locus-tag	class	description
D073_RS00010	COG0592	DNA-directed DNA polymerase activity
D073_RS00015	COG2501	S4 domain
D073_RS00030	COG0187	DNA topoisomerase II activity
D073_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D073_RS00060	COG0517	IMP dehydrogenase activity
D073_RS00060	COG0516	GMP reductase activity
D073_RS00065	COG1686	Belongs to the peptidase S11 family
D073_RS00085	COG1929	Belongs to the glycerate kinase type-1 family
D073_RS00095	COG1428	Deoxynucleoside kinase
D073_RS00100	COG1428	Deoxynucleoside kinase
D073_RS00105	COG3858	chitin binding
D073_RS00105	COG1388	LysM domain
D073_RS00110	COG1335	isochorismatase
D073_RS00115	COG0590	tRNA wobble adenosine to inosine editing
D073_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D073_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D073_RS00170	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D073_RS00175	COG3853	Toxic anion resistance protein (TelA)
D073_RS00180	COG1982	Orn Lys Arg decarboxylase major
D073_RS00190	COG3870	Protein conserved in bacteria
D073_RS00195	COG1728	Protein conserved in bacteria
D073_RS00200	COG0470	DNA polymerase III
D073_RS00205	COG1774	PSP1 C-terminal conserved region
D073_RS00215	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D073_RS00225	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D073_RS00230	COG2002	toxin-antitoxin pair type II binding
D073_RS00235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D073_RS00235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D073_RS00240	COG0084	hydrolase, TatD family'
D073_RS00245	COG3584	3D domain protein
D073_RS00245	COG3583	domain protein
D073_RS00250	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D073_RS00255	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D073_RS00265	COG4466	Protein conserved in bacteria
D073_RS00280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D073_RS00285	COG0251	oxidation-reduction process
D073_RS00300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D073_RS00320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D073_RS00325	COG2002	toxin-antitoxin pair type II binding
D073_RS00330	COG2244	polysaccharide biosynthetic process
D073_RS00335	COG3956	TIGRFAM MazG family protein
D073_RS00340	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D073_RS00355	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D073_RS00360	COG1098	S1 RNA binding domain
D073_RS00375	COG2208	phosphoserine phosphatase activity
D073_RS00380	COG2304	oxidoreductase activity
D073_RS00385	COG0515	serine threonine protein kinase
D073_RS00390	COG0037	tRNA processing
D073_RS00395	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D073_RS00400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D073_RS00415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D073_RS00420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D073_RS00425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D073_RS00430	COG0512	Glutamine amidotransferase of anthranilate synthase
D073_RS00435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D073_RS00440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D073_RS00445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D073_RS00450	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D073_RS00455	COG1396	sequence-specific DNA binding
D073_RS00460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D073_RS00465	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D073_RS00545	COG4463	regulation of RNA biosynthetic process
D073_RS00550	COG3880	PFAM UvrB UvrC protein
D073_RS00560	COG0542	response to heat
D073_RS00565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D073_RS00570	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D073_RS00575	COG4956	integral membrane protein (PIN domain superfamily)
D073_RS00595	COG1045	serine acetyltransferase
D073_RS00605	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D073_RS00610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D073_RS00615	COG3688	RNA-binding protein containing a PIN domain
D073_RS00620	COG1595	DNA-templated transcription, initiation
D073_RS00630	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D073_RS00635	COG0250	Participates in transcription elongation, termination and antitermination
D073_RS00660	COG2813	Specifically methylates the guanine in position
D073_RS00675	COG1358	cellular component organization or biogenesis
D073_RS00700	COG0596	Alpha beta hydrolase
D073_RS00810	COG0201	protein transport
D073_RS00820	COG0024	Methionine aminopeptidase
D073_RS00835	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D073_RS00860	COG1122	ATPase activity
D073_RS00865	COG1122	ATPase activity
D073_RS00870	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D073_RS00890	COG2226	methyltransferase
D073_RS00895	COG2318	DinB family
D073_RS00905	COG0860	N-Acetylmuramoyl-L-alanine amidase
D073_RS00910	COG0489	protein tyrosine kinase activity
D073_RS00920	COG2194	sulfuric ester hydrolase activity
D073_RS00925	COG0726	polysaccharide deacetylase
D073_RS01010	COG0738	Major facilitator superfamily
D073_RS01015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D073_RS01030	COG0659	secondary active sulfate transmembrane transporter activity
D073_RS01035	COG0385	Bile acid
D073_RS01040	COG2819	hydrolase of the alpha beta superfamily
D073_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D073_RS01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D073_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D073_RS01060	COG2207	Transcriptional regulator
D073_RS01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D073_RS01065	COG3876	Protein conserved in bacteria
D073_RS01070	COG1472	Belongs to the glycosyl hydrolase 3 family
D073_RS01075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D073_RS01080	COG1263	PTS System
D073_RS01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D073_RS01090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D073_RS01095	COG1683	Conserved Protein
D073_RS01125	COG1595	DNA-templated transcription, initiation
D073_RS01130	COG5662	AntiSigma factor
D073_RS01135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D073_RS01140	COG4856	YbbR-like protein
D073_RS01165	COG0515	serine threonine protein kinase
D073_RS01170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D073_RS01180	COG1346	cytolysis
D073_RS01185	COG1380	Effector of murein hydrolase LrgA
D073_RS01190	COG1846	Transcriptional regulator
D073_RS01195	COG1113	amino acid transport
D073_RS01200	COG1011	Hydrolase
D073_RS01205	COG4585	Histidine kinase
D073_RS01210	COG2197	response regulator
D073_RS01215	COG1131	(ABC) transporter
D073_RS01255	COG0531	amino acid
D073_RS01260	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D073_RS01275	COG0584	glycerophosphoryl diester phosphodiesterase
D073_RS01280	COG2271	Major facilitator Superfamily
D073_RS01295	COG2368	4-hydroxyphenylacetate
D073_RS01305	COG3409	Peptidoglycan-binding domain 1 protein
D073_RS01320	COG0371	Dehydrogenase
D073_RS01330	COG1183	phosphatidylcholine synthase activity
D073_RS01335	COG0586	Pfam SNARE associated Golgi protein
D073_RS01340	COG0688	phosphatidylethanolamine metabolic process
D073_RS01355	COG1301	dicarboxylic acid transport
D073_RS01360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D073_RS01365	COG0833	amino acid
D073_RS01370	COG2040	homocysteine
D073_RS01375	COG1115	amino acid carrier protein
D073_RS01380	COG2066	Belongs to the glutaminase family
D073_RS01385	COG4191	Histidine kinase
D073_RS01390	COG0784	Response regulator, receiver
D073_RS01405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D073_RS01410	COG0778	Nitroreductase
D073_RS01415	COG0346	lactoylglutathione lyase activity
D073_RS01420	COG2259	Doxx family
D073_RS01425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D073_RS01440	COG3773	Cell wall hydrolase
D073_RS01450	COG3540	Alkaline phosphatase
D073_RS01455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D073_RS01460	COG0805	protein transport
D073_RS01470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D073_RS01475	COG0477	Major facilitator Superfamily
D073_RS01480	COG1309	transcriptional regulator
D073_RS01485	COG0252	asparaginase activity
D073_RS01490	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D073_RS01495	COG3012	SEC-C Motif Domain Protein
D073_RS01495	COG1405	negative regulation of cell septum assembly
D073_RS01500	COG0667	Aldo Keto reductase
D073_RS01510	COG1595	DNA-templated transcription, initiation
D073_RS01515	COG1595	DNA-templated transcription, initiation
D073_RS01520	COG1876	peptidase activity
D073_RS01525	COG0457	Tetratricopeptide repeat
D073_RS01530	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS01535	COG0366	Alpha amylase catalytic
D073_RS01540	COG0803	Belongs to the bacterial solute-binding protein 9 family
D073_RS01545	COG1121	(ABC) transporter
D073_RS01550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D073_RS01555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D073_RS01560	COG2310	stress, protein
D073_RS01565	COG2310	stress, protein
D073_RS01570	COG2310	stress, protein
D073_RS01575	COG0861	Integral membrane protein TerC family
D073_RS01585	COG3853	Toxic anion resistance protein (TelA)
D073_RS01590	COG0477	Major facilitator Superfamily
D073_RS01595	COG4175	Glycine betaine
D073_RS01595	COG0517	IMP dehydrogenase activity
D073_RS01600	COG4176	ABC-type proline glycine betaine transport system permease component
D073_RS01605	COG2113	Glycine betaine
D073_RS01610	COG1473	amidohydrolase
D073_RS01615	COG1288	antiporter activity
D073_RS01625	COG0366	Alpha amylase catalytic
D073_RS01635	COG2814	Major facilitator Superfamily
D073_RS01640	COG1846	Transcriptional regulator
D073_RS01645	COG1280	lysine exporter protein (LysE YggA)
D073_RS01650	COG3403	YqcI/YcgG family
D073_RS01655	COG1113	amino acid transport
D073_RS01660	COG3665	Urea carboxylase-associated protein
D073_RS01675	COG1082	Xylose isomerase domain protein TIM barrel
D073_RS01680	COG2271	Major facilitator Superfamily
D073_RS01685	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D073_RS01695	COG3458	cephalosporin-C deacetylase activity
D073_RS01700	COG3541	Predicted nucleotidyltransferase
D073_RS01705	COG0506	proline dehydrogenase activity
D073_RS01710	COG1012	belongs to the aldehyde dehydrogenase family
D073_RS01720	COG2508	Transcriptional regulator
D073_RS01730	COG1587	Uroporphyrinogen-III synthase
D073_RS01730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D073_RS01735	COG2146	nitrite reductase [NAD(P)H] activity
D073_RS01740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D073_RS01745	COG0243	molybdopterin cofactor binding
D073_RS01750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D073_RS01755	COG2223	nitrite transmembrane transporter activity
D073_RS01760	COG0523	cobalamin synthesis protein
D073_RS01765	COG1063	alcohol dehydrogenase
D073_RS01770	COG1714	RDD family
D073_RS01780	COG2723	6-phospho-beta-galactosidase activity
D073_RS01790	COG3209	COG3209 Rhs family protein
D073_RS01795	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D073_RS01800	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D073_RS01805	COG1733	regulation of RNA biosynthetic process
D073_RS01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS01815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS01820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS01825	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D073_RS01840	COG0697	spore germination
D073_RS01845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D073_RS01855	COG2364	Membrane
D073_RS01860	COG1126	abc transporter atp-binding protein
D073_RS01865	COG0765	amino acid transport
D073_RS01870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D073_RS01875	COG0583	DNA-binding transcription factor activity
D073_RS01880	COG0163	prenyltransferase activity
D073_RS01885	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D073_RS01900	COG3104	oligopeptide transport
D073_RS01905	COG5434	Belongs to the glycosyl hydrolase 28 family
D073_RS01915	COG0697	spore germination
D073_RS01925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D073_RS01930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D073_RS01935	COG0456	acetyltransferase
D073_RS01940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D073_RS01945	COG0765	amino acid transport
D073_RS01950	COG1126	abc transporter atp-binding protein
D073_RS01955	COG1473	amidohydrolase
D073_RS01960	COG2079	MmgE PrpD family protein
D073_RS01965	COG1136	(ABC) transporter
D073_RS01970	COG0577	efflux transmembrane transporter activity
D073_RS01975	COG0745	RESPONSE REGULATOR receiver
D073_RS01980	COG5002	protein histidine kinase activity
D073_RS01980	COG3850	Histidine kinase
D073_RS01985	COG0457	Tetratricopeptide repeat
D073_RS02000	COG0527	aspartate kinase activity
D073_RS02005	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D073_RS02010	COG4605	iron ion homeostasis
D073_RS02015	COG4604	ABC transporter, ATP-binding protein
D073_RS02020	COG4607	ABC-type enterochelin transport system periplasmic component
D073_RS02025	COG2814	Major facilitator Superfamily
D073_RS02030	COG1309	transcriptional regulator
D073_RS02035	COG0778	Nitroreductase
D073_RS02040	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D073_RS02045	COG0640	Transcriptional regulator
D073_RS02050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D073_RS02055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D073_RS02060	COG1012	belongs to the aldehyde dehydrogenase family
D073_RS02065	COG4975	Glucose uptake
D073_RS02070	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS02075	COG4549	nuclear export factor GLE1
D073_RS02080	COG1276	copper resistance
D073_RS02080	COG2372	response to copper ion
D073_RS02085	COG1349	DNA-binding transcription factor activity
D073_RS02095	COG2213	PTS system mannitol-specific
D073_RS02100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D073_RS02110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D073_RS02120	COG0561	phosphatase activity
D073_RS02130	COG1914	H( )-stimulated, divalent metal cation uptake system
D073_RS02140	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D073_RS02145	COG1984	allophanate hydrolase subunit 2
D073_RS02150	COG1414	Transcriptional regulator
D073_RS02155	COG2755	lipolytic protein G-D-S-L family
D073_RS02165	COG2329	Antibiotic biosynthesis monooxygenase
D073_RS02170	COG0768	penicillin binding
D073_RS02175	COG4989	oxidoreductase activity
D073_RS02180	COG3711	transcriptional antiterminator
D073_RS02185	COG0318	PFAM AMP-dependent synthetase and ligase
D073_RS02190	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS02195	COG1917	Cupin 2, conserved barrel domain protein
D073_RS02200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D073_RS02205	COG3871	stress protein (general stress protein 26)
D073_RS02215	COG2814	Major facilitator Superfamily
D073_RS02220	COG1522	sequence-specific DNA binding
D073_RS02225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D073_RS02225	COG0551	DNA topoisomerase type I activity
D073_RS02230	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D073_RS02235	COG3706	GGDEF domain
D073_RS02240	COG5298	Protein conserved in bacteria
D073_RS02245	COG1215	transferase activity, transferring glycosyl groups
D073_RS02255	COG0531	amino acid
D073_RS02260	COG0494	nUDIX hydrolase
D073_RS02265	COG0028	Belongs to the TPP enzyme family
D073_RS02295	COG1794	racemase activity, acting on amino acids and derivatives
D073_RS02330	COG1914	H( )-stimulated, divalent metal cation uptake system
D073_RS02345	COG4876	unkown
D073_RS02355	COG2076	Multidrug Resistance protein
D073_RS02360	COG2217	Heavy metal translocating P-type atpase
D073_RS02365	COG3729	General stress protein
D073_RS02370	COG0662	Cupin 2, conserved barrel domain protein
D073_RS02375	COG2329	Antibiotic biosynthesis monooxygenase
D073_RS02380	COG3546	catalase activity
D073_RS02385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D073_RS02390	COG3290	protein histidine kinase activity
D073_RS02395	COG4565	transcriptional regulatory protein
D073_RS02400	COG1301	dicarboxylic acid transport
D073_RS02405	COG0628	permease
D073_RS02410	COG1131	(ABC) transporter
D073_RS02415	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D073_RS02425	COG1960	acyl-CoA dehydrogenase activity
D073_RS02440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D073_RS02445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D073_RS02455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D073_RS02460	COG0513	Belongs to the DEAD box helicase family
D073_RS02465	COG3402	PFAM membrane-flanked domain
D073_RS02470	COG3428	Bacterial PH domain
D073_RS02475	COG0705	Rhomboid family
D073_RS02485	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D073_RS02490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D073_RS02495	COG0864	Transcriptional regulator
D073_RS02500	COG2337	Toxic component of a toxin-antitoxin (TA) module
