locus-tag	class	description
LOC77_RS00010	COG0592	DNA-directed DNA polymerase activity
LOC77_RS00015	COG2501	S4 domain
LOC77_RS00030	COG0187	DNA topoisomerase II activity
LOC77_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LOC77_RS00070	COG0516	GMP reductase activity
LOC77_RS00070	COG0517	IMP dehydrogenase activity
LOC77_RS00075	COG1686	Belongs to the peptidase S11 family
LOC77_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
LOC77_RS00105	COG1428	Deoxynucleoside kinase
LOC77_RS00110	COG1428	Deoxynucleoside kinase
LOC77_RS00115	COG1388	LysM domain
LOC77_RS00115	COG3858	chitin binding
LOC77_RS00120	COG1335	isochorismatase
LOC77_RS00125	COG0590	tRNA wobble adenosine to inosine editing
LOC77_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LOC77_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LOC77_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
LOC77_RS00195	COG3853	Toxic anion resistance protein (TelA)
LOC77_RS00200	COG1982	Orn Lys Arg decarboxylase major
LOC77_RS00210	COG3870	Protein conserved in bacteria
LOC77_RS00215	COG1728	Protein conserved in bacteria
LOC77_RS00220	COG0470	DNA polymerase III
LOC77_RS00225	COG1774	PSP1 C-terminal conserved region
LOC77_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LOC77_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LOC77_RS00250	COG2002	toxin-antitoxin pair type II binding
LOC77_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LOC77_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LOC77_RS00260	COG0084	hydrolase, TatD family'
LOC77_RS00265	COG3583	domain protein
LOC77_RS00265	COG3584	3D domain protein
LOC77_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LOC77_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LOC77_RS00285	COG4466	Protein conserved in bacteria
LOC77_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LOC77_RS00305	COG0251	oxidation-reduction process
LOC77_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LOC77_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LOC77_RS00345	COG2002	toxin-antitoxin pair type II binding
LOC77_RS00350	COG2244	polysaccharide biosynthetic process
LOC77_RS00355	COG3956	TIGRFAM MazG family protein
LOC77_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LOC77_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LOC77_RS00380	COG1098	S1 RNA binding domain
LOC77_RS00395	COG2208	phosphoserine phosphatase activity
LOC77_RS00400	COG2304	oxidoreductase activity
LOC77_RS00405	COG0515	serine threonine protein kinase
LOC77_RS00410	COG0037	tRNA processing
LOC77_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LOC77_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LOC77_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LOC77_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LOC77_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LOC77_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
LOC77_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LOC77_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LOC77_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LOC77_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LOC77_RS00475	COG1396	sequence-specific DNA binding
LOC77_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LOC77_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LOC77_RS00565	COG4463	regulation of RNA biosynthetic process
LOC77_RS00570	COG3880	PFAM UvrB UvrC protein
LOC77_RS00580	COG0542	response to heat
LOC77_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LOC77_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LOC77_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
LOC77_RS00615	COG1045	serine acetyltransferase
LOC77_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LOC77_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LOC77_RS00635	COG3688	RNA-binding protein containing a PIN domain
LOC77_RS00640	COG1595	DNA-templated transcription, initiation
LOC77_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LOC77_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
LOC77_RS00680	COG2813	Specifically methylates the guanine in position
LOC77_RS00695	COG1358	cellular component organization or biogenesis
LOC77_RS00720	COG0596	Alpha beta hydrolase
LOC77_RS00830	COG0201	protein transport
LOC77_RS00840	COG0024	Methionine aminopeptidase
LOC77_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LOC77_RS00880	COG1122	ATPase activity
LOC77_RS00885	COG1122	ATPase activity
LOC77_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOC77_RS00910	COG2226	methyltransferase
LOC77_RS00915	COG2318	DinB family
LOC77_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
LOC77_RS00930	COG0489	protein tyrosine kinase activity
LOC77_RS00940	COG2194	sulfuric ester hydrolase activity
LOC77_RS00945	COG0726	polysaccharide deacetylase
LOC77_RS01005	COG0738	Major facilitator superfamily
LOC77_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LOC77_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
LOC77_RS01030	COG0385	Bile acid
LOC77_RS01035	COG2819	hydrolase of the alpha beta superfamily
LOC77_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOC77_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOC77_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LOC77_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LOC77_RS01055	COG2207	Transcriptional regulator
LOC77_RS01060	COG3876	Protein conserved in bacteria
LOC77_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
LOC77_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LOC77_RS01075	COG1263	PTS System
LOC77_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOC77_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LOC77_RS01090	COG1683	Conserved Protein
LOC77_RS01120	COG1595	DNA-templated transcription, initiation
LOC77_RS01125	COG5662	AntiSigma factor
LOC77_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LOC77_RS01135	COG4856	YbbR-like protein
LOC77_RS01175	COG1346	cytolysis
LOC77_RS01180	COG1380	Effector of murein hydrolase LrgA
LOC77_RS01185	COG1846	Transcriptional regulator
LOC77_RS01190	COG1113	amino acid transport
LOC77_RS01195	COG1011	Hydrolase
LOC77_RS01200	COG4585	Histidine kinase
LOC77_RS01205	COG2197	response regulator
LOC77_RS01210	COG1131	(ABC) transporter
LOC77_RS01250	COG0531	amino acid
LOC77_RS01255	COG0584	glycerophosphoryl diester phosphodiesterase
LOC77_RS01260	COG2271	Major facilitator Superfamily
LOC77_RS01270	COG2368	4-hydroxyphenylacetate
LOC77_RS01280	COG3409	Peptidoglycan-binding domain 1 protein
LOC77_RS01295	COG0371	Dehydrogenase
LOC77_RS01305	COG1183	phosphatidylcholine synthase activity
LOC77_RS01310	COG0586	Pfam SNARE associated Golgi protein
LOC77_RS01315	COG0688	phosphatidylethanolamine metabolic process
LOC77_RS01330	COG1301	dicarboxylic acid transport
LOC77_RS01335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LOC77_RS01340	COG0833	amino acid
LOC77_RS01345	COG2040	homocysteine
LOC77_RS01350	COG1115	amino acid carrier protein
LOC77_RS01355	COG2066	Belongs to the glutaminase family
LOC77_RS01360	COG4191	Histidine kinase
LOC77_RS01365	COG0784	Response regulator, receiver
LOC77_RS01370	COG3173	Aminoglycoside phosphotransferase
LOC77_RS01380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LOC77_RS01385	COG0778	Nitroreductase
LOC77_RS01390	COG0346	lactoylglutathione lyase activity
LOC77_RS01395	COG2259	Doxx family
LOC77_RS01400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LOC77_RS01415	COG3773	Cell wall hydrolase
LOC77_RS01420	COG3540	Alkaline phosphatase
LOC77_RS01425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LOC77_RS01430	COG0805	protein transport
LOC77_RS01440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LOC77_RS01445	COG0477	Major facilitator Superfamily
LOC77_RS01450	COG1309	transcriptional regulator
LOC77_RS01455	COG0252	asparaginase activity
LOC77_RS01460	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LOC77_RS01465	COG3012	SEC-C Motif Domain Protein
LOC77_RS01465	COG1405	negative regulation of cell septum assembly
LOC77_RS01470	COG0667	Aldo Keto reductase
LOC77_RS01485	COG1595	DNA-templated transcription, initiation
LOC77_RS01490	COG1876	peptidase activity
LOC77_RS01495	COG0457	Tetratricopeptide repeat
LOC77_RS01500	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS01505	COG0366	Alpha amylase catalytic
LOC77_RS01510	COG0803	Belongs to the bacterial solute-binding protein 9 family
LOC77_RS01515	COG1121	(ABC) transporter
LOC77_RS01520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LOC77_RS01525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOC77_RS01530	COG2310	stress, protein
LOC77_RS01535	COG2310	stress, protein
LOC77_RS01540	COG2310	stress, protein
LOC77_RS01545	COG0861	Integral membrane protein TerC family
LOC77_RS01555	COG3853	Toxic anion resistance protein (TelA)
LOC77_RS01560	COG0477	Major facilitator Superfamily
LOC77_RS01565	COG4175	Glycine betaine
LOC77_RS01565	COG0517	IMP dehydrogenase activity
LOC77_RS01570	COG4176	ABC-type proline glycine betaine transport system permease component
LOC77_RS01575	COG2113	Glycine betaine
LOC77_RS01580	COG1473	amidohydrolase
LOC77_RS01585	COG1288	antiporter activity
LOC77_RS01595	COG0366	Alpha amylase catalytic
LOC77_RS01605	COG2814	Major facilitator Superfamily
LOC77_RS01610	COG1846	Transcriptional regulator
LOC77_RS01615	COG1280	lysine exporter protein (LysE YggA)
LOC77_RS01620	COG3403	YqcI/YcgG family
LOC77_RS01625	COG1113	amino acid transport
LOC77_RS01630	COG3665	Urea carboxylase-associated protein
LOC77_RS01645	COG1660	Displays ATPase and GTPase activities
LOC77_RS01650	COG1082	Xylose isomerase domain protein TIM barrel
LOC77_RS01655	COG2271	Major facilitator Superfamily
LOC77_RS01660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LOC77_RS01665	COG3458	cephalosporin-C deacetylase activity
LOC77_RS01670	COG3541	Predicted nucleotidyltransferase
LOC77_RS01675	COG0506	proline dehydrogenase activity
LOC77_RS01680	COG1012	belongs to the aldehyde dehydrogenase family
LOC77_RS01685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOC77_RS01690	COG2508	Transcriptional regulator
LOC77_RS01700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LOC77_RS01700	COG1587	Uroporphyrinogen-III synthase
LOC77_RS01705	COG2146	nitrite reductase [NAD(P)H] activity
LOC77_RS01710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LOC77_RS01720	COG0523	cobalamin synthesis protein
LOC77_RS01725	COG1063	alcohol dehydrogenase
LOC77_RS01730	COG1714	RDD family
LOC77_RS01740	COG2723	6-phospho-beta-galactosidase activity
LOC77_RS01755	COG3209	COG3209 Rhs family protein
LOC77_RS01760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LOC77_RS01765	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LOC77_RS01770	COG1733	regulation of RNA biosynthetic process
LOC77_RS01775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS01795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS01805	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LOC77_RS01820	COG2364	Membrane
LOC77_RS01825	COG1126	abc transporter atp-binding protein
LOC77_RS01830	COG0765	amino acid transport
LOC77_RS01835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LOC77_RS01840	COG0583	DNA-binding transcription factor activity
LOC77_RS01845	COG0163	prenyltransferase activity
LOC77_RS01850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LOC77_RS01865	COG3104	oligopeptide transport
LOC77_RS01870	COG5434	Belongs to the glycosyl hydrolase 28 family
LOC77_RS01880	COG0697	spore germination
LOC77_RS01890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LOC77_RS01895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOC77_RS01900	COG0456	acetyltransferase
LOC77_RS01905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LOC77_RS01910	COG0765	amino acid transport
LOC77_RS01915	COG1126	abc transporter atp-binding protein
LOC77_RS01920	COG1473	amidohydrolase
LOC77_RS01925	COG2079	MmgE PrpD family protein
LOC77_RS01930	COG1136	(ABC) transporter
LOC77_RS01935	COG0577	efflux transmembrane transporter activity
LOC77_RS01940	COG0745	RESPONSE REGULATOR receiver
LOC77_RS01945	COG5002	protein histidine kinase activity
LOC77_RS01945	COG3850	Histidine kinase
LOC77_RS01950	COG0457	Tetratricopeptide repeat
LOC77_RS01965	COG0527	aspartate kinase activity
LOC77_RS01970	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOC77_RS01975	COG4605	iron ion homeostasis
LOC77_RS01980	COG4604	ABC transporter, ATP-binding protein
LOC77_RS01985	COG4607	ABC-type enterochelin transport system periplasmic component
LOC77_RS01990	COG2814	Major facilitator Superfamily
LOC77_RS01995	COG1309	transcriptional regulator
LOC77_RS02000	COG0778	Nitroreductase
LOC77_RS02005	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LOC77_RS02010	COG0640	Transcriptional regulator
LOC77_RS02015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LOC77_RS02020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LOC77_RS02025	COG1012	belongs to the aldehyde dehydrogenase family
LOC77_RS02030	COG4975	Glucose uptake
LOC77_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS02040	COG4549	nuclear export factor GLE1
LOC77_RS02045	COG1276	copper resistance
LOC77_RS02045	COG2372	response to copper ion
LOC77_RS02050	COG1349	DNA-binding transcription factor activity
LOC77_RS02060	COG2213	PTS system mannitol-specific
LOC77_RS02065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOC77_RS02075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LOC77_RS02085	COG0561	phosphatase activity
LOC77_RS02095	COG1914	H( )-stimulated, divalent metal cation uptake system
LOC77_RS02105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LOC77_RS02110	COG1984	allophanate hydrolase subunit 2
LOC77_RS02115	COG1414	Transcriptional regulator
LOC77_RS02120	COG2755	lipolytic protein G-D-S-L family
LOC77_RS02130	COG2329	Antibiotic biosynthesis monooxygenase
LOC77_RS02135	COG0768	penicillin binding
LOC77_RS02140	COG4989	oxidoreductase activity
LOC77_RS02145	COG3711	transcriptional antiterminator
LOC77_RS02150	COG0318	PFAM AMP-dependent synthetase and ligase
LOC77_RS02155	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS02160	COG1917	Cupin 2, conserved barrel domain protein
LOC77_RS02165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LOC77_RS02170	COG3871	stress protein (general stress protein 26)
LOC77_RS02180	COG2814	Major facilitator Superfamily
LOC77_RS02185	COG1522	sequence-specific DNA binding
LOC77_RS02190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LOC77_RS02190	COG0551	DNA topoisomerase type I activity
LOC77_RS02195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LOC77_RS02200	COG3706	GGDEF domain
LOC77_RS02205	COG5298	Protein conserved in bacteria
LOC77_RS02210	COG1215	transferase activity, transferring glycosyl groups
LOC77_RS02220	COG0531	amino acid
LOC77_RS02225	COG0494	nUDIX hydrolase
LOC77_RS02230	COG0028	Belongs to the TPP enzyme family
LOC77_RS02285	COG0457	Tetratricopeptide repeat
LOC77_RS02310	COG1914	H( )-stimulated, divalent metal cation uptake system
LOC77_RS02330	COG2076	Multidrug Resistance protein
LOC77_RS02335	COG2217	Heavy metal translocating P-type atpase
LOC77_RS02340	COG3729	General stress protein
LOC77_RS02345	COG0662	Cupin 2, conserved barrel domain protein
LOC77_RS02350	COG2329	Antibiotic biosynthesis monooxygenase
LOC77_RS02355	COG3546	catalase activity
LOC77_RS02360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LOC77_RS02365	COG3290	protein histidine kinase activity
LOC77_RS02370	COG4565	transcriptional regulatory protein
LOC77_RS02375	COG1301	dicarboxylic acid transport
LOC77_RS02380	COG0628	permease
LOC77_RS02385	COG1131	(ABC) transporter
LOC77_RS02390	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LOC77_RS02400	COG1960	acyl-CoA dehydrogenase activity
LOC77_RS02415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LOC77_RS02420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LOC77_RS02430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LOC77_RS02435	COG0513	Belongs to the DEAD box helicase family
LOC77_RS02440	COG3402	PFAM membrane-flanked domain
LOC77_RS02445	COG3428	Bacterial PH domain
LOC77_RS02450	COG0705	Rhomboid family
LOC77_RS02460	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LOC77_RS02465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LOC77_RS02470	COG0864	Transcriptional regulator
LOC77_RS02475	COG2337	Toxic component of a toxin-antitoxin (TA) module
LOC77_RS02480	COG1366	Belongs to the anti-sigma-factor antagonist family
LOC77_RS02485	COG1366	Belongs to the anti-sigma-factor antagonist family
LOC77_RS02490	COG2172	sigma factor antagonist activity
LOC77_RS02495	COG2208	phosphoserine phosphatase activity
LOC77_RS02500	COG1366	Belongs to the anti-sigma-factor antagonist family
LOC77_RS02510	COG1191	sigma factor activity
LOC77_RS02515	COG2208	phosphoserine phosphatase activity
LOC77_RS02520	COG2183	response to ionizing radiation
LOC77_RS02570	COG2249	NAD(P)H dehydrogenase (quinone) activity
LOC77_RS02590	COG0477	Major facilitator Superfamily
LOC77_RS02600	COG1764	response to oxidative stress
LOC77_RS02605	COG1846	Transcriptional regulator
LOC77_RS02615	COG1959	2 iron, 2 sulfur cluster binding
LOC77_RS02620	COG2910	NAD(P)H-binding
LOC77_RS02625	COG1278	Cold shock
LOC77_RS02630	COG1329	Transcriptional regulator
LOC77_RS02635	COG1937	Protein conserved in bacteria
LOC77_RS02640	COG2210	Belongs to the sulfur carrier protein TusA family
LOC77_RS02645	COG1054	Belongs to the UPF0176 family
