locus-tag	class	description
EG219_RS00010	COG0592	DNA-directed DNA polymerase activity
EG219_RS00015	COG2501	S4 domain
EG219_RS00030	COG0187	DNA topoisomerase II activity
EG219_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EG219_RS00060	COG0517	IMP dehydrogenase activity
EG219_RS00060	COG0516	GMP reductase activity
EG219_RS00065	COG1686	Belongs to the peptidase S11 family
EG219_RS00085	COG1929	Belongs to the glycerate kinase type-1 family
EG219_RS00095	COG1428	Deoxynucleoside kinase
EG219_RS00100	COG1428	Deoxynucleoside kinase
EG219_RS00105	COG1388	LysM domain
EG219_RS00105	COG3858	chitin binding
EG219_RS00110	COG1335	isochorismatase
EG219_RS00115	COG0590	tRNA wobble adenosine to inosine editing
EG219_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EG219_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EG219_RS00180	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
EG219_RS00185	COG3853	Toxic anion resistance protein (TelA)
EG219_RS00190	COG1982	Orn Lys Arg decarboxylase major
EG219_RS00200	COG3870	Protein conserved in bacteria
EG219_RS00205	COG1728	Protein conserved in bacteria
EG219_RS00210	COG0470	DNA polymerase III
EG219_RS00215	COG1774	PSP1 C-terminal conserved region
EG219_RS00225	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EG219_RS00235	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EG219_RS00240	COG2002	toxin-antitoxin pair type II binding
EG219_RS00245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG219_RS00245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG219_RS00250	COG0084	hydrolase, TatD family'
EG219_RS00255	COG3584	3D domain protein
EG219_RS00255	COG3583	domain protein
EG219_RS00260	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EG219_RS00265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EG219_RS00275	COG4466	Protein conserved in bacteria
EG219_RS00290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EG219_RS00295	COG0251	oxidation-reduction process
EG219_RS00310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EG219_RS00330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EG219_RS00335	COG2002	toxin-antitoxin pair type II binding
EG219_RS00340	COG2244	polysaccharide biosynthetic process
EG219_RS00345	COG3956	TIGRFAM MazG family protein
EG219_RS00350	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EG219_RS00365	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EG219_RS00370	COG1098	S1 RNA binding domain
EG219_RS00385	COG2208	phosphoserine phosphatase activity
EG219_RS00390	COG2304	oxidoreductase activity
EG219_RS00395	COG0515	serine threonine protein kinase
EG219_RS00400	COG0037	tRNA processing
EG219_RS00405	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EG219_RS00410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EG219_RS00425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EG219_RS00430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EG219_RS00435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EG219_RS00440	COG0512	Glutamine amidotransferase of anthranilate synthase
EG219_RS00445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EG219_RS00450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EG219_RS00455	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EG219_RS00460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EG219_RS00465	COG1396	sequence-specific DNA binding
EG219_RS00470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EG219_RS00475	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EG219_RS00505	COG4463	regulation of RNA biosynthetic process
EG219_RS00510	COG3880	PFAM UvrB UvrC protein
EG219_RS00520	COG0542	response to heat
EG219_RS00525	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EG219_RS00530	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EG219_RS00535	COG4956	integral membrane protein (PIN domain superfamily)
EG219_RS00555	COG1045	serine acetyltransferase
EG219_RS00565	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EG219_RS00570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EG219_RS00575	COG3688	RNA-binding protein containing a PIN domain
EG219_RS00580	COG1595	DNA-templated transcription, initiation
EG219_RS00590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EG219_RS00595	COG0250	Participates in transcription elongation, termination and antitermination
EG219_RS00620	COG2813	Specifically methylates the guanine in position
EG219_RS00635	COG1358	cellular component organization or biogenesis
EG219_RS00660	COG0596	Alpha beta hydrolase
EG219_RS00770	COG0201	protein transport
EG219_RS00780	COG0024	Methionine aminopeptidase
EG219_RS00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EG219_RS00820	COG1122	ATPase activity
EG219_RS00825	COG1122	ATPase activity
EG219_RS00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EG219_RS00850	COG2226	methyltransferase
EG219_RS00855	COG2318	DinB family
EG219_RS00865	COG0860	N-Acetylmuramoyl-L-alanine amidase
EG219_RS00870	COG0489	protein tyrosine kinase activity
EG219_RS00880	COG2194	sulfuric ester hydrolase activity
EG219_RS00885	COG0726	polysaccharide deacetylase
EG219_RS00905	COG0738	Major facilitator superfamily
EG219_RS00910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EG219_RS00925	COG0659	secondary active sulfate transmembrane transporter activity
EG219_RS00930	COG0385	Bile acid
EG219_RS00935	COG2819	hydrolase of the alpha beta superfamily
EG219_RS00940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EG219_RS00945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EG219_RS00950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EG219_RS00955	COG2207	Transcriptional regulator
EG219_RS00955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EG219_RS00960	COG3876	Protein conserved in bacteria
EG219_RS00965	COG1472	Belongs to the glycosyl hydrolase 3 family
EG219_RS00970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EG219_RS00975	COG1263	PTS System
EG219_RS00975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EG219_RS00985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EG219_RS00990	COG1683	Conserved Protein
EG219_RS01020	COG1595	DNA-templated transcription, initiation
EG219_RS01025	COG5662	AntiSigma factor
EG219_RS01030	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EG219_RS01035	COG4856	YbbR-like protein
EG219_RS01070	COG1346	cytolysis
EG219_RS01075	COG1380	Effector of murein hydrolase LrgA
EG219_RS01080	COG1846	Transcriptional regulator
EG219_RS01085	COG1113	amino acid transport
EG219_RS01090	COG1011	Hydrolase
EG219_RS01095	COG4585	Histidine kinase
EG219_RS01100	COG2197	response regulator
EG219_RS01105	COG1131	(ABC) transporter
EG219_RS01145	COG0531	amino acid
EG219_RS01150	COG0584	glycerophosphoryl diester phosphodiesterase
EG219_RS01155	COG2271	Major facilitator Superfamily
EG219_RS01170	COG2368	4-hydroxyphenylacetate
EG219_RS01180	COG3409	Peptidoglycan-binding domain 1 protein
EG219_RS01195	COG0371	Dehydrogenase
EG219_RS01205	COG1183	phosphatidylcholine synthase activity
EG219_RS01210	COG0586	Pfam SNARE associated Golgi protein
EG219_RS01215	COG0688	phosphatidylethanolamine metabolic process
EG219_RS01230	COG1301	dicarboxylic acid transport
EG219_RS01235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EG219_RS01240	COG0833	amino acid
EG219_RS01245	COG2040	homocysteine
EG219_RS01250	COG1115	amino acid carrier protein
EG219_RS01255	COG2066	Belongs to the glutaminase family
EG219_RS01260	COG4191	Histidine kinase
EG219_RS01265	COG0784	Response regulator, receiver
EG219_RS01275	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EG219_RS01280	COG0778	Nitroreductase
EG219_RS01285	COG0346	lactoylglutathione lyase activity
EG219_RS01290	COG2259	Doxx family
EG219_RS01295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG219_RS01310	COG3773	Cell wall hydrolase
EG219_RS01320	COG3540	Alkaline phosphatase
EG219_RS01325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EG219_RS01330	COG0805	protein transport
EG219_RS01340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EG219_RS01345	COG0477	Major facilitator Superfamily
EG219_RS01350	COG1309	transcriptional regulator
EG219_RS01355	COG0252	asparaginase activity
EG219_RS01360	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EG219_RS01365	COG1405	negative regulation of cell septum assembly
EG219_RS01365	COG3012	SEC-C Motif Domain Protein
EG219_RS01370	COG0667	Aldo Keto reductase
EG219_RS01380	COG1595	DNA-templated transcription, initiation
EG219_RS01385	COG1595	DNA-templated transcription, initiation
EG219_RS01390	COG1876	peptidase activity
EG219_RS01395	COG0457	Tetratricopeptide repeat
EG219_RS01400	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS01405	COG0366	Alpha amylase catalytic
EG219_RS01410	COG0803	Belongs to the bacterial solute-binding protein 9 family
EG219_RS01415	COG1121	(ABC) transporter
EG219_RS01420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EG219_RS01425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EG219_RS01430	COG2310	stress, protein
EG219_RS01435	COG2310	stress, protein
EG219_RS01440	COG2310	stress, protein
EG219_RS01445	COG0861	Integral membrane protein TerC family
EG219_RS01455	COG3853	Toxic anion resistance protein (TelA)
EG219_RS01460	COG0477	Major facilitator Superfamily
EG219_RS01465	COG0517	IMP dehydrogenase activity
EG219_RS01465	COG4175	Glycine betaine
EG219_RS01470	COG4176	ABC-type proline glycine betaine transport system permease component
EG219_RS01475	COG2113	Glycine betaine
EG219_RS01480	COG1473	amidohydrolase
EG219_RS01485	COG1288	antiporter activity
EG219_RS01495	COG0366	Alpha amylase catalytic
EG219_RS01505	COG2814	Major facilitator Superfamily
EG219_RS01510	COG1846	Transcriptional regulator
EG219_RS01515	COG1280	lysine exporter protein (LysE YggA)
EG219_RS01520	COG3403	YqcI/YcgG family
EG219_RS01525	COG1113	amino acid transport
EG219_RS01530	COG3665	Urea carboxylase-associated protein
EG219_RS01545	COG1660	Displays ATPase and GTPase activities
EG219_RS01550	COG1082	Xylose isomerase domain protein TIM barrel
EG219_RS01555	COG2271	Major facilitator Superfamily
EG219_RS01560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EG219_RS01565	COG3458	cephalosporin-C deacetylase activity
EG219_RS01570	COG3541	Predicted nucleotidyltransferase
EG219_RS01575	COG0506	proline dehydrogenase activity
EG219_RS01580	COG1012	belongs to the aldehyde dehydrogenase family
EG219_RS01585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EG219_RS01590	COG2508	Transcriptional regulator
EG219_RS01600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EG219_RS01600	COG1587	Uroporphyrinogen-III synthase
EG219_RS01605	COG2146	nitrite reductase [NAD(P)H] activity
EG219_RS01610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EG219_RS01620	COG0523	cobalamin synthesis protein
EG219_RS01625	COG1063	alcohol dehydrogenase
EG219_RS01630	COG1714	RDD family
EG219_RS01640	COG2723	6-phospho-beta-galactosidase activity
EG219_RS01640	COG2723	6-phospho-beta-galactosidase activity
EG219_RS01650	COG3209	COG3209 Rhs family protein
EG219_RS01655	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EG219_RS01660	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EG219_RS01665	COG1733	regulation of RNA biosynthetic process
EG219_RS01680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS01685	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EG219_RS01700	COG2364	Membrane
EG219_RS01705	COG1126	abc transporter atp-binding protein
EG219_RS01710	COG0765	amino acid transport
EG219_RS01715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EG219_RS01720	COG0583	DNA-binding transcription factor activity
EG219_RS01725	COG0163	prenyltransferase activity
EG219_RS01730	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EG219_RS01745	COG3104	oligopeptide transport
EG219_RS01750	COG5434	Belongs to the glycosyl hydrolase 28 family
EG219_RS01760	COG0697	spore germination
EG219_RS01770	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EG219_RS01775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EG219_RS01780	COG0456	acetyltransferase
EG219_RS01785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EG219_RS01790	COG0765	amino acid transport
EG219_RS01795	COG1126	abc transporter atp-binding protein
EG219_RS01800	COG1473	amidohydrolase
EG219_RS01805	COG2079	MmgE PrpD family protein
EG219_RS01810	COG1136	(ABC) transporter
EG219_RS01815	COG0577	efflux transmembrane transporter activity
EG219_RS01820	COG0745	RESPONSE REGULATOR receiver
EG219_RS01825	COG5002	protein histidine kinase activity
EG219_RS01825	COG3850	Histidine kinase
EG219_RS01830	COG0457	Tetratricopeptide repeat
EG219_RS01845	COG0527	aspartate kinase activity
EG219_RS01850	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EG219_RS01855	COG4605	iron ion homeostasis
EG219_RS01860	COG4604	ABC transporter, ATP-binding protein
EG219_RS01865	COG4607	ABC-type enterochelin transport system periplasmic component
EG219_RS01870	COG2814	Major facilitator Superfamily
EG219_RS01875	COG1309	transcriptional regulator
EG219_RS01880	COG0778	Nitroreductase
EG219_RS01885	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EG219_RS01890	COG0640	Transcriptional regulator
EG219_RS01895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EG219_RS01900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EG219_RS01905	COG1012	belongs to the aldehyde dehydrogenase family
EG219_RS01910	COG4975	Glucose uptake
EG219_RS01915	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS01920	COG4549	nuclear export factor GLE1
EG219_RS01925	COG2372	response to copper ion
EG219_RS01925	COG1276	copper resistance
EG219_RS01930	COG1349	DNA-binding transcription factor activity
EG219_RS01940	COG2213	PTS system mannitol-specific
EG219_RS01945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EG219_RS01955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EG219_RS01965	COG0561	phosphatase activity
EG219_RS01975	COG1914	H( )-stimulated, divalent metal cation uptake system
EG219_RS01985	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EG219_RS01990	COG1984	allophanate hydrolase subunit 2
EG219_RS01995	COG1414	Transcriptional regulator
EG219_RS02000	COG2755	lipolytic protein G-D-S-L family
EG219_RS02010	COG2329	Antibiotic biosynthesis monooxygenase
EG219_RS02015	COG0768	penicillin binding
EG219_RS02020	COG4989	oxidoreductase activity
EG219_RS02025	COG3711	transcriptional antiterminator
EG219_RS02030	COG0318	PFAM AMP-dependent synthetase and ligase
EG219_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS02040	COG1917	Cupin 2, conserved barrel domain protein
EG219_RS02045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EG219_RS02050	COG3871	stress protein (general stress protein 26)
EG219_RS02060	COG2814	Major facilitator Superfamily
EG219_RS02065	COG1522	sequence-specific DNA binding
EG219_RS02070	COG0551	DNA topoisomerase type I activity
EG219_RS02070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EG219_RS02075	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EG219_RS02080	COG3706	GGDEF domain
EG219_RS02085	COG5298	Protein conserved in bacteria
EG219_RS02090	COG1215	transferase activity, transferring glycosyl groups
EG219_RS02100	COG0531	amino acid
EG219_RS02105	COG0494	nUDIX hydrolase
EG219_RS02110	COG0028	Belongs to the TPP enzyme family
EG219_RS02155	COG1914	H( )-stimulated, divalent metal cation uptake system
EG219_RS02170	COG4876	unkown
EG219_RS02180	COG2076	Multidrug Resistance protein
EG219_RS02185	COG2217	Heavy metal translocating P-type atpase
EG219_RS02190	COG3729	General stress protein
EG219_RS02195	COG0662	Cupin 2, conserved barrel domain protein
EG219_RS02200	COG2329	Antibiotic biosynthesis monooxygenase
EG219_RS02205	COG3546	catalase activity
EG219_RS02210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EG219_RS02215	COG3290	protein histidine kinase activity
EG219_RS02220	COG4565	transcriptional regulatory protein
EG219_RS02225	COG1301	dicarboxylic acid transport
EG219_RS02230	COG0628	permease
EG219_RS02235	COG1131	(ABC) transporter
EG219_RS02240	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EG219_RS02250	COG1960	acyl-CoA dehydrogenase activity
EG219_RS02265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EG219_RS02270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG219_RS02280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EG219_RS02285	COG0513	Belongs to the DEAD box helicase family
EG219_RS02290	COG3402	PFAM membrane-flanked domain
EG219_RS02295	COG3428	Bacterial PH domain
EG219_RS02300	COG0705	Rhomboid family
EG219_RS02310	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EG219_RS02315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EG219_RS02320	COG0864	Transcriptional regulator
EG219_RS02325	COG2337	Toxic component of a toxin-antitoxin (TA) module
EG219_RS02330	COG1366	Belongs to the anti-sigma-factor antagonist family
