locus-tag	class	description
GPY14_RS00010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY14_RS00015	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPY14_RS00020	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY14_RS00020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY14_RS00025	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPY14_RS00050	COG1285	pathogenesis
GPY14_RS00065	COG2205	protein histidine kinase activity
GPY14_RS00080	COG2427	Protein of unknown function (DUF1641)
GPY14_RS00085	COG2124	cytochrome p450
GPY14_RS00090	COG1819	glycosyl
GPY14_RS00105	COG0390	transport system, permease component
GPY14_RS00110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY14_RS00115	COG0697	spore germination
GPY14_RS00120	COG4297	protein containing double-stranded beta helix domain
GPY14_RS00130	COG1252	NADH dehydrogenase
GPY14_RS00140	COG2211	Major facilitator Superfamily
GPY14_RS00145	COG1609	Transcriptional regulator
GPY14_RS00150	COG0246	Mannitol dehydrogenase
GPY14_RS00155	COG2721	sulfolactate sulfo-lyase activity
GPY14_RS00160	COG0730	response to heat
GPY14_RS00165	COG2318	DinB family
GPY14_RS00170	COG0457	Tetratricopeptide repeat
GPY14_RS00180	COG3409	Peptidoglycan-binding domain 1 protein
GPY14_RS00180	COG1388	LysM domain
GPY14_RS00180	COG5632	N-Acetylmuramoyl-L-alanine amidase
GPY14_RS00190	COG4195	phage-related replication protein
GPY14_RS00195	COG2856	Zn peptidase
GPY14_RS00200	COG1396	sequence-specific DNA binding
GPY14_RS00210	COG1522	sequence-specific DNA binding
GPY14_RS00215	COG1484	DNA-dependent DNA replication
GPY14_RS00230	COG1595	DNA-templated transcription, initiation
GPY14_RS00235	COG3728	DNA packaging
GPY14_RS00235	COG5484	DNA packaging
GPY14_RS00240	COG1783	phage Terminase large subunit
GPY14_RS00245	COG5518	Phage portal protein
GPY14_RS00250	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPY14_RS00255	COG4653	Phage capsid family
GPY14_RS00305	COG3953	SLT domain
GPY14_RS00305	COG5412	phage tail tape measure protein
GPY14_RS00305	COG5412	phage tail tape measure protein
GPY14_RS00305	COG3953	SLT domain
GPY14_RS00305	COG3953	SLT domain
GPY14_RS00305	COG5412	phage tail tape measure protein
GPY14_RS00310	COG1652	LysM domain
GPY14_RS00315	COG4193	domain, Protein
GPY14_RS00325	COG3628	GPW Gp25 family protein
GPY14_RS00330	COG3299	homolog of phage Mu protein gp47
GPY14_RS00335	COG3778	Protein conserved in bacteria
GPY14_RS00375	COG5632	N-Acetylmuramoyl-L-alanine amidase
GPY14_RS00375	COG3409	Peptidoglycan-binding domain 1 protein
GPY14_RS00390	COG0306	phosphate transporter
GPY14_RS00395	COG1392	Phosphate transport regulator
GPY14_RS00400	COG0531	amino acid
GPY14_RS00405	COG0346	lactoylglutathione lyase activity
GPY14_RS00410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GPY14_RS00415	COG0463	Glycosyl transferase, family 2
GPY14_RS00420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY14_RS00425	COG0477	Major facilitator Superfamily
GPY14_RS00430	COG2362	D-Aminopeptidase
GPY14_RS00435	COG0601	transmembrane transport
GPY14_RS00440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY14_RS00445	COG0444	Belongs to the ABC transporter superfamily
GPY14_RS00450	COG4166	transmembrane transport
GPY14_RS00455	COG1619	proteins homologs of microcin C7 resistance protein MccF
GPY14_RS00460	COG4948	Mandelate Racemase Muconate Lactonizing
GPY14_RS00465	COG0791	NLP P60 protein
GPY14_RS00470	COG4608	Belongs to the ABC transporter superfamily
GPY14_RS00475	COG2706	6-phosphogluconolactonase activity
GPY14_RS00480	COG1834	amidinotransferase
GPY14_RS00485	COG1607	acyl-coa hydrolase
GPY14_RS00490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY14_RS00495	COG2076	Multidrug Resistance protein
GPY14_RS00505	COG0788	formyltetrahydrofolate deformylase activity
GPY14_RS00510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPY14_RS00520	COG1764	response to oxidative stress
GPY14_RS00525	COG1846	Transcriptional regulator
GPY14_RS00530	COG1764	response to oxidative stress
GPY14_RS00545	COG0463	Glycosyl transferase, family 2
GPY14_RS00545	COG0457	Tetratricopeptide repeat
GPY14_RS00555	COG2814	Major facilitator Superfamily
GPY14_RS00560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY14_RS00570	COG1404	Belongs to the peptidase S8 family
GPY14_RS00575	COG1366	Belongs to the anti-sigma-factor antagonist family
GPY14_RS00580	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPY14_RS00585	COG1122	ATPase activity
GPY14_RS00590	COG4721	ABC-type cobalt transport system, permease component
GPY14_RS00595	COG1388	LysM domain
GPY14_RS00595	COG3858	chitin binding
GPY14_RS00610	COG2239	Acts as a magnesium transporter
GPY14_RS00615	COG0789	Transcriptional regulator
GPY14_RS00630	COG1846	Transcriptional regulator
GPY14_RS00635	COG0726	polysaccharide deacetylase
GPY14_RS00640	COG1793	dna ligase
GPY14_RS00640	COG3285	dna ligase
GPY14_RS00645	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GPY14_RS00650	COG0586	Pfam SNARE associated Golgi protein
GPY14_RS00655	COG0861	Integral membrane protein TerC family
GPY14_RS00660	COG1191	sigma factor activity
GPY14_RS00685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY14_RS00690	COG2323	membrane
GPY14_RS00700	COG3594	Acyltransferase
GPY14_RS00705	COG5002	protein histidine kinase activity
GPY14_RS00710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPY14_RS00725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPY14_RS00730	COG0436	Aminotransferase
GPY14_RS00760	COG3852	Histidine kinase
GPY14_RS00765	COG1846	Transcriptional regulator
GPY14_RS00770	COG1360	Flagellar Motor Protein
GPY14_RS00775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPY14_RS00780	COG0542	response to heat
GPY14_RS00785	COG3949	Membrane
GPY14_RS00800	COG0720	synthase
GPY14_RS00805	COG0602	queuosine metabolic process
GPY14_RS00815	COG1733	regulation of RNA biosynthetic process
GPY14_RS00820	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS00830	COG1388	LysM domain
GPY14_RS00830	COG4641	Protein conserved in bacteria
GPY14_RS00835	COG1388	LysM domain
GPY14_RS00840	COG3858	chitin binding
GPY14_RS00850	COG4873	Protein conserved in bacteria
GPY14_RS00860	COG3773	Cell wall hydrolase
GPY14_RS00865	COG2244	polysaccharide biosynthetic process
GPY14_RS00870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY14_RS00875	COG2217	Heavy metal translocating P-type atpase
GPY14_RS00880	COG0006	proline dipeptidase activity
GPY14_RS00885	COG1609	Transcriptional regulator
GPY14_RS00890	COG3711	transcriptional antiterminator
GPY14_RS00895	COG1263	PTS System
GPY14_RS00895	COG2190	(PTS) system
GPY14_RS00895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY14_RS00900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY14_RS00905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPY14_RS00915	COG1533	DNA photolyase activity
GPY14_RS00920	COG0840	transmembrane signaling receptor activity
GPY14_RS00925	COG2084	Dehydrogenase
GPY14_RS00930	COG2340	Cysteine-rich secretory protein family
GPY14_RS00935	COG0768	penicillin binding
GPY14_RS00940	COG4191	Histidine kinase
GPY14_RS00945	COG0436	Aminotransferase
GPY14_RS00950	COG0835	chemotaxis
GPY14_RS00950	COG0784	Response regulator, receiver
GPY14_RS00965	COG2814	Major facilitator Superfamily
GPY14_RS00970	COG1376	ErfK ybiS ycfS ynhG family protein
GPY14_RS00975	COG1408	metallophosphoesterase
GPY14_RS00980	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS00990	COG2200	EAL domain
GPY14_RS00995	COG4703	Protein of unknown function (DUF1797)
GPY14_RS01000	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GPY14_RS01010	COG0517	IMP dehydrogenase activity
GPY14_RS01015	COG0583	DNA-binding transcription factor activity
GPY14_RS01020	COG0716	FMN binding
GPY14_RS01030	COG0716	FMN binding
GPY14_RS01050	COG0668	transmembrane transport
GPY14_RS01055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY14_RS01075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY14_RS01080	COG0303	'Molybdopterin
GPY14_RS01085	COG1763	Mo-molybdopterin cofactor biosynthetic process
GPY14_RS01090	COG0314	molybdopterin synthase activity
GPY14_RS01095	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPY14_RS01105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY14_RS01110	COG1136	(ABC) transporter
GPY14_RS01115	COG0577	efflux transmembrane transporter activity
GPY14_RS01120	COG1349	DNA-binding transcription factor activity
GPY14_RS01125	COG1105	Belongs to the carbohydrate kinase PfkB family
GPY14_RS01130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY14_RS01130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY14_RS01130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY14_RS01135	COG0681	Belongs to the peptidase S26 family
GPY14_RS01145	COG0488	(ABC) transporter
GPY14_RS01150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPY14_RS01155	COG2309	aminopeptidase activity
GPY14_RS01165	COG1077	Cell shape determining protein MreB Mrl
GPY14_RS01170	COG2002	toxin-antitoxin pair type II binding
GPY14_RS01175	COG3852	Histidine kinase
GPY14_RS01180	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GPY14_RS01180	COG2105	PFAM AIG2 family protein
GPY14_RS01185	COG0569	domain protein
GPY14_RS01195	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPY14_RS01205	COG0561	phosphatase activity
GPY14_RS01210	COG0242	peptide deformylase activity
GPY14_RS01220	COG0497	DNA recombination
GPY14_RS01235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY14_RS01235	COG0300	oxidoreductase activity
GPY14_RS01235	COG3321	synthase
GPY14_RS01235	COG4221	oxidoreductase activity
GPY14_RS01240	COG3321	synthase
GPY14_RS01240	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS01240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS01240	COG4221	oxidoreductase activity
GPY14_RS01245	COG0300	oxidoreductase activity
GPY14_RS01245	COG0318	PFAM AMP-dependent synthetase and ligase
GPY14_RS01245	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS01245	COG3321	synthase
GPY14_RS01245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS01250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY14_RS01250	COG4221	oxidoreductase activity
GPY14_RS01250	COG3321	synthase
GPY14_RS01250	COG0300	oxidoreductase activity
GPY14_RS01255	COG3321	synthase
GPY14_RS01255	COG4221	oxidoreductase activity
GPY14_RS01255	COG0300	oxidoreductase activity
GPY14_RS01255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY14_RS01260	COG4221	oxidoreductase activity
GPY14_RS01260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS01260	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS01260	COG3321	synthase
GPY14_RS01265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GPY14_RS01270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GPY14_RS01275	COG0022	dehydrogenase e1 component
GPY14_RS01280	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY14_RS01285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY14_RS01290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY14_RS01305	COG1982	Orn Lys Arg decarboxylase major
GPY14_RS01325	COG0483	inositol monophosphate 1-phosphatase activity
GPY14_RS01335	COG3227	Zinc metalloprotease (Elastase)
GPY14_RS01380	COG4896	Protein conserved in bacteria
GPY14_RS01390	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GPY14_RS01395	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GPY14_RS01400	COG2066	Belongs to the glutaminase family
GPY14_RS01410	COG0772	Belongs to the SEDS family
GPY14_RS01415	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GPY14_RS01430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPY14_RS01430	COG2010	Cytochrome c
GPY14_RS01435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPY14_RS01440	COG1845	cytochrome c oxidase, subunit III
GPY14_RS01445	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GPY14_RS01450	COG3336	cytochrome c oxidase
GPY14_RS01460	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GPY14_RS01465	COG2340	Cysteine-rich secretory protein family
GPY14_RS01480	COG3679	Belongs to the UPF0342 family
GPY14_RS01490	COG0742	ribosomal rna small subunit methyltransferase
GPY14_RS01500	COG3314	Sporulation integral membrane protein YlbJ
GPY14_RS01505	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPY14_RS01510	COG3480	Lon protease (S16) C-terminal proteolytic domain
GPY14_RS01520	COG1399	metal-binding, possibly nucleic acid-binding protein
GPY14_RS01525	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GPY14_RS01540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPY14_RS01560	COG4839	cell division protein FtsL
GPY14_RS01570	COG0768	penicillin binding
GPY14_RS01590	COG0772	Belongs to the SEDS family
GPY14_RS01605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GPY14_RS01615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPY14_RS01620	COG4412	M6 family metalloprotease domain protein
GPY14_RS01620	COG1404	Belongs to the peptidase S8 family
GPY14_RS01635	COG1191	sigma factor activity
GPY14_RS01640	COG1119	ATPase activity
GPY14_RS01645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY14_RS01650	COG1873	PFAM PRC-barrel domain
GPY14_RS01660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPY14_RS01670	COG0762	integral membrane protein
GPY14_RS01675	COG2302	S4 RNA-binding domain
GPY14_RS01680	COG3599	regulation of cell shape
GPY14_RS01685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPY14_RS01690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY14_RS01700	COG0564	pseudouridine synthase activity
GPY14_RS01710	COG2233	PERMEase
GPY14_RS01720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GPY14_RS01725	COG0505	Belongs to the CarA family
GPY14_RS01730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GPY14_RS01745	COG0284	orotidine-5'-phosphate decarboxylase activity
GPY14_RS01750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPY14_RS01760	COG0306	phosphate transporter
GPY14_RS01775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPY14_RS01780	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GPY14_RS01785	COG1648	precorrin-2 dehydrogenase activity
GPY14_RS01800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GPY14_RS01805	COG1561	YicC-like family, N-terminal region
GPY14_RS01810	COG2052	Domain of unknown function (DUF370)
GPY14_RS01815	COG0194	GDP metabolic process
GPY14_RS01825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPY14_RS01830	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPY14_RS01835	COG0242	peptide deformylase activity
GPY14_RS01855	COG0631	protein serine/threonine phosphatase activity
GPY14_RS01860	COG0515	serine threonine protein kinase
GPY14_RS01860	COG2815	serine threonine protein kinase
GPY14_RS01870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPY14_RS01875	COG1564	THIamine pyrophosphokinase
GPY14_RS01890	COG1302	Protein conserved in bacteria
GPY14_RS01895	COG1461	Dihydroxyacetone kinase
GPY14_RS01900	COG1760	l-serine dehydratase
GPY14_RS01905	COG1760	l-serine dehydratase
GPY14_RS01910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPY14_RS01925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GPY14_RS01930	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS01935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY14_RS01945	COG1196	nuclear chromosome segregation
GPY14_RS01950	COG0552	protein localization to endoplasmic reticulum
GPY14_RS01965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPY14_RS01975	COG1837	Belongs to the UPF0109 family
GPY14_RS02000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPY14_RS02015	COG2257	FlhB HrpN YscU SpaS Family
GPY14_RS02025	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GPY14_RS02030	COG0758	DNA mediated transformation
GPY14_RS02035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY14_RS02045	COG4974	Belongs to the 'phage' integrase family
GPY14_RS02065	COG1815	bacterial-type flagellum-dependent cell motility
GPY14_RS02070	COG1558	bacterial-type flagellum-dependent cell motility
GPY14_RS02075	COG1677	Flagellar hook-basal body complex protein FliE
GPY14_RS02080	COG1766	The M ring may be actively involved in energy transduction
GPY14_RS02085	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY14_RS02090	COG1317	bacterial-type flagellum organization
GPY14_RS02095	COG1157	protein secretion by the type III secretion system
GPY14_RS02100	COG2882	bacterial-type flagellum organization
GPY14_RS02105	COG3334	PFAM MgtE intracellular
GPY14_RS02110	COG3144	bacterial-type flagellum assembly
GPY14_RS02115	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPY14_RS02120	COG4786	Flagellar basal body rod
GPY14_RS02125	COG1582	Flagellar protein (FlbD)
GPY14_RS02130	COG1580	Controls the rotational direction of flagella during chemotaxis