LOC77_RS02650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LOC77_RS02650	COG0425	Belongs to the sulfur carrier protein TusA family
LOC77_RS02660	COG0425	Belongs to the sulfur carrier protein TusA family
LOC77_RS02665	COG0730	response to heat
LOC77_RS02675	COG1794	racemase activity, acting on amino acids and derivatives
LOC77_RS02690	COG3621	Patatin-like phospholipase
LOC77_RS02715	COG0277	FAD linked oxidase domain protein
LOC77_RS02760	COG1064	alcohol dehydrogenase
LOC77_RS02765	COG0789	Transcriptional regulator
LOC77_RS02775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LOC77_RS02790	COG2814	Major facilitator Superfamily
LOC77_RS02795	COG1309	transcriptional regulator
LOC77_RS02800	COG5577	PFAM Coat F domain
LOC77_RS02810	COG1063	alcohol dehydrogenase
LOC77_RS02815	COG5577	PFAM Coat F domain
LOC77_RS02825	COG4585	Histidine kinase
LOC77_RS02830	COG2197	response regulator
LOC77_RS02835	COG2409	Drug exporters of the RND superfamily
LOC77_RS02840	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LOC77_RS02845	COG0488	(ABC) transporter
LOC77_RS02850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LOC77_RS02855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOC77_RS02865	COG2814	Major facilitator Superfamily
LOC77_RS02870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LOC77_RS02880	COG0730	response to heat
LOC77_RS02885	COG0456	acetyltransferase
LOC77_RS02890	COG4978	Transcriptional regulator
LOC77_RS02890	COG0789	Transcriptional regulator
LOC77_RS02895	COG0697	spore germination
LOC77_RS02900	COG1051	belongs to the nudix hydrolase family
LOC77_RS02905	COG2226	methyltransferase
LOC77_RS02925	COG1802	Transcriptional regulator
LOC77_RS02930	COG1819	glycosyl
LOC77_RS02955	COG1388	LysM domain
LOC77_RS02960	COG2814	Major facilitator Superfamily
LOC77_RS02965	COG2188	Transcriptional regulator
LOC77_RS02970	COG2186	Transcriptional regulator
LOC77_RS02975	COG2807	transmembrane transport
LOC77_RS02980	COG2076	Multidrug Resistance protein
LOC77_RS02985	COG2076	Multidrug Resistance protein
LOC77_RS02990	COG1309	transcriptional regulator
LOC77_RS02995	COG0531	amino acid
LOC77_RS03005	COG3832	glyoxalase III activity
LOC77_RS03010	COG0604	alcohol dehydrogenase
LOC77_RS03015	COG2814	Major facilitator Superfamily
LOC77_RS03055	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LOC77_RS03060	COG0802	atpase or kinase
LOC77_RS03065	COG1214	PFAM Peptidase M22, glycoprotease
LOC77_RS03070	COG0456	acetyltransferase
LOC77_RS03075	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LOC77_RS03080	COG0488	(ABC) transporter
LOC77_RS03095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LOC77_RS03100	COG0805	protein transport
LOC77_RS03110	COG1266	CAAX protease self-immunity
LOC77_RS03170	COG1131	(ABC) transporter
LOC77_RS03175	COG0842	Transport permease protein
LOC77_RS03180	COG0457	Tetratricopeptide repeat
LOC77_RS03185	COG1063	alcohol dehydrogenase
LOC77_RS03190	COG2211	Major facilitator Superfamily
LOC77_RS03195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LOC77_RS03205	COG1842	Phage shock protein A
LOC77_RS03210	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LOC77_RS03215	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LOC77_RS03220	COG4260	virion core protein, lumpy skin disease virus
LOC77_RS03225	COG2755	lipolytic protein G-D-S-L family
LOC77_RS03225	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LOC77_RS03235	COG1595	DNA-templated transcription, initiation
LOC77_RS03240	COG1063	alcohol dehydrogenase
LOC77_RS03245	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LOC77_RS03250	COG0823	Involved in the tonB-independent uptake of proteins
LOC77_RS03265	COG2132	Multicopper oxidase
LOC77_RS03270	COG1113	amino acid transport
LOC77_RS03275	COG0714	Associated with various cellular activities
LOC77_RS03280	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LOC77_RS03285	COG1305	Transglutaminase-like
LOC77_RS03305	COG2252	PERMEase
LOC77_RS03310	COG3064	Membrane
LOC77_RS03330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LOC77_RS03335	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LOC77_RS03340	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LOC77_RS03345	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LOC77_RS03350	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LOC77_RS03365	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LOC77_RS03375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LOC77_RS03380	COG0138	bifunctional purine biosynthesis protein purh
LOC77_RS03385	COG0151	Belongs to the GarS family
LOC77_RS03395	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LOC77_RS03400	COG1470	cell adhesion involved in biofilm formation
LOC77_RS03405	COG4496	protein, YerC YecD
LOC77_RS03410	COG0069	glutamate synthase activity
LOC77_RS03420	COG0210	DNA helicase
LOC77_RS03430	COG4851	CamS sex pheromone cAM373 precursor
LOC77_RS03435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LOC77_RS03440	COG1285	pathogenesis
LOC77_RS03445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOC77_RS03465	COG1309	transcriptional regulator
LOC77_RS03470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LOC77_RS03475	COG1597	lipid kinase activity
LOC77_RS03480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LOC77_RS03490	COG1131	(ABC) transporter
LOC77_RS03525	COG5444	nuclease activity
LOC77_RS03560	COG3546	catalase activity
LOC77_RS03565	COG0454	-acetyltransferase
LOC77_RS03575	COG2323	membrane
LOC77_RS03585	COG0346	lactoylglutathione lyase activity
LOC77_RS03590	COG1366	Belongs to the anti-sigma-factor antagonist family
LOC77_RS03595	COG5583	Uncharacterized small protein (DUF2292)
LOC77_RS03600	COG0196	riboflavin kinase activity
LOC77_RS03605	COG0670	Belongs to the BI1 family
LOC77_RS03615	COG1846	Transcriptional regulator
LOC77_RS03620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LOC77_RS03630	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LOC77_RS03630	COG2124	cytochrome p450
LOC77_RS03645	COG1131	(ABC) transporter
LOC77_RS03690	COG4106	trans-aconitate 2-methyltransferase activity
LOC77_RS03695	COG1368	sulfuric ester hydrolase activity
LOC77_RS03700	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LOC77_RS03705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LOC77_RS03710	COG1442	glycosyl transferase family 8
LOC77_RS03715	COG1216	Glycosyl transferase, family 2
LOC77_RS03720	COG1442	glycosyl transferase family 8
LOC77_RS03725	COG2223	nitrite transmembrane transporter activity
LOC77_RS03730	COG0531	amino acid
LOC77_RS03735	COG1012	belongs to the aldehyde dehydrogenase family
LOC77_RS03740	COG0840	transmembrane signaling receptor activity
LOC77_RS03745	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS03750	COG0463	Glycosyl transferase, family 2
LOC77_RS03750	COG0457	Tetratricopeptide repeat
LOC77_RS03755	COG0488	(ABC) transporter
LOC77_RS03760	COG0789	Transcriptional regulator
LOC77_RS03765	COG2814	Major facilitator Superfamily
LOC77_RS03770	COG0488	(ABC) transporter
LOC77_RS03775	COG0513	Belongs to the DEAD box helicase family
LOC77_RS03785	COG2130	NADP-dependent
LOC77_RS03800	COG3866	Pectate lyase
LOC77_RS03805	COG0471	metal ion transport
LOC77_RS03830	COG0745	RESPONSE REGULATOR receiver
LOC77_RS03830	COG2972	Histidine kinase
LOC77_RS03840	COG3279	Response regulator of the LytR AlgR family
LOC77_RS03850	COG3764	Sortase (surface protein transpeptidase)
LOC77_RS03855	COG3290	protein histidine kinase activity
LOC77_RS03860	COG4565	transcriptional regulatory protein
LOC77_RS03865	COG3181	Tripartite tricarboxylate transporter family receptor
LOC77_RS03870	COG2851	Citrate transporter
LOC77_RS03875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LOC77_RS03880	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LOC77_RS03890	COG2258	MOSC domain
LOC77_RS03910	COG0024	Methionine aminopeptidase
LOC77_RS03915	COG1263	PTS System
LOC77_RS03915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOC77_RS03925	COG1368	sulfuric ester hydrolase activity
LOC77_RS03935	COG0071	Belongs to the small heat shock protein (HSP20) family
LOC77_RS03950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOC77_RS03950	COG1263	PTS System
LOC77_RS03955	COG0366	Alpha amylase catalytic
LOC77_RS03960	COG2188	Transcriptional regulator
LOC77_RS03965	COG0778	Nitroreductase
LOC77_RS03980	COG0737	Belongs to the 5'-nucleotidase family
LOC77_RS03985	COG0693	protein deglycase activity
LOC77_RS03990	COG1609	Transcriptional regulator
LOC77_RS04005	COG2814	Major facilitator Superfamily
LOC77_RS04015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LOC77_RS04020	COG4980	gas vesicle protein
LOC77_RS04025	COG1295	ribonuclease BN
LOC77_RS04030	COG0477	Major facilitator Superfamily
LOC77_RS04035	COG0387	Pfam Sodium calcium exchanger
LOC77_RS04045	COG0668	transmembrane transport
LOC77_RS04050	COG0535	radical SAM domain protein
LOC77_RS04060	COG0726	polysaccharide deacetylase
LOC77_RS04065	COG2084	Dehydrogenase
LOC77_RS04075	COG0598	Magnesium transport protein CorA
LOC77_RS04080	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LOC77_RS04085	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LOC77_RS04110	COG1131	(ABC) transporter
LOC77_RS04120	COG1131	(ABC) transporter
LOC77_RS04125	COG1668	transmembrane transport
LOC77_RS04140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LOC77_RS04145	COG4637	Psort location Cytoplasmic, score
LOC77_RS04150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LOC77_RS04155	COG0022	dehydrogenase e1 component
LOC77_RS04160	COG0508	dehydrogenase complex catalyzes the overall conversion of
LOC77_RS04165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LOC77_RS04170	COG3284	Transcriptional regulator
LOC77_RS04180	COG1486	melibiose metabolic process
LOC77_RS04185	COG1737	Transcriptional regulator
LOC77_RS04190	COG1263	PTS System
LOC77_RS04190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOC77_RS04195	COG1132	(ABC) transporter
LOC77_RS04200	COG1132	(ABC) transporter
LOC77_RS04205	COG2259	Doxx family
LOC77_RS04210	COG2514	catechol 2,3-dioxygenase activity
LOC77_RS04220	COG1695	Transcriptional regulator
LOC77_RS04225	COG2249	NAD(P)H dehydrogenase (quinone) activity
LOC77_RS04230	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LOC77_RS04235	COG0574	Belongs to the PEP-utilizing enzyme family
LOC77_RS04235	COG3848	Pyruvate phosphate dikinase
LOC77_RS04240	COG2732	(Barnase) inhibitor
LOC77_RS04245	COG2318	DinB family
LOC77_RS04250	COG2814	Major facilitator Superfamily
LOC77_RS04255	COG1846	Transcriptional regulator
LOC77_RS04260	COG0392	lysyltransferase activity
LOC77_RS04260	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LOC77_RS04265	COG0384	phenazine biosynthesis protein PhzF
LOC77_RS04270	COG0778	Nitroreductase
LOC77_RS04285	COG1090	epimerase
LOC77_RS04300	COG2814	Major facilitator Superfamily
LOC77_RS04310	COG3591	Belongs to the peptidase S1B family
LOC77_RS04325	COG3103	Sh3 type 3 domain protein
LOC77_RS04330	COG5658	integral membrane protein
LOC77_RS04335	COG0596	Alpha beta hydrolase
LOC77_RS04340	COG0463	Glycosyl transferase, family 2
LOC77_RS04345	COG4485	Bacterial membrane protein, YfhO
LOC77_RS04350	COG1988	membrane-bound metal-dependent
LOC77_RS04355	COG1194	a g-specific adenine glycosylase
LOC77_RS04365	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS04385	COG1132	(ABC) transporter
LOC77_RS04390	COG4129	membrane
LOC77_RS04400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LOC77_RS04405	COG0735	belongs to the Fur family
LOC77_RS04515	COG3340	Belongs to the peptidase S51 family
LOC77_RS04525	COG0277	FAD linked oxidase domain protein
LOC77_RS04535	COG0747	negative chemotaxis
LOC77_RS04540	COG0601	transmembrane transport
LOC77_RS04545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOC77_RS04550	COG0444	Belongs to the ABC transporter superfamily
LOC77_RS04555	COG4608	Belongs to the ABC transporter superfamily
LOC77_RS04560	COG0753	catalase activity
LOC77_RS04570	COG1116	anion transmembrane transporter activity
LOC77_RS04575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LOC77_RS04580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LOC77_RS04600	COG1476	TRANSCRIPTIONal
LOC77_RS04610	COG3382	B3 4 domain protein
LOC77_RS04615	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LOC77_RS04625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LOC77_RS04630	COG0789	Transcriptional regulator
LOC77_RS04635	COG1664	Polymer-forming cytoskeletal
LOC77_RS04640	COG1664	Polymer-forming cytoskeletal
LOC77_RS04645	COG2766	serine protein kinase
LOC77_RS04655	COG1846	Transcriptional regulator
LOC77_RS04660	COG1566	PFAM secretion protein HlyD family protein
LOC77_RS04665	COG2814	Major facilitator Superfamily
LOC77_RS04670	COG0655	NAD(P)H dehydrogenase (quinone) activity
LOC77_RS04685	COG1725	Transcriptional regulator
LOC77_RS04690	COG1131	(ABC) transporter
LOC77_RS04695	COG1131	(ABC) transporter
LOC77_RS04700	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LOC77_RS04705	COG1278	Cold shock
LOC77_RS04710	COG1464	Belongs to the NlpA lipoprotein family
LOC77_RS04715	COG3706	GGDEF domain
LOC77_RS04720	COG1823	symporter activity
LOC77_RS04740	COG5577	PFAM Coat F domain
LOC77_RS04745	COG4085	toxin activity
LOC77_RS04745	COG1525	nuclease
LOC77_RS04745	COG0737	Belongs to the 5'-nucleotidase family
LOC77_RS04750	COG3764	Sortase (surface protein transpeptidase)
LOC77_RS04755	COG0564	pseudouridine synthase activity
LOC77_RS04765	COG0517	IMP dehydrogenase activity
LOC77_RS04770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LOC77_RS04775	COG3153	acetyltransferase
LOC77_RS04775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LOC77_RS04780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LOC77_RS04785	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LOC77_RS04790	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LOC77_RS04800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LOC77_RS04805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LOC77_RS04810	COG4585	Histidine kinase
LOC77_RS04810	COG2203	Gaf domain
LOC77_RS04815	COG2197	response regulator
LOC77_RS04820	COG0431	NADPH-dependent FMN reductase
LOC77_RS04835	COG0791	NLP P60 protein
LOC77_RS04835	COG1388	LysM domain
LOC77_RS04840	COG1959	2 iron, 2 sulfur cluster binding
LOC77_RS04850	COG2719	SpoVR family
LOC77_RS04855	COG1785	Belongs to the alkaline phosphatase family
LOC77_RS04860	COG0791	NLP P60 protein
LOC77_RS04860	COG1388	LysM domain
LOC77_RS04865	COG0583	DNA-binding transcription factor activity
LOC77_RS04870	COG0372	Belongs to the citrate synthase family
LOC77_RS04875	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS04880	COG0531	amino acid
LOC77_RS04885	COG0733	neurotransmitter:sodium symporter activity
LOC77_RS04900	COG1595	DNA-templated transcription, initiation
LOC77_RS04905	COG0204	Acyl-transferase
LOC77_RS04910	COG1253	flavin adenine dinucleotide binding
LOC77_RS04915	COG0789	Transcriptional regulator
LOC77_RS04920	COG0436	Aminotransferase
LOC77_RS04925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LOC77_RS04930	COG1253	flavin adenine dinucleotide binding
LOC77_RS04935	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LOC77_RS04940	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LOC77_RS04945	COG0584	glycerophosphoryl diester phosphodiesterase
LOC77_RS04955	COG0668	transmembrane transport
LOC77_RS04960	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LOC77_RS04965	COG0726	polysaccharide deacetylase
LOC77_RS04970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LOC77_RS04975	COG3226	Transcriptional regulator
LOC77_RS04985	COG0589	response to stress
LOC77_RS04990	COG1132	(ABC) transporter
LOC77_RS04995	COG1132	(ABC) transporter
LOC77_RS05000	COG0702	epimerase
LOC77_RS05020	COG0189	ligase activity
LOC77_RS05025	COG0189	ligase activity
LOC77_RS05040	COG4335	DNA alkylation repair
LOC77_RS05045	COG0561	phosphatase activity
LOC77_RS05050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LOC77_RS05060	COG0475	glutathione-regulated potassium exporter activity
LOC77_RS05065	COG0490	domain, Protein
LOC77_RS05075	COG1024	Enoyl-CoA hydratase
LOC77_RS05085	COG4152	abc transporter atp-binding protein
LOC77_RS05090	COG1668	transmembrane transport
LOC77_RS05095	COG0420	3'-5' exonuclease activity
LOC77_RS05100	COG4717	serine-type aminopeptidase activity
LOC77_RS05115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LOC77_RS05150	COG4980	gas vesicle protein
LOC77_RS05165	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LOC77_RS05170	COG0537	adenosine 5'-monophosphoramidase activity
LOC77_RS05175	COG1131	(ABC) transporter
LOC77_RS05180	COG4473	ABC transporter
LOC77_RS05190	COG1473	amidohydrolase
LOC77_RS05195	COG3069	C4-dicarboxylate transmembrane transporter activity
LOC77_RS05200	COG2329	Antibiotic biosynthesis monooxygenase
LOC77_RS05205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LOC77_RS05215	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LOC77_RS05220	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LOC77_RS05225	COG1309	transcriptional regulator
LOC77_RS05230	COG1511	domain protein
LOC77_RS05235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LOC77_RS05245	COG1363	Peptidase, m42
LOC77_RS05250	COG1301	dicarboxylic acid transport
LOC77_RS05260	COG1234	tRNA 3'-trailer cleavage
LOC77_RS05265	COG0095	Lipoate-protein ligase
LOC77_RS05270	COG0702	epimerase
LOC77_RS05275	COG0318	PFAM AMP-dependent synthetase and ligase
LOC77_RS05285	COG0501	Belongs to the peptidase M48B family
