease
HNV93_RS09070	COG0802	atpase or kinase
HNV93_RS09075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HNV93_RS09115	COG2814	Major facilitator Superfamily
HNV93_RS09120	COG0604	alcohol dehydrogenase
HNV93_RS09125	COG3832	glyoxalase III activity
HNV93_RS09135	COG0531	amino acid
HNV93_RS09140	COG1309	transcriptional regulator
HNV93_RS09145	COG2076	Multidrug Resistance protein
HNV93_RS09150	COG2076	Multidrug Resistance protein
HNV93_RS09155	COG2807	transmembrane transport
HNV93_RS09160	COG2186	Transcriptional regulator
HNV93_RS09165	COG2188	Transcriptional regulator
HNV93_RS09170	COG2814	Major facilitator Superfamily
HNV93_RS09175	COG1388	LysM domain
HNV93_RS09185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HNV93_RS09200	COG1819	glycosyl
HNV93_RS09205	COG1802	Transcriptional regulator
HNV93_RS09210	COG0473	3-isopropylmalate dehydrogenase activity
HNV93_RS09215	COG2226	methyltransferase
HNV93_RS09220	COG1051	belongs to the nudix hydrolase family
HNV93_RS09225	COG0697	spore germination
HNV93_RS09230	COG0789	Transcriptional regulator
HNV93_RS09230	COG4978	Transcriptional regulator
HNV93_RS09235	COG0456	acetyltransferase
HNV93_RS09240	COG0730	response to heat
HNV93_RS09250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HNV93_RS09255	COG2814	Major facilitator Superfamily
HNV93_RS09265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNV93_RS09270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HNV93_RS09280	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HNV93_RS09285	COG2409	Drug exporters of the RND superfamily
HNV93_RS09290	COG2197	response regulator
HNV93_RS09295	COG4585	Histidine kinase
HNV93_RS09305	COG5577	PFAM Coat F domain
HNV93_RS09310	COG1063	alcohol dehydrogenase
HNV93_RS09320	COG5577	PFAM Coat F domain
HNV93_RS09325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNV93_RS09330	COG0697	spore germination
HNV93_RS09335	COG1309	transcriptional regulator
HNV93_RS09340	COG2814	Major facilitator Superfamily
HNV93_RS09350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNV93_RS09360	COG0789	Transcriptional regulator
HNV93_RS09365	COG1064	alcohol dehydrogenase
HNV93_RS09400	COG2318	DinB family
HNV93_RS09405	COG0662	Cupin 2, conserved barrel domain protein
HNV93_RS09425	COG0277	FAD linked oxidase domain protein
HNV93_RS09440	COG0662	Cupin 2, conserved barrel domain protein
HNV93_RS09450	COG3621	Patatin-like phospholipase
HNV93_RS09465	COG1794	racemase activity, acting on amino acids and derivatives
HNV93_RS09470	COG0730	response to heat
HNV93_RS09475	COG0425	Belongs to the sulfur carrier protein TusA family
HNV93_RS09480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNV93_RS09480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNV93_RS09485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNV93_RS09485	COG0425	Belongs to the sulfur carrier protein TusA family
HNV93_RS09495	COG2210	Belongs to the sulfur carrier protein TusA family
HNV93_RS09500	COG1937	Protein conserved in bacteria
HNV93_RS09505	COG1329	Transcriptional regulator
HNV93_RS09510	COG1278	Cold shock
HNV93_RS09525	COG2910	NAD(P)H-binding
HNV93_RS09530	COG1959	2 iron, 2 sulfur cluster binding
HNV93_RS09545	COG2030	dehydratase
HNV93_RS09555	COG1846	Transcriptional regulator
HNV93_RS09560	COG0477	Major facilitator Superfamily
HNV93_RS09575	COG0457	Tetratricopeptide repeat
HNV93_RS09580	COG5444	nuclease activity
HNV93_RS09645	COG2183	response to ionizing radiation
HNV93_RS09650	COG2208	phosphoserine phosphatase activity
HNV93_RS09655	COG1191	sigma factor activity
HNV93_RS09665	COG1366	Belongs to the anti-sigma-factor antagonist family
HNV93_RS09670	COG2208	phosphoserine phosphatase activity
HNV93_RS09675	COG2172	sigma factor antagonist activity
HNV93_RS09680	COG1366	Belongs to the anti-sigma-factor antagonist family
HNV93_RS09685	COG1366	Belongs to the anti-sigma-factor antagonist family
HNV93_RS09690	COG2337	Toxic component of a toxin-antitoxin (TA) module
HNV93_RS09695	COG0864	Transcriptional regulator
HNV93_RS09700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HNV93_RS09705	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HNV93_RS09715	COG0705	Rhomboid family
HNV93_RS09720	COG3428	Bacterial PH domain
HNV93_RS09725	COG3402	PFAM membrane-flanked domain
HNV93_RS09730	COG0513	Belongs to the DEAD box helicase family
HNV93_RS09735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HNV93_RS09745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNV93_RS09750	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HNV93_RS09765	COG1960	acyl-CoA dehydrogenase activity
HNV93_RS09775	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HNV93_RS09780	COG1131	(ABC) transporter
HNV93_RS09785	COG0628	permease
HNV93_RS09790	COG1301	dicarboxylic acid transport
HNV93_RS09795	COG4565	transcriptional regulatory protein
HNV93_RS09800	COG3290	protein histidine kinase activity
HNV93_RS09805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HNV93_RS09810	COG3546	catalase activity
HNV93_RS09815	COG2329	Antibiotic biosynthesis monooxygenase
HNV93_RS09820	COG0662	Cupin 2, conserved barrel domain protein
HNV93_RS09825	COG3729	General stress protein
HNV93_RS09830	COG2217	Heavy metal translocating P-type atpase
HNV93_RS09835	COG2076	Multidrug Resistance protein
HNV93_RS09845	COG4876	unkown
HNV93_RS09855	COG1914	H( )-stimulated, divalent metal cation uptake system
HNV93_RS09875	COG0457	Tetratricopeptide repeat
HNV93_RS09900	COG0028	Belongs to the TPP enzyme family
HNV93_RS09910	COG0531	amino acid
HNV93_RS09920	COG1215	transferase activity, transferring glycosyl groups
HNV93_RS09925	COG5298	Protein conserved in bacteria
HNV93_RS09930	COG3706	GGDEF domain
HNV93_RS09935	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HNV93_RS09940	COG0551	DNA topoisomerase type I activity
HNV93_RS09940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HNV93_RS09945	COG1522	sequence-specific DNA binding
HNV93_RS09950	COG2814	Major facilitator Superfamily
HNV93_RS09960	COG3871	stress protein (general stress protein 26)
HNV93_RS09965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HNV93_RS09970	COG1917	Cupin 2, conserved barrel domain protein
HNV93_RS09975	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS09980	COG0318	PFAM AMP-dependent synthetase and ligase
HNV93_RS09985	COG3711	transcriptional antiterminator
HNV93_RS09990	COG4989	oxidoreductase activity
HNV93_RS09995	COG0768	penicillin binding
HNV93_RS10000	COG2329	Antibiotic biosynthesis monooxygenase
HNV93_RS10010	COG2755	lipolytic protein G-D-S-L family
HNV93_RS10015	COG1414	Transcriptional regulator
HNV93_RS10020	COG1984	allophanate hydrolase subunit 2
HNV93_RS10025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HNV93_RS10035	COG1914	H( )-stimulated, divalent metal cation uptake system
HNV93_RS10045	COG0561	phosphatase activity
HNV93_RS10055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HNV93_RS10065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNV93_RS10070	COG2213	PTS system mannitol-specific
HNV93_RS10080	COG1349	DNA-binding transcription factor activity
HNV93_RS10085	COG2372	response to copper ion
HNV93_RS10085	COG1276	copper resistance
HNV93_RS10090	COG4549	nuclear export factor GLE1
HNV93_RS10095	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS10100	COG4975	Glucose uptake
HNV93_RS10105	COG1012	belongs to the aldehyde dehydrogenase family
HNV93_RS10110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HNV93_RS10115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNV93_RS10120	COG0640	Transcriptional regulator
HNV93_RS10125	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HNV93_RS10130	COG0778	Nitroreductase
HNV93_RS10135	COG1309	transcriptional regulator
HNV93_RS10140	COG2814	Major facilitator Superfamily
HNV93_RS10145	COG4607	ABC-type enterochelin transport system periplasmic component
HNV93_RS10150	COG4604	ABC transporter, ATP-binding protein
HNV93_RS10155	COG4605	iron ion homeostasis
HNV93_RS10160	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNV93_RS10165	COG0527	aspartate kinase activity
HNV93_RS10180	COG0457	Tetratricopeptide repeat
HNV93_RS10185	COG5002	protein histidine kinase activity
HNV93_RS10185	COG3850	Histidine kinase
HNV93_RS10190	COG0745	RESPONSE REGULATOR receiver
HNV93_RS10195	COG0577	efflux transmembrane transporter activity
HNV93_RS10200	COG1136	(ABC) transporter
HNV93_RS10205	COG2079	MmgE PrpD family protein
HNV93_RS10210	COG1473	amidohydrolase
HNV93_RS10215	COG1126	abc transporter atp-binding protein
HNV93_RS10220	COG0765	amino acid transport
HNV93_RS10225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNV93_RS10230	COG0456	acetyltransferase
HNV93_RS10235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNV93_RS10240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HNV93_RS10250	COG0697	spore germination
HNV93_RS10260	COG5434	Belongs to the glycosyl hydrolase 28 family
HNV93_RS10265	COG3104	oligopeptide transport
HNV93_RS10280	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HNV93_RS10285	COG0163	prenyltransferase activity
