locus-tag	class	description
J4774_RS00005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4774_RS00005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4774_RS00005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS00005	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS00005	COG3321	synthase
J4774_RS00010	COG4221	oxidoreductase activity
J4774_RS00010	COG3321	synthase
J4774_RS00010	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS00010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS00015	COG3321	synthase
J4774_RS00015	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
J4774_RS00015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4774_RS00015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4774_RS00020	COG2124	cytochrome p450
J4774_RS00025	COG3209	COG3209 Rhs family protein
J4774_RS00030	COG3619	membrane
J4774_RS00040	COG1404	Belongs to the peptidase S8 family
J4774_RS00050	COG4195	phage-related replication protein
J4774_RS00055	COG1764	response to oxidative stress
J4774_RS00065	COG2076	Multidrug Resistance protein
J4774_RS00105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4774_RS00110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4774_RS00115	COG4112	unkown
J4774_RS00120	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4774_RS00125	COG0464	growth
J4774_RS00130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J4774_RS00135	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
J4774_RS00140	COG0789	Transcriptional regulator
J4774_RS00145	COG0174	glutamine synthetase
J4774_RS00155	COG2211	Major facilitator Superfamily
J4774_RS00160	COG3507	Belongs to the glycosyl hydrolase 43 family
J4774_RS00175	COG1070	Carbohydrate kinase
J4774_RS00180	COG3848	Pyruvate phosphate dikinase
J4774_RS00180	COG0574	Belongs to the PEP-utilizing enzyme family
J4774_RS00200	COG2378	regulation of single-species biofilm formation
J4774_RS00205	COG2318	DinB family
J4774_RS00210	COG1064	alcohol dehydrogenase
J4774_RS00230	COG0456	acetyltransferase
J4774_RS00250	COG3397	chitin binding
J4774_RS00270	COG5434	Belongs to the glycosyl hydrolase 28 family
J4774_RS00275	COG0756	dUTP diphosphatase activity
J4774_RS00280	COG4195	phage-related replication protein
J4774_RS00315	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J4774_RS00325	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4774_RS00345	COG0785	Cytochrome C biogenesis protein
J4774_RS00350	COG2201	protein-glutamate methylesterase activity
J4774_RS00355	COG4846	Membrane protein involved in cytochrome C biogenesis
J4774_RS00365	COG0071	Belongs to the small heat shock protein (HSP20) family
J4774_RS00380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J4774_RS00385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4774_RS00405	COG0824	Thioesterase
J4774_RS00415	COG4841	protein insertion into membrane
J4774_RS00425	COG1832	CoA-binding protein
J4774_RS00430	COG0187	DNA topoisomerase II activity
J4774_RS00435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J4774_RS00445	COG1115	amino acid carrier protein
J4774_RS00455	COG1063	alcohol dehydrogenase
J4774_RS00460	COG0800	Aldolase
J4774_RS00465	COG1312	Catalyzes the dehydration of D-mannonate
J4774_RS00470	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS00475	COG1609	Transcriptional regulator
J4774_RS00480	COG2271	Major facilitator Superfamily
J4774_RS00530	COG2205	protein histidine kinase activity
J4774_RS00535	COG0745	RESPONSE REGULATOR receiver
J4774_RS00545	COG3507	Belongs to the glycosyl hydrolase 43 family
J4774_RS00570	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS00575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J4774_RS00580	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J4774_RS00585	COG2610	gluconate transmembrane transporter activity
J4774_RS00590	COG2124	cytochrome p450
J4774_RS00610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4774_RS00620	COG2246	polysaccharide biosynthetic process
J4774_RS00625	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J4774_RS00630	COG0586	Pfam SNARE associated Golgi protein
J4774_RS00635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4774_RS00640	COG1024	Enoyl-CoA hydratase
J4774_RS00645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4774_RS00650	COG0511	ligase activity, forming carbon-carbon bonds
J4774_RS00655	COG0439	Biotin carboxylase
J4774_RS00660	COG0318	PFAM AMP-dependent synthetase and ligase
J4774_RS00665	COG1960	acyl-CoA dehydrogenase activity
J4774_RS00670	COG1649	PFAM Uncharacterised BCR, COG1649
J4774_RS00680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS00680	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
J4774_RS00685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS00690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS00695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS00700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS00705	COG2027	D-alanyl-D-alanine carboxypeptidase
J4774_RS00710	COG2017	converts alpha-aldose to the beta-anomer
J4774_RS00715	COG0534	Mate efflux family protein
J4774_RS00730	COG0582	viral genome integration into host DNA
J4774_RS00735	COG0166	Belongs to the GPI family
J4774_RS00740	COG0405	Gamma-glutamyltransferase
J4774_RS00745	COG2814	Major facilitator Superfamily
J4774_RS00750	COG0640	Transcriptional regulator
J4774_RS00765	COG0604	alcohol dehydrogenase
J4774_RS00770	COG0493	'glutamate synthase
J4774_RS00775	COG0067	glutamate synthase
J4774_RS00775	COG0069	glutamate synthase activity
J4774_RS00775	COG0070	glutamate synthase
J4774_RS00780	COG0583	DNA-binding transcription factor activity
J4774_RS00785	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J4774_RS00800	COG0300	oxidoreductase activity
J4774_RS00805	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
J4774_RS00815	COG2814	Major facilitator Superfamily
J4774_RS00820	COG1070	Carbohydrate kinase
J4774_RS00825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4774_RS00830	COG0243	molybdopterin cofactor binding
J4774_RS00850	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS00855	COG1733	regulation of RNA biosynthetic process
J4774_RS00860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4774_RS00865	COG0662	Cupin 2, conserved barrel domain protein
J4774_RS00865	COG2207	Transcriptional regulator
J4774_RS00870	COG1309	transcriptional regulator
J4774_RS00875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4774_RS00885	COG0640	Transcriptional regulator
J4774_RS00890	COG0741	lytic transglycosylase activity
J4774_RS00895	COG2322	membrane
J4774_RS00910	COG1619	proteins homologs of microcin C7 resistance protein MccF
J4774_RS00920	COG1388	LysM domain
J4774_RS00920	COG3584	3D domain protein
J4774_RS00925	COG0514	ATP-dependent DNA helicase (RecQ)
J4774_RS00935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J4774_RS00940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4774_RS00955	COG0071	Belongs to the small heat shock protein (HSP20) family
J4774_RS00985	COG1012	belongs to the aldehyde dehydrogenase family
J4774_RS00990	COG1657	PFAM Prenyltransferase squalene oxidase
J4774_RS00995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J4774_RS01000	COG0733	neurotransmitter:sodium symporter activity
J4774_RS01005	COG0385	Bile acid
J4774_RS01010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4774_RS01015	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4774_RS01025	COG4548	von Willebrand factor, type A
J4774_RS01030	COG0714	Associated with various cellular activities
J4774_RS01035	COG2032	superoxide dismutase activity
J4774_RS01040	COG0791	NLP P60 protein
J4774_RS01040	COG1388	LysM domain
J4774_RS01045	COG1819	glycosyl
J4774_RS01050	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J4774_RS01055	COG0534	Mate efflux family protein
J4774_RS01060	COG1366	Belongs to the anti-sigma-factor antagonist family
J4774_RS01065	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J4774_RS01070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J4774_RS01080	COG2962	Rard protein
J4774_RS01095	COG1942	4-Oxalocrotonate Tautomerase
J4774_RS01105	COG1733	regulation of RNA biosynthetic process
J4774_RS01110	COG0778	Nitroreductase
J4774_RS01115	COG0400	carboxylic ester hydrolase activity
J4774_RS01120	COG0346	lactoylglutathione lyase activity
J4774_RS01130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4774_RS01140	COG2723	6-phospho-beta-galactosidase activity
J4774_RS01145	COG2188	Transcriptional regulator
J4774_RS01150	COG0793	Belongs to the peptidase S41A family
J4774_RS01150	COG3409	Peptidoglycan-binding domain 1 protein
J4774_RS01155	COG2226	methyltransferase
J4774_RS01165	COG1876	peptidase activity
J4774_RS01185	COG0671	phosphoesterase, PA-phosphatase related
J4774_RS01220	COG1509	lysine 2,3-aminomutase activity
J4774_RS01225	COG0456	acetyltransferase
J4774_RS01230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4774_RS01235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J4774_RS01240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J4774_RS01245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4774_RS01260	COG0456	acetyltransferase
J4774_RS01265	COG0463	Glycosyl transferase, family 2
J4774_RS01280	COG4641	Protein conserved in bacteria
J4774_RS01290	COG1086	Polysaccharide biosynthesis protein
J4774_RS01330	COG1388	LysM domain
J4774_RS01335	COG0457	Tetratricopeptide repeat
J4774_RS01345	COG3391	amine dehydrogenase activity
J4774_RS01385	COG5444	nuclease activity
J4774_RS01390	COG4282	regulation of fungal-type cell wall biogenesis
J4774_RS01400	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J4774_RS01420	COG1846	Transcriptional regulator
J4774_RS01425	COG4698	Protein conserved in bacteria
J4774_RS01430	COG2755	lipolytic protein G-D-S-L family
J4774_RS01435	COG1999	signal sequence binding
J4774_RS01445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J4774_RS01450	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J4774_RS01455	COG1272	protein, Hemolysin III
J4774_RS01460	COG0204	Acyl-transferase
J4774_RS01465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J4774_RS01480	COG2136	Putative SAM-dependent methyltransferase
J4774_RS01480	COG2521	methyltransferase
J4774_RS01495	COG1413	lyase activity
J4774_RS01500	COG1418	mRNA catabolic process
J4774_RS01505	COG0386	Belongs to the glutathione peroxidase family
J4774_RS01515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J4774_RS01525	COG1278	Cold shock
J4774_RS01545	COG0328	RNA-DNA hybrid ribonuclease activity
J4774_RS01550	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J4774_RS01555	COG0328	RNA-DNA hybrid ribonuclease activity
J4774_RS01565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4774_RS01580	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J4774_RS01590	COG1755	Isoprenylcysteine carboxyl methyltransferase
J4774_RS01595	COG3424	synthase
J4774_RS01620	COG1335	isochorismatase
J4774_RS01630	COG2233	PERMEase
J4774_RS01640	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J4774_RS01645	COG1199	ATP-dependent helicase activity
J4774_RS01665	COG0116	Belongs to the methyltransferase superfamily
J4774_RS01695	COG3359	exonuclease
J4774_RS01700	COG1111	helicase
J4774_RS01700	COG1205	dead DEAH box helicase
J4774_RS01705	COG2190	(PTS) system
J4774_RS01710	COG0071	Belongs to the small heat shock protein (HSP20) family
J4774_RS01750	COG4499	WXG100 protein secretion system (Wss), protein YukC
J4774_RS01750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4774_RS01760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J4774_RS01765	COG3935	DnaD domain protein
J4774_RS01775	COG0436	Aminotransferase
J4774_RS01780	COG5353	protein conserved in bacteria
J4774_RS01790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J4774_RS01790	COG1199	ATP-dependent helicase activity
J4774_RS01820	COG0438	transferase activity, transferring glycosyl groups
J4774_RS01825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J4774_RS01840	COG1694	Mazg nucleotide pyrophosphohydrolase
J4774_RS01845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4774_RS01850	COG2140	Oxalate decarboxylase
J4774_RS01860	COG4347	Protein of unknown function (DUF1405)
J4774_RS01865	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J4774_RS01865	COG2010	Cytochrome c
J4774_RS01870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J4774_RS01875	COG0723	plastoquinol--plastocyanin reductase activity
J4774_RS01890	COG0457	Tetratricopeptide repeat
J4774_RS01900	COG0287	Prephenate dehydrogenase
J4774_RS01935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4774_RS01940	COG4401	Chorismate mutase type I
J4774_RS01955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4774_RS01960	COG0105	UTP biosynthetic process
J4774_RS01965	COG0142	geranyltranstransferase activity
J4774_RS01975	COG0142	geranyltranstransferase activity
J4774_RS01990	COG0776	regulation of translation
J4774_RS01995	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J4774_RS02035	COG0539	negative regulation of cytoplasmic translation
J4774_RS02050	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
J4774_RS02055	COG2959	enzyme of heme biosynthesis
J4774_RS02060	COG3773	Cell wall hydrolase
J4774_RS02060	COG3409	Peptidoglycan-binding domain 1 protein
J4774_RS02065	COG2339	peptidase activity
J4774_RS02070	COG0492	ferredoxin-NADP+ reductase activity
J4774_RS02075	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J4774_RS02080	COG4862	establishment of competence for transformation
J4774_RS02085	COG1408	metallophosphoesterase
J4774_RS02095	COG1388	LysM domain
J4774_RS02100	COG1266	CAAX protease self-immunity
J4774_RS02105	COG0514	ATP-dependent DNA helicase (RecQ)
J4774_RS02110	COG4955	Helix-turn-helix domain
J4774_RS02115	COG1141	Ferredoxin
J4774_RS02120	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
J4774_RS02125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4774_RS02135	COG1595	DNA-templated transcription, initiation
J4774_RS02140	COG5002	protein histidine kinase activity
J4774_RS02145	COG0745	RESPONSE REGULATOR receiver
J4774_RS02150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4774_RS02155	COG1333	cytochrome c biogenesis protein
J4774_RS02160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4774_RS02165	COG1187	pseudouridine synthase activity
J4774_RS02170	COG0700	Nucleoside recognition
J4774_RS02175	COG2715	membrane protein required for spore maturation
J4774_RS02180	COG1686	Belongs to the peptidase S11 family
J4774_RS02205	COG1547	Domain of unknown function (DUF309)
J4774_RS02210	COG0456	acetyltransferase
J4774_RS02225	COG0307	riboflavin synthase, alpha
J4774_RS02230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4774_RS02230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4774_RS02240	COG0681	Belongs to the peptidase S26 family
J4774_RS02250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4774_RS02255	COG4086	secreted protein
J4774_RS02260	COG0019	diaminopimelate decarboxylase activity
J4774_RS02265	COG0697	spore germination
J4774_RS02280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4774_RS02300	COG1191	sigma factor activity
J4774_RS02310	COG1366	Belongs to the anti-sigma-factor antagonist family
J4774_RS02315	COG1686	Belongs to the peptidase S11 family
J4774_RS02320	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J4774_RS02325	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J4774_RS02330	COG4974	Belongs to the 'phage' integrase family
J4774_RS02340	COG0735	belongs to the Fur family
J4774_RS02345	COG1300	Membrane
J4774_RS02360	COG0281	malic enzyme
J4774_RS02365	COG1757	Na H antiporter
J4774_RS02370	COG1027	Aspartate ammonia-lyase
J4774_RS02375	COG0252	asparaginase activity
J4774_RS02380	COG1396	sequence-specific DNA binding
J4774_RS02385	COG1379	DNA repair
J4774_RS02390	COG0494	nUDIX hydrolase
J4774_RS02400	COG0667	Aldo Keto reductase
J4774_RS02410	COG1073	alpha beta
J4774_RS02420	COG4918	Iron-sulphur cluster biosynthesis
J4774_RS02425	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J4774_RS02425	COG0456	acetyltransferase
J4774_RS02430	COG2329	Antibiotic biosynthesis monooxygenase
J4774_RS02435	COG0456	acetyltransferase
J4774_RS02440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4774_RS02455	COG0628	permease
J4774_RS02465	COG0346	lactoylglutathione lyase activity
J4774_RS02475	COG3048	D-serine ammonia-lyase activity
J4774_RS02480	COG0300	oxidoreductase activity
J4774_RS02485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4774_RS02490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4774_RS02495	COG1024	Enoyl-CoA hydratase
J4774_RS02500	COG3425	synthase
J4774_RS02505	COG2124	cytochrome p450
J4774_RS02510	COG3321	synthase
J4774_RS02510	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS02510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4774_RS02510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4774_RS02510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS02515	COG3321	synthase
J4774_RS02515	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS02515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS02515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4774_RS02515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4774_RS02520	COG0318	PFAM AMP-dependent synthetase and ligase
J4774_RS02520	COG3321	synthase