LOC77_RS05290	COG1404	Belongs to the peptidase S8 family
LOC77_RS05295	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LOC77_RS05300	COG0406	alpha-ribazole phosphatase activity
LOC77_RS05305	COG0183	Belongs to the thiolase family
LOC77_RS05310	COG0318	PFAM AMP-dependent synthetase and ligase
LOC77_RS05315	COG1268	BioY protein
LOC77_RS05320	COG0840	transmembrane signaling receptor activity
LOC77_RS05325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LOC77_RS05325	COG0723	plastoquinol--plastocyanin reductase activity
LOC77_RS05330	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS05340	COG4903	ComK protein
LOC77_RS05350	COG5646	InterPro IPR014922
LOC77_RS05370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOC77_RS05385	COG0398	Pfam SNARE associated Golgi protein
LOC77_RS05390	COG0681	Belongs to the peptidase S26 family
LOC77_RS05395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LOC77_RS05400	COG1846	Transcriptional regulator
LOC77_RS05405	COG3180	Ammonia monooxygenase
LOC77_RS05410	COG2814	Major facilitator Superfamily
LOC77_RS05420	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LOC77_RS05425	COG2323	membrane
LOC77_RS05440	COG0420	3'-5' exonuclease activity
LOC77_RS05445	COG0419	ATPase involved in DNA repair
LOC77_RS05450	COG1403	HNH endonuclease
LOC77_RS05490	COG0179	Fumarylacetoacetate (FAA) hydrolase
LOC77_RS05505	COG0367	asparagine synthase
LOC77_RS05510	COG1562	ergosterol biosynthetic process
LOC77_RS05515	COG0534	Mate efflux family protein
LOC77_RS05520	COG2207	Transcriptional regulator
LOC77_RS05520	COG1917	Cupin 2, conserved barrel domain protein
LOC77_RS05525	COG1609	Transcriptional regulator
LOC77_RS05530	COG0673	inositol 2-dehydrogenase activity
LOC77_RS05535	COG2318	DinB family
LOC77_RS05540	COG1357	PFAM Pentapeptide repeats (8 copies)
LOC77_RS05545	COG2153	protein acetylation
LOC77_RS05550	COG0646	methionine synthase
LOC77_RS05550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LOC77_RS05560	COG2996	Protein conserved in bacteria
LOC77_RS05565	COG1744	ABC transporter substrate-binding protein PnrA-like
LOC77_RS05570	COG0840	transmembrane signaling receptor activity
LOC77_RS05580	COG1307	EDD domain protein, DegV family
LOC77_RS05585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOC77_RS05605	COG0561	phosphatase activity
LOC77_RS05610	COG1073	alpha beta
LOC77_RS05615	COG2151	metal-sulfur cluster biosynthetic enzyme
LOC77_RS05625	COG0277	FAD linked oxidase domain protein
LOC77_RS05630	COG2271	Major facilitator Superfamily
LOC77_RS05640	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LOC77_RS05650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LOC77_RS05655	COG0505	Belongs to the CarA family
LOC77_RS05660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LOC77_RS05665	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LOC77_RS05680	COG2267	carboxylic ester hydrolase activity
LOC77_RS05690	COG1744	ABC transporter substrate-binding protein PnrA-like
LOC77_RS05705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LOC77_RS05710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LOC77_RS05715	COG5504	Zn-dependent protease
LOC77_RS05720	COG0444	Belongs to the ABC transporter superfamily
LOC77_RS05725	COG4608	Belongs to the ABC transporter superfamily
LOC77_RS05735	COG0601	transmembrane transport
LOC77_RS05740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOC77_RS05760	COG0180	Tryptophanyl-tRNA synthetase
LOC77_RS05765	COG4166	transmembrane transport
LOC77_RS05770	COG0601	transmembrane transport
LOC77_RS05775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOC77_RS05780	COG0444	Belongs to the ABC transporter superfamily
LOC77_RS05785	COG4608	Belongs to the ABC transporter superfamily
LOC77_RS05795	COG0456	acetyltransferase
LOC77_RS05800	COG1393	Belongs to the ArsC family
LOC77_RS05805	COG0861	Integral membrane protein TerC family
LOC77_RS05815	COG4862	establishment of competence for transformation
LOC77_RS05820	COG4469	Competence protein
LOC77_RS05825	COG1164	Oligoendopeptidase f
LOC77_RS05835	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LOC77_RS05840	COG2346	COG2346, Truncated hemoglobins
LOC77_RS05845	COG0741	lytic transglycosylase activity
LOC77_RS05850	COG4116	CYTH
LOC77_RS05860	COG2357	RelA SpoT domain protein
LOC77_RS05865	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LOC77_RS05870	COG0564	pseudouridine synthase activity
LOC77_RS05880	COG0569	domain protein
LOC77_RS05880	COG0475	glutathione-regulated potassium exporter activity
LOC77_RS05885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LOC77_RS05890	COG0352	thiamine-phosphate diphosphorylase activity
LOC77_RS05895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LOC77_RS05900	COG2104	thiamine diphosphate biosynthetic process
LOC77_RS05910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LOC77_RS05915	COG0351	phosphomethylpyrimidine kinase
LOC77_RS05920	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LOC77_RS05975	COG0210	DNA helicase
LOC77_RS05995	COG1131	(ABC) transporter
LOC77_RS06005	COG2153	protein acetylation
LOC77_RS06015	COG2382	esterase
LOC77_RS06020	COG0626	cystathionine gamma-synthase activity
LOC77_RS06025	COG0626	cystathionine gamma-synthase activity
LOC77_RS06060	COG5444	nuclease activity
LOC77_RS06070	COG0346	lactoylglutathione lyase activity
LOC77_RS06075	COG2367	Beta-lactamase
LOC77_RS06080	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LOC77_RS06090	COG1846	Transcriptional regulator
LOC77_RS06100	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LOC77_RS06105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LOC77_RS06110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LOC77_RS06115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOC77_RS06115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOC77_RS06120	COG1447	Phosphotransferase system cellobiose-specific component IIA
LOC77_RS06130	COG1349	DNA-binding transcription factor activity
LOC77_RS06145	COG1285	pathogenesis
LOC77_RS06155	COG2205	protein histidine kinase activity
LOC77_RS06165	COG3383	formate dehydrogenase (NAD+) activity
LOC77_RS06170	COG2427	Protein of unknown function (DUF1641)
LOC77_RS06175	COG2124	cytochrome p450
LOC77_RS06180	COG1819	glycosyl
LOC77_RS06190	COG1587	Uroporphyrinogen-III synthase
LOC77_RS06195	COG0390	transport system, permease component
LOC77_RS06200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LOC77_RS06205	COG0697	spore germination
LOC77_RS06210	COG4297	protein containing double-stranded beta helix domain
LOC77_RS06220	COG1252	NADH dehydrogenase
LOC77_RS06230	COG2211	Major facilitator Superfamily
LOC77_RS06235	COG1609	Transcriptional regulator
LOC77_RS06240	COG0246	Mannitol dehydrogenase
LOC77_RS06245	COG2721	sulfolactate sulfo-lyase activity
LOC77_RS06250	COG0745	RESPONSE REGULATOR receiver
LOC77_RS06255	COG2770	Histidine kinase
LOC77_RS06255	COG2205	protein histidine kinase activity
LOC77_RS06260	COG1121	(ABC) transporter
LOC77_RS06270	COG0730	response to heat
LOC77_RS06275	COG2318	DinB family
LOC77_RS06280	COG0457	Tetratricopeptide repeat
LOC77_RS06290	COG1388	LysM domain
LOC77_RS06290	COG3409	Peptidoglycan-binding domain 1 protein
LOC77_RS06290	COG5632	N-Acetylmuramoyl-L-alanine amidase
LOC77_RS06300	COG4195	phage-related replication protein
LOC77_RS06310	COG2856	Zn peptidase
LOC77_RS06315	COG1396	sequence-specific DNA binding
LOC77_RS06325	COG1522	sequence-specific DNA binding
LOC77_RS06330	COG1484	DNA-dependent DNA replication
LOC77_RS06350	COG1595	DNA-templated transcription, initiation
LOC77_RS06355	COG3728	DNA packaging
LOC77_RS06355	COG5484	DNA packaging
LOC77_RS06360	COG1783	phage Terminase large subunit
LOC77_RS06365	COG5518	Phage portal protein
LOC77_RS06370	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LOC77_RS06375	COG4653	Phage capsid family
LOC77_RS06425	COG5412	phage tail tape measure protein
LOC77_RS06425	COG5412	phage tail tape measure protein
LOC77_RS06425	COG3953	SLT domain
LOC77_RS06425	COG5412	phage tail tape measure protein
LOC77_RS06425	COG3953	SLT domain
LOC77_RS06425	COG3953	SLT domain
LOC77_RS06430	COG1652	LysM domain
LOC77_RS06435	COG4193	domain, Protein
LOC77_RS06445	COG3628	GPW Gp25 family protein
LOC77_RS06450	COG3299	homolog of phage Mu protein gp47
LOC77_RS06455	COG3778	Protein conserved in bacteria
LOC77_RS06495	COG5632	N-Acetylmuramoyl-L-alanine amidase
LOC77_RS06495	COG3409	Peptidoglycan-binding domain 1 protein
LOC77_RS06515	COG0306	phosphate transporter
LOC77_RS06520	COG1392	Phosphate transport regulator
LOC77_RS06525	COG0531	amino acid
LOC77_RS06530	COG0346	lactoylglutathione lyase activity
LOC77_RS06535	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LOC77_RS06540	COG0463	Glycosyl transferase, family 2
LOC77_RS06550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOC77_RS06555	COG0477	Major facilitator Superfamily
LOC77_RS06560	COG2362	D-Aminopeptidase
LOC77_RS06565	COG0601	transmembrane transport
LOC77_RS06570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOC77_RS06575	COG0444	Belongs to the ABC transporter superfamily
LOC77_RS06580	COG4166	transmembrane transport
LOC77_RS06585	COG1619	proteins homologs of microcin C7 resistance protein MccF
LOC77_RS06590	COG4948	Mandelate Racemase Muconate Lactonizing
LOC77_RS06595	COG0791	NLP P60 protein
LOC77_RS06600	COG4608	Belongs to the ABC transporter superfamily
LOC77_RS06605	COG2706	6-phosphogluconolactonase activity
LOC77_RS06610	COG1834	amidinotransferase
LOC77_RS06615	COG1607	acyl-coa hydrolase
LOC77_RS06620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LOC77_RS06625	COG2076	Multidrug Resistance protein
LOC77_RS06630	COG2076	Multidrug Resistance protein
LOC77_RS06635	COG0788	formyltetrahydrofolate deformylase activity
LOC77_RS06640	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LOC77_RS06650	COG1764	response to oxidative stress
LOC77_RS06655	COG1846	Transcriptional regulator
LOC77_RS06660	COG1764	response to oxidative stress
LOC77_RS06675	COG0457	Tetratricopeptide repeat
LOC77_RS06675	COG0463	Glycosyl transferase, family 2
LOC77_RS06685	COG2814	Major facilitator Superfamily
LOC77_RS06690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LOC77_RS06700	COG1404	Belongs to the peptidase S8 family
LOC77_RS06705	COG1366	Belongs to the anti-sigma-factor antagonist family
LOC77_RS06710	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOC77_RS06715	COG1122	ATPase activity
LOC77_RS06720	COG4721	ABC-type cobalt transport system, permease component
LOC77_RS06725	COG1388	LysM domain
LOC77_RS06725	COG3858	chitin binding
LOC77_RS06735	COG2239	Acts as a magnesium transporter
LOC77_RS06740	COG0789	Transcriptional regulator
LOC77_RS06755	COG1846	Transcriptional regulator
LOC77_RS06760	COG0726	polysaccharide deacetylase
LOC77_RS06765	COG1793	dna ligase
LOC77_RS06765	COG3285	dna ligase
LOC77_RS06770	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LOC77_RS06775	COG0586	Pfam SNARE associated Golgi protein
LOC77_RS06785	COG1191	sigma factor activity
LOC77_RS06810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LOC77_RS06815	COG2323	membrane
LOC77_RS06825	COG3594	Acyltransferase
LOC77_RS06830	COG5002	protein histidine kinase activity
LOC77_RS06835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LOC77_RS06855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LOC77_RS06860	COG0436	Aminotransferase
LOC77_RS06890	COG3852	Histidine kinase
LOC77_RS06895	COG1846	Transcriptional regulator
LOC77_RS06900	COG1360	Flagellar Motor Protein
LOC77_RS06905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LOC77_RS06910	COG0542	response to heat
LOC77_RS06915	COG3949	Membrane
LOC77_RS06930	COG0720	synthase
LOC77_RS06935	COG0602	queuosine metabolic process
LOC77_RS06950	COG4873	Protein conserved in bacteria
LOC77_RS06960	COG3773	Cell wall hydrolase
LOC77_RS06965	COG2244	polysaccharide biosynthetic process
LOC77_RS06970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LOC77_RS06975	COG2217	Heavy metal translocating P-type atpase
LOC77_RS06980	COG0006	proline dipeptidase activity
LOC77_RS06985	COG1609	Transcriptional regulator
LOC77_RS06990	COG3711	transcriptional antiterminator
LOC77_RS06995	COG2190	(PTS) system
LOC77_RS06995	COG1263	PTS System
LOC77_RS06995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOC77_RS07000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOC77_RS07005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LOC77_RS07015	COG1533	DNA photolyase activity
LOC77_RS07020	COG0840	transmembrane signaling receptor activity
LOC77_RS07025	COG2084	Dehydrogenase
LOC77_RS07030	COG2340	Cysteine-rich secretory protein family
LOC77_RS07035	COG0768	penicillin binding
LOC77_RS07040	COG4191	Histidine kinase
LOC77_RS07045	COG0436	Aminotransferase
LOC77_RS07055	COG0784	Response regulator, receiver
LOC77_RS07055	COG0835	chemotaxis
LOC77_RS07065	COG2814	Major facilitator Superfamily
LOC77_RS07070	COG1376	ErfK ybiS ycfS ynhG family protein
LOC77_RS07075	COG1408	metallophosphoesterase
LOC77_RS07080	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS07090	COG2200	EAL domain
LOC77_RS07095	COG4703	Protein of unknown function (DUF1797)
LOC77_RS07100	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LOC77_RS07110	COG0517	IMP dehydrogenase activity
LOC77_RS07115	COG0583	DNA-binding transcription factor activity
LOC77_RS07120	COG0716	FMN binding
LOC77_RS07130	COG0716	FMN binding
LOC77_RS07150	COG0668	transmembrane transport
LOC77_RS07155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LOC77_RS07175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LOC77_RS07180	COG0303	'Molybdopterin
LOC77_RS07185	COG1763	Mo-molybdopterin cofactor biosynthetic process
LOC77_RS07190	COG0314	molybdopterin synthase activity
LOC77_RS07195	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LOC77_RS07205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LOC77_RS07210	COG1136	(ABC) transporter
LOC77_RS07215	COG0577	efflux transmembrane transporter activity
LOC77_RS07220	COG1349	DNA-binding transcription factor activity
LOC77_RS07225	COG1105	Belongs to the carbohydrate kinase PfkB family
LOC77_RS07230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOC77_RS07230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOC77_RS07230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOC77_RS07235	COG0681	Belongs to the peptidase S26 family
LOC77_RS07245	COG0488	(ABC) transporter
LOC77_RS07250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LOC77_RS07255	COG2309	aminopeptidase activity
LOC77_RS07265	COG1077	Cell shape determining protein MreB Mrl
LOC77_RS07270	COG2002	toxin-antitoxin pair type II binding
LOC77_RS07275	COG3852	Histidine kinase
LOC77_RS07280	COG2105	PFAM AIG2 family protein
LOC77_RS07280	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LOC77_RS07285	COG0569	domain protein
LOC77_RS07295	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LOC77_RS07305	COG0561	phosphatase activity
LOC77_RS07310	COG0242	peptide deformylase activity
LOC77_RS07320	COG0497	DNA recombination
LOC77_RS07330	COG3321	synthase
LOC77_RS07330	COG4221	oxidoreductase activity
LOC77_RS07330	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS07330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS07335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOC77_RS07335	COG0300	oxidoreductase activity
LOC77_RS07335	COG3321	synthase
LOC77_RS07335	COG4221	oxidoreductase activity
LOC77_RS07340	COG3321	synthase
LOC77_RS07340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS07340	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS07340	COG4221	oxidoreductase activity
LOC77_RS07345	COG3321	synthase
LOC77_RS07345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOC77_RS07345	COG4221	oxidoreductase activity
LOC77_RS07345	COG0300	oxidoreductase activity
LOC77_RS07350	COG0300	oxidoreductase activity
LOC77_RS07350	COG3321	synthase
LOC77_RS07350	COG4221	oxidoreductase activity
LOC77_RS07350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOC77_RS07355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOC77_RS07355	COG0300	oxidoreductase activity
LOC77_RS07355	COG3321	synthase
LOC77_RS07355	COG4221	oxidoreductase activity
LOC77_RS07360	COG3321	synthase
LOC77_RS07360	COG4221	oxidoreductase activity
LOC77_RS07360	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS07360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS07365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LOC77_RS07370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LOC77_RS07375	COG0022	dehydrogenase e1 component
LOC77_RS07380	COG0508	dehydrogenase complex catalyzes the overall conversion of
LOC77_RS07385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LOC77_RS07390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LOC77_RS07405	COG1982	Orn Lys Arg decarboxylase major
LOC77_RS07425	COG0483	inositol monophosphate 1-phosphatase activity
LOC77_RS07435	COG3227	Zinc metalloprotease (Elastase)
LOC77_RS07450	COG1595	DNA-templated transcription, initiation
LOC77_RS07470	COG1217	gtp-binding protein TYPA
LOC77_RS07480	COG4896	Protein conserved in bacteria
LOC77_RS07490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LOC77_RS07495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LOC77_RS07500	COG2066	Belongs to the glutaminase family
LOC77_RS07510	COG0772	Belongs to the SEDS family
LOC77_RS07515	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LOC77_RS07530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LOC77_RS07530	COG2010	Cytochrome c