GPY14_RS02135	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY14_RS02140	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY14_RS02140	COG1776	CheC inhibitor of MCP methylation
GPY14_RS02145	COG2201	protein-glutamate methylesterase activity
GPY14_RS02150	COG3190	flagellar
GPY14_RS02155	COG1338	Plays a role in the flagellum-specific transport system
GPY14_RS02160	COG1987	bacterial-type flagellum assembly
GPY14_RS02165	COG1684	flagellar biosynthetic protein fliR
GPY14_RS02170	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPY14_RS02175	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPY14_RS02180	COG1419	protein localization to endoplasmic reticulum
GPY14_RS02185	COG0455	bacterial-type flagellum organization
GPY14_RS02190	COG2201	protein-glutamate methylesterase activity
GPY14_RS02195	COG2198	Histidine kinase
GPY14_RS02195	COG0643	Histidine kinase
GPY14_RS02200	COG0835	chemotaxis
GPY14_RS02205	COG1776	CheC inhibitor of MCP methylation
GPY14_RS02215	COG1191	sigma factor activity
GPY14_RS02245	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPY14_RS02250	COG4589	Belongs to the CDS family
GPY14_RS02260	COG0750	zinc metalloprotease
GPY14_RS02270	COG2176	DNA-directed DNA polymerase activity
GPY14_RS02280	COG0195	Participates in both transcription termination and antitermination
GPY14_RS02285	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GPY14_RS02290	COG1358	cellular component organization or biogenesis
GPY14_RS02300	COG1550	Protein conserved in bacteria
GPY14_RS02315	COG0196	riboflavin kinase activity
GPY14_RS02330	COG0726	polysaccharide deacetylase
GPY14_RS02335	COG0612	Peptidase, M16
GPY14_RS02340	COG1873	PFAM PRC-barrel domain
GPY14_RS02345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY14_RS02350	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPY14_RS02355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPY14_RS02360	COG0527	aspartate kinase activity
GPY14_RS02370	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPY14_RS02375	COG0740	serine-type endopeptidase activity
GPY14_RS02385	COG4980	gas vesicle protein
GPY14_RS02385	COG1674	ftsk spoiiie
GPY14_RS02390	COG2188	Transcriptional regulator
GPY14_RS02395	COG2814	Major facilitator Superfamily
GPY14_RS02400	COG1846	Transcriptional regulator
GPY14_RS02405	COG1033	growth of symbiont in host cell
GPY14_RS02405	COG2409	Drug exporters of the RND superfamily
GPY14_RS02410	COG0612	Peptidase, M16
GPY14_RS02415	COG0612	Peptidase, M16
GPY14_RS02420	COG0300	oxidoreductase activity
GPY14_RS02435	COG1426	Protein conserved in bacteria
GPY14_RS02440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPY14_RS02455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GPY14_RS02465	COG1692	metallophosphoesterase
GPY14_RS02470	COG2359	stage V sporulation protein S
GPY14_RS02490	COG4550	Control of competence regulator ComK, YlbF/YmcA
GPY14_RS02510	COG0582	viral genome integration into host DNA
GPY14_RS02550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY14_RS02555	COG3425	synthase
GPY14_RS02560	COG1024	Enoyl-CoA hydratase
GPY14_RS02575	COG3321	synthase
GPY14_RS02575	COG0300	oxidoreductase activity
GPY14_RS02575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY14_RS02575	COG4221	oxidoreductase activity
GPY14_RS02580	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS02580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS02580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY14_RS02580	COG3321	synthase
GPY14_RS02580	COG3321	synthase
GPY14_RS02580	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS02580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS02580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY14_RS02580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY14_RS02580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY14_RS02585	COG4221	oxidoreductase activity
GPY14_RS02585	COG3321	synthase
GPY14_RS02585	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS02585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS02590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY14_RS02590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY14_RS02590	COG3321	synthase
GPY14_RS02590	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GPY14_RS02595	COG2124	cytochrome p450
GPY14_RS02600	COG3209	COG3209 Rhs family protein
GPY14_RS02605	COG3619	membrane
GPY14_RS02615	COG1404	Belongs to the peptidase S8 family
GPY14_RS02625	COG4195	phage-related replication protein
GPY14_RS02630	COG1764	response to oxidative stress
GPY14_RS02640	COG2076	Multidrug Resistance protein
GPY14_RS02680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY14_RS02685	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY14_RS02690	COG4112	unkown
GPY14_RS02695	COG0860	N-Acetylmuramoyl-L-alanine amidase
GPY14_RS02705	COG0464	growth
GPY14_RS02710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPY14_RS02715	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GPY14_RS02720	COG0789	Transcriptional regulator
GPY14_RS02725	COG0174	glutamine synthetase
GPY14_RS02735	COG4282	regulation of fungal-type cell wall biogenesis
GPY14_RS02760	COG2211	Major facilitator Superfamily
GPY14_RS02765	COG3507	Belongs to the glycosyl hydrolase 43 family
GPY14_RS02780	COG1070	Carbohydrate kinase
GPY14_RS02785	COG3848	Pyruvate phosphate dikinase
GPY14_RS02785	COG0574	Belongs to the PEP-utilizing enzyme family
GPY14_RS02805	COG1064	alcohol dehydrogenase
GPY14_RS02825	COG0456	acetyltransferase
GPY14_RS02845	COG3397	chitin binding
GPY14_RS02855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY14_RS02870	COG0756	dUTP diphosphatase activity
GPY14_RS02880	COG4195	phage-related replication protein
GPY14_RS02910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GPY14_RS02920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPY14_RS02940	COG0785	Cytochrome C biogenesis protein
GPY14_RS02945	COG2201	protein-glutamate methylesterase activity
GPY14_RS02950	COG4846	Membrane protein involved in cytochrome C biogenesis
GPY14_RS02960	COG0071	Belongs to the small heat shock protein (HSP20) family
GPY14_RS02975	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GPY14_RS02980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY14_RS03000	COG0824	Thioesterase
GPY14_RS03010	COG4841	protein insertion into membrane
GPY14_RS03020	COG1832	CoA-binding protein
GPY14_RS03025	COG0187	DNA topoisomerase II activity
GPY14_RS03030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPY14_RS03050	COG1063	alcohol dehydrogenase
GPY14_RS03055	COG0800	Aldolase
GPY14_RS03060	COG1312	Catalyzes the dehydration of D-mannonate
GPY14_RS03065	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS03070	COG1609	Transcriptional regulator
GPY14_RS03075	COG2271	Major facilitator Superfamily
GPY14_RS03115	COG0457	Tetratricopeptide repeat
GPY14_RS03145	COG1136	(ABC) transporter
GPY14_RS03145	COG0577	efflux transmembrane transporter activity
GPY14_RS03175	COG2205	protein histidine kinase activity
GPY14_RS03180	COG0745	RESPONSE REGULATOR receiver
GPY14_RS03190	COG3507	Belongs to the glycosyl hydrolase 43 family
GPY14_RS03215	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS03220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GPY14_RS03225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GPY14_RS03230	COG2610	gluconate transmembrane transporter activity
GPY14_RS03235	COG2124	cytochrome p450
GPY14_RS03240	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPY14_RS03255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPY14_RS03265	COG2246	polysaccharide biosynthetic process
GPY14_RS03270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GPY14_RS03275	COG0586	Pfam SNARE associated Golgi protein
GPY14_RS03280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GPY14_RS03285	COG1024	Enoyl-CoA hydratase
GPY14_RS03290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPY14_RS03295	COG0511	ligase activity, forming carbon-carbon bonds
GPY14_RS03300	COG0439	Biotin carboxylase
GPY14_RS03305	COG0318	PFAM AMP-dependent synthetase and ligase
GPY14_RS03310	COG1960	acyl-CoA dehydrogenase activity
GPY14_RS03315	COG1649	PFAM Uncharacterised BCR, COG1649
GPY14_RS03325	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GPY14_RS03325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS03335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS03345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS03350	COG2027	D-alanyl-D-alanine carboxypeptidase
GPY14_RS03355	COG2017	converts alpha-aldose to the beta-anomer
GPY14_RS03360	COG0534	Mate efflux family protein
GPY14_RS03375	COG0582	viral genome integration into host DNA
GPY14_RS03385	COG0405	Gamma-glutamyltransferase
GPY14_RS03390	COG2814	Major facilitator Superfamily
GPY14_RS03395	COG0640	Transcriptional regulator
GPY14_RS03400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPY14_RS03410	COG0604	alcohol dehydrogenase
GPY14_RS03415	COG0493	'glutamate synthase
GPY14_RS03420	COG0070	glutamate synthase
GPY14_RS03420	COG0069	glutamate synthase activity
GPY14_RS03420	COG0067	glutamate synthase
GPY14_RS03425	COG0583	DNA-binding transcription factor activity
GPY14_RS03430	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPY14_RS03445	COG0300	oxidoreductase activity
GPY14_RS03450	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GPY14_RS03460	COG2814	Major facilitator Superfamily
GPY14_RS03465	COG1070	Carbohydrate kinase
GPY14_RS03470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY14_RS03475	COG0243	molybdopterin cofactor binding
GPY14_RS03505	COG5444	nuclease activity
GPY14_RS03510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY14_RS03515	COG2207	Transcriptional regulator
GPY14_RS03515	COG0662	Cupin 2, conserved barrel domain protein
GPY14_RS03520	COG1309	transcriptional regulator
GPY14_RS03525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY14_RS03535	COG0640	Transcriptional regulator
GPY14_RS03540	COG0741	lytic transglycosylase activity
GPY14_RS03545	COG2322	membrane
GPY14_RS03560	COG1619	proteins homologs of microcin C7 resistance protein MccF
GPY14_RS03570	COG1388	LysM domain
GPY14_RS03570	COG3584	3D domain protein
GPY14_RS03575	COG0514	ATP-dependent DNA helicase (RecQ)
GPY14_RS03585	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPY14_RS03590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY14_RS03605	COG0071	Belongs to the small heat shock protein (HSP20) family
GPY14_RS03635	COG1012	belongs to the aldehyde dehydrogenase family
GPY14_RS03645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GPY14_RS03650	COG0733	neurotransmitter:sodium symporter activity
GPY14_RS03655	COG0385	Bile acid
GPY14_RS03660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY14_RS03665	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY14_RS03675	COG4548	von Willebrand factor, type A
GPY14_RS03680	COG0714	Associated with various cellular activities
GPY14_RS03685	COG2032	superoxide dismutase activity
GPY14_RS03690	COG1388	LysM domain
GPY14_RS03690	COG0791	NLP P60 protein
GPY14_RS03695	COG1819	glycosyl
GPY14_RS03700	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPY14_RS03705	COG0534	Mate efflux family protein
GPY14_RS03710	COG1366	Belongs to the anti-sigma-factor antagonist family
GPY14_RS03715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GPY14_RS03720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GPY14_RS03730	COG2962	Rard protein
GPY14_RS03745	COG1942	4-Oxalocrotonate Tautomerase
GPY14_RS03755	COG1733	regulation of RNA biosynthetic process
GPY14_RS03760	COG0778	Nitroreductase
GPY14_RS03765	COG0400	carboxylic ester hydrolase activity
GPY14_RS03770	COG0346	lactoylglutathione lyase activity
GPY14_RS03780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY14_RS03790	COG2723	6-phospho-beta-galactosidase activity
GPY14_RS03795	COG2188	Transcriptional regulator
GPY14_RS03800	COG3409	Peptidoglycan-binding domain 1 protein
GPY14_RS03800	COG0793	Belongs to the peptidase S41A family
GPY14_RS03805	COG2226	methyltransferase
GPY14_RS03815	COG1876	peptidase activity
GPY14_RS03835	COG0671	phosphoesterase, PA-phosphatase related
GPY14_RS03865	COG1509	lysine 2,3-aminomutase activity
GPY14_RS03875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY14_RS03880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GPY14_RS03885	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GPY14_RS03890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPY14_RS03895	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GPY14_RS03905	COG0456	acetyltransferase
GPY14_RS03910	COG0463	Glycosyl transferase, family 2
GPY14_RS03925	COG4641	Protein conserved in bacteria
GPY14_RS03935	COG1086	Polysaccharide biosynthesis protein
GPY14_RS03985	COG1388	LysM domain
GPY14_RS03990	COG0457	Tetratricopeptide repeat
GPY14_RS04015	COG4282	regulation of fungal-type cell wall biogenesis
GPY14_RS04020	COG1525	nuclease
GPY14_RS04045	COG1846	Transcriptional regulator
GPY14_RS04050	COG4698	Protein conserved in bacteria
GPY14_RS04055	COG2755	lipolytic protein G-D-S-L family
GPY14_RS04060	COG1999	signal sequence binding
GPY14_RS04070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GPY14_RS04075	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GPY14_RS04080	COG1272	protein, Hemolysin III
GPY14_RS04085	COG0204	Acyl-transferase
GPY14_RS04090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPY14_RS04105	COG2521	methyltransferase
GPY14_RS04105	COG2136	Putative SAM-dependent methyltransferase
GPY14_RS04120	COG1413	lyase activity
GPY14_RS04130	COG0386	Belongs to the glutathione peroxidase family
GPY14_RS04140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPY14_RS04150	COG1278	Cold shock
GPY14_RS04170	COG0328	RNA-DNA hybrid ribonuclease activity
GPY14_RS04175	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPY14_RS04180	COG0328	RNA-DNA hybrid ribonuclease activity
GPY14_RS04190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY14_RS04215	COG1755	Isoprenylcysteine carboxyl methyltransferase
GPY14_RS04220	COG3424	synthase
GPY14_RS04245	COG1335	isochorismatase
GPY14_RS04255	COG2233	PERMEase
GPY14_RS04265	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPY14_RS04270	COG1199	ATP-dependent helicase activity
GPY14_RS04285	COG0116	Belongs to the methyltransferase superfamily
GPY14_RS04315	COG3359	exonuclease
GPY14_RS04320	COG1205	dead DEAH box helicase
GPY14_RS04320	COG1111	helicase
GPY14_RS04325	COG2190	(PTS) system
GPY14_RS04330	COG0071	Belongs to the small heat shock protein (HSP20) family
GPY14_RS04370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY14_RS04370	COG4499	WXG100 protein secretion system (Wss), protein YukC
GPY14_RS04380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPY14_RS04385	COG3935	DnaD domain protein
GPY14_RS04395	COG0436	Aminotransferase
GPY14_RS04400	COG5353	protein conserved in bacteria
GPY14_RS04410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY14_RS04410	COG1199	ATP-dependent helicase activity
GPY14_RS04440	COG0438	transferase activity, transferring glycosyl groups
GPY14_RS04445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GPY14_RS04460	COG1694	Mazg nucleotide pyrophosphohydrolase
GPY14_RS04465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY14_RS04470	COG2140	Oxalate decarboxylase
GPY14_RS04480	COG4347	Protein of unknown function (DUF1405)
GPY14_RS04485	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPY14_RS04485	COG2010	Cytochrome c
GPY14_RS04490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPY14_RS04495	COG0723	plastoquinol--plastocyanin reductase activity
GPY14_RS04510	COG0457	Tetratricopeptide repeat
GPY14_RS04520	COG0287	Prephenate dehydrogenase
GPY14_RS04555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY14_RS04560	COG4401	Chorismate mutase type I
GPY14_RS04575	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY14_RS04580	COG0105	UTP biosynthetic process
GPY14_RS04585	COG0142	geranyltranstransferase activity
GPY14_RS04595	COG0142	geranyltranstransferase activity
GPY14_RS04610	COG0776	regulation of translation
GPY14_RS04615	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GPY14_RS04655	COG0539	negative regulation of cytoplasmic translation
GPY14_RS04670	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GPY14_RS04675	COG2959	enzyme of heme biosynthesis
GPY14_RS04680	COG3773	Cell wall hydrolase
GPY14_RS04680	COG3409	Peptidoglycan-binding domain 1 protein
GPY14_RS04685	COG2339	peptidase activity
GPY14_RS04690	COG0492	ferredoxin-NADP+ reductase activity
GPY14_RS04695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GPY14_RS04700	COG4862	establishment of competence for transformation
GPY14_RS04705	COG1408	metallophosphoesterase
GPY14_RS04715	COG1388	LysM domain
GPY14_RS04720	COG1266	CAAX protease self-immunity
GPY14_RS04725	COG0514	ATP-dependent DNA helicase (RecQ)