J4774_RS02520	COG0300	oxidoreductase activity
J4774_RS02520	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS02520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS02525	COG0300	oxidoreductase activity
J4774_RS02525	COG3321	synthase
J4774_RS02525	COG0318	PFAM AMP-dependent synthetase and ligase
J4774_RS02525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS02525	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS02530	COG3321	synthase
J4774_RS02530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS02530	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS02530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4774_RS02530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4774_RS02535	COG0318	PFAM AMP-dependent synthetase and ligase
J4774_RS02535	COG3321	synthase
J4774_RS02535	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS02535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS02535	COG0300	oxidoreductase activity
J4774_RS02540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4774_RS02540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4774_RS02540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS02540	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS02540	COG3321	synthase
J4774_RS02545	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS02550	COG0318	PFAM AMP-dependent synthetase and ligase
J4774_RS02565	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J4774_RS02565	COG2070	2-Nitropropane dioxygenase
J4774_RS02570	COG0250	Participates in transcription elongation, termination and antitermination
J4774_RS02590	COG0596	Alpha beta hydrolase
J4774_RS02605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J4774_RS02610	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4774_RS02625	COG0706	membrane insertase activity
J4774_RS02630	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4774_RS02635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4774_RS02640	COG0346	lactoylglutathione lyase activity
J4774_RS02650	COG1376	ErfK ybiS ycfS ynhG family protein
J4774_RS02655	COG4129	membrane
J4774_RS02660	COG1126	abc transporter atp-binding protein
J4774_RS02665	COG0765	amino acid transport
J4774_RS02670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4774_RS02680	COG1597	lipid kinase activity
J4774_RS02685	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4774_RS02690	COG0022	dehydrogenase e1 component
J4774_RS02695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J4774_RS02700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4774_RS02705	COG3426	butyrate kinase activity
J4774_RS02710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J4774_RS02715	COG0280	phosphate acetyltransferase
J4774_RS02720	COG3290	protein histidine kinase activity
J4774_RS02720	COG3829	transcription factor binding
J4774_RS02730	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J4774_RS02735	COG2079	MmgE PrpD family protein
J4774_RS02740	COG0372	Belongs to the citrate synthase family
J4774_RS02745	COG1960	acyl-CoA dehydrogenase activity
J4774_RS02750	COG1250	3-hydroxyacyl-CoA dehydrogenase
J4774_RS02755	COG0183	Belongs to the thiolase family
J4774_RS02760	COG0584	glycerophosphoryl diester phosphodiesterase
J4774_RS02765	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4774_RS02790	COG1902	pentaerythritol trinitrate reductase activity
J4774_RS02805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4774_RS02810	COG0745	RESPONSE REGULATOR receiver
J4774_RS02815	COG0750	zinc metalloprotease
J4774_RS02820	COG0497	DNA recombination
J4774_RS02830	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J4774_RS02840	COG0142	geranyltranstransferase activity
J4774_RS02850	COG1570	exodeoxyribonuclease VII activity
J4774_RS02865	COG1302	Protein conserved in bacteria
J4774_RS02870	COG0439	Biotin carboxylase
J4774_RS02875	COG0511	ligase activity, forming carbon-carbon bonds
J4774_RS02915	COG3854	ATPases associated with a variety of cellular activities
J4774_RS02930	COG0006	proline dipeptidase activity
J4774_RS02940	COG3872	metal-dependent enzyme
J4774_RS02950	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4774_RS02965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4774_RS02985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J4774_RS03000	COG1396	sequence-specific DNA binding
J4774_RS03010	COG0681	Belongs to the peptidase S26 family
J4774_RS03035	COG4940	Competence protein ComGF
J4774_RS03045	COG4970	Tfp pilus assembly protein FimT
J4774_RS03050	COG4537	Required for transformation and DNA binding
J4774_RS03055	COG1459	type II secretion system
J4774_RS03060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4774_RS03065	COG0598	Magnesium transport protein CorA
J4774_RS03070	COG1253	flavin adenine dinucleotide binding
J4774_RS03075	COG1366	Belongs to the anti-sigma-factor antagonist family
J4774_RS03085	COG1393	Belongs to the ArsC family
J4774_RS03095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4774_RS03105	COG0011	TIGRFAM Protein of
J4774_RS03115	COG2866	Carboxypeptidase
J4774_RS03120	COG1940	carbohydrate kinase activity
J4774_RS03125	COG4483	Protein conserved in bacteria
J4774_RS03130	COG1757	Na H antiporter
J4774_RS03140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J4774_RS03155	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4774_RS03160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4774_RS03165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4774_RS03170	COG0581	inorganic phosphate transmembrane transporter activity
J4774_RS03175	COG0573	inorganic phosphate transmembrane transporter activity
J4774_RS03180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J4774_RS03185	COG0768	penicillin binding
J4774_RS03190	COG0477	Major facilitator Superfamily
J4774_RS03195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J4774_RS03200	COG2839	Protein conserved in bacteria
J4774_RS03205	COG5521	maltodextrose utilization protein MalA
J4774_RS03210	COG1388	LysM domain
J4774_RS03220	COG4709	membrane
J4774_RS03225	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
J4774_RS03230	COG0735	belongs to the Fur family
J4774_RS03235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4774_RS03250	COG0513	Belongs to the DEAD box helicase family
J4774_RS03265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J4774_RS03270	COG2384	SAM-dependent methyltransferase
J4774_RS03275	COG2010	Cytochrome c
J4774_RS03280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4774_RS03285	COG0358	DNA primase activity
J4774_RS03300	COG0517	IMP dehydrogenase activity
J4774_RS03305	COG0751	glycine-tRNA ligase activity
J4774_RS03325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J4774_RS03330	COG0295	cytidine deaminase activity
J4774_RS03335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4774_RS03345	COG1480	7TM receptor with intracellular HD hydrolase
J4774_RS03350	COG1702	phosphate starvation-inducible protein PhoH
J4774_RS03355	COG0561	phosphatase activity
J4774_RS03370	COG4864	UPF0365 protein
J4774_RS03375	COG1030	water channel activity
J4774_RS03380	COG1610	YqeY-like protein
J4774_RS03390	COG1283	sodium-dependent phosphate transmembrane transporter activity
J4774_RS03395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J4774_RS03400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J4774_RS03430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4774_RS03445	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4774_RS03460	COG1466	dna polymerase III delta subunit
J4774_RS03475	COG0658	competence protein
J4774_RS03475	COG2333	competence protein COMEC
J4774_RS03480	COG2131	deaminase
J4774_RS03485	COG1596	polysaccharide export
J4774_RS03485	COG1555	photosystem II stabilization
J4774_RS03490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4774_RS03495	COG2226	methyltransferase
J4774_RS03500	COG0799	negative regulation of ribosome biogenesis
J4774_RS03505	COG1713	HD superfamily hydrolase involved in NAD metabolism
J4774_RS03515	COG1534	Rna-binding protein
J4774_RS03520	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J4774_RS03525	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4774_RS03530	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
J4774_RS03540	COG2755	lipolytic protein G-D-S-L family
J4774_RS03550	COG0398	Pfam SNARE associated Golgi protein
J4774_RS03575	COG2207	Transcriptional regulator
J4774_RS03575	COG3708	Transcriptional regulator
J4774_RS03580	COG0563	adenylate kinase activity
J4774_RS03585	COG2814	Major facilitator Superfamily
J4774_RS03605	COG5444	nuclease activity
J4774_RS03645	COG0456	acetyltransferase
J4774_RS03650	COG2318	DinB family
J4774_RS03660	COG0561	phosphatase activity
J4774_RS03665	COG0561	phosphatase activity
J4774_RS03675	COG1482	cell wall glycoprotein biosynthetic process
J4774_RS03680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4774_RS03680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4774_RS03680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4774_RS03685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4774_RS03685	COG3711	transcriptional antiterminator
J4774_RS03695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J4774_RS03700	COG0583	DNA-binding transcription factor activity
J4774_RS03705	COG2814	Major facilitator Superfamily
J4774_RS03710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4774_RS03710	COG2124	cytochrome p450
J4774_RS03715	COG1309	transcriptional regulator
J4774_RS03720	COG2226	methyltransferase
J4774_RS03735	COG2116	formate transmembrane transporter activity
J4774_RS03740	COG5609	conserved protein (DUF2294)
J4774_RS03745	COG3383	formate dehydrogenase (NAD+) activity
J4774_RS03750	COG2427	Protein of unknown function (DUF1641)
J4774_RS03760	COG0626	cystathionine gamma-synthase activity
J4774_RS03765	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4774_RS03790	COG0768	penicillin binding
J4774_RS03805	COG0826	peptidase U32
J4774_RS03810	COG0826	peptidase U32
J4774_RS03815	COG4122	O-methyltransferase activity
J4774_RS03820	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4774_RS03835	COG4472	Bacterial protein of unknown function (DUF965)
J4774_RS03845	COG0628	permease
J4774_RS03850	COG1126	abc transporter atp-binding protein
J4774_RS03855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4774_RS03860	COG0765	amino acid transport
J4774_RS03865	COG0765	amino acid transport
J4774_RS03880	COG3881	PFAM PRC-barrel domain
J4774_RS03885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4774_RS03890	COG0457	Tetratricopeptide repeat
J4774_RS03900	COG1104	cysteine desulfurase activity
J4774_RS03905	COG1959	2 iron, 2 sulfur cluster binding
J4774_RS03910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J4774_RS03915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J4774_RS03940	COG4991	sh3 domain protein
J4774_RS03940	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4774_RS03940	COG3103	Sh3 type 3 domain protein
J4774_RS03950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4774_RS03960	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
J4774_RS03960	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J4774_RS03965	COG5416	Lipopolysaccharide assembly protein A domain
J4774_RS03970	COG0490	domain, Protein
J4774_RS03975	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4774_RS03975	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4774_RS03985	COG2244	polysaccharide biosynthetic process
J4774_RS03990	COG2323	membrane
J4774_RS04000	COG1862	Preprotein translocase
J4774_RS04045	COG1388	LysM domain
J4774_RS04055	COG0157	Belongs to the NadC ModD family
J4774_RS04060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J4774_RS04065	COG1104	cysteine desulfurase activity
J4774_RS04070	COG1827	regulation of RNA biosynthetic process
J4774_RS04075	COG0077	Prephenate dehydratase
J4774_RS04090	COG3290	protein histidine kinase activity
J4774_RS04095	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J4774_RS04100	COG2868	ribosomal protein
J4774_RS04110	COG1994	Peptidase M50
J4774_RS04115	COG0739	heme binding
J4774_RS04120	COG2894	cell division
J4774_RS04130	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J4774_RS04140	COG1077	Cell shape determining protein MreB Mrl
J4774_RS04160	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J4774_RS04165	COG0285	dihydrofolate synthase activity
J4774_RS04170	COG0525	valine-tRNA ligase activity
J4774_RS04180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4774_RS04185	COG1388	LysM domain
J4774_RS04195	COG0113	porphobilinogen synthase activity
J4774_RS04200	COG1587	Uroporphyrinogen-III synthase
J4774_RS04210	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4774_RS04230	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J4774_RS04235	COG0470	DNA polymerase III
J4774_RS04235	COG1067	ATP-dependent peptidase activity
J4774_RS04250	COG0457	Tetratricopeptide repeat
J4774_RS04250	COG1477	protein flavinylation
J4774_RS04265	COG0473	3-isopropylmalate dehydrogenase activity
J4774_RS04280	COG0440	acetolactate synthase activity
J4774_RS04285	COG0028	Belongs to the TPP enzyme family
J4774_RS04310	COG0622	Phosphoesterase
J4774_RS04315	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J4774_RS04325	COG5401	PFAM Sporulation and spore germination
J4774_RS04335	COG1846	Transcriptional regulator
J4774_RS04340	COG2197	response regulator
J4774_RS04345	COG0824	Thioesterase
J4774_RS04350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4774_RS04355	COG1053	succinate dehydrogenase
J4774_RS04360	COG2009	succinate dehydrogenase
J4774_RS04365	COG1719	4-vinyl reductase, 4VR
J4774_RS04370	COG0527	aspartate kinase activity
J4774_RS04380	COG3118	belongs to the thioredoxin family
J4774_RS04385	COG3534	alpha-L-arabinofuranosidase
J4774_RS04390	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
J4774_RS04395	COG2086	electron transfer activity
J4774_RS04400	COG1024	Enoyl-CoA hydratase
J4774_RS04405	COG1309	transcriptional regulator
J4774_RS04410	COG0318	PFAM AMP-dependent synthetase and ligase
J4774_RS04420	COG3766	membrane
J4774_RS04430	COG1796	DNA polymerase
J4774_RS04430	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4774_RS04435	COG1286	toxin biosynthetic process
J4774_RS04450	COG0072	phenylalanine-tRNA ligase activity
J4774_RS04450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4774_RS04455	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J4774_RS04460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4774_RS04470	COG3835	regulator
J4774_RS04475	COG0277	FAD linked oxidase domain protein
J4774_RS04480	COG0247	lactate metabolic process
J4774_RS04485	COG1966	Carbon starvation protein
J4774_RS04490	COG3534	alpha-L-arabinofuranosidase
J4774_RS04495	COG0395	ABC-type sugar transport system, permease component
J4774_RS04500	COG1175	transmembrane transport
J4774_RS04505	COG1653	transport
J4774_RS04515	COG0647	UMP catabolic process
J4774_RS04520	COG0235	Class ii aldolase
J4774_RS04525	COG1069	ribulokinase activity
J4774_RS04530	COG2160	L-arabinose isomerase activity
J4774_RS04535	COG3507	Belongs to the glycosyl hydrolase 43 family
J4774_RS04540	COG1363	Peptidase, m42
J4774_RS04550	COG3326	Membrane
J4774_RS04555	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J4774_RS04565	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J4774_RS04570	COG1346	cytolysis
J4774_RS04575	COG1380	Effector of murein hydrolase LrgA
J4774_RS04580	COG3279	Response regulator of the LytR AlgR family
J4774_RS04585	COG3275	phosphorelay sensor kinase activity
J4774_RS04590	COG1011	Hydrolase
J4774_RS04605	COG0398	Pfam SNARE associated Golgi protein
J4774_RS04610	COG1484	DNA-dependent DNA replication
J4774_RS04615	COG3611	Membrane attachment protein
J4774_RS04630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4774_RS04635	COG1733	regulation of RNA biosynthetic process
J4774_RS04640	COG2814	Major facilitator Superfamily
J4774_RS04645	COG0656	L-ascorbic acid biosynthetic process
J4774_RS04650	COG0237	dephospho-CoA kinase activity
J4774_RS04655	COG1971	Probably functions as a manganese efflux pump
J4774_RS04660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J4774_RS04665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4774_RS04665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4774_RS04670	COG5002	protein histidine kinase activity
J4774_RS04675	COG0745	RESPONSE REGULATOR receiver
J4774_RS04685	COG0538	isocitrate dehydrogenase activity
J4774_RS04690	COG0372	Belongs to the citrate synthase family
J4774_RS04715	COG0628	permease
J4774_RS04720	COG3030	protein affecting phage T7 exclusion by the F plasmid
J4774_RS04725	COG0469	pyruvate kinase activity
J4774_RS04745	COG0281	malic enzyme
J4774_RS04750	COG0587	DNA-directed DNA polymerase activity
J4774_RS04770	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J4774_RS04780	COG4109	DRTGG domain
J4774_RS04790	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS04805	COG0521	Mo-molybdopterin cofactor biosynthetic process
J4774_RS04815	COG0827	DNA restriction-modification system
J4774_RS04820	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J4774_RS04825	COG3874	Sporulation protein YtfJ
J4774_RS04835	COG1714	RDD family
J4774_RS04840	COG0616	signal peptide processing
J4774_RS04845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J4774_RS04850	COG1574	metal-dependent hydrolase with the TIM-barrel fold