LOC77_RS07535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LOC77_RS07540	COG1845	cytochrome c oxidase, subunit III
LOC77_RS07545	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LOC77_RS07550	COG3336	cytochrome c oxidase
LOC77_RS07560	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LOC77_RS07565	COG2340	Cysteine-rich secretory protein family
LOC77_RS07580	COG3679	Belongs to the UPF0342 family
LOC77_RS07595	COG0742	ribosomal rna small subunit methyltransferase
LOC77_RS07605	COG3314	Sporulation integral membrane protein YlbJ
LOC77_RS07610	COG1752	Esterase of the alpha-beta hydrolase superfamily
LOC77_RS07615	COG3480	Lon protease (S16) C-terminal proteolytic domain
LOC77_RS07625	COG1399	metal-binding, possibly nucleic acid-binding protein
LOC77_RS07645	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LOC77_RS07665	COG4839	cell division protein FtsL
LOC77_RS07670	COG0768	penicillin binding
LOC77_RS07675	COG0768	penicillin binding
LOC77_RS07695	COG0772	Belongs to the SEDS family
LOC77_RS07710	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LOC77_RS07715	COG0849	cell division
LOC77_RS07720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LOC77_RS07725	COG1404	Belongs to the peptidase S8 family
LOC77_RS07725	COG4412	M6 family metalloprotease domain protein
LOC77_RS07735	COG1191	sigma factor activity
LOC77_RS07740	COG1191	sigma factor activity
LOC77_RS07745	COG1119	ATPase activity
LOC77_RS07750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LOC77_RS07755	COG1873	PFAM PRC-barrel domain
LOC77_RS07760	COG1496	oxidoreductase activity
LOC77_RS07765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LOC77_RS07775	COG0762	integral membrane protein
LOC77_RS07780	COG2302	S4 RNA-binding domain
LOC77_RS07785	COG3599	regulation of cell shape
LOC77_RS07790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LOC77_RS07795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LOC77_RS07805	COG0564	pseudouridine synthase activity
LOC77_RS07815	COG2233	PERMEase
LOC77_RS07825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LOC77_RS07830	COG0505	Belongs to the CarA family
LOC77_RS07835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LOC77_RS07850	COG0284	orotidine-5'-phosphate decarboxylase activity
LOC77_RS07855	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LOC77_RS07865	COG0306	phosphate transporter
LOC77_RS07880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LOC77_RS07885	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
LOC77_RS07890	COG1648	precorrin-2 dehydrogenase activity
LOC77_RS07900	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LOC77_RS07905	COG1561	YicC-like family, N-terminal region
LOC77_RS07915	COG0194	GDP metabolic process
LOC77_RS07925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LOC77_RS07930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LOC77_RS07935	COG0242	peptide deformylase activity
LOC77_RS07945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LOC77_RS07945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LOC77_RS07955	COG0631	protein serine/threonine phosphatase activity
LOC77_RS07960	COG0515	serine threonine protein kinase
LOC77_RS07960	COG2815	serine threonine protein kinase
LOC77_RS07970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LOC77_RS07975	COG1564	THIamine pyrophosphokinase
LOC77_RS07990	COG1302	Protein conserved in bacteria
LOC77_RS07995	COG1461	Dihydroxyacetone kinase
LOC77_RS08000	COG1760	l-serine dehydratase
LOC77_RS08005	COG1760	l-serine dehydratase
LOC77_RS08010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LOC77_RS08025	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LOC77_RS08030	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS08045	COG1196	nuclear chromosome segregation
LOC77_RS08050	COG0552	protein localization to endoplasmic reticulum
LOC77_RS08065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LOC77_RS08075	COG1837	Belongs to the UPF0109 family
LOC77_RS08100	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LOC77_RS08115	COG2257	FlhB HrpN YscU SpaS Family
LOC77_RS08125	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LOC77_RS08130	COG0758	DNA mediated transformation
LOC77_RS08135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LOC77_RS08145	COG4974	Belongs to the 'phage' integrase family
LOC77_RS08165	COG1815	bacterial-type flagellum-dependent cell motility
LOC77_RS08170	COG1558	bacterial-type flagellum-dependent cell motility
LOC77_RS08175	COG1677	Flagellar hook-basal body complex protein FliE
LOC77_RS08180	COG1766	The M ring may be actively involved in energy transduction
LOC77_RS08185	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LOC77_RS08190	COG1317	bacterial-type flagellum organization
LOC77_RS08195	COG1157	protein secretion by the type III secretion system
LOC77_RS08200	COG2882	bacterial-type flagellum organization
LOC77_RS08205	COG3334	PFAM MgtE intracellular
LOC77_RS08210	COG3144	bacterial-type flagellum assembly
LOC77_RS08215	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LOC77_RS08220	COG4786	Flagellar basal body rod
LOC77_RS08225	COG1582	Flagellar protein (FlbD)
LOC77_RS08230	COG1580	Controls the rotational direction of flagella during chemotaxis
LOC77_RS08235	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LOC77_RS08240	COG1776	CheC inhibitor of MCP methylation
LOC77_RS08240	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LOC77_RS08245	COG2201	protein-glutamate methylesterase activity
LOC77_RS08250	COG3190	flagellar
LOC77_RS08255	COG1338	Plays a role in the flagellum-specific transport system
LOC77_RS08260	COG1987	bacterial-type flagellum assembly
LOC77_RS08265	COG1684	flagellar biosynthetic protein fliR
LOC77_RS08270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LOC77_RS08275	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LOC77_RS08280	COG1419	protein localization to endoplasmic reticulum
LOC77_RS08285	COG0455	bacterial-type flagellum organization
LOC77_RS08290	COG2201	protein-glutamate methylesterase activity
LOC77_RS08295	COG0643	Histidine kinase
LOC77_RS08295	COG2198	Histidine kinase
LOC77_RS08300	COG0835	chemotaxis
LOC77_RS08305	COG1776	CheC inhibitor of MCP methylation
LOC77_RS08315	COG1191	sigma factor activity
LOC77_RS08345	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LOC77_RS08350	COG4589	Belongs to the CDS family
LOC77_RS08360	COG0750	zinc metalloprotease
LOC77_RS08380	COG0195	Participates in both transcription termination and antitermination
LOC77_RS08385	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LOC77_RS08390	COG1358	cellular component organization or biogenesis
LOC77_RS08400	COG1550	Protein conserved in bacteria
LOC77_RS08415	COG0196	riboflavin kinase activity
LOC77_RS08430	COG0726	polysaccharide deacetylase
LOC77_RS08435	COG0612	Peptidase, M16
LOC77_RS08440	COG1873	PFAM PRC-barrel domain
LOC77_RS08445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOC77_RS08450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LOC77_RS08455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LOC77_RS08460	COG0527	aspartate kinase activity
LOC77_RS08470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LOC77_RS08475	COG0740	serine-type endopeptidase activity
LOC77_RS08485	COG1674	ftsk spoiiie
LOC77_RS08485	COG4980	gas vesicle protein
LOC77_RS08490	COG2188	Transcriptional regulator
LOC77_RS08495	COG2814	Major facilitator Superfamily
LOC77_RS08500	COG1846	Transcriptional regulator
LOC77_RS08505	COG1033	growth of symbiont in host cell
LOC77_RS08505	COG2409	Drug exporters of the RND superfamily
LOC77_RS08510	COG0612	Peptidase, M16
LOC77_RS08515	COG0612	Peptidase, M16
LOC77_RS08520	COG0300	oxidoreductase activity
LOC77_RS08535	COG1426	Protein conserved in bacteria
LOC77_RS08540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LOC77_RS08555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LOC77_RS08565	COG1692	metallophosphoesterase
LOC77_RS08570	COG2359	stage V sporulation protein S
LOC77_RS08590	COG4550	Control of competence regulator ComK, YlbF/YmcA
LOC77_RS08635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOC77_RS08640	COG3425	synthase
LOC77_RS08645	COG1024	Enoyl-CoA hydratase
LOC77_RS08650	COG1024	Enoyl-CoA hydratase
LOC77_RS08655	COG0300	oxidoreductase activity
LOC77_RS08655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS08655	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS08655	COG0318	PFAM AMP-dependent synthetase and ligase
LOC77_RS08655	COG3321	synthase
LOC77_RS08660	COG3321	synthase
LOC77_RS08660	COG0300	oxidoreductase activity
LOC77_RS08660	COG4221	oxidoreductase activity
LOC77_RS08660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOC77_RS08665	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS08665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS08665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOC77_RS08665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOC77_RS08665	COG3321	synthase
LOC77_RS08665	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS08665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS08665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LOC77_RS08665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LOC77_RS08665	COG3321	synthase
LOC77_RS08670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS08670	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS08670	COG3321	synthase
LOC77_RS08670	COG4221	oxidoreductase activity
LOC77_RS08675	COG3321	synthase
LOC77_RS08675	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LOC77_RS08675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOC77_RS08675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LOC77_RS08680	COG2124	cytochrome p450
LOC77_RS08685	COG3209	COG3209 Rhs family protein
LOC77_RS08690	COG3619	membrane
LOC77_RS08700	COG1404	Belongs to the peptidase S8 family
LOC77_RS08710	COG4195	phage-related replication protein
LOC77_RS08715	COG1764	response to oxidative stress
LOC77_RS08725	COG2076	Multidrug Resistance protein
LOC77_RS08765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOC77_RS08770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOC77_RS08775	COG4112	unkown
LOC77_RS08780	COG0860	N-Acetylmuramoyl-L-alanine amidase
LOC77_RS08785	COG0464	growth
LOC77_RS08790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LOC77_RS08795	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LOC77_RS08800	COG0789	Transcriptional regulator
LOC77_RS08805	COG0174	glutamine synthetase
LOC77_RS08815	COG2211	Major facilitator Superfamily
LOC77_RS08820	COG3507	Belongs to the glycosyl hydrolase 43 family
LOC77_RS08835	COG1070	Carbohydrate kinase
LOC77_RS08840	COG3848	Pyruvate phosphate dikinase
LOC77_RS08840	COG0574	Belongs to the PEP-utilizing enzyme family
LOC77_RS08860	COG2378	regulation of single-species biofilm formation
LOC77_RS08865	COG2318	DinB family
LOC77_RS08870	COG1064	alcohol dehydrogenase
LOC77_RS08890	COG0456	acetyltransferase
LOC77_RS08910	COG3397	chitin binding
LOC77_RS08930	COG5434	Belongs to the glycosyl hydrolase 28 family
LOC77_RS08935	COG0756	dUTP diphosphatase activity
LOC77_RS08940	COG4195	phage-related replication protein
LOC77_RS08975	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LOC77_RS08985	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LOC77_RS09005	COG0785	Cytochrome C biogenesis protein
LOC77_RS09010	COG2201	protein-glutamate methylesterase activity
LOC77_RS09015	COG4846	Membrane protein involved in cytochrome C biogenesis
LOC77_RS09025	COG0071	Belongs to the small heat shock protein (HSP20) family
LOC77_RS09040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LOC77_RS09045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LOC77_RS09065	COG0824	Thioesterase
LOC77_RS09075	COG4841	protein insertion into membrane
LOC77_RS09085	COG1832	CoA-binding protein
LOC77_RS09090	COG0187	DNA topoisomerase II activity
LOC77_RS09095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LOC77_RS09105	COG1115	amino acid carrier protein
LOC77_RS09115	COG1063	alcohol dehydrogenase
LOC77_RS09120	COG0800	Aldolase
LOC77_RS09125	COG1312	Catalyzes the dehydration of D-mannonate
LOC77_RS09130	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS09135	COG1609	Transcriptional regulator
LOC77_RS09140	COG2271	Major facilitator Superfamily
LOC77_RS09185	COG2205	protein histidine kinase activity
LOC77_RS09190	COG0745	RESPONSE REGULATOR receiver
LOC77_RS09200	COG3507	Belongs to the glycosyl hydrolase 43 family
LOC77_RS09225	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS09230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LOC77_RS09235	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LOC77_RS09240	COG2610	gluconate transmembrane transporter activity
LOC77_RS09245	COG2124	cytochrome p450
LOC77_RS09265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LOC77_RS09275	COG2246	polysaccharide biosynthetic process
LOC77_RS09280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LOC77_RS09285	COG0586	Pfam SNARE associated Golgi protein
LOC77_RS09290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LOC77_RS09295	COG1024	Enoyl-CoA hydratase
LOC77_RS09300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LOC77_RS09305	COG0511	ligase activity, forming carbon-carbon bonds
LOC77_RS09310	COG0439	Biotin carboxylase
LOC77_RS09315	COG0318	PFAM AMP-dependent synthetase and ligase
LOC77_RS09320	COG1960	acyl-CoA dehydrogenase activity
LOC77_RS09325	COG1649	PFAM Uncharacterised BCR, COG1649
LOC77_RS09335	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LOC77_RS09335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS09340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS09345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS09350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS09355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS09360	COG2027	D-alanyl-D-alanine carboxypeptidase
LOC77_RS09365	COG2017	converts alpha-aldose to the beta-anomer
LOC77_RS09370	COG0534	Mate efflux family protein
LOC77_RS09380	COG5444	nuclease activity
LOC77_RS09425	COG5434	Belongs to the glycosyl hydrolase 28 family
LOC77_RS09430	COG1705	Flagellar rod assembly protein muramidase FlgJ
LOC77_RS09440	COG3953	SLT domain
LOC77_RS09440	COG5280	Phage tail tape measure protein TP901
LOC77_RS09525	COG0582	viral genome integration into host DNA
LOC77_RS09530	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LOC77_RS09655	COG0582	viral genome integration into host DNA
LOC77_RS09660	COG0166	Belongs to the GPI family
LOC77_RS09665	COG0405	Gamma-glutamyltransferase
LOC77_RS09670	COG2814	Major facilitator Superfamily
LOC77_RS09675	COG0640	Transcriptional regulator
LOC77_RS09685	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LOC77_RS09695	COG0604	alcohol dehydrogenase
LOC77_RS09700	COG0493	'glutamate synthase
LOC77_RS09705	COG0067	glutamate synthase
LOC77_RS09705	COG0070	glutamate synthase
LOC77_RS09705	COG0069	glutamate synthase activity
LOC77_RS09710	COG0583	DNA-binding transcription factor activity
LOC77_RS09715	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LOC77_RS09730	COG0300	oxidoreductase activity
LOC77_RS09735	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LOC77_RS09745	COG2814	Major facilitator Superfamily
LOC77_RS09750	COG1070	Carbohydrate kinase
LOC77_RS09755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LOC77_RS09760	COG0243	molybdopterin cofactor binding
LOC77_RS09780	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS09785	COG1733	regulation of RNA biosynthetic process
LOC77_RS09790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LOC77_RS09795	COG0662	Cupin 2, conserved barrel domain protein
LOC77_RS09795	COG2207	Transcriptional regulator
LOC77_RS09800	COG1309	transcriptional regulator
LOC77_RS09805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LOC77_RS09815	COG0640	Transcriptional regulator
LOC77_RS09820	COG0741	lytic transglycosylase activity
LOC77_RS09825	COG2322	membrane
LOC77_RS09840	COG1619	proteins homologs of microcin C7 resistance protein MccF
LOC77_RS09850	COG3584	3D domain protein
LOC77_RS09850	COG1388	LysM domain
LOC77_RS09855	COG0514	ATP-dependent DNA helicase (RecQ)
LOC77_RS09865	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LOC77_RS09870	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LOC77_RS09885	COG0071	Belongs to the small heat shock protein (HSP20) family
LOC77_RS09915	COG1012	belongs to the aldehyde dehydrogenase family
LOC77_RS09920	COG1657	PFAM Prenyltransferase squalene oxidase
LOC77_RS09925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LOC77_RS09930	COG0733	neurotransmitter:sodium symporter activity
LOC77_RS09935	COG0385	Bile acid
LOC77_RS09940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LOC77_RS09945	COG0508	dehydrogenase complex catalyzes the overall conversion of
LOC77_RS09955	COG4548	von Willebrand factor, type A
LOC77_RS09960	COG0714	Associated with various cellular activities
LOC77_RS09965	COG2032	superoxide dismutase activity
LOC77_RS09970	COG0791	NLP P60 protein
LOC77_RS09970	COG1388	LysM domain
LOC77_RS09975	COG1819	glycosyl
LOC77_RS09980	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LOC77_RS09985	COG0534	Mate efflux family protein
LOC77_RS09990	COG1366	Belongs to the anti-sigma-factor antagonist family
LOC77_RS09995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LOC77_RS10000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LOC77_RS10010	COG2962	Rard protein
LOC77_RS10025	COG1942	4-Oxalocrotonate Tautomerase