HNV93_RS10290	COG0583	DNA-binding transcription factor activity
HNV93_RS10300	COG0765	amino acid transport
HNV93_RS10305	COG1126	abc transporter atp-binding protein
HNV93_RS10310	COG2364	Membrane
HNV93_RS10325	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HNV93_RS10330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS10335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS10340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS10345	COG1733	regulation of RNA biosynthetic process
HNV93_RS10350	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HNV93_RS10355	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HNV93_RS10360	COG3209	COG3209 Rhs family protein
HNV93_RS10375	COG2723	6-phospho-beta-galactosidase activity
HNV93_RS10385	COG1714	RDD family
HNV93_RS10390	COG1063	alcohol dehydrogenase
HNV93_RS10395	COG0523	cobalamin synthesis protein
HNV93_RS10400	COG2223	nitrite transmembrane transporter activity
HNV93_RS10405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HNV93_RS10410	COG0243	molybdopterin cofactor binding
HNV93_RS10415	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HNV93_RS10420	COG2146	nitrite reductase [NAD(P)H] activity
HNV93_RS10425	COG1587	Uroporphyrinogen-III synthase
HNV93_RS10425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HNV93_RS10435	COG2508	Transcriptional regulator
HNV93_RS10440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNV93_RS10445	COG1012	belongs to the aldehyde dehydrogenase family
HNV93_RS10450	COG0506	proline dehydrogenase activity
HNV93_RS10455	COG3541	Predicted nucleotidyltransferase
HNV93_RS10460	COG3458	cephalosporin-C deacetylase activity
HNV93_RS10465	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HNV93_RS10470	COG2271	Major facilitator Superfamily
HNV93_RS10475	COG1082	Xylose isomerase domain protein TIM barrel
HNV93_RS10480	COG1660	Displays ATPase and GTPase activities
HNV93_RS10495	COG3665	Urea carboxylase-associated protein
HNV93_RS10500	COG1113	amino acid transport
HNV93_RS10505	COG3403	YqcI/YcgG family
HNV93_RS10510	COG1280	lysine exporter protein (LysE YggA)
HNV93_RS10515	COG1846	Transcriptional regulator
HNV93_RS10520	COG2814	Major facilitator Superfamily
HNV93_RS10540	COG1288	antiporter activity
HNV93_RS10545	COG1473	amidohydrolase
HNV93_RS10550	COG2113	Glycine betaine
HNV93_RS10555	COG4176	ABC-type proline glycine betaine transport system permease component
HNV93_RS10560	COG0517	IMP dehydrogenase activity
HNV93_RS10560	COG4175	Glycine betaine
HNV93_RS10565	COG0477	Major facilitator Superfamily
HNV93_RS10570	COG3853	Toxic anion resistance protein (TelA)
HNV93_RS10580	COG0861	Integral membrane protein TerC family
HNV93_RS10585	COG2310	stress, protein
HNV93_RS10590	COG2310	stress, protein
HNV93_RS10595	COG2310	stress, protein
HNV93_RS10600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNV93_RS10605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HNV93_RS10610	COG1121	(ABC) transporter
HNV93_RS10615	COG0803	Belongs to the bacterial solute-binding protein 9 family
HNV93_RS10620	COG0366	Alpha amylase catalytic
HNV93_RS10625	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS10630	COG0457	Tetratricopeptide repeat
HNV93_RS10635	COG1876	peptidase activity
HNV93_RS10640	COG1595	DNA-templated transcription, initiation
HNV93_RS10645	COG1595	DNA-templated transcription, initiation
HNV93_RS10660	COG1405	negative regulation of cell septum assembly
HNV93_RS10660	COG3012	SEC-C Motif Domain Protein
HNV93_RS10665	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HNV93_RS10670	COG0252	asparaginase activity
HNV93_RS10675	COG1309	transcriptional regulator
HNV93_RS10680	COG0477	Major facilitator Superfamily
HNV93_RS10685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HNV93_RS10695	COG0805	protein transport
HNV93_RS10700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HNV93_RS10705	COG3540	Alkaline phosphatase
HNV93_RS10710	COG3773	Cell wall hydrolase
HNV93_RS10725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNV93_RS10730	COG2259	Doxx family
HNV93_RS10735	COG0346	lactoylglutathione lyase activity
HNV93_RS10740	COG0778	Nitroreductase
HNV93_RS10745	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HNV93_RS10765	COG0784	Response regulator, receiver
HNV93_RS10770	COG4191	Histidine kinase
HNV93_RS10775	COG2066	Belongs to the glutaminase family
HNV93_RS10780	COG1115	amino acid carrier protein
HNV93_RS10785	COG2040	homocysteine
HNV93_RS10790	COG0833	amino acid
HNV93_RS10795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HNV93_RS10800	COG1301	dicarboxylic acid transport
HNV93_RS10815	COG0688	phosphatidylethanolamine metabolic process
HNV93_RS10820	COG0586	Pfam SNARE associated Golgi protein
HNV93_RS10825	COG1183	phosphatidylcholine synthase activity
HNV93_RS10835	COG0371	Dehydrogenase
HNV93_RS10845	COG5444	nuclease activity
HNV93_RS10850	COG1397	ADP-ribosylglycohydrolase
HNV93_RS10865	COG3409	Peptidoglycan-binding domain 1 protein
HNV93_RS10875	COG2368	4-hydroxyphenylacetate
HNV93_RS10885	COG2271	Major facilitator Superfamily
HNV93_RS10890	COG0584	glycerophosphoryl diester phosphodiesterase
HNV93_RS10905	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HNV93_RS10910	COG0531	amino acid
HNV93_RS10950	COG1131	(ABC) transporter
HNV93_RS10955	COG2197	response regulator
HNV93_RS10960	COG4585	Histidine kinase
HNV93_RS10965	COG1011	Hydrolase
HNV93_RS10970	COG1113	amino acid transport
HNV93_RS10975	COG1846	Transcriptional regulator
HNV93_RS10980	COG1380	Effector of murein hydrolase LrgA
HNV93_RS10985	COG1346	cytolysis
HNV93_RS11005	COG0577	efflux transmembrane transporter activity
HNV93_RS11010	COG1136	(ABC) transporter
HNV93_RS11015	COG5002	protein histidine kinase activity
HNV93_RS11045	COG4856	YbbR-like protein
HNV93_RS11050	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HNV93_RS11055	COG5662	AntiSigma factor
HNV93_RS11060	COG1595	DNA-templated transcription, initiation
HNV93_RS11090	COG1683	Conserved Protein
HNV93_RS11095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HNV93_RS11105	COG1263	PTS System
HNV93_RS11105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HNV93_RS11110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HNV93_RS11115	COG1472	Belongs to the glycosyl hydrolase 3 family
HNV93_RS11120	COG3876	Protein conserved in bacteria
HNV93_RS11125	COG2207	Transcriptional regulator
HNV93_RS11125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HNV93_RS11130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HNV93_RS11135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNV93_RS11140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNV93_RS11145	COG2819	hydrolase of the alpha beta superfamily
HNV93_RS11150	COG0385	Bile acid
HNV93_RS11155	COG0659	secondary active sulfate transmembrane transporter activity
HNV93_RS11160	COG1063	alcohol dehydrogenase
HNV93_RS11170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HNV93_RS11175	COG0738	Major facilitator superfamily
HNV93_RS11235	COG0726	polysaccharide deacetylase
HNV93_RS11240	COG2194	sulfuric ester hydrolase activity
HNV93_RS11250	COG0489	protein tyrosine kinase activity
HNV93_RS11255	COG0860	N-Acetylmuramoyl-L-alanine amidase
HNV93_RS11265	COG2318	DinB family
HNV93_RS11270	COG2226	methyltransferase
HNV93_RS11290	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNV93_RS11295	COG1122	ATPase activity
HNV93_RS11300	COG1122	ATPase activity
HNV93_RS11325	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HNV93_RS11335	COG0024	Methionine aminopeptidase
HNV93_RS11345	COG0201	protein transport
HNV93_RS11360	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HNV93_RS11455	COG0596	Alpha beta hydrolase
HNV93_RS11480	COG1358	cellular component organization or biogenesis
HNV93_RS11495	COG2813	Specifically methylates the guanine in position
HNV93_RS11520	COG0250	Participates in transcription elongation, termination and antitermination
HNV93_RS11525	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HNV93_RS11535	COG1595	DNA-templated transcription, initiation
HNV93_RS11540	COG3688	RNA-binding protein containing a PIN domain
HNV93_RS11545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNV93_RS11550	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HNV93_RS11560	COG1045	serine acetyltransferase
HNV93_RS11580	COG4956	integral membrane protein (PIN domain superfamily)
HNV93_RS11585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HNV93_RS11590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HNV93_RS11595	COG0542	response to heat
HNV93_RS11605	COG3880	PFAM UvrB UvrC protein
HNV93_RS11610	COG4463	regulation of RNA biosynthetic process
HNV93_RS11690	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HNV93_RS11695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HNV93_RS11700	COG1396	sequence-specific DNA binding
HNV93_RS11705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HNV93_RS11710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HNV93_RS11715	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HNV93_RS11720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HNV93_RS11725	COG0512	Glutamine amidotransferase of anthranilate synthase