D073_RS02505	COG1366	Belongs to the anti-sigma-factor antagonist family
D073_RS02510	COG1366	Belongs to the anti-sigma-factor antagonist family
D073_RS02515	COG2172	sigma factor antagonist activity
D073_RS02520	COG2208	phosphoserine phosphatase activity
D073_RS02525	COG1366	Belongs to the anti-sigma-factor antagonist family
D073_RS02535	COG1191	sigma factor activity
D073_RS02540	COG2208	phosphoserine phosphatase activity
D073_RS02545	COG2183	response to ionizing radiation
D073_RS02610	COG1959	2 iron, 2 sulfur cluster binding
D073_RS02615	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D073_RS02620	COG1090	epimerase
D073_RS02635	COG1733	regulation of RNA biosynthetic process
D073_RS02640	COG2085	NADP oxidoreductase coenzyme F420-dependent
D073_RS02645	COG2249	NAD(P)H dehydrogenase (quinone) activity
D073_RS02660	COG0477	Major facilitator Superfamily
D073_RS02665	COG1846	Transcriptional regulator
D073_RS02675	COG2030	dehydratase
D073_RS02690	COG1959	2 iron, 2 sulfur cluster binding
D073_RS02695	COG2910	NAD(P)H-binding
D073_RS02705	COG1309	transcriptional regulator
D073_RS02710	COG0300	oxidoreductase activity
D073_RS02720	COG3239	Fatty acid desaturase
D073_RS02730	COG1278	Cold shock
D073_RS02735	COG1329	Transcriptional regulator
D073_RS02740	COG1794	racemase activity, acting on amino acids and derivatives
D073_RS02755	COG0456	acetyltransferase
D073_RS02755	COG1846	Transcriptional regulator
D073_RS02760	COG2271	Major facilitator Superfamily
D073_RS02765	COG3621	Patatin-like phospholipase
D073_RS02775	COG0662	Cupin 2, conserved barrel domain protein
D073_RS02790	COG0277	FAD linked oxidase domain protein
D073_RS02815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D073_RS02850	COG0351	phosphomethylpyrimidine kinase
D073_RS02865	COG1064	alcohol dehydrogenase
D073_RS02870	COG0789	Transcriptional regulator
D073_RS02880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D073_RS02895	COG2814	Major facilitator Superfamily
D073_RS02900	COG1309	transcriptional regulator
D073_RS02905	COG0697	spore germination
D073_RS02910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D073_RS02915	COG5577	PFAM Coat F domain
D073_RS02925	COG1063	alcohol dehydrogenase
D073_RS02930	COG5577	PFAM Coat F domain
D073_RS02945	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D073_RS02950	COG0488	(ABC) transporter
D073_RS02955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D073_RS02960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D073_RS02970	COG2814	Major facilitator Superfamily
D073_RS02975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D073_RS02985	COG0730	response to heat
D073_RS02990	COG0456	acetyltransferase
D073_RS02995	COG4978	Transcriptional regulator
D073_RS02995	COG0789	Transcriptional regulator
D073_RS03000	COG0697	spore germination
D073_RS03005	COG1051	belongs to the nudix hydrolase family
D073_RS03010	COG2226	methyltransferase
D073_RS03030	COG1802	Transcriptional regulator
D073_RS03035	COG1819	glycosyl
D073_RS03050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D073_RS03055	COG1388	LysM domain
D073_RS03060	COG2814	Major facilitator Superfamily
D073_RS03065	COG2188	Transcriptional regulator
D073_RS03070	COG2186	Transcriptional regulator
D073_RS03075	COG2807	transmembrane transport
D073_RS03080	COG2076	Multidrug Resistance protein
D073_RS03085	COG2076	Multidrug Resistance protein
D073_RS03090	COG1309	transcriptional regulator
D073_RS03095	COG0531	amino acid
D073_RS03105	COG3832	glyoxalase III activity
D073_RS03110	COG0604	alcohol dehydrogenase
D073_RS03115	COG2814	Major facilitator Superfamily
D073_RS03155	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D073_RS03160	COG0802	atpase or kinase
D073_RS03165	COG1214	PFAM Peptidase M22, glycoprotease
D073_RS03170	COG0456	acetyltransferase
D073_RS03175	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D073_RS03180	COG0488	(ABC) transporter
D073_RS03195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D073_RS03200	COG0805	protein transport
D073_RS03210	COG1266	CAAX protease self-immunity
D073_RS03230	COG5444	nuclease activity
D073_RS03250	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D073_RS03255	COG0457	Tetratricopeptide repeat
D073_RS03260	COG1063	alcohol dehydrogenase
D073_RS03265	COG2211	Major facilitator Superfamily
D073_RS03270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D073_RS03280	COG1842	Phage shock protein A
D073_RS03285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D073_RS03290	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D073_RS03295	COG4260	virion core protein, lumpy skin disease virus
D073_RS03300	COG2755	lipolytic protein G-D-S-L family
D073_RS03300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D073_RS03310	COG1595	DNA-templated transcription, initiation
D073_RS03315	COG1063	alcohol dehydrogenase
D073_RS03320	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D073_RS03325	COG0823	Involved in the tonB-independent uptake of proteins
D073_RS03335	COG2132	Multicopper oxidase
D073_RS03340	COG1113	amino acid transport
D073_RS03345	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D073_RS03350	COG0714	Associated with various cellular activities
D073_RS03355	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D073_RS03360	COG1305	Transglutaminase-like
D073_RS03385	COG2252	PERMEase
D073_RS03390	COG3064	Membrane
D073_RS03410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D073_RS03415	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D073_RS03420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D073_RS03425	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D073_RS03430	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D073_RS03445	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D073_RS03455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D073_RS03460	COG0138	bifunctional purine biosynthesis protein purh
D073_RS03465	COG0151	Belongs to the GarS family
D073_RS03475	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D073_RS03480	COG1470	cell adhesion involved in biofilm formation
D073_RS03485	COG4496	protein, YerC YecD
D073_RS03490	COG0069	glutamate synthase activity
D073_RS03500	COG0210	DNA helicase
D073_RS03510	COG4851	CamS sex pheromone cAM373 precursor
D073_RS03515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D073_RS03520	COG1285	pathogenesis
D073_RS03525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D073_RS03545	COG1309	transcriptional regulator
D073_RS03550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D073_RS03555	COG1597	lipid kinase activity
D073_RS03560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D073_RS03565	COG2197	response regulator
D073_RS03575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D073_RS03585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D073_RS03595	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS03600	COG1131	(ABC) transporter
D073_RS03635	COG5444	nuclease activity
D073_RS03665	COG3546	catalase activity
D073_RS03670	COG0454	-acetyltransferase
D073_RS03680	COG2323	membrane
D073_RS03685	COG2329	Antibiotic biosynthesis monooxygenase
D073_RS03690	COG0346	lactoylglutathione lyase activity
D073_RS03700	COG1366	Belongs to the anti-sigma-factor antagonist family
D073_RS03705	COG5583	Uncharacterized small protein (DUF2292)
D073_RS03710	COG0196	riboflavin kinase activity
D073_RS03715	COG0670	Belongs to the BI1 family
D073_RS03720	COG1846	Transcriptional regulator
D073_RS03725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D073_RS03735	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D073_RS03735	COG2124	cytochrome p450
D073_RS03740	COG1368	sulfuric ester hydrolase activity
D073_RS03745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D073_RS03750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D073_RS03755	COG1442	glycosyl transferase family 8
D073_RS03760	COG1216	Glycosyl transferase, family 2
D073_RS03765	COG1442	glycosyl transferase family 8
D073_RS03770	COG2223	nitrite transmembrane transporter activity
D073_RS03775	COG0531	amino acid
D073_RS03780	COG1012	belongs to the aldehyde dehydrogenase family
D073_RS03785	COG0840	transmembrane signaling receptor activity
D073_RS03790	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS03795	COG0463	Glycosyl transferase, family 2
D073_RS03795	COG0457	Tetratricopeptide repeat
D073_RS03800	COG0488	(ABC) transporter
D073_RS03805	COG0789	Transcriptional regulator
D073_RS03810	COG2814	Major facilitator Superfamily
D073_RS03815	COG0488	(ABC) transporter
D073_RS03820	COG0513	Belongs to the DEAD box helicase family
D073_RS03825	COG0456	acetyltransferase
D073_RS03830	COG2130	NADP-dependent
D073_RS03845	COG3866	Pectate lyase
D073_RS03850	COG0471	metal ion transport
D073_RS03875	COG3290	protein histidine kinase activity
D073_RS03880	COG4565	transcriptional regulatory protein
D073_RS03885	COG3181	Tripartite tricarboxylate transporter family receptor
D073_RS03890	COG2851	Citrate transporter
D073_RS03895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D073_RS03900	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D073_RS03910	COG2258	MOSC domain
D073_RS03930	COG0024	Methionine aminopeptidase
D073_RS03935	COG1263	PTS System
D073_RS03935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D073_RS03945	COG1368	sulfuric ester hydrolase activity
D073_RS03955	COG0071	Belongs to the small heat shock protein (HSP20) family
D073_RS03970	COG1263	PTS System
D073_RS03970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D073_RS03975	COG0366	Alpha amylase catalytic
D073_RS03980	COG2188	Transcriptional regulator
D073_RS03985	COG0778	Nitroreductase
D073_RS04000	COG0737	Belongs to the 5'-nucleotidase family
D073_RS04005	COG0693	protein deglycase activity
D073_RS04010	COG1609	Transcriptional regulator
D073_RS04030	COG2814	Major facilitator Superfamily
D073_RS04040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D073_RS04045	COG4980	gas vesicle protein
D073_RS04050	COG1295	ribonuclease BN
D073_RS04055	COG0477	Major facilitator Superfamily
D073_RS04060	COG0387	Pfam Sodium calcium exchanger
D073_RS04070	COG0668	transmembrane transport
D073_RS04075	COG0535	radical SAM domain protein
D073_RS04085	COG0726	polysaccharide deacetylase
D073_RS04090	COG2084	Dehydrogenase
D073_RS04100	COG0598	Magnesium transport protein CorA
D073_RS04105	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D073_RS04110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D073_RS04120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D073_RS04130	COG4637	Psort location Cytoplasmic, score
D073_RS04135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D073_RS04140	COG0022	dehydrogenase e1 component
D073_RS04145	COG0508	dehydrogenase complex catalyzes the overall conversion of
D073_RS04150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D073_RS04155	COG3284	Transcriptional regulator
D073_RS04165	COG1486	melibiose metabolic process
D073_RS04170	COG1737	Transcriptional regulator
D073_RS04175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D073_RS04175	COG1263	PTS System
D073_RS04180	COG1132	(ABC) transporter
D073_RS04185	COG1132	(ABC) transporter
D073_RS04190	COG2259	Doxx family
D073_RS04195	COG2514	catechol 2,3-dioxygenase activity
D073_RS04210	COG1695	Transcriptional regulator
D073_RS04215	COG2249	NAD(P)H dehydrogenase (quinone) activity
D073_RS04220	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D073_RS04225	COG3848	Pyruvate phosphate dikinase
D073_RS04225	COG0574	Belongs to the PEP-utilizing enzyme family
D073_RS04230	COG2732	(Barnase) inhibitor
D073_RS04235	COG2318	DinB family
D073_RS04240	COG2814	Major facilitator Superfamily
D073_RS04245	COG1846	Transcriptional regulator
D073_RS04250	COG0392	lysyltransferase activity
D073_RS04250	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D073_RS04255	COG0384	phenazine biosynthesis protein PhzF
D073_RS04260	COG0778	Nitroreductase
D073_RS04275	COG1090	epimerase
D073_RS04290	COG2814	Major facilitator Superfamily
D073_RS04300	COG3591	Belongs to the peptidase S1B family
D073_RS04315	COG3103	Sh3 type 3 domain protein
D073_RS04320	COG5658	integral membrane protein
D073_RS04325	COG0596	Alpha beta hydrolase
D073_RS04330	COG0463	Glycosyl transferase, family 2
D073_RS04335	COG4485	Bacterial membrane protein, YfhO
D073_RS04340	COG1988	membrane-bound metal-dependent
D073_RS04345	COG1194	a g-specific adenine glycosylase
D073_RS04355	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS04375	COG1132	(ABC) transporter
D073_RS04380	COG4129	membrane
D073_RS04390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D073_RS04395	COG0735	belongs to the Fur family
D073_RS04505	COG1757	Na H antiporter
D073_RS04510	COG3340	Belongs to the peptidase S51 family
D073_RS04520	COG0277	FAD linked oxidase domain protein
D073_RS04530	COG0747	negative chemotaxis
D073_RS04535	COG0601	transmembrane transport
D073_RS04540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D073_RS04545	COG0444	Belongs to the ABC transporter superfamily
D073_RS04550	COG4608	Belongs to the ABC transporter superfamily
D073_RS04555	COG0753	catalase activity
D073_RS04570	COG1116	anion transmembrane transporter activity
D073_RS04575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D073_RS04580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D073_RS04600	COG1476	TRANSCRIPTIONal
D073_RS04610	COG3382	B3 4 domain protein
D073_RS04615	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D073_RS04625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D073_RS04630	COG0789	Transcriptional regulator
D073_RS04635	COG1664	Polymer-forming cytoskeletal
D073_RS04640	COG1664	Polymer-forming cytoskeletal
D073_RS04645	COG2766	serine protein kinase
D073_RS04660	COG1846	Transcriptional regulator
D073_RS04665	COG1566	PFAM secretion protein HlyD family protein
D073_RS04670	COG2814	Major facilitator Superfamily
D073_RS04675	COG0655	NAD(P)H dehydrogenase (quinone) activity
D073_RS04690	COG1725	Transcriptional regulator
D073_RS04695	COG1131	(ABC) transporter
D073_RS04700	COG1131	(ABC) transporter
D073_RS04705	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D073_RS04710	COG1278	Cold shock
D073_RS04720	COG1464	Belongs to the NlpA lipoprotein family
D073_RS04725	COG3706	GGDEF domain
D073_RS04730	COG1823	symporter activity
D073_RS04750	COG5577	PFAM Coat F domain
D073_RS04755	COG1525	nuclease
D073_RS04755	COG4085	toxin activity
D073_RS04755	COG0737	Belongs to the 5'-nucleotidase family
D073_RS04760	COG3764	Sortase (surface protein transpeptidase)
D073_RS04765	COG0564	pseudouridine synthase activity
D073_RS04775	COG0517	IMP dehydrogenase activity
D073_RS04780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D073_RS04785	COG3153	acetyltransferase
D073_RS04785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D073_RS04790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D073_RS04795	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D073_RS04800	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D073_RS04810	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D073_RS04815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D073_RS04820	COG4585	Histidine kinase
D073_RS04820	COG2203	Gaf domain
D073_RS04825	COG2197	response regulator
D073_RS04830	COG0431	NADPH-dependent FMN reductase
D073_RS04845	COG1388	LysM domain
D073_RS04845	COG0791	NLP P60 protein
D073_RS04850	COG1959	2 iron, 2 sulfur cluster binding
D073_RS04855	COG0668	transmembrane transport
D073_RS04860	COG2719	SpoVR family
D073_RS04865	COG1785	Belongs to the alkaline phosphatase family
D073_RS04870	COG0791	NLP P60 protein
D073_RS04870	COG1388	LysM domain
D073_RS04875	COG0583	DNA-binding transcription factor activity
D073_RS04880	COG0372	Belongs to the citrate synthase family
D073_RS04885	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS04890	COG0531	amino acid
D073_RS04895	COG0733	neurotransmitter:sodium symporter activity
D073_RS04910	COG1595	DNA-templated transcription, initiation
D073_RS04915	COG0204	Acyl-transferase
D073_RS04920	COG1253	flavin adenine dinucleotide binding
D073_RS04925	COG0789	Transcriptional regulator
D073_RS04930	COG0436	Aminotransferase
D073_RS04935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D073_RS04940	COG1253	flavin adenine dinucleotide binding
D073_RS04945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D073_RS04950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D073_RS04955	COG0584	glycerophosphoryl diester phosphodiesterase
D073_RS04965	COG0668	transmembrane transport
D073_RS04970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D073_RS04975	COG0726	polysaccharide deacetylase
D073_RS04980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D073_RS04985	COG3226	Transcriptional regulator
D073_RS04995	COG0589	response to stress
D073_RS05000	COG1132	(ABC) transporter
D073_RS05005	COG1132	(ABC) transporter
D073_RS05010	COG0702	epimerase
D073_RS05030	COG0189	ligase activity
D073_RS05035	COG0189	ligase activity
D073_RS05050	COG4335	DNA alkylation repair