LOC77_RS10035	COG1733	regulation of RNA biosynthetic process
LOC77_RS10040	COG0778	Nitroreductase
LOC77_RS10045	COG0400	carboxylic ester hydrolase activity
LOC77_RS10050	COG0346	lactoylglutathione lyase activity
LOC77_RS10060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOC77_RS10070	COG2723	6-phospho-beta-galactosidase activity
LOC77_RS10075	COG2188	Transcriptional regulator
LOC77_RS10080	COG3409	Peptidoglycan-binding domain 1 protein
LOC77_RS10080	COG0793	Belongs to the peptidase S41A family
LOC77_RS10085	COG2226	methyltransferase
LOC77_RS10095	COG1876	peptidase activity
LOC77_RS10115	COG0671	phosphoesterase, PA-phosphatase related
LOC77_RS10150	COG1509	lysine 2,3-aminomutase activity
LOC77_RS10155	COG0456	acetyltransferase
LOC77_RS10160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LOC77_RS10165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LOC77_RS10170	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LOC77_RS10175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LOC77_RS10180	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LOC77_RS10190	COG0456	acetyltransferase
LOC77_RS10195	COG0463	Glycosyl transferase, family 2
LOC77_RS10210	COG4641	Protein conserved in bacteria
LOC77_RS10220	COG1086	Polysaccharide biosynthesis protein
LOC77_RS10275	COG0457	Tetratricopeptide repeat
LOC77_RS10285	COG3391	amine dehydrogenase activity
LOC77_RS10330	COG5444	nuclease activity
LOC77_RS10335	COG4282	regulation of fungal-type cell wall biogenesis
LOC77_RS10370	COG1846	Transcriptional regulator
LOC77_RS10375	COG4698	Protein conserved in bacteria
LOC77_RS10380	COG2755	lipolytic protein G-D-S-L family
LOC77_RS10385	COG1999	signal sequence binding
LOC77_RS10395	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LOC77_RS10400	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LOC77_RS10405	COG1272	protein, Hemolysin III
LOC77_RS10410	COG0204	Acyl-transferase
LOC77_RS10415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LOC77_RS10430	COG2136	Putative SAM-dependent methyltransferase
LOC77_RS10430	COG2521	methyltransferase
LOC77_RS10445	COG1413	lyase activity
LOC77_RS10450	COG1418	mRNA catabolic process
LOC77_RS10455	COG0386	Belongs to the glutathione peroxidase family
LOC77_RS10465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LOC77_RS10475	COG1278	Cold shock
LOC77_RS10495	COG0328	RNA-DNA hybrid ribonuclease activity
LOC77_RS10500	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LOC77_RS10505	COG0328	RNA-DNA hybrid ribonuclease activity
LOC77_RS10515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LOC77_RS10530	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LOC77_RS10540	COG1755	Isoprenylcysteine carboxyl methyltransferase
LOC77_RS10545	COG3424	synthase
LOC77_RS10570	COG1335	isochorismatase
LOC77_RS10585	COG3331	DNA recombination
LOC77_RS10655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LOC77_RS10660	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LOC77_RS10685	COG4112	unkown
LOC77_RS10690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LOC77_RS10695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOC77_RS10715	COG1780	Probably involved in ribonucleotide reductase function
LOC77_RS10805	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
LOC77_RS10810	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LOC77_RS10825	COG3584	3D domain protein
LOC77_RS10830	COG0587	DNA-directed DNA polymerase activity
LOC77_RS10835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LOC77_RS10840	COG0358	DNA primase activity
LOC77_RS10845	COG0305	Participates in initiation and elongation during chromosome replication
LOC77_RS10855	COG2887	Belongs to the helicase family. UvrD subfamily
LOC77_RS10890	COG3420	alginic acid biosynthetic process
LOC77_RS10890	COG5434	Belongs to the glycosyl hydrolase 28 family
LOC77_RS10895	COG4195	phage-related replication protein
LOC77_RS10920	COG2135	peptidase activity
LOC77_RS10925	COG1793	dna ligase
LOC77_RS10930	COG0756	dUTP diphosphatase activity
LOC77_RS10965	COG4474	Belongs to the UPF0398 family
LOC77_RS10995	COG3655	Transcriptional regulator
LOC77_RS11045	COG3655	Transcriptional regulator
LOC77_RS11170	COG3655	Transcriptional regulator
LOC77_RS11260	COG0776	regulation of translation
LOC77_RS11390	COG0582	viral genome integration into host DNA
LOC77_RS11410	COG0739	heme binding
LOC77_RS11410	COG0741	lytic transglycosylase activity
LOC77_RS11410	COG1196	nuclear chromosome segregation
LOC77_RS11420	COG2433	Pfam Transposase IS66
LOC77_RS11430	COG5434	Belongs to the glycosyl hydrolase 28 family
LOC77_RS11435	COG5632	N-Acetylmuramoyl-L-alanine amidase
LOC77_RS11435	COG3409	Peptidoglycan-binding domain 1 protein
LOC77_RS11455	COG0457	Tetratricopeptide repeat
LOC77_RS11460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOC77_RS11490	COG5444	nuclease activity
LOC77_RS11500	COG4282	regulation of fungal-type cell wall biogenesis
LOC77_RS11505	COG1525	nuclease
LOC77_RS11525	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LOC77_RS11530	COG1199	ATP-dependent helicase activity
LOC77_RS11545	COG0116	Belongs to the methyltransferase superfamily
LOC77_RS11575	COG3359	exonuclease
LOC77_RS11580	COG1111	helicase
LOC77_RS11580	COG1205	dead DEAH box helicase
LOC77_RS11585	COG2190	(PTS) system
LOC77_RS11590	COG0071	Belongs to the small heat shock protein (HSP20) family
LOC77_RS11630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LOC77_RS11630	COG4499	WXG100 protein secretion system (Wss), protein YukC
LOC77_RS11640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LOC77_RS11645	COG3935	DnaD domain protein
LOC77_RS11655	COG0436	Aminotransferase
LOC77_RS11660	COG5353	protein conserved in bacteria
LOC77_RS11670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LOC77_RS11670	COG1199	ATP-dependent helicase activity
LOC77_RS11700	COG0438	transferase activity, transferring glycosyl groups
LOC77_RS11705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LOC77_RS11720	COG1694	Mazg nucleotide pyrophosphohydrolase
LOC77_RS11725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOC77_RS11730	COG2140	Oxalate decarboxylase
LOC77_RS11740	COG4347	Protein of unknown function (DUF1405)
LOC77_RS11745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LOC77_RS11745	COG2010	Cytochrome c
LOC77_RS11750	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LOC77_RS11755	COG0723	plastoquinol--plastocyanin reductase activity
LOC77_RS11770	COG0457	Tetratricopeptide repeat
LOC77_RS11780	COG0287	Prephenate dehydrogenase
LOC77_RS11815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LOC77_RS11820	COG4401	Chorismate mutase type I
LOC77_RS11835	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LOC77_RS11840	COG0105	UTP biosynthetic process
LOC77_RS11845	COG0142	geranyltranstransferase activity
LOC77_RS11855	COG0142	geranyltranstransferase activity
LOC77_RS11870	COG0776	regulation of translation
LOC77_RS11875	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LOC77_RS11915	COG0539	negative regulation of cytoplasmic translation
LOC77_RS11930	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LOC77_RS11935	COG2959	enzyme of heme biosynthesis
LOC77_RS11940	COG3773	Cell wall hydrolase
LOC77_RS11940	COG3409	Peptidoglycan-binding domain 1 protein
LOC77_RS11945	COG2339	peptidase activity
LOC77_RS11950	COG0492	ferredoxin-NADP+ reductase activity
LOC77_RS11955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LOC77_RS11960	COG4862	establishment of competence for transformation
LOC77_RS11965	COG1408	metallophosphoesterase
LOC77_RS11975	COG1388	LysM domain
LOC77_RS11980	COG1266	CAAX protease self-immunity
LOC77_RS11985	COG0514	ATP-dependent DNA helicase (RecQ)
LOC77_RS11990	COG4955	Helix-turn-helix domain
LOC77_RS11995	COG1141	Ferredoxin
LOC77_RS12000	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LOC77_RS12005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LOC77_RS12015	COG1595	DNA-templated transcription, initiation
LOC77_RS12020	COG5002	protein histidine kinase activity
LOC77_RS12025	COG0745	RESPONSE REGULATOR receiver
LOC77_RS12030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LOC77_RS12035	COG1333	cytochrome c biogenesis protein
LOC77_RS12040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LOC77_RS12045	COG1187	pseudouridine synthase activity
LOC77_RS12050	COG0700	Nucleoside recognition
LOC77_RS12055	COG2715	membrane protein required for spore maturation
LOC77_RS12060	COG1686	Belongs to the peptidase S11 family
LOC77_RS12085	COG1547	Domain of unknown function (DUF309)
LOC77_RS12090	COG0456	acetyltransferase
LOC77_RS12105	COG0307	riboflavin synthase, alpha
LOC77_RS12110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LOC77_RS12110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LOC77_RS12120	COG0681	Belongs to the peptidase S26 family
LOC77_RS12130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LOC77_RS12135	COG4086	secreted protein
LOC77_RS12140	COG0019	diaminopimelate decarboxylase activity
LOC77_RS12145	COG0697	spore germination
LOC77_RS12160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LOC77_RS12180	COG1191	sigma factor activity
LOC77_RS12190	COG1366	Belongs to the anti-sigma-factor antagonist family
LOC77_RS12195	COG1686	Belongs to the peptidase S11 family
LOC77_RS12200	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LOC77_RS12205	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LOC77_RS12210	COG4974	Belongs to the 'phage' integrase family
LOC77_RS12220	COG0735	belongs to the Fur family
LOC77_RS12225	COG1300	Membrane
LOC77_RS12240	COG0281	malic enzyme
LOC77_RS12245	COG1757	Na H antiporter
LOC77_RS12250	COG1027	Aspartate ammonia-lyase
LOC77_RS12255	COG0252	asparaginase activity
LOC77_RS12260	COG1396	sequence-specific DNA binding
LOC77_RS12265	COG1379	DNA repair
LOC77_RS12270	COG0494	nUDIX hydrolase
LOC77_RS12280	COG0667	Aldo Keto reductase
LOC77_RS12290	COG1073	alpha beta
LOC77_RS12300	COG4918	Iron-sulphur cluster biosynthesis
LOC77_RS12305	COG0456	acetyltransferase
LOC77_RS12305	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LOC77_RS12310	COG2329	Antibiotic biosynthesis monooxygenase
LOC77_RS12315	COG0456	acetyltransferase
LOC77_RS12320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOC77_RS12335	COG0628	permease
LOC77_RS12345	COG0346	lactoylglutathione lyase activity
LOC77_RS12355	COG3048	D-serine ammonia-lyase activity
LOC77_RS12360	COG0300	oxidoreductase activity
LOC77_RS12365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LOC77_RS12370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LOC77_RS12375	COG1024	Enoyl-CoA hydratase
LOC77_RS12380	COG3425	synthase
LOC77_RS12385	COG2124	cytochrome p450
LOC77_RS12390	COG3321	synthase
LOC77_RS12390	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS12390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS12390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOC77_RS12390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LOC77_RS12395	COG3321	synthase
LOC77_RS12395	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS12395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS12395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LOC77_RS12395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOC77_RS12400	COG0318	PFAM AMP-dependent synthetase and ligase
LOC77_RS12400	COG0300	oxidoreductase activity
LOC77_RS12400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS12400	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS12400	COG3321	synthase
LOC77_RS12405	COG3321	synthase
LOC77_RS12405	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS12405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS12405	COG0318	PFAM AMP-dependent synthetase and ligase
LOC77_RS12405	COG0300	oxidoreductase activity
LOC77_RS12410	COG3321	synthase
LOC77_RS12410	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS12410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LOC77_RS12410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOC77_RS12410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS12415	COG3321	synthase
LOC77_RS12415	COG0300	oxidoreductase activity
LOC77_RS12415	COG0318	PFAM AMP-dependent synthetase and ligase
LOC77_RS12415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS12415	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS12420	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS12420	COG3321	synthase
LOC77_RS12420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LOC77_RS12420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS12420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOC77_RS12425	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS12430	COG0318	PFAM AMP-dependent synthetase and ligase
LOC77_RS12445	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LOC77_RS12445	COG2070	2-Nitropropane dioxygenase
LOC77_RS12450	COG0250	Participates in transcription elongation, termination and antitermination
LOC77_RS12470	COG0596	Alpha beta hydrolase
LOC77_RS12485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LOC77_RS12490	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LOC77_RS12505	COG0706	membrane insertase activity
LOC77_RS12510	COG2195	Cleaves the N-terminal amino acid of tripeptides
LOC77_RS12515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LOC77_RS12520	COG0346	lactoylglutathione lyase activity
LOC77_RS12530	COG1376	ErfK ybiS ycfS ynhG family protein
LOC77_RS12535	COG4129	membrane
LOC77_RS12540	COG1126	abc transporter atp-binding protein
LOC77_RS12545	COG0765	amino acid transport
LOC77_RS12550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LOC77_RS12560	COG1597	lipid kinase activity
LOC77_RS12565	COG0508	dehydrogenase complex catalyzes the overall conversion of
LOC77_RS12570	COG0022	dehydrogenase e1 component
LOC77_RS12575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LOC77_RS12580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LOC77_RS12585	COG3426	butyrate kinase activity
LOC77_RS12590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LOC77_RS12595	COG0280	phosphate acetyltransferase
LOC77_RS12600	COG3290	protein histidine kinase activity
LOC77_RS12600	COG3829	transcription factor binding
LOC77_RS12610	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LOC77_RS12615	COG2079	MmgE PrpD family protein
LOC77_RS12620	COG0372	Belongs to the citrate synthase family
LOC77_RS12625	COG1960	acyl-CoA dehydrogenase activity
LOC77_RS12630	COG1250	3-hydroxyacyl-CoA dehydrogenase
LOC77_RS12635	COG0183	Belongs to the thiolase family
LOC77_RS12640	COG0584	glycerophosphoryl diester phosphodiesterase
LOC77_RS12645	COG0860	N-Acetylmuramoyl-L-alanine amidase
LOC77_RS12670	COG1902	pentaerythritol trinitrate reductase activity
LOC77_RS12685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LOC77_RS12690	COG0745	RESPONSE REGULATOR receiver
LOC77_RS12695	COG0750	zinc metalloprotease
LOC77_RS12700	COG0497	DNA recombination
LOC77_RS12710	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LOC77_RS12720	COG0142	geranyltranstransferase activity
LOC77_RS12730	COG1570	exodeoxyribonuclease VII activity
LOC77_RS12745	COG1302	Protein conserved in bacteria
LOC77_RS12750	COG0439	Biotin carboxylase
LOC77_RS12755	COG0511	ligase activity, forming carbon-carbon bonds
LOC77_RS12795	COG3854	ATPases associated with a variety of cellular activities
LOC77_RS12810	COG0006	proline dipeptidase activity
LOC77_RS12820	COG3872	metal-dependent enzyme
LOC77_RS12830	COG1752	Esterase of the alpha-beta hydrolase superfamily
LOC77_RS12845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LOC77_RS12865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LOC77_RS12880	COG1396	sequence-specific DNA binding
LOC77_RS12890	COG0681	Belongs to the peptidase S26 family
LOC77_RS12915	COG4940	Competence protein ComGF
LOC77_RS12925	COG4970	Tfp pilus assembly protein FimT
LOC77_RS12930	COG4537	Required for transformation and DNA binding
LOC77_RS12935	COG1459	type II secretion system
LOC77_RS12940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LOC77_RS12945	COG0598	Magnesium transport protein CorA
LOC77_RS12950	COG1253	flavin adenine dinucleotide binding
LOC77_RS12955	COG1366	Belongs to the anti-sigma-factor antagonist family
LOC77_RS12965	COG1393	Belongs to the ArsC family
LOC77_RS12975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LOC77_RS12985	COG0011	TIGRFAM Protein of
LOC77_RS12995	COG2866	Carboxypeptidase
LOC77_RS13000	COG1940	carbohydrate kinase activity
LOC77_RS13005	COG4483	Protein conserved in bacteria
LOC77_RS13010	COG1757	Na H antiporter
LOC77_RS13020	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LOC77_RS13035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LOC77_RS13040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LOC77_RS13045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LOC77_RS13050	COG0581	inorganic phosphate transmembrane transporter activity
LOC77_RS13055	COG0573	inorganic phosphate transmembrane transporter activity
LOC77_RS13060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LOC77_RS13065	COG0768	penicillin binding
LOC77_RS13070	COG0477	Major facilitator Superfamily
LOC77_RS13075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LOC77_RS13080	COG2839	Protein conserved in bacteria
LOC77_RS13085	COG5521	maltodextrose utilization protein MalA
LOC77_RS13090	COG1388	LysM domain
LOC77_RS13100	COG4709	membrane
LOC77_RS13105	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
LOC77_RS13110	COG0735	belongs to the Fur family