GPY14_RS04730	COG4955	Helix-turn-helix domain
GPY14_RS04735	COG1141	Ferredoxin
GPY14_RS04740	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GPY14_RS04745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY14_RS04755	COG1595	DNA-templated transcription, initiation
GPY14_RS04760	COG5002	protein histidine kinase activity
GPY14_RS04765	COG0745	RESPONSE REGULATOR receiver
GPY14_RS04770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY14_RS04775	COG1333	cytochrome c biogenesis protein
GPY14_RS04780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY14_RS04785	COG1187	pseudouridine synthase activity
GPY14_RS04790	COG0700	Nucleoside recognition
GPY14_RS04795	COG2715	membrane protein required for spore maturation
GPY14_RS04825	COG1547	Domain of unknown function (DUF309)
GPY14_RS04830	COG0456	acetyltransferase
GPY14_RS04845	COG0307	riboflavin synthase, alpha
GPY14_RS04850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY14_RS04850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY14_RS04860	COG0681	Belongs to the peptidase S26 family
GPY14_RS04870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPY14_RS04875	COG4086	secreted protein
GPY14_RS04880	COG0019	diaminopimelate decarboxylase activity
GPY14_RS04885	COG0697	spore germination
GPY14_RS04900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY14_RS04920	COG1191	sigma factor activity
GPY14_RS04930	COG1366	Belongs to the anti-sigma-factor antagonist family
GPY14_RS04935	COG1686	Belongs to the peptidase S11 family
GPY14_RS04945	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPY14_RS04950	COG4974	Belongs to the 'phage' integrase family
GPY14_RS04960	COG0735	belongs to the Fur family
GPY14_RS04965	COG1300	Membrane
GPY14_RS04980	COG0281	malic enzyme
GPY14_RS04985	COG1757	Na H antiporter
GPY14_RS04990	COG1027	Aspartate ammonia-lyase
GPY14_RS04995	COG0252	asparaginase activity
GPY14_RS05000	COG1396	sequence-specific DNA binding
GPY14_RS05005	COG1379	DNA repair
GPY14_RS05010	COG0494	nUDIX hydrolase
GPY14_RS05020	COG0667	Aldo Keto reductase
GPY14_RS05030	COG1073	alpha beta
GPY14_RS05040	COG4918	Iron-sulphur cluster biosynthesis
GPY14_RS05045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPY14_RS05045	COG0456	acetyltransferase
GPY14_RS05050	COG2329	Antibiotic biosynthesis monooxygenase
GPY14_RS05055	COG0456	acetyltransferase
GPY14_RS05060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPY14_RS05075	COG0628	permease
GPY14_RS05085	COG0346	lactoylglutathione lyase activity
GPY14_RS05095	COG3048	D-serine ammonia-lyase activity
GPY14_RS05100	COG0300	oxidoreductase activity
GPY14_RS05110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPY14_RS05115	COG1024	Enoyl-CoA hydratase
GPY14_RS05120	COG3425	synthase
GPY14_RS05125	COG2124	cytochrome p450
GPY14_RS05130	COG3321	synthase
GPY14_RS05130	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS05130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY14_RS05130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS05130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY14_RS05135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY14_RS05135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY14_RS05135	COG3321	synthase
GPY14_RS05135	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS05135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS05140	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS05140	COG3321	synthase
GPY14_RS05140	COG0318	PFAM AMP-dependent synthetase and ligase
GPY14_RS05140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS05140	COG0300	oxidoreductase activity
GPY14_RS05150	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS05150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY14_RS05150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY14_RS05150	COG3321	synthase
GPY14_RS05150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS05155	COG0318	PFAM AMP-dependent synthetase and ligase
GPY14_RS05155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS05155	COG3321	synthase
GPY14_RS05155	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS05155	COG0300	oxidoreductase activity
GPY14_RS05165	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS05170	COG0318	PFAM AMP-dependent synthetase and ligase
GPY14_RS05185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GPY14_RS05185	COG2070	2-Nitropropane dioxygenase
GPY14_RS05190	COG0250	Participates in transcription elongation, termination and antitermination
GPY14_RS05210	COG0596	Alpha beta hydrolase
GPY14_RS05225	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPY14_RS05230	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPY14_RS05245	COG0706	membrane insertase activity
GPY14_RS05250	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY14_RS05255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GPY14_RS05260	COG0346	lactoylglutathione lyase activity
GPY14_RS05270	COG1376	ErfK ybiS ycfS ynhG family protein
GPY14_RS05275	COG4129	membrane
GPY14_RS05280	COG1126	abc transporter atp-binding protein
GPY14_RS05285	COG0765	amino acid transport
GPY14_RS05290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY14_RS05300	COG1597	lipid kinase activity
GPY14_RS05305	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY14_RS05310	COG0022	dehydrogenase e1 component
GPY14_RS05315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GPY14_RS05320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY14_RS05325	COG3426	butyrate kinase activity
GPY14_RS05330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GPY14_RS05335	COG0280	phosphate acetyltransferase
GPY14_RS05340	COG3290	protein histidine kinase activity
GPY14_RS05340	COG3829	transcription factor binding
GPY14_RS05350	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPY14_RS05355	COG2079	MmgE PrpD family protein
GPY14_RS05360	COG0372	Belongs to the citrate synthase family
GPY14_RS05365	COG1960	acyl-CoA dehydrogenase activity
GPY14_RS05370	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPY14_RS05375	COG0183	Belongs to the thiolase family
GPY14_RS05380	COG0584	glycerophosphoryl diester phosphodiesterase
GPY14_RS05385	COG0860	N-Acetylmuramoyl-L-alanine amidase
GPY14_RS05405	COG1902	pentaerythritol trinitrate reductase activity
GPY14_RS05420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY14_RS05425	COG0745	RESPONSE REGULATOR receiver
GPY14_RS05430	COG0750	zinc metalloprotease
GPY14_RS05435	COG0497	DNA recombination
GPY14_RS05445	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GPY14_RS05455	COG0142	geranyltranstransferase activity
GPY14_RS05465	COG1570	exodeoxyribonuclease VII activity
GPY14_RS05480	COG1302	Protein conserved in bacteria
GPY14_RS05490	COG0511	ligase activity, forming carbon-carbon bonds
GPY14_RS05530	COG3854	ATPases associated with a variety of cellular activities
GPY14_RS05545	COG0006	proline dipeptidase activity
GPY14_RS05555	COG3872	metal-dependent enzyme
GPY14_RS05565	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPY14_RS05580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY14_RS05600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GPY14_RS05615	COG1396	sequence-specific DNA binding
GPY14_RS05625	COG0681	Belongs to the peptidase S26 family
GPY14_RS05650	COG4940	Competence protein ComGF
GPY14_RS05660	COG4970	Tfp pilus assembly protein FimT
GPY14_RS05665	COG4537	Required for transformation and DNA binding
GPY14_RS05670	COG1459	type II secretion system
GPY14_RS05675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY14_RS05685	COG1253	flavin adenine dinucleotide binding
GPY14_RS05690	COG1366	Belongs to the anti-sigma-factor antagonist family
GPY14_RS05700	COG1393	Belongs to the ArsC family
GPY14_RS05710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY14_RS05720	COG0011	TIGRFAM Protein of
GPY14_RS05730	COG2866	Carboxypeptidase
GPY14_RS05735	COG1940	carbohydrate kinase activity
GPY14_RS05740	COG4483	Protein conserved in bacteria
GPY14_RS05745	COG1757	Na H antiporter
GPY14_RS05755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPY14_RS05760	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GPY14_RS05770	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPY14_RS05775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY14_RS05780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY14_RS05785	COG0581	inorganic phosphate transmembrane transporter activity
GPY14_RS05790	COG0573	inorganic phosphate transmembrane transporter activity
GPY14_RS05795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY14_RS05805	COG0477	Major facilitator Superfamily
GPY14_RS05810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GPY14_RS05815	COG2839	Protein conserved in bacteria
GPY14_RS05820	COG5521	maltodextrose utilization protein MalA
GPY14_RS05825	COG1388	LysM domain
GPY14_RS05835	COG4709	membrane
GPY14_RS05840	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GPY14_RS05845	COG0735	belongs to the Fur family
GPY14_RS05850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY14_RS05865	COG0513	Belongs to the DEAD box helicase family
GPY14_RS05880	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPY14_RS05885	COG2384	SAM-dependent methyltransferase
GPY14_RS05890	COG2010	Cytochrome c
GPY14_RS05895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPY14_RS05900	COG0358	DNA primase activity
GPY14_RS05915	COG0517	IMP dehydrogenase activity
GPY14_RS05920	COG0751	glycine-tRNA ligase activity
GPY14_RS05940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPY14_RS05945	COG0295	cytidine deaminase activity
GPY14_RS05950	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY14_RS05960	COG1480	7TM receptor with intracellular HD hydrolase
GPY14_RS05965	COG1702	phosphate starvation-inducible protein PhoH
GPY14_RS05970	COG0561	phosphatase activity
GPY14_RS05985	COG4864	UPF0365 protein
GPY14_RS05990	COG1030	water channel activity
GPY14_RS05995	COG1610	YqeY-like protein
GPY14_RS06000	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GPY14_RS06005	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPY14_RS06010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPY14_RS06045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY14_RS06060	COG0860	N-Acetylmuramoyl-L-alanine amidase
GPY14_RS06075	COG1466	dna polymerase III delta subunit
GPY14_RS06090	COG0658	competence protein
GPY14_RS06090	COG2333	competence protein COMEC
GPY14_RS06095	COG2131	deaminase
GPY14_RS06100	COG1555	photosystem II stabilization
GPY14_RS06100	COG1596	polysaccharide export
GPY14_RS06105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPY14_RS06110	COG2226	methyltransferase
GPY14_RS06115	COG0799	negative regulation of ribosome biogenesis
GPY14_RS06120	COG1713	HD superfamily hydrolase involved in NAD metabolism
GPY14_RS06130	COG1534	Rna-binding protein
GPY14_RS06135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPY14_RS06140	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPY14_RS06145	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GPY14_RS06155	COG2755	lipolytic protein G-D-S-L family
GPY14_RS06160	COG0726	polysaccharide deacetylase
GPY14_RS06165	COG0398	Pfam SNARE associated Golgi protein
GPY14_RS06190	COG1794	racemase activity, acting on amino acids and derivatives
GPY14_RS06200	COG0656	L-ascorbic acid biosynthetic process
GPY14_RS06230	COG5002	protein histidine kinase activity
GPY14_RS06230	COG0642	Histidine kinase
GPY14_RS06235	COG0745	RESPONSE REGULATOR receiver
GPY14_RS06240	COG2311	Membrane
GPY14_RS06250	COG0454	-acetyltransferase
GPY14_RS06255	COG0563	adenylate kinase activity
GPY14_RS06265	COG2814	Major facilitator Superfamily
GPY14_RS06275	COG0456	acetyltransferase
GPY14_RS06280	COG2318	DinB family
GPY14_RS06295	COG0561	phosphatase activity
GPY14_RS06305	COG1482	cell wall glycoprotein biosynthetic process
GPY14_RS06310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY14_RS06310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY14_RS06310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY14_RS06315	COG3711	transcriptional antiterminator
GPY14_RS06315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY14_RS06325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPY14_RS06330	COG0583	DNA-binding transcription factor activity
GPY14_RS06335	COG2814	Major facilitator Superfamily
GPY14_RS06340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY14_RS06340	COG2124	cytochrome p450
GPY14_RS06345	COG1309	transcriptional regulator
GPY14_RS06350	COG2226	methyltransferase
GPY14_RS06360	COG2116	formate transmembrane transporter activity
GPY14_RS06365	COG5609	conserved protein (DUF2294)
GPY14_RS06370	COG3383	formate dehydrogenase (NAD+) activity
GPY14_RS06375	COG2427	Protein of unknown function (DUF1641)
GPY14_RS06385	COG0626	cystathionine gamma-synthase activity
GPY14_RS06390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPY14_RS06450	COG5632	N-Acetylmuramoyl-L-alanine amidase
GPY14_RS06450	COG3409	Peptidoglycan-binding domain 1 protein
GPY14_RS06455	COG4824	toxin secretion phage lysis holin
GPY14_RS06475	COG5434	Belongs to the glycosyl hydrolase 28 family
GPY14_RS06480	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPY14_RS06490	COG5280	Phage tail tape measure protein TP901
GPY14_RS06490	COG3953	SLT domain
GPY14_RS06580	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GPY14_RS06675	COG1396	sequence-specific DNA binding
GPY14_RS06710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPY14_RS06725	COG4472	Bacterial protein of unknown function (DUF965)
GPY14_RS06735	COG0628	permease
GPY14_RS06740	COG1126	abc transporter atp-binding protein
GPY14_RS06745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY14_RS06750	COG0765	amino acid transport
GPY14_RS06755	COG0765	amino acid transport
GPY14_RS06770	COG3881	PFAM PRC-barrel domain
GPY14_RS06775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GPY14_RS06780	COG0457	Tetratricopeptide repeat
GPY14_RS06790	COG1104	cysteine desulfurase activity
GPY14_RS06795	COG1959	2 iron, 2 sulfur cluster binding
GPY14_RS06800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GPY14_RS06805	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GPY14_RS06840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY14_RS06850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GPY14_RS06850	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GPY14_RS06855	COG5416	Lipopolysaccharide assembly protein A domain
GPY14_RS06860	COG0490	domain, Protein
GPY14_RS06865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY14_RS06865	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY14_RS06880	COG2323	membrane
GPY14_RS06890	COG1862	Preprotein translocase
GPY14_RS06935	COG1388	LysM domain
GPY14_RS06945	COG0157	Belongs to the NadC ModD family
GPY14_RS06950	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GPY14_RS06955	COG1104	cysteine desulfurase activity
GPY14_RS06960	COG1827	regulation of RNA biosynthetic process
GPY14_RS06965	COG0077	Prephenate dehydratase
GPY14_RS06980	COG3290	protein histidine kinase activity
GPY14_RS06985	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GPY14_RS06990	COG2868	ribosomal protein
GPY14_RS07000	COG1994	Peptidase M50
GPY14_RS07005	COG0739	heme binding
GPY14_RS07010	COG2894	cell division
GPY14_RS07020	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GPY14_RS07025	COG1792	Involved in formation and maintenance of cell shape
GPY14_RS07030	COG1077	Cell shape determining protein MreB Mrl
GPY14_RS07050	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GPY14_RS07055	COG0285	dihydrofolate synthase activity
GPY14_RS07060	COG0525	valine-tRNA ligase activity
GPY14_RS07070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPY14_RS07085	COG0113	porphobilinogen synthase activity
GPY14_RS07090	COG1587	Uroporphyrinogen-III synthase
GPY14_RS07100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY14_RS07120	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPY14_RS07125	COG0470	DNA polymerase III
GPY14_RS07125	COG1067	ATP-dependent peptidase activity
GPY14_RS07140	COG0457	Tetratricopeptide repeat
GPY14_RS07140	COG1477	protein flavinylation
GPY14_RS07155	COG0473	3-isopropylmalate dehydrogenase activity
GPY14_RS07170	COG0440	acetolactate synthase activity
GPY14_RS07175	COG0028	Belongs to the TPP enzyme family
GPY14_RS07195	COG0732	type I restriction modification DNA specificity domain
GPY14_RS07205	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GPY14_RS07225	COG0622	Phosphoesterase
GPY14_RS07230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPY14_RS07240	COG5401	PFAM Sporulation and spore germination
GPY14_RS07250	COG1846	Transcriptional regulator
GPY14_RS07255	COG2197	response regulator
GPY14_RS07260	COG0824	Thioesterase
GPY14_RS07265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPY14_RS07270	COG1053	succinate dehydrogenase