J4774_RS04855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4774_RS04870	COG1104	cysteine desulfurase activity
J4774_RS04875	COG1114	Component of the transport system for branched-chain amino acids
J4774_RS04885	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4774_RS04890	COG1309	transcriptional regulator
J4774_RS04895	COG1956	GAF domain-containing protein
J4774_RS04900	COG2199	diguanylate cyclase activity
J4774_RS04900	COG2203	Gaf domain
J4774_RS04910	COG1012	belongs to the aldehyde dehydrogenase family
J4774_RS04935	COG1017	nitric oxide dioxygenase activity
J4774_RS04935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4774_RS04945	COG0693	protein deglycase activity
J4774_RS04960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4774_RS04965	COG1378	Sugar-specific transcriptional regulator TrmB
J4774_RS04985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4774_RS04990	COG0454	-acetyltransferase
J4774_RS04995	COG0517	IMP dehydrogenase activity
J4774_RS05000	COG0123	including yeast histone deacetylase and acetoin utilization protein
J4774_RS05005	COG1360	Flagellar Motor Protein
J4774_RS05010	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4774_RS05015	COG1609	Transcriptional regulator
J4774_RS05020	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
J4774_RS05020	COG1605	Chorismate mutase
J4774_RS05025	COG3118	belongs to the thioredoxin family
J4774_RS05030	COG4980	gas vesicle protein
J4774_RS05035	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
J4774_RS05045	COG1674	ftsk spoiiie
J4774_RS05050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4774_RS05060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4774_RS05070	COG1363	Peptidase, m42
J4774_RS05075	COG5584	Small secreted protein
J4774_RS05080	COG0281	malic enzyme
J4774_RS05085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4774_RS05100	COG0510	thiamine kinase activity
J4774_RS05105	COG1597	lipid kinase activity
J4774_RS05115	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
J4774_RS05120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4774_RS05125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4774_RS05130	COG2252	PERMEase
J4774_RS05135	COG4473	ABC transporter
J4774_RS05140	COG1131	(ABC) transporter
J4774_RS05145	COG1349	DNA-binding transcription factor activity
J4774_RS05150	COG1187	pseudouridine synthase activity
J4774_RS05155	COG2244	polysaccharide biosynthetic process
J4774_RS05160	COG2081	HI0933 family
J4774_RS05165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4774_RS05175	COG1609	Transcriptional regulator
J4774_RS05180	COG1653	transport
J4774_RS05185	COG1175	transmembrane transport
J4774_RS05190	COG0395	ABC-type sugar transport system, permease component
J4774_RS05195	COG1486	melibiose metabolic process
J4774_RS05205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4774_RS05220	COG1366	Belongs to the anti-sigma-factor antagonist family
J4774_RS05220	COG2202	Pas domain
J4774_RS05225	COG2814	Major facilitator Superfamily
J4774_RS05230	COG5522	Integral membrane protein (intg_mem_TP0381)
J4774_RS05235	COG0577	efflux transmembrane transporter activity
J4774_RS05240	COG1136	(ABC) transporter
J4774_RS05245	COG2205	protein histidine kinase activity
J4774_RS05250	COG0745	RESPONSE REGULATOR receiver
J4774_RS05255	COG0577	efflux transmembrane transporter activity
J4774_RS05260	COG1136	(ABC) transporter
J4774_RS05280	COG1131	(ABC) transporter
J4774_RS05285	COG1725	Transcriptional regulator
J4774_RS05295	COG1242	4 iron, 4 sulfur cluster binding
J4774_RS05300	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J4774_RS05310	COG0584	glycerophosphoryl diester phosphodiesterase
J4774_RS05320	COG2267	carboxylic ester hydrolase activity
J4774_RS05325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J4774_RS05330	COG1113	amino acid transport
J4774_RS05335	COG0367	asparagine synthase
J4774_RS05355	COG1506	peptidase
J4774_RS05360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4774_RS05365	COG1116	anion transmembrane transporter activity
J4774_RS05370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4774_RS05375	COG0494	nUDIX hydrolase
J4774_RS05380	COG4824	toxin secretion phage lysis holin
J4774_RS05385	COG0783	Belongs to the Dps family
J4774_RS05410	COG0288	reversible hydration of carbon dioxide
J4774_RS05420	COG1271	oxidase subunit
J4774_RS05425	COG1294	oxidase, subunit
J4774_RS05435	COG4948	Mandelate Racemase Muconate Lactonizing
J4774_RS05445	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J4774_RS05450	COG0596	Alpha beta hydrolase
J4774_RS05460	COG1169	isochorismate synthase
J4774_RS05465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4774_RS05470	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
J4774_RS05595	COG3859	Proton-coupled thiamine transporter YuaJ
J4774_RS05600	COG2268	Band 7 protein
J4774_RS05605	COG1585	Membrane protein implicated in regulation of membrane protease activity
J4774_RS05610	COG2318	DinB family
J4774_RS05620	COG1454	alcohol dehydrogenase
J4774_RS05625	COG1012	belongs to the aldehyde dehydrogenase family
J4774_RS05630	COG1510	regulation of RNA biosynthetic process
J4774_RS05640	COG0569	domain protein
J4774_RS05645	COG1705	Flagellar rod assembly protein muramidase FlgJ
J4774_RS05650	COG1017	nitric oxide dioxygenase activity
J4774_RS05650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4774_RS05665	COG0457	Tetratricopeptide repeat
J4774_RS05690	COG0628	permease
J4774_RS05695	COG0673	inositol 2-dehydrogenase activity
J4774_RS05700	COG0693	protein deglycase activity
J4774_RS05705	COG0840	transmembrane signaling receptor activity
J4774_RS05710	COG0840	transmembrane signaling receptor activity
J4774_RS05715	COG0840	transmembrane signaling receptor activity
J4774_RS05720	COG0840	transmembrane signaling receptor activity
J4774_RS05735	COG2070	2-Nitropropane dioxygenase
J4774_RS05740	COG0432	Pfam Uncharacterised protein family UPF0047
J4774_RS05745	COG0366	Alpha amylase catalytic
J4774_RS05750	COG1253	flavin adenine dinucleotide binding
J4774_RS05755	COG2738	Putative neutral zinc metallopeptidase
J4774_RS05770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4774_RS05795	COG1335	isochorismatase
J4774_RS05800	COG1979	alcohol dehydrogenase
J4774_RS05805	COG1979	alcohol dehydrogenase
J4774_RS05810	COG2155	Conserved Protein
J4774_RS05815	COG1098	S1 RNA binding domain
J4774_RS05820	COG0436	Aminotransferase
J4774_RS05825	COG1522	sequence-specific DNA binding
J4774_RS05830	COG2267	carboxylic ester hydrolase activity
J4774_RS05840	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J4774_RS05845	COG2205	protein histidine kinase activity
J4774_RS05855	COG5018	Exonuclease
J4774_RS05860	COG2814	Major facilitator Superfamily
J4774_RS05865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4774_RS05870	COG3011	Protein conserved in bacteria
J4774_RS05880	COG3290	protein histidine kinase activity
J4774_RS05885	COG4565	transcriptional regulatory protein
J4774_RS05890	COG1744	ABC transporter substrate-binding protein PnrA-like
J4774_RS05895	COG3845	ABC transporter
J4774_RS05900	COG4603	Belongs to the binding-protein-dependent transport system permease family
J4774_RS05905	COG1079	Belongs to the binding-protein-dependent transport system permease family
J4774_RS05915	COG2111	Na H antiporter
J4774_RS05915	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J4774_RS05920	COG2111	Na H antiporter
J4774_RS05925	COG1006	Multisubunit Na H antiporter MnhC subunit
J4774_RS05930	COG0651	ATP synthesis coupled electron transport
J4774_RS05935	COG1863	multisubunit Na H antiporter MnhE subunit
J4774_RS05940	COG2212	antiporter activity
J4774_RS05945	COG1320	monovalent cation:proton antiporter activity
J4774_RS05950	COG2050	protein possibly involved in aromatic compounds catabolism
J4774_RS05955	COG2197	response regulator
J4774_RS05960	COG4585	Histidine kinase
J4774_RS05970	COG0142	geranyltranstransferase activity
J4774_RS05985	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4774_RS05990	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J4774_RS05995	COG1335	isochorismatase
J4774_RS06000	COG5506	Protein of unknown function (DUF1694)
J4774_RS06015	COG0628	permease
J4774_RS06025	COG1418	mRNA catabolic process
J4774_RS06030	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS06040	COG1511	domain protein
J4774_RS06045	COG1674	ftsk spoiiie
J4774_RS06045	COG0433	COG0433 Predicted ATPase
J4774_RS06050	COG4499	WXG100 protein secretion system (Wss), protein YukC
J4774_RS06055	COG5417	Belongs to the EsaB family
J4774_RS06060	COG4842	Belongs to the WXG100 family
J4774_RS06065	COG2508	Transcriptional regulator
J4774_RS06065	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
J4774_RS06070	COG0686	Belongs to the AlaDH PNT family
J4774_RS06075	COG5634	Uncharacterized conserved protein (DUF2278)
J4774_RS06080	COG3251	PFAM MbtH domain protein
J4774_RS06085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS06090	COG1535	isochorismatase
J4774_RS06090	COG3433	isochorismatase activity
J4774_RS06095	COG1021	2,3-dihydroxybenzoate-AMP ligase
J4774_RS06100	COG1169	isochorismate synthase
J4774_RS06105	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS06110	COG2819	hydrolase of the alpha beta superfamily
J4774_RS06115	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J4774_RS06120	COG1268	BioY protein
J4774_RS06125	COG2056	Na+-H+ antiporter family
J4774_RS06135	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
J4774_RS06140	COG3584	3D domain protein
J4774_RS06155	COG1252	NADH dehydrogenase
J4774_RS06185	COG1131	(ABC) transporter
J4774_RS06210	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
J4774_RS06215	COG0316	Belongs to the HesB IscA family
J4774_RS06225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4774_RS06235	COG1252	NADH dehydrogenase
J4774_RS06240	COG4837	Protein of unknown function (DUF1462)
J4774_RS06245	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J4774_RS06250	COG0823	Involved in the tonB-independent uptake of proteins
J4774_RS06250	COG1506	peptidase
J4774_RS06250	COG4946	Tricorn protease homolog
J4774_RS06260	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J4774_RS06265	COG0460	homoserine dehydrogenase
J4774_RS06270	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4774_RS06275	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J4774_RS06280	COG0647	UMP catabolic process
J4774_RS06285	COG2445	Protein of unknown function DUF86
J4774_RS06290	COG4470	Protein conserved in bacteria
J4774_RS06300	COG0739	heme binding
J4774_RS06310	COG0737	Belongs to the 5'-nucleotidase family
J4774_RS06315	COG0730	response to heat
J4774_RS06320	COG1801	Protein of unknown function DUF72
J4774_RS06335	COG2508	Transcriptional regulator
J4774_RS06345	COG2814	Major facilitator Superfamily
J4774_RS06350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4774_RS06355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4774_RS06360	COG2356	endonuclease I
J4774_RS06365	COG3842	ATPase activity
J4774_RS06370	COG2188	Transcriptional regulator
J4774_RS06375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4774_RS06380	COG0395	ABC-type sugar transport system, permease component
J4774_RS06385	COG1175	transmembrane transport
J4774_RS06390	COG1653	transport
J4774_RS06395	COG2222	sugar isomerase
J4774_RS06400	COG0789	Transcriptional regulator
J4774_RS06415	COG0322	excinuclease ABC activity
J4774_RS06420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4774_RS06430	COG3409	Peptidoglycan-binding domain 1 protein
J4774_RS06435	COG0719	Fe-S assembly protein
J4774_RS06440	COG0822	iron-sulfur transferase activity
J4774_RS06445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4774_RS06450	COG0719	Fe-S assembly protein
J4774_RS06455	COG0396	ATPase activity
J4774_RS06465	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4774_RS06470	COG1464	Belongs to the NlpA lipoprotein family
J4774_RS06475	COG2011	ABC-type metal ion transport system permease component
J4774_RS06480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4774_RS06490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4774_RS06495	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J4774_RS06510	COG1393	Belongs to the ArsC family
J4774_RS06515	COG1960	acyl-CoA dehydrogenase activity
J4774_RS06520	COG0183	Belongs to the thiolase family
J4774_RS06525	COG1024	Enoyl-CoA hydratase
J4774_RS06525	COG1250	3-hydroxyacyl-CoA dehydrogenase
J4774_RS06545	COG5577	PFAM Coat F domain
J4774_RS06550	COG1846	Transcriptional regulator
J4774_RS06555	COG0477	Major facilitator Superfamily
J4774_RS06560	COG0583	DNA-binding transcription factor activity
J4774_RS06580	COG1120	ATPase activity
J4774_RS06595	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS06600	COG0783	Belongs to the Dps family
J4774_RS06605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4774_RS06610	COG0745	RESPONSE REGULATOR receiver
J4774_RS06615	COG2205	protein histidine kinase activity
J4774_RS06615	COG2770	Histidine kinase
J4774_RS06625	COG1309	transcriptional regulator
J4774_RS06630	COG0114	fumarate hydratase activity
J4774_RS06640	COG0697	spore germination
J4774_RS06645	COG0814	amino acid
J4774_RS06655	COG2197	response regulator
J4774_RS06660	COG4585	Histidine kinase
J4774_RS06665	COG4758	membrane
J4774_RS06670	COG3595	metallopeptidase activity
J4774_RS06675	COG1842	Phage shock protein A
J4774_RS06680	COG4758	membrane
J4774_RS06685	COG2814	Major facilitator Superfamily
J4774_RS06690	COG2096	Adenosyltransferase
J4774_RS06695	COG1120	ATPase activity
J4774_RS06700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4774_RS06705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4774_RS06710	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS06715	COG3386	PFAM SMP-30 Gluconolaconase
J4774_RS06720	COG2205	protein histidine kinase activity
J4774_RS06725	COG0745	RESPONSE REGULATOR receiver
J4774_RS06735	COG1191	sigma factor activity
J4774_RS06745	COG2140	Oxalate decarboxylase
J4774_RS06755	COG1120	ATPase activity
J4774_RS06760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4774_RS06765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4774_RS06770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4774_RS06775	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
J4774_RS06780	COG0531	amino acid
J4774_RS06790	COG1988	membrane-bound metal-dependent
J4774_RS06795	COG1368	sulfuric ester hydrolase activity
J4774_RS06800	COG1910	domain protein
J4774_RS06805	COG0725	ABC transporter, periplasmic molybdate-binding protein
J4774_RS06810	COG4149	molybdate abc transporter
J4774_RS06815	COG2197	response regulator
J4774_RS06820	COG3850	Histidine kinase
J4774_RS06825	COG1131	(ABC) transporter
J4774_RS06835	COG0842	Transport permease protein
J4774_RS06840	COG0656	L-ascorbic acid biosynthetic process
J4774_RS06860	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4774_RS06865	COG3973	AAA domain
J4774_RS06870	COG2860	membrane
J4774_RS06880	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J4774_RS06885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4774_RS06890	COG2217	Heavy metal translocating P-type atpase
J4774_RS06895	COG2217	Heavy metal translocating P-type atpase
J4774_RS06900	COG2608	mercury ion transmembrane transporter activity
J4774_RS06905	COG1937	Protein conserved in bacteria
J4774_RS06910	COG0673	inositol 2-dehydrogenase activity
J4774_RS06925	COG2814	Major facilitator Superfamily
J4774_RS06940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4774_RS06945	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4774_RS06950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4774_RS06955	COG1126	abc transporter atp-binding protein
J4774_RS06960	COG0765	amino acid transport
J4774_RS06965	COG0765	amino acid transport
J4774_RS06970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4774_RS06975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4774_RS06980	COG0454	-acetyltransferase
J4774_RS06985	COG0583	DNA-binding transcription factor activity
J4774_RS06990	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS06995	COG2732	(Barnase) inhibitor
J4774_RS07015	COG0557	exoribonuclease II activity
J4774_RS07020	COG1647	Serine aminopeptidase, S33
J4774_RS07025	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4774_RS07030	COG1476	TRANSCRIPTIONal
J4774_RS07035	COG1396	sequence-specific DNA binding
J4774_RS07040	COG1396	sequence-specific DNA binding
J4774_RS07045	COG1733	regulation of RNA biosynthetic process
J4774_RS07070	COG1131	(ABC) transporter
J4774_RS07075	COG1174	glycine betaine transport
J4774_RS07080	COG1732	Glycine betaine
J4774_RS07085	COG1174	glycine betaine transport
J4774_RS07090	COG0517	IMP dehydrogenase activity
J4774_RS07090	COG1125	glycine betaine transport
J4774_RS07095	COG1510	regulation of RNA biosynthetic process
J4774_RS07100	COG1174	glycine betaine transport
J4774_RS07105	COG1732	Glycine betaine
J4774_RS07110	COG1174	glycine betaine transport
J4774_RS07115	COG1125	glycine betaine transport
J4774_RS07115	COG0517	IMP dehydrogenase activity
J4774_RS07120	COG1510	regulation of RNA biosynthetic process
J4774_RS07125	COG2095	MarC family integral membrane protein
J4774_RS07130	COG3064	Membrane
J4774_RS07135	COG4640	response to antibiotic
J4774_RS07140	COG0456	acetyltransferase