LOC77_RS13115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOC77_RS13135	COG0513	Belongs to the DEAD box helicase family
LOC77_RS13150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LOC77_RS13155	COG2384	SAM-dependent methyltransferase
LOC77_RS13160	COG2010	Cytochrome c
LOC77_RS13165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOC77_RS13170	COG0358	DNA primase activity
LOC77_RS13185	COG0517	IMP dehydrogenase activity
LOC77_RS13190	COG0751	glycine-tRNA ligase activity
LOC77_RS13210	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LOC77_RS13215	COG0295	cytidine deaminase activity
LOC77_RS13220	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LOC77_RS13230	COG1480	7TM receptor with intracellular HD hydrolase
LOC77_RS13235	COG1702	phosphate starvation-inducible protein PhoH
LOC77_RS13240	COG0561	phosphatase activity
LOC77_RS13255	COG4864	UPF0365 protein
LOC77_RS13260	COG1030	water channel activity
LOC77_RS13265	COG1610	YqeY-like protein
LOC77_RS13275	COG1283	sodium-dependent phosphate transmembrane transporter activity
LOC77_RS13280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LOC77_RS13285	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LOC77_RS13315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LOC77_RS13330	COG0860	N-Acetylmuramoyl-L-alanine amidase
LOC77_RS13360	COG0658	competence protein
LOC77_RS13360	COG2333	competence protein COMEC
LOC77_RS13365	COG2131	deaminase
LOC77_RS13370	COG1555	photosystem II stabilization
LOC77_RS13370	COG1596	polysaccharide export
LOC77_RS13375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LOC77_RS13380	COG2226	methyltransferase
LOC77_RS13385	COG0799	negative regulation of ribosome biogenesis
LOC77_RS13390	COG1713	HD superfamily hydrolase involved in NAD metabolism
LOC77_RS13400	COG1534	Rna-binding protein
LOC77_RS13405	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LOC77_RS13410	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LOC77_RS13415	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LOC77_RS13425	COG2755	lipolytic protein G-D-S-L family
LOC77_RS13435	COG0398	Pfam SNARE associated Golgi protein
LOC77_RS13460	COG2207	Transcriptional regulator
LOC77_RS13460	COG3708	Transcriptional regulator
LOC77_RS13465	COG0563	adenylate kinase activity
LOC77_RS13470	COG2814	Major facilitator Superfamily
LOC77_RS13475	COG0456	acetyltransferase
LOC77_RS13480	COG2318	DinB family
LOC77_RS13490	COG0561	phosphatase activity
LOC77_RS13495	COG0561	phosphatase activity
LOC77_RS13505	COG1482	cell wall glycoprotein biosynthetic process
LOC77_RS13510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOC77_RS13510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOC77_RS13510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LOC77_RS13515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOC77_RS13515	COG3711	transcriptional antiterminator
LOC77_RS13525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LOC77_RS13530	COG0583	DNA-binding transcription factor activity
LOC77_RS13535	COG2814	Major facilitator Superfamily
LOC77_RS13540	COG2124	cytochrome p450
LOC77_RS13540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LOC77_RS13545	COG1309	transcriptional regulator
LOC77_RS13550	COG2226	methyltransferase
LOC77_RS13565	COG2116	formate transmembrane transporter activity
LOC77_RS13570	COG5609	conserved protein (DUF2294)
LOC77_RS13575	COG3383	formate dehydrogenase (NAD+) activity
LOC77_RS13580	COG2427	Protein of unknown function (DUF1641)
LOC77_RS13590	COG0626	cystathionine gamma-synthase activity
LOC77_RS13595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LOC77_RS13620	COG0768	penicillin binding
LOC77_RS13635	COG0826	peptidase U32
LOC77_RS13640	COG0826	peptidase U32
LOC77_RS13645	COG4122	O-methyltransferase activity
LOC77_RS13650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LOC77_RS13665	COG4472	Bacterial protein of unknown function (DUF965)
LOC77_RS13675	COG0628	permease
LOC77_RS13680	COG1126	abc transporter atp-binding protein
LOC77_RS13685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LOC77_RS13690	COG0765	amino acid transport
LOC77_RS13695	COG0765	amino acid transport
LOC77_RS13710	COG3881	PFAM PRC-barrel domain
LOC77_RS13715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LOC77_RS13720	COG0457	Tetratricopeptide repeat
LOC77_RS13730	COG1104	cysteine desulfurase activity
LOC77_RS13735	COG1959	2 iron, 2 sulfur cluster binding
LOC77_RS13740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LOC77_RS13745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LOC77_RS13770	COG4991	sh3 domain protein
LOC77_RS13770	COG0860	N-Acetylmuramoyl-L-alanine amidase
LOC77_RS13770	COG3103	Sh3 type 3 domain protein
LOC77_RS13780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LOC77_RS13790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LOC77_RS13790	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LOC77_RS13795	COG5416	Lipopolysaccharide assembly protein A domain
LOC77_RS13800	COG0490	domain, Protein
LOC77_RS13805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LOC77_RS13805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LOC77_RS13815	COG2244	polysaccharide biosynthetic process
LOC77_RS13820	COG2323	membrane
LOC77_RS13830	COG1862	Preprotein translocase
LOC77_RS13870	COG1388	LysM domain
LOC77_RS13880	COG0157	Belongs to the NadC ModD family
LOC77_RS13885	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LOC77_RS13890	COG1104	cysteine desulfurase activity
LOC77_RS13895	COG1827	regulation of RNA biosynthetic process
LOC77_RS13900	COG0077	Prephenate dehydratase
LOC77_RS13915	COG3290	protein histidine kinase activity
LOC77_RS13920	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LOC77_RS13925	COG2868	ribosomal protein
LOC77_RS13935	COG1994	Peptidase M50
LOC77_RS13940	COG0739	heme binding
LOC77_RS13945	COG2894	cell division
LOC77_RS13955	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LOC77_RS13965	COG1077	Cell shape determining protein MreB Mrl
LOC77_RS13985	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LOC77_RS13990	COG0285	dihydrofolate synthase activity
LOC77_RS13995	COG0525	valine-tRNA ligase activity
LOC77_RS14005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LOC77_RS14010	COG1388	LysM domain
LOC77_RS14020	COG0113	porphobilinogen synthase activity
LOC77_RS14025	COG1587	Uroporphyrinogen-III synthase
LOC77_RS14035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LOC77_RS14055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LOC77_RS14060	COG0470	DNA polymerase III
LOC77_RS14060	COG1067	ATP-dependent peptidase activity
LOC77_RS14075	COG0457	Tetratricopeptide repeat
LOC77_RS14075	COG1477	protein flavinylation
LOC77_RS14090	COG0473	3-isopropylmalate dehydrogenase activity
LOC77_RS14105	COG0440	acetolactate synthase activity
LOC77_RS14110	COG0028	Belongs to the TPP enzyme family
LOC77_RS14140	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LOC77_RS14160	COG0622	Phosphoesterase
LOC77_RS14165	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LOC77_RS14175	COG5401	PFAM Sporulation and spore germination
LOC77_RS14185	COG1846	Transcriptional regulator
LOC77_RS14190	COG2197	response regulator
LOC77_RS14195	COG0824	Thioesterase
LOC77_RS14200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LOC77_RS14205	COG1053	succinate dehydrogenase
LOC77_RS14210	COG2009	succinate dehydrogenase
LOC77_RS14215	COG1719	4-vinyl reductase, 4VR
LOC77_RS14220	COG0527	aspartate kinase activity
LOC77_RS14230	COG3118	belongs to the thioredoxin family
LOC77_RS14235	COG3534	alpha-L-arabinofuranosidase
LOC77_RS14240	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LOC77_RS14245	COG2086	electron transfer activity
LOC77_RS14250	COG1024	Enoyl-CoA hydratase
LOC77_RS14255	COG1309	transcriptional regulator
LOC77_RS14260	COG0318	PFAM AMP-dependent synthetase and ligase
LOC77_RS14270	COG3766	membrane
LOC77_RS14280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LOC77_RS14280	COG1796	DNA polymerase
LOC77_RS14285	COG1286	toxin biosynthetic process
LOC77_RS14300	COG0072	phenylalanine-tRNA ligase activity
LOC77_RS14300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LOC77_RS14305	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LOC77_RS14310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LOC77_RS14320	COG3835	regulator
LOC77_RS14325	COG0277	FAD linked oxidase domain protein
LOC77_RS14330	COG0247	lactate metabolic process
LOC77_RS14335	COG1966	Carbon starvation protein
LOC77_RS14340	COG3534	alpha-L-arabinofuranosidase
LOC77_RS14345	COG0395	ABC-type sugar transport system, permease component
LOC77_RS14350	COG1175	transmembrane transport
LOC77_RS14355	COG1653	transport
LOC77_RS14365	COG0647	UMP catabolic process
LOC77_RS14370	COG0235	Class ii aldolase
LOC77_RS14375	COG1069	ribulokinase activity
LOC77_RS14380	COG2160	L-arabinose isomerase activity
LOC77_RS14385	COG3507	Belongs to the glycosyl hydrolase 43 family
LOC77_RS14390	COG1363	Peptidase, m42
LOC77_RS14400	COG3326	Membrane
LOC77_RS14405	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LOC77_RS14415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LOC77_RS14420	COG1346	cytolysis
LOC77_RS14425	COG1380	Effector of murein hydrolase LrgA
LOC77_RS14430	COG3279	Response regulator of the LytR AlgR family
LOC77_RS14435	COG3275	phosphorelay sensor kinase activity
LOC77_RS14440	COG1011	Hydrolase
LOC77_RS14455	COG0398	Pfam SNARE associated Golgi protein
LOC77_RS14460	COG1484	DNA-dependent DNA replication
LOC77_RS14465	COG3611	Membrane attachment protein
LOC77_RS14480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LOC77_RS14485	COG1733	regulation of RNA biosynthetic process
LOC77_RS14490	COG2814	Major facilitator Superfamily
LOC77_RS14495	COG0656	L-ascorbic acid biosynthetic process
LOC77_RS14500	COG0237	dephospho-CoA kinase activity
LOC77_RS14505	COG1971	Probably functions as a manganese efflux pump
LOC77_RS14510	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LOC77_RS14515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LOC77_RS14515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LOC77_RS14520	COG5002	protein histidine kinase activity
LOC77_RS14525	COG0745	RESPONSE REGULATOR receiver
LOC77_RS14535	COG0538	isocitrate dehydrogenase activity
LOC77_RS14540	COG0372	Belongs to the citrate synthase family
LOC77_RS14570	COG0628	permease
LOC77_RS14575	COG3030	protein affecting phage T7 exclusion by the F plasmid
LOC77_RS14580	COG0469	pyruvate kinase activity
LOC77_RS14600	COG0281	malic enzyme
LOC77_RS14605	COG0587	DNA-directed DNA polymerase activity
LOC77_RS14625	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LOC77_RS14635	COG4109	DRTGG domain
LOC77_RS14645	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS14660	COG0521	Mo-molybdopterin cofactor biosynthetic process
LOC77_RS14670	COG0827	DNA restriction-modification system
LOC77_RS14675	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LOC77_RS14680	COG3874	Sporulation protein YtfJ
LOC77_RS14690	COG1714	RDD family
LOC77_RS14695	COG0616	signal peptide processing
LOC77_RS14700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LOC77_RS14705	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LOC77_RS14710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LOC77_RS14725	COG1104	cysteine desulfurase activity
LOC77_RS14730	COG1114	Component of the transport system for branched-chain amino acids
LOC77_RS14740	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LOC77_RS14745	COG1309	transcriptional regulator
LOC77_RS14750	COG1956	GAF domain-containing protein
LOC77_RS14755	COG2199	diguanylate cyclase activity
LOC77_RS14755	COG2203	Gaf domain
LOC77_RS14765	COG1012	belongs to the aldehyde dehydrogenase family
LOC77_RS14805	COG1017	nitric oxide dioxygenase activity
LOC77_RS14805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LOC77_RS14815	COG0693	protein deglycase activity
LOC77_RS14830	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LOC77_RS14835	COG1378	Sugar-specific transcriptional regulator TrmB
LOC77_RS14855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LOC77_RS14860	COG0454	-acetyltransferase
LOC77_RS14865	COG0517	IMP dehydrogenase activity
LOC77_RS14870	COG0123	including yeast histone deacetylase and acetoin utilization protein
LOC77_RS14875	COG1360	Flagellar Motor Protein
LOC77_RS14880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LOC77_RS14885	COG1609	Transcriptional regulator
LOC77_RS14890	COG1605	Chorismate mutase
LOC77_RS14890	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LOC77_RS14895	COG3118	belongs to the thioredoxin family
LOC77_RS14900	COG4980	gas vesicle protein
LOC77_RS14905	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LOC77_RS14915	COG1674	ftsk spoiiie
LOC77_RS14920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LOC77_RS14930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LOC77_RS14940	COG1363	Peptidase, m42
LOC77_RS14945	COG5584	Small secreted protein
LOC77_RS14950	COG0281	malic enzyme
LOC77_RS14955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LOC77_RS14970	COG0510	thiamine kinase activity
LOC77_RS14975	COG1597	lipid kinase activity
LOC77_RS14985	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LOC77_RS14990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LOC77_RS14995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LOC77_RS15000	COG2252	PERMEase
LOC77_RS15005	COG4473	ABC transporter
LOC77_RS15010	COG1131	(ABC) transporter
LOC77_RS15015	COG1349	DNA-binding transcription factor activity
LOC77_RS15020	COG1187	pseudouridine synthase activity
LOC77_RS15025	COG2244	polysaccharide biosynthetic process
LOC77_RS15030	COG2081	HI0933 family
LOC77_RS15035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LOC77_RS15045	COG1609	Transcriptional regulator
LOC77_RS15050	COG1653	transport
LOC77_RS15055	COG1175	transmembrane transport
LOC77_RS15060	COG0395	ABC-type sugar transport system, permease component
LOC77_RS15065	COG1486	melibiose metabolic process
LOC77_RS15075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LOC77_RS15090	COG2202	Pas domain
LOC77_RS15090	COG1366	Belongs to the anti-sigma-factor antagonist family
LOC77_RS15095	COG2814	Major facilitator Superfamily
LOC77_RS15100	COG5522	Integral membrane protein (intg_mem_TP0381)
LOC77_RS15105	COG0577	efflux transmembrane transporter activity
LOC77_RS15110	COG1136	(ABC) transporter
LOC77_RS15115	COG2205	protein histidine kinase activity
LOC77_RS15120	COG0745	RESPONSE REGULATOR receiver
LOC77_RS15125	COG0577	efflux transmembrane transporter activity
LOC77_RS15130	COG1136	(ABC) transporter
LOC77_RS15150	COG1131	(ABC) transporter
LOC77_RS15155	COG1725	Transcriptional regulator
LOC77_RS15170	COG1242	4 iron, 4 sulfur cluster binding
LOC77_RS15175	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LOC77_RS15185	COG0584	glycerophosphoryl diester phosphodiesterase
LOC77_RS15195	COG2267	carboxylic ester hydrolase activity
LOC77_RS15200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LOC77_RS15205	COG1113	amino acid transport
LOC77_RS15210	COG0367	asparagine synthase
LOC77_RS15230	COG1506	peptidase
LOC77_RS15235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LOC77_RS15240	COG1116	anion transmembrane transporter activity
LOC77_RS15245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LOC77_RS15250	COG0494	nUDIX hydrolase
LOC77_RS15255	COG4824	toxin secretion phage lysis holin
LOC77_RS15260	COG0783	Belongs to the Dps family
LOC77_RS15285	COG0288	reversible hydration of carbon dioxide
LOC77_RS15295	COG1271	oxidase subunit
LOC77_RS15300	COG1294	oxidase, subunit
LOC77_RS15310	COG4948	Mandelate Racemase Muconate Lactonizing
LOC77_RS15320	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LOC77_RS15325	COG0596	Alpha beta hydrolase
LOC77_RS15335	COG1169	isochorismate synthase
LOC77_RS15340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LOC77_RS15345	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LOC77_RS15470	COG3859	Proton-coupled thiamine transporter YuaJ
LOC77_RS15475	COG2268	Band 7 protein
LOC77_RS15480	COG1585	Membrane protein implicated in regulation of membrane protease activity
LOC77_RS15485	COG2318	DinB family
LOC77_RS15495	COG1454	alcohol dehydrogenase
LOC77_RS15500	COG1012	belongs to the aldehyde dehydrogenase family
LOC77_RS15505	COG1510	regulation of RNA biosynthetic process
LOC77_RS15515	COG0569	domain protein
LOC77_RS15520	COG1705	Flagellar rod assembly protein muramidase FlgJ
LOC77_RS15525	COG1017	nitric oxide dioxygenase activity
LOC77_RS15525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LOC77_RS15550	COG0628	permease
LOC77_RS15555	COG0673	inositol 2-dehydrogenase activity
LOC77_RS15560	COG0693	protein deglycase activity
LOC77_RS15565	COG0840	transmembrane signaling receptor activity
LOC77_RS15570	COG0840	transmembrane signaling receptor activity
LOC77_RS15575	COG0840	transmembrane signaling receptor activity
LOC77_RS15580	COG0840	transmembrane signaling receptor activity
LOC77_RS15595	COG2070	2-Nitropropane dioxygenase
LOC77_RS15600	COG0432	Pfam Uncharacterised protein family UPF0047
LOC77_RS15605	COG0366	Alpha amylase catalytic
LOC77_RS15610	COG1253	flavin adenine dinucleotide binding
LOC77_RS15615	COG2738	Putative neutral zinc metallopeptidase
LOC77_RS15630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LOC77_RS15655	COG1335	isochorismatase
LOC77_RS15660	COG1979	alcohol dehydrogenase
LOC77_RS15665	COG1979	alcohol dehydrogenase
LOC77_RS15670	COG2155	Conserved Protein
LOC77_RS15675	COG1098	S1 RNA binding domain