EG219_RS02335	COG1366	Belongs to the anti-sigma-factor antagonist family
EG219_RS02340	COG2172	sigma factor antagonist activity
EG219_RS02345	COG2208	phosphoserine phosphatase activity
EG219_RS02350	COG1366	Belongs to the anti-sigma-factor antagonist family
EG219_RS02360	COG1191	sigma factor activity
EG219_RS02365	COG2208	phosphoserine phosphatase activity
EG219_RS02370	COG2183	response to ionizing radiation
EG219_RS02420	COG2249	NAD(P)H dehydrogenase (quinone) activity
EG219_RS02430	COG0477	Major facilitator Superfamily
EG219_RS02435	COG1846	Transcriptional regulator
EG219_RS02445	COG1959	2 iron, 2 sulfur cluster binding
EG219_RS02450	COG2910	NAD(P)H-binding
EG219_RS02455	COG1278	Cold shock
EG219_RS02465	COG1794	racemase activity, acting on amino acids and derivatives
EG219_RS02480	COG3621	Patatin-like phospholipase
EG219_RS02500	COG0277	FAD linked oxidase domain protein
EG219_RS02520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EG219_RS02545	COG1064	alcohol dehydrogenase
EG219_RS02550	COG0789	Transcriptional regulator
EG219_RS02560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EG219_RS02575	COG2814	Major facilitator Superfamily
EG219_RS02580	COG1309	transcriptional regulator
EG219_RS02585	COG5577	PFAM Coat F domain
EG219_RS02595	COG1063	alcohol dehydrogenase
EG219_RS02600	COG5577	PFAM Coat F domain
EG219_RS02610	COG4585	Histidine kinase
EG219_RS02615	COG2197	response regulator
EG219_RS02620	COG2409	Drug exporters of the RND superfamily
EG219_RS02625	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EG219_RS02630	COG0488	(ABC) transporter
EG219_RS02635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EG219_RS02640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EG219_RS02650	COG2814	Major facilitator Superfamily
EG219_RS02655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EG219_RS02665	COG0730	response to heat
EG219_RS02670	COG0456	acetyltransferase
EG219_RS02675	COG0789	Transcriptional regulator
EG219_RS02675	COG4978	Transcriptional regulator
EG219_RS02680	COG0697	spore germination
EG219_RS02685	COG1051	belongs to the nudix hydrolase family
EG219_RS02690	COG0473	3-isopropylmalate dehydrogenase activity
EG219_RS02695	COG1802	Transcriptional regulator
EG219_RS02700	COG1819	glycosyl
EG219_RS02715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EG219_RS02720	COG1388	LysM domain
EG219_RS02725	COG2814	Major facilitator Superfamily
EG219_RS02730	COG2188	Transcriptional regulator
EG219_RS02735	COG2186	Transcriptional regulator
EG219_RS02740	COG2807	transmembrane transport
EG219_RS02745	COG2076	Multidrug Resistance protein
EG219_RS02750	COG2076	Multidrug Resistance protein
EG219_RS02755	COG1309	transcriptional regulator
EG219_RS02760	COG0531	amino acid
EG219_RS02770	COG3832	glyoxalase III activity
EG219_RS02775	COG0604	alcohol dehydrogenase
EG219_RS02780	COG2814	Major facilitator Superfamily
EG219_RS02830	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EG219_RS02835	COG0802	atpase or kinase
EG219_RS02840	COG1214	PFAM Peptidase M22, glycoprotease
EG219_RS02845	COG0456	acetyltransferase
EG219_RS02850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EG219_RS02855	COG0488	(ABC) transporter
EG219_RS02870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EG219_RS02875	COG0805	protein transport
EG219_RS02885	COG1266	CAAX protease self-immunity
EG219_RS02900	COG0457	Tetratricopeptide repeat
EG219_RS02905	COG1063	alcohol dehydrogenase
EG219_RS02910	COG2211	Major facilitator Superfamily
EG219_RS02915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EG219_RS02925	COG1842	Phage shock protein A
EG219_RS02930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EG219_RS02935	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EG219_RS02940	COG4260	virion core protein, lumpy skin disease virus
EG219_RS02945	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EG219_RS02945	COG2755	lipolytic protein G-D-S-L family
EG219_RS02955	COG1595	DNA-templated transcription, initiation
EG219_RS02960	COG1063	alcohol dehydrogenase
EG219_RS02965	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EG219_RS02970	COG0823	Involved in the tonB-independent uptake of proteins
EG219_RS02980	COG2132	Multicopper oxidase
EG219_RS02985	COG1113	amino acid transport
EG219_RS02990	COG0714	Associated with various cellular activities
EG219_RS02995	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EG219_RS03000	COG1305	Transglutaminase-like
EG219_RS03020	COG2252	PERMEase
EG219_RS03025	COG3064	Membrane
EG219_RS03045	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EG219_RS03050	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EG219_RS03055	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EG219_RS03060	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EG219_RS03065	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EG219_RS03080	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EG219_RS03090	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EG219_RS03095	COG0138	bifunctional purine biosynthesis protein purh
EG219_RS03100	COG0151	Belongs to the GarS family
EG219_RS03110	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EG219_RS03115	COG1470	cell adhesion involved in biofilm formation
EG219_RS03120	COG4496	protein, YerC YecD
EG219_RS03125	COG0069	glutamate synthase activity
EG219_RS03135	COG0210	DNA helicase
EG219_RS03145	COG4851	CamS sex pheromone cAM373 precursor
EG219_RS03150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EG219_RS03155	COG1285	pathogenesis
EG219_RS03160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EG219_RS03180	COG1309	transcriptional regulator
EG219_RS03185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EG219_RS03190	COG1597	lipid kinase activity
EG219_RS03195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EG219_RS03230	COG3546	catalase activity
EG219_RS03235	COG0454	-acetyltransferase
EG219_RS03245	COG2323	membrane
EG219_RS03250	COG2329	Antibiotic biosynthesis monooxygenase
EG219_RS03255	COG0346	lactoylglutathione lyase activity
EG219_RS03265	COG1366	Belongs to the anti-sigma-factor antagonist family
EG219_RS03270	COG5583	Uncharacterized small protein (DUF2292)
EG219_RS03275	COG0196	riboflavin kinase activity
EG219_RS03280	COG0670	Belongs to the BI1 family
EG219_RS03285	COG1846	Transcriptional regulator
EG219_RS03290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EG219_RS03300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EG219_RS03300	COG2124	cytochrome p450
EG219_RS03305	COG1368	sulfuric ester hydrolase activity
EG219_RS03310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EG219_RS03315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EG219_RS03320	COG1442	glycosyl transferase family 8
EG219_RS03325	COG1216	Glycosyl transferase, family 2
EG219_RS03330	COG1442	glycosyl transferase family 8
EG219_RS03335	COG2223	nitrite transmembrane transporter activity
EG219_RS03340	COG0531	amino acid
EG219_RS03345	COG1012	belongs to the aldehyde dehydrogenase family
EG219_RS03350	COG0840	transmembrane signaling receptor activity
EG219_RS03355	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS03360	COG0457	Tetratricopeptide repeat
EG219_RS03360	COG0463	Glycosyl transferase, family 2
EG219_RS03365	COG0488	(ABC) transporter
EG219_RS03370	COG0789	Transcriptional regulator
EG219_RS03375	COG2814	Major facilitator Superfamily
EG219_RS03380	COG0488	(ABC) transporter
EG219_RS03385	COG0513	Belongs to the DEAD box helicase family
EG219_RS03390	COG0456	acetyltransferase
EG219_RS03395	COG2130	NADP-dependent
EG219_RS03410	COG3866	Pectate lyase
EG219_RS03415	COG0471	metal ion transport
EG219_RS03440	COG3290	protein histidine kinase activity
EG219_RS03445	COG4565	transcriptional regulatory protein
EG219_RS03450	COG3181	Tripartite tricarboxylate transporter family receptor
EG219_RS03455	COG2851	Citrate transporter
EG219_RS03460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG219_RS03465	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EG219_RS03475	COG2258	MOSC domain
EG219_RS03495	COG0024	Methionine aminopeptidase
EG219_RS03500	COG1263	PTS System
EG219_RS03500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EG219_RS03510	COG1368	sulfuric ester hydrolase activity
EG219_RS03520	COG0071	Belongs to the small heat shock protein (HSP20) family
EG219_RS03535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EG219_RS03535	COG1263	PTS System
EG219_RS03540	COG0366	Alpha amylase catalytic
EG219_RS03545	COG2188	Transcriptional regulator
EG219_RS03550	COG0778	Nitroreductase
EG219_RS03565	COG0737	Belongs to the 5'-nucleotidase family
EG219_RS03570	COG0693	protein deglycase activity
EG219_RS03575	COG1609	Transcriptional regulator
EG219_RS03590	COG2814	Major facilitator Superfamily
EG219_RS03600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EG219_RS03605	COG4980	gas vesicle protein
EG219_RS03610	COG1295	ribonuclease BN
EG219_RS03620	COG0477	Major facilitator Superfamily
EG219_RS03625	COG0387	Pfam Sodium calcium exchanger
EG219_RS03635	COG0668	transmembrane transport
EG219_RS03640	COG0535	radical SAM domain protein
EG219_RS03650	COG0726	polysaccharide deacetylase
EG219_RS03655	COG2084	Dehydrogenase
EG219_RS03665	COG0598	Magnesium transport protein CorA
EG219_RS03670	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EG219_RS03675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EG219_RS03685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EG219_RS03695	COG4637	Psort location Cytoplasmic, score
EG219_RS03700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EG219_RS03705	COG0022	dehydrogenase e1 component
EG219_RS03710	COG0508	dehydrogenase complex catalyzes the overall conversion of
EG219_RS03715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EG219_RS03720	COG3284	Transcriptional regulator
EG219_RS03730	COG1486	melibiose metabolic process
EG219_RS03735	COG1737	Transcriptional regulator
EG219_RS03740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EG219_RS03740	COG1263	PTS System
EG219_RS03745	COG1132	(ABC) transporter
EG219_RS03750	COG1132	(ABC) transporter
EG219_RS03755	COG2259	Doxx family
EG219_RS03760	COG2514	catechol 2,3-dioxygenase activity
EG219_RS03775	COG1695	Transcriptional regulator
EG219_RS03780	COG2249	NAD(P)H dehydrogenase (quinone) activity
EG219_RS03785	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EG219_RS03790	COG0574	Belongs to the PEP-utilizing enzyme family
EG219_RS03790	COG3848	Pyruvate phosphate dikinase
EG219_RS03795	COG2732	(Barnase) inhibitor
EG219_RS03800	COG2318	DinB family
EG219_RS03805	COG2814	Major facilitator Superfamily
EG219_RS03810	COG1846	Transcriptional regulator
EG219_RS03815	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EG219_RS03815	COG0392	lysyltransferase activity
EG219_RS03820	COG0384	phenazine biosynthesis protein PhzF
EG219_RS03825	COG0778	Nitroreductase
EG219_RS03840	COG1090	epimerase
EG219_RS03855	COG2814	Major facilitator Superfamily
EG219_RS03865	COG3591	Belongs to the peptidase S1B family
EG219_RS03880	COG3103	Sh3 type 3 domain protein
EG219_RS03885	COG5658	integral membrane protein
EG219_RS03890	COG0596	Alpha beta hydrolase
EG219_RS03895	COG0463	Glycosyl transferase, family 2
EG219_RS03900	COG4485	Bacterial membrane protein, YfhO
EG219_RS03905	COG1988	membrane-bound metal-dependent
EG219_RS03910	COG1194	a g-specific adenine glycosylase
EG219_RS03920	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS03940	COG1132	(ABC) transporter
EG219_RS03945	COG4129	membrane
EG219_RS03955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EG219_RS03960	COG0735	belongs to the Fur family
EG219_RS04085	COG3340	Belongs to the peptidase S51 family
EG219_RS04095	COG0277	FAD linked oxidase domain protein
EG219_RS04105	COG0747	negative chemotaxis
EG219_RS04110	COG0601	transmembrane transport
EG219_RS04115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EG219_RS04120	COG0444	Belongs to the ABC transporter superfamily
EG219_RS04125	COG4608	Belongs to the ABC transporter superfamily
EG219_RS04130	COG0753	catalase activity
EG219_RS04145	COG1116	anion transmembrane transporter activity
EG219_RS04150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EG219_RS04155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EG219_RS04175	COG1476	TRANSCRIPTIONal
EG219_RS04185	COG3382	B3 4 domain protein
EG219_RS04190	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EG219_RS04200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EG219_RS04205	COG0789	Transcriptional regulator
EG219_RS04210	COG1664	Polymer-forming cytoskeletal
EG219_RS04215	COG1664	Polymer-forming cytoskeletal
EG219_RS04220	COG2766	serine protein kinase
EG219_RS04235	COG1846	Transcriptional regulator
EG219_RS04240	COG1566	PFAM secretion protein HlyD family protein
EG219_RS04245	COG2814	Major facilitator Superfamily
EG219_RS04250	COG0655	NAD(P)H dehydrogenase (quinone) activity
EG219_RS04265	COG1725	Transcriptional regulator
EG219_RS04270	COG1131	(ABC) transporter
EG219_RS04275	COG1131	(ABC) transporter
EG219_RS04280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EG219_RS04285	COG1278	Cold shock
EG219_RS04295	COG1464	Belongs to the NlpA lipoprotein family
EG219_RS04300	COG3706	GGDEF domain
EG219_RS04305	COG1823	symporter activity
EG219_RS04325	COG5577	PFAM Coat F domain
EG219_RS04330	COG0737	Belongs to the 5'-nucleotidase family
EG219_RS04330	COG1525	nuclease
EG219_RS04330	COG4085	toxin activity
EG219_RS04335	COG3764	Sortase (surface protein transpeptidase)
EG219_RS04340	COG0564	pseudouridine synthase activity
EG219_RS04350	COG0517	IMP dehydrogenase activity
EG219_RS04355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EG219_RS04360	COG3153	acetyltransferase
EG219_RS04360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EG219_RS04365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EG219_RS04370	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EG219_RS04375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EG219_RS04385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EG219_RS04390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EG219_RS04405	COG0431	NADPH-dependent FMN reductase
EG219_RS04420	COG1388	LysM domain
EG219_RS04420	COG0791	NLP P60 protein
EG219_RS04425	COG1959	2 iron, 2 sulfur cluster binding
EG219_RS04430	COG0668	transmembrane transport
EG219_RS04435	COG2719	SpoVR family
EG219_RS04440	COG1785	Belongs to the alkaline phosphatase family
EG219_RS04445	COG1388	LysM domain
EG219_RS04445	COG0791	NLP P60 protein
EG219_RS04450	COG0583	DNA-binding transcription factor activity
EG219_RS04455	COG0372	Belongs to the citrate synthase family
EG219_RS04460	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS04465	COG0531	amino acid
EG219_RS04470	COG0733	neurotransmitter:sodium symporter activity
EG219_RS04485	COG1595	DNA-templated transcription, initiation
EG219_RS04490	COG0204	Acyl-transferase
EG219_RS04495	COG1253	flavin adenine dinucleotide binding
EG219_RS04500	COG0789	Transcriptional regulator
EG219_RS04505	COG0436	Aminotransferase
EG219_RS04510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EG219_RS04515	COG1253	flavin adenine dinucleotide binding
EG219_RS04520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EG219_RS04525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EG219_RS04530	COG0584	glycerophosphoryl diester phosphodiesterase
EG219_RS04540	COG0668	transmembrane transport
EG219_RS04545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EG219_RS04550	COG0726	polysaccharide deacetylase
EG219_RS04555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EG219_RS04560	COG3226	Transcriptional regulator
EG219_RS04570	COG0589	response to stress
EG219_RS04575	COG1132	(ABC) transporter
EG219_RS04580	COG1132	(ABC) transporter
EG219_RS04585	COG0702	epimerase
EG219_RS04605	COG0189	ligase activity
EG219_RS04610	COG0189	ligase activity
EG219_RS04625	COG4335	DNA alkylation repair
EG219_RS04630	COG0561	phosphatase activity
EG219_RS04635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EG219_RS04645	COG0475	glutathione-regulated potassium exporter activity
EG219_RS04650	COG0490	domain, Protein
EG219_RS04660	COG1024	Enoyl-CoA hydratase
EG219_RS04670	COG4152	abc transporter atp-binding protein
EG219_RS04675	COG1668	transmembrane transport
EG219_RS04680	COG0420	3'-5' exonuclease activity
EG219_RS04685	COG4717	serine-type aminopeptidase activity
EG219_RS04700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EG219_RS04745	COG4980	gas vesicle protein
EG219_RS04760	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EG219_RS04765	COG0537	adenosine 5'-monophosphoramidase activity
EG219_RS04770	COG1131	(ABC) transporter
EG219_RS04775	COG4473	ABC transporter
EG219_RS04785	COG1473	amidohydrolase
EG219_RS04790	COG3069	C4-dicarboxylate transmembrane transporter activity
EG219_RS04795	COG2329	Antibiotic biosynthesis monooxygenase