J4774_RS07155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J4774_RS07170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4774_RS07175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4774_RS07180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4774_RS07190	COG2234	aminopeptidase activity
J4774_RS07210	COG0126	phosphoglycerate kinase activity
J4774_RS07215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4774_RS07220	COG2390	Transcriptional regulator
J4774_RS07225	COG2814	Major facilitator Superfamily
J4774_RS07230	COG1609	Transcriptional regulator
J4774_RS07235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4774_RS07245	COG0583	DNA-binding transcription factor activity
J4774_RS07250	COG0697	spore germination
J4774_RS07255	COG1113	amino acid transport
J4774_RS07260	COG1737	Transcriptional regulator
J4774_RS07265	COG1070	Carbohydrate kinase
J4774_RS07290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4774_RS07295	COG2186	Transcriptional regulator
J4774_RS07300	COG1620	l-lactate permease
J4774_RS07305	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J4774_RS07315	COG5039	Polysaccharide pyruvyl transferase
J4774_RS07320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4774_RS07325	COG0110	maltose O-acetyltransferase activity
J4774_RS07330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4774_RS07335	COG2244	polysaccharide biosynthetic process
J4774_RS07340	COG1216	Glycosyl transferase, family 2
J4774_RS07345	COG5039	Polysaccharide pyruvyl transferase
J4774_RS07350	COG1216	Glycosyl transferase, family 2
J4774_RS07360	COG0438	transferase activity, transferring glycosyl groups
J4774_RS07365	COG1215	transferase activity, transferring glycosyl groups
J4774_RS07370	COG0438	transferase activity, transferring glycosyl groups
J4774_RS07375	COG1086	Polysaccharide biosynthesis protein
J4774_RS07380	COG0489	protein tyrosine kinase activity
J4774_RS07385	COG3944	biosynthesis protein
J4774_RS07390	COG1396	sequence-specific DNA binding
J4774_RS07395	COG2272	Belongs to the type-B carboxylesterase lipase family
J4774_RS07405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J4774_RS07410	COG2364	Membrane
J4774_RS07415	COG0456	acetyltransferase
J4774_RS07420	COG3479	Phenolic acid decarboxylase
J4774_RS07480	COG2223	nitrite transmembrane transporter activity
J4774_RS07485	COG1609	Transcriptional regulator
J4774_RS07495	COG0583	DNA-binding transcription factor activity
J4774_RS07500	COG2828	Protein conserved in bacteria
J4774_RS07505	COG2814	Major facilitator Superfamily
J4774_RS07505	COG0477	Major facilitator Superfamily
J4774_RS07510	COG1611	Belongs to the LOG family
J4774_RS07515	COG1694	Mazg nucleotide pyrophosphohydrolase
J4774_RS07520	COG0659	secondary active sulfate transmembrane transporter activity
J4774_RS07525	COG0288	reversible hydration of carbon dioxide
J4774_RS07530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4774_RS07535	COG4290	ribonuclease
J4774_RS07540	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J4774_RS07545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4774_RS07555	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J4774_RS07565	COG1051	belongs to the nudix hydrolase family
J4774_RS07570	COG0492	ferredoxin-NADP+ reductase activity
J4774_RS07575	COG0791	NLP P60 protein
J4774_RS07575	COG3883	PFAM NLP P60 protein
J4774_RS07580	COG0457	Tetratricopeptide repeat
J4774_RS07585	COG5002	protein histidine kinase activity
J4774_RS07590	COG0745	RESPONSE REGULATOR receiver
J4774_RS07600	COG1132	(ABC) transporter
J4774_RS07605	COG0140	phosphoribosyl-ATP diphosphatase activity
J4774_RS07605	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J4774_RS07630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4774_RS07645	COG4990	cell redox homeostasis
J4774_RS07650	COG0110	maltose O-acetyltransferase activity
J4774_RS07670	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J4774_RS07680	COG2188	Transcriptional regulator
J4774_RS07685	COG1309	transcriptional regulator
J4774_RS07690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J4774_RS07695	COG1950	PFAM Membrane protein of
J4774_RS07700	COG1983	PspC domain protein
J4774_RS07705	COG3595	metallopeptidase activity
J4774_RS07720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J4774_RS07730	COG4897	Protein conserved in bacteria
J4774_RS07735	COG0574	Belongs to the PEP-utilizing enzyme family
J4774_RS07735	COG3848	Pyruvate phosphate dikinase
J4774_RS07740	COG1309	transcriptional regulator
J4774_RS07745	COG2814	Major facilitator Superfamily
J4774_RS07760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4774_RS07770	COG3409	Peptidoglycan-binding domain 1 protein
J4774_RS07770	COG0793	Belongs to the peptidase S41A family
J4774_RS07775	COG3420	alginic acid biosynthetic process
J4774_RS07780	COG2177	Part of the ABC transporter FtsEX involved in
J4774_RS07785	COG2884	Cell division ATP-binding protein ftsE
J4774_RS07790	COG2010	Cytochrome c
J4774_RS07795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4774_RS07810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4774_RS07825	COG1516	flagellar protein fliS
J4774_RS07830	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4774_RS07835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4774_RS07855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4774_RS07860	COG1256	bacterial-type flagellum assembly
J4774_RS07860	COG4786	Flagellar basal body rod
J4774_RS07865	COG3418	PFAM FlgN family protein
J4774_RS07870	COG2747	anti-sigma28 factor FlgM
J4774_RS07880	COG1040	competence protein
J4774_RS07890	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
J4774_RS07895	COG1307	EDD domain protein, DegV family
J4774_RS07900	COG2197	response regulator
J4774_RS07905	COG4585	Histidine kinase
J4774_RS07910	COG1739	Uncharacterized protein family UPF0029
J4774_RS07915	COG1316	TRANSCRIPTIONal
J4774_RS07920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J4774_RS07925	COG0438	transferase activity, transferring glycosyl groups
J4774_RS07930	COG1215	transferase activity, transferring glycosyl groups
J4774_RS07935	COG3206	protein involved in exopolysaccharide biosynthesis
J4774_RS07940	COG3307	-O-antigen
J4774_RS07945	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J4774_RS07950	COG0297	glycogen (starch) synthase activity
J4774_RS07950	COG0438	transferase activity, transferring glycosyl groups
J4774_RS07955	COG2244	polysaccharide biosynthetic process
J4774_RS07965	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4774_RS07965	COG2247	cell wall binding repeat
J4774_RS07970	COG2247	cell wall binding repeat
J4774_RS07970	COG2385	sporulation resulting in formation of a cellular spore
J4774_RS07980	COG1316	TRANSCRIPTIONal
J4774_RS07985	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J4774_RS07990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J4774_RS07995	COG1134	teichoic acid transport
J4774_RS08000	COG1682	transport, permease protein
J4774_RS08005	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J4774_RS08015	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J4774_RS08020	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J4774_RS08025	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J4774_RS08030	COG4193	domain, Protein
J4774_RS08035	COG1482	cell wall glycoprotein biosynthetic process
J4774_RS08040	COG0697	spore germination
J4774_RS08045	COG0814	amino acid
J4774_RS08055	COG1215	transferase activity, transferring glycosyl groups
J4774_RS08060	COG2814	Major facilitator Superfamily
J4774_RS08065	COG1316	TRANSCRIPTIONal
J4774_RS08070	COG0561	phosphatase activity
J4774_RS08075	COG2433	Pfam Transposase IS66
J4774_RS08080	COG0791	NLP P60 protein
J4774_RS08090	COG2843	Capsule synthesis protein
J4774_RS08100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J4774_RS08105	COG0697	spore germination
J4774_RS08110	COG0814	amino acid
J4774_RS08120	COG1609	Transcriptional regulator
J4774_RS08125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4774_RS08135	COG1129	ABC transporter
J4774_RS08140	COG1172	Belongs to the binding-protein-dependent transport system permease family
J4774_RS08145	COG1879	ABC-type sugar transport system periplasmic component
J4774_RS08150	COG3103	Sh3 type 3 domain protein
J4774_RS08155	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4774_RS08160	COG3527	Alpha-acetolactate decarboxylase
J4774_RS08165	COG0028	Belongs to the TPP enzyme family
J4774_RS08170	COG0583	DNA-binding transcription factor activity
J4774_RS08175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J4774_RS08190	COG5337	Spore coat protein CotH
J4774_RS08200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J4774_RS08210	COG0405	Gamma-glutamyltransferase
J4774_RS08215	COG1522	sequence-specific DNA binding
J4774_RS08220	COG2059	Chromate
J4774_RS08225	COG2059	Chromate
J4774_RS08235	COG0655	NAD(P)H dehydrogenase (quinone) activity
J4774_RS08240	COG0583	DNA-binding transcription factor activity
J4774_RS08285	COG3878	Protein conserved in bacteria
J4774_RS08290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J4774_RS08295	COG4464	protein tyrosine phosphatase activity
J4774_RS08300	COG0489	protein tyrosine kinase activity
J4774_RS08305	COG3944	biosynthesis protein
J4774_RS08315	COG4715	Zinc finger, swim domain protein
J4774_RS08320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J4774_RS08325	COG0561	phosphatase activity
J4774_RS08330	COG1349	DNA-binding transcription factor activity
J4774_RS08335	COG0629	single-stranded DNA binding
J4774_RS08360	COG0457	Tetratricopeptide repeat
J4774_RS08365	COG4786	Flagellar basal body rod
J4774_RS08370	COG4786	Flagellar basal body rod
J4774_RS08375	COG1077	Cell shape determining protein MreB Mrl
J4774_RS08380	COG1609	Transcriptional regulator
J4774_RS08385	COG1846	Transcriptional regulator
J4774_RS08390	COG2814	Major facilitator Superfamily
J4774_RS08395	COG1953	Uracil, thiamine, allantoin
J4774_RS08400	COG0477	Major facilitator Superfamily
J4774_RS08405	COG1335	isochorismatase
J4774_RS08410	COG0004	ammonium transporteR
J4774_RS08415	COG0347	Belongs to the P(II) protein family
J4774_RS08420	COG0772	Belongs to the SEDS family
J4774_RS08425	COG0671	phosphoesterase, PA-phosphatase related
J4774_RS08435	COG0739	heme binding
J4774_RS08440	COG1247	-acetyltransferase
J4774_RS08455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4774_RS08465	COG0726	polysaccharide deacetylase
J4774_RS08470	COG1959	2 iron, 2 sulfur cluster binding
J4774_RS08485	COG0831	urea catabolic process
J4774_RS08490	COG3237	CsbD-like
J4774_RS08495	COG1994	Peptidase M50
J4774_RS08500	COG0457	Tetratricopeptide repeat
J4774_RS08510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J4774_RS08520	COG2304	oxidoreductase activity
J4774_RS08525	COG2304	oxidoreductase activity
J4774_RS08530	COG2385	sporulation resulting in formation of a cellular spore
J4774_RS08535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J4774_RS08545	COG4836	Membrane
J4774_RS08615	COG0698	ribose 5-phosphate isomerase
J4774_RS08620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4774_RS08630	COG0009	L-threonylcarbamoyladenylate synthase
J4774_RS08635	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4774_RS08655	COG2890	protein-(glutamine-N5) methyltransferase activity
J4774_RS08660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J4774_RS08665	COG0346	lactoylglutathione lyase activity
J4774_RS08670	COG0789	Transcriptional regulator
J4774_RS08675	COG0679	Auxin Efflux Carrier
J4774_RS08680	COG0281	malic enzyme
J4774_RS08695	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J4774_RS08700	COG1494	fructose-1,6-bisphosphatase
J4774_RS08705	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J4774_RS08715	COG0191	fructose-bisphosphate aldolase activity
J4774_RS08720	COG2204	response regulator
J4774_RS08725	COG4821	SIS domain
J4774_RS08740	COG2181	nitrate reductase activity
J4774_RS08740	COG0247	lactate metabolic process
J4774_RS08745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4774_RS08760	COG1132	(ABC) transporter
J4774_RS08765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4774_RS08775	COG2181	nitrate reductase activity
J4774_RS08780	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
J4774_RS08785	COG1140	nitrate reductase beta subunit
J4774_RS08790	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
J4774_RS08795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4774_RS08805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4774_RS08810	COG2223	nitrite transmembrane transporter activity
J4774_RS08820	COG4506	Protein conserved in bacteria
J4774_RS08825	COG0457	Tetratricopeptide repeat
J4774_RS08860	COG0010	Belongs to the arginase family
J4774_RS08865	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J4774_RS08870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4774_RS08885	COG1994	Peptidase M50
J4774_RS08890	COG1942	4-Oxalocrotonate Tautomerase
J4774_RS08895	COG1846	Transcriptional regulator
J4774_RS08900	COG0531	amino acid
J4774_RS08905	COG3465	dGTPase activity
J4774_RS08910	COG1078	dGTPase activity
J4774_RS08925	COG1695	Transcriptional regulator
J4774_RS08935	COG1131	(ABC) transporter
J4774_RS08940	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J4774_RS08970	COG0583	DNA-binding transcription factor activity
J4774_RS08975	COG2855	membrane
J4774_RS08980	COG0280	phosphate acetyltransferase
J4774_RS08990	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS08995	COG0436	Aminotransferase
J4774_RS09025	COG2814	Major facilitator Superfamily
J4774_RS09030	COG2814	Major facilitator Superfamily
J4774_RS09035	COG0833	amino acid
J4774_RS09040	COG4187	Peptidase family M20/M25/M40
J4774_RS09045	COG1012	belongs to the aldehyde dehydrogenase family
J4774_RS09050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J4774_RS09060	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
J4774_RS09065	COG1091	dTDP-4-dehydrorhamnose reductase activity
J4774_RS09070	COG1088	dTDP-glucose 4,6-dehydratase activity
J4774_RS09075	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J4774_RS09080	COG3980	spore coat polysaccharide biosynthesis protein
J4774_RS09085	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
J4774_RS09090	COG2089	acid synthase
J4774_RS09095	COG0456	acetyltransferase
J4774_RS09100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4774_RS09105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
J4774_RS09110	COG0463	Glycosyl transferase, family 2
J4774_RS09120	COG2363	Small membrane protein
J4774_RS09125	COG2233	PERMEase
J4774_RS09140	COG1216	Glycosyl transferase, family 2
J4774_RS09155	COG1695	Transcriptional regulator
J4774_RS09160	COG0351	phosphomethylpyrimidine kinase
J4774_RS09170	COG1621	beta-fructofuranosidase activity
J4774_RS09175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4774_RS09175	COG1263	PTS System
J4774_RS09180	COG3711	transcriptional antiterminator
J4774_RS09190	COG1404	Belongs to the peptidase S8 family
J4774_RS09195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4774_RS09200	COG0778	Nitroreductase
J4774_RS09205	COG0772	Belongs to the SEDS family
J4774_RS09210	COG0454	-acetyltransferase
J4774_RS09230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4774_RS09235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4774_RS09240	COG2261	transglycosylase associated protein
J4774_RS09245	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
J4774_RS09255	COG2246	polysaccharide biosynthetic process
J4774_RS09260	COG1309	transcriptional regulator
J4774_RS09280	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J4774_RS09285	COG2837	iron assimilation
J4774_RS09290	COG2822	iron ion transport
J4774_RS09310	COG0583	DNA-binding transcription factor activity
J4774_RS09320	COG1346	cytolysis
J4774_RS09325	COG4895	conserved protein (DUF2196)
J4774_RS09330	COG0789	Transcriptional regulator
J4774_RS09335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4774_RS09340	COG0346	lactoylglutathione lyase activity
J4774_RS09345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4774_RS09350	COG1404	Belongs to the peptidase S8 family
J4774_RS09355	COG1442	glycosyl transferase family 8
J4774_RS09360	COG2357	RelA SpoT domain protein
J4774_RS09365	COG1575	Belongs to the MenA family. Type 1 subfamily
J4774_RS09380	COG1696	Membrane protein involved in D-alanine export
J4774_RS09390	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
J4774_RS09395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4774_RS09400	COG1486	melibiose metabolic process
J4774_RS09405	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4774_RS09410	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4774_RS09415	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4774_RS09420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4774_RS09420	COG3711	transcriptional antiterminator
J4774_RS09430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4774_RS09435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4774_RS09445	COG0640	Transcriptional regulator
J4774_RS09450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J4774_RS09455	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4774_RS09460	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4774_RS09465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4774_RS09470	COG2723	6-phospho-beta-galactosidase activity
