locus-tag	class	description
LXH20_RS00010	COG0592	DNA-directed DNA polymerase activity
LXH20_RS00015	COG2501	S4 domain
LXH20_RS00030	COG0187	DNA topoisomerase II activity
LXH20_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LXH20_RS00070	COG0516	GMP reductase activity
LXH20_RS00070	COG0517	IMP dehydrogenase activity
LXH20_RS00075	COG1686	Belongs to the peptidase S11 family
LXH20_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
LXH20_RS00105	COG1428	Deoxynucleoside kinase
LXH20_RS00110	COG1428	Deoxynucleoside kinase
LXH20_RS00115	COG1388	LysM domain
LXH20_RS00115	COG3858	chitin binding
LXH20_RS00120	COG1335	isochorismatase
LXH20_RS00125	COG0590	tRNA wobble adenosine to inosine editing
LXH20_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LXH20_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LXH20_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
LXH20_RS00195	COG3853	Toxic anion resistance protein (TelA)
LXH20_RS00200	COG1982	Orn Lys Arg decarboxylase major
LXH20_RS00210	COG3870	Protein conserved in bacteria
LXH20_RS00215	COG1728	Protein conserved in bacteria
LXH20_RS00220	COG0470	DNA polymerase III
LXH20_RS00225	COG1774	PSP1 C-terminal conserved region
LXH20_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LXH20_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LXH20_RS00250	COG2002	toxin-antitoxin pair type II binding
LXH20_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXH20_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXH20_RS00260	COG0084	hydrolase, TatD family'
LXH20_RS00265	COG3583	domain protein
LXH20_RS00265	COG3584	3D domain protein
LXH20_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LXH20_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LXH20_RS00285	COG4466	Protein conserved in bacteria
LXH20_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LXH20_RS00305	COG0251	oxidation-reduction process
LXH20_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LXH20_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LXH20_RS00345	COG2002	toxin-antitoxin pair type II binding
LXH20_RS00350	COG2244	polysaccharide biosynthetic process
LXH20_RS00355	COG3956	TIGRFAM MazG family protein
LXH20_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LXH20_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LXH20_RS00380	COG1098	S1 RNA binding domain
LXH20_RS00395	COG2208	phosphoserine phosphatase activity
LXH20_RS00400	COG2304	oxidoreductase activity
LXH20_RS00405	COG0515	serine threonine protein kinase
LXH20_RS00410	COG0037	tRNA processing
LXH20_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LXH20_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LXH20_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LXH20_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LXH20_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LXH20_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
LXH20_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXH20_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LXH20_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LXH20_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LXH20_RS00475	COG1396	sequence-specific DNA binding
LXH20_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LXH20_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LXH20_RS00565	COG4463	regulation of RNA biosynthetic process
LXH20_RS00570	COG3880	PFAM UvrB UvrC protein
LXH20_RS00580	COG0542	response to heat
LXH20_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LXH20_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LXH20_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
LXH20_RS00615	COG1045	serine acetyltransferase
LXH20_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LXH20_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LXH20_RS00635	COG3688	RNA-binding protein containing a PIN domain
LXH20_RS00640	COG1595	DNA-templated transcription, initiation
LXH20_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LXH20_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
LXH20_RS00680	COG2813	Specifically methylates the guanine in position
LXH20_RS00695	COG1358	cellular component organization or biogenesis
LXH20_RS00720	COG0596	Alpha beta hydrolase
LXH20_RS00830	COG0201	protein transport
LXH20_RS00840	COG0024	Methionine aminopeptidase
LXH20_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LXH20_RS00880	COG1122	ATPase activity
LXH20_RS00885	COG1122	ATPase activity
LXH20_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LXH20_RS00910	COG2226	methyltransferase
LXH20_RS00915	COG2318	DinB family
LXH20_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
LXH20_RS00930	COG0489	protein tyrosine kinase activity
LXH20_RS00940	COG2194	sulfuric ester hydrolase activity
LXH20_RS00945	COG0726	polysaccharide deacetylase
LXH20_RS01005	COG0738	Major facilitator superfamily
LXH20_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LXH20_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
LXH20_RS01030	COG0385	Bile acid
LXH20_RS01035	COG2819	hydrolase of the alpha beta superfamily
LXH20_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXH20_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXH20_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXH20_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXH20_RS01055	COG2207	Transcriptional regulator
LXH20_RS01060	COG3876	Protein conserved in bacteria
LXH20_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
LXH20_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LXH20_RS01075	COG1263	PTS System
LXH20_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXH20_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXH20_RS01090	COG1683	Conserved Protein
LXH20_RS01120	COG1595	DNA-templated transcription, initiation
LXH20_RS01125	COG5662	AntiSigma factor
LXH20_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LXH20_RS01135	COG4856	YbbR-like protein
LXH20_RS01175	COG1346	cytolysis
LXH20_RS01180	COG1380	Effector of murein hydrolase LrgA
LXH20_RS01185	COG1846	Transcriptional regulator
LXH20_RS01190	COG1113	amino acid transport
LXH20_RS01195	COG1011	Hydrolase
LXH20_RS01200	COG4585	Histidine kinase
LXH20_RS01205	COG2197	response regulator
LXH20_RS01210	COG1131	(ABC) transporter
LXH20_RS01250	COG0531	amino acid
LXH20_RS01255	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LXH20_RS01270	COG0584	glycerophosphoryl diester phosphodiesterase
LXH20_RS01275	COG2271	Major facilitator Superfamily
LXH20_RS01285	COG2368	4-hydroxyphenylacetate
LXH20_RS01295	COG3409	Peptidoglycan-binding domain 1 protein
LXH20_RS01310	COG0371	Dehydrogenase
LXH20_RS01320	COG1183	phosphatidylcholine synthase activity
LXH20_RS01325	COG0586	Pfam SNARE associated Golgi protein
LXH20_RS01330	COG0688	phosphatidylethanolamine metabolic process
LXH20_RS01345	COG1301	dicarboxylic acid transport
LXH20_RS01350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXH20_RS01355	COG0833	amino acid
LXH20_RS01360	COG2040	homocysteine
LXH20_RS01365	COG1115	amino acid carrier protein
LXH20_RS01370	COG2066	Belongs to the glutaminase family
LXH20_RS01375	COG4191	Histidine kinase
LXH20_RS01380	COG0784	Response regulator, receiver
LXH20_RS01385	COG3173	Aminoglycoside phosphotransferase
LXH20_RS01400	COG3773	Cell wall hydrolase
LXH20_RS01405	COG3540	Alkaline phosphatase
LXH20_RS01410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LXH20_RS01415	COG0805	protein transport
LXH20_RS01425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LXH20_RS01430	COG0477	Major facilitator Superfamily
LXH20_RS01435	COG1309	transcriptional regulator
LXH20_RS01440	COG0252	asparaginase activity
LXH20_RS01445	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LXH20_RS01450	COG3012	SEC-C Motif Domain Protein
LXH20_RS01450	COG1405	negative regulation of cell septum assembly
LXH20_RS01455	COG0667	Aldo Keto reductase
LXH20_RS01465	COG1595	DNA-templated transcription, initiation
LXH20_RS01470	COG1595	DNA-templated transcription, initiation
LXH20_RS01475	COG1876	peptidase activity
LXH20_RS01480	COG0457	Tetratricopeptide repeat
LXH20_RS01485	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS01495	COG0366	Alpha amylase catalytic
LXH20_RS01500	COG0803	Belongs to the bacterial solute-binding protein 9 family
LXH20_RS01505	COG1121	(ABC) transporter
LXH20_RS01510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LXH20_RS01515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXH20_RS01520	COG2310	stress, protein
LXH20_RS01525	COG2310	stress, protein
LXH20_RS01530	COG2310	stress, protein
LXH20_RS01535	COG0861	Integral membrane protein TerC family
LXH20_RS01545	COG3853	Toxic anion resistance protein (TelA)
LXH20_RS01550	COG0477	Major facilitator Superfamily
LXH20_RS01555	COG4175	Glycine betaine
LXH20_RS01555	COG0517	IMP dehydrogenase activity
LXH20_RS01560	COG4176	ABC-type proline glycine betaine transport system permease component
LXH20_RS01565	COG2113	Glycine betaine
LXH20_RS01570	COG1473	amidohydrolase
LXH20_RS01575	COG1288	antiporter activity
LXH20_RS01585	COG0366	Alpha amylase catalytic
LXH20_RS01595	COG2814	Major facilitator Superfamily
LXH20_RS01600	COG1846	Transcriptional regulator
LXH20_RS01605	COG1280	lysine exporter protein (LysE YggA)
LXH20_RS01610	COG3403	YqcI/YcgG family
LXH20_RS01615	COG1113	amino acid transport
LXH20_RS01620	COG3665	Urea carboxylase-associated protein
LXH20_RS01635	COG1660	Displays ATPase and GTPase activities
LXH20_RS01645	COG2271	Major facilitator Superfamily
LXH20_RS01650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LXH20_RS01655	COG2226	methyltransferase
LXH20_RS01660	COG0583	DNA-binding transcription factor activity
LXH20_RS01665	COG3458	cephalosporin-C deacetylase activity
LXH20_RS01670	COG3541	Predicted nucleotidyltransferase
LXH20_RS01675	COG0506	proline dehydrogenase activity
LXH20_RS01680	COG1012	belongs to the aldehyde dehydrogenase family
LXH20_RS01685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXH20_RS01690	COG2508	Transcriptional regulator
LXH20_RS01700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LXH20_RS01700	COG1587	Uroporphyrinogen-III synthase
LXH20_RS01705	COG2146	nitrite reductase [NAD(P)H] activity
LXH20_RS01710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXH20_RS01715	COG0243	molybdopterin cofactor binding
LXH20_RS01720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXH20_RS01725	COG2223	nitrite transmembrane transporter activity
LXH20_RS01730	COG0523	cobalamin synthesis protein
LXH20_RS01735	COG1063	alcohol dehydrogenase
LXH20_RS01740	COG1714	RDD family
LXH20_RS01750	COG2723	6-phospho-beta-galactosidase activity
LXH20_RS01760	COG3209	COG3209 Rhs family protein
LXH20_RS01765	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LXH20_RS01770	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LXH20_RS01775	COG1733	regulation of RNA biosynthetic process
LXH20_RS01780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS01810	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LXH20_RS01825	COG2364	Membrane
LXH20_RS01830	COG1126	abc transporter atp-binding protein
LXH20_RS01835	COG0765	amino acid transport
LXH20_RS01840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXH20_RS01845	COG0583	DNA-binding transcription factor activity
LXH20_RS01850	COG0163	prenyltransferase activity
LXH20_RS01855	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LXH20_RS01870	COG3104	oligopeptide transport
LXH20_RS01875	COG5434	Belongs to the glycosyl hydrolase 28 family
LXH20_RS01885	COG0697	spore germination
LXH20_RS01895	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LXH20_RS01900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXH20_RS01905	COG0456	acetyltransferase
LXH20_RS01910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXH20_RS01915	COG0765	amino acid transport
LXH20_RS01920	COG1126	abc transporter atp-binding protein
LXH20_RS01925	COG1473	amidohydrolase
LXH20_RS01930	COG2079	MmgE PrpD family protein
LXH20_RS01935	COG1136	(ABC) transporter
LXH20_RS01940	COG0577	efflux transmembrane transporter activity
LXH20_RS01945	COG0745	RESPONSE REGULATOR receiver
LXH20_RS01950	COG3850	Histidine kinase
LXH20_RS01950	COG5002	protein histidine kinase activity
LXH20_RS01955	COG0457	Tetratricopeptide repeat
LXH20_RS01970	COG0527	aspartate kinase activity
LXH20_RS01975	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXH20_RS01980	COG4605	iron ion homeostasis
LXH20_RS01985	COG4604	ABC transporter, ATP-binding protein
LXH20_RS01990	COG4607	ABC-type enterochelin transport system periplasmic component
LXH20_RS01995	COG2814	Major facilitator Superfamily
LXH20_RS02000	COG1309	transcriptional regulator
LXH20_RS02005	COG0778	Nitroreductase
LXH20_RS02010	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LXH20_RS02015	COG0640	Transcriptional regulator
LXH20_RS02020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXH20_RS02025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LXH20_RS02030	COG1012	belongs to the aldehyde dehydrogenase family
LXH20_RS02035	COG4975	Glucose uptake
LXH20_RS02040	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS02045	COG4549	nuclear export factor GLE1
LXH20_RS02050	COG2372	response to copper ion
LXH20_RS02050	COG1276	copper resistance
LXH20_RS02055	COG1349	DNA-binding transcription factor activity
LXH20_RS02065	COG2213	PTS system mannitol-specific
LXH20_RS02070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXH20_RS02080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LXH20_RS02090	COG0561	phosphatase activity
LXH20_RS02100	COG1914	H( )-stimulated, divalent metal cation uptake system
LXH20_RS02110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LXH20_RS02115	COG1984	allophanate hydrolase subunit 2
LXH20_RS02120	COG1414	Transcriptional regulator
LXH20_RS02125	COG2755	lipolytic protein G-D-S-L family
LXH20_RS02135	COG2329	Antibiotic biosynthesis monooxygenase
LXH20_RS02140	COG0768	penicillin binding
LXH20_RS02145	COG4989	oxidoreductase activity
LXH20_RS02150	COG3711	transcriptional antiterminator
LXH20_RS02155	COG0318	PFAM AMP-dependent synthetase and ligase
LXH20_RS02160	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS02165	COG1917	Cupin 2, conserved barrel domain protein
LXH20_RS02170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXH20_RS02175	COG3871	stress protein (general stress protein 26)
LXH20_RS02185	COG2814	Major facilitator Superfamily
LXH20_RS02190	COG1522	sequence-specific DNA binding
LXH20_RS02195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LXH20_RS02195	COG0551	DNA topoisomerase type I activity
LXH20_RS02200	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LXH20_RS02205	COG3706	GGDEF domain
LXH20_RS02210	COG5298	Protein conserved in bacteria
LXH20_RS02215	COG1215	transferase activity, transferring glycosyl groups
LXH20_RS02225	COG0531	amino acid
LXH20_RS02230	COG0494	nUDIX hydrolase
LXH20_RS02235	COG0028	Belongs to the TPP enzyme family
LXH20_RS02250	COG4282	regulation of fungal-type cell wall biogenesis
LXH20_RS02290	COG1914	H( )-stimulated, divalent metal cation uptake system
LXH20_RS02310	COG2076	Multidrug Resistance protein
LXH20_RS02315	COG2217	Heavy metal translocating P-type atpase
LXH20_RS02325	COG0662	Cupin 2, conserved barrel domain protein
LXH20_RS02330	COG2329	Antibiotic biosynthesis monooxygenase
LXH20_RS02335	COG3546	catalase activity
LXH20_RS02340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LXH20_RS02345	COG3290	protein histidine kinase activity
LXH20_RS02350	COG4565	transcriptional regulatory protein
LXH20_RS02355	COG1301	dicarboxylic acid transport
LXH20_RS02360	COG0628	permease
LXH20_RS02365	COG1131	(ABC) transporter
LXH20_RS02370	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LXH20_RS02380	COG1960	acyl-CoA dehydrogenase activity
LXH20_RS02395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LXH20_RS02400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXH20_RS02410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LXH20_RS02415	COG0513	Belongs to the DEAD box helicase family
LXH20_RS02420	COG3402	PFAM membrane-flanked domain
LXH20_RS02425	COG3428	Bacterial PH domain
LXH20_RS02430	COG0705	Rhomboid family
LXH20_RS02440	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LXH20_RS02445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LXH20_RS02450	COG0864	Transcriptional regulator
LXH20_RS02455	COG2337	Toxic component of a toxin-antitoxin (TA) module
LXH20_RS02460	COG1366	Belongs to the anti-sigma-factor antagonist family
LXH20_RS02465	COG1366	Belongs to the anti-sigma-factor antagonist family
LXH20_RS02470	COG2172	sigma factor antagonist activity
LXH20_RS02475	COG2208	phosphoserine phosphatase activity
LXH20_RS02480	COG1366	Belongs to the anti-sigma-factor antagonist family
LXH20_RS02490	COG1191	sigma factor activity
LXH20_RS02495	COG2208	phosphoserine phosphatase activity
LXH20_RS02500	COG2183	response to ionizing radiation
LXH20_RS02565	COG0477	Major facilitator Superfamily
LXH20_RS02575	COG2030	dehydratase
LXH20_RS02590	COG1959	2 iron, 2 sulfur cluster binding
LXH20_RS02595	COG2910	NAD(P)H-binding
LXH20_RS02605	COG1309	transcriptional regulator
LXH20_RS02610	COG3239	Fatty acid desaturase
LXH20_RS02615	COG1278	Cold shock
LXH20_RS02620	COG1329	Transcriptional regulator
LXH20_RS02625	COG1937	Protein conserved in bacteria
LXH20_RS02630	COG2210	Belongs to the sulfur carrier protein TusA family
LXH20_RS02635	COG1054	Belongs to the UPF0176 family
LXH20_RS02640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LXH20_RS02640	COG0425	Belongs to the sulfur carrier protein TusA family
LXH20_RS02650	COG0425	Belongs to the sulfur carrier protein TusA family
LXH20_RS02655	COG0730	response to heat
LXH20_RS02660	COG1794	racemase activity, acting on amino acids and derivatives
LXH20_RS02675	COG3621	Patatin-like phospholipase
LXH20_RS02685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LXH20_RS02690	COG1802	Transcriptional regulator
LXH20_RS02695	COG0251	oxidation-reduction process
LXH20_RS02700	COG0814	amino acid
LXH20_RS02705	COG1473	amidohydrolase
LXH20_RS02710	COG1917	Cupin 2, conserved barrel domain protein
LXH20_RS02710	COG2207	Transcriptional regulator
LXH20_RS02720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXH20_RS02725	COG0477	Major facilitator Superfamily
LXH20_RS02745	COG0277	FAD linked oxidase domain protein
LXH20_RS02765	COG0662	Cupin 2, conserved barrel domain protein
LXH20_RS02770	COG2318	DinB family
LXH20_RS02775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LXH20_RS02800	COG1064	alcohol dehydrogenase
LXH20_RS02805	COG0789	Transcriptional regulator
LXH20_RS02815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXH20_RS02830	COG2814	Major facilitator Superfamily
LXH20_RS02835	COG1309	transcriptional regulator
LXH20_RS02840	COG0697	spore germination
LXH20_RS02845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXH20_RS02850	COG5577	PFAM Coat F domain
LXH20_RS02860	COG1063	alcohol dehydrogenase
LXH20_RS02865	COG5577	PFAM Coat F domain
LXH20_RS02875	COG0738	Major facilitator superfamily
LXH20_RS02900	COG4585	Histidine kinase
LXH20_RS02905	COG2197	response regulator
LXH20_RS02910	COG2409	Drug exporters of the RND superfamily
LXH20_RS02915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LXH20_RS02920	COG0488	(ABC) transporter
LXH20_RS02925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXH20_RS02930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXH20_RS02940	COG2814	Major facilitator Superfamily
LXH20_RS02945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LXH20_RS02955	COG0730	response to heat
LXH20_RS02960	COG0456	acetyltransferase
LXH20_RS02965	COG4978	Transcriptional regulator
LXH20_RS02965	COG0789	Transcriptional regulator
LXH20_RS02970	COG0697	spore germination
LXH20_RS02975	COG1051	belongs to the nudix hydrolase family
LXH20_RS02980	COG2226	methyltransferase
LXH20_RS02985	COG0473	3-isopropylmalate dehydrogenase activity
LXH20_RS02990	COG1802	Transcriptional regulator
LXH20_RS02995	COG1819	glycosyl
LXH20_RS03010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LXH20_RS03020	COG1388	LysM domain
LXH20_RS03025	COG2814	Major facilitator Superfamily
LXH20_RS03030	COG2188	Transcriptional regulator
LXH20_RS03035	COG2186	Transcriptional regulator
LXH20_RS03040	COG2807	transmembrane transport
LXH20_RS03045	COG2076	Multidrug Resistance protein
LXH20_RS03050	COG2076	Multidrug Resistance protein
LXH20_RS03055	COG1309	transcriptional regulator
LXH20_RS03060	COG0531	amino acid
LXH20_RS03070	COG3832	glyoxalase III activity
LXH20_RS03075	COG0604	alcohol dehydrogenase
LXH20_RS03080	COG2814	Major facilitator Superfamily
LXH20_RS03120	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LXH20_RS03125	COG0802	atpase or kinase
LXH20_RS03130	COG1214	PFAM Peptidase M22, glycoprotease
LXH20_RS03135	COG0456	acetyltransferase
LXH20_RS03140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LXH20_RS03145	COG0488	(ABC) transporter
LXH20_RS03160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LXH20_RS03165	COG0805	protein transport
LXH20_RS03175	COG1266	CAAX protease self-immunity
LXH20_RS03190	COG3409	Peptidoglycan-binding domain 1 protein
LXH20_RS03205	COG0457	Tetratricopeptide repeat
LXH20_RS03210	COG1063	alcohol dehydrogenase
LXH20_RS03215	COG2211	Major facilitator Superfamily
LXH20_RS03220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXH20_RS03230	COG1842	Phage shock protein A
LXH20_RS03235	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LXH20_RS03240	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LXH20_RS03245	COG4260	virion core protein, lumpy skin disease virus
LXH20_RS03250	COG2755	lipolytic protein G-D-S-L family
LXH20_RS03250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LXH20_RS03260	COG1595	DNA-templated transcription, initiation
LXH20_RS03265	COG1063	alcohol dehydrogenase
LXH20_RS03270	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LXH20_RS03275	COG0823	Involved in the tonB-independent uptake of proteins
LXH20_RS03290	COG2132	Multicopper oxidase
LXH20_RS03295	COG1113	amino acid transport
LXH20_RS03300	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LXH20_RS03305	COG0714	Associated with various cellular activities
LXH20_RS03310	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LXH20_RS03315	COG1305	Transglutaminase-like
LXH20_RS03325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LXH20_RS03345	COG2211	Major facilitator Superfamily
LXH20_RS03360	COG2252	PERMEase
LXH20_RS03365	COG3064	Membrane
LXH20_RS03385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LXH20_RS03390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LXH20_RS03395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LXH20_RS03400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LXH20_RS03405	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LXH20_RS03420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LXH20_RS03430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LXH20_RS03435	COG0138	bifunctional purine biosynthesis protein purh
LXH20_RS03440	COG0151	Belongs to the GarS family
LXH20_RS03450	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LXH20_RS03455	COG1470	cell adhesion involved in biofilm formation
LXH20_RS03460	COG4496	protein, YerC YecD
LXH20_RS03465	COG0069	glutamate synthase activity
LXH20_RS03475	COG0210	DNA helicase
LXH20_RS03485	COG4851	CamS sex pheromone cAM373 precursor
LXH20_RS03490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LXH20_RS03495	COG1285	pathogenesis
LXH20_RS03500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXH20_RS03520	COG1309	transcriptional regulator
LXH20_RS03525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LXH20_RS03530	COG1597	lipid kinase activity
LXH20_RS03535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LXH20_RS03595	COG5444	nuclease activity
LXH20_RS03625	COG3546	catalase activity
LXH20_RS03630	COG0454	-acetyltransferase
LXH20_RS03640	COG2323	membrane
LXH20_RS03645	COG2329	Antibiotic biosynthesis monooxygenase
LXH20_RS03650	COG0346	lactoylglutathione lyase activity
LXH20_RS03655	COG1366	Belongs to the anti-sigma-factor antagonist family
LXH20_RS03660	COG5583	Uncharacterized small protein (DUF2292)
LXH20_RS03665	COG0196	riboflavin kinase activity
LXH20_RS03670	COG0670	Belongs to the BI1 family
LXH20_RS03675	COG1846	Transcriptional regulator
LXH20_RS03680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXH20_RS03690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LXH20_RS03690	COG2124	cytochrome p450
LXH20_RS03705	COG1131	(ABC) transporter
LXH20_RS03715	COG1368	sulfuric ester hydrolase activity
LXH20_RS03720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LXH20_RS03725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXH20_RS03730	COG1442	glycosyl transferase family 8
LXH20_RS03735	COG1216	Glycosyl transferase, family 2
LXH20_RS03740	COG1442	glycosyl transferase family 8
LXH20_RS03745	COG2223	nitrite transmembrane transporter activity
LXH20_RS03750	COG0531	amino acid
LXH20_RS03755	COG1012	belongs to the aldehyde dehydrogenase family
LXH20_RS03760	COG0840	transmembrane signaling receptor activity
LXH20_RS03765	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS03770	COG0463	Glycosyl transferase, family 2
LXH20_RS03775	COG0488	(ABC) transporter
LXH20_RS03780	COG0789	Transcriptional regulator
LXH20_RS03785	COG2814	Major facilitator Superfamily
LXH20_RS03790	COG0488	(ABC) transporter
LXH20_RS03795	COG0513	Belongs to the DEAD box helicase family
LXH20_RS03800	COG0456	acetyltransferase
LXH20_RS03805	COG2130	NADP-dependent
LXH20_RS03820	COG3866	Pectate lyase
LXH20_RS03825	COG0471	metal ion transport
LXH20_RS03845	COG0745	RESPONSE REGULATOR receiver
LXH20_RS03845	COG2972	Histidine kinase
LXH20_RS03855	COG3279	Response regulator of the LytR AlgR family
LXH20_RS03865	COG3764	Sortase (surface protein transpeptidase)
LXH20_RS03870	COG3290	protein histidine kinase activity
LXH20_RS03875	COG4565	transcriptional regulatory protein
LXH20_RS03880	COG3181	Tripartite tricarboxylate transporter family receptor
LXH20_RS03885	COG2851	Citrate transporter
LXH20_RS03890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXH20_RS03895	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LXH20_RS03905	COG2258	MOSC domain
LXH20_RS03925	COG0024	Methionine aminopeptidase
LXH20_RS03930	COG1263	PTS System
LXH20_RS03930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXH20_RS03940	COG1368	sulfuric ester hydrolase activity
LXH20_RS03950	COG0071	Belongs to the small heat shock protein (HSP20) family
LXH20_RS03965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXH20_RS03965	COG1263	PTS System
LXH20_RS03970	COG0366	Alpha amylase catalytic
LXH20_RS03975	COG2188	Transcriptional regulator
LXH20_RS03980	COG0778	Nitroreductase
LXH20_RS03995	COG0737	Belongs to the 5'-nucleotidase family
LXH20_RS04000	COG0693	protein deglycase activity
LXH20_RS04005	COG1609	Transcriptional regulator
LXH20_RS04020	COG2814	Major facilitator Superfamily
LXH20_RS04030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LXH20_RS04035	COG4980	gas vesicle protein
LXH20_RS04040	COG1295	ribonuclease BN
LXH20_RS04050	COG0477	Major facilitator Superfamily
LXH20_RS04055	COG0387	Pfam Sodium calcium exchanger
LXH20_RS04065	COG0668	transmembrane transport
LXH20_RS04070	COG0535	radical SAM domain protein
LXH20_RS04080	COG0726	polysaccharide deacetylase
LXH20_RS04100	COG0745	RESPONSE REGULATOR receiver
LXH20_RS04105	COG2205	protein histidine kinase activity
LXH20_RS04110	COG2084	Dehydrogenase
LXH20_RS04120	COG0598	Magnesium transport protein CorA
LXH20_RS04125	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LXH20_RS04130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LXH20_RS04145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LXH20_RS04150	COG4637	Psort location Cytoplasmic, score
LXH20_RS04155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LXH20_RS04160	COG0022	dehydrogenase e1 component
LXH20_RS04165	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXH20_RS04170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXH20_RS04175	COG3284	Transcriptional regulator
LXH20_RS04185	COG1486	melibiose metabolic process
LXH20_RS04190	COG1737	Transcriptional regulator
LXH20_RS04195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXH20_RS04195	COG1263	PTS System
LXH20_RS04200	COG1132	(ABC) transporter
LXH20_RS04205	COG1132	(ABC) transporter
LXH20_RS04210	COG2259	Doxx family
LXH20_RS04215	COG2514	catechol 2,3-dioxygenase activity
LXH20_RS04225	COG1695	Transcriptional regulator
LXH20_RS04230	COG2249	NAD(P)H dehydrogenase (quinone) activity
LXH20_RS04235	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LXH20_RS04240	COG3848	Pyruvate phosphate dikinase
LXH20_RS04240	COG0574	Belongs to the PEP-utilizing enzyme family
LXH20_RS04245	COG2732	(Barnase) inhibitor
LXH20_RS04250	COG2318	DinB family
LXH20_RS04255	COG2814	Major facilitator Superfamily
LXH20_RS04260	COG1846	Transcriptional regulator
LXH20_RS04265	COG0392	lysyltransferase activity
LXH20_RS04265	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LXH20_RS04270	COG0384	phenazine biosynthesis protein PhzF
LXH20_RS04275	COG0778	Nitroreductase
LXH20_RS04290	COG1090	epimerase
LXH20_RS04305	COG2814	Major facilitator Superfamily
LXH20_RS04315	COG3591	Belongs to the peptidase S1B family
LXH20_RS04330	COG3103	Sh3 type 3 domain protein
LXH20_RS04335	COG5658	integral membrane protein
LXH20_RS04340	COG0596	Alpha beta hydrolase
LXH20_RS04345	COG0463	Glycosyl transferase, family 2
LXH20_RS04350	COG4485	Bacterial membrane protein, YfhO
LXH20_RS04355	COG1988	membrane-bound metal-dependent
LXH20_RS04360	COG1194	a g-specific adenine glycosylase
LXH20_RS04370	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS04390	COG1132	(ABC) transporter
LXH20_RS04395	COG4129	membrane
LXH20_RS04405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LXH20_RS04410	COG0735	belongs to the Fur family
LXH20_RS04525	COG3340	Belongs to the peptidase S51 family
LXH20_RS04535	COG0277	FAD linked oxidase domain protein
LXH20_RS04545	COG0747	negative chemotaxis
LXH20_RS04550	COG0601	transmembrane transport
LXH20_RS04555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXH20_RS04560	COG0444	Belongs to the ABC transporter superfamily
LXH20_RS04565	COG4608	Belongs to the ABC transporter superfamily
LXH20_RS04570	COG0753	catalase activity
LXH20_RS04580	COG1116	anion transmembrane transporter activity
LXH20_RS04585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXH20_RS04590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXH20_RS04610	COG1476	TRANSCRIPTIONal
LXH20_RS04620	COG3382	B3 4 domain protein
LXH20_RS04625	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LXH20_RS04635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LXH20_RS04640	COG0789	Transcriptional regulator
LXH20_RS04645	COG1664	Polymer-forming cytoskeletal
LXH20_RS04650	COG1664	Polymer-forming cytoskeletal
LXH20_RS04655	COG2766	serine protein kinase
LXH20_RS04665	COG1846	Transcriptional regulator
LXH20_RS04670	COG1566	PFAM secretion protein HlyD family protein
LXH20_RS04675	COG2814	Major facilitator Superfamily
LXH20_RS04680	COG0655	NAD(P)H dehydrogenase (quinone) activity
LXH20_RS04695	COG1725	Transcriptional regulator
LXH20_RS04700	COG1131	(ABC) transporter
LXH20_RS04705	COG1131	(ABC) transporter
LXH20_RS04710	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LXH20_RS04715	COG1278	Cold shock
LXH20_RS04720	COG1464	Belongs to the NlpA lipoprotein family
LXH20_RS04725	COG3706	GGDEF domain
LXH20_RS04730	COG1823	symporter activity
LXH20_RS04750	COG5577	PFAM Coat F domain
LXH20_RS04755	COG0737	Belongs to the 5'-nucleotidase family
LXH20_RS04755	COG1525	nuclease
LXH20_RS04755	COG4085	toxin activity
LXH20_RS04760	COG3764	Sortase (surface protein transpeptidase)
LXH20_RS04765	COG0564	pseudouridine synthase activity
LXH20_RS04775	COG0517	IMP dehydrogenase activity
LXH20_RS04780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LXH20_RS04785	COG3153	acetyltransferase
LXH20_RS04785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LXH20_RS04790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LXH20_RS04795	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LXH20_RS04800	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LXH20_RS04810	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LXH20_RS04815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LXH20_RS04820	COG4585	Histidine kinase
LXH20_RS04820	COG2203	Gaf domain
LXH20_RS04825	COG2197	response regulator
LXH20_RS04830	COG0431	NADPH-dependent FMN reductase
LXH20_RS04845	COG0791	NLP P60 protein
LXH20_RS04845	COG1388	LysM domain
LXH20_RS04850	COG1959	2 iron, 2 sulfur cluster binding
LXH20_RS04860	COG2719	SpoVR family
LXH20_RS04865	COG1785	Belongs to the alkaline phosphatase family
LXH20_RS04870	COG0791	NLP P60 protein
LXH20_RS04870	COG1388	LysM domain
LXH20_RS04875	COG0583	DNA-binding transcription factor activity
LXH20_RS04880	COG0372	Belongs to the citrate synthase family
LXH20_RS04885	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS04890	COG0531	amino acid
LXH20_RS04895	COG0733	neurotransmitter:sodium symporter activity
LXH20_RS04910	COG1595	DNA-templated transcription, initiation
LXH20_RS04915	COG0204	Acyl-transferase
LXH20_RS04920	COG1253	flavin adenine dinucleotide binding
LXH20_RS04925	COG0789	Transcriptional regulator
LXH20_RS04930	COG0436	Aminotransferase
LXH20_RS04935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LXH20_RS04940	COG1253	flavin adenine dinucleotide binding
LXH20_RS04945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LXH20_RS04950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LXH20_RS04955	COG0584	glycerophosphoryl diester phosphodiesterase
LXH20_RS04965	COG0668	transmembrane transport
LXH20_RS04970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LXH20_RS04975	COG0726	polysaccharide deacetylase
LXH20_RS04980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXH20_RS04985	COG3226	Transcriptional regulator
LXH20_RS04995	COG0589	response to stress
LXH20_RS05000	COG1132	(ABC) transporter
LXH20_RS05005	COG1132	(ABC) transporter
LXH20_RS05010	COG0702	epimerase
LXH20_RS05030	COG0189	ligase activity
LXH20_RS05035	COG0189	ligase activity
LXH20_RS05050	COG4335	DNA alkylation repair
LXH20_RS05055	COG0561	phosphatase activity
LXH20_RS05060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LXH20_RS05070	COG0475	glutathione-regulated potassium exporter activity
LXH20_RS05075	COG0490	domain, Protein
LXH20_RS05085	COG1024	Enoyl-CoA hydratase
LXH20_RS05095	COG4152	abc transporter atp-binding protein
LXH20_RS05100	COG1668	transmembrane transport
LXH20_RS05105	COG0420	3'-5' exonuclease activity
LXH20_RS05110	COG4717	serine-type aminopeptidase activity
LXH20_RS05125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LXH20_RS05160	COG4980	gas vesicle protein
LXH20_RS05175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LXH20_RS05180	COG0537	adenosine 5'-monophosphoramidase activity
LXH20_RS05185	COG1131	(ABC) transporter
LXH20_RS05190	COG4473	ABC transporter
LXH20_RS05200	COG1473	amidohydrolase
LXH20_RS05205	COG3069	C4-dicarboxylate transmembrane transporter activity
LXH20_RS05210	COG2329	Antibiotic biosynthesis monooxygenase
LXH20_RS05215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXH20_RS05225	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LXH20_RS05230	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LXH20_RS05235	COG1309	transcriptional regulator
LXH20_RS05240	COG1511	domain protein
LXH20_RS05245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LXH20_RS05255	COG1363	Peptidase, m42
LXH20_RS05260	COG1301	dicarboxylic acid transport
LXH20_RS05270	COG1234	tRNA 3'-trailer cleavage
LXH20_RS05275	COG0095	Lipoate-protein ligase
LXH20_RS05280	COG0702	epimerase
LXH20_RS05285	COG0318	PFAM AMP-dependent synthetase and ligase
LXH20_RS05295	COG0501	Belongs to the peptidase M48B family
LXH20_RS05300	COG1404	Belongs to the peptidase S8 family
LXH20_RS05305	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LXH20_RS05310	COG0406	alpha-ribazole phosphatase activity
LXH20_RS05315	COG0183	Belongs to the thiolase family
LXH20_RS05320	COG0318	PFAM AMP-dependent synthetase and ligase
LXH20_RS05325	COG1268	BioY protein
LXH20_RS05330	COG0840	transmembrane signaling receptor activity
LXH20_RS05335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LXH20_RS05335	COG0723	plastoquinol--plastocyanin reductase activity
LXH20_RS05340	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS05350	COG4903	ComK protein
LXH20_RS05355	COG5646	InterPro IPR014922
LXH20_RS05360	COG5646	InterPro IPR014922
LXH20_RS05385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXH20_RS05400	COG0398	Pfam SNARE associated Golgi protein
LXH20_RS05405	COG0681	Belongs to the peptidase S26 family
LXH20_RS05410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXH20_RS05415	COG1846	Transcriptional regulator
LXH20_RS05420	COG3180	Ammonia monooxygenase
LXH20_RS05425	COG2814	Major facilitator Superfamily
LXH20_RS05435	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LXH20_RS05440	COG2323	membrane
LXH20_RS05455	COG0420	3'-5' exonuclease activity
LXH20_RS05460	COG0419	ATPase involved in DNA repair
LXH20_RS05465	COG1403	HNH endonuclease
LXH20_RS05505	COG0179	Fumarylacetoacetate (FAA) hydrolase
LXH20_RS05520	COG0367	asparagine synthase
LXH20_RS05525	COG1562	ergosterol biosynthetic process
LXH20_RS05530	COG0534	Mate efflux family protein
LXH20_RS05535	COG1917	Cupin 2, conserved barrel domain protein
LXH20_RS05535	COG2207	Transcriptional regulator
LXH20_RS05540	COG1609	Transcriptional regulator
LXH20_RS05545	COG0673	inositol 2-dehydrogenase activity
LXH20_RS05550	COG2318	DinB family
LXH20_RS05555	COG1357	PFAM Pentapeptide repeats (8 copies)
LXH20_RS05560	COG2153	protein acetylation
LXH20_RS05565	COG0646	methionine synthase
LXH20_RS05565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LXH20_RS05575	COG2996	Protein conserved in bacteria
LXH20_RS05580	COG1744	ABC transporter substrate-binding protein PnrA-like
LXH20_RS05585	COG0840	transmembrane signaling receptor activity
LXH20_RS05590	COG2124	cytochrome p450
LXH20_RS05600	COG1307	EDD domain protein, DegV family
LXH20_RS05605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXH20_RS05625	COG0561	phosphatase activity
LXH20_RS05630	COG1073	alpha beta
LXH20_RS05635	COG2151	metal-sulfur cluster biosynthetic enzyme
LXH20_RS05645	COG0277	FAD linked oxidase domain protein
LXH20_RS05650	COG2271	Major facilitator Superfamily
LXH20_RS05660	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LXH20_RS05670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LXH20_RS05675	COG0505	Belongs to the CarA family
LXH20_RS05680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LXH20_RS05685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LXH20_RS05700	COG2267	carboxylic ester hydrolase activity
LXH20_RS05710	COG1744	ABC transporter substrate-binding protein PnrA-like
LXH20_RS05725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LXH20_RS05730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LXH20_RS05735	COG5504	Zn-dependent protease
LXH20_RS05740	COG0444	Belongs to the ABC transporter superfamily
LXH20_RS05745	COG4608	Belongs to the ABC transporter superfamily
LXH20_RS05755	COG0601	transmembrane transport
LXH20_RS05760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXH20_RS05770	COG0180	Tryptophanyl-tRNA synthetase
LXH20_RS05775	COG4166	transmembrane transport
LXH20_RS05780	COG0601	transmembrane transport
LXH20_RS05785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXH20_RS05790	COG0444	Belongs to the ABC transporter superfamily
LXH20_RS05795	COG4608	Belongs to the ABC transporter superfamily
LXH20_RS05805	COG0456	acetyltransferase
LXH20_RS05810	COG1393	Belongs to the ArsC family
LXH20_RS05815	COG0861	Integral membrane protein TerC family
LXH20_RS05820	COG4862	establishment of competence for transformation
LXH20_RS05825	COG4469	Competence protein
LXH20_RS05830	COG1164	Oligoendopeptidase f
LXH20_RS05840	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LXH20_RS05845	COG2346	COG2346, Truncated hemoglobins
LXH20_RS05850	COG0741	lytic transglycosylase activity
LXH20_RS05855	COG4116	CYTH
LXH20_RS05865	COG2357	RelA SpoT domain protein
LXH20_RS05870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LXH20_RS05875	COG0564	pseudouridine synthase activity
LXH20_RS05885	COG0475	glutathione-regulated potassium exporter activity
LXH20_RS05885	COG0569	domain protein
LXH20_RS05890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LXH20_RS05895	COG0352	thiamine-phosphate diphosphorylase activity
LXH20_RS05900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LXH20_RS05905	COG2104	thiamine diphosphate biosynthetic process
LXH20_RS05915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LXH20_RS05920	COG0351	phosphomethylpyrimidine kinase
LXH20_RS05925	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LXH20_RS05980	COG0210	DNA helicase
LXH20_RS06000	COG1131	(ABC) transporter
LXH20_RS06010	COG2153	protein acetylation
LXH20_RS06020	COG2382	esterase
LXH20_RS06025	COG0626	cystathionine gamma-synthase activity
LXH20_RS06030	COG0626	cystathionine gamma-synthase activity
LXH20_RS06065	COG0135	phosphoribosylanthranilate isomerase activity
LXH20_RS06090	COG1595	DNA-templated transcription, initiation
LXH20_RS06115	COG2367	Beta-lactamase
LXH20_RS06120	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LXH20_RS06125	COG0477	Major facilitator Superfamily
LXH20_RS06130	COG1846	Transcriptional regulator
LXH20_RS06140	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LXH20_RS06145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LXH20_RS06150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LXH20_RS06155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXH20_RS06155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXH20_RS06160	COG1447	Phosphotransferase system cellobiose-specific component IIA
LXH20_RS06190	COG1285	pathogenesis
LXH20_RS06200	COG2205	protein histidine kinase activity
LXH20_RS06210	COG3383	formate dehydrogenase (NAD+) activity
LXH20_RS06215	COG2427	Protein of unknown function (DUF1641)
LXH20_RS06220	COG2124	cytochrome p450
LXH20_RS06225	COG1819	glycosyl
LXH20_RS06235	COG1587	Uroporphyrinogen-III synthase
LXH20_RS06240	COG0390	transport system, permease component
LXH20_RS06245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LXH20_RS06250	COG0697	spore germination
LXH20_RS06255	COG4297	protein containing double-stranded beta helix domain
LXH20_RS06265	COG1252	NADH dehydrogenase
LXH20_RS06275	COG2211	Major facilitator Superfamily
LXH20_RS06280	COG1609	Transcriptional regulator
LXH20_RS06285	COG0246	Mannitol dehydrogenase
LXH20_RS06290	COG2721	sulfolactate sulfo-lyase activity
LXH20_RS06295	COG0730	response to heat
LXH20_RS06300	COG2318	DinB family
LXH20_RS06305	COG0457	Tetratricopeptide repeat
LXH20_RS06315	COG3409	Peptidoglycan-binding domain 1 protein
LXH20_RS06315	COG1388	LysM domain
LXH20_RS06315	COG5632	N-Acetylmuramoyl-L-alanine amidase
LXH20_RS06325	COG4195	phage-related replication protein
LXH20_RS06330	COG2856	Zn peptidase
LXH20_RS06335	COG1396	sequence-specific DNA binding
LXH20_RS06345	COG1522	sequence-specific DNA binding
LXH20_RS06350	COG1484	DNA-dependent DNA replication
LXH20_RS06370	COG1595	DNA-templated transcription, initiation
LXH20_RS06375	COG3728	DNA packaging
LXH20_RS06375	COG5484	DNA packaging
LXH20_RS06380	COG1783	phage Terminase large subunit
LXH20_RS06385	COG5518	Phage portal protein
LXH20_RS06390	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LXH20_RS06395	COG4653	Phage capsid family
LXH20_RS06445	COG5412	phage tail tape measure protein
LXH20_RS06445	COG3953	SLT domain
LXH20_RS06445	COG5412	phage tail tape measure protein
LXH20_RS06445	COG5412	phage tail tape measure protein
LXH20_RS06445	COG3953	SLT domain
LXH20_RS06445	COG3953	SLT domain
LXH20_RS06450	COG1652	LysM domain
LXH20_RS06455	COG4193	domain, Protein
LXH20_RS06465	COG3628	GPW Gp25 family protein
LXH20_RS06470	COG3299	homolog of phage Mu protein gp47
LXH20_RS06475	COG3778	Protein conserved in bacteria
LXH20_RS06515	COG3409	Peptidoglycan-binding domain 1 protein
LXH20_RS06515	COG5632	N-Acetylmuramoyl-L-alanine amidase
LXH20_RS06535	COG0306	phosphate transporter
LXH20_RS06540	COG1392	Phosphate transport regulator
LXH20_RS06545	COG0531	amino acid
LXH20_RS06550	COG0346	lactoylglutathione lyase activity
LXH20_RS06555	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LXH20_RS06560	COG0463	Glycosyl transferase, family 2
LXH20_RS06570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXH20_RS06575	COG0477	Major facilitator Superfamily
LXH20_RS06580	COG2362	D-Aminopeptidase
LXH20_RS06585	COG0601	transmembrane transport
LXH20_RS06590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXH20_RS06595	COG0444	Belongs to the ABC transporter superfamily
LXH20_RS06600	COG4166	transmembrane transport
LXH20_RS06605	COG1619	proteins homologs of microcin C7 resistance protein MccF
LXH20_RS06610	COG4948	Mandelate Racemase Muconate Lactonizing
LXH20_RS06615	COG0791	NLP P60 protein
LXH20_RS06620	COG4608	Belongs to the ABC transporter superfamily
LXH20_RS06625	COG2706	6-phosphogluconolactonase activity
LXH20_RS06630	COG1834	amidinotransferase
LXH20_RS06635	COG1607	acyl-coa hydrolase
LXH20_RS06640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXH20_RS06645	COG2076	Multidrug Resistance protein
LXH20_RS06650	COG2076	Multidrug Resistance protein
LXH20_RS06655	COG0788	formyltetrahydrofolate deformylase activity
LXH20_RS06660	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LXH20_RS06670	COG1764	response to oxidative stress
LXH20_RS06675	COG1846	Transcriptional regulator
LXH20_RS06680	COG1764	response to oxidative stress
LXH20_RS06695	COG0457	Tetratricopeptide repeat
LXH20_RS06695	COG0463	Glycosyl transferase, family 2
LXH20_RS06705	COG2814	Major facilitator Superfamily
LXH20_RS06720	COG1404	Belongs to the peptidase S8 family
LXH20_RS06725	COG1366	Belongs to the anti-sigma-factor antagonist family
LXH20_RS06730	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LXH20_RS06735	COG1122	ATPase activity
LXH20_RS06740	COG4721	ABC-type cobalt transport system, permease component
LXH20_RS06745	COG1388	LysM domain
LXH20_RS06745	COG3858	chitin binding
LXH20_RS06755	COG2239	Acts as a magnesium transporter
LXH20_RS06760	COG0789	Transcriptional regulator
LXH20_RS06775	COG1846	Transcriptional regulator
LXH20_RS06780	COG0726	polysaccharide deacetylase
LXH20_RS06785	COG1793	dna ligase
LXH20_RS06785	COG3285	dna ligase
LXH20_RS06790	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LXH20_RS06795	COG0586	Pfam SNARE associated Golgi protein
LXH20_RS06805	COG1191	sigma factor activity
LXH20_RS06830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LXH20_RS06835	COG2323	membrane
LXH20_RS06845	COG3594	Acyltransferase
LXH20_RS06850	COG5002	protein histidine kinase activity
LXH20_RS06855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LXH20_RS06875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LXH20_RS06880	COG0436	Aminotransferase
LXH20_RS06910	COG3852	Histidine kinase
LXH20_RS06915	COG1846	Transcriptional regulator
LXH20_RS06920	COG1360	Flagellar Motor Protein
LXH20_RS06925	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LXH20_RS06930	COG0542	response to heat
LXH20_RS06935	COG3949	Membrane
LXH20_RS06950	COG0720	synthase
LXH20_RS06955	COG0602	queuosine metabolic process
LXH20_RS06960	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LXH20_RS06965	COG1733	regulation of RNA biosynthetic process
LXH20_RS06970	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS06985	COG4873	Protein conserved in bacteria
LXH20_RS06995	COG3773	Cell wall hydrolase
LXH20_RS07000	COG2244	polysaccharide biosynthetic process
LXH20_RS07005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXH20_RS07010	COG2217	Heavy metal translocating P-type atpase
LXH20_RS07015	COG0006	proline dipeptidase activity
LXH20_RS07020	COG1609	Transcriptional regulator
LXH20_RS07025	COG3711	transcriptional antiterminator
LXH20_RS07030	COG1263	PTS System
LXH20_RS07030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXH20_RS07030	COG2190	(PTS) system
LXH20_RS07035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXH20_RS07040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LXH20_RS07050	COG1533	DNA photolyase activity
LXH20_RS07055	COG0840	transmembrane signaling receptor activity
LXH20_RS07060	COG2084	Dehydrogenase
LXH20_RS07075	COG2340	Cysteine-rich secretory protein family
LXH20_RS07080	COG0768	penicillin binding
LXH20_RS07085	COG4191	Histidine kinase
LXH20_RS07090	COG0436	Aminotransferase
LXH20_RS07100	COG0784	Response regulator, receiver
LXH20_RS07100	COG0835	chemotaxis
LXH20_RS07110	COG2814	Major facilitator Superfamily
LXH20_RS07115	COG1376	ErfK ybiS ycfS ynhG family protein
LXH20_RS07120	COG1408	metallophosphoesterase
LXH20_RS07125	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS07135	COG2200	EAL domain
LXH20_RS07140	COG4703	Protein of unknown function (DUF1797)
LXH20_RS07145	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LXH20_RS07155	COG0517	IMP dehydrogenase activity
LXH20_RS07160	COG0583	DNA-binding transcription factor activity
LXH20_RS07165	COG0716	FMN binding
LXH20_RS07175	COG0716	FMN binding
LXH20_RS07195	COG0668	transmembrane transport
LXH20_RS07200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXH20_RS07220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LXH20_RS07225	COG0303	'Molybdopterin
LXH20_RS07230	COG1763	Mo-molybdopterin cofactor biosynthetic process
LXH20_RS07235	COG0314	molybdopterin synthase activity
LXH20_RS07240	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LXH20_RS07250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXH20_RS07255	COG1136	(ABC) transporter
LXH20_RS07260	COG0577	efflux transmembrane transporter activity
LXH20_RS07265	COG1349	DNA-binding transcription factor activity
LXH20_RS07270	COG1105	Belongs to the carbohydrate kinase PfkB family
LXH20_RS07275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXH20_RS07275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXH20_RS07275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXH20_RS07280	COG0681	Belongs to the peptidase S26 family
LXH20_RS07290	COG0488	(ABC) transporter
LXH20_RS07295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LXH20_RS07300	COG2309	aminopeptidase activity
LXH20_RS07310	COG1077	Cell shape determining protein MreB Mrl
LXH20_RS07315	COG2002	toxin-antitoxin pair type II binding
LXH20_RS07320	COG3852	Histidine kinase
LXH20_RS07325	COG2105	PFAM AIG2 family protein
LXH20_RS07325	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LXH20_RS07330	COG0569	domain protein
LXH20_RS07340	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LXH20_RS07350	COG0561	phosphatase activity
LXH20_RS07355	COG0242	peptide deformylase activity
LXH20_RS07365	COG0497	DNA recombination
LXH20_RS07375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS07375	COG3321	synthase
LXH20_RS07375	COG4221	oxidoreductase activity
LXH20_RS07375	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS07380	COG0300	oxidoreductase activity
LXH20_RS07380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXH20_RS07380	COG4221	oxidoreductase activity
LXH20_RS07380	COG3321	synthase
LXH20_RS07385	COG4221	oxidoreductase activity
LXH20_RS07385	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS07385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS07385	COG3321	synthase
LXH20_RS07390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXH20_RS07390	COG0300	oxidoreductase activity
LXH20_RS07390	COG3321	synthase
LXH20_RS07390	COG4221	oxidoreductase activity
LXH20_RS07395	COG3321	synthase
LXH20_RS07395	COG4221	oxidoreductase activity
LXH20_RS07395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXH20_RS07395	COG0300	oxidoreductase activity
LXH20_RS07400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXH20_RS07400	COG0300	oxidoreductase activity
LXH20_RS07400	COG4221	oxidoreductase activity
LXH20_RS07400	COG3321	synthase
LXH20_RS07405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS07405	COG4221	oxidoreductase activity
LXH20_RS07405	COG3321	synthase
LXH20_RS07405	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS07410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LXH20_RS07415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LXH20_RS07420	COG0022	dehydrogenase e1 component
LXH20_RS07425	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXH20_RS07430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXH20_RS07435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXH20_RS07450	COG1982	Orn Lys Arg decarboxylase major
LXH20_RS07470	COG0483	inositol monophosphate 1-phosphatase activity
LXH20_RS07480	COG3227	Zinc metalloprotease (Elastase)
LXH20_RS07495	COG1595	DNA-templated transcription, initiation
LXH20_RS07515	COG1217	gtp-binding protein TYPA
LXH20_RS07525	COG4896	Protein conserved in bacteria
LXH20_RS07535	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LXH20_RS07540	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LXH20_RS07545	COG2066	Belongs to the glutaminase family
LXH20_RS07555	COG0772	Belongs to the SEDS family
LXH20_RS07560	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LXH20_RS07575	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LXH20_RS07575	COG2010	Cytochrome c
LXH20_RS07580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LXH20_RS07585	COG1845	cytochrome c oxidase, subunit III
LXH20_RS07590	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LXH20_RS07595	COG3336	cytochrome c oxidase
LXH20_RS07605	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LXH20_RS07610	COG2340	Cysteine-rich secretory protein family
LXH20_RS07625	COG3679	Belongs to the UPF0342 family
LXH20_RS07635	COG0742	ribosomal rna small subunit methyltransferase
LXH20_RS07645	COG3314	Sporulation integral membrane protein YlbJ
LXH20_RS07650	COG1752	Esterase of the alpha-beta hydrolase superfamily
LXH20_RS07655	COG3480	Lon protease (S16) C-terminal proteolytic domain
LXH20_RS07665	COG1399	metal-binding, possibly nucleic acid-binding protein
LXH20_RS07685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LXH20_RS07705	COG4839	cell division protein FtsL
LXH20_RS07710	COG0768	penicillin binding
LXH20_RS07715	COG0768	penicillin binding
LXH20_RS07735	COG0772	Belongs to the SEDS family
LXH20_RS07750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LXH20_RS07755	COG0849	cell division
LXH20_RS07760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LXH20_RS07765	COG1404	Belongs to the peptidase S8 family
LXH20_RS07765	COG4412	M6 family metalloprotease domain protein
LXH20_RS07775	COG1191	sigma factor activity
LXH20_RS07780	COG1191	sigma factor activity
LXH20_RS07785	COG1119	ATPase activity
LXH20_RS07790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LXH20_RS07795	COG1873	PFAM PRC-barrel domain
LXH20_RS07800	COG1496	oxidoreductase activity
LXH20_RS07805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LXH20_RS07815	COG0762	integral membrane protein
LXH20_RS07820	COG2302	S4 RNA-binding domain
LXH20_RS07825	COG3599	regulation of cell shape
LXH20_RS07830	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LXH20_RS07835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LXH20_RS07845	COG0564	pseudouridine synthase activity
LXH20_RS07855	COG2233	PERMEase
LXH20_RS07865	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LXH20_RS07870	COG0505	Belongs to the CarA family
LXH20_RS07875	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LXH20_RS07890	COG0284	orotidine-5'-phosphate decarboxylase activity
LXH20_RS07895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LXH20_RS07905	COG0306	phosphate transporter
LXH20_RS07920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LXH20_RS07925	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
LXH20_RS07930	COG1648	precorrin-2 dehydrogenase activity
LXH20_RS07945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LXH20_RS07950	COG1561	YicC-like family, N-terminal region
LXH20_RS07960	COG0194	GDP metabolic process
LXH20_RS07970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LXH20_RS07975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LXH20_RS07980	COG0242	peptide deformylase activity
LXH20_RS07990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LXH20_RS07990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LXH20_RS08000	COG0631	protein serine/threonine phosphatase activity
LXH20_RS08005	COG0515	serine threonine protein kinase
LXH20_RS08005	COG2815	serine threonine protein kinase
LXH20_RS08015	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LXH20_RS08020	COG1564	THIamine pyrophosphokinase
LXH20_RS08035	COG1302	Protein conserved in bacteria
LXH20_RS08040	COG1461	Dihydroxyacetone kinase
LXH20_RS08045	COG1760	l-serine dehydratase
LXH20_RS08050	COG1760	l-serine dehydratase
LXH20_RS08055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LXH20_RS08070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LXH20_RS08075	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS08090	COG1196	nuclear chromosome segregation
LXH20_RS08095	COG0552	protein localization to endoplasmic reticulum
LXH20_RS08110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LXH20_RS08120	COG1837	Belongs to the UPF0109 family
LXH20_RS08145	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LXH20_RS08160	COG2257	FlhB HrpN YscU SpaS Family
LXH20_RS08170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LXH20_RS08175	COG0758	DNA mediated transformation
LXH20_RS08180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LXH20_RS08190	COG4974	Belongs to the 'phage' integrase family
LXH20_RS08210	COG1815	bacterial-type flagellum-dependent cell motility
LXH20_RS08215	COG1558	bacterial-type flagellum-dependent cell motility
LXH20_RS08220	COG1677	Flagellar hook-basal body complex protein FliE
LXH20_RS08225	COG1766	The M ring may be actively involved in energy transduction
LXH20_RS08230	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LXH20_RS08235	COG1317	bacterial-type flagellum organization
LXH20_RS08240	COG1157	protein secretion by the type III secretion system
LXH20_RS08245	COG2882	bacterial-type flagellum organization
LXH20_RS08250	COG3334	PFAM MgtE intracellular
LXH20_RS08255	COG3144	bacterial-type flagellum assembly
LXH20_RS08260	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LXH20_RS08265	COG4786	Flagellar basal body rod
LXH20_RS08270	COG1582	Flagellar protein (FlbD)
LXH20_RS08275	COG1580	Controls the rotational direction of flagella during chemotaxis
LXH20_RS08280	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LXH20_RS08285	COG1776	CheC inhibitor of MCP methylation
LXH20_RS08285	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LXH20_RS08290	COG2201	protein-glutamate methylesterase activity
LXH20_RS08295	COG3190	flagellar
LXH20_RS08300	COG1338	Plays a role in the flagellum-specific transport system
LXH20_RS08305	COG1987	bacterial-type flagellum assembly
LXH20_RS08310	COG1684	flagellar biosynthetic protein fliR
LXH20_RS08315	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LXH20_RS08320	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LXH20_RS08325	COG1419	protein localization to endoplasmic reticulum
LXH20_RS08330	COG0455	bacterial-type flagellum organization
LXH20_RS08335	COG2201	protein-glutamate methylesterase activity
LXH20_RS08340	COG2198	Histidine kinase
LXH20_RS08340	COG0643	Histidine kinase
LXH20_RS08345	COG0835	chemotaxis
LXH20_RS08350	COG1776	CheC inhibitor of MCP methylation
LXH20_RS08360	COG1191	sigma factor activity
LXH20_RS08390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LXH20_RS08395	COG4589	Belongs to the CDS family
LXH20_RS08405	COG0750	zinc metalloprotease
LXH20_RS08415	COG2176	DNA-directed DNA polymerase activity
LXH20_RS08425	COG0195	Participates in both transcription termination and antitermination
LXH20_RS08430	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LXH20_RS08435	COG1358	cellular component organization or biogenesis
LXH20_RS08445	COG1550	Protein conserved in bacteria
LXH20_RS08460	COG0196	riboflavin kinase activity
LXH20_RS08475	COG0726	polysaccharide deacetylase
LXH20_RS08480	COG0612	Peptidase, M16
LXH20_RS08485	COG1873	PFAM PRC-barrel domain
LXH20_RS08490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LXH20_RS08495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LXH20_RS08500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LXH20_RS08505	COG0527	aspartate kinase activity
LXH20_RS08515	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LXH20_RS08520	COG0740	serine-type endopeptidase activity
LXH20_RS08530	COG1674	ftsk spoiiie
LXH20_RS08530	COG4980	gas vesicle protein
LXH20_RS08535	COG2188	Transcriptional regulator
LXH20_RS08540	COG2814	Major facilitator Superfamily
LXH20_RS08545	COG1846	Transcriptional regulator
LXH20_RS08550	COG1033	growth of symbiont in host cell
LXH20_RS08550	COG2409	Drug exporters of the RND superfamily
LXH20_RS08555	COG0612	Peptidase, M16
LXH20_RS08560	COG0612	Peptidase, M16
LXH20_RS08565	COG0300	oxidoreductase activity
LXH20_RS08580	COG1426	Protein conserved in bacteria
LXH20_RS08585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LXH20_RS08600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LXH20_RS08610	COG1692	metallophosphoesterase
LXH20_RS08615	COG2359	stage V sporulation protein S
LXH20_RS08635	COG4550	Control of competence regulator ComK, YlbF/YmcA
LXH20_RS08710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXH20_RS08715	COG3425	synthase
LXH20_RS08720	COG1024	Enoyl-CoA hydratase
LXH20_RS08725	COG1024	Enoyl-CoA hydratase
LXH20_RS08730	COG0300	oxidoreductase activity
LXH20_RS08730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS08730	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS08730	COG3321	synthase
LXH20_RS08730	COG0318	PFAM AMP-dependent synthetase and ligase
LXH20_RS08735	COG4221	oxidoreductase activity
LXH20_RS08735	COG3321	synthase
LXH20_RS08735	COG0300	oxidoreductase activity
LXH20_RS08735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXH20_RS08740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXH20_RS08740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXH20_RS08740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXH20_RS08740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS08740	COG3321	synthase
LXH20_RS08740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXH20_RS08740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS08740	COG3321	synthase
LXH20_RS08745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS08745	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS08745	COG3321	synthase
LXH20_RS08745	COG4221	oxidoreductase activity
LXH20_RS08750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXH20_RS08750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LXH20_RS08750	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LXH20_RS08750	COG3321	synthase
LXH20_RS08755	COG2124	cytochrome p450
LXH20_RS08760	COG3209	COG3209 Rhs family protein
LXH20_RS08765	COG3619	membrane
LXH20_RS08775	COG1404	Belongs to the peptidase S8 family
LXH20_RS08785	COG4195	phage-related replication protein
LXH20_RS08790	COG1764	response to oxidative stress
LXH20_RS08800	COG2076	Multidrug Resistance protein
LXH20_RS08840	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LXH20_RS08845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LXH20_RS08850	COG4112	unkown
LXH20_RS08855	COG0860	N-Acetylmuramoyl-L-alanine amidase
LXH20_RS08860	COG0464	growth
LXH20_RS08865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LXH20_RS08870	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LXH20_RS08875	COG0789	Transcriptional regulator
LXH20_RS08880	COG0174	glutamine synthetase
LXH20_RS08905	COG2211	Major facilitator Superfamily
LXH20_RS08910	COG3507	Belongs to the glycosyl hydrolase 43 family
LXH20_RS08925	COG1070	Carbohydrate kinase
LXH20_RS08930	COG3848	Pyruvate phosphate dikinase
LXH20_RS08930	COG0574	Belongs to the PEP-utilizing enzyme family
LXH20_RS08945	COG2378	regulation of single-species biofilm formation
LXH20_RS08950	COG2318	DinB family
LXH20_RS08955	COG1064	alcohol dehydrogenase
LXH20_RS08960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LXH20_RS08960	COG4451	ribulose bisphosphate carboxylase, small
LXH20_RS08980	COG0456	acetyltransferase
LXH20_RS08985	COG5444	nuclease activity
LXH20_RS09040	COG3397	chitin binding
LXH20_RS09050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXH20_RS09065	COG5434	Belongs to the glycosyl hydrolase 28 family
LXH20_RS09070	COG0756	dUTP diphosphatase activity
LXH20_RS09075	COG4195	phage-related replication protein
LXH20_RS09110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LXH20_RS09120	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LXH20_RS09140	COG0785	Cytochrome C biogenesis protein
LXH20_RS09145	COG2201	protein-glutamate methylesterase activity
LXH20_RS09150	COG4846	Membrane protein involved in cytochrome C biogenesis
LXH20_RS09160	COG0071	Belongs to the small heat shock protein (HSP20) family
LXH20_RS09175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LXH20_RS09180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXH20_RS09200	COG0824	Thioesterase
LXH20_RS09210	COG4841	protein insertion into membrane
LXH20_RS09220	COG1832	CoA-binding protein
LXH20_RS09225	COG0187	DNA topoisomerase II activity
LXH20_RS09230	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LXH20_RS09240	COG1115	amino acid carrier protein
LXH20_RS09250	COG1063	alcohol dehydrogenase
LXH20_RS09255	COG0800	Aldolase
LXH20_RS09260	COG1312	Catalyzes the dehydration of D-mannonate
LXH20_RS09265	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS09270	COG1609	Transcriptional regulator
LXH20_RS09275	COG2271	Major facilitator Superfamily
LXH20_RS09320	COG2205	protein histidine kinase activity
LXH20_RS09325	COG0745	RESPONSE REGULATOR receiver
LXH20_RS09335	COG3507	Belongs to the glycosyl hydrolase 43 family
LXH20_RS09360	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS09365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LXH20_RS09370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LXH20_RS09375	COG2610	gluconate transmembrane transporter activity
LXH20_RS09380	COG2124	cytochrome p450
LXH20_RS09400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LXH20_RS09410	COG2246	polysaccharide biosynthetic process
LXH20_RS09415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LXH20_RS09420	COG0586	Pfam SNARE associated Golgi protein
LXH20_RS09425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LXH20_RS09430	COG1024	Enoyl-CoA hydratase
LXH20_RS09435	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LXH20_RS09440	COG0511	ligase activity, forming carbon-carbon bonds
LXH20_RS09445	COG0439	Biotin carboxylase
LXH20_RS09450	COG0318	PFAM AMP-dependent synthetase and ligase
LXH20_RS09455	COG1960	acyl-CoA dehydrogenase activity
LXH20_RS09460	COG1649	PFAM Uncharacterised BCR, COG1649
LXH20_RS09470	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LXH20_RS09470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS09475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS09480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS09485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS09490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS09495	COG2027	D-alanyl-D-alanine carboxypeptidase
LXH20_RS09500	COG2017	converts alpha-aldose to the beta-anomer
LXH20_RS09505	COG0534	Mate efflux family protein
LXH20_RS09520	COG0582	viral genome integration into host DNA
LXH20_RS09525	COG0166	Belongs to the GPI family
LXH20_RS09530	COG0405	Gamma-glutamyltransferase
LXH20_RS09535	COG2814	Major facilitator Superfamily
LXH20_RS09540	COG0640	Transcriptional regulator
LXH20_RS09545	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LXH20_RS09555	COG0604	alcohol dehydrogenase
LXH20_RS09565	COG0493	'glutamate synthase
LXH20_RS09570	COG0067	glutamate synthase
LXH20_RS09570	COG0070	glutamate synthase
LXH20_RS09570	COG0069	glutamate synthase activity
LXH20_RS09575	COG0583	DNA-binding transcription factor activity
LXH20_RS09580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LXH20_RS09595	COG0300	oxidoreductase activity
LXH20_RS09600	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LXH20_RS09610	COG2814	Major facilitator Superfamily
LXH20_RS09615	COG1070	Carbohydrate kinase
LXH20_RS09620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LXH20_RS09625	COG0243	molybdopterin cofactor binding
LXH20_RS09655	COG5444	nuclease activity
LXH20_RS09660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXH20_RS09665	COG0662	Cupin 2, conserved barrel domain protein
LXH20_RS09665	COG2207	Transcriptional regulator
LXH20_RS09670	COG1309	transcriptional regulator
LXH20_RS09675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXH20_RS09685	COG0640	Transcriptional regulator
LXH20_RS09690	COG0741	lytic transglycosylase activity
LXH20_RS09695	COG2322	membrane
LXH20_RS09710	COG1619	proteins homologs of microcin C7 resistance protein MccF
LXH20_RS09720	COG1388	LysM domain
LXH20_RS09720	COG3584	3D domain protein
LXH20_RS09725	COG0514	ATP-dependent DNA helicase (RecQ)
LXH20_RS09735	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LXH20_RS09740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LXH20_RS09755	COG0071	Belongs to the small heat shock protein (HSP20) family
LXH20_RS09785	COG1012	belongs to the aldehyde dehydrogenase family
LXH20_RS09790	COG1657	PFAM Prenyltransferase squalene oxidase
LXH20_RS09795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LXH20_RS09800	COG0733	neurotransmitter:sodium symporter activity
LXH20_RS09805	COG0385	Bile acid
LXH20_RS09810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXH20_RS09815	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXH20_RS09825	COG4548	von Willebrand factor, type A
LXH20_RS09830	COG0714	Associated with various cellular activities
LXH20_RS09835	COG2032	superoxide dismutase activity
LXH20_RS09840	COG0791	NLP P60 protein
LXH20_RS09840	COG1388	LysM domain
LXH20_RS09845	COG1819	glycosyl
LXH20_RS09850	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LXH20_RS09855	COG0534	Mate efflux family protein
LXH20_RS09860	COG1366	Belongs to the anti-sigma-factor antagonist family
LXH20_RS09865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LXH20_RS09870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LXH20_RS09880	COG2962	Rard protein
LXH20_RS09895	COG1942	4-Oxalocrotonate Tautomerase
LXH20_RS09905	COG1733	regulation of RNA biosynthetic process
LXH20_RS09910	COG0778	Nitroreductase
LXH20_RS09915	COG0400	carboxylic ester hydrolase activity
LXH20_RS09920	COG0346	lactoylglutathione lyase activity
LXH20_RS09930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXH20_RS09940	COG2723	6-phospho-beta-galactosidase activity
LXH20_RS09945	COG2188	Transcriptional regulator
LXH20_RS09950	COG3409	Peptidoglycan-binding domain 1 protein
LXH20_RS09950	COG0793	Belongs to the peptidase S41A family
LXH20_RS09955	COG2226	methyltransferase
LXH20_RS09965	COG1876	peptidase activity
LXH20_RS09985	COG0671	phosphoesterase, PA-phosphatase related
LXH20_RS10015	COG1509	lysine 2,3-aminomutase activity
LXH20_RS10020	COG0456	acetyltransferase
LXH20_RS10025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LXH20_RS10030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LXH20_RS10035	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LXH20_RS10040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LXH20_RS10045	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LXH20_RS10055	COG0456	acetyltransferase
LXH20_RS10060	COG0463	Glycosyl transferase, family 2
LXH20_RS10075	COG4641	Protein conserved in bacteria
LXH20_RS10085	COG1086	Polysaccharide biosynthesis protein
LXH20_RS10110	COG1388	LysM domain
LXH20_RS10115	COG0457	Tetratricopeptide repeat
LXH20_RS10130	COG3391	amine dehydrogenase activity
LXH20_RS10150	COG3655	Transcriptional regulator
LXH20_RS10180	COG0457	Tetratricopeptide repeat
LXH20_RS10205	COG2197	response regulator
LXH20_RS10210	COG4585	Histidine kinase
LXH20_RS10215	COG0730	response to heat
LXH20_RS10240	COG5444	nuclease activity
LXH20_RS10245	COG4282	regulation of fungal-type cell wall biogenesis
LXH20_RS10250	COG1525	nuclease
LXH20_RS10285	COG1846	Transcriptional regulator
LXH20_RS10290	COG4698	Protein conserved in bacteria
LXH20_RS10295	COG2755	lipolytic protein G-D-S-L family
LXH20_RS10300	COG1999	signal sequence binding
LXH20_RS10310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LXH20_RS10315	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LXH20_RS10320	COG1272	protein, Hemolysin III
LXH20_RS10325	COG0204	Acyl-transferase
LXH20_RS10330	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LXH20_RS10345	COG2136	Putative SAM-dependent methyltransferase
LXH20_RS10345	COG2521	methyltransferase
LXH20_RS10360	COG1413	lyase activity
LXH20_RS10365	COG1418	mRNA catabolic process
LXH20_RS10370	COG0386	Belongs to the glutathione peroxidase family
LXH20_RS10380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LXH20_RS10390	COG1278	Cold shock
LXH20_RS10410	COG0328	RNA-DNA hybrid ribonuclease activity
LXH20_RS10415	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LXH20_RS10420	COG0328	RNA-DNA hybrid ribonuclease activity
LXH20_RS10430	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LXH20_RS10445	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LXH20_RS10455	COG1755	Isoprenylcysteine carboxyl methyltransferase
LXH20_RS10460	COG3424	synthase
LXH20_RS10480	COG1335	isochorismatase
LXH20_RS10490	COG2233	PERMEase
LXH20_RS10500	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LXH20_RS10505	COG1199	ATP-dependent helicase activity
LXH20_RS10520	COG0116	Belongs to the methyltransferase superfamily
LXH20_RS10550	COG3359	exonuclease
LXH20_RS10555	COG1111	helicase
LXH20_RS10555	COG1205	dead DEAH box helicase
LXH20_RS10560	COG2190	(PTS) system
LXH20_RS10565	COG0071	Belongs to the small heat shock protein (HSP20) family
LXH20_RS10605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXH20_RS10605	COG4499	WXG100 protein secretion system (Wss), protein YukC
LXH20_RS10615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LXH20_RS10620	COG3935	DnaD domain protein
LXH20_RS10630	COG0436	Aminotransferase
LXH20_RS10635	COG5353	protein conserved in bacteria
LXH20_RS10645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LXH20_RS10645	COG1199	ATP-dependent helicase activity
LXH20_RS10675	COG0438	transferase activity, transferring glycosyl groups
LXH20_RS10680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LXH20_RS10695	COG1694	Mazg nucleotide pyrophosphohydrolase
LXH20_RS10700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXH20_RS10705	COG2140	Oxalate decarboxylase
LXH20_RS10715	COG4347	Protein of unknown function (DUF1405)
LXH20_RS10720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LXH20_RS10720	COG2010	Cytochrome c
LXH20_RS10725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LXH20_RS10730	COG0723	plastoquinol--plastocyanin reductase activity
LXH20_RS10745	COG0457	Tetratricopeptide repeat
LXH20_RS10755	COG0287	Prephenate dehydrogenase
LXH20_RS10790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LXH20_RS10795	COG4401	Chorismate mutase type I
LXH20_RS10810	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LXH20_RS10815	COG0105	UTP biosynthetic process
LXH20_RS10820	COG0142	geranyltranstransferase activity
LXH20_RS10830	COG0142	geranyltranstransferase activity
LXH20_RS10845	COG0776	regulation of translation
LXH20_RS10850	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LXH20_RS10890	COG0539	negative regulation of cytoplasmic translation
LXH20_RS10905	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LXH20_RS10910	COG2959	enzyme of heme biosynthesis
LXH20_RS10915	COG3773	Cell wall hydrolase
LXH20_RS10915	COG3409	Peptidoglycan-binding domain 1 protein
LXH20_RS10920	COG2339	peptidase activity
LXH20_RS10925	COG0492	ferredoxin-NADP+ reductase activity
LXH20_RS10930	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LXH20_RS10935	COG4862	establishment of competence for transformation
LXH20_RS10940	COG1408	metallophosphoesterase
LXH20_RS10950	COG1388	LysM domain
LXH20_RS10955	COG1266	CAAX protease self-immunity
LXH20_RS10960	COG0514	ATP-dependent DNA helicase (RecQ)
LXH20_RS10965	COG4955	Helix-turn-helix domain
LXH20_RS10970	COG1141	Ferredoxin
LXH20_RS10975	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LXH20_RS10980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LXH20_RS10990	COG1595	DNA-templated transcription, initiation
LXH20_RS10995	COG5002	protein histidine kinase activity
LXH20_RS11000	COG0745	RESPONSE REGULATOR receiver
LXH20_RS11005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LXH20_RS11010	COG1333	cytochrome c biogenesis protein
LXH20_RS11015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXH20_RS11020	COG1187	pseudouridine synthase activity
LXH20_RS11025	COG0700	Nucleoside recognition
LXH20_RS11030	COG2715	membrane protein required for spore maturation
LXH20_RS11035	COG1686	Belongs to the peptidase S11 family
LXH20_RS11060	COG1547	Domain of unknown function (DUF309)
LXH20_RS11065	COG0456	acetyltransferase
LXH20_RS11080	COG0307	riboflavin synthase, alpha
LXH20_RS11085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LXH20_RS11085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LXH20_RS11095	COG0681	Belongs to the peptidase S26 family
LXH20_RS11105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LXH20_RS11110	COG4086	secreted protein
LXH20_RS11115	COG0019	diaminopimelate decarboxylase activity
LXH20_RS11120	COG0697	spore germination
LXH20_RS11135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LXH20_RS11155	COG1191	sigma factor activity
LXH20_RS11165	COG1366	Belongs to the anti-sigma-factor antagonist family
LXH20_RS11170	COG1686	Belongs to the peptidase S11 family
LXH20_RS11175	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LXH20_RS11180	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LXH20_RS11185	COG4974	Belongs to the 'phage' integrase family
LXH20_RS11195	COG0735	belongs to the Fur family
LXH20_RS11200	COG1300	Membrane
LXH20_RS11215	COG0281	malic enzyme
LXH20_RS11220	COG1757	Na H antiporter
LXH20_RS11225	COG1027	Aspartate ammonia-lyase
LXH20_RS11230	COG0252	asparaginase activity
LXH20_RS11235	COG1396	sequence-specific DNA binding
LXH20_RS11240	COG1379	DNA repair
LXH20_RS11245	COG0494	nUDIX hydrolase
LXH20_RS11255	COG0667	Aldo Keto reductase
LXH20_RS11265	COG1073	alpha beta
LXH20_RS11275	COG4918	Iron-sulphur cluster biosynthesis
LXH20_RS11280	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LXH20_RS11280	COG0456	acetyltransferase
LXH20_RS11285	COG2329	Antibiotic biosynthesis monooxygenase
LXH20_RS11290	COG0456	acetyltransferase
LXH20_RS11295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LXH20_RS11310	COG0628	permease
LXH20_RS11320	COG0346	lactoylglutathione lyase activity
LXH20_RS11330	COG3048	D-serine ammonia-lyase activity
LXH20_RS11335	COG0300	oxidoreductase activity
LXH20_RS11340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXH20_RS11345	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LXH20_RS11350	COG1024	Enoyl-CoA hydratase
LXH20_RS11355	COG3425	synthase
LXH20_RS11360	COG2124	cytochrome p450
LXH20_RS11365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXH20_RS11365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS11365	COG3321	synthase
LXH20_RS11365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXH20_RS11365	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS11370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXH20_RS11370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXH20_RS11370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS11370	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS11370	COG3321	synthase
LXH20_RS11375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS11375	COG0300	oxidoreductase activity
LXH20_RS11375	COG0318	PFAM AMP-dependent synthetase and ligase
LXH20_RS11375	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS11375	COG3321	synthase
LXH20_RS11380	COG0300	oxidoreductase activity
LXH20_RS11380	COG0318	PFAM AMP-dependent synthetase and ligase
LXH20_RS11380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS11380	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS11380	COG3321	synthase
LXH20_RS11385	COG3321	synthase
LXH20_RS11385	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS11385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS11385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXH20_RS11385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXH20_RS11390	COG3321	synthase
LXH20_RS11390	COG0300	oxidoreductase activity
LXH20_RS11390	COG0318	PFAM AMP-dependent synthetase and ligase
LXH20_RS11390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS11390	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS11395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS11395	COG3321	synthase
LXH20_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS11395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXH20_RS11395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXH20_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS11405	COG0318	PFAM AMP-dependent synthetase and ligase
LXH20_RS11420	COG2070	2-Nitropropane dioxygenase
LXH20_RS11420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LXH20_RS11425	COG0250	Participates in transcription elongation, termination and antitermination
LXH20_RS11450	COG0596	Alpha beta hydrolase
LXH20_RS11465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LXH20_RS11470	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LXH20_RS11485	COG0706	membrane insertase activity
LXH20_RS11490	COG2195	Cleaves the N-terminal amino acid of tripeptides
LXH20_RS11495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LXH20_RS11500	COG0346	lactoylglutathione lyase activity
LXH20_RS11510	COG1376	ErfK ybiS ycfS ynhG family protein
LXH20_RS11515	COG4129	membrane
LXH20_RS11520	COG1126	abc transporter atp-binding protein
LXH20_RS11525	COG0765	amino acid transport
LXH20_RS11530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXH20_RS11540	COG1597	lipid kinase activity
LXH20_RS11545	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXH20_RS11550	COG0022	dehydrogenase e1 component
LXH20_RS11555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LXH20_RS11560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXH20_RS11565	COG3426	butyrate kinase activity
LXH20_RS11570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LXH20_RS11575	COG0280	phosphate acetyltransferase
LXH20_RS11580	COG3829	transcription factor binding
LXH20_RS11580	COG3290	protein histidine kinase activity
LXH20_RS11590	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LXH20_RS11595	COG2079	MmgE PrpD family protein
LXH20_RS11600	COG0372	Belongs to the citrate synthase family
LXH20_RS11605	COG1960	acyl-CoA dehydrogenase activity
LXH20_RS11610	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXH20_RS11615	COG0183	Belongs to the thiolase family
LXH20_RS11620	COG0584	glycerophosphoryl diester phosphodiesterase
LXH20_RS11625	COG0860	N-Acetylmuramoyl-L-alanine amidase
LXH20_RS11650	COG1902	pentaerythritol trinitrate reductase activity
LXH20_RS11665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LXH20_RS11670	COG0745	RESPONSE REGULATOR receiver
LXH20_RS11675	COG0750	zinc metalloprotease
LXH20_RS11680	COG0497	DNA recombination
LXH20_RS11690	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LXH20_RS11700	COG0142	geranyltranstransferase activity
LXH20_RS11710	COG1570	exodeoxyribonuclease VII activity
LXH20_RS11725	COG1302	Protein conserved in bacteria
LXH20_RS11730	COG0439	Biotin carboxylase
LXH20_RS11735	COG0511	ligase activity, forming carbon-carbon bonds
LXH20_RS11775	COG3854	ATPases associated with a variety of cellular activities
LXH20_RS11790	COG0006	proline dipeptidase activity
LXH20_RS11800	COG3872	metal-dependent enzyme
LXH20_RS11810	COG1752	Esterase of the alpha-beta hydrolase superfamily
LXH20_RS11825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LXH20_RS11845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LXH20_RS11860	COG1396	sequence-specific DNA binding
LXH20_RS11870	COG0681	Belongs to the peptidase S26 family
LXH20_RS11895	COG4940	Competence protein ComGF
LXH20_RS11905	COG4970	Tfp pilus assembly protein FimT
LXH20_RS11910	COG4537	Required for transformation and DNA binding
LXH20_RS11915	COG1459	type II secretion system
LXH20_RS11920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LXH20_RS11925	COG0598	Magnesium transport protein CorA
LXH20_RS11930	COG1253	flavin adenine dinucleotide binding
LXH20_RS11935	COG1366	Belongs to the anti-sigma-factor antagonist family
LXH20_RS11945	COG1393	Belongs to the ArsC family
LXH20_RS11955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXH20_RS11965	COG0011	TIGRFAM Protein of
LXH20_RS11975	COG2866	Carboxypeptidase
LXH20_RS11980	COG1940	carbohydrate kinase activity
LXH20_RS11985	COG4483	Protein conserved in bacteria
LXH20_RS11990	COG1757	Na H antiporter
LXH20_RS12000	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LXH20_RS12015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LXH20_RS12020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LXH20_RS12025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LXH20_RS12030	COG0581	inorganic phosphate transmembrane transporter activity
LXH20_RS12035	COG0573	inorganic phosphate transmembrane transporter activity
LXH20_RS12040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LXH20_RS12045	COG0768	penicillin binding
LXH20_RS12050	COG0477	Major facilitator Superfamily
LXH20_RS12055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LXH20_RS12060	COG2839	Protein conserved in bacteria
LXH20_RS12065	COG5521	maltodextrose utilization protein MalA
LXH20_RS12070	COG1388	LysM domain
LXH20_RS12080	COG4709	membrane
LXH20_RS12085	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
LXH20_RS12090	COG0735	belongs to the Fur family
LXH20_RS12095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXH20_RS12110	COG0513	Belongs to the DEAD box helicase family
LXH20_RS12125	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LXH20_RS12130	COG2384	SAM-dependent methyltransferase
LXH20_RS12135	COG2010	Cytochrome c
LXH20_RS12140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LXH20_RS12145	COG0358	DNA primase activity
LXH20_RS12160	COG0517	IMP dehydrogenase activity
LXH20_RS12165	COG0751	glycine-tRNA ligase activity
LXH20_RS12185	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LXH20_RS12190	COG0295	cytidine deaminase activity
LXH20_RS12195	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LXH20_RS12205	COG1480	7TM receptor with intracellular HD hydrolase
LXH20_RS12210	COG1702	phosphate starvation-inducible protein PhoH
LXH20_RS12215	COG0561	phosphatase activity
LXH20_RS12230	COG4864	UPF0365 protein
LXH20_RS12235	COG1030	water channel activity
LXH20_RS12240	COG1610	YqeY-like protein
LXH20_RS12250	COG1283	sodium-dependent phosphate transmembrane transporter activity
LXH20_RS12255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LXH20_RS12260	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LXH20_RS12290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LXH20_RS12305	COG0860	N-Acetylmuramoyl-L-alanine amidase
LXH20_RS12335	COG2333	competence protein COMEC
LXH20_RS12335	COG0658	competence protein
LXH20_RS12340	COG2131	deaminase
LXH20_RS12345	COG1555	photosystem II stabilization
LXH20_RS12345	COG1596	polysaccharide export
LXH20_RS12350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LXH20_RS12355	COG2226	methyltransferase
LXH20_RS12360	COG0799	negative regulation of ribosome biogenesis
LXH20_RS12365	COG1713	HD superfamily hydrolase involved in NAD metabolism
LXH20_RS12375	COG1534	Rna-binding protein
LXH20_RS12380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LXH20_RS12385	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LXH20_RS12390	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LXH20_RS12400	COG2755	lipolytic protein G-D-S-L family
LXH20_RS12410	COG0398	Pfam SNARE associated Golgi protein
LXH20_RS12435	COG2207	Transcriptional regulator
LXH20_RS12435	COG3708	Transcriptional regulator
LXH20_RS12440	COG0583	DNA-binding transcription factor activity
LXH20_RS12455	COG0642	Histidine kinase
LXH20_RS12455	COG5002	protein histidine kinase activity
LXH20_RS12460	COG0745	RESPONSE REGULATOR receiver
LXH20_RS12465	COG2311	Membrane
LXH20_RS12475	COG0454	-acetyltransferase
LXH20_RS12490	COG2814	Major facilitator Superfamily
LXH20_RS12505	COG5444	nuclease activity
LXH20_RS12540	COG0456	acetyltransferase
LXH20_RS12545	COG2318	DinB family
LXH20_RS12555	COG0561	phosphatase activity
LXH20_RS12560	COG0561	phosphatase activity
LXH20_RS12570	COG1482	cell wall glycoprotein biosynthetic process
LXH20_RS12575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXH20_RS12575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXH20_RS12575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXH20_RS12580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXH20_RS12580	COG3711	transcriptional antiterminator
LXH20_RS12590	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LXH20_RS12595	COG0583	DNA-binding transcription factor activity
LXH20_RS12600	COG2814	Major facilitator Superfamily
LXH20_RS12605	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LXH20_RS12605	COG2124	cytochrome p450
LXH20_RS12610	COG1309	transcriptional regulator
LXH20_RS12615	COG2226	methyltransferase
LXH20_RS12630	COG2116	formate transmembrane transporter activity
LXH20_RS12635	COG5609	conserved protein (DUF2294)
LXH20_RS12640	COG3383	formate dehydrogenase (NAD+) activity
LXH20_RS12645	COG2427	Protein of unknown function (DUF1641)
LXH20_RS12655	COG0626	cystathionine gamma-synthase activity
LXH20_RS12660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LXH20_RS12685	COG0768	penicillin binding
LXH20_RS12700	COG0826	peptidase U32
LXH20_RS12705	COG0826	peptidase U32
LXH20_RS12710	COG4122	O-methyltransferase activity
LXH20_RS12715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LXH20_RS12730	COG4472	Bacterial protein of unknown function (DUF965)
LXH20_RS12740	COG0628	permease
LXH20_RS12745	COG1126	abc transporter atp-binding protein
LXH20_RS12750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXH20_RS12755	COG0765	amino acid transport
LXH20_RS12760	COG0765	amino acid transport
LXH20_RS12775	COG3881	PFAM PRC-barrel domain
LXH20_RS12780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LXH20_RS12785	COG0457	Tetratricopeptide repeat
LXH20_RS12795	COG1104	cysteine desulfurase activity
LXH20_RS12800	COG1959	2 iron, 2 sulfur cluster binding
LXH20_RS12805	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LXH20_RS12810	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LXH20_RS12835	COG3103	Sh3 type 3 domain protein
LXH20_RS12835	COG4991	sh3 domain protein
LXH20_RS12835	COG0860	N-Acetylmuramoyl-L-alanine amidase
LXH20_RS12845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LXH20_RS12855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LXH20_RS12855	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LXH20_RS12860	COG5416	Lipopolysaccharide assembly protein A domain
LXH20_RS12865	COG0490	domain, Protein
LXH20_RS12870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LXH20_RS12870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LXH20_RS12880	COG2244	polysaccharide biosynthetic process
LXH20_RS12885	COG2323	membrane
LXH20_RS12895	COG1862	Preprotein translocase
LXH20_RS12935	COG1388	LysM domain
LXH20_RS12945	COG0157	Belongs to the NadC ModD family
LXH20_RS12950	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LXH20_RS12955	COG1104	cysteine desulfurase activity
LXH20_RS12960	COG1827	regulation of RNA biosynthetic process
LXH20_RS12965	COG0077	Prephenate dehydratase
LXH20_RS12980	COG3290	protein histidine kinase activity
LXH20_RS12985	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LXH20_RS12990	COG2868	ribosomal protein
LXH20_RS13000	COG1994	Peptidase M50
LXH20_RS13005	COG0739	heme binding
LXH20_RS13010	COG2894	cell division
LXH20_RS13020	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LXH20_RS13030	COG1077	Cell shape determining protein MreB Mrl
LXH20_RS13050	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LXH20_RS13055	COG0285	dihydrofolate synthase activity
LXH20_RS13060	COG0525	valine-tRNA ligase activity
LXH20_RS13070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LXH20_RS13075	COG1388	LysM domain
LXH20_RS13085	COG0113	porphobilinogen synthase activity
LXH20_RS13090	COG1587	Uroporphyrinogen-III synthase
LXH20_RS13100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LXH20_RS13120	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LXH20_RS13125	COG0470	DNA polymerase III
LXH20_RS13125	COG1067	ATP-dependent peptidase activity
LXH20_RS13140	COG0457	Tetratricopeptide repeat
LXH20_RS13140	COG1477	protein flavinylation
LXH20_RS13155	COG0473	3-isopropylmalate dehydrogenase activity
LXH20_RS13170	COG0440	acetolactate synthase activity
LXH20_RS13175	COG0028	Belongs to the TPP enzyme family
LXH20_RS13210	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LXH20_RS13235	COG0622	Phosphoesterase
LXH20_RS13240	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LXH20_RS13250	COG5401	PFAM Sporulation and spore germination
LXH20_RS13260	COG1846	Transcriptional regulator
LXH20_RS13265	COG2197	response regulator
LXH20_RS13270	COG0824	Thioesterase
LXH20_RS13275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LXH20_RS13280	COG1053	succinate dehydrogenase
LXH20_RS13285	COG2009	succinate dehydrogenase
LXH20_RS13290	COG1719	4-vinyl reductase, 4VR
LXH20_RS13295	COG0527	aspartate kinase activity
LXH20_RS13305	COG3118	belongs to the thioredoxin family
LXH20_RS13310	COG3534	alpha-L-arabinofuranosidase
LXH20_RS13315	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LXH20_RS13320	COG2086	electron transfer activity
LXH20_RS13325	COG1024	Enoyl-CoA hydratase
LXH20_RS13330	COG1309	transcriptional regulator
LXH20_RS13335	COG0318	PFAM AMP-dependent synthetase and ligase
LXH20_RS13345	COG3766	membrane
LXH20_RS13355	COG1796	DNA polymerase
LXH20_RS13355	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LXH20_RS13360	COG1286	toxin biosynthetic process
LXH20_RS13375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXH20_RS13375	COG0072	phenylalanine-tRNA ligase activity
LXH20_RS13380	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LXH20_RS13385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LXH20_RS13395	COG3835	regulator
LXH20_RS13400	COG0277	FAD linked oxidase domain protein
LXH20_RS13405	COG0247	lactate metabolic process
LXH20_RS13410	COG1966	Carbon starvation protein
LXH20_RS13415	COG3534	alpha-L-arabinofuranosidase
LXH20_RS13420	COG0395	ABC-type sugar transport system, permease component
LXH20_RS13425	COG1175	transmembrane transport
LXH20_RS13430	COG1653	transport
LXH20_RS13440	COG0647	UMP catabolic process
LXH20_RS13445	COG0235	Class ii aldolase
LXH20_RS13450	COG1069	ribulokinase activity
LXH20_RS13455	COG2160	L-arabinose isomerase activity
LXH20_RS13460	COG3507	Belongs to the glycosyl hydrolase 43 family
LXH20_RS13465	COG1363	Peptidase, m42
LXH20_RS13475	COG3326	Membrane
LXH20_RS13490	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LXH20_RS13495	COG1346	cytolysis
LXH20_RS13500	COG1380	Effector of murein hydrolase LrgA
LXH20_RS13505	COG3279	Response regulator of the LytR AlgR family
LXH20_RS13510	COG3275	phosphorelay sensor kinase activity
LXH20_RS13515	COG1011	Hydrolase
LXH20_RS13530	COG0398	Pfam SNARE associated Golgi protein
LXH20_RS13535	COG1484	DNA-dependent DNA replication
LXH20_RS13540	COG3611	Membrane attachment protein
LXH20_RS13555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LXH20_RS13560	COG1733	regulation of RNA biosynthetic process
LXH20_RS13565	COG2814	Major facilitator Superfamily
LXH20_RS13570	COG0656	L-ascorbic acid biosynthetic process
LXH20_RS13575	COG0237	dephospho-CoA kinase activity
LXH20_RS13580	COG1971	Probably functions as a manganese efflux pump
LXH20_RS13585	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LXH20_RS13590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LXH20_RS13590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LXH20_RS13595	COG5002	protein histidine kinase activity
LXH20_RS13600	COG0745	RESPONSE REGULATOR receiver
LXH20_RS13610	COG0538	isocitrate dehydrogenase activity
LXH20_RS13615	COG0372	Belongs to the citrate synthase family
LXH20_RS13625	COG0457	Tetratricopeptide repeat
LXH20_RS13650	COG0628	permease
LXH20_RS13655	COG3030	protein affecting phage T7 exclusion by the F plasmid
LXH20_RS13660	COG0469	pyruvate kinase activity
LXH20_RS13680	COG0281	malic enzyme
LXH20_RS13685	COG0587	DNA-directed DNA polymerase activity
LXH20_RS13705	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LXH20_RS13715	COG4109	DRTGG domain
LXH20_RS13725	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS13740	COG0521	Mo-molybdopterin cofactor biosynthetic process
LXH20_RS13750	COG0827	DNA restriction-modification system
LXH20_RS13755	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LXH20_RS13760	COG3874	Sporulation protein YtfJ
LXH20_RS13770	COG1714	RDD family
LXH20_RS13775	COG0616	signal peptide processing
LXH20_RS13780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LXH20_RS13785	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LXH20_RS13790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXH20_RS13805	COG1104	cysteine desulfurase activity
LXH20_RS13810	COG1114	Component of the transport system for branched-chain amino acids
LXH20_RS13820	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LXH20_RS13825	COG1309	transcriptional regulator
LXH20_RS13830	COG1956	GAF domain-containing protein
LXH20_RS13835	COG2199	diguanylate cyclase activity
LXH20_RS13835	COG2203	Gaf domain
LXH20_RS13845	COG1012	belongs to the aldehyde dehydrogenase family
LXH20_RS13870	COG1017	nitric oxide dioxygenase activity
LXH20_RS13870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LXH20_RS13880	COG0693	protein deglycase activity
LXH20_RS13895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LXH20_RS13900	COG1378	Sugar-specific transcriptional regulator TrmB
LXH20_RS13920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXH20_RS13925	COG0454	-acetyltransferase
LXH20_RS13930	COG0517	IMP dehydrogenase activity
LXH20_RS13935	COG0123	including yeast histone deacetylase and acetoin utilization protein
LXH20_RS13940	COG1360	Flagellar Motor Protein
LXH20_RS13945	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LXH20_RS13950	COG1609	Transcriptional regulator
LXH20_RS13955	COG1605	Chorismate mutase
LXH20_RS13955	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LXH20_RS13960	COG3118	belongs to the thioredoxin family
LXH20_RS13965	COG4980	gas vesicle protein
LXH20_RS13970	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LXH20_RS13980	COG1674	ftsk spoiiie
LXH20_RS13985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXH20_RS13995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXH20_RS14005	COG1363	Peptidase, m42
LXH20_RS14010	COG5584	Small secreted protein
LXH20_RS14015	COG0281	malic enzyme
LXH20_RS14020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXH20_RS14035	COG0510	thiamine kinase activity
LXH20_RS14040	COG1597	lipid kinase activity
LXH20_RS14050	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LXH20_RS14055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LXH20_RS14060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LXH20_RS14065	COG2252	PERMEase
LXH20_RS14070	COG4473	ABC transporter
LXH20_RS14075	COG1131	(ABC) transporter
LXH20_RS14080	COG1349	DNA-binding transcription factor activity
LXH20_RS14085	COG1187	pseudouridine synthase activity
LXH20_RS14090	COG2244	polysaccharide biosynthetic process
LXH20_RS14095	COG2081	HI0933 family
LXH20_RS14100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LXH20_RS14110	COG1609	Transcriptional regulator
LXH20_RS14115	COG1653	transport
LXH20_RS14120	COG1175	transmembrane transport
LXH20_RS14125	COG0395	ABC-type sugar transport system, permease component
LXH20_RS14130	COG1486	melibiose metabolic process
LXH20_RS14140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LXH20_RS14155	COG1366	Belongs to the anti-sigma-factor antagonist family
LXH20_RS14155	COG2202	Pas domain
LXH20_RS14160	COG2814	Major facilitator Superfamily
LXH20_RS14165	COG5522	Integral membrane protein (intg_mem_TP0381)
LXH20_RS14170	COG0577	efflux transmembrane transporter activity
LXH20_RS14175	COG1136	(ABC) transporter
LXH20_RS14180	COG2205	protein histidine kinase activity
LXH20_RS14185	COG0745	RESPONSE REGULATOR receiver
LXH20_RS14190	COG0577	efflux transmembrane transporter activity
LXH20_RS14195	COG1136	(ABC) transporter
LXH20_RS14215	COG1131	(ABC) transporter
LXH20_RS14220	COG1725	Transcriptional regulator
LXH20_RS14235	COG1242	4 iron, 4 sulfur cluster binding
LXH20_RS14240	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LXH20_RS14250	COG0584	glycerophosphoryl diester phosphodiesterase
LXH20_RS14260	COG2267	carboxylic ester hydrolase activity
LXH20_RS14265	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LXH20_RS14270	COG1113	amino acid transport
LXH20_RS14275	COG0367	asparagine synthase
LXH20_RS14295	COG1506	peptidase
LXH20_RS14300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXH20_RS14305	COG1116	anion transmembrane transporter activity
LXH20_RS14310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXH20_RS14315	COG0494	nUDIX hydrolase
LXH20_RS14320	COG4824	toxin secretion phage lysis holin
LXH20_RS14325	COG0783	Belongs to the Dps family
LXH20_RS14350	COG0288	reversible hydration of carbon dioxide
LXH20_RS14360	COG1271	oxidase subunit
LXH20_RS14365	COG1294	oxidase, subunit
LXH20_RS14375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LXH20_RS14380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LXH20_RS14380	COG1321	iron dependent repressor
LXH20_RS14385	COG1121	(ABC) transporter
LXH20_RS14390	COG0803	Belongs to the bacterial solute-binding protein 9 family
LXH20_RS14395	COG4948	Mandelate Racemase Muconate Lactonizing
LXH20_RS14405	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LXH20_RS14410	COG0596	Alpha beta hydrolase
LXH20_RS14420	COG1169	isochorismate synthase
LXH20_RS14425	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LXH20_RS14430	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LXH20_RS14555	COG3859	Proton-coupled thiamine transporter YuaJ
LXH20_RS14560	COG2268	Band 7 protein
LXH20_RS14565	COG1585	Membrane protein implicated in regulation of membrane protease activity
LXH20_RS14570	COG2318	DinB family
LXH20_RS14580	COG1454	alcohol dehydrogenase
LXH20_RS14585	COG1012	belongs to the aldehyde dehydrogenase family
LXH20_RS14590	COG1510	regulation of RNA biosynthetic process
LXH20_RS14600	COG0569	domain protein
LXH20_RS14605	COG1705	Flagellar rod assembly protein muramidase FlgJ
LXH20_RS14610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LXH20_RS14610	COG1017	nitric oxide dioxygenase activity
LXH20_RS14635	COG0628	permease
LXH20_RS14640	COG0673	inositol 2-dehydrogenase activity
LXH20_RS14645	COG0693	protein deglycase activity
LXH20_RS14650	COG0840	transmembrane signaling receptor activity
LXH20_RS14655	COG0840	transmembrane signaling receptor activity
LXH20_RS14660	COG0840	transmembrane signaling receptor activity
LXH20_RS14665	COG0840	transmembrane signaling receptor activity
LXH20_RS14680	COG2070	2-Nitropropane dioxygenase
LXH20_RS14685	COG0432	Pfam Uncharacterised protein family UPF0047
LXH20_RS14690	COG0366	Alpha amylase catalytic
LXH20_RS14695	COG1253	flavin adenine dinucleotide binding
LXH20_RS14700	COG2738	Putative neutral zinc metallopeptidase
LXH20_RS14715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LXH20_RS14740	COG1335	isochorismatase
LXH20_RS14745	COG1979	alcohol dehydrogenase
LXH20_RS14750	COG1979	alcohol dehydrogenase
LXH20_RS14755	COG2155	Conserved Protein
LXH20_RS14760	COG1098	S1 RNA binding domain
LXH20_RS14765	COG0436	Aminotransferase
LXH20_RS14770	COG1522	sequence-specific DNA binding
LXH20_RS14775	COG2267	carboxylic ester hydrolase activity
LXH20_RS14785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LXH20_RS14790	COG2205	protein histidine kinase activity
LXH20_RS14800	COG5018	Exonuclease
LXH20_RS14805	COG2814	Major facilitator Superfamily
LXH20_RS14810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXH20_RS14815	COG3011	Protein conserved in bacteria
LXH20_RS14825	COG3290	protein histidine kinase activity
LXH20_RS14830	COG4565	transcriptional regulatory protein
LXH20_RS14835	COG1744	ABC transporter substrate-binding protein PnrA-like
LXH20_RS14840	COG3845	ABC transporter
LXH20_RS14845	COG4603	Belongs to the binding-protein-dependent transport system permease family
LXH20_RS14850	COG1079	Belongs to the binding-protein-dependent transport system permease family
LXH20_RS14860	COG2111	Na H antiporter
LXH20_RS14860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LXH20_RS14865	COG2111	Na H antiporter
LXH20_RS14870	COG1006	Multisubunit Na H antiporter MnhC subunit
LXH20_RS14875	COG0651	ATP synthesis coupled electron transport
LXH20_RS14880	COG1863	multisubunit Na H antiporter MnhE subunit
LXH20_RS14885	COG2212	antiporter activity
LXH20_RS14890	COG1320	monovalent cation:proton antiporter activity
LXH20_RS14895	COG2050	protein possibly involved in aromatic compounds catabolism
LXH20_RS14900	COG2197	response regulator
LXH20_RS14905	COG4585	Histidine kinase
LXH20_RS14915	COG0142	geranyltranstransferase activity
LXH20_RS14930	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LXH20_RS14935	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LXH20_RS14940	COG1335	isochorismatase
LXH20_RS14945	COG5506	Protein of unknown function (DUF1694)
LXH20_RS14960	COG0628	permease
LXH20_RS14970	COG1418	mRNA catabolic process
LXH20_RS14975	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS14985	COG1511	domain protein
LXH20_RS14990	COG0433	COG0433 Predicted ATPase
LXH20_RS14990	COG1674	ftsk spoiiie
LXH20_RS14995	COG4499	WXG100 protein secretion system (Wss), protein YukC
LXH20_RS15000	COG5417	Belongs to the EsaB family
LXH20_RS15005	COG4842	Belongs to the WXG100 family
LXH20_RS15010	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LXH20_RS15010	COG2508	Transcriptional regulator
LXH20_RS15015	COG0686	Belongs to the AlaDH PNT family
LXH20_RS15020	COG5634	Uncharacterized conserved protein (DUF2278)
LXH20_RS15025	COG3251	PFAM MbtH domain protein
LXH20_RS15030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXH20_RS15035	COG1535	isochorismatase
LXH20_RS15035	COG3433	isochorismatase activity
LXH20_RS15040	COG1021	2,3-dihydroxybenzoate-AMP ligase
LXH20_RS15045	COG1169	isochorismate synthase
LXH20_RS15050	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS15055	COG2819	hydrolase of the alpha beta superfamily
LXH20_RS15060	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LXH20_RS15065	COG1268	BioY protein
LXH20_RS15070	COG2056	Na+-H+ antiporter family
LXH20_RS15080	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LXH20_RS15085	COG3584	3D domain protein
LXH20_RS15100	COG1252	NADH dehydrogenase
LXH20_RS15130	COG1131	(ABC) transporter
LXH20_RS15150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXH20_RS15155	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LXH20_RS15160	COG0316	Belongs to the HesB IscA family
LXH20_RS15170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LXH20_RS15180	COG1252	NADH dehydrogenase
LXH20_RS15185	COG4837	Protein of unknown function (DUF1462)
LXH20_RS15190	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LXH20_RS15195	COG4946	Tricorn protease homolog
LXH20_RS15195	COG1506	peptidase
LXH20_RS15195	COG0823	Involved in the tonB-independent uptake of proteins
LXH20_RS15205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LXH20_RS15210	COG0460	homoserine dehydrogenase
LXH20_RS15215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LXH20_RS15220	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LXH20_RS15225	COG0647	UMP catabolic process
LXH20_RS15230	COG2445	Protein of unknown function DUF86
LXH20_RS15235	COG4470	Protein conserved in bacteria
LXH20_RS15245	COG0739	heme binding
LXH20_RS15255	COG0737	Belongs to the 5'-nucleotidase family
LXH20_RS15260	COG0730	response to heat
LXH20_RS15265	COG1801	Protein of unknown function DUF72
LXH20_RS15280	COG2508	Transcriptional regulator
LXH20_RS15285	COG0457	Tetratricopeptide repeat
LXH20_RS15300	COG2814	Major facilitator Superfamily
LXH20_RS15305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LXH20_RS15310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LXH20_RS15315	COG2356	endonuclease I
LXH20_RS15320	COG3842	ATPase activity
LXH20_RS15325	COG2188	Transcriptional regulator
LXH20_RS15330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXH20_RS15335	COG0395	ABC-type sugar transport system, permease component
LXH20_RS15340	COG1175	transmembrane transport
LXH20_RS15345	COG1653	transport
LXH20_RS15350	COG2222	sugar isomerase
LXH20_RS15355	COG0789	Transcriptional regulator
LXH20_RS15380	COG0322	excinuclease ABC activity
LXH20_RS15385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LXH20_RS15405	COG3409	Peptidoglycan-binding domain 1 protein
LXH20_RS15410	COG0719	Fe-S assembly protein
LXH20_RS15415	COG0822	iron-sulfur transferase activity
LXH20_RS15420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LXH20_RS15425	COG0719	Fe-S assembly protein
LXH20_RS15430	COG0396	ATPase activity
LXH20_RS15440	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LXH20_RS15445	COG1464	Belongs to the NlpA lipoprotein family
LXH20_RS15450	COG2011	ABC-type metal ion transport system permease component
LXH20_RS15455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LXH20_RS15465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXH20_RS15470	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LXH20_RS15485	COG1393	Belongs to the ArsC family
LXH20_RS15490	COG1960	acyl-CoA dehydrogenase activity
LXH20_RS15495	COG0183	Belongs to the thiolase family
LXH20_RS15500	COG1024	Enoyl-CoA hydratase
LXH20_RS15500	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXH20_RS15520	COG5577	PFAM Coat F domain
LXH20_RS15525	COG1846	Transcriptional regulator
LXH20_RS15530	COG0477	Major facilitator Superfamily
LXH20_RS15535	COG0583	DNA-binding transcription factor activity
LXH20_RS15555	COG1120	ATPase activity
LXH20_RS15570	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS15575	COG0783	Belongs to the Dps family
LXH20_RS15580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXH20_RS15585	COG0745	RESPONSE REGULATOR receiver
LXH20_RS15590	COG2205	protein histidine kinase activity
LXH20_RS15590	COG2770	Histidine kinase
LXH20_RS15600	COG1309	transcriptional regulator
LXH20_RS15605	COG0114	fumarate hydratase activity
LXH20_RS15615	COG0697	spore germination
LXH20_RS15620	COG0814	amino acid
LXH20_RS15630	COG2197	response regulator
LXH20_RS15635	COG4585	Histidine kinase
LXH20_RS15640	COG4758	membrane
LXH20_RS15645	COG3595	metallopeptidase activity
LXH20_RS15650	COG1842	Phage shock protein A
LXH20_RS15655	COG4758	membrane
LXH20_RS15660	COG2814	Major facilitator Superfamily
LXH20_RS15665	COG2096	Adenosyltransferase
LXH20_RS15670	COG1120	ATPase activity
LXH20_RS15675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXH20_RS15680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXH20_RS15685	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS15690	COG3386	PFAM SMP-30 Gluconolaconase
LXH20_RS15695	COG2205	protein histidine kinase activity
LXH20_RS15700	COG0745	RESPONSE REGULATOR receiver
LXH20_RS15710	COG1191	sigma factor activity
LXH20_RS15720	COG2140	Oxalate decarboxylase
LXH20_RS15730	COG1120	ATPase activity
LXH20_RS15735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXH20_RS15740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXH20_RS15745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXH20_RS15775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXH20_RS15780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LXH20_RS15800	COG0492	ferredoxin-NADP+ reductase activity
LXH20_RS15805	COG3118	belongs to the thioredoxin family
LXH20_RS15815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXH20_RS15835	COG1309	transcriptional regulator
LXH20_RS15840	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LXH20_RS15845	COG0531	amino acid
LXH20_RS15855	COG1988	membrane-bound metal-dependent
LXH20_RS15860	COG1368	sulfuric ester hydrolase activity
LXH20_RS15865	COG1910	domain protein
LXH20_RS15870	COG0725	ABC transporter, periplasmic molybdate-binding protein
LXH20_RS15875	COG4149	molybdate abc transporter
LXH20_RS15880	COG2197	response regulator
LXH20_RS15885	COG3850	Histidine kinase
LXH20_RS15890	COG1131	(ABC) transporter
LXH20_RS15900	COG0842	Transport permease protein
LXH20_RS15905	COG0656	L-ascorbic acid biosynthetic process
LXH20_RS15925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LXH20_RS15930	COG3973	AAA domain
LXH20_RS15935	COG2860	membrane
LXH20_RS15945	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LXH20_RS15950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LXH20_RS15955	COG2217	Heavy metal translocating P-type atpase
LXH20_RS15960	COG2217	Heavy metal translocating P-type atpase
LXH20_RS15965	COG2608	mercury ion transmembrane transporter activity
LXH20_RS15970	COG1937	Protein conserved in bacteria
LXH20_RS15975	COG0673	inositol 2-dehydrogenase activity
LXH20_RS15985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXH20_RS15990	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LXH20_RS15995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXH20_RS16000	COG1126	abc transporter atp-binding protein
LXH20_RS16005	COG0765	amino acid transport
LXH20_RS16010	COG0765	amino acid transport
LXH20_RS16015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXH20_RS16020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXH20_RS16025	COG0454	-acetyltransferase
LXH20_RS16030	COG0583	DNA-binding transcription factor activity
LXH20_RS16035	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS16040	COG2732	(Barnase) inhibitor
LXH20_RS16045	COG2732	(Barnase) inhibitor
LXH20_RS16060	COG0557	exoribonuclease II activity
LXH20_RS16065	COG1647	Serine aminopeptidase, S33
LXH20_RS16070	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LXH20_RS16075	COG1476	TRANSCRIPTIONal
LXH20_RS16080	COG1396	sequence-specific DNA binding
LXH20_RS16085	COG1396	sequence-specific DNA binding
LXH20_RS16090	COG1733	regulation of RNA biosynthetic process
LXH20_RS16115	COG1131	(ABC) transporter
LXH20_RS16120	COG1174	glycine betaine transport
LXH20_RS16125	COG1732	Glycine betaine
LXH20_RS16130	COG1174	glycine betaine transport
LXH20_RS16135	COG1125	glycine betaine transport
LXH20_RS16135	COG0517	IMP dehydrogenase activity
LXH20_RS16140	COG1510	regulation of RNA biosynthetic process
LXH20_RS16145	COG1174	glycine betaine transport
LXH20_RS16150	COG1732	Glycine betaine
LXH20_RS16155	COG1174	glycine betaine transport
LXH20_RS16160	COG0517	IMP dehydrogenase activity
LXH20_RS16160	COG1125	glycine betaine transport
LXH20_RS16165	COG1510	regulation of RNA biosynthetic process
LXH20_RS16170	COG2095	MarC family integral membrane protein
LXH20_RS16175	COG3064	Membrane
LXH20_RS16180	COG4640	response to antibiotic
LXH20_RS16185	COG0456	acetyltransferase
LXH20_RS16205	COG0126	phosphoglycerate kinase activity
LXH20_RS16210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LXH20_RS16215	COG2390	Transcriptional regulator
LXH20_RS16220	COG2814	Major facilitator Superfamily
LXH20_RS16225	COG1609	Transcriptional regulator
LXH20_RS16230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXH20_RS16235	COG0583	DNA-binding transcription factor activity
LXH20_RS16240	COG0697	spore germination
LXH20_RS16245	COG1113	amino acid transport
LXH20_RS16255	COG1737	Transcriptional regulator
LXH20_RS16260	COG1070	Carbohydrate kinase
LXH20_RS16285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXH20_RS16290	COG2186	Transcriptional regulator
LXH20_RS16295	COG1620	l-lactate permease
LXH20_RS16300	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LXH20_RS16310	COG5039	Polysaccharide pyruvyl transferase
LXH20_RS16315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LXH20_RS16320	COG0110	maltose O-acetyltransferase activity
LXH20_RS16325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LXH20_RS16330	COG2244	polysaccharide biosynthetic process
LXH20_RS16335	COG1216	Glycosyl transferase, family 2
LXH20_RS16340	COG5039	Polysaccharide pyruvyl transferase
LXH20_RS16345	COG1216	Glycosyl transferase, family 2
LXH20_RS16355	COG0438	transferase activity, transferring glycosyl groups
LXH20_RS16360	COG1215	transferase activity, transferring glycosyl groups
LXH20_RS16365	COG0438	transferase activity, transferring glycosyl groups
LXH20_RS16370	COG1086	Polysaccharide biosynthesis protein
LXH20_RS16375	COG0489	protein tyrosine kinase activity
LXH20_RS16380	COG3944	biosynthesis protein
LXH20_RS16385	COG1396	sequence-specific DNA binding
LXH20_RS16390	COG2272	Belongs to the type-B carboxylesterase lipase family
LXH20_RS16400	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LXH20_RS16405	COG2364	Membrane
LXH20_RS16410	COG0456	acetyltransferase
LXH20_RS16415	COG3479	Phenolic acid decarboxylase
LXH20_RS16470	COG2223	nitrite transmembrane transporter activity
LXH20_RS16475	COG1609	Transcriptional regulator
LXH20_RS16485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LXH20_RS16490	COG0366	Alpha amylase catalytic
LXH20_RS16495	COG1554	hydrolase, family 65, central catalytic
LXH20_RS16500	COG5521	maltodextrose utilization protein MalA
LXH20_RS16505	COG3833	ABC-type maltose transport systems, permease component
LXH20_RS16510	COG1175	transmembrane transport
LXH20_RS16515	COG2182	Extracellular solute-binding protein
LXH20_RS16520	COG0366	Alpha amylase catalytic
LXH20_RS16525	COG1609	Transcriptional regulator
LXH20_RS16530	COG1611	Belongs to the LOG family
LXH20_RS16535	COG1694	Mazg nucleotide pyrophosphohydrolase
LXH20_RS16540	COG0659	secondary active sulfate transmembrane transporter activity
LXH20_RS16545	COG0288	reversible hydration of carbon dioxide
LXH20_RS16550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LXH20_RS16555	COG4290	ribonuclease
LXH20_RS16560	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LXH20_RS16565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXH20_RS16575	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LXH20_RS16585	COG1051	belongs to the nudix hydrolase family
LXH20_RS16590	COG0492	ferredoxin-NADP+ reductase activity
LXH20_RS16595	COG0791	NLP P60 protein
LXH20_RS16595	COG3883	PFAM NLP P60 protein
LXH20_RS16600	COG0457	Tetratricopeptide repeat
LXH20_RS16605	COG5002	protein histidine kinase activity
LXH20_RS16610	COG0745	RESPONSE REGULATOR receiver
LXH20_RS16620	COG1132	(ABC) transporter
LXH20_RS16625	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LXH20_RS16625	COG0140	phosphoribosyl-ATP diphosphatase activity
LXH20_RS16650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LXH20_RS16665	COG4990	cell redox homeostasis
LXH20_RS16670	COG0110	maltose O-acetyltransferase activity
LXH20_RS16690	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LXH20_RS16700	COG2188	Transcriptional regulator
LXH20_RS16705	COG1309	transcriptional regulator
LXH20_RS16710	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LXH20_RS16715	COG1950	PFAM Membrane protein of
LXH20_RS16720	COG1983	PspC domain protein
LXH20_RS16725	COG3595	metallopeptidase activity
LXH20_RS16740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LXH20_RS16750	COG4897	Protein conserved in bacteria
LXH20_RS16755	COG3848	Pyruvate phosphate dikinase
LXH20_RS16755	COG0574	Belongs to the PEP-utilizing enzyme family
LXH20_RS16760	COG1309	transcriptional regulator
LXH20_RS16765	COG2814	Major facilitator Superfamily
LXH20_RS16800	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS16810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXH20_RS16820	COG0793	Belongs to the peptidase S41A family
LXH20_RS16820	COG3409	Peptidoglycan-binding domain 1 protein
LXH20_RS16825	COG3420	alginic acid biosynthetic process
LXH20_RS16830	COG2177	Part of the ABC transporter FtsEX involved in
LXH20_RS16835	COG2884	Cell division ATP-binding protein ftsE
LXH20_RS16840	COG2010	Cytochrome c
LXH20_RS16845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXH20_RS16860	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LXH20_RS16875	COG1516	flagellar protein fliS
LXH20_RS16880	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LXH20_RS16885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LXH20_RS16905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LXH20_RS16910	COG1256	bacterial-type flagellum assembly
LXH20_RS16910	COG4786	Flagellar basal body rod
LXH20_RS16915	COG3418	PFAM FlgN family protein
LXH20_RS16920	COG2747	anti-sigma28 factor FlgM
LXH20_RS16930	COG1040	competence protein
LXH20_RS16940	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LXH20_RS16945	COG1307	EDD domain protein, DegV family
LXH20_RS16950	COG2197	response regulator
LXH20_RS16955	COG4585	Histidine kinase
LXH20_RS16960	COG1739	Uncharacterized protein family UPF0029
LXH20_RS16965	COG1316	TRANSCRIPTIONal
LXH20_RS16970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LXH20_RS16975	COG0438	transferase activity, transferring glycosyl groups
LXH20_RS16980	COG1215	transferase activity, transferring glycosyl groups
LXH20_RS16985	COG3206	protein involved in exopolysaccharide biosynthesis
LXH20_RS16990	COG3307	-O-antigen
LXH20_RS16995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LXH20_RS17000	COG0297	glycogen (starch) synthase activity
LXH20_RS17000	COG0438	transferase activity, transferring glycosyl groups
LXH20_RS17005	COG2244	polysaccharide biosynthetic process
LXH20_RS17015	COG2247	cell wall binding repeat
LXH20_RS17015	COG0860	N-Acetylmuramoyl-L-alanine amidase
LXH20_RS17020	COG2385	sporulation resulting in formation of a cellular spore
LXH20_RS17020	COG2247	cell wall binding repeat
LXH20_RS17030	COG1316	TRANSCRIPTIONal
LXH20_RS17035	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LXH20_RS17040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LXH20_RS17045	COG1134	teichoic acid transport
LXH20_RS17050	COG1682	transport, permease protein
LXH20_RS17055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LXH20_RS17065	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LXH20_RS17070	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LXH20_RS17075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LXH20_RS17080	COG4193	domain, Protein
LXH20_RS17085	COG1482	cell wall glycoprotein biosynthetic process
LXH20_RS17090	COG0697	spore germination
LXH20_RS17095	COG0814	amino acid
LXH20_RS17105	COG1215	transferase activity, transferring glycosyl groups
LXH20_RS17110	COG2814	Major facilitator Superfamily
LXH20_RS17115	COG1316	TRANSCRIPTIONal
LXH20_RS17120	COG0561	phosphatase activity
LXH20_RS17125	COG2433	Pfam Transposase IS66
LXH20_RS17130	COG0791	NLP P60 protein
LXH20_RS17140	COG2843	Capsule synthesis protein
LXH20_RS17150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LXH20_RS17155	COG0697	spore germination
LXH20_RS17160	COG0814	amino acid
LXH20_RS17170	COG1609	Transcriptional regulator
LXH20_RS17175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXH20_RS17185	COG1129	ABC transporter
LXH20_RS17190	COG1172	Belongs to the binding-protein-dependent transport system permease family
LXH20_RS17195	COG1879	ABC-type sugar transport system periplasmic component
LXH20_RS17200	COG3103	Sh3 type 3 domain protein
LXH20_RS17205	COG2249	NAD(P)H dehydrogenase (quinone) activity
LXH20_RS17210	COG3527	Alpha-acetolactate decarboxylase
LXH20_RS17215	COG0028	Belongs to the TPP enzyme family
LXH20_RS17220	COG0583	DNA-binding transcription factor activity
LXH20_RS17225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LXH20_RS17240	COG5337	Spore coat protein CotH
LXH20_RS17250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXH20_RS17260	COG0405	Gamma-glutamyltransferase
LXH20_RS17265	COG1522	sequence-specific DNA binding
LXH20_RS17270	COG2059	Chromate
LXH20_RS17275	COG2059	Chromate
LXH20_RS17285	COG0655	NAD(P)H dehydrogenase (quinone) activity
LXH20_RS17290	COG0583	DNA-binding transcription factor activity
LXH20_RS17315	COG5444	nuclease activity
LXH20_RS17330	COG3878	Protein conserved in bacteria
LXH20_RS17335	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LXH20_RS17340	COG4464	protein tyrosine phosphatase activity
LXH20_RS17345	COG0489	protein tyrosine kinase activity
LXH20_RS17350	COG3944	biosynthesis protein
LXH20_RS17360	COG4715	Zinc finger, swim domain protein
LXH20_RS17365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LXH20_RS17370	COG0561	phosphatase activity
LXH20_RS17375	COG1349	DNA-binding transcription factor activity
LXH20_RS17380	COG0629	single-stranded DNA binding
LXH20_RS17405	COG0457	Tetratricopeptide repeat
LXH20_RS17410	COG4786	Flagellar basal body rod
LXH20_RS17415	COG4786	Flagellar basal body rod
LXH20_RS17420	COG1077	Cell shape determining protein MreB Mrl
LXH20_RS17425	COG1609	Transcriptional regulator
LXH20_RS17430	COG1846	Transcriptional regulator
LXH20_RS17435	COG2814	Major facilitator Superfamily
LXH20_RS17440	COG1953	Uracil, thiamine, allantoin
LXH20_RS17445	COG0477	Major facilitator Superfamily
LXH20_RS17450	COG1335	isochorismatase
LXH20_RS17455	COG0004	ammonium transporteR
LXH20_RS17460	COG0347	Belongs to the P(II) protein family
LXH20_RS17465	COG0772	Belongs to the SEDS family
LXH20_RS17470	COG0671	phosphoesterase, PA-phosphatase related
LXH20_RS17480	COG0739	heme binding
LXH20_RS17485	COG1247	-acetyltransferase
LXH20_RS17500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LXH20_RS17510	COG0726	polysaccharide deacetylase
LXH20_RS17515	COG1959	2 iron, 2 sulfur cluster binding
LXH20_RS17530	COG0831	urea catabolic process
LXH20_RS17540	COG1994	Peptidase M50
LXH20_RS17545	COG0457	Tetratricopeptide repeat
LXH20_RS17555	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LXH20_RS17565	COG2304	oxidoreductase activity
LXH20_RS17570	COG2304	oxidoreductase activity
LXH20_RS17575	COG2385	sporulation resulting in formation of a cellular spore
LXH20_RS17580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LXH20_RS17590	COG4836	Membrane
LXH20_RS17660	COG0698	ribose 5-phosphate isomerase
LXH20_RS17665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LXH20_RS17675	COG0009	L-threonylcarbamoyladenylate synthase
LXH20_RS17680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LXH20_RS17700	COG2890	protein-(glutamine-N5) methyltransferase activity
LXH20_RS17705	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LXH20_RS17710	COG0346	lactoylglutathione lyase activity
LXH20_RS17715	COG0789	Transcriptional regulator
LXH20_RS17720	COG0679	Auxin Efflux Carrier
LXH20_RS17725	COG0281	malic enzyme
LXH20_RS17740	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LXH20_RS17750	COG1494	fructose-1,6-bisphosphatase
LXH20_RS17755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LXH20_RS17765	COG0191	fructose-bisphosphate aldolase activity
LXH20_RS17770	COG2204	response regulator
LXH20_RS17775	COG4821	SIS domain
LXH20_RS17790	COG0247	lactate metabolic process
LXH20_RS17790	COG2181	nitrate reductase activity
LXH20_RS17795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LXH20_RS17810	COG1132	(ABC) transporter
LXH20_RS17815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LXH20_RS17825	COG2181	nitrate reductase activity
LXH20_RS17830	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LXH20_RS17835	COG1140	nitrate reductase beta subunit
LXH20_RS17840	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LXH20_RS17845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LXH20_RS17855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LXH20_RS17860	COG2223	nitrite transmembrane transporter activity
LXH20_RS17870	COG4506	Protein conserved in bacteria
LXH20_RS17875	COG0457	Tetratricopeptide repeat
LXH20_RS17915	COG0010	Belongs to the arginase family
LXH20_RS17920	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LXH20_RS17925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXH20_RS17940	COG1994	Peptidase M50
LXH20_RS17945	COG1942	4-Oxalocrotonate Tautomerase
LXH20_RS17950	COG1846	Transcriptional regulator
LXH20_RS17955	COG0531	amino acid
LXH20_RS17960	COG3465	dGTPase activity
LXH20_RS17965	COG1078	dGTPase activity
LXH20_RS17980	COG1695	Transcriptional regulator
LXH20_RS17990	COG1131	(ABC) transporter
LXH20_RS17995	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LXH20_RS18025	COG0583	DNA-binding transcription factor activity
LXH20_RS18030	COG2855	membrane
LXH20_RS18035	COG0280	phosphate acetyltransferase
LXH20_RS18045	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS18050	COG0436	Aminotransferase
LXH20_RS18080	COG2814	Major facilitator Superfamily
LXH20_RS18085	COG2814	Major facilitator Superfamily
LXH20_RS18090	COG0833	amino acid
LXH20_RS18095	COG4187	Peptidase family M20/M25/M40
LXH20_RS18100	COG1012	belongs to the aldehyde dehydrogenase family
LXH20_RS18105	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LXH20_RS18110	COG2205	protein histidine kinase activity
LXH20_RS18115	COG0745	RESPONSE REGULATOR receiver
LXH20_RS18130	COG1131	(ABC) transporter
LXH20_RS18135	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LXH20_RS18140	COG1091	dTDP-4-dehydrorhamnose reductase activity
LXH20_RS18145	COG1088	dTDP-glucose 4,6-dehydratase activity
LXH20_RS18150	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LXH20_RS18155	COG3980	spore coat polysaccharide biosynthesis protein
LXH20_RS18160	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
LXH20_RS18165	COG2089	acid synthase
LXH20_RS18170	COG0456	acetyltransferase
LXH20_RS18175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LXH20_RS18180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LXH20_RS18185	COG0463	Glycosyl transferase, family 2
LXH20_RS18195	COG2363	Small membrane protein
LXH20_RS18200	COG2233	PERMEase
LXH20_RS18215	COG1216	Glycosyl transferase, family 2
LXH20_RS18230	COG1695	Transcriptional regulator
LXH20_RS18235	COG0351	phosphomethylpyrimidine kinase
LXH20_RS18245	COG1621	beta-fructofuranosidase activity
LXH20_RS18250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXH20_RS18250	COG1263	PTS System
LXH20_RS18255	COG3711	transcriptional antiterminator
LXH20_RS18265	COG1404	Belongs to the peptidase S8 family
LXH20_RS18270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXH20_RS18275	COG0778	Nitroreductase
LXH20_RS18280	COG0772	Belongs to the SEDS family
LXH20_RS18285	COG0454	-acetyltransferase
LXH20_RS18305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LXH20_RS18310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LXH20_RS18315	COG2261	transglycosylase associated protein
LXH20_RS18320	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LXH20_RS18325	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LXH20_RS18330	COG2246	polysaccharide biosynthetic process
LXH20_RS18335	COG1309	transcriptional regulator
LXH20_RS18355	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LXH20_RS18360	COG2837	iron assimilation
LXH20_RS18380	COG0583	DNA-binding transcription factor activity
LXH20_RS18390	COG1346	cytolysis
LXH20_RS18395	COG4895	conserved protein (DUF2196)
LXH20_RS18400	COG0789	Transcriptional regulator
LXH20_RS18405	COG5504	Zn-dependent protease
LXH20_RS18410	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LXH20_RS18415	COG0346	lactoylglutathione lyase activity
LXH20_RS18420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXH20_RS18425	COG1404	Belongs to the peptidase S8 family
LXH20_RS18430	COG1442	glycosyl transferase family 8
LXH20_RS18435	COG1846	Transcriptional regulator
LXH20_RS18440	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LXH20_RS18445	COG2357	RelA SpoT domain protein
LXH20_RS18450	COG1575	Belongs to the MenA family. Type 1 subfamily
LXH20_RS18465	COG1696	Membrane protein involved in D-alanine export
LXH20_RS18475	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LXH20_RS18480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXH20_RS18485	COG1486	melibiose metabolic process
LXH20_RS18490	COG1447	Phosphotransferase system cellobiose-specific component IIA
LXH20_RS18495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXH20_RS18500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXH20_RS18505	COG3711	transcriptional antiterminator
LXH20_RS18505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXH20_RS18515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXH20_RS18520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXH20_RS18530	COG0640	Transcriptional regulator
LXH20_RS18535	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LXH20_RS18540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXH20_RS18545	COG1447	Phosphotransferase system cellobiose-specific component IIA
LXH20_RS18550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXH20_RS18555	COG2723	6-phospho-beta-galactosidase activity
LXH20_RS18560	COG1940	carbohydrate kinase activity
LXH20_RS18565	COG1482	cell wall glycoprotein biosynthetic process
LXH20_RS18575	COG0753	catalase activity
LXH20_RS18580	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LXH20_RS18585	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LXH20_RS18590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LXH20_RS18595	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LXH20_RS18600	COG4988	ABC transporter
LXH20_RS18605	COG1294	oxidase, subunit
LXH20_RS18610	COG1271	oxidase subunit
LXH20_RS18615	COG3493	citrate carrier protein
LXH20_RS18620	COG0726	polysaccharide deacetylase
LXH20_RS18625	COG3842	ATPase activity
LXH20_RS18630	COG2508	Transcriptional regulator
LXH20_RS18635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXH20_RS18645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LXH20_RS18660	COG4894	glucomannan catabolic process
LXH20_RS18665	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LXH20_RS18670	COG0500	methyltransferase
LXH20_RS18675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LXH20_RS18695	COG0753	catalase activity
LXH20_RS18695	COG0693	protein deglycase activity
LXH20_RS18700	COG2851	Citrate transporter
LXH20_RS18705	COG2273	Hydrolase Family 16
LXH20_RS18710	COG3711	transcriptional antiterminator
LXH20_RS18715	COG2270	Major facilitator Superfamily
LXH20_RS18720	COG0513	Belongs to the DEAD box helicase family
LXH20_RS18765	COG0697	spore germination
LXH20_RS18770	COG0589	response to stress
LXH20_RS18780	COG0494	nUDIX hydrolase
LXH20_RS18785	COG3507	Belongs to the glycosyl hydrolase 43 family
LXH20_RS18810	COG0010	Belongs to the arginase family
LXH20_RS18815	COG0833	amino acid
LXH20_RS18820	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LXH20_RS18825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LXH20_RS18835	COG2390	Transcriptional regulator
LXH20_RS18840	COG0561	phosphatase activity
LXH20_RS18870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXH20_RS18875	COG5294	Protein conserved in bacteria
LXH20_RS18880	COG0577	efflux transmembrane transporter activity
LXH20_RS18885	COG1136	(ABC) transporter
LXH20_RS18890	COG2205	protein histidine kinase activity
LXH20_RS18895	COG0745	RESPONSE REGULATOR receiver
LXH20_RS18900	COG2205	protein histidine kinase activity
LXH20_RS18905	COG0745	RESPONSE REGULATOR receiver
LXH20_RS18935	COG1082	Xylose isomerase domain protein TIM barrel
LXH20_RS18945	COG2814	Major facilitator Superfamily
LXH20_RS18975	COG1349	DNA-binding transcription factor activity
LXH20_RS18980	COG0667	Aldo Keto reductase
LXH20_RS18985	COG2814	Major facilitator Superfamily
LXH20_RS19000	COG1028	Short-chain dehydrogenase reductase Sdr
LXH20_RS19005	COG2197	response regulator
LXH20_RS19010	COG4585	Histidine kinase
LXH20_RS19015	COG3239	Fatty acid desaturase
LXH20_RS19020	COG1309	transcriptional regulator
LXH20_RS19025	COG1012	belongs to the aldehyde dehydrogenase family
LXH20_RS19030	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LXH20_RS19040	COG0640	Transcriptional regulator
LXH20_RS19045	COG2814	Major facilitator Superfamily
LXH20_RS19050	COG1714	RDD family
LXH20_RS19060	COG0501	Belongs to the peptidase M48B family
LXH20_RS19065	COG1715	Restriction endonuclease
LXH20_RS19070	COG0450	alkyl hydroperoxide reductase
LXH20_RS19075	COG3634	alkyl hydroperoxide reductase activity
LXH20_RS19080	COG3177	Filamentation induced by cAMP protein fic
LXH20_RS19085	COG1113	amino acid transport
LXH20_RS19095	COG2080	2 iron, 2 sulfur cluster binding
LXH20_RS19110	COG2068	MobA-Related Protein
LXH20_RS19115	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LXH20_RS19170	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LXH20_RS19175	COG0667	Aldo Keto reductase
LXH20_RS19180	COG0456	acetyltransferase
LXH20_RS19185	COG0457	Tetratricopeptide repeat
LXH20_RS19190	COG0010	Belongs to the arginase family
LXH20_RS19195	COG0833	amino acid
LXH20_RS19200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LXH20_RS19205	COG5658	integral membrane protein
LXH20_RS19210	COG0640	Transcriptional regulator
LXH20_RS19215	COG3829	transcription factor binding
LXH20_RS19225	COG0488	(ABC) transporter
LXH20_RS19240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LXH20_RS19245	COG3850	Histidine kinase
LXH20_RS19245	COG5002	protein histidine kinase activity
LXH20_RS19250	COG0745	RESPONSE REGULATOR receiver
LXH20_RS19260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXH20_RS19265	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LXH20_RS19270	COG4853	Protein conserved in bacteria
LXH20_RS19275	COG4863	YycH protein
LXH20_RS19280	COG5002	protein histidine kinase activity
LXH20_RS19285	COG0745	RESPONSE REGULATOR receiver
LXH20_RS19315	COG0346	lactoylglutathione lyase activity
LXH20_RS19320	COG0305	Participates in initiation and elongation during chromosome replication
LXH20_RS19335	COG3093	addiction module antidote protein HigA
LXH20_RS19340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LXH20_RS19345	COG0297	glycogen (starch) synthase activity
LXH20_RS19355	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LXH20_RS19360	COG0438	transferase activity, transferring glycosyl groups
LXH20_RS19370	COG2112	serine threonine protein kinase
LXH20_RS19380	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LXH20_RS19385	COG4241	membrane
LXH20_RS19395	COG5577	PFAM Coat F domain
LXH20_RS19400	COG1733	regulation of RNA biosynthetic process
LXH20_RS19410	COG0697	spore germination
LXH20_RS19415	COG1621	beta-fructofuranosidase activity
LXH20_RS19420	COG1621	beta-fructofuranosidase activity
LXH20_RS19425	COG1802	Transcriptional regulator
LXH20_RS19430	COG2318	DinB family
LXH20_RS19435	COG2211	Major facilitator Superfamily
LXH20_RS19440	COG0697	spore germination
LXH20_RS19450	COG0778	Nitroreductase
LXH20_RS19455	COG1846	Transcriptional regulator
LXH20_RS19460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXH20_RS19465	COG1846	Transcriptional regulator
LXH20_RS19470	COG2153	protein acetylation
LXH20_RS19480	COG0546	phosphoglycolate phosphatase activity
LXH20_RS19510	COG1404	Belongs to the peptidase S8 family
LXH20_RS19520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXH20_RS19525	COG0697	spore germination
LXH20_RS19530	COG1078	dGTPase activity
LXH20_RS19540	COG1331	Highly conserved protein containing a thioredoxin domain
LXH20_RS19545	COG1266	CAAX protease self-immunity
LXH20_RS19550	COG0477	Major facilitator Superfamily
LXH20_RS19550	COG2814	Major facilitator Superfamily
LXH20_RS19555	COG0346	lactoylglutathione lyase activity
LXH20_RS19560	COG1609	Transcriptional regulator
LXH20_RS19565	COG0708	Exodeoxyribonuclease III
LXH20_RS19575	COG0708	Exodeoxyribonuclease III
LXH20_RS19580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LXH20_RS19585	COG2169	Transcriptional regulator
LXH20_RS19595	COG0629	single-stranded DNA binding
LXH20_RS19605	COG0012	GTP binding
LXH20_RS19610	COG0243	molybdopterin cofactor binding
LXH20_RS19615	COG4481	Protein conserved in bacteria
LXH20_RS19620	COG3949	Membrane
LXH20_RS19635	COG1475	DNA binding
LXH20_RS19640	COG1192	Involved in chromosome partitioning
LXH20_RS19665	COG1847	R3H domain protein
LXH20_RS19670	COG0706	membrane insertase activity
LXH20_RS19735	COG1757	Na H antiporter