HNV93_RS11730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HNV93_RS11735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HNV93_RS11740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HNV93_RS11755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HNV93_RS11765	COG0037	tRNA processing
HNV93_RS11770	COG0515	serine threonine protein kinase
HNV93_RS11775	COG2304	oxidoreductase activity
HNV93_RS11780	COG2208	phosphoserine phosphatase activity
HNV93_RS11795	COG1098	S1 RNA binding domain
HNV93_RS11800	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HNV93_RS11815	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HNV93_RS11820	COG3956	TIGRFAM MazG family protein
HNV93_RS11825	COG2244	polysaccharide biosynthetic process
HNV93_RS11830	COG2002	toxin-antitoxin pair type II binding
HNV93_RS11835	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HNV93_RS11855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNV93_RS11870	COG0251	oxidation-reduction process
HNV93_RS11875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HNV93_RS11890	COG4466	Protein conserved in bacteria
HNV93_RS11900	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HNV93_RS11905	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HNV93_RS11915	COG0084	hydrolase, TatD family'
HNV93_RS11920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNV93_RS11920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNV93_RS11925	COG2002	toxin-antitoxin pair type II binding
HNV93_RS11930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HNV93_RS11940	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HNV93_RS11950	COG1774	PSP1 C-terminal conserved region
HNV93_RS11955	COG0470	DNA polymerase III
HNV93_RS11960	COG1728	Protein conserved in bacteria
HNV93_RS11965	COG3870	Protein conserved in bacteria
HNV93_RS11975	COG1982	Orn Lys Arg decarboxylase major
HNV93_RS11980	COG3853	Toxic anion resistance protein (TelA)
HNV93_RS11985	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HNV93_RS12030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HNV93_RS12035	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HNV93_RS12040	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNV93_RS12050	COG0590	tRNA wobble adenosine to inosine editing
HNV93_RS12055	COG1335	isochorismatase
HNV93_RS12060	COG3858	chitin binding
HNV93_RS12060	COG1388	LysM domain
HNV93_RS12065	COG1428	Deoxynucleoside kinase
HNV93_RS12070	COG1428	Deoxynucleoside kinase
HNV93_RS12080	COG1929	Belongs to the glycerate kinase type-1 family
HNV93_RS12100	COG1686	Belongs to the peptidase S11 family
HNV93_RS12105	COG0516	GMP reductase activity
HNV93_RS12105	COG0517	IMP dehydrogenase activity
HNV93_RS12140	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNV93_RS12145	COG0187	DNA topoisomerase II activity
HNV93_RS12160	COG2501	S4 domain
HNV93_RS12165	COG0592	DNA-directed DNA polymerase activity
HNV93_RS12185	COG0706	membrane insertase activity
HNV93_RS12190	COG1847	R3H domain protein
HNV93_RS12215	COG1192	Involved in chromosome partitioning
HNV93_RS12220	COG1475	DNA binding
HNV93_RS12235	COG3949	Membrane
HNV93_RS12240	COG4481	Protein conserved in bacteria
HNV93_RS12245	COG0243	molybdopterin cofactor binding
HNV93_RS12250	COG0012	GTP binding
HNV93_RS12260	COG0629	single-stranded DNA binding
HNV93_RS12270	COG2169	Transcriptional regulator
HNV93_RS12275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HNV93_RS12280	COG0708	Exodeoxyribonuclease III
HNV93_RS12285	COG1609	Transcriptional regulator
HNV93_RS12290	COG0346	lactoylglutathione lyase activity
HNV93_RS12295	COG2814	Major facilitator Superfamily
HNV93_RS12295	COG0477	Major facilitator Superfamily
HNV93_RS12300	COG1266	CAAX protease self-immunity
HNV93_RS12305	COG1331	Highly conserved protein containing a thioredoxin domain
HNV93_RS12330	COG1331	Highly conserved protein containing a thioredoxin domain
HNV93_RS12335	COG0697	spore germination
HNV93_RS12340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNV93_RS12345	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS12350	COG0583	DNA-binding transcription factor activity
HNV93_RS12355	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HNV93_RS12365	COG2153	protein acetylation
HNV93_RS12370	COG1846	Transcriptional regulator
HNV93_RS12375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNV93_RS12380	COG1846	Transcriptional regulator
HNV93_RS12385	COG0778	Nitroreductase
HNV93_RS12395	COG2211	Major facilitator Superfamily
HNV93_RS12400	COG2318	DinB family
HNV93_RS12410	COG1621	beta-fructofuranosidase activity
HNV93_RS12415	COG1621	beta-fructofuranosidase activity
HNV93_RS12420	COG0697	spore germination
HNV93_RS12430	COG1733	regulation of RNA biosynthetic process
HNV93_RS12435	COG5577	PFAM Coat F domain
HNV93_RS12445	COG4241	membrane
HNV93_RS12450	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HNV93_RS12470	COG0438	transferase activity, transferring glycosyl groups
HNV93_RS12475	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HNV93_RS12485	COG0297	glycogen (starch) synthase activity
HNV93_RS12490	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HNV93_RS12495	COG3093	addiction module antidote protein HigA
HNV93_RS12510	COG0305	Participates in initiation and elongation during chromosome replication
HNV93_RS12515	COG0346	lactoylglutathione lyase activity
HNV93_RS12545	COG0745	RESPONSE REGULATOR receiver
HNV93_RS12550	COG5002	protein histidine kinase activity
HNV93_RS12555	COG4863	YycH protein
HNV93_RS12560	COG4853	Protein conserved in bacteria
HNV93_RS12565	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HNV93_RS12570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNV93_RS12575	COG0745	RESPONSE REGULATOR receiver
HNV93_RS12580	COG5002	protein histidine kinase activity
HNV93_RS12580	COG3850	Histidine kinase
HNV93_RS12585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HNV93_RS12600	COG0488	(ABC) transporter
HNV93_RS12610	COG3829	transcription factor binding
HNV93_RS12615	COG0640	Transcriptional regulator
HNV93_RS12620	COG5658	integral membrane protein
HNV93_RS12625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HNV93_RS12630	COG0833	amino acid
HNV93_RS12635	COG0010	Belongs to the arginase family
HNV93_RS12640	COG0457	Tetratricopeptide repeat
HNV93_RS12645	COG0456	acetyltransferase
HNV93_RS12650	COG0667	Aldo Keto reductase
HNV93_RS12655	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HNV93_RS12710	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HNV93_RS12715	COG2068	MobA-Related Protein
HNV93_RS12730	COG2080	2 iron, 2 sulfur cluster binding
HNV93_RS12740	COG1113	amino acid transport
HNV93_RS12745	COG3177	Filamentation induced by cAMP protein fic
HNV93_RS12750	COG3634	alkyl hydroperoxide reductase activity
HNV93_RS12755	COG0450	alkyl hydroperoxide reductase
HNV93_RS12765	COG1714	RDD family
HNV93_RS12770	COG2814	Major facilitator Superfamily
HNV93_RS12775	COG0640	Transcriptional regulator
HNV93_RS12785	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HNV93_RS12790	COG1012	belongs to the aldehyde dehydrogenase family
HNV93_RS12795	COG1309	transcriptional regulator
HNV93_RS12800	COG3239	Fatty acid desaturase
HNV93_RS12805	COG4585	Histidine kinase
HNV93_RS12810	COG2197	response regulator
HNV93_RS12815	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS12825	COG2814	Major facilitator Superfamily
HNV93_RS12830	COG0667	Aldo Keto reductase
HNV93_RS12835	COG1349	DNA-binding transcription factor activity
HNV93_RS12865	COG2814	Major facilitator Superfamily
HNV93_RS12875	COG1082	Xylose isomerase domain protein TIM barrel
HNV93_RS12905	COG0745	RESPONSE REGULATOR receiver
HNV93_RS12910	COG2205	protein histidine kinase activity
HNV93_RS12915	COG0745	RESPONSE REGULATOR receiver
HNV93_RS12920	COG2205	protein histidine kinase activity
HNV93_RS12925	COG1136	(ABC) transporter
HNV93_RS12930	COG0577	efflux transmembrane transporter activity
HNV93_RS12935	COG5294	Protein conserved in bacteria
HNV93_RS12940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HNV93_RS12970	COG0561	phosphatase activity
HNV93_RS12975	COG2390	Transcriptional regulator
HNV93_RS12985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HNV93_RS12990	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HNV93_RS12995	COG0833	amino acid
HNV93_RS13000	COG0010	Belongs to the arginase family
HNV93_RS13025	COG3507	Belongs to the glycosyl hydrolase 43 family
HNV93_RS13085	COG0589	response to stress
HNV93_RS13090	COG0697	spore germination
HNV93_RS13100	COG0513	Belongs to the DEAD box helicase family
HNV93_RS13105	COG2270	Major facilitator Superfamily
HNV93_RS13115	COG2273	Hydrolase Family 16
HNV93_RS13120	COG2851	Citrate transporter
HNV93_RS13125	COG0753	catalase activity
HNV93_RS13125	COG0693	protein deglycase activity
HNV93_RS13140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HNV93_RS13145	COG0500	methyltransferase