GPY14_RS07275	COG2009	succinate dehydrogenase
GPY14_RS07280	COG1719	4-vinyl reductase, 4VR
GPY14_RS07295	COG3118	belongs to the thioredoxin family
GPY14_RS07300	COG3534	alpha-L-arabinofuranosidase
GPY14_RS07305	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GPY14_RS07310	COG2086	electron transfer activity
GPY14_RS07315	COG1024	Enoyl-CoA hydratase
GPY14_RS07320	COG1309	transcriptional regulator
GPY14_RS07325	COG0318	PFAM AMP-dependent synthetase and ligase
GPY14_RS07335	COG3766	membrane
GPY14_RS07345	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPY14_RS07345	COG1796	DNA polymerase
GPY14_RS07350	COG1286	toxin biosynthetic process
GPY14_RS07365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY14_RS07365	COG0072	phenylalanine-tRNA ligase activity
GPY14_RS07370	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPY14_RS07375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY14_RS07385	COG3835	regulator
GPY14_RS07390	COG0277	FAD linked oxidase domain protein
GPY14_RS07395	COG0247	lactate metabolic process
GPY14_RS07400	COG1966	Carbon starvation protein
GPY14_RS07405	COG3534	alpha-L-arabinofuranosidase
GPY14_RS07410	COG0395	ABC-type sugar transport system, permease component
GPY14_RS07415	COG1175	transmembrane transport
GPY14_RS07420	COG1653	transport
GPY14_RS07430	COG0647	UMP catabolic process
GPY14_RS07435	COG0235	Class ii aldolase
GPY14_RS07440	COG1069	ribulokinase activity
GPY14_RS07445	COG2160	L-arabinose isomerase activity
GPY14_RS07450	COG3507	Belongs to the glycosyl hydrolase 43 family
GPY14_RS07455	COG1363	Peptidase, m42
GPY14_RS07465	COG3326	Membrane
GPY14_RS07470	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPY14_RS07480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GPY14_RS07485	COG1346	cytolysis
GPY14_RS07490	COG1380	Effector of murein hydrolase LrgA
GPY14_RS07495	COG3279	Response regulator of the LytR AlgR family
GPY14_RS07500	COG3275	phosphorelay sensor kinase activity
GPY14_RS07520	COG0398	Pfam SNARE associated Golgi protein
GPY14_RS07525	COG1484	DNA-dependent DNA replication
GPY14_RS07545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY14_RS07550	COG1733	regulation of RNA biosynthetic process
GPY14_RS07555	COG2814	Major facilitator Superfamily
GPY14_RS07560	COG0656	L-ascorbic acid biosynthetic process
GPY14_RS07565	COG0237	dephospho-CoA kinase activity
GPY14_RS07570	COG1971	Probably functions as a manganese efflux pump
GPY14_RS07575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GPY14_RS07580	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY14_RS07580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY14_RS07585	COG5002	protein histidine kinase activity
GPY14_RS07590	COG0745	RESPONSE REGULATOR receiver
GPY14_RS07600	COG0538	isocitrate dehydrogenase activity
GPY14_RS07605	COG0372	Belongs to the citrate synthase family
GPY14_RS07625	COG0628	permease
GPY14_RS07630	COG3030	protein affecting phage T7 exclusion by the F plasmid
GPY14_RS07635	COG0469	pyruvate kinase activity
GPY14_RS07655	COG0281	malic enzyme
GPY14_RS07660	COG0587	DNA-directed DNA polymerase activity
GPY14_RS07680	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GPY14_RS07690	COG4109	DRTGG domain
GPY14_RS07700	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS07715	COG0521	Mo-molybdopterin cofactor biosynthetic process
GPY14_RS07725	COG0827	DNA restriction-modification system
GPY14_RS07730	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GPY14_RS07735	COG3874	Sporulation protein YtfJ
GPY14_RS07745	COG1714	RDD family
GPY14_RS07750	COG0616	signal peptide processing
GPY14_RS07755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPY14_RS07760	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GPY14_RS07785	COG1114	Component of the transport system for branched-chain amino acids
GPY14_RS07795	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPY14_RS07800	COG1309	transcriptional regulator
GPY14_RS07805	COG1956	GAF domain-containing protein
GPY14_RS07810	COG2199	diguanylate cyclase activity
GPY14_RS07810	COG2203	Gaf domain
GPY14_RS07825	COG1012	belongs to the aldehyde dehydrogenase family
GPY14_RS07830	COG4282	regulation of fungal-type cell wall biogenesis
GPY14_RS07835	COG1017	nitric oxide dioxygenase activity
GPY14_RS07835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY14_RS07845	COG0693	protein deglycase activity
GPY14_RS07860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPY14_RS07865	COG1378	Sugar-specific transcriptional regulator TrmB
GPY14_RS07885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY14_RS07890	COG0454	-acetyltransferase
GPY14_RS07895	COG0517	IMP dehydrogenase activity
GPY14_RS07900	COG0123	including yeast histone deacetylase and acetoin utilization protein
GPY14_RS07905	COG1360	Flagellar Motor Protein
GPY14_RS07910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPY14_RS07915	COG1609	Transcriptional regulator
GPY14_RS07920	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GPY14_RS07920	COG1605	Chorismate mutase
GPY14_RS07925	COG3118	belongs to the thioredoxin family
GPY14_RS07930	COG4980	gas vesicle protein
GPY14_RS07935	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GPY14_RS07950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY14_RS07960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY14_RS07970	COG1363	Peptidase, m42
GPY14_RS07975	COG5584	Small secreted protein
GPY14_RS07980	COG0281	malic enzyme
GPY14_RS07985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY14_RS08000	COG0510	thiamine kinase activity
GPY14_RS08005	COG1597	lipid kinase activity
GPY14_RS08015	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GPY14_RS08020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPY14_RS08025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY14_RS08030	COG2252	PERMEase
GPY14_RS08035	COG4473	ABC transporter
GPY14_RS08040	COG1131	(ABC) transporter
GPY14_RS08045	COG1349	DNA-binding transcription factor activity
GPY14_RS08050	COG1187	pseudouridine synthase activity
GPY14_RS08055	COG2244	polysaccharide biosynthetic process
GPY14_RS08060	COG2081	HI0933 family
GPY14_RS08065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY14_RS08095	COG1486	melibiose metabolic process
GPY14_RS08105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY14_RS08120	COG1366	Belongs to the anti-sigma-factor antagonist family
GPY14_RS08120	COG2202	Pas domain
GPY14_RS08125	COG2814	Major facilitator Superfamily
GPY14_RS08130	COG5522	Integral membrane protein (intg_mem_TP0381)
GPY14_RS08135	COG0577	efflux transmembrane transporter activity
GPY14_RS08140	COG1136	(ABC) transporter
GPY14_RS08145	COG2205	protein histidine kinase activity
GPY14_RS08150	COG0745	RESPONSE REGULATOR receiver
GPY14_RS08155	COG0577	efflux transmembrane transporter activity
GPY14_RS08160	COG1136	(ABC) transporter
GPY14_RS08180	COG1131	(ABC) transporter
GPY14_RS08185	COG1725	Transcriptional regulator
GPY14_RS08195	COG1242	4 iron, 4 sulfur cluster binding
GPY14_RS08200	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GPY14_RS08210	COG0584	glycerophosphoryl diester phosphodiesterase
GPY14_RS08220	COG2267	carboxylic ester hydrolase activity
GPY14_RS08225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPY14_RS08230	COG1113	amino acid transport
GPY14_RS08235	COG0367	asparagine synthase
GPY14_RS08255	COG1506	peptidase
GPY14_RS08260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GPY14_RS08265	COG1116	anion transmembrane transporter activity
GPY14_RS08270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPY14_RS08275	COG0494	nUDIX hydrolase
GPY14_RS08280	COG4824	toxin secretion phage lysis holin
GPY14_RS08285	COG0783	Belongs to the Dps family
GPY14_RS08310	COG0288	reversible hydration of carbon dioxide
GPY14_RS08320	COG1271	oxidase subunit
GPY14_RS08325	COG1294	oxidase, subunit
GPY14_RS08335	COG4948	Mandelate Racemase Muconate Lactonizing
GPY14_RS08345	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPY14_RS08350	COG0596	Alpha beta hydrolase
GPY14_RS08360	COG1169	isochorismate synthase
GPY14_RS08365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY14_RS08370	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GPY14_RS08495	COG3859	Proton-coupled thiamine transporter YuaJ
GPY14_RS08500	COG2268	Band 7 protein
GPY14_RS08505	COG1585	Membrane protein implicated in regulation of membrane protease activity
GPY14_RS08510	COG2318	DinB family
GPY14_RS08520	COG1454	alcohol dehydrogenase
GPY14_RS08530	COG1510	regulation of RNA biosynthetic process
GPY14_RS08540	COG0569	domain protein
GPY14_RS08545	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPY14_RS08550	COG1017	nitric oxide dioxygenase activity
GPY14_RS08550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY14_RS08575	COG0628	permease
GPY14_RS08580	COG0673	inositol 2-dehydrogenase activity
GPY14_RS08585	COG0693	protein deglycase activity
GPY14_RS08590	COG0840	transmembrane signaling receptor activity
GPY14_RS08595	COG0840	transmembrane signaling receptor activity
GPY14_RS08600	COG0840	transmembrane signaling receptor activity
GPY14_RS08605	COG0840	transmembrane signaling receptor activity
GPY14_RS08620	COG2070	2-Nitropropane dioxygenase
GPY14_RS08625	COG0432	Pfam Uncharacterised protein family UPF0047
GPY14_RS08630	COG0366	Alpha amylase catalytic
GPY14_RS08635	COG1253	flavin adenine dinucleotide binding
GPY14_RS08640	COG2738	Putative neutral zinc metallopeptidase
GPY14_RS08655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPY14_RS08680	COG1335	isochorismatase
GPY14_RS08685	COG1979	alcohol dehydrogenase
GPY14_RS08690	COG1979	alcohol dehydrogenase
GPY14_RS08695	COG2155	Conserved Protein
GPY14_RS08700	COG1098	S1 RNA binding domain
GPY14_RS08705	COG0436	Aminotransferase
GPY14_RS08710	COG1522	sequence-specific DNA binding
GPY14_RS08715	COG2267	carboxylic ester hydrolase activity
GPY14_RS08725	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GPY14_RS08730	COG2205	protein histidine kinase activity
GPY14_RS08740	COG5018	Exonuclease
GPY14_RS08745	COG2814	Major facilitator Superfamily
GPY14_RS08750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY14_RS08755	COG3011	Protein conserved in bacteria
GPY14_RS08770	COG4565	transcriptional regulatory protein
GPY14_RS08800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GPY14_RS08800	COG2111	Na H antiporter
GPY14_RS08805	COG2111	Na H antiporter
GPY14_RS08810	COG1006	Multisubunit Na H antiporter MnhC subunit
GPY14_RS08815	COG0651	ATP synthesis coupled electron transport
GPY14_RS08820	COG1863	multisubunit Na H antiporter MnhE subunit
GPY14_RS08825	COG2212	antiporter activity
GPY14_RS08830	COG1320	monovalent cation:proton antiporter activity
GPY14_RS08835	COG2050	protein possibly involved in aromatic compounds catabolism
GPY14_RS08840	COG2197	response regulator
GPY14_RS08845	COG4585	Histidine kinase
GPY14_RS08855	COG0142	geranyltranstransferase activity
GPY14_RS08870	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY14_RS08875	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPY14_RS08880	COG1335	isochorismatase
GPY14_RS08885	COG5506	Protein of unknown function (DUF1694)
GPY14_RS08900	COG0628	permease
GPY14_RS08910	COG1418	mRNA catabolic process
GPY14_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS08925	COG1511	domain protein
GPY14_RS08930	COG0433	COG0433 Predicted ATPase
GPY14_RS08930	COG1674	ftsk spoiiie
GPY14_RS08935	COG4499	WXG100 protein secretion system (Wss), protein YukC
GPY14_RS08940	COG5417	Belongs to the EsaB family
GPY14_RS08945	COG4842	Belongs to the WXG100 family
GPY14_RS08950	COG2508	Transcriptional regulator
GPY14_RS08950	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GPY14_RS08955	COG0686	Belongs to the AlaDH PNT family
GPY14_RS08960	COG5634	Uncharacterized conserved protein (DUF2278)
GPY14_RS08965	COG3251	PFAM MbtH domain protein
GPY14_RS08970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS08980	COG1021	2,3-dihydroxybenzoate-AMP ligase
GPY14_RS08985	COG1169	isochorismate synthase
GPY14_RS08990	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS08995	COG2819	hydrolase of the alpha beta superfamily
GPY14_RS09000	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GPY14_RS09005	COG1268	BioY protein
GPY14_RS09010	COG2056	Na+-H+ antiporter family
GPY14_RS09020	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GPY14_RS09025	COG3584	3D domain protein
GPY14_RS09040	COG1252	NADH dehydrogenase
GPY14_RS09065	COG1131	(ABC) transporter
GPY14_RS09085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY14_RS09090	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GPY14_RS09105	COG0316	Belongs to the HesB IscA family
GPY14_RS09115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY14_RS09125	COG1252	NADH dehydrogenase
GPY14_RS09130	COG4837	Protein of unknown function (DUF1462)
GPY14_RS09135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GPY14_RS09140	COG1506	peptidase
GPY14_RS09140	COG0823	Involved in the tonB-independent uptake of proteins
GPY14_RS09140	COG4946	Tricorn protease homolog
GPY14_RS09150	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPY14_RS09155	COG0460	homoserine dehydrogenase
GPY14_RS09160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPY14_RS09165	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPY14_RS09175	COG2445	Protein of unknown function DUF86
GPY14_RS09180	COG4470	Protein conserved in bacteria
GPY14_RS09190	COG0739	heme binding
GPY14_RS09200	COG0737	Belongs to the 5'-nucleotidase family
GPY14_RS09205	COG0730	response to heat
GPY14_RS09210	COG1801	Protein of unknown function DUF72
GPY14_RS09225	COG2508	Transcriptional regulator
GPY14_RS09240	COG2814	Major facilitator Superfamily
GPY14_RS09245	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPY14_RS09250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY14_RS09255	COG2356	endonuclease I
GPY14_RS09260	COG3842	ATPase activity
GPY14_RS09265	COG2188	Transcriptional regulator
GPY14_RS09270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY14_RS09275	COG0395	ABC-type sugar transport system, permease component
GPY14_RS09280	COG1175	transmembrane transport
GPY14_RS09285	COG1653	transport
GPY14_RS09290	COG2222	sugar isomerase
GPY14_RS09295	COG0789	Transcriptional regulator
GPY14_RS09320	COG0322	excinuclease ABC activity
GPY14_RS09325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY14_RS09330	COG2226	methyltransferase
GPY14_RS09340	COG3409	Peptidoglycan-binding domain 1 protein
GPY14_RS09350	COG0719	Fe-S assembly protein
GPY14_RS09355	COG0822	iron-sulfur transferase activity
GPY14_RS09360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPY14_RS09365	COG0719	Fe-S assembly protein
GPY14_RS09370	COG0396	ATPase activity
GPY14_RS09380	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPY14_RS09385	COG1464	Belongs to the NlpA lipoprotein family
GPY14_RS09390	COG2011	ABC-type metal ion transport system permease component
GPY14_RS09395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPY14_RS09405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY14_RS09410	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GPY14_RS09425	COG1393	Belongs to the ArsC family
GPY14_RS09430	COG1960	acyl-CoA dehydrogenase activity
GPY14_RS09435	COG0183	Belongs to the thiolase family
GPY14_RS09440	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPY14_RS09440	COG1024	Enoyl-CoA hydratase
GPY14_RS09455	COG0477	Major facilitator Superfamily
GPY14_RS09465	COG5577	PFAM Coat F domain
GPY14_RS09470	COG1846	Transcriptional regulator
GPY14_RS09475	COG0477	Major facilitator Superfamily
GPY14_RS09480	COG0583	DNA-binding transcription factor activity
GPY14_RS09500	COG1120	ATPase activity
GPY14_RS09515	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS09520	COG0783	Belongs to the Dps family
GPY14_RS09525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY14_RS09530	COG0745	RESPONSE REGULATOR receiver
GPY14_RS09535	COG2770	Histidine kinase
GPY14_RS09535	COG2205	protein histidine kinase activity
GPY14_RS09545	COG1309	transcriptional regulator
GPY14_RS09550	COG0114	fumarate hydratase activity
GPY14_RS09560	COG0697	spore germination
GPY14_RS09565	COG0814	amino acid
GPY14_RS09575	COG2197	response regulator
GPY14_RS09580	COG4585	Histidine kinase
GPY14_RS09585	COG4758	membrane
GPY14_RS09590	COG3595	metallopeptidase activity
GPY14_RS09595	COG1842	Phage shock protein A
GPY14_RS09600	COG4758	membrane
GPY14_RS09605	COG2814	Major facilitator Superfamily
GPY14_RS09610	COG2096	Adenosyltransferase
GPY14_RS09615	COG1120	ATPase activity
GPY14_RS09620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY14_RS09625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY14_RS09630	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS09635	COG3386	PFAM SMP-30 Gluconolaconase