D073_RS05055	COG0561	phosphatase activity
D073_RS05060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D073_RS05070	COG0475	glutathione-regulated potassium exporter activity
D073_RS05075	COG0490	domain, Protein
D073_RS05085	COG1024	Enoyl-CoA hydratase
D073_RS05095	COG4152	abc transporter atp-binding protein
D073_RS05100	COG1668	transmembrane transport
D073_RS05105	COG0420	3'-5' exonuclease activity
D073_RS05110	COG4717	serine-type aminopeptidase activity
D073_RS05125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D073_RS05165	COG4980	gas vesicle protein
D073_RS05180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D073_RS05185	COG0537	adenosine 5'-monophosphoramidase activity
D073_RS05190	COG1131	(ABC) transporter
D073_RS05195	COG4473	ABC transporter
D073_RS05205	COG1473	amidohydrolase
D073_RS05210	COG3069	C4-dicarboxylate transmembrane transporter activity
D073_RS05215	COG2329	Antibiotic biosynthesis monooxygenase
D073_RS05220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D073_RS05230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D073_RS05235	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D073_RS05240	COG1309	transcriptional regulator
D073_RS05245	COG1511	domain protein
D073_RS05250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D073_RS05260	COG1363	Peptidase, m42
D073_RS05265	COG1301	dicarboxylic acid transport
D073_RS05275	COG1234	tRNA 3'-trailer cleavage
D073_RS05280	COG0095	Lipoate-protein ligase
D073_RS05285	COG0702	epimerase
D073_RS05290	COG0318	PFAM AMP-dependent synthetase and ligase
D073_RS05300	COG0501	Belongs to the peptidase M48B family
D073_RS05305	COG1404	Belongs to the peptidase S8 family
D073_RS05315	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D073_RS05320	COG0406	alpha-ribazole phosphatase activity
D073_RS05325	COG0183	Belongs to the thiolase family
D073_RS05330	COG0318	PFAM AMP-dependent synthetase and ligase
D073_RS05335	COG1268	BioY protein
D073_RS05340	COG0840	transmembrane signaling receptor activity
D073_RS05345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D073_RS05345	COG0723	plastoquinol--plastocyanin reductase activity
D073_RS05350	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS05360	COG4903	ComK protein
D073_RS05365	COG5646	InterPro IPR014922
D073_RS05370	COG5646	InterPro IPR014922
D073_RS05395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D073_RS05410	COG0398	Pfam SNARE associated Golgi protein
D073_RS05415	COG0681	Belongs to the peptidase S26 family
D073_RS05420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D073_RS05425	COG1846	Transcriptional regulator
D073_RS05430	COG3180	Ammonia monooxygenase
D073_RS05435	COG2814	Major facilitator Superfamily
D073_RS05445	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D073_RS05450	COG2323	membrane
D073_RS05465	COG0420	3'-5' exonuclease activity
D073_RS05470	COG0419	ATPase involved in DNA repair
D073_RS05475	COG1403	HNH endonuclease
D073_RS05515	COG0179	Fumarylacetoacetate (FAA) hydrolase
D073_RS05535	COG0367	asparagine synthase
D073_RS05540	COG1562	ergosterol biosynthetic process
D073_RS05545	COG0534	Mate efflux family protein
D073_RS05550	COG2207	Transcriptional regulator
D073_RS05550	COG1917	Cupin 2, conserved barrel domain protein
D073_RS05555	COG2318	DinB family
D073_RS05560	COG1279	arginine transmembrane transporter activity
D073_RS05565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D073_RS05570	COG1357	PFAM Pentapeptide repeats (8 copies)
D073_RS05575	COG2153	protein acetylation
D073_RS05580	COG0646	methionine synthase
D073_RS05580	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D073_RS05590	COG2996	Protein conserved in bacteria
D073_RS05595	COG1744	ABC transporter substrate-binding protein PnrA-like
D073_RS05600	COG0840	transmembrane signaling receptor activity
D073_RS05605	COG2124	cytochrome p450
D073_RS05615	COG1307	EDD domain protein, DegV family
D073_RS05620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D073_RS05635	COG0561	phosphatase activity
D073_RS05640	COG1073	alpha beta
D073_RS05645	COG2151	metal-sulfur cluster biosynthetic enzyme
D073_RS05655	COG0277	FAD linked oxidase domain protein
D073_RS05660	COG2271	Major facilitator Superfamily
D073_RS05670	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D073_RS05680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D073_RS05685	COG0505	Belongs to the CarA family
D073_RS05690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D073_RS05695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D073_RS05715	COG2267	carboxylic ester hydrolase activity
D073_RS05725	COG1744	ABC transporter substrate-binding protein PnrA-like
D073_RS05740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D073_RS05745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D073_RS05750	COG5504	Zn-dependent protease
D073_RS05755	COG0444	Belongs to the ABC transporter superfamily
D073_RS05760	COG4608	Belongs to the ABC transporter superfamily
D073_RS05770	COG0601	transmembrane transport
D073_RS05775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D073_RS05785	COG0180	Tryptophanyl-tRNA synthetase
D073_RS05790	COG4166	transmembrane transport
D073_RS05795	COG0601	transmembrane transport
D073_RS05800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D073_RS05805	COG0444	Belongs to the ABC transporter superfamily
D073_RS05810	COG4608	Belongs to the ABC transporter superfamily
D073_RS05820	COG0456	acetyltransferase
D073_RS05825	COG1393	Belongs to the ArsC family
D073_RS05830	COG0861	Integral membrane protein TerC family
D073_RS05835	COG4862	establishment of competence for transformation
D073_RS05840	COG4469	Competence protein
D073_RS05845	COG1164	Oligoendopeptidase f
D073_RS05850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D073_RS05855	COG2346	COG2346, Truncated hemoglobins
D073_RS05860	COG0741	lytic transglycosylase activity
D073_RS05865	COG4116	CYTH
D073_RS05875	COG2357	RelA SpoT domain protein
D073_RS05880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D073_RS05885	COG0564	pseudouridine synthase activity
D073_RS05895	COG0569	domain protein
D073_RS05895	COG0475	glutathione-regulated potassium exporter activity
D073_RS05900	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D073_RS05905	COG0352	thiamine-phosphate diphosphorylase activity
D073_RS05910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D073_RS05915	COG2104	thiamine diphosphate biosynthetic process
D073_RS05925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D073_RS05930	COG0351	phosphomethylpyrimidine kinase
D073_RS05935	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D073_RS05990	COG0210	DNA helicase
D073_RS06010	COG1131	(ABC) transporter
D073_RS06020	COG2153	protein acetylation
D073_RS06030	COG2382	esterase
D073_RS06035	COG0626	cystathionine gamma-synthase activity
D073_RS06040	COG0626	cystathionine gamma-synthase activity
D073_RS06055	COG5444	nuclease activity
D073_RS06085	COG2367	Beta-lactamase
D073_RS06090	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D073_RS06095	COG2814	Major facilitator Superfamily
D073_RS06100	COG1846	Transcriptional regulator
D073_RS06110	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D073_RS06115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D073_RS06120	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D073_RS06125	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D073_RS06125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D073_RS06130	COG1447	Phosphotransferase system cellobiose-specific component IIA
D073_RS06165	COG1285	pathogenesis
D073_RS06180	COG2205	protein histidine kinase activity
D073_RS06190	COG3383	formate dehydrogenase (NAD+) activity
D073_RS06195	COG2427	Protein of unknown function (DUF1641)
D073_RS06200	COG2124	cytochrome p450
D073_RS06205	COG1819	glycosyl
D073_RS06215	COG1587	Uroporphyrinogen-III synthase
D073_RS06220	COG0390	transport system, permease component
D073_RS06225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D073_RS06230	COG0697	spore germination
D073_RS06235	COG4297	protein containing double-stranded beta helix domain
D073_RS06245	COG1252	NADH dehydrogenase
D073_RS06255	COG2211	Major facilitator Superfamily
D073_RS06260	COG1609	Transcriptional regulator
D073_RS06265	COG0246	Mannitol dehydrogenase
D073_RS06270	COG2721	sulfolactate sulfo-lyase activity
D073_RS06275	COG0730	response to heat
D073_RS06280	COG2318	DinB family
D073_RS06285	COG0457	Tetratricopeptide repeat
D073_RS06295	COG1388	LysM domain
D073_RS06295	COG3409	Peptidoglycan-binding domain 1 protein
D073_RS06295	COG5632	N-Acetylmuramoyl-L-alanine amidase
D073_RS06305	COG4195	phage-related replication protein
D073_RS06310	COG2856	Zn peptidase
D073_RS06315	COG1396	sequence-specific DNA binding
D073_RS06325	COG1522	sequence-specific DNA binding
D073_RS06330	COG1484	DNA-dependent DNA replication
D073_RS06345	COG1595	DNA-templated transcription, initiation
D073_RS06350	COG3728	DNA packaging
D073_RS06350	COG5484	DNA packaging
D073_RS06355	COG1783	phage Terminase large subunit
D073_RS06360	COG5518	Phage portal protein
D073_RS06365	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D073_RS06370	COG4653	Phage capsid family
D073_RS06420	COG5412	phage tail tape measure protein
D073_RS06420	COG5412	phage tail tape measure protein
D073_RS06420	COG3953	SLT domain
D073_RS06420	COG3953	SLT domain
D073_RS06420	COG5412	phage tail tape measure protein
D073_RS06420	COG3953	SLT domain
D073_RS06425	COG1652	LysM domain
D073_RS06430	COG4193	domain, Protein
D073_RS06440	COG3628	GPW Gp25 family protein
D073_RS06445	COG3299	homolog of phage Mu protein gp47
D073_RS06450	COG3778	Protein conserved in bacteria
D073_RS06490	COG5632	N-Acetylmuramoyl-L-alanine amidase
D073_RS06490	COG3409	Peptidoglycan-binding domain 1 protein
D073_RS06505	COG0306	phosphate transporter
D073_RS06510	COG1392	Phosphate transport regulator
D073_RS06515	COG0531	amino acid
D073_RS06520	COG0346	lactoylglutathione lyase activity
D073_RS06525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D073_RS06530	COG0463	Glycosyl transferase, family 2
D073_RS06535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D073_RS06540	COG0477	Major facilitator Superfamily
D073_RS06545	COG2362	D-Aminopeptidase
D073_RS06550	COG0601	transmembrane transport
D073_RS06555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D073_RS06560	COG0444	Belongs to the ABC transporter superfamily
D073_RS06565	COG4166	transmembrane transport
D073_RS06570	COG1619	proteins homologs of microcin C7 resistance protein MccF
D073_RS06575	COG4948	Mandelate Racemase Muconate Lactonizing
D073_RS06580	COG0791	NLP P60 protein
D073_RS06585	COG4608	Belongs to the ABC transporter superfamily
D073_RS06590	COG2706	6-phosphogluconolactonase activity
D073_RS06595	COG1834	amidinotransferase
D073_RS06600	COG1607	acyl-coa hydrolase
D073_RS06605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D073_RS06610	COG2076	Multidrug Resistance protein
D073_RS06615	COG2076	Multidrug Resistance protein
D073_RS06620	COG0788	formyltetrahydrofolate deformylase activity
D073_RS06625	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D073_RS06635	COG1764	response to oxidative stress
D073_RS06640	COG1846	Transcriptional regulator
D073_RS06645	COG1764	response to oxidative stress
D073_RS06660	COG0463	Glycosyl transferase, family 2
D073_RS06660	COG0457	Tetratricopeptide repeat
D073_RS06670	COG2814	Major facilitator Superfamily
D073_RS06675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D073_RS06685	COG1404	Belongs to the peptidase S8 family
D073_RS06690	COG1366	Belongs to the anti-sigma-factor antagonist family
D073_RS06695	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D073_RS06700	COG1122	ATPase activity
D073_RS06705	COG4721	ABC-type cobalt transport system, permease component
D073_RS06710	COG1388	LysM domain
D073_RS06710	COG3858	chitin binding
D073_RS06730	COG2239	Acts as a magnesium transporter
D073_RS06735	COG0789	Transcriptional regulator
D073_RS06750	COG1846	Transcriptional regulator
D073_RS06755	COG0726	polysaccharide deacetylase
D073_RS06760	COG3285	dna ligase
D073_RS06760	COG1793	dna ligase
D073_RS06765	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D073_RS06770	COG0586	Pfam SNARE associated Golgi protein
D073_RS06775	COG0861	Integral membrane protein TerC family
D073_RS06780	COG1191	sigma factor activity
D073_RS06805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D073_RS06810	COG2323	membrane
D073_RS06820	COG3594	Acyltransferase
D073_RS06825	COG5002	protein histidine kinase activity
D073_RS06830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D073_RS06845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D073_RS06850	COG0436	Aminotransferase
D073_RS06880	COG3852	Histidine kinase
D073_RS06885	COG1846	Transcriptional regulator
D073_RS06890	COG1360	Flagellar Motor Protein
D073_RS06895	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D073_RS06900	COG0542	response to heat
D073_RS06910	COG3949	Membrane
D073_RS06925	COG0720	synthase
D073_RS06930	COG0602	queuosine metabolic process
D073_RS06945	COG1733	regulation of RNA biosynthetic process
D073_RS06950	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS06960	COG4641	Protein conserved in bacteria
D073_RS06960	COG1388	LysM domain
D073_RS06965	COG1388	LysM domain
D073_RS06970	COG3858	chitin binding
D073_RS06985	COG4873	Protein conserved in bacteria
D073_RS06995	COG3773	Cell wall hydrolase
D073_RS07000	COG2244	polysaccharide biosynthetic process
D073_RS07005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D073_RS07010	COG2217	Heavy metal translocating P-type atpase
D073_RS07015	COG0006	proline dipeptidase activity
D073_RS07020	COG1609	Transcriptional regulator
D073_RS07025	COG3711	transcriptional antiterminator
D073_RS07030	COG1263	PTS System
D073_RS07030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D073_RS07030	COG2190	(PTS) system
D073_RS07035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D073_RS07040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D073_RS07050	COG1533	DNA photolyase activity
D073_RS07055	COG0840	transmembrane signaling receptor activity
D073_RS07060	COG2084	Dehydrogenase
D073_RS07065	COG2340	Cysteine-rich secretory protein family
D073_RS07070	COG0768	penicillin binding
D073_RS07075	COG4191	Histidine kinase
D073_RS07080	COG0436	Aminotransferase
D073_RS07090	COG0835	chemotaxis
D073_RS07090	COG0784	Response regulator, receiver
D073_RS07100	COG2814	Major facilitator Superfamily
D073_RS07105	COG1376	ErfK ybiS ycfS ynhG family protein
D073_RS07110	COG1408	metallophosphoesterase
D073_RS07115	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS07125	COG2200	EAL domain
D073_RS07130	COG4703	Protein of unknown function (DUF1797)
D073_RS07135	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D073_RS07145	COG0517	IMP dehydrogenase activity
D073_RS07150	COG0583	DNA-binding transcription factor activity
D073_RS07155	COG0716	FMN binding
D073_RS07165	COG0716	FMN binding
D073_RS07185	COG0668	transmembrane transport
D073_RS07190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D073_RS07210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D073_RS07215	COG0303	'Molybdopterin
D073_RS07220	COG1763	Mo-molybdopterin cofactor biosynthetic process
D073_RS07225	COG0314	molybdopterin synthase activity
D073_RS07230	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D073_RS07240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D073_RS07245	COG1136	(ABC) transporter
D073_RS07250	COG0577	efflux transmembrane transporter activity
D073_RS07255	COG1349	DNA-binding transcription factor activity
D073_RS07260	COG1105	Belongs to the carbohydrate kinase PfkB family
D073_RS07265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D073_RS07265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D073_RS07265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D073_RS07270	COG0681	Belongs to the peptidase S26 family
D073_RS07280	COG0488	(ABC) transporter
D073_RS07285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D073_RS07290	COG2309	aminopeptidase activity
D073_RS07300	COG1077	Cell shape determining protein MreB Mrl
D073_RS07310	COG2002	toxin-antitoxin pair type II binding
D073_RS07315	COG3852	Histidine kinase
D073_RS07320	COG2105	PFAM AIG2 family protein
D073_RS07320	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D073_RS07325	COG0569	domain protein
D073_RS07335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D073_RS07345	COG0561	phosphatase activity
D073_RS07350	COG0242	peptide deformylase activity
D073_RS07360	COG0497	DNA recombination
D073_RS07380	COG4221	oxidoreductase activity
D073_RS07380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D073_RS07380	COG0300	oxidoreductase activity
D073_RS07380	COG3321	synthase
D073_RS07385	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS07385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS07385	COG3321	synthase
D073_RS07385	COG4221	oxidoreductase activity
D073_RS07390	COG3321	synthase