HNV93_RS13150	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HNV93_RS13155	COG4894	glucomannan catabolic process
HNV93_RS13170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HNV93_RS13180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNV93_RS13185	COG2508	Transcriptional regulator
HNV93_RS13190	COG3842	ATPase activity
HNV93_RS13195	COG0726	polysaccharide deacetylase
HNV93_RS13200	COG3493	citrate carrier protein
HNV93_RS13205	COG1271	oxidase subunit
HNV93_RS13210	COG1294	oxidase, subunit
HNV93_RS13215	COG4988	ABC transporter
HNV93_RS13220	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HNV93_RS13225	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HNV93_RS13245	COG3279	Response regulator of the LytR AlgR family
HNV93_RS13265	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HNV93_RS13270	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HNV93_RS13275	COG0753	catalase activity
HNV93_RS13285	COG1482	cell wall glycoprotein biosynthetic process
HNV93_RS13295	COG2723	6-phospho-beta-galactosidase activity
HNV93_RS13300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNV93_RS13305	COG1447	Phosphotransferase system cellobiose-specific component IIA
HNV93_RS13310	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNV93_RS13315	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HNV93_RS13320	COG0640	Transcriptional regulator
HNV93_RS13330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNV93_RS13335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNV93_RS13345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNV93_RS13345	COG3711	transcriptional antiterminator
HNV93_RS13350	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNV93_RS13355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNV93_RS13360	COG1447	Phosphotransferase system cellobiose-specific component IIA
HNV93_RS13365	COG1486	melibiose metabolic process
HNV93_RS13370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HNV93_RS13375	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HNV93_RS13385	COG1696	Membrane protein involved in D-alanine export
HNV93_RS13400	COG1575	Belongs to the MenA family. Type 1 subfamily
HNV93_RS13405	COG2357	RelA SpoT domain protein
HNV93_RS13410	COG1442	glycosyl transferase family 8
HNV93_RS13415	COG1404	Belongs to the peptidase S8 family
HNV93_RS13420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HNV93_RS13425	COG0346	lactoylglutathione lyase activity
HNV93_RS13430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HNV93_RS13435	COG5504	Zn-dependent protease
HNV93_RS13440	COG0789	Transcriptional regulator
HNV93_RS13445	COG4895	conserved protein (DUF2196)
HNV93_RS13450	COG1346	cytolysis
HNV93_RS13460	COG0583	DNA-binding transcription factor activity
HNV93_RS13480	COG2837	iron assimilation
HNV93_RS13485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HNV93_RS13505	COG1309	transcriptional regulator
HNV93_RS13510	COG2246	polysaccharide biosynthetic process
HNV93_RS13515	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HNV93_RS13520	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HNV93_RS13525	COG2261	transglycosylase associated protein
HNV93_RS13530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HNV93_RS13535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HNV93_RS13555	COG0454	-acetyltransferase
HNV93_RS13560	COG0772	Belongs to the SEDS family
HNV93_RS13565	COG0778	Nitroreductase
HNV93_RS13570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNV93_RS13575	COG1404	Belongs to the peptidase S8 family
HNV93_RS13585	COG3711	transcriptional antiterminator
HNV93_RS13590	COG1263	PTS System
HNV93_RS13590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HNV93_RS13595	COG1621	beta-fructofuranosidase activity
HNV93_RS13605	COG0351	phosphomethylpyrimidine kinase
HNV93_RS13610	COG1695	Transcriptional regulator
HNV93_RS13625	COG1216	Glycosyl transferase, family 2
HNV93_RS13640	COG2233	PERMEase
HNV93_RS13645	COG2363	Small membrane protein
HNV93_RS13655	COG0463	Glycosyl transferase, family 2
HNV93_RS13660	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HNV93_RS13665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HNV93_RS13670	COG0456	acetyltransferase
HNV93_RS13675	COG2089	acid synthase
HNV93_RS13680	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
HNV93_RS13685	COG3980	spore coat polysaccharide biosynthesis protein
HNV93_RS13690	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HNV93_RS13695	COG1088	dTDP-glucose 4,6-dehydratase activity
HNV93_RS13700	COG1091	dTDP-4-dehydrorhamnose reductase activity
HNV93_RS13705	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HNV93_RS13710	COG1131	(ABC) transporter
HNV93_RS13725	COG0745	RESPONSE REGULATOR receiver
HNV93_RS13730	COG2205	protein histidine kinase activity
HNV93_RS13735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HNV93_RS13740	COG1012	belongs to the aldehyde dehydrogenase family
HNV93_RS13745	COG4187	Peptidase family M20/M25/M40
HNV93_RS13750	COG0833	amino acid
HNV93_RS13755	COG2814	Major facilitator Superfamily
HNV93_RS13760	COG2814	Major facilitator Superfamily
HNV93_RS13790	COG0436	Aminotransferase
HNV93_RS13795	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS13805	COG0280	phosphate acetyltransferase
HNV93_RS13810	COG2855	membrane
HNV93_RS13815	COG0583	DNA-binding transcription factor activity
HNV93_RS13845	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HNV93_RS13850	COG1131	(ABC) transporter
HNV93_RS13860	COG1695	Transcriptional regulator
HNV93_RS13875	COG1078	dGTPase activity
HNV93_RS13880	COG3465	dGTPase activity
HNV93_RS13885	COG0531	amino acid
HNV93_RS13890	COG1846	Transcriptional regulator
HNV93_RS13895	COG1942	4-Oxalocrotonate Tautomerase
HNV93_RS13900	COG1994	Peptidase M50
HNV93_RS13915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HNV93_RS13920	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HNV93_RS13925	COG0010	Belongs to the arginase family
HNV93_RS13935	COG0457	Tetratricopeptide repeat
HNV93_RS13940	COG3391	amine dehydrogenase activity
HNV93_RS13945	COG3391	amine dehydrogenase activity
HNV93_RS13955	COG4506	Protein conserved in bacteria
HNV93_RS13965	COG2223	nitrite transmembrane transporter activity
HNV93_RS13970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HNV93_RS13980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HNV93_RS13985	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HNV93_RS13990	COG1140	nitrate reductase beta subunit
HNV93_RS13995	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HNV93_RS14000	COG2181	nitrate reductase activity
HNV93_RS14010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNV93_RS14015	COG1132	(ABC) transporter
HNV93_RS14030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNV93_RS14035	COG0247	lactate metabolic process
HNV93_RS14035	COG2181	nitrate reductase activity
HNV93_RS14050	COG4821	SIS domain
HNV93_RS14055	COG2204	response regulator
HNV93_RS14060	COG0191	fructose-bisphosphate aldolase activity
HNV93_RS14070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNV93_RS14075	COG1494	fructose-1,6-bisphosphatase
HNV93_RS14080	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HNV93_RS14095	COG0281	malic enzyme
HNV93_RS14100	COG0679	Auxin Efflux Carrier
HNV93_RS14105	COG0789	Transcriptional regulator
HNV93_RS14110	COG0346	lactoylglutathione lyase activity
HNV93_RS14115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HNV93_RS14120	COG2890	protein-(glutamine-N5) methyltransferase activity
HNV93_RS14140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HNV93_RS14145	COG0009	L-threonylcarbamoyladenylate synthase
HNV93_RS14155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNV93_RS14160	COG0698	ribose 5-phosphate isomerase
HNV93_RS14230	COG4836	Membrane
HNV93_RS14240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNV93_RS14245	COG2385	sporulation resulting in formation of a cellular spore
HNV93_RS14250	COG2304	oxidoreductase activity
HNV93_RS14255	COG2304	oxidoreductase activity
HNV93_RS14265	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HNV93_RS14275	COG0457	Tetratricopeptide repeat
HNV93_RS14280	COG1994	Peptidase M50
HNV93_RS14285	COG3237	CsbD-like
HNV93_RS14290	COG0831	urea catabolic process
HNV93_RS14305	COG1959	2 iron, 2 sulfur cluster binding
HNV93_RS14315	COG0726	polysaccharide deacetylase
HNV93_RS14325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNV93_RS14340	COG1247	-acetyltransferase
HNV93_RS14345	COG0739	heme binding
HNV93_RS14355	COG0671	phosphoesterase, PA-phosphatase related
HNV93_RS14360	COG0772	Belongs to the SEDS family
HNV93_RS14365	COG0347	Belongs to the P(II) protein family
HNV93_RS14370	COG0004	ammonium transporteR
HNV93_RS14375	COG1335	isochorismatase
HNV93_RS14380	COG0477	Major facilitator Superfamily
HNV93_RS14385	COG1953	Uracil, thiamine, allantoin
HNV93_RS14390	COG2814	Major facilitator Superfamily
HNV93_RS14395	COG1846	Transcriptional regulator
HNV93_RS14400	COG1609	Transcriptional regulator