J4774_RS09475	COG1940	carbohydrate kinase activity
J4774_RS09480	COG1482	cell wall glycoprotein biosynthetic process
J4774_RS09490	COG0753	catalase activity
J4774_RS09495	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
J4774_RS09500	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J4774_RS09505	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J4774_RS09510	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J4774_RS09515	COG4988	ABC transporter
J4774_RS09520	COG1294	oxidase, subunit
J4774_RS09525	COG1271	oxidase subunit
J4774_RS09530	COG3493	citrate carrier protein
J4774_RS09535	COG0726	polysaccharide deacetylase
J4774_RS09540	COG3842	ATPase activity
J4774_RS09545	COG2508	Transcriptional regulator
J4774_RS09550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4774_RS09560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4774_RS09575	COG4894	glucomannan catabolic process
J4774_RS09580	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J4774_RS09585	COG0500	methyltransferase
J4774_RS09590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4774_RS09605	COG0693	protein deglycase activity
J4774_RS09605	COG0753	catalase activity
J4774_RS09610	COG2851	Citrate transporter
J4774_RS09615	COG2273	Hydrolase Family 16
J4774_RS09625	COG2270	Major facilitator Superfamily
J4774_RS09630	COG0513	Belongs to the DEAD box helicase family
J4774_RS09715	COG0697	spore germination
J4774_RS09720	COG0589	response to stress
J4774_RS09730	COG0494	nUDIX hydrolase
J4774_RS09735	COG3507	Belongs to the glycosyl hydrolase 43 family
J4774_RS09760	COG0010	Belongs to the arginase family
J4774_RS09765	COG0833	amino acid
J4774_RS09770	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J4774_RS09775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4774_RS09785	COG2390	Transcriptional regulator
J4774_RS09790	COG0561	phosphatase activity
J4774_RS09820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4774_RS09825	COG5294	Protein conserved in bacteria
J4774_RS09830	COG0577	efflux transmembrane transporter activity
J4774_RS09835	COG1136	(ABC) transporter
J4774_RS09840	COG2205	protein histidine kinase activity
J4774_RS09845	COG0745	RESPONSE REGULATOR receiver
J4774_RS09860	COG1082	Xylose isomerase domain protein TIM barrel
J4774_RS09870	COG2814	Major facilitator Superfamily
J4774_RS09900	COG1349	DNA-binding transcription factor activity
J4774_RS09905	COG0667	Aldo Keto reductase
J4774_RS09910	COG2814	Major facilitator Superfamily
J4774_RS09920	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS09925	COG2197	response regulator
J4774_RS09930	COG4585	Histidine kinase
J4774_RS09935	COG3239	Fatty acid desaturase
J4774_RS09940	COG1309	transcriptional regulator
J4774_RS09945	COG1012	belongs to the aldehyde dehydrogenase family
J4774_RS09950	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4774_RS09960	COG0640	Transcriptional regulator
J4774_RS09965	COG2814	Major facilitator Superfamily
J4774_RS09970	COG1714	RDD family
J4774_RS09980	COG0450	alkyl hydroperoxide reductase
J4774_RS09985	COG3634	alkyl hydroperoxide reductase activity
J4774_RS09990	COG3177	Filamentation induced by cAMP protein fic
J4774_RS09995	COG1113	amino acid transport
J4774_RS10005	COG2080	2 iron, 2 sulfur cluster binding
J4774_RS10020	COG2068	MobA-Related Protein
J4774_RS10025	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
J4774_RS10090	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
J4774_RS10095	COG0667	Aldo Keto reductase
J4774_RS10100	COG0456	acetyltransferase
J4774_RS10105	COG0457	Tetratricopeptide repeat
J4774_RS10110	COG0010	Belongs to the arginase family
J4774_RS10115	COG0833	amino acid
J4774_RS10120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4774_RS10125	COG5658	integral membrane protein
J4774_RS10130	COG0640	Transcriptional regulator
J4774_RS10135	COG3829	transcription factor binding
J4774_RS10145	COG0488	(ABC) transporter
J4774_RS10160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4774_RS10165	COG5002	protein histidine kinase activity
J4774_RS10175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4774_RS10180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J4774_RS10185	COG4853	Protein conserved in bacteria
J4774_RS10190	COG4863	YycH protein
J4774_RS10195	COG5002	protein histidine kinase activity
J4774_RS10200	COG0745	RESPONSE REGULATOR receiver
J4774_RS10230	COG0346	lactoylglutathione lyase activity
J4774_RS10235	COG0305	Participates in initiation and elongation during chromosome replication
J4774_RS10250	COG3093	addiction module antidote protein HigA
J4774_RS10255	COG0297	glycogen (starch) synthase activity
J4774_RS10265	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J4774_RS10270	COG0438	transferase activity, transferring glycosyl groups
J4774_RS10290	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
J4774_RS10295	COG4241	membrane
J4774_RS10305	COG5577	PFAM Coat F domain
J4774_RS10310	COG1733	regulation of RNA biosynthetic process
J4774_RS10320	COG0697	spore germination
J4774_RS10325	COG1621	beta-fructofuranosidase activity
J4774_RS10330	COG1621	beta-fructofuranosidase activity
J4774_RS10335	COG1802	Transcriptional regulator
J4774_RS10340	COG2318	DinB family
J4774_RS10345	COG2211	Major facilitator Superfamily
J4774_RS10355	COG0778	Nitroreductase
J4774_RS10360	COG1846	Transcriptional regulator
J4774_RS10365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4774_RS10370	COG1846	Transcriptional regulator
J4774_RS10390	COG0583	DNA-binding transcription factor activity
J4774_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS10400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4774_RS10405	COG0697	spore germination
J4774_RS10410	COG1331	Highly conserved protein containing a thioredoxin domain
J4774_RS10415	COG0789	Transcriptional regulator
J4774_RS10415	COG4978	Transcriptional regulator
J4774_RS10420	COG1811	Na channel or pump
J4774_RS10425	COG1331	Highly conserved protein containing a thioredoxin domain
J4774_RS10430	COG1331	Highly conserved protein containing a thioredoxin domain
J4774_RS10435	COG1266	CAAX protease self-immunity
J4774_RS10440	COG0477	Major facilitator Superfamily
J4774_RS10440	COG2814	Major facilitator Superfamily
J4774_RS10445	COG0346	lactoylglutathione lyase activity
J4774_RS10450	COG1609	Transcriptional regulator
J4774_RS10455	COG0708	Exodeoxyribonuclease III
J4774_RS10460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J4774_RS10465	COG2169	Transcriptional regulator
J4774_RS10475	COG0629	single-stranded DNA binding
J4774_RS10485	COG0012	GTP binding
J4774_RS10490	COG0243	molybdopterin cofactor binding
J4774_RS10495	COG4481	Protein conserved in bacteria
J4774_RS10500	COG3949	Membrane
J4774_RS10515	COG1475	DNA binding
J4774_RS10520	COG1192	Involved in chromosome partitioning
J4774_RS10545	COG1847	R3H domain protein
J4774_RS10550	COG0706	membrane insertase activity
J4774_RS10570	COG0592	DNA-directed DNA polymerase activity
J4774_RS10575	COG2501	S4 domain
J4774_RS10590	COG0187	DNA topoisomerase II activity
J4774_RS10595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J4774_RS10630	COG0516	GMP reductase activity
J4774_RS10630	COG0517	IMP dehydrogenase activity
J4774_RS10635	COG1686	Belongs to the peptidase S11 family
J4774_RS10655	COG1929	Belongs to the glycerate kinase type-1 family
J4774_RS10665	COG1428	Deoxynucleoside kinase
J4774_RS10670	COG1428	Deoxynucleoside kinase
J4774_RS10675	COG1388	LysM domain
J4774_RS10675	COG3858	chitin binding
J4774_RS10680	COG1335	isochorismatase
J4774_RS10685	COG0590	tRNA wobble adenosine to inosine editing
J4774_RS10695	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J4774_RS10700	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J4774_RS10750	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
J4774_RS10755	COG3853	Toxic anion resistance protein (TelA)
J4774_RS10760	COG1982	Orn Lys Arg decarboxylase major
J4774_RS10770	COG3870	Protein conserved in bacteria
J4774_RS10775	COG1728	Protein conserved in bacteria
J4774_RS10780	COG0470	DNA polymerase III
J4774_RS10785	COG1774	PSP1 C-terminal conserved region
J4774_RS10795	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J4774_RS10805	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J4774_RS10810	COG2002	toxin-antitoxin pair type II binding
J4774_RS10815	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4774_RS10815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4774_RS10820	COG0084	hydrolase, TatD family'
J4774_RS10825	COG3583	domain protein
J4774_RS10825	COG3584	3D domain protein
J4774_RS10830	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J4774_RS10835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J4774_RS10845	COG4466	Protein conserved in bacteria
J4774_RS10860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J4774_RS10865	COG0251	oxidation-reduction process
J4774_RS10880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J4774_RS10900	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J4774_RS10905	COG2002	toxin-antitoxin pair type II binding
J4774_RS10910	COG2244	polysaccharide biosynthetic process
J4774_RS10915	COG3956	TIGRFAM MazG family protein
J4774_RS10920	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J4774_RS10935	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J4774_RS10940	COG1098	S1 RNA binding domain
J4774_RS10955	COG2208	phosphoserine phosphatase activity
J4774_RS10960	COG2304	oxidoreductase activity
J4774_RS10965	COG0515	serine threonine protein kinase
J4774_RS10970	COG0037	tRNA processing
J4774_RS10975	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J4774_RS10980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4774_RS10995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4774_RS11000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4774_RS11005	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4774_RS11010	COG0512	Glutamine amidotransferase of anthranilate synthase
J4774_RS11015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4774_RS11020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J4774_RS11025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4774_RS11030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4774_RS11035	COG1396	sequence-specific DNA binding
J4774_RS11040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4774_RS11045	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J4774_RS11125	COG4463	regulation of RNA biosynthetic process
J4774_RS11130	COG3880	PFAM UvrB UvrC protein
J4774_RS11140	COG0542	response to heat
J4774_RS11145	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J4774_RS11150	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
J4774_RS11155	COG4956	integral membrane protein (PIN domain superfamily)
J4774_RS11175	COG1045	serine acetyltransferase
J4774_RS11185	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
J4774_RS11190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4774_RS11195	COG3688	RNA-binding protein containing a PIN domain
J4774_RS11200	COG1595	DNA-templated transcription, initiation
J4774_RS11210	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4774_RS11215	COG0250	Participates in transcription elongation, termination and antitermination
J4774_RS11240	COG2813	Specifically methylates the guanine in position
J4774_RS11255	COG1358	cellular component organization or biogenesis
J4774_RS11280	COG0596	Alpha beta hydrolase
J4774_RS11390	COG0201	protein transport
J4774_RS11400	COG0024	Methionine aminopeptidase
J4774_RS11410	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4774_RS11435	COG1122	ATPase activity
J4774_RS11440	COG1122	ATPase activity
J4774_RS11445	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J4774_RS11465	COG2226	methyltransferase
J4774_RS11470	COG2318	DinB family
J4774_RS11480	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4774_RS11485	COG0489	protein tyrosine kinase activity
J4774_RS11495	COG2194	sulfuric ester hydrolase activity
J4774_RS11500	COG0726	polysaccharide deacetylase
J4774_RS11560	COG0738	Major facilitator superfamily
J4774_RS11565	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4774_RS11580	COG0659	secondary active sulfate transmembrane transporter activity
J4774_RS11585	COG0385	Bile acid
J4774_RS11590	COG2819	hydrolase of the alpha beta superfamily
J4774_RS11595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4774_RS11600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4774_RS11605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4774_RS11610	COG2207	Transcriptional regulator
J4774_RS11610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4774_RS11615	COG3876	Protein conserved in bacteria
J4774_RS11620	COG1472	Belongs to the glycosyl hydrolase 3 family
J4774_RS11625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J4774_RS11630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4774_RS11630	COG1263	PTS System
J4774_RS11640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4774_RS11645	COG1683	Conserved Protein
J4774_RS11675	COG1595	DNA-templated transcription, initiation
J4774_RS11680	COG5662	AntiSigma factor
J4774_RS11685	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J4774_RS11690	COG4856	YbbR-like protein
J4774_RS11740	COG1346	cytolysis
J4774_RS11745	COG1380	Effector of murein hydrolase LrgA
J4774_RS11750	COG1846	Transcriptional regulator
J4774_RS11755	COG1113	amino acid transport
J4774_RS11760	COG1011	Hydrolase
J4774_RS11765	COG4585	Histidine kinase
J4774_RS11770	COG2197	response regulator
J4774_RS11775	COG1131	(ABC) transporter
J4774_RS11815	COG0531	amino acid
J4774_RS11820	COG0584	glycerophosphoryl diester phosphodiesterase
J4774_RS11825	COG2271	Major facilitator Superfamily
J4774_RS11835	COG2368	4-hydroxyphenylacetate
J4774_RS11845	COG3409	Peptidoglycan-binding domain 1 protein
J4774_RS11860	COG0371	Dehydrogenase
J4774_RS11870	COG1183	phosphatidylcholine synthase activity
J4774_RS11875	COG0586	Pfam SNARE associated Golgi protein
J4774_RS11880	COG0688	phosphatidylethanolamine metabolic process
J4774_RS11895	COG1301	dicarboxylic acid transport
J4774_RS11900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4774_RS11905	COG0833	amino acid
J4774_RS11910	COG2040	homocysteine
J4774_RS11915	COG1115	amino acid carrier protein
J4774_RS11920	COG2066	Belongs to the glutaminase family
J4774_RS11925	COG4191	Histidine kinase
J4774_RS11930	COG0784	Response regulator, receiver
J4774_RS11935	COG3173	Aminoglycoside phosphotransferase
J4774_RS11945	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4774_RS11950	COG0778	Nitroreductase
J4774_RS11955	COG0346	lactoylglutathione lyase activity
J4774_RS11960	COG2259	Doxx family
J4774_RS11965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4774_RS11980	COG3773	Cell wall hydrolase
J4774_RS11985	COG3540	Alkaline phosphatase
J4774_RS11990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4774_RS11995	COG0805	protein transport
J4774_RS12005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4774_RS12010	COG0477	Major facilitator Superfamily
J4774_RS12015	COG1309	transcriptional regulator
J4774_RS12020	COG0252	asparaginase activity
J4774_RS12025	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J4774_RS12030	COG3012	SEC-C Motif Domain Protein
J4774_RS12030	COG1405	negative regulation of cell septum assembly
J4774_RS12035	COG0667	Aldo Keto reductase
J4774_RS12045	COG1595	DNA-templated transcription, initiation
J4774_RS12050	COG1595	DNA-templated transcription, initiation
J4774_RS12055	COG1876	peptidase activity
J4774_RS12060	COG0457	Tetratricopeptide repeat
J4774_RS12065	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS12070	COG0366	Alpha amylase catalytic
J4774_RS12080	COG1695	Transcriptional regulator
J4774_RS12085	COG0803	Belongs to the bacterial solute-binding protein 9 family
J4774_RS12090	COG1121	(ABC) transporter
J4774_RS12095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4774_RS12100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4774_RS12105	COG2310	stress, protein
J4774_RS12110	COG2310	stress, protein
J4774_RS12115	COG2310	stress, protein
J4774_RS12120	COG0861	Integral membrane protein TerC family
J4774_RS12130	COG3853	Toxic anion resistance protein (TelA)
J4774_RS12135	COG0477	Major facilitator Superfamily
J4774_RS12140	COG0517	IMP dehydrogenase activity
J4774_RS12140	COG4175	Glycine betaine
J4774_RS12145	COG4176	ABC-type proline glycine betaine transport system permease component
J4774_RS12150	COG2113	Glycine betaine
J4774_RS12155	COG1473	amidohydrolase
J4774_RS12160	COG1288	antiporter activity
J4774_RS12170	COG0366	Alpha amylase catalytic
J4774_RS12180	COG2814	Major facilitator Superfamily
J4774_RS12185	COG1846	Transcriptional regulator
J4774_RS12190	COG1280	lysine exporter protein (LysE YggA)
J4774_RS12195	COG3403	YqcI/YcgG family
J4774_RS12200	COG1113	amino acid transport
J4774_RS12205	COG3665	Urea carboxylase-associated protein
J4774_RS12220	COG1660	Displays ATPase and GTPase activities
J4774_RS12230	COG2271	Major facilitator Superfamily
J4774_RS12235	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J4774_RS12240	COG3458	cephalosporin-C deacetylase activity
J4774_RS12245	COG3541	Predicted nucleotidyltransferase
J4774_RS12250	COG0506	proline dehydrogenase activity
J4774_RS12255	COG1012	belongs to the aldehyde dehydrogenase family
J4774_RS12260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4774_RS12265	COG2508	Transcriptional regulator
