locus-tag	class	description
KV103_RS00010	COG0592	DNA-directed DNA polymerase activity
KV103_RS00015	COG2501	S4 domain
KV103_RS00030	COG0187	DNA topoisomerase II activity
KV103_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KV103_RS00070	COG0516	GMP reductase activity
KV103_RS00070	COG0517	IMP dehydrogenase activity
KV103_RS00075	COG1686	Belongs to the peptidase S11 family
KV103_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
KV103_RS00105	COG1428	Deoxynucleoside kinase
KV103_RS00110	COG1428	Deoxynucleoside kinase
KV103_RS00115	COG1388	LysM domain
KV103_RS00115	COG3858	chitin binding
KV103_RS00120	COG1335	isochorismatase
KV103_RS00125	COG0590	tRNA wobble adenosine to inosine editing
KV103_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KV103_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KV103_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KV103_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KV103_RS00195	COG3853	Toxic anion resistance protein (TelA)
KV103_RS00200	COG1982	Orn Lys Arg decarboxylase major
KV103_RS00210	COG3870	Protein conserved in bacteria
KV103_RS00215	COG1728	Protein conserved in bacteria
KV103_RS00220	COG0470	DNA polymerase III
KV103_RS00225	COG1774	PSP1 C-terminal conserved region
KV103_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KV103_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KV103_RS00250	COG2002	toxin-antitoxin pair type II binding
KV103_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KV103_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KV103_RS00260	COG0084	hydrolase, TatD family'
KV103_RS00265	COG3584	3D domain protein
KV103_RS00265	COG3583	domain protein
KV103_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KV103_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KV103_RS00285	COG4466	Protein conserved in bacteria
KV103_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KV103_RS00305	COG0251	oxidation-reduction process
KV103_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KV103_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KV103_RS00345	COG2002	toxin-antitoxin pair type II binding
KV103_RS00350	COG2244	polysaccharide biosynthetic process
KV103_RS00355	COG3956	TIGRFAM MazG family protein
KV103_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KV103_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KV103_RS00380	COG1098	S1 RNA binding domain
KV103_RS00395	COG2208	phosphoserine phosphatase activity
KV103_RS00400	COG2304	oxidoreductase activity
KV103_RS00405	COG0515	serine threonine protein kinase
KV103_RS00410	COG0037	tRNA processing
KV103_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KV103_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KV103_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KV103_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KV103_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KV103_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
KV103_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KV103_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KV103_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KV103_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KV103_RS00475	COG1396	sequence-specific DNA binding
KV103_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KV103_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KV103_RS00565	COG4463	regulation of RNA biosynthetic process
KV103_RS00570	COG3880	PFAM UvrB UvrC protein
KV103_RS00580	COG0542	response to heat
KV103_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KV103_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KV103_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
KV103_RS00615	COG1045	serine acetyltransferase
KV103_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KV103_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KV103_RS00635	COG3688	RNA-binding protein containing a PIN domain
KV103_RS00640	COG1595	DNA-templated transcription, initiation
KV103_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KV103_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
KV103_RS00680	COG2813	Specifically methylates the guanine in position
KV103_RS00695	COG1358	cellular component organization or biogenesis
KV103_RS00720	COG0596	Alpha beta hydrolase
KV103_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KV103_RS00830	COG0201	protein transport
KV103_RS00840	COG0024	Methionine aminopeptidase
KV103_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KV103_RS00875	COG1122	ATPase activity
KV103_RS00880	COG1122	ATPase activity
KV103_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KV103_RS00905	COG2226	methyltransferase
KV103_RS00910	COG2318	DinB family
KV103_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
KV103_RS00925	COG0489	protein tyrosine kinase activity
KV103_RS00935	COG2194	sulfuric ester hydrolase activity
KV103_RS00940	COG0726	polysaccharide deacetylase
KV103_RS01000	COG0738	Major facilitator superfamily
KV103_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KV103_RS01015	COG1063	alcohol dehydrogenase
KV103_RS01020	COG0659	secondary active sulfate transmembrane transporter activity
KV103_RS01025	COG0385	Bile acid
KV103_RS01030	COG2819	hydrolase of the alpha beta superfamily
KV103_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KV103_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KV103_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KV103_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KV103_RS01050	COG2207	Transcriptional regulator
KV103_RS01055	COG3876	Protein conserved in bacteria
KV103_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
KV103_RS01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KV103_RS01070	COG1263	PTS System
KV103_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KV103_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KV103_RS01085	COG1683	Conserved Protein
KV103_RS01115	COG1595	DNA-templated transcription, initiation
KV103_RS01120	COG5662	AntiSigma factor
KV103_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KV103_RS01130	COG4856	YbbR-like protein
KV103_RS01160	COG5002	protein histidine kinase activity
KV103_RS01165	COG1136	(ABC) transporter
KV103_RS01170	COG0577	efflux transmembrane transporter activity
KV103_RS01175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KV103_RS01190	COG1346	cytolysis
KV103_RS01195	COG1380	Effector of murein hydrolase LrgA
KV103_RS01200	COG1846	Transcriptional regulator
KV103_RS01205	COG1113	amino acid transport
KV103_RS01210	COG1011	Hydrolase
KV103_RS01215	COG4585	Histidine kinase
KV103_RS01220	COG2197	response regulator
KV103_RS01225	COG1131	(ABC) transporter
KV103_RS01265	COG0531	amino acid
KV103_RS01270	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KV103_RS01285	COG0584	glycerophosphoryl diester phosphodiesterase
KV103_RS01290	COG2271	Major facilitator Superfamily
KV103_RS01300	COG2368	4-hydroxyphenylacetate
KV103_RS01310	COG3409	Peptidoglycan-binding domain 1 protein
KV103_RS01325	COG1397	ADP-ribosylglycohydrolase
KV103_RS01330	COG5444	nuclease activity
KV103_RS01340	COG0371	Dehydrogenase
KV103_RS01350	COG1183	phosphatidylcholine synthase activity
KV103_RS01355	COG0586	Pfam SNARE associated Golgi protein
KV103_RS01360	COG0688	phosphatidylethanolamine metabolic process
KV103_RS01375	COG1301	dicarboxylic acid transport
KV103_RS01380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KV103_RS01385	COG0833	amino acid
KV103_RS01390	COG2040	homocysteine
KV103_RS01395	COG1115	amino acid carrier protein
KV103_RS01400	COG2066	Belongs to the glutaminase family
KV103_RS01405	COG4191	Histidine kinase
KV103_RS01410	COG0784	Response regulator, receiver
KV103_RS01430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KV103_RS01435	COG0778	Nitroreductase
KV103_RS01440	COG0346	lactoylglutathione lyase activity
KV103_RS01445	COG2259	Doxx family
KV103_RS01450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KV103_RS01465	COG3773	Cell wall hydrolase
KV103_RS01470	COG3540	Alkaline phosphatase
KV103_RS01475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KV103_RS01480	COG0805	protein transport
KV103_RS01490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KV103_RS01495	COG0477	Major facilitator Superfamily
KV103_RS01500	COG1309	transcriptional regulator
KV103_RS01505	COG0252	asparaginase activity
KV103_RS01510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KV103_RS01515	COG3012	SEC-C Motif Domain Protein
KV103_RS01515	COG1405	negative regulation of cell septum assembly
KV103_RS01530	COG1595	DNA-templated transcription, initiation
KV103_RS01535	COG1595	DNA-templated transcription, initiation
KV103_RS01540	COG1876	peptidase activity
KV103_RS01545	COG0457	Tetratricopeptide repeat
KV103_RS01550	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS01555	COG0366	Alpha amylase catalytic
KV103_RS01560	COG0803	Belongs to the bacterial solute-binding protein 9 family
KV103_RS01565	COG1121	(ABC) transporter
KV103_RS01570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KV103_RS01575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KV103_RS01580	COG2310	stress, protein
KV103_RS01585	COG2310	stress, protein
KV103_RS01590	COG2310	stress, protein
KV103_RS01595	COG0861	Integral membrane protein TerC family
KV103_RS01605	COG3853	Toxic anion resistance protein (TelA)
KV103_RS01610	COG0477	Major facilitator Superfamily
KV103_RS01615	COG4175	Glycine betaine
KV103_RS01615	COG0517	IMP dehydrogenase activity
KV103_RS01620	COG4176	ABC-type proline glycine betaine transport system permease component
KV103_RS01625	COG2113	Glycine betaine
KV103_RS01630	COG1473	amidohydrolase
KV103_RS01635	COG1288	antiporter activity
KV103_RS01655	COG2814	Major facilitator Superfamily
KV103_RS01660	COG1846	Transcriptional regulator
KV103_RS01665	COG1280	lysine exporter protein (LysE YggA)
KV103_RS01670	COG3403	YqcI/YcgG family
KV103_RS01675	COG1113	amino acid transport
KV103_RS01680	COG3665	Urea carboxylase-associated protein
KV103_RS01695	COG1660	Displays ATPase and GTPase activities
KV103_RS01700	COG1082	Xylose isomerase domain protein TIM barrel
KV103_RS01705	COG2271	Major facilitator Superfamily
KV103_RS01710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KV103_RS01715	COG3458	cephalosporin-C deacetylase activity
KV103_RS01720	COG3541	Predicted nucleotidyltransferase
KV103_RS01725	COG0506	proline dehydrogenase activity
KV103_RS01730	COG1012	belongs to the aldehyde dehydrogenase family
KV103_RS01735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KV103_RS01740	COG2508	Transcriptional regulator
KV103_RS01750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KV103_RS01750	COG1587	Uroporphyrinogen-III synthase
KV103_RS01755	COG2146	nitrite reductase [NAD(P)H] activity
KV103_RS01760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KV103_RS01765	COG0243	molybdopterin cofactor binding
KV103_RS01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KV103_RS01775	COG2223	nitrite transmembrane transporter activity
KV103_RS01780	COG0523	cobalamin synthesis protein
KV103_RS01785	COG1063	alcohol dehydrogenase
KV103_RS01790	COG1714	RDD family
KV103_RS01815	COG3209	COG3209 Rhs family protein
KV103_RS01820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KV103_RS01825	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KV103_RS01830	COG1733	regulation of RNA biosynthetic process
KV103_RS01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS01845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS01850	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KV103_RS01865	COG2364	Membrane
KV103_RS01870	COG1126	abc transporter atp-binding protein
KV103_RS01875	COG0765	amino acid transport
KV103_RS01885	COG0583	DNA-binding transcription factor activity
KV103_RS01890	COG0163	prenyltransferase activity
KV103_RS01895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KV103_RS01910	COG3104	oligopeptide transport
KV103_RS01915	COG5434	Belongs to the glycosyl hydrolase 28 family
KV103_RS01925	COG0697	spore germination
KV103_RS01935	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KV103_RS01940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KV103_RS01945	COG0456	acetyltransferase
KV103_RS01950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KV103_RS01955	COG0765	amino acid transport
KV103_RS01960	COG1126	abc transporter atp-binding protein
KV103_RS01965	COG1473	amidohydrolase
KV103_RS01970	COG2079	MmgE PrpD family protein
KV103_RS01975	COG1136	(ABC) transporter
KV103_RS01980	COG0577	efflux transmembrane transporter activity
KV103_RS01985	COG0745	RESPONSE REGULATOR receiver
KV103_RS01990	COG3850	Histidine kinase
KV103_RS01990	COG5002	protein histidine kinase activity
KV103_RS01995	COG0457	Tetratricopeptide repeat
KV103_RS02010	COG0527	aspartate kinase activity
KV103_RS02015	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KV103_RS02020	COG4605	iron ion homeostasis
KV103_RS02025	COG4604	ABC transporter, ATP-binding protein
KV103_RS02030	COG4607	ABC-type enterochelin transport system periplasmic component
KV103_RS02035	COG2814	Major facilitator Superfamily
KV103_RS02040	COG1309	transcriptional regulator
KV103_RS02045	COG0778	Nitroreductase
KV103_RS02050	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KV103_RS02055	COG0640	Transcriptional regulator
KV103_RS02060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KV103_RS02065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KV103_RS02070	COG1012	belongs to the aldehyde dehydrogenase family
KV103_RS02075	COG4975	Glucose uptake
KV103_RS02080	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS02085	COG4549	nuclear export factor GLE1
KV103_RS02090	COG2372	response to copper ion
KV103_RS02090	COG1276	copper resistance
KV103_RS02095	COG1349	DNA-binding transcription factor activity
KV103_RS02105	COG2213	PTS system mannitol-specific
KV103_RS02110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KV103_RS02120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KV103_RS02130	COG0561	phosphatase activity
KV103_RS02140	COG1914	H( )-stimulated, divalent metal cation uptake system
KV103_RS02150	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KV103_RS02155	COG1984	allophanate hydrolase subunit 2
KV103_RS02160	COG1414	Transcriptional regulator
KV103_RS02165	COG2755	lipolytic protein G-D-S-L family
KV103_RS02175	COG2329	Antibiotic biosynthesis monooxygenase
KV103_RS02180	COG0768	penicillin binding
KV103_RS02185	COG4989	oxidoreductase activity
KV103_RS02190	COG3711	transcriptional antiterminator
KV103_RS02195	COG0318	PFAM AMP-dependent synthetase and ligase
KV103_RS02200	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS02205	COG1917	Cupin 2, conserved barrel domain protein
KV103_RS02210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KV103_RS02215	COG3871	stress protein (general stress protein 26)
KV103_RS02225	COG2814	Major facilitator Superfamily
KV103_RS02230	COG1522	sequence-specific DNA binding
KV103_RS02235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KV103_RS02235	COG0551	DNA topoisomerase type I activity
KV103_RS02240	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KV103_RS02245	COG3706	GGDEF domain
KV103_RS02250	COG5298	Protein conserved in bacteria
KV103_RS02255	COG1215	transferase activity, transferring glycosyl groups
KV103_RS02265	COG0531	amino acid
KV103_RS02275	COG0028	Belongs to the TPP enzyme family
KV103_RS02300	COG0457	Tetratricopeptide repeat
KV103_RS02320	COG1914	H( )-stimulated, divalent metal cation uptake system
KV103_RS02340	COG2076	Multidrug Resistance protein
KV103_RS02345	COG2217	Heavy metal translocating P-type atpase
KV103_RS02350	COG3729	General stress protein
KV103_RS02355	COG0662	Cupin 2, conserved barrel domain protein
KV103_RS02360	COG2329	Antibiotic biosynthesis monooxygenase
KV103_RS02365	COG3546	catalase activity
KV103_RS02370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KV103_RS02375	COG3290	protein histidine kinase activity
KV103_RS02380	COG4565	transcriptional regulatory protein
KV103_RS02385	COG1301	dicarboxylic acid transport
KV103_RS02390	COG0628	permease
KV103_RS02395	COG1131	(ABC) transporter
KV103_RS02400	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KV103_RS02410	COG1960	acyl-CoA dehydrogenase activity
KV103_RS02425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KV103_RS02430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KV103_RS02440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KV103_RS02445	COG0513	Belongs to the DEAD box helicase family
KV103_RS02450	COG3402	PFAM membrane-flanked domain
KV103_RS02455	COG3428	Bacterial PH domain
KV103_RS02460	COG0705	Rhomboid family
KV103_RS02470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KV103_RS02475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KV103_RS02480	COG0864	Transcriptional regulator
KV103_RS02485	COG2337	Toxic component of a toxin-antitoxin (TA) module
KV103_RS02490	COG1366	Belongs to the anti-sigma-factor antagonist family
KV103_RS02495	COG1366	Belongs to the anti-sigma-factor antagonist family
KV103_RS02500	COG2172	sigma factor antagonist activity
KV103_RS02505	COG2208	phosphoserine phosphatase activity
KV103_RS02510	COG1366	Belongs to the anti-sigma-factor antagonist family
KV103_RS02520	COG1191	sigma factor activity
KV103_RS02525	COG2208	phosphoserine phosphatase activity
KV103_RS02530	COG2183	response to ionizing radiation
KV103_RS02595	COG5444	nuclease activity
KV103_RS02615	COG0477	Major facilitator Superfamily
KV103_RS02630	COG2030	dehydratase
KV103_RS02640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KV103_RS02645	COG1959	2 iron, 2 sulfur cluster binding
KV103_RS02650	COG2910	NAD(P)H-binding
KV103_RS02655	COG3239	Fatty acid desaturase
KV103_RS02665	COG1278	Cold shock
KV103_RS02670	COG1329	Transcriptional regulator
KV103_RS02675	COG1937	Protein conserved in bacteria
KV103_RS02680	COG2210	Belongs to the sulfur carrier protein TusA family
KV103_RS02685	COG1054	Belongs to the UPF0176 family
KV103_RS02690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KV103_RS02690	COG0425	Belongs to the sulfur carrier protein TusA family
KV103_RS02700	COG0425	Belongs to the sulfur carrier protein TusA family
KV103_RS02705	COG0730	response to heat
KV103_RS02710	COG1794	racemase activity, acting on amino acids and derivatives
KV103_RS02725	COG3621	Patatin-like phospholipase
KV103_RS02735	COG0662	Cupin 2, conserved barrel domain protein
KV103_RS02750	COG0277	FAD linked oxidase domain protein
KV103_RS02770	COG0662	Cupin 2, conserved barrel domain protein
KV103_RS02775	COG2318	DinB family
KV103_RS02810	COG1064	alcohol dehydrogenase
KV103_RS02815	COG0789	Transcriptional regulator
KV103_RS02825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KV103_RS02835	COG2814	Major facilitator Superfamily
KV103_RS02840	COG1309	transcriptional regulator
KV103_RS02845	COG0697	spore germination
KV103_RS02850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KV103_RS02855	COG5577	PFAM Coat F domain
KV103_RS02865	COG1063	alcohol dehydrogenase
KV103_RS02870	COG5577	PFAM Coat F domain
KV103_RS02880	COG4585	Histidine kinase
KV103_RS02885	COG2197	response regulator
KV103_RS02890	COG2409	Drug exporters of the RND superfamily
KV103_RS02895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KV103_RS02900	COG0488	(ABC) transporter
KV103_RS02905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KV103_RS02910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KV103_RS02920	COG2814	Major facilitator Superfamily
KV103_RS02925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KV103_RS02935	COG0730	response to heat
KV103_RS02940	COG0456	acetyltransferase
KV103_RS02945	COG0789	Transcriptional regulator
KV103_RS02945	COG4978	Transcriptional regulator
KV103_RS02950	COG0697	spore germination
KV103_RS02955	COG1051	belongs to the nudix hydrolase family
KV103_RS02960	COG2226	methyltransferase
KV103_RS02965	COG0473	3-isopropylmalate dehydrogenase activity
KV103_RS02970	COG1802	Transcriptional regulator
KV103_RS02975	COG1819	glycosyl
KV103_RS02990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KV103_RS03000	COG1388	LysM domain
KV103_RS03005	COG2814	Major facilitator Superfamily
KV103_RS03010	COG2188	Transcriptional regulator
KV103_RS03015	COG2186	Transcriptional regulator
KV103_RS03020	COG2807	transmembrane transport
KV103_RS03025	COG2076	Multidrug Resistance protein
KV103_RS03030	COG2076	Multidrug Resistance protein
KV103_RS03035	COG1309	transcriptional regulator
KV103_RS03040	COG0531	amino acid
KV103_RS03050	COG3832	glyoxalase III activity
KV103_RS03055	COG0604	alcohol dehydrogenase
KV103_RS03060	COG2814	Major facilitator Superfamily
KV103_RS03100	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KV103_RS03105	COG0802	atpase or kinase
KV103_RS03110	COG1214	PFAM Peptidase M22, glycoprotease
KV103_RS03115	COG0456	acetyltransferase
KV103_RS03120	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KV103_RS03125	COG0488	(ABC) transporter
KV103_RS03140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KV103_RS03145	COG0805	protein transport
KV103_RS03155	COG1266	CAAX protease self-immunity
KV103_RS03195	COG0457	Tetratricopeptide repeat
KV103_RS03200	COG1063	alcohol dehydrogenase
KV103_RS03205	COG2211	Major facilitator Superfamily
KV103_RS03210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KV103_RS03220	COG1842	Phage shock protein A
KV103_RS03225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KV103_RS03230	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KV103_RS03235	COG4260	virion core protein, lumpy skin disease virus
KV103_RS03240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KV103_RS03240	COG2755	lipolytic protein G-D-S-L family
KV103_RS03250	COG1595	DNA-templated transcription, initiation
KV103_RS03255	COG1063	alcohol dehydrogenase
KV103_RS03260	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KV103_RS03265	COG0823	Involved in the tonB-independent uptake of proteins
KV103_RS03275	COG2132	Multicopper oxidase
KV103_RS03280	COG1113	amino acid transport
KV103_RS03285	COG0714	Associated with various cellular activities
KV103_RS03290	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KV103_RS03295	COG1305	Transglutaminase-like
KV103_RS03320	COG2252	PERMEase
KV103_RS03325	COG3064	Membrane
KV103_RS03345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KV103_RS03350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KV103_RS03355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KV103_RS03360	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KV103_RS03365	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KV103_RS03380	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KV103_RS03390	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KV103_RS03395	COG0138	bifunctional purine biosynthesis protein purh
KV103_RS03400	COG0151	Belongs to the GarS family
KV103_RS03410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KV103_RS03415	COG1470	cell adhesion involved in biofilm formation
KV103_RS03420	COG4496	protein, YerC YecD
KV103_RS03425	COG0069	glutamate synthase activity
KV103_RS03435	COG0210	DNA helicase
KV103_RS03445	COG4851	CamS sex pheromone cAM373 precursor
KV103_RS03450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KV103_RS03455	COG1285	pathogenesis
KV103_RS03460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KV103_RS03480	COG1309	transcriptional regulator
KV103_RS03485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KV103_RS03490	COG1597	lipid kinase activity
KV103_RS03495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KV103_RS03505	COG1131	(ABC) transporter
KV103_RS03545	COG5444	nuclease activity
KV103_RS03575	COG3546	catalase activity
KV103_RS03580	COG0454	-acetyltransferase
KV103_RS03590	COG2323	membrane
KV103_RS03595	COG2329	Antibiotic biosynthesis monooxygenase
KV103_RS03600	COG0346	lactoylglutathione lyase activity
KV103_RS03605	COG1366	Belongs to the anti-sigma-factor antagonist family
KV103_RS03610	COG5583	Uncharacterized small protein (DUF2292)
KV103_RS03615	COG0196	riboflavin kinase activity
KV103_RS03620	COG0670	Belongs to the BI1 family
KV103_RS03625	COG1846	Transcriptional regulator
KV103_RS03630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KV103_RS03640	COG2124	cytochrome p450
KV103_RS03640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KV103_RS03645	COG1368	sulfuric ester hydrolase activity
KV103_RS03650	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KV103_RS03655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KV103_RS03660	COG1442	glycosyl transferase family 8
KV103_RS03665	COG1216	Glycosyl transferase, family 2
KV103_RS03670	COG1442	glycosyl transferase family 8
KV103_RS03675	COG2223	nitrite transmembrane transporter activity
KV103_RS03680	COG0531	amino acid
KV103_RS03685	COG1012	belongs to the aldehyde dehydrogenase family
KV103_RS03690	COG0840	transmembrane signaling receptor activity
KV103_RS03695	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS03700	COG0463	Glycosyl transferase, family 2
KV103_RS03700	COG0457	Tetratricopeptide repeat
KV103_RS03705	COG0488	(ABC) transporter
KV103_RS03710	COG0789	Transcriptional regulator
KV103_RS03715	COG2814	Major facilitator Superfamily
KV103_RS03720	COG0488	(ABC) transporter
KV103_RS03725	COG0513	Belongs to the DEAD box helicase family
KV103_RS03730	COG0456	acetyltransferase
KV103_RS03735	COG2130	NADP-dependent
KV103_RS03750	COG3866	Pectate lyase
KV103_RS03755	COG0471	metal ion transport
KV103_RS03775	COG3290	protein histidine kinase activity
KV103_RS03780	COG4565	transcriptional regulatory protein
KV103_RS03785	COG3181	Tripartite tricarboxylate transporter family receptor
KV103_RS03790	COG2851	Citrate transporter
KV103_RS03795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KV103_RS03800	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KV103_RS03810	COG2258	MOSC domain
KV103_RS03830	COG0024	Methionine aminopeptidase
KV103_RS03835	COG1263	PTS System
KV103_RS03835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KV103_RS03845	COG1368	sulfuric ester hydrolase activity
KV103_RS03855	COG0071	Belongs to the small heat shock protein (HSP20) family
KV103_RS03870	COG1263	PTS System
KV103_RS03870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KV103_RS03875	COG0366	Alpha amylase catalytic
KV103_RS03880	COG2188	Transcriptional regulator
KV103_RS03885	COG0778	Nitroreductase
KV103_RS03900	COG0737	Belongs to the 5'-nucleotidase family
KV103_RS03905	COG0693	protein deglycase activity
KV103_RS03910	COG1609	Transcriptional regulator
KV103_RS03925	COG2814	Major facilitator Superfamily
KV103_RS03935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KV103_RS03940	COG4980	gas vesicle protein
KV103_RS03945	COG1295	ribonuclease BN
KV103_RS03950	COG0477	Major facilitator Superfamily
KV103_RS03955	COG0387	Pfam Sodium calcium exchanger
KV103_RS03965	COG0668	transmembrane transport
KV103_RS03970	COG0535	radical SAM domain protein
KV103_RS03980	COG0726	polysaccharide deacetylase
KV103_RS04000	COG0745	RESPONSE REGULATOR receiver
KV103_RS04005	COG2205	protein histidine kinase activity
KV103_RS04010	COG2084	Dehydrogenase
KV103_RS04020	COG0598	Magnesium transport protein CorA
KV103_RS04025	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KV103_RS04030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KV103_RS04040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KV103_RS04045	COG4637	Psort location Cytoplasmic, score
KV103_RS04050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KV103_RS04055	COG0022	dehydrogenase e1 component
KV103_RS04060	COG0508	dehydrogenase complex catalyzes the overall conversion of
KV103_RS04065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KV103_RS04070	COG3284	Transcriptional regulator
KV103_RS04080	COG1486	melibiose metabolic process
KV103_RS04085	COG1737	Transcriptional regulator
KV103_RS04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KV103_RS04090	COG1263	PTS System
KV103_RS04100	COG1132	(ABC) transporter
KV103_RS04105	COG1132	(ABC) transporter
KV103_RS04110	COG2259	Doxx family
KV103_RS04115	COG2514	catechol 2,3-dioxygenase activity
KV103_RS04125	COG1695	Transcriptional regulator
KV103_RS04130	COG2249	NAD(P)H dehydrogenase (quinone) activity
KV103_RS04135	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KV103_RS04140	COG3848	Pyruvate phosphate dikinase
KV103_RS04140	COG0574	Belongs to the PEP-utilizing enzyme family
KV103_RS04145	COG2732	(Barnase) inhibitor
KV103_RS04150	COG2318	DinB family
KV103_RS04155	COG2814	Major facilitator Superfamily
KV103_RS04160	COG1846	Transcriptional regulator
KV103_RS04165	COG0392	lysyltransferase activity
KV103_RS04165	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KV103_RS04170	COG0384	phenazine biosynthesis protein PhzF
KV103_RS04175	COG0778	Nitroreductase
KV103_RS04190	COG1090	epimerase
KV103_RS04205	COG2814	Major facilitator Superfamily
KV103_RS04215	COG3591	Belongs to the peptidase S1B family
KV103_RS04230	COG3103	Sh3 type 3 domain protein
KV103_RS04235	COG5658	integral membrane protein
KV103_RS04240	COG0596	Alpha beta hydrolase
KV103_RS04245	COG0463	Glycosyl transferase, family 2
KV103_RS04250	COG4485	Bacterial membrane protein, YfhO
KV103_RS04255	COG1988	membrane-bound metal-dependent
KV103_RS04260	COG1194	a g-specific adenine glycosylase
KV103_RS04270	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS04290	COG1132	(ABC) transporter
KV103_RS04295	COG4129	membrane
KV103_RS04305	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KV103_RS04310	COG0735	belongs to the Fur family
KV103_RS04425	COG3340	Belongs to the peptidase S51 family
KV103_RS04435	COG0277	FAD linked oxidase domain protein
KV103_RS04445	COG0747	negative chemotaxis
KV103_RS04450	COG0601	transmembrane transport
KV103_RS04455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KV103_RS04460	COG0444	Belongs to the ABC transporter superfamily
KV103_RS04465	COG4608	Belongs to the ABC transporter superfamily
KV103_RS04470	COG0753	catalase activity
KV103_RS04480	COG1116	anion transmembrane transporter activity
KV103_RS04485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KV103_RS04490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KV103_RS04510	COG1476	TRANSCRIPTIONal
KV103_RS04520	COG3382	B3 4 domain protein
KV103_RS04525	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KV103_RS04535	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KV103_RS04540	COG0789	Transcriptional regulator
KV103_RS04545	COG1664	Polymer-forming cytoskeletal
KV103_RS04550	COG1664	Polymer-forming cytoskeletal
KV103_RS04555	COG2766	serine protein kinase
KV103_RS04565	COG1846	Transcriptional regulator
KV103_RS04570	COG1566	PFAM secretion protein HlyD family protein
KV103_RS04575	COG2814	Major facilitator Superfamily
KV103_RS04580	COG0655	NAD(P)H dehydrogenase (quinone) activity
KV103_RS04595	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KV103_RS04600	COG1278	Cold shock
KV103_RS04605	COG1464	Belongs to the NlpA lipoprotein family
KV103_RS04610	COG3706	GGDEF domain
KV103_RS04615	COG1823	symporter activity
KV103_RS04635	COG5577	PFAM Coat F domain
KV103_RS04640	COG4085	toxin activity
KV103_RS04640	COG0737	Belongs to the 5'-nucleotidase family
KV103_RS04640	COG1525	nuclease
KV103_RS04645	COG3764	Sortase (surface protein transpeptidase)
KV103_RS04650	COG0564	pseudouridine synthase activity
KV103_RS04660	COG0517	IMP dehydrogenase activity
KV103_RS04665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KV103_RS04670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KV103_RS04670	COG3153	acetyltransferase
KV103_RS04675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KV103_RS04680	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KV103_RS04685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KV103_RS04695	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KV103_RS04700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KV103_RS04705	COG2203	Gaf domain
KV103_RS04705	COG4585	Histidine kinase
KV103_RS04710	COG2197	response regulator
KV103_RS04715	COG0431	NADPH-dependent FMN reductase
KV103_RS04730	COG0791	NLP P60 protein
KV103_RS04730	COG1388	LysM domain
KV103_RS04735	COG1959	2 iron, 2 sulfur cluster binding
KV103_RS04745	COG2719	SpoVR family
KV103_RS04750	COG1785	Belongs to the alkaline phosphatase family
KV103_RS04755	COG1388	LysM domain
KV103_RS04755	COG0791	NLP P60 protein
KV103_RS04760	COG0583	DNA-binding transcription factor activity
KV103_RS04765	COG0372	Belongs to the citrate synthase family
KV103_RS04770	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS04775	COG0531	amino acid
KV103_RS04780	COG0733	neurotransmitter:sodium symporter activity
KV103_RS04795	COG1595	DNA-templated transcription, initiation
KV103_RS04800	COG0204	Acyl-transferase
KV103_RS04805	COG1253	flavin adenine dinucleotide binding
KV103_RS04810	COG0789	Transcriptional regulator
KV103_RS04815	COG0436	Aminotransferase
KV103_RS04820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KV103_RS04825	COG1253	flavin adenine dinucleotide binding
KV103_RS04830	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KV103_RS04835	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KV103_RS04840	COG0584	glycerophosphoryl diester phosphodiesterase
KV103_RS04850	COG0668	transmembrane transport
KV103_RS04855	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KV103_RS04860	COG0726	polysaccharide deacetylase
KV103_RS04865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KV103_RS04870	COG3226	Transcriptional regulator
KV103_RS04880	COG0589	response to stress
KV103_RS04885	COG1132	(ABC) transporter
KV103_RS04890	COG1132	(ABC) transporter
KV103_RS04895	COG0702	epimerase
KV103_RS04910	COG0189	ligase activity
KV103_RS04915	COG0189	ligase activity
KV103_RS04930	COG4335	DNA alkylation repair
KV103_RS04935	COG0561	phosphatase activity
KV103_RS04940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KV103_RS04950	COG0475	glutathione-regulated potassium exporter activity
KV103_RS04955	COG0490	domain, Protein
KV103_RS04965	COG1024	Enoyl-CoA hydratase
KV103_RS04975	COG4152	abc transporter atp-binding protein
KV103_RS04980	COG1668	transmembrane transport
KV103_RS04985	COG0420	3'-5' exonuclease activity
KV103_RS04990	COG4717	serine-type aminopeptidase activity
KV103_RS05005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KV103_RS05040	COG4980	gas vesicle protein
KV103_RS05055	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KV103_RS05060	COG0537	adenosine 5'-monophosphoramidase activity
KV103_RS05065	COG1131	(ABC) transporter
KV103_RS05070	COG4473	ABC transporter
KV103_RS05080	COG1473	amidohydrolase
KV103_RS05085	COG3069	C4-dicarboxylate transmembrane transporter activity
KV103_RS05090	COG2329	Antibiotic biosynthesis monooxygenase
KV103_RS05095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KV103_RS05105	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KV103_RS05110	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KV103_RS05115	COG1309	transcriptional regulator
KV103_RS05120	COG1511	domain protein
KV103_RS05125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KV103_RS05135	COG1363	Peptidase, m42
KV103_RS05140	COG1301	dicarboxylic acid transport
KV103_RS05150	COG1234	tRNA 3'-trailer cleavage
KV103_RS05155	COG0095	Lipoate-protein ligase
KV103_RS05160	COG0702	epimerase
KV103_RS05165	COG0318	PFAM AMP-dependent synthetase and ligase
KV103_RS05175	COG0501	Belongs to the peptidase M48B family
KV103_RS05180	COG1404	Belongs to the peptidase S8 family
KV103_RS05185	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KV103_RS05190	COG0406	alpha-ribazole phosphatase activity
KV103_RS05195	COG0183	Belongs to the thiolase family
KV103_RS05200	COG0318	PFAM AMP-dependent synthetase and ligase
KV103_RS05205	COG1268	BioY protein
KV103_RS05210	COG0840	transmembrane signaling receptor activity
KV103_RS05215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KV103_RS05215	COG0723	plastoquinol--plastocyanin reductase activity
KV103_RS05220	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS05230	COG4903	ComK protein
KV103_RS05240	COG5646	InterPro IPR014922
KV103_RS05260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KV103_RS05275	COG0398	Pfam SNARE associated Golgi protein
KV103_RS05280	COG0681	Belongs to the peptidase S26 family
KV103_RS05285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KV103_RS05290	COG1846	Transcriptional regulator
KV103_RS05295	COG3180	Ammonia monooxygenase
KV103_RS05300	COG2814	Major facilitator Superfamily
KV103_RS05310	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KV103_RS05315	COG2323	membrane
KV103_RS05330	COG0420	3'-5' exonuclease activity
KV103_RS05335	COG0419	ATPase involved in DNA repair
KV103_RS05340	COG1403	HNH endonuclease
KV103_RS05380	COG0179	Fumarylacetoacetate (FAA) hydrolase
KV103_RS05395	COG0367	asparagine synthase
KV103_RS05400	COG1562	ergosterol biosynthetic process
KV103_RS05405	COG0534	Mate efflux family protein
KV103_RS05410	COG1917	Cupin 2, conserved barrel domain protein
KV103_RS05410	COG2207	Transcriptional regulator
KV103_RS05420	COG2318	DinB family
KV103_RS05425	COG1279	arginine transmembrane transporter activity
KV103_RS05430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KV103_RS05435	COG1357	PFAM Pentapeptide repeats (8 copies)
KV103_RS05440	COG2153	protein acetylation
KV103_RS05445	COG0646	methionine synthase
KV103_RS05445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KV103_RS05455	COG2996	Protein conserved in bacteria
KV103_RS05460	COG1744	ABC transporter substrate-binding protein PnrA-like
KV103_RS05465	COG0840	transmembrane signaling receptor activity
KV103_RS05470	COG2124	cytochrome p450
KV103_RS05480	COG1307	EDD domain protein, DegV family
KV103_RS05485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KV103_RS05505	COG0561	phosphatase activity
KV103_RS05510	COG1073	alpha beta
KV103_RS05515	COG2151	metal-sulfur cluster biosynthetic enzyme
KV103_RS05525	COG0277	FAD linked oxidase domain protein
KV103_RS05530	COG2271	Major facilitator Superfamily
KV103_RS05540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KV103_RS05550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KV103_RS05555	COG0505	Belongs to the CarA family
KV103_RS05560	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KV103_RS05565	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KV103_RS05580	COG2267	carboxylic ester hydrolase activity
KV103_RS05590	COG1744	ABC transporter substrate-binding protein PnrA-like
KV103_RS05605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KV103_RS05610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KV103_RS05615	COG5504	Zn-dependent protease
KV103_RS05620	COG0444	Belongs to the ABC transporter superfamily
KV103_RS05625	COG4608	Belongs to the ABC transporter superfamily
KV103_RS05635	COG0601	transmembrane transport
KV103_RS05640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KV103_RS05650	COG0180	Tryptophanyl-tRNA synthetase
KV103_RS05655	COG4166	transmembrane transport
KV103_RS05660	COG0601	transmembrane transport
KV103_RS05665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KV103_RS05670	COG0444	Belongs to the ABC transporter superfamily
KV103_RS05675	COG4608	Belongs to the ABC transporter superfamily
KV103_RS05685	COG0456	acetyltransferase
KV103_RS05690	COG1393	Belongs to the ArsC family
KV103_RS05695	COG0861	Integral membrane protein TerC family
KV103_RS05705	COG4862	establishment of competence for transformation
KV103_RS05710	COG4469	Competence protein
KV103_RS05715	COG1164	Oligoendopeptidase f
KV103_RS05725	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KV103_RS05730	COG2346	COG2346, Truncated hemoglobins
KV103_RS05735	COG0741	lytic transglycosylase activity
KV103_RS05740	COG4116	CYTH
KV103_RS05750	COG2357	RelA SpoT domain protein
KV103_RS05755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KV103_RS05760	COG0564	pseudouridine synthase activity
KV103_RS05770	COG0475	glutathione-regulated potassium exporter activity
KV103_RS05770	COG0569	domain protein
KV103_RS05775	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KV103_RS05780	COG0352	thiamine-phosphate diphosphorylase activity
KV103_RS05785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KV103_RS05790	COG2104	thiamine diphosphate biosynthetic process
KV103_RS05800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KV103_RS05805	COG0351	phosphomethylpyrimidine kinase
KV103_RS05810	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KV103_RS05865	COG0210	DNA helicase
KV103_RS05885	COG1131	(ABC) transporter
KV103_RS05895	COG2153	protein acetylation
KV103_RS05905	COG2382	esterase
KV103_RS05910	COG0626	cystathionine gamma-synthase activity
KV103_RS05915	COG0626	cystathionine gamma-synthase activity
KV103_RS05945	COG5444	nuclease activity
KV103_RS05955	COG0346	lactoylglutathione lyase activity
KV103_RS05960	COG2367	Beta-lactamase
KV103_RS05965	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KV103_RS05970	COG0477	Major facilitator Superfamily
KV103_RS05975	COG1846	Transcriptional regulator
KV103_RS05985	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KV103_RS05990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KV103_RS05995	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KV103_RS06000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV103_RS06000	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV103_RS06005	COG1447	Phosphotransferase system cellobiose-specific component IIA
KV103_RS06015	COG1349	DNA-binding transcription factor activity
KV103_RS06035	COG1285	pathogenesis
KV103_RS06050	COG2205	protein histidine kinase activity
KV103_RS06060	COG3383	formate dehydrogenase (NAD+) activity
KV103_RS06065	COG2427	Protein of unknown function (DUF1641)
KV103_RS06070	COG2124	cytochrome p450
KV103_RS06075	COG1819	glycosyl
KV103_RS06085	COG1587	Uroporphyrinogen-III synthase
KV103_RS06090	COG0390	transport system, permease component
KV103_RS06095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KV103_RS06100	COG0697	spore germination
KV103_RS06105	COG4297	protein containing double-stranded beta helix domain
KV103_RS06115	COG1252	NADH dehydrogenase
KV103_RS06125	COG2211	Major facilitator Superfamily
KV103_RS06130	COG1609	Transcriptional regulator
KV103_RS06135	COG0246	Mannitol dehydrogenase
KV103_RS06140	COG2721	sulfolactate sulfo-lyase activity
KV103_RS06145	COG0745	RESPONSE REGULATOR receiver
KV103_RS06150	COG2205	protein histidine kinase activity
KV103_RS06150	COG2770	Histidine kinase
KV103_RS06170	COG4585	Histidine kinase
KV103_RS06175	COG2197	response regulator
KV103_RS06210	COG0730	response to heat
KV103_RS06215	COG2318	DinB family
KV103_RS06220	COG0457	Tetratricopeptide repeat
KV103_RS06230	COG1388	LysM domain
KV103_RS06230	COG3409	Peptidoglycan-binding domain 1 protein
KV103_RS06230	COG5632	N-Acetylmuramoyl-L-alanine amidase
KV103_RS06240	COG4195	phage-related replication protein
KV103_RS06245	COG2856	Zn peptidase
KV103_RS06250	COG1396	sequence-specific DNA binding
KV103_RS06255	COG1522	sequence-specific DNA binding
KV103_RS06260	COG1484	DNA-dependent DNA replication
KV103_RS06280	COG1595	DNA-templated transcription, initiation
KV103_RS06285	COG5484	DNA packaging
KV103_RS06285	COG3728	DNA packaging
KV103_RS06290	COG1783	phage Terminase large subunit
KV103_RS06295	COG5518	Phage portal protein
KV103_RS06300	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KV103_RS06305	COG4653	Phage capsid family
KV103_RS06355	COG5412	phage tail tape measure protein
KV103_RS06355	COG3953	SLT domain
KV103_RS06355	COG5412	phage tail tape measure protein
KV103_RS06355	COG3953	SLT domain
KV103_RS06355	COG3953	SLT domain
KV103_RS06355	COG5412	phage tail tape measure protein
KV103_RS06360	COG1652	LysM domain
KV103_RS06365	COG4193	domain, Protein
KV103_RS06375	COG3628	GPW Gp25 family protein
KV103_RS06380	COG3299	homolog of phage Mu protein gp47
KV103_RS06385	COG3778	Protein conserved in bacteria
KV103_RS06425	COG5632	N-Acetylmuramoyl-L-alanine amidase
KV103_RS06425	COG3409	Peptidoglycan-binding domain 1 protein
KV103_RS06440	COG0306	phosphate transporter
KV103_RS06445	COG1392	Phosphate transport regulator
KV103_RS06450	COG0531	amino acid
KV103_RS06455	COG0346	lactoylglutathione lyase activity
KV103_RS06460	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KV103_RS06465	COG0463	Glycosyl transferase, family 2
KV103_RS06475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KV103_RS06480	COG0477	Major facilitator Superfamily
KV103_RS06485	COG2362	D-Aminopeptidase
KV103_RS06490	COG0601	transmembrane transport
KV103_RS06495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KV103_RS06500	COG0444	Belongs to the ABC transporter superfamily
KV103_RS06505	COG4166	transmembrane transport
KV103_RS06510	COG1619	proteins homologs of microcin C7 resistance protein MccF
KV103_RS06515	COG4948	Mandelate Racemase Muconate Lactonizing
KV103_RS06520	COG0791	NLP P60 protein
KV103_RS06525	COG4608	Belongs to the ABC transporter superfamily
KV103_RS06530	COG2706	6-phosphogluconolactonase activity
KV103_RS06535	COG1834	amidinotransferase
KV103_RS06540	COG1607	acyl-coa hydrolase
KV103_RS06545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KV103_RS06550	COG2076	Multidrug Resistance protein
KV103_RS06555	COG2076	Multidrug Resistance protein
KV103_RS06560	COG0788	formyltetrahydrofolate deformylase activity
KV103_RS06565	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KV103_RS06575	COG1764	response to oxidative stress
KV103_RS06580	COG1846	Transcriptional regulator
KV103_RS06585	COG1764	response to oxidative stress
KV103_RS06600	COG0457	Tetratricopeptide repeat
KV103_RS06600	COG0463	Glycosyl transferase, family 2
KV103_RS06620	COG1404	Belongs to the peptidase S8 family
KV103_RS06625	COG1366	Belongs to the anti-sigma-factor antagonist family
KV103_RS06630	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KV103_RS06635	COG1122	ATPase activity
KV103_RS06640	COG4721	ABC-type cobalt transport system, permease component
KV103_RS06645	COG1388	LysM domain
KV103_RS06645	COG3858	chitin binding
KV103_RS06655	COG2239	Acts as a magnesium transporter
KV103_RS06660	COG0789	Transcriptional regulator
KV103_RS06675	COG1846	Transcriptional regulator
KV103_RS06680	COG0726	polysaccharide deacetylase
KV103_RS06685	COG1793	dna ligase
KV103_RS06685	COG3285	dna ligase
KV103_RS06690	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KV103_RS06695	COG0586	Pfam SNARE associated Golgi protein
KV103_RS06705	COG1191	sigma factor activity
KV103_RS06730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KV103_RS06735	COG2323	membrane
KV103_RS06745	COG3594	Acyltransferase
KV103_RS06750	COG5002	protein histidine kinase activity
KV103_RS06755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KV103_RS06770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KV103_RS06775	COG0436	Aminotransferase
KV103_RS06805	COG3852	Histidine kinase
KV103_RS06810	COG1846	Transcriptional regulator
KV103_RS06815	COG1360	Flagellar Motor Protein
KV103_RS06820	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KV103_RS06825	COG0542	response to heat
KV103_RS06830	COG3949	Membrane
KV103_RS06845	COG0720	synthase
KV103_RS06850	COG0602	queuosine metabolic process
KV103_RS06865	COG1733	regulation of RNA biosynthetic process
KV103_RS06870	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS06885	COG4873	Protein conserved in bacteria
KV103_RS06895	COG3773	Cell wall hydrolase
KV103_RS06900	COG2244	polysaccharide biosynthetic process
KV103_RS06905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KV103_RS06910	COG2217	Heavy metal translocating P-type atpase
KV103_RS06915	COG0006	proline dipeptidase activity
KV103_RS06920	COG1609	Transcriptional regulator
KV103_RS06925	COG3711	transcriptional antiterminator
KV103_RS06930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KV103_RS06930	COG1263	PTS System
KV103_RS06930	COG2190	(PTS) system
KV103_RS06935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KV103_RS06940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KV103_RS06950	COG1533	DNA photolyase activity
KV103_RS06955	COG0840	transmembrane signaling receptor activity
KV103_RS06960	COG2084	Dehydrogenase
KV103_RS06965	COG2340	Cysteine-rich secretory protein family
KV103_RS06970	COG0768	penicillin binding
KV103_RS06975	COG4191	Histidine kinase
KV103_RS06980	COG0436	Aminotransferase
KV103_RS06990	COG0784	Response regulator, receiver
KV103_RS06990	COG0835	chemotaxis
KV103_RS07000	COG2814	Major facilitator Superfamily
KV103_RS07005	COG1376	ErfK ybiS ycfS ynhG family protein
KV103_RS07010	COG1408	metallophosphoesterase
KV103_RS07015	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS07025	COG2200	EAL domain
KV103_RS07030	COG4703	Protein of unknown function (DUF1797)
KV103_RS07035	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KV103_RS07045	COG0517	IMP dehydrogenase activity
KV103_RS07050	COG0583	DNA-binding transcription factor activity
KV103_RS07055	COG0716	FMN binding
KV103_RS07065	COG0716	FMN binding
KV103_RS07085	COG0668	transmembrane transport
KV103_RS07090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KV103_RS07110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KV103_RS07115	COG0303	'Molybdopterin
KV103_RS07120	COG1763	Mo-molybdopterin cofactor biosynthetic process
KV103_RS07125	COG0314	molybdopterin synthase activity
KV103_RS07130	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KV103_RS07140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KV103_RS07145	COG1136	(ABC) transporter
KV103_RS07150	COG0577	efflux transmembrane transporter activity
KV103_RS07155	COG1349	DNA-binding transcription factor activity
KV103_RS07160	COG1105	Belongs to the carbohydrate kinase PfkB family
KV103_RS07165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KV103_RS07165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KV103_RS07165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KV103_RS07170	COG0681	Belongs to the peptidase S26 family
KV103_RS07180	COG0488	(ABC) transporter
KV103_RS07185	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KV103_RS07190	COG2309	aminopeptidase activity
KV103_RS07200	COG1077	Cell shape determining protein MreB Mrl
KV103_RS07205	COG2002	toxin-antitoxin pair type II binding
KV103_RS07210	COG3852	Histidine kinase
KV103_RS07215	COG2105	PFAM AIG2 family protein
KV103_RS07215	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KV103_RS07220	COG0569	domain protein
KV103_RS07230	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KV103_RS07240	COG0561	phosphatase activity
KV103_RS07245	COG0242	peptide deformylase activity
KV103_RS07255	COG0497	DNA recombination
KV103_RS07260	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KV103_RS07260	COG2070	2-Nitropropane dioxygenase
KV103_RS07265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS07265	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS07265	COG3321	synthase
KV103_RS07265	COG4221	oxidoreductase activity
KV103_RS07270	COG4221	oxidoreductase activity
KV103_RS07270	COG3321	synthase
KV103_RS07270	COG0300	oxidoreductase activity
KV103_RS07270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV103_RS07275	COG4221	oxidoreductase activity
KV103_RS07275	COG3321	synthase
KV103_RS07275	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS07275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS07280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV103_RS07280	COG0300	oxidoreductase activity
KV103_RS07280	COG3321	synthase
KV103_RS07280	COG4221	oxidoreductase activity
KV103_RS07285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV103_RS07285	COG0300	oxidoreductase activity
KV103_RS07285	COG3321	synthase
KV103_RS07285	COG4221	oxidoreductase activity
KV103_RS07290	COG4221	oxidoreductase activity
KV103_RS07290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV103_RS07290	COG0300	oxidoreductase activity
KV103_RS07290	COG3321	synthase
KV103_RS07295	COG3321	synthase
KV103_RS07295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS07295	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS07295	COG4221	oxidoreductase activity
KV103_RS07300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KV103_RS07305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KV103_RS07310	COG0022	dehydrogenase e1 component
KV103_RS07315	COG0508	dehydrogenase complex catalyzes the overall conversion of
KV103_RS07320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KV103_RS07325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KV103_RS07340	COG1982	Orn Lys Arg decarboxylase major
KV103_RS07360	COG0483	inositol monophosphate 1-phosphatase activity
KV103_RS07370	COG3227	Zinc metalloprotease (Elastase)
KV103_RS07375	COG1595	DNA-templated transcription, initiation
KV103_RS07395	COG1217	gtp-binding protein TYPA
KV103_RS07405	COG4896	Protein conserved in bacteria
KV103_RS07415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KV103_RS07420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KV103_RS07425	COG2066	Belongs to the glutaminase family
KV103_RS07435	COG0772	Belongs to the SEDS family
KV103_RS07440	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KV103_RS07455	COG2010	Cytochrome c
KV103_RS07455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KV103_RS07460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KV103_RS07465	COG1845	cytochrome c oxidase, subunit III
KV103_RS07470	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KV103_RS07475	COG3336	cytochrome c oxidase
KV103_RS07485	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KV103_RS07490	COG2340	Cysteine-rich secretory protein family
KV103_RS07505	COG3679	Belongs to the UPF0342 family
KV103_RS07515	COG0742	ribosomal rna small subunit methyltransferase
KV103_RS07525	COG3314	Sporulation integral membrane protein YlbJ
KV103_RS07530	COG1752	Esterase of the alpha-beta hydrolase superfamily
KV103_RS07535	COG3480	Lon protease (S16) C-terminal proteolytic domain
KV103_RS07545	COG1399	metal-binding, possibly nucleic acid-binding protein
KV103_RS07565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KV103_RS07585	COG4839	cell division protein FtsL
KV103_RS07590	COG0768	penicillin binding
KV103_RS07595	COG0768	penicillin binding
KV103_RS07615	COG0772	Belongs to the SEDS family
KV103_RS07630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KV103_RS07635	COG0849	cell division
KV103_RS07640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KV103_RS07645	COG4412	M6 family metalloprotease domain protein
KV103_RS07645	COG1404	Belongs to the peptidase S8 family
KV103_RS07655	COG1191	sigma factor activity
KV103_RS07660	COG1191	sigma factor activity
KV103_RS07665	COG1119	ATPase activity
KV103_RS07670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KV103_RS07675	COG1873	PFAM PRC-barrel domain
KV103_RS07680	COG1496	oxidoreductase activity
KV103_RS07685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KV103_RS07695	COG0762	integral membrane protein
KV103_RS07700	COG2302	S4 RNA-binding domain
KV103_RS07705	COG3599	regulation of cell shape
KV103_RS07710	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KV103_RS07715	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KV103_RS07725	COG0564	pseudouridine synthase activity
KV103_RS07735	COG2233	PERMEase
KV103_RS07745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KV103_RS07750	COG0505	Belongs to the CarA family
KV103_RS07755	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KV103_RS07770	COG0284	orotidine-5'-phosphate decarboxylase activity
KV103_RS07775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KV103_RS07785	COG0306	phosphate transporter
KV103_RS07800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KV103_RS07805	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KV103_RS07810	COG1648	precorrin-2 dehydrogenase activity
KV103_RS07820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KV103_RS07825	COG1561	YicC-like family, N-terminal region
KV103_RS07835	COG0194	GDP metabolic process
KV103_RS07845	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KV103_RS07850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KV103_RS07855	COG0242	peptide deformylase activity
KV103_RS07865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KV103_RS07865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KV103_RS07875	COG0631	protein serine/threonine phosphatase activity
KV103_RS07880	COG0515	serine threonine protein kinase
KV103_RS07880	COG2815	serine threonine protein kinase
KV103_RS07890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KV103_RS07895	COG1564	THIamine pyrophosphokinase
KV103_RS07910	COG1302	Protein conserved in bacteria
KV103_RS07915	COG1461	Dihydroxyacetone kinase
KV103_RS07920	COG1760	l-serine dehydratase
KV103_RS07925	COG1760	l-serine dehydratase
KV103_RS07930	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KV103_RS07945	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KV103_RS07950	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS07965	COG1196	nuclear chromosome segregation
KV103_RS07970	COG0552	protein localization to endoplasmic reticulum
KV103_RS07985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KV103_RS07995	COG1837	Belongs to the UPF0109 family
KV103_RS08020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KV103_RS08035	COG2257	FlhB HrpN YscU SpaS Family
KV103_RS08045	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KV103_RS08050	COG0758	DNA mediated transformation
KV103_RS08055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KV103_RS08065	COG4974	Belongs to the 'phage' integrase family
KV103_RS08085	COG1815	bacterial-type flagellum-dependent cell motility
KV103_RS08090	COG1558	bacterial-type flagellum-dependent cell motility
KV103_RS08095	COG1677	Flagellar hook-basal body complex protein FliE
KV103_RS08100	COG1766	The M ring may be actively involved in energy transduction
KV103_RS08105	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KV103_RS08110	COG1317	bacterial-type flagellum organization
KV103_RS08115	COG1157	protein secretion by the type III secretion system
KV103_RS08120	COG2882	bacterial-type flagellum organization
KV103_RS08125	COG3334	PFAM MgtE intracellular
KV103_RS08130	COG3144	bacterial-type flagellum assembly
KV103_RS08135	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KV103_RS08140	COG4786	Flagellar basal body rod
KV103_RS08145	COG1582	Flagellar protein (FlbD)
KV103_RS08150	COG1580	Controls the rotational direction of flagella during chemotaxis
KV103_RS08155	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KV103_RS08160	COG1776	CheC inhibitor of MCP methylation
KV103_RS08160	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KV103_RS08165	COG2201	protein-glutamate methylesterase activity
KV103_RS08170	COG3190	flagellar
KV103_RS08175	COG1338	Plays a role in the flagellum-specific transport system
KV103_RS08180	COG1987	bacterial-type flagellum assembly
KV103_RS08185	COG1684	flagellar biosynthetic protein fliR
KV103_RS08190	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KV103_RS08195	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KV103_RS08200	COG1419	protein localization to endoplasmic reticulum
KV103_RS08205	COG0455	bacterial-type flagellum organization
KV103_RS08210	COG2201	protein-glutamate methylesterase activity
KV103_RS08215	COG0643	Histidine kinase
KV103_RS08215	COG2198	Histidine kinase
KV103_RS08220	COG0835	chemotaxis
KV103_RS08225	COG1776	CheC inhibitor of MCP methylation
KV103_RS08235	COG1191	sigma factor activity
KV103_RS08265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KV103_RS08270	COG4589	Belongs to the CDS family
KV103_RS08280	COG0750	zinc metalloprotease
KV103_RS08300	COG0195	Participates in both transcription termination and antitermination
KV103_RS08305	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KV103_RS08310	COG1358	cellular component organization or biogenesis
KV103_RS08320	COG1550	Protein conserved in bacteria
KV103_RS08335	COG0196	riboflavin kinase activity
KV103_RS08350	COG0726	polysaccharide deacetylase
KV103_RS08355	COG0612	Peptidase, M16
KV103_RS08360	COG1873	PFAM PRC-barrel domain
KV103_RS08365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KV103_RS08370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KV103_RS08375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KV103_RS08380	COG0527	aspartate kinase activity
KV103_RS08390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KV103_RS08395	COG0740	serine-type endopeptidase activity
KV103_RS08405	COG1674	ftsk spoiiie
KV103_RS08405	COG4980	gas vesicle protein
KV103_RS08410	COG2188	Transcriptional regulator
KV103_RS08415	COG2814	Major facilitator Superfamily
KV103_RS08420	COG1846	Transcriptional regulator
KV103_RS08425	COG2409	Drug exporters of the RND superfamily
KV103_RS08425	COG1033	growth of symbiont in host cell
KV103_RS08430	COG0612	Peptidase, M16
KV103_RS08435	COG0612	Peptidase, M16
KV103_RS08440	COG0300	oxidoreductase activity
KV103_RS08455	COG1426	Protein conserved in bacteria
KV103_RS08460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KV103_RS08475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KV103_RS08485	COG1692	metallophosphoesterase
KV103_RS08490	COG2359	stage V sporulation protein S
KV103_RS08510	COG4550	Control of competence regulator ComK, YlbF/YmcA
KV103_RS08555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV103_RS08560	COG3425	synthase
KV103_RS08565	COG1024	Enoyl-CoA hydratase
KV103_RS08570	COG1024	Enoyl-CoA hydratase
KV103_RS08575	COG0300	oxidoreductase activity
KV103_RS08575	COG0318	PFAM AMP-dependent synthetase and ligase
KV103_RS08575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS08575	COG3321	synthase
KV103_RS08580	COG4221	oxidoreductase activity
KV103_RS08580	COG3321	synthase
KV103_RS08580	COG0300	oxidoreductase activity
KV103_RS08580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV103_RS08585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS08585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS08585	COG3321	synthase
KV103_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS08585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV103_RS08585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KV103_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS08585	COG3321	synthase
KV103_RS08585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV103_RS08585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KV103_RS08590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS08590	COG4221	oxidoreductase activity
KV103_RS08590	COG3321	synthase
KV103_RS08590	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS08595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KV103_RS08595	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KV103_RS08595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV103_RS08595	COG3321	synthase
KV103_RS08600	COG2124	cytochrome p450
KV103_RS08605	COG3209	COG3209 Rhs family protein
KV103_RS08610	COG3619	membrane
KV103_RS08620	COG1404	Belongs to the peptidase S8 family
KV103_RS08630	COG4195	phage-related replication protein
KV103_RS08635	COG1764	response to oxidative stress
KV103_RS08645	COG2076	Multidrug Resistance protein
KV103_RS08685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KV103_RS08690	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KV103_RS08695	COG4112	unkown
KV103_RS08700	COG0860	N-Acetylmuramoyl-L-alanine amidase
KV103_RS08705	COG0464	growth
KV103_RS08710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KV103_RS08715	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KV103_RS08720	COG0789	Transcriptional regulator
KV103_RS08725	COG0174	glutamine synthetase
KV103_RS08765	COG2211	Major facilitator Superfamily
KV103_RS08770	COG3507	Belongs to the glycosyl hydrolase 43 family
KV103_RS08785	COG1070	Carbohydrate kinase
KV103_RS08790	COG0574	Belongs to the PEP-utilizing enzyme family
KV103_RS08790	COG3848	Pyruvate phosphate dikinase
KV103_RS08810	COG2318	DinB family
KV103_RS08815	COG1064	alcohol dehydrogenase
KV103_RS08820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KV103_RS08820	COG4451	ribulose bisphosphate carboxylase, small
KV103_RS08860	COG3397	chitin binding
KV103_RS08880	COG5434	Belongs to the glycosyl hydrolase 28 family
KV103_RS08885	COG0756	dUTP diphosphatase activity
KV103_RS08890	COG4195	phage-related replication protein
KV103_RS08925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KV103_RS08935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KV103_RS08955	COG0785	Cytochrome C biogenesis protein
KV103_RS08960	COG2201	protein-glutamate methylesterase activity
KV103_RS08965	COG4846	Membrane protein involved in cytochrome C biogenesis
KV103_RS08975	COG0071	Belongs to the small heat shock protein (HSP20) family
KV103_RS08990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KV103_RS08995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KV103_RS09015	COG0824	Thioesterase
KV103_RS09025	COG4841	protein insertion into membrane
KV103_RS09035	COG1832	CoA-binding protein
KV103_RS09040	COG0187	DNA topoisomerase II activity
KV103_RS09045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KV103_RS09055	COG1115	amino acid carrier protein
KV103_RS09065	COG1063	alcohol dehydrogenase
KV103_RS09070	COG0800	Aldolase
KV103_RS09075	COG1312	Catalyzes the dehydration of D-mannonate
KV103_RS09080	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS09085	COG1609	Transcriptional regulator
KV103_RS09090	COG2271	Major facilitator Superfamily
KV103_RS09135	COG2205	protein histidine kinase activity
KV103_RS09140	COG0745	RESPONSE REGULATOR receiver
KV103_RS09150	COG3507	Belongs to the glycosyl hydrolase 43 family
KV103_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS09180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KV103_RS09185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KV103_RS09190	COG2610	gluconate transmembrane transporter activity
KV103_RS09195	COG2124	cytochrome p450
KV103_RS09215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KV103_RS09225	COG2246	polysaccharide biosynthetic process
KV103_RS09235	COG0586	Pfam SNARE associated Golgi protein
KV103_RS09240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KV103_RS09245	COG1024	Enoyl-CoA hydratase
KV103_RS09250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KV103_RS09255	COG0511	ligase activity, forming carbon-carbon bonds
KV103_RS09260	COG0439	Biotin carboxylase
KV103_RS09265	COG0318	PFAM AMP-dependent synthetase and ligase
KV103_RS09270	COG1960	acyl-CoA dehydrogenase activity
KV103_RS09275	COG1649	PFAM Uncharacterised BCR, COG1649
KV103_RS09285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS09285	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KV103_RS09290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS09295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS09300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS09305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS09310	COG2027	D-alanyl-D-alanine carboxypeptidase
KV103_RS09315	COG2017	converts alpha-aldose to the beta-anomer
KV103_RS09320	COG0534	Mate efflux family protein
KV103_RS09335	COG0582	viral genome integration into host DNA
KV103_RS09340	COG0166	Belongs to the GPI family
KV103_RS09345	COG0405	Gamma-glutamyltransferase
KV103_RS09350	COG2814	Major facilitator Superfamily
KV103_RS09355	COG0640	Transcriptional regulator
KV103_RS09360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KV103_RS09370	COG0604	alcohol dehydrogenase
KV103_RS09375	COG0493	'glutamate synthase
KV103_RS09380	COG0069	glutamate synthase activity
KV103_RS09380	COG0067	glutamate synthase
KV103_RS09380	COG0070	glutamate synthase
KV103_RS09385	COG0583	DNA-binding transcription factor activity
KV103_RS09390	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KV103_RS09405	COG0300	oxidoreductase activity
KV103_RS09410	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KV103_RS09420	COG2814	Major facilitator Superfamily
KV103_RS09425	COG1070	Carbohydrate kinase
KV103_RS09430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KV103_RS09435	COG0243	molybdopterin cofactor binding
KV103_RS09465	COG5444	nuclease activity
KV103_RS09470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KV103_RS09475	COG0662	Cupin 2, conserved barrel domain protein
KV103_RS09475	COG2207	Transcriptional regulator
KV103_RS09480	COG1309	transcriptional regulator
KV103_RS09485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KV103_RS09495	COG0640	Transcriptional regulator
KV103_RS09500	COG0741	lytic transglycosylase activity
KV103_RS09505	COG2322	membrane
KV103_RS09520	COG1619	proteins homologs of microcin C7 resistance protein MccF
KV103_RS09530	COG1388	LysM domain
KV103_RS09530	COG3584	3D domain protein
KV103_RS09535	COG0514	ATP-dependent DNA helicase (RecQ)
KV103_RS09545	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KV103_RS09550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KV103_RS09565	COG0071	Belongs to the small heat shock protein (HSP20) family
KV103_RS09595	COG1012	belongs to the aldehyde dehydrogenase family
KV103_RS09600	COG1657	PFAM Prenyltransferase squalene oxidase
KV103_RS09605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KV103_RS09610	COG0733	neurotransmitter:sodium symporter activity
KV103_RS09615	COG0385	Bile acid
KV103_RS09620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KV103_RS09625	COG0508	dehydrogenase complex catalyzes the overall conversion of
KV103_RS09635	COG4548	von Willebrand factor, type A
KV103_RS09640	COG0714	Associated with various cellular activities
KV103_RS09645	COG2032	superoxide dismutase activity
KV103_RS09650	COG0791	NLP P60 protein
KV103_RS09650	COG1388	LysM domain
KV103_RS09655	COG1819	glycosyl
KV103_RS09660	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KV103_RS09665	COG0534	Mate efflux family protein
KV103_RS09670	COG1366	Belongs to the anti-sigma-factor antagonist family
KV103_RS09675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KV103_RS09680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KV103_RS09690	COG2962	Rard protein
KV103_RS09705	COG1942	4-Oxalocrotonate Tautomerase
KV103_RS09715	COG1733	regulation of RNA biosynthetic process
KV103_RS09720	COG0778	Nitroreductase
KV103_RS09725	COG0400	carboxylic ester hydrolase activity
KV103_RS09730	COG0346	lactoylglutathione lyase activity
KV103_RS09740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KV103_RS09750	COG2723	6-phospho-beta-galactosidase activity
KV103_RS09755	COG2188	Transcriptional regulator
KV103_RS09760	COG0793	Belongs to the peptidase S41A family
KV103_RS09760	COG3409	Peptidoglycan-binding domain 1 protein
KV103_RS09765	COG2226	methyltransferase
KV103_RS09775	COG1876	peptidase activity
KV103_RS09795	COG0671	phosphoesterase, PA-phosphatase related
KV103_RS09825	COG1509	lysine 2,3-aminomutase activity
KV103_RS09830	COG0456	acetyltransferase
KV103_RS09835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KV103_RS09840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KV103_RS09845	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KV103_RS09850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KV103_RS09855	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KV103_RS09865	COG0456	acetyltransferase
KV103_RS09870	COG0463	Glycosyl transferase, family 2
KV103_RS09885	COG4641	Protein conserved in bacteria
KV103_RS09895	COG1086	Polysaccharide biosynthesis protein
KV103_RS09930	COG0457	Tetratricopeptide repeat
KV103_RS09940	COG3391	amine dehydrogenase activity
KV103_RS09960	COG5444	nuclease activity
KV103_RS09965	COG4282	regulation of fungal-type cell wall biogenesis
KV103_RS09970	COG1525	nuclease
KV103_RS09995	COG1846	Transcriptional regulator
KV103_RS10000	COG4698	Protein conserved in bacteria
KV103_RS10005	COG2755	lipolytic protein G-D-S-L family
KV103_RS10010	COG1999	signal sequence binding
KV103_RS10020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KV103_RS10025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KV103_RS10030	COG1272	protein, Hemolysin III
KV103_RS10035	COG0204	Acyl-transferase
KV103_RS10040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KV103_RS10055	COG2136	Putative SAM-dependent methyltransferase
KV103_RS10055	COG2521	methyltransferase
KV103_RS10080	COG0386	Belongs to the glutathione peroxidase family
KV103_RS10100	COG1278	Cold shock
KV103_RS10120	COG0328	RNA-DNA hybrid ribonuclease activity
KV103_RS10125	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KV103_RS10130	COG0328	RNA-DNA hybrid ribonuclease activity
KV103_RS10140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KV103_RS10155	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KV103_RS10165	COG1755	Isoprenylcysteine carboxyl methyltransferase
KV103_RS10170	COG3424	synthase
KV103_RS10190	COG1335	isochorismatase
KV103_RS10200	COG2233	PERMEase
KV103_RS10210	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KV103_RS10215	COG1199	ATP-dependent helicase activity
KV103_RS10230	COG0116	Belongs to the methyltransferase superfamily
KV103_RS10260	COG3359	exonuclease
KV103_RS10265	COG1205	dead DEAH box helicase
KV103_RS10265	COG1111	helicase
KV103_RS10270	COG2190	(PTS) system
KV103_RS10275	COG0071	Belongs to the small heat shock protein (HSP20) family
KV103_RS10315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KV103_RS10315	COG4499	WXG100 protein secretion system (Wss), protein YukC
KV103_RS10325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KV103_RS10330	COG3935	DnaD domain protein
KV103_RS10340	COG0436	Aminotransferase
KV103_RS10345	COG5353	protein conserved in bacteria
KV103_RS10355	COG1199	ATP-dependent helicase activity
KV103_RS10355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KV103_RS10385	COG0438	transferase activity, transferring glycosyl groups
KV103_RS10390	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KV103_RS10405	COG1694	Mazg nucleotide pyrophosphohydrolase
KV103_RS10410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KV103_RS10425	COG4347	Protein of unknown function (DUF1405)
KV103_RS10430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KV103_RS10430	COG2010	Cytochrome c
KV103_RS10435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KV103_RS10440	COG0723	plastoquinol--plastocyanin reductase activity
KV103_RS10455	COG0457	Tetratricopeptide repeat
KV103_RS10465	COG0287	Prephenate dehydrogenase
KV103_RS10500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KV103_RS10505	COG4401	Chorismate mutase type I
KV103_RS10520	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KV103_RS10525	COG0105	UTP biosynthetic process
KV103_RS10530	COG0142	geranyltranstransferase activity
KV103_RS10540	COG0142	geranyltranstransferase activity
KV103_RS10555	COG0776	regulation of translation
KV103_RS10560	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KV103_RS10600	COG0539	negative regulation of cytoplasmic translation
KV103_RS10615	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KV103_RS10620	COG2959	enzyme of heme biosynthesis
KV103_RS10625	COG3773	Cell wall hydrolase
KV103_RS10625	COG3409	Peptidoglycan-binding domain 1 protein
KV103_RS10630	COG2339	peptidase activity
KV103_RS10635	COG0492	ferredoxin-NADP+ reductase activity
KV103_RS10640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KV103_RS10645	COG4862	establishment of competence for transformation
KV103_RS10650	COG1408	metallophosphoesterase
KV103_RS10660	COG1388	LysM domain
KV103_RS10665	COG1266	CAAX protease self-immunity
KV103_RS10670	COG0514	ATP-dependent DNA helicase (RecQ)
KV103_RS10675	COG4955	Helix-turn-helix domain
KV103_RS10680	COG1141	Ferredoxin
KV103_RS10685	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KV103_RS10690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KV103_RS10700	COG1595	DNA-templated transcription, initiation
KV103_RS10705	COG5002	protein histidine kinase activity
KV103_RS10710	COG0745	RESPONSE REGULATOR receiver
KV103_RS10715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KV103_RS10720	COG1333	cytochrome c biogenesis protein
KV103_RS10725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KV103_RS10730	COG1187	pseudouridine synthase activity
KV103_RS10735	COG0700	Nucleoside recognition
KV103_RS10740	COG2715	membrane protein required for spore maturation
KV103_RS10745	COG1686	Belongs to the peptidase S11 family
KV103_RS10770	COG1547	Domain of unknown function (DUF309)
KV103_RS10775	COG0456	acetyltransferase
KV103_RS10790	COG0307	riboflavin synthase, alpha
KV103_RS10795	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KV103_RS10795	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KV103_RS10805	COG0681	Belongs to the peptidase S26 family
KV103_RS10815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KV103_RS10820	COG4086	secreted protein
KV103_RS10825	COG0019	diaminopimelate decarboxylase activity
KV103_RS10830	COG0697	spore germination
KV103_RS10845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KV103_RS10865	COG1191	sigma factor activity
KV103_RS10875	COG1366	Belongs to the anti-sigma-factor antagonist family
KV103_RS10880	COG1686	Belongs to the peptidase S11 family
KV103_RS10885	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KV103_RS10890	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KV103_RS10895	COG4974	Belongs to the 'phage' integrase family
KV103_RS10905	COG0735	belongs to the Fur family
KV103_RS10910	COG1300	Membrane
KV103_RS10925	COG0281	malic enzyme
KV103_RS10930	COG1757	Na H antiporter
KV103_RS10935	COG1027	Aspartate ammonia-lyase
KV103_RS10940	COG0252	asparaginase activity
KV103_RS10945	COG1396	sequence-specific DNA binding
KV103_RS10950	COG1379	DNA repair
KV103_RS10955	COG0494	nUDIX hydrolase
KV103_RS10965	COG0667	Aldo Keto reductase
KV103_RS10975	COG1073	alpha beta
KV103_RS10985	COG4918	Iron-sulphur cluster biosynthesis
KV103_RS10990	COG0456	acetyltransferase
KV103_RS10990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KV103_RS10995	COG2329	Antibiotic biosynthesis monooxygenase
KV103_RS11000	COG0456	acetyltransferase
KV103_RS11005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KV103_RS11020	COG0628	permease
KV103_RS11030	COG0346	lactoylglutathione lyase activity
KV103_RS11040	COG3048	D-serine ammonia-lyase activity
KV103_RS11045	COG0300	oxidoreductase activity
KV103_RS11050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KV103_RS11055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KV103_RS11060	COG1024	Enoyl-CoA hydratase
KV103_RS11065	COG3425	synthase
KV103_RS11070	COG2124	cytochrome p450
KV103_RS11075	COG3321	synthase
KV103_RS11075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV103_RS11075	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS11075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KV103_RS11075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS11080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV103_RS11080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KV103_RS11080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS11080	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS11080	COG3321	synthase
KV103_RS11085	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS11085	COG3321	synthase
KV103_RS11085	COG0318	PFAM AMP-dependent synthetase and ligase
KV103_RS11085	COG0300	oxidoreductase activity
KV103_RS11085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS11090	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS11090	COG0318	PFAM AMP-dependent synthetase and ligase
KV103_RS11090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS11090	COG0300	oxidoreductase activity
KV103_RS11090	COG3321	synthase
KV103_RS11095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KV103_RS11095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV103_RS11095	COG3321	synthase
KV103_RS11095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS11095	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS11100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS11100	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS11100	COG3321	synthase
KV103_RS11100	COG0300	oxidoreductase activity
KV103_RS11100	COG0318	PFAM AMP-dependent synthetase and ligase
KV103_RS11105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV103_RS11105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS11105	COG3321	synthase
KV103_RS11105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KV103_RS11110	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS11115	COG0318	PFAM AMP-dependent synthetase and ligase
KV103_RS11130	COG2070	2-Nitropropane dioxygenase
KV103_RS11130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KV103_RS11135	COG0250	Participates in transcription elongation, termination and antitermination
KV103_RS11155	COG0596	Alpha beta hydrolase
KV103_RS11170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KV103_RS11175	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KV103_RS11190	COG0706	membrane insertase activity
KV103_RS11195	COG2195	Cleaves the N-terminal amino acid of tripeptides
KV103_RS11200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KV103_RS11205	COG0346	lactoylglutathione lyase activity
KV103_RS11220	COG4129	membrane
KV103_RS11225	COG1126	abc transporter atp-binding protein
KV103_RS11230	COG0765	amino acid transport
KV103_RS11235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KV103_RS11245	COG1597	lipid kinase activity
KV103_RS11250	COG0508	dehydrogenase complex catalyzes the overall conversion of
KV103_RS11255	COG0022	dehydrogenase e1 component
KV103_RS11260	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KV103_RS11265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KV103_RS11270	COG3426	butyrate kinase activity
KV103_RS11275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KV103_RS11280	COG0280	phosphate acetyltransferase
KV103_RS11285	COG3829	transcription factor binding
KV103_RS11285	COG3290	protein histidine kinase activity
KV103_RS11295	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KV103_RS11300	COG2079	MmgE PrpD family protein
KV103_RS11305	COG0372	Belongs to the citrate synthase family
KV103_RS11310	COG1960	acyl-CoA dehydrogenase activity
KV103_RS11315	COG1250	3-hydroxyacyl-CoA dehydrogenase
KV103_RS11320	COG0183	Belongs to the thiolase family
KV103_RS11325	COG0584	glycerophosphoryl diester phosphodiesterase
KV103_RS11330	COG0860	N-Acetylmuramoyl-L-alanine amidase
KV103_RS11355	COG1902	pentaerythritol trinitrate reductase activity
KV103_RS11370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KV103_RS11375	COG0745	RESPONSE REGULATOR receiver
KV103_RS11380	COG0750	zinc metalloprotease
KV103_RS11385	COG0497	DNA recombination
KV103_RS11395	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KV103_RS11405	COG0142	geranyltranstransferase activity
KV103_RS11415	COG1570	exodeoxyribonuclease VII activity
KV103_RS11430	COG1302	Protein conserved in bacteria
KV103_RS11435	COG0439	Biotin carboxylase
KV103_RS11440	COG0511	ligase activity, forming carbon-carbon bonds
KV103_RS11480	COG3854	ATPases associated with a variety of cellular activities
KV103_RS11495	COG0006	proline dipeptidase activity
KV103_RS11505	COG3872	metal-dependent enzyme
KV103_RS11515	COG1752	Esterase of the alpha-beta hydrolase superfamily
KV103_RS11530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KV103_RS11550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KV103_RS11565	COG1396	sequence-specific DNA binding
KV103_RS11575	COG0681	Belongs to the peptidase S26 family
KV103_RS11600	COG4940	Competence protein ComGF
KV103_RS11610	COG4970	Tfp pilus assembly protein FimT
KV103_RS11615	COG4537	Required for transformation and DNA binding
KV103_RS11620	COG1459	type II secretion system
KV103_RS11625	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KV103_RS11630	COG0598	Magnesium transport protein CorA
KV103_RS11635	COG1253	flavin adenine dinucleotide binding
KV103_RS11640	COG1366	Belongs to the anti-sigma-factor antagonist family
KV103_RS11650	COG1393	Belongs to the ArsC family
KV103_RS11660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KV103_RS11670	COG0011	TIGRFAM Protein of
KV103_RS11680	COG2866	Carboxypeptidase
KV103_RS11685	COG1940	carbohydrate kinase activity
KV103_RS11690	COG4483	Protein conserved in bacteria
KV103_RS11695	COG1757	Na H antiporter
KV103_RS11705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KV103_RS11720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KV103_RS11725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KV103_RS11730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KV103_RS11735	COG0581	inorganic phosphate transmembrane transporter activity
KV103_RS11740	COG0573	inorganic phosphate transmembrane transporter activity
KV103_RS11745	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KV103_RS11750	COG0768	penicillin binding
KV103_RS11755	COG0477	Major facilitator Superfamily
KV103_RS11760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KV103_RS11765	COG2839	Protein conserved in bacteria
KV103_RS11770	COG5521	maltodextrose utilization protein MalA
KV103_RS11775	COG1388	LysM domain
KV103_RS11785	COG4709	membrane
KV103_RS11790	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KV103_RS11795	COG0735	belongs to the Fur family
KV103_RS11800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KV103_RS11815	COG0513	Belongs to the DEAD box helicase family
KV103_RS11830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KV103_RS11835	COG2384	SAM-dependent methyltransferase
KV103_RS11840	COG2010	Cytochrome c
KV103_RS11845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KV103_RS11850	COG0358	DNA primase activity
KV103_RS11865	COG0517	IMP dehydrogenase activity
KV103_RS11870	COG0751	glycine-tRNA ligase activity
KV103_RS11890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KV103_RS11895	COG0295	cytidine deaminase activity
KV103_RS11900	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KV103_RS11910	COG1480	7TM receptor with intracellular HD hydrolase
KV103_RS11915	COG1702	phosphate starvation-inducible protein PhoH
KV103_RS11920	COG0561	phosphatase activity
KV103_RS11935	COG4864	UPF0365 protein
KV103_RS11940	COG1030	water channel activity
KV103_RS11945	COG1610	YqeY-like protein
KV103_RS11955	COG1283	sodium-dependent phosphate transmembrane transporter activity
KV103_RS11960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KV103_RS11965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KV103_RS11995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KV103_RS12010	COG0860	N-Acetylmuramoyl-L-alanine amidase
KV103_RS12040	COG0658	competence protein
KV103_RS12040	COG2333	competence protein COMEC
KV103_RS12045	COG2131	deaminase
KV103_RS12050	COG1555	photosystem II stabilization
KV103_RS12050	COG1596	polysaccharide export
KV103_RS12055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KV103_RS12060	COG2226	methyltransferase
KV103_RS12065	COG0799	negative regulation of ribosome biogenesis
KV103_RS12070	COG1713	HD superfamily hydrolase involved in NAD metabolism
KV103_RS12080	COG1534	Rna-binding protein
KV103_RS12085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KV103_RS12090	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KV103_RS12095	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KV103_RS12105	COG2755	lipolytic protein G-D-S-L family
KV103_RS12115	COG0398	Pfam SNARE associated Golgi protein
KV103_RS12140	COG1794	racemase activity, acting on amino acids and derivatives
KV103_RS12160	COG0656	L-ascorbic acid biosynthetic process
KV103_RS12190	COG3677	Transposase
KV103_RS12230	COG5002	protein histidine kinase activity
KV103_RS12230	COG0642	Histidine kinase
KV103_RS12235	COG0745	RESPONSE REGULATOR receiver
KV103_RS12240	COG2311	Membrane
KV103_RS12250	COG0454	-acetyltransferase
KV103_RS12255	COG0563	adenylate kinase activity
KV103_RS12260	COG2814	Major facilitator Superfamily
KV103_RS12270	COG0456	acetyltransferase
KV103_RS12275	COG2318	DinB family
KV103_RS12285	COG0561	phosphatase activity
KV103_RS12290	COG0561	phosphatase activity
KV103_RS12300	COG1482	cell wall glycoprotein biosynthetic process
KV103_RS12305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KV103_RS12305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KV103_RS12305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KV103_RS12310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KV103_RS12310	COG3711	transcriptional antiterminator
KV103_RS12320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KV103_RS12325	COG0583	DNA-binding transcription factor activity
KV103_RS12330	COG2814	Major facilitator Superfamily
KV103_RS12335	COG2124	cytochrome p450
KV103_RS12335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KV103_RS12340	COG1309	transcriptional regulator
KV103_RS12345	COG2226	methyltransferase
KV103_RS12360	COG2116	formate transmembrane transporter activity
KV103_RS12365	COG5609	conserved protein (DUF2294)
KV103_RS12370	COG3383	formate dehydrogenase (NAD+) activity
KV103_RS12375	COG2427	Protein of unknown function (DUF1641)
KV103_RS12385	COG0626	cystathionine gamma-synthase activity
KV103_RS12390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KV103_RS12415	COG0768	penicillin binding
KV103_RS12430	COG0826	peptidase U32
KV103_RS12435	COG0826	peptidase U32
KV103_RS12440	COG4122	O-methyltransferase activity
KV103_RS12445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KV103_RS12470	COG0628	permease
KV103_RS12475	COG1126	abc transporter atp-binding protein
KV103_RS12480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KV103_RS12485	COG0765	amino acid transport
KV103_RS12490	COG0765	amino acid transport
KV103_RS12505	COG3881	PFAM PRC-barrel domain
KV103_RS12510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KV103_RS12515	COG0457	Tetratricopeptide repeat
KV103_RS12525	COG1104	cysteine desulfurase activity
KV103_RS12530	COG1959	2 iron, 2 sulfur cluster binding
KV103_RS12535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KV103_RS12540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KV103_RS12565	COG3103	Sh3 type 3 domain protein
KV103_RS12565	COG0860	N-Acetylmuramoyl-L-alanine amidase
KV103_RS12565	COG4991	sh3 domain protein
KV103_RS12575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KV103_RS12585	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KV103_RS12585	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KV103_RS12590	COG5416	Lipopolysaccharide assembly protein A domain
KV103_RS12595	COG0490	domain, Protein
KV103_RS12600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KV103_RS12600	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KV103_RS12610	COG2244	polysaccharide biosynthetic process
KV103_RS12615	COG2323	membrane
KV103_RS12625	COG1862	Preprotein translocase
KV103_RS12665	COG1388	LysM domain
KV103_RS12675	COG0157	Belongs to the NadC ModD family
KV103_RS12680	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KV103_RS12685	COG1104	cysteine desulfurase activity
KV103_RS12690	COG1827	regulation of RNA biosynthetic process
KV103_RS12695	COG0077	Prephenate dehydratase
KV103_RS12710	COG3290	protein histidine kinase activity
KV103_RS12715	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KV103_RS12720	COG2868	ribosomal protein
KV103_RS12730	COG1994	Peptidase M50
KV103_RS12735	COG0739	heme binding
KV103_RS12740	COG2894	cell division
KV103_RS12745	COG0850	regulation of cytokinetic process
KV103_RS12750	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KV103_RS12760	COG1077	Cell shape determining protein MreB Mrl
KV103_RS12780	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KV103_RS12785	COG0285	dihydrofolate synthase activity
KV103_RS12790	COG0525	valine-tRNA ligase activity
KV103_RS12800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KV103_RS12805	COG1388	LysM domain
KV103_RS12815	COG0113	porphobilinogen synthase activity
KV103_RS12820	COG1587	Uroporphyrinogen-III synthase
KV103_RS12830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KV103_RS12850	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KV103_RS12855	COG0470	DNA polymerase III
KV103_RS12855	COG1067	ATP-dependent peptidase activity
KV103_RS12870	COG1477	protein flavinylation
KV103_RS12870	COG0457	Tetratricopeptide repeat
KV103_RS12885	COG0473	3-isopropylmalate dehydrogenase activity
KV103_RS12900	COG0440	acetolactate synthase activity
KV103_RS12905	COG0028	Belongs to the TPP enzyme family
KV103_RS12930	COG0622	Phosphoesterase
KV103_RS12935	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KV103_RS12945	COG5401	PFAM Sporulation and spore germination
KV103_RS12955	COG1846	Transcriptional regulator
KV103_RS12960	COG2197	response regulator
KV103_RS12965	COG0824	Thioesterase
KV103_RS12970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KV103_RS12975	COG1053	succinate dehydrogenase
KV103_RS12980	COG2009	succinate dehydrogenase
KV103_RS12985	COG1719	4-vinyl reductase, 4VR
KV103_RS12990	COG0527	aspartate kinase activity
KV103_RS13000	COG3118	belongs to the thioredoxin family
KV103_RS13005	COG3534	alpha-L-arabinofuranosidase
KV103_RS13010	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KV103_RS13015	COG2086	electron transfer activity
KV103_RS13020	COG1024	Enoyl-CoA hydratase
KV103_RS13025	COG1309	transcriptional regulator
KV103_RS13030	COG0318	PFAM AMP-dependent synthetase and ligase
KV103_RS13040	COG3766	membrane
KV103_RS13050	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KV103_RS13050	COG1796	DNA polymerase
KV103_RS13055	COG1286	toxin biosynthetic process
KV103_RS13070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KV103_RS13070	COG0072	phenylalanine-tRNA ligase activity
KV103_RS13075	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KV103_RS13080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KV103_RS13090	COG3835	regulator
KV103_RS13095	COG0277	FAD linked oxidase domain protein
KV103_RS13100	COG0247	lactate metabolic process
KV103_RS13105	COG1966	Carbon starvation protein
KV103_RS13110	COG3534	alpha-L-arabinofuranosidase
KV103_RS13115	COG0395	ABC-type sugar transport system, permease component
KV103_RS13120	COG1175	transmembrane transport
KV103_RS13125	COG1653	transport
KV103_RS13135	COG0647	UMP catabolic process
KV103_RS13140	COG0235	Class ii aldolase
KV103_RS13145	COG1069	ribulokinase activity
KV103_RS13150	COG2160	L-arabinose isomerase activity
KV103_RS13155	COG3507	Belongs to the glycosyl hydrolase 43 family
KV103_RS13160	COG1363	Peptidase, m42
KV103_RS13170	COG3326	Membrane
KV103_RS13185	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KV103_RS13190	COG1346	cytolysis
KV103_RS13195	COG1380	Effector of murein hydrolase LrgA
KV103_RS13200	COG3279	Response regulator of the LytR AlgR family
KV103_RS13205	COG3275	phosphorelay sensor kinase activity
KV103_RS13210	COG1011	Hydrolase
KV103_RS13225	COG0398	Pfam SNARE associated Golgi protein
KV103_RS13230	COG1484	DNA-dependent DNA replication
KV103_RS13235	COG3611	Membrane attachment protein
KV103_RS13250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KV103_RS13255	COG1733	regulation of RNA biosynthetic process
KV103_RS13260	COG2814	Major facilitator Superfamily
KV103_RS13265	COG0656	L-ascorbic acid biosynthetic process
KV103_RS13270	COG0237	dephospho-CoA kinase activity
KV103_RS13275	COG1971	Probably functions as a manganese efflux pump
KV103_RS13280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KV103_RS13285	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KV103_RS13285	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KV103_RS13290	COG5002	protein histidine kinase activity
KV103_RS13295	COG0745	RESPONSE REGULATOR receiver
KV103_RS13305	COG0538	isocitrate dehydrogenase activity
KV103_RS13310	COG0372	Belongs to the citrate synthase family
KV103_RS13340	COG0628	permease
KV103_RS13345	COG3030	protein affecting phage T7 exclusion by the F plasmid
KV103_RS13350	COG0469	pyruvate kinase activity
KV103_RS13370	COG0281	malic enzyme
KV103_RS13375	COG0587	DNA-directed DNA polymerase activity
KV103_RS13395	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KV103_RS13405	COG4109	DRTGG domain
KV103_RS13415	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS13430	COG0521	Mo-molybdopterin cofactor biosynthetic process
KV103_RS13440	COG0827	DNA restriction-modification system
KV103_RS13445	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KV103_RS13450	COG3874	Sporulation protein YtfJ
KV103_RS13460	COG1714	RDD family
KV103_RS13465	COG0616	signal peptide processing
KV103_RS13470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KV103_RS13475	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KV103_RS13480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KV103_RS13495	COG1104	cysteine desulfurase activity
KV103_RS13500	COG1114	Component of the transport system for branched-chain amino acids
KV103_RS13510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KV103_RS13515	COG1309	transcriptional regulator
KV103_RS13520	COG1956	GAF domain-containing protein
KV103_RS13525	COG2199	diguanylate cyclase activity
KV103_RS13525	COG2203	Gaf domain
KV103_RS13535	COG1012	belongs to the aldehyde dehydrogenase family
KV103_RS13540	COG4282	regulation of fungal-type cell wall biogenesis
KV103_RS13585	COG1017	nitric oxide dioxygenase activity
KV103_RS13585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KV103_RS13600	COG0693	protein deglycase activity
KV103_RS13615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KV103_RS13620	COG1378	Sugar-specific transcriptional regulator TrmB
KV103_RS13640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KV103_RS13645	COG0454	-acetyltransferase
KV103_RS13650	COG0517	IMP dehydrogenase activity
KV103_RS13655	COG0123	including yeast histone deacetylase and acetoin utilization protein
KV103_RS13660	COG1360	Flagellar Motor Protein
KV103_RS13665	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KV103_RS13670	COG1609	Transcriptional regulator
KV103_RS13675	COG1605	Chorismate mutase
KV103_RS13675	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KV103_RS13680	COG3118	belongs to the thioredoxin family
KV103_RS13685	COG4980	gas vesicle protein
KV103_RS13690	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KV103_RS13700	COG1674	ftsk spoiiie
KV103_RS13705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KV103_RS13715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KV103_RS13725	COG1363	Peptidase, m42
KV103_RS13730	COG5584	Small secreted protein
KV103_RS13735	COG0281	malic enzyme
KV103_RS13740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KV103_RS13755	COG0510	thiamine kinase activity
KV103_RS13760	COG1597	lipid kinase activity
KV103_RS13770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KV103_RS13775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KV103_RS13780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KV103_RS13785	COG2252	PERMEase
KV103_RS13790	COG4473	ABC transporter
KV103_RS13795	COG1131	(ABC) transporter
KV103_RS13800	COG1349	DNA-binding transcription factor activity
KV103_RS13805	COG1187	pseudouridine synthase activity
KV103_RS13810	COG2244	polysaccharide biosynthetic process
KV103_RS13815	COG2081	HI0933 family
KV103_RS13820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KV103_RS13830	COG1609	Transcriptional regulator
KV103_RS13835	COG1653	transport
KV103_RS13840	COG1175	transmembrane transport
KV103_RS13845	COG0395	ABC-type sugar transport system, permease component
KV103_RS13850	COG1486	melibiose metabolic process
KV103_RS13860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KV103_RS13875	COG2202	Pas domain
KV103_RS13875	COG1366	Belongs to the anti-sigma-factor antagonist family
KV103_RS13880	COG2814	Major facilitator Superfamily
KV103_RS13885	COG5522	Integral membrane protein (intg_mem_TP0381)
KV103_RS13890	COG0577	efflux transmembrane transporter activity
KV103_RS13895	COG1136	(ABC) transporter
KV103_RS13900	COG2205	protein histidine kinase activity
KV103_RS13905	COG0745	RESPONSE REGULATOR receiver
KV103_RS13910	COG0577	efflux transmembrane transporter activity
KV103_RS13915	COG1136	(ABC) transporter
KV103_RS13935	COG1131	(ABC) transporter
KV103_RS13940	COG1725	Transcriptional regulator
KV103_RS13950	COG1242	4 iron, 4 sulfur cluster binding
KV103_RS13955	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KV103_RS13965	COG0584	glycerophosphoryl diester phosphodiesterase
KV103_RS13975	COG2267	carboxylic ester hydrolase activity
KV103_RS13980	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KV103_RS13985	COG1113	amino acid transport
KV103_RS13990	COG0367	asparagine synthase
KV103_RS14010	COG1506	peptidase
KV103_RS14015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KV103_RS14020	COG1116	anion transmembrane transporter activity
KV103_RS14025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KV103_RS14030	COG0494	nUDIX hydrolase
KV103_RS14035	COG4824	toxin secretion phage lysis holin
KV103_RS14040	COG0783	Belongs to the Dps family
KV103_RS14065	COG0288	reversible hydration of carbon dioxide
KV103_RS14075	COG1271	oxidase subunit
KV103_RS14080	COG1294	oxidase, subunit
KV103_RS14095	COG4948	Mandelate Racemase Muconate Lactonizing
KV103_RS14105	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KV103_RS14110	COG0596	Alpha beta hydrolase
KV103_RS14120	COG1169	isochorismate synthase
KV103_RS14125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KV103_RS14130	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KV103_RS14255	COG3859	Proton-coupled thiamine transporter YuaJ
KV103_RS14260	COG2268	Band 7 protein
KV103_RS14265	COG1585	Membrane protein implicated in regulation of membrane protease activity
KV103_RS14270	COG2318	DinB family
KV103_RS14280	COG1454	alcohol dehydrogenase
KV103_RS14285	COG1012	belongs to the aldehyde dehydrogenase family
KV103_RS14290	COG1510	regulation of RNA biosynthetic process
KV103_RS14300	COG0569	domain protein
KV103_RS14305	COG1705	Flagellar rod assembly protein muramidase FlgJ
KV103_RS14310	COG1017	nitric oxide dioxygenase activity
KV103_RS14310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KV103_RS14335	COG0628	permease
KV103_RS14340	COG0673	inositol 2-dehydrogenase activity
KV103_RS14345	COG0693	protein deglycase activity
KV103_RS14350	COG0840	transmembrane signaling receptor activity
KV103_RS14355	COG0840	transmembrane signaling receptor activity
KV103_RS14360	COG0840	transmembrane signaling receptor activity
KV103_RS14365	COG0840	transmembrane signaling receptor activity
KV103_RS14380	COG2070	2-Nitropropane dioxygenase
KV103_RS14385	COG0432	Pfam Uncharacterised protein family UPF0047
KV103_RS14390	COG0366	Alpha amylase catalytic
KV103_RS14395	COG1253	flavin adenine dinucleotide binding
KV103_RS14400	COG2738	Putative neutral zinc metallopeptidase
KV103_RS14415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KV103_RS14440	COG1335	isochorismatase
KV103_RS14445	COG1979	alcohol dehydrogenase
KV103_RS14450	COG1979	alcohol dehydrogenase
KV103_RS14455	COG2155	Conserved Protein
KV103_RS14460	COG1098	S1 RNA binding domain
KV103_RS14465	COG0436	Aminotransferase
KV103_RS14470	COG1522	sequence-specific DNA binding
KV103_RS14475	COG2267	carboxylic ester hydrolase activity
KV103_RS14485	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KV103_RS14490	COG2205	protein histidine kinase activity
KV103_RS14500	COG5018	Exonuclease
KV103_RS14505	COG2814	Major facilitator Superfamily
KV103_RS14510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KV103_RS14515	COG3011	Protein conserved in bacteria
KV103_RS14525	COG3290	protein histidine kinase activity
KV103_RS14530	COG4565	transcriptional regulatory protein
KV103_RS14535	COG1744	ABC transporter substrate-binding protein PnrA-like
KV103_RS14540	COG3845	ABC transporter
KV103_RS14545	COG4603	Belongs to the binding-protein-dependent transport system permease family
KV103_RS14550	COG1079	Belongs to the binding-protein-dependent transport system permease family
KV103_RS14560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KV103_RS14560	COG2111	Na H antiporter
KV103_RS14565	COG2111	Na H antiporter
KV103_RS14570	COG1006	Multisubunit Na H antiporter MnhC subunit
KV103_RS14575	COG0651	ATP synthesis coupled electron transport
KV103_RS14580	COG1863	multisubunit Na H antiporter MnhE subunit
KV103_RS14585	COG2212	antiporter activity
KV103_RS14590	COG1320	monovalent cation:proton antiporter activity
KV103_RS14595	COG2050	protein possibly involved in aromatic compounds catabolism
KV103_RS14600	COG2197	response regulator
KV103_RS14605	COG4585	Histidine kinase
KV103_RS14635	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KV103_RS14640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KV103_RS14645	COG1335	isochorismatase
KV103_RS14650	COG5506	Protein of unknown function (DUF1694)
KV103_RS14665	COG0628	permease
KV103_RS14675	COG1418	mRNA catabolic process
KV103_RS14680	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS14690	COG1511	domain protein
KV103_RS14695	COG0433	COG0433 Predicted ATPase
KV103_RS14695	COG1674	ftsk spoiiie
KV103_RS14700	COG4499	WXG100 protein secretion system (Wss), protein YukC
KV103_RS14705	COG5417	Belongs to the EsaB family
KV103_RS14710	COG4842	Belongs to the WXG100 family
KV103_RS14715	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KV103_RS14715	COG2508	Transcriptional regulator
KV103_RS14720	COG0686	Belongs to the AlaDH PNT family
KV103_RS14725	COG5634	Uncharacterized conserved protein (DUF2278)
KV103_RS14730	COG3251	PFAM MbtH domain protein
KV103_RS14735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS14740	COG3433	isochorismatase activity
KV103_RS14740	COG1535	isochorismatase
KV103_RS14745	COG1021	2,3-dihydroxybenzoate-AMP ligase
KV103_RS14750	COG1169	isochorismate synthase
KV103_RS14755	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS14760	COG2819	hydrolase of the alpha beta superfamily
KV103_RS14765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KV103_RS14770	COG1268	BioY protein
KV103_RS14775	COG2056	Na+-H+ antiporter family
KV103_RS14785	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KV103_RS14790	COG3584	3D domain protein
KV103_RS14805	COG1252	NADH dehydrogenase
KV103_RS14835	COG1131	(ABC) transporter
KV103_RS14855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KV103_RS14860	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KV103_RS14865	COG0316	Belongs to the HesB IscA family
KV103_RS14875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KV103_RS14885	COG1252	NADH dehydrogenase
KV103_RS14890	COG4837	Protein of unknown function (DUF1462)
KV103_RS14895	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KV103_RS14900	COG1506	peptidase
KV103_RS14900	COG0823	Involved in the tonB-independent uptake of proteins
KV103_RS14900	COG4946	Tricorn protease homolog
KV103_RS14910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KV103_RS14915	COG0460	homoserine dehydrogenase
KV103_RS14920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KV103_RS14925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KV103_RS14930	COG0647	UMP catabolic process
KV103_RS14935	COG2445	Protein of unknown function DUF86
KV103_RS14940	COG4470	Protein conserved in bacteria
KV103_RS14950	COG0739	heme binding
KV103_RS14960	COG0737	Belongs to the 5'-nucleotidase family
KV103_RS14965	COG0730	response to heat
KV103_RS14970	COG1801	Protein of unknown function DUF72
KV103_RS14985	COG2508	Transcriptional regulator
KV103_RS15005	COG2814	Major facilitator Superfamily
KV103_RS15010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KV103_RS15015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KV103_RS15020	COG2356	endonuclease I
KV103_RS15025	COG3842	ATPase activity
KV103_RS15030	COG2188	Transcriptional regulator
KV103_RS15035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KV103_RS15040	COG0395	ABC-type sugar transport system, permease component
KV103_RS15045	COG1175	transmembrane transport
KV103_RS15050	COG1653	transport
KV103_RS15055	COG2222	sugar isomerase
KV103_RS15060	COG0789	Transcriptional regulator
KV103_RS15085	COG0322	excinuclease ABC activity
KV103_RS15090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KV103_RS15110	COG3409	Peptidoglycan-binding domain 1 protein
KV103_RS15115	COG0719	Fe-S assembly protein
KV103_RS15120	COG0822	iron-sulfur transferase activity
KV103_RS15125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KV103_RS15130	COG0719	Fe-S assembly protein
KV103_RS15135	COG0396	ATPase activity
KV103_RS15145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KV103_RS15150	COG1464	Belongs to the NlpA lipoprotein family
KV103_RS15155	COG2011	ABC-type metal ion transport system permease component
KV103_RS15160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KV103_RS15170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KV103_RS15175	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KV103_RS15190	COG1393	Belongs to the ArsC family
KV103_RS15195	COG1960	acyl-CoA dehydrogenase activity
KV103_RS15200	COG0183	Belongs to the thiolase family
KV103_RS15205	COG1024	Enoyl-CoA hydratase
KV103_RS15205	COG1250	3-hydroxyacyl-CoA dehydrogenase
KV103_RS15225	COG5577	PFAM Coat F domain
KV103_RS15230	COG1846	Transcriptional regulator
KV103_RS15235	COG0477	Major facilitator Superfamily
KV103_RS15240	COG1942	4-Oxalocrotonate Tautomerase
KV103_RS15245	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS15250	COG0583	DNA-binding transcription factor activity
KV103_RS15260	COG0583	DNA-binding transcription factor activity
KV103_RS15280	COG1120	ATPase activity
KV103_RS15295	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS15300	COG0783	Belongs to the Dps family
KV103_RS15305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KV103_RS15310	COG0745	RESPONSE REGULATOR receiver
KV103_RS15315	COG2205	protein histidine kinase activity
KV103_RS15315	COG2770	Histidine kinase
KV103_RS15325	COG1309	transcriptional regulator
KV103_RS15330	COG0114	fumarate hydratase activity
KV103_RS15340	COG0697	spore germination
KV103_RS15345	COG0814	amino acid
KV103_RS15355	COG2197	response regulator
KV103_RS15360	COG4585	Histidine kinase
KV103_RS15365	COG4758	membrane
KV103_RS15370	COG3595	metallopeptidase activity
KV103_RS15375	COG1842	Phage shock protein A
KV103_RS15380	COG4758	membrane
KV103_RS15385	COG2814	Major facilitator Superfamily
KV103_RS15390	COG2096	Adenosyltransferase
KV103_RS15395	COG1120	ATPase activity
KV103_RS15400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KV103_RS15405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KV103_RS15410	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS15415	COG3386	PFAM SMP-30 Gluconolaconase
KV103_RS15420	COG2205	protein histidine kinase activity
KV103_RS15425	COG0745	RESPONSE REGULATOR receiver
KV103_RS15435	COG1191	sigma factor activity
KV103_RS15445	COG2140	Oxalate decarboxylase
KV103_RS15455	COG1120	ATPase activity
KV103_RS15460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KV103_RS15465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KV103_RS15470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KV103_RS15475	COG0531	amino acid
KV103_RS15485	COG1988	membrane-bound metal-dependent
KV103_RS15490	COG1368	sulfuric ester hydrolase activity
KV103_RS15495	COG1910	domain protein
KV103_RS15500	COG0725	ABC transporter, periplasmic molybdate-binding protein
KV103_RS15505	COG4149	molybdate abc transporter
KV103_RS15510	COG2197	response regulator
KV103_RS15515	COG3850	Histidine kinase
KV103_RS15520	COG1131	(ABC) transporter
KV103_RS15530	COG0842	Transport permease protein
KV103_RS15535	COG0656	L-ascorbic acid biosynthetic process
KV103_RS15555	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KV103_RS15560	COG3973	AAA domain
KV103_RS15565	COG2860	membrane
KV103_RS15575	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KV103_RS15580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KV103_RS15585	COG2217	Heavy metal translocating P-type atpase
KV103_RS15590	COG2217	Heavy metal translocating P-type atpase
KV103_RS15595	COG2608	mercury ion transmembrane transporter activity
KV103_RS15600	COG1937	Protein conserved in bacteria
KV103_RS15605	COG0673	inositol 2-dehydrogenase activity
KV103_RS15615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KV103_RS15620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KV103_RS15625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KV103_RS15630	COG1126	abc transporter atp-binding protein
KV103_RS15635	COG0765	amino acid transport
KV103_RS15640	COG0765	amino acid transport
KV103_RS15645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KV103_RS15650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KV103_RS15655	COG0454	-acetyltransferase
KV103_RS15660	COG0583	DNA-binding transcription factor activity
KV103_RS15665	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS15705	COG0557	exoribonuclease II activity
KV103_RS15710	COG1647	Serine aminopeptidase, S33
KV103_RS15715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KV103_RS15720	COG1476	TRANSCRIPTIONal
KV103_RS15725	COG1396	sequence-specific DNA binding
KV103_RS15730	COG1396	sequence-specific DNA binding
KV103_RS15735	COG1733	regulation of RNA biosynthetic process
KV103_RS15760	COG1131	(ABC) transporter
KV103_RS15765	COG1174	glycine betaine transport
KV103_RS15770	COG1732	Glycine betaine
KV103_RS15775	COG1174	glycine betaine transport
KV103_RS15780	COG1125	glycine betaine transport
KV103_RS15780	COG0517	IMP dehydrogenase activity
KV103_RS15785	COG1510	regulation of RNA biosynthetic process
KV103_RS15790	COG1174	glycine betaine transport
KV103_RS15795	COG1732	Glycine betaine
KV103_RS15800	COG1174	glycine betaine transport
KV103_RS15805	COG0517	IMP dehydrogenase activity
KV103_RS15805	COG1125	glycine betaine transport
KV103_RS15810	COG1510	regulation of RNA biosynthetic process
KV103_RS15815	COG2095	MarC family integral membrane protein
KV103_RS15820	COG3064	Membrane
KV103_RS15825	COG4640	response to antibiotic
KV103_RS15830	COG0456	acetyltransferase
KV103_RS15845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KV103_RS15865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KV103_RS15870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KV103_RS15880	COG2234	aminopeptidase activity
KV103_RS15900	COG0126	phosphoglycerate kinase activity
KV103_RS15905	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KV103_RS15910	COG2390	Transcriptional regulator
KV103_RS15915	COG2814	Major facilitator Superfamily
KV103_RS15920	COG1609	Transcriptional regulator
KV103_RS15925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KV103_RS15935	COG0583	DNA-binding transcription factor activity
KV103_RS15940	COG0697	spore germination
KV103_RS15945	COG1113	amino acid transport
KV103_RS15950	COG1609	Transcriptional regulator
KV103_RS15960	COG0561	phosphatase activity
KV103_RS15965	COG1737	Transcriptional regulator
KV103_RS15970	COG1070	Carbohydrate kinase
KV103_RS16010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KV103_RS16015	COG2186	Transcriptional regulator
KV103_RS16020	COG1620	l-lactate permease
KV103_RS16025	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KV103_RS16035	COG5039	Polysaccharide pyruvyl transferase
KV103_RS16040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KV103_RS16045	COG0110	maltose O-acetyltransferase activity
KV103_RS16050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KV103_RS16055	COG2244	polysaccharide biosynthetic process
KV103_RS16060	COG1216	Glycosyl transferase, family 2
KV103_RS16065	COG5039	Polysaccharide pyruvyl transferase
KV103_RS16070	COG1216	Glycosyl transferase, family 2
KV103_RS16080	COG0438	transferase activity, transferring glycosyl groups
KV103_RS16085	COG1215	transferase activity, transferring glycosyl groups
KV103_RS16090	COG0438	transferase activity, transferring glycosyl groups
KV103_RS16095	COG1086	Polysaccharide biosynthesis protein
KV103_RS16100	COG0489	protein tyrosine kinase activity
KV103_RS16105	COG3944	biosynthesis protein
KV103_RS16110	COG1396	sequence-specific DNA binding
KV103_RS16115	COG2272	Belongs to the type-B carboxylesterase lipase family
KV103_RS16120	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KV103_RS16125	COG2364	Membrane
KV103_RS16130	COG0456	acetyltransferase
KV103_RS16135	COG3479	Phenolic acid decarboxylase
KV103_RS16185	COG2223	nitrite transmembrane transporter activity
KV103_RS16190	COG1609	Transcriptional regulator
KV103_RS16200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KV103_RS16205	COG0366	Alpha amylase catalytic
KV103_RS16210	COG1554	hydrolase, family 65, central catalytic
KV103_RS16215	COG5521	maltodextrose utilization protein MalA
KV103_RS16220	COG3833	ABC-type maltose transport systems, permease component
KV103_RS16225	COG1175	transmembrane transport
KV103_RS16230	COG2182	Extracellular solute-binding protein
KV103_RS16235	COG0366	Alpha amylase catalytic
KV103_RS16240	COG1609	Transcriptional regulator
KV103_RS16245	COG1611	Belongs to the LOG family
KV103_RS16250	COG1694	Mazg nucleotide pyrophosphohydrolase
KV103_RS16255	COG0659	secondary active sulfate transmembrane transporter activity
KV103_RS16260	COG0288	reversible hydration of carbon dioxide
KV103_RS16265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KV103_RS16270	COG4290	ribonuclease
KV103_RS16275	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KV103_RS16280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KV103_RS16290	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KV103_RS16300	COG1051	belongs to the nudix hydrolase family
KV103_RS16305	COG0492	ferredoxin-NADP+ reductase activity
KV103_RS16310	COG0791	NLP P60 protein
KV103_RS16310	COG3883	PFAM NLP P60 protein
KV103_RS16315	COG0457	Tetratricopeptide repeat
KV103_RS16320	COG5002	protein histidine kinase activity
KV103_RS16325	COG0745	RESPONSE REGULATOR receiver
KV103_RS16330	COG1132	(ABC) transporter
KV103_RS16335	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KV103_RS16335	COG0140	phosphoribosyl-ATP diphosphatase activity
KV103_RS16360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KV103_RS16375	COG4990	cell redox homeostasis
KV103_RS16380	COG0110	maltose O-acetyltransferase activity
KV103_RS16400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KV103_RS16410	COG2188	Transcriptional regulator
KV103_RS16415	COG1309	transcriptional regulator
KV103_RS16420	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KV103_RS16425	COG1950	PFAM Membrane protein of
KV103_RS16430	COG1983	PspC domain protein
KV103_RS16435	COG3595	metallopeptidase activity
KV103_RS16450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KV103_RS16460	COG4897	Protein conserved in bacteria
KV103_RS16465	COG3848	Pyruvate phosphate dikinase
KV103_RS16465	COG0574	Belongs to the PEP-utilizing enzyme family
KV103_RS16470	COG1309	transcriptional regulator
KV103_RS16475	COG2814	Major facilitator Superfamily
KV103_RS16490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KV103_RS16500	COG3409	Peptidoglycan-binding domain 1 protein
KV103_RS16500	COG0793	Belongs to the peptidase S41A family
KV103_RS16505	COG3420	alginic acid biosynthetic process
KV103_RS16510	COG2177	Part of the ABC transporter FtsEX involved in
KV103_RS16515	COG2884	Cell division ATP-binding protein ftsE
KV103_RS16520	COG2010	Cytochrome c
KV103_RS16525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KV103_RS16540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KV103_RS16555	COG1516	flagellar protein fliS
KV103_RS16560	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KV103_RS16565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KV103_RS16585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KV103_RS16590	COG1256	bacterial-type flagellum assembly
KV103_RS16590	COG4786	Flagellar basal body rod
KV103_RS16595	COG3418	PFAM FlgN family protein
KV103_RS16600	COG2747	anti-sigma28 factor FlgM
KV103_RS16610	COG1040	competence protein
KV103_RS16620	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KV103_RS16625	COG1307	EDD domain protein, DegV family
KV103_RS16630	COG2197	response regulator
KV103_RS16635	COG4585	Histidine kinase
KV103_RS16640	COG1739	Uncharacterized protein family UPF0029
KV103_RS16645	COG1316	TRANSCRIPTIONal
KV103_RS16650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KV103_RS16655	COG0438	transferase activity, transferring glycosyl groups
KV103_RS16660	COG1215	transferase activity, transferring glycosyl groups
KV103_RS16665	COG3206	protein involved in exopolysaccharide biosynthesis
KV103_RS16670	COG3307	-O-antigen
KV103_RS16675	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KV103_RS16680	COG0297	glycogen (starch) synthase activity
KV103_RS16680	COG0438	transferase activity, transferring glycosyl groups
KV103_RS16685	COG2244	polysaccharide biosynthetic process
KV103_RS16695	COG0860	N-Acetylmuramoyl-L-alanine amidase
KV103_RS16695	COG2247	cell wall binding repeat
KV103_RS16700	COG2247	cell wall binding repeat
KV103_RS16700	COG2385	sporulation resulting in formation of a cellular spore
KV103_RS16710	COG1316	TRANSCRIPTIONal
KV103_RS16715	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KV103_RS16720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KV103_RS16725	COG1134	teichoic acid transport
KV103_RS16730	COG1682	transport, permease protein
KV103_RS16735	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KV103_RS16745	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KV103_RS16750	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KV103_RS16755	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KV103_RS16760	COG4193	domain, Protein
KV103_RS16765	COG1482	cell wall glycoprotein biosynthetic process
KV103_RS16770	COG0697	spore germination
KV103_RS16775	COG0814	amino acid
KV103_RS16785	COG1215	transferase activity, transferring glycosyl groups
KV103_RS16790	COG2814	Major facilitator Superfamily
KV103_RS16795	COG1316	TRANSCRIPTIONal
KV103_RS16800	COG0561	phosphatase activity
KV103_RS16805	COG2433	Pfam Transposase IS66
KV103_RS16810	COG0791	NLP P60 protein
KV103_RS16820	COG2843	Capsule synthesis protein
KV103_RS16830	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KV103_RS16835	COG0697	spore germination
KV103_RS16840	COG0814	amino acid
KV103_RS16850	COG1609	Transcriptional regulator
KV103_RS16855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KV103_RS16865	COG1129	ABC transporter
KV103_RS16870	COG1172	Belongs to the binding-protein-dependent transport system permease family
KV103_RS16875	COG1879	ABC-type sugar transport system periplasmic component
KV103_RS16880	COG3103	Sh3 type 3 domain protein
KV103_RS16885	COG2249	NAD(P)H dehydrogenase (quinone) activity
KV103_RS16890	COG3527	Alpha-acetolactate decarboxylase
KV103_RS16895	COG0028	Belongs to the TPP enzyme family
KV103_RS16900	COG0583	DNA-binding transcription factor activity
KV103_RS16905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KV103_RS16920	COG5337	Spore coat protein CotH
KV103_RS16930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KV103_RS16940	COG0405	Gamma-glutamyltransferase
KV103_RS16945	COG1522	sequence-specific DNA binding
KV103_RS16950	COG2059	Chromate
KV103_RS16955	COG2059	Chromate
KV103_RS16965	COG0655	NAD(P)H dehydrogenase (quinone) activity
KV103_RS16970	COG0583	DNA-binding transcription factor activity
KV103_RS16995	COG5444	nuclease activity
KV103_RS17010	COG3878	Protein conserved in bacteria
KV103_RS17015	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KV103_RS17020	COG4464	protein tyrosine phosphatase activity
KV103_RS17025	COG0489	protein tyrosine kinase activity
KV103_RS17030	COG3944	biosynthesis protein
KV103_RS17040	COG4715	Zinc finger, swim domain protein
KV103_RS17045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KV103_RS17050	COG0561	phosphatase activity
KV103_RS17055	COG1349	DNA-binding transcription factor activity
KV103_RS17060	COG0629	single-stranded DNA binding
KV103_RS17085	COG0457	Tetratricopeptide repeat
KV103_RS17090	COG4786	Flagellar basal body rod
KV103_RS17095	COG4786	Flagellar basal body rod
KV103_RS17100	COG1077	Cell shape determining protein MreB Mrl
KV103_RS17105	COG1609	Transcriptional regulator
KV103_RS17110	COG1846	Transcriptional regulator
KV103_RS17115	COG2814	Major facilitator Superfamily
KV103_RS17120	COG1953	Uracil, thiamine, allantoin
KV103_RS17125	COG0477	Major facilitator Superfamily
KV103_RS17130	COG1335	isochorismatase
KV103_RS17135	COG0004	ammonium transporteR
KV103_RS17140	COG0347	Belongs to the P(II) protein family
KV103_RS17145	COG0772	Belongs to the SEDS family
KV103_RS17150	COG0671	phosphoesterase, PA-phosphatase related
KV103_RS17160	COG0739	heme binding
KV103_RS17165	COG1247	-acetyltransferase
KV103_RS17180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KV103_RS17190	COG0726	polysaccharide deacetylase
KV103_RS17200	COG1959	2 iron, 2 sulfur cluster binding
KV103_RS17215	COG0831	urea catabolic process
KV103_RS17220	COG3237	CsbD-like
KV103_RS17225	COG1994	Peptidase M50
KV103_RS17230	COG0457	Tetratricopeptide repeat
KV103_RS17240	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KV103_RS17250	COG2304	oxidoreductase activity
KV103_RS17255	COG2304	oxidoreductase activity
KV103_RS17260	COG2385	sporulation resulting in formation of a cellular spore
KV103_RS17265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KV103_RS17275	COG4836	Membrane
KV103_RS17345	COG0698	ribose 5-phosphate isomerase
KV103_RS17350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KV103_RS17360	COG0009	L-threonylcarbamoyladenylate synthase
KV103_RS17365	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KV103_RS17385	COG2890	protein-(glutamine-N5) methyltransferase activity
KV103_RS17390	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KV103_RS17395	COG0346	lactoylglutathione lyase activity
KV103_RS17400	COG0789	Transcriptional regulator
KV103_RS17405	COG0679	Auxin Efflux Carrier
KV103_RS17410	COG0281	malic enzyme
KV103_RS17425	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KV103_RS17430	COG1494	fructose-1,6-bisphosphatase
KV103_RS17435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KV103_RS17445	COG0191	fructose-bisphosphate aldolase activity
KV103_RS17450	COG2204	response regulator
KV103_RS17455	COG4821	SIS domain
KV103_RS17470	COG0247	lactate metabolic process
KV103_RS17470	COG2181	nitrate reductase activity
KV103_RS17475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KV103_RS17490	COG1132	(ABC) transporter
KV103_RS17495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KV103_RS17505	COG2181	nitrate reductase activity
KV103_RS17510	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KV103_RS17515	COG1140	nitrate reductase beta subunit
KV103_RS17520	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KV103_RS17525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KV103_RS17535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KV103_RS17540	COG2223	nitrite transmembrane transporter activity
KV103_RS17550	COG4506	Protein conserved in bacteria
KV103_RS17560	COG3391	amine dehydrogenase activity
KV103_RS17565	COG3391	amine dehydrogenase activity
KV103_RS17570	COG0457	Tetratricopeptide repeat
KV103_RS17580	COG0010	Belongs to the arginase family
KV103_RS17585	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KV103_RS17590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KV103_RS17605	COG1994	Peptidase M50
KV103_RS17610	COG1942	4-Oxalocrotonate Tautomerase
KV103_RS17615	COG1846	Transcriptional regulator
KV103_RS17620	COG0531	amino acid
KV103_RS17625	COG3465	dGTPase activity
KV103_RS17630	COG1078	dGTPase activity
KV103_RS17645	COG1695	Transcriptional regulator
KV103_RS17655	COG1131	(ABC) transporter
KV103_RS17660	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KV103_RS17690	COG0583	DNA-binding transcription factor activity
KV103_RS17695	COG2855	membrane
KV103_RS17700	COG0280	phosphate acetyltransferase
KV103_RS17710	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS17715	COG0436	Aminotransferase
KV103_RS17745	COG2814	Major facilitator Superfamily
KV103_RS17750	COG2814	Major facilitator Superfamily
KV103_RS17755	COG0833	amino acid
KV103_RS17760	COG4187	Peptidase family M20/M25/M40
KV103_RS17765	COG1012	belongs to the aldehyde dehydrogenase family
KV103_RS17770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KV103_RS17775	COG2205	protein histidine kinase activity
KV103_RS17780	COG0745	RESPONSE REGULATOR receiver
KV103_RS17795	COG1131	(ABC) transporter
KV103_RS17800	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KV103_RS17805	COG1091	dTDP-4-dehydrorhamnose reductase activity
KV103_RS17810	COG1088	dTDP-glucose 4,6-dehydratase activity
KV103_RS17815	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KV103_RS17820	COG3980	spore coat polysaccharide biosynthesis protein
KV103_RS17825	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KV103_RS17830	COG2089	acid synthase
KV103_RS17835	COG0456	acetyltransferase
KV103_RS17840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KV103_RS17845	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KV103_RS17850	COG0463	Glycosyl transferase, family 2
KV103_RS17860	COG2363	Small membrane protein
KV103_RS17865	COG2233	PERMEase
KV103_RS17880	COG1216	Glycosyl transferase, family 2
KV103_RS17895	COG1695	Transcriptional regulator
KV103_RS17900	COG0351	phosphomethylpyrimidine kinase
KV103_RS17910	COG1621	beta-fructofuranosidase activity
KV103_RS17915	COG1263	PTS System
KV103_RS17915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KV103_RS17920	COG3711	transcriptional antiterminator
KV103_RS17930	COG1404	Belongs to the peptidase S8 family
KV103_RS17935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KV103_RS17940	COG0778	Nitroreductase
KV103_RS17945	COG0772	Belongs to the SEDS family
KV103_RS17950	COG0454	-acetyltransferase
KV103_RS17970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KV103_RS17975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KV103_RS17980	COG2261	transglycosylase associated protein
KV103_RS17985	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KV103_RS17990	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KV103_RS17995	COG2246	polysaccharide biosynthetic process
KV103_RS18000	COG1309	transcriptional regulator
KV103_RS18020	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KV103_RS18025	COG2837	iron assimilation
KV103_RS18045	COG0583	DNA-binding transcription factor activity
KV103_RS18055	COG1346	cytolysis
KV103_RS18060	COG4895	conserved protein (DUF2196)
KV103_RS18065	COG0789	Transcriptional regulator
KV103_RS18070	COG5504	Zn-dependent protease
KV103_RS18075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KV103_RS18080	COG0346	lactoylglutathione lyase activity
KV103_RS18085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV103_RS18090	COG1404	Belongs to the peptidase S8 family
KV103_RS18095	COG1442	glycosyl transferase family 8
KV103_RS18100	COG2357	RelA SpoT domain protein
KV103_RS18105	COG1575	Belongs to the MenA family. Type 1 subfamily
KV103_RS18120	COG1696	Membrane protein involved in D-alanine export
KV103_RS18130	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KV103_RS18135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KV103_RS18140	COG1486	melibiose metabolic process
KV103_RS18145	COG1447	Phosphotransferase system cellobiose-specific component IIA
KV103_RS18150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV103_RS18155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV103_RS18160	COG3711	transcriptional antiterminator
KV103_RS18160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KV103_RS18170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KV103_RS18175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KV103_RS18185	COG0640	Transcriptional regulator
KV103_RS18190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KV103_RS18195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV103_RS18200	COG1447	Phosphotransferase system cellobiose-specific component IIA
KV103_RS18205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV103_RS18210	COG2723	6-phospho-beta-galactosidase activity
KV103_RS18220	COG1482	cell wall glycoprotein biosynthetic process
KV103_RS18230	COG0753	catalase activity
KV103_RS18235	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KV103_RS18240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KV103_RS18260	COG3279	Response regulator of the LytR AlgR family
KV103_RS18280	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KV103_RS18285	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KV103_RS18290	COG4988	ABC transporter
KV103_RS18295	COG1294	oxidase, subunit
KV103_RS18300	COG1271	oxidase subunit
KV103_RS18305	COG3493	citrate carrier protein
KV103_RS18310	COG0726	polysaccharide deacetylase
KV103_RS18315	COG3842	ATPase activity
KV103_RS18320	COG2508	Transcriptional regulator
KV103_RS18325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KV103_RS18335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KV103_RS18350	COG4894	glucomannan catabolic process
KV103_RS18355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KV103_RS18360	COG0500	methyltransferase
KV103_RS18365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KV103_RS18380	COG0753	catalase activity
KV103_RS18380	COG0693	protein deglycase activity
KV103_RS18385	COG2851	Citrate transporter
KV103_RS18390	COG2273	Hydrolase Family 16
KV103_RS18400	COG2270	Major facilitator Superfamily
KV103_RS18405	COG0513	Belongs to the DEAD box helicase family
KV103_RS18415	COG0697	spore germination
KV103_RS18420	COG0589	response to stress
KV103_RS18480	COG3507	Belongs to the glycosyl hydrolase 43 family
KV103_RS18505	COG0010	Belongs to the arginase family
KV103_RS18510	COG0833	amino acid
KV103_RS18515	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KV103_RS18520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KV103_RS18530	COG2390	Transcriptional regulator
KV103_RS18535	COG0561	phosphatase activity
KV103_RS18565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KV103_RS18570	COG5294	Protein conserved in bacteria
KV103_RS18575	COG0577	efflux transmembrane transporter activity
KV103_RS18580	COG1136	(ABC) transporter
KV103_RS18585	COG2205	protein histidine kinase activity
KV103_RS18590	COG0745	RESPONSE REGULATOR receiver
KV103_RS18595	COG2205	protein histidine kinase activity
KV103_RS18600	COG0745	RESPONSE REGULATOR receiver
KV103_RS18630	COG1082	Xylose isomerase domain protein TIM barrel
KV103_RS18640	COG2814	Major facilitator Superfamily
KV103_RS18670	COG1349	DNA-binding transcription factor activity
KV103_RS18675	COG0667	Aldo Keto reductase
KV103_RS18680	COG2814	Major facilitator Superfamily
KV103_RS18690	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS18695	COG2197	response regulator
KV103_RS18700	COG4585	Histidine kinase
KV103_RS18705	COG3239	Fatty acid desaturase
KV103_RS18710	COG1309	transcriptional regulator
KV103_RS18715	COG1012	belongs to the aldehyde dehydrogenase family
KV103_RS18720	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KV103_RS18730	COG0640	Transcriptional regulator
KV103_RS18735	COG2814	Major facilitator Superfamily
KV103_RS18740	COG1714	RDD family
KV103_RS18750	COG0450	alkyl hydroperoxide reductase
KV103_RS18755	COG3634	alkyl hydroperoxide reductase activity
KV103_RS18760	COG3177	Filamentation induced by cAMP protein fic
KV103_RS18765	COG1113	amino acid transport
KV103_RS18775	COG2080	2 iron, 2 sulfur cluster binding
KV103_RS18790	COG2068	MobA-Related Protein
KV103_RS18795	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KV103_RS18850	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KV103_RS18855	COG0667	Aldo Keto reductase
KV103_RS18860	COG0456	acetyltransferase
KV103_RS18865	COG0457	Tetratricopeptide repeat
KV103_RS18870	COG0010	Belongs to the arginase family
KV103_RS18875	COG0833	amino acid
KV103_RS18880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KV103_RS18885	COG5658	integral membrane protein
KV103_RS18890	COG0640	Transcriptional regulator
KV103_RS18895	COG3829	transcription factor binding
KV103_RS18905	COG0488	(ABC) transporter
KV103_RS18920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KV103_RS18925	COG5002	protein histidine kinase activity
KV103_RS18925	COG3850	Histidine kinase
KV103_RS18935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KV103_RS18940	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KV103_RS18945	COG4853	Protein conserved in bacteria
KV103_RS18950	COG4863	YycH protein
KV103_RS18955	COG5002	protein histidine kinase activity
KV103_RS18960	COG0745	RESPONSE REGULATOR receiver
KV103_RS18990	COG0346	lactoylglutathione lyase activity
KV103_RS18995	COG0305	Participates in initiation and elongation during chromosome replication
KV103_RS19010	COG3093	addiction module antidote protein HigA
KV103_RS19020	COG0297	glycogen (starch) synthase activity
KV103_RS19030	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KV103_RS19035	COG0438	transferase activity, transferring glycosyl groups
KV103_RS19055	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KV103_RS19060	COG4241	membrane
KV103_RS19070	COG5577	PFAM Coat F domain
KV103_RS19075	COG1733	regulation of RNA biosynthetic process
KV103_RS19085	COG0697	spore germination
KV103_RS19090	COG1621	beta-fructofuranosidase activity
KV103_RS19095	COG1621	beta-fructofuranosidase activity
KV103_RS19105	COG2318	DinB family
KV103_RS19110	COG2211	Major facilitator Superfamily
KV103_RS19120	COG0778	Nitroreductase
KV103_RS19130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KV103_RS19135	COG1846	Transcriptional regulator
KV103_RS19140	COG2153	protein acetylation
KV103_RS19150	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KV103_RS19155	COG0583	DNA-binding transcription factor activity
KV103_RS19160	COG1028	Short-chain dehydrogenase reductase Sdr
KV103_RS19165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KV103_RS19170	COG0697	spore germination
KV103_RS19200	COG1331	Highly conserved protein containing a thioredoxin domain
KV103_RS19205	COG1266	CAAX protease self-immunity
KV103_RS19210	COG2814	Major facilitator Superfamily
KV103_RS19210	COG0477	Major facilitator Superfamily
KV103_RS19215	COG0346	lactoylglutathione lyase activity
KV103_RS19220	COG1609	Transcriptional regulator
KV103_RS19225	COG0708	Exodeoxyribonuclease III
KV103_RS19230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KV103_RS19235	COG2169	Transcriptional regulator
KV103_RS19245	COG0629	single-stranded DNA binding
KV103_RS19255	COG0012	GTP binding
KV103_RS19260	COG0243	molybdopterin cofactor binding
KV103_RS19265	COG4481	Protein conserved in bacteria
KV103_RS19270	COG3949	Membrane
KV103_RS19285	COG1475	DNA binding
KV103_RS19290	COG1192	Involved in chromosome partitioning
KV103_RS19315	COG1847	R3H domain protein
KV103_RS19320	COG0706	membrane insertase activity
KV103_RS19360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KV103_RS19365	COG5632	N-Acetylmuramoyl-L-alanine amidase
KV103_RS19365	COG1388	LysM domain
KV103_RS19365	COG3409	Peptidoglycan-binding domain 1 protein
KV103_RS19410	COG5434	Belongs to the glycosyl hydrolase 28 family
KV103_RS19415	COG5434	Belongs to the glycosyl hydrolase 28 family
KV103_RS19585	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family