GPY14_RS09640	COG2205	protein histidine kinase activity
GPY14_RS09645	COG0745	RESPONSE REGULATOR receiver
GPY14_RS09655	COG1191	sigma factor activity
GPY14_RS09665	COG2140	Oxalate decarboxylase
GPY14_RS09675	COG1120	ATPase activity
GPY14_RS09680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY14_RS09685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY14_RS09690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY14_RS09695	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GPY14_RS09700	COG0531	amino acid
GPY14_RS09710	COG1988	membrane-bound metal-dependent
GPY14_RS09715	COG1368	sulfuric ester hydrolase activity
GPY14_RS09720	COG1910	domain protein
GPY14_RS09725	COG0725	ABC transporter, periplasmic molybdate-binding protein
GPY14_RS09730	COG4149	molybdate abc transporter
GPY14_RS09735	COG2197	response regulator
GPY14_RS09740	COG3850	Histidine kinase
GPY14_RS09745	COG1131	(ABC) transporter
GPY14_RS09755	COG0842	Transport permease protein
GPY14_RS09760	COG0656	L-ascorbic acid biosynthetic process
GPY14_RS09780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY14_RS09785	COG3973	AAA domain
GPY14_RS09790	COG2860	membrane
GPY14_RS09800	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GPY14_RS09805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY14_RS09810	COG2217	Heavy metal translocating P-type atpase
GPY14_RS09815	COG2217	Heavy metal translocating P-type atpase
GPY14_RS09820	COG2608	mercury ion transmembrane transporter activity
GPY14_RS09825	COG1937	Protein conserved in bacteria
GPY14_RS09830	COG0673	inositol 2-dehydrogenase activity
GPY14_RS09845	COG2814	Major facilitator Superfamily
GPY14_RS09865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY14_RS09870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPY14_RS09875	COG1126	abc transporter atp-binding protein
GPY14_RS09880	COG0765	amino acid transport
GPY14_RS09885	COG0765	amino acid transport
GPY14_RS09890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY14_RS09895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY14_RS09905	COG0583	DNA-binding transcription factor activity
GPY14_RS09910	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS09915	COG2732	(Barnase) inhibitor
GPY14_RS09920	COG2732	(Barnase) inhibitor
GPY14_RS09935	COG0557	exoribonuclease II activity
GPY14_RS09940	COG1647	Serine aminopeptidase, S33
GPY14_RS09945	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY14_RS09950	COG1476	TRANSCRIPTIONal
GPY14_RS09955	COG1396	sequence-specific DNA binding
GPY14_RS09960	COG1396	sequence-specific DNA binding
GPY14_RS09965	COG1733	regulation of RNA biosynthetic process
GPY14_RS09995	COG1174	glycine betaine transport
GPY14_RS10000	COG1732	Glycine betaine
GPY14_RS10005	COG1174	glycine betaine transport
GPY14_RS10010	COG0517	IMP dehydrogenase activity
GPY14_RS10010	COG1125	glycine betaine transport
GPY14_RS10015	COG1510	regulation of RNA biosynthetic process
GPY14_RS10020	COG1174	glycine betaine transport
GPY14_RS10025	COG1732	Glycine betaine
GPY14_RS10030	COG1174	glycine betaine transport
GPY14_RS10035	COG1125	glycine betaine transport
GPY14_RS10035	COG0517	IMP dehydrogenase activity
GPY14_RS10040	COG1510	regulation of RNA biosynthetic process
GPY14_RS10045	COG2095	MarC family integral membrane protein
GPY14_RS10050	COG3064	Membrane
GPY14_RS10055	COG4640	response to antibiotic
GPY14_RS10060	COG0456	acetyltransferase
GPY14_RS10075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GPY14_RS10095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY14_RS10100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPY14_RS10110	COG2234	aminopeptidase activity
GPY14_RS10130	COG0126	phosphoglycerate kinase activity
GPY14_RS10135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY14_RS10140	COG2390	Transcriptional regulator
GPY14_RS10145	COG2814	Major facilitator Superfamily
GPY14_RS10150	COG1609	Transcriptional regulator
GPY14_RS10155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPY14_RS10165	COG0583	DNA-binding transcription factor activity
GPY14_RS10170	COG0697	spore germination
GPY14_RS10185	COG1609	Transcriptional regulator
GPY14_RS10195	COG0561	phosphatase activity
GPY14_RS10200	COG1737	Transcriptional regulator
GPY14_RS10205	COG1070	Carbohydrate kinase
GPY14_RS10230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY14_RS10235	COG2186	Transcriptional regulator
GPY14_RS10240	COG1620	l-lactate permease
GPY14_RS10245	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GPY14_RS10255	COG5039	Polysaccharide pyruvyl transferase
GPY14_RS10260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPY14_RS10265	COG0110	maltose O-acetyltransferase activity
GPY14_RS10270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPY14_RS10275	COG2244	polysaccharide biosynthetic process
GPY14_RS10280	COG1216	Glycosyl transferase, family 2
GPY14_RS10285	COG5039	Polysaccharide pyruvyl transferase
GPY14_RS10290	COG1216	Glycosyl transferase, family 2
GPY14_RS10300	COG0438	transferase activity, transferring glycosyl groups
GPY14_RS10305	COG1215	transferase activity, transferring glycosyl groups
GPY14_RS10310	COG0438	transferase activity, transferring glycosyl groups
GPY14_RS10315	COG1086	Polysaccharide biosynthesis protein
GPY14_RS10320	COG0489	protein tyrosine kinase activity
GPY14_RS10325	COG3944	biosynthesis protein
GPY14_RS10330	COG1396	sequence-specific DNA binding
GPY14_RS10335	COG2272	Belongs to the type-B carboxylesterase lipase family
GPY14_RS10340	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPY14_RS10345	COG2364	Membrane
GPY14_RS10350	COG0456	acetyltransferase
GPY14_RS10355	COG3479	Phenolic acid decarboxylase
GPY14_RS10415	COG2211	Major facilitator Superfamily
GPY14_RS10420	COG1609	Transcriptional regulator
GPY14_RS10440	COG2814	Major facilitator Superfamily
GPY14_RS10440	COG0477	Major facilitator Superfamily
GPY14_RS10445	COG1611	Belongs to the LOG family
GPY14_RS10450	COG1694	Mazg nucleotide pyrophosphohydrolase
GPY14_RS10455	COG0659	secondary active sulfate transmembrane transporter activity
GPY14_RS10460	COG0288	reversible hydration of carbon dioxide
GPY14_RS10465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY14_RS10470	COG4290	ribonuclease
GPY14_RS10475	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GPY14_RS10480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY14_RS10490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GPY14_RS10500	COG1051	belongs to the nudix hydrolase family
GPY14_RS10505	COG0492	ferredoxin-NADP+ reductase activity
GPY14_RS10515	COG0457	Tetratricopeptide repeat
GPY14_RS10520	COG5002	protein histidine kinase activity
GPY14_RS10525	COG0745	RESPONSE REGULATOR receiver
GPY14_RS10535	COG1132	(ABC) transporter
GPY14_RS10540	COG0140	phosphoribosyl-ATP diphosphatase activity
GPY14_RS10540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPY14_RS10565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPY14_RS10580	COG4990	cell redox homeostasis
GPY14_RS10585	COG0110	maltose O-acetyltransferase activity
GPY14_RS10605	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPY14_RS10620	COG1309	transcriptional regulator
GPY14_RS10625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GPY14_RS10630	COG1950	PFAM Membrane protein of
GPY14_RS10635	COG1983	PspC domain protein
GPY14_RS10640	COG3595	metallopeptidase activity
GPY14_RS10655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPY14_RS10665	COG4897	Protein conserved in bacteria
GPY14_RS10670	COG0574	Belongs to the PEP-utilizing enzyme family
GPY14_RS10670	COG3848	Pyruvate phosphate dikinase
GPY14_RS10675	COG1309	transcriptional regulator
GPY14_RS10680	COG2814	Major facilitator Superfamily
GPY14_RS10710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS10740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY14_RS10750	COG3409	Peptidoglycan-binding domain 1 protein
GPY14_RS10750	COG0793	Belongs to the peptidase S41A family
GPY14_RS10755	COG3420	alginic acid biosynthetic process
GPY14_RS10760	COG2177	Part of the ABC transporter FtsEX involved in
GPY14_RS10765	COG2884	Cell division ATP-binding protein ftsE
GPY14_RS10770	COG2010	Cytochrome c
GPY14_RS10775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY14_RS10790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY14_RS10805	COG1516	flagellar protein fliS
GPY14_RS10810	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPY14_RS10815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY14_RS10835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY14_RS10845	COG3418	PFAM FlgN family protein
GPY14_RS10850	COG2747	anti-sigma28 factor FlgM
GPY14_RS10860	COG1040	competence protein
GPY14_RS10870	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GPY14_RS10875	COG1307	EDD domain protein, DegV family
GPY14_RS10880	COG2197	response regulator
GPY14_RS10885	COG4585	Histidine kinase
GPY14_RS10890	COG1739	Uncharacterized protein family UPF0029
GPY14_RS10895	COG1316	TRANSCRIPTIONal
GPY14_RS10900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPY14_RS10905	COG0438	transferase activity, transferring glycosyl groups
GPY14_RS10910	COG1215	transferase activity, transferring glycosyl groups
GPY14_RS10915	COG3206	protein involved in exopolysaccharide biosynthesis
GPY14_RS10920	COG3307	-O-antigen
GPY14_RS10925	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GPY14_RS10930	COG0297	glycogen (starch) synthase activity
GPY14_RS10930	COG0438	transferase activity, transferring glycosyl groups
GPY14_RS10935	COG2244	polysaccharide biosynthetic process
GPY14_RS10945	COG2247	cell wall binding repeat
GPY14_RS10945	COG0860	N-Acetylmuramoyl-L-alanine amidase
GPY14_RS10950	COG2385	sporulation resulting in formation of a cellular spore
GPY14_RS10950	COG2247	cell wall binding repeat
GPY14_RS10960	COG1316	TRANSCRIPTIONal
GPY14_RS10965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GPY14_RS10970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GPY14_RS10975	COG1134	teichoic acid transport
GPY14_RS10980	COG1682	transport, permease protein
GPY14_RS10985	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GPY14_RS10995	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GPY14_RS11000	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GPY14_RS11005	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GPY14_RS11010	COG4193	domain, Protein
GPY14_RS11015	COG1482	cell wall glycoprotein biosynthetic process
GPY14_RS11020	COG0697	spore germination
GPY14_RS11025	COG0814	amino acid
GPY14_RS11035	COG1215	transferase activity, transferring glycosyl groups
GPY14_RS11040	COG2814	Major facilitator Superfamily
GPY14_RS11045	COG1316	TRANSCRIPTIONal
GPY14_RS11050	COG0561	phosphatase activity
GPY14_RS11055	COG2433	Pfam Transposase IS66
GPY14_RS11060	COG0791	NLP P60 protein
GPY14_RS11070	COG2843	Capsule synthesis protein
GPY14_RS11080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPY14_RS11085	COG0697	spore germination
GPY14_RS11090	COG0814	amino acid
GPY14_RS11100	COG1609	Transcriptional regulator
GPY14_RS11105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY14_RS11115	COG1129	ABC transporter
GPY14_RS11120	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPY14_RS11125	COG1879	ABC-type sugar transport system periplasmic component
GPY14_RS11130	COG3103	Sh3 type 3 domain protein
GPY14_RS11135	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY14_RS11145	COG0028	Belongs to the TPP enzyme family
GPY14_RS11150	COG0583	DNA-binding transcription factor activity
GPY14_RS11155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPY14_RS11170	COG5337	Spore coat protein CotH
GPY14_RS11180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GPY14_RS11190	COG0405	Gamma-glutamyltransferase
GPY14_RS11195	COG1522	sequence-specific DNA binding
GPY14_RS11200	COG2059	Chromate
GPY14_RS11205	COG2059	Chromate
GPY14_RS11260	COG5444	nuclease activity
GPY14_RS11275	COG3878	Protein conserved in bacteria
GPY14_RS11280	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GPY14_RS11285	COG4464	protein tyrosine phosphatase activity
GPY14_RS11290	COG0489	protein tyrosine kinase activity
GPY14_RS11295	COG3944	biosynthesis protein
GPY14_RS11305	COG4715	Zinc finger, swim domain protein
GPY14_RS11310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GPY14_RS11315	COG0561	phosphatase activity
GPY14_RS11320	COG1349	DNA-binding transcription factor activity
GPY14_RS11325	COG0629	single-stranded DNA binding
GPY14_RS11350	COG0457	Tetratricopeptide repeat
GPY14_RS11355	COG4786	Flagellar basal body rod
GPY14_RS11360	COG4786	Flagellar basal body rod
GPY14_RS11365	COG1077	Cell shape determining protein MreB Mrl
GPY14_RS11370	COG1609	Transcriptional regulator
GPY14_RS11375	COG1846	Transcriptional regulator
GPY14_RS11380	COG2814	Major facilitator Superfamily
GPY14_RS11385	COG1953	Uracil, thiamine, allantoin
GPY14_RS11390	COG0477	Major facilitator Superfamily
GPY14_RS11395	COG1335	isochorismatase
GPY14_RS11400	COG0004	ammonium transporteR
GPY14_RS11405	COG0347	Belongs to the P(II) protein family
GPY14_RS11410	COG0772	Belongs to the SEDS family
GPY14_RS11415	COG0671	phosphoesterase, PA-phosphatase related
GPY14_RS11425	COG0739	heme binding
GPY14_RS11430	COG1247	-acetyltransferase
GPY14_RS11445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY14_RS11460	COG0726	polysaccharide deacetylase
GPY14_RS11465	COG1959	2 iron, 2 sulfur cluster binding
GPY14_RS11480	COG0831	urea catabolic process
GPY14_RS11490	COG1994	Peptidase M50
GPY14_RS11495	COG0457	Tetratricopeptide repeat
GPY14_RS11505	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPY14_RS11510	COG2304	oxidoreductase activity
GPY14_RS11515	COG2304	oxidoreductase activity
GPY14_RS11520	COG2385	sporulation resulting in formation of a cellular spore
GPY14_RS11525	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPY14_RS11535	COG4836	Membrane
GPY14_RS11575	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPY14_RS11605	COG0698	ribose 5-phosphate isomerase
GPY14_RS11610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPY14_RS11620	COG0009	L-threonylcarbamoyladenylate synthase
GPY14_RS11625	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPY14_RS11645	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY14_RS11650	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPY14_RS11655	COG0346	lactoylglutathione lyase activity
GPY14_RS11660	COG0789	Transcriptional regulator
GPY14_RS11665	COG0679	Auxin Efflux Carrier
GPY14_RS11670	COG0281	malic enzyme
GPY14_RS11680	COG0254	rRNA binding
GPY14_RS11685	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPY14_RS11695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPY14_RS11705	COG0191	fructose-bisphosphate aldolase activity
GPY14_RS11710	COG2204	response regulator
GPY14_RS11715	COG4821	SIS domain
GPY14_RS11730	COG2181	nitrate reductase activity
GPY14_RS11730	COG0247	lactate metabolic process
GPY14_RS11735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY14_RS11750	COG1132	(ABC) transporter
GPY14_RS11755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY14_RS11765	COG2181	nitrate reductase activity
GPY14_RS11770	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GPY14_RS11775	COG1140	nitrate reductase beta subunit
GPY14_RS11780	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GPY14_RS11785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY14_RS11795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY14_RS11800	COG2223	nitrite transmembrane transporter activity
GPY14_RS11810	COG4506	Protein conserved in bacteria
GPY14_RS11825	COG3391	amine dehydrogenase activity
GPY14_RS11830	COG0457	Tetratricopeptide repeat
GPY14_RS11875	COG0010	Belongs to the arginase family
GPY14_RS11880	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GPY14_RS11885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY14_RS11900	COG1994	Peptidase M50
GPY14_RS11905	COG1942	4-Oxalocrotonate Tautomerase
GPY14_RS11910	COG1846	Transcriptional regulator
GPY14_RS11915	COG0531	amino acid
GPY14_RS11920	COG3465	dGTPase activity
GPY14_RS11925	COG1078	dGTPase activity
GPY14_RS11940	COG1695	Transcriptional regulator
GPY14_RS11950	COG1131	(ABC) transporter
GPY14_RS11955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GPY14_RS11985	COG0583	DNA-binding transcription factor activity
GPY14_RS11990	COG2855	membrane
GPY14_RS11995	COG0280	phosphate acetyltransferase
GPY14_RS12005	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS12010	COG0436	Aminotransferase
GPY14_RS12040	COG2814	Major facilitator Superfamily
GPY14_RS12045	COG2814	Major facilitator Superfamily
GPY14_RS12050	COG0833	amino acid
GPY14_RS12055	COG4187	Peptidase family M20/M25/M40
GPY14_RS12060	COG1012	belongs to the aldehyde dehydrogenase family