J4774_RS12275	COG1587	Uroporphyrinogen-III synthase
J4774_RS12275	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4774_RS12280	COG2146	nitrite reductase [NAD(P)H] activity
J4774_RS12285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4774_RS12290	COG0523	cobalamin synthesis protein
J4774_RS12295	COG1063	alcohol dehydrogenase
J4774_RS12300	COG1714	RDD family
J4774_RS12310	COG2723	6-phospho-beta-galactosidase activity
J4774_RS12325	COG3209	COG3209 Rhs family protein
J4774_RS12330	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J4774_RS12335	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
J4774_RS12340	COG1733	regulation of RNA biosynthetic process
J4774_RS12345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS12350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS12355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS12360	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
J4774_RS12375	COG2364	Membrane
J4774_RS12380	COG1126	abc transporter atp-binding protein
J4774_RS12385	COG0765	amino acid transport
J4774_RS12390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4774_RS12395	COG0583	DNA-binding transcription factor activity
J4774_RS12400	COG0163	prenyltransferase activity
J4774_RS12405	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J4774_RS12420	COG3104	oligopeptide transport
J4774_RS12425	COG5434	Belongs to the glycosyl hydrolase 28 family
J4774_RS12435	COG0697	spore germination
J4774_RS12445	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J4774_RS12450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4774_RS12455	COG0456	acetyltransferase
J4774_RS12460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4774_RS12465	COG0765	amino acid transport
J4774_RS12470	COG1126	abc transporter atp-binding protein
J4774_RS12475	COG1473	amidohydrolase
J4774_RS12480	COG2079	MmgE PrpD family protein
J4774_RS12485	COG1136	(ABC) transporter
J4774_RS12490	COG0577	efflux transmembrane transporter activity
J4774_RS12495	COG0745	RESPONSE REGULATOR receiver
J4774_RS12500	COG3850	Histidine kinase
J4774_RS12500	COG5002	protein histidine kinase activity
J4774_RS12505	COG0457	Tetratricopeptide repeat
J4774_RS12520	COG0527	aspartate kinase activity
J4774_RS12525	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4774_RS12530	COG4605	iron ion homeostasis
J4774_RS12535	COG4604	ABC transporter, ATP-binding protein
J4774_RS12540	COG4607	ABC-type enterochelin transport system periplasmic component
J4774_RS12545	COG2814	Major facilitator Superfamily
J4774_RS12550	COG1309	transcriptional regulator
J4774_RS12555	COG0778	Nitroreductase
J4774_RS12560	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J4774_RS12565	COG0640	Transcriptional regulator
J4774_RS12570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4774_RS12575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4774_RS12580	COG1012	belongs to the aldehyde dehydrogenase family
J4774_RS12585	COG4975	Glucose uptake
J4774_RS12590	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS12595	COG4549	nuclear export factor GLE1
J4774_RS12600	COG1276	copper resistance
J4774_RS12600	COG2372	response to copper ion
J4774_RS12605	COG1349	DNA-binding transcription factor activity
J4774_RS12615	COG2213	PTS system mannitol-specific
J4774_RS12620	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4774_RS12630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4774_RS12640	COG0561	phosphatase activity
J4774_RS12650	COG1914	H( )-stimulated, divalent metal cation uptake system
J4774_RS12660	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J4774_RS12665	COG1984	allophanate hydrolase subunit 2
J4774_RS12670	COG1414	Transcriptional regulator
J4774_RS12675	COG2755	lipolytic protein G-D-S-L family
J4774_RS12685	COG2329	Antibiotic biosynthesis monooxygenase
J4774_RS12690	COG0768	penicillin binding
J4774_RS12695	COG4989	oxidoreductase activity
J4774_RS12700	COG3711	transcriptional antiterminator
J4774_RS12705	COG0318	PFAM AMP-dependent synthetase and ligase
J4774_RS12710	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS12715	COG1917	Cupin 2, conserved barrel domain protein
J4774_RS12720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4774_RS12725	COG3871	stress protein (general stress protein 26)
J4774_RS12735	COG2814	Major facilitator Superfamily
J4774_RS12740	COG1522	sequence-specific DNA binding
J4774_RS12745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4774_RS12745	COG0551	DNA topoisomerase type I activity
J4774_RS12750	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
J4774_RS12755	COG3706	GGDEF domain
J4774_RS12760	COG5298	Protein conserved in bacteria
J4774_RS12765	COG1215	transferase activity, transferring glycosyl groups
J4774_RS12775	COG0531	amino acid
J4774_RS12780	COG0494	nUDIX hydrolase
J4774_RS12785	COG0028	Belongs to the TPP enzyme family
J4774_RS12840	COG0457	Tetratricopeptide repeat
J4774_RS12860	COG1914	H( )-stimulated, divalent metal cation uptake system
J4774_RS12870	COG4876	unkown
J4774_RS12880	COG2076	Multidrug Resistance protein
J4774_RS12885	COG2217	Heavy metal translocating P-type atpase
J4774_RS12890	COG3729	General stress protein
J4774_RS12895	COG0662	Cupin 2, conserved barrel domain protein
J4774_RS12900	COG2329	Antibiotic biosynthesis monooxygenase
J4774_RS12905	COG3546	catalase activity
J4774_RS12910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4774_RS12915	COG3290	protein histidine kinase activity
J4774_RS12920	COG4565	transcriptional regulatory protein
J4774_RS12925	COG1301	dicarboxylic acid transport
J4774_RS12930	COG0628	permease
J4774_RS12935	COG1131	(ABC) transporter
J4774_RS12940	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J4774_RS12950	COG1960	acyl-CoA dehydrogenase activity
J4774_RS12965	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4774_RS12970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4774_RS12980	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4774_RS12985	COG0513	Belongs to the DEAD box helicase family
J4774_RS12990	COG3402	PFAM membrane-flanked domain
J4774_RS12995	COG3428	Bacterial PH domain
J4774_RS13000	COG0705	Rhomboid family
J4774_RS13010	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J4774_RS13015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4774_RS13020	COG0864	Transcriptional regulator
J4774_RS13025	COG2337	Toxic component of a toxin-antitoxin (TA) module
J4774_RS13030	COG1366	Belongs to the anti-sigma-factor antagonist family
J4774_RS13035	COG1366	Belongs to the anti-sigma-factor antagonist family
J4774_RS13040	COG2172	sigma factor antagonist activity
J4774_RS13045	COG2208	phosphoserine phosphatase activity
J4774_RS13050	COG1366	Belongs to the anti-sigma-factor antagonist family
J4774_RS13060	COG1191	sigma factor activity
J4774_RS13065	COG2208	phosphoserine phosphatase activity
J4774_RS13070	COG2183	response to ionizing radiation
J4774_RS13120	COG0457	Tetratricopeptide repeat
J4774_RS13125	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4774_RS13140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4774_RS13145	COG0477	Major facilitator Superfamily
J4774_RS13155	COG1764	response to oxidative stress
J4774_RS13160	COG1846	Transcriptional regulator
J4774_RS13170	COG1959	2 iron, 2 sulfur cluster binding
J4774_RS13175	COG2910	NAD(P)H-binding
J4774_RS13180	COG1278	Cold shock
J4774_RS13190	COG1937	Protein conserved in bacteria
J4774_RS13195	COG2210	Belongs to the sulfur carrier protein TusA family
J4774_RS13200	COG1054	Belongs to the UPF0176 family
J4774_RS13205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4774_RS13205	COG0425	Belongs to the sulfur carrier protein TusA family
J4774_RS13210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4774_RS13210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4774_RS13215	COG0425	Belongs to the sulfur carrier protein TusA family
J4774_RS13220	COG0730	response to heat
J4774_RS13225	COG1794	racemase activity, acting on amino acids and derivatives
J4774_RS13240	COG3621	Patatin-like phospholipase
J4774_RS13250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J4774_RS13255	COG1802	Transcriptional regulator
J4774_RS13260	COG0251	oxidation-reduction process
J4774_RS13265	COG0814	amino acid
J4774_RS13270	COG1473	amidohydrolase
J4774_RS13275	COG2207	Transcriptional regulator
J4774_RS13275	COG1917	Cupin 2, conserved barrel domain protein
J4774_RS13285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4774_RS13290	COG0477	Major facilitator Superfamily
J4774_RS13310	COG0277	FAD linked oxidase domain protein
J4774_RS13340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4774_RS13365	COG1064	alcohol dehydrogenase
J4774_RS13370	COG0789	Transcriptional regulator
J4774_RS13380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4774_RS13395	COG2814	Major facilitator Superfamily
J4774_RS13400	COG1309	transcriptional regulator
J4774_RS13405	COG5577	PFAM Coat F domain
J4774_RS13415	COG1063	alcohol dehydrogenase
J4774_RS13420	COG5577	PFAM Coat F domain
J4774_RS13430	COG4585	Histidine kinase
J4774_RS13435	COG2197	response regulator
J4774_RS13440	COG2409	Drug exporters of the RND superfamily
J4774_RS13445	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J4774_RS13450	COG0488	(ABC) transporter
J4774_RS13455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4774_RS13460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4774_RS13470	COG2814	Major facilitator Superfamily
J4774_RS13475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4774_RS13485	COG0730	response to heat
J4774_RS13490	COG0456	acetyltransferase
J4774_RS13495	COG4978	Transcriptional regulator
J4774_RS13495	COG0789	Transcriptional regulator
J4774_RS13500	COG0697	spore germination
J4774_RS13505	COG1051	belongs to the nudix hydrolase family
J4774_RS13510	COG2226	methyltransferase
J4774_RS13515	COG0473	3-isopropylmalate dehydrogenase activity
J4774_RS13520	COG1802	Transcriptional regulator
J4774_RS13525	COG1819	glycosyl
J4774_RS13540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J4774_RS13550	COG1388	LysM domain
J4774_RS13555	COG2814	Major facilitator Superfamily
J4774_RS13560	COG2188	Transcriptional regulator
J4774_RS13565	COG2186	Transcriptional regulator
J4774_RS13570	COG2807	transmembrane transport
J4774_RS13575	COG2076	Multidrug Resistance protein
J4774_RS13580	COG2076	Multidrug Resistance protein
J4774_RS13585	COG1309	transcriptional regulator
J4774_RS13590	COG0531	amino acid
J4774_RS13600	COG3832	glyoxalase III activity
J4774_RS13605	COG0604	alcohol dehydrogenase
J4774_RS13610	COG2814	Major facilitator Superfamily
J4774_RS13650	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J4774_RS13655	COG0802	atpase or kinase
J4774_RS13660	COG1214	PFAM Peptidase M22, glycoprotease
J4774_RS13665	COG0456	acetyltransferase
J4774_RS13670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J4774_RS13675	COG0488	(ABC) transporter
J4774_RS13690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4774_RS13695	COG0805	protein transport
J4774_RS13705	COG1266	CAAX protease self-immunity
J4774_RS13720	COG3409	Peptidoglycan-binding domain 1 protein
J4774_RS13735	COG0457	Tetratricopeptide repeat
J4774_RS13740	COG1063	alcohol dehydrogenase
J4774_RS13745	COG2211	Major facilitator Superfamily
J4774_RS13750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4774_RS13760	COG1842	Phage shock protein A
J4774_RS13765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4774_RS13770	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
J4774_RS13775	COG4260	virion core protein, lumpy skin disease virus
J4774_RS13780	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J4774_RS13780	COG2755	lipolytic protein G-D-S-L family
J4774_RS13790	COG1595	DNA-templated transcription, initiation
J4774_RS13795	COG1063	alcohol dehydrogenase
J4774_RS13800	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4774_RS13805	COG0823	Involved in the tonB-independent uptake of proteins
J4774_RS13820	COG2132	Multicopper oxidase
J4774_RS13825	COG1113	amino acid transport
J4774_RS13830	COG0714	Associated with various cellular activities
J4774_RS13835	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
J4774_RS13840	COG1305	Transglutaminase-like
J4774_RS13860	COG2252	PERMEase
J4774_RS13865	COG3064	Membrane
J4774_RS13885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J4774_RS13890	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J4774_RS13895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J4774_RS13900	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J4774_RS13905	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J4774_RS13920	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J4774_RS13930	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J4774_RS13935	COG0138	bifunctional purine biosynthesis protein purh
J4774_RS13940	COG0151	Belongs to the GarS family
J4774_RS13950	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J4774_RS13955	COG1470	cell adhesion involved in biofilm formation
J4774_RS13960	COG4496	protein, YerC YecD
J4774_RS13965	COG0069	glutamate synthase activity
J4774_RS13975	COG0210	DNA helicase
J4774_RS13985	COG4851	CamS sex pheromone cAM373 precursor
J4774_RS13990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4774_RS13995	COG1285	pathogenesis
J4774_RS14000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4774_RS14020	COG1309	transcriptional regulator
J4774_RS14025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4774_RS14030	COG1597	lipid kinase activity
J4774_RS14035	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4774_RS14040	COG2189	Belongs to the N(4) N(6)-methyltransferase family
J4774_RS14045	COG3421	Type III restriction
J4774_RS14080	COG5444	nuclease activity
J4774_RS14110	COG3546	catalase activity
J4774_RS14115	COG0454	-acetyltransferase
J4774_RS14125	COG2323	membrane
J4774_RS14130	COG2329	Antibiotic biosynthesis monooxygenase
J4774_RS14135	COG0346	lactoylglutathione lyase activity
J4774_RS14140	COG1366	Belongs to the anti-sigma-factor antagonist family
J4774_RS14145	COG5583	Uncharacterized small protein (DUF2292)
J4774_RS14150	COG0196	riboflavin kinase activity
J4774_RS14155	COG0670	Belongs to the BI1 family
J4774_RS14160	COG1846	Transcriptional regulator
J4774_RS14165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4774_RS14175	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4774_RS14175	COG2124	cytochrome p450
J4774_RS14180	COG1368	sulfuric ester hydrolase activity
J4774_RS14185	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J4774_RS14190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4774_RS14195	COG1442	glycosyl transferase family 8
J4774_RS14200	COG1216	Glycosyl transferase, family 2
J4774_RS14205	COG1442	glycosyl transferase family 8
J4774_RS14210	COG2223	nitrite transmembrane transporter activity
J4774_RS14215	COG0531	amino acid
J4774_RS14220	COG1012	belongs to the aldehyde dehydrogenase family
J4774_RS14225	COG0840	transmembrane signaling receptor activity
J4774_RS14230	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS14235	COG0463	Glycosyl transferase, family 2
J4774_RS14235	COG0457	Tetratricopeptide repeat
J4774_RS14240	COG0488	(ABC) transporter
J4774_RS14245	COG0789	Transcriptional regulator
J4774_RS14250	COG2814	Major facilitator Superfamily
J4774_RS14255	COG0488	(ABC) transporter
J4774_RS14260	COG0513	Belongs to the DEAD box helicase family
J4774_RS14265	COG0456	acetyltransferase
J4774_RS14270	COG2130	NADP-dependent
J4774_RS14285	COG3866	Pectate lyase
J4774_RS14290	COG0471	metal ion transport
J4774_RS14315	COG3290	protein histidine kinase activity
J4774_RS14320	COG4565	transcriptional regulatory protein
J4774_RS14325	COG3181	Tripartite tricarboxylate transporter family receptor
J4774_RS14330	COG2851	Citrate transporter
J4774_RS14335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4774_RS14340	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
J4774_RS14350	COG2258	MOSC domain
J4774_RS14370	COG0024	Methionine aminopeptidase
J4774_RS14375	COG1263	PTS System
J4774_RS14375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4774_RS14385	COG1368	sulfuric ester hydrolase activity
J4774_RS14395	COG0071	Belongs to the small heat shock protein (HSP20) family
J4774_RS14410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4774_RS14410	COG1263	PTS System
J4774_RS14415	COG0366	Alpha amylase catalytic
J4774_RS14420	COG2188	Transcriptional regulator
J4774_RS14425	COG0778	Nitroreductase
J4774_RS14440	COG0737	Belongs to the 5'-nucleotidase family
J4774_RS14445	COG0693	protein deglycase activity
J4774_RS14450	COG1609	Transcriptional regulator
J4774_RS14465	COG2814	Major facilitator Superfamily
J4774_RS14475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4774_RS14480	COG4980	gas vesicle protein
J4774_RS14485	COG1295	ribonuclease BN
J4774_RS14490	COG0477	Major facilitator Superfamily
J4774_RS14495	COG0387	Pfam Sodium calcium exchanger
J4774_RS14505	COG0668	transmembrane transport
J4774_RS14510	COG0535	radical SAM domain protein
J4774_RS14520	COG0726	polysaccharide deacetylase
J4774_RS14525	COG2084	Dehydrogenase
J4774_RS14535	COG0598	Magnesium transport protein CorA
J4774_RS14540	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J4774_RS14545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4774_RS14555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4774_RS14560	COG4637	Psort location Cytoplasmic, score