LOC77_RS15680	COG0436	Aminotransferase
LOC77_RS15685	COG1522	sequence-specific DNA binding
LOC77_RS15690	COG2267	carboxylic ester hydrolase activity
LOC77_RS15700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LOC77_RS15705	COG2205	protein histidine kinase activity
LOC77_RS15715	COG5018	Exonuclease
LOC77_RS15720	COG2814	Major facilitator Superfamily
LOC77_RS15725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LOC77_RS15730	COG3011	Protein conserved in bacteria
LOC77_RS15740	COG3290	protein histidine kinase activity
LOC77_RS15745	COG4565	transcriptional regulatory protein
LOC77_RS15750	COG1744	ABC transporter substrate-binding protein PnrA-like
LOC77_RS15755	COG3845	ABC transporter
LOC77_RS15760	COG4603	Belongs to the binding-protein-dependent transport system permease family
LOC77_RS15765	COG1079	Belongs to the binding-protein-dependent transport system permease family
LOC77_RS15775	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LOC77_RS15775	COG2111	Na H antiporter
LOC77_RS15780	COG2111	Na H antiporter
LOC77_RS15785	COG1006	Multisubunit Na H antiporter MnhC subunit
LOC77_RS15790	COG0651	ATP synthesis coupled electron transport
LOC77_RS15795	COG1863	multisubunit Na H antiporter MnhE subunit
LOC77_RS15800	COG2212	antiporter activity
LOC77_RS15805	COG1320	monovalent cation:proton antiporter activity
LOC77_RS15810	COG2050	protein possibly involved in aromatic compounds catabolism
LOC77_RS15815	COG2197	response regulator
LOC77_RS15830	COG0142	geranyltranstransferase activity
LOC77_RS15845	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LOC77_RS15850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LOC77_RS15855	COG1335	isochorismatase
LOC77_RS15860	COG5506	Protein of unknown function (DUF1694)
LOC77_RS15875	COG0628	permease
LOC77_RS15885	COG1418	mRNA catabolic process
LOC77_RS15890	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS15900	COG1511	domain protein
LOC77_RS15905	COG0433	COG0433 Predicted ATPase
LOC77_RS15905	COG1674	ftsk spoiiie
LOC77_RS15910	COG4499	WXG100 protein secretion system (Wss), protein YukC
LOC77_RS15915	COG5417	Belongs to the EsaB family
LOC77_RS15920	COG4842	Belongs to the WXG100 family
LOC77_RS15925	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LOC77_RS15925	COG2508	Transcriptional regulator
LOC77_RS15930	COG0686	Belongs to the AlaDH PNT family
LOC77_RS15935	COG5634	Uncharacterized conserved protein (DUF2278)
LOC77_RS15940	COG3251	PFAM MbtH domain protein
LOC77_RS15945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LOC77_RS15950	COG1535	isochorismatase
LOC77_RS15950	COG3433	isochorismatase activity
LOC77_RS15955	COG1021	2,3-dihydroxybenzoate-AMP ligase
LOC77_RS15960	COG1169	isochorismate synthase
LOC77_RS15965	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS15970	COG2819	hydrolase of the alpha beta superfamily
LOC77_RS15975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LOC77_RS15980	COG1268	BioY protein
LOC77_RS15985	COG2056	Na+-H+ antiporter family
LOC77_RS15995	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LOC77_RS16000	COG3584	3D domain protein
LOC77_RS16015	COG1252	NADH dehydrogenase
LOC77_RS16045	COG1131	(ABC) transporter
LOC77_RS16070	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LOC77_RS16075	COG0316	Belongs to the HesB IscA family
LOC77_RS16085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LOC77_RS16095	COG1252	NADH dehydrogenase
LOC77_RS16100	COG4837	Protein of unknown function (DUF1462)
LOC77_RS16105	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LOC77_RS16110	COG0823	Involved in the tonB-independent uptake of proteins
LOC77_RS16110	COG1506	peptidase
LOC77_RS16110	COG4946	Tricorn protease homolog
LOC77_RS16120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LOC77_RS16125	COG0460	homoserine dehydrogenase
LOC77_RS16130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LOC77_RS16135	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LOC77_RS16140	COG0647	UMP catabolic process
LOC77_RS16145	COG2445	Protein of unknown function DUF86
LOC77_RS16150	COG4470	Protein conserved in bacteria
LOC77_RS16160	COG0739	heme binding
LOC77_RS16170	COG0737	Belongs to the 5'-nucleotidase family
LOC77_RS16175	COG0730	response to heat
LOC77_RS16180	COG1801	Protein of unknown function DUF72
LOC77_RS16195	COG2508	Transcriptional regulator
LOC77_RS16215	COG2814	Major facilitator Superfamily
LOC77_RS16220	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LOC77_RS16225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LOC77_RS16230	COG2356	endonuclease I
LOC77_RS16235	COG3842	ATPase activity
LOC77_RS16240	COG2188	Transcriptional regulator
LOC77_RS16245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LOC77_RS16250	COG0395	ABC-type sugar transport system, permease component
LOC77_RS16255	COG1175	transmembrane transport
LOC77_RS16260	COG1653	transport
LOC77_RS16265	COG2222	sugar isomerase
LOC77_RS16275	COG0322	excinuclease ABC activity
LOC77_RS16280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LOC77_RS16290	COG3409	Peptidoglycan-binding domain 1 protein
LOC77_RS16295	COG0719	Fe-S assembly protein
LOC77_RS16300	COG0822	iron-sulfur transferase activity
LOC77_RS16305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LOC77_RS16310	COG0719	Fe-S assembly protein
LOC77_RS16315	COG0396	ATPase activity
LOC77_RS16325	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LOC77_RS16330	COG1464	Belongs to the NlpA lipoprotein family
LOC77_RS16335	COG2011	ABC-type metal ion transport system permease component
LOC77_RS16340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LOC77_RS16350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LOC77_RS16355	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LOC77_RS16370	COG1393	Belongs to the ArsC family
LOC77_RS16375	COG1960	acyl-CoA dehydrogenase activity
LOC77_RS16380	COG0183	Belongs to the thiolase family
LOC77_RS16385	COG1024	Enoyl-CoA hydratase
LOC77_RS16385	COG1250	3-hydroxyacyl-CoA dehydrogenase
LOC77_RS16405	COG5577	PFAM Coat F domain
LOC77_RS16410	COG1846	Transcriptional regulator
LOC77_RS16415	COG0477	Major facilitator Superfamily
LOC77_RS16420	COG0583	DNA-binding transcription factor activity
LOC77_RS16440	COG1120	ATPase activity
LOC77_RS16455	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS16460	COG0783	Belongs to the Dps family
LOC77_RS16465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOC77_RS16470	COG0745	RESPONSE REGULATOR receiver
LOC77_RS16475	COG2770	Histidine kinase
LOC77_RS16475	COG2205	protein histidine kinase activity
LOC77_RS16485	COG1309	transcriptional regulator
LOC77_RS16490	COG0114	fumarate hydratase activity
LOC77_RS16500	COG0697	spore germination
LOC77_RS16505	COG0814	amino acid
LOC77_RS16515	COG2197	response regulator
LOC77_RS16520	COG4585	Histidine kinase
LOC77_RS16525	COG4758	membrane
LOC77_RS16530	COG3595	metallopeptidase activity
LOC77_RS16535	COG1842	Phage shock protein A
LOC77_RS16540	COG4758	membrane
LOC77_RS16545	COG2814	Major facilitator Superfamily
LOC77_RS16550	COG2096	Adenosyltransferase
LOC77_RS16555	COG1120	ATPase activity
LOC77_RS16560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOC77_RS16565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LOC77_RS16570	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS16575	COG3386	PFAM SMP-30 Gluconolaconase
LOC77_RS16580	COG2205	protein histidine kinase activity
LOC77_RS16585	COG0745	RESPONSE REGULATOR receiver
LOC77_RS16595	COG1191	sigma factor activity
LOC77_RS16605	COG2140	Oxalate decarboxylase
LOC77_RS16615	COG1120	ATPase activity
LOC77_RS16620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOC77_RS16625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOC77_RS16630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LOC77_RS16635	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LOC77_RS16640	COG0531	amino acid
LOC77_RS16650	COG1988	membrane-bound metal-dependent
LOC77_RS16655	COG1368	sulfuric ester hydrolase activity
LOC77_RS16660	COG1910	domain protein
LOC77_RS16665	COG0725	ABC transporter, periplasmic molybdate-binding protein
LOC77_RS16670	COG4149	molybdate abc transporter
LOC77_RS16675	COG2197	response regulator
LOC77_RS16680	COG3850	Histidine kinase
LOC77_RS16685	COG1131	(ABC) transporter
LOC77_RS16695	COG0842	Transport permease protein
LOC77_RS16700	COG0656	L-ascorbic acid biosynthetic process
LOC77_RS16720	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LOC77_RS16725	COG3973	AAA domain
LOC77_RS16730	COG2860	membrane
LOC77_RS16740	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LOC77_RS16745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LOC77_RS16750	COG2217	Heavy metal translocating P-type atpase
LOC77_RS16755	COG2217	Heavy metal translocating P-type atpase
LOC77_RS16760	COG2608	mercury ion transmembrane transporter activity
LOC77_RS16765	COG1937	Protein conserved in bacteria
LOC77_RS16770	COG0673	inositol 2-dehydrogenase activity
LOC77_RS16780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOC77_RS16785	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LOC77_RS16790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOC77_RS16795	COG1126	abc transporter atp-binding protein
LOC77_RS16800	COG0765	amino acid transport
LOC77_RS16805	COG0765	amino acid transport
LOC77_RS16810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LOC77_RS16815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LOC77_RS16820	COG0454	-acetyltransferase
LOC77_RS16825	COG0583	DNA-binding transcription factor activity
LOC77_RS16830	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS16835	COG2732	(Barnase) inhibitor
LOC77_RS16850	COG0557	exoribonuclease II activity
LOC77_RS16855	COG1647	Serine aminopeptidase, S33
LOC77_RS16860	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LOC77_RS16865	COG1476	TRANSCRIPTIONal
LOC77_RS16870	COG1396	sequence-specific DNA binding
LOC77_RS16875	COG1396	sequence-specific DNA binding
LOC77_RS16880	COG1733	regulation of RNA biosynthetic process
LOC77_RS16905	COG1131	(ABC) transporter
LOC77_RS16910	COG1174	glycine betaine transport
LOC77_RS16915	COG1732	Glycine betaine
LOC77_RS16920	COG1174	glycine betaine transport
LOC77_RS16925	COG0517	IMP dehydrogenase activity
LOC77_RS16925	COG1125	glycine betaine transport
LOC77_RS16930	COG1510	regulation of RNA biosynthetic process
LOC77_RS16935	COG1174	glycine betaine transport
LOC77_RS16940	COG1732	Glycine betaine
LOC77_RS16945	COG1174	glycine betaine transport
LOC77_RS16950	COG0517	IMP dehydrogenase activity
LOC77_RS16950	COG1125	glycine betaine transport
LOC77_RS16955	COG1510	regulation of RNA biosynthetic process
LOC77_RS16960	COG2095	MarC family integral membrane protein
LOC77_RS16965	COG3064	Membrane
LOC77_RS16970	COG4640	response to antibiotic
LOC77_RS16975	COG0456	acetyltransferase
LOC77_RS16990	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LOC77_RS17005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LOC77_RS17010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LOC77_RS17015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LOC77_RS17025	COG2234	aminopeptidase activity
LOC77_RS17045	COG0126	phosphoglycerate kinase activity
LOC77_RS17050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LOC77_RS17055	COG2390	Transcriptional regulator
LOC77_RS17060	COG2814	Major facilitator Superfamily
LOC77_RS17065	COG1609	Transcriptional regulator
LOC77_RS17070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOC77_RS17080	COG0583	DNA-binding transcription factor activity
LOC77_RS17085	COG0697	spore germination
LOC77_RS17090	COG1113	amino acid transport
LOC77_RS17095	COG1737	Transcriptional regulator
LOC77_RS17100	COG1070	Carbohydrate kinase
LOC77_RS17125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LOC77_RS17130	COG2186	Transcriptional regulator
LOC77_RS17135	COG1620	l-lactate permease
LOC77_RS17140	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LOC77_RS17150	COG5039	Polysaccharide pyruvyl transferase
LOC77_RS17155	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LOC77_RS17160	COG0110	maltose O-acetyltransferase activity
LOC77_RS17165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LOC77_RS17170	COG2244	polysaccharide biosynthetic process
LOC77_RS17175	COG1216	Glycosyl transferase, family 2
LOC77_RS17180	COG5039	Polysaccharide pyruvyl transferase
LOC77_RS17185	COG1216	Glycosyl transferase, family 2
LOC77_RS17195	COG0438	transferase activity, transferring glycosyl groups
LOC77_RS17200	COG1215	transferase activity, transferring glycosyl groups
LOC77_RS17205	COG0438	transferase activity, transferring glycosyl groups
LOC77_RS17210	COG1086	Polysaccharide biosynthesis protein
LOC77_RS17215	COG0489	protein tyrosine kinase activity
LOC77_RS17220	COG3944	biosynthesis protein
LOC77_RS17225	COG1396	sequence-specific DNA binding
LOC77_RS17230	COG2272	Belongs to the type-B carboxylesterase lipase family
LOC77_RS17240	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LOC77_RS17245	COG2364	Membrane
LOC77_RS17250	COG0456	acetyltransferase
LOC77_RS17255	COG3479	Phenolic acid decarboxylase
LOC77_RS17300	COG2223	nitrite transmembrane transporter activity
LOC77_RS17305	COG1609	Transcriptional regulator
LOC77_RS17315	COG0583	DNA-binding transcription factor activity
LOC77_RS17320	COG2828	Protein conserved in bacteria
LOC77_RS17325	COG0477	Major facilitator Superfamily
LOC77_RS17325	COG2814	Major facilitator Superfamily
LOC77_RS17330	COG1611	Belongs to the LOG family
LOC77_RS17335	COG1694	Mazg nucleotide pyrophosphohydrolase
LOC77_RS17340	COG0659	secondary active sulfate transmembrane transporter activity
LOC77_RS17345	COG0288	reversible hydration of carbon dioxide
LOC77_RS17350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOC77_RS17355	COG4290	ribonuclease
LOC77_RS17360	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LOC77_RS17365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOC77_RS17375	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LOC77_RS17385	COG1051	belongs to the nudix hydrolase family
LOC77_RS17390	COG0492	ferredoxin-NADP+ reductase activity
LOC77_RS17395	COG3883	PFAM NLP P60 protein
LOC77_RS17395	COG0791	NLP P60 protein
LOC77_RS17400	COG0457	Tetratricopeptide repeat
LOC77_RS17405	COG5002	protein histidine kinase activity
LOC77_RS17410	COG0745	RESPONSE REGULATOR receiver
LOC77_RS17420	COG1132	(ABC) transporter
LOC77_RS17425	COG0140	phosphoribosyl-ATP diphosphatase activity
LOC77_RS17425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LOC77_RS17450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LOC77_RS17465	COG4990	cell redox homeostasis
LOC77_RS17470	COG0110	maltose O-acetyltransferase activity
LOC77_RS17490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LOC77_RS17500	COG2188	Transcriptional regulator
LOC77_RS17505	COG1309	transcriptional regulator
LOC77_RS17510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LOC77_RS17515	COG1950	PFAM Membrane protein of
LOC77_RS17520	COG1983	PspC domain protein
LOC77_RS17525	COG3595	metallopeptidase activity
LOC77_RS17540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LOC77_RS17550	COG4897	Protein conserved in bacteria
LOC77_RS17555	COG0574	Belongs to the PEP-utilizing enzyme family
LOC77_RS17555	COG3848	Pyruvate phosphate dikinase
LOC77_RS17560	COG1309	transcriptional regulator
LOC77_RS17565	COG2814	Major facilitator Superfamily
LOC77_RS17575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOC77_RS17585	COG3409	Peptidoglycan-binding domain 1 protein
LOC77_RS17585	COG0793	Belongs to the peptidase S41A family
LOC77_RS17590	COG3420	alginic acid biosynthetic process
LOC77_RS17595	COG2177	Part of the ABC transporter FtsEX involved in
LOC77_RS17600	COG2884	Cell division ATP-binding protein ftsE
LOC77_RS17605	COG2010	Cytochrome c
LOC77_RS17610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOC77_RS17625	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LOC77_RS17640	COG1516	flagellar protein fliS
LOC77_RS17645	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LOC77_RS17650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LOC77_RS17670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LOC77_RS17675	COG1256	bacterial-type flagellum assembly
LOC77_RS17675	COG4786	Flagellar basal body rod
LOC77_RS17680	COG3418	PFAM FlgN family protein
LOC77_RS17685	COG2747	anti-sigma28 factor FlgM
LOC77_RS17695	COG1040	competence protein
LOC77_RS17705	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LOC77_RS17710	COG1307	EDD domain protein, DegV family
LOC77_RS17715	COG2197	response regulator
LOC77_RS17720	COG4585	Histidine kinase
LOC77_RS17725	COG1739	Uncharacterized protein family UPF0029
LOC77_RS17730	COG1316	TRANSCRIPTIONal
LOC77_RS17735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LOC77_RS17740	COG0438	transferase activity, transferring glycosyl groups
LOC77_RS17745	COG1215	transferase activity, transferring glycosyl groups
LOC77_RS17750	COG3206	protein involved in exopolysaccharide biosynthesis
LOC77_RS17755	COG3307	-O-antigen
LOC77_RS17760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LOC77_RS17765	COG0297	glycogen (starch) synthase activity
LOC77_RS17765	COG0438	transferase activity, transferring glycosyl groups
LOC77_RS17770	COG2244	polysaccharide biosynthetic process
LOC77_RS17780	COG2247	cell wall binding repeat
LOC77_RS17780	COG0860	N-Acetylmuramoyl-L-alanine amidase
LOC77_RS17785	COG2247	cell wall binding repeat
LOC77_RS17785	COG2385	sporulation resulting in formation of a cellular spore