HNV93_RS14405	COG1077	Cell shape determining protein MreB Mrl
HNV93_RS14410	COG4786	Flagellar basal body rod
HNV93_RS14415	COG4786	Flagellar basal body rod
HNV93_RS14420	COG0457	Tetratricopeptide repeat
HNV93_RS14445	COG0629	single-stranded DNA binding
HNV93_RS14450	COG1349	DNA-binding transcription factor activity
HNV93_RS14455	COG0561	phosphatase activity
HNV93_RS14460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HNV93_RS14465	COG4715	Zinc finger, swim domain protein
HNV93_RS14475	COG3944	biosynthesis protein
HNV93_RS14480	COG0489	protein tyrosine kinase activity
HNV93_RS14485	COG4464	protein tyrosine phosphatase activity
HNV93_RS14490	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HNV93_RS14495	COG3878	Protein conserved in bacteria
HNV93_RS14510	COG5444	nuclease activity
HNV93_RS14535	COG0583	DNA-binding transcription factor activity
HNV93_RS14540	COG0655	NAD(P)H dehydrogenase (quinone) activity
HNV93_RS14550	COG2059	Chromate
HNV93_RS14555	COG2059	Chromate
HNV93_RS14560	COG1522	sequence-specific DNA binding
HNV93_RS14565	COG0405	Gamma-glutamyltransferase
HNV93_RS14575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HNV93_RS14585	COG5337	Spore coat protein CotH
HNV93_RS14600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HNV93_RS14605	COG0583	DNA-binding transcription factor activity
HNV93_RS14610	COG0028	Belongs to the TPP enzyme family
HNV93_RS14615	COG3527	Alpha-acetolactate decarboxylase
HNV93_RS14620	COG2249	NAD(P)H dehydrogenase (quinone) activity
HNV93_RS14625	COG3103	Sh3 type 3 domain protein
HNV93_RS14630	COG1879	ABC-type sugar transport system periplasmic component
HNV93_RS14635	COG1172	Belongs to the binding-protein-dependent transport system permease family
HNV93_RS14640	COG1129	ABC transporter
HNV93_RS14650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HNV93_RS14655	COG1609	Transcriptional regulator
HNV93_RS14665	COG0814	amino acid
HNV93_RS14670	COG0697	spore germination
HNV93_RS14675	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HNV93_RS14685	COG2843	Capsule synthesis protein
HNV93_RS14695	COG0791	NLP P60 protein
HNV93_RS14700	COG2433	Pfam Transposase IS66
HNV93_RS14705	COG0561	phosphatase activity
HNV93_RS14710	COG1316	TRANSCRIPTIONal
HNV93_RS14715	COG2814	Major facilitator Superfamily
HNV93_RS14720	COG1215	transferase activity, transferring glycosyl groups
HNV93_RS14730	COG0814	amino acid
HNV93_RS14735	COG0697	spore germination
HNV93_RS14740	COG1482	cell wall glycoprotein biosynthetic process
HNV93_RS14745	COG4193	domain, Protein
HNV93_RS14750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HNV93_RS14755	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HNV93_RS14760	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HNV93_RS14770	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HNV93_RS14775	COG1682	transport, permease protein
HNV93_RS14780	COG1134	teichoic acid transport
HNV93_RS14785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HNV93_RS14790	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HNV93_RS14795	COG1316	TRANSCRIPTIONal
HNV93_RS14805	COG2385	sporulation resulting in formation of a cellular spore
HNV93_RS14805	COG2247	cell wall binding repeat
HNV93_RS14810	COG2247	cell wall binding repeat
HNV93_RS14810	COG0860	N-Acetylmuramoyl-L-alanine amidase
HNV93_RS14820	COG2244	polysaccharide biosynthetic process
HNV93_RS14825	COG0297	glycogen (starch) synthase activity
HNV93_RS14825	COG0438	transferase activity, transferring glycosyl groups
HNV93_RS14830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HNV93_RS14835	COG3307	-O-antigen
HNV93_RS14840	COG3206	protein involved in exopolysaccharide biosynthesis
HNV93_RS14845	COG1215	transferase activity, transferring glycosyl groups
HNV93_RS14850	COG0438	transferase activity, transferring glycosyl groups
HNV93_RS14855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HNV93_RS14860	COG1316	TRANSCRIPTIONal
HNV93_RS14865	COG1739	Uncharacterized protein family UPF0029
HNV93_RS14870	COG4585	Histidine kinase
HNV93_RS14875	COG2197	response regulator
HNV93_RS14880	COG1307	EDD domain protein, DegV family
HNV93_RS14885	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HNV93_RS14895	COG1040	competence protein
HNV93_RS14905	COG2747	anti-sigma28 factor FlgM
HNV93_RS14910	COG3418	PFAM FlgN family protein
HNV93_RS14915	COG1256	bacterial-type flagellum assembly
HNV93_RS14915	COG4786	Flagellar basal body rod
HNV93_RS14920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HNV93_RS14940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HNV93_RS14945	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HNV93_RS14950	COG1516	flagellar protein fliS
HNV93_RS14965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HNV93_RS14980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HNV93_RS14985	COG2010	Cytochrome c
HNV93_RS14990	COG2884	Cell division ATP-binding protein ftsE
HNV93_RS14995	COG2177	Part of the ABC transporter FtsEX involved in
HNV93_RS15000	COG3420	alginic acid biosynthetic process
HNV93_RS15005	COG3409	Peptidoglycan-binding domain 1 protein
HNV93_RS15005	COG0793	Belongs to the peptidase S41A family
HNV93_RS15015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNV93_RS15030	COG2814	Major facilitator Superfamily
HNV93_RS15035	COG1309	transcriptional regulator
HNV93_RS15040	COG0574	Belongs to the PEP-utilizing enzyme family
HNV93_RS15040	COG3848	Pyruvate phosphate dikinase
HNV93_RS15045	COG4897	Protein conserved in bacteria
HNV93_RS15055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HNV93_RS15070	COG3595	metallopeptidase activity
HNV93_RS15075	COG1983	PspC domain protein
HNV93_RS15080	COG1950	PFAM Membrane protein of
HNV93_RS15085	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HNV93_RS15090	COG1309	transcriptional regulator
HNV93_RS15095	COG2188	Transcriptional regulator
HNV93_RS15105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HNV93_RS15125	COG0110	maltose O-acetyltransferase activity
HNV93_RS15130	COG4990	cell redox homeostasis
HNV93_RS15145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HNV93_RS15170	COG0140	phosphoribosyl-ATP diphosphatase activity
HNV93_RS15170	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HNV93_RS15175	COG1132	(ABC) transporter
HNV93_RS15180	COG0745	RESPONSE REGULATOR receiver
HNV93_RS15185	COG5002	protein histidine kinase activity
HNV93_RS15190	COG0457	Tetratricopeptide repeat
HNV93_RS15195	COG0791	NLP P60 protein
HNV93_RS15195	COG3883	PFAM NLP P60 protein
HNV93_RS15200	COG0492	ferredoxin-NADP+ reductase activity
HNV93_RS15205	COG1051	belongs to the nudix hydrolase family
HNV93_RS15215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HNV93_RS15225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNV93_RS15230	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HNV93_RS15235	COG4290	ribonuclease
HNV93_RS15240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNV93_RS15245	COG0288	reversible hydration of carbon dioxide
HNV93_RS15250	COG0659	secondary active sulfate transmembrane transporter activity
HNV93_RS15255	COG1694	Mazg nucleotide pyrophosphohydrolase
HNV93_RS15260	COG1611	Belongs to the LOG family
HNV93_RS15265	COG1609	Transcriptional regulator
HNV93_RS15270	COG0366	Alpha amylase catalytic
HNV93_RS15275	COG2182	Extracellular solute-binding protein
HNV93_RS15280	COG1175	transmembrane transport
HNV93_RS15285	COG3833	ABC-type maltose transport systems, permease component
HNV93_RS15290	COG5521	maltodextrose utilization protein MalA
HNV93_RS15295	COG1554	hydrolase, family 65, central catalytic
HNV93_RS15300	COG0366	Alpha amylase catalytic
HNV93_RS15305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HNV93_RS15315	COG1609	Transcriptional regulator
HNV93_RS15320	COG2223	nitrite transmembrane transporter activity
HNV93_RS15370	COG3479	Phenolic acid decarboxylase
HNV93_RS15375	COG0456	acetyltransferase
HNV93_RS15380	COG2364	Membrane
HNV93_RS15385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HNV93_RS15390	COG2272	Belongs to the type-B carboxylesterase lipase family
HNV93_RS15395	COG1396	sequence-specific DNA binding
HNV93_RS15400	COG3944	biosynthesis protein
HNV93_RS15405	COG0489	protein tyrosine kinase activity
HNV93_RS15410	COG1086	Polysaccharide biosynthesis protein
HNV93_RS15415	COG0438	transferase activity, transferring glycosyl groups
HNV93_RS15420	COG1215	transferase activity, transferring glycosyl groups
HNV93_RS15425	COG0438	transferase activity, transferring glycosyl groups
HNV93_RS15435	COG1216	Glycosyl transferase, family 2
HNV93_RS15440	COG5039	Polysaccharide pyruvyl transferase
HNV93_RS15445	COG1216	Glycosyl transferase, family 2
HNV93_RS15450	COG2244	polysaccharide biosynthetic process
HNV93_RS15455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HNV93_RS15460	COG0110	maltose O-acetyltransferase activity
HNV93_RS15465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HNV93_RS15470	COG5039	Polysaccharide pyruvyl transferase
HNV93_RS15480	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HNV93_RS15485	COG1620	l-lactate permease