J4774_RS14565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J4774_RS14570	COG0022	dehydrogenase e1 component
J4774_RS14575	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4774_RS14580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4774_RS14585	COG3284	Transcriptional regulator
J4774_RS14595	COG1486	melibiose metabolic process
J4774_RS14600	COG1737	Transcriptional regulator
J4774_RS14605	COG1263	PTS System
J4774_RS14605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4774_RS14610	COG1132	(ABC) transporter
J4774_RS14615	COG1132	(ABC) transporter
J4774_RS14620	COG2259	Doxx family
J4774_RS14625	COG2514	catechol 2,3-dioxygenase activity
J4774_RS14635	COG1695	Transcriptional regulator
J4774_RS14640	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4774_RS14645	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
J4774_RS14650	COG3848	Pyruvate phosphate dikinase
J4774_RS14650	COG0574	Belongs to the PEP-utilizing enzyme family
J4774_RS14655	COG2732	(Barnase) inhibitor
J4774_RS14660	COG2318	DinB family
J4774_RS14665	COG2814	Major facilitator Superfamily
J4774_RS14670	COG1846	Transcriptional regulator
J4774_RS14675	COG0392	lysyltransferase activity
J4774_RS14675	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
J4774_RS14680	COG0384	phenazine biosynthesis protein PhzF
J4774_RS14685	COG0778	Nitroreductase
J4774_RS14700	COG1090	epimerase
J4774_RS14715	COG2814	Major facilitator Superfamily
J4774_RS14725	COG3591	Belongs to the peptidase S1B family
J4774_RS14740	COG3103	Sh3 type 3 domain protein
J4774_RS14745	COG5658	integral membrane protein
J4774_RS14750	COG0596	Alpha beta hydrolase
J4774_RS14755	COG0463	Glycosyl transferase, family 2
J4774_RS14760	COG4485	Bacterial membrane protein, YfhO
J4774_RS14765	COG1988	membrane-bound metal-dependent
J4774_RS14770	COG1194	a g-specific adenine glycosylase
J4774_RS14780	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS14800	COG1132	(ABC) transporter
J4774_RS14805	COG4129	membrane
J4774_RS14815	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J4774_RS14820	COG0735	belongs to the Fur family
J4774_RS14935	COG3340	Belongs to the peptidase S51 family
J4774_RS14945	COG0277	FAD linked oxidase domain protein
J4774_RS14955	COG0747	negative chemotaxis
J4774_RS14960	COG0601	transmembrane transport
J4774_RS14965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4774_RS14970	COG0444	Belongs to the ABC transporter superfamily
J4774_RS14975	COG4608	Belongs to the ABC transporter superfamily
J4774_RS14980	COG0753	catalase activity
J4774_RS14990	COG1116	anion transmembrane transporter activity
J4774_RS14995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4774_RS15000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4774_RS15020	COG1476	TRANSCRIPTIONal
J4774_RS15030	COG3382	B3 4 domain protein
J4774_RS15035	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J4774_RS15045	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J4774_RS15050	COG0789	Transcriptional regulator
J4774_RS15055	COG1664	Polymer-forming cytoskeletal
J4774_RS15060	COG1664	Polymer-forming cytoskeletal
J4774_RS15065	COG2766	serine protein kinase
J4774_RS15075	COG1846	Transcriptional regulator
J4774_RS15080	COG1566	PFAM secretion protein HlyD family protein
J4774_RS15085	COG2814	Major facilitator Superfamily
J4774_RS15090	COG0655	NAD(P)H dehydrogenase (quinone) activity
J4774_RS15105	COG1725	Transcriptional regulator
J4774_RS15110	COG1131	(ABC) transporter
J4774_RS15115	COG1131	(ABC) transporter
J4774_RS15120	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J4774_RS15125	COG1278	Cold shock
J4774_RS15130	COG1464	Belongs to the NlpA lipoprotein family
J4774_RS15135	COG3706	GGDEF domain
J4774_RS15140	COG1823	symporter activity
J4774_RS15160	COG5577	PFAM Coat F domain
J4774_RS15165	COG4085	toxin activity
J4774_RS15165	COG1525	nuclease
J4774_RS15165	COG0737	Belongs to the 5'-nucleotidase family
J4774_RS15170	COG3764	Sortase (surface protein transpeptidase)
J4774_RS15175	COG0564	pseudouridine synthase activity
J4774_RS15185	COG0517	IMP dehydrogenase activity
J4774_RS15190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4774_RS15195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4774_RS15195	COG3153	acetyltransferase
J4774_RS15200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4774_RS15205	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
J4774_RS15210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4774_RS15220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4774_RS15225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4774_RS15230	COG2203	Gaf domain
J4774_RS15230	COG4585	Histidine kinase
J4774_RS15235	COG2197	response regulator
J4774_RS15240	COG0431	NADPH-dependent FMN reductase
J4774_RS15255	COG0791	NLP P60 protein
J4774_RS15255	COG1388	LysM domain
J4774_RS15260	COG1959	2 iron, 2 sulfur cluster binding
J4774_RS15265	COG0668	transmembrane transport
J4774_RS15270	COG2719	SpoVR family
J4774_RS15275	COG1785	Belongs to the alkaline phosphatase family
J4774_RS15280	COG0791	NLP P60 protein
J4774_RS15280	COG1388	LysM domain
J4774_RS15285	COG0583	DNA-binding transcription factor activity
J4774_RS15290	COG0372	Belongs to the citrate synthase family
J4774_RS15295	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS15300	COG0531	amino acid
J4774_RS15305	COG0733	neurotransmitter:sodium symporter activity
J4774_RS15320	COG1595	DNA-templated transcription, initiation
J4774_RS15325	COG0204	Acyl-transferase
J4774_RS15330	COG1253	flavin adenine dinucleotide binding
J4774_RS15335	COG0789	Transcriptional regulator
J4774_RS15340	COG0436	Aminotransferase
J4774_RS15345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4774_RS15350	COG1253	flavin adenine dinucleotide binding
J4774_RS15355	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J4774_RS15360	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J4774_RS15365	COG0584	glycerophosphoryl diester phosphodiesterase
J4774_RS15375	COG0668	transmembrane transport
J4774_RS15380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4774_RS15385	COG0726	polysaccharide deacetylase
J4774_RS15390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4774_RS15395	COG3226	Transcriptional regulator
J4774_RS15405	COG0589	response to stress
J4774_RS15410	COG1132	(ABC) transporter
J4774_RS15415	COG1132	(ABC) transporter
J4774_RS15420	COG0702	epimerase
J4774_RS15435	COG0189	ligase activity
J4774_RS15440	COG0189	ligase activity
J4774_RS15455	COG4335	DNA alkylation repair
J4774_RS15460	COG0561	phosphatase activity
J4774_RS15465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4774_RS15475	COG0475	glutathione-regulated potassium exporter activity
J4774_RS15480	COG0490	domain, Protein
J4774_RS15490	COG1024	Enoyl-CoA hydratase
J4774_RS15500	COG4152	abc transporter atp-binding protein
J4774_RS15505	COG1668	transmembrane transport
J4774_RS15510	COG0420	3'-5' exonuclease activity
J4774_RS15515	COG4717	serine-type aminopeptidase activity
J4774_RS15530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4774_RS15565	COG4980	gas vesicle protein
J4774_RS15580	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J4774_RS15585	COG0537	adenosine 5'-monophosphoramidase activity
J4774_RS15590	COG1131	(ABC) transporter
J4774_RS15595	COG4473	ABC transporter
J4774_RS15605	COG1473	amidohydrolase
J4774_RS15610	COG3069	C4-dicarboxylate transmembrane transporter activity
J4774_RS15615	COG2329	Antibiotic biosynthesis monooxygenase
J4774_RS15620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4774_RS15630	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J4774_RS15635	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
J4774_RS15640	COG1309	transcriptional regulator
J4774_RS15645	COG1511	domain protein
J4774_RS15650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4774_RS15660	COG1363	Peptidase, m42
J4774_RS15665	COG1301	dicarboxylic acid transport
J4774_RS15675	COG1234	tRNA 3'-trailer cleavage
J4774_RS15680	COG0095	Lipoate-protein ligase
J4774_RS15685	COG0702	epimerase
J4774_RS15690	COG0318	PFAM AMP-dependent synthetase and ligase
J4774_RS15700	COG0501	Belongs to the peptidase M48B family
J4774_RS15705	COG1404	Belongs to the peptidase S8 family
J4774_RS15710	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J4774_RS15715	COG0406	alpha-ribazole phosphatase activity
J4774_RS15720	COG0183	Belongs to the thiolase family
J4774_RS15725	COG0318	PFAM AMP-dependent synthetase and ligase
J4774_RS15730	COG1268	BioY protein
J4774_RS15735	COG0840	transmembrane signaling receptor activity
J4774_RS15740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4774_RS15740	COG0723	plastoquinol--plastocyanin reductase activity
J4774_RS15745	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS15755	COG4903	ComK protein
J4774_RS15765	COG5646	InterPro IPR014922
J4774_RS15785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4774_RS15800	COG0398	Pfam SNARE associated Golgi protein
J4774_RS15805	COG0681	Belongs to the peptidase S26 family
J4774_RS15810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4774_RS15815	COG1846	Transcriptional regulator
J4774_RS15820	COG3180	Ammonia monooxygenase
J4774_RS15825	COG2814	Major facilitator Superfamily
J4774_RS15835	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
J4774_RS15840	COG2323	membrane
J4774_RS15855	COG0420	3'-5' exonuclease activity
J4774_RS15860	COG0419	ATPase involved in DNA repair
J4774_RS15865	COG1403	HNH endonuclease
J4774_RS15905	COG0179	Fumarylacetoacetate (FAA) hydrolase
J4774_RS15920	COG0367	asparagine synthase
J4774_RS15925	COG1562	ergosterol biosynthetic process
J4774_RS15930	COG0534	Mate efflux family protein
J4774_RS15935	COG1917	Cupin 2, conserved barrel domain protein
J4774_RS15935	COG2207	Transcriptional regulator
J4774_RS15940	COG1609	Transcriptional regulator
J4774_RS15945	COG0673	inositol 2-dehydrogenase activity
J4774_RS15950	COG2318	DinB family
J4774_RS15955	COG1357	PFAM Pentapeptide repeats (8 copies)
J4774_RS15960	COG2153	protein acetylation
J4774_RS15965	COG0646	methionine synthase
J4774_RS15965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J4774_RS15975	COG2996	Protein conserved in bacteria
J4774_RS15980	COG1744	ABC transporter substrate-binding protein PnrA-like
J4774_RS15985	COG0840	transmembrane signaling receptor activity
J4774_RS15995	COG1307	EDD domain protein, DegV family
J4774_RS16000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4774_RS16020	COG0561	phosphatase activity
J4774_RS16025	COG1073	alpha beta
J4774_RS16030	COG2151	metal-sulfur cluster biosynthetic enzyme
J4774_RS16040	COG0277	FAD linked oxidase domain protein
J4774_RS16045	COG2271	Major facilitator Superfamily
J4774_RS16055	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J4774_RS16065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4774_RS16070	COG0505	Belongs to the CarA family
J4774_RS16075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J4774_RS16080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J4774_RS16095	COG2267	carboxylic ester hydrolase activity
J4774_RS16105	COG1744	ABC transporter substrate-binding protein PnrA-like
J4774_RS16120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4774_RS16125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4774_RS16130	COG5504	Zn-dependent protease
J4774_RS16135	COG0444	Belongs to the ABC transporter superfamily
J4774_RS16140	COG4608	Belongs to the ABC transporter superfamily
J4774_RS16150	COG0601	transmembrane transport
J4774_RS16155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4774_RS16165	COG0180	Tryptophanyl-tRNA synthetase
J4774_RS16170	COG4166	transmembrane transport
J4774_RS16175	COG0601	transmembrane transport
J4774_RS16180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4774_RS16185	COG0444	Belongs to the ABC transporter superfamily
J4774_RS16190	COG4608	Belongs to the ABC transporter superfamily
J4774_RS16200	COG0456	acetyltransferase
J4774_RS16205	COG1393	Belongs to the ArsC family
J4774_RS16210	COG0861	Integral membrane protein TerC family
J4774_RS16220	COG4862	establishment of competence for transformation
J4774_RS16225	COG4469	Competence protein
J4774_RS16230	COG1164	Oligoendopeptidase f
J4774_RS16240	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J4774_RS16245	COG2346	COG2346, Truncated hemoglobins
J4774_RS16250	COG0741	lytic transglycosylase activity
J4774_RS16255	COG4116	CYTH
J4774_RS16265	COG2357	RelA SpoT domain protein
J4774_RS16270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J4774_RS16275	COG0564	pseudouridine synthase activity
J4774_RS16285	COG0475	glutathione-regulated potassium exporter activity
J4774_RS16285	COG0569	domain protein
J4774_RS16290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J4774_RS16295	COG0352	thiamine-phosphate diphosphorylase activity
J4774_RS16300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4774_RS16305	COG2104	thiamine diphosphate biosynthetic process
J4774_RS16315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4774_RS16320	COG0351	phosphomethylpyrimidine kinase
J4774_RS16325	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4774_RS16380	COG0210	DNA helicase
J4774_RS16400	COG1131	(ABC) transporter
J4774_RS16410	COG2153	protein acetylation
J4774_RS16420	COG2382	esterase
J4774_RS16425	COG0626	cystathionine gamma-synthase activity
J4774_RS16430	COG0626	cystathionine gamma-synthase activity
J4774_RS16475	COG1279	arginine transmembrane transporter activity
J4774_RS16515	COG0135	phosphoribosylanthranilate isomerase activity
J4774_RS16525	COG0346	lactoylglutathione lyase activity
J4774_RS16530	COG2367	Beta-lactamase
J4774_RS16535	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J4774_RS16540	COG0477	Major facilitator Superfamily
J4774_RS16545	COG1846	Transcriptional regulator
J4774_RS16555	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
J4774_RS16560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4774_RS16565	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J4774_RS16570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4774_RS16570	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4774_RS16575	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4774_RS16585	COG1349	DNA-binding transcription factor activity
J4774_RS16600	COG1285	pathogenesis
J4774_RS16610	COG2205	protein histidine kinase activity
J4774_RS16620	COG3383	formate dehydrogenase (NAD+) activity
J4774_RS16625	COG2427	Protein of unknown function (DUF1641)
J4774_RS16630	COG2124	cytochrome p450
J4774_RS16635	COG1819	glycosyl
J4774_RS16645	COG1587	Uroporphyrinogen-III synthase
J4774_RS16650	COG0390	transport system, permease component
J4774_RS16655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4774_RS16660	COG0697	spore germination
J4774_RS16665	COG4297	protein containing double-stranded beta helix domain
J4774_RS16675	COG1252	NADH dehydrogenase
J4774_RS16685	COG2211	Major facilitator Superfamily
J4774_RS16690	COG1609	Transcriptional regulator
J4774_RS16695	COG2721	sulfolactate sulfo-lyase activity
J4774_RS16700	COG0745	RESPONSE REGULATOR receiver
J4774_RS16705	COG2770	Histidine kinase
J4774_RS16705	COG2205	protein histidine kinase activity
J4774_RS16725	COG4585	Histidine kinase
J4774_RS16730	COG2197	response regulator
J4774_RS16765	COG0730	response to heat
J4774_RS16770	COG2318	DinB family
J4774_RS16775	COG0457	Tetratricopeptide repeat
J4774_RS16785	COG1388	LysM domain
J4774_RS16785	COG3409	Peptidoglycan-binding domain 1 protein
J4774_RS16785	COG5632	N-Acetylmuramoyl-L-alanine amidase
J4774_RS16795	COG4195	phage-related replication protein
J4774_RS16805	COG2856	Zn peptidase
J4774_RS16810	COG1396	sequence-specific DNA binding
J4774_RS16820	COG1522	sequence-specific DNA binding
J4774_RS16825	COG1484	DNA-dependent DNA replication
J4774_RS16845	COG1595	DNA-templated transcription, initiation
J4774_RS16850	COG3728	DNA packaging
J4774_RS16850	COG5484	DNA packaging
J4774_RS16855	COG1783	phage Terminase large subunit
J4774_RS16860	COG5518	Phage portal protein
J4774_RS16865	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J4774_RS16870	COG4653	Phage capsid family
J4774_RS16920	COG3953	SLT domain
J4774_RS16920	COG5412	phage tail tape measure protein
J4774_RS16920	COG3953	SLT domain
J4774_RS16920	COG5412	phage tail tape measure protein
J4774_RS16920	COG5412	phage tail tape measure protein
J4774_RS16920	COG3953	SLT domain
J4774_RS16925	COG1652	LysM domain
J4774_RS16930	COG4193	domain, Protein
J4774_RS16940	COG3628	GPW Gp25 family protein
J4774_RS16945	COG3299	homolog of phage Mu protein gp47
J4774_RS16950	COG3778	Protein conserved in bacteria
J4774_RS16990	COG5632	N-Acetylmuramoyl-L-alanine amidase
J4774_RS16990	COG3409	Peptidoglycan-binding domain 1 protein
J4774_RS17005	COG0306	phosphate transporter
J4774_RS17010	COG1392	Phosphate transport regulator
J4774_RS17015	COG0531	amino acid
J4774_RS17020	COG0346	lactoylglutathione lyase activity
J4774_RS17025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J4774_RS17030	COG0463	Glycosyl transferase, family 2
J4774_RS17040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4774_RS17045	COG0477	Major facilitator Superfamily
J4774_RS17050	COG2362	D-Aminopeptidase
J4774_RS17055	COG0601	transmembrane transport