EG219_RS04800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EG219_RS04810	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EG219_RS04815	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EG219_RS04820	COG1309	transcriptional regulator
EG219_RS04825	COG1511	domain protein
EG219_RS04830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EG219_RS04840	COG1363	Peptidase, m42
EG219_RS04845	COG1301	dicarboxylic acid transport
EG219_RS04855	COG1234	tRNA 3'-trailer cleavage
EG219_RS04860	COG0095	Lipoate-protein ligase
EG219_RS04865	COG0702	epimerase
EG219_RS04870	COG0318	PFAM AMP-dependent synthetase and ligase
EG219_RS04880	COG0501	Belongs to the peptidase M48B family
EG219_RS04885	COG1404	Belongs to the peptidase S8 family
EG219_RS04895	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EG219_RS04900	COG0406	alpha-ribazole phosphatase activity
EG219_RS04905	COG0183	Belongs to the thiolase family
EG219_RS04910	COG0318	PFAM AMP-dependent synthetase and ligase
EG219_RS04915	COG1268	BioY protein
EG219_RS04920	COG0840	transmembrane signaling receptor activity
EG219_RS04925	COG0723	plastoquinol--plastocyanin reductase activity
EG219_RS04925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EG219_RS04930	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS04940	COG4903	ComK protein
EG219_RS04950	COG5646	InterPro IPR014922
EG219_RS04970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EG219_RS04985	COG0398	Pfam SNARE associated Golgi protein
EG219_RS04990	COG0681	Belongs to the peptidase S26 family
EG219_RS04995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EG219_RS05000	COG1846	Transcriptional regulator
EG219_RS05005	COG3180	Ammonia monooxygenase
EG219_RS05010	COG2814	Major facilitator Superfamily
EG219_RS05020	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EG219_RS05025	COG2323	membrane
EG219_RS05040	COG0420	3'-5' exonuclease activity
EG219_RS05045	COG0419	ATPase involved in DNA repair
EG219_RS05050	COG1403	HNH endonuclease
EG219_RS05090	COG0179	Fumarylacetoacetate (FAA) hydrolase
EG219_RS05110	COG0367	asparagine synthase
EG219_RS05115	COG1562	ergosterol biosynthetic process
EG219_RS05120	COG0534	Mate efflux family protein
EG219_RS05125	COG1917	Cupin 2, conserved barrel domain protein
EG219_RS05125	COG2207	Transcriptional regulator
EG219_RS05130	COG2318	DinB family
EG219_RS05140	COG1357	PFAM Pentapeptide repeats (8 copies)
EG219_RS05145	COG2153	protein acetylation
EG219_RS05150	COG0646	methionine synthase
EG219_RS05150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EG219_RS05160	COG2996	Protein conserved in bacteria
EG219_RS05165	COG1744	ABC transporter substrate-binding protein PnrA-like
EG219_RS05170	COG0840	transmembrane signaling receptor activity
EG219_RS05180	COG1307	EDD domain protein, DegV family
EG219_RS05185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EG219_RS05200	COG0561	phosphatase activity
EG219_RS05205	COG1073	alpha beta
EG219_RS05210	COG2151	metal-sulfur cluster biosynthetic enzyme
EG219_RS05220	COG0277	FAD linked oxidase domain protein
EG219_RS05225	COG2271	Major facilitator Superfamily
EG219_RS05235	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EG219_RS05245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EG219_RS05250	COG0505	Belongs to the CarA family
EG219_RS05255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EG219_RS05260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EG219_RS05280	COG2267	carboxylic ester hydrolase activity
EG219_RS05290	COG1744	ABC transporter substrate-binding protein PnrA-like
EG219_RS05305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EG219_RS05310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EG219_RS05315	COG5504	Zn-dependent protease
EG219_RS05320	COG0444	Belongs to the ABC transporter superfamily
EG219_RS05325	COG4608	Belongs to the ABC transporter superfamily
EG219_RS05335	COG0601	transmembrane transport
EG219_RS05340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EG219_RS05350	COG0180	Tryptophanyl-tRNA synthetase
EG219_RS05355	COG4166	transmembrane transport
EG219_RS05360	COG0601	transmembrane transport
EG219_RS05365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EG219_RS05370	COG0444	Belongs to the ABC transporter superfamily
EG219_RS05375	COG4608	Belongs to the ABC transporter superfamily
EG219_RS05385	COG0456	acetyltransferase
EG219_RS05390	COG1393	Belongs to the ArsC family
EG219_RS05395	COG0861	Integral membrane protein TerC family
EG219_RS05400	COG4862	establishment of competence for transformation
EG219_RS05405	COG4469	Competence protein
EG219_RS05410	COG1164	Oligoendopeptidase f
EG219_RS05415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EG219_RS05420	COG2346	COG2346, Truncated hemoglobins
EG219_RS05425	COG0741	lytic transglycosylase activity
EG219_RS05430	COG4116	CYTH
EG219_RS05440	COG2357	RelA SpoT domain protein
EG219_RS05445	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EG219_RS05450	COG0564	pseudouridine synthase activity
EG219_RS05465	COG0475	glutathione-regulated potassium exporter activity
EG219_RS05465	COG0569	domain protein
EG219_RS05470	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EG219_RS05475	COG0352	thiamine-phosphate diphosphorylase activity
EG219_RS05480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EG219_RS05485	COG2104	thiamine diphosphate biosynthetic process
EG219_RS05495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EG219_RS05500	COG0351	phosphomethylpyrimidine kinase
EG219_RS05505	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EG219_RS05560	COG0210	DNA helicase
EG219_RS05580	COG1131	(ABC) transporter
EG219_RS05590	COG2153	protein acetylation
EG219_RS05600	COG2382	esterase
EG219_RS05605	COG0626	cystathionine gamma-synthase activity
EG219_RS05610	COG0626	cystathionine gamma-synthase activity
EG219_RS05630	COG0346	lactoylglutathione lyase activity
EG219_RS05635	COG2367	Beta-lactamase
EG219_RS05640	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EG219_RS05650	COG1846	Transcriptional regulator
EG219_RS05660	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EG219_RS05665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EG219_RS05670	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EG219_RS05675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EG219_RS05675	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EG219_RS05680	COG1447	Phosphotransferase system cellobiose-specific component IIA
EG219_RS05715	COG1285	pathogenesis
EG219_RS05730	COG2205	protein histidine kinase activity
EG219_RS05740	COG3383	formate dehydrogenase (NAD+) activity
EG219_RS05745	COG2427	Protein of unknown function (DUF1641)
EG219_RS05750	COG2124	cytochrome p450
EG219_RS05755	COG1819	glycosyl
EG219_RS05765	COG1587	Uroporphyrinogen-III synthase
EG219_RS05770	COG0390	transport system, permease component
EG219_RS05775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EG219_RS05780	COG0697	spore germination
EG219_RS05785	COG4297	protein containing double-stranded beta helix domain
EG219_RS05795	COG1252	NADH dehydrogenase
EG219_RS05805	COG2211	Major facilitator Superfamily
EG219_RS05810	COG1609	Transcriptional regulator
EG219_RS05815	COG0246	Mannitol dehydrogenase
EG219_RS05820	COG2721	sulfolactate sulfo-lyase activity
EG219_RS05825	COG0730	response to heat
EG219_RS05830	COG2318	DinB family
EG219_RS05835	COG0457	Tetratricopeptide repeat
EG219_RS05840	COG3409	Peptidoglycan-binding domain 1 protein
EG219_RS05840	COG5632	N-Acetylmuramoyl-L-alanine amidase
EG219_RS05840	COG1388	LysM domain
EG219_RS05850	COG4195	phage-related replication protein
EG219_RS05855	COG2856	Zn peptidase
EG219_RS05860	COG1396	sequence-specific DNA binding
EG219_RS05870	COG1522	sequence-specific DNA binding
EG219_RS05875	COG1484	DNA-dependent DNA replication
EG219_RS05890	COG1595	DNA-templated transcription, initiation
EG219_RS05895	COG3728	DNA packaging
EG219_RS05895	COG5484	DNA packaging
EG219_RS05900	COG1783	phage Terminase large subunit
EG219_RS05905	COG5518	Phage portal protein
EG219_RS05910	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EG219_RS05915	COG4653	Phage capsid family
EG219_RS05970	COG1652	LysM domain
EG219_RS05975	COG4193	domain, Protein
EG219_RS05985	COG3628	GPW Gp25 family protein
EG219_RS05990	COG3299	homolog of phage Mu protein gp47
EG219_RS05995	COG3778	Protein conserved in bacteria
EG219_RS06035	COG3409	Peptidoglycan-binding domain 1 protein
EG219_RS06035	COG5632	N-Acetylmuramoyl-L-alanine amidase
EG219_RS06050	COG0306	phosphate transporter
EG219_RS06055	COG1392	Phosphate transport regulator
EG219_RS06060	COG0531	amino acid
EG219_RS06065	COG0346	lactoylglutathione lyase activity
EG219_RS06070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EG219_RS06075	COG0463	Glycosyl transferase, family 2
EG219_RS06080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EG219_RS06085	COG0477	Major facilitator Superfamily
EG219_RS06090	COG2362	D-Aminopeptidase
EG219_RS06095	COG0601	transmembrane transport
EG219_RS06100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EG219_RS06105	COG0444	Belongs to the ABC transporter superfamily
EG219_RS06110	COG4166	transmembrane transport
EG219_RS06115	COG1619	proteins homologs of microcin C7 resistance protein MccF
EG219_RS06120	COG4948	Mandelate Racemase Muconate Lactonizing
EG219_RS06125	COG0791	NLP P60 protein
EG219_RS06130	COG4608	Belongs to the ABC transporter superfamily
EG219_RS06135	COG2706	6-phosphogluconolactonase activity
EG219_RS06140	COG1834	amidinotransferase
EG219_RS06145	COG1607	acyl-coa hydrolase
EG219_RS06150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EG219_RS06155	COG2076	Multidrug Resistance protein
EG219_RS06160	COG2076	Multidrug Resistance protein
EG219_RS06165	COG0788	formyltetrahydrofolate deformylase activity
EG219_RS06170	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EG219_RS06180	COG1764	response to oxidative stress
EG219_RS06185	COG1846	Transcriptional regulator
EG219_RS06190	COG1764	response to oxidative stress
EG219_RS06205	COG0457	Tetratricopeptide repeat
EG219_RS06205	COG0463	Glycosyl transferase, family 2
EG219_RS06215	COG2814	Major facilitator Superfamily
EG219_RS06220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EG219_RS06230	COG1404	Belongs to the peptidase S8 family
EG219_RS06235	COG1366	Belongs to the anti-sigma-factor antagonist family
EG219_RS06240	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EG219_RS06245	COG1122	ATPase activity
EG219_RS06250	COG4721	ABC-type cobalt transport system, permease component
EG219_RS06255	COG3858	chitin binding
EG219_RS06255	COG1388	LysM domain
EG219_RS06275	COG2239	Acts as a magnesium transporter
EG219_RS06280	COG0789	Transcriptional regulator
EG219_RS06295	COG1846	Transcriptional regulator
EG219_RS06300	COG0726	polysaccharide deacetylase
EG219_RS06305	COG1793	dna ligase
EG219_RS06305	COG3285	dna ligase
EG219_RS06310	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EG219_RS06315	COG0586	Pfam SNARE associated Golgi protein
EG219_RS06320	COG0861	Integral membrane protein TerC family
EG219_RS06325	COG1191	sigma factor activity
EG219_RS06350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EG219_RS06355	COG2323	membrane
EG219_RS06365	COG3594	Acyltransferase
EG219_RS06370	COG5002	protein histidine kinase activity
EG219_RS06375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EG219_RS06390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EG219_RS06395	COG0436	Aminotransferase
EG219_RS06425	COG3852	Histidine kinase
EG219_RS06430	COG1846	Transcriptional regulator
EG219_RS06435	COG1360	Flagellar Motor Protein
EG219_RS06440	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EG219_RS06445	COG0542	response to heat
EG219_RS06455	COG3949	Membrane
EG219_RS06470	COG0720	synthase
EG219_RS06475	COG0602	queuosine metabolic process
EG219_RS06490	COG4873	Protein conserved in bacteria
EG219_RS06500	COG3773	Cell wall hydrolase
EG219_RS06505	COG2244	polysaccharide biosynthetic process
EG219_RS06510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG219_RS06515	COG2217	Heavy metal translocating P-type atpase
EG219_RS06520	COG0006	proline dipeptidase activity
EG219_RS06525	COG1609	Transcriptional regulator
EG219_RS06530	COG3711	transcriptional antiterminator
EG219_RS06535	COG2190	(PTS) system
EG219_RS06535	COG1263	PTS System
EG219_RS06535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EG219_RS06540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EG219_RS06545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EG219_RS06555	COG1533	DNA photolyase activity
EG219_RS06560	COG0840	transmembrane signaling receptor activity
EG219_RS06565	COG2084	Dehydrogenase
EG219_RS06570	COG2340	Cysteine-rich secretory protein family
EG219_RS06575	COG0768	penicillin binding
EG219_RS06580	COG4191	Histidine kinase
EG219_RS06585	COG0436	Aminotransferase
EG219_RS06595	COG0784	Response regulator, receiver
EG219_RS06595	COG0835	chemotaxis
EG219_RS06605	COG2814	Major facilitator Superfamily
EG219_RS06610	COG1376	ErfK ybiS ycfS ynhG family protein
EG219_RS06615	COG1408	metallophosphoesterase
EG219_RS06620	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS06630	COG2200	EAL domain
EG219_RS06635	COG4703	Protein of unknown function (DUF1797)
EG219_RS06640	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EG219_RS06650	COG0517	IMP dehydrogenase activity
EG219_RS06655	COG0583	DNA-binding transcription factor activity
EG219_RS06660	COG0716	FMN binding
EG219_RS06670	COG0716	FMN binding
EG219_RS06690	COG0668	transmembrane transport
EG219_RS06695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG219_RS06715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EG219_RS06720	COG0303	'Molybdopterin
EG219_RS06725	COG1763	Mo-molybdopterin cofactor biosynthetic process
EG219_RS06730	COG0314	molybdopterin synthase activity
EG219_RS06735	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EG219_RS06745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EG219_RS06750	COG1136	(ABC) transporter
EG219_RS06755	COG0577	efflux transmembrane transporter activity
EG219_RS06760	COG1349	DNA-binding transcription factor activity
EG219_RS06765	COG1105	Belongs to the carbohydrate kinase PfkB family
EG219_RS06770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EG219_RS06770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EG219_RS06770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EG219_RS06775	COG0681	Belongs to the peptidase S26 family
EG219_RS06785	COG0488	(ABC) transporter
EG219_RS06790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EG219_RS06795	COG2309	aminopeptidase activity
EG219_RS06805	COG1077	Cell shape determining protein MreB Mrl
EG219_RS06815	COG2002	toxin-antitoxin pair type II binding
EG219_RS06820	COG3852	Histidine kinase
EG219_RS06825	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EG219_RS06825	COG2105	PFAM AIG2 family protein
EG219_RS06830	COG0569	domain protein
EG219_RS06840	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EG219_RS06850	COG0561	phosphatase activity
EG219_RS06855	COG0242	peptide deformylase activity
EG219_RS06865	COG0497	DNA recombination
EG219_RS06880	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS06880	COG4221	oxidoreductase activity
EG219_RS06880	COG3321	synthase
EG219_RS06880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS06885	COG0300	oxidoreductase activity
EG219_RS06885	COG4221	oxidoreductase activity
EG219_RS06885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG219_RS06885	COG3321	synthase
EG219_RS06890	COG3321	synthase
EG219_RS06890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS06890	COG4221	oxidoreductase activity
EG219_RS06890	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS06895	COG4221	oxidoreductase activity
EG219_RS06895	COG0300	oxidoreductase activity
EG219_RS06895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG219_RS06895	COG3321	synthase
EG219_RS06900	COG4221	oxidoreductase activity
EG219_RS06900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG219_RS06900	COG3321	synthase
EG219_RS06900	COG0300	oxidoreductase activity
EG219_RS06905	COG3321	synthase
EG219_RS06905	COG0300	oxidoreductase activity
EG219_RS06905	COG4221	oxidoreductase activity
EG219_RS06905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG219_RS06910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS06910	COG4221	oxidoreductase activity
EG219_RS06910	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS06910	COG3321	synthase
EG219_RS06915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EG219_RS06920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EG219_RS06925	COG0022	dehydrogenase e1 component
EG219_RS06930	COG0508	dehydrogenase complex catalyzes the overall conversion of
EG219_RS06935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EG219_RS06940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG219_RS06955	COG1982	Orn Lys Arg decarboxylase major
EG219_RS06980	COG0483	inositol monophosphate 1-phosphatase activity
EG219_RS06990	COG3227	Zinc metalloprotease (Elastase)
EG219_RS07015	COG1217	gtp-binding protein TYPA
EG219_RS07025	COG4896	Protein conserved in bacteria
EG219_RS07035	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EG219_RS07040	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EG219_RS07045	COG2066	Belongs to the glutaminase family
EG219_RS07055	COG0772	Belongs to the SEDS family
EG219_RS07060	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EG219_RS07075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EG219_RS07075	COG2010	Cytochrome c
EG219_RS07080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EG219_RS07085	COG1845	cytochrome c oxidase, subunit III
EG219_RS07090	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EG219_RS07095	COG3336	cytochrome c oxidase
EG219_RS07105	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EG219_RS07110	COG2340	Cysteine-rich secretory protein family
EG219_RS07125	COG3679	Belongs to the UPF0342 family
EG219_RS07140	COG0742	ribosomal rna small subunit methyltransferase
EG219_RS07150	COG3314	Sporulation integral membrane protein YlbJ
EG219_RS07155	COG1752	Esterase of the alpha-beta hydrolase superfamily
EG219_RS07160	COG3480	Lon protease (S16) C-terminal proteolytic domain
EG219_RS07170	COG1399	metal-binding, possibly nucleic acid-binding protein
EG219_RS07190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EG219_RS07210	COG4839	cell division protein FtsL
EG219_RS07215	COG0768	penicillin binding
EG219_RS07220	COG0768	penicillin binding
EG219_RS07240	COG0772	Belongs to the SEDS family
EG219_RS07255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EG219_RS07260	COG0849	cell division
EG219_RS07265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EG219_RS07270	COG1404	Belongs to the peptidase S8 family
EG219_RS07270	COG4412	M6 family metalloprotease domain protein
EG219_RS07280	COG1191	sigma factor activity
EG219_RS07285	COG1191	sigma factor activity
EG219_RS07290	COG1119	ATPase activity
EG219_RS07295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EG219_RS07300	COG1873	PFAM PRC-barrel domain
EG219_RS07305	COG1496	oxidoreductase activity
EG219_RS07310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EG219_RS07320	COG0762	integral membrane protein
EG219_RS07325	COG2302	S4 RNA-binding domain
EG219_RS07330	COG3599	regulation of cell shape
EG219_RS07340	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EG219_RS07345	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EG219_RS07355	COG0564	pseudouridine synthase activity
EG219_RS07365	COG2233	PERMEase
EG219_RS07375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EG219_RS07380	COG0505	Belongs to the CarA family
EG219_RS07385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EG219_RS07400	COG0284	orotidine-5'-phosphate decarboxylase activity
EG219_RS07405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EG219_RS07415	COG0306	phosphate transporter
EG219_RS07430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EG219_RS07435	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
EG219_RS07440	COG1648	precorrin-2 dehydrogenase activity
EG219_RS07455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EG219_RS07460	COG1561	YicC-like family, N-terminal region
EG219_RS07470	COG0194	GDP metabolic process
EG219_RS07480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EG219_RS07485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EG219_RS07490	COG0242	peptide deformylase activity
EG219_RS07500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EG219_RS07500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EG219_RS07510	COG0631	protein serine/threonine phosphatase activity
EG219_RS07515	COG0515	serine threonine protein kinase
EG219_RS07515	COG2815	serine threonine protein kinase
EG219_RS07525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EG219_RS07530	COG1564	THIamine pyrophosphokinase
EG219_RS07545	COG1302	Protein conserved in bacteria
EG219_RS07550	COG1461	Dihydroxyacetone kinase
EG219_RS07555	COG1760	l-serine dehydratase
EG219_RS07560	COG1760	l-serine dehydratase
EG219_RS07565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EG219_RS07580	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EG219_RS07585	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS07600	COG1196	nuclear chromosome segregation
EG219_RS07605	COG0552	protein localization to endoplasmic reticulum
EG219_RS07620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EG219_RS07630	COG1837	Belongs to the UPF0109 family
EG219_RS07655	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EG219_RS07670	COG2257	FlhB HrpN YscU SpaS Family
EG219_RS07680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EG219_RS07685	COG0758	DNA mediated transformation
EG219_RS07690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EG219_RS07700	COG4974	Belongs to the 'phage' integrase family
EG219_RS07720	COG1815	bacterial-type flagellum-dependent cell motility
EG219_RS07725	COG1558	bacterial-type flagellum-dependent cell motility
EG219_RS07730	COG1677	Flagellar hook-basal body complex protein FliE
EG219_RS07735	COG1766	The M ring may be actively involved in energy transduction
EG219_RS07740	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EG219_RS07745	COG1317	bacterial-type flagellum organization
EG219_RS07750	COG1157	protein secretion by the type III secretion system
EG219_RS07755	COG2882	bacterial-type flagellum organization
EG219_RS07760	COG3334	PFAM MgtE intracellular
EG219_RS07765	COG3144	bacterial-type flagellum assembly
EG219_RS07770	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EG219_RS07775	COG4786	Flagellar basal body rod
EG219_RS07780	COG1582	Flagellar protein (FlbD)
EG219_RS07785	COG1580	Controls the rotational direction of flagella during chemotaxis
EG219_RS07790	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EG219_RS07795	COG1776	CheC inhibitor of MCP methylation
EG219_RS07795	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EG219_RS07800	COG2201	protein-glutamate methylesterase activity
EG219_RS07805	COG3190	flagellar
EG219_RS07810	COG1338	Plays a role in the flagellum-specific transport system
EG219_RS07815	COG1987	bacterial-type flagellum assembly
EG219_RS07820	COG1684	flagellar biosynthetic protein fliR
EG219_RS07825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EG219_RS07830	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EG219_RS07835	COG1419	protein localization to endoplasmic reticulum
EG219_RS07840	COG0455	bacterial-type flagellum organization
EG219_RS07845	COG2201	protein-glutamate methylesterase activity
EG219_RS07850	COG0643	Histidine kinase
EG219_RS07850	COG2198	Histidine kinase
EG219_RS07855	COG0835	chemotaxis
EG219_RS07860	COG1776	CheC inhibitor of MCP methylation
EG219_RS07870	COG1191	sigma factor activity
EG219_RS07900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EG219_RS07905	COG4589	Belongs to the CDS family
EG219_RS07915	COG0750	zinc metalloprotease
EG219_RS07925	COG2176	DNA-directed DNA polymerase activity
EG219_RS07935	COG0195	Participates in both transcription termination and antitermination
EG219_RS07940	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EG219_RS07945	COG1358	cellular component organization or biogenesis
EG219_RS07955	COG1550	Protein conserved in bacteria
EG219_RS07970	COG0196	riboflavin kinase activity
EG219_RS07985	COG0726	polysaccharide deacetylase
EG219_RS07990	COG0612	Peptidase, M16
EG219_RS07995	COG1873	PFAM PRC-barrel domain
EG219_RS08000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EG219_RS08005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EG219_RS08010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EG219_RS08015	COG0527	aspartate kinase activity
EG219_RS08025	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EG219_RS08030	COG0740	serine-type endopeptidase activity
EG219_RS08040	COG4980	gas vesicle protein
EG219_RS08040	COG1674	ftsk spoiiie
EG219_RS08045	COG2188	Transcriptional regulator
EG219_RS08050	COG2814	Major facilitator Superfamily
EG219_RS08055	COG1846	Transcriptional regulator
EG219_RS08060	COG2409	Drug exporters of the RND superfamily
EG219_RS08060	COG1033	growth of symbiont in host cell
EG219_RS08065	COG0612	Peptidase, M16
EG219_RS08070	COG0612	Peptidase, M16
EG219_RS08075	COG0300	oxidoreductase activity
EG219_RS08090	COG1426	Protein conserved in bacteria
EG219_RS08095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EG219_RS08110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EG219_RS08120	COG1692	metallophosphoesterase
EG219_RS08125	COG2359	stage V sporulation protein S
EG219_RS08145	COG4550	Control of competence regulator ComK, YlbF/YmcA
EG219_RS08200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG219_RS08205	COG3425	synthase
EG219_RS08210	COG1024	Enoyl-CoA hydratase
EG219_RS08215	COG1024	Enoyl-CoA hydratase
EG219_RS08220	COG3321	synthase
EG219_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS08220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS08220	COG0318	PFAM AMP-dependent synthetase and ligase
EG219_RS08220	COG0300	oxidoreductase activity
EG219_RS08225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG219_RS08225	COG0300	oxidoreductase activity
EG219_RS08225	COG4221	oxidoreductase activity
EG219_RS08225	COG3321	synthase
EG219_RS08230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EG219_RS08230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG219_RS08230	COG3321	synthase
EG219_RS08230	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS08230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS08230	COG3321	synthase
EG219_RS08230	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS08230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS08230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EG219_RS08230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG219_RS08235	COG4221	oxidoreductase activity
EG219_RS08235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS08235	COG3321	synthase
EG219_RS08235	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS08240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG219_RS08240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EG219_RS08240	COG3321	synthase
EG219_RS08240	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EG219_RS08245	COG2124	cytochrome p450
EG219_RS08250	COG3209	COG3209 Rhs family protein
EG219_RS08255	COG3619	membrane
EG219_RS08265	COG1404	Belongs to the peptidase S8 family
EG219_RS08275	COG4195	phage-related replication protein
EG219_RS08280	COG1764	response to oxidative stress
EG219_RS08290	COG2076	Multidrug Resistance protein
EG219_RS08330	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EG219_RS08335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EG219_RS08340	COG4112	unkown
EG219_RS08345	COG0860	N-Acetylmuramoyl-L-alanine amidase
EG219_RS08355	COG0464	growth
EG219_RS08360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EG219_RS08365	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EG219_RS08370	COG0789	Transcriptional regulator
EG219_RS08375	COG0174	glutamine synthetase
EG219_RS08385	COG2211	Major facilitator Superfamily
EG219_RS08390	COG3507	Belongs to the glycosyl hydrolase 43 family
EG219_RS08405	COG1070	Carbohydrate kinase
EG219_RS08410	COG3848	Pyruvate phosphate dikinase
EG219_RS08410	COG0574	Belongs to the PEP-utilizing enzyme family
EG219_RS08435	COG1064	alcohol dehydrogenase
EG219_RS08450	COG0456	acetyltransferase
EG219_RS08470	COG3397	chitin binding
EG219_RS08490	COG5434	Belongs to the glycosyl hydrolase 28 family
EG219_RS08495	COG0756	dUTP diphosphatase activity
EG219_RS08505	COG4195	phage-related replication protein
EG219_RS08535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EG219_RS08545	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EG219_RS08565	COG0785	Cytochrome C biogenesis protein
EG219_RS08570	COG2201	protein-glutamate methylesterase activity
EG219_RS08575	COG4846	Membrane protein involved in cytochrome C biogenesis
EG219_RS08585	COG0071	Belongs to the small heat shock protein (HSP20) family
EG219_RS08600	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EG219_RS08605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG219_RS08625	COG0824	Thioesterase
EG219_RS08635	COG4841	protein insertion into membrane
EG219_RS08645	COG1832	CoA-binding protein
EG219_RS08650	COG0187	DNA topoisomerase II activity
EG219_RS08655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EG219_RS08665	COG1115	amino acid carrier protein
EG219_RS08675	COG1063	alcohol dehydrogenase
EG219_RS08680	COG0800	Aldolase
EG219_RS08685	COG1312	Catalyzes the dehydration of D-mannonate
EG219_RS08690	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS08695	COG1609	Transcriptional regulator
EG219_RS08700	COG2271	Major facilitator Superfamily
EG219_RS08735	COG2205	protein histidine kinase activity
EG219_RS08740	COG0745	RESPONSE REGULATOR receiver
EG219_RS08750	COG3507	Belongs to the glycosyl hydrolase 43 family
EG219_RS08775	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS08780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EG219_RS08785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EG219_RS08790	COG2610	gluconate transmembrane transporter activity
EG219_RS08795	COG2124	cytochrome p450
EG219_RS08815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EG219_RS08825	COG2246	polysaccharide biosynthetic process
EG219_RS08830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EG219_RS08835	COG0586	Pfam SNARE associated Golgi protein
EG219_RS08840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EG219_RS08845	COG1024	Enoyl-CoA hydratase
EG219_RS08850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EG219_RS08855	COG0511	ligase activity, forming carbon-carbon bonds
EG219_RS08860	COG0439	Biotin carboxylase
EG219_RS08865	COG0318	PFAM AMP-dependent synthetase and ligase
EG219_RS08870	COG1960	acyl-CoA dehydrogenase activity
EG219_RS08875	COG1649	PFAM Uncharacterised BCR, COG1649
EG219_RS08885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS08885	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EG219_RS08900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS08915	COG2027	D-alanyl-D-alanine carboxypeptidase
EG219_RS08920	COG2017	converts alpha-aldose to the beta-anomer
EG219_RS08925	COG0534	Mate efflux family protein
EG219_RS08940	COG0582	viral genome integration into host DNA
EG219_RS08945	COG0166	Belongs to the GPI family
EG219_RS08950	COG0405	Gamma-glutamyltransferase
EG219_RS08955	COG2814	Major facilitator Superfamily
EG219_RS08960	COG0640	Transcriptional regulator
EG219_RS08965	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EG219_RS08975	COG0604	alcohol dehydrogenase
EG219_RS08980	COG0493	'glutamate synthase
EG219_RS08985	COG0069	glutamate synthase activity
EG219_RS08985	COG0070	glutamate synthase
EG219_RS08985	COG0067	glutamate synthase
EG219_RS08990	COG0583	DNA-binding transcription factor activity
EG219_RS08995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EG219_RS09010	COG0300	oxidoreductase activity
EG219_RS09015	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EG219_RS09025	COG2814	Major facilitator Superfamily
EG219_RS09030	COG1070	Carbohydrate kinase
EG219_RS09035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EG219_RS09040	COG0243	molybdopterin cofactor binding
EG219_RS09070	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS09075	COG1733	regulation of RNA biosynthetic process
EG219_RS09080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG219_RS09085	COG0662	Cupin 2, conserved barrel domain protein
EG219_RS09085	COG2207	Transcriptional regulator
EG219_RS09090	COG1309	transcriptional regulator
EG219_RS09095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG219_RS09105	COG0640	Transcriptional regulator
EG219_RS09110	COG0741	lytic transglycosylase activity
EG219_RS09115	COG2322	membrane
EG219_RS09130	COG1619	proteins homologs of microcin C7 resistance protein MccF
EG219_RS09140	COG1388	LysM domain
EG219_RS09140	COG3584	3D domain protein
EG219_RS09145	COG0514	ATP-dependent DNA helicase (RecQ)
EG219_RS09155	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EG219_RS09160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EG219_RS09175	COG0071	Belongs to the small heat shock protein (HSP20) family
EG219_RS09205	COG1012	belongs to the aldehyde dehydrogenase family
EG219_RS09210	COG1657	PFAM Prenyltransferase squalene oxidase
EG219_RS09215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EG219_RS09220	COG0733	neurotransmitter:sodium symporter activity
EG219_RS09225	COG0385	Bile acid
EG219_RS09230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG219_RS09235	COG0508	dehydrogenase complex catalyzes the overall conversion of
EG219_RS09245	COG4548	von Willebrand factor, type A
EG219_RS09250	COG0714	Associated with various cellular activities
EG219_RS09255	COG2032	superoxide dismutase activity
EG219_RS09260	COG1388	LysM domain
EG219_RS09260	COG0791	NLP P60 protein
EG219_RS09265	COG1819	glycosyl
EG219_RS09270	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EG219_RS09275	COG0534	Mate efflux family protein
EG219_RS09280	COG1366	Belongs to the anti-sigma-factor antagonist family
EG219_RS09285	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EG219_RS09290	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EG219_RS09300	COG2962	Rard protein
EG219_RS09315	COG1942	4-Oxalocrotonate Tautomerase
EG219_RS09325	COG1733	regulation of RNA biosynthetic process
EG219_RS09330	COG0778	Nitroreductase
EG219_RS09335	COG0400	carboxylic ester hydrolase activity
EG219_RS09340	COG0346	lactoylglutathione lyase activity
EG219_RS09350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EG219_RS09360	COG2723	6-phospho-beta-galactosidase activity
EG219_RS09365	COG2188	Transcriptional regulator
EG219_RS09370	COG0793	Belongs to the peptidase S41A family
EG219_RS09370	COG3409	Peptidoglycan-binding domain 1 protein
EG219_RS09375	COG2226	methyltransferase
EG219_RS09385	COG1876	peptidase activity
EG219_RS09405	COG0671	phosphoesterase, PA-phosphatase related
EG219_RS09435	COG1509	lysine 2,3-aminomutase activity
EG219_RS09440	COG0456	acetyltransferase
EG219_RS09445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EG219_RS09450	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EG219_RS09455	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EG219_RS09460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EG219_RS09475	COG0456	acetyltransferase
EG219_RS09480	COG0463	Glycosyl transferase, family 2
EG219_RS09495	COG4641	Protein conserved in bacteria
EG219_RS09505	COG1086	Polysaccharide biosynthesis protein
EG219_RS09520	COG1846	Transcriptional regulator
EG219_RS09525	COG4698	Protein conserved in bacteria
EG219_RS09530	COG2755	lipolytic protein G-D-S-L family
EG219_RS09535	COG1999	signal sequence binding
EG219_RS09545	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EG219_RS09550	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EG219_RS09555	COG1272	protein, Hemolysin III
EG219_RS09560	COG0204	Acyl-transferase
EG219_RS09565	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EG219_RS09580	COG2136	Putative SAM-dependent methyltransferase
EG219_RS09580	COG2521	methyltransferase
EG219_RS09595	COG1413	lyase activity
EG219_RS09600	COG1418	mRNA catabolic process
EG219_RS09605	COG0386	Belongs to the glutathione peroxidase family
EG219_RS09615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EG219_RS09625	COG1278	Cold shock
EG219_RS09645	COG0328	RNA-DNA hybrid ribonuclease activity
EG219_RS09650	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EG219_RS09655	COG0328	RNA-DNA hybrid ribonuclease activity
EG219_RS09665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EG219_RS09680	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EG219_RS09690	COG1755	Isoprenylcysteine carboxyl methyltransferase
EG219_RS09695	COG3424	synthase
EG219_RS09710	COG2323	membrane
EG219_RS09715	COG1335	isochorismatase
EG219_RS09735	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EG219_RS09740	COG1199	ATP-dependent helicase activity
EG219_RS09755	COG0116	Belongs to the methyltransferase superfamily
EG219_RS09785	COG3359	exonuclease
EG219_RS09790	COG1111	helicase
EG219_RS09790	COG1205	dead DEAH box helicase
EG219_RS09795	COG2190	(PTS) system
EG219_RS09800	COG0071	Belongs to the small heat shock protein (HSP20) family
EG219_RS09840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EG219_RS09840	COG4499	WXG100 protein secretion system (Wss), protein YukC
EG219_RS09850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EG219_RS09855	COG3935	DnaD domain protein
EG219_RS09865	COG0436	Aminotransferase
EG219_RS09870	COG5353	protein conserved in bacteria
EG219_RS09880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EG219_RS09880	COG1199	ATP-dependent helicase activity
EG219_RS09910	COG0438	transferase activity, transferring glycosyl groups
EG219_RS09915	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EG219_RS09930	COG1694	Mazg nucleotide pyrophosphohydrolase
EG219_RS09935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EG219_RS09940	COG2140	Oxalate decarboxylase
EG219_RS09950	COG4347	Protein of unknown function (DUF1405)
EG219_RS09955	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EG219_RS09955	COG2010	Cytochrome c
EG219_RS09960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EG219_RS09965	COG0723	plastoquinol--plastocyanin reductase activity
EG219_RS09980	COG0457	Tetratricopeptide repeat
EG219_RS09990	COG0287	Prephenate dehydrogenase
EG219_RS10025	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EG219_RS10030	COG4401	Chorismate mutase type I
EG219_RS10045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EG219_RS10050	COG0105	UTP biosynthetic process
EG219_RS10055	COG0142	geranyltranstransferase activity
EG219_RS10065	COG0142	geranyltranstransferase activity
EG219_RS10080	COG0776	regulation of translation
EG219_RS10085	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EG219_RS10125	COG0539	negative regulation of cytoplasmic translation
EG219_RS10135	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EG219_RS10140	COG2959	enzyme of heme biosynthesis
EG219_RS10145	COG3773	Cell wall hydrolase
EG219_RS10145	COG3409	Peptidoglycan-binding domain 1 protein
EG219_RS10150	COG2339	peptidase activity
EG219_RS10155	COG0492	ferredoxin-NADP+ reductase activity
EG219_RS10160	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EG219_RS10165	COG4862	establishment of competence for transformation
EG219_RS10170	COG1408	metallophosphoesterase
EG219_RS10180	COG1388	LysM domain
EG219_RS10185	COG1266	CAAX protease self-immunity
EG219_RS10190	COG0514	ATP-dependent DNA helicase (RecQ)
EG219_RS10195	COG4955	Helix-turn-helix domain
EG219_RS10200	COG1141	Ferredoxin
EG219_RS10205	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EG219_RS10210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EG219_RS10220	COG1595	DNA-templated transcription, initiation
EG219_RS10225	COG5002	protein histidine kinase activity
EG219_RS10230	COG0745	RESPONSE REGULATOR receiver
EG219_RS10235	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EG219_RS10240	COG1333	cytochrome c biogenesis protein
EG219_RS10245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG219_RS10250	COG1187	pseudouridine synthase activity
EG219_RS10255	COG0700	Nucleoside recognition
EG219_RS10260	COG2715	membrane protein required for spore maturation
EG219_RS10265	COG1686	Belongs to the peptidase S11 family
EG219_RS10290	COG1547	Domain of unknown function (DUF309)
EG219_RS10300	COG0456	acetyltransferase
EG219_RS10315	COG0307	riboflavin synthase, alpha
EG219_RS10320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EG219_RS10320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EG219_RS10330	COG0681	Belongs to the peptidase S26 family
EG219_RS10340	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EG219_RS10345	COG4086	secreted protein
EG219_RS10350	COG0019	diaminopimelate decarboxylase activity
EG219_RS10355	COG0697	spore germination
EG219_RS10370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EG219_RS10390	COG1191	sigma factor activity
EG219_RS10400	COG1366	Belongs to the anti-sigma-factor antagonist family
EG219_RS10405	COG1686	Belongs to the peptidase S11 family
EG219_RS10410	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EG219_RS10415	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EG219_RS10420	COG4974	Belongs to the 'phage' integrase family
EG219_RS10430	COG0735	belongs to the Fur family
EG219_RS10435	COG1300	Membrane
EG219_RS10450	COG0281	malic enzyme
EG219_RS10455	COG1757	Na H antiporter
EG219_RS10460	COG1027	Aspartate ammonia-lyase
EG219_RS10465	COG0252	asparaginase activity
EG219_RS10470	COG1396	sequence-specific DNA binding
EG219_RS10475	COG1379	DNA repair
EG219_RS10480	COG0494	nUDIX hydrolase
EG219_RS10490	COG0667	Aldo Keto reductase
EG219_RS10500	COG1073	alpha beta
EG219_RS10510	COG4918	Iron-sulphur cluster biosynthesis
EG219_RS10515	COG0456	acetyltransferase
EG219_RS10515	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EG219_RS10520	COG2329	Antibiotic biosynthesis monooxygenase
EG219_RS10525	COG0456	acetyltransferase
EG219_RS10530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EG219_RS10545	COG0628	permease
EG219_RS10555	COG0346	lactoylglutathione lyase activity
EG219_RS10565	COG3048	D-serine ammonia-lyase activity
EG219_RS10570	COG0300	oxidoreductase activity
EG219_RS10575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG219_RS10580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EG219_RS10585	COG1024	Enoyl-CoA hydratase
EG219_RS10590	COG3425	synthase
EG219_RS10595	COG2124	cytochrome p450
EG219_RS10600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG219_RS10600	COG3321	synthase
EG219_RS10600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EG219_RS10600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS10600	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS10605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS10605	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS10605	COG3321	synthase
EG219_RS10605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EG219_RS10605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG219_RS10610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS10610	COG0318	PFAM AMP-dependent synthetase and ligase
EG219_RS10610	COG3321	synthase
EG219_RS10610	COG0300	oxidoreductase activity
EG219_RS10610	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS10620	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS10620	COG3321	synthase
EG219_RS10620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EG219_RS10620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS10620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG219_RS10625	COG0300	oxidoreductase activity
EG219_RS10625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS10625	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS10625	COG3321	synthase
EG219_RS10625	COG0318	PFAM AMP-dependent synthetase and ligase
EG219_RS10635	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS10640	COG0318	PFAM AMP-dependent synthetase and ligase
EG219_RS10655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EG219_RS10655	COG2070	2-Nitropropane dioxygenase
EG219_RS10665	COG0250	Participates in transcription elongation, termination and antitermination
EG219_RS10690	COG0596	Alpha beta hydrolase
EG219_RS10705	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EG219_RS10710	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EG219_RS10725	COG0706	membrane insertase activity
EG219_RS10730	COG2195	Cleaves the N-terminal amino acid of tripeptides
EG219_RS10735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EG219_RS10740	COG0346	lactoylglutathione lyase activity
EG219_RS10745	COG1376	ErfK ybiS ycfS ynhG family protein
EG219_RS10750	COG4129	membrane
EG219_RS10755	COG1126	abc transporter atp-binding protein
EG219_RS10760	COG0765	amino acid transport
EG219_RS10765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EG219_RS10775	COG1597	lipid kinase activity
EG219_RS10780	COG0508	dehydrogenase complex catalyzes the overall conversion of
EG219_RS10785	COG0022	dehydrogenase e1 component
EG219_RS10790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EG219_RS10795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EG219_RS10800	COG3426	butyrate kinase activity
EG219_RS10805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EG219_RS10810	COG0280	phosphate acetyltransferase
EG219_RS10815	COG3290	protein histidine kinase activity
EG219_RS10815	COG3829	transcription factor binding
EG219_RS10825	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EG219_RS10830	COG2079	MmgE PrpD family protein
EG219_RS10835	COG0372	Belongs to the citrate synthase family
EG219_RS10840	COG1960	acyl-CoA dehydrogenase activity
EG219_RS10845	COG1250	3-hydroxyacyl-CoA dehydrogenase
EG219_RS10850	COG0183	Belongs to the thiolase family
EG219_RS10855	COG0584	glycerophosphoryl diester phosphodiesterase
EG219_RS10860	COG0860	N-Acetylmuramoyl-L-alanine amidase
EG219_RS10880	COG1902	pentaerythritol trinitrate reductase activity
EG219_RS10895	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EG219_RS10905	COG0745	RESPONSE REGULATOR receiver
EG219_RS10910	COG0750	zinc metalloprotease
EG219_RS10915	COG0497	DNA recombination
EG219_RS10925	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EG219_RS10935	COG0142	geranyltranstransferase activity
EG219_RS10945	COG1570	exodeoxyribonuclease VII activity
EG219_RS10960	COG1302	Protein conserved in bacteria
EG219_RS10965	COG0439	Biotin carboxylase
EG219_RS10970	COG0511	ligase activity, forming carbon-carbon bonds
EG219_RS11010	COG3854	ATPases associated with a variety of cellular activities
EG219_RS11025	COG0006	proline dipeptidase activity
EG219_RS11035	COG3872	metal-dependent enzyme
EG219_RS11045	COG1752	Esterase of the alpha-beta hydrolase superfamily
EG219_RS11060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EG219_RS11080	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EG219_RS11095	COG1396	sequence-specific DNA binding
EG219_RS11105	COG0681	Belongs to the peptidase S26 family
EG219_RS11130	COG4940	Competence protein ComGF
EG219_RS11140	COG4970	Tfp pilus assembly protein FimT
EG219_RS11145	COG4537	Required for transformation and DNA binding
EG219_RS11150	COG1459	type II secretion system
EG219_RS11155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EG219_RS11160	COG0598	Magnesium transport protein CorA
EG219_RS11165	COG1253	flavin adenine dinucleotide binding
EG219_RS11170	COG1366	Belongs to the anti-sigma-factor antagonist family
EG219_RS11180	COG1393	Belongs to the ArsC family
EG219_RS11190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG219_RS11200	COG0011	TIGRFAM Protein of
EG219_RS11210	COG2866	Carboxypeptidase
EG219_RS11215	COG1940	carbohydrate kinase activity
EG219_RS11220	COG4483	Protein conserved in bacteria
EG219_RS11225	COG1757	Na H antiporter
EG219_RS11235	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EG219_RS11250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EG219_RS11255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EG219_RS11260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EG219_RS11265	COG0581	inorganic phosphate transmembrane transporter activity
EG219_RS11270	COG0573	inorganic phosphate transmembrane transporter activity
EG219_RS11275	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EG219_RS11285	COG0477	Major facilitator Superfamily
EG219_RS11290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EG219_RS11295	COG2839	Protein conserved in bacteria
EG219_RS11300	COG5521	maltodextrose utilization protein MalA
EG219_RS11305	COG1388	LysM domain
EG219_RS11315	COG4709	membrane
EG219_RS11320	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
EG219_RS11325	COG0735	belongs to the Fur family
EG219_RS11330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EG219_RS11345	COG0513	Belongs to the DEAD box helicase family
EG219_RS11360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EG219_RS11365	COG2384	SAM-dependent methyltransferase
EG219_RS11370	COG2010	Cytochrome c
EG219_RS11375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EG219_RS11380	COG0358	DNA primase activity
EG219_RS11395	COG0517	IMP dehydrogenase activity
EG219_RS11400	COG0751	glycine-tRNA ligase activity
EG219_RS11420	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EG219_RS11425	COG0295	cytidine deaminase activity
EG219_RS11430	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EG219_RS11440	COG1480	7TM receptor with intracellular HD hydrolase
EG219_RS11445	COG1702	phosphate starvation-inducible protein PhoH
EG219_RS11450	COG0561	phosphatase activity
EG219_RS11465	COG4864	UPF0365 protein
EG219_RS11470	COG1030	water channel activity
EG219_RS11475	COG1610	YqeY-like protein
EG219_RS11485	COG1283	sodium-dependent phosphate transmembrane transporter activity
EG219_RS11490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EG219_RS11495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EG219_RS11525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EG219_RS11540	COG0860	N-Acetylmuramoyl-L-alanine amidase
EG219_RS11555	COG1466	dna polymerase III delta subunit
EG219_RS11570	COG2333	competence protein COMEC
EG219_RS11570	COG0658	competence protein
EG219_RS11575	COG2131	deaminase
EG219_RS11580	COG1555	photosystem II stabilization
EG219_RS11580	COG1596	polysaccharide export
EG219_RS11585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EG219_RS11590	COG2226	methyltransferase
EG219_RS11595	COG0799	negative regulation of ribosome biogenesis
EG219_RS11600	COG1713	HD superfamily hydrolase involved in NAD metabolism
EG219_RS11610	COG1534	Rna-binding protein
EG219_RS11615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EG219_RS11620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EG219_RS11625	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EG219_RS11635	COG2755	lipolytic protein G-D-S-L family
EG219_RS11645	COG0398	Pfam SNARE associated Golgi protein
EG219_RS11690	COG0563	adenylate kinase activity
EG219_RS11695	COG2814	Major facilitator Superfamily
EG219_RS11705	COG0456	acetyltransferase
EG219_RS11710	COG2318	DinB family
EG219_RS11720	COG0561	phosphatase activity
EG219_RS11725	COG0561	phosphatase activity
EG219_RS11735	COG1482	cell wall glycoprotein biosynthetic process
EG219_RS11740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EG219_RS11740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EG219_RS11740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EG219_RS11745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EG219_RS11745	COG3711	transcriptional antiterminator
EG219_RS11755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EG219_RS11760	COG0583	DNA-binding transcription factor activity
EG219_RS11765	COG2814	Major facilitator Superfamily
EG219_RS11770	COG2124	cytochrome p450
EG219_RS11770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EG219_RS11775	COG1309	transcriptional regulator
EG219_RS11780	COG2226	methyltransferase
EG219_RS11795	COG2116	formate transmembrane transporter activity
EG219_RS11800	COG5609	conserved protein (DUF2294)
EG219_RS11805	COG3383	formate dehydrogenase (NAD+) activity
EG219_RS11810	COG2427	Protein of unknown function (DUF1641)
EG219_RS11820	COG0626	cystathionine gamma-synthase activity
EG219_RS11825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EG219_RS11850	COG0768	penicillin binding
EG219_RS11865	COG0826	peptidase U32
EG219_RS11870	COG0826	peptidase U32
EG219_RS11875	COG4122	O-methyltransferase activity
EG219_RS11880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EG219_RS11895	COG4472	Bacterial protein of unknown function (DUF965)
EG219_RS11905	COG0628	permease
EG219_RS11910	COG1126	abc transporter atp-binding protein
EG219_RS11915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EG219_RS11920	COG0765	amino acid transport
EG219_RS11925	COG0765	amino acid transport
EG219_RS11940	COG3881	PFAM PRC-barrel domain
EG219_RS11945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EG219_RS11950	COG0457	Tetratricopeptide repeat
EG219_RS11960	COG1104	cysteine desulfurase activity
EG219_RS11965	COG1959	2 iron, 2 sulfur cluster binding
EG219_RS11970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EG219_RS11975	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EG219_RS11995	COG4991	sh3 domain protein
EG219_RS11995	COG3103	Sh3 type 3 domain protein
EG219_RS11995	COG0860	N-Acetylmuramoyl-L-alanine amidase
EG219_RS12005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EG219_RS12015	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EG219_RS12015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EG219_RS12020	COG5416	Lipopolysaccharide assembly protein A domain
EG219_RS12025	COG0490	domain, Protein
EG219_RS12030	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EG219_RS12030	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EG219_RS12040	COG2244	polysaccharide biosynthetic process
EG219_RS12045	COG2323	membrane
EG219_RS12055	COG1862	Preprotein translocase
EG219_RS12100	COG1388	LysM domain
EG219_RS12110	COG0157	Belongs to the NadC ModD family
EG219_RS12115	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EG219_RS12120	COG1104	cysteine desulfurase activity
EG219_RS12125	COG1827	regulation of RNA biosynthetic process
EG219_RS12130	COG0077	Prephenate dehydratase
EG219_RS12145	COG3290	protein histidine kinase activity
EG219_RS12150	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EG219_RS12155	COG2868	ribosomal protein
EG219_RS12165	COG1994	Peptidase M50
EG219_RS12170	COG0739	heme binding
EG219_RS12175	COG2894	cell division
EG219_RS12185	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EG219_RS12195	COG1077	Cell shape determining protein MreB Mrl
EG219_RS12215	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EG219_RS12220	COG0285	dihydrofolate synthase activity
EG219_RS12225	COG0525	valine-tRNA ligase activity
EG219_RS12235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EG219_RS12240	COG1388	LysM domain
EG219_RS12250	COG0113	porphobilinogen synthase activity
EG219_RS12255	COG1587	Uroporphyrinogen-III synthase
EG219_RS12265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EG219_RS12285	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EG219_RS12290	COG1067	ATP-dependent peptidase activity
EG219_RS12290	COG0470	DNA polymerase III
EG219_RS12305	COG0457	Tetratricopeptide repeat
EG219_RS12305	COG1477	protein flavinylation
EG219_RS12320	COG0473	3-isopropylmalate dehydrogenase activity
EG219_RS12335	COG0440	acetolactate synthase activity
EG219_RS12340	COG0028	Belongs to the TPP enzyme family
EG219_RS12365	COG0622	Phosphoesterase
EG219_RS12370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EG219_RS12380	COG5401	PFAM Sporulation and spore germination
EG219_RS12390	COG1846	Transcriptional regulator
EG219_RS12395	COG2197	response regulator
EG219_RS12400	COG0824	Thioesterase
EG219_RS12405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EG219_RS12410	COG1053	succinate dehydrogenase
EG219_RS12415	COG2009	succinate dehydrogenase
EG219_RS12420	COG1719	4-vinyl reductase, 4VR
EG219_RS12425	COG0527	aspartate kinase activity
EG219_RS12440	COG3118	belongs to the thioredoxin family
EG219_RS12445	COG3534	alpha-L-arabinofuranosidase
EG219_RS12450	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EG219_RS12455	COG2086	electron transfer activity
EG219_RS12460	COG1024	Enoyl-CoA hydratase
EG219_RS12465	COG1309	transcriptional regulator
EG219_RS12470	COG0318	PFAM AMP-dependent synthetase and ligase
EG219_RS12480	COG3766	membrane
EG219_RS12490	COG1796	DNA polymerase
EG219_RS12490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EG219_RS12495	COG1286	toxin biosynthetic process
EG219_RS12510	COG0072	phenylalanine-tRNA ligase activity
EG219_RS12510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG219_RS12515	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EG219_RS12520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EG219_RS12530	COG3835	regulator
EG219_RS12535	COG0277	FAD linked oxidase domain protein
EG219_RS12540	COG0247	lactate metabolic process
EG219_RS12545	COG1966	Carbon starvation protein
EG219_RS12550	COG3534	alpha-L-arabinofuranosidase
EG219_RS12555	COG0395	ABC-type sugar transport system, permease component
EG219_RS12560	COG1175	transmembrane transport
EG219_RS12565	COG1653	transport
EG219_RS12575	COG0647	UMP catabolic process
EG219_RS12580	COG0235	Class ii aldolase
EG219_RS12585	COG1069	ribulokinase activity
EG219_RS12590	COG2160	L-arabinose isomerase activity
EG219_RS12595	COG3507	Belongs to the glycosyl hydrolase 43 family
EG219_RS12600	COG1363	Peptidase, m42
EG219_RS12610	COG3326	Membrane
EG219_RS12615	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EG219_RS12625	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EG219_RS12630	COG1346	cytolysis
EG219_RS12635	COG1380	Effector of murein hydrolase LrgA
EG219_RS12640	COG3279	Response regulator of the LytR AlgR family
EG219_RS12645	COG3275	phosphorelay sensor kinase activity
EG219_RS12650	COG1011	Hydrolase
EG219_RS12665	COG0398	Pfam SNARE associated Golgi protein
EG219_RS12670	COG1484	DNA-dependent DNA replication
EG219_RS12675	COG3611	Membrane attachment protein
EG219_RS12690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EG219_RS12695	COG1733	regulation of RNA biosynthetic process
EG219_RS12700	COG2814	Major facilitator Superfamily
EG219_RS12705	COG0656	L-ascorbic acid biosynthetic process
EG219_RS12710	COG0237	dephospho-CoA kinase activity
EG219_RS12715	COG1971	Probably functions as a manganese efflux pump
EG219_RS12720	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EG219_RS12725	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EG219_RS12725	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EG219_RS12730	COG5002	protein histidine kinase activity
EG219_RS12735	COG0745	RESPONSE REGULATOR receiver
EG219_RS12745	COG0538	isocitrate dehydrogenase activity
EG219_RS12750	COG0372	Belongs to the citrate synthase family
EG219_RS12765	COG0628	permease
EG219_RS12770	COG3030	protein affecting phage T7 exclusion by the F plasmid
EG219_RS12775	COG0469	pyruvate kinase activity
EG219_RS12795	COG0281	malic enzyme
EG219_RS12800	COG0587	DNA-directed DNA polymerase activity
EG219_RS12820	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EG219_RS12830	COG4109	DRTGG domain
EG219_RS12840	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS12855	COG0521	Mo-molybdopterin cofactor biosynthetic process
EG219_RS12865	COG0827	DNA restriction-modification system
EG219_RS12870	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EG219_RS12875	COG3874	Sporulation protein YtfJ
EG219_RS12885	COG1714	RDD family
EG219_RS12890	COG0616	signal peptide processing
EG219_RS12895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EG219_RS12900	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EG219_RS12905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EG219_RS12920	COG1104	cysteine desulfurase activity
EG219_RS12925	COG1114	Component of the transport system for branched-chain amino acids
EG219_RS12935	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EG219_RS12940	COG1309	transcriptional regulator
EG219_RS12945	COG1956	GAF domain-containing protein
EG219_RS12950	COG2203	Gaf domain
EG219_RS12950	COG2199	diguanylate cyclase activity
EG219_RS12965	COG1012	belongs to the aldehyde dehydrogenase family
EG219_RS12975	COG1017	nitric oxide dioxygenase activity
EG219_RS12975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EG219_RS12985	COG0693	protein deglycase activity
EG219_RS13000	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EG219_RS13005	COG1378	Sugar-specific transcriptional regulator TrmB
EG219_RS13030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EG219_RS13035	COG0454	-acetyltransferase
EG219_RS13040	COG0517	IMP dehydrogenase activity
EG219_RS13045	COG0123	including yeast histone deacetylase and acetoin utilization protein
EG219_RS13050	COG1360	Flagellar Motor Protein
EG219_RS13055	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EG219_RS13060	COG1609	Transcriptional regulator
EG219_RS13065	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EG219_RS13065	COG1605	Chorismate mutase
EG219_RS13070	COG3118	belongs to the thioredoxin family
EG219_RS13075	COG4980	gas vesicle protein
EG219_RS13080	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EG219_RS13090	COG1674	ftsk spoiiie
EG219_RS13095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG219_RS13105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG219_RS13115	COG1363	Peptidase, m42
EG219_RS13120	COG5584	Small secreted protein
EG219_RS13125	COG0281	malic enzyme
EG219_RS13130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG219_RS13145	COG0510	thiamine kinase activity
EG219_RS13150	COG1597	lipid kinase activity
EG219_RS13160	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EG219_RS13165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EG219_RS13170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EG219_RS13175	COG2252	PERMEase
EG219_RS13180	COG4473	ABC transporter
EG219_RS13185	COG1131	(ABC) transporter
EG219_RS13190	COG1349	DNA-binding transcription factor activity
EG219_RS13195	COG1187	pseudouridine synthase activity
EG219_RS13200	COG2244	polysaccharide biosynthetic process
EG219_RS13205	COG2081	HI0933 family
EG219_RS13210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EG219_RS13220	COG1609	Transcriptional regulator
EG219_RS13225	COG1653	transport
EG219_RS13230	COG1175	transmembrane transport
EG219_RS13235	COG0395	ABC-type sugar transport system, permease component
EG219_RS13240	COG1486	melibiose metabolic process
EG219_RS13250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EG219_RS13265	COG2202	Pas domain
EG219_RS13265	COG1366	Belongs to the anti-sigma-factor antagonist family
EG219_RS13270	COG2814	Major facilitator Superfamily
EG219_RS13275	COG5522	Integral membrane protein (intg_mem_TP0381)
EG219_RS13280	COG0577	efflux transmembrane transporter activity
EG219_RS13285	COG1136	(ABC) transporter
EG219_RS13290	COG2205	protein histidine kinase activity
EG219_RS13295	COG0745	RESPONSE REGULATOR receiver
EG219_RS13300	COG0577	efflux transmembrane transporter activity
EG219_RS13305	COG1136	(ABC) transporter
EG219_RS13325	COG1131	(ABC) transporter
EG219_RS13330	COG1725	Transcriptional regulator
EG219_RS13340	COG0640	Transcriptional regulator
EG219_RS13345	COG0477	Major facilitator Superfamily
EG219_RS13350	COG1242	4 iron, 4 sulfur cluster binding
EG219_RS13355	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EG219_RS13365	COG0584	glycerophosphoryl diester phosphodiesterase
EG219_RS13375	COG2267	carboxylic ester hydrolase activity
EG219_RS13380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EG219_RS13385	COG1113	amino acid transport
EG219_RS13390	COG0367	asparagine synthase
EG219_RS13410	COG1506	peptidase
EG219_RS13415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EG219_RS13420	COG1116	anion transmembrane transporter activity
EG219_RS13425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EG219_RS13430	COG0494	nUDIX hydrolase
EG219_RS13435	COG4824	toxin secretion phage lysis holin
EG219_RS13440	COG0783	Belongs to the Dps family
EG219_RS13465	COG0288	reversible hydration of carbon dioxide
EG219_RS13475	COG1271	oxidase subunit
EG219_RS13480	COG1294	oxidase, subunit
EG219_RS13495	COG4948	Mandelate Racemase Muconate Lactonizing
EG219_RS13505	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EG219_RS13510	COG0596	Alpha beta hydrolase
EG219_RS13520	COG1169	isochorismate synthase
EG219_RS13525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EG219_RS13530	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EG219_RS13655	COG3859	Proton-coupled thiamine transporter YuaJ
EG219_RS13660	COG2268	Band 7 protein
EG219_RS13665	COG1585	Membrane protein implicated in regulation of membrane protease activity
EG219_RS13670	COG2318	DinB family
EG219_RS13680	COG1454	alcohol dehydrogenase
EG219_RS13685	COG1012	belongs to the aldehyde dehydrogenase family
EG219_RS13690	COG1510	regulation of RNA biosynthetic process
EG219_RS13700	COG0569	domain protein
EG219_RS13705	COG1705	Flagellar rod assembly protein muramidase FlgJ
EG219_RS13710	COG1017	nitric oxide dioxygenase activity
EG219_RS13710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EG219_RS13735	COG0628	permease
EG219_RS13740	COG0673	inositol 2-dehydrogenase activity
EG219_RS13745	COG0693	protein deglycase activity
EG219_RS13750	COG0840	transmembrane signaling receptor activity
EG219_RS13755	COG0840	transmembrane signaling receptor activity
EG219_RS13760	COG0840	transmembrane signaling receptor activity
EG219_RS13765	COG0840	transmembrane signaling receptor activity
EG219_RS13780	COG2070	2-Nitropropane dioxygenase
EG219_RS13785	COG0432	Pfam Uncharacterised protein family UPF0047
EG219_RS13790	COG0366	Alpha amylase catalytic
EG219_RS13795	COG1253	flavin adenine dinucleotide binding
EG219_RS13800	COG2738	Putative neutral zinc metallopeptidase
EG219_RS13815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EG219_RS13845	COG1335	isochorismatase
EG219_RS13850	COG1979	alcohol dehydrogenase
EG219_RS13855	COG1979	alcohol dehydrogenase
EG219_RS13860	COG2155	Conserved Protein
EG219_RS13865	COG1098	S1 RNA binding domain
EG219_RS13870	COG0436	Aminotransferase
EG219_RS13875	COG1522	sequence-specific DNA binding
EG219_RS13880	COG2267	carboxylic ester hydrolase activity
EG219_RS13890	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EG219_RS13895	COG2205	protein histidine kinase activity
EG219_RS13905	COG5018	Exonuclease
EG219_RS13910	COG2814	Major facilitator Superfamily
EG219_RS13915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EG219_RS13920	COG3011	Protein conserved in bacteria
EG219_RS13930	COG3290	protein histidine kinase activity
EG219_RS13935	COG4565	transcriptional regulatory protein
EG219_RS13940	COG1744	ABC transporter substrate-binding protein PnrA-like
EG219_RS13945	COG3845	ABC transporter
EG219_RS13950	COG4603	Belongs to the binding-protein-dependent transport system permease family
EG219_RS13955	COG1079	Belongs to the binding-protein-dependent transport system permease family
EG219_RS13965	COG2111	Na H antiporter
EG219_RS13965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EG219_RS13970	COG2111	Na H antiporter
EG219_RS13975	COG1006	Multisubunit Na H antiporter MnhC subunit
EG219_RS13980	COG0651	ATP synthesis coupled electron transport
EG219_RS13985	COG1863	multisubunit Na H antiporter MnhE subunit
EG219_RS13990	COG2212	antiporter activity
EG219_RS13995	COG1320	monovalent cation:proton antiporter activity
EG219_RS14000	COG2050	protein possibly involved in aromatic compounds catabolism
EG219_RS14005	COG2197	response regulator
EG219_RS14030	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EG219_RS14035	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EG219_RS14040	COG1335	isochorismatase
EG219_RS14045	COG5506	Protein of unknown function (DUF1694)
EG219_RS14060	COG0628	permease
EG219_RS14070	COG1418	mRNA catabolic process
EG219_RS14075	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS14085	COG1511	domain protein
EG219_RS14090	COG1674	ftsk spoiiie
EG219_RS14090	COG0433	COG0433 Predicted ATPase
EG219_RS14095	COG4499	WXG100 protein secretion system (Wss), protein YukC
EG219_RS14100	COG5417	Belongs to the EsaB family
EG219_RS14105	COG4842	Belongs to the WXG100 family
EG219_RS14110	COG2508	Transcriptional regulator
EG219_RS14110	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EG219_RS14115	COG0686	Belongs to the AlaDH PNT family
EG219_RS14120	COG5634	Uncharacterized conserved protein (DUF2278)
EG219_RS14125	COG3251	PFAM MbtH domain protein
EG219_RS14130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG219_RS14135	COG3433	isochorismatase activity
EG219_RS14135	COG1535	isochorismatase
EG219_RS14140	COG1021	2,3-dihydroxybenzoate-AMP ligase
EG219_RS14145	COG1169	isochorismate synthase
EG219_RS14150	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS14155	COG2819	hydrolase of the alpha beta superfamily
EG219_RS14160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EG219_RS14165	COG1268	BioY protein
EG219_RS14170	COG2056	Na+-H+ antiporter family
EG219_RS14180	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EG219_RS14185	COG3584	3D domain protein
EG219_RS14200	COG1252	NADH dehydrogenase
EG219_RS14230	COG1131	(ABC) transporter
EG219_RS14250	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EG219_RS14255	COG0316	Belongs to the HesB IscA family
EG219_RS14265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EG219_RS14275	COG1252	NADH dehydrogenase
EG219_RS14280	COG4837	Protein of unknown function (DUF1462)
EG219_RS14285	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EG219_RS14290	COG0823	Involved in the tonB-independent uptake of proteins
EG219_RS14290	COG1506	peptidase
EG219_RS14290	COG4946	Tricorn protease homolog
EG219_RS14300	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EG219_RS14305	COG0460	homoserine dehydrogenase
EG219_RS14310	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EG219_RS14315	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EG219_RS14320	COG0647	UMP catabolic process
EG219_RS14325	COG2445	Protein of unknown function DUF86
EG219_RS14330	COG4470	Protein conserved in bacteria
EG219_RS14345	COG0739	heme binding
EG219_RS14355	COG0737	Belongs to the 5'-nucleotidase family
EG219_RS14360	COG0730	response to heat
EG219_RS14365	COG1801	Protein of unknown function DUF72
EG219_RS14380	COG2508	Transcriptional regulator
EG219_RS14385	COG2814	Major facilitator Superfamily
EG219_RS14390	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EG219_RS14395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EG219_RS14400	COG2356	endonuclease I
EG219_RS14405	COG3842	ATPase activity
EG219_RS14410	COG2188	Transcriptional regulator
EG219_RS14415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EG219_RS14420	COG0395	ABC-type sugar transport system, permease component
EG219_RS14425	COG1175	transmembrane transport
EG219_RS14430	COG1653	transport
EG219_RS14435	COG2222	sugar isomerase
EG219_RS14440	COG0789	Transcriptional regulator
EG219_RS14455	COG0322	excinuclease ABC activity
EG219_RS14460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EG219_RS14465	COG2226	methyltransferase
EG219_RS14480	COG3409	Peptidoglycan-binding domain 1 protein
EG219_RS14485	COG0719	Fe-S assembly protein
EG219_RS14490	COG0822	iron-sulfur transferase activity
EG219_RS14495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EG219_RS14500	COG0719	Fe-S assembly protein
EG219_RS14505	COG0396	ATPase activity
EG219_RS14515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EG219_RS14520	COG1464	Belongs to the NlpA lipoprotein family
EG219_RS14525	COG2011	ABC-type metal ion transport system permease component
EG219_RS14530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EG219_RS14540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EG219_RS14545	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EG219_RS14560	COG1393	Belongs to the ArsC family
EG219_RS14565	COG1960	acyl-CoA dehydrogenase activity
EG219_RS14570	COG0183	Belongs to the thiolase family
EG219_RS14575	COG1250	3-hydroxyacyl-CoA dehydrogenase
EG219_RS14575	COG1024	Enoyl-CoA hydratase
EG219_RS14595	COG5577	PFAM Coat F domain
EG219_RS14600	COG1846	Transcriptional regulator
EG219_RS14605	COG0477	Major facilitator Superfamily
EG219_RS14610	COG0583	DNA-binding transcription factor activity
EG219_RS14630	COG1120	ATPase activity
EG219_RS14645	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS14650	COG0783	Belongs to the Dps family
EG219_RS14655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EG219_RS14665	COG0745	RESPONSE REGULATOR receiver
EG219_RS14670	COG2770	Histidine kinase
EG219_RS14670	COG2205	protein histidine kinase activity
EG219_RS14680	COG1309	transcriptional regulator
EG219_RS14685	COG0114	fumarate hydratase activity
EG219_RS14695	COG0697	spore germination
EG219_RS14700	COG0814	amino acid
EG219_RS14710	COG2197	response regulator
EG219_RS14715	COG4585	Histidine kinase
EG219_RS14720	COG4758	membrane
EG219_RS14725	COG3595	metallopeptidase activity
EG219_RS14730	COG1842	Phage shock protein A
EG219_RS14735	COG4758	membrane
EG219_RS14740	COG2814	Major facilitator Superfamily
EG219_RS14745	COG2096	Adenosyltransferase
EG219_RS14750	COG1120	ATPase activity
EG219_RS14755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EG219_RS14760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EG219_RS14765	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS14770	COG3386	PFAM SMP-30 Gluconolaconase
EG219_RS14775	COG2205	protein histidine kinase activity
EG219_RS14780	COG0745	RESPONSE REGULATOR receiver
EG219_RS14790	COG1191	sigma factor activity
EG219_RS14800	COG2140	Oxalate decarboxylase
EG219_RS14810	COG1120	ATPase activity
EG219_RS14815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EG219_RS14820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EG219_RS14825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EG219_RS14830	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EG219_RS14835	COG0531	amino acid
EG219_RS14850	COG1988	membrane-bound metal-dependent
EG219_RS14855	COG1368	sulfuric ester hydrolase activity
EG219_RS14860	COG1910	domain protein
EG219_RS14865	COG0725	ABC transporter, periplasmic molybdate-binding protein
EG219_RS14870	COG4149	molybdate abc transporter
EG219_RS14875	COG2197	response regulator
EG219_RS14880	COG3850	Histidine kinase
EG219_RS14885	COG1131	(ABC) transporter
EG219_RS14895	COG0842	Transport permease protein
EG219_RS14900	COG0656	L-ascorbic acid biosynthetic process
EG219_RS14925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EG219_RS14930	COG3973	AAA domain
EG219_RS14935	COG2860	membrane
EG219_RS14945	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EG219_RS14950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EG219_RS14955	COG2217	Heavy metal translocating P-type atpase
EG219_RS14960	COG2217	Heavy metal translocating P-type atpase
EG219_RS14965	COG2608	mercury ion transmembrane transporter activity
EG219_RS14970	COG1937	Protein conserved in bacteria
EG219_RS14975	COG0673	inositol 2-dehydrogenase activity
EG219_RS14995	COG2814	Major facilitator Superfamily
EG219_RS15010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EG219_RS15015	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EG219_RS15020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EG219_RS15025	COG1126	abc transporter atp-binding protein
EG219_RS15030	COG0765	amino acid transport
EG219_RS15035	COG0765	amino acid transport
EG219_RS15040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EG219_RS15045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EG219_RS15050	COG0454	-acetyltransferase
EG219_RS15055	COG0583	DNA-binding transcription factor activity
EG219_RS15060	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS15065	COG2732	(Barnase) inhibitor
EG219_RS15080	COG0557	exoribonuclease II activity
EG219_RS15085	COG1647	Serine aminopeptidase, S33
EG219_RS15090	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EG219_RS15095	COG1476	TRANSCRIPTIONal
EG219_RS15100	COG1396	sequence-specific DNA binding
EG219_RS15105	COG1396	sequence-specific DNA binding
EG219_RS15110	COG1733	regulation of RNA biosynthetic process
EG219_RS15135	COG1131	(ABC) transporter
EG219_RS15140	COG1174	glycine betaine transport
EG219_RS15145	COG1732	Glycine betaine
EG219_RS15150	COG1174	glycine betaine transport
EG219_RS15155	COG0517	IMP dehydrogenase activity
EG219_RS15155	COG1125	glycine betaine transport
EG219_RS15160	COG1510	regulation of RNA biosynthetic process
EG219_RS15165	COG1174	glycine betaine transport
EG219_RS15170	COG1732	Glycine betaine
EG219_RS15175	COG1174	glycine betaine transport
EG219_RS15180	COG1125	glycine betaine transport
EG219_RS15180	COG0517	IMP dehydrogenase activity
EG219_RS15185	COG1510	regulation of RNA biosynthetic process
EG219_RS15190	COG2095	MarC family integral membrane protein
EG219_RS15195	COG3064	Membrane
EG219_RS15200	COG4640	response to antibiotic
EG219_RS15205	COG0456	acetyltransferase
EG219_RS15220	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EG219_RS15240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EG219_RS15245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EG219_RS15255	COG2234	aminopeptidase activity
EG219_RS15275	COG0126	phosphoglycerate kinase activity
EG219_RS15285	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EG219_RS15290	COG2390	Transcriptional regulator
EG219_RS15295	COG2814	Major facilitator Superfamily
EG219_RS15300	COG1609	Transcriptional regulator
EG219_RS15305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EG219_RS15315	COG0583	DNA-binding transcription factor activity
EG219_RS15320	COG0697	spore germination
EG219_RS15325	COG1113	amino acid transport
EG219_RS15330	COG1737	Transcriptional regulator
EG219_RS15335	COG1070	Carbohydrate kinase
EG219_RS15365	COG2186	Transcriptional regulator
EG219_RS15370	COG1620	l-lactate permease
EG219_RS15375	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EG219_RS15385	COG5039	Polysaccharide pyruvyl transferase
EG219_RS15390	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EG219_RS15395	COG0110	maltose O-acetyltransferase activity
EG219_RS15400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EG219_RS15405	COG2244	polysaccharide biosynthetic process
EG219_RS15410	COG1216	Glycosyl transferase, family 2
EG219_RS15415	COG5039	Polysaccharide pyruvyl transferase
EG219_RS15420	COG1216	Glycosyl transferase, family 2
EG219_RS15430	COG0438	transferase activity, transferring glycosyl groups
EG219_RS15435	COG1215	transferase activity, transferring glycosyl groups
EG219_RS15440	COG0438	transferase activity, transferring glycosyl groups
EG219_RS15445	COG1086	Polysaccharide biosynthesis protein
EG219_RS15450	COG0489	protein tyrosine kinase activity
EG219_RS15455	COG3944	biosynthesis protein
EG219_RS15460	COG1396	sequence-specific DNA binding
EG219_RS15465	COG2272	Belongs to the type-B carboxylesterase lipase family
EG219_RS15470	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EG219_RS15475	COG2364	Membrane
EG219_RS15480	COG0456	acetyltransferase
EG219_RS15485	COG3479	Phenolic acid decarboxylase
EG219_RS15520	COG2223	nitrite transmembrane transporter activity
EG219_RS15525	COG1609	Transcriptional regulator
EG219_RS15535	COG0583	DNA-binding transcription factor activity
EG219_RS15540	COG2828	Protein conserved in bacteria
EG219_RS15545	COG2814	Major facilitator Superfamily
EG219_RS15545	COG0477	Major facilitator Superfamily
EG219_RS15550	COG1611	Belongs to the LOG family
EG219_RS15555	COG1694	Mazg nucleotide pyrophosphohydrolase
EG219_RS15560	COG0659	secondary active sulfate transmembrane transporter activity
EG219_RS15565	COG0288	reversible hydration of carbon dioxide
EG219_RS15575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EG219_RS15580	COG4290	ribonuclease
EG219_RS15585	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EG219_RS15590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EG219_RS15600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EG219_RS15610	COG1051	belongs to the nudix hydrolase family
EG219_RS15615	COG0492	ferredoxin-NADP+ reductase activity
EG219_RS15620	COG0791	NLP P60 protein
EG219_RS15620	COG3883	PFAM NLP P60 protein
EG219_RS15625	COG0457	Tetratricopeptide repeat
EG219_RS15630	COG5002	protein histidine kinase activity
EG219_RS15635	COG0745	RESPONSE REGULATOR receiver
EG219_RS15640	COG1132	(ABC) transporter
EG219_RS15645	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EG219_RS15645	COG0140	phosphoribosyl-ATP diphosphatase activity
EG219_RS15670	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EG219_RS15685	COG4990	cell redox homeostasis
EG219_RS15690	COG0110	maltose O-acetyltransferase activity
EG219_RS15710	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EG219_RS15720	COG2188	Transcriptional regulator
EG219_RS15725	COG1309	transcriptional regulator
EG219_RS15730	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EG219_RS15735	COG1950	PFAM Membrane protein of
EG219_RS15740	COG1983	PspC domain protein
EG219_RS15745	COG3595	metallopeptidase activity
EG219_RS15760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EG219_RS15770	COG4897	Protein conserved in bacteria
EG219_RS15775	COG3848	Pyruvate phosphate dikinase
EG219_RS15775	COG0574	Belongs to the PEP-utilizing enzyme family
EG219_RS15780	COG1309	transcriptional regulator
EG219_RS15785	COG2814	Major facilitator Superfamily
EG219_RS15800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EG219_RS15810	COG3409	Peptidoglycan-binding domain 1 protein
EG219_RS15810	COG0793	Belongs to the peptidase S41A family
EG219_RS15815	COG3420	alginic acid biosynthetic process
EG219_RS15820	COG2177	Part of the ABC transporter FtsEX involved in
EG219_RS15825	COG2884	Cell division ATP-binding protein ftsE
EG219_RS15830	COG2010	Cytochrome c
EG219_RS15835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EG219_RS15850	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EG219_RS15865	COG1516	flagellar protein fliS
EG219_RS15870	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EG219_RS15895	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EG219_RS15900	COG1256	bacterial-type flagellum assembly
EG219_RS15900	COG4786	Flagellar basal body rod
EG219_RS15905	COG3418	PFAM FlgN family protein
EG219_RS15910	COG2747	anti-sigma28 factor FlgM
EG219_RS15920	COG1040	competence protein
EG219_RS15930	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EG219_RS15935	COG1307	EDD domain protein, DegV family
EG219_RS15940	COG2197	response regulator
EG219_RS15945	COG4585	Histidine kinase
EG219_RS15950	COG1739	Uncharacterized protein family UPF0029
EG219_RS15955	COG1316	TRANSCRIPTIONal
EG219_RS15960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EG219_RS15965	COG0438	transferase activity, transferring glycosyl groups
EG219_RS15970	COG1215	transferase activity, transferring glycosyl groups
EG219_RS15975	COG3206	protein involved in exopolysaccharide biosynthesis
EG219_RS15980	COG3307	-O-antigen
EG219_RS15985	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EG219_RS15990	COG0297	glycogen (starch) synthase activity
EG219_RS15990	COG0438	transferase activity, transferring glycosyl groups
EG219_RS15995	COG2244	polysaccharide biosynthetic process
EG219_RS16005	COG2247	cell wall binding repeat
EG219_RS16005	COG0860	N-Acetylmuramoyl-L-alanine amidase
EG219_RS16010	COG2247	cell wall binding repeat
EG219_RS16010	COG2385	sporulation resulting in formation of a cellular spore
EG219_RS16020	COG1316	TRANSCRIPTIONal
EG219_RS16025	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EG219_RS16030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EG219_RS16035	COG1134	teichoic acid transport
EG219_RS16040	COG1682	transport, permease protein
EG219_RS16045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EG219_RS16055	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EG219_RS16060	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EG219_RS16065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EG219_RS16070	COG4193	domain, Protein
EG219_RS16075	COG1482	cell wall glycoprotein biosynthetic process
EG219_RS16080	COG0697	spore germination
EG219_RS16085	COG0814	amino acid
EG219_RS16095	COG1215	transferase activity, transferring glycosyl groups
EG219_RS16100	COG2814	Major facilitator Superfamily
EG219_RS16105	COG1316	TRANSCRIPTIONal
EG219_RS16110	COG0561	phosphatase activity
EG219_RS16115	COG2433	Pfam Transposase IS66
EG219_RS16120	COG0791	NLP P60 protein
EG219_RS16130	COG2843	Capsule synthesis protein
EG219_RS16140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EG219_RS16150	COG0697	spore germination
EG219_RS16155	COG0814	amino acid
EG219_RS16165	COG1609	Transcriptional regulator
EG219_RS16170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EG219_RS16180	COG1129	ABC transporter
EG219_RS16185	COG1172	Belongs to the binding-protein-dependent transport system permease family
EG219_RS16190	COG1879	ABC-type sugar transport system periplasmic component
EG219_RS16195	COG3103	Sh3 type 3 domain protein
EG219_RS16200	COG2249	NAD(P)H dehydrogenase (quinone) activity
EG219_RS16205	COG3527	Alpha-acetolactate decarboxylase
EG219_RS16210	COG0028	Belongs to the TPP enzyme family
EG219_RS16215	COG0583	DNA-binding transcription factor activity
EG219_RS16220	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EG219_RS16235	COG5337	Spore coat protein CotH
EG219_RS16245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EG219_RS16255	COG0405	Gamma-glutamyltransferase
EG219_RS16260	COG1522	sequence-specific DNA binding
EG219_RS16265	COG2059	Chromate
EG219_RS16270	COG2059	Chromate
EG219_RS16280	COG5444	nuclease activity
EG219_RS16305	COG3878	Protein conserved in bacteria
EG219_RS16310	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EG219_RS16315	COG4464	protein tyrosine phosphatase activity
EG219_RS16320	COG0489	protein tyrosine kinase activity
EG219_RS16325	COG3944	biosynthesis protein
EG219_RS16340	COG4715	Zinc finger, swim domain protein
EG219_RS16345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EG219_RS16350	COG0561	phosphatase activity
EG219_RS16355	COG1349	DNA-binding transcription factor activity
EG219_RS16360	COG0629	single-stranded DNA binding
EG219_RS16385	COG0457	Tetratricopeptide repeat
EG219_RS16390	COG4786	Flagellar basal body rod
EG219_RS16395	COG4786	Flagellar basal body rod
EG219_RS16400	COG1077	Cell shape determining protein MreB Mrl
EG219_RS16405	COG1609	Transcriptional regulator
EG219_RS16410	COG1846	Transcriptional regulator
EG219_RS16415	COG2814	Major facilitator Superfamily
EG219_RS16420	COG1953	Uracil, thiamine, allantoin
EG219_RS16425	COG0477	Major facilitator Superfamily
EG219_RS16430	COG1335	isochorismatase
EG219_RS16435	COG0004	ammonium transporteR
EG219_RS16440	COG0347	Belongs to the P(II) protein family
EG219_RS16445	COG0772	Belongs to the SEDS family
EG219_RS16450	COG0671	phosphoesterase, PA-phosphatase related
EG219_RS16460	COG0739	heme binding
EG219_RS16465	COG1247	-acetyltransferase
EG219_RS16480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EG219_RS16495	COG0726	polysaccharide deacetylase
EG219_RS16505	COG1959	2 iron, 2 sulfur cluster binding
EG219_RS16520	COG0831	urea catabolic process
EG219_RS16525	COG3237	CsbD-like
EG219_RS16530	COG1994	Peptidase M50
EG219_RS16535	COG0457	Tetratricopeptide repeat
EG219_RS16545	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EG219_RS16550	COG2304	oxidoreductase activity
EG219_RS16555	COG2304	oxidoreductase activity
EG219_RS16565	COG2385	sporulation resulting in formation of a cellular spore
EG219_RS16570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EG219_RS16580	COG4836	Membrane
EG219_RS16650	COG0698	ribose 5-phosphate isomerase
EG219_RS16655	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EG219_RS16665	COG0009	L-threonylcarbamoyladenylate synthase
EG219_RS16670	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EG219_RS16690	COG2890	protein-(glutamine-N5) methyltransferase activity
EG219_RS16695	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EG219_RS16700	COG0346	lactoylglutathione lyase activity
EG219_RS16705	COG0789	Transcriptional regulator
EG219_RS16710	COG0679	Auxin Efflux Carrier
EG219_RS16715	COG0281	malic enzyme
EG219_RS16730	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EG219_RS16735	COG1494	fructose-1,6-bisphosphatase
EG219_RS16740	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EG219_RS16750	COG0191	fructose-bisphosphate aldolase activity
EG219_RS16755	COG2204	response regulator
EG219_RS16760	COG4821	SIS domain
EG219_RS16775	COG0247	lactate metabolic process
EG219_RS16775	COG2181	nitrate reductase activity
EG219_RS16780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EG219_RS16795	COG1132	(ABC) transporter
EG219_RS16800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EG219_RS16810	COG2181	nitrate reductase activity
EG219_RS16815	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EG219_RS16820	COG1140	nitrate reductase beta subunit
EG219_RS16825	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EG219_RS16830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EG219_RS16840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EG219_RS16845	COG2223	nitrite transmembrane transporter activity
EG219_RS16905	COG0010	Belongs to the arginase family
EG219_RS16910	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EG219_RS16915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EG219_RS16930	COG1994	Peptidase M50
EG219_RS16935	COG1942	4-Oxalocrotonate Tautomerase
EG219_RS16940	COG1846	Transcriptional regulator
EG219_RS16950	COG0531	amino acid
EG219_RS16955	COG3465	dGTPase activity
EG219_RS16960	COG1078	dGTPase activity
EG219_RS16975	COG1695	Transcriptional regulator
EG219_RS16985	COG1131	(ABC) transporter
EG219_RS16990	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EG219_RS17020	COG0583	DNA-binding transcription factor activity
EG219_RS17025	COG2855	membrane
EG219_RS17030	COG0280	phosphate acetyltransferase
EG219_RS17040	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS17045	COG0436	Aminotransferase
EG219_RS17075	COG2814	Major facilitator Superfamily
EG219_RS17080	COG2814	Major facilitator Superfamily
EG219_RS17085	COG0833	amino acid
EG219_RS17090	COG4187	Peptidase family M20/M25/M40
EG219_RS17095	COG1012	belongs to the aldehyde dehydrogenase family
EG219_RS17100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EG219_RS17110	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EG219_RS17115	COG1091	dTDP-4-dehydrorhamnose reductase activity
EG219_RS17120	COG1088	dTDP-glucose 4,6-dehydratase activity
EG219_RS17125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EG219_RS17130	COG3980	spore coat polysaccharide biosynthesis protein
EG219_RS17135	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
EG219_RS17140	COG2089	acid synthase
EG219_RS17145	COG0456	acetyltransferase
EG219_RS17150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EG219_RS17155	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EG219_RS17160	COG0463	Glycosyl transferase, family 2
EG219_RS17170	COG2363	Small membrane protein
EG219_RS17175	COG2233	PERMEase
EG219_RS17190	COG1216	Glycosyl transferase, family 2
EG219_RS17205	COG1695	Transcriptional regulator
EG219_RS17210	COG0351	phosphomethylpyrimidine kinase
EG219_RS17220	COG1621	beta-fructofuranosidase activity
EG219_RS17225	COG1263	PTS System
EG219_RS17225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EG219_RS17230	COG3711	transcriptional antiterminator
EG219_RS17240	COG1404	Belongs to the peptidase S8 family
EG219_RS17245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EG219_RS17250	COG0778	Nitroreductase
EG219_RS17255	COG0772	Belongs to the SEDS family
EG219_RS17260	COG0454	-acetyltransferase
EG219_RS17280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EG219_RS17285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EG219_RS17290	COG2261	transglycosylase associated protein
EG219_RS17295	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EG219_RS17305	COG2246	polysaccharide biosynthetic process
EG219_RS17310	COG1309	transcriptional regulator
EG219_RS17330	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EG219_RS17335	COG2837	iron assimilation
EG219_RS17340	COG2822	iron ion transport
EG219_RS17355	COG0583	DNA-binding transcription factor activity
EG219_RS17365	COG1346	cytolysis
EG219_RS17370	COG4895	conserved protein (DUF2196)
EG219_RS17375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EG219_RS17380	COG0346	lactoylglutathione lyase activity
EG219_RS17385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EG219_RS17390	COG1404	Belongs to the peptidase S8 family
EG219_RS17395	COG1442	glycosyl transferase family 8
EG219_RS17400	COG2357	RelA SpoT domain protein
EG219_RS17405	COG1575	Belongs to the MenA family. Type 1 subfamily
EG219_RS17430	COG1696	Membrane protein involved in D-alanine export
EG219_RS17440	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EG219_RS17445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EG219_RS17450	COG1486	melibiose metabolic process
EG219_RS17455	COG1447	Phosphotransferase system cellobiose-specific component IIA
EG219_RS17460	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EG219_RS17465	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EG219_RS17470	COG3711	transcriptional antiterminator
EG219_RS17470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EG219_RS17485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EG219_RS17490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EG219_RS17500	COG0640	Transcriptional regulator
EG219_RS17505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EG219_RS17515	COG1447	Phosphotransferase system cellobiose-specific component IIA
EG219_RS17520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EG219_RS17525	COG2723	6-phospho-beta-galactosidase activity
EG219_RS17530	COG1940	carbohydrate kinase activity
EG219_RS17535	COG1482	cell wall glycoprotein biosynthetic process
EG219_RS17545	COG0753	catalase activity
EG219_RS17550	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EG219_RS17555	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EG219_RS17560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EG219_RS17565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EG219_RS17570	COG4988	ABC transporter
EG219_RS17575	COG1294	oxidase, subunit
EG219_RS17580	COG1271	oxidase subunit
EG219_RS17585	COG3493	citrate carrier protein
EG219_RS17590	COG0726	polysaccharide deacetylase
EG219_RS17595	COG3842	ATPase activity
EG219_RS17600	COG2508	Transcriptional regulator
EG219_RS17605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EG219_RS17615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EG219_RS17625	COG4894	glucomannan catabolic process
EG219_RS17630	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EG219_RS17635	COG0500	methyltransferase
EG219_RS17640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EG219_RS17655	COG0693	protein deglycase activity
EG219_RS17655	COG0753	catalase activity
EG219_RS17660	COG2851	Citrate transporter
EG219_RS17665	COG2273	Hydrolase Family 16
EG219_RS17670	COG3711	transcriptional antiterminator
EG219_RS17675	COG2270	Major facilitator Superfamily
EG219_RS17680	COG0513	Belongs to the DEAD box helicase family
EG219_RS17720	COG0697	spore germination
EG219_RS17725	COG0589	response to stress
EG219_RS17735	COG0494	nUDIX hydrolase
EG219_RS17740	COG3507	Belongs to the glycosyl hydrolase 43 family
EG219_RS17765	COG0010	Belongs to the arginase family
EG219_RS17770	COG0833	amino acid
EG219_RS17775	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EG219_RS17780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EG219_RS17790	COG2390	Transcriptional regulator
EG219_RS17795	COG0561	phosphatase activity
EG219_RS17825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EG219_RS17830	COG5294	Protein conserved in bacteria
EG219_RS17835	COG0577	efflux transmembrane transporter activity
EG219_RS17840	COG1136	(ABC) transporter
EG219_RS17845	COG2205	protein histidine kinase activity
EG219_RS17850	COG0745	RESPONSE REGULATOR receiver
EG219_RS17865	COG1082	Xylose isomerase domain protein TIM barrel
EG219_RS17875	COG2814	Major facilitator Superfamily
EG219_RS17905	COG1349	DNA-binding transcription factor activity
EG219_RS17910	COG0667	Aldo Keto reductase
EG219_RS17915	COG2814	Major facilitator Superfamily
EG219_RS17930	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS17935	COG2197	response regulator
EG219_RS17940	COG4585	Histidine kinase
EG219_RS17945	COG3239	Fatty acid desaturase
EG219_RS17950	COG1309	transcriptional regulator
EG219_RS17955	COG1012	belongs to the aldehyde dehydrogenase family
EG219_RS17960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EG219_RS17970	COG0640	Transcriptional regulator
EG219_RS17975	COG2814	Major facilitator Superfamily
EG219_RS17980	COG1714	RDD family
EG219_RS17990	COG0450	alkyl hydroperoxide reductase
EG219_RS17995	COG3634	alkyl hydroperoxide reductase activity
EG219_RS18000	COG1113	amino acid transport
EG219_RS18010	COG2080	2 iron, 2 sulfur cluster binding
EG219_RS18025	COG2068	MobA-Related Protein
EG219_RS18030	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EG219_RS18060	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EG219_RS18065	COG0667	Aldo Keto reductase
EG219_RS18070	COG0456	acetyltransferase
EG219_RS18075	COG0457	Tetratricopeptide repeat
EG219_RS18080	COG0010	Belongs to the arginase family
EG219_RS18085	COG0833	amino acid
EG219_RS18090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EG219_RS18095	COG3829	transcription factor binding
EG219_RS18105	COG0488	(ABC) transporter
EG219_RS18120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EG219_RS18125	COG3850	Histidine kinase
EG219_RS18125	COG5002	protein histidine kinase activity
EG219_RS18130	COG0745	RESPONSE REGULATOR receiver
EG219_RS18135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EG219_RS18140	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EG219_RS18145	COG4853	Protein conserved in bacteria
EG219_RS18150	COG4863	YycH protein
EG219_RS18155	COG5002	protein histidine kinase activity
EG219_RS18160	COG0745	RESPONSE REGULATOR receiver
EG219_RS18195	COG0346	lactoylglutathione lyase activity
EG219_RS18200	COG0305	Participates in initiation and elongation during chromosome replication
EG219_RS18220	COG3093	addiction module antidote protein HigA
EG219_RS18225	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EG219_RS18240	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EG219_RS18245	COG0438	transferase activity, transferring glycosyl groups
EG219_RS18265	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EG219_RS18270	COG4241	membrane
EG219_RS18280	COG5577	PFAM Coat F domain
EG219_RS18285	COG1733	regulation of RNA biosynthetic process
EG219_RS18295	COG0697	spore germination
EG219_RS18300	COG1621	beta-fructofuranosidase activity
EG219_RS18305	COG1621	beta-fructofuranosidase activity
EG219_RS18310	COG1802	Transcriptional regulator
EG219_RS18315	COG2318	DinB family
EG219_RS18320	COG2211	Major facilitator Superfamily
EG219_RS18330	COG0778	Nitroreductase
EG219_RS18335	COG1846	Transcriptional regulator
EG219_RS18340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EG219_RS18345	COG1846	Transcriptional regulator
EG219_RS18355	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EG219_RS18360	COG0583	DNA-binding transcription factor activity
EG219_RS18365	COG1028	Short-chain dehydrogenase reductase Sdr
EG219_RS18370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EG219_RS18375	COG0697	spore germination
EG219_RS18380	COG1090	epimerase
EG219_RS18385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EG219_RS18390	COG1959	2 iron, 2 sulfur cluster binding
EG219_RS18395	COG1331	Highly conserved protein containing a thioredoxin domain
EG219_RS18400	COG1266	CAAX protease self-immunity
EG219_RS18405	COG2814	Major facilitator Superfamily
EG219_RS18405	COG0477	Major facilitator Superfamily
EG219_RS18410	COG0346	lactoylglutathione lyase activity
EG219_RS18415	COG1609	Transcriptional regulator
EG219_RS18420	COG0708	Exodeoxyribonuclease III
EG219_RS18425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EG219_RS18430	COG2169	Transcriptional regulator
EG219_RS18440	COG0629	single-stranded DNA binding
EG219_RS18450	COG0012	GTP binding
EG219_RS18455	COG0243	molybdopterin cofactor binding
EG219_RS18460	COG4481	Protein conserved in bacteria
EG219_RS18465	COG3949	Membrane
EG219_RS18480	COG1475	DNA binding
EG219_RS18485	COG1192	Involved in chromosome partitioning
EG219_RS18510	COG1847	R3H domain protein
EG219_RS18515	COG0706	membrane insertase activity