HNV93_RS15490	COG2186	Transcriptional regulator
HNV93_RS15495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNV93_RS15535	COG1070	Carbohydrate kinase
HNV93_RS15540	COG1737	Transcriptional regulator
HNV93_RS15545	COG0561	phosphatase activity
HNV93_RS15555	COG1609	Transcriptional regulator
HNV93_RS15560	COG1113	amino acid transport
HNV93_RS15565	COG0697	spore germination
HNV93_RS15570	COG0583	DNA-binding transcription factor activity
HNV93_RS15580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNV93_RS15585	COG1609	Transcriptional regulator
HNV93_RS15590	COG2814	Major facilitator Superfamily
HNV93_RS15595	COG2390	Transcriptional regulator
HNV93_RS15600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HNV93_RS15605	COG0126	phosphoglycerate kinase activity
HNV93_RS15625	COG2234	aminopeptidase activity
HNV93_RS15635	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HNV93_RS15640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNV93_RS15660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HNV93_RS15675	COG0456	acetyltransferase
HNV93_RS15680	COG4640	response to antibiotic
HNV93_RS15685	COG3064	Membrane
HNV93_RS15690	COG2095	MarC family integral membrane protein
HNV93_RS15695	COG1510	regulation of RNA biosynthetic process
HNV93_RS15700	COG1125	glycine betaine transport
HNV93_RS15700	COG0517	IMP dehydrogenase activity
HNV93_RS15705	COG1174	glycine betaine transport
HNV93_RS15710	COG1732	Glycine betaine
HNV93_RS15715	COG1174	glycine betaine transport
HNV93_RS15720	COG1510	regulation of RNA biosynthetic process
HNV93_RS15725	COG1125	glycine betaine transport
HNV93_RS15725	COG0517	IMP dehydrogenase activity
HNV93_RS15730	COG1174	glycine betaine transport
HNV93_RS15735	COG1732	Glycine betaine
HNV93_RS15740	COG1174	glycine betaine transport
HNV93_RS15745	COG1131	(ABC) transporter
HNV93_RS15770	COG1733	regulation of RNA biosynthetic process
HNV93_RS15775	COG1396	sequence-specific DNA binding
HNV93_RS15780	COG1396	sequence-specific DNA binding
HNV93_RS15785	COG1476	TRANSCRIPTIONal
HNV93_RS15790	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HNV93_RS15795	COG1647	Serine aminopeptidase, S33
HNV93_RS15800	COG0557	exoribonuclease II activity
HNV93_RS15840	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS15845	COG0583	DNA-binding transcription factor activity
HNV93_RS15850	COG0454	-acetyltransferase
HNV93_RS15855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNV93_RS15860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNV93_RS15865	COG0765	amino acid transport
HNV93_RS15870	COG0765	amino acid transport
HNV93_RS15875	COG1126	abc transporter atp-binding protein
HNV93_RS15880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNV93_RS15885	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HNV93_RS15890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNV93_RS15900	COG0673	inositol 2-dehydrogenase activity
HNV93_RS15905	COG1937	Protein conserved in bacteria
HNV93_RS15910	COG2608	mercury ion transmembrane transporter activity
HNV93_RS15915	COG2217	Heavy metal translocating P-type atpase
HNV93_RS15920	COG2217	Heavy metal translocating P-type atpase
HNV93_RS15925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HNV93_RS15930	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HNV93_RS15940	COG2860	membrane
HNV93_RS15945	COG3973	AAA domain
HNV93_RS15950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HNV93_RS15970	COG0656	L-ascorbic acid biosynthetic process
HNV93_RS15975	COG0842	Transport permease protein
HNV93_RS15985	COG1131	(ABC) transporter
HNV93_RS15990	COG3850	Histidine kinase
HNV93_RS15995	COG2197	response regulator
HNV93_RS16000	COG4149	molybdate abc transporter
HNV93_RS16005	COG0725	ABC transporter, periplasmic molybdate-binding protein
HNV93_RS16010	COG1910	domain protein
HNV93_RS16015	COG1368	sulfuric ester hydrolase activity
HNV93_RS16020	COG1988	membrane-bound metal-dependent
HNV93_RS16030	COG0531	amino acid
HNV93_RS16035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HNV93_RS16040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNV93_RS16045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNV93_RS16050	COG1120	ATPase activity
HNV93_RS16060	COG2140	Oxalate decarboxylase
HNV93_RS16070	COG1191	sigma factor activity
HNV93_RS16080	COG0745	RESPONSE REGULATOR receiver
HNV93_RS16085	COG2205	protein histidine kinase activity
HNV93_RS16090	COG3386	PFAM SMP-30 Gluconolaconase
HNV93_RS16095	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS16100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HNV93_RS16105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNV93_RS16110	COG1120	ATPase activity
HNV93_RS16115	COG2096	Adenosyltransferase
HNV93_RS16120	COG2814	Major facilitator Superfamily
HNV93_RS16125	COG4758	membrane
HNV93_RS16130	COG1842	Phage shock protein A
HNV93_RS16135	COG3595	metallopeptidase activity
HNV93_RS16140	COG4758	membrane
HNV93_RS16145	COG4585	Histidine kinase
HNV93_RS16150	COG2197	response regulator
HNV93_RS16160	COG0814	amino acid
HNV93_RS16165	COG0697	spore germination
HNV93_RS16175	COG0114	fumarate hydratase activity
HNV93_RS16180	COG1309	transcriptional regulator
HNV93_RS16190	COG2205	protein histidine kinase activity
HNV93_RS16190	COG2770	Histidine kinase
HNV93_RS16195	COG0745	RESPONSE REGULATOR receiver
HNV93_RS16200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNV93_RS16205	COG0783	Belongs to the Dps family
HNV93_RS16210	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS16225	COG1120	ATPase activity
HNV93_RS16245	COG0583	DNA-binding transcription factor activity
HNV93_RS16255	COG0583	DNA-binding transcription factor activity
HNV93_RS16260	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS16265	COG1942	4-Oxalocrotonate Tautomerase
HNV93_RS16270	COG0477	Major facilitator Superfamily
HNV93_RS16275	COG1846	Transcriptional regulator
HNV93_RS16280	COG5577	PFAM Coat F domain
HNV93_RS16300	COG1024	Enoyl-CoA hydratase
HNV93_RS16300	COG1250	3-hydroxyacyl-CoA dehydrogenase
HNV93_RS16305	COG0183	Belongs to the thiolase family
HNV93_RS16310	COG1960	acyl-CoA dehydrogenase activity
HNV93_RS16315	COG1393	Belongs to the ArsC family
HNV93_RS16330	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HNV93_RS16335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNV93_RS16345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HNV93_RS16350	COG2011	ABC-type metal ion transport system permease component
HNV93_RS16355	COG1464	Belongs to the NlpA lipoprotein family
HNV93_RS16360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HNV93_RS16370	COG0396	ATPase activity
HNV93_RS16375	COG0719	Fe-S assembly protein
HNV93_RS16380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HNV93_RS16385	COG0822	iron-sulfur transferase activity
HNV93_RS16390	COG0719	Fe-S assembly protein
HNV93_RS16395	COG3409	Peptidoglycan-binding domain 1 protein
HNV93_RS16415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNV93_RS16420	COG0322	excinuclease ABC activity
HNV93_RS16445	COG0789	Transcriptional regulator
HNV93_RS16450	COG2222	sugar isomerase
HNV93_RS16455	COG1653	transport
HNV93_RS16460	COG1175	transmembrane transport
HNV93_RS16465	COG0395	ABC-type sugar transport system, permease component
HNV93_RS16470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HNV93_RS16475	COG2188	Transcriptional regulator
HNV93_RS16480	COG3842	ATPase activity
HNV93_RS16485	COG2356	endonuclease I
HNV93_RS16490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HNV93_RS16495	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HNV93_RS16500	COG2814	Major facilitator Superfamily
HNV93_RS16520	COG2508	Transcriptional regulator
HNV93_RS16535	COG1801	Protein of unknown function DUF72
HNV93_RS16540	COG0730	response to heat
HNV93_RS16545	COG0737	Belongs to the 5'-nucleotidase family
HNV93_RS16555	COG0739	heme binding
HNV93_RS16565	COG4470	Protein conserved in bacteria
HNV93_RS16570	COG2445	Protein of unknown function DUF86
HNV93_RS16575	COG0647	UMP catabolic process
HNV93_RS16580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HNV93_RS16585	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HNV93_RS16590	COG0460	homoserine dehydrogenase
HNV93_RS16595	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HNV93_RS16605	COG4946	Tricorn protease homolog
HNV93_RS16605	COG1506	peptidase
HNV93_RS16605	COG0823	Involved in the tonB-independent uptake of proteins
HNV93_RS16610	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HNV93_RS16615	COG4837	Protein of unknown function (DUF1462)
HNV93_RS16620	COG1252	NADH dehydrogenase
HNV93_RS16630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HNV93_RS16640	COG0316	Belongs to the HesB IscA family
HNV93_RS16645	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
HNV93_RS16650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HNV93_RS16670	COG1131	(ABC) transporter
HNV93_RS16700	COG1252	NADH dehydrogenase
HNV93_RS16715	COG3584	3D domain protein
HNV93_RS16720	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HNV93_RS16730	COG2056	Na+-H+ antiporter family