LOC77_RS17795	COG1316	TRANSCRIPTIONal
LOC77_RS17800	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LOC77_RS17805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LOC77_RS17810	COG1134	teichoic acid transport
LOC77_RS17815	COG1682	transport, permease protein
LOC77_RS17820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LOC77_RS17830	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LOC77_RS17835	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LOC77_RS17840	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LOC77_RS17845	COG4193	domain, Protein
LOC77_RS17850	COG1482	cell wall glycoprotein biosynthetic process
LOC77_RS17855	COG0697	spore germination
LOC77_RS17860	COG0814	amino acid
LOC77_RS17870	COG1215	transferase activity, transferring glycosyl groups
LOC77_RS17875	COG2814	Major facilitator Superfamily
LOC77_RS17880	COG1316	TRANSCRIPTIONal
LOC77_RS17885	COG0561	phosphatase activity
LOC77_RS17890	COG2433	Pfam Transposase IS66
LOC77_RS17895	COG0791	NLP P60 protein
LOC77_RS17905	COG2843	Capsule synthesis protein
LOC77_RS17915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LOC77_RS17920	COG0697	spore germination
LOC77_RS17925	COG0814	amino acid
LOC77_RS17935	COG1609	Transcriptional regulator
LOC77_RS17940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LOC77_RS17950	COG1129	ABC transporter
LOC77_RS17955	COG1172	Belongs to the binding-protein-dependent transport system permease family
LOC77_RS17960	COG1879	ABC-type sugar transport system periplasmic component
LOC77_RS17965	COG3103	Sh3 type 3 domain protein
LOC77_RS17970	COG2249	NAD(P)H dehydrogenase (quinone) activity
LOC77_RS17975	COG3527	Alpha-acetolactate decarboxylase
LOC77_RS17980	COG0028	Belongs to the TPP enzyme family
LOC77_RS17985	COG0583	DNA-binding transcription factor activity
LOC77_RS17990	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LOC77_RS18005	COG5337	Spore coat protein CotH
LOC77_RS18015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LOC77_RS18030	COG1522	sequence-specific DNA binding
LOC77_RS18035	COG2059	Chromate
LOC77_RS18040	COG2059	Chromate
LOC77_RS18050	COG0655	NAD(P)H dehydrogenase (quinone) activity
LOC77_RS18055	COG0583	DNA-binding transcription factor activity
LOC77_RS18090	COG5444	nuclease activity
LOC77_RS18105	COG3878	Protein conserved in bacteria
LOC77_RS18110	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LOC77_RS18115	COG4464	protein tyrosine phosphatase activity
LOC77_RS18120	COG0489	protein tyrosine kinase activity
LOC77_RS18125	COG3944	biosynthesis protein
LOC77_RS18135	COG4715	Zinc finger, swim domain protein
LOC77_RS18140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LOC77_RS18145	COG0561	phosphatase activity
LOC77_RS18150	COG1349	DNA-binding transcription factor activity
LOC77_RS18155	COG0629	single-stranded DNA binding
LOC77_RS18180	COG0457	Tetratricopeptide repeat
LOC77_RS18185	COG4786	Flagellar basal body rod
LOC77_RS18190	COG4786	Flagellar basal body rod
LOC77_RS18195	COG1077	Cell shape determining protein MreB Mrl
LOC77_RS18200	COG1609	Transcriptional regulator
LOC77_RS18205	COG1846	Transcriptional regulator
LOC77_RS18210	COG2814	Major facilitator Superfamily
LOC77_RS18215	COG1953	Uracil, thiamine, allantoin
LOC77_RS18220	COG0477	Major facilitator Superfamily
LOC77_RS18225	COG1335	isochorismatase
LOC77_RS18230	COG0004	ammonium transporteR
LOC77_RS18235	COG0347	Belongs to the P(II) protein family
LOC77_RS18240	COG0772	Belongs to the SEDS family
LOC77_RS18245	COG0671	phosphoesterase, PA-phosphatase related
LOC77_RS18255	COG0739	heme binding
LOC77_RS18260	COG1247	-acetyltransferase
LOC77_RS18275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOC77_RS18290	COG0726	polysaccharide deacetylase
LOC77_RS18300	COG1959	2 iron, 2 sulfur cluster binding
LOC77_RS18315	COG0831	urea catabolic process
LOC77_RS18320	COG3237	CsbD-like
LOC77_RS18325	COG1994	Peptidase M50
LOC77_RS18330	COG0457	Tetratricopeptide repeat
LOC77_RS18340	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LOC77_RS18350	COG2304	oxidoreductase activity
LOC77_RS18355	COG2304	oxidoreductase activity
LOC77_RS18360	COG2385	sporulation resulting in formation of a cellular spore
LOC77_RS18365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LOC77_RS18375	COG4836	Membrane
LOC77_RS18445	COG0698	ribose 5-phosphate isomerase
LOC77_RS18450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LOC77_RS18460	COG0009	L-threonylcarbamoyladenylate synthase
LOC77_RS18465	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LOC77_RS18485	COG2890	protein-(glutamine-N5) methyltransferase activity
LOC77_RS18490	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LOC77_RS18495	COG0346	lactoylglutathione lyase activity
LOC77_RS18500	COG0789	Transcriptional regulator
LOC77_RS18505	COG0679	Auxin Efflux Carrier
LOC77_RS18510	COG0281	malic enzyme
LOC77_RS18525	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LOC77_RS18535	COG1494	fructose-1,6-bisphosphatase
LOC77_RS18540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LOC77_RS18550	COG0191	fructose-bisphosphate aldolase activity
LOC77_RS18555	COG2204	response regulator
LOC77_RS18560	COG4821	SIS domain
LOC77_RS18575	COG2181	nitrate reductase activity
LOC77_RS18575	COG0247	lactate metabolic process
LOC77_RS18580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOC77_RS18595	COG1132	(ABC) transporter
LOC77_RS18600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOC77_RS18610	COG2181	nitrate reductase activity
LOC77_RS18615	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LOC77_RS18620	COG1140	nitrate reductase beta subunit
LOC77_RS18625	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LOC77_RS18630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LOC77_RS18640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LOC77_RS18645	COG2223	nitrite transmembrane transporter activity
LOC77_RS18655	COG4506	Protein conserved in bacteria
LOC77_RS18660	COG0457	Tetratricopeptide repeat
LOC77_RS18700	COG0010	Belongs to the arginase family
LOC77_RS18705	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LOC77_RS18710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LOC77_RS18725	COG1994	Peptidase M50
LOC77_RS18730	COG1942	4-Oxalocrotonate Tautomerase
LOC77_RS18735	COG1846	Transcriptional regulator
LOC77_RS18740	COG0531	amino acid
LOC77_RS18745	COG3465	dGTPase activity
LOC77_RS18750	COG1078	dGTPase activity
LOC77_RS18765	COG1695	Transcriptional regulator
LOC77_RS18775	COG1131	(ABC) transporter
LOC77_RS18780	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LOC77_RS18810	COG0583	DNA-binding transcription factor activity
LOC77_RS18815	COG2855	membrane
LOC77_RS18820	COG0280	phosphate acetyltransferase
LOC77_RS18830	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS18835	COG0436	Aminotransferase
LOC77_RS18865	COG2814	Major facilitator Superfamily
LOC77_RS18870	COG2814	Major facilitator Superfamily
LOC77_RS18875	COG0833	amino acid
LOC77_RS18880	COG4187	Peptidase family M20/M25/M40
LOC77_RS18885	COG1012	belongs to the aldehyde dehydrogenase family
LOC77_RS18890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LOC77_RS18900	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LOC77_RS18905	COG1091	dTDP-4-dehydrorhamnose reductase activity
LOC77_RS18910	COG1088	dTDP-glucose 4,6-dehydratase activity
LOC77_RS18915	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LOC77_RS18920	COG3980	spore coat polysaccharide biosynthesis protein
LOC77_RS18925	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
LOC77_RS18930	COG2089	acid synthase
LOC77_RS18935	COG0456	acetyltransferase
LOC77_RS18940	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LOC77_RS18945	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LOC77_RS18950	COG0463	Glycosyl transferase, family 2
LOC77_RS18960	COG2363	Small membrane protein
LOC77_RS18965	COG2233	PERMEase
LOC77_RS18980	COG1216	Glycosyl transferase, family 2
LOC77_RS18995	COG1695	Transcriptional regulator
LOC77_RS19000	COG0351	phosphomethylpyrimidine kinase
LOC77_RS19010	COG1621	beta-fructofuranosidase activity
LOC77_RS19015	COG1263	PTS System
LOC77_RS19015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LOC77_RS19020	COG3711	transcriptional antiterminator
LOC77_RS19030	COG1404	Belongs to the peptidase S8 family
LOC77_RS19035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOC77_RS19040	COG0778	Nitroreductase
LOC77_RS19045	COG0772	Belongs to the SEDS family
LOC77_RS19050	COG0454	-acetyltransferase
LOC77_RS19070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LOC77_RS19075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LOC77_RS19080	COG2261	transglycosylase associated protein
LOC77_RS19085	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LOC77_RS19095	COG2246	polysaccharide biosynthetic process
LOC77_RS19100	COG1309	transcriptional regulator
LOC77_RS19120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LOC77_RS19125	COG2837	iron assimilation
LOC77_RS19145	COG0583	DNA-binding transcription factor activity
LOC77_RS19155	COG1346	cytolysis
LOC77_RS19160	COG4895	conserved protein (DUF2196)
LOC77_RS19165	COG0789	Transcriptional regulator
LOC77_RS19170	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LOC77_RS19175	COG0346	lactoylglutathione lyase activity
LOC77_RS19180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOC77_RS19185	COG1404	Belongs to the peptidase S8 family
LOC77_RS19190	COG1442	glycosyl transferase family 8
LOC77_RS19195	COG1846	Transcriptional regulator
LOC77_RS19200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LOC77_RS19205	COG2357	RelA SpoT domain protein
LOC77_RS19210	COG1575	Belongs to the MenA family. Type 1 subfamily
LOC77_RS19225	COG1696	Membrane protein involved in D-alanine export
LOC77_RS19235	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LOC77_RS19240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LOC77_RS19245	COG1486	melibiose metabolic process
LOC77_RS19250	COG1447	Phosphotransferase system cellobiose-specific component IIA
LOC77_RS19255	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOC77_RS19260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOC77_RS19265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LOC77_RS19265	COG3711	transcriptional antiterminator
LOC77_RS19275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOC77_RS19280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOC77_RS19290	COG0640	Transcriptional regulator
LOC77_RS19295	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LOC77_RS19300	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOC77_RS19305	COG1447	Phosphotransferase system cellobiose-specific component IIA
LOC77_RS19310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LOC77_RS19315	COG2723	6-phospho-beta-galactosidase activity
LOC77_RS19320	COG1940	carbohydrate kinase activity
LOC77_RS19325	COG1482	cell wall glycoprotein biosynthetic process
LOC77_RS19335	COG0753	catalase activity
LOC77_RS19340	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LOC77_RS19345	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LOC77_RS19350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LOC77_RS19355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LOC77_RS19360	COG4988	ABC transporter
LOC77_RS19365	COG1294	oxidase, subunit
LOC77_RS19370	COG1271	oxidase subunit
LOC77_RS19375	COG3493	citrate carrier protein
LOC77_RS19380	COG0726	polysaccharide deacetylase
LOC77_RS19385	COG3842	ATPase activity
LOC77_RS19390	COG2508	Transcriptional regulator
LOC77_RS19395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOC77_RS19405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LOC77_RS19420	COG4894	glucomannan catabolic process
LOC77_RS19425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LOC77_RS19430	COG0500	methyltransferase
LOC77_RS19435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LOC77_RS19450	COG0753	catalase activity
LOC77_RS19450	COG0693	protein deglycase activity
LOC77_RS19455	COG2851	Citrate transporter
LOC77_RS19460	COG2273	Hydrolase Family 16
LOC77_RS19470	COG2270	Major facilitator Superfamily
LOC77_RS19475	COG0513	Belongs to the DEAD box helicase family
LOC77_RS19580	COG0697	spore germination
LOC77_RS19585	COG0589	response to stress
LOC77_RS19650	COG3507	Belongs to the glycosyl hydrolase 43 family
LOC77_RS19675	COG0010	Belongs to the arginase family
LOC77_RS19680	COG0833	amino acid
LOC77_RS19685	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LOC77_RS19690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LOC77_RS19700	COG2390	Transcriptional regulator
LOC77_RS19705	COG0561	phosphatase activity
LOC77_RS19735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LOC77_RS19740	COG5294	Protein conserved in bacteria
LOC77_RS19745	COG0577	efflux transmembrane transporter activity
LOC77_RS19750	COG1136	(ABC) transporter
LOC77_RS19755	COG2205	protein histidine kinase activity
LOC77_RS19760	COG0745	RESPONSE REGULATOR receiver
LOC77_RS19775	COG1082	Xylose isomerase domain protein TIM barrel
LOC77_RS19785	COG2814	Major facilitator Superfamily
LOC77_RS19815	COG1349	DNA-binding transcription factor activity
LOC77_RS19820	COG0667	Aldo Keto reductase
LOC77_RS19825	COG2814	Major facilitator Superfamily
LOC77_RS19840	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS19845	COG2197	response regulator
LOC77_RS19850	COG4585	Histidine kinase
LOC77_RS19855	COG3239	Fatty acid desaturase
LOC77_RS19860	COG1309	transcriptional regulator
LOC77_RS19865	COG1012	belongs to the aldehyde dehydrogenase family
LOC77_RS19870	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LOC77_RS19880	COG0640	Transcriptional regulator
LOC77_RS19885	COG2814	Major facilitator Superfamily
LOC77_RS19890	COG1714	RDD family
LOC77_RS19905	COG0501	Belongs to the peptidase M48B family
LOC77_RS19910	COG1715	Restriction endonuclease
LOC77_RS19915	COG0450	alkyl hydroperoxide reductase
LOC77_RS19920	COG3634	alkyl hydroperoxide reductase activity
LOC77_RS19925	COG1113	amino acid transport
LOC77_RS19935	COG2080	2 iron, 2 sulfur cluster binding
LOC77_RS19950	COG2068	MobA-Related Protein
LOC77_RS19955	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LOC77_RS19975	COG1192	Involved in chromosome partitioning
LOC77_RS20010	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LOC77_RS20020	COG0456	acetyltransferase
LOC77_RS20025	COG0457	Tetratricopeptide repeat
LOC77_RS20030	COG0010	Belongs to the arginase family
LOC77_RS20035	COG0833	amino acid
LOC77_RS20040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LOC77_RS20045	COG3829	transcription factor binding
LOC77_RS20055	COG0488	(ABC) transporter
LOC77_RS20070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LOC77_RS20075	COG3850	Histidine kinase
LOC77_RS20075	COG5002	protein histidine kinase activity
LOC77_RS20085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOC77_RS20090	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LOC77_RS20095	COG4853	Protein conserved in bacteria
LOC77_RS20100	COG4863	YycH protein
LOC77_RS20105	COG5002	protein histidine kinase activity
LOC77_RS20110	COG0745	RESPONSE REGULATOR receiver
LOC77_RS20140	COG0346	lactoylglutathione lyase activity
LOC77_RS20145	COG0305	Participates in initiation and elongation during chromosome replication
LOC77_RS20160	COG3093	addiction module antidote protein HigA
LOC77_RS20165	COG0297	glycogen (starch) synthase activity
LOC77_RS20175	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LOC77_RS20180	COG0438	transferase activity, transferring glycosyl groups
LOC77_RS20190	COG0515	serine threonine protein kinase
LOC77_RS20200	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LOC77_RS20205	COG4241	membrane
LOC77_RS20215	COG5577	PFAM Coat F domain
LOC77_RS20220	COG1733	regulation of RNA biosynthetic process
LOC77_RS20230	COG0697	spore germination
LOC77_RS20235	COG1621	beta-fructofuranosidase activity
LOC77_RS20240	COG1621	beta-fructofuranosidase activity
LOC77_RS20245	COG1802	Transcriptional regulator
LOC77_RS20250	COG2318	DinB family
LOC77_RS20255	COG2211	Major facilitator Superfamily
LOC77_RS20265	COG0778	Nitroreductase
LOC77_RS20270	COG1846	Transcriptional regulator
LOC77_RS20275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOC77_RS20280	COG1846	Transcriptional regulator
LOC77_RS20295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LOC77_RS20300	COG0583	DNA-binding transcription factor activity
LOC77_RS20305	COG1028	Short-chain dehydrogenase reductase Sdr
LOC77_RS20310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LOC77_RS20315	COG0697	spore germination
LOC77_RS20325	COG1959	2 iron, 2 sulfur cluster binding
LOC77_RS20340	COG1331	Highly conserved protein containing a thioredoxin domain
LOC77_RS20345	COG1266	CAAX protease self-immunity
LOC77_RS20350	COG2814	Major facilitator Superfamily
LOC77_RS20350	COG0477	Major facilitator Superfamily
LOC77_RS20355	COG0346	lactoylglutathione lyase activity
LOC77_RS20360	COG1609	Transcriptional regulator
LOC77_RS20365	COG0708	Exodeoxyribonuclease III
LOC77_RS20370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LOC77_RS20375	COG2169	Transcriptional regulator
LOC77_RS20385	COG0629	single-stranded DNA binding
LOC77_RS20395	COG0012	GTP binding
LOC77_RS20400	COG0243	molybdopterin cofactor binding
LOC77_RS20405	COG4481	Protein conserved in bacteria
LOC77_RS20410	COG3949	Membrane
LOC77_RS20425	COG1475	DNA binding
LOC77_RS20430	COG1192	Involved in chromosome partitioning
LOC77_RS20455	COG1847	R3H domain protein
LOC77_RS20460	COG0706	membrane insertase activity