D073_RS07390	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS07390	COG0300	oxidoreductase activity
D073_RS07390	COG0318	PFAM AMP-dependent synthetase and ligase
D073_RS07390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS07395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D073_RS07395	COG0300	oxidoreductase activity
D073_RS07395	COG3321	synthase
D073_RS07395	COG4221	oxidoreductase activity
D073_RS07400	COG3321	synthase
D073_RS07400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D073_RS07400	COG0300	oxidoreductase activity
D073_RS07400	COG4221	oxidoreductase activity
D073_RS07405	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS07405	COG4221	oxidoreductase activity
D073_RS07405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS07405	COG3321	synthase
D073_RS07410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D073_RS07415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D073_RS07420	COG0022	dehydrogenase e1 component
D073_RS07425	COG0508	dehydrogenase complex catalyzes the overall conversion of
D073_RS07430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D073_RS07435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D073_RS07450	COG1982	Orn Lys Arg decarboxylase major
D073_RS07475	COG0483	inositol monophosphate 1-phosphatase activity
D073_RS07485	COG3227	Zinc metalloprotease (Elastase)
D073_RS07510	COG1217	gtp-binding protein TYPA
D073_RS07520	COG4896	Protein conserved in bacteria
D073_RS07530	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D073_RS07535	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D073_RS07540	COG2066	Belongs to the glutaminase family
D073_RS07550	COG0772	Belongs to the SEDS family
D073_RS07555	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D073_RS07570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D073_RS07570	COG2010	Cytochrome c
D073_RS07575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D073_RS07580	COG1845	cytochrome c oxidase, subunit III
D073_RS07585	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D073_RS07590	COG3336	cytochrome c oxidase
D073_RS07600	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D073_RS07605	COG2340	Cysteine-rich secretory protein family
D073_RS07620	COG3679	Belongs to the UPF0342 family
D073_RS07635	COG0742	ribosomal rna small subunit methyltransferase
D073_RS07645	COG3314	Sporulation integral membrane protein YlbJ
D073_RS07650	COG1752	Esterase of the alpha-beta hydrolase superfamily
D073_RS07655	COG3480	Lon protease (S16) C-terminal proteolytic domain
D073_RS07665	COG1399	metal-binding, possibly nucleic acid-binding protein
D073_RS07685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D073_RS07705	COG4839	cell division protein FtsL
D073_RS07710	COG0768	penicillin binding
D073_RS07715	COG0768	penicillin binding
D073_RS07735	COG0772	Belongs to the SEDS family
D073_RS07750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D073_RS07755	COG0849	cell division
D073_RS07760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D073_RS07765	COG1404	Belongs to the peptidase S8 family
D073_RS07765	COG4412	M6 family metalloprotease domain protein
D073_RS07775	COG1191	sigma factor activity
D073_RS07780	COG1191	sigma factor activity
D073_RS07785	COG1119	ATPase activity
D073_RS07790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D073_RS07795	COG1873	PFAM PRC-barrel domain
D073_RS07800	COG1496	oxidoreductase activity
D073_RS07805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D073_RS07815	COG0762	integral membrane protein
D073_RS07820	COG2302	S4 RNA-binding domain
D073_RS07825	COG3599	regulation of cell shape
D073_RS07835	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D073_RS07840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D073_RS07850	COG0564	pseudouridine synthase activity
D073_RS07860	COG2233	PERMEase
D073_RS07870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D073_RS07875	COG0505	Belongs to the CarA family
D073_RS07880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D073_RS07895	COG0284	orotidine-5'-phosphate decarboxylase activity
D073_RS07900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D073_RS07910	COG0306	phosphate transporter
D073_RS07925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D073_RS07930	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D073_RS07935	COG1648	precorrin-2 dehydrogenase activity
D073_RS07950	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D073_RS07955	COG1561	YicC-like family, N-terminal region
D073_RS07965	COG0194	GDP metabolic process
D073_RS07975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D073_RS07980	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D073_RS07985	COG0242	peptide deformylase activity
D073_RS07995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D073_RS07995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D073_RS08005	COG0631	protein serine/threonine phosphatase activity
D073_RS08010	COG0515	serine threonine protein kinase
D073_RS08010	COG2815	serine threonine protein kinase
D073_RS08020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D073_RS08025	COG1564	THIamine pyrophosphokinase
D073_RS08040	COG1302	Protein conserved in bacteria
D073_RS08045	COG1461	Dihydroxyacetone kinase
D073_RS08050	COG1760	l-serine dehydratase
D073_RS08055	COG1760	l-serine dehydratase
D073_RS08060	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D073_RS08075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D073_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS08095	COG1196	nuclear chromosome segregation
D073_RS08100	COG0552	protein localization to endoplasmic reticulum
D073_RS08115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D073_RS08125	COG1837	Belongs to the UPF0109 family
D073_RS08150	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D073_RS08165	COG2257	FlhB HrpN YscU SpaS Family
D073_RS08175	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D073_RS08180	COG0758	DNA mediated transformation
D073_RS08185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D073_RS08195	COG4974	Belongs to the 'phage' integrase family
D073_RS08215	COG1815	bacterial-type flagellum-dependent cell motility
D073_RS08220	COG1558	bacterial-type flagellum-dependent cell motility
D073_RS08225	COG1677	Flagellar hook-basal body complex protein FliE
D073_RS08230	COG1766	The M ring may be actively involved in energy transduction
D073_RS08235	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D073_RS08240	COG1317	bacterial-type flagellum organization
D073_RS08245	COG1157	protein secretion by the type III secretion system
D073_RS08250	COG2882	bacterial-type flagellum organization
D073_RS08255	COG3334	PFAM MgtE intracellular
D073_RS08260	COG3144	bacterial-type flagellum assembly
D073_RS08265	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D073_RS08270	COG4786	Flagellar basal body rod
D073_RS08275	COG1582	Flagellar protein (FlbD)
D073_RS08280	COG1580	Controls the rotational direction of flagella during chemotaxis
D073_RS08285	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D073_RS08290	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D073_RS08290	COG1776	CheC inhibitor of MCP methylation
D073_RS08295	COG2201	protein-glutamate methylesterase activity
D073_RS08300	COG3190	flagellar
D073_RS08305	COG1338	Plays a role in the flagellum-specific transport system
D073_RS08310	COG1987	bacterial-type flagellum assembly
D073_RS08315	COG1684	flagellar biosynthetic protein fliR
D073_RS08320	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D073_RS08325	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D073_RS08330	COG1419	protein localization to endoplasmic reticulum
D073_RS08335	COG0455	bacterial-type flagellum organization
D073_RS08340	COG2201	protein-glutamate methylesterase activity
D073_RS08345	COG0643	Histidine kinase
D073_RS08345	COG2198	Histidine kinase
D073_RS08350	COG0835	chemotaxis
D073_RS08355	COG1776	CheC inhibitor of MCP methylation
D073_RS08365	COG1191	sigma factor activity
D073_RS08395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D073_RS08400	COG4589	Belongs to the CDS family
D073_RS08410	COG0750	zinc metalloprotease
D073_RS08420	COG2176	DNA-directed DNA polymerase activity
D073_RS08430	COG0195	Participates in both transcription termination and antitermination
D073_RS08435	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D073_RS08440	COG1358	cellular component organization or biogenesis
D073_RS08450	COG1550	Protein conserved in bacteria
D073_RS08465	COG0196	riboflavin kinase activity
D073_RS08480	COG0726	polysaccharide deacetylase
D073_RS08485	COG0612	Peptidase, M16
D073_RS08490	COG1873	PFAM PRC-barrel domain
D073_RS08495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D073_RS08500	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D073_RS08505	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D073_RS08510	COG0527	aspartate kinase activity
D073_RS08520	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D073_RS08525	COG0740	serine-type endopeptidase activity
D073_RS08535	COG4980	gas vesicle protein
D073_RS08535	COG1674	ftsk spoiiie
D073_RS08540	COG2188	Transcriptional regulator
D073_RS08545	COG2814	Major facilitator Superfamily
D073_RS08550	COG1846	Transcriptional regulator
D073_RS08555	COG2409	Drug exporters of the RND superfamily
D073_RS08555	COG1033	growth of symbiont in host cell
D073_RS08560	COG0612	Peptidase, M16
D073_RS08565	COG0612	Peptidase, M16
D073_RS08570	COG0300	oxidoreductase activity
D073_RS08585	COG1426	Protein conserved in bacteria
D073_RS08590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D073_RS08605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D073_RS08615	COG1692	metallophosphoesterase
D073_RS08620	COG2359	stage V sporulation protein S
D073_RS08640	COG4550	Control of competence regulator ComK, YlbF/YmcA
D073_RS08660	COG0582	viral genome integration into host DNA
D073_RS08705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D073_RS08710	COG3425	synthase
D073_RS08715	COG1024	Enoyl-CoA hydratase
D073_RS08720	COG1024	Enoyl-CoA hydratase
D073_RS08725	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS08725	COG3321	synthase
D073_RS08725	COG0300	oxidoreductase activity
D073_RS08725	COG0318	PFAM AMP-dependent synthetase and ligase
D073_RS08725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS08730	COG4221	oxidoreductase activity
D073_RS08730	COG3321	synthase
D073_RS08730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D073_RS08730	COG0300	oxidoreductase activity
D073_RS08735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS08735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D073_RS08735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D073_RS08735	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS08735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS08735	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS08735	COG3321	synthase
D073_RS08735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D073_RS08735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D073_RS08735	COG3321	synthase
D073_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS08740	COG3321	synthase
D073_RS08740	COG4221	oxidoreductase activity
D073_RS08740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS08745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D073_RS08745	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D073_RS08745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D073_RS08745	COG3321	synthase
D073_RS08750	COG2124	cytochrome p450
D073_RS08755	COG3209	COG3209 Rhs family protein
D073_RS08760	COG3619	membrane
D073_RS08770	COG1404	Belongs to the peptidase S8 family
D073_RS08780	COG4195	phage-related replication protein
D073_RS08785	COG1764	response to oxidative stress
D073_RS08795	COG2076	Multidrug Resistance protein
D073_RS08835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D073_RS08840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D073_RS08845	COG4112	unkown
D073_RS08850	COG0860	N-Acetylmuramoyl-L-alanine amidase
D073_RS08860	COG0464	growth
D073_RS08865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D073_RS08870	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D073_RS08875	COG0789	Transcriptional regulator
D073_RS08880	COG0174	glutamine synthetase
D073_RS08890	COG2211	Major facilitator Superfamily
D073_RS08895	COG3507	Belongs to the glycosyl hydrolase 43 family
D073_RS08910	COG1070	Carbohydrate kinase
D073_RS08915	COG3848	Pyruvate phosphate dikinase
D073_RS08915	COG0574	Belongs to the PEP-utilizing enzyme family
D073_RS08935	COG2318	DinB family
D073_RS08940	COG1064	alcohol dehydrogenase
D073_RS09005	COG3397	chitin binding
D073_RS09025	COG5434	Belongs to the glycosyl hydrolase 28 family
D073_RS09030	COG0756	dUTP diphosphatase activity
D073_RS09035	COG4195	phage-related replication protein
D073_RS09065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D073_RS09075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D073_RS09095	COG0785	Cytochrome C biogenesis protein
D073_RS09100	COG2201	protein-glutamate methylesterase activity
D073_RS09105	COG4846	Membrane protein involved in cytochrome C biogenesis
D073_RS09115	COG0071	Belongs to the small heat shock protein (HSP20) family
D073_RS09130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D073_RS09135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D073_RS09155	COG0824	Thioesterase
D073_RS09165	COG4841	protein insertion into membrane
D073_RS09175	COG1832	CoA-binding protein
D073_RS09180	COG0187	DNA topoisomerase II activity
D073_RS09185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D073_RS09195	COG1115	amino acid carrier protein
D073_RS09205	COG1063	alcohol dehydrogenase
D073_RS09210	COG0800	Aldolase
D073_RS09215	COG1312	Catalyzes the dehydration of D-mannonate
D073_RS09220	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS09225	COG1609	Transcriptional regulator
D073_RS09230	COG2271	Major facilitator Superfamily
D073_RS09265	COG2205	protein histidine kinase activity
D073_RS09270	COG0745	RESPONSE REGULATOR receiver
D073_RS09280	COG3507	Belongs to the glycosyl hydrolase 43 family
D073_RS09305	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS09310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D073_RS09315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D073_RS09320	COG2610	gluconate transmembrane transporter activity
D073_RS09325	COG2124	cytochrome p450
D073_RS09345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D073_RS09355	COG2246	polysaccharide biosynthetic process
D073_RS09360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D073_RS09365	COG0586	Pfam SNARE associated Golgi protein
D073_RS09370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D073_RS09375	COG1024	Enoyl-CoA hydratase
D073_RS09380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D073_RS09385	COG0511	ligase activity, forming carbon-carbon bonds
D073_RS09390	COG0439	Biotin carboxylase
D073_RS09395	COG0318	PFAM AMP-dependent synthetase and ligase
D073_RS09400	COG1960	acyl-CoA dehydrogenase activity
D073_RS09405	COG1649	PFAM Uncharacterised BCR, COG1649
D073_RS09415	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D073_RS09415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS09430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS09445	COG2027	D-alanyl-D-alanine carboxypeptidase
D073_RS09450	COG2017	converts alpha-aldose to the beta-anomer
D073_RS09455	COG0534	Mate efflux family protein
D073_RS09470	COG0582	viral genome integration into host DNA
D073_RS09475	COG0166	Belongs to the GPI family
D073_RS09480	COG0405	Gamma-glutamyltransferase
D073_RS09485	COG2814	Major facilitator Superfamily
D073_RS09490	COG0640	Transcriptional regulator
D073_RS09505	COG0604	alcohol dehydrogenase
D073_RS09510	COG0493	'glutamate synthase
D073_RS09515	COG0070	glutamate synthase
D073_RS09515	COG0069	glutamate synthase activity
D073_RS09515	COG0067	glutamate synthase
D073_RS09520	COG0583	DNA-binding transcription factor activity
D073_RS09525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D073_RS09540	COG0300	oxidoreductase activity
D073_RS09545	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D073_RS09555	COG2814	Major facilitator Superfamily
D073_RS09560	COG1070	Carbohydrate kinase
D073_RS09565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D073_RS09570	COG0243	molybdopterin cofactor binding
D073_RS09605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D073_RS09610	COG0662	Cupin 2, conserved barrel domain protein
D073_RS09610	COG2207	Transcriptional regulator
D073_RS09615	COG1309	transcriptional regulator
D073_RS09620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D073_RS09630	COG0640	Transcriptional regulator
D073_RS09635	COG0741	lytic transglycosylase activity
D073_RS09640	COG2322	membrane
D073_RS09655	COG1619	proteins homologs of microcin C7 resistance protein MccF
D073_RS09665	COG1388	LysM domain
D073_RS09665	COG3584	3D domain protein