HNV93_RS16735	COG1268	BioY protein
HNV93_RS16740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HNV93_RS16745	COG2819	hydrolase of the alpha beta superfamily
HNV93_RS16750	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS16755	COG1169	isochorismate synthase
HNV93_RS16760	COG1021	2,3-dihydroxybenzoate-AMP ligase
HNV93_RS16765	COG1535	isochorismatase
HNV93_RS16765	COG3433	isochorismatase activity
HNV93_RS16770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNV93_RS16775	COG3251	PFAM MbtH domain protein
HNV93_RS16780	COG5634	Uncharacterized conserved protein (DUF2278)
HNV93_RS16785	COG0686	Belongs to the AlaDH PNT family
HNV93_RS16790	COG2508	Transcriptional regulator
HNV93_RS16790	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HNV93_RS16795	COG4842	Belongs to the WXG100 family
HNV93_RS16800	COG5417	Belongs to the EsaB family
HNV93_RS16805	COG4499	WXG100 protein secretion system (Wss), protein YukC
HNV93_RS16810	COG1674	ftsk spoiiie
HNV93_RS16810	COG0433	COG0433 Predicted ATPase
HNV93_RS16815	COG1511	domain protein
HNV93_RS16825	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS16830	COG1418	mRNA catabolic process
HNV93_RS16840	COG0628	permease
HNV93_RS16855	COG5506	Protein of unknown function (DUF1694)
HNV93_RS16860	COG1335	isochorismatase
HNV93_RS16865	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HNV93_RS16870	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HNV93_RS16905	COG2197	response regulator
HNV93_RS16910	COG2050	protein possibly involved in aromatic compounds catabolism
HNV93_RS16915	COG1320	monovalent cation:proton antiporter activity
HNV93_RS16920	COG2212	antiporter activity
HNV93_RS16925	COG1863	multisubunit Na H antiporter MnhE subunit
HNV93_RS16930	COG0651	ATP synthesis coupled electron transport
HNV93_RS16935	COG1006	Multisubunit Na H antiporter MnhC subunit
HNV93_RS16940	COG2111	Na H antiporter
HNV93_RS16945	COG2111	Na H antiporter
HNV93_RS16945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HNV93_RS16975	COG4565	transcriptional regulatory protein
HNV93_RS16980	COG3290	protein histidine kinase activity
HNV93_RS16990	COG3011	Protein conserved in bacteria
HNV93_RS16995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HNV93_RS17000	COG2814	Major facilitator Superfamily
HNV93_RS17005	COG5018	Exonuclease
HNV93_RS17015	COG2205	protein histidine kinase activity
HNV93_RS17020	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HNV93_RS17030	COG2267	carboxylic ester hydrolase activity
HNV93_RS17035	COG1522	sequence-specific DNA binding
HNV93_RS17040	COG0436	Aminotransferase
HNV93_RS17045	COG1098	S1 RNA binding domain
HNV93_RS17050	COG2155	Conserved Protein
HNV93_RS17055	COG1979	alcohol dehydrogenase
HNV93_RS17060	COG1979	alcohol dehydrogenase
HNV93_RS17065	COG1335	isochorismatase
HNV93_RS17090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HNV93_RS17105	COG2738	Putative neutral zinc metallopeptidase
HNV93_RS17110	COG1253	flavin adenine dinucleotide binding
HNV93_RS17115	COG0366	Alpha amylase catalytic
HNV93_RS17120	COG0432	Pfam Uncharacterised protein family UPF0047
HNV93_RS17125	COG2070	2-Nitropropane dioxygenase
HNV93_RS17140	COG0840	transmembrane signaling receptor activity
HNV93_RS17145	COG0840	transmembrane signaling receptor activity
HNV93_RS17150	COG0840	transmembrane signaling receptor activity
HNV93_RS17155	COG0840	transmembrane signaling receptor activity
HNV93_RS17160	COG0693	protein deglycase activity
HNV93_RS17165	COG0673	inositol 2-dehydrogenase activity
HNV93_RS17170	COG0628	permease
HNV93_RS17195	COG1017	nitric oxide dioxygenase activity
HNV93_RS17195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HNV93_RS17200	COG1705	Flagellar rod assembly protein muramidase FlgJ
HNV93_RS17205	COG0569	domain protein
HNV93_RS17215	COG1510	regulation of RNA biosynthetic process
HNV93_RS17220	COG1012	belongs to the aldehyde dehydrogenase family
HNV93_RS17225	COG1454	alcohol dehydrogenase
HNV93_RS17235	COG2318	DinB family
HNV93_RS17240	COG1585	Membrane protein implicated in regulation of membrane protease activity
HNV93_RS17245	COG2268	Band 7 protein
HNV93_RS17250	COG3859	Proton-coupled thiamine transporter YuaJ
HNV93_RS17375	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
HNV93_RS17380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HNV93_RS17385	COG1169	isochorismate synthase
HNV93_RS17395	COG0596	Alpha beta hydrolase
HNV93_RS17400	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HNV93_RS17410	COG4948	Mandelate Racemase Muconate Lactonizing
HNV93_RS17425	COG1294	oxidase, subunit
HNV93_RS17430	COG1271	oxidase subunit
HNV93_RS17440	COG0288	reversible hydration of carbon dioxide
HNV93_RS17465	COG0783	Belongs to the Dps family
HNV93_RS17470	COG4824	toxin secretion phage lysis holin
HNV93_RS17475	COG0494	nUDIX hydrolase
HNV93_RS17480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HNV93_RS17485	COG1116	anion transmembrane transporter activity
HNV93_RS17490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HNV93_RS17495	COG1506	peptidase
HNV93_RS17515	COG0367	asparagine synthase
HNV93_RS17520	COG1113	amino acid transport
HNV93_RS17525	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HNV93_RS17530	COG2267	carboxylic ester hydrolase activity
HNV93_RS17540	COG0584	glycerophosphoryl diester phosphodiesterase
HNV93_RS17550	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HNV93_RS17555	COG1242	4 iron, 4 sulfur cluster binding
HNV93_RS17565	COG1725	Transcriptional regulator
HNV93_RS17570	COG1131	(ABC) transporter
HNV93_RS17590	COG1136	(ABC) transporter
HNV93_RS17595	COG0577	efflux transmembrane transporter activity
HNV93_RS17600	COG0745	RESPONSE REGULATOR receiver
HNV93_RS17605	COG2205	protein histidine kinase activity
HNV93_RS17610	COG1136	(ABC) transporter
HNV93_RS17615	COG0577	efflux transmembrane transporter activity
HNV93_RS17620	COG5522	Integral membrane protein (intg_mem_TP0381)
HNV93_RS17625	COG2814	Major facilitator Superfamily
HNV93_RS17630	COG2202	Pas domain
HNV93_RS17630	COG1366	Belongs to the anti-sigma-factor antagonist family
HNV93_RS17645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNV93_RS17655	COG1486	melibiose metabolic process
HNV93_RS17660	COG0395	ABC-type sugar transport system, permease component
HNV93_RS17665	COG1175	transmembrane transport
HNV93_RS17670	COG1653	transport
HNV93_RS17675	COG1609	Transcriptional regulator
HNV93_RS17685	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HNV93_RS17690	COG2081	HI0933 family
HNV93_RS17695	COG2244	polysaccharide biosynthetic process
HNV93_RS17700	COG1187	pseudouridine synthase activity
HNV93_RS17705	COG1349	DNA-binding transcription factor activity
HNV93_RS17710	COG1131	(ABC) transporter
HNV93_RS17715	COG4473	ABC transporter
HNV93_RS17720	COG2252	PERMEase
HNV93_RS17725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HNV93_RS17730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HNV93_RS17735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HNV93_RS17745	COG1597	lipid kinase activity
HNV93_RS17750	COG0510	thiamine kinase activity
HNV93_RS17765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNV93_RS17770	COG0281	malic enzyme
HNV93_RS17775	COG5584	Small secreted protein
HNV93_RS17780	COG1363	Peptidase, m42
HNV93_RS17790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNV93_RS17800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNV93_RS17805	COG1674	ftsk spoiiie
HNV93_RS17815	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HNV93_RS17820	COG4980	gas vesicle protein
HNV93_RS17825	COG3118	belongs to the thioredoxin family
HNV93_RS17830	COG1605	Chorismate mutase
HNV93_RS17830	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HNV93_RS17835	COG1609	Transcriptional regulator
HNV93_RS17840	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HNV93_RS17845	COG1360	Flagellar Motor Protein
HNV93_RS17850	COG0123	including yeast histone deacetylase and acetoin utilization protein
HNV93_RS17855	COG0517	IMP dehydrogenase activity
HNV93_RS17860	COG0454	-acetyltransferase
HNV93_RS17865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HNV93_RS17885	COG1378	Sugar-specific transcriptional regulator TrmB
HNV93_RS17890	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HNV93_RS17905	COG0693	protein deglycase activity
HNV93_RS17920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HNV93_RS17920	COG1017	nitric oxide dioxygenase activity
HNV93_RS17965	COG4282	regulation of fungal-type cell wall biogenesis
HNV93_RS17970	COG1012	belongs to the aldehyde dehydrogenase family
HNV93_RS17980	COG2199	diguanylate cyclase activity
HNV93_RS17980	COG2203	Gaf domain
HNV93_RS17985	COG1956	GAF domain-containing protein
HNV93_RS17990	COG1309	transcriptional regulator
HNV93_RS17995	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HNV93_RS18005	COG1114	Component of the transport system for branched-chain amino acids
HNV93_RS18010	COG1104	cysteine desulfurase activity