J4774_RS17060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4774_RS17065	COG0444	Belongs to the ABC transporter superfamily
J4774_RS17070	COG4166	transmembrane transport
J4774_RS17075	COG1619	proteins homologs of microcin C7 resistance protein MccF
J4774_RS17080	COG4948	Mandelate Racemase Muconate Lactonizing
J4774_RS17085	COG0791	NLP P60 protein
J4774_RS17090	COG4608	Belongs to the ABC transporter superfamily
J4774_RS17095	COG2706	6-phosphogluconolactonase activity
J4774_RS17100	COG1834	amidinotransferase
J4774_RS17105	COG1607	acyl-coa hydrolase
J4774_RS17110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4774_RS17115	COG2076	Multidrug Resistance protein
J4774_RS17120	COG2076	Multidrug Resistance protein
J4774_RS17125	COG0788	formyltetrahydrofolate deformylase activity
J4774_RS17130	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J4774_RS17140	COG1764	response to oxidative stress
J4774_RS17145	COG1846	Transcriptional regulator
J4774_RS17150	COG1764	response to oxidative stress
J4774_RS17165	COG0463	Glycosyl transferase, family 2
J4774_RS17165	COG0457	Tetratricopeptide repeat
J4774_RS17175	COG2814	Major facilitator Superfamily
J4774_RS17180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4774_RS17190	COG1404	Belongs to the peptidase S8 family
J4774_RS17195	COG1366	Belongs to the anti-sigma-factor antagonist family
J4774_RS17200	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J4774_RS17205	COG1122	ATPase activity
J4774_RS17210	COG4721	ABC-type cobalt transport system, permease component
J4774_RS17215	COG1388	LysM domain
J4774_RS17215	COG3858	chitin binding
J4774_RS17225	COG2239	Acts as a magnesium transporter
J4774_RS17230	COG0789	Transcriptional regulator
J4774_RS17245	COG1846	Transcriptional regulator
J4774_RS17250	COG0726	polysaccharide deacetylase
J4774_RS17255	COG1793	dna ligase
J4774_RS17255	COG3285	dna ligase
J4774_RS17260	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
J4774_RS17265	COG0586	Pfam SNARE associated Golgi protein
J4774_RS17270	COG0861	Integral membrane protein TerC family
J4774_RS17275	COG1191	sigma factor activity
J4774_RS17300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4774_RS17305	COG2323	membrane
J4774_RS17315	COG3594	Acyltransferase
J4774_RS17320	COG5002	protein histidine kinase activity
J4774_RS17325	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J4774_RS17340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4774_RS17345	COG0436	Aminotransferase
J4774_RS17375	COG3852	Histidine kinase
J4774_RS17380	COG1846	Transcriptional regulator
J4774_RS17385	COG1360	Flagellar Motor Protein
J4774_RS17390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4774_RS17395	COG0542	response to heat
J4774_RS17400	COG3949	Membrane
J4774_RS17415	COG0720	synthase
J4774_RS17420	COG0602	queuosine metabolic process
J4774_RS17435	COG4873	Protein conserved in bacteria
J4774_RS17445	COG3773	Cell wall hydrolase
J4774_RS17450	COG2244	polysaccharide biosynthetic process
J4774_RS17455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4774_RS17460	COG2217	Heavy metal translocating P-type atpase
J4774_RS17465	COG0006	proline dipeptidase activity
J4774_RS17470	COG1609	Transcriptional regulator
J4774_RS17475	COG3711	transcriptional antiterminator
J4774_RS17480	COG1263	PTS System
J4774_RS17480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4774_RS17480	COG2190	(PTS) system
J4774_RS17485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4774_RS17490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4774_RS17500	COG1533	DNA photolyase activity
J4774_RS17505	COG0840	transmembrane signaling receptor activity
J4774_RS17510	COG2084	Dehydrogenase
J4774_RS17520	COG0347	Belongs to the P(II) protein family
J4774_RS17525	COG2340	Cysteine-rich secretory protein family
J4774_RS17530	COG0768	penicillin binding
J4774_RS17535	COG4191	Histidine kinase
J4774_RS17540	COG0436	Aminotransferase
J4774_RS17550	COG0784	Response regulator, receiver
J4774_RS17550	COG0835	chemotaxis
J4774_RS17560	COG2814	Major facilitator Superfamily
J4774_RS17565	COG1376	ErfK ybiS ycfS ynhG family protein
J4774_RS17570	COG1408	metallophosphoesterase
J4774_RS17575	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS17585	COG2200	EAL domain
J4774_RS17590	COG4703	Protein of unknown function (DUF1797)
J4774_RS17595	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
J4774_RS17605	COG0517	IMP dehydrogenase activity
J4774_RS17610	COG0583	DNA-binding transcription factor activity
J4774_RS17615	COG0716	FMN binding
J4774_RS17625	COG0716	FMN binding
J4774_RS17645	COG0668	transmembrane transport
J4774_RS17650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4774_RS17670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4774_RS17675	COG0303	'Molybdopterin
J4774_RS17680	COG1763	Mo-molybdopterin cofactor biosynthetic process
J4774_RS17685	COG0314	molybdopterin synthase activity
J4774_RS17690	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J4774_RS17700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4774_RS17705	COG1136	(ABC) transporter
J4774_RS17710	COG0577	efflux transmembrane transporter activity
J4774_RS17715	COG1349	DNA-binding transcription factor activity
J4774_RS17720	COG1105	Belongs to the carbohydrate kinase PfkB family
J4774_RS17725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4774_RS17725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4774_RS17725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4774_RS17730	COG0681	Belongs to the peptidase S26 family
J4774_RS17740	COG0488	(ABC) transporter
J4774_RS17745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J4774_RS17750	COG2309	aminopeptidase activity
J4774_RS17760	COG1077	Cell shape determining protein MreB Mrl
J4774_RS17765	COG2002	toxin-antitoxin pair type II binding
J4774_RS17770	COG3852	Histidine kinase
J4774_RS17775	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
J4774_RS17775	COG2105	PFAM AIG2 family protein
J4774_RS17780	COG0569	domain protein
J4774_RS17790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J4774_RS17800	COG0561	phosphatase activity
J4774_RS17805	COG0242	peptide deformylase activity
J4774_RS17815	COG0497	DNA recombination
J4774_RS17825	COG3321	synthase
J4774_RS17825	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS17825	COG4221	oxidoreductase activity
J4774_RS17825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS17830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4774_RS17830	COG0300	oxidoreductase activity
J4774_RS17830	COG3321	synthase
J4774_RS17830	COG4221	oxidoreductase activity
J4774_RS17835	COG4221	oxidoreductase activity
J4774_RS17835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS17835	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS17835	COG3321	synthase
J4774_RS17840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4774_RS17840	COG0300	oxidoreductase activity
J4774_RS17840	COG3321	synthase
J4774_RS17840	COG4221	oxidoreductase activity
J4774_RS17845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4774_RS17845	COG4221	oxidoreductase activity
J4774_RS17845	COG0300	oxidoreductase activity
J4774_RS17845	COG3321	synthase
J4774_RS17850	COG4221	oxidoreductase activity
J4774_RS17850	COG3321	synthase
J4774_RS17850	COG0300	oxidoreductase activity
J4774_RS17850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4774_RS17855	COG4221	oxidoreductase activity
J4774_RS17855	COG3321	synthase
J4774_RS17855	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS17855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS17860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J4774_RS17865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J4774_RS17870	COG0022	dehydrogenase e1 component
J4774_RS17875	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4774_RS17880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4774_RS17885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4774_RS17900	COG1982	Orn Lys Arg decarboxylase major
J4774_RS17920	COG0483	inositol monophosphate 1-phosphatase activity
J4774_RS17930	COG3227	Zinc metalloprotease (Elastase)
J4774_RS17955	COG1217	gtp-binding protein TYPA
J4774_RS17965	COG4896	Protein conserved in bacteria
J4774_RS17975	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J4774_RS17980	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J4774_RS17985	COG2066	Belongs to the glutaminase family
J4774_RS17995	COG0772	Belongs to the SEDS family
J4774_RS18000	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J4774_RS18015	COG2010	Cytochrome c
J4774_RS18015	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4774_RS18020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4774_RS18025	COG1845	cytochrome c oxidase, subunit III
J4774_RS18030	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J4774_RS18035	COG3336	cytochrome c oxidase
J4774_RS18045	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
J4774_RS18050	COG2340	Cysteine-rich secretory protein family
J4774_RS18065	COG3679	Belongs to the UPF0342 family
J4774_RS18080	COG0742	ribosomal rna small subunit methyltransferase
J4774_RS18090	COG3314	Sporulation integral membrane protein YlbJ
J4774_RS18095	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4774_RS18100	COG3480	Lon protease (S16) C-terminal proteolytic domain
J4774_RS18110	COG1399	metal-binding, possibly nucleic acid-binding protein
J4774_RS18130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J4774_RS18150	COG4839	cell division protein FtsL
J4774_RS18155	COG0768	penicillin binding
J4774_RS18160	COG0768	penicillin binding
J4774_RS18180	COG0772	Belongs to the SEDS family
J4774_RS18195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J4774_RS18200	COG0849	cell division
J4774_RS18205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J4774_RS18210	COG4412	M6 family metalloprotease domain protein
J4774_RS18210	COG1404	Belongs to the peptidase S8 family
J4774_RS18220	COG1191	sigma factor activity
J4774_RS18225	COG1191	sigma factor activity
J4774_RS18230	COG1119	ATPase activity
J4774_RS18235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4774_RS18240	COG1873	PFAM PRC-barrel domain
J4774_RS18245	COG1496	oxidoreductase activity
J4774_RS18250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J4774_RS18260	COG0762	integral membrane protein
J4774_RS18265	COG2302	S4 RNA-binding domain
J4774_RS18270	COG3599	regulation of cell shape
J4774_RS18275	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J4774_RS18280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4774_RS18290	COG0564	pseudouridine synthase activity
J4774_RS18300	COG2233	PERMEase
J4774_RS18310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4774_RS18315	COG0505	Belongs to the CarA family
J4774_RS18320	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J4774_RS18335	COG0284	orotidine-5'-phosphate decarboxylase activity
J4774_RS18340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J4774_RS18350	COG0306	phosphate transporter
J4774_RS18365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4774_RS18370	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
J4774_RS18375	COG1648	precorrin-2 dehydrogenase activity
J4774_RS18385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J4774_RS18390	COG1561	YicC-like family, N-terminal region
J4774_RS18400	COG0194	GDP metabolic process
J4774_RS18410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J4774_RS18415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4774_RS18420	COG0242	peptide deformylase activity
J4774_RS18430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4774_RS18430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4774_RS18440	COG0631	protein serine/threonine phosphatase activity
J4774_RS18445	COG2815	serine threonine protein kinase
J4774_RS18445	COG0515	serine threonine protein kinase
J4774_RS18455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J4774_RS18460	COG1564	THIamine pyrophosphokinase
J4774_RS18475	COG1302	Protein conserved in bacteria
J4774_RS18480	COG1461	Dihydroxyacetone kinase
J4774_RS18485	COG1760	l-serine dehydratase
J4774_RS18490	COG1760	l-serine dehydratase
J4774_RS18495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4774_RS18510	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J4774_RS18515	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS18530	COG1196	nuclear chromosome segregation
J4774_RS18535	COG0552	protein localization to endoplasmic reticulum
J4774_RS18550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J4774_RS18560	COG1837	Belongs to the UPF0109 family
J4774_RS18585	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4774_RS18600	COG2257	FlhB HrpN YscU SpaS Family
J4774_RS18610	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J4774_RS18615	COG0758	DNA mediated transformation
J4774_RS18620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4774_RS18630	COG4974	Belongs to the 'phage' integrase family
J4774_RS18650	COG1815	bacterial-type flagellum-dependent cell motility
J4774_RS18655	COG1558	bacterial-type flagellum-dependent cell motility
J4774_RS18660	COG1677	Flagellar hook-basal body complex protein FliE
J4774_RS18665	COG1766	The M ring may be actively involved in energy transduction
J4774_RS18670	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4774_RS18675	COG1317	bacterial-type flagellum organization
J4774_RS18680	COG1157	protein secretion by the type III secretion system
J4774_RS18685	COG2882	bacterial-type flagellum organization
J4774_RS18690	COG3334	PFAM MgtE intracellular
J4774_RS18695	COG3144	bacterial-type flagellum assembly
J4774_RS18700	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J4774_RS18705	COG4786	Flagellar basal body rod
J4774_RS18710	COG1582	Flagellar protein (FlbD)
J4774_RS18715	COG1580	Controls the rotational direction of flagella during chemotaxis
J4774_RS18720	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4774_RS18725	COG1776	CheC inhibitor of MCP methylation
J4774_RS18725	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4774_RS18730	COG2201	protein-glutamate methylesterase activity
J4774_RS18735	COG3190	flagellar
J4774_RS18740	COG1338	Plays a role in the flagellum-specific transport system
J4774_RS18745	COG1987	bacterial-type flagellum assembly
J4774_RS18750	COG1684	flagellar biosynthetic protein fliR
J4774_RS18755	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J4774_RS18760	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J4774_RS18765	COG1419	protein localization to endoplasmic reticulum
J4774_RS18770	COG0455	bacterial-type flagellum organization
J4774_RS18775	COG2201	protein-glutamate methylesterase activity
J4774_RS18780	COG0643	Histidine kinase
J4774_RS18780	COG2198	Histidine kinase
J4774_RS18785	COG0835	chemotaxis
J4774_RS18790	COG1776	CheC inhibitor of MCP methylation
J4774_RS18800	COG1191	sigma factor activity
J4774_RS18830	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4774_RS18835	COG4589	Belongs to the CDS family
J4774_RS18845	COG0750	zinc metalloprotease
J4774_RS18855	COG2176	DNA-directed DNA polymerase activity
J4774_RS18865	COG0195	Participates in both transcription termination and antitermination
J4774_RS18870	COG2740	Nucleic-acid-binding protein implicated in transcription termination
J4774_RS18875	COG1358	cellular component organization or biogenesis
J4774_RS18885	COG1550	Protein conserved in bacteria
J4774_RS18900	COG0196	riboflavin kinase activity
J4774_RS18915	COG0726	polysaccharide deacetylase
J4774_RS18920	COG0612	Peptidase, M16
J4774_RS18925	COG1873	PFAM PRC-barrel domain
J4774_RS18930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4774_RS18935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J4774_RS18940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4774_RS18945	COG0527	aspartate kinase activity
J4774_RS18955	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J4774_RS18960	COG0740	serine-type endopeptidase activity
J4774_RS18970	COG4980	gas vesicle protein
J4774_RS18970	COG1674	ftsk spoiiie
J4774_RS18975	COG2188	Transcriptional regulator
J4774_RS18980	COG2814	Major facilitator Superfamily
J4774_RS18985	COG1846	Transcriptional regulator
J4774_RS18990	COG2409	Drug exporters of the RND superfamily
J4774_RS18990	COG1033	growth of symbiont in host cell
J4774_RS18995	COG0612	Peptidase, M16
J4774_RS19000	COG0612	Peptidase, M16
J4774_RS19005	COG0300	oxidoreductase activity
J4774_RS19020	COG1426	Protein conserved in bacteria
J4774_RS19025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J4774_RS19040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J4774_RS19050	COG1692	metallophosphoesterase
J4774_RS19055	COG2359	stage V sporulation protein S
J4774_RS19075	COG4550	Control of competence regulator ComK, YlbF/YmcA
J4774_RS19120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4774_RS19125	COG3425	synthase
J4774_RS19130	COG1024	Enoyl-CoA hydratase
J4774_RS19135	COG1024	Enoyl-CoA hydratase
J4774_RS19140	COG3321	synthase
J4774_RS19140	COG1028	Short-chain dehydrogenase reductase Sdr
J4774_RS19140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4774_RS19140	COG0318	PFAM AMP-dependent synthetase and ligase
J4774_RS19140	COG0300	oxidoreductase activity
J4774_RS19145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4774_RS19145	COG0300	oxidoreductase activity
J4774_RS19145	COG4221	oxidoreductase activity
J4774_RS19145	COG3321	synthase