D073_RS09670	COG0514	ATP-dependent DNA helicase (RecQ)
D073_RS09680	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D073_RS09685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D073_RS09700	COG0071	Belongs to the small heat shock protein (HSP20) family
D073_RS09730	COG1012	belongs to the aldehyde dehydrogenase family
D073_RS09735	COG1657	PFAM Prenyltransferase squalene oxidase
D073_RS09740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D073_RS09745	COG0733	neurotransmitter:sodium symporter activity
D073_RS09750	COG0385	Bile acid
D073_RS09755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D073_RS09760	COG0508	dehydrogenase complex catalyzes the overall conversion of
D073_RS09770	COG4548	von Willebrand factor, type A
D073_RS09775	COG0714	Associated with various cellular activities
D073_RS09780	COG2032	superoxide dismutase activity
D073_RS09785	COG0791	NLP P60 protein
D073_RS09785	COG1388	LysM domain
D073_RS09790	COG1819	glycosyl
D073_RS09795	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D073_RS09805	COG1366	Belongs to the anti-sigma-factor antagonist family
D073_RS09810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D073_RS09815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D073_RS09825	COG2962	Rard protein
D073_RS09840	COG1942	4-Oxalocrotonate Tautomerase
D073_RS09850	COG1733	regulation of RNA biosynthetic process
D073_RS09855	COG0778	Nitroreductase
D073_RS09860	COG0400	carboxylic ester hydrolase activity
D073_RS09865	COG0346	lactoylglutathione lyase activity
D073_RS09875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D073_RS09885	COG2723	6-phospho-beta-galactosidase activity
D073_RS09890	COG2188	Transcriptional regulator
D073_RS09895	COG0793	Belongs to the peptidase S41A family
D073_RS09895	COG3409	Peptidoglycan-binding domain 1 protein
D073_RS09900	COG2226	methyltransferase
D073_RS09910	COG1876	peptidase activity
D073_RS09930	COG0671	phosphoesterase, PA-phosphatase related
D073_RS09960	COG1509	lysine 2,3-aminomutase activity
D073_RS09965	COG0456	acetyltransferase
D073_RS09970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D073_RS09975	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D073_RS09980	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D073_RS09985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D073_RS10000	COG0456	acetyltransferase
D073_RS10005	COG0463	Glycosyl transferase, family 2
D073_RS10020	COG4641	Protein conserved in bacteria
D073_RS10030	COG1086	Polysaccharide biosynthesis protein
D073_RS10045	COG1846	Transcriptional regulator
D073_RS10050	COG4698	Protein conserved in bacteria
D073_RS10055	COG2755	lipolytic protein G-D-S-L family
D073_RS10060	COG1999	signal sequence binding
D073_RS10070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D073_RS10075	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D073_RS10080	COG1272	protein, Hemolysin III
D073_RS10085	COG0204	Acyl-transferase
D073_RS10090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D073_RS10105	COG2521	methyltransferase
D073_RS10105	COG2136	Putative SAM-dependent methyltransferase
D073_RS10120	COG1413	lyase activity
D073_RS10125	COG1418	mRNA catabolic process
D073_RS10130	COG0386	Belongs to the glutathione peroxidase family
D073_RS10140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D073_RS10150	COG1278	Cold shock
D073_RS10170	COG0328	RNA-DNA hybrid ribonuclease activity
D073_RS10175	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D073_RS10180	COG0328	RNA-DNA hybrid ribonuclease activity
D073_RS10190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D073_RS10205	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D073_RS10215	COG1755	Isoprenylcysteine carboxyl methyltransferase
D073_RS10220	COG3424	synthase
D073_RS10240	COG2323	membrane
D073_RS10245	COG1335	isochorismatase
D073_RS10255	COG2233	PERMEase
D073_RS10265	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D073_RS10270	COG1199	ATP-dependent helicase activity
D073_RS10285	COG0116	Belongs to the methyltransferase superfamily
D073_RS10315	COG3359	exonuclease
D073_RS10320	COG1111	helicase
D073_RS10320	COG1205	dead DEAH box helicase
D073_RS10325	COG2190	(PTS) system
D073_RS10330	COG0071	Belongs to the small heat shock protein (HSP20) family
D073_RS10370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D073_RS10370	COG4499	WXG100 protein secretion system (Wss), protein YukC
D073_RS10380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D073_RS10385	COG3935	DnaD domain protein
D073_RS10395	COG0436	Aminotransferase
D073_RS10400	COG5353	protein conserved in bacteria
D073_RS10410	COG1199	ATP-dependent helicase activity
D073_RS10410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D073_RS10440	COG0438	transferase activity, transferring glycosyl groups
D073_RS10445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D073_RS10460	COG1694	Mazg nucleotide pyrophosphohydrolase
D073_RS10465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D073_RS10470	COG2140	Oxalate decarboxylase
D073_RS10480	COG4347	Protein of unknown function (DUF1405)
D073_RS10485	COG2010	Cytochrome c
D073_RS10485	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D073_RS10490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D073_RS10495	COG0723	plastoquinol--plastocyanin reductase activity
D073_RS10510	COG0457	Tetratricopeptide repeat
D073_RS10520	COG0287	Prephenate dehydrogenase
D073_RS10555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D073_RS10560	COG4401	Chorismate mutase type I
D073_RS10575	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D073_RS10580	COG0105	UTP biosynthetic process
D073_RS10585	COG0142	geranyltranstransferase activity
D073_RS10595	COG0142	geranyltranstransferase activity
D073_RS10610	COG0776	regulation of translation
D073_RS10615	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D073_RS10655	COG0539	negative regulation of cytoplasmic translation
D073_RS10665	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D073_RS10670	COG2959	enzyme of heme biosynthesis
D073_RS10675	COG3773	Cell wall hydrolase
D073_RS10675	COG3409	Peptidoglycan-binding domain 1 protein
D073_RS10680	COG2339	peptidase activity
D073_RS10685	COG0492	ferredoxin-NADP+ reductase activity
D073_RS10690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D073_RS10695	COG4862	establishment of competence for transformation
D073_RS10700	COG1408	metallophosphoesterase
D073_RS10710	COG1388	LysM domain
D073_RS10715	COG1266	CAAX protease self-immunity
D073_RS10720	COG0514	ATP-dependent DNA helicase (RecQ)
D073_RS10725	COG4955	Helix-turn-helix domain
D073_RS10730	COG1141	Ferredoxin
D073_RS10735	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D073_RS10740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D073_RS10750	COG1595	DNA-templated transcription, initiation
D073_RS10755	COG5002	protein histidine kinase activity
D073_RS10760	COG0745	RESPONSE REGULATOR receiver
D073_RS10765	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D073_RS10770	COG1333	cytochrome c biogenesis protein
D073_RS10775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D073_RS10780	COG1187	pseudouridine synthase activity
D073_RS10785	COG0700	Nucleoside recognition
D073_RS10790	COG2715	membrane protein required for spore maturation
D073_RS10795	COG1686	Belongs to the peptidase S11 family
D073_RS10820	COG1547	Domain of unknown function (DUF309)
D073_RS10830	COG0456	acetyltransferase
D073_RS10845	COG0307	riboflavin synthase, alpha
D073_RS10850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D073_RS10850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D073_RS10860	COG0681	Belongs to the peptidase S26 family
D073_RS10870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D073_RS10875	COG4086	secreted protein
D073_RS10880	COG0019	diaminopimelate decarboxylase activity
D073_RS10885	COG0697	spore germination
D073_RS10900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D073_RS10920	COG1191	sigma factor activity
D073_RS10930	COG1366	Belongs to the anti-sigma-factor antagonist family
D073_RS10935	COG1686	Belongs to the peptidase S11 family
D073_RS10940	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D073_RS10945	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D073_RS10950	COG4974	Belongs to the 'phage' integrase family
D073_RS10960	COG0735	belongs to the Fur family
D073_RS10965	COG1300	Membrane
D073_RS10980	COG0281	malic enzyme
D073_RS10985	COG1757	Na H antiporter
D073_RS10990	COG1027	Aspartate ammonia-lyase
D073_RS10995	COG0252	asparaginase activity
D073_RS11000	COG1396	sequence-specific DNA binding
D073_RS11005	COG1379	DNA repair
D073_RS11010	COG0494	nUDIX hydrolase
D073_RS11020	COG0667	Aldo Keto reductase
D073_RS11030	COG1073	alpha beta
D073_RS11040	COG4918	Iron-sulphur cluster biosynthesis
D073_RS11045	COG0456	acetyltransferase
D073_RS11045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D073_RS11050	COG2329	Antibiotic biosynthesis monooxygenase
D073_RS11055	COG0456	acetyltransferase
D073_RS11060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D073_RS11075	COG0628	permease
D073_RS11085	COG0346	lactoylglutathione lyase activity
D073_RS11095	COG3048	D-serine ammonia-lyase activity
D073_RS11100	COG0300	oxidoreductase activity
D073_RS11105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D073_RS11110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D073_RS11115	COG1024	Enoyl-CoA hydratase
D073_RS11120	COG3425	synthase
D073_RS11125	COG2124	cytochrome p450
D073_RS11130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D073_RS11130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D073_RS11130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS11130	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS11130	COG3321	synthase
D073_RS11135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS11135	COG3321	synthase
D073_RS11135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D073_RS11135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D073_RS11140	COG0300	oxidoreductase activity
D073_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS11140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS11140	COG0318	PFAM AMP-dependent synthetase and ligase
D073_RS11140	COG3321	synthase
D073_RS11150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS11150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D073_RS11150	COG3321	synthase
D073_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS11150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D073_RS11155	COG0300	oxidoreductase activity
D073_RS11155	COG3321	synthase
D073_RS11155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS11155	COG0318	PFAM AMP-dependent synthetase and ligase
D073_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS11160	COG3321	synthase
D073_RS11160	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS11160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D073_RS11160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D073_RS11160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS11170	COG0318	PFAM AMP-dependent synthetase and ligase
D073_RS11185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D073_RS11185	COG2070	2-Nitropropane dioxygenase
D073_RS11195	COG0250	Participates in transcription elongation, termination and antitermination
D073_RS11235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D073_RS11240	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D073_RS11255	COG0706	membrane insertase activity
D073_RS11260	COG2195	Cleaves the N-terminal amino acid of tripeptides
D073_RS11265	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D073_RS11270	COG0346	lactoylglutathione lyase activity
D073_RS11275	COG1376	ErfK ybiS ycfS ynhG family protein
D073_RS11280	COG4129	membrane
D073_RS11285	COG1126	abc transporter atp-binding protein
D073_RS11290	COG0765	amino acid transport
D073_RS11295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D073_RS11305	COG1597	lipid kinase activity
D073_RS11310	COG0508	dehydrogenase complex catalyzes the overall conversion of
D073_RS11315	COG0022	dehydrogenase e1 component
D073_RS11320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D073_RS11325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D073_RS11330	COG3426	butyrate kinase activity
D073_RS11335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D073_RS11340	COG0280	phosphate acetyltransferase
D073_RS11345	COG3829	transcription factor binding
D073_RS11345	COG3290	protein histidine kinase activity
D073_RS11355	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D073_RS11360	COG2079	MmgE PrpD family protein
D073_RS11365	COG0372	Belongs to the citrate synthase family
D073_RS11370	COG1960	acyl-CoA dehydrogenase activity
D073_RS11375	COG1250	3-hydroxyacyl-CoA dehydrogenase
D073_RS11380	COG0183	Belongs to the thiolase family
D073_RS11385	COG0584	glycerophosphoryl diester phosphodiesterase
D073_RS11390	COG0860	N-Acetylmuramoyl-L-alanine amidase
D073_RS11410	COG1902	pentaerythritol trinitrate reductase activity
D073_RS11425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D073_RS11435	COG0745	RESPONSE REGULATOR receiver
D073_RS11440	COG0750	zinc metalloprotease
D073_RS11445	COG0497	DNA recombination
D073_RS11455	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D073_RS11465	COG0142	geranyltranstransferase activity
D073_RS11475	COG1570	exodeoxyribonuclease VII activity
D073_RS11490	COG1302	Protein conserved in bacteria
D073_RS11495	COG0439	Biotin carboxylase
D073_RS11500	COG0511	ligase activity, forming carbon-carbon bonds
D073_RS11540	COG3854	ATPases associated with a variety of cellular activities
D073_RS11555	COG0006	proline dipeptidase activity
D073_RS11565	COG3872	metal-dependent enzyme
D073_RS11575	COG1752	Esterase of the alpha-beta hydrolase superfamily
D073_RS11590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D073_RS11610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D073_RS11625	COG1396	sequence-specific DNA binding
D073_RS11635	COG0681	Belongs to the peptidase S26 family
D073_RS11660	COG4940	Competence protein ComGF
D073_RS11670	COG4970	Tfp pilus assembly protein FimT
D073_RS11675	COG4537	Required for transformation and DNA binding
D073_RS11680	COG1459	type II secretion system
D073_RS11685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D073_RS11690	COG0598	Magnesium transport protein CorA
D073_RS11695	COG1253	flavin adenine dinucleotide binding
D073_RS11700	COG1366	Belongs to the anti-sigma-factor antagonist family
D073_RS11710	COG1393	Belongs to the ArsC family
D073_RS11720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D073_RS11730	COG0011	TIGRFAM Protein of
D073_RS11740	COG2866	Carboxypeptidase
D073_RS11745	COG1940	carbohydrate kinase activity
D073_RS11750	COG4483	Protein conserved in bacteria
D073_RS11755	COG1757	Na H antiporter
D073_RS11765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D073_RS11780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D073_RS11785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D073_RS11790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D073_RS11795	COG0581	inorganic phosphate transmembrane transporter activity
D073_RS11800	COG0573	inorganic phosphate transmembrane transporter activity
D073_RS11805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D073_RS11810	COG0768	penicillin binding
D073_RS11815	COG0477	Major facilitator Superfamily
D073_RS11820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D073_RS11825	COG2839	Protein conserved in bacteria
D073_RS11830	COG5521	maltodextrose utilization protein MalA
D073_RS11835	COG1388	LysM domain
D073_RS11845	COG4709	membrane
D073_RS11850	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D073_RS11855	COG0735	belongs to the Fur family
D073_RS11860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D073_RS11875	COG0513	Belongs to the DEAD box helicase family
D073_RS11890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D073_RS11895	COG2384	SAM-dependent methyltransferase
D073_RS11900	COG2010	Cytochrome c
D073_RS11905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D073_RS11910	COG0358	DNA primase activity
D073_RS11925	COG0517	IMP dehydrogenase activity
D073_RS11930	COG0751	glycine-tRNA ligase activity
D073_RS11950	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D073_RS11955	COG0295	cytidine deaminase activity
D073_RS11960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D073_RS11970	COG1480	7TM receptor with intracellular HD hydrolase
D073_RS11975	COG1702	phosphate starvation-inducible protein PhoH
D073_RS11980	COG0561	phosphatase activity
D073_RS11995	COG4864	UPF0365 protein
D073_RS12000	COG1030	water channel activity
D073_RS12005	COG1610	YqeY-like protein
D073_RS12015	COG1283	sodium-dependent phosphate transmembrane transporter activity
D073_RS12020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D073_RS12025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D073_RS12055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D073_RS12070	COG0860	N-Acetylmuramoyl-L-alanine amidase