HNV93_RS18025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HNV93_RS18030	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HNV93_RS18035	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNV93_RS18040	COG0616	signal peptide processing
HNV93_RS18045	COG1714	RDD family
HNV93_RS18055	COG3874	Sporulation protein YtfJ
HNV93_RS18060	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HNV93_RS18065	COG0827	DNA restriction-modification system
HNV93_RS18075	COG0521	Mo-molybdopterin cofactor biosynthetic process
HNV93_RS18090	COG1028	Short-chain dehydrogenase reductase Sdr
HNV93_RS18100	COG4109	DRTGG domain
HNV93_RS18110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HNV93_RS18130	COG0587	DNA-directed DNA polymerase activity
HNV93_RS18135	COG0281	malic enzyme
HNV93_RS18155	COG0469	pyruvate kinase activity
HNV93_RS18160	COG3030	protein affecting phage T7 exclusion by the F plasmid
HNV93_RS18165	COG0628	permease
HNV93_RS18195	COG0372	Belongs to the citrate synthase family
HNV93_RS18200	COG0538	isocitrate dehydrogenase activity
HNV93_RS18210	COG0745	RESPONSE REGULATOR receiver
HNV93_RS18215	COG5002	protein histidine kinase activity
HNV93_RS18220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HNV93_RS18220	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HNV93_RS18225	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HNV93_RS18230	COG1971	Probably functions as a manganese efflux pump
HNV93_RS18235	COG0237	dephospho-CoA kinase activity
HNV93_RS18240	COG0656	L-ascorbic acid biosynthetic process
HNV93_RS18245	COG2814	Major facilitator Superfamily
HNV93_RS18250	COG1733	regulation of RNA biosynthetic process
HNV93_RS18255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HNV93_RS18270	COG3611	Membrane attachment protein
HNV93_RS18275	COG1484	DNA-dependent DNA replication
HNV93_RS18280	COG0398	Pfam SNARE associated Golgi protein
HNV93_RS18295	COG1011	Hydrolase
HNV93_RS18300	COG3275	phosphorelay sensor kinase activity
HNV93_RS18305	COG3279	Response regulator of the LytR AlgR family
HNV93_RS18310	COG1380	Effector of murein hydrolase LrgA
HNV93_RS18315	COG1346	cytolysis
HNV93_RS18320	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HNV93_RS18335	COG3326	Membrane
HNV93_RS18345	COG1363	Peptidase, m42
HNV93_RS18350	COG3507	Belongs to the glycosyl hydrolase 43 family
HNV93_RS18355	COG2160	L-arabinose isomerase activity
HNV93_RS18360	COG1069	ribulokinase activity
HNV93_RS18365	COG0235	Class ii aldolase
HNV93_RS18370	COG0647	UMP catabolic process
HNV93_RS18380	COG1653	transport
HNV93_RS18385	COG1175	transmembrane transport
HNV93_RS18390	COG0395	ABC-type sugar transport system, permease component
HNV93_RS18395	COG3534	alpha-L-arabinofuranosidase
HNV93_RS18400	COG1966	Carbon starvation protein
HNV93_RS18405	COG0247	lactate metabolic process
HNV93_RS18410	COG0277	FAD linked oxidase domain protein
HNV93_RS18415	COG3835	regulator
HNV93_RS18425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNV93_RS18430	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HNV93_RS18435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNV93_RS18435	COG0072	phenylalanine-tRNA ligase activity
HNV93_RS18450	COG1286	toxin biosynthetic process
HNV93_RS18455	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HNV93_RS18455	COG1796	DNA polymerase
HNV93_RS18465	COG3766	membrane
HNV93_RS18475	COG0318	PFAM AMP-dependent synthetase and ligase
HNV93_RS18480	COG1309	transcriptional regulator
HNV93_RS18485	COG1024	Enoyl-CoA hydratase
HNV93_RS18490	COG2086	electron transfer activity
HNV93_RS18495	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HNV93_RS18500	COG3534	alpha-L-arabinofuranosidase
HNV93_RS18505	COG3118	belongs to the thioredoxin family
HNV93_RS18515	COG0527	aspartate kinase activity
HNV93_RS18520	COG1719	4-vinyl reductase, 4VR
HNV93_RS18525	COG2009	succinate dehydrogenase
HNV93_RS18530	COG1053	succinate dehydrogenase
HNV93_RS18535	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HNV93_RS18540	COG0824	Thioesterase
HNV93_RS18545	COG2197	response regulator
HNV93_RS18550	COG1846	Transcriptional regulator
HNV93_RS18560	COG5401	PFAM Sporulation and spore germination
HNV93_RS18570	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HNV93_RS18575	COG0622	Phosphoesterase
HNV93_RS18600	COG0028	Belongs to the TPP enzyme family
HNV93_RS18605	COG0440	acetolactate synthase activity
HNV93_RS18620	COG0473	3-isopropylmalate dehydrogenase activity
HNV93_RS18635	COG0457	Tetratricopeptide repeat
HNV93_RS18635	COG1477	protein flavinylation
HNV93_RS18650	COG0470	DNA polymerase III
HNV93_RS18650	COG1067	ATP-dependent peptidase activity
HNV93_RS18655	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HNV93_RS18675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HNV93_RS18685	COG1587	Uroporphyrinogen-III synthase
HNV93_RS18690	COG0113	porphobilinogen synthase activity
HNV93_RS18700	COG1388	LysM domain
HNV93_RS18705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HNV93_RS18715	COG0525	valine-tRNA ligase activity
HNV93_RS18720	COG0285	dihydrofolate synthase activity
HNV93_RS18725	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HNV93_RS18745	COG1077	Cell shape determining protein MreB Mrl
HNV93_RS18755	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HNV93_RS18760	COG0850	regulation of cytokinetic process
HNV93_RS18765	COG2894	cell division
HNV93_RS18770	COG0739	heme binding
HNV93_RS18775	COG1994	Peptidase M50
HNV93_RS18785	COG2868	ribosomal protein
HNV93_RS18790	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HNV93_RS18795	COG3290	protein histidine kinase activity
HNV93_RS18810	COG0077	Prephenate dehydratase
HNV93_RS18815	COG1827	regulation of RNA biosynthetic process
HNV93_RS18820	COG1104	cysteine desulfurase activity
HNV93_RS18825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HNV93_RS18830	COG0157	Belongs to the NadC ModD family
HNV93_RS18840	COG1388	LysM domain
HNV93_RS18880	COG1862	Preprotein translocase
HNV93_RS18890	COG2323	membrane
HNV93_RS18895	COG2244	polysaccharide biosynthetic process
HNV93_RS18905	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HNV93_RS18905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HNV93_RS18910	COG0490	domain, Protein
HNV93_RS18915	COG5416	Lipopolysaccharide assembly protein A domain
HNV93_RS18920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HNV93_RS18920	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HNV93_RS18930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HNV93_RS18940	COG4991	sh3 domain protein
HNV93_RS18940	COG0860	N-Acetylmuramoyl-L-alanine amidase
HNV93_RS18940	COG3103	Sh3 type 3 domain protein
HNV93_RS18965	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HNV93_RS18970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HNV93_RS18975	COG1959	2 iron, 2 sulfur cluster binding
HNV93_RS18980	COG1104	cysteine desulfurase activity
HNV93_RS18990	COG0457	Tetratricopeptide repeat
HNV93_RS18995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HNV93_RS19000	COG3881	PFAM PRC-barrel domain
HNV93_RS19015	COG0765	amino acid transport
HNV93_RS19020	COG0765	amino acid transport
HNV93_RS19025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNV93_RS19030	COG1126	abc transporter atp-binding protein
HNV93_RS19035	COG0628	permease
HNV93_RS19060	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HNV93_RS19065	COG4122	O-methyltransferase activity
HNV93_RS19090	COG0768	penicillin binding
HNV93_RS19115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HNV93_RS19120	COG0626	cystathionine gamma-synthase activity
HNV93_RS19130	COG2427	Protein of unknown function (DUF1641)
HNV93_RS19135	COG3383	formate dehydrogenase (NAD+) activity
HNV93_RS19140	COG5609	conserved protein (DUF2294)
HNV93_RS19145	COG2116	formate transmembrane transporter activity
HNV93_RS19160	COG2226	methyltransferase
HNV93_RS19165	COG1309	transcriptional regulator
HNV93_RS19170	COG2124	cytochrome p450
HNV93_RS19170	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HNV93_RS19175	COG2814	Major facilitator Superfamily
HNV93_RS19180	COG0583	DNA-binding transcription factor activity
HNV93_RS19185	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HNV93_RS19195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNV93_RS19195	COG3711	transcriptional antiterminator
HNV93_RS19200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNV93_RS19200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HNV93_RS19200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HNV93_RS19205	COG1482	cell wall glycoprotein biosynthetic process
HNV93_RS19215	COG0561	phosphatase activity
HNV93_RS19220	COG0561	phosphatase activity
HNV93_RS19230	COG2318	DinB family
HNV93_RS19235	COG0456	acetyltransferase
HNV93_RS19245	COG2814	Major facilitator Superfamily
HNV93_RS19250	COG0563	adenylate kinase activity
HNV93_RS19255	COG0454	-acetyltransferase
HNV93_RS19265	COG2311	Membrane
HNV93_RS19270	COG0745	RESPONSE REGULATOR receiver
HNV93_RS19275	COG5002	protein histidine kinase activity
HNV93_RS19275	COG0642	Histidine kinase
HNV93_RS19315	COG3677	Transposase