GPY14_RS12065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GPY14_RS12075	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GPY14_RS12080	COG1091	dTDP-4-dehydrorhamnose reductase activity
GPY14_RS12085	COG1088	dTDP-glucose 4,6-dehydratase activity
GPY14_RS12090	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPY14_RS12095	COG3980	spore coat polysaccharide biosynthesis protein
GPY14_RS12100	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GPY14_RS12105	COG2089	acid synthase
GPY14_RS12110	COG0456	acetyltransferase
GPY14_RS12115	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPY14_RS12120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GPY14_RS12125	COG0463	Glycosyl transferase, family 2
GPY14_RS12135	COG2363	Small membrane protein
GPY14_RS12140	COG2233	PERMEase
GPY14_RS12155	COG1216	Glycosyl transferase, family 2
GPY14_RS12165	COG0351	phosphomethylpyrimidine kinase
GPY14_RS12175	COG1621	beta-fructofuranosidase activity
GPY14_RS12180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY14_RS12180	COG1263	PTS System
GPY14_RS12185	COG3711	transcriptional antiterminator
GPY14_RS12195	COG1404	Belongs to the peptidase S8 family
GPY14_RS12200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPY14_RS12205	COG0778	Nitroreductase
GPY14_RS12210	COG0772	Belongs to the SEDS family
GPY14_RS12215	COG0454	-acetyltransferase
GPY14_RS12235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPY14_RS12240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPY14_RS12245	COG2261	transglycosylase associated protein
GPY14_RS12250	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GPY14_RS12255	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPY14_RS12260	COG2246	polysaccharide biosynthetic process
GPY14_RS12265	COG1309	transcriptional regulator
GPY14_RS12285	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GPY14_RS12290	COG2837	iron assimilation
GPY14_RS12295	COG2822	iron ion transport
GPY14_RS12310	COG0583	DNA-binding transcription factor activity
GPY14_RS12320	COG1346	cytolysis
GPY14_RS12325	COG4895	conserved protein (DUF2196)
GPY14_RS12330	COG0789	Transcriptional regulator
GPY14_RS12335	COG5504	Zn-dependent protease
GPY14_RS12340	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY14_RS12345	COG0346	lactoylglutathione lyase activity
GPY14_RS12350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY14_RS12355	COG1404	Belongs to the peptidase S8 family
GPY14_RS12360	COG1442	glycosyl transferase family 8
GPY14_RS12365	COG2357	RelA SpoT domain protein
GPY14_RS12370	COG1575	Belongs to the MenA family. Type 1 subfamily
GPY14_RS12385	COG1696	Membrane protein involved in D-alanine export
GPY14_RS12395	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GPY14_RS12400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPY14_RS12405	COG1486	melibiose metabolic process
GPY14_RS12410	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPY14_RS12415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY14_RS12420	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY14_RS12425	COG3711	transcriptional antiterminator
GPY14_RS12425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY14_RS12435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY14_RS12450	COG0640	Transcriptional regulator
GPY14_RS12455	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPY14_RS12460	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY14_RS12465	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPY14_RS12470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY14_RS12475	COG2723	6-phospho-beta-galactosidase activity
GPY14_RS12480	COG1940	carbohydrate kinase activity
GPY14_RS12485	COG1482	cell wall glycoprotein biosynthetic process
GPY14_RS12495	COG0753	catalase activity
GPY14_RS12500	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GPY14_RS12505	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GPY14_RS12510	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GPY14_RS12515	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPY14_RS12520	COG4988	ABC transporter
GPY14_RS12525	COG1294	oxidase, subunit
GPY14_RS12530	COG1271	oxidase subunit
GPY14_RS12535	COG3493	citrate carrier protein
GPY14_RS12540	COG0726	polysaccharide deacetylase
GPY14_RS12545	COG3842	ATPase activity
GPY14_RS12550	COG2508	Transcriptional regulator
GPY14_RS12555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY14_RS12565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY14_RS12575	COG4894	glucomannan catabolic process
GPY14_RS12580	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPY14_RS12585	COG0500	methyltransferase
GPY14_RS12590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY14_RS12610	COG2851	Citrate transporter
GPY14_RS12615	COG2273	Hydrolase Family 16
GPY14_RS12625	COG2270	Major facilitator Superfamily
GPY14_RS12630	COG0513	Belongs to the DEAD box helicase family
GPY14_RS12680	COG3209	COG3209 Rhs family protein
GPY14_RS12690	COG0697	spore germination
GPY14_RS12695	COG0589	response to stress
GPY14_RS12700	COG2723	6-phospho-beta-galactosidase activity
GPY14_RS12715	COG3507	Belongs to the glycosyl hydrolase 43 family
GPY14_RS12740	COG0010	Belongs to the arginase family
GPY14_RS12745	COG0833	amino acid
GPY14_RS12750	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GPY14_RS12755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY14_RS12765	COG2390	Transcriptional regulator
GPY14_RS12770	COG0561	phosphatase activity
GPY14_RS12800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY14_RS12805	COG5294	Protein conserved in bacteria
GPY14_RS12810	COG0577	efflux transmembrane transporter activity
GPY14_RS12815	COG1136	(ABC) transporter
GPY14_RS12820	COG2205	protein histidine kinase activity
GPY14_RS12825	COG0745	RESPONSE REGULATOR receiver
GPY14_RS12830	COG2205	protein histidine kinase activity
GPY14_RS12835	COG0745	RESPONSE REGULATOR receiver
GPY14_RS12865	COG1082	Xylose isomerase domain protein TIM barrel
GPY14_RS12875	COG2814	Major facilitator Superfamily
GPY14_RS12905	COG1349	DNA-binding transcription factor activity
GPY14_RS12910	COG0667	Aldo Keto reductase
GPY14_RS12915	COG2814	Major facilitator Superfamily
GPY14_RS12930	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS12935	COG2197	response regulator
GPY14_RS12940	COG4585	Histidine kinase
GPY14_RS12945	COG3239	Fatty acid desaturase
GPY14_RS12950	COG1309	transcriptional regulator
GPY14_RS12955	COG1012	belongs to the aldehyde dehydrogenase family
GPY14_RS12960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY14_RS12970	COG0640	Transcriptional regulator
GPY14_RS12975	COG2814	Major facilitator Superfamily
GPY14_RS12980	COG1714	RDD family
GPY14_RS12990	COG0450	alkyl hydroperoxide reductase
GPY14_RS12995	COG3634	alkyl hydroperoxide reductase activity
GPY14_RS13000	COG3177	Filamentation induced by cAMP protein fic
GPY14_RS13005	COG1113	amino acid transport
GPY14_RS13015	COG2080	2 iron, 2 sulfur cluster binding
GPY14_RS13030	COG2068	MobA-Related Protein
GPY14_RS13035	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GPY14_RS13075	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GPY14_RS13080	COG0667	Aldo Keto reductase
GPY14_RS13085	COG0456	acetyltransferase
GPY14_RS13090	COG0457	Tetratricopeptide repeat
GPY14_RS13095	COG0010	Belongs to the arginase family
GPY14_RS13100	COG0833	amino acid
GPY14_RS13105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPY14_RS13110	COG5658	integral membrane protein
GPY14_RS13115	COG0640	Transcriptional regulator
GPY14_RS13120	COG3829	transcription factor binding
GPY14_RS13130	COG0488	(ABC) transporter
GPY14_RS13145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY14_RS13150	COG5002	protein histidine kinase activity
GPY14_RS13150	COG3850	Histidine kinase
GPY14_RS13160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY14_RS13165	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GPY14_RS13170	COG4853	Protein conserved in bacteria
GPY14_RS13175	COG4863	YycH protein
GPY14_RS13180	COG5002	protein histidine kinase activity
GPY14_RS13185	COG0745	RESPONSE REGULATOR receiver
GPY14_RS13215	COG0346	lactoylglutathione lyase activity
GPY14_RS13220	COG0305	Participates in initiation and elongation during chromosome replication
GPY14_RS13240	COG3093	addiction module antidote protein HigA
GPY14_RS13245	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GPY14_RS13260	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPY14_RS13265	COG0438	transferase activity, transferring glycosyl groups
GPY14_RS13285	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GPY14_RS13290	COG4241	membrane
GPY14_RS13300	COG5577	PFAM Coat F domain
GPY14_RS13305	COG1733	regulation of RNA biosynthetic process
GPY14_RS13315	COG0697	spore germination
GPY14_RS13325	COG1621	beta-fructofuranosidase activity
GPY14_RS13330	COG1802	Transcriptional regulator
GPY14_RS13335	COG2318	DinB family
GPY14_RS13340	COG2211	Major facilitator Superfamily
GPY14_RS13345	COG0583	DNA-binding transcription factor activity
GPY14_RS13360	COG0778	Nitroreductase
GPY14_RS13365	COG1846	Transcriptional regulator
GPY14_RS13375	COG1846	Transcriptional regulator
GPY14_RS13380	COG2153	protein acetylation
GPY14_RS13390	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPY14_RS13395	COG0583	DNA-binding transcription factor activity
GPY14_RS13400	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS13405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY14_RS13410	COG0697	spore germination
GPY14_RS13415	COG1331	Highly conserved protein containing a thioredoxin domain
GPY14_RS13420	COG1266	CAAX protease self-immunity
GPY14_RS13425	COG2814	Major facilitator Superfamily
GPY14_RS13425	COG0477	Major facilitator Superfamily
GPY14_RS13430	COG0346	lactoylglutathione lyase activity
GPY14_RS13435	COG1609	Transcriptional regulator
GPY14_RS13440	COG0708	Exodeoxyribonuclease III
GPY14_RS13445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPY14_RS13450	COG2169	Transcriptional regulator
GPY14_RS13460	COG0629	single-stranded DNA binding
GPY14_RS13470	COG0012	GTP binding
GPY14_RS13475	COG0243	molybdopterin cofactor binding
GPY14_RS13480	COG4481	Protein conserved in bacteria
GPY14_RS13485	COG3949	Membrane
GPY14_RS13500	COG1475	DNA binding
GPY14_RS13505	COG1192	Involved in chromosome partitioning
GPY14_RS13530	COG1847	R3H domain protein
GPY14_RS13535	COG0706	membrane insertase activity
GPY14_RS13545	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GPY14_RS13555	COG0592	DNA-directed DNA polymerase activity
GPY14_RS13560	COG2501	S4 domain
GPY14_RS13580	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPY14_RS13615	COG0516	GMP reductase activity
GPY14_RS13615	COG0517	IMP dehydrogenase activity
GPY14_RS13620	COG1686	Belongs to the peptidase S11 family
GPY14_RS13640	COG1929	Belongs to the glycerate kinase type-1 family
GPY14_RS13650	COG1428	Deoxynucleoside kinase
GPY14_RS13655	COG1428	Deoxynucleoside kinase
GPY14_RS13660	COG1388	LysM domain
GPY14_RS13660	COG3858	chitin binding
GPY14_RS13665	COG1335	isochorismatase
GPY14_RS13670	COG0590	tRNA wobble adenosine to inosine editing
GPY14_RS13680	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPY14_RS13685	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPY14_RS13690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPY14_RS13735	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GPY14_RS13740	COG3853	Toxic anion resistance protein (TelA)
GPY14_RS13745	COG1982	Orn Lys Arg decarboxylase major
GPY14_RS13755	COG3870	Protein conserved in bacteria
GPY14_RS13760	COG1728	Protein conserved in bacteria
GPY14_RS13765	COG0470	DNA polymerase III
GPY14_RS13770	COG1774	PSP1 C-terminal conserved region
GPY14_RS13780	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GPY14_RS13790	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPY14_RS13795	COG2002	toxin-antitoxin pair type II binding
GPY14_RS13805	COG0084	hydrolase, TatD family'
GPY14_RS13810	COG3584	3D domain protein
GPY14_RS13810	COG3583	domain protein
GPY14_RS13815	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GPY14_RS13820	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GPY14_RS13830	COG4466	Protein conserved in bacteria
GPY14_RS13845	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPY14_RS13850	COG0251	oxidation-reduction process
GPY14_RS13865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPY14_RS13885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPY14_RS13890	COG2002	toxin-antitoxin pair type II binding
GPY14_RS13895	COG2244	polysaccharide biosynthetic process
GPY14_RS13900	COG3956	TIGRFAM MazG family protein
GPY14_RS13905	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPY14_RS13920	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GPY14_RS13925	COG1098	S1 RNA binding domain
GPY14_RS13940	COG2208	phosphoserine phosphatase activity
GPY14_RS13945	COG2304	oxidoreductase activity
GPY14_RS13950	COG0515	serine threonine protein kinase
GPY14_RS13955	COG0037	tRNA processing
GPY14_RS13965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPY14_RS13980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY14_RS13985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPY14_RS13990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY14_RS13995	COG0512	Glutamine amidotransferase of anthranilate synthase
GPY14_RS14000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPY14_RS14005	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPY14_RS14010	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPY14_RS14015	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY14_RS14020	COG1396	sequence-specific DNA binding
GPY14_RS14025	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY14_RS14030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GPY14_RS14110	COG4463	regulation of RNA biosynthetic process
GPY14_RS14115	COG3880	PFAM UvrB UvrC protein
GPY14_RS14125	COG0542	response to heat
GPY14_RS14130	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPY14_RS14135	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GPY14_RS14140	COG4956	integral membrane protein (PIN domain superfamily)
GPY14_RS14160	COG1045	serine acetyltransferase
GPY14_RS14170	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GPY14_RS14175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY14_RS14180	COG3688	RNA-binding protein containing a PIN domain
GPY14_RS14185	COG1595	DNA-templated transcription, initiation
GPY14_RS14190	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GPY14_RS14195	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY14_RS14200	COG0250	Participates in transcription elongation, termination and antitermination
GPY14_RS14205	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPY14_RS14220	COG0222	ribosome binding
GPY14_RS14225	COG2813	Specifically methylates the guanine in position
GPY14_RS14240	COG1358	cellular component organization or biogenesis
GPY14_RS14265	COG0596	Alpha beta hydrolase
GPY14_RS14270	COG0051	transcription antitermination factor activity, RNA binding
GPY14_RS14285	COG0089	rRNA binding
GPY14_RS14295	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPY14_RS14300	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPY14_RS14310	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPY14_RS14315	COG0255	Belongs to the universal ribosomal protein uL29 family
GPY14_RS14365	COG1841	ribosomal large subunit assembly
GPY14_RS14385	COG0024	Methionine aminopeptidase
GPY14_RS14395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPY14_RS14400	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GPY14_RS14425	COG1122	ATPase activity
GPY14_RS14430	COG1122	ATPase activity
GPY14_RS14435	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPY14_RS14455	COG2226	methyltransferase
GPY14_RS14460	COG2318	DinB family
GPY14_RS14470	COG0860	N-Acetylmuramoyl-L-alanine amidase
GPY14_RS14475	COG0489	protein tyrosine kinase activity
GPY14_RS14485	COG2194	sulfuric ester hydrolase activity
GPY14_RS14490	COG0726	polysaccharide deacetylase
GPY14_RS14555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPY14_RS14570	COG0659	secondary active sulfate transmembrane transporter activity
GPY14_RS14575	COG0385	Bile acid
GPY14_RS14580	COG2819	hydrolase of the alpha beta superfamily
GPY14_RS14585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY14_RS14590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY14_RS14595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY14_RS14600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY14_RS14600	COG2207	Transcriptional regulator
GPY14_RS14605	COG3876	Protein conserved in bacteria
GPY14_RS14610	COG1472	Belongs to the glycosyl hydrolase 3 family
GPY14_RS14615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GPY14_RS14620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY14_RS14620	COG1263	PTS System
GPY14_RS14630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY14_RS14635	COG1683	Conserved Protein