D073_RS12085	COG1466	dna polymerase III delta subunit
D073_RS12100	COG2333	competence protein COMEC
D073_RS12100	COG0658	competence protein
D073_RS12105	COG2131	deaminase
D073_RS12110	COG1596	polysaccharide export
D073_RS12110	COG1555	photosystem II stabilization
D073_RS12115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D073_RS12120	COG2226	methyltransferase
D073_RS12125	COG0799	negative regulation of ribosome biogenesis
D073_RS12130	COG1713	HD superfamily hydrolase involved in NAD metabolism
D073_RS12140	COG1534	Rna-binding protein
D073_RS12145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D073_RS12150	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D073_RS12155	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D073_RS12165	COG2755	lipolytic protein G-D-S-L family
D073_RS12175	COG0398	Pfam SNARE associated Golgi protein
D073_RS12230	COG0512	Glutamine amidotransferase of anthranilate synthase
D073_RS12255	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D073_RS12270	COG2378	regulation of single-species biofilm formation
D073_RS12275	COG0693	protein deglycase activity
D073_RS12330	COG2207	Transcriptional regulator
D073_RS12330	COG3708	Transcriptional regulator
D073_RS12340	COG0563	adenylate kinase activity
D073_RS12350	COG2814	Major facilitator Superfamily
D073_RS12360	COG0456	acetyltransferase
D073_RS12365	COG2318	DinB family
D073_RS12375	COG0561	phosphatase activity
D073_RS12380	COG0561	phosphatase activity
D073_RS12390	COG1482	cell wall glycoprotein biosynthetic process
D073_RS12395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D073_RS12395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D073_RS12395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D073_RS12400	COG3711	transcriptional antiterminator
D073_RS12400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D073_RS12410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D073_RS12415	COG0583	DNA-binding transcription factor activity
D073_RS12420	COG2814	Major facilitator Superfamily
D073_RS12425	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D073_RS12425	COG2124	cytochrome p450
D073_RS12430	COG1309	transcriptional regulator
D073_RS12435	COG2226	methyltransferase
D073_RS12450	COG2116	formate transmembrane transporter activity
D073_RS12455	COG5609	conserved protein (DUF2294)
D073_RS12460	COG3383	formate dehydrogenase (NAD+) activity
D073_RS12465	COG2427	Protein of unknown function (DUF1641)
D073_RS12475	COG0626	cystathionine gamma-synthase activity
D073_RS12480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D073_RS12505	COG0768	penicillin binding
D073_RS12520	COG0826	peptidase U32
D073_RS12525	COG0826	peptidase U32
D073_RS12530	COG4122	O-methyltransferase activity
D073_RS12535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D073_RS12560	COG0628	permease
D073_RS12565	COG1126	abc transporter atp-binding protein
D073_RS12570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D073_RS12575	COG0765	amino acid transport
D073_RS12580	COG0765	amino acid transport
D073_RS12595	COG3881	PFAM PRC-barrel domain
D073_RS12600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D073_RS12605	COG0457	Tetratricopeptide repeat
D073_RS12615	COG1104	cysteine desulfurase activity
D073_RS12620	COG1959	2 iron, 2 sulfur cluster binding
D073_RS12625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D073_RS12630	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D073_RS12650	COG3103	Sh3 type 3 domain protein
D073_RS12650	COG0860	N-Acetylmuramoyl-L-alanine amidase
D073_RS12650	COG4991	sh3 domain protein
D073_RS12660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D073_RS12670	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D073_RS12670	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D073_RS12675	COG5416	Lipopolysaccharide assembly protein A domain
D073_RS12680	COG0490	domain, Protein
D073_RS12685	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D073_RS12685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D073_RS12695	COG2244	polysaccharide biosynthetic process
D073_RS12700	COG2323	membrane
D073_RS12710	COG1862	Preprotein translocase
D073_RS12755	COG1388	LysM domain
D073_RS12765	COG0157	Belongs to the NadC ModD family
D073_RS12770	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D073_RS12775	COG1104	cysteine desulfurase activity
D073_RS12780	COG1827	regulation of RNA biosynthetic process
D073_RS12785	COG0077	Prephenate dehydratase
D073_RS12800	COG3290	protein histidine kinase activity
D073_RS12805	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D073_RS12810	COG2868	ribosomal protein
D073_RS12820	COG1994	Peptidase M50
D073_RS12825	COG0739	heme binding
D073_RS12830	COG2894	cell division
D073_RS12840	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D073_RS12850	COG1077	Cell shape determining protein MreB Mrl
D073_RS12870	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D073_RS12875	COG0285	dihydrofolate synthase activity
D073_RS12880	COG0525	valine-tRNA ligase activity
D073_RS12890	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D073_RS12895	COG1388	LysM domain
D073_RS12905	COG0113	porphobilinogen synthase activity
D073_RS12910	COG1587	Uroporphyrinogen-III synthase
D073_RS12920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D073_RS12940	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D073_RS12945	COG0470	DNA polymerase III
D073_RS12945	COG1067	ATP-dependent peptidase activity
D073_RS12960	COG0457	Tetratricopeptide repeat
D073_RS12960	COG1477	protein flavinylation
D073_RS12975	COG0473	3-isopropylmalate dehydrogenase activity
D073_RS12990	COG0440	acetolactate synthase activity
D073_RS12995	COG0028	Belongs to the TPP enzyme family
D073_RS13020	COG0622	Phosphoesterase
D073_RS13025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D073_RS13035	COG5401	PFAM Sporulation and spore germination
D073_RS13045	COG1846	Transcriptional regulator
D073_RS13050	COG2197	response regulator
D073_RS13055	COG0824	Thioesterase
D073_RS13060	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D073_RS13065	COG1053	succinate dehydrogenase
D073_RS13070	COG2009	succinate dehydrogenase
D073_RS13075	COG1719	4-vinyl reductase, 4VR
D073_RS13080	COG0527	aspartate kinase activity
D073_RS13095	COG3118	belongs to the thioredoxin family
D073_RS13100	COG3534	alpha-L-arabinofuranosidase
D073_RS13105	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D073_RS13110	COG2086	electron transfer activity
D073_RS13115	COG1024	Enoyl-CoA hydratase
D073_RS13120	COG1309	transcriptional regulator
D073_RS13125	COG0318	PFAM AMP-dependent synthetase and ligase
D073_RS13135	COG3766	membrane
D073_RS13145	COG1796	DNA polymerase
D073_RS13145	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D073_RS13150	COG1286	toxin biosynthetic process
D073_RS13165	COG0072	phenylalanine-tRNA ligase activity
D073_RS13165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D073_RS13170	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D073_RS13175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D073_RS13185	COG3835	regulator
D073_RS13190	COG0277	FAD linked oxidase domain protein
D073_RS13195	COG0247	lactate metabolic process
D073_RS13200	COG1966	Carbon starvation protein
D073_RS13205	COG3534	alpha-L-arabinofuranosidase
D073_RS13210	COG0395	ABC-type sugar transport system, permease component
D073_RS13215	COG1175	transmembrane transport
D073_RS13220	COG1653	transport
D073_RS13230	COG0647	UMP catabolic process
D073_RS13235	COG0235	Class ii aldolase
D073_RS13240	COG1069	ribulokinase activity
D073_RS13245	COG2160	L-arabinose isomerase activity
D073_RS13250	COG3507	Belongs to the glycosyl hydrolase 43 family
D073_RS13255	COG1363	Peptidase, m42
D073_RS13265	COG3326	Membrane
D073_RS13270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D073_RS13280	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D073_RS13285	COG1346	cytolysis
D073_RS13290	COG1380	Effector of murein hydrolase LrgA
D073_RS13295	COG3279	Response regulator of the LytR AlgR family
D073_RS13300	COG3275	phosphorelay sensor kinase activity
D073_RS13305	COG1011	Hydrolase
D073_RS13320	COG0398	Pfam SNARE associated Golgi protein
D073_RS13325	COG1484	DNA-dependent DNA replication
D073_RS13330	COG3611	Membrane attachment protein
D073_RS13345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D073_RS13350	COG1733	regulation of RNA biosynthetic process
D073_RS13355	COG2814	Major facilitator Superfamily
D073_RS13360	COG0656	L-ascorbic acid biosynthetic process
D073_RS13365	COG0237	dephospho-CoA kinase activity
D073_RS13370	COG1971	Probably functions as a manganese efflux pump
D073_RS13375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D073_RS13380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D073_RS13380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D073_RS13385	COG5002	protein histidine kinase activity
D073_RS13390	COG0745	RESPONSE REGULATOR receiver
D073_RS13400	COG0538	isocitrate dehydrogenase activity
D073_RS13405	COG0372	Belongs to the citrate synthase family
D073_RS13410	COG0457	Tetratricopeptide repeat
D073_RS13435	COG0628	permease
D073_RS13440	COG3030	protein affecting phage T7 exclusion by the F plasmid
D073_RS13445	COG0469	pyruvate kinase activity
D073_RS13465	COG0281	malic enzyme
D073_RS13470	COG0587	DNA-directed DNA polymerase activity
D073_RS13490	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D073_RS13500	COG4109	DRTGG domain
D073_RS13510	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS13525	COG0521	Mo-molybdopterin cofactor biosynthetic process
D073_RS13535	COG0827	DNA restriction-modification system
D073_RS13540	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D073_RS13545	COG3874	Sporulation protein YtfJ
D073_RS13555	COG1714	RDD family
D073_RS13560	COG0616	signal peptide processing
D073_RS13565	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D073_RS13570	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D073_RS13575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D073_RS13590	COG1104	cysteine desulfurase activity
D073_RS13595	COG1114	Component of the transport system for branched-chain amino acids
D073_RS13605	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D073_RS13610	COG1309	transcriptional regulator
D073_RS13615	COG1956	GAF domain-containing protein
D073_RS13620	COG2203	Gaf domain
D073_RS13620	COG2199	diguanylate cyclase activity
D073_RS13635	COG1012	belongs to the aldehyde dehydrogenase family
D073_RS13640	COG4282	regulation of fungal-type cell wall biogenesis
D073_RS13675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D073_RS13675	COG1017	nitric oxide dioxygenase activity
D073_RS13685	COG0693	protein deglycase activity
D073_RS13700	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D073_RS13705	COG1378	Sugar-specific transcriptional regulator TrmB
D073_RS13730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D073_RS13735	COG0454	-acetyltransferase
D073_RS13740	COG0517	IMP dehydrogenase activity
D073_RS13745	COG0123	including yeast histone deacetylase and acetoin utilization protein
D073_RS13750	COG1360	Flagellar Motor Protein
D073_RS13755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D073_RS13760	COG1609	Transcriptional regulator
D073_RS13765	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D073_RS13765	COG1605	Chorismate mutase
D073_RS13770	COG3118	belongs to the thioredoxin family
D073_RS13775	COG4980	gas vesicle protein
D073_RS13780	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D073_RS13790	COG1674	ftsk spoiiie
D073_RS13795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D073_RS13805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D073_RS13825	COG1363	Peptidase, m42
D073_RS13830	COG5584	Small secreted protein
D073_RS13835	COG0281	malic enzyme
D073_RS13840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D073_RS13855	COG0510	thiamine kinase activity
D073_RS13860	COG1597	lipid kinase activity
D073_RS13870	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D073_RS13875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D073_RS13880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D073_RS13885	COG2252	PERMEase
D073_RS13890	COG4473	ABC transporter
D073_RS13895	COG1131	(ABC) transporter
D073_RS13900	COG1349	DNA-binding transcription factor activity
D073_RS13905	COG1187	pseudouridine synthase activity
D073_RS13910	COG2244	polysaccharide biosynthetic process
D073_RS13915	COG2081	HI0933 family
D073_RS13925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D073_RS13935	COG1609	Transcriptional regulator
D073_RS13940	COG1653	transport
D073_RS13945	COG1175	transmembrane transport
D073_RS13950	COG0395	ABC-type sugar transport system, permease component
D073_RS13955	COG1486	melibiose metabolic process
D073_RS13965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D073_RS13980	COG2202	Pas domain
D073_RS13980	COG1366	Belongs to the anti-sigma-factor antagonist family
D073_RS13985	COG2814	Major facilitator Superfamily
D073_RS13990	COG5522	Integral membrane protein (intg_mem_TP0381)
D073_RS13995	COG0577	efflux transmembrane transporter activity
D073_RS14000	COG1136	(ABC) transporter
D073_RS14005	COG2205	protein histidine kinase activity
D073_RS14010	COG0745	RESPONSE REGULATOR receiver
D073_RS14015	COG0577	efflux transmembrane transporter activity
D073_RS14020	COG1136	(ABC) transporter
D073_RS14040	COG1131	(ABC) transporter
D073_RS14045	COG1725	Transcriptional regulator
D073_RS14055	COG1242	4 iron, 4 sulfur cluster binding
D073_RS14060	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D073_RS14070	COG0584	glycerophosphoryl diester phosphodiesterase
D073_RS14080	COG2267	carboxylic ester hydrolase activity
D073_RS14085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D073_RS14090	COG1113	amino acid transport
D073_RS14095	COG0367	asparagine synthase
D073_RS14115	COG1506	peptidase
D073_RS14120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D073_RS14125	COG1116	anion transmembrane transporter activity
D073_RS14130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D073_RS14135	COG0494	nUDIX hydrolase
D073_RS14140	COG4824	toxin secretion phage lysis holin
D073_RS14145	COG0783	Belongs to the Dps family
D073_RS14170	COG0288	reversible hydration of carbon dioxide
D073_RS14180	COG1271	oxidase subunit
D073_RS14185	COG1294	oxidase, subunit
D073_RS14200	COG4948	Mandelate Racemase Muconate Lactonizing
D073_RS14210	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D073_RS14215	COG0596	Alpha beta hydrolase
D073_RS14225	COG1169	isochorismate synthase
D073_RS14230	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D073_RS14235	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D073_RS14370	COG3859	Proton-coupled thiamine transporter YuaJ
D073_RS14375	COG2268	Band 7 protein
D073_RS14380	COG1585	Membrane protein implicated in regulation of membrane protease activity
D073_RS14385	COG2318	DinB family
D073_RS14395	COG1454	alcohol dehydrogenase
D073_RS14400	COG1012	belongs to the aldehyde dehydrogenase family
D073_RS14405	COG1510	regulation of RNA biosynthetic process
D073_RS14415	COG0569	domain protein
D073_RS14420	COG1705	Flagellar rod assembly protein muramidase FlgJ
D073_RS14425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D073_RS14425	COG1017	nitric oxide dioxygenase activity
D073_RS14450	COG0628	permease
D073_RS14455	COG0673	inositol 2-dehydrogenase activity
D073_RS14460	COG0693	protein deglycase activity
D073_RS14465	COG0840	transmembrane signaling receptor activity
D073_RS14470	COG0840	transmembrane signaling receptor activity
D073_RS14475	COG0840	transmembrane signaling receptor activity
D073_RS14480	COG0840	transmembrane signaling receptor activity
D073_RS14495	COG2070	2-Nitropropane dioxygenase
D073_RS14500	COG0432	Pfam Uncharacterised protein family UPF0047
D073_RS14505	COG0366	Alpha amylase catalytic
D073_RS14510	COG1253	flavin adenine dinucleotide binding
D073_RS14515	COG2738	Putative neutral zinc metallopeptidase
D073_RS14530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D073_RS14560	COG1335	isochorismatase
D073_RS14565	COG1979	alcohol dehydrogenase
D073_RS14570	COG1979	alcohol dehydrogenase
D073_RS14575	COG2155	Conserved Protein
D073_RS14580	COG1098	S1 RNA binding domain
D073_RS14585	COG0436	Aminotransferase
D073_RS14590	COG1522	sequence-specific DNA binding
D073_RS14595	COG2267	carboxylic ester hydrolase activity
D073_RS14605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D073_RS14610	COG2205	protein histidine kinase activity
D073_RS14620	COG5018	Exonuclease
D073_RS14625	COG2814	Major facilitator Superfamily
D073_RS14630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D073_RS14635	COG3011	Protein conserved in bacteria
D073_RS14645	COG3290	protein histidine kinase activity
D073_RS14650	COG4565	transcriptional regulatory protein
D073_RS14655	COG1744	ABC transporter substrate-binding protein PnrA-like
D073_RS14660	COG3845	ABC transporter
D073_RS14665	COG4603	Belongs to the binding-protein-dependent transport system permease family
D073_RS14670	COG1079	Belongs to the binding-protein-dependent transport system permease family
D073_RS14680	COG2111	Na H antiporter
D073_RS14680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D073_RS14685	COG2111	Na H antiporter
D073_RS14690	COG1006	Multisubunit Na H antiporter MnhC subunit
D073_RS14695	COG0651	ATP synthesis coupled electron transport
D073_RS14700	COG1863	multisubunit Na H antiporter MnhE subunit
D073_RS14705	COG2212	antiporter activity
D073_RS14710	COG1320	monovalent cation:proton antiporter activity
D073_RS14715	COG2050	protein possibly involved in aromatic compounds catabolism
D073_RS14720	COG2197	response regulator
D073_RS14725	COG4585	Histidine kinase
D073_RS14735	COG0142	geranyltranstransferase activity
D073_RS14755	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D073_RS14760	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D073_RS14765	COG1335	isochorismatase
D073_RS14770	COG5506	Protein of unknown function (DUF1694)
D073_RS14785	COG0628	permease
D073_RS14795	COG1418	mRNA catabolic process
D073_RS14800	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS14810	COG1511	domain protein
D073_RS14815	COG0433	COG0433 Predicted ATPase
D073_RS14815	COG1674	ftsk spoiiie
D073_RS14820	COG4499	WXG100 protein secretion system (Wss), protein YukC
D073_RS14825	COG5417	Belongs to the EsaB family
D073_RS14830	COG4842	Belongs to the WXG100 family
D073_RS14835	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D073_RS14835	COG2508	Transcriptional regulator
D073_RS14840	COG0686	Belongs to the AlaDH PNT family
D073_RS14845	COG5634	Uncharacterized conserved protein (DUF2278)
D073_RS14850	COG3251	PFAM MbtH domain protein
D073_RS14855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D073_RS14860	COG3433	isochorismatase activity
D073_RS14860	COG1535	isochorismatase
D073_RS14865	COG1021	2,3-dihydroxybenzoate-AMP ligase
D073_RS14870	COG1169	isochorismate synthase
D073_RS14875	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS14880	COG2819	hydrolase of the alpha beta superfamily
D073_RS14885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D073_RS14890	COG1268	BioY protein
D073_RS14895	COG2056	Na+-H+ antiporter family
D073_RS14905	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D073_RS14910	COG3584	3D domain protein
D073_RS14925	COG1252	NADH dehydrogenase
D073_RS14955	COG1131	(ABC) transporter
D073_RS14975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D073_RS14980	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D073_RS14985	COG0316	Belongs to the HesB IscA family
D073_RS14995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D073_RS15005	COG1252	NADH dehydrogenase
D073_RS15010	COG4837	Protein of unknown function (DUF1462)
D073_RS15015	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D073_RS15020	COG4946	Tricorn protease homolog
D073_RS15020	COG1506	peptidase
D073_RS15020	COG0823	Involved in the tonB-independent uptake of proteins
D073_RS15030	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D073_RS15035	COG0460	homoserine dehydrogenase
D073_RS15040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D073_RS15045	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D073_RS15050	COG0647	UMP catabolic process
D073_RS15055	COG2445	Protein of unknown function DUF86
D073_RS15060	COG4470	Protein conserved in bacteria
D073_RS15075	COG0739	heme binding
D073_RS15085	COG0737	Belongs to the 5'-nucleotidase family
D073_RS15090	COG0730	response to heat
D073_RS15095	COG1801	Protein of unknown function DUF72
D073_RS15110	COG2508	Transcriptional regulator
D073_RS15125	COG2814	Major facilitator Superfamily
D073_RS15130	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D073_RS15135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D073_RS15140	COG2356	endonuclease I
D073_RS15145	COG3842	ATPase activity
D073_RS15150	COG2188	Transcriptional regulator
D073_RS15155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D073_RS15160	COG0395	ABC-type sugar transport system, permease component
D073_RS15165	COG1175	transmembrane transport
D073_RS15170	COG1653	transport
D073_RS15175	COG2222	sugar isomerase
D073_RS15180	COG0789	Transcriptional regulator
D073_RS15205	COG0322	excinuclease ABC activity
D073_RS15210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D073_RS15215	COG2226	methyltransferase
D073_RS15230	COG3409	Peptidoglycan-binding domain 1 protein
D073_RS15235	COG0719	Fe-S assembly protein
D073_RS15240	COG0822	iron-sulfur transferase activity
D073_RS15245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D073_RS15250	COG0719	Fe-S assembly protein
D073_RS15255	COG0396	ATPase activity
D073_RS15265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D073_RS15270	COG1464	Belongs to the NlpA lipoprotein family
D073_RS15275	COG2011	ABC-type metal ion transport system permease component
D073_RS15280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D073_RS15290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D073_RS15295	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D073_RS15310	COG1393	Belongs to the ArsC family
D073_RS15315	COG1960	acyl-CoA dehydrogenase activity
D073_RS15320	COG0183	Belongs to the thiolase family
D073_RS15325	COG1250	3-hydroxyacyl-CoA dehydrogenase
D073_RS15325	COG1024	Enoyl-CoA hydratase
D073_RS15345	COG5577	PFAM Coat F domain
D073_RS15350	COG1846	Transcriptional regulator
D073_RS15355	COG0477	Major facilitator Superfamily
D073_RS15360	COG0583	DNA-binding transcription factor activity
D073_RS15380	COG1120	ATPase activity
D073_RS15395	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS15400	COG0783	Belongs to the Dps family
D073_RS15405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D073_RS15415	COG0745	RESPONSE REGULATOR receiver
D073_RS15420	COG2770	Histidine kinase
D073_RS15420	COG2205	protein histidine kinase activity
D073_RS15430	COG1309	transcriptional regulator
D073_RS15435	COG0114	fumarate hydratase activity
D073_RS15445	COG0697	spore germination
D073_RS15450	COG0814	amino acid
D073_RS15460	COG2197	response regulator
D073_RS15465	COG4585	Histidine kinase
D073_RS15470	COG4758	membrane
D073_RS15475	COG3595	metallopeptidase activity
D073_RS15480	COG1842	Phage shock protein A
D073_RS15485	COG4758	membrane
D073_RS15490	COG2814	Major facilitator Superfamily
D073_RS15495	COG2096	Adenosyltransferase
D073_RS15500	COG1120	ATPase activity
D073_RS15505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D073_RS15510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D073_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS15520	COG3386	PFAM SMP-30 Gluconolaconase
D073_RS15525	COG2205	protein histidine kinase activity
D073_RS15530	COG0745	RESPONSE REGULATOR receiver
D073_RS15540	COG1191	sigma factor activity
D073_RS15550	COG2140	Oxalate decarboxylase
D073_RS15560	COG1120	ATPase activity
D073_RS15565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D073_RS15570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D073_RS15575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D073_RS15580	COG0531	amino acid
D073_RS15595	COG1988	membrane-bound metal-dependent
D073_RS15600	COG1368	sulfuric ester hydrolase activity
D073_RS15605	COG1910	domain protein
D073_RS15610	COG0725	ABC transporter, periplasmic molybdate-binding protein
D073_RS15615	COG4149	molybdate abc transporter
D073_RS15620	COG2197	response regulator
D073_RS15625	COG3850	Histidine kinase
D073_RS15630	COG1131	(ABC) transporter
D073_RS15640	COG0842	Transport permease protein
D073_RS15645	COG0656	L-ascorbic acid biosynthetic process
D073_RS15670	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D073_RS15675	COG3973	AAA domain
D073_RS15680	COG2860	membrane
D073_RS15690	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D073_RS15695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D073_RS15700	COG2217	Heavy metal translocating P-type atpase
D073_RS15705	COG2217	Heavy metal translocating P-type atpase
D073_RS15710	COG2608	mercury ion transmembrane transporter activity
D073_RS15715	COG1937	Protein conserved in bacteria
D073_RS15720	COG0673	inositol 2-dehydrogenase activity
D073_RS15730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D073_RS15735	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D073_RS15740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D073_RS15745	COG1126	abc transporter atp-binding protein
D073_RS15750	COG0765	amino acid transport
D073_RS15755	COG0765	amino acid transport
D073_RS15760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D073_RS15765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D073_RS15770	COG0454	-acetyltransferase
D073_RS15780	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS15785	COG2732	(Barnase) inhibitor
D073_RS15810	COG0557	exoribonuclease II activity
D073_RS15815	COG1647	Serine aminopeptidase, S33
D073_RS15820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D073_RS15825	COG1476	TRANSCRIPTIONal
D073_RS15830	COG1396	sequence-specific DNA binding
D073_RS15835	COG1396	sequence-specific DNA binding
D073_RS15840	COG1733	regulation of RNA biosynthetic process
D073_RS15865	COG1131	(ABC) transporter
D073_RS15870	COG1174	glycine betaine transport
D073_RS15875	COG1732	Glycine betaine
D073_RS15880	COG1174	glycine betaine transport
D073_RS15885	COG1125	glycine betaine transport
D073_RS15885	COG0517	IMP dehydrogenase activity
D073_RS15890	COG1510	regulation of RNA biosynthetic process
D073_RS15895	COG1174	glycine betaine transport
D073_RS15900	COG1732	Glycine betaine
D073_RS15905	COG1174	glycine betaine transport
D073_RS15910	COG0517	IMP dehydrogenase activity
D073_RS15910	COG1125	glycine betaine transport
D073_RS15915	COG1510	regulation of RNA biosynthetic process
D073_RS15920	COG2095	MarC family integral membrane protein
D073_RS15935	COG4640	response to antibiotic
D073_RS15940	COG0456	acetyltransferase
D073_RS15955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D073_RS15975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D073_RS15980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D073_RS15990	COG2234	aminopeptidase activity
D073_RS16010	COG0126	phosphoglycerate kinase activity
D073_RS16020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D073_RS16025	COG2390	Transcriptional regulator
D073_RS16030	COG2814	Major facilitator Superfamily
D073_RS16040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D073_RS16050	COG0583	DNA-binding transcription factor activity
D073_RS16055	COG0697	spore germination
D073_RS16060	COG1113	amino acid transport
D073_RS16065	COG1737	Transcriptional regulator
D073_RS16070	COG1070	Carbohydrate kinase
D073_RS16095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D073_RS16100	COG2186	Transcriptional regulator
D073_RS16105	COG1620	l-lactate permease
D073_RS16110	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D073_RS16120	COG5039	Polysaccharide pyruvyl transferase
D073_RS16125	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D073_RS16130	COG0110	maltose O-acetyltransferase activity
D073_RS16135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D073_RS16140	COG2244	polysaccharide biosynthetic process
D073_RS16145	COG1216	Glycosyl transferase, family 2
D073_RS16150	COG5039	Polysaccharide pyruvyl transferase
D073_RS16155	COG1216	Glycosyl transferase, family 2
D073_RS16165	COG0438	transferase activity, transferring glycosyl groups
D073_RS16170	COG1215	transferase activity, transferring glycosyl groups
D073_RS16175	COG0438	transferase activity, transferring glycosyl groups
D073_RS16180	COG1086	Polysaccharide biosynthesis protein
D073_RS16185	COG0489	protein tyrosine kinase activity
D073_RS16190	COG3944	biosynthesis protein
D073_RS16195	COG1396	sequence-specific DNA binding
D073_RS16200	COG2272	Belongs to the type-B carboxylesterase lipase family
D073_RS16210	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D073_RS16215	COG2364	Membrane
D073_RS16220	COG0456	acetyltransferase
D073_RS16225	COG3479	Phenolic acid decarboxylase
D073_RS16275	COG2223	nitrite transmembrane transporter activity
D073_RS16280	COG1609	Transcriptional regulator
D073_RS16290	COG0583	DNA-binding transcription factor activity
D073_RS16295	COG2828	Protein conserved in bacteria
D073_RS16300	COG0477	Major facilitator Superfamily
D073_RS16300	COG2814	Major facilitator Superfamily
D073_RS16305	COG1611	Belongs to the LOG family
D073_RS16310	COG1694	Mazg nucleotide pyrophosphohydrolase
D073_RS16315	COG0659	secondary active sulfate transmembrane transporter activity
D073_RS16320	COG0288	reversible hydration of carbon dioxide
D073_RS16330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D073_RS16335	COG4290	ribonuclease
D073_RS16340	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D073_RS16345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D073_RS16355	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D073_RS16365	COG1051	belongs to the nudix hydrolase family
D073_RS16370	COG0492	ferredoxin-NADP+ reductase activity
D073_RS16375	COG0791	NLP P60 protein
D073_RS16375	COG3883	PFAM NLP P60 protein
D073_RS16380	COG0457	Tetratricopeptide repeat
D073_RS16385	COG5002	protein histidine kinase activity
D073_RS16390	COG0745	RESPONSE REGULATOR receiver
D073_RS16395	COG1132	(ABC) transporter
D073_RS16400	COG0140	phosphoribosyl-ATP diphosphatase activity
D073_RS16400	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D073_RS16425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D073_RS16440	COG4990	cell redox homeostasis
D073_RS16445	COG0110	maltose O-acetyltransferase activity
D073_RS16465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D073_RS16475	COG2188	Transcriptional regulator
D073_RS16480	COG1309	transcriptional regulator
D073_RS16485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D073_RS16490	COG1950	PFAM Membrane protein of
D073_RS16495	COG1983	PspC domain protein
D073_RS16500	COG3595	metallopeptidase activity
D073_RS16515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D073_RS16525	COG4897	Protein conserved in bacteria
D073_RS16530	COG3848	Pyruvate phosphate dikinase
D073_RS16530	COG0574	Belongs to the PEP-utilizing enzyme family
D073_RS16535	COG1309	transcriptional regulator
D073_RS16540	COG2814	Major facilitator Superfamily
D073_RS16555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D073_RS16565	COG3409	Peptidoglycan-binding domain 1 protein
D073_RS16565	COG0793	Belongs to the peptidase S41A family
D073_RS16570	COG3420	alginic acid biosynthetic process
D073_RS16575	COG2177	Part of the ABC transporter FtsEX involved in
D073_RS16580	COG2884	Cell division ATP-binding protein ftsE
D073_RS16585	COG2010	Cytochrome c
D073_RS16590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D073_RS16605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D073_RS16620	COG1516	flagellar protein fliS
D073_RS16625	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D073_RS16630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D073_RS16650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D073_RS16655	COG1256	bacterial-type flagellum assembly
D073_RS16655	COG4786	Flagellar basal body rod
D073_RS16660	COG3418	PFAM FlgN family protein
D073_RS16665	COG2747	anti-sigma28 factor FlgM
D073_RS16675	COG1040	competence protein
D073_RS16685	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D073_RS16690	COG1307	EDD domain protein, DegV family
D073_RS16695	COG2197	response regulator
D073_RS16700	COG4585	Histidine kinase
D073_RS16705	COG1739	Uncharacterized protein family UPF0029
D073_RS16710	COG1316	TRANSCRIPTIONal
D073_RS16715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D073_RS16720	COG0438	transferase activity, transferring glycosyl groups
D073_RS16725	COG1215	transferase activity, transferring glycosyl groups
D073_RS16730	COG3206	protein involved in exopolysaccharide biosynthesis
D073_RS16735	COG3307	-O-antigen
D073_RS16740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D073_RS16745	COG0438	transferase activity, transferring glycosyl groups
D073_RS16745	COG0297	glycogen (starch) synthase activity
D073_RS16750	COG2244	polysaccharide biosynthetic process
D073_RS16760	COG0860	N-Acetylmuramoyl-L-alanine amidase
D073_RS16760	COG2247	cell wall binding repeat
D073_RS16765	COG2385	sporulation resulting in formation of a cellular spore
D073_RS16765	COG2247	cell wall binding repeat
D073_RS16775	COG1316	TRANSCRIPTIONal
D073_RS16780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D073_RS16785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D073_RS16790	COG1134	teichoic acid transport
D073_RS16795	COG1682	transport, permease protein
D073_RS16800	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D073_RS16810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D073_RS16815	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D073_RS16820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D073_RS16825	COG4193	domain, Protein
D073_RS16830	COG1482	cell wall glycoprotein biosynthetic process
D073_RS16835	COG0697	spore germination
D073_RS16840	COG0814	amino acid
D073_RS16850	COG1215	transferase activity, transferring glycosyl groups
D073_RS16855	COG2814	Major facilitator Superfamily
D073_RS16860	COG1316	TRANSCRIPTIONal
D073_RS16865	COG0561	phosphatase activity
D073_RS16870	COG2433	Pfam Transposase IS66
D073_RS16875	COG0791	NLP P60 protein
D073_RS16885	COG2843	Capsule synthesis protein
D073_RS16895	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D073_RS16905	COG0697	spore germination
D073_RS16910	COG0814	amino acid
D073_RS16920	COG1609	Transcriptional regulator
D073_RS16925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D073_RS16935	COG1129	ABC transporter
D073_RS16940	COG1172	Belongs to the binding-protein-dependent transport system permease family
D073_RS16945	COG1879	ABC-type sugar transport system periplasmic component
D073_RS16950	COG3103	Sh3 type 3 domain protein
D073_RS16955	COG2249	NAD(P)H dehydrogenase (quinone) activity
D073_RS16960	COG3527	Alpha-acetolactate decarboxylase
D073_RS16965	COG0028	Belongs to the TPP enzyme family
D073_RS16970	COG0583	DNA-binding transcription factor activity
D073_RS16975	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D073_RS16990	COG5337	Spore coat protein CotH
D073_RS17000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D073_RS17010	COG0405	Gamma-glutamyltransferase
D073_RS17015	COG1522	sequence-specific DNA binding
D073_RS17020	COG2059	Chromate
D073_RS17025	COG2059	Chromate
D073_RS17040	COG5444	nuclease activity
D073_RS17055	COG3878	Protein conserved in bacteria
D073_RS17060	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D073_RS17065	COG4464	protein tyrosine phosphatase activity
D073_RS17070	COG0489	protein tyrosine kinase activity
D073_RS17075	COG3944	biosynthesis protein
D073_RS17090	COG4715	Zinc finger, swim domain protein
D073_RS17095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D073_RS17100	COG0561	phosphatase activity
D073_RS17105	COG1349	DNA-binding transcription factor activity
D073_RS17110	COG0629	single-stranded DNA binding
D073_RS17135	COG0457	Tetratricopeptide repeat
D073_RS17140	COG4786	Flagellar basal body rod
D073_RS17145	COG4786	Flagellar basal body rod
D073_RS17150	COG1077	Cell shape determining protein MreB Mrl
D073_RS17155	COG1609	Transcriptional regulator
D073_RS17160	COG1846	Transcriptional regulator
D073_RS17165	COG2814	Major facilitator Superfamily
D073_RS17170	COG1953	Uracil, thiamine, allantoin
D073_RS17175	COG0477	Major facilitator Superfamily
D073_RS17180	COG1335	isochorismatase
D073_RS17185	COG0004	ammonium transporteR
D073_RS17190	COG0347	Belongs to the P(II) protein family
D073_RS17195	COG0772	Belongs to the SEDS family
D073_RS17200	COG0671	phosphoesterase, PA-phosphatase related
D073_RS17210	COG0739	heme binding
D073_RS17215	COG1247	-acetyltransferase
D073_RS17230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D073_RS17245	COG0726	polysaccharide deacetylase
D073_RS17250	COG1959	2 iron, 2 sulfur cluster binding
D073_RS17265	COG0831	urea catabolic process
D073_RS17270	COG3237	CsbD-like
D073_RS17275	COG1994	Peptidase M50
D073_RS17280	COG0457	Tetratricopeptide repeat
D073_RS17290	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D073_RS17295	COG2304	oxidoreductase activity
D073_RS17300	COG2304	oxidoreductase activity
D073_RS17310	COG2385	sporulation resulting in formation of a cellular spore
D073_RS17315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D073_RS17325	COG4836	Membrane
D073_RS17395	COG0698	ribose 5-phosphate isomerase
D073_RS17400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D073_RS17410	COG0009	L-threonylcarbamoyladenylate synthase
D073_RS17415	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D073_RS17435	COG2890	protein-(glutamine-N5) methyltransferase activity
D073_RS17440	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D073_RS17445	COG0346	lactoylglutathione lyase activity
D073_RS17450	COG0789	Transcriptional regulator
D073_RS17455	COG0679	Auxin Efflux Carrier
D073_RS17460	COG0281	malic enzyme
D073_RS17475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D073_RS17480	COG1494	fructose-1,6-bisphosphatase
D073_RS17485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D073_RS17495	COG0191	fructose-bisphosphate aldolase activity
D073_RS17500	COG2204	response regulator
D073_RS17505	COG4821	SIS domain
D073_RS17520	COG0247	lactate metabolic process
D073_RS17520	COG2181	nitrate reductase activity
D073_RS17525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D073_RS17540	COG1132	(ABC) transporter
D073_RS17545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D073_RS17555	COG2181	nitrate reductase activity
D073_RS17560	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D073_RS17565	COG1140	nitrate reductase beta subunit
D073_RS17570	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D073_RS17575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D073_RS17585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D073_RS17590	COG2223	nitrite transmembrane transporter activity
D073_RS17600	COG4506	Protein conserved in bacteria
D073_RS17610	COG3391	amine dehydrogenase activity
D073_RS17615	COG3391	amine dehydrogenase activity
D073_RS17625	COG0457	Tetratricopeptide repeat
D073_RS17670	COG0010	Belongs to the arginase family
D073_RS17675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D073_RS17680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D073_RS17695	COG1994	Peptidase M50
D073_RS17700	COG1942	4-Oxalocrotonate Tautomerase
D073_RS17705	COG1846	Transcriptional regulator
D073_RS17715	COG0531	amino acid
D073_RS17720	COG3465	dGTPase activity
D073_RS17725	COG1078	dGTPase activity
D073_RS17740	COG1695	Transcriptional regulator
D073_RS17750	COG1131	(ABC) transporter
D073_RS17755	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D073_RS17785	COG0583	DNA-binding transcription factor activity
D073_RS17790	COG2855	membrane
D073_RS17795	COG0280	phosphate acetyltransferase
D073_RS17805	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS17810	COG0436	Aminotransferase
D073_RS17840	COG2814	Major facilitator Superfamily
D073_RS17845	COG2814	Major facilitator Superfamily
D073_RS17850	COG0833	amino acid
D073_RS17855	COG4187	Peptidase family M20/M25/M40
D073_RS17860	COG1012	belongs to the aldehyde dehydrogenase family
D073_RS17865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D073_RS17875	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D073_RS17880	COG1091	dTDP-4-dehydrorhamnose reductase activity
D073_RS17885	COG1088	dTDP-glucose 4,6-dehydratase activity
D073_RS17890	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D073_RS17895	COG3980	spore coat polysaccharide biosynthesis protein
D073_RS17900	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D073_RS17905	COG2089	acid synthase
D073_RS17910	COG0456	acetyltransferase
D073_RS17915	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D073_RS17920	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D073_RS17925	COG0463	Glycosyl transferase, family 2
D073_RS17935	COG2363	Small membrane protein
D073_RS17940	COG2233	PERMEase
D073_RS17955	COG1216	Glycosyl transferase, family 2
D073_RS17970	COG1695	Transcriptional regulator
D073_RS17975	COG0351	phosphomethylpyrimidine kinase
D073_RS17985	COG1621	beta-fructofuranosidase activity
D073_RS17990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D073_RS17990	COG1263	PTS System
D073_RS17995	COG3711	transcriptional antiterminator
D073_RS18005	COG1404	Belongs to the peptidase S8 family
D073_RS18010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D073_RS18015	COG0778	Nitroreductase
D073_RS18020	COG0772	Belongs to the SEDS family
D073_RS18025	COG0454	-acetyltransferase
D073_RS18045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D073_RS18050	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D073_RS18055	COG2261	transglycosylase associated protein
D073_RS18060	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D073_RS18065	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D073_RS18070	COG2246	polysaccharide biosynthetic process
D073_RS18075	COG1309	transcriptional regulator
D073_RS18095	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D073_RS18100	COG2837	iron assimilation
D073_RS18105	COG2822	iron ion transport
D073_RS18120	COG0583	DNA-binding transcription factor activity
D073_RS18130	COG1346	cytolysis
D073_RS18135	COG4895	conserved protein (DUF2196)
D073_RS18140	COG0789	Transcriptional regulator
D073_RS18145	COG5504	Zn-dependent protease
D073_RS18150	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D073_RS18155	COG0346	lactoylglutathione lyase activity
D073_RS18160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D073_RS18165	COG1404	Belongs to the peptidase S8 family
D073_RS18170	COG1442	glycosyl transferase family 8
D073_RS18180	COG2357	RelA SpoT domain protein
D073_RS18185	COG1575	Belongs to the MenA family. Type 1 subfamily
D073_RS18210	COG1696	Membrane protein involved in D-alanine export
D073_RS18220	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D073_RS18225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D073_RS18230	COG1486	melibiose metabolic process
D073_RS18235	COG1447	Phosphotransferase system cellobiose-specific component IIA
D073_RS18240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D073_RS18245	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D073_RS18250	COG3711	transcriptional antiterminator
D073_RS18250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D073_RS18265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D073_RS18270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D073_RS18280	COG0640	Transcriptional regulator
D073_RS18285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D073_RS18290	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D073_RS18295	COG1447	Phosphotransferase system cellobiose-specific component IIA
D073_RS18300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D073_RS18305	COG2723	6-phospho-beta-galactosidase activity
D073_RS18310	COG1940	carbohydrate kinase activity
D073_RS18315	COG1482	cell wall glycoprotein biosynthetic process
D073_RS18325	COG0753	catalase activity
D073_RS18330	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D073_RS18335	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D073_RS18340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D073_RS18345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D073_RS18350	COG4988	ABC transporter
D073_RS18355	COG1294	oxidase, subunit
D073_RS18360	COG1271	oxidase subunit
D073_RS18365	COG3493	citrate carrier protein
D073_RS18370	COG0726	polysaccharide deacetylase
D073_RS18375	COG3842	ATPase activity
D073_RS18380	COG2508	Transcriptional regulator
D073_RS18385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D073_RS18395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D073_RS18405	COG4894	glucomannan catabolic process
D073_RS18410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D073_RS18415	COG0500	methyltransferase
D073_RS18420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D073_RS18435	COG0753	catalase activity
D073_RS18435	COG0693	protein deglycase activity
D073_RS18440	COG2851	Citrate transporter
D073_RS18445	COG2273	Hydrolase Family 16
D073_RS18450	COG3711	transcriptional antiterminator
D073_RS18455	COG2270	Major facilitator Superfamily
D073_RS18460	COG0513	Belongs to the DEAD box helicase family
D073_RS18555	COG0697	spore germination
D073_RS18560	COG0589	response to stress
D073_RS18565	COG2723	6-phospho-beta-galactosidase activity
D073_RS18570	COG2190	(PTS) system
D073_RS18570	COG1263	PTS System
D073_RS18570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D073_RS18585	COG0494	nUDIX hydrolase
D073_RS18590	COG3507	Belongs to the glycosyl hydrolase 43 family
D073_RS18615	COG0010	Belongs to the arginase family
D073_RS18620	COG0833	amino acid
D073_RS18625	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D073_RS18630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D073_RS18640	COG2390	Transcriptional regulator
D073_RS18645	COG0561	phosphatase activity
D073_RS18675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D073_RS18680	COG5294	Protein conserved in bacteria
D073_RS18685	COG0577	efflux transmembrane transporter activity
D073_RS18690	COG1136	(ABC) transporter
D073_RS18695	COG2205	protein histidine kinase activity
D073_RS18700	COG0745	RESPONSE REGULATOR receiver
D073_RS18715	COG1082	Xylose isomerase domain protein TIM barrel
D073_RS18725	COG2814	Major facilitator Superfamily
D073_RS18755	COG1349	DNA-binding transcription factor activity
D073_RS18760	COG0667	Aldo Keto reductase
D073_RS18765	COG2814	Major facilitator Superfamily
D073_RS18780	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS18785	COG2197	response regulator
D073_RS18790	COG4585	Histidine kinase
D073_RS18795	COG3239	Fatty acid desaturase
D073_RS18805	COG1309	transcriptional regulator
D073_RS18810	COG1012	belongs to the aldehyde dehydrogenase family
D073_RS18815	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D073_RS18825	COG0640	Transcriptional regulator
D073_RS18830	COG2814	Major facilitator Superfamily
D073_RS18835	COG1714	RDD family
D073_RS18845	COG0450	alkyl hydroperoxide reductase
D073_RS18850	COG3634	alkyl hydroperoxide reductase activity
D073_RS18855	COG3177	Filamentation induced by cAMP protein fic
D073_RS18860	COG1113	amino acid transport
D073_RS18870	COG2080	2 iron, 2 sulfur cluster binding
D073_RS18885	COG2068	MobA-Related Protein
D073_RS18890	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D073_RS18945	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D073_RS18950	COG0667	Aldo Keto reductase
D073_RS18955	COG0456	acetyltransferase
D073_RS18960	COG0457	Tetratricopeptide repeat
D073_RS18965	COG0010	Belongs to the arginase family
D073_RS18970	COG0833	amino acid
D073_RS18975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D073_RS18980	COG5658	integral membrane protein
D073_RS18985	COG0640	Transcriptional regulator
D073_RS18990	COG3829	transcription factor binding
D073_RS19000	COG0488	(ABC) transporter
D073_RS19015	COG5002	protein histidine kinase activity
D073_RS19020	COG0745	RESPONSE REGULATOR receiver
D073_RS19025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D073_RS19030	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D073_RS19035	COG4853	Protein conserved in bacteria
D073_RS19040	COG4863	YycH protein
D073_RS19045	COG5002	protein histidine kinase activity
D073_RS19050	COG0745	RESPONSE REGULATOR receiver
D073_RS19085	COG0346	lactoylglutathione lyase activity
D073_RS19090	COG0305	Participates in initiation and elongation during chromosome replication
D073_RS19110	COG3093	addiction module antidote protein HigA
D073_RS19115	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D073_RS19120	COG0297	glycogen (starch) synthase activity
D073_RS19130	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D073_RS19135	COG0438	transferase activity, transferring glycosyl groups
D073_RS19155	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D073_RS19160	COG4241	membrane
D073_RS19170	COG5577	PFAM Coat F domain
D073_RS19175	COG1733	regulation of RNA biosynthetic process
D073_RS19185	COG0697	spore germination
D073_RS19190	COG1621	beta-fructofuranosidase activity
D073_RS19195	COG1621	beta-fructofuranosidase activity
D073_RS19205	COG2318	DinB family
D073_RS19210	COG2211	Major facilitator Superfamily
D073_RS19215	COG0583	DNA-binding transcription factor activity
D073_RS19230	COG0778	Nitroreductase
D073_RS19235	COG1846	Transcriptional regulator
D073_RS19240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D073_RS19245	COG1846	Transcriptional regulator
D073_RS19250	COG2153	protein acetylation
D073_RS19260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D073_RS19265	COG0583	DNA-binding transcription factor activity
D073_RS19270	COG1028	Short-chain dehydrogenase reductase Sdr
D073_RS19275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D073_RS19280	COG0697	spore germination
D073_RS19285	COG1331	Highly conserved protein containing a thioredoxin domain
D073_RS19290	COG1266	CAAX protease self-immunity
D073_RS19295	COG2814	Major facilitator Superfamily
D073_RS19295	COG0477	Major facilitator Superfamily
D073_RS19300	COG0346	lactoylglutathione lyase activity
D073_RS19305	COG1609	Transcriptional regulator
D073_RS19310	COG0708	Exodeoxyribonuclease III
D073_RS19315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D073_RS19320	COG2169	Transcriptional regulator
D073_RS19330	COG0629	single-stranded DNA binding
D073_RS19340	COG0012	GTP binding
D073_RS19345	COG0243	molybdopterin cofactor binding
D073_RS19350	COG4481	Protein conserved in bacteria
D073_RS19355	COG3949	Membrane
D073_RS19370	COG1475	DNA binding
D073_RS19375	COG1192	Involved in chromosome partitioning
D073_RS19400	COG1847	R3H domain protein
D073_RS19405	COG0706	membrane insertase activity