GPY14_RS14665	COG1595	DNA-templated transcription, initiation
GPY14_RS14670	COG5662	AntiSigma factor
GPY14_RS14675	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPY14_RS14680	COG4856	YbbR-like protein
GPY14_RS14720	COG1346	cytolysis
GPY14_RS14725	COG1380	Effector of murein hydrolase LrgA
GPY14_RS14730	COG1846	Transcriptional regulator
GPY14_RS14735	COG1113	amino acid transport
GPY14_RS14740	COG1011	Hydrolase
GPY14_RS14750	COG2197	response regulator
GPY14_RS14755	COG1131	(ABC) transporter
GPY14_RS14805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS14805	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS14805	COG3321	synthase
GPY14_RS14805	COG4221	oxidoreductase activity
GPY14_RS14810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS14810	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS14810	COG3321	synthase
GPY14_RS14810	COG0318	PFAM AMP-dependent synthetase and ligase
GPY14_RS14810	COG0300	oxidoreductase activity
GPY14_RS14850	COG0531	amino acid
GPY14_RS14855	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GPY14_RS14870	COG0584	glycerophosphoryl diester phosphodiesterase
GPY14_RS14875	COG2271	Major facilitator Superfamily
GPY14_RS14885	COG2368	4-hydroxyphenylacetate
GPY14_RS14895	COG3409	Peptidoglycan-binding domain 1 protein
GPY14_RS14910	COG0371	Dehydrogenase
GPY14_RS14920	COG1183	phosphatidylcholine synthase activity
GPY14_RS14925	COG0586	Pfam SNARE associated Golgi protein
GPY14_RS14930	COG0688	phosphatidylethanolamine metabolic process
GPY14_RS14945	COG1301	dicarboxylic acid transport
GPY14_RS14950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPY14_RS14955	COG0833	amino acid
GPY14_RS14960	COG2040	homocysteine
GPY14_RS14965	COG1115	amino acid carrier protein
GPY14_RS14970	COG2066	Belongs to the glutaminase family
GPY14_RS14975	COG4191	Histidine kinase
GPY14_RS14980	COG0784	Response regulator, receiver
GPY14_RS14995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPY14_RS15000	COG0778	Nitroreductase
GPY14_RS15005	COG0346	lactoylglutathione lyase activity
GPY14_RS15010	COG2259	Doxx family
GPY14_RS15015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY14_RS15025	COG3773	Cell wall hydrolase
GPY14_RS15030	COG3540	Alkaline phosphatase
GPY14_RS15035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPY14_RS15040	COG0805	protein transport
GPY14_RS15050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPY14_RS15060	COG1309	transcriptional regulator
GPY14_RS15065	COG0252	asparaginase activity
GPY14_RS15070	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPY14_RS15075	COG3012	SEC-C Motif Domain Protein
GPY14_RS15075	COG1405	negative regulation of cell septum assembly
GPY14_RS15080	COG0667	Aldo Keto reductase
GPY14_RS15090	COG1595	DNA-templated transcription, initiation
GPY14_RS15095	COG1595	DNA-templated transcription, initiation
GPY14_RS15100	COG1876	peptidase activity
GPY14_RS15105	COG0457	Tetratricopeptide repeat
GPY14_RS15120	COG0803	Belongs to the bacterial solute-binding protein 9 family
GPY14_RS15125	COG1121	(ABC) transporter
GPY14_RS15135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPY14_RS15140	COG2310	stress, protein
GPY14_RS15145	COG2310	stress, protein
GPY14_RS15150	COG2310	stress, protein
GPY14_RS15155	COG0861	Integral membrane protein TerC family
GPY14_RS15165	COG3853	Toxic anion resistance protein (TelA)
GPY14_RS15175	COG0517	IMP dehydrogenase activity
GPY14_RS15175	COG4175	Glycine betaine
GPY14_RS15180	COG4176	ABC-type proline glycine betaine transport system permease component
GPY14_RS15185	COG2113	Glycine betaine
GPY14_RS15190	COG1473	amidohydrolase
GPY14_RS15195	COG1288	antiporter activity
GPY14_RS15205	COG0366	Alpha amylase catalytic
GPY14_RS15215	COG2814	Major facilitator Superfamily
GPY14_RS15220	COG1846	Transcriptional regulator
GPY14_RS15225	COG1280	lysine exporter protein (LysE YggA)
GPY14_RS15230	COG3403	YqcI/YcgG family
GPY14_RS15235	COG1113	amino acid transport
GPY14_RS15240	COG3665	Urea carboxylase-associated protein
GPY14_RS15255	COG1660	Displays ATPase and GTPase activities
GPY14_RS15260	COG1082	Xylose isomerase domain protein TIM barrel
GPY14_RS15265	COG2271	Major facilitator Superfamily
GPY14_RS15270	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GPY14_RS15275	COG3458	cephalosporin-C deacetylase activity
GPY14_RS15280	COG3541	Predicted nucleotidyltransferase
GPY14_RS15285	COG0506	proline dehydrogenase activity
GPY14_RS15290	COG1012	belongs to the aldehyde dehydrogenase family
GPY14_RS15295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY14_RS15300	COG2508	Transcriptional regulator
GPY14_RS15310	COG1587	Uroporphyrinogen-III synthase
GPY14_RS15310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPY14_RS15315	COG2146	nitrite reductase [NAD(P)H] activity
GPY14_RS15320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY14_RS15325	COG0243	molybdopterin cofactor binding
GPY14_RS15330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY14_RS15335	COG2223	nitrite transmembrane transporter activity
GPY14_RS15340	COG0523	cobalamin synthesis protein
GPY14_RS15345	COG1063	alcohol dehydrogenase
GPY14_RS15350	COG1714	RDD family
GPY14_RS15360	COG2723	6-phospho-beta-galactosidase activity
GPY14_RS15370	COG3209	COG3209 Rhs family protein
GPY14_RS15375	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GPY14_RS15380	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GPY14_RS15385	COG1733	regulation of RNA biosynthetic process
GPY14_RS15395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS15400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY14_RS15405	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GPY14_RS15420	COG0697	spore germination
GPY14_RS15425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY14_RS15435	COG2364	Membrane
GPY14_RS15440	COG1126	abc transporter atp-binding protein
GPY14_RS15445	COG0765	amino acid transport
GPY14_RS15450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY14_RS15455	COG0583	DNA-binding transcription factor activity
GPY14_RS15460	COG0163	prenyltransferase activity
GPY14_RS15465	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GPY14_RS15480	COG3104	oligopeptide transport
GPY14_RS15495	COG0697	spore germination
GPY14_RS15505	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GPY14_RS15520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY14_RS15525	COG0765	amino acid transport
GPY14_RS15530	COG1126	abc transporter atp-binding protein
GPY14_RS15540	COG2079	MmgE PrpD family protein
GPY14_RS15545	COG1136	(ABC) transporter
GPY14_RS15550	COG0577	efflux transmembrane transporter activity
GPY14_RS15555	COG0745	RESPONSE REGULATOR receiver
GPY14_RS15560	COG3850	Histidine kinase
GPY14_RS15560	COG5002	protein histidine kinase activity
GPY14_RS15565	COG0457	Tetratricopeptide repeat
GPY14_RS15580	COG0527	aspartate kinase activity
GPY14_RS15585	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY14_RS15590	COG4605	iron ion homeostasis
GPY14_RS15595	COG4604	ABC transporter, ATP-binding protein
GPY14_RS15600	COG4607	ABC-type enterochelin transport system periplasmic component
GPY14_RS15605	COG2814	Major facilitator Superfamily
GPY14_RS15610	COG1309	transcriptional regulator
GPY14_RS15615	COG0778	Nitroreductase
GPY14_RS15620	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GPY14_RS15625	COG0640	Transcriptional regulator
GPY14_RS15630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY14_RS15635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPY14_RS15640	COG1012	belongs to the aldehyde dehydrogenase family
GPY14_RS15645	COG4975	Glucose uptake
GPY14_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS15655	COG4549	nuclear export factor GLE1
GPY14_RS15660	COG1276	copper resistance
GPY14_RS15660	COG2372	response to copper ion
GPY14_RS15665	COG1349	DNA-binding transcription factor activity
GPY14_RS15675	COG2213	PTS system mannitol-specific
GPY14_RS15680	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY14_RS15690	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY14_RS15700	COG0561	phosphatase activity
GPY14_RS15710	COG1914	H( )-stimulated, divalent metal cation uptake system
GPY14_RS15720	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GPY14_RS15725	COG1984	allophanate hydrolase subunit 2
GPY14_RS15730	COG1414	Transcriptional regulator
GPY14_RS15735	COG2755	lipolytic protein G-D-S-L family
GPY14_RS15745	COG2329	Antibiotic biosynthesis monooxygenase
GPY14_RS15750	COG0768	penicillin binding
GPY14_RS15755	COG4989	oxidoreductase activity
GPY14_RS15760	COG3711	transcriptional antiterminator
GPY14_RS15765	COG0318	PFAM AMP-dependent synthetase and ligase
GPY14_RS15770	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS15775	COG1917	Cupin 2, conserved barrel domain protein
GPY14_RS15780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY14_RS15785	COG3871	stress protein (general stress protein 26)
GPY14_RS15795	COG2814	Major facilitator Superfamily
GPY14_RS15800	COG1522	sequence-specific DNA binding
GPY14_RS15805	COG0551	DNA topoisomerase type I activity
GPY14_RS15805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY14_RS15810	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GPY14_RS15815	COG3706	GGDEF domain
GPY14_RS15820	COG5298	Protein conserved in bacteria
GPY14_RS15825	COG1215	transferase activity, transferring glycosyl groups
GPY14_RS15835	COG0531	amino acid
GPY14_RS15840	COG0494	nUDIX hydrolase
GPY14_RS15845	COG0028	Belongs to the TPP enzyme family
GPY14_RS15900	COG1914	H( )-stimulated, divalent metal cation uptake system
GPY14_RS15910	COG4876	unkown
GPY14_RS15925	COG2217	Heavy metal translocating P-type atpase
GPY14_RS15930	COG3729	General stress protein
GPY14_RS15935	COG0662	Cupin 2, conserved barrel domain protein
GPY14_RS15940	COG2329	Antibiotic biosynthesis monooxygenase
GPY14_RS15945	COG3546	catalase activity
GPY14_RS15950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPY14_RS15960	COG4565	transcriptional regulatory protein
GPY14_RS15965	COG1301	dicarboxylic acid transport
GPY14_RS15970	COG0628	permease
GPY14_RS15975	COG1131	(ABC) transporter
GPY14_RS15990	COG1960	acyl-CoA dehydrogenase activity
GPY14_RS16005	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPY14_RS16010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY14_RS16020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPY14_RS16030	COG0513	Belongs to the DEAD box helicase family
GPY14_RS16035	COG3402	PFAM membrane-flanked domain
GPY14_RS16040	COG3428	Bacterial PH domain
GPY14_RS16045	COG0705	Rhomboid family
GPY14_RS16060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY14_RS16065	COG0864	Transcriptional regulator
GPY14_RS16070	COG2337	Toxic component of a toxin-antitoxin (TA) module
GPY14_RS16075	COG1366	Belongs to the anti-sigma-factor antagonist family
GPY14_RS16080	COG1366	Belongs to the anti-sigma-factor antagonist family
GPY14_RS16085	COG2172	sigma factor antagonist activity
GPY14_RS16090	COG2208	phosphoserine phosphatase activity
GPY14_RS16095	COG1366	Belongs to the anti-sigma-factor antagonist family
GPY14_RS16105	COG1191	sigma factor activity
GPY14_RS16110	COG2208	phosphoserine phosphatase activity
GPY14_RS16165	COG0582	viral genome integration into host DNA
GPY14_RS16170	COG2856	Zn peptidase
GPY14_RS16175	COG1396	sequence-specific DNA binding
GPY14_RS16200	COG1674	ftsk spoiiie
GPY14_RS16205	COG2946	Replication initiation factor
GPY14_RS16240	COG0433	COG0433 Predicted ATPase
GPY14_RS16255	COG0791	NLP P60 protein
GPY14_RS16255	COG0741	lytic transglycosylase activity
GPY14_RS16285	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY14_RS16295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY14_RS16300	COG0477	Major facilitator Superfamily
GPY14_RS16315	COG2030	dehydratase
GPY14_RS16330	COG1959	2 iron, 2 sulfur cluster binding
GPY14_RS16335	COG2910	NAD(P)H-binding
GPY14_RS16340	COG3239	Fatty acid desaturase
GPY14_RS16350	COG1278	Cold shock
GPY14_RS16355	COG1329	Transcriptional regulator
GPY14_RS16360	COG1794	racemase activity, acting on amino acids and derivatives
GPY14_RS16375	COG3621	Patatin-like phospholipase
GPY14_RS16385	COG0662	Cupin 2, conserved barrel domain protein
GPY14_RS16400	COG0277	FAD linked oxidase domain protein
GPY14_RS16425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPY14_RS16450	COG1064	alcohol dehydrogenase
GPY14_RS16455	COG0789	Transcriptional regulator
GPY14_RS16465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY14_RS16480	COG2814	Major facilitator Superfamily
GPY14_RS16485	COG1309	transcriptional regulator
GPY14_RS16490	COG0697	spore germination
GPY14_RS16495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY14_RS16500	COG5577	PFAM Coat F domain
GPY14_RS16510	COG1063	alcohol dehydrogenase
GPY14_RS16515	COG5577	PFAM Coat F domain
GPY14_RS16525	COG4585	Histidine kinase
GPY14_RS16530	COG2197	response regulator
GPY14_RS16535	COG2409	Drug exporters of the RND superfamily
GPY14_RS16540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GPY14_RS16550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY14_RS16555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY14_RS16565	COG2814	Major facilitator Superfamily
GPY14_RS16580	COG0730	response to heat
GPY14_RS16585	COG0456	acetyltransferase
GPY14_RS16590	COG4978	Transcriptional regulator
GPY14_RS16590	COG0789	Transcriptional regulator
GPY14_RS16595	COG0697	spore germination
GPY14_RS16600	COG1051	belongs to the nudix hydrolase family
GPY14_RS16605	COG2226	methyltransferase
GPY14_RS16610	COG0473	3-isopropylmalate dehydrogenase activity
GPY14_RS16615	COG1802	Transcriptional regulator
GPY14_RS16620	COG1819	glycosyl
GPY14_RS16635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GPY14_RS16640	COG1388	LysM domain
GPY14_RS16645	COG2814	Major facilitator Superfamily
GPY14_RS16650	COG2188	Transcriptional regulator
GPY14_RS16655	COG2186	Transcriptional regulator
GPY14_RS16665	COG2076	Multidrug Resistance protein
GPY14_RS16670	COG2076	Multidrug Resistance protein
GPY14_RS16675	COG1309	transcriptional regulator
GPY14_RS16680	COG0531	amino acid
GPY14_RS16690	COG3832	glyoxalase III activity
GPY14_RS16695	COG0604	alcohol dehydrogenase
GPY14_RS16700	COG2814	Major facilitator Superfamily
GPY14_RS16740	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPY14_RS16745	COG0802	atpase or kinase
GPY14_RS16750	COG1214	PFAM Peptidase M22, glycoprotease
GPY14_RS16755	COG0456	acetyltransferase
GPY14_RS16760	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPY14_RS16765	COG0488	(ABC) transporter
GPY14_RS16780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPY14_RS16785	COG0805	protein transport
GPY14_RS16795	COG1266	CAAX protease self-immunity
GPY14_RS16800	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPY14_RS16815	COG0457	Tetratricopeptide repeat
GPY14_RS16820	COG1063	alcohol dehydrogenase
GPY14_RS16825	COG2211	Major facilitator Superfamily
GPY14_RS16830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY14_RS16840	COG1842	Phage shock protein A
GPY14_RS16845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPY14_RS16850	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GPY14_RS16855	COG4260	virion core protein, lumpy skin disease virus
GPY14_RS16860	COG2755	lipolytic protein G-D-S-L family
GPY14_RS16860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GPY14_RS16870	COG1595	DNA-templated transcription, initiation
GPY14_RS16875	COG1063	alcohol dehydrogenase
GPY14_RS16880	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPY14_RS16885	COG0823	Involved in the tonB-independent uptake of proteins
GPY14_RS16895	COG2132	Multicopper oxidase
GPY14_RS16900	COG1113	amino acid transport
GPY14_RS16905	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPY14_RS16910	COG0714	Associated with various cellular activities
GPY14_RS16915	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GPY14_RS16920	COG1305	Transglutaminase-like
GPY14_RS16945	COG2252	PERMEase
GPY14_RS16950	COG3064	Membrane
GPY14_RS16970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPY14_RS16975	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPY14_RS16980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPY14_RS16985	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GPY14_RS16990	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPY14_RS17005	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPY14_RS17015	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPY14_RS17020	COG0138	bifunctional purine biosynthesis protein purh
GPY14_RS17025	COG0151	Belongs to the GarS family
GPY14_RS17035	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GPY14_RS17040	COG1470	cell adhesion involved in biofilm formation
GPY14_RS17045	COG4496	protein, YerC YecD
GPY14_RS17050	COG0069	glutamate synthase activity
GPY14_RS17060	COG0210	DNA helicase
GPY14_RS17070	COG4851	CamS sex pheromone cAM373 precursor
GPY14_RS17075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPY14_RS17080	COG1285	pathogenesis
GPY14_RS17085	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY14_RS17105	COG1309	transcriptional regulator
GPY14_RS17110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY14_RS17115	COG1597	lipid kinase activity
GPY14_RS17120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY14_RS17130	COG1131	(ABC) transporter
GPY14_RS17150	COG5444	nuclease activity
GPY14_RS17180	COG3546	catalase activity
GPY14_RS17185	COG0454	-acetyltransferase
GPY14_RS17195	COG2323	membrane
GPY14_RS17200	COG2329	Antibiotic biosynthesis monooxygenase
GPY14_RS17205	COG0346	lactoylglutathione lyase activity
GPY14_RS17210	COG1366	Belongs to the anti-sigma-factor antagonist family
GPY14_RS17215	COG5583	Uncharacterized small protein (DUF2292)
GPY14_RS17220	COG0196	riboflavin kinase activity
GPY14_RS17225	COG0670	Belongs to the BI1 family
GPY14_RS17240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY14_RS17250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY14_RS17250	COG2124	cytochrome p450
GPY14_RS17265	COG1131	(ABC) transporter
GPY14_RS17275	COG1368	sulfuric ester hydrolase activity
GPY14_RS17280	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GPY14_RS17285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY14_RS17290	COG1442	glycosyl transferase family 8
GPY14_RS17295	COG1216	Glycosyl transferase, family 2
GPY14_RS17300	COG1442	glycosyl transferase family 8
GPY14_RS17305	COG2223	nitrite transmembrane transporter activity
GPY14_RS17310	COG0531	amino acid
GPY14_RS17315	COG1012	belongs to the aldehyde dehydrogenase family
GPY14_RS17320	COG0840	transmembrane signaling receptor activity
GPY14_RS17325	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS17330	COG0457	Tetratricopeptide repeat
GPY14_RS17330	COG0463	Glycosyl transferase, family 2
GPY14_RS17335	COG0488	(ABC) transporter
GPY14_RS17340	COG0789	Transcriptional regulator
GPY14_RS17345	COG2814	Major facilitator Superfamily
GPY14_RS17350	COG0488	(ABC) transporter
GPY14_RS17355	COG0513	Belongs to the DEAD box helicase family
GPY14_RS17360	COG0456	acetyltransferase
GPY14_RS17365	COG2130	NADP-dependent
GPY14_RS17380	COG3866	Pectate lyase
GPY14_RS17385	COG0471	metal ion transport
GPY14_RS17400	COG3290	protein histidine kinase activity
GPY14_RS17405	COG4565	transcriptional regulatory protein
GPY14_RS17410	COG3181	Tripartite tricarboxylate transporter family receptor
GPY14_RS17415	COG2851	Citrate transporter
GPY14_RS17420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY14_RS17425	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GPY14_RS17435	COG2258	MOSC domain
GPY14_RS17460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY14_RS17460	COG1263	PTS System
GPY14_RS17470	COG1368	sulfuric ester hydrolase activity
GPY14_RS17480	COG0071	Belongs to the small heat shock protein (HSP20) family
GPY14_RS17495	COG1263	PTS System
GPY14_RS17495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY14_RS17500	COG0366	Alpha amylase catalytic
GPY14_RS17505	COG2188	Transcriptional regulator
GPY14_RS17510	COG0778	Nitroreductase
GPY14_RS17525	COG0737	Belongs to the 5'-nucleotidase family
GPY14_RS17530	COG0693	protein deglycase activity
GPY14_RS17535	COG1609	Transcriptional regulator
GPY14_RS17540	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPY14_RS17550	COG2814	Major facilitator Superfamily
GPY14_RS17560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPY14_RS17565	COG4980	gas vesicle protein
GPY14_RS17575	COG0477	Major facilitator Superfamily
GPY14_RS17580	COG0387	Pfam Sodium calcium exchanger
GPY14_RS17590	COG0668	transmembrane transport
GPY14_RS17595	COG0535	radical SAM domain protein
GPY14_RS17605	COG0726	polysaccharide deacetylase
GPY14_RS17610	COG2084	Dehydrogenase
GPY14_RS17620	COG0598	Magnesium transport protein CorA
GPY14_RS17625	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GPY14_RS17630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY14_RS17640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY14_RS17645	COG4637	Psort location Cytoplasmic, score
GPY14_RS17650	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GPY14_RS17655	COG0022	dehydrogenase e1 component
GPY14_RS17660	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY14_RS17665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY14_RS17670	COG3284	Transcriptional regulator
GPY14_RS17680	COG1486	melibiose metabolic process
GPY14_RS17685	COG1737	Transcriptional regulator
GPY14_RS17690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY14_RS17690	COG1263	PTS System
GPY14_RS17695	COG1132	(ABC) transporter
GPY14_RS17700	COG1132	(ABC) transporter
GPY14_RS17705	COG2259	Doxx family
GPY14_RS17710	COG2514	catechol 2,3-dioxygenase activity
GPY14_RS17720	COG1695	Transcriptional regulator
GPY14_RS17725	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY14_RS17730	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GPY14_RS17735	COG3848	Pyruvate phosphate dikinase
GPY14_RS17735	COG0574	Belongs to the PEP-utilizing enzyme family
GPY14_RS17740	COG2732	(Barnase) inhibitor
GPY14_RS17745	COG2318	DinB family
GPY14_RS17750	COG2814	Major facilitator Superfamily
GPY14_RS17755	COG1846	Transcriptional regulator
GPY14_RS17760	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GPY14_RS17760	COG0392	lysyltransferase activity
GPY14_RS17765	COG0384	phenazine biosynthesis protein PhzF
GPY14_RS17770	COG0778	Nitroreductase
GPY14_RS17785	COG1090	epimerase
GPY14_RS17800	COG2814	Major facilitator Superfamily
GPY14_RS17810	COG3591	Belongs to the peptidase S1B family
GPY14_RS17825	COG3103	Sh3 type 3 domain protein
GPY14_RS17830	COG5658	integral membrane protein
GPY14_RS17835	COG0596	Alpha beta hydrolase
GPY14_RS17840	COG0463	Glycosyl transferase, family 2
GPY14_RS17850	COG1988	membrane-bound metal-dependent
GPY14_RS17855	COG1194	a g-specific adenine glycosylase
GPY14_RS17865	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS17885	COG1132	(ABC) transporter
GPY14_RS17890	COG4129	membrane
GPY14_RS17900	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPY14_RS17905	COG0735	belongs to the Fur family
GPY14_RS18030	COG1757	Na H antiporter
GPY14_RS18035	COG3340	Belongs to the peptidase S51 family
GPY14_RS18045	COG0277	FAD linked oxidase domain protein
GPY14_RS18055	COG0747	negative chemotaxis
GPY14_RS18060	COG0601	transmembrane transport
GPY14_RS18065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY14_RS18070	COG0444	Belongs to the ABC transporter superfamily
GPY14_RS18075	COG4608	Belongs to the ABC transporter superfamily
GPY14_RS18080	COG0753	catalase activity
GPY14_RS18090	COG1116	anion transmembrane transporter activity
GPY14_RS18095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GPY14_RS18100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPY14_RS18120	COG1476	TRANSCRIPTIONal
GPY14_RS18130	COG3382	B3 4 domain protein
GPY14_RS18135	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPY14_RS18145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GPY14_RS18150	COG0789	Transcriptional regulator
GPY14_RS18155	COG1664	Polymer-forming cytoskeletal
GPY14_RS18160	COG1664	Polymer-forming cytoskeletal
GPY14_RS18165	COG2766	serine protein kinase
GPY14_RS18175	COG1846	Transcriptional regulator
GPY14_RS18180	COG1566	PFAM secretion protein HlyD family protein
GPY14_RS18185	COG2814	Major facilitator Superfamily
GPY14_RS18190	COG0655	NAD(P)H dehydrogenase (quinone) activity
GPY14_RS18205	COG1725	Transcriptional regulator
GPY14_RS18210	COG1131	(ABC) transporter
GPY14_RS18215	COG1131	(ABC) transporter
GPY14_RS18220	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GPY14_RS18225	COG1278	Cold shock
GPY14_RS18230	COG1464	Belongs to the NlpA lipoprotein family
GPY14_RS18235	COG3706	GGDEF domain
GPY14_RS18240	COG1823	symporter activity
GPY14_RS18260	COG5577	PFAM Coat F domain
GPY14_RS18265	COG0737	Belongs to the 5'-nucleotidase family
GPY14_RS18265	COG1525	nuclease
GPY14_RS18265	COG4085	toxin activity
GPY14_RS18270	COG3764	Sortase (surface protein transpeptidase)
GPY14_RS18275	COG0564	pseudouridine synthase activity
GPY14_RS18285	COG0517	IMP dehydrogenase activity
GPY14_RS18290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY14_RS18295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPY14_RS18295	COG3153	acetyltransferase
GPY14_RS18300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPY14_RS18305	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GPY14_RS18310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPY14_RS18320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPY14_RS18325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY14_RS18335	COG2197	response regulator
GPY14_RS18340	COG0431	NADPH-dependent FMN reductase
GPY14_RS18355	COG1388	LysM domain
GPY14_RS18355	COG0791	NLP P60 protein
GPY14_RS18360	COG1959	2 iron, 2 sulfur cluster binding
GPY14_RS18365	COG0668	transmembrane transport
GPY14_RS18370	COG2719	SpoVR family
GPY14_RS18375	COG1785	Belongs to the alkaline phosphatase family
GPY14_RS18380	COG1388	LysM domain
GPY14_RS18380	COG0791	NLP P60 protein
GPY14_RS18385	COG0583	DNA-binding transcription factor activity
GPY14_RS18395	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS18400	COG0531	amino acid
GPY14_RS18405	COG0733	neurotransmitter:sodium symporter activity
GPY14_RS18420	COG1595	DNA-templated transcription, initiation
GPY14_RS18425	COG0204	Acyl-transferase
GPY14_RS18430	COG1253	flavin adenine dinucleotide binding
GPY14_RS18435	COG0789	Transcriptional regulator
GPY14_RS18440	COG0436	Aminotransferase
GPY14_RS18445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY14_RS18455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPY14_RS18460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPY14_RS18465	COG0584	glycerophosphoryl diester phosphodiesterase
GPY14_RS18475	COG0668	transmembrane transport
GPY14_RS18480	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GPY14_RS18485	COG0726	polysaccharide deacetylase
GPY14_RS18490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPY14_RS18495	COG3226	Transcriptional regulator
GPY14_RS18505	COG0589	response to stress
GPY14_RS18510	COG1132	(ABC) transporter
GPY14_RS18515	COG1132	(ABC) transporter
GPY14_RS18520	COG0702	epimerase
GPY14_RS18555	COG4335	DNA alkylation repair
GPY14_RS18560	COG0561	phosphatase activity
GPY14_RS18565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY14_RS18575	COG0475	glutathione-regulated potassium exporter activity
GPY14_RS18580	COG0490	domain, Protein
GPY14_RS18590	COG1024	Enoyl-CoA hydratase
GPY14_RS18600	COG4152	abc transporter atp-binding protein
GPY14_RS18605	COG1668	transmembrane transport
GPY14_RS18610	COG0420	3'-5' exonuclease activity
GPY14_RS18630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY14_RS18665	COG4980	gas vesicle protein
GPY14_RS18680	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPY14_RS18685	COG0537	adenosine 5'-monophosphoramidase activity
GPY14_RS18690	COG1131	(ABC) transporter
GPY14_RS18695	COG4473	ABC transporter
GPY14_RS18705	COG1473	amidohydrolase
GPY14_RS18710	COG3069	C4-dicarboxylate transmembrane transporter activity
GPY14_RS18715	COG2329	Antibiotic biosynthesis monooxygenase
GPY14_RS18720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY14_RS18740	COG1309	transcriptional regulator
GPY14_RS18745	COG1511	domain protein
GPY14_RS18750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY14_RS18760	COG1363	Peptidase, m42
GPY14_RS18765	COG1301	dicarboxylic acid transport
GPY14_RS18775	COG1234	tRNA 3'-trailer cleavage
GPY14_RS18780	COG0095	Lipoate-protein ligase
GPY14_RS18785	COG0702	epimerase
GPY14_RS18790	COG0318	PFAM AMP-dependent synthetase and ligase
GPY14_RS18800	COG0501	Belongs to the peptidase M48B family
GPY14_RS18805	COG1404	Belongs to the peptidase S8 family
GPY14_RS18815	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GPY14_RS18820	COG0406	alpha-ribazole phosphatase activity
GPY14_RS18825	COG0183	Belongs to the thiolase family
GPY14_RS18830	COG0318	PFAM AMP-dependent synthetase and ligase
GPY14_RS18835	COG1268	BioY protein
GPY14_RS18840	COG0840	transmembrane signaling receptor activity
GPY14_RS18845	COG0723	plastoquinol--plastocyanin reductase activity
GPY14_RS18845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY14_RS18850	COG1028	Short-chain dehydrogenase reductase Sdr
GPY14_RS18860	COG4903	ComK protein
GPY14_RS18870	COG5646	InterPro IPR014922
GPY14_RS18895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY14_RS18910	COG0398	Pfam SNARE associated Golgi protein
GPY14_RS18915	COG0681	Belongs to the peptidase S26 family
GPY14_RS18920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY14_RS18925	COG1846	Transcriptional regulator
GPY14_RS18930	COG3180	Ammonia monooxygenase
GPY14_RS18935	COG2814	Major facilitator Superfamily
GPY14_RS18945	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GPY14_RS18965	COG0420	3'-5' exonuclease activity
GPY14_RS18970	COG0419	ATPase involved in DNA repair
GPY14_RS18975	COG1403	HNH endonuclease
GPY14_RS19015	COG0179	Fumarylacetoacetate (FAA) hydrolase
GPY14_RS19035	COG0367	asparagine synthase
GPY14_RS19040	COG1562	ergosterol biosynthetic process
GPY14_RS19045	COG0534	Mate efflux family protein
GPY14_RS19055	COG2318	DinB family
GPY14_RS19060	COG1279	arginine transmembrane transporter activity
GPY14_RS19065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY14_RS19070	COG1357	PFAM Pentapeptide repeats (8 copies)
GPY14_RS19075	COG2153	protein acetylation
GPY14_RS19080	COG0646	methionine synthase
GPY14_RS19080	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPY14_RS19090	COG2996	Protein conserved in bacteria
GPY14_RS19100	COG0840	transmembrane signaling receptor activity
GPY14_RS19105	COG2124	cytochrome p450
GPY14_RS19115	COG1307	EDD domain protein, DegV family
GPY14_RS19120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY14_RS19135	COG0561	phosphatase activity
GPY14_RS19145	COG2151	metal-sulfur cluster biosynthetic enzyme
GPY14_RS19155	COG0277	FAD linked oxidase domain protein
GPY14_RS19180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPY14_RS19185	COG0505	Belongs to the CarA family
GPY14_RS19190	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GPY14_RS19195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPY14_RS19210	COG2267	carboxylic ester hydrolase activity
GPY14_RS19220	COG1744	ABC transporter substrate-binding protein PnrA-like
GPY14_RS19235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY14_RS19240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY14_RS19245	COG5504	Zn-dependent protease
GPY14_RS19250	COG0444	Belongs to the ABC transporter superfamily
GPY14_RS19255	COG4608	Belongs to the ABC transporter superfamily
GPY14_RS19265	COG0601	transmembrane transport
GPY14_RS19270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY14_RS19280	COG0180	Tryptophanyl-tRNA synthetase
GPY14_RS19285	COG4166	transmembrane transport
GPY14_RS19290	COG0601	transmembrane transport
GPY14_RS19295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY14_RS19300	COG0444	Belongs to the ABC transporter superfamily
GPY14_RS19305	COG4608	Belongs to the ABC transporter superfamily
GPY14_RS19315	COG0456	acetyltransferase
GPY14_RS19320	COG1393	Belongs to the ArsC family
GPY14_RS19325	COG0861	Integral membrane protein TerC family
GPY14_RS19330	COG4862	establishment of competence for transformation
GPY14_RS19335	COG4469	Competence protein
GPY14_RS19340	COG1164	Oligoendopeptidase f
GPY14_RS19350	COG2346	COG2346, Truncated hemoglobins
GPY14_RS19355	COG0741	lytic transglycosylase activity
GPY14_RS19360	COG4116	CYTH
GPY14_RS19370	COG2357	RelA SpoT domain protein
GPY14_RS19375	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPY14_RS19395	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GPY14_RS19400	COG0352	thiamine-phosphate diphosphorylase activity
GPY14_RS19405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY14_RS19410	COG2104	thiamine diphosphate biosynthetic process
GPY14_RS19420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY14_RS19425	COG0351	phosphomethylpyrimidine kinase
GPY14_RS19430	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPY14_RS19485	COG0210	DNA helicase
GPY14_RS19505	COG1131	(ABC) transporter
GPY14_RS19515	COG2153	protein acetylation
GPY14_RS19525	COG2382	esterase
GPY14_RS19530	COG0626	cystathionine gamma-synthase activity
GPY14_RS19535	COG0626	cystathionine gamma-synthase activity
GPY14_RS19580	COG5632	N-Acetylmuramoyl-L-alanine amidase
GPY14_RS19580	COG3409	Peptidoglycan-binding domain 1 protein
GPY14_RS19580	COG1388	LysM domain
GPY14_